ZAK

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0A2R8Y4L2 S95 Sugiyama HNRNPA1L3 HNRNPA1P48 RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
O00151 T80 Sugiyama PDLIM1 CLIM1 CLP36 NMTHLEAQNRIKGCTDNLtLtVARsEHKVWsPLVtEEGKRH
O00170 T48 Sugiyama AIP XAP2 FQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELIIGKKF
O00267 T709 Sugiyama SUPT5H SPT5 SPT5H GGSGGMSRGRGRRDNELIGQtVRISQGPYKGYIGVVKDATE
O00273 S302 Sugiyama DFFA DFF1 DFF45 H13 TETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDLQN
O14950 T160 Sugiyama MYL12B MRLC2 MYLC2B DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O43290 T430 Sugiyama SART1 RKKEKEVVVRADDLLPLGDQtQDGDFGsRLRGRGRRRVsEV
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43390 T141 Sugiyama HNRNPR HNRPR GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP
O43423 T101 Sugiyama ANP32CP PP32R1 EKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCEV
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43852 S44 Sugiyama CALU KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60231 T110 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 LLEKNRSYRLLEDsEEssEEtVsRAGsSLQKKRKKRKHLRK
O60361 S107 Sugiyama NME2P1 GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDY
O60361 S110 Sugiyama NME2P1 RGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDYKSC
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O60506 T138 Sugiyama SYNCRIP HNRPQ NSAP1 GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP
O60739 T46 Sugiyama EIF1B GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK
O60841 S186 Sugiyama EIF5B IF2 KIAA0741 EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN
O60841 S196 Sugiyama EIF5B IF2 KIAA0741 ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN
O60841 T78 Sugiyama EIF5B IF2 KIAA0741 ILKELEELsLEAQGIKADREtVAVKPTENNEEEFtsKDKKK
O60927 T88 Sugiyama PPP1R11 HCGV TCTE5 RAFGEsstEsDEEEEEGCGHtHCVRGHRKGRRRAtLGPtPt
O75347 S103 Sugiyama TBCA ENEKDLEEAEEyKEARLVLDsVKLEA_______________
O75533 S322 Sugiyama SF3B1 SAP155 DtPGHGsGWAEtPRtDRGGDsIGEtPtPGAsKRKsRWDEtP
O75533 T316 Sugiyama SF3B1 SAP155 tPKtERDtPGHGsGWAEtPRtDRGGDsIGEtPtPGAsKRKs
O75821 S189 Sugiyama EIF3G EIF3S4 CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK
O75822 T33 Sugiyama EIF3J EIF3S1 PRO0391 sWDADAFsVEDPVRKVGGGGtAGGDRWEGEDEDEDVKDNWD
O95218 T50 Sugiyama ZRANB2 ZIS ZNF265 SCNRCGREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQ
O95218 T55 Sugiyama ZRANB2 ZIS ZNF265 GREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQCKTCs
O95626 T105 Sugiyama ANP32D PP32R2 EKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCEV
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95757 S599 Sugiyama HSPA4L APG1 HSPH3 OSP94 sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND
O96017 T68 GPS6|EPSD|PSP CHEK2 CDS1 CHK2 RAD53 NSsQSSHSSSGTLSsLETVStQELYsIPEDQEPEDQEPEEP
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00558 S393 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA
P00558 S399 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558 T369 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV
P00558 T378 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA
P00558 T394 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P04040 S517 Sugiyama CAT LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________
P04040 T511 Sugiyama CAT SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075 T49 Sugiyama ALDOA ALDA GILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDR
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04083 T172 Sugiyama ANXA1 ANX1 LPC1 INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF
P04083 T223 Sugiyama ANXA1 ANX1 LPC1 ARALyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKY
P04083 T226 Sugiyama ANXA1 ANX1 LPC1 LyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKYSKH
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 S321 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792 T180 Sugiyama HSPB1 HSP27 HSP28 EGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsD
P04792 T184 Sugiyama HSPB1 HSP27 HSP28 TVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAA
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05387 S29 Sugiyama RPLP2 D11S2243E RPP2 LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S410 Sugiyama KRT8 CYK8 TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06748 S137 Sugiyama NPM1 NPM VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 S393 Sugiyama PGK2 PGKB GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA
P07205 S399 Sugiyama PGK2 PGKB CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205 T394 Sugiyama PGK2 PGKB GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 S168 Sugiyama TUBB TUBB5 OK/SW-cl.56 GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 T166 Sugiyama TUBB TUBB5 OK/SW-cl.56 GMGTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S391 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S52 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P07900 S641 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD
P07900 T195 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG
P07900 T645 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL
P08195 S292 Sugiyama SLC3A2 MDU1 VAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNY
P08195 S296 Sugiyama SLC3A2 MDU1 DLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNYRGEN
P08195 S410 Sugiyama SLC3A2 MDU1 SLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGNRW
P08195 S598 Sugiyama SLC3A2 MDU1 LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08195 T599 Sugiyama SLC3A2 MDU1 QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH
P08195 Y404 Sugiyama SLC3A2 MDU1 DLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLN
P08238 S383 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S532 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yMtEPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK
P08238 S535 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
P08238 T190 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09234 T11 Sugiyama SNRPC __________MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHK
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09429 S35 Sugiyama HMGB1 HMG1 syAFFVQtCREEHKKKHPDAsVNFsEFsKKCsERWKtMsAK
P09651 S95 Sugiyama HNRNPA1 HNRPA1 RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DPH7 T73 Sugiyama TUBA3C TUBA2 FsEtGAGKHVPRAVFVDLEPtVVDEVRtGtyRQLFHPEQLI
P0DPH7 T80 Sugiyama TUBA3C TUBA2 KHVPRAVFVDLEPtVVDEVRtGtyRQLFHPEQLItGKEDAA
P0DPH7 T82 Sugiyama TUBA3C TUBA2 VPRAVFVDLEPtVVDEVRtGtyRQLFHPEQLItGKEDAANN
P0DPH7 Y83 Sugiyama TUBA3C TUBA2 PRAVFVDLEPtVVDEVRtGtyRQLFHPEQLItGKEDAANNy
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10412 T92 Sugiyama H1-4 H1F4 HIST1H1E DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P10412 T96 Sugiyama H1-4 H1F4 HIST1H1E NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P10809 S453 Sugiyama HSPD1 HSP60 EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK
P10809 S67 Sugiyama HSPD1 HSP60 LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK
P10809 T231 Sugiyama HSPD1 HSP60 LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P10809 T61 Sugiyama HSPD1 HSP60 LQGVDLLADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVA
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T47 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11586 S129 Sugiyama MTHFD1 MTHFC MTHFD INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP
P11940 T319 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KNLDDGIDDERLRKEFsPFGtItsAKVMMEGGRSKGFGFVC
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P13073 S72 Sugiyama COX4I1 COX4 VKHLSASQKALKEKEKASWssLsMDEKVELYRIKFKEsFAE
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S578 Sugiyama EEF2 EF2 LKDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNK
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 T5 Sugiyama EEF2 EF2 ________________MVNFtVDQIRAIMDKKANIRNMsVI
P13639 T735 Sugiyama EEF2 EF2 HRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCPEQV
P13639 Y579 Sugiyama EEF2 EF2 KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13674 T140 Sugiyama P4HA1 P4HA YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P14314 T115 Sugiyama PRKCSH G19P1 GVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQQMAEVtR
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P14625 T675 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 sGNMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIR
P15311 S535 Sugiyama EZR VIL2 EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P15311 S539 Sugiyama EZR VIL2 TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR
P15311 T533 Sugiyama EZR VIL2 NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P16401 T95 Sugiyama H1-5 H1F5 HIST1H1B DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16401 T99 Sugiyama H1-5 H1F5 HIST1H1B NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16402 T93 Sugiyama H1-3 H1F3 HIST1H1D DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16402 T97 Sugiyama H1-3 H1F3 HIST1H1D NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAASGEG
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 T92 Sugiyama H1-2 H1F2 HIST1H1C DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16403 T96 Sugiyama H1-2 H1F2 HIST1H1C NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P18615 S135 Sugiyama NELFE RD RDBP sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG
P18621 S111 Sugiyama RPL17 LLHMLKNAESNAELKGLDVDsLVIEHIQVNKAPKMRRRTYR
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P19105 T159 Sugiyama MYL12A MLCB MRLC3 RLC DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
P19338 S619 Sugiyama NCL RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK
P20290 S126 Sugiyama BTF3 NACB OK/SW-cl.8 VNMFTNQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEM
P20290 T133 Sugiyama BTF3 NACB OK/SW-cl.8 GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ
P20618 S151 Sugiyama PSMB1 PSC5 PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20618 Y158 Sugiyama PSMB1 PSC5 IGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLD
P20674 T105 Sugiyama COX5A EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY
P22090 S204 Sugiyama RPS4Y1 RPS4Y PRO2646 IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22392 S122 Sugiyama NME2 NM23B GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDy
P22392 S125 Sugiyama NME2 NM23B RGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDyKSC
P22626 T140 Sugiyama HNRNPA2B1 HNRPA2B1 KEDTEEHHLRDyFEEYGKIDtIEIItDRQsGKKRGFGFVtF
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23381 T362 Sugiyama WARS1 IFI53 WARS WRS ALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRD
P23381 T364 Sugiyama WARS1 IFI53 WARS WRS QGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRDtI
P23396 S35 Sugiyama RPS3 OK/SW-cl.26 GIFKAELNEFLtRELAEDGysGVEVRVtPTRTEIIILATRT
P23396 T26 Sugiyama RPS3 OK/SW-cl.26 sKKRKFVADGIFKAELNEFLtRELAEDGysGVEVRVtPTRT
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23588 S207 Sugiyama EIF4B DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR
P23588 T205 Sugiyama EIF4B GRDRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYR
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P25705 S198 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK
P25786 T11 Sugiyama PSMA1 HC2 NU PROS30 PSC2 __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26373 S109 Sugiyama RPL13 BBC1 OK/SW-cl.46 KVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILFPR
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26639 S522 Sugiyama TARS1 TARS PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P29692 S37 Sugiyama EEF1D EF1D KYDDAERRFyEQMNGPVAGAsRQENGAsVILRDIARARENI
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P30040 T43 Sugiyama ERP29 C12orf8 ERP28 LLSAPHGGSGLHTKGALPLDtVtFyKVIPKSKFVLVKFDtQ
P30040 T45 Sugiyama ERP29 C12orf8 ERP28 SAPHGGSGLHTKGALPLDtVtFyKVIPKSKFVLVKFDtQyP
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 T135 Sugiyama RPL12 QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30050 T25 Sugiyama RPL12 FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD
P30086 S139 Sugiyama PEBP1 PBP PEBP RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE
P30086 T167 Sugiyama PEBP1 PBP PEBP GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P31943 S285 Sugiyama HNRNPH1 HNRPH HNRPH1 NyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDI
P31948 S16 Sugiyama STIP1 _____MEQVNELKEKGNKALsVGNIDDALQCysEAIKLDPH
P31948 S28 Sugiyama STIP1 KEKGNKALsVGNIDDALQCysEAIKLDPHNHVLysNRsAAy
P31948 T243 Sugiyama STIP1 KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931 T49 Sugiyama HSPA1L EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV
P35269 T41 Sugiyama GTF2F1 RAP74 NTTKKyNIMAFNAADKVNFAtWNQARLERDLSNKKIyQEEE
P35579 S1714 Sugiyama MYH9 RAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQL
P35579 S1916 Sugiyama MYH9 LQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMAR
P35579 T1904 Sugiyama MYH9 EEAQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRG
P35579 T1906 Sugiyama MYH9 AQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRGDL
P35637 S462 Sugiyama FUS TLS NECNQCKAPKPDGPGGGPGGsHMGGNyGDDRRGGRGGYDRG
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37108 T45 Sugiyama SRP14 sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 S59 Sugiyama RPS19 LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019 T55 Sugiyama RPS19 DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019 T60 Sugiyama RPS19 AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P39687 T105 Sugiyama ANP32A C15orf1 LANP MAPM PHAP1 EKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCEV
P40429 T153 Sugiyama RPL13A RKFAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQ
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P41567 T46 Sugiyama EIF1 SUI1 GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P43034 S152 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P46013 S1447 Sugiyama MKI67 EDKSINAFRETAKQKLDPAAsVtGsKRHPKTKEKAQPLEDL
P46379 T1080 GPS6 BAG6 BAT3 G3 QLLLSEAVSRAAKAAGARPLtsPEsLsRDLEAPEVQESYRQ
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46778 T29 Sugiyama RPL21 RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ
P47914 S142 Sugiyama RPL29 KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P51116 S601 Sugiyama FXR2 FMR1L2 RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ
P51116 T610 Sugiyama FXR2 FMR1L2 RRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLER
P51149 T168 Sugiyama RAB7A RAB7 NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE
P51532 S1382 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE
P51858 S83 Sugiyama HDGF HMG1L2 LFPyEEsKEKFGKPNKRKGFsEGLWEIENNPtVKASGYQSs
P51858 T94 Sugiyama HDGF HMG1L2 GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP
P52948 S683 Sugiyama NUP98 ADAR2 IAKPIPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEG
P52948 T687 Sugiyama NUP98 ADAR2 IPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEGssEE
P53999 S17 Sugiyama SUB1 PC4 RPO2TC1 ____MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPV
P53999 S19 Sugiyama SUB1 PC4 RPO2TC1 __MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPVKK
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T48 Sugiyama HSPA2 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI
P55010 T227 Sugiyama EIF5 ttEEAQRRRMDEISDHAKVLtLsDDLERtIEERVNILFDFV
P55010 T235 Sugiyama EIF5 RMDEISDHAKVLtLsDDLERtIEERVNILFDFVKKKKEEGV
P55854 S27 Sugiyama SUMO3 SMT3A SMT3H1 KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P60174 S195 Sugiyama TPI1 TPI KtATPQQAQEVHEKLRGWLKsNVsDAVAQstRIIyGGsVtG
P60174 S204 Sugiyama TPI1 TPI EVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQ
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 S97 Sugiyama TPI1 TPI GEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELIGQKVAHA
P60174 T214 Sugiyama TPI1 TPI KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T38 Sugiyama TPI1 TPI RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP
P60174 T46 Sugiyama TPI1 TPI IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN
P60174 T90 Sugiyama TPI1 TPI VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 T85 Sugiyama MYL6 LDFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVM
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T203 Sugiyama ACTB RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P61247 S203 Sugiyama RPS3A FTE1 MFTL EVVNKLIPDsIGKDIEKACQsIyPLHDVFVRKVKMLKKPKF
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 T93 Sugiyama RPL26 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
P61254 T94 Sugiyama RPL26 YRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDKD
P61313 S100 Sugiyama RPL15 EC45 TCBAP0781 tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW
P61353 T33 Sugiyama RPL27 VLAGRYSGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKV
P61353 T94 Sugiyama RPL27 VyNyNHLMPtRysVDIPLDKtVVNKDVFRDPALKRKARREA
P61353 Y85 Sugiyama RPL27 RSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPA
P61604 S64 Sugiyama HSPE1 AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD
P61604 T45 Sugiyama HSPE1 TVTKGGIMLPEKSQGKVLQAtVVAVGsGsKGKGGEIQPVsV
P61956 S28 Sugiyama SUMO2 SMT3B SMT3H2 EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P61978 S417 Sugiyama HNRNPK HNRPK DLAGsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61978 S77 Sugiyama HNRNPK HNRPK VIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIETI
P61981 T31 Sugiyama YWHAG ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62263 S70 Sugiyama RPS14 PRO2640 KETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGI
P62263 T140 Sugiyama RPS14 PRO2640 ARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL_________
P62263 Y72 Sugiyama RPS14 PRO2640 TICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGITA
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62269 T60 Sugiyama RPS18 D6S218E YAHVVLRKADIDLTKRAGELtEDEVERVItIMQNPRQYKIP
P62269 T69 Sugiyama RPS18 D6S218E DIDLTKRAGELtEDEVERVItIMQNPRQYKIPDWFLNRQKD
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T15 Sugiyama RPS11 ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62316 T40 Sugiyama SNRPD2 SNRPD1 EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62424 T93 Sugiyama RPL7A SURF-3 SURF3 RLKVPPAINQFtQALDRQTAtQLLKLAHKYRPEtKQEKKQR
P62701 S204 Sugiyama RPS4X CCG2 RPS4 SCAR tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62701 T247 Sugiyama RPS4X CCG2 RPS4 SCAR VIGKGNKPWIsLPRGKGIRLtIAEERDKRLAAKQSSG____
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62857 S41 Sugiyama RPS28 tGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLLEs
P62857 S61 Sugiyama RPS28 sIIRNVKGPVREGDVLtLLEsEREARRLR____________
P62857 T57 Sugiyama RPS28 DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________
P62899 T119 Sugiyama RPL31 PNKLytLVtyVPVttFKNLQtVNVDEN______________
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62917 S138 Sugiyama RPL8 EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 T143 Sugiyama RPL8 RGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANR
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62942 T15 Sugiyama FKBP1A FKBP1 FKBP12 ______MGVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGK
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 S123 Sugiyama RPS27A UBA80 UBCEP1 LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK
P62979 S134 Sugiyama RPS27A UBA80 UBCEP1 IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P62979 T147 Sugiyama RPS27A UBA80 UBCEP1 GAGVFMAsHFDRHyCGKCCLtyCFNKPEDK___________
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T203 Sugiyama ACTG1 ACTG RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 T89 Sugiyama YBX1 NSEP1 YB1 RNGyGFINRNDtKEDVFVHQtAIKKNNPRKyLRsVGDGEtV
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68431 S29 EPSD H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J RKstGGKAPRKQLATKAARKsAPATGGVKKPHRyRPGtVAL
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P80723 T222 Sugiyama BASP1 NAP22 PAAsAEEPKPVEAPAANsDQtVtVKE_______________
P80723 T224 Sugiyama BASP1 NAP22 AsAEEPKPVEAPAANsDQtVtVKE_________________
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S7 Sugiyama RPL24 ______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P83881 S32 Sugiyama RPL36A RPL44 GIG15 MIG6 CKKCGKHQPHKVTQYKKGKDsLyAQGKRRYDRKQsGYGGQT
P84098 S122 Sugiyama RPL19 LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P99999 S48 Sugiyama CYCS CYC KTGPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEY
Q00839 T530 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KTTWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtG
Q00839 T532 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 TWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtGKL
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q02539 T95 Sugiyama H1-1 H1F1 HIST1H1A DVEKNNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKAS
Q02539 T99 Sugiyama H1-1 H1F1 HIST1H1A NNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKASSVET
Q02543 T101 Sugiyama RPL18A WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q06830 S152 Sugiyama PRDX1 PAGA PAGB TDPX2 IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV
Q06830 T156 Sugiyama PRDX1 PAGA PAGB TDPX2 KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG
Q07955 S182 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 FVRKEDMTYAVRKLDNTKFRsHEGEtAyIRVKVDGPRsPsy
Q07955 T187 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 DMTYAVRKLDNTKFRsHEGEtAyIRVKVDGPRsPsyGRsRs
Q12904 T280 Sugiyama AIMP1 EMAP2 SCYE1 PDKELNPKKKIWEQIQPDLHtNDECVAtyKGVPFEVKGKGV
Q12904 T287 Sugiyama AIMP1 EMAP2 SCYE1 KKKIWEQIQPDLHtNDECVAtyKGVPFEVKGKGVCRAQTMS
Q12906 S317 Sugiyama ILF3 DRBF MPHOSPH4 NF90 KEAtDAIGHLDRQQREDItQsAQHALRLAAFGQLHKVLGMD
Q13263 S784 Sugiyama TRIM28 KAP1 RNF96 TIF1B DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK
Q13283 T241 Sugiyama G3BP1 G3BP ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP
Q13435 T315 Sugiyama SF3B2 SAP145 EMETDARssLGQsAsEtEEDtVsVsKKEKNRKRRNRKKKKK
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 S168 Sugiyama TUBB3 TUBB4 GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13509 T166 Sugiyama TUBB3 TUBB4 GMGTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14152 S988 Sugiyama EIF3A EIF3S10 KIAA0139 PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN
Q14152 T1378 Sugiyama EIF3A EIF3S10 KIAA0139 AEKDREsLRRTKNEtDEDGWttVRR________________
Q14152 T1379 Sugiyama EIF3A EIF3S10 KIAA0139 EKDREsLRRTKNEtDEDGWttVRR_________________
Q14157 S852 Sugiyama UBAP2L KIAA0144 NICE4 LDyysIPFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASS
Q14157 T23 Sugiyama UBAP2L KIAA0144 NICE4 TSVGTNRARGNWEQPQNQNQtQHKQRPQATAEQIRLAQMIS
Q14157 T246 Sugiyama UBAP2L KIAA0144 NICE4 GHFEPDDGTSAWRtAtEEWGtEDWNEDLsEtKIFtAsNVss
Q14192 T234 Sugiyama FHL2 DRAL SLIM3 CDLyAKKCAGCTNPISGLGGtKyIsFEERQWHNDCFNCKKC
Q14247 S113 Sugiyama CTTN EMS1 DRMDKsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVD
Q14568 S52 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14677 T271 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 KDEEETVTTKHIHItQATEttttRHKRTANPsKtIDLGAAA
Q14847 S99 Sugiyama LASP1 MLN50 ELQsQVRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsN
Q14978 S637 Sugiyama NOLC1 KIAA0035 NS5ATP13 GEKRAssPFRRVREEEIEVDsRVADNsFDAKRGAAGDWGER
Q14978 S643 Sugiyama NOLC1 KIAA0035 NS5ATP13 sPFRRVREEEIEVDsRVADNsFDAKRGAAGDWGERANQVLK
Q14980 S1183 Sugiyama NUMA1 NMP22 NUMA ALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQDHS
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15056 T100 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 KFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRK
Q15185 S72 Sugiyama PTGES3 P23 TEBP EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15293 S159 Sugiyama RCN1 RCN EyKQAtyGyyLGNPAEFHDssDHHtFKKMLPRDERRFKAAD
Q15293 S69 Sugiyama RCN1 RCN PPEDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVD
Q15293 T100 Sugiyama RCN1 RCN sKERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNV
Q15293 T144 Sugiyama RCN1 RCN WKDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtF
Q15293 T211 Sugiyama RCN1 RCN FTAFLHPEEFEHMKEIVVLEtLEDIDKNGDGFVDQDEyIAD
Q15293 T71 Sugiyama RCN1 RCN EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI
Q15427 T14 Sugiyama SF3B4 SAP49 _______MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFL
Q16630 T404 Sugiyama CPSF6 CFIM68 yGRPPPYDRGDyGPPGREMDtARtPLsEAEFEEIMNRNRAI
Q16658 S234 Sugiyama FSCN1 FAN1 HSN SNL LEFRsGKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELF
Q27J81 S1201 Sugiyama INF2 C14orf151 C14orf173 PEsALDtsLDKsFsEDAVtDssGsGtLPRARGRASKGTGKR
Q32P51 S95 Sugiyama HNRNPA1L2 HNRNPA1L TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3ZCM7 S75 Sugiyama TUBB8 SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF6 T165 Sugiyama HSP90AB4P DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S405 Sugiyama HSP90AB3P HSP90BC YMTEPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK
Q58FF7 S408 Sugiyama HSP90AB3P HSP90BC EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
Q58FF7 T169 Sugiyama HSP90AB3P HSP90BC DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
Q58FF8 S305 Sugiyama HSP90AB2P HSP90BB RVVYMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKR
Q58FF8 S308 Sugiyama HSP90AB2P HSP90BB YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE
Q5QJE6 S703 Sugiyama DNTTIP2 ERBP TDIF2 GFPKyFQIGtIVDNPADFyHsRIPKKQRKRTIVEELLADSE
Q5QJE6 T692 Sugiyama DNTTIP2 ERBP TDIF2 PKRFYKKNDRDGFPKyFQIGtIVDNPADFyHsRIPKKQRKR
Q5T3I0 T356 Sugiyama GPATCH4 GPATC4 RKKRQQQEEEDLNLEDRGEEtVLGGGTREAESRACSDGRSR
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6EEV6 S28 Sugiyama SUMO4 SMT3H4 EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC
Q6PEY2 T73 Sugiyama TUBA3E FsEtGAGKHVPRAVFVDLEPtVVDEVRtGtyRQLFHPEQLI
Q6PEY2 T80 Sugiyama TUBA3E KHVPRAVFVDLEPtVVDEVRtGtyRQLFHPEQLITGKEDAA
Q6PEY2 T82 Sugiyama TUBA3E VPRAVFVDLEPtVVDEVRtGtyRQLFHPEQLITGKEDAASN
Q6PEY2 Y83 Sugiyama TUBA3E PRAVFVDLEPtVVDEVRtGtyRQLFHPEQLITGKEDAASNY
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71RC2 S392 Sugiyama LARP4 PP13296 KNRVKPQFRssGGsEHstEGsVsLGDGQLNRYSSRNFPAER
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7RTV0 S53 Sugiyama PHF5A CDSyVRPCTLVRICDECNyGsyQGRCVICGGPGVSDAyyCK
Q7Z417 S655 Sugiyama NUFIP2 KIAA1321 PIG1 LGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsIWNL
Q7Z4S6 S708 Sugiyama KIF21A KIAA1708 KIF2 KIRDTQLERDQVLQNLGsVEsysEEKAKKVRSEYEKKLQAM
Q7Z4V5 S399 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 EPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKKPQSS
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86UE4 S306 Sugiyama MTDH AEG1 LYRIC WNEKSVKLssQIsAGEEKWNsVsPAsAGKRKtEPSAWsQDt
Q86V81 S8 Sugiyama ALYREF ALY BEF THOC4 _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IWX8 S904 Sugiyama CHERP DAN26 SCAF6 KGVGVALDDPyENyRRNKsysFIARMKARDECK________
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TD47 T247 Sugiyama RPS4Y2 RPS4Y2P VIGNGNKPWISLPRGKGIRLtIAEERDKRLAAKQSSG____
Q8WXX5 S215 Sugiyama DNAJC9 EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL
Q92890 S299 Sugiyama UFD1 UFD1L KKVEEDEAGGRFVAFsGEGQsLRKKGRKP____________
Q96CT7 S141 Sugiyama CCDC124 KsHLEVPLEENVNRRVLEEGsVEARTIEDAIAVLsVAEEAA
Q96IZ0 T261 Sugiyama PAWR PAR4 YsRTDRSGFPRYNRDANVsGtLVSSstLEKKIEDLEKEVVR
Q99543 S275 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 RAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEKAKKEAEK
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99733 T58 Sugiyama NAP1L4 NAP2 LAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQVRCA
Q99733 Y55 Sugiyama NAP1L4 NAP2 PRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQV
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BRA2 S41 Sugiyama TXNDC17 TXNL5 QHNGKTIFAyFTGSKDAGGKsWCPDCVQAEPVVREGLKHIS
Q9BRS2 S130 Sugiyama RIOK1 RIO1 DKVLRKFENKINLDKLNVtDsVINKVTEKSRQKEADMYRIK
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BY44 S526 Sugiyama EIF2A CDA02 MSTP004 MSTP089 sPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKLKA
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9H0C2 S286 Sugiyama SLC25A31 AAC4 ANT4 SFEC DCFVKIYQHEGISSFFRGAFsNVLRGTGGALVLVLYDKIKE
Q9H444 S87 Sugiyama CHMP4B C20orf178 SHAX1 QALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEVLK
Q9H444 T103 Sugiyama CHMP4B C20orf178 SHAX1 DGtLstIEFQREALENANtNtEVLKNMGYAAKAMKAAHDNM
Q9H444 T85 Sugiyama CHMP4B C20orf178 SHAX1 ALQALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEV
Q9H444 T88 Sugiyama CHMP4B C20orf178 SHAX1 ALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEVLKN
Q9H788 S124 Sugiyama SH2D4A PPP1R38 SH2A LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NYF8 S198 Sugiyama BCLAF1 BTF KIAA0164 PLKsKsQEEPKDtFEHDPsEsIDEFNKssAtsGDIWPGLsA
Q9NYF8 T190 Sugiyama BCLAF1 BTF KIAA0164 EGEPQEEsPLKsKsQEEPKDtFEHDPsEsIDEFNKssAtsG
Q9NYL2 S165 GPS6|SIGNOR|EPSD|PSP MAP3K20 MLK7 MLTK ZAK HCCS4 GVLKICDFGASRFHNHttHMsLVGTFPWMAPEVIQSLPVSE
Q9NYL2 T161 GPS6|SIGNOR|EPSD|PSP MAP3K20 MLK7 MLTK ZAK HCCS4 IAADGVLKICDFGASRFHNHttHMsLVGTFPWMAPEVIQSL
Q9NYL2 T162 SIGNOR|EPSD|PSP MAP3K20 MLK7 MLTK ZAK HCCS4 AADGVLKICDFGASRFHNHttHMsLVGTFPWMAPEVIQSLP
Q9UII2 S39 Sugiyama ATP5IF1 ATPI ATPIF1 TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF
Q9UMX5 T130 Sugiyama NENF CIR2 SPUF LTHDTTGLTAKELEALDEVFtKVYKAKYPIVGYTARRILNE
Q9UNF1 T92 Sugiyama MAGED2 BCG1 tPEAREAPAtQAssttQLtDtQVLAAENKSLAADTKKQNAD
Q9UNX3 T93 Sugiyama RPL26L1 RPL26P1 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
Q9UNX3 T94 Sugiyama RPL26L1 RPL26P1 YRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDKD
Q9UNZ2 S192 Sugiyama NSFL1C UBXN2C KRQHssQDVHVVLKLWKsGFsLDNGELRSyQDPsNAQFLEs
Q9UQ35 S864 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 VKsGtPPRQGsItsPQANEQsVtPQRRsCFEssPDPELKsR
Q9UQ35 T1655 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 RSRSGSSSKGRGPsPEGssstEssPEHPPKSRTARRGsRSs
Q9UQ80 T200 Sugiyama PA2G4 EBP1 TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV
Q9UQ80 T386 Sugiyama PA2G4 EBP1 tQKKKKKKAsKtAENAtsGEtLEENEAGD____________
Q9Y2B0 S115 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2B0 T132 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF
Q9Y2T7 T124 Sugiyama YBX2 CSDA3 MSY2 RNGyGFINRNDtKEDVFVHQtAIKRNNPRKFLRsVGDGEtV
Q9Y2T7 T143 Sugiyama YBX2 CSDA3 MSY2 QtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEATNVTGP
Q9Y2X3 S434 Sugiyama NOP58 NOL5 NOP5 HSPC120 AKTEKYEHKSEVKtyDPSGDstLPtCsKKRKIEQVDKEDEI
Q9Y2X3 T427 Sugiyama NOP58 NOL5 NOP5 HSPC120 SGTGKALAKTEKYEHKSEVKtyDPSGDstLPtCsKKRKIEQ
Q9Y2X3 T435 Sugiyama NOP58 NOL5 NOP5 HSPC120 KTEKYEHKSEVKtyDPSGDstLPtCsKKRKIEQVDKEDEIT
Q9Y3U8 S91 Sugiyama RPL36 KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y450 S67 Sugiyama HBS1L HBS1 KIAA1038 KPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCLDH
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Axon guidance R-HSA-422475 9.969803e-14 13.001 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.739386e-12 11.760 0 0
Nervous system development R-HSA-9675108 2.165046e-12 11.665 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 7.640333e-12 11.117 0 0
Aggrephagy R-HSA-9646399 1.993505e-11 10.700 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.265710e-11 10.645 0 0
Post NMDA receptor activation events R-HSA-438064 2.918388e-11 10.535 0 0
Signal Transduction R-HSA-162582 6.293988e-11 10.201 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.482767e-10 9.829 0 0
Mitotic Prometaphase R-HSA-68877 1.571495e-10 9.804 0 0
Selective autophagy R-HSA-9663891 1.915567e-10 9.718 0 0
Mitotic Anaphase R-HSA-68882 2.580997e-10 9.588 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.910079e-10 9.536 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 3.398065e-10 9.469 0 0
Transport of connexons to the plasma membrane R-HSA-190872 5.773103e-10 9.239 0 0
PKR-mediated signaling R-HSA-9833482 7.781273e-10 9.109 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 8.800396e-10 9.055 0 0
Cell Cycle, Mitotic R-HSA-69278 1.000451e-09 9.000 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.710788e-09 8.767 0 0
Separation of Sister Chromatids R-HSA-2467813 1.907635e-09 8.720 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 2.459033e-09 8.609 0 0
Autophagy R-HSA-9612973 2.401830e-09 8.619 0 0
M Phase R-HSA-68886 2.532730e-09 8.596 0 0
Cell Cycle R-HSA-1640170 4.769096e-09 8.322 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 6.858447e-09 8.164 0 0
Signaling by ERBB2 R-HSA-1227986 8.016910e-09 8.096 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 8.820325e-09 8.055 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.304548e-08 7.885 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.565150e-08 7.805 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.954739e-08 7.709 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.190469e-08 7.659 0 0
Kinesins R-HSA-983189 4.381359e-08 7.358 0 0
Macroautophagy R-HSA-1632852 5.045637e-08 7.297 0 0
Apoptotic execution phase R-HSA-75153 5.448164e-08 7.264 0 0
Recycling pathway of L1 R-HSA-437239 6.963320e-08 7.157 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 7.885015e-08 7.103 0 0
Semaphorin interactions R-HSA-373755 8.241488e-08 7.084 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 9.331100e-08 7.030 0 0
Gap junction trafficking and regulation R-HSA-157858 1.119820e-07 6.951 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 2.202428e-07 6.657 0 0
L1CAM interactions R-HSA-373760 2.180731e-07 6.661 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 2.575252e-07 6.589 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 3.371893e-07 6.472 0 0
Gap junction assembly R-HSA-190861 4.485039e-07 6.348 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 7.379595e-07 6.132 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 8.557408e-07 6.068 0 0
Oncogenic MAPK signaling R-HSA-6802957 9.140829e-07 6.039 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.082503e-06 5.966 0 0
Gap junction trafficking R-HSA-190828 1.109605e-06 5.955 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.284207e-06 5.891 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.445078e-06 5.840 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.600135e-06 5.796 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.814614e-06 5.741 0 0
MHC class II antigen presentation R-HSA-2132295 1.882513e-06 5.725 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.037602e-06 5.691 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.212515e-06 5.655 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 2.428328e-06 5.615 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.443929e-06 5.612 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 2.371858e-06 5.625 0 0
Intraflagellar transport R-HSA-5620924 2.586794e-06 5.587 0 0
RAF activation R-HSA-5673000 2.772874e-06 5.557 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 2.887001e-06 5.540 0 0
Protein folding R-HSA-391251 3.420388e-06 5.466 0 0
Interferon Signaling R-HSA-913531 3.462095e-06 5.461 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.685289e-06 5.434 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 3.675866e-06 5.435 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 3.796131e-06 5.421 0 0
MAPK family signaling cascades R-HSA-5683057 3.836574e-06 5.416 0 0
Apoptosis R-HSA-109581 6.016980e-06 5.221 0 0
G2/M Transition R-HSA-69275 7.436551e-06 5.129 0 0
Signaling by RAS mutants R-HSA-6802949 8.671813e-06 5.062 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 8.671813e-06 5.062 0 0
Signaling downstream of RAS mutants R-HSA-9649948 8.671813e-06 5.062 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 8.671813e-06 5.062 0 0
Signaling by VEGF R-HSA-194138 8.667648e-06 5.062 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 8.466458e-06 5.072 0 0
Signaling by PTK6 R-HSA-8848021 8.466458e-06 5.072 0 0
Mitotic G2-G2/M phases R-HSA-453274 8.851477e-06 5.053 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.049750e-05 4.979 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.167148e-05 4.933 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.593431e-05 4.798 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.593431e-05 4.798 0 0
Membrane Trafficking R-HSA-199991 1.766974e-05 4.753 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 2.021753e-05 4.694 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.132001e-05 4.671 0 0
COPI-mediated anterograde transport R-HSA-6807878 2.329692e-05 4.633 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 2.338746e-05 4.631 0 0
Signaling by KIT in disease R-HSA-9669938 2.338746e-05 4.631 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.387269e-05 4.622 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 2.799408e-05 4.553 0 0
Programmed Cell Death R-HSA-5357801 3.797265e-05 4.421 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 3.820133e-05 4.418 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.966258e-05 4.304 0 0
Cellular responses to stress R-HSA-2262752 4.749187e-05 4.323 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 7.820653e-05 4.107 0 0
Cellular responses to stimuli R-HSA-8953897 8.320467e-05 4.080 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.069900e-04 3.971 0 0
Signaling by SCF-KIT R-HSA-1433557 1.093899e-04 3.961 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 1.147847e-04 3.940 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.147847e-04 3.940 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.167226e-04 3.933 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.189573e-04 3.925 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.465455e-04 3.834 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.552537e-04 3.809 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.689498e-04 3.772 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.985616e-04 3.702 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.985616e-04 3.702 0 0
SOS-mediated signalling R-HSA-112412 2.150259e-04 3.668 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 2.326061e-04 3.633 0 0
MET activates RAS signaling R-HSA-8851805 2.381073e-04 3.623 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.529036e-04 3.597 0 0
HCMV Early Events R-HSA-9609690 2.662593e-04 3.575 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.714217e-04 3.566 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.859070e-04 3.544 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.889331e-04 3.539 0 0
Developmental Biology R-HSA-1266738 3.014271e-04 3.521 0 0
HCMV Infection R-HSA-9609646 3.279980e-04 3.484 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.317258e-04 3.479 0 0
Signaling by RAF1 mutants R-HSA-9656223 3.409937e-04 3.467 0 0
MAP2K and MAPK activation R-HSA-5674135 3.409937e-04 3.467 0 0
Hedgehog 'off' state R-HSA-5610787 3.599101e-04 3.444 0 0
Cilium Assembly R-HSA-5617833 4.165676e-04 3.380 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.350726e-04 3.361 0 0
Cell Cycle Checkpoints R-HSA-69620 5.182988e-04 3.285 0 0
Signaling by ERBB4 R-HSA-1236394 5.267777e-04 3.278 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 5.344125e-04 3.272 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 5.344125e-04 3.272 0 0
Erythropoietin activates RAS R-HSA-9027284 5.850890e-04 3.233 0 0
SHC1 events in EGFR signaling R-HSA-180336 5.850890e-04 3.233 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 5.850890e-04 3.233 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 5.850890e-04 3.233 0 0
AURKA Activation by TPX2 R-HSA-8854518 7.009334e-04 3.154 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 7.617335e-04 3.118 0 0
Transmission across Chemical Synapses R-HSA-112315 8.698243e-04 3.061 0 0
Downstream signal transduction R-HSA-186763 9.064103e-04 3.043 0 0
Interleukin-2 signaling R-HSA-9020558 9.740513e-04 3.011 0 0
Adaptive Immune System R-HSA-1280218 1.071125e-03 2.970 0 0
Integrin signaling R-HSA-354192 1.261665e-03 2.899 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.192646e-03 2.923 0 0
Signaling by Hippo R-HSA-2028269 1.236136e-03 2.908 0 0
FLT3 Signaling R-HSA-9607240 1.192646e-03 2.923 0 0
EPH-Ephrin signaling R-HSA-2682334 1.289935e-03 2.889 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.322777e-03 2.879 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.371733e-03 2.863 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 1.429460e-03 2.845 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 1.429460e-03 2.845 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.457341e-03 2.836 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.464297e-03 2.834 0 0
Signaling by EGFR in Cancer R-HSA-1643713 1.749063e-03 2.757 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.641034e-03 2.785 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.641034e-03 2.785 0 0
GRB2 events in EGFR signaling R-HSA-179812 1.743492e-03 2.759 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 1.749063e-03 2.757 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.695823e-03 2.771 0 0
Vesicle-mediated transport R-HSA-5653656 1.710018e-03 2.767 0 0
Signaling by Hedgehog R-HSA-5358351 1.842533e-03 2.735 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 1.908921e-03 2.719 0 0
Signalling to ERKs R-HSA-187687 1.993453e-03 2.700 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.075052e-03 2.683 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 2.090835e-03 2.680 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.334466e-03 2.632 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.334466e-03 2.632 0 0
Signaling by EGFR R-HSA-177929 2.467071e-03 2.608 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 2.827716e-03 2.549 0 0
Signalling to RAS R-HSA-167044 2.827716e-03 2.549 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 2.866242e-03 2.543 0 0
CRMPs in Sema3A signaling R-HSA-399956 2.885132e-03 2.540 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 2.885132e-03 2.540 0 0
Activation of RAS in B cells R-HSA-1169092 2.937933e-03 2.532 0 0
Immune System R-HSA-168256 3.304195e-03 2.481 0 0
DAP12 signaling R-HSA-2424491 3.339515e-03 2.476 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 3.395065e-03 2.469 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.395065e-03 2.469 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.447180e-03 2.463 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 3.623286e-03 2.441 0 0
p38MAPK events R-HSA-171007 3.623286e-03 2.441 0 0
Signaling by NTRKs R-HSA-166520 3.749811e-03 2.426 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.914443e-03 2.407 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 3.993758e-03 2.399 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.153543e-03 2.382 0 0
Cell-Cell communication R-HSA-1500931 4.245245e-03 2.372 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 4.404001e-03 2.356 0 0
PKMTs methylate histone lysines R-HSA-3214841 4.429131e-03 2.354 0 0
Neuronal System R-HSA-112316 4.781795e-03 2.320 0 0
Viral Infection Pathways R-HSA-9824446 4.894862e-03 2.310 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 5.607040e-03 2.251 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 5.120542e-03 2.291 0 0
Centrosome maturation R-HSA-380287 5.252240e-03 2.280 0 0
Neurodegenerative Diseases R-HSA-8863678 5.607040e-03 2.251 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 5.607040e-03 2.251 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 5.389956e-03 2.268 0 0
Receptor Mediated Mitophagy R-HSA-8934903 5.280197e-03 2.277 0 0
Cell junction organization R-HSA-446728 5.363096e-03 2.271 0 0
Signaling by FGFR1 in disease R-HSA-5655302 4.994299e-03 2.302 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 5.849066e-03 2.233 0 0
Signaling by FGFR4 R-HSA-5654743 6.288538e-03 2.201 0 0
HIV Life Cycle R-HSA-162587 6.327187e-03 2.199 0 0
Long-term potentiation R-HSA-9620244 6.536335e-03 2.185 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 7.023933e-03 2.153 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 7.452583e-03 2.128 0 0
SARS-CoV-2-host interactions R-HSA-9705683 7.460218e-03 2.127 0 0
Signaling by FGFR1 R-HSA-5654736 7.676616e-03 2.115 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 7.822440e-03 2.107 0 0
Signaling by FGFR3 R-HSA-5654741 7.822440e-03 2.107 0 0
Tie2 Signaling R-HSA-210993 7.950057e-03 2.100 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 7.965462e-03 2.099 0 0
Nuclear Envelope Breakdown R-HSA-2980766 8.436265e-03 2.074 0 0
FLT3 signaling in disease R-HSA-9682385 8.500958e-03 2.071 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 8.722310e-03 2.059 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 9.276993e-03 2.033 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 9.682389e-03 2.014 0 0
Signaling by Erythropoietin R-HSA-9006335 1.138758e-02 1.944 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.138758e-02 1.944 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.062878e-02 1.974 0 0
Co-stimulation by CD28 R-HSA-389356 1.062878e-02 1.974 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.120396e-02 1.951 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.105954e-02 1.956 0 0
ESR-mediated signaling R-HSA-8939211 1.101084e-02 1.958 0 0
Pyroptosis R-HSA-5620971 9.991887e-03 2.000 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.077905e-02 1.967 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 1.138758e-02 1.944 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.072078e-02 1.970 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.141520e-02 1.943 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.194508e-02 1.923 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.231084e-02 1.910 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 1.291549e-02 1.889 0 0
Interleukin-6 signaling R-HSA-1059683 1.311907e-02 1.882 0 0
Signaling by PDGF R-HSA-186797 1.311991e-02 1.882 0 0
Interleukin-2 family signaling R-HSA-451927 1.328945e-02 1.876 0 0
HIV Infection R-HSA-162906 1.332953e-02 1.875 0 0
Interleukin-12 family signaling R-HSA-447115 1.433468e-02 1.844 0 0
Neutrophil degranulation R-HSA-6798695 1.437259e-02 1.842 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 1.497586e-02 1.825 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.497586e-02 1.825 0 0
Regulation of TP53 Activity R-HSA-5633007 1.514068e-02 1.820 0 0
Diseases of programmed cell death R-HSA-9645723 1.534779e-02 1.814 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.558889e-02 1.807 0 0
Hemostasis R-HSA-109582 1.574081e-02 1.803 0 0
Regulation of KIT signaling R-HSA-1433559 1.583413e-02 1.800 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.583413e-02 1.800 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.924372e-02 1.716 0 0
Regulation of TP53 Expression R-HSA-6804754 1.924372e-02 1.716 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.924372e-02 1.716 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.924372e-02 1.716 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.924372e-02 1.716 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.924372e-02 1.716 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 1.639766e-02 1.785 0 0
Notch-HLH transcription pathway R-HSA-350054 1.722444e-02 1.764 0 0
Meiotic synapsis R-HSA-1221632 1.686671e-02 1.773 0 0
p75NTR signals via NF-kB R-HSA-193639 1.887781e-02 1.724 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.753416e-02 1.756 0 0
mTORC1-mediated signalling R-HSA-166208 1.722444e-02 1.764 0 0
MTOR signalling R-HSA-165159 1.796989e-02 1.745 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.887781e-02 1.724 0 0
DCC mediated attractive signaling R-HSA-418885 1.887781e-02 1.724 0 0
Metabolism of RNA R-HSA-8953854 1.619740e-02 1.791 0 0
Ca-dependent events R-HSA-111996 1.796989e-02 1.745 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.835030e-02 1.736 0 0
Signaling by MET R-HSA-6806834 1.995714e-02 1.700 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 2.046367e-02 1.689 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 2.046367e-02 1.689 0 0
Type I hemidesmosome assembly R-HSA-446107 2.100734e-02 1.678 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 2.100734e-02 1.678 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 2.100734e-02 1.678 0 0
Interleukin-9 signaling R-HSA-8985947 2.100734e-02 1.678 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 2.100734e-02 1.678 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.150413e-02 1.667 0 0
DAP12 interactions R-HSA-2172127 2.166887e-02 1.664 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.273625e-02 1.643 0 0
Nuclear import of Rev protein R-HSA-180746 2.273625e-02 1.643 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 2.483152e-02 1.605 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 2.500564e-02 1.602 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 2.517261e-02 1.599 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 2.517261e-02 1.599 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 2.598909e-02 1.585 0 0
Interleukin-21 signaling R-HSA-9020958 2.625404e-02 1.581 0 0
GP1b-IX-V activation signalling R-HSA-430116 2.625404e-02 1.581 0 0
Metabolism of non-coding RNA R-HSA-194441 2.739462e-02 1.562 0 0
snRNP Assembly R-HSA-191859 2.739462e-02 1.562 0 0
MET activates STAT3 R-HSA-8875791 2.905472e-02 1.537 0 0
Axonal growth stimulation R-HSA-209563 2.905472e-02 1.537 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 3.213592e-02 1.493 0 0
Folding of actin by CCT/TriC R-HSA-390450 3.213592e-02 1.493 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 3.007105e-02 1.522 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 3.178891e-02 1.498 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.981377e-02 1.526 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.985963e-02 1.525 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.128820e-02 1.505 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 3.213592e-02 1.493 0 0
Ephrin signaling R-HSA-3928664 3.451047e-02 1.462 0 0
Chaperone Mediated Autophagy R-HSA-9613829 3.451047e-02 1.462 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.350483e-02 1.475 0 0
Regulation of CDH11 function R-HSA-9762292 3.213592e-02 1.493 0 0
Formation of the cornified envelope R-HSA-6809371 3.382504e-02 1.471 0 0
Interleukin-27 signaling R-HSA-9020956 3.213592e-02 1.493 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 3.451047e-02 1.462 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 3.451047e-02 1.462 0 0
DNA Repair R-HSA-73894 3.240152e-02 1.489 0 0
Chromatin modifying enzymes R-HSA-3247509 3.089619e-02 1.510 0 0
GPER1 signaling R-HSA-9634597 3.058402e-02 1.515 0 0
Chromatin organization R-HSA-4839726 3.062028e-02 1.514 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 3.350483e-02 1.475 0 0
Signaling by ROBO receptors R-HSA-376176 2.887003e-02 1.540 0 0
Calmodulin induced events R-HSA-111933 2.777697e-02 1.556 0 0
CaM pathway R-HSA-111997 2.777697e-02 1.556 0 0
Cellular response to chemical stress R-HSA-9711123 3.453705e-02 1.462 0 0
Interleukin-12 signaling R-HSA-9020591 3.618590e-02 1.441 0 0
Influenza Infection R-HSA-168255 3.626283e-02 1.441 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.652725e-02 1.437 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.663502e-02 1.436 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.663502e-02 1.436 0 0
Signaling by Interleukins R-HSA-449147 3.697734e-02 1.432 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 3.717121e-02 1.430 0 0
Cellular Senescence R-HSA-2559583 3.770477e-02 1.424 0 0
IGF1R signaling cascade R-HSA-2428924 3.909563e-02 1.408 0 0
Late endosomal microautophagy R-HSA-9615710 3.926425e-02 1.406 0 0
STING mediated induction of host immune responses R-HSA-1834941 3.931009e-02 1.405 0 0
PTEN Regulation R-HSA-6807070 3.988325e-02 1.399 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 3.994655e-02 1.399 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.994655e-02 1.399 0 0
DNA Double-Strand Break Repair R-HSA-5693532 4.042622e-02 1.393 0 0
Regulation of gap junction activity R-HSA-191650 4.043476e-02 1.393 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 4.043476e-02 1.393 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 4.043476e-02 1.393 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 4.043476e-02 1.393 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 4.043476e-02 1.393 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 4.178191e-02 1.379 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 4.178191e-02 1.379 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 4.337020e-02 1.363 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 4.577188e-02 1.339 0 0
Signaling by FGFR2 R-HSA-5654738 4.605083e-02 1.337 0 0
DNA Double Strand Break Response R-HSA-5693606 4.751470e-02 1.323 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 4.772440e-02 1.321 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 4.772440e-02 1.321 0 0
Translation initiation complex formation R-HSA-72649 4.809678e-02 1.318 0 0
Disease R-HSA-1643685 5.066991e-02 1.295 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 5.077131e-02 1.294 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 5.124106e-02 1.290 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 5.124106e-02 1.290 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 6.717219e-02 1.173 0 0
p75NTR recruits signalling complexes R-HSA-209543 5.349851e-02 1.272 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 6.180671e-02 1.209 0 0
Adenylate cyclase activating pathway R-HSA-170660 6.180671e-02 1.209 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 6.869559e-02 1.163 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.718145e-02 1.243 0 0
HDACs deacetylate histones R-HSA-3214815 5.152704e-02 1.288 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 5.510754e-02 1.259 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 6.272308e-02 1.203 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 6.400816e-02 1.194 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 5.618166e-02 1.250 0 0
Interleukin-15 signaling R-HSA-8983432 5.349851e-02 1.272 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 6.675942e-02 1.175 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 5.232800e-02 1.281 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 6.717219e-02 1.173 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 6.400816e-02 1.194 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 5.587320e-02 1.253 0 0
Mitophagy R-HSA-5205647 6.763625e-02 1.170 0 0
Interleukin-35 Signalling R-HSA-8984722 5.349851e-02 1.272 0 0
Meiosis R-HSA-1500620 6.070364e-02 1.217 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 6.717219e-02 1.173 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 6.717219e-02 1.173 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.703495e-02 1.244 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 5.618166e-02 1.250 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 5.349851e-02 1.272 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 5.319766e-02 1.274 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 6.717219e-02 1.173 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 6.180671e-02 1.209 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 6.180671e-02 1.209 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 6.373136e-02 1.196 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.647320e-02 1.177 0 0
EPHB-mediated forward signaling R-HSA-3928662 5.929488e-02 1.227 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.400816e-02 1.194 0 0
Mitotic Prophase R-HSA-68875 5.479412e-02 1.261 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 6.228451e-02 1.206 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 6.400816e-02 1.194 0 0
Deubiquitination R-HSA-5688426 6.091723e-02 1.215 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 6.717219e-02 1.173 0 0
Signaling by LTK R-HSA-9842663 5.349851e-02 1.272 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 6.717219e-02 1.173 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 5.319766e-02 1.274 0 0
NrCAM interactions R-HSA-447038 5.319766e-02 1.274 0 0
Signaling by FGFR R-HSA-190236 6.612343e-02 1.180 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 5.587320e-02 1.253 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 6.210907e-02 1.207 0 0
DAG and IP3 signaling R-HSA-1489509 6.373136e-02 1.196 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 5.510754e-02 1.259 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 6.717219e-02 1.173 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 6.835787e-02 1.165 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 6.763625e-02 1.170 0 0
FOXO-mediated transcription R-HSA-9614085 6.929525e-02 1.159 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 7.067473e-02 1.151 0 0
Signaling by FGFR in disease R-HSA-1226099 7.148899e-02 1.146 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 7.317410e-02 1.136 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 7.323510e-02 1.135 0 0
PLC beta mediated events R-HSA-112043 7.529071e-02 1.123 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 7.562680e-02 1.121 0 0
Interleukin-6 family signaling R-HSA-6783589 7.562680e-02 1.121 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 7.562680e-02 1.121 0 0
G2/M Checkpoints R-HSA-69481 7.654134e-02 1.116 0 0
RET signaling R-HSA-8853659 7.907886e-02 1.102 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 7.907886e-02 1.102 0 0
Regulation of TP53 Degradation R-HSA-6804757 7.907886e-02 1.102 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 7.921447e-02 1.101 0 0
tRNA processing in the nucleus R-HSA-6784531 7.978553e-02 1.098 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 7.978553e-02 1.098 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 7.981496e-02 1.098 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 8.007857e-02 1.096 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 8.007857e-02 1.096 0 0
Other semaphorin interactions R-HSA-416700 8.007857e-02 1.096 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 8.190131e-02 1.087 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 8.220097e-02 1.085 0 0
Nef and signal transduction R-HSA-164944 8.220097e-02 1.085 0 0
Tight junction interactions R-HSA-420029 8.289559e-02 1.081 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 8.289559e-02 1.081 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 8.289559e-02 1.081 0 0
DNA Damage Bypass R-HSA-73893 8.337270e-02 1.079 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 8.516474e-02 1.070 0 0
Cell-cell junction organization R-HSA-421270 8.557468e-02 1.068 0 0
Cap-dependent Translation Initiation R-HSA-72737 8.656565e-02 1.063 0 0
Eukaryotic Translation Initiation R-HSA-72613 8.656565e-02 1.063 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 8.658359e-02 1.063 0 0
Opioid Signalling R-HSA-111885 8.658359e-02 1.063 0 0
Response of endothelial cells to shear stress R-HSA-9860931 8.658359e-02 1.063 0 0
Clathrin-mediated endocytosis R-HSA-8856828 8.796356e-02 1.056 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 9.985942e-02 1.001 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 9.985942e-02 1.001 0 0
Diseases of Telomere Maintenance R-HSA-9673013 9.985942e-02 1.001 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 9.985942e-02 1.001 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 9.985942e-02 1.001 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 9.985942e-02 1.001 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 9.985942e-02 1.001 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 9.985942e-02 1.001 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 9.985942e-02 1.001 0 0
TICAM1 deficiency - HSE R-HSA-5602566 9.985942e-02 1.001 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 9.985942e-02 1.001 0 0
IFNG signaling activates MAPKs R-HSA-9732724 9.813955e-02 1.008 0 0
Disinhibition of SNARE formation R-HSA-114516 9.813955e-02 1.008 0 0
Recycling of eIF2:GDP R-HSA-72731 9.813955e-02 1.008 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 9.813955e-02 1.008 0 0
ARMS-mediated activation R-HSA-170984 1.322275e-01 0.879 0 0
Regulated proteolysis of p75NTR R-HSA-193692 1.322275e-01 0.879 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 1.322275e-01 0.879 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 1.322275e-01 0.879 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 8.999241e-02 1.046 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 8.999241e-02 1.046 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 1.112399e-01 0.954 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.112399e-01 0.954 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 9.841249e-02 1.007 0 0
Packaging Of Telomere Ends R-HSA-171306 9.841249e-02 1.007 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.048386e-01 0.979 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.265389e-01 0.898 0 0
Ribosome-associated quality control R-HSA-9948299 1.222197e-01 0.913 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 1.225161e-01 0.912 0 0
Chromosome Maintenance R-HSA-73886 1.049298e-01 0.979 0 0
Telomere Maintenance R-HSA-157579 1.208855e-01 0.918 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 9.049385e-02 1.043 0 0
p75NTR regulates axonogenesis R-HSA-193697 1.322275e-01 0.879 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 1.148555e-01 0.940 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 1.190893e-01 0.924 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 9.841249e-02 1.007 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 9.841249e-02 1.007 0 0
RAS processing R-HSA-9648002 9.804880e-02 1.009 0 0
Adipogenesis R-HSA-9843745 9.258509e-02 1.033 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.186215e-01 0.926 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 1.225161e-01 0.912 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 1.048386e-01 0.979 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 1.048386e-01 0.979 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 8.999241e-02 1.046 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.031115e-02 1.044 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.003890e-01 0.998 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.225161e-01 0.912 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.118539e-01 0.951 0 0
Regulation of CDH1 Function R-HSA-9764561 1.314520e-01 0.881 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 9.928013e-02 1.003 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.147968e-01 0.940 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 9.416875e-02 1.026 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.147968e-01 0.940 0 0
Inhibition of PKR R-HSA-169131 9.985942e-02 1.001 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 1.322275e-01 0.879 0 0
Synaptic adhesion-like molecules R-HSA-8849932 1.225161e-01 0.912 0 0
PKA activation in glucagon signalling R-HSA-164378 1.225161e-01 0.912 0 0
Diseases of Immune System R-HSA-5260271 1.048386e-01 0.979 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 1.048386e-01 0.979 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.024519e-01 0.989 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.021358e-01 0.991 0 0
Developmental Cell Lineages R-HSA-9734767 1.165226e-01 0.934 0 0
Signaling by ALK in cancer R-HSA-9700206 1.021358e-01 0.991 0 0
G-protein mediated events R-HSA-112040 1.045277e-01 0.981 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 9.813955e-02 1.008 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 9.813955e-02 1.008 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 9.699099e-02 1.013 0 0
Host Interactions of HIV factors R-HSA-162909 1.169620e-01 0.932 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 1.151704e-01 0.939 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.304155e-01 0.885 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 9.841249e-02 1.007 0 0
Activation of BH3-only proteins R-HSA-114452 1.239877e-01 0.907 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.322275e-01 0.879 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.160837e-01 0.935 0 0
MECP2 regulates transcription factors R-HSA-9022707 9.813955e-02 1.008 0 0
PKA activation R-HSA-163615 1.225161e-01 0.912 0 0
Interaction between L1 and Ankyrins R-HSA-445095 9.841249e-02 1.007 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.048386e-01 0.979 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.118539e-01 0.951 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.282970e-01 0.892 0 0
Platelet sensitization by LDL R-HSA-432142 1.225161e-01 0.912 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 1.066416e-01 0.972 0 0
Regulated Necrosis R-HSA-5218859 1.099220e-01 0.959 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 9.813955e-02 1.008 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.322275e-01 0.879 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 1.322275e-01 0.879 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 1.248320e-01 0.904 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.322275e-01 0.879 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 9.049385e-02 1.043 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.265389e-01 0.898 0 0
Gene Silencing by RNA R-HSA-211000 1.021358e-01 0.991 0 0
Depyrimidination R-HSA-73928 1.265389e-01 0.898 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.232023e-01 0.909 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.841249e-02 1.007 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.329801e-01 0.876 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 1.330813e-01 0.876 0 0
Budding and maturation of HIV virion R-HSA-162588 1.330813e-01 0.876 0 0
Translesion Synthesis by POLH R-HSA-110320 1.341880e-01 0.872 0 0
Glycolysis R-HSA-70171 1.358105e-01 0.867 0 0
mRNA Splicing R-HSA-72172 1.387047e-01 0.858 0 0
Ub-specific processing proteases R-HSA-5689880 1.415512e-01 0.849 0 0
Netrin-1 signaling R-HSA-373752 1.420560e-01 0.848 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.424390e-01 0.846 0 0
Extension of Telomeres R-HSA-180786 1.451802e-01 0.838 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.452595e-01 0.838 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.452595e-01 0.838 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 1.459892e-01 0.836 0 0
SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-3315487 1.459892e-01 0.836 0 0
MPS IIID - Sanfilippo syndrome D R-HSA-2206305 1.459892e-01 0.836 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 1.459892e-01 0.836 0 0
XAV939 stabilizes AXIN R-HSA-5545619 1.459892e-01 0.836 0 0
Loss of Function of SMAD4 in Cancer R-HSA-3304347 1.459892e-01 0.836 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 1.459892e-01 0.836 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.459892e-01 0.836 0 0
Defective SLC12A3 causes Gitelman syndrome (GS) R-HSA-5619087 1.459892e-01 0.836 0 0
SMAD4 MH2 Domain Mutants in Cancer R-HSA-3311021 1.459892e-01 0.836 0 0
TRAF3 deficiency - HSE R-HSA-5602571 1.459892e-01 0.836 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.459892e-01 0.836 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.459892e-01 0.836 0 0
NTRK3 as a dependence receptor R-HSA-9603505 1.459892e-01 0.836 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.462207e-01 0.835 0 0
Interferon alpha/beta signaling R-HSA-909733 1.475654e-01 0.831 0 0
Toll-like Receptor Cascades R-HSA-168898 1.478755e-01 0.830 0 0
Signaling by NOTCH R-HSA-157118 1.487072e-01 0.828 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.501447e-01 0.823 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.501447e-01 0.823 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.501447e-01 0.823 0 0
2-LTR circle formation R-HSA-164843 1.501447e-01 0.823 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.501447e-01 0.823 0 0
Signal attenuation R-HSA-74749 1.501447e-01 0.823 0 0
Signaling by Leptin R-HSA-2586552 1.501447e-01 0.823 0 0
Josephin domain DUBs R-HSA-5689877 1.501447e-01 0.823 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.501447e-01 0.823 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 1.520477e-01 0.818 0 0
FGFR1 mutant receptor activation R-HSA-1839124 1.520477e-01 0.818 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 1.583514e-01 0.800 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 1.585991e-01 0.800 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 1.585991e-01 0.800 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.597408e-01 0.797 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 1.612636e-01 0.792 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.612636e-01 0.792 0 0
NCAM signaling for neurite out-growth R-HSA-375165 1.669291e-01 0.777 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.673580e-01 0.776 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.682201e-01 0.774 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.682201e-01 0.774 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 1.685056e-01 0.773 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 1.685056e-01 0.773 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 1.685056e-01 0.773 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 1.685056e-01 0.773 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.685056e-01 0.773 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.685056e-01 0.773 0 0
Signaling by APC mutants R-HSA-4839744 1.685056e-01 0.773 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 1.685056e-01 0.773 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.685056e-01 0.773 0 0
PECAM1 interactions R-HSA-210990 1.685056e-01 0.773 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.706660e-01 0.768 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 1.712788e-01 0.766 0 0
Assembly Of The HIV Virion R-HSA-175474 1.712788e-01 0.766 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.897575e-01 0.722 0 0
Defective SLC12A1 causes Bartter syndrome 1 (BS1) R-HSA-5619104 1.897575e-01 0.722 0 0
MET interacts with TNS proteins R-HSA-8875513 2.312852e-01 0.636 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 2.312852e-01 0.636 0 0
Signalling to STAT3 R-HSA-198745 2.312852e-01 0.636 0 0
Defective ABCC2 causes DJS R-HSA-5679001 2.312852e-01 0.636 0 0
MET activates PTPN11 R-HSA-8865999 2.312852e-01 0.636 0 0
HCN channels R-HSA-1296061 2.706869e-01 0.568 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.706869e-01 0.568 0 0
NADE modulates death signalling R-HSA-205025 2.706869e-01 0.568 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.706869e-01 0.568 0 0
Nucleotide catabolism defects R-HSA-9735786 2.706869e-01 0.568 0 0
ATP sensitive Potassium channels R-HSA-1296025 2.706869e-01 0.568 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 2.706869e-01 0.568 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.706869e-01 0.568 0 0
IRS activation R-HSA-74713 3.080713e-01 0.511 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 3.080713e-01 0.511 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.872181e-01 0.728 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.872181e-01 0.728 0 0
Signaling by GSK3beta mutants R-HSA-5339716 1.872181e-01 0.728 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 2.061979e-01 0.686 0 0
Polymerase switching R-HSA-69091 2.061979e-01 0.686 0 0
Regulation of IFNG signaling R-HSA-877312 2.061979e-01 0.686 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.061979e-01 0.686 0 0
Leading Strand Synthesis R-HSA-69109 2.061979e-01 0.686 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 2.061979e-01 0.686 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 2.061979e-01 0.686 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 2.061979e-01 0.686 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 2.061979e-01 0.686 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 3.435414e-01 0.464 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 3.435414e-01 0.464 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 3.435414e-01 0.464 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 3.435414e-01 0.464 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 3.435414e-01 0.464 0 0
CD28 dependent Vav1 pathway R-HSA-389359 2.253687e-01 0.647 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.842351e-01 0.735 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.640125e-01 0.578 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 2.640125e-01 0.578 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 2.640125e-01 0.578 0 0
Interleukin receptor SHC signaling R-HSA-912526 1.974391e-01 0.705 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 3.026711e-01 0.519 0 0
Telomere Extension By Telomerase R-HSA-171319 2.662047e-01 0.575 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 3.409567e-01 0.467 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 2.363228e-01 0.626 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 2.363228e-01 0.626 0 0
mRNA 3'-end processing R-HSA-72187 2.113058e-01 0.675 0 0
HIV Transcription Initiation R-HSA-167161 2.589383e-01 0.587 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 2.589383e-01 0.587 0 0
GABA B receptor activation R-HSA-977444 2.704020e-01 0.568 0 0
Activation of GABAB receptors R-HSA-991365 2.704020e-01 0.568 0 0
Dual incision in TC-NER R-HSA-6782135 2.689856e-01 0.570 0 0
Nucleosome assembly R-HSA-774815 3.052584e-01 0.515 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 3.052584e-01 0.515 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.008708e-01 0.522 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 3.173165e-01 0.499 0 0
Formation of a pool of free 40S subunits R-HSA-72689 3.256396e-01 0.487 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.302288e-01 0.481 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.302288e-01 0.481 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 3.190486e-01 0.496 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 3.190486e-01 0.496 0 0
Interleukin-20 family signaling R-HSA-8854691 1.974391e-01 0.705 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 3.190486e-01 0.496 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 1.993339e-01 0.700 0 0
Activation of the pre-replicative complex R-HSA-68962 2.945091e-01 0.531 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.719651e-01 0.765 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 2.493469e-01 0.603 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 2.446611e-01 0.611 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 2.475740e-01 0.606 0 0
G0 and Early G1 R-HSA-1538133 3.229869e-01 0.491 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 1.719651e-01 0.765 0 0
GAB1 signalosome R-HSA-180292 3.409567e-01 0.467 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 3.052584e-01 0.515 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 1.842351e-01 0.735 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 3.218817e-01 0.492 0 0
DNA strand elongation R-HSA-69190 3.229869e-01 0.491 0 0
Peptide chain elongation R-HSA-156902 2.524866e-01 0.598 0 0
Downstream TCR signaling R-HSA-202424 2.683399e-01 0.571 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 2.060107e-01 0.686 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 3.372381e-01 0.472 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.265521e-01 0.645 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 2.589383e-01 0.587 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 3.287563e-01 0.483 0 0
NF-kB is activated and signals survival R-HSA-209560 1.872181e-01 0.728 0 0
Telomere C-strand synthesis initiation R-HSA-174430 2.640125e-01 0.578 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 2.640125e-01 0.578 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 2.662047e-01 0.575 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.989878e-01 0.524 0 0
Insulin receptor signalling cascade R-HSA-74751 1.821447e-01 0.740 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.206401e-01 0.656 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 2.819520e-01 0.550 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.152062e-01 0.667 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 2.833662e-01 0.548 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 2.591219e-01 0.586 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.706869e-01 0.568 0 0
PTK6 Activates STAT3 R-HSA-8849474 3.080713e-01 0.511 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 3.080713e-01 0.511 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 3.435414e-01 0.464 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.719651e-01 0.765 0 0
Defective pyroptosis R-HSA-9710421 2.819520e-01 0.550 0 0
TCR signaling R-HSA-202403 1.979661e-01 0.703 0 0
Prolonged ERK activation events R-HSA-169893 2.833662e-01 0.548 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 2.253687e-01 0.647 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 2.706869e-01 0.568 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 2.706869e-01 0.568 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 3.080713e-01 0.511 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 3.435414e-01 0.464 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 2.446611e-01 0.611 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.833662e-01 0.548 0 0
Eukaryotic Translation Termination R-HSA-72764 3.256396e-01 0.487 0 0
Transcription of the HIV genome R-HSA-167172 2.141104e-01 0.669 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.060107e-01 0.686 0 0
HSF1 activation R-HSA-3371511 1.927245e-01 0.715 0 0
Cellular response to starvation R-HSA-9711097 3.244351e-01 0.489 0 0
Signaling by WNT in cancer R-HSA-4791275 3.229869e-01 0.491 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 1.923595e-01 0.716 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 2.589383e-01 0.587 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 2.312852e-01 0.636 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 2.706869e-01 0.568 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 3.080713e-01 0.511 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.872181e-01 0.728 0 0
Signaling by AXIN mutants R-HSA-4839735 1.872181e-01 0.728 0 0
Signaling by AMER1 mutants R-HSA-4839748 1.872181e-01 0.728 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 2.061979e-01 0.686 0 0
Synthesis of PS R-HSA-1483101 3.435414e-01 0.464 0 0
Ceramide signalling R-HSA-193681 3.435414e-01 0.464 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 3.435414e-01 0.464 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 2.833662e-01 0.548 0 0
Interleukin-7 signaling R-HSA-1266695 2.244770e-01 0.649 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 2.803242e-01 0.552 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 2.223896e-01 0.653 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 2.990246e-01 0.524 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.990246e-01 0.524 0 0
rRNA processing R-HSA-72312 1.817118e-01 0.741 0 0
Gene expression (Transcription) R-HSA-74160 2.359581e-01 0.627 0 0
Oncogene Induced Senescence R-HSA-2559585 1.822465e-01 0.739 0 0
Mismatch Repair R-HSA-5358508 3.409567e-01 0.467 0 0
Polo-like kinase mediated events R-HSA-156711 3.409567e-01 0.467 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 1.719651e-01 0.765 0 0
IRS-mediated signalling R-HSA-112399 2.591219e-01 0.586 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.925956e-01 0.534 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 3.080713e-01 0.511 0 0
Signaling by ALK R-HSA-201556 2.251983e-01 0.647 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 2.627388e-01 0.580 0 0
Atorvastatin ADME R-HSA-9754706 2.833662e-01 0.548 0 0
Cellular response to heat stress R-HSA-3371556 2.836468e-01 0.547 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.379747e-01 0.471 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.706869e-01 0.568 0 0
Muscarinic acetylcholine receptors R-HSA-390648 3.080713e-01 0.511 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 1.845695e-01 0.734 0 0
Regulation of PTEN stability and activity R-HSA-8948751 2.206401e-01 0.656 0 0
G alpha (z) signalling events R-HSA-418597 2.396693e-01 0.620 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 1.845695e-01 0.734 0 0
Death Receptor Signaling R-HSA-73887 2.005453e-01 0.698 0 0
Innate Immune System R-HSA-168249 2.847855e-01 0.545 0 0
Smooth Muscle Contraction R-HSA-445355 2.206401e-01 0.656 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 2.976852e-01 0.526 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.879318e-01 0.726 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 3.295609e-01 0.482 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 2.312852e-01 0.636 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 2.706869e-01 0.568 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 2.061979e-01 0.686 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 3.435414e-01 0.464 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 2.640125e-01 0.578 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.974391e-01 0.705 0 0
Viral Messenger RNA Synthesis R-HSA-168325 2.990246e-01 0.524 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.307726e-01 0.637 0 0
Signal regulatory protein family interactions R-HSA-391160 2.446611e-01 0.611 0 0
Degradation of CDH1 R-HSA-9766229 1.841251e-01 0.735 0 0
Intra-Golgi traffic R-HSA-6811438 2.589383e-01 0.587 0 0
Ion transport by P-type ATPases R-HSA-936837 3.295609e-01 0.482 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.704020e-01 0.568 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.033852e-01 0.692 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.477941e-01 0.606 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.640125e-01 0.578 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 2.382563e-01 0.623 0 0
Adherens junctions interactions R-HSA-418990 1.939683e-01 0.712 0 0
Dopamine receptors R-HSA-390651 2.706869e-01 0.568 0 0
Activation of RAC1 R-HSA-428540 1.872181e-01 0.728 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 3.435414e-01 0.464 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 3.435414e-01 0.464 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 2.253687e-01 0.647 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 2.253687e-01 0.647 0 0
Platelet calcium homeostasis R-HSA-418360 2.803242e-01 0.552 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.858594e-01 0.731 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.763661e-01 0.559 0 0
Protein methylation R-HSA-8876725 2.640125e-01 0.578 0 0
Cleavage of the damaged purine R-HSA-110331 2.033852e-01 0.692 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.372381e-01 0.472 0 0
Integration of provirus R-HSA-162592 1.872181e-01 0.728 0 0
Depurination R-HSA-73927 2.142145e-01 0.669 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 3.080713e-01 0.511 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.080713e-01 0.511 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 3.435414e-01 0.464 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 3.435414e-01 0.464 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.974391e-01 0.705 0 0
Synthesis of PG R-HSA-1483148 3.026711e-01 0.519 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.918713e-01 0.717 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.196229e-01 0.658 0 0
Glucose metabolism R-HSA-70326 2.561594e-01 0.591 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.196229e-01 0.658 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.196229e-01 0.658 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.740925e-01 0.759 0 0
Infectious disease R-HSA-5663205 2.686827e-01 0.571 0 0
Base Excision Repair R-HSA-73884 2.683399e-01 0.571 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 2.300975e-01 0.638 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 2.253687e-01 0.647 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 1.719651e-01 0.765 0 0
Interleukin-37 signaling R-HSA-9008059 2.945091e-01 0.531 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 3.218817e-01 0.492 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.889454e-01 0.539 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 3.026711e-01 0.519 0 0
SARS-CoV Infections R-HSA-9679506 2.149657e-01 0.668 0 0
Growth hormone receptor signaling R-HSA-982772 1.974391e-01 0.705 0 0
Signaling by NOTCH1 R-HSA-1980143 2.829232e-01 0.548 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.889454e-01 0.539 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.889454e-01 0.539 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.889454e-01 0.539 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.889454e-01 0.539 0 0
Apoptotic factor-mediated response R-HSA-111471 3.409567e-01 0.467 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 3.514715e-01 0.454 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 3.514715e-01 0.454 0 0
Effects of PIP2 hydrolysis R-HSA-114508 3.514715e-01 0.454 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.523497e-01 0.453 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 3.598598e-01 0.444 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 3.598598e-01 0.444 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 3.598598e-01 0.444 0 0
Rap1 signalling R-HSA-392517 3.598598e-01 0.444 0 0
The NLRP3 inflammasome R-HSA-844456 3.598598e-01 0.444 0 0
Other interleukin signaling R-HSA-449836 3.598598e-01 0.444 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 3.613613e-01 0.442 0 0
Reproduction R-HSA-1474165 3.626003e-01 0.441 0 0
Signaling by FGFR2 in disease R-HSA-5655253 3.641537e-01 0.439 0 0
Dual Incision in GG-NER R-HSA-5696400 3.656688e-01 0.437 0 0
NOD1/2 Signaling Pathway R-HSA-168638 3.656688e-01 0.437 0 0
ABC-family proteins mediated transport R-HSA-382556 3.676816e-01 0.435 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 3.759481e-01 0.425 0 0
Selenocysteine synthesis R-HSA-2408557 3.761456e-01 0.425 0 0
Interleukin-1 signaling R-HSA-9020702 3.761456e-01 0.425 0 0
Signaling by LTK in cancer R-HSA-9842640 3.771954e-01 0.423 0 0
Erythropoietin activates STAT5 R-HSA-9027283 3.771954e-01 0.423 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 3.771954e-01 0.423 0 0
Defective CHST3 causes SEDCJD R-HSA-3595172 3.771954e-01 0.423 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 3.771954e-01 0.423 0 0
MET Receptor Activation R-HSA-6806942 3.771954e-01 0.423 0 0
Intracellular metabolism of fatty acids regulates insulin secretion R-HSA-434313 3.771954e-01 0.423 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.771954e-01 0.423 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 3.771954e-01 0.423 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.771954e-01 0.423 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 3.771954e-01 0.423 0 0
Negative regulation of MET activity R-HSA-6807004 3.785585e-01 0.422 0 0
Signaling by NODAL R-HSA-1181150 3.785585e-01 0.422 0 0
Signal transduction by L1 R-HSA-445144 3.785585e-01 0.422 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 3.785585e-01 0.422 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 3.798128e-01 0.420 0 0
XBP1(S) activates chaperone genes R-HSA-381038 3.834924e-01 0.416 0 0
PI Metabolism R-HSA-1483255 3.846184e-01 0.415 0 0
Mitochondrial biogenesis R-HSA-1592230 3.849008e-01 0.415 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 3.877226e-01 0.411 0 0
Potential therapeutics for SARS R-HSA-9679191 3.909613e-01 0.408 0 0
Viral mRNA Translation R-HSA-192823 3.930959e-01 0.406 0 0
PRC2 methylates histones and DNA R-HSA-212300 3.938873e-01 0.405 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.938873e-01 0.405 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 3.970242e-01 0.401 0 0
Lagging Strand Synthesis R-HSA-69186 3.970242e-01 0.401 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 3.970242e-01 0.401 0 0
Early Phase of HIV Life Cycle R-HSA-162594 3.970242e-01 0.401 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.006349e-01 0.397 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 4.015502e-01 0.396 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 4.015743e-01 0.396 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 4.048836e-01 0.393 0 0
Interleukin-1 family signaling R-HSA-446652 4.048836e-01 0.393 0 0
Voltage gated Potassium channels R-HSA-1296072 4.078771e-01 0.389 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 4.091259e-01 0.388 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 4.091259e-01 0.388 0 0
TRIF-mediated programmed cell death R-HSA-2562578 4.091259e-01 0.388 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 4.091259e-01 0.388 0 0
Defective CHSY1 causes TPBS R-HSA-3595177 4.091259e-01 0.388 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 4.091259e-01 0.388 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 4.091259e-01 0.388 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 4.091259e-01 0.388 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 4.091259e-01 0.388 0 0
Netrin mediated repulsion signals R-HSA-418886 4.091259e-01 0.388 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 4.091259e-01 0.388 0 0
Regulation of PTEN localization R-HSA-8948747 4.091259e-01 0.388 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 4.091259e-01 0.388 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 4.091259e-01 0.388 0 0
tRNA processing R-HSA-72306 4.095581e-01 0.388 0 0
Keratinization R-HSA-6805567 4.110603e-01 0.386 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.111722e-01 0.386 0 0
Integration of energy metabolism R-HSA-163685 4.141317e-01 0.383 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 4.152315e-01 0.382 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 4.152315e-01 0.382 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 4.152315e-01 0.382 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 4.152315e-01 0.382 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.152315e-01 0.382 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 4.152315e-01 0.382 0 0
Mitochondrial calcium ion transport R-HSA-8949215 4.152315e-01 0.382 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 4.163721e-01 0.381 0 0
Nucleotide Excision Repair R-HSA-5696398 4.185180e-01 0.378 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 4.215068e-01 0.375 0 0
MET promotes cell motility R-HSA-8875878 4.217679e-01 0.375 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 4.217679e-01 0.375 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 4.227970e-01 0.374 0 0
G alpha (q) signalling events R-HSA-416476 4.255091e-01 0.371 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 4.331585e-01 0.363 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 4.331585e-01 0.363 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.344277e-01 0.362 0 0
NRAGE signals death through JNK R-HSA-193648 4.344277e-01 0.362 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 4.344277e-01 0.362 0 0
TNF signaling R-HSA-75893 4.344277e-01 0.362 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.354189e-01 0.361 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.355466e-01 0.361 0 0
Stabilization of p53 R-HSA-69541 4.355466e-01 0.361 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 4.355466e-01 0.361 0 0
IRE1alpha activates chaperones R-HSA-381070 4.388689e-01 0.358 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 4.394213e-01 0.357 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 4.394213e-01 0.357 0 0
phospho-PLA2 pathway R-HSA-111995 4.394213e-01 0.357 0 0
Formation of annular gap junctions R-HSA-196025 4.394213e-01 0.357 0 0
MET receptor recycling R-HSA-8875656 4.394213e-01 0.357 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 4.394213e-01 0.357 0 0
Interleukin-23 signaling R-HSA-9020933 4.394213e-01 0.357 0 0
FGFR1b ligand binding and activation R-HSA-190370 4.394213e-01 0.357 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 4.394213e-01 0.357 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 4.394213e-01 0.357 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 4.394213e-01 0.357 0 0
Adrenoceptors R-HSA-390696 4.394213e-01 0.357 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 4.394213e-01 0.357 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 4.394213e-01 0.357 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 4.394213e-01 0.357 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 4.394213e-01 0.357 0 0
HCMV Late Events R-HSA-9610379 4.397017e-01 0.357 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.416702e-01 0.355 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 4.424128e-01 0.354 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.426418e-01 0.354 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 4.435956e-01 0.353 0 0
Leishmania phagocytosis R-HSA-9664417 4.435956e-01 0.353 0 0
Parasite infection R-HSA-9664407 4.435956e-01 0.353 0 0
Antigen processing-Cross presentation R-HSA-1236975 4.438442e-01 0.353 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 4.466503e-01 0.350 0 0
Muscle contraction R-HSA-397014 4.473986e-01 0.349 0 0
Signaling by Insulin receptor R-HSA-74752 4.480274e-01 0.349 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 4.492007e-01 0.348 0 0
Attenuation phase R-HSA-3371568 4.492007e-01 0.348 0 0
Generation of second messenger molecules R-HSA-202433 4.492007e-01 0.348 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 4.507860e-01 0.346 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 4.507860e-01 0.346 0 0
Syndecan interactions R-HSA-3000170 4.507860e-01 0.346 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 4.577860e-01 0.339 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 4.627189e-01 0.335 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.627189e-01 0.335 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 4.627189e-01 0.335 0 0
Deadenylation of mRNA R-HSA-429947 4.680978e-01 0.330 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 4.680978e-01 0.330 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 4.680978e-01 0.330 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.680978e-01 0.330 0 0
Lipophagy R-HSA-9613354 4.681650e-01 0.330 0 0
Gap junction degradation R-HSA-190873 4.681650e-01 0.330 0 0
ALK mutants bind TKIs R-HSA-9700645 4.681650e-01 0.330 0 0
Unwinding of DNA R-HSA-176974 4.681650e-01 0.330 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 4.681650e-01 0.330 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 4.681650e-01 0.330 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 4.681650e-01 0.330 0 0
MAPK1 (ERK2) activation R-HSA-112411 4.681650e-01 0.330 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 4.681650e-01 0.330 0 0
WNT mediated activation of DVL R-HSA-201688 4.681650e-01 0.330 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 4.681650e-01 0.330 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 4.681650e-01 0.330 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 4.681650e-01 0.330 0 0
Interleukin-1 processing R-HSA-448706 4.681650e-01 0.330 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 4.681650e-01 0.330 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 4.681650e-01 0.330 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 4.681650e-01 0.330 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 4.687992e-01 0.329 0 0
Asparagine N-linked glycosylation R-HSA-446203 4.701524e-01 0.328 0 0
Platelet degranulation R-HSA-114608 4.711268e-01 0.327 0 0
G alpha (12/13) signalling events R-HSA-416482 4.726172e-01 0.325 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 4.752919e-01 0.323 0 0
FCERI mediated MAPK activation R-HSA-2871796 4.772966e-01 0.321 0 0
Inositol phosphate metabolism R-HSA-1483249 4.772966e-01 0.321 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 4.800894e-01 0.319 0 0
GABA receptor activation R-HSA-977443 4.800894e-01 0.319 0 0
RNA Polymerase II Transcription R-HSA-73857 4.811649e-01 0.318 0 0
Co-inhibition by PD-1 R-HSA-389948 4.828818e-01 0.316 0 0
Acyl chain remodelling of PS R-HSA-1482801 4.850799e-01 0.314 0 0
Formation of the nephric duct R-HSA-9830364 4.850799e-01 0.314 0 0
MAP kinase activation R-HSA-450294 4.912845e-01 0.309 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.924601e-01 0.308 0 0
Potassium Channels R-HSA-1296071 4.932518e-01 0.307 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 4.938274e-01 0.306 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 4.946188e-01 0.306 0 0
TCF dependent signaling in response to WNT R-HSA-201681 4.951445e-01 0.305 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.954366e-01 0.305 0 0
PI3K/AKT activation R-HSA-198203 4.954366e-01 0.305 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 4.954366e-01 0.305 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 4.954366e-01 0.305 0 0
MAPK3 (ERK1) activation R-HSA-110056 4.954366e-01 0.305 0 0
Pexophagy R-HSA-9664873 4.954366e-01 0.305 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 4.954366e-01 0.305 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 5.015554e-01 0.300 0 0
MET activates PTK2 signaling R-HSA-8874081 5.017205e-01 0.300 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 5.017205e-01 0.300 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 5.017205e-01 0.300 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 5.017205e-01 0.300 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 5.021553e-01 0.299 0 0
Processing of DNA double-strand break ends R-HSA-5693607 5.022787e-01 0.299 0 0
TBC/RABGAPs R-HSA-8854214 5.023561e-01 0.299 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.023783e-01 0.299 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 5.023783e-01 0.299 0 0
Amine ligand-binding receptors R-HSA-375280 5.152331e-01 0.288 0 0
Parasitic Infection Pathways R-HSA-9824443 5.173175e-01 0.286 0 0
Leishmania infection R-HSA-9658195 5.173175e-01 0.286 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 5.180100e-01 0.286 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 5.180100e-01 0.286 0 0
Signaling by BMP R-HSA-201451 5.180100e-01 0.286 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 5.180100e-01 0.286 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 5.180100e-01 0.286 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 5.180100e-01 0.286 0 0
HATs acetylate histones R-HSA-3214847 5.197915e-01 0.284 0 0
vRNP Assembly R-HSA-192905 5.213113e-01 0.283 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 5.213113e-01 0.283 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 5.213113e-01 0.283 0 0
Bicarbonate transporters R-HSA-425381 5.213113e-01 0.283 0 0
Transport of RCbl within the body R-HSA-9758890 5.213113e-01 0.283 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 5.213113e-01 0.283 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 5.213113e-01 0.283 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 5.213113e-01 0.283 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 5.279297e-01 0.277 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 5.279297e-01 0.277 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 5.279297e-01 0.277 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 5.310090e-01 0.275 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 5.312696e-01 0.275 0 0
HIV elongation arrest and recovery R-HSA-167287 5.339407e-01 0.273 0 0
Pausing and recovery of HIV elongation R-HSA-167290 5.339407e-01 0.273 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 5.339407e-01 0.273 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 5.339407e-01 0.273 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 5.339407e-01 0.273 0 0
Inflammasomes R-HSA-622312 5.339407e-01 0.273 0 0
Regulation of TNFR1 signaling R-HSA-5357905 5.404391e-01 0.267 0 0
Protein-protein interactions at synapses R-HSA-6794362 5.407646e-01 0.267 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.407646e-01 0.267 0 0
Homology Directed Repair R-HSA-5693538 5.423530e-01 0.266 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 5.456266e-01 0.263 0 0
Regulation of endogenous retroelements R-HSA-9842860 5.457702e-01 0.263 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 5.457702e-01 0.263 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 5.458606e-01 0.263 0 0
DS-GAG biosynthesis R-HSA-2022923 5.458606e-01 0.263 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 5.458606e-01 0.263 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 5.458606e-01 0.263 0 0
Plasmalogen biosynthesis R-HSA-75896 5.458606e-01 0.263 0 0
ERKs are inactivated R-HSA-202670 5.458606e-01 0.263 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 5.458606e-01 0.263 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 5.458606e-01 0.263 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 5.458606e-01 0.263 0 0
DNA methylation R-HSA-5334118 5.495066e-01 0.260 0 0
Termination of translesion DNA synthesis R-HSA-5656169 5.495066e-01 0.260 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 5.495066e-01 0.260 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 5.495066e-01 0.260 0 0
DARPP-32 events R-HSA-180024 5.495066e-01 0.260 0 0
Generic Transcription Pathway R-HSA-212436 5.509312e-01 0.259 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.552086e-01 0.256 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.552086e-01 0.256 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 5.647032e-01 0.248 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 5.647032e-01 0.248 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 5.647032e-01 0.248 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 5.665058e-01 0.247 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 5.665058e-01 0.247 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 5.691523e-01 0.245 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 5.691523e-01 0.245 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 5.691523e-01 0.245 0 0
Scavenging by Class F Receptors R-HSA-3000484 5.691523e-01 0.245 0 0
VLDLR internalisation and degradation R-HSA-8866427 5.691523e-01 0.245 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 5.691523e-01 0.245 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 5.691523e-01 0.245 0 0
Disorders of Nervous System Development R-HSA-9697154 5.691523e-01 0.245 0 0
Pervasive developmental disorders R-HSA-9005895 5.691523e-01 0.245 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 5.691523e-01 0.245 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 5.691523e-01 0.245 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 5.691523e-01 0.245 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 5.691523e-01 0.245 0 0
OAS antiviral response R-HSA-8983711 5.691523e-01 0.245 0 0
Unfolded Protein Response (UPR) R-HSA-381119 5.761247e-01 0.239 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 5.767892e-01 0.239 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 5.767892e-01 0.239 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 5.767892e-01 0.239 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 5.795274e-01 0.237 0 0
EGFR downregulation R-HSA-182971 5.795274e-01 0.237 0 0
Trafficking of AMPA receptors R-HSA-399719 5.795274e-01 0.237 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 5.795274e-01 0.237 0 0
ER-Phagosome pathway R-HSA-1236974 5.868165e-01 0.231 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 5.868443e-01 0.231 0 0
Interleukin-17 signaling R-HSA-448424 5.868443e-01 0.231 0 0
Platelet homeostasis R-HSA-418346 5.876066e-01 0.231 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 5.912508e-01 0.228 0 0
Frs2-mediated activation R-HSA-170968 5.912508e-01 0.228 0 0
Diseases of nucleotide metabolism R-HSA-9735804 5.912508e-01 0.228 0 0
FGFR1c ligand binding and activation R-HSA-190373 5.912508e-01 0.228 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 5.912508e-01 0.228 0 0
Inwardly rectifying K+ channels R-HSA-1296065 5.939774e-01 0.226 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.968023e-01 0.224 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 5.999961e-01 0.222 0 0
HSF1-dependent transactivation R-HSA-3371571 5.999961e-01 0.222 0 0
Meiotic recombination R-HSA-912446 5.999961e-01 0.222 0 0
Signaling by WNT R-HSA-195721 6.049819e-01 0.218 0 0
Nuclear RNA decay R-HSA-9930044 6.080527e-01 0.216 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 6.080527e-01 0.216 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 6.080527e-01 0.216 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 6.080527e-01 0.216 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 6.080527e-01 0.216 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 6.080527e-01 0.216 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 6.080527e-01 0.216 0 0
G-protein beta:gamma signalling R-HSA-397795 6.080527e-01 0.216 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 6.112814e-01 0.214 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 6.112814e-01 0.214 0 0
DNA Replication Pre-Initiation R-HSA-69002 6.117243e-01 0.213 0 0
Removal of the Flap Intermediate R-HSA-69166 6.122171e-01 0.213 0 0
Retrograde neurotrophin signalling R-HSA-177504 6.122171e-01 0.213 0 0
NRIF signals cell death from the nucleus R-HSA-205043 6.122171e-01 0.213 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 6.122171e-01 0.213 0 0
Hydrolysis of LPC R-HSA-1483115 6.122171e-01 0.213 0 0
HDL assembly R-HSA-8963896 6.122171e-01 0.213 0 0
Acyl chain remodeling of CL R-HSA-1482798 6.122171e-01 0.213 0 0
Zinc transporters R-HSA-435354 6.122171e-01 0.213 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 6.162820e-01 0.210 0 0
Selenoamino acid metabolism R-HSA-2408522 6.182039e-01 0.209 0 0
Striated Muscle Contraction R-HSA-390522 6.217536e-01 0.206 0 0
Heme degradation R-HSA-189483 6.217536e-01 0.206 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 6.223513e-01 0.206 0 0
Signaling by NOTCH4 R-HSA-9013694 6.257988e-01 0.204 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 6.321092e-01 0.199 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 6.321092e-01 0.199 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 6.321092e-01 0.199 0 0
Processive synthesis on the lagging strand R-HSA-69183 6.321092e-01 0.199 0 0
Translesion synthesis by REV1 R-HSA-110312 6.321092e-01 0.199 0 0
Protein lipoylation R-HSA-9857492 6.321092e-01 0.199 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 6.321092e-01 0.199 0 0
Signaling by Activin R-HSA-1502540 6.321092e-01 0.199 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 6.321092e-01 0.199 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 6.321092e-01 0.199 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 6.321092e-01 0.199 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 6.321092e-01 0.199 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 6.350815e-01 0.197 0 0
Signaling by NOTCH2 R-HSA-1980145 6.350815e-01 0.197 0 0
eNOS activation R-HSA-203615 6.350815e-01 0.197 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 6.350815e-01 0.197 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 6.350815e-01 0.197 0 0
Signal amplification R-HSA-392518 6.350815e-01 0.197 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 6.351643e-01 0.197 0 0
SLC transporter disorders R-HSA-5619102 6.372540e-01 0.196 0 0
Signaling by NOTCH3 R-HSA-9012852 6.438379e-01 0.191 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.443768e-01 0.191 0 0
S Phase R-HSA-69242 6.448371e-01 0.191 0 0
Disorders of transmembrane transporters R-HSA-5619115 6.475227e-01 0.189 0 0
Regulation of Apoptosis R-HSA-169911 6.480386e-01 0.188 0 0
Acyl chain remodelling of PE R-HSA-1482839 6.480386e-01 0.188 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 6.480386e-01 0.188 0 0
PERK regulates gene expression R-HSA-381042 6.480386e-01 0.188 0 0
Translesion synthesis by POLI R-HSA-5656121 6.509820e-01 0.186 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 6.509820e-01 0.186 0 0
Killing mechanisms R-HSA-9664420 6.509820e-01 0.186 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 6.509820e-01 0.186 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 6.509820e-01 0.186 0 0
Differentiation of T cells R-HSA-9945266 6.509820e-01 0.186 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 6.509820e-01 0.186 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 6.509820e-01 0.186 0 0
Negative regulation of FLT3 R-HSA-9706369 6.509820e-01 0.186 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 6.509820e-01 0.186 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 6.509820e-01 0.186 0 0
Activation of SMO R-HSA-5635838 6.509820e-01 0.186 0 0
Attachment and Entry R-HSA-9678110 6.509820e-01 0.186 0 0
Ion homeostasis R-HSA-5578775 6.542522e-01 0.184 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 6.606279e-01 0.180 0 0
GPVI-mediated activation cascade R-HSA-114604 6.606279e-01 0.180 0 0
RUNX2 regulates bone development R-HSA-8941326 6.606279e-01 0.180 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 6.606279e-01 0.180 0 0
Circadian clock R-HSA-9909396 6.606809e-01 0.180 0 0
RNA Polymerase I Transcription R-HSA-73864 6.623371e-01 0.179 0 0
ABC transporter disorders R-HSA-5619084 6.623371e-01 0.179 0 0
PCP/CE pathway R-HSA-4086400 6.623371e-01 0.179 0 0
Synthesis of PA R-HSA-1483166 6.644463e-01 0.178 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 6.688877e-01 0.175 0 0
Translesion synthesis by POLK R-HSA-5655862 6.688877e-01 0.175 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 6.688877e-01 0.175 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 6.688877e-01 0.175 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 6.688877e-01 0.175 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 6.688877e-01 0.175 0 0
Glycine degradation R-HSA-6783984 6.688877e-01 0.175 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 6.688877e-01 0.175 0 0
Scavenging by Class B Receptors R-HSA-3000471 6.688877e-01 0.175 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 6.688877e-01 0.175 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 6.688877e-01 0.175 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 6.688877e-01 0.175 0 0
Disorders of Developmental Biology R-HSA-9675151 6.688877e-01 0.175 0 0
Galactose catabolism R-HSA-70370 6.688877e-01 0.175 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 6.688877e-01 0.175 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.707710e-01 0.173 0 0
Sensory processing of sound R-HSA-9659379 6.710828e-01 0.173 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 6.728530e-01 0.172 0 0
Degradation of AXIN R-HSA-4641257 6.728530e-01 0.172 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 6.728530e-01 0.172 0 0
Degradation of DVL R-HSA-4641258 6.728530e-01 0.172 0 0
Metabolism of folate and pterines R-HSA-196757 6.728530e-01 0.172 0 0
DNA Replication R-HSA-69306 6.766972e-01 0.170 0 0
Post-translational protein phosphorylation R-HSA-8957275 6.785163e-01 0.168 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 6.841736e-01 0.165 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 6.847181e-01 0.164 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 6.858758e-01 0.164 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 6.858758e-01 0.164 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 6.858758e-01 0.164 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 6.858758e-01 0.164 0 0
Rab regulation of trafficking R-HSA-9007101 6.860998e-01 0.164 0 0
PPARA activates gene expression R-HSA-1989781 6.889381e-01 0.162 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 6.962280e-01 0.157 0 0
Pentose phosphate pathway R-HSA-71336 6.962280e-01 0.157 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 6.962280e-01 0.157 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 6.963744e-01 0.157 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 7.008839e-01 0.154 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 7.019933e-01 0.154 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 7.019933e-01 0.154 0 0
FGFR1 ligand binding and activation R-HSA-190242 7.019933e-01 0.154 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 7.019933e-01 0.154 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 7.019933e-01 0.154 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.030226e-01 0.153 0 0
Aquaporin-mediated transport R-HSA-445717 7.030226e-01 0.153 0 0
Cytoprotection by HMOX1 R-HSA-9707564 7.044887e-01 0.152 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 7.073879e-01 0.150 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 7.073879e-01 0.150 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 7.073879e-01 0.150 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 7.073879e-01 0.150 0 0
HIV Transcription Elongation R-HSA-167169 7.073879e-01 0.150 0 0
Heme signaling R-HSA-9707616 7.121200e-01 0.147 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.124449e-01 0.147 0 0
Interferon gamma signaling R-HSA-877300 7.125307e-01 0.147 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 7.172848e-01 0.144 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 7.172848e-01 0.144 0 0
Germ layer formation at gastrulation R-HSA-9754189 7.172848e-01 0.144 0 0
Pyrimidine biosynthesis R-HSA-500753 7.172848e-01 0.144 0 0
Regulation of signaling by CBL R-HSA-912631 7.172848e-01 0.144 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 7.172848e-01 0.144 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 7.172848e-01 0.144 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 7.182033e-01 0.144 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 7.182033e-01 0.144 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 7.182033e-01 0.144 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.196366e-01 0.143 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 7.210010e-01 0.142 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 7.278841e-01 0.138 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 7.286803e-01 0.137 0 0
RSV-host interactions R-HSA-9833110 7.292785e-01 0.137 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 7.317925e-01 0.136 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 7.317925e-01 0.136 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 7.317925e-01 0.136 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 7.317925e-01 0.136 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 7.317925e-01 0.136 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 7.317925e-01 0.136 0 0
Formation of definitive endoderm R-HSA-9823730 7.317925e-01 0.136 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 7.317925e-01 0.136 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 7.317925e-01 0.136 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 7.317925e-01 0.136 0 0
Acyl chain remodelling of PI R-HSA-1482922 7.317925e-01 0.136 0 0
Nephrin family interactions R-HSA-373753 7.317925e-01 0.136 0 0
Keratan sulfate degradation R-HSA-2022857 7.317925e-01 0.136 0 0
Glycogen synthesis R-HSA-3322077 7.317925e-01 0.136 0 0
Cellular response to hypoxia R-HSA-1234174 7.381207e-01 0.132 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 7.388250e-01 0.131 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 7.388250e-01 0.131 0 0
G1/S Transition R-HSA-69206 7.445129e-01 0.128 0 0
G-protein activation R-HSA-202040 7.455565e-01 0.128 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 7.455565e-01 0.128 0 0
ERK/MAPK targets R-HSA-198753 7.455565e-01 0.128 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 7.455565e-01 0.128 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 7.455565e-01 0.128 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 7.455565e-01 0.128 0 0
Acyl chain remodelling of PG R-HSA-1482925 7.455565e-01 0.128 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 7.486440e-01 0.126 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 7.486440e-01 0.126 0 0
GPCR downstream signalling R-HSA-388396 7.491655e-01 0.125 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 7.543974e-01 0.122 0 0
Proteasome assembly R-HSA-9907900 7.581440e-01 0.120 0 0
RMTs methylate histone arginines R-HSA-3214858 7.581440e-01 0.120 0 0
Cyclin D associated events in G1 R-HSA-69231 7.581440e-01 0.120 0 0
G1 Phase R-HSA-69236 7.581440e-01 0.120 0 0
CS-GAG biosynthesis R-HSA-2022870 7.586150e-01 0.120 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 7.586150e-01 0.120 0 0
Attachment and Entry R-HSA-9694614 7.586150e-01 0.120 0 0
Ribavirin ADME R-HSA-9755088 7.586150e-01 0.120 0 0
Fanconi Anemia Pathway R-HSA-6783310 7.673318e-01 0.115 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 7.673318e-01 0.115 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 7.673318e-01 0.115 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 7.673318e-01 0.115 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 7.673318e-01 0.115 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 7.710041e-01 0.113 0 0
FGFR2 alternative splicing R-HSA-6803529 7.710041e-01 0.113 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 7.710041e-01 0.113 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.710041e-01 0.113 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 7.710041e-01 0.113 0 0
LDL clearance R-HSA-8964038 7.710041e-01 0.113 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.710041e-01 0.113 0 0
Ethanol oxidation R-HSA-71384 7.710041e-01 0.113 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 7.710041e-01 0.113 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 7.762144e-01 0.110 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 7.762144e-01 0.110 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 7.762144e-01 0.110 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 7.762144e-01 0.110 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 7.762144e-01 0.110 0 0
Diseases of DNA repair R-HSA-9675135 7.762144e-01 0.110 0 0
Signaling by TGFBR3 R-HSA-9839373 7.762144e-01 0.110 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 7.772735e-01 0.109 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 7.772735e-01 0.109 0 0
G alpha (s) signalling events R-HSA-418555 7.808221e-01 0.107 0 0
Formation of the ureteric bud R-HSA-9830674 7.827580e-01 0.106 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 7.827580e-01 0.106 0 0
Organic anion transport by SLCO transporters R-HSA-879518 7.827580e-01 0.106 0 0
Biosynthesis of maresins R-HSA-9018682 7.827580e-01 0.106 0 0
Cardiac conduction R-HSA-5576891 7.842316e-01 0.106 0 0
Hedgehog 'on' state R-HSA-5632684 7.844992e-01 0.105 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 7.847990e-01 0.105 0 0
Assembly of the pre-replicative complex R-HSA-68867 7.897088e-01 0.103 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 7.915300e-01 0.102 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 7.915300e-01 0.102 0 0
Gluconeogenesis R-HSA-70263 7.930927e-01 0.101 0 0
NGF-stimulated transcription R-HSA-9031628 7.930927e-01 0.101 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 7.939092e-01 0.100 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 7.939092e-01 0.100 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.939092e-01 0.100 0 0
TNFs bind their physiological receptors R-HSA-5669034 7.939092e-01 0.100 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.939092e-01 0.100 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.968765e-01 0.099 0 0
Ca2+ pathway R-HSA-4086398 7.983688e-01 0.098 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.016551e-01 0.096 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 8.044887e-01 0.094 0 0
G protein gated Potassium channels R-HSA-1296059 8.044887e-01 0.094 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 8.044887e-01 0.094 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 8.044887e-01 0.094 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 8.044887e-01 0.094 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 8.044887e-01 0.094 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 8.044887e-01 0.094 0 0
TGFBR3 expression R-HSA-9839394 8.044887e-01 0.094 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 8.044887e-01 0.094 0 0
Laminin interactions R-HSA-3000157 8.044887e-01 0.094 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 8.044887e-01 0.094 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 8.044887e-01 0.094 0 0
Azathioprine ADME R-HSA-9748787 8.088364e-01 0.092 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.114836e-01 0.091 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 8.143958e-01 0.089 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 8.145258e-01 0.089 0 0
Myogenesis R-HSA-525793 8.145258e-01 0.089 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 8.145258e-01 0.089 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 8.145258e-01 0.089 0 0
Metalloprotease DUBs R-HSA-5689901 8.145258e-01 0.089 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 8.145258e-01 0.089 0 0
TRP channels R-HSA-3295583 8.145258e-01 0.089 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 8.145258e-01 0.089 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 8.145258e-01 0.089 0 0
Hedgehog ligand biogenesis R-HSA-5358346 8.163010e-01 0.088 0 0
UCH proteinases R-HSA-5689603 8.177661e-01 0.087 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 8.235036e-01 0.084 0 0
Neurexins and neuroligins R-HSA-6794361 8.235036e-01 0.084 0 0
Orc1 removal from chromatin R-HSA-68949 8.235036e-01 0.084 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.235036e-01 0.084 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 8.235036e-01 0.084 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 8.235036e-01 0.084 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 8.238697e-01 0.084 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 8.240481e-01 0.084 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 8.240481e-01 0.084 0 0
Cristae formation R-HSA-8949613 8.240481e-01 0.084 0 0
Maturation of hRSV A proteins R-HSA-9828806 8.240481e-01 0.084 0 0
Signaling by TGFB family members R-HSA-9006936 8.257823e-01 0.083 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 8.304515e-01 0.081 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 8.304515e-01 0.081 0 0
Nucleotide biosynthesis R-HSA-8956320 8.304515e-01 0.081 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 8.330821e-01 0.079 0 0
Prednisone ADME R-HSA-9757110 8.330821e-01 0.079 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 8.355541e-01 0.078 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 8.416528e-01 0.075 0 0
Regulation of gene expression in beta cells R-HSA-210745 8.416528e-01 0.075 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 8.436118e-01 0.074 0 0
Paracetamol ADME R-HSA-9753281 8.436118e-01 0.074 0 0
Phospholipid metabolism R-HSA-1483257 8.444121e-01 0.073 0 0
Amyloid fiber formation R-HSA-977225 8.465647e-01 0.072 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.497838e-01 0.071 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 8.497838e-01 0.071 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 8.497838e-01 0.071 0 0
Mucopolysaccharidoses R-HSA-2206281 8.497838e-01 0.071 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 8.498383e-01 0.071 0 0
Ion channel transport R-HSA-983712 8.546156e-01 0.068 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 8.574979e-01 0.067 0 0
Cargo concentration in the ER R-HSA-5694530 8.574979e-01 0.067 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.574979e-01 0.067 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.585729e-01 0.066 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.585729e-01 0.066 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 8.616185e-01 0.065 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 8.616185e-01 0.065 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 8.628624e-01 0.064 0 0
Diseases of mitotic cell cycle R-HSA-9675126 8.648162e-01 0.063 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.648162e-01 0.063 0 0
Post-translational protein modification R-HSA-597592 8.671352e-01 0.062 0 0
Peroxisomal protein import R-HSA-9033241 8.671858e-01 0.062 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 8.713266e-01 0.060 0 0
Synthesis of DNA R-HSA-69239 8.714192e-01 0.060 0 0
Defective B3GALTL causes PpS R-HSA-5083635 8.717591e-01 0.060 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 8.717591e-01 0.060 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 8.717591e-01 0.060 0 0
Regulation of necroptotic cell death R-HSA-5675482 8.717591e-01 0.060 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 8.717591e-01 0.060 0 0
Cardiogenesis R-HSA-9733709 8.717591e-01 0.060 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 8.717591e-01 0.060 0 0
RAB geranylgeranylation R-HSA-8873719 8.725468e-01 0.059 0 0
tRNA Aminoacylation R-HSA-379724 8.725468e-01 0.059 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 8.725468e-01 0.059 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 8.725468e-01 0.059 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 8.758332e-01 0.058 0 0
Leishmania parasite growth and survival R-HSA-9664433 8.774632e-01 0.057 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 8.774632e-01 0.057 0 0
Collagen degradation R-HSA-1442490 8.777079e-01 0.057 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 8.783459e-01 0.056 0 0
Resolution of D-Loop Structures R-HSA-5693537 8.783459e-01 0.056 0 0
CS/DS degradation R-HSA-2024101 8.783459e-01 0.056 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.783459e-01 0.056 0 0
Vpu mediated degradation of CD4 R-HSA-180534 8.783459e-01 0.056 0 0
Glutamate and glutamine metabolism R-HSA-8964539 8.783459e-01 0.056 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.783459e-01 0.056 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.820300e-01 0.055 0 0
Mitochondrial protein import R-HSA-1268020 8.826756e-01 0.054 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 8.845947e-01 0.053 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.845947e-01 0.053 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.845947e-01 0.053 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 8.845947e-01 0.053 0 0
Hyaluronan metabolism R-HSA-2142845 8.845947e-01 0.053 0 0
Neddylation R-HSA-8951664 8.863088e-01 0.052 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 8.874560e-01 0.052 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 8.905229e-01 0.050 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 8.905229e-01 0.050 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.905229e-01 0.050 0 0
RNA Polymerase III Transcription R-HSA-74158 8.961469e-01 0.048 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 8.961469e-01 0.048 0 0
Glycosphingolipid transport R-HSA-9845576 8.961469e-01 0.048 0 0
G1/S-Specific Transcription R-HSA-69205 8.961469e-01 0.048 0 0
Triglyceride catabolism R-HSA-163560 8.961469e-01 0.048 0 0
O-glycosylation of TSR domain-containing proteins R-HSA-5173214 9.014823e-01 0.045 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.014823e-01 0.045 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.014823e-01 0.045 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.014823e-01 0.045 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.014823e-01 0.045 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 9.014823e-01 0.045 0 0
Collagen chain trimerization R-HSA-8948216 9.014823e-01 0.045 0 0
Kidney development R-HSA-9830369 9.048258e-01 0.043 0 0
G alpha (i) signalling events R-HSA-418594 9.051580e-01 0.043 0 0
Translation R-HSA-72766 9.053543e-01 0.043 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 9.065439e-01 0.043 0 0
Purine salvage R-HSA-74217 9.065439e-01 0.043 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.065439e-01 0.043 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.065439e-01 0.043 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.072237e-01 0.042 0 0
Signaling by GPCR R-HSA-372790 9.086838e-01 0.042 0 0
Collagen formation R-HSA-1474290 9.104758e-01 0.041 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.113458e-01 0.040 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.113458e-01 0.040 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.113458e-01 0.040 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.159012e-01 0.038 0 0
Glycogen metabolism R-HSA-8982491 9.159012e-01 0.038 0 0
COPII-mediated vesicle transport R-HSA-204005 9.161733e-01 0.038 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 9.161733e-01 0.038 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 9.196646e-01 0.036 0 0
Regulation of mitotic cell cycle R-HSA-453276 9.196646e-01 0.036 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.196646e-01 0.036 0 0
Metabolism of cofactors R-HSA-8978934 9.196646e-01 0.036 0 0
Metabolism of porphyrins R-HSA-189445 9.196646e-01 0.036 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.202228e-01 0.036 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.202228e-01 0.036 0 0
Maturation of spike protein R-HSA-9694548 9.202228e-01 0.036 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.202228e-01 0.036 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.243226e-01 0.034 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.243226e-01 0.034 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.243226e-01 0.034 0 0
Regulation of insulin secretion R-HSA-422356 9.256887e-01 0.034 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.262407e-01 0.033 0 0
Aspirin ADME R-HSA-9749641 9.262407e-01 0.033 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.275573e-01 0.033 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.282119e-01 0.032 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.293350e-01 0.032 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.323064e-01 0.030 0 0
Protein ubiquitination R-HSA-8852135 9.323064e-01 0.030 0 0
Surfactant metabolism R-HSA-5683826 9.354018e-01 0.029 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.354018e-01 0.029 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.354018e-01 0.029 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.387223e-01 0.027 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 9.387223e-01 0.027 0 0
Somitogenesis R-HSA-9824272 9.387223e-01 0.027 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.405267e-01 0.027 0 0
Interleukin-10 signaling R-HSA-6783783 9.405267e-01 0.027 0 0
Integrin cell surface interactions R-HSA-216083 9.405267e-01 0.027 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.418723e-01 0.026 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.418723e-01 0.026 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.448606e-01 0.025 0 0
Synthesis of PC R-HSA-1483191 9.448606e-01 0.025 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.448606e-01 0.025 0 0
Protein localization R-HSA-9609507 9.457449e-01 0.024 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 9.476954e-01 0.023 0 0
Metal ion SLC transporters R-HSA-425410 9.476954e-01 0.023 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.503847e-01 0.022 0 0
Keratan sulfate/keratin metabolism R-HSA-1638074 9.503847e-01 0.022 0 0
Stimuli-sensing channels R-HSA-2672351 9.511647e-01 0.022 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.521583e-01 0.021 0 0
PI3K Cascade R-HSA-109704 9.529358e-01 0.021 0 0
Complex IV assembly R-HSA-9864848 9.553559e-01 0.020 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.553559e-01 0.020 0 0
The phototransduction cascade R-HSA-2514856 9.553559e-01 0.020 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.576517e-01 0.019 0 0
Peptide ligand-binding receptors R-HSA-375276 9.582395e-01 0.019 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.598296e-01 0.018 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.598296e-01 0.018 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.618956e-01 0.017 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.638555e-01 0.016 0 0
Dectin-2 family R-HSA-5621480 9.674783e-01 0.014 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.691513e-01 0.014 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.705766e-01 0.013 0 0
Triglyceride metabolism R-HSA-8979227 9.707384e-01 0.013 0 0
Regulation of beta-cell development R-HSA-186712 9.707384e-01 0.013 0 0
FCGR activation R-HSA-2029481 9.718613e-01 0.012 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.718613e-01 0.012 0 0
Metabolism of polyamines R-HSA-351202 9.722439e-01 0.012 0 0
Nucleotide salvage R-HSA-8956321 9.736720e-01 0.012 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.736720e-01 0.012 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.750267e-01 0.011 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.758368e-01 0.011 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.764795e-01 0.010 0 0
Xenobiotics R-HSA-211981 9.775309e-01 0.010 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.816326e-01 0.008 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.818117e-01 0.008 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.836362e-01 0.007 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.840715e-01 0.007 0 0
Retinoid metabolism and transport R-HSA-975634 9.844787e-01 0.007 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 9.844787e-01 0.007 0 0
Purine catabolism R-HSA-74259 9.852778e-01 0.006 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.852778e-01 0.006 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.860359e-01 0.006 0 0
Iron uptake and transport R-HSA-917937 9.874370e-01 0.005 0 0
Translation of Structural Proteins R-HSA-9694635 9.886977e-01 0.005 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.887539e-01 0.005 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.892798e-01 0.005 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.903342e-01 0.004 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.908526e-01 0.004 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.908526e-01 0.004 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.913771e-01 0.004 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.921949e-01 0.003 0 0
MITF-M-dependent gene expression R-HSA-9856651 9.930981e-01 0.003 0 0
Pyruvate metabolism R-HSA-70268 9.936836e-01 0.003 0 0
Diseases of glycosylation R-HSA-3781865 9.939629e-01 0.003 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.940091e-01 0.003 0 0
Neurotransmitter release cycle R-HSA-112310 9.946108e-01 0.002 0 0
Drug ADME R-HSA-9748784 9.949573e-01 0.002 0 0
Extracellular matrix organization R-HSA-1474244 9.949993e-01 0.002 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.954021e-01 0.002 0 0
Mitochondrial protein degradation R-HSA-9837999 9.958640e-01 0.002 0 0
Metabolism of proteins R-HSA-392499 9.964847e-01 0.002 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.969897e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.980997e-01 0.001 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 9.982159e-01 0.001 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.984060e-01 0.001 0 0
Visual phototransduction R-HSA-2187338 9.984106e-01 0.001 0 0
Antimicrobial peptides R-HSA-6803157 9.984883e-01 0.001 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.984922e-01 0.001 0 0
Gastrulation R-HSA-9758941 9.985552e-01 0.001 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.986225e-01 0.001 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.989856e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.991237e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.992804e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.993203e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.994847e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.995037e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.995767e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.997081e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.997988e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.998753e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.998892e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999308e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.999438e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999464e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999703e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999806e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999848e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999875e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999935e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999961e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999994e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
Cell Cycle, Mitotic R-HSA-69278 1.110223e-16 15.955 0 0
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Metabolism of RNA R-HSA-8953854 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.220446e-16 15.654 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.220446e-16 15.654 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 3.330669e-16 15.477 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.332268e-15 14.875 0 0
Signaling by ROBO receptors R-HSA-376176 1.476597e-14 13.831 0 0
Cell-Cell communication R-HSA-1500931 2.831069e-14 13.548 0 0
Eukaryotic Translation Elongation R-HSA-156842 3.985701e-14 13.399 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.044720e-13 12.981 0 0
Mitotic Anaphase R-HSA-68882 1.038059e-13 12.984 0 0
Influenza Infection R-HSA-168255 1.190159e-13 12.924 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.274536e-13 12.895 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.910694e-13 12.719 0 0
Translation initiation complex formation R-HSA-72649 2.771117e-13 12.557 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 3.395062e-13 12.469 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 4.239942e-13 12.373 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.707657e-13 12.244 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 6.676881e-13 12.175 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 8.114620e-13 12.091 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 8.114620e-13 12.091 0 0
Peptide chain elongation R-HSA-156902 1.633693e-12 11.787 0 0
HSF1-dependent transactivation R-HSA-3371571 1.664224e-12 11.779 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.707967e-12 11.768 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.388756e-12 11.622 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.235856e-12 11.490 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 6.460166e-12 11.190 0 0
Cell junction organization R-HSA-446728 1.202927e-11 10.920 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.414158e-11 10.850 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 1.547329e-11 10.810 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.949607e-11 10.710 0 0
Ribosome-associated quality control R-HSA-9948299 2.320177e-11 10.634 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 2.581846e-11 10.588 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 2.760558e-11 10.559 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 2.873213e-11 10.542 0 0
Apoptosis R-HSA-109581 2.972345e-11 10.527 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 5.919543e-11 10.228 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 9.130963e-11 10.039 0 0
Eukaryotic Translation Termination R-HSA-72764 8.917123e-11 10.050 0 0
Attenuation phase R-HSA-3371568 9.428502e-11 10.026 0 0
Separation of Sister Chromatids R-HSA-2467813 1.239301e-10 9.907 0 0
Mitotic Prometaphase R-HSA-68877 3.092981e-10 9.510 0 0
Apoptotic execution phase R-HSA-75153 4.114131e-10 9.386 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.547500e-10 9.342 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 5.152633e-10 9.288 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 7.046435e-10 9.152 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.209459e-09 8.917 0 0
Programmed Cell Death R-HSA-5357801 1.203730e-09 8.919 0 0
SARS-CoV-1 Infection R-HSA-9678108 1.246614e-09 8.904 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.292609e-09 8.889 0 0
Signal Transduction R-HSA-162582 1.319754e-09 8.880 0 0
Selenocysteine synthesis R-HSA-2408557 1.419497e-09 8.848 0 0
HSF1 activation R-HSA-3371511 1.757492e-09 8.755 0 0
Aggrephagy R-HSA-9646399 2.106510e-09 8.676 0 0
Viral mRNA Translation R-HSA-192823 2.326390e-09 8.633 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.881639e-09 8.540 0 0
Selective autophagy R-HSA-9663891 3.065777e-09 8.513 0 0
L1CAM interactions R-HSA-373760 3.663936e-09 8.436 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 4.067545e-09 8.391 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.530612e-09 8.257 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.530612e-09 8.257 0 0
rRNA processing R-HSA-72312 6.744950e-09 8.171 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 7.453742e-09 8.128 0 0
Adherens junctions interactions R-HSA-418990 9.667661e-09 8.015 0 0
Recycling pathway of L1 R-HSA-437239 1.079560e-08 7.967 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.534980e-08 7.814 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.858497e-08 7.731 0 0
Cell-cell junction organization R-HSA-421270 2.103244e-08 7.677 0 0
G2/M Transition R-HSA-69275 2.036291e-08 7.691 0 0
Post NMDA receptor activation events R-HSA-438064 2.404514e-08 7.619 0 0
Mitotic G2-G2/M phases R-HSA-453274 2.807283e-08 7.552 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.093281e-08 7.510 0 0
SARS-CoV-2-host interactions R-HSA-9705683 4.211593e-08 7.376 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 4.216339e-08 7.375 0 0
mRNA Splicing R-HSA-72172 7.172444e-08 7.144 0 0
Cellular response to starvation R-HSA-9711097 7.791288e-08 7.108 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 9.679293e-08 7.014 0 0
PKR-mediated signaling R-HSA-9833482 9.912018e-08 7.004 0 0
Interleukin-12 signaling R-HSA-9020591 1.137510e-07 6.944 0 0
Cell Cycle Checkpoints R-HSA-69620 1.139327e-07 6.943 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.463885e-07 6.834 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 1.574564e-07 6.803 0 0
Mitotic Prophase R-HSA-68875 1.736361e-07 6.760 0 0
Signaling by ERBB2 R-HSA-1227986 1.812412e-07 6.742 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.148825e-07 6.668 0 0
Viral Infection Pathways R-HSA-9824446 2.213329e-07 6.655 0 0
Transport of connexons to the plasma membrane R-HSA-190872 2.742120e-07 6.562 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.770004e-07 6.558 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.787500e-07 6.422 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 4.093614e-07 6.388 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 4.843961e-07 6.315 0 0
Chromatin organization R-HSA-4839726 6.666494e-07 6.176 0 0
Interleukin-12 family signaling R-HSA-447115 6.392085e-07 6.194 0 0
EPH-Ephrin signaling R-HSA-2682334 8.172310e-07 6.088 0 0
Interferon Signaling R-HSA-913531 8.676897e-07 6.062 0 0
Oncogenic MAPK signaling R-HSA-6802957 9.483321e-07 6.023 0 0
Cell-extracellular matrix interactions R-HSA-446353 9.951921e-07 6.002 0 0
Developmental Biology R-HSA-1266738 1.143473e-06 5.942 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.245444e-06 5.905 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.245444e-06 5.905 0 0
Neutrophil degranulation R-HSA-6798695 1.353834e-06 5.868 0 0
Signaling by RAS mutants R-HSA-6802949 1.583507e-06 5.800 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.583507e-06 5.800 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.583507e-06 5.800 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.583507e-06 5.800 0 0
Macroautophagy R-HSA-1632852 1.799610e-06 5.745 0 0
Chromatin modifying enzymes R-HSA-3247509 1.828866e-06 5.738 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.837388e-06 5.736 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.873103e-06 5.727 0 0
Kinesins R-HSA-983189 1.952139e-06 5.709 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.210268e-06 5.656 0 0
Host Interactions of HIV factors R-HSA-162909 2.245982e-06 5.649 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 2.562159e-06 5.591 0 0
Regulation of CDH1 Function R-HSA-9764561 2.884520e-06 5.540 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.907599e-06 5.536 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.575877e-06 5.447 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 3.855214e-06 5.414 0 0
Autophagy R-HSA-9612973 3.827780e-06 5.417 0 0
Cytokine Signaling in Immune system R-HSA-1280215 4.108025e-06 5.386 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.261970e-06 5.370 0 0
Ub-specific processing proteases R-HSA-5689880 4.501991e-06 5.347 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 4.533003e-06 5.344 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 4.607821e-06 5.337 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 4.828372e-06 5.316 0 0
Translation R-HSA-72766 5.616944e-06 5.250 0 0
Selenoamino acid metabolism R-HSA-2408522 5.363226e-06 5.271 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 6.053614e-06 5.218 0 0
HIV Infection R-HSA-162906 6.392272e-06 5.194 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 6.847355e-06 5.164 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.125020e-06 5.147 0 0
Nuclear Envelope Breakdown R-HSA-2980766 8.985482e-06 5.046 0 0
G2/M Checkpoints R-HSA-69481 1.002940e-05 4.999 0 0
RMTs methylate histone arginines R-HSA-3214858 1.050871e-05 4.978 0 0
Gap junction trafficking R-HSA-190828 1.050871e-05 4.978 0 0
PECAM1 interactions R-HSA-210990 1.197192e-05 4.922 0 0
Gap junction trafficking and regulation R-HSA-157858 1.204565e-05 4.919 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.279872e-05 4.893 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.295056e-05 4.888 0 0
Signaling by VEGF R-HSA-194138 1.692419e-05 4.771 0 0
Gap junction assembly R-HSA-190861 1.861689e-05 4.730 0 0
Cellular response to chemical stress R-HSA-9711123 2.026497e-05 4.693 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 2.366762e-05 4.626 0 0
Signaling by Hippo R-HSA-2028269 2.383649e-05 4.623 0 0
mRNA 3'-end processing R-HSA-72187 2.519280e-05 4.599 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.343930e-05 4.476 0 0
SARS-CoV-2 Infection R-HSA-9694516 3.401881e-05 4.468 0 0
Deubiquitination R-HSA-5688426 3.481822e-05 4.458 0 0
Chaperone Mediated Autophagy R-HSA-9613829 3.641036e-05 4.439 0 0
Ephrin signaling R-HSA-3928664 3.641036e-05 4.439 0 0
Protein folding R-HSA-391251 3.784660e-05 4.422 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 3.904239e-05 4.408 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 4.088220e-05 4.388 0 0
Folding of actin by CCT/TriC R-HSA-390450 4.102789e-05 4.387 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 4.106063e-05 4.387 0 0
HIV Life Cycle R-HSA-162587 4.264330e-05 4.370 0 0
Cellular Senescence R-HSA-2559583 4.577410e-05 4.339 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 5.001106e-05 4.301 0 0
MAP2K and MAPK activation R-HSA-5674135 5.066400e-05 4.295 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 5.161425e-05 4.287 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 6.028351e-05 4.220 0 0
Glycolysis R-HSA-70171 6.865979e-05 4.163 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 7.523871e-05 4.124 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 7.523871e-05 4.124 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 7.654513e-05 4.116 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 7.739437e-05 4.111 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 7.739437e-05 4.111 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 7.759743e-05 4.110 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 7.759743e-05 4.110 0 0
Signal transduction by L1 R-HSA-445144 7.953162e-05 4.099 0 0
Intracellular signaling by second messengers R-HSA-9006925 9.352154e-05 4.029 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 9.582625e-05 4.019 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 9.698339e-05 4.013 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.005194e-04 3.998 0 0
Signaling by ALK in cancer R-HSA-9700206 1.005194e-04 3.998 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.200369e-04 3.921 0 0
Regulation of TP53 Activity R-HSA-5633007 1.234518e-04 3.909 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.180333e-04 3.928 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.328921e-04 3.877 0 0
Nucleosome assembly R-HSA-774815 1.328921e-04 3.877 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.417085e-04 3.849 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.417085e-04 3.849 0 0
Nef and signal transduction R-HSA-164944 1.435953e-04 3.843 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.444578e-04 3.840 0 0
PTEN Regulation R-HSA-6807070 1.476421e-04 3.831 0 0
SARS-CoV Infections R-HSA-9679506 1.545771e-04 3.811 0 0
UCH proteinases R-HSA-5689603 1.569058e-04 3.804 0 0
Striated Muscle Contraction R-HSA-390522 1.660905e-04 3.780 0 0
Nucleotide Excision Repair R-HSA-5696398 1.679614e-04 3.775 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.717590e-04 3.765 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.929230e-04 3.715 0 0
Regulation of endogenous retroelements R-HSA-9842860 2.104281e-04 3.677 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 2.076110e-04 3.683 0 0
Nuclear import of Rev protein R-HSA-180746 2.153216e-04 3.667 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.987836e-04 3.702 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.971105e-04 3.705 0 0
Muscle contraction R-HSA-397014 2.179316e-04 3.662 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.355335e-04 3.628 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 2.553345e-04 3.593 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 2.579154e-04 3.589 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.766866e-04 3.558 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 2.973410e-04 3.527 0 0
EPHB-mediated forward signaling R-HSA-3928662 3.096642e-04 3.509 0 0
Nephrin family interactions R-HSA-373753 3.227096e-04 3.491 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.495483e-04 3.456 0 0
Regulation of TP53 Degradation R-HSA-6804757 3.525568e-04 3.453 0 0
MAPK family signaling cascades R-HSA-5683057 3.702988e-04 3.431 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.890086e-04 3.410 0 0
Membrane Trafficking R-HSA-199991 3.997282e-04 3.398 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 4.038834e-04 3.394 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 4.105916e-04 3.387 0 0
Neurodegenerative Diseases R-HSA-8863678 4.105916e-04 3.387 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 4.138676e-04 3.383 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 4.456369e-04 3.351 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 4.457700e-04 3.351 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 4.457700e-04 3.351 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 5.136711e-04 3.289 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 4.759414e-04 3.322 0 0
HCMV Early Events R-HSA-9609690 4.619860e-04 3.335 0 0
Diseases of programmed cell death R-HSA-9645723 5.200951e-04 3.284 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 4.648782e-04 3.333 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.592001e-04 3.338 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.589854e-04 3.338 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 5.284489e-04 3.277 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 5.457236e-04 3.263 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 5.457236e-04 3.263 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 5.589887e-04 3.253 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 5.637328e-04 3.249 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.637328e-04 3.249 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 5.754836e-04 3.240 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 6.079885e-04 3.216 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 6.198353e-04 3.208 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 6.285203e-04 3.202 0 0
Signaling by PTK6 R-HSA-8848021 6.285203e-04 3.202 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 6.574546e-04 3.182 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 6.574546e-04 3.182 0 0
Spry regulation of FGF signaling R-HSA-1295596 6.574546e-04 3.182 0 0
ESR-mediated signaling R-HSA-8939211 6.579943e-04 3.182 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 6.586047e-04 3.181 0 0
Mitophagy R-HSA-5205647 6.689329e-04 3.175 0 0
Smooth Muscle Contraction R-HSA-445355 6.830829e-04 3.166 0 0
Epigenetic regulation of gene expression R-HSA-212165 7.117707e-04 3.148 0 0
Hedgehog 'off' state R-HSA-5610787 7.506607e-04 3.125 0 0
snRNP Assembly R-HSA-191859 7.838034e-04 3.106 0 0
Metabolism of non-coding RNA R-HSA-194441 7.838034e-04 3.106 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 7.933408e-04 3.101 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 7.933408e-04 3.101 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 9.415375e-04 3.026 0 0
Regulation of signaling by CBL R-HSA-912631 8.920210e-04 3.050 0 0
mTORC1-mediated signalling R-HSA-166208 8.112709e-04 3.091 0 0
Degradation of CDH1 R-HSA-9766229 8.457639e-04 3.073 0 0
Regulation of PTEN gene transcription R-HSA-8943724 9.289206e-04 3.032 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 8.680858e-04 3.061 0 0
S Phase R-HSA-69242 8.879417e-04 3.052 0 0
COPI-mediated anterograde transport R-HSA-6807878 9.426102e-04 3.026 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 8.606789e-04 3.065 0 0
Gene Silencing by RNA R-HSA-211000 9.897628e-04 3.004 0 0
Glucose metabolism R-HSA-70326 1.013420e-03 2.994 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.027986e-03 2.988 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.027986e-03 2.988 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 1.057125e-03 2.976 0 0
FLT3 Signaling R-HSA-9607240 1.057125e-03 2.976 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.066600e-03 2.972 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.075743e-03 2.968 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.105030e-03 2.957 0 0
Gene expression (Transcription) R-HSA-74160 1.151165e-03 2.939 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 1.160773e-03 2.935 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.184225e-03 2.927 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.190534e-03 2.924 0 0
G-protein mediated events R-HSA-112040 1.202349e-03 2.920 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.242986e-03 2.906 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.242986e-03 2.906 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.258377e-03 2.900 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.264148e-03 2.898 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 1.264148e-03 2.898 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.302103e-03 2.885 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.308462e-03 2.883 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.341088e-03 2.873 0 0
HATs acetylate histones R-HSA-3214847 1.378372e-03 2.861 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 1.396378e-03 2.855 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.509930e-03 2.821 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.509930e-03 2.821 0 0
Semaphorin interactions R-HSA-373755 1.509930e-03 2.821 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.541187e-03 2.812 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.564737e-03 2.806 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.575313e-03 2.803 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.575313e-03 2.803 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.584427e-03 2.800 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.584427e-03 2.800 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.584427e-03 2.800 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.584427e-03 2.800 0 0
Infectious disease R-HSA-5663205 1.588144e-03 2.799 0 0
Basigin interactions R-HSA-210991 1.603169e-03 2.795 0 0
Regulation of PTEN stability and activity R-HSA-8948751 1.719446e-03 2.765 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.726900e-03 2.763 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 2.101213e-03 2.678 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.907141e-03 2.720 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.882998e-03 2.725 0 0
Regulation of KIT signaling R-HSA-1433559 1.907739e-03 2.719 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.205003e-03 2.657 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 2.226513e-03 2.652 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.289741e-03 2.640 0 0
Myogenesis R-HSA-525793 2.289741e-03 2.640 0 0
Metalloprotease DUBs R-HSA-5689901 2.289741e-03 2.640 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.344416e-03 2.630 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 2.344837e-03 2.630 0 0
HDACs deacetylate histones R-HSA-3214815 2.384918e-03 2.623 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.400646e-03 2.620 0 0
TCF dependent signaling in response to WNT R-HSA-201681 2.434564e-03 2.614 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.461226e-03 2.609 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 2.501933e-03 2.602 0 0
Cilium Assembly R-HSA-5617833 2.549083e-03 2.594 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 2.558897e-03 2.592 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 2.558897e-03 2.592 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.581188e-03 2.588 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 2.603061e-03 2.585 0 0
RNA Polymerase I Transcription R-HSA-73864 2.603061e-03 2.585 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 2.648040e-03 2.577 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.648040e-03 2.577 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 2.752842e-03 2.560 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.822659e-03 2.549 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.822659e-03 2.549 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 2.884765e-03 2.540 0 0
Hemostasis R-HSA-109582 2.898526e-03 2.538 0 0
tRNA processing in the nucleus R-HSA-6784531 2.992593e-03 2.524 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.199172e-03 2.495 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 3.255194e-03 2.487 0 0
G2/M DNA damage checkpoint R-HSA-69473 3.281093e-03 2.484 0 0
Orc1 removal from chromatin R-HSA-68949 3.516418e-03 2.454 0 0
Negative regulation of FLT3 R-HSA-9706369 3.595655e-03 2.444 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 3.598363e-03 2.444 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 3.775578e-03 2.423 0 0
Dual incision in TC-NER R-HSA-6782135 3.776130e-03 2.423 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 3.901855e-03 2.409 0 0
Signaling by Interleukins R-HSA-449147 4.015162e-03 2.396 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.116460e-03 2.385 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.139423e-03 2.383 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 4.139423e-03 2.383 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.253148e-03 2.371 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 4.377224e-03 2.359 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 4.382259e-03 2.358 0 0
Intraflagellar transport R-HSA-5620924 4.434222e-03 2.353 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 4.446573e-03 2.352 0 0
Late endosomal microautophagy R-HSA-9615710 4.446573e-03 2.352 0 0
DNA Double-Strand Break Repair R-HSA-5693532 4.602265e-03 2.337 0 0
HCMV Infection R-HSA-9609646 4.661243e-03 2.331 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.754979e-03 2.323 0 0
DNA Repair R-HSA-73894 4.786309e-03 2.320 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 4.786541e-03 2.320 0 0
Signaling by TGFB family members R-HSA-9006936 4.826549e-03 2.316 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 4.842522e-03 2.315 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.315950e-03 2.274 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 5.697010e-03 2.244 0 0
RAF activation R-HSA-5673000 5.291477e-03 2.276 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 5.992417e-03 2.222 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 6.081527e-03 2.216 0 0
G1/S Transition R-HSA-69206 4.920984e-03 2.308 0 0
Stabilization of p53 R-HSA-69541 5.049078e-03 2.297 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 5.049078e-03 2.297 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 5.162207e-03 2.287 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.081527e-03 2.216 0 0
Clathrin-mediated endocytosis R-HSA-8856828 5.863479e-03 2.232 0 0
Long-term potentiation R-HSA-9620244 5.463312e-03 2.263 0 0
PCP/CE pathway R-HSA-4086400 5.452526e-03 2.263 0 0
Activation of BH3-only proteins R-HSA-114452 5.446352e-03 2.264 0 0
Pexophagy R-HSA-9664873 5.697010e-03 2.244 0 0
Signaling by Hedgehog R-HSA-5358351 6.073236e-03 2.217 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 6.171139e-03 2.210 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 6.282204e-03 2.202 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 6.344694e-03 2.198 0 0
Oncogene Induced Senescence R-HSA-2559585 6.344694e-03 2.198 0 0
Ion homeostasis R-HSA-5578775 6.365287e-03 2.196 0 0
DAG and IP3 signaling R-HSA-1489509 6.554154e-03 2.183 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 6.554154e-03 2.183 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 6.615470e-03 2.179 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 6.667005e-03 2.176 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 7.071107e-03 2.151 0 0
Signaling by WNT R-HSA-195721 7.241145e-03 2.140 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 7.248084e-03 2.140 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 7.638057e-03 2.117 0 0
Centrosome maturation R-HSA-380287 7.748491e-03 2.111 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 8.050375e-03 2.094 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 8.050375e-03 2.094 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 8.161304e-03 2.088 0 0
Regulation of PTEN localization R-HSA-8948747 8.161304e-03 2.088 0 0
Negative regulation of MAPK pathway R-HSA-5675221 8.298020e-03 2.081 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 8.327108e-03 2.080 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 8.858848e-03 2.053 0 0
Co-inhibition by PD-1 R-HSA-389948 8.879749e-03 2.052 0 0
Degradation of DVL R-HSA-4641258 8.943774e-03 2.048 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 8.943774e-03 2.048 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 9.204431e-03 2.036 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 9.240859e-03 2.034 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 9.265472e-03 2.033 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 9.536094e-03 2.021 0 0
Activation of ATR in response to replication stress R-HSA-176187 9.536094e-03 2.021 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 9.536094e-03 2.021 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 9.539099e-03 2.020 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 9.554118e-03 2.020 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 9.554118e-03 2.020 0 0
DCC mediated attractive signaling R-HSA-418885 9.554118e-03 2.020 0 0
TCR signaling R-HSA-202403 9.652567e-03 2.015 0 0
MTOR signalling R-HSA-165159 9.686415e-03 2.014 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 9.772377e-03 2.010 0 0
Regulation of mitotic cell cycle R-HSA-453276 9.772377e-03 2.010 0 0
Chromosome Maintenance R-HSA-73886 9.901036e-03 2.004 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.099810e-02 1.959 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.176146e-02 1.930 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.176146e-02 1.930 0 0
MHC class II antigen presentation R-HSA-2132295 1.176955e-02 1.929 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.178479e-02 1.929 0 0
PLC beta mediated events R-HSA-112043 1.227507e-02 1.911 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.227507e-02 1.911 0 0
DNA Double Strand Break Response R-HSA-5693606 1.233684e-02 1.909 0 0
Co-inhibition by CTLA4 R-HSA-389513 1.275284e-02 1.894 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.300216e-02 1.886 0 0
DNA Replication R-HSA-69306 1.303618e-02 1.885 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.336171e-02 1.874 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 1.336171e-02 1.874 0 0
Dual Incision in GG-NER R-HSA-5696400 1.336171e-02 1.874 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 1.336171e-02 1.874 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.337971e-02 1.874 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.346544e-02 1.871 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.356293e-02 1.868 0 0
Signaling by EGFR R-HSA-177929 1.373789e-02 1.862 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.373789e-02 1.862 0 0
Signaling by NOTCH R-HSA-157118 1.383607e-02 1.859 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.385597e-02 1.858 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.431239e-02 1.844 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 1.431239e-02 1.844 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.436132e-02 1.843 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.465793e-02 1.834 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.465793e-02 1.834 0 0
p75NTR recruits signalling complexes R-HSA-209543 1.465793e-02 1.834 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.570271e-02 1.804 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.964839e-02 1.707 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.964839e-02 1.707 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 1.823495e-02 1.739 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 1.566291e-02 1.805 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 1.906183e-02 1.720 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.712909e-02 1.766 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 1.712909e-02 1.766 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.743946e-02 1.758 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.730931e-02 1.762 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.670742e-02 1.777 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.655915e-02 1.781 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.555187e-02 1.808 0 0
FLT3 signaling in disease R-HSA-9682385 1.824916e-02 1.739 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.670742e-02 1.777 0 0
Regulation of Apoptosis R-HSA-169911 1.566291e-02 1.805 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.559110e-02 1.807 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.927171e-02 1.715 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.670742e-02 1.777 0 0
Cellular response to hypoxia R-HSA-1234174 1.956119e-02 1.709 0 0
Platelet degranulation R-HSA-114608 1.770534e-02 1.752 0 0
Immune System R-HSA-168256 1.744671e-02 1.758 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.920753e-02 1.717 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.908796e-02 1.719 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.495724e-02 1.825 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.920753e-02 1.717 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.703655e-02 1.769 0 0
Maturation of protein E R-HSA-9694493 1.736159e-02 1.760 0 0
Maturation of protein E R-HSA-9683683 1.736159e-02 1.760 0 0
Meiotic synapsis R-HSA-1221632 1.973361e-02 1.705 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 1.973361e-02 1.705 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 2.113969e-02 1.675 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.113969e-02 1.675 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.139420e-02 1.670 0 0
Interaction between L1 and Ankyrins R-HSA-445095 2.167773e-02 1.664 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 2.167773e-02 1.664 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 2.183655e-02 1.661 0 0
Ca-dependent events R-HSA-111996 2.183655e-02 1.661 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.183655e-02 1.661 0 0
Co-stimulation by CD28 R-HSA-389356 2.217861e-02 1.654 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 2.224846e-02 1.653 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 2.262447e-02 1.645 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 2.262447e-02 1.645 0 0
Josephin domain DUBs R-HSA-5689877 2.262447e-02 1.645 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.262447e-02 1.645 0 0
Homology Directed Repair R-HSA-5693538 2.268576e-02 1.644 0 0
Synthesis of DNA R-HSA-69239 2.289598e-02 1.640 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 2.318515e-02 1.635 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 2.332978e-02 1.632 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 2.344284e-02 1.630 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.370355e-02 1.625 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 2.370453e-02 1.625 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 2.391855e-02 1.621 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 2.435272e-02 1.613 0 0
NRIF signals cell death from the nucleus R-HSA-205043 2.435272e-02 1.613 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 2.451465e-02 1.611 0 0
Signaling by FGFR4 R-HSA-5654743 2.489908e-02 1.604 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.499578e-02 1.602 0 0
DNA Damage Bypass R-HSA-73893 2.508358e-02 1.601 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 2.520040e-02 1.599 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 2.556351e-02 1.592 0 0
Vpu mediated degradation of CD4 R-HSA-180534 2.706367e-02 1.568 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.711597e-02 1.567 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.770860e-02 1.557 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.770860e-02 1.557 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 2.770860e-02 1.557 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 2.790798e-02 1.554 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.798705e-02 1.553 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 2.798705e-02 1.553 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.818396e-02 1.550 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 2.818396e-02 1.550 0 0
Opioid Signalling R-HSA-111885 2.818396e-02 1.550 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 2.826471e-02 1.549 0 0
Cyclin D associated events in G1 R-HSA-69231 2.826471e-02 1.549 0 0
G1 Phase R-HSA-69236 2.826471e-02 1.549 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.951532e-02 1.530 0 0
Translesion Synthesis by POLH R-HSA-110320 2.951532e-02 1.530 0 0
Rap1 signalling R-HSA-392517 2.951532e-02 1.530 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 2.975243e-02 1.526 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 2.991812e-02 1.524 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 3.050815e-02 1.516 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 3.050815e-02 1.516 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 3.050815e-02 1.516 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 3.050815e-02 1.516 0 0
p75NTR signals via NF-kB R-HSA-193639 3.050815e-02 1.516 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 3.056195e-02 1.515 0 0
RNA Polymerase II Transcription R-HSA-73857 3.068172e-02 1.513 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 3.120532e-02 1.506 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 3.120532e-02 1.506 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 3.194811e-02 1.496 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 3.194811e-02 1.496 0 0
Signaling by FGFR3 R-HSA-5654741 3.194811e-02 1.496 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 3.194811e-02 1.496 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 3.194811e-02 1.496 0 0
Organelle biogenesis and maintenance R-HSA-1852241 3.216544e-02 1.493 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 3.303719e-02 1.481 0 0
Ion transport by P-type ATPases R-HSA-936837 3.384643e-02 1.470 0 0
ER to Golgi Anterograde Transport R-HSA-199977 3.491822e-02 1.457 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.517259e-02 1.454 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.517259e-02 1.454 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 3.517259e-02 1.454 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 3.547557e-02 1.450 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 3.577407e-02 1.446 0 0
Signalling to ERKs R-HSA-187687 3.577407e-02 1.446 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 3.610876e-02 1.442 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 3.610876e-02 1.442 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.612999e-02 1.442 0 0
Prolonged ERK activation events R-HSA-169893 3.760058e-02 1.425 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 3.785292e-02 1.422 0 0
Signaling by MAP2K mutants R-HSA-9652169 3.785292e-02 1.422 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 3.815260e-02 1.418 0 0
NF-kB is activated and signals survival R-HSA-209560 3.815260e-02 1.418 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.851257e-02 1.414 0 0
Sema4D in semaphorin signaling R-HSA-400685 3.851257e-02 1.414 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 5.239722e-02 1.281 0 0
Manipulation of host energy metabolism R-HSA-9636667 5.239722e-02 1.281 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 5.508438e-02 1.259 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 5.508438e-02 1.259 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 5.508438e-02 1.259 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 5.508438e-02 1.259 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 4.694293e-02 1.328 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 4.694293e-02 1.328 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.786539e-02 1.320 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.786539e-02 1.320 0 0
CD28 dependent Vav1 pathway R-HSA-389359 5.891035e-02 1.230 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 5.891035e-02 1.230 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 4.566582e-02 1.340 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 4.227219e-02 1.374 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 4.980883e-02 1.303 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 5.182302e-02 1.285 0 0
PRC2 methylates histones and DNA R-HSA-212300 4.078769e-02 1.389 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.032302e-02 1.394 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 3.953900e-02 1.403 0 0
Signaling by ERBB4 R-HSA-1236394 4.746118e-02 1.324 0 0
Signaling by NOTCH4 R-HSA-9013694 4.746118e-02 1.324 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 5.417686e-02 1.266 0 0
Integrin signaling R-HSA-354192 5.246609e-02 1.280 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 3.966276e-02 1.402 0 0
Meiosis R-HSA-1500620 3.983621e-02 1.400 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.980883e-02 1.303 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.956304e-02 1.305 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 5.508438e-02 1.259 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.786539e-02 1.320 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 4.980883e-02 1.303 0 0
Trafficking of AMPA receptors R-HSA-399719 4.012695e-02 1.397 0 0
Budding and maturation of HIV virion R-HSA-162588 4.012695e-02 1.397 0 0
MyD88-independent TLR4 cascade R-HSA-166166 4.787675e-02 1.320 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 5.246609e-02 1.280 0 0
TNF signaling R-HSA-75893 5.367753e-02 1.270 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 4.787675e-02 1.320 0 0
Breakdown of the nuclear lamina R-HSA-352238 5.239722e-02 1.281 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 4.566582e-02 1.340 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 3.934214e-02 1.405 0 0
Signaling by SCF-KIT R-HSA-1433557 5.136330e-02 1.289 0 0
Frs2-mediated activation R-HSA-170968 5.891035e-02 1.230 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 5.246609e-02 1.280 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 4.078612e-02 1.389 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 4.078612e-02 1.389 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 4.503965e-02 1.346 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 5.136330e-02 1.289 0 0
Calmodulin induced events R-HSA-111933 4.078769e-02 1.389 0 0
Signaling by FGFR2 R-HSA-5654738 4.537364e-02 1.343 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 4.980883e-02 1.303 0 0
Vesicle-mediated transport R-HSA-5653656 5.727308e-02 1.242 0 0
CaM pathway R-HSA-111997 4.078769e-02 1.389 0 0
Death Receptor Signaling R-HSA-73887 5.345376e-02 1.272 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.484417e-02 1.348 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 5.249053e-02 1.280 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 4.694293e-02 1.328 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 5.891035e-02 1.230 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 4.078769e-02 1.389 0 0
Degradation of AXIN R-HSA-4641257 4.626210e-02 1.335 0 0
Signaling by FGFR1 R-HSA-5654736 5.367753e-02 1.270 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 5.814462e-02 1.235 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 5.356494e-02 1.271 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 5.336619e-02 1.273 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 5.246609e-02 1.280 0 0
Gluconeogenesis R-HSA-70263 4.503965e-02 1.346 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 5.367753e-02 1.270 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 5.246609e-02 1.280 0 0
Response of Mtb to phagocytosis R-HSA-9637690 5.136330e-02 1.289 0 0
Sensory processing of sound R-HSA-9659379 4.163135e-02 1.381 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.956304e-02 1.305 0 0
Modulation by Mtb of host immune system R-HSA-9637628 4.694293e-02 1.328 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.907847e-02 1.229 0 0
ER-Phagosome pathway R-HSA-1236974 5.945598e-02 1.226 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 5.947320e-02 1.226 0 0
WNT mediated activation of DVL R-HSA-201688 6.063591e-02 1.217 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 6.063591e-02 1.217 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.143415e-02 1.212 0 0
Hedgehog ligand biogenesis R-HSA-5358346 6.143415e-02 1.212 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 6.281722e-02 1.202 0 0
Developmental Cell Lineages R-HSA-9734767 6.354671e-02 1.197 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 6.364429e-02 1.196 0 0
Hedgehog 'on' state R-HSA-5632684 6.427367e-02 1.192 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.480334e-02 1.188 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 6.557885e-02 1.183 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 6.557885e-02 1.183 0 0
Generation of second messenger molecules R-HSA-202433 6.557885e-02 1.183 0 0
Antigen processing-Cross presentation R-HSA-1236975 6.656391e-02 1.177 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 6.705323e-02 1.174 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 6.705323e-02 1.174 0 0
Syndecan interactions R-HSA-3000170 6.729137e-02 1.172 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 6.767548e-02 1.170 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 6.767548e-02 1.170 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 6.767548e-02 1.170 0 0
Termination of translesion DNA synthesis R-HSA-5656169 6.777924e-02 1.169 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 6.777924e-02 1.169 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 6.777924e-02 1.169 0 0
Regulation of TNFR1 signaling R-HSA-5357905 7.044511e-02 1.152 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 7.128687e-02 1.147 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 7.128687e-02 1.147 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 7.128687e-02 1.147 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 7.301400e-02 1.137 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 7.539902e-02 1.123 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 7.539902e-02 1.123 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 7.589219e-02 1.120 0 0
The NLRP3 inflammasome R-HSA-844456 7.589219e-02 1.120 0 0
STING mediated induction of host immune responses R-HSA-1834941 7.589219e-02 1.120 0 0
Regulation of CDH11 function R-HSA-9762292 7.620757e-02 1.118 0 0
Signal attenuation R-HSA-74749 7.620757e-02 1.118 0 0
Receptor Mediated Mitophagy R-HSA-8934903 7.620757e-02 1.118 0 0
Activation of the pre-replicative complex R-HSA-68962 7.677368e-02 1.115 0 0
Deadenylation of mRNA R-HSA-429947 7.725405e-02 1.112 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 7.725405e-02 1.112 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 7.725405e-02 1.112 0 0
Degradation of CRY and PER proteins R-HSA-9932298 8.095720e-02 1.092 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 8.166733e-02 1.088 0 0
Processing of DNA double-strand break ends R-HSA-5693607 8.309761e-02 1.080 0 0
RET signaling R-HSA-8853659 8.395629e-02 1.076 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 8.497533e-02 1.071 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 8.497533e-02 1.071 0 0
Translesion synthesis by REV1 R-HSA-110312 8.497533e-02 1.071 0 0
Protein methylation R-HSA-8876725 8.497533e-02 1.071 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 8.497533e-02 1.071 0 0
Regulation of TP53 Expression R-HSA-6804754 8.615397e-02 1.065 0 0
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) R-HSA-1299308 8.615397e-02 1.065 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 8.615397e-02 1.065 0 0
EGFR downregulation R-HSA-182971 8.644934e-02 1.063 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 8.798738e-02 1.056 0 0
Negative regulation of MET activity R-HSA-6807004 8.798738e-02 1.056 0 0
Formation of definitive endoderm R-HSA-9823730 8.798738e-02 1.056 0 0
Protein ubiquitination R-HSA-8852135 8.807940e-02 1.055 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 9.085453e-02 1.042 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.328316e-02 1.030 0 0
Suppression of apoptosis R-HSA-9635465 9.357825e-02 1.029 0 0
Diseases of mitotic cell cycle R-HSA-9675126 9.680321e-02 1.014 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 9.680321e-02 1.014 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 9.694196e-02 1.013 0 0
Defective pyroptosis R-HSA-9710421 9.837423e-02 1.007 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 9.850586e-02 1.007 0 0
Signaling by LTK in cancer R-HSA-9842640 9.850586e-02 1.007 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 9.850586e-02 1.007 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 9.850586e-02 1.007 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 9.961322e-02 1.002 0 0
Translesion synthesis by POLI R-HSA-5656121 9.993874e-02 1.000 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 9.993874e-02 1.000 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 9.993874e-02 1.000 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 9.993874e-02 1.000 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.006652e-01 0.997 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.069220e-01 0.971 0 0
Regulation of necroptotic cell death R-HSA-5675482 1.078277e-01 0.967 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 1.078277e-01 0.967 0 0
Netrin-1 signaling R-HSA-373752 1.078450e-01 0.967 0 0
Drug resistance of FLT3 mutants R-HSA-9702506 1.145490e-01 0.941 0 0
FLT3 mutants bind TKIs R-HSA-9702509 1.145490e-01 0.941 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 1.145490e-01 0.941 0 0
midostaurin-resistant FLT3 mutants R-HSA-9702600 1.145490e-01 0.941 0 0
quizartinib-resistant FLT3 mutants R-HSA-9702620 1.145490e-01 0.941 0 0
tandutinib-resistant FLT3 mutants R-HSA-9702636 1.145490e-01 0.941 0 0
sorafenib-resistant FLT3 mutants R-HSA-9702624 1.145490e-01 0.941 0 0
tamatinib-resistant FLT3 mutants R-HSA-9703009 1.145490e-01 0.941 0 0
pexidartinib-resistant FLT3 mutants R-HSA-9702605 1.145490e-01 0.941 0 0
ponatinib-resistant FLT3 mutants R-HSA-9702614 1.145490e-01 0.941 0 0
crenolanib-resistant FLT3 mutants R-HSA-9702581 1.145490e-01 0.941 0 0
gilteritinib-resistant FLT3 mutants R-HSA-9702590 1.145490e-01 0.941 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 1.145490e-01 0.941 0 0
lestaurtinib-resistant FLT3 mutants R-HSA-9702596 1.145490e-01 0.941 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.145490e-01 0.941 0 0
KW2449-resistant FLT3 mutants R-HSA-9702569 1.145490e-01 0.941 0 0
semaxanib-resistant FLT3 mutants R-HSA-9702577 1.145490e-01 0.941 0 0
sunitinib-resistant FLT3 mutants R-HSA-9702632 1.145490e-01 0.941 0 0
linifanib-resistant FLT3 mutants R-HSA-9702998 1.145490e-01 0.941 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 2.159824e-01 0.666 0 0
Diseases of Telomere Maintenance R-HSA-9673013 2.159824e-01 0.666 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 2.159824e-01 0.666 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 2.159824e-01 0.666 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 2.159824e-01 0.666 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 2.159824e-01 0.666 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 2.159824e-01 0.666 0 0
Hereditary fructose intolerance R-HSA-5657560 2.159824e-01 0.666 0 0
Defective Mismatch Repair Associated With PMS2 R-HSA-5632987 2.159824e-01 0.666 0 0
TICAM1 deficiency - HSE R-HSA-5602566 2.159824e-01 0.666 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 2.159824e-01 0.666 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 2.159824e-01 0.666 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 2.159824e-01 0.666 0 0
Defective Mismatch Repair Associated With MLH1 R-HSA-5545483 2.159824e-01 0.666 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 2.159824e-01 0.666 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 2.159824e-01 0.666 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 1.246125e-01 0.904 0 0
MET interacts with TNS proteins R-HSA-8875513 1.246125e-01 0.904 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.246125e-01 0.904 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 1.662537e-01 0.779 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.662537e-01 0.779 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 1.662537e-01 0.779 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 1.662537e-01 0.779 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.240668e-01 0.906 0 0
IFNG signaling activates MAPKs R-HSA-9732724 1.240668e-01 0.906 0 0
Disinhibition of SNARE formation R-HSA-114516 1.240668e-01 0.906 0 0
Recycling of eIF2:GDP R-HSA-72731 1.240668e-01 0.906 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 2.098449e-01 0.678 0 0
Co-inhibition by BTLA R-HSA-9927353 2.098449e-01 0.678 0 0
IRS activation R-HSA-74713 2.098449e-01 0.678 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.098449e-01 0.678 0 0
NTRK2 activates RAC1 R-HSA-9032759 2.098449e-01 0.678 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 2.098449e-01 0.678 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 1.517195e-01 0.819 0 0
Type I hemidesmosome assembly R-HSA-446107 1.517195e-01 0.819 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 1.517195e-01 0.819 0 0
Formation of annular gap junctions R-HSA-196025 1.517195e-01 0.819 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.126388e-01 0.948 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 1.810949e-01 0.742 0 0
ARMS-mediated activation R-HSA-170984 1.810949e-01 0.742 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 1.810949e-01 0.742 0 0
Gap junction degradation R-HSA-190873 1.810949e-01 0.742 0 0
ALK mutants bind TKIs R-HSA-9700645 1.810949e-01 0.742 0 0
Translesion synthesis by POLK R-HSA-5655862 1.161245e-01 0.935 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 1.161245e-01 0.935 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 1.552821e-01 0.809 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.552821e-01 0.809 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.552821e-01 0.809 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.552821e-01 0.809 0 0
MAPK3 (ERK1) activation R-HSA-110056 2.118300e-01 0.674 0 0
2-LTR circle formation R-HSA-164843 2.118300e-01 0.674 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 2.118300e-01 0.674 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 2.118300e-01 0.674 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.334664e-01 0.875 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.334664e-01 0.875 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.151144e-01 0.939 0 0
GAB1 signalosome R-HSA-180292 1.518867e-01 0.818 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 1.518867e-01 0.818 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 1.119863e-01 0.951 0 0
Packaging Of Telomere Ends R-HSA-171306 1.119863e-01 0.951 0 0
p38MAPK events R-HSA-171007 2.028983e-01 0.693 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 2.028983e-01 0.693 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 2.028983e-01 0.693 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 1.712983e-01 0.766 0 0
DNA methylation R-HSA-5334118 1.390149e-01 0.857 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.318368e-01 0.880 0 0
DAP12 signaling R-HSA-2424491 1.536119e-01 0.814 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.536119e-01 0.814 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 2.127120e-01 0.672 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 2.127120e-01 0.672 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 1.247185e-01 0.904 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.363167e-01 0.865 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 1.282849e-01 0.892 0 0
G0 and Early G1 R-HSA-1538133 1.847890e-01 0.733 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 1.484514e-01 0.828 0 0
HIV Transcription Initiation R-HSA-167161 1.484514e-01 0.828 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 1.484514e-01 0.828 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 2.169959e-01 0.664 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 2.169959e-01 0.664 0 0
Cristae formation R-HSA-8949613 2.169959e-01 0.664 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 1.742535e-01 0.759 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 1.170349e-01 0.932 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.179158e-01 0.662 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.179158e-01 0.662 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 2.019479e-01 0.695 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.007508e-01 0.697 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.142768e-01 0.669 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.447850e-01 0.839 0 0
Early Phase of HIV Life Cycle R-HSA-162594 2.127120e-01 0.672 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.871092e-01 0.728 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 1.300818e-01 0.886 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.760247e-01 0.754 0 0
TGFBR3 expression R-HSA-9839394 1.800481e-01 0.745 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 1.800481e-01 0.745 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 1.583319e-01 0.800 0 0
Integration of provirus R-HSA-162592 1.126388e-01 0.948 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.178178e-01 0.929 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 2.118300e-01 0.674 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 1.662537e-01 0.779 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 2.098449e-01 0.678 0 0
Meiotic recombination R-HSA-912446 1.112103e-01 0.954 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 1.119863e-01 0.951 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 1.810949e-01 0.742 0 0
E2F mediated regulation of DNA replication R-HSA-113510 1.712983e-01 0.766 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 2.169959e-01 0.664 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 1.982012e-01 0.703 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 1.300818e-01 0.886 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.946274e-01 0.711 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 1.390149e-01 0.857 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 2.007508e-01 0.697 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.246125e-01 0.904 0 0
Pyrophosphate hydrolysis R-HSA-71737 2.098449e-01 0.678 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.126388e-01 0.948 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 1.712983e-01 0.766 0 0
Adaptive Immune System R-HSA-1280218 1.252297e-01 0.902 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 1.240668e-01 0.906 0 0
Signaling by TGFBR3 R-HSA-9839373 1.282849e-01 0.892 0 0
Generic Transcription Pathway R-HSA-212436 1.252887e-01 0.902 0 0
Regulated Necrosis R-HSA-5218859 1.423193e-01 0.847 0 0
CHL1 interactions R-HSA-447041 1.240668e-01 0.906 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 1.517195e-01 0.819 0 0
MAP kinase activation R-HSA-450294 1.419880e-01 0.848 0 0
Leishmania infection R-HSA-9658195 2.050122e-01 0.688 0 0
Parasitic Infection Pathways R-HSA-9824443 2.050122e-01 0.688 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.363167e-01 0.865 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.112103e-01 0.954 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.329320e-01 0.876 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.098449e-01 0.678 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 1.517195e-01 0.819 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 1.712983e-01 0.766 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.688835e-01 0.772 0 0
Amyloid fiber formation R-HSA-977225 2.024288e-01 0.694 0 0
Signaling by FGFR R-HSA-190236 1.236630e-01 0.908 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 1.650140e-01 0.782 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 2.159824e-01 0.666 0 0
Inhibition of PKR R-HSA-169131 2.159824e-01 0.666 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 1.246125e-01 0.904 0 0
MTF1 activates gene expression R-HSA-5660489 1.662537e-01 0.779 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 1.662537e-01 0.779 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.098449e-01 0.678 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.126388e-01 0.948 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 1.332568e-01 0.875 0 0
Unwinding of DNA R-HSA-176974 1.810949e-01 0.742 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.552821e-01 0.809 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 1.251291e-01 0.903 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.390149e-01 0.857 0 0
Protein hydroxylation R-HSA-9629569 1.916067e-01 0.718 0 0
RAS processing R-HSA-9648002 2.022763e-01 0.694 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.119863e-01 0.951 0 0
RUNX2 regulates bone development R-HSA-8941326 1.583319e-01 0.800 0 0
Innate Immune System R-HSA-168249 2.003331e-01 0.698 0 0
Inflammasomes R-HSA-622312 1.251291e-01 0.903 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 1.810949e-01 0.742 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.810949e-01 0.742 0 0
Somitogenesis R-HSA-9824272 2.019479e-01 0.695 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 1.688835e-01 0.772 0 0
Potential therapeutics for SARS R-HSA-9679191 1.811001e-01 0.742 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 1.195110e-01 0.923 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 1.240668e-01 0.906 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.517195e-01 0.819 0 0
Calnexin/calreticulin cycle R-HSA-901042 1.318368e-01 0.880 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 1.363167e-01 0.865 0 0
Interleukin-1 signaling R-HSA-9020702 2.118839e-01 0.674 0 0
ABC-family proteins mediated transport R-HSA-382556 1.385846e-01 0.858 0 0
Glycogen metabolism R-HSA-8982491 1.247185e-01 0.904 0 0
Transmission across Chemical Synapses R-HSA-112315 1.138664e-01 0.944 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 2.098449e-01 0.678 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 1.332568e-01 0.875 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 1.332568e-01 0.875 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.810949e-01 0.742 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.810949e-01 0.742 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 2.127120e-01 0.672 0 0
Apoptotic factor-mediated response R-HSA-111471 1.518867e-01 0.818 0 0
Assembly Of The HIV Virion R-HSA-175474 1.151144e-01 0.939 0 0
Signaling by KIT in disease R-HSA-9669938 1.300818e-01 0.886 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.127120e-01 0.672 0 0
G alpha (z) signalling events R-HSA-418597 1.518244e-01 0.819 0 0
Signal regulatory protein family interactions R-HSA-391160 1.785525e-01 0.748 0 0
Signaling by NOTCH3 R-HSA-9012852 1.518244e-01 0.819 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 2.127120e-01 0.672 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.421704e-01 0.847 0 0
IRAK1 recruits IKK complex R-HSA-937039 1.332568e-01 0.875 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 1.332568e-01 0.875 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.161245e-01 0.935 0 0
Inositol phosphate metabolism R-HSA-1483249 1.857809e-01 0.731 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 1.916067e-01 0.718 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.847890e-01 0.733 0 0
Interleukin-37 signaling R-HSA-9008059 1.536119e-01 0.814 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 2.022763e-01 0.694 0 0
Glycogen synthesis R-HSA-3322077 1.916067e-01 0.718 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 2.098449e-01 0.678 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 2.183211e-01 0.661 0 0
Transcription of the HIV genome R-HSA-167172 2.210378e-01 0.656 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 2.246911e-01 0.648 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.247086e-01 0.648 0 0
Signaling by NTRKs R-HSA-166520 2.247086e-01 0.648 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 2.281465e-01 0.642 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 2.281465e-01 0.642 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 2.281465e-01 0.642 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.281465e-01 0.642 0 0
Regulation of BACH1 activity R-HSA-9708530 2.281465e-01 0.642 0 0
Signaling by Nuclear Receptors R-HSA-9006931 2.300369e-01 0.638 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 2.313229e-01 0.636 0 0
Downstream TCR signaling R-HSA-202424 2.314008e-01 0.636 0 0
Base Excision Repair R-HSA-73884 2.314008e-01 0.636 0 0
Disease R-HSA-1643685 2.324988e-01 0.634 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.339903e-01 0.631 0 0
Mitochondrial calcium ion transport R-HSA-8949215 2.345107e-01 0.630 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.345107e-01 0.630 0 0
Signal amplification R-HSA-392518 2.358505e-01 0.627 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 2.358505e-01 0.627 0 0
HIV elongation arrest and recovery R-HSA-167287 2.363630e-01 0.626 0 0
Pausing and recovery of HIV elongation R-HSA-167290 2.363630e-01 0.626 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.380267e-01 0.623 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.426153e-01 0.615 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 2.448092e-01 0.611 0 0
Interleukin-17 signaling R-HSA-448424 2.464511e-01 0.608 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.465667e-01 0.608 0 0
Telomere Maintenance R-HSA-157579 2.482235e-01 0.605 0 0
Reproduction R-HSA-1474165 2.497175e-01 0.603 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 2.541242e-01 0.595 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 2.541242e-01 0.595 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.543935e-01 0.594 0 0
Pentose phosphate pathway disease R-HSA-6791465 2.543935e-01 0.594 0 0
Phosphorylation of Emi1 R-HSA-176417 2.543935e-01 0.594 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.543935e-01 0.594 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.543935e-01 0.594 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 2.543935e-01 0.594 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 2.543935e-01 0.594 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 2.562309e-01 0.591 0 0
Platelet calcium homeostasis R-HSA-418360 2.562309e-01 0.591 0 0
NRAGE signals death through JNK R-HSA-193648 2.568974e-01 0.590 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 2.568976e-01 0.590 0 0
FGFR2 alternative splicing R-HSA-6803529 2.568976e-01 0.590 0 0
Post-translational protein phosphorylation R-HSA-8957275 2.593257e-01 0.586 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.593257e-01 0.586 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.593257e-01 0.586 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.593257e-01 0.586 0 0
Interleukin-1 family signaling R-HSA-446652 2.593622e-01 0.586 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 2.621394e-01 0.581 0 0
GPVI-mediated activation cascade R-HSA-114604 2.721778e-01 0.565 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 2.760109e-01 0.559 0 0
Activation of RAC1 R-HSA-428540 2.760109e-01 0.559 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 2.760109e-01 0.559 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.774511e-01 0.557 0 0
Signaling by MET R-HSA-6806834 2.791815e-01 0.554 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.791815e-01 0.554 0 0
Growth hormone receptor signaling R-HSA-982772 2.797669e-01 0.553 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 2.806622e-01 0.552 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 2.806622e-01 0.552 0 0
Glycogen storage diseases R-HSA-3229121 2.806622e-01 0.552 0 0
Parasite infection R-HSA-9664407 2.816161e-01 0.550 0 0
Leishmania phagocytosis R-HSA-9664417 2.816161e-01 0.550 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 2.816161e-01 0.550 0 0
TBC/RABGAPs R-HSA-8854214 2.844245e-01 0.546 0 0
Cleavage of the damaged purine R-HSA-110331 2.908685e-01 0.536 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.913338e-01 0.536 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.971783e-01 0.527 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 2.974173e-01 0.527 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 2.991086e-01 0.524 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.991086e-01 0.524 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 2.991086e-01 0.524 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.991086e-01 0.524 0 0
G2/M DNA replication checkpoint R-HSA-69478 2.991086e-01 0.524 0 0
Autointegration results in viral DNA circles R-HSA-177539 2.991086e-01 0.524 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 2.991086e-01 0.524 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 2.991086e-01 0.524 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.991086e-01 0.524 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 2.991086e-01 0.524 0 0
Proteasome assembly R-HSA-9907900 3.018350e-01 0.520 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 3.020353e-01 0.520 0 0
HCMV Late Events R-HSA-9610379 3.054116e-01 0.515 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 3.058013e-01 0.515 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 3.058013e-01 0.515 0 0
TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P R-HSA-6791462 3.058013e-01 0.515 0 0
TRAF3 deficiency - HSE R-HSA-5602571 3.058013e-01 0.515 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 3.058013e-01 0.515 0 0
TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P R-HSA-6791055 3.058013e-01 0.515 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 3.058013e-01 0.515 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 3.058013e-01 0.515 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 3.058013e-01 0.515 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 3.058013e-01 0.515 0 0
Oligomerization of connexins into connexons R-HSA-190704 3.058013e-01 0.515 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 3.058013e-01 0.515 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 3.058013e-01 0.515 0 0
Transport of connexins along the secretory pathway R-HSA-190827 3.058013e-01 0.515 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 3.058013e-01 0.515 0 0
NTRK3 as a dependence receptor R-HSA-9603505 3.058013e-01 0.515 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 3.075966e-01 0.512 0 0
Polo-like kinase mediated events R-HSA-156711 3.075966e-01 0.512 0 0
Mismatch Repair R-HSA-5358508 3.075966e-01 0.512 0 0
Platelet sensitization by LDL R-HSA-432142 3.075966e-01 0.512 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 3.075966e-01 0.512 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 3.075966e-01 0.512 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 3.075966e-01 0.512 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 3.088233e-01 0.510 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 3.088308e-01 0.510 0 0
Repression of WNT target genes R-HSA-4641265 3.088308e-01 0.510 0 0
Leading Strand Synthesis R-HSA-69109 3.088308e-01 0.510 0 0
Polymerase switching R-HSA-69091 3.088308e-01 0.510 0 0
Scavenging by Class F Receptors R-HSA-3000484 3.088308e-01 0.510 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 3.088308e-01 0.510 0 0
Depurination R-HSA-73927 3.098383e-01 0.509 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 3.145502e-01 0.502 0 0
DNA strand elongation R-HSA-69190 3.181120e-01 0.497 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 3.181120e-01 0.497 0 0
Fanconi Anemia Pathway R-HSA-6783310 3.194745e-01 0.496 0 0
Tight junction interactions R-HSA-420029 3.265369e-01 0.486 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 3.265369e-01 0.486 0 0
HDMs demethylate histones R-HSA-3214842 3.265369e-01 0.486 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.290329e-01 0.483 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 3.290329e-01 0.483 0 0
Regulation of pyruvate metabolism R-HSA-9861718 3.373006e-01 0.472 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 3.392567e-01 0.469 0 0
G-protein beta:gamma signalling R-HSA-397795 3.392567e-01 0.469 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.392567e-01 0.469 0 0
Neuronal System R-HSA-112316 3.395284e-01 0.469 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 3.417654e-01 0.466 0 0
Formation of axial mesoderm R-HSA-9796292 3.417654e-01 0.466 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 3.417654e-01 0.466 0 0
MECP2 regulates transcription factors R-HSA-9022707 3.433679e-01 0.464 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 3.433679e-01 0.464 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.433679e-01 0.464 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.433679e-01 0.464 0 0
SOS-mediated signalling R-HSA-112412 3.433679e-01 0.464 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.433679e-01 0.464 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 3.433679e-01 0.464 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.433679e-01 0.464 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 3.433679e-01 0.464 0 0
HIV Transcription Elongation R-HSA-167169 3.483986e-01 0.458 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.483986e-01 0.458 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.483986e-01 0.458 0 0
Suppression of phagosomal maturation R-HSA-9637687 3.502362e-01 0.456 0 0
Unfolded Protein Response (UPR) R-HSA-381119 3.504972e-01 0.455 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 3.555618e-01 0.449 0 0
ABC transporter disorders R-HSA-5619084 3.566576e-01 0.448 0 0
Effects of PIP2 hydrolysis R-HSA-114508 3.605422e-01 0.443 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 3.620405e-01 0.441 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 3.620405e-01 0.441 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 3.662579e-01 0.436 0 0
GPER1 signaling R-HSA-9634597 3.733445e-01 0.428 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.740170e-01 0.427 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.740170e-01 0.427 0 0
Maturation of hRSV A proteins R-HSA-9828806 3.740170e-01 0.427 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 3.741003e-01 0.427 0 0
CRMPs in Sema3A signaling R-HSA-399956 3.745726e-01 0.426 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 3.745726e-01 0.426 0 0
Signaling by FGFR4 in disease R-HSA-5655291 3.745726e-01 0.426 0 0
Malate-aspartate shuttle R-HSA-9856872 3.745726e-01 0.426 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.812184e-01 0.419 0 0
NOD1/2 Signaling Pathway R-HSA-168638 3.819008e-01 0.418 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 3.853350e-01 0.414 0 0
Signaling by RAS GAP mutants R-HSA-9753510 3.853350e-01 0.414 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 3.853350e-01 0.414 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.853350e-01 0.414 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 3.853350e-01 0.414 0 0
mRNA Editing: A to I Conversion R-HSA-75064 3.853350e-01 0.414 0 0
C6 deamination of adenosine R-HSA-75102 3.853350e-01 0.414 0 0
Signalling to ERK5 R-HSA-198765 3.853350e-01 0.414 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 3.853350e-01 0.414 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 3.853350e-01 0.414 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 3.853350e-01 0.414 0 0
phospho-PLA2 pathway R-HSA-111995 3.866892e-01 0.413 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.866892e-01 0.413 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 3.866892e-01 0.413 0 0
Adrenoceptors R-HSA-390696 3.866892e-01 0.413 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 3.866892e-01 0.413 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 3.866892e-01 0.413 0 0
RSK activation R-HSA-444257 3.866892e-01 0.413 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.874337e-01 0.412 0 0
Translation of Structural Proteins R-HSA-9683701 3.874337e-01 0.412 0 0
ERK/MAPK targets R-HSA-198753 3.892668e-01 0.410 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 3.892668e-01 0.410 0 0
Signalling to RAS R-HSA-167044 3.892668e-01 0.410 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 3.914610e-01 0.407 0 0
Ion channel transport R-HSA-983712 3.936427e-01 0.405 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.977892e-01 0.400 0 0
Pyroptosis R-HSA-5620971 3.977892e-01 0.400 0 0
Ca2+ pathway R-HSA-4086398 3.986547e-01 0.399 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 4.020115e-01 0.396 0 0
Interferon alpha/beta signaling R-HSA-909733 4.035259e-01 0.394 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 4.070016e-01 0.390 0 0
Depyrimidination R-HSA-73928 4.070016e-01 0.390 0 0
Erythropoietin activates RAS R-HSA-9027284 4.070393e-01 0.390 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 4.070393e-01 0.390 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 4.163251e-01 0.381 0 0
Signaling by Erythropoietin R-HSA-9006335 4.214680e-01 0.375 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 4.214680e-01 0.375 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.221338e-01 0.375 0 0
G1/S-Specific Transcription R-HSA-69205 4.245797e-01 0.372 0 0
Cardiac conduction R-HSA-5576891 4.267724e-01 0.370 0 0
Lipophagy R-HSA-9613354 4.287068e-01 0.368 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 4.287068e-01 0.368 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 4.287068e-01 0.368 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 4.287068e-01 0.368 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 4.287068e-01 0.368 0 0
Calcineurin activates NFAT R-HSA-2025928 4.287068e-01 0.368 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 4.287068e-01 0.368 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 4.287068e-01 0.368 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 4.287068e-01 0.368 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 4.287068e-01 0.368 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 4.291778e-01 0.367 0 0
Circadian clock R-HSA-9909396 4.382098e-01 0.358 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 4.389814e-01 0.358 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 4.389814e-01 0.358 0 0
Phosphorylation of the APC/C R-HSA-176412 4.389814e-01 0.358 0 0
Killing mechanisms R-HSA-9664420 4.389814e-01 0.358 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 4.389814e-01 0.358 0 0
Activation of SMO R-HSA-5635838 4.389814e-01 0.358 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 4.414647e-01 0.355 0 0
Activation of HOX genes during differentiation R-HSA-5619507 4.414647e-01 0.355 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 4.431017e-01 0.353 0 0
DAP12 interactions R-HSA-2172127 4.459983e-01 0.351 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 4.519672e-01 0.345 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 4.519672e-01 0.345 0 0
PLC-gamma1 signalling R-HSA-167021 4.557607e-01 0.341 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 4.557607e-01 0.341 0 0
Axonal growth stimulation R-HSA-209563 4.557607e-01 0.341 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 4.557607e-01 0.341 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 4.557607e-01 0.341 0 0
MET activates PTPN11 R-HSA-8865999 4.557607e-01 0.341 0 0
STAT6-mediated induction of chemokines R-HSA-3249367 4.557607e-01 0.341 0 0
Intracellular oxygen transport R-HSA-8981607 4.557607e-01 0.341 0 0
The NLRP1 inflammasome R-HSA-844455 4.557607e-01 0.341 0 0
Formation of paraxial mesoderm R-HSA-9793380 4.624143e-01 0.335 0 0
MET promotes cell motility R-HSA-8875878 4.668103e-01 0.331 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 4.668103e-01 0.331 0 0
FOXO-mediated transcription R-HSA-9614085 4.690158e-01 0.329 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 4.691508e-01 0.329 0 0
Binding and entry of HIV virion R-HSA-173107 4.691508e-01 0.329 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 4.691508e-01 0.329 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 4.691508e-01 0.329 0 0
Tandem pore domain potassium channels R-HSA-1296346 4.691508e-01 0.329 0 0
Regulation of the apoptosome activity R-HSA-9627069 4.691508e-01 0.329 0 0
Formation of apoptosome R-HSA-111458 4.691508e-01 0.329 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 4.694942e-01 0.328 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 4.694942e-01 0.328 0 0
Disorders of Developmental Biology R-HSA-9675151 4.702419e-01 0.328 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 4.702419e-01 0.328 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 4.702419e-01 0.328 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 4.702419e-01 0.328 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 4.702419e-01 0.328 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 4.702419e-01 0.328 0 0
Synthesis of PG R-HSA-1483148 4.702419e-01 0.328 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 4.780962e-01 0.320 0 0
NCAM signaling for neurite out-growth R-HSA-375165 4.792215e-01 0.319 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 4.845149e-01 0.315 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 4.845149e-01 0.315 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 4.845149e-01 0.315 0 0
Diseases of DNA repair R-HSA-9675135 4.845149e-01 0.315 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 4.871365e-01 0.312 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 4.876218e-01 0.312 0 0
Pentose phosphate pathway R-HSA-71336 4.876218e-01 0.312 0 0
Plasma lipoprotein clearance R-HSA-8964043 4.876218e-01 0.312 0 0
Signaling by ALK R-HSA-201556 4.876218e-01 0.312 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 4.881734e-01 0.311 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 4.881734e-01 0.311 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 4.954120e-01 0.305 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.954120e-01 0.305 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.984195e-01 0.302 0 0
Metabolism of proteins R-HSA-392499 5.000918e-01 0.301 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 5.006897e-01 0.300 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 5.006897e-01 0.300 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 5.065178e-01 0.295 0 0
Formation of the posterior neural plate R-HSA-9832991 5.078303e-01 0.294 0 0
Bicarbonate transporters R-HSA-425381 5.078303e-01 0.294 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 5.078303e-01 0.294 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 5.078303e-01 0.294 0 0
Interleukin-2 signaling R-HSA-9020558 5.078303e-01 0.294 0 0
ChREBP activates metabolic gene expression R-HSA-163765 5.078303e-01 0.294 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 5.078303e-01 0.294 0 0
Protein localization R-HSA-9609507 5.122338e-01 0.291 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 5.181209e-01 0.286 0 0
HCN channels R-HSA-1296061 5.181209e-01 0.286 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 5.181209e-01 0.286 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 5.181209e-01 0.286 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 5.181209e-01 0.286 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 5.181209e-01 0.286 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 5.181209e-01 0.286 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 5.181209e-01 0.286 0 0
Regulation of gap junction activity R-HSA-191650 5.181209e-01 0.286 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 5.181209e-01 0.286 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 5.181209e-01 0.286 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 5.181209e-01 0.286 0 0
Dopamine receptors R-HSA-390651 5.181209e-01 0.286 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 5.181209e-01 0.286 0 0
NADE modulates death signalling R-HSA-205025 5.181209e-01 0.286 0 0
TNFR1-mediated ceramide production R-HSA-5626978 5.181209e-01 0.286 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 5.181209e-01 0.286 0 0
Toxicity of tetanus toxin (tetX) R-HSA-5250982 5.181209e-01 0.286 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 5.207757e-01 0.283 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 5.302174e-01 0.276 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 5.357355e-01 0.271 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 5.357355e-01 0.271 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 5.357355e-01 0.271 0 0
Signaling by FGFR in disease R-HSA-1226099 5.393334e-01 0.268 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 5.446189e-01 0.264 0 0
ERKs are inactivated R-HSA-202670 5.446189e-01 0.264 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 5.446189e-01 0.264 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 5.446189e-01 0.264 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 5.446189e-01 0.264 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 5.446189e-01 0.264 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 5.446189e-01 0.264 0 0
Iron uptake and transport R-HSA-917937 5.545354e-01 0.256 0 0
eNOS activation R-HSA-203615 5.575899e-01 0.254 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 5.575899e-01 0.254 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 5.575899e-01 0.254 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 5.575899e-01 0.254 0 0
Signaling by NOTCH2 R-HSA-1980145 5.575899e-01 0.254 0 0
Gastrulation R-HSA-9758941 5.581956e-01 0.253 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 5.587396e-01 0.253 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 5.587396e-01 0.253 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 5.587396e-01 0.253 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 5.587396e-01 0.253 0 0
Azathioprine ADME R-HSA-9748787 5.588739e-01 0.253 0 0
Peroxisomal protein import R-HSA-9033241 5.682172e-01 0.245 0 0
Signaling by NOTCH1 R-HSA-1980143 5.695377e-01 0.244 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 5.695783e-01 0.244 0 0
Toll-like Receptor Cascades R-HSA-168898 5.703662e-01 0.244 0 0
IRE1alpha activates chaperones R-HSA-381070 5.712644e-01 0.243 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 5.733390e-01 0.242 0 0
G2 Phase R-HSA-68911 5.733390e-01 0.242 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 5.733390e-01 0.242 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 5.733390e-01 0.242 0 0
Defective F9 activation R-HSA-9673221 5.733390e-01 0.242 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 5.733390e-01 0.242 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 5.733390e-01 0.242 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 5.733390e-01 0.242 0 0
Activation of AKT2 R-HSA-165158 5.733390e-01 0.242 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 5.733390e-01 0.242 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 5.733390e-01 0.242 0 0
Suppression of autophagy R-HSA-9636569 5.733390e-01 0.242 0 0
Muscarinic acetylcholine receptors R-HSA-390648 5.733390e-01 0.242 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 5.733390e-01 0.242 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 5.733390e-01 0.242 0 0
Reelin signalling pathway R-HSA-8866376 5.733390e-01 0.242 0 0
NrCAM interactions R-HSA-447038 5.733390e-01 0.242 0 0
The phototransduction cascade R-HSA-2514856 5.767169e-01 0.239 0 0
PERK regulates gene expression R-HSA-381042 5.787511e-01 0.238 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 5.787511e-01 0.238 0 0
Pervasive developmental disorders R-HSA-9005895 5.794419e-01 0.237 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 5.794419e-01 0.237 0 0
Disorders of Nervous System Development R-HSA-9697154 5.794419e-01 0.237 0 0
GRB2 events in EGFR signaling R-HSA-179812 5.794419e-01 0.237 0 0
Regulation of IFNG signaling R-HSA-877312 5.794419e-01 0.237 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 5.794419e-01 0.237 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 5.861906e-01 0.232 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 5.861906e-01 0.232 0 0
Signaling by NODAL R-HSA-1181150 5.861906e-01 0.232 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 5.929115e-01 0.227 0 0
Formation of the Early Elongation Complex R-HSA-113418 5.929115e-01 0.227 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 5.942072e-01 0.226 0 0
Integrin cell surface interactions R-HSA-216083 5.988780e-01 0.223 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 5.993608e-01 0.222 0 0
RNA Polymerase III Transcription R-HSA-74158 5.993608e-01 0.222 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 6.037005e-01 0.219 0 0
XBP1(S) activates chaperone genes R-HSA-381038 6.052185e-01 0.218 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 6.122669e-01 0.213 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 6.122669e-01 0.213 0 0
Maturation of nucleoprotein R-HSA-9683610 6.122669e-01 0.213 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 6.122669e-01 0.213 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 6.125224e-01 0.213 0 0
Lagging Strand Synthesis R-HSA-69186 6.125224e-01 0.213 0 0
mRNA Capping R-HSA-72086 6.154781e-01 0.211 0 0
Mitochondrial protein import R-HSA-1268020 6.168717e-01 0.210 0 0
Pyruvate metabolism R-HSA-70268 6.187770e-01 0.208 0 0
Plus-strand DNA synthesis R-HSA-164525 6.222326e-01 0.206 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 6.222326e-01 0.206 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 6.222326e-01 0.206 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 6.222326e-01 0.206 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 6.222326e-01 0.206 0 0
Signaling by MAPK mutants R-HSA-9652817 6.222326e-01 0.206 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 6.222326e-01 0.206 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 6.222326e-01 0.206 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 6.222326e-01 0.206 0 0
PKB-mediated events R-HSA-109703 6.222326e-01 0.206 0 0
PDE3B signalling R-HSA-165160 6.222326e-01 0.206 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 6.222326e-01 0.206 0 0
Synthesis of PS R-HSA-1483101 6.222326e-01 0.206 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 6.222326e-01 0.206 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 6.222326e-01 0.206 0 0
Intestinal hexose absorption R-HSA-8981373 6.222326e-01 0.206 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 6.222326e-01 0.206 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 6.222326e-01 0.206 0 0
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397 6.222326e-01 0.206 0 0
Acetylcholine inhibits contraction of outer hair cells R-HSA-9667769 6.222326e-01 0.206 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 6.222326e-01 0.206 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 6.222326e-01 0.206 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 6.222326e-01 0.206 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 6.236591e-01 0.205 0 0
Rab regulation of trafficking R-HSA-9007101 6.273056e-01 0.203 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 6.280439e-01 0.202 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 6.367633e-01 0.196 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 6.367633e-01 0.196 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 6.372481e-01 0.196 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 6.372481e-01 0.196 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 6.377028e-01 0.195 0 0
Ribavirin ADME R-HSA-9755088 6.377028e-01 0.195 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 6.388101e-01 0.195 0 0
Removal of the Flap Intermediate R-HSA-69166 6.430943e-01 0.192 0 0
cGMP effects R-HSA-418457 6.430943e-01 0.192 0 0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA R-HSA-77310 6.430943e-01 0.192 0 0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA R-HSA-77350 6.430943e-01 0.192 0 0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA R-HSA-77348 6.430943e-01 0.192 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 6.430943e-01 0.192 0 0
Acyl chain remodeling of CL R-HSA-1482798 6.430943e-01 0.192 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 6.430943e-01 0.192 0 0
Insulin receptor signalling cascade R-HSA-74751 6.476333e-01 0.189 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 6.576051e-01 0.182 0 0
Molecules associated with elastic fibres R-HSA-2129379 6.581995e-01 0.182 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.617134e-01 0.179 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 6.617134e-01 0.179 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 6.617134e-01 0.179 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 6.617134e-01 0.179 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 6.655257e-01 0.177 0 0
STAT5 Activation R-HSA-9645135 6.655257e-01 0.177 0 0
Uncoating of the HIV Virion R-HSA-162585 6.655257e-01 0.177 0 0
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) R-HSA-5619070 6.655257e-01 0.177 0 0
Neurofascin interactions R-HSA-447043 6.655257e-01 0.177 0 0
CREB phosphorylation R-HSA-199920 6.655257e-01 0.177 0 0
VLDL assembly R-HSA-8866423 6.655257e-01 0.177 0 0
SHC1 events in EGFR signaling R-HSA-180336 6.719510e-01 0.173 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 6.719510e-01 0.173 0 0
Processive synthesis on the lagging strand R-HSA-69183 6.719510e-01 0.173 0 0
Formation of the anterior neural plate R-HSA-9823739 6.719510e-01 0.173 0 0
Signaling by Activin R-HSA-1502540 6.719510e-01 0.173 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 6.845479e-01 0.165 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 6.845479e-01 0.165 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.845479e-01 0.165 0 0
tRNA processing R-HSA-72306 6.906503e-01 0.161 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 6.906829e-01 0.161 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 6.912681e-01 0.160 0 0
Disorders of transmembrane transporters R-HSA-5619115 6.938253e-01 0.159 0 0
Nuclear RNA decay R-HSA-9930044 6.975942e-01 0.156 0 0
FGFR1 mutant receptor activation R-HSA-1839124 6.975942e-01 0.156 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 6.988836e-01 0.156 0 0
Phase 4 - resting membrane potential R-HSA-5576886 6.988836e-01 0.156 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 6.988836e-01 0.156 0 0
Virus Assembly and Release R-HSA-168268 6.988836e-01 0.156 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 7.038595e-01 0.153 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 7.038595e-01 0.153 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 7.038595e-01 0.153 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 7.038595e-01 0.153 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 7.038595e-01 0.153 0 0
VLDL clearance R-HSA-8964046 7.038595e-01 0.153 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 7.038595e-01 0.153 0 0
LDL remodeling R-HSA-8964041 7.038595e-01 0.153 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 7.038595e-01 0.153 0 0
Netrin mediated repulsion signals R-HSA-418886 7.038595e-01 0.153 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 7.038595e-01 0.153 0 0
Translation of Structural Proteins R-HSA-9694635 7.048499e-01 0.152 0 0
Regulation of beta-cell development R-HSA-186712 7.052268e-01 0.152 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.055380e-01 0.151 0 0
Complex III assembly R-HSA-9865881 7.062102e-01 0.151 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 7.062102e-01 0.151 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.062102e-01 0.151 0 0
Signaling by FGFR2 in disease R-HSA-5655253 7.068468e-01 0.151 0 0
G alpha (12/13) signalling events R-HSA-416482 7.174345e-01 0.144 0 0
RAB geranylgeranylation R-HSA-8873719 7.193103e-01 0.143 0 0
tRNA Aminoacylation R-HSA-379724 7.193103e-01 0.143 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 7.239541e-01 0.140 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 7.239541e-01 0.140 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 7.239541e-01 0.140 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 7.239541e-01 0.140 0 0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA R-HSA-77346 7.239541e-01 0.140 0 0
Galactose catabolism R-HSA-70370 7.239541e-01 0.140 0 0
Coenzyme A biosynthesis R-HSA-196783 7.239541e-01 0.140 0 0
Passive transport by Aquaporins R-HSA-432047 7.239541e-01 0.140 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 7.239541e-01 0.140 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 7.239541e-01 0.140 0 0
Response to metal ions R-HSA-5660526 7.239541e-01 0.140 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 7.262844e-01 0.139 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 7.262844e-01 0.139 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.267131e-01 0.139 0 0
Laminin interactions R-HSA-3000157 7.267131e-01 0.139 0 0
Formation of the nephric duct R-HSA-9830364 7.267131e-01 0.139 0 0
Interleukin-7 signaling R-HSA-1266695 7.267131e-01 0.139 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.267131e-01 0.139 0 0
Neurexins and neuroligins R-HSA-6794361 7.363715e-01 0.133 0 0
Reverse Transcription of HIV RNA R-HSA-162589 7.378019e-01 0.132 0 0
Minus-strand DNA synthesis R-HSA-164516 7.378019e-01 0.132 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 7.378019e-01 0.132 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 7.378019e-01 0.132 0 0
MET receptor recycling R-HSA-8875656 7.378019e-01 0.132 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 7.378019e-01 0.132 0 0
Regulation by c-FLIP R-HSA-3371378 7.378019e-01 0.132 0 0
Fructose biosynthesis R-HSA-5652227 7.378019e-01 0.132 0 0
Activation of RAS in B cells R-HSA-1169092 7.378019e-01 0.132 0 0
FGFR1b ligand binding and activation R-HSA-190370 7.378019e-01 0.132 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 7.378019e-01 0.132 0 0
Dimerization of procaspase-8 R-HSA-69416 7.378019e-01 0.132 0 0
TGFBR3 PTM regulation R-HSA-9839383 7.378019e-01 0.132 0 0
Intestinal absorption R-HSA-8963676 7.378019e-01 0.132 0 0
Interleukin-23 signaling R-HSA-9020933 7.378019e-01 0.132 0 0
MET activates PTK2 signaling R-HSA-8874081 7.460769e-01 0.127 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 7.460769e-01 0.127 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.460769e-01 0.127 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 7.460769e-01 0.127 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 7.472356e-01 0.127 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 7.472356e-01 0.127 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 7.472356e-01 0.127 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 7.472356e-01 0.127 0 0
Specification of primordial germ cells R-HSA-9827857 7.472356e-01 0.127 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 7.472356e-01 0.127 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 7.533314e-01 0.123 0 0
Amine ligand-binding receptors R-HSA-375280 7.566674e-01 0.121 0 0
Integration of energy metabolism R-HSA-163685 7.602297e-01 0.119 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.643277e-01 0.117 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.643277e-01 0.117 0 0
Triglyceride catabolism R-HSA-163560 7.663139e-01 0.116 0 0
MAPK1 (ERK2) activation R-HSA-112411 7.678558e-01 0.115 0 0
CASP8 activity is inhibited R-HSA-5218900 7.678558e-01 0.115 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 7.678558e-01 0.115 0 0
p75NTR regulates axonogenesis R-HSA-193697 7.678558e-01 0.115 0 0
mRNA Editing R-HSA-75072 7.678558e-01 0.115 0 0
Regulation of signaling by NODAL R-HSA-1433617 7.678558e-01 0.115 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 7.678558e-01 0.115 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 7.678558e-01 0.115 0 0
Regulated proteolysis of p75NTR R-HSA-193692 7.678558e-01 0.115 0 0
Interleukin-1 processing R-HSA-448706 7.678558e-01 0.115 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 7.678558e-01 0.115 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 7.678558e-01 0.115 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 7.678558e-01 0.115 0 0
PKA activation R-HSA-163615 7.688086e-01 0.114 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 7.688086e-01 0.114 0 0
PKA activation in glucagon signalling R-HSA-164378 7.688086e-01 0.114 0 0
Nephron development R-HSA-9831926 7.688086e-01 0.114 0 0
Platelet homeostasis R-HSA-418346 7.697416e-01 0.114 0 0
Regulation of insulin secretion R-HSA-422356 7.708932e-01 0.113 0 0
Insulin receptor recycling R-HSA-77387 7.814970e-01 0.107 0 0
Post-translational protein modification R-HSA-597592 7.883421e-01 0.103 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 7.887588e-01 0.103 0 0
Germ layer formation at gastrulation R-HSA-9754189 7.887588e-01 0.103 0 0
Specification of the neural plate border R-HSA-9834899 7.887588e-01 0.103 0 0
Maturation of nucleoprotein R-HSA-9694631 7.887588e-01 0.103 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 7.887588e-01 0.103 0 0
Signaling by Insulin receptor R-HSA-74752 7.923467e-01 0.101 0 0
PI3K/AKT activation R-HSA-198203 7.944663e-01 0.100 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 7.944663e-01 0.100 0 0
DNA replication initiation R-HSA-68952 7.944663e-01 0.100 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 7.944663e-01 0.100 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 7.944663e-01 0.100 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.944663e-01 0.100 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 7.944663e-01 0.100 0 0
Sperm Motility And Taxes R-HSA-1300642 7.944663e-01 0.100 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 7.944663e-01 0.100 0 0
Serotonin receptors R-HSA-390666 7.944663e-01 0.100 0 0
Interleukin-27 signaling R-HSA-9020956 7.944663e-01 0.100 0 0
Maturation of spike protein R-HSA-9683686 7.944663e-01 0.100 0 0
Signaling by Leptin R-HSA-2586552 7.944663e-01 0.100 0 0
Elastic fibre formation R-HSA-1566948 7.957849e-01 0.099 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.976198e-01 0.098 0 0
DARPP-32 events R-HSA-180024 7.976198e-01 0.098 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.017439e-01 0.096 0 0
Mitochondrial biogenesis R-HSA-1592230 8.037404e-01 0.095 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 8.071749e-01 0.093 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 8.071749e-01 0.093 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 8.071749e-01 0.093 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 8.071749e-01 0.093 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 8.071749e-01 0.093 0 0
Pregnenolone biosynthesis R-HSA-196108 8.071749e-01 0.093 0 0
Mitochondrial protein degradation R-HSA-9837999 8.108231e-01 0.091 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.127344e-01 0.090 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 8.127344e-01 0.090 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 8.127344e-01 0.090 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 8.127344e-01 0.090 0 0
Neddylation R-HSA-8951664 8.136783e-01 0.090 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 8.180279e-01 0.087 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 8.180279e-01 0.087 0 0
vRNP Assembly R-HSA-192905 8.180279e-01 0.087 0 0
vRNA Synthesis R-HSA-192814 8.180279e-01 0.087 0 0
Conjugation of benzoate with glycine R-HSA-177135 8.180279e-01 0.087 0 0
Chylomicron assembly R-HSA-8963888 8.180279e-01 0.087 0 0
Synthesis of PI R-HSA-1483226 8.180279e-01 0.087 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 8.180279e-01 0.087 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 8.180279e-01 0.087 0 0
Dissolution of Fibrin Clot R-HSA-75205 8.180279e-01 0.087 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.221844e-01 0.085 0 0
Diseases of Immune System R-HSA-5260271 8.221844e-01 0.085 0 0
Extension of Telomeres R-HSA-180786 8.227620e-01 0.085 0 0
Amino acid transport across the plasma membrane R-HSA-352230 8.227620e-01 0.085 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 8.241462e-01 0.084 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 8.241462e-01 0.084 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 8.241462e-01 0.084 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 8.241462e-01 0.084 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 8.241462e-01 0.084 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 8.241462e-01 0.084 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 8.241462e-01 0.084 0 0
Downstream signal transduction R-HSA-186763 8.268813e-01 0.083 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 8.330413e-01 0.079 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 8.330413e-01 0.079 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 8.330413e-01 0.079 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 8.330413e-01 0.079 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 8.330413e-01 0.079 0 0
Metabolism of polyamines R-HSA-351202 8.330413e-01 0.079 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 8.342894e-01 0.079 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 8.388896e-01 0.076 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 8.388896e-01 0.076 0 0
Signaling by GSK3beta mutants R-HSA-5339716 8.388896e-01 0.076 0 0
Plasmalogen biosynthesis R-HSA-75896 8.388896e-01 0.076 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 8.388896e-01 0.076 0 0
Sodium/Calcium exchangers R-HSA-425561 8.388896e-01 0.076 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 8.388896e-01 0.076 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 8.397619e-01 0.076 0 0
Serine metabolism R-HSA-977347 8.397619e-01 0.076 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 8.397619e-01 0.076 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 8.401024e-01 0.076 0 0
Leishmania parasite growth and survival R-HSA-9664433 8.446511e-01 0.073 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 8.446511e-01 0.073 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.456979e-01 0.073 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.456979e-01 0.073 0 0
Cardiogenesis R-HSA-9733709 8.524407e-01 0.069 0 0
Notch-HLH transcription pathway R-HSA-350054 8.541098e-01 0.068 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 8.541098e-01 0.068 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 8.541098e-01 0.068 0 0
Fructose metabolism R-HSA-5652084 8.541098e-01 0.068 0 0
LDL clearance R-HSA-8964038 8.541098e-01 0.068 0 0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy R-HSA-9857377 8.541098e-01 0.068 0 0
Activation of GABAB receptors R-HSA-991365 8.564362e-01 0.067 0 0
GABA B receptor activation R-HSA-977444 8.564362e-01 0.067 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.564362e-01 0.067 0 0
SLC transporter disorders R-HSA-5619102 8.572699e-01 0.067 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 8.573608e-01 0.067 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 8.573608e-01 0.067 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 8.573608e-01 0.067 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 8.573608e-01 0.067 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 8.573608e-01 0.067 0 0
Beta oxidation of myristoyl-CoA to lauroyl-CoA R-HSA-77285 8.573608e-01 0.067 0 0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA R-HSA-77305 8.573608e-01 0.067 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 8.573608e-01 0.067 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.573608e-01 0.067 0 0
Conjugation of salicylate with glycine R-HSA-177128 8.573608e-01 0.067 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 8.573608e-01 0.067 0 0
MET activates RAS signaling R-HSA-8851805 8.573608e-01 0.067 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 8.573608e-01 0.067 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 8.573608e-01 0.067 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 8.573608e-01 0.067 0 0
Signaling by LTK R-HSA-9842663 8.573608e-01 0.067 0 0
Interleukin-35 Signalling R-HSA-8984722 8.573608e-01 0.067 0 0
OAS antiviral response R-HSA-8983711 8.573608e-01 0.067 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 8.610291e-01 0.065 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.620311e-01 0.064 0 0
Amino acids regulate mTORC1 R-HSA-9639288 8.625549e-01 0.064 0 0
Glutamate and glutamine metabolism R-HSA-8964539 8.639394e-01 0.064 0 0
Interferon gamma signaling R-HSA-877300 8.643687e-01 0.063 0 0
Formation of the ureteric bud R-HSA-9830674 8.672751e-01 0.062 0 0
Biosynthesis of maresins R-HSA-9018682 8.672751e-01 0.062 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 8.707696e-01 0.060 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 8.736093e-01 0.059 0 0
PDH complex synthesizes acetyl-CoA from PYR R-HSA-9861559 8.737153e-01 0.059 0 0
Processing of SMDT1 R-HSA-8949664 8.737153e-01 0.059 0 0
FGFR1c ligand binding and activation R-HSA-190373 8.737153e-01 0.059 0 0
Interleukin-6 signaling R-HSA-1059683 8.737153e-01 0.059 0 0
Protein-protein interactions at synapses R-HSA-6794362 8.766619e-01 0.057 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 8.793405e-01 0.056 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 8.793405e-01 0.056 0 0
Mitochondrial RNA degradation R-HSA-9836573 8.793405e-01 0.056 0 0
Plasma lipoprotein assembly R-HSA-8963898 8.793405e-01 0.056 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 8.845912e-01 0.053 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 8.845912e-01 0.053 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.849009e-01 0.053 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 8.881955e-01 0.051 0 0
Retrograde neurotrophin signalling R-HSA-177504 8.881955e-01 0.051 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 8.881955e-01 0.051 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 8.881955e-01 0.051 0 0
Hydrolysis of LPC R-HSA-1483115 8.881955e-01 0.051 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.881955e-01 0.051 0 0
HDL assembly R-HSA-8963896 8.881955e-01 0.051 0 0
Zinc transporters R-HSA-435354 8.881955e-01 0.051 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 8.899915e-01 0.051 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 8.903849e-01 0.050 0 0
Cell surface interactions at the vascular wall R-HSA-202733 8.919491e-01 0.050 0 0
Kidney development R-HSA-9830369 8.921914e-01 0.050 0 0
SLC-mediated transport of amino acids R-HSA-9958863 8.921914e-01 0.050 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.938293e-01 0.049 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.938293e-01 0.049 0 0
IRS-mediated signalling R-HSA-112399 8.954230e-01 0.048 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 8.977309e-01 0.047 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.004839e-01 0.046 0 0
TRP channels R-HSA-3295583 9.004839e-01 0.046 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.004839e-01 0.046 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.004839e-01 0.046 0 0
Urea cycle R-HSA-70635 9.004839e-01 0.046 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 9.010160e-01 0.045 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 9.010160e-01 0.045 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 9.010160e-01 0.045 0 0
Protein repair R-HSA-5676934 9.010160e-01 0.045 0 0
Beta oxidation of butanoyl-CoA to acetyl-CoA R-HSA-77352 9.010160e-01 0.045 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 9.010160e-01 0.045 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 9.010160e-01 0.045 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 9.010160e-01 0.045 0 0
Other semaphorin interactions R-HSA-416700 9.010160e-01 0.045 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.023976e-01 0.045 0 0
NGF-stimulated transcription R-HSA-9031628 9.083141e-01 0.042 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 9.097090e-01 0.041 0 0
Signaling by BMP R-HSA-201451 9.097090e-01 0.041 0 0
Insulin processing R-HSA-264876 9.097090e-01 0.041 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 9.103362e-01 0.041 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 9.103362e-01 0.041 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 9.123671e-01 0.040 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 9.123671e-01 0.040 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 9.123671e-01 0.040 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 9.123671e-01 0.040 0 0
Activation of the phototransduction cascade R-HSA-2485179 9.123671e-01 0.040 0 0
Atorvastatin ADME R-HSA-9754706 9.123671e-01 0.040 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 9.123671e-01 0.040 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 9.123671e-01 0.040 0 0
Fructose catabolism R-HSA-70350 9.123671e-01 0.040 0 0
Attachment and Entry R-HSA-9678110 9.123671e-01 0.040 0 0
Stimuli-sensing channels R-HSA-2672351 9.168407e-01 0.038 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 9.176838e-01 0.037 0 0
Telomere Extension By Telomerase R-HSA-171319 9.181278e-01 0.037 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 9.181278e-01 0.037 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.212591e-01 0.036 0 0
PI3K Cascade R-HSA-109704 9.214740e-01 0.036 0 0
Fibronectin matrix formation R-HSA-1566977 9.224171e-01 0.035 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 9.224171e-01 0.035 0 0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids R-HSA-77288 9.224171e-01 0.035 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 9.224171e-01 0.035 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.244779e-01 0.034 0 0
Interleukin-2 family signaling R-HSA-451927 9.244779e-01 0.034 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.258038e-01 0.033 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.265533e-01 0.033 0 0
Heme signaling R-HSA-9707616 9.267634e-01 0.033 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.267634e-01 0.033 0 0
Signaling by PDGF R-HSA-186797 9.267634e-01 0.033 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.275208e-01 0.033 0 0
Maturation of spike protein R-HSA-9694548 9.307543e-01 0.031 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 9.313151e-01 0.031 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 9.313151e-01 0.031 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 9.313151e-01 0.031 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 9.313151e-01 0.031 0 0
Uptake and function of anthrax toxins R-HSA-5210891 9.313151e-01 0.031 0 0
FCGR activation R-HSA-2029481 9.318548e-01 0.031 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.319228e-01 0.031 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.327966e-01 0.030 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.335931e-01 0.030 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.365472e-01 0.028 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.365472e-01 0.028 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.367177e-01 0.028 0 0
IGF1R signaling cascade R-HSA-2428924 9.367548e-01 0.028 0 0
Nucleotide biosynthesis R-HSA-8956320 9.380465e-01 0.028 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.391619e-01 0.027 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 9.391930e-01 0.027 0 0
Presynaptic function of Kainate receptors R-HSA-500657 9.391930e-01 0.027 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.391930e-01 0.027 0 0
FGFR1 ligand binding and activation R-HSA-190242 9.391930e-01 0.027 0 0
Tie2 Signaling R-HSA-210993 9.391930e-01 0.027 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 9.391930e-01 0.027 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.412768e-01 0.026 0 0
RSV-host interactions R-HSA-9833110 9.419087e-01 0.026 0 0
Adipogenesis R-HSA-9843745 9.429887e-01 0.025 0 0
Signaling by WNT in cancer R-HSA-4791275 9.449517e-01 0.025 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 9.461677e-01 0.024 0 0
Amino Acid conjugation R-HSA-156587 9.461677e-01 0.024 0 0
Conjugation of carboxylic acids R-HSA-159424 9.461677e-01 0.024 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.461677e-01 0.024 0 0
Diseases of hemostasis R-HSA-9671793 9.461677e-01 0.024 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 9.461677e-01 0.024 0 0
Other interleukin signaling R-HSA-449836 9.461677e-01 0.024 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 9.502142e-01 0.022 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.503657e-01 0.022 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.523428e-01 0.021 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.523428e-01 0.021 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 9.523428e-01 0.021 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.523428e-01 0.021 0 0
Creatine metabolism R-HSA-71288 9.523428e-01 0.021 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.523428e-01 0.021 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.524468e-01 0.021 0 0
Resolution of D-Loop Structures R-HSA-5693537 9.549941e-01 0.020 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.549941e-01 0.020 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 9.549941e-01 0.020 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.549941e-01 0.020 0 0
Dectin-2 family R-HSA-5621480 9.551954e-01 0.020 0 0
Synthesis of PA R-HSA-1483166 9.551954e-01 0.020 0 0
G-protein activation R-HSA-202040 9.578099e-01 0.019 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 9.578099e-01 0.019 0 0
Phenylalanine metabolism R-HSA-8964208 9.578099e-01 0.019 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.578099e-01 0.019 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.588164e-01 0.018 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.593329e-01 0.018 0 0
Hyaluronan metabolism R-HSA-2142845 9.593329e-01 0.018 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.597977e-01 0.018 0 0
Triglyceride metabolism R-HSA-8979227 9.620187e-01 0.017 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 9.626501e-01 0.017 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 9.626501e-01 0.017 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.626501e-01 0.017 0 0
Androgen biosynthesis R-HSA-193048 9.626501e-01 0.017 0 0
Attachment and Entry R-HSA-9694614 9.626501e-01 0.017 0 0
ECM proteoglycans R-HSA-3000178 9.627884e-01 0.016 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.628670e-01 0.016 0 0
Synthesis of PC R-HSA-1483191 9.628670e-01 0.016 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.632689e-01 0.016 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.632689e-01 0.016 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.644933e-01 0.016 0 0
GABA receptor activation R-HSA-977443 9.650565e-01 0.015 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.650565e-01 0.015 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.669352e-01 0.015 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 9.669352e-01 0.015 0 0
Ethanol oxidation R-HSA-71384 9.669352e-01 0.015 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.669352e-01 0.015 0 0
Aquaporin-mediated transport R-HSA-445717 9.678669e-01 0.014 0 0
Aspirin ADME R-HSA-9749641 9.681650e-01 0.014 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.690654e-01 0.014 0 0
Voltage gated Potassium channels R-HSA-1296072 9.700707e-01 0.013 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.705752e-01 0.013 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.707290e-01 0.013 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.707290e-01 0.013 0 0
Interleukin receptor SHC signaling R-HSA-912526 9.707290e-01 0.013 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.707290e-01 0.013 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.707290e-01 0.013 0 0
Interleukin-20 family signaling R-HSA-8854691 9.707290e-01 0.013 0 0
G alpha (s) signalling events R-HSA-418555 9.711513e-01 0.013 0 0
Formation of the cornified envelope R-HSA-6809371 9.713620e-01 0.013 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.728153e-01 0.012 0 0
CYP2E1 reactions R-HSA-211999 9.740876e-01 0.011 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 9.740876e-01 0.011 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.740876e-01 0.011 0 0
Interleukin-6 family signaling R-HSA-6783589 9.740876e-01 0.011 0 0
Complex IV assembly R-HSA-9864848 9.742760e-01 0.011 0 0
Potassium Channels R-HSA-1296071 9.747192e-01 0.011 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.770611e-01 0.010 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 9.770611e-01 0.010 0 0
Hyaluronan degradation R-HSA-2160916 9.770611e-01 0.010 0 0
Fertilization R-HSA-1187000 9.770611e-01 0.010 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 9.796935e-01 0.009 0 0
Linoleic acid (LA) metabolism R-HSA-2046105 9.796935e-01 0.009 0 0
Sphingolipid catabolism R-HSA-9845614 9.796935e-01 0.009 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.796935e-01 0.009 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.797533e-01 0.009 0 0
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane R-HSA-83936 9.820239e-01 0.008 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 9.820239e-01 0.008 0 0
Intra-Golgi traffic R-HSA-6811438 9.821760e-01 0.008 0 0
Paracetamol ADME R-HSA-9753281 9.823022e-01 0.008 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.823580e-01 0.008 0 0
Extracellular matrix organization R-HSA-1474244 9.836301e-01 0.007 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 9.840870e-01 0.007 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.840870e-01 0.007 0 0
Pyrimidine salvage R-HSA-73614 9.840870e-01 0.007 0 0
Prednisone ADME R-HSA-9757110 9.840870e-01 0.007 0 0
Pyrimidine catabolism R-HSA-73621 9.855462e-01 0.006 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.855462e-01 0.006 0 0
Thyroxine biosynthesis R-HSA-209968 9.859135e-01 0.006 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 9.859135e-01 0.006 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.866396e-01 0.006 0 0
Collagen formation R-HSA-1474290 9.867673e-01 0.006 0 0
Neurotransmitter clearance R-HSA-112311 9.875304e-01 0.005 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 9.875304e-01 0.005 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.878993e-01 0.005 0 0
mitochondrial fatty acid beta-oxidation of saturated fatty acids R-HSA-77286 9.882929e-01 0.005 0 0
Cargo concentration in the ER R-HSA-5694530 9.889618e-01 0.005 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.889618e-01 0.005 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.913507e-01 0.004 0 0
Recycling of bile acids and salts R-HSA-159418 9.913507e-01 0.004 0 0
Metal ion SLC transporters R-HSA-425410 9.914834e-01 0.004 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.923437e-01 0.003 0 0
Heme degradation R-HSA-189483 9.923437e-01 0.003 0 0
Xenobiotics R-HSA-211981 9.925348e-01 0.003 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.925348e-01 0.003 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.932228e-01 0.003 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 9.932228e-01 0.003 0 0
PI Metabolism R-HSA-1483255 9.935779e-01 0.003 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.938599e-01 0.003 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 9.940010e-01 0.003 0 0
Metabolism of steroid hormones R-HSA-196071 9.944340e-01 0.002 0 0
Glycosphingolipid transport R-HSA-9845576 9.946898e-01 0.002 0 0
Phenylalanine and tyrosine metabolism R-HSA-8963691 9.952996e-01 0.002 0 0
Collagen chain trimerization R-HSA-8948216 9.952996e-01 0.002 0 0
Metabolism of folate and pterines R-HSA-196757 9.952996e-01 0.002 0 0
G alpha (i) signalling events R-HSA-418594 9.953729e-01 0.002 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.958395e-01 0.002 0 0
Peptide hormone metabolism R-HSA-2980736 9.959342e-01 0.002 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.967390e-01 0.001 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.967403e-01 0.001 0 0
Tryptophan catabolism R-HSA-71240 9.967403e-01 0.001 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.970957e-01 0.001 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.971147e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.972079e-01 0.001 0 0
G alpha (q) signalling events R-HSA-416476 9.972986e-01 0.001 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.977699e-01 0.001 0 0
Cholesterol biosynthesis R-HSA-191273 9.981424e-01 0.001 0 0
Methylation R-HSA-156581 9.982291e-01 0.001 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.982291e-01 0.001 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.983322e-01 0.001 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.984326e-01 0.001 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.987388e-01 0.001 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.987721e-01 0.001 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.989132e-01 0.000 0 0
PPARA activates gene expression R-HSA-1989781 9.989743e-01 0.000 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.989907e-01 0.000 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.990381e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.990486e-01 0.000 0 0
COPII-mediated vesicle transport R-HSA-204005 9.992209e-01 0.000 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.992465e-01 0.000 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.993025e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.993025e-01 0.000 0 0
Neurotransmitter release cycle R-HSA-112310 9.995098e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.995526e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.995542e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.995903e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.995908e-01 0.000 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.996419e-01 0.000 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.996797e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.996797e-01 0.000 0 0
Interleukin-10 signaling R-HSA-6783783 9.996797e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.997009e-01 0.000 0 0
Sialic acid metabolism R-HSA-4085001 9.997164e-01 0.000 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.997490e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.997702e-01 0.000 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.997710e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.997779e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.997779e-01 0.000 0 0
Collagen degradation R-HSA-1442490 9.997779e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.997845e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.997874e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.998163e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.998260e-01 0.000 0 0
Digestion and absorption R-HSA-8963743 9.998260e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.998833e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.998849e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.999056e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999257e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.999260e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.999346e-01 0.000 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 9.999547e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999567e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999611e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999623e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.999623e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.999754e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.999787e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999846e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999867e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999889e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999942e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999950e-01 0.000 0 0
Regulation of Complement cascade R-HSA-977606 9.999992e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999996e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999996e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999997e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999999e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.999999e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999999e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999999e-01 0.000 0 0
Complement cascade R-HSA-166658 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
Sensory perception of taste R-HSA-9717189 1.000000e+00 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
O-linked glycosylation R-HSA-5173105 1.000000e+00 0.000 0 0
Diseases of glycosylation R-HSA-3781865 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways