YSK1

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0MZ66 T455 Sugiyama SHTN1 KIAA1598 KPESSKGCEsAVDELKGILGtLNKSTSSRsLKsLDPENsEt
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A6NMY6 S26 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI
O00303 T119 Sugiyama EIF3F EIF3S5 LASIVDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPH
O00303 T123 Sugiyama EIF3F EIF3S5 VDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPHNEsE
O00506 S12 Sugiyama STK25 SOK1 YSK1 _________MAHLRGFANQHsRVDPEELFTKLDRIGKGsFG
O00506 S133 Sugiyama STK25 SOK1 YSK1 EETYIATILREILKGLDYLHsERKIHRDIKAANVLLsEQGD
O00506 S30 Sugiyama STK25 SOK1 YSK1 QHsRVDPEELFTKLDRIGKGsFGEVYKGIDNHTKEVVAIKI
O00506 S341 Sugiyama STK25 SOK1 YSK1 FPPTIRPSPHSKLHKGtALHssQKPAEPVKRQPRSQCLSTL
O00506 S342 Sugiyama STK25 SOK1 YSK1 PPTIRPSPHSKLHKGtALHssQKPAEPVKRQPRSQCLSTLV
O00506 S391 Sugiyama STK25 SOK1 YSK1 EKHKQSGGSVGALEELENAFsLAEEsCPGISDKLMVHLVER
O00506 S396 Sugiyama STK25 SOK1 YSK1 SGGSVGALEELENAFsLAEEsCPGISDKLMVHLVERVQRFS
O00506 T166 Sugiyama STK25 SOK1 YSK1 VLLsEQGDVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEV
O00506 T168 Sugiyama STK25 SOK1 YSK1 LsEQGDVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEVIK
O00506 T174 GPS6|EPSD STK25 SOK1 YSK1 VKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEVIKQSAYDF
O00506 T337 Sugiyama STK25 SOK1 YSK1 PIWTFPPTIRPSPHSKLHKGtALHssQKPAEPVKRQPRSQC
O14818 S150 Sugiyama PSMA7 HSPC SALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVRE
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43390 T141 Sugiyama HNRNPR HNRPR GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP
O43707 S507 Sugiyama ACTN4 DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID
O43707 T359 Sugiyama ACTN4 RRVHKPPKVQEKCQLEINFNtLQtKLRLSNRPAFMPSEGKM
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43707 T509 Sugiyama ACTN4 HNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAIDQL
O43707 T69 Sugiyama ACTN4 EKQQRKTFTAWCNsHLRKAGtQIENIDEDFRDGLKLMLLLE
O60361 T88 Sugiyama NME2P1 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O60506 T138 Sugiyama SYNCRIP HNRPQ NSAP1 GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP
O60716 S230 Sugiyama CTNND1 KIAA0384 PDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRA
O60716 S232 Sugiyama CTNND1 KIAA0384 GysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRAPs
O75116 T967 Sugiyama ROCK2 KIAA0619 ELEIKEMMARHKQELTEKDAtIAsLEETNRtLtSDVANLAN
O75116 T977 Sugiyama ROCK2 KIAA0619 HKQELTEKDAtIAsLEETNRtLtSDVANLANEKEELNNKLK
O75821 S217 Sugiyama EIF3G EIF3S4 PGELEPVQAtQNKtGKYVPPsLRDGAsRRGESMQPNRRADD
O75821 T206 Sugiyama EIF3G EIF3S4 LGLstGEKEKLPGELEPVQAtQNKtGKYVPPsLRDGAsRRG
O75821 T240 Sugiyama EIF3G EIF3S4 DGAsRRGESMQPNRRADDNAtIRVtNLSEDTRETDLQELFR
O95071 T119 Sugiyama UBR5 EDD EDD1 HYD KIAA0896 GRTSRPGRTSDsPWFLsGSEtLGRLAGNTLGSRWSsGVGGs
O95218 T50 Sugiyama ZRANB2 ZIS ZNF265 SCNRCGREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQ
O95218 T55 Sugiyama ZRANB2 ZIS ZNF265 GREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQCKTCs
O95373 T997 Sugiyama IPO7 RANBP7 yQALTHGLNEEQRKQLQDIAtLADQRRAAHESKMIEKHGGY
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95757 S587 Sugiyama HSPA4L APG1 HSPH3 OSP94 RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00390 T507 Sugiyama GSR GLUR GRD1 MLQGFAVAVKMGATKADFDNtVAIHPtssEELVtLR_____
P00390 T520 Sugiyama GSR GLUR GRD1 TKADFDNtVAIHPtssEELVtLR__________________
P00491 T177 Sugiyama PNP NP DRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVAG
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 T376 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG
P00558 T378 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02786 T143 Sugiyama TFRC yWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAGsQKDE
P02786 T336 Sugiyama TFRC FNHTQFPPSRSSGLPNIPVQtISRAAAEKLFGNMEGDCPSD
P04040 S515 Sugiyama CAT ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________
P04040 T43 Sugiyama CAT KADVLttGAGNPVGDKLNVItVGPRGPLLVQDVVFTDEMAH
P04040 T434 Sugiyama CAT QQPSALEHSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEE
P04040 T511 Sugiyama CAT SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T124 Sugiyama ALDOA ALDA VVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGAD
P04083 T223 Sugiyama ANXA1 ANX1 LPC1 ARALyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKY
P04083 T226 Sugiyama ANXA1 ANX1 LPC1 LyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKYSKH
P04083 T64 Sugiyama ANXA1 ANX1 LPC1 PssDVAALHKAIMVKGVDEAtIIDILtKRNNAQRQQIKAAY
P04083 T70 Sugiyama ANXA1 ANX1 LPC1 ALHKAIMVKGVDEAtIIDILtKRNNAQRQQIKAAYLQEtGK
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S151 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV
P04406 S210 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG
P04406 T154 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEGL
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04632 T143 Sugiyama CAPNS1 CAPN4 CAPNS ILNKVVTRHPDLKTDGFGIDtCRSMVAVMDSDTTGKLGFEE
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S410 Sugiyama KRT8 CYK8 TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P06703 S46 Sugiyama S100A6 CACY KHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRNKDQ
P06703 T43 Sugiyama S100A6 CACY EGDKHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRN
P06733 S14 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 T55 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP
P06744 S247 Sugiyama GPI EWFLQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFW
P06744 T250 Sugiyama GPI LQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFWDWV
P06748 S260 Sugiyama NPM1 NPM GPssVEDIKAKMQAsIEKGGsLPKVEAKFINyVKNCFRMtD
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T276 Sugiyama LDHB SVADLIESMLKNLSRIHPVStMVKGMYGIENEVFLSLPCIL
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07355 S26 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07814 S330 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KHRKNPIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGC
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 S739 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07814 T1506 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 LCELQPGAKCVCGKNPAKyytLFGRsy______________
P07814 T745 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVR
P07858 T218 Sugiyama CTSB CPSB CTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSEKD
P07858 T95 Sugiyama CTSB CPSB TEDLKLPAsFDAREQWPQCPtIKEIRDQGSCGSCWAFGAVE
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S169 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA TVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILH
P07900 S476 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S63 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P07900 S641 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD
P07900 S72 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQDRtLtIV
P07900 T109 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LtIVDtGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
P07900 T171 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILHLK
P07900 T624 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE
P07900 T645 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL
P07900 Y61 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KEIFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLI
P08195 S253 Sugiyama SLC3A2 MDU1 FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA
P08195 T321 Sugiyama SLC3A2 MDU1 SIRVILDLTPNYRGENSWFStQVDtVATKVKDALEFWLQAG
P08195 T325 Sugiyama SLC3A2 MDU1 ILDLTPNYRGENSWFStQVDtVATKVKDALEFWLQAGVDGF
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S164 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILH
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S58 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238 S67 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERtLtLV
P08238 T104 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LtLVDtGIGMtKADLINNLGtIAKSGtKAFMEALQAGADIS
P08238 T166 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILHLK
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08238 T637 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08238 Y56 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEIFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDII
P08238 Y619 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P08758 T33 Sugiyama ANXA5 ANX5 ENX2 PP4 PGFDERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEI
P08758 T40 Sugiyama ANXA5 ANX5 ENX2 PP4 DAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTL
P08758 T43 Sugiyama ANXA5 ANX5 ENX2 PP4 tLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTLFGR
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09211 T62 Sugiyama GSTP1 FAEES3 GST3 GsLKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGK
P09211 T68 Sugiyama GSTP1 FAEES3 GST3 CLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQEAA
P09211 Y64 Sugiyama GSTP1 FAEES3 GST3 LKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQ
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09651 S360 Sugiyama HNRNPA1 HNRPA1 PyGGGGQyFAKPRNQGGyGGssssssyGsGRRF________
P09651 S363 Sugiyama HNRNPA1 HNRPA1 GGGQyFAKPRNQGGyGGssssssyGsGRRF___________
P09651 S368 Sugiyama HNRNPA1 HNRPA1 FAKPRNQGGyGGssssssyGsGRRF________________
P09651 Y357 Sugiyama HNRNPA1 HNRPA1 ssGPyGGGGQyFAKPRNQGGyGGssssssyGsGRRF_____
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7 T334 Sugiyama TUBA3C TUBA2 ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
P0DPH7 T51 Sugiyama TUBA3C TUBA2 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P0DPH7 T56 Sugiyama TUBA3C TUBA2 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10644 S77 PSP PRKAR1A PKR1 PRKAR1 TSE1 LEKEEAKQIQNLQKAGtRtDsREDEIsPPPPNPVVKGRRRR
P10644 S83 PSP PRKAR1A PKR1 PRKAR1 TSE1 KQIQNLQKAGtRtDsREDEIsPPPPNPVVKGRRRRGAIsAE
P10809 S453 Sugiyama HSPD1 HSP60 EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P10809 T206 Sugiyama HSPD1 HSP60 IsDAMKKVGRKGVITVKDGKtLNDELEIIEGMKFDRGyIsP
P10809 T231 Sugiyama HSPD1 HSP60 LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P11142 S153 Sugiyama HSPA8 HSC70 HSP73 HSPA10 AyLGKtVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNVLRII
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 T158 Sugiyama HSPA8 HSC70 HSP73 HSPA10 tVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11586 S129 Sugiyama MTHFD1 MTHFC MTHFD INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP
P11586 T527 Sugiyama MTHFD1 MTHFC MTHFD PTTLtDEEINRFARLDIDPEtITWQRVLDTNDRFLRKITIG
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12277 S128 Sugiyama CKB CKBB TDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsR
P12277 S164 Sugiyama CKB CKBB PHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAEQ
P12814 T340 Sugiyama ACTN1 RRLHKPPKVQEKCQLEINFNtLQtKLRLsNRPAFMPsEGRM
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639 T484 Sugiyama EEF2 EF2 VPCGNIVGLVGVDQFLVKtGtIttFEHAHNMRVMKFsVsPV
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P13929 T19 Sugiyama ENO3 __MAMQKIFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGA
P13929 T26 Sugiyama ENO3 IFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGAstGIyEA
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P14314 S445 Sugiyama PRKCSH G19P1 YRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKy
P14314 S451 Sugiyama PRKCSH G19P1 KLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKyEQGtGC
P14314 T115 Sugiyama PRKCSH G19P1 GVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQQMAEVtR
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S77 Sugiyama PKM OIP3 PK2 PK3 PKM2 sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs
P14618 T454 Sugiyama PKM OIP3 PK2 PK3 PKM2 SGRSAHQVARYRPRAPIIAVtRNPQtARQAHLYRGIFPVLC
P14618 T459 Sugiyama PKM OIP3 PK2 PK3 PKM2 HQVARYRPRAPIIAVtRNPQtARQAHLYRGIFPVLCKDPVQ
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14618 T80 Sugiyama PKM OIP3 PK2 PK3 PKM2 tLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAs
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P14625 T450 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRKTLD
P15153 T161 Sugiyama RAC2 QGLALAKEIDSVKyLECsALtQRGLKtVFDEAIRAVLCPQP
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15531 T103 Sugiyama NME1 NDPKA NM23 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P15880 S190 Sugiyama RPS2 RPS4 WGNKIGKPHTVPCKVTGRCGsVLVRLIPAPRGtGIVsAPVP
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P15880 T285 Sugiyama RPS2 RPS4 PyQEFtDHLVKtHtRVsVQRtQAPAVATt____________
P16083 T59 Sugiyama NQO2 NMOR2 VSDLyAMNLEPRATDKDITGtLSNPEVFNyGVEtHEAyKQR
P16083 T72 Sugiyama NQO2 NMOR2 TDKDITGtLSNPEVFNyGVEtHEAyKQRsLAsDITDEQKKV
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17174 S106 Sugiyama GOT1 RLALGDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNG
P17174 T110 Sugiyama GOT1 GDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNGTNNK
P18124 T17 Sugiyama RPL7 ____MEGVEEKKKEVPAVPEtLKKKRRNFAELKIKRLRKKF
P18124 T170 Sugiyama RPL7 VNELIyKRGYGKINKKRIALtDNALIARSLGKyGIICMEDL
P18621 T79 Sugiyama RPL17 PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S595 Sugiyama NCL FVKGLsEDttEEtLKEsFDGsVRARIVTDRETGssKGFGFV
P19338 T587 Sugiyama NCL RSQPSKTLFVKGLsEDttEEtLKEsFDGsVRARIVTDRETG
P19338 Y463 Sugiyama NCL EKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsG
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20618 S162 Sugiyama PSMB1 PSC5 DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG
P20674 T105 Sugiyama COX5A EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY
P22090 S204 Sugiyama RPS4Y1 RPS4Y PRO2646 IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22314 T600 Sugiyama UBA1 A1S9T UBE1 ARMYMDRRCVYYRKPLLESGtLGtKGNVQVVIPFLTESySS
P22314 T603 Sugiyama UBA1 A1S9T UBE1 YMDRRCVYYRKPLLESGtLGtKGNVQVVIPFLTESySSSQD
P22392 T103 Sugiyama NME2 NM23B VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P22626 S201 Sugiyama HNRNPA2B1 HNRPA2B1 NAEVRKALsRQEMQEVQssRsGRGGNFGFGDsRGGGGNFGP
P23193 T256 Sugiyama TCEA1 GTF2S TFIIS MRKNLTKEAIREHQMAKTGGtQTDLFtCGKCKKKNCTYTQV
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23381 T364 Sugiyama WARS1 IFI53 WARS WRS QGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRDtI
P23396 T242 Sugiyama RPS3 OK/SW-cl.26 PIsEQKGGKPEPPAMPQPVPtA___________________
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23526 T157 Sugiyama AHCY SAHH NLIHTKYPQLLPGIRGIsEEtTTGVHNLyKMMANGILKVPA
P23526 T185 Sugiyama AHCY SAHH yKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGIKR
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P24752 T220 Sugiyama ACAT1 ACAT MAT TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV
P24752 Y219 Sugiyama ACAT1 ACAT MAT NTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVt
P25205 S34 Sugiyama MCM3 EAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVNDL
P25205 T240 Sugiyama MCM3 ILDDDLVDKAKPGDRVQVVGtYRCLPGKKGGYTSGTFRTVL
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26639 T248 Sugiyama TARS1 TARS AMFKYNKFKCRILNEKVNtPtttVyRCGPLIDLCRGPHVRH
P26639 T249 Sugiyama TARS1 TARS MFKYNKFKCRILNEKVNtPtttVyRCGPLIDLCRGPHVRHT
P26639 T657 Sugiyama TARS1 TARS VRQQFHDAKFMADIDLDPGCtLNKKIRNAQLAQYNFILVVG
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27695 S66 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 EDPPDQKtsPsGKPAtLKICsWNVDGLRAWIKKKGLDWVKE
P27797 S35 Sugiyama CALR CRTC AVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGK
P27797 S40 Sugiyama CALR CRTC AVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGKFyGDE
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P30040 T43 Sugiyama ERP29 C12orf8 ERP28 LLSAPHGGSGLHTKGALPLDtVtFyKVIPKSKFVLVKFDtQ
P30043 S198 Sugiyama BLVRB FLR SCAN KHDLGHFMLRCLttDEyDGHstyPsHQyQ____________
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 T135 Sugiyama RPL12 QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30086 T167 Sugiyama PEBP1 PBP PEBP GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P31327 S898 Sugiyama CPS1 LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31327 T900 Sugiyama CPS1 KMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKC
P31327 T903 Sugiyama CPS1 DILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKCLGL
P31942 S298 Sugiyama HNRNPH3 HNRPH3 GGsGMGGYGRDGMDNQGGyGsVGRMGMGNNysGGyGtPDGL
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948 T243 Sugiyama STIP1 KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT
P31949 T33 Sugiyama S100A11 MLN70 S100C CIESLIAVFQKYAGKDGyNytLsKtEFLsFMNTELAAFTKN
P32969 T186 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 TVKNKDIRKFLDGIyVsEKGtVQQADE______________
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P35579 S1892 Sugiyama MYH9 LKQLKRQLEEAEEEAQRANAsRRKLQRELEDAtEtADAMNR
P35579 T1151 Sugiyama MYH9 EKQKRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNI
P35579 T1208 Sugiyama MYH9 QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE
P35609 T347 Sugiyama ACTN2 RRKHKPPKVQEKCQLEINFNtLQtKLRISNRPAFMPSEGKM
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36578 S66 Sugiyama RPL4 RPL1 KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T266 Sugiyama RPL4 RPL1 VGRFCIWtEsAFRKLDELyGtWRKAAsLKsNyNLPMHKMIN
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578 T69 Sugiyama RPL4 RPL1 RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P36871 S483 Sugiyama PGM1 DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37108 T45 Sugiyama SRP14 sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37108 Y27 Sugiyama SRP14 EQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGtVE
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P38117 T172 Sugiyama ETFB FP585 QVTLEGDKLKVEREIDGGLEtLRLKLPAVVTADLRLNEPRy
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T192 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 MKMKEtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIs
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P38646 Y196 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 EtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNV
P39019 S59 Sugiyama RPS19 LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019 S93 Sugiyama RPS19 GsMTKIYGGRQRNGVMPsHFsRGsKsVARRVLQALEGLKMV
P39019 T36 Sugiyama RPS19 RALAAFLKKSGKLKVPEWVDtVKLAKHKELAPyDENWFytR
P39019 T55 Sugiyama RPS19 DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019 T60 Sugiyama RPS19 AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40429 T153 Sugiyama RPL13A RKFAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQ
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P40926 T224 Sugiyama MDH2 TIIPLISQCtPKVDFPQDQLtALtGRIQEAGtEVVKAKAGA
P40926 T227 Sugiyama MDH2 PLISQCtPKVDFPQDQLtALtGRIQEAGtEVVKAKAGAGsA
P41091 T22 Sugiyama EIF2S3 EIF2G AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
P41091 T41 Sugiyama EIF2S3 EIF2G ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
P41091 T46 Sugiyama EIF2S3 EIF2G tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHt
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42766 T59 Sugiyama RPL35 GAASKLsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyK
P42766 T64 Sugiyama RPL35 LsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyKPLDLR
P46060 S24 Sugiyama RANGAP1 KIAA1835 SD EDIAKLAETLAKTQVAGGQLsFKGKSLKLNTAEDAKDVIKE
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46777 S230 Sugiyama RPL5 MSTP030 yLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAHAAIREN
P46777 T177 Sugiyama RPL5 MSTP030 NKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRK
P46777 Y226 Sugiyama RPL5 MSTP030 DyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAHAA
P46778 T29 Sugiyama RPL21 RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ
P46778 Y30 Sugiyama RPL21 GTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQK
P46779 T89 Sugiyama RPL28 GQRKPAtsyVRttINKNARAtLsSIRHMIRKNKYRPDLRMA
P46782 S75 Sugiyama RPS5 RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P47756 T186 Sugiyama CAPZB HYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDC
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P49327 T1999 Sugiyama FASN FAS LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF
P49368 T373 Sugiyama CCT3 CCTG TRIC5 KKIGDEYFTFITDCKDPKACtILLRGAsKEILSEVERNLQD
P49368 T459 Sugiyama CCT3 CCTG TRIC5 AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG
P49589 S34 Sugiyama CARS1 CARS VQPQWsPPAGtQPCRLHLyNsLtRNKEVFIPQDGKKVTWYC
P49773 T17 Sugiyama HINT1 HINT PKCI1 PRKCNH1 ____MADEIAKAQVARPGGDtIFGKIIRKEIPAKIIFEDDR
P50395 T205 Sugiyama GDI2 RABGDIB TGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsPYL
P50454 S139 Sugiyama SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS
P50990 T398 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 RGstDNLMDDIERAVDDGVNtFKVLTRDKRLVPGGGAtEIE
P50991 S51 Sugiyama CCT4 CCTD SRB AQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtIt
P50991 T50 Sugiyama CCT4 CCTD SRB PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI
P50991 T69 Sugiyama CCT4 CCTD SRB RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR
P50991 T76 Sugiyama CCT4 CCTD SRB GMDKMIQDGKGDVtItNDGAtILKQMQVLHPAARMLVELSK
P51116 S601 Sugiyama FXR2 FMR1L2 RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ
P51116 T610 Sugiyama FXR2 FMR1L2 RRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLER
P51149 T168 Sugiyama RAB7A RAB7 NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE
P51532 S1382 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE
P51858 T94 Sugiyama HDGF HMG1L2 GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P53621 T821 Sugiyama COPA IMPLDTNWPLLTVSKGFFEGtIAsKGKGGALAADIDIDTVG
P54136 T383 Sugiyama RARS1 RARS IVFVPGCSIPLTIVKsDGGytyDtSDLAAIKQRLFEEKADM
P54136 T386 Sugiyama RARS1 RARS VPGCSIPLTIVKsDGGytyDtSDLAAIKQRLFEEKADMIIY
P54136 Y384 Sugiyama RARS1 RARS VFVPGCSIPLTIVKsDGGytyDtSDLAAIKQRLFEEKADMI
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P55036 S358 Sugiyama PSMD4 MCB1 VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55209 T269 Sugiyama NAP1L1 NRP GPEIMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVT
P55209 T272 Sugiyama NAP1L1 NRP IMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVTKTV
P55209 T64 Sugiyama NAP1L1 NRP QNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNL
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P55854 S27 Sugiyama SUMO3 SMT3A SMT3H1 KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P56192 S812 Sugiyama MARS1 MARS GHQIGTVSPLFQKLENDQIEsLRQRFGGGQAKtsPKPAVVE
P56192 T710 Sugiyama MARS1 MARS QHYHQLLEKVRIRDALRSILtISRHGNQyIQVNEPWKRIKG
P57721 S59 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT EGGLNVTLTIRLLMHGKEVGsIIGKKGETVKKMREESGARI
P57723 S31 Sugiyama PCBP4 EPELSITLTLRMLMHGKEVGsIIGKKGETVKRIREQSSARI
P60174 S195 Sugiyama TPI1 TPI KtATPQQAQEVHEKLRGWLKsNVsDAVAQstRIIyGGsVtG
P60174 S204 Sugiyama TPI1 TPI EVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQ
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T214 Sugiyama TPI1 TPI KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T28 Sugiyama TPI1 TPI FVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVVCAPPtAy
P60174 T38 Sugiyama TPI1 TPI RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP
P60174 T46 Sugiyama TPI1 TPI IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN
P60174 T90 Sugiyama TPI1 TPI VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 T85 Sugiyama MYL6 LDFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVM
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T202 Sugiyama ACTB GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60763 T161 Sugiyama RAC3 QGLAMAREIGSVKyLECsALtQRGLKtVFDEAIRAVLCPPP
P60842 T80 Sugiyama EIF4A1 DDX2A EIF4A QRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDLKA
P61204 S147 Sugiyama ARF3 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P61221 Y594 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 RPRINKLNsIKDVEQKKsGNyFFLDD_______________
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61254 T93 Sugiyama RPL26 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
P61254 T94 Sugiyama RPL26 YRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDKD
P61313 S100 Sugiyama RPL15 EC45 TCBAP0781 tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW
P61313 S97 Sugiyama RPL15 EC45 TCBAP0781 KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN
P61313 Y59 Sugiyama RPL15 EC45 TCBAP0781 APRPTRPDKARRLGYKAKQGyVIyRIRVRRGGRKRPVPKGA
P61353 T94 Sugiyama RPL27 VyNyNHLMPtRysVDIPLDKtVVNKDVFRDPALKRKARREA
P61513 S21 Sugiyama RPL37A MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQHAKYTCSF
P61513 Y14 Sugiyama RPL37A _______MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQH
P61604 S64 Sugiyama HSPE1 AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD
P61604 T45 Sugiyama HSPE1 TVTKGGIMLPEKSQGKVLQAtVVAVGsGsKGKGGEIQPVsV
P61927 T82 Sugiyama RPL37 GRMRHLKIVYRRFRHGFREGttPKPKRAAVAASSss_____
P61927 T83 Sugiyama RPL37 RMRHLKIVYRRFRHGFREGttPKPKRAAVAASSss______
P61956 S28 Sugiyama SUMO2 SMT3B SMT3H2 EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62081 T172 Sugiyama RPS7 RLIKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEF
P62191 T56 Sugiyama PSMC1 KKKKTKGPDAASKLPLVtPHtQCRLKLLKLERIKDYLLMEE
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62241 S66 Sugiyama RPS8 OK/SW-cl.83 VRVRGGNKKYRALRLDVGNFsWGSECCTRKTRIIDVVyNAS
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62266 T34 Sugiyama RPS23 RSHRRDQKWHDKQYKKAHLGtALKANPFGGAsHAKGIVLEK
P62273 S9 Sugiyama RPS29 ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 S67 Sugiyama RPS11 PKEAIEGtyIDKKCPFTGNVsIRGRILsGVVTKMKMQRTIV
P62280 T15 Sugiyama RPS11 ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62280 T28 Sugiyama RPS11 RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62316 T40 Sugiyama SNRPD2 SNRPD1 EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62424 T142 Sugiyama RPL7A SURF-3 SURF3 AAGKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVD
P62424 T144 Sugiyama RPL7A SURF-3 SURF3 GKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVDPI
P62424 T145 Sugiyama RPL7A SURF-3 SURF3 KGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVDPIE
P62424 T84 Sugiyama RPL7A SURF-3 SURF3 QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP
P62701 S204 Sugiyama RPS4X CCG2 RPS4 SCAR tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62750 S43 Sugiyama RPL23A KAKKAVLKGVHSHKKKKIRtsPTFRRPKTLRLRRQPKYPRK
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62753 T127 Sugiyama RPS6 OK/SW-cl.2 SVLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNL
P62753 T128 Sugiyama RPS6 OK/SW-cl.2 VLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNLs
P62826 T21 Sugiyama RAN ARA24 OK/SW-cl.81 MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62826 T24 Sugiyama RAN ARA24 OK/SW-cl.81 QGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVATLG
P62826 T25 Sugiyama RAN ARA24 OK/SW-cl.81 GEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGV
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62847 S78 Sugiyama RPS24 FGFRTHFGGGKttGFGMIyDsLDyAKKNEPKHRLARHGLYE
P62888 T83 Sugiyama RPL30 yAMLAKtGVHHysGNNIELGtACGKyyRVCtLAIIDPGDsD
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62899 Y25 Sugiyama RPL31 KKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRA
P62906 S64 Sugiyama RPL10A NEDD6 QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 T143 Sugiyama RPL8 RGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANR
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 S51 Sugiyama PPIA CYPA KtAENFRALSTGEKGFGYKGsCFHRIIPGFMCQGGDFtRHN
P62942 T15 Sugiyama FKBP1A FKBP1 FKBP12 ______MGVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGK
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 T147 Sugiyama RPS27A UBA80 UBCEP1 GAGVFMAsHFDRHyCGKCCLtyCFNKPEDK___________
P63000 T161 Sugiyama RAC1 TC25 MIG5 QGLAMAKEIGAVKyLECsALtQRGLKtVFDEAIRAVLCPPP
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63104 S58 iPTMNet|EPSD YWHAZ NEERNLLsVAyKNVVGARRssWRVVssIEQKTEGAEKKQQM
P63167 S21 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAH
P63167 T26 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T202 Sugiyama ACTG1 ACTG GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T22 Sugiyama EEF1A1 EEF1A EF1A LENG7 GKEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKF
P68104 T261 Sugiyama EEF1A1 EEF1A EF1A LENG7 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 T334 Sugiyama TUBA1B ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG
P68363 T51 Sugiyama TUBA1B QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P68363 T56 Sugiyama TUBA1B MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371 T103 Sugiyama CCT2 99D8.1 CCTB VLVDMSRVQDDEVGDGTTsVtVLAAELLREAESLIAKKIHP
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P78417 S23 Sugiyama GSTO1 GSTTLP28 GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK
P78417 Y27 Sugiyama GSTO1 GSTTLP28 RsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLKAKGI
P83731 S7 Sugiyama RPL24 ______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731 T52 Sugiyama RPL24 LNAKCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRT
P83731 Y55 Sugiyama RPL24 KCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRTRRA
P84077 S147 Sugiyama ARF1 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P84098 S12 Sugiyama RPL19 _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P99999 T50 Sugiyama CYCS CYC GPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEYLE
Q00341 T729 Sugiyama HDLBP HBP VGL VEKAKKQLLHLAEEKQTKSFtVDIRAKPEYHKFLIGKGGGK
Q00839 T532 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 TWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtGKL
Q01082 S1388 Sugiyama SPTBN1 SPTB2 TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy
Q01105 S165 Sugiyama SET PyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQ
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q01518 T165 Sugiyama CAP1 CAP AMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVKA
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q02543 T101 Sugiyama RPL18A WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02543 Y110 Sugiyama RPL18A tHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIMKVE
Q02878 T118 Sugiyama RPL6 TXREB1 GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR
Q02878 T213 Sugiyama RPL6 TXREB1 FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q02878 Y216 Sugiyama RPL6 TXREB1 AtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIFDtE
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T22 Sugiyama EEF1A2 EEF1AL STN GKEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKF
Q05639 T261 Sugiyama EEF1A2 EEF1AL STN PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06830 T111 Sugiyama PRDX1 PAGA PAGB TDPX2 PKKQGGLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLF
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020 T39 Sugiyama RPL18 KSQDIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRP
Q07020 T42 Sugiyama RPL18 DIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRPPLs
Q07020 T79 Sugiyama RPL18 PPLsLsRMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLK
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q08043 T354 Sugiyama ACTN3 RRLHKPPRIQEKCQLEINFNtLQtKLRLSHRPAFMPSEGKL
Q12906 T188 Sugiyama ILF3 DRBF MPHOSPH4 NF90 TIHLTSPVVREEMEKVLAGEtLsVNDPPDVLDRQKCLAALA
Q12965 S943 Sugiyama MYO1E MYO1C GLPKNSRPTRRNttQNtGySsGtQNANyPVRAAPPPPGyHQ
Q13136 T572 Sugiyama PPFIA1 LIP1 LRRPQKGRLAALRDEPSKVQtLNEQDWERAQQASVLANVAQ
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13561 T315 Sugiyama DCTN2 DCTN50 KHKASVEDADTQSKVHQLyEtIQRWsPIASTLPELVQRLVT
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S988 Sugiyama EIF3A EIF3S10 KIAA0139 PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN
Q14152 T1378 Sugiyama EIF3A EIF3S10 KIAA0139 AEKDREsLRRTKNEtDEDGWttVRR________________
Q14152 T1379 Sugiyama EIF3A EIF3S10 KIAA0139 EKDREsLRRTKNEtDEDGWttVRR_________________
Q14157 T23 Sugiyama UBAP2L KIAA0144 NICE4 TSVGTNRARGNWEQPQNQNQtQHKQRPQATAEQIRLAQMIS
Q14240 T81 Sugiyama EIF4A2 DDX2B EIF4F QRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEFKE
Q14247 S113 Sugiyama CTTN EMS1 DRMDKsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVD
Q14498 T175 Sugiyama RBM39 HCC1 RNPC2 VFCMQLAARIRPRDLEEFFStVGKVRDVRMISDRNSRRSKG
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 S169 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 TVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILH
Q14568 T109 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LTIVDTGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
Q14568 T171 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 ITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILHLK
Q14677 T271 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 KDEEETVTTKHIHItQATEttttRHKRTANPsKtIDLGAAA
Q14683 S514 Sugiyama SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 SSRQQRKAEIMESIKRLYPGsVyGRLIDLCQPTQKKYQIAV
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15021 S1310 Sugiyama NCAPD2 CAPD2 CNAP1 KIAA0159 RACHTRGLDGIKELEIGQAGsQRAPsAKKPSTGSRyQPLAs
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15181 T245 Sugiyama PPA1 IOPPP PP DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA
Q15181 T246 Sugiyama PPA1 IOPPP PP HWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDAL
Q15185 S85 Sugiyama PTGES3 P23 TEBP KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN
Q15293 T144 Sugiyama RCN1 RCN WKDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtF
Q15293 T163 Sugiyama RCN1 RCN AtyGyyLGNPAEFHDssDHHtFKKMLPRDERRFKAADLNGD
Q15365 S27 Sugiyama PCBP1 ESGLNVTLTIRLLMHGKEVGsIIGKKGESVKRIREEsGARI
Q15366 S27 Sugiyama PCBP2 EGGLNVTLTIRLLMHGKEVGsIIGKKGESVKKMREESGARI
Q15369 T41 Sugiyama ELOC TCEB1 LISSDGHEFIVKREHALtsGtIKAMLSGPGQFAENETNEVN
Q15459 S508 Sugiyama SF3A1 SAP114 IGEEEIQKPEEKVTWDGHsGsMARTQQAAQANITLQEQIEA
Q15560 T254 Sugiyama TCEA2 IRKAMTKEAIREHQMARTGGtQTDLFtCGKCRKKNCTYTQV
Q15813 T56 Sugiyama TBCE WLGVEWDNPERGKHDGSHEGtVyFKCRHPTGGSFIRPNKVN
Q15813 Y58 Sugiyama TBCE GVEWDNPERGKHDGSHEGtVyFKCRHPTGGSFIRPNKVNFG
Q16181 T318 Sugiyama SEPTIN7 CDC10 SEPT7 KDVTNNVHyENyRSRKLAAVtyNGVDNNKNKGQLtKsPLAQ
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q16775 T291 Sugiyama HAGH GLO2 HAGH1 PFMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD___
Q16775 T292 Sugiyama HAGH GLO2 HAGH1 FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____
Q27J81 T1206 Sugiyama INF2 C14orf151 C14orf173 DtsLDKsFsEDAVtDssGsGtLPRARGRASKGTGKRRKKRP
Q2VIR3 T22 Sugiyama EIF2S3B AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
Q2VIR3 T41 Sugiyama EIF2S3B ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
Q2VIR3 T46 Sugiyama EIF2S3B tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHT
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3ZCM7 S75 Sugiyama TUBB8 SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC
Q3ZCM7 T72 Sugiyama TUBB8 NEASGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIF
Q53EL6 S49 Sugiyama PDCD4 H731 ENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNssR
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q58FF6 S34 Sugiyama HSP90AB4P IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S58 Sugiyama HSP90AB3P HSP90BC IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF7 S67 Sugiyama HSP90AB3P HSP90BC ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERTLALV
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q58FF7 Y492 Sugiyama HSP90AB3P HSP90BC TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR
Q58FF7 Y56 Sugiyama HSP90AB3P HSP90BC EEIFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FF8 S58 Sugiyama HSP90AB2P HSP90BB IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 S67 Sugiyama HSP90AB2P HSP90BB ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQEHTLTLV
Q58FF8 T104 Sugiyama HSP90AB2P HSP90BB LTLVDTGIGMTKADLINNLGtIAKFQDQTEYLEEMQVKEVV
Q58FF8 Y56 Sugiyama HSP90AB2P HSP90BB KEIFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q5VTE0 T22 Sugiyama EEF1A1P5 EEF1AL3 GKEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKF
Q5VTE0 T261 Sugiyama EEF1A1P5 EEF1AL3 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6EEV6 S28 Sugiyama SUMO4 SMT3H4 EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2 T334 Sugiyama TUBA3E ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q6PEY2 T51 Sugiyama TUBA3E QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q6PEY2 T56 Sugiyama TUBA3E MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 T334 Sugiyama TUBA1A TUBA3 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q71U36 T51 Sugiyama TUBA1A TUBA3 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q71U36 T56 Sugiyama TUBA1A TUBA3 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7L014 T885 Sugiyama DDX46 KIAA0801 LGIESQDVMQQATNAILRGGtILAPtVsAKTIAEQLAEKIN
Q7L014 T890 Sugiyama DDX46 KIAA0801 QDVMQQATNAILRGGtILAPtVsAKTIAEQLAEKINAKLNy
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q92522 T55 Sugiyama H1-10 H1FX KRKNSKKKNQPGKySQLVVEtIRRLGERNGSSLAKIYTEAK
Q92882 T200 Sugiyama OSTF1 ATNAACAsLLKKKQGTDAVRtLsNAEDyLDDEDsD______
Q96AY3 T200 Sugiyama FKBP10 FKBP65 PSEC0056 HYNGTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLG
Q96AY3 T203 Sugiyama FKBP10 FKBP65 PSEC0056 GTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGMCP
Q96C86 T318 Sugiyama DCPS DCS1 HINT5 HSPC015 LAEVIENLECDPRHyQQRTLtFALRADDPLLKLLQEAQQS_
Q96G46 T167 Sugiyama DUS3L VGRYLETKPADLGPRCVLFEtFGRCPYGVtCRFAGAHLRPE
Q96G46 T176 Sugiyama DUS3L ADLGPRCVLFEtFGRCPYGVtCRFAGAHLRPEGQNLVQEEL
Q99426 T120 Sugiyama TBCB CG22 CKAP1 DVSRVEKytIsQEAyDQRQDtVRSFLKRsKLGRyNEEERAQ
Q99436 T273 Sugiyama PSMB7 Z AVLTEKITPLEIEVLEEtVQtMDts________________
Q99547 T124 Sugiyama MPHOSPH6 MPP6 TVELDVsDEEMARRyEtLVGtIGKKFARKRDHANYEEDENG
Q99547 Y118 Sugiyama MPHOSPH6 MPP6 EEVEDETVELDVsDEEMARRyEtLVGtIGKKFARKRDHANY
Q99575 S129 Sugiyama POP1 KIAA0061 QARAAEISAMLKAVTQKssNsLVFQtLPRHMRRRAMSHNVK
Q99575 T134 Sugiyama POP1 KIAA0061 EISAMLKAVTQKssNsLVFQtLPRHMRRRAMSHNVKRLPRR
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99700 S508 Sugiyama ATXN2 ATX2 SCA2 TNRC13 TRENKYIPPGQRNREVIsWGsGRQNsPRMGQPGsGSMPSRs
Q99733 T24 Sugiyama NAP1L4 NAP2 HsFsDGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQER
Q99733 T28 Sugiyama NAP1L4 NAP2 DGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQERLDNV
Q99733 T58 Sugiyama NAP1L4 NAP2 LAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQVRCA
Q99733 Y55 Sugiyama NAP1L4 NAP2 PRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQV
Q99832 T57 Sugiyama CCT7 CCTH NIP7-1 RTTLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAK
Q99832 T64 Sugiyama CCT7 CCTH NIP7-1 GMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTLVDIAK
Q99848 S270 Sugiyama EBNA1BP2 EBP2 FGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPGKKGSN
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3 T334 Sugiyama TUBA1C TUBA6 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q9BQE3 T51 Sugiyama TUBA1C TUBA6 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q9BQE3 T56 Sugiyama TUBA1C TUBA6 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BSQ5 S384 SIGNOR|EPSD|PSP CCM2 C7orf22 PP10187 HFENFLETIGVKDGRGIItDsFGRHRRALstTssStTNGNR
Q9BUL8 S39 SIGNOR|EPSD|PSP PDCD10 CCM3 TFAR15 SMPLYAVMYPVFNELERVNLsAAQtLRAAFIKAEKENPGLT
Q9BUL8 T43 SIGNOR|EPSD|PSP PDCD10 CCM3 TFAR15 YAVMYPVFNELERVNLsAAQtLRAAFIKAEKENPGLTQDII
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9H0B6 S539 Sugiyama KLC2 sEsDLEDVGPTAEWNGDGsGsLRRSGsFGKLRDALRRsSEM
Q9H173 T123 Sugiyama SIL1 UNQ545/PRO836 KLQYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAE
Q9H173 T125 Sugiyama SIL1 UNQ545/PRO836 QYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEME
Q9H2U1 T179 Sugiyama DHX36 DDX36 KIAA1488 MLEL1 RHAU NRsyIDRDsEyLLQENEPDGtLDQKLLEDLQKKKNDLRYIE
Q9H788 S124 Sugiyama SH2D4A PPP1R38 SH2A LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NZM1 T172 Sugiyama MYOF FER1L3 KIAA1207 GDEDRLDNAVRGPGPKGPVGtVsEAQLARRLtKVKNSRRML
Q9NZZ3 T23 Sugiyama CHMP5 C9orf83 SNF7DC2 CGI-34 HSPC177 PNAS-114 PNAS-2 RLFGKAKPKAPPPsLtDCIGtVDsRAEsIDKKISRLDAELV
Q9P0J1 T494 Sugiyama PDP1 PDP PPM2C EDQNAATHLIRHAVGNNEFGtVDHERLSKMLSLPEELARMY
Q9P258 T20 Sugiyama RCC2 KIAA1470 TD60 _MPRKKAAAAAWEEPssGNGtARAGPRKRGGPAGRKRERPE
Q9P2E9 T684 Sugiyama RRBP1 KIAA1398 EGEAQRLIEILSEKAGIIQDtWHKATQKGDPVAILKRQLEE
Q9P2J5 T721 Sugiyama LARS1 KIAA1352 LARS PTAVRANGHLLLNSEKMSKstGNFLtLtQAIDKFSADGMRL
Q9P2J5 T726 Sugiyama LARS1 KIAA1352 LARS ANGHLLLNSEKMSKstGNFLtLtQAIDKFSADGMRLALADA
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UBR2 T172 Sugiyama CTSZ ETCNNYQAKDQECDKFNQCGtCNEFKECHAIRNYTLWRVGD
Q9UEG4 T384 Sugiyama ZNF629 KIAA0326 ZNF65 HQRTHLREDPFKCPVCGKTFtLSAtLLRHQRTHTGERPYKC
Q9UEG4 T388 Sugiyama ZNF629 KIAA0326 ZNF65 HLREDPFKCPVCGKTFtLSAtLLRHQRTHTGERPYKCPECG
Q9UII2 S39 Sugiyama ATP5IF1 ATPI ATPIF1 TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF
Q9ULT8 S248 Sugiyama HECTD1 KIAA1131 AKHGLTEELLSRMAAAGGTVsGPssACKPGRSTTGAPSTTA
Q9ULW6 T342 Sugiyama NAP1L2 BPX GTAIEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVT
Q9ULW6 T345 Sugiyama NAP1L2 BPX IEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVTEDF
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UNX3 T93 Sugiyama RPL26L1 RPL26P1 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
Q9UNX3 T94 Sugiyama RPL26L1 RPL26P1 YRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDKD
Q9UQ80 T386 Sugiyama PA2G4 EBP1 tQKKKKKKAsKtAENAtsGEtLEENEAGD____________
Q9Y285 S199 Sugiyama FARSA FARS FARSL FARSLA SAFSTsISKQETELsPEMIssGSWRDRPFKPYNFLAHGVLP
Q9Y2B0 S63 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2B0 T100 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL
Q9Y2B0 T132 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF
Q9Y2W1 Y228 Sugiyama THRAP3 BCLAF2 TRAP150 GGtsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERs
Q9Y3B8 S203 Sugiyama REXO2 SFN SMFN CGI-114 EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK
Q9Y3F4 T48 Sugiyama STRAP MAWD UNRIP YGYFLISACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLN
Q9Y3F4 T54 Sugiyama STRAP MAWD UNRIP SACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLNKDATKA
Q9Y4L1 S742 Sugiyama HYOU1 GRP170 HSPH4 ORP150 KLQDLTLRDLEKQEREKAANsLEAFIFEtQDKLyQPEyQEV
Q9Y4L1 T750 Sugiyama HYOU1 GRP170 HSPH4 ORP150 DLEKQEREKAANsLEAFIFEtQDKLyQPEyQEVsTEEQREE
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Q9Y5L4 T79 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B DNSEQKCIAMCMDRyMDAWNtVsRAYNSRLQRERANM____
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y6E0 T182 Sugiyama STK24 MST3 STK3 VLLSEHGEVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEV
Q9Y6E0 T184 Sugiyama STK24 MST3 STK3 LSEHGEVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEVIK
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Signal Transduction R-HSA-162582 4.125589e-13 12.385 0 0
Axon guidance R-HSA-422475 5.750854e-09 8.240 0 0
Nervous system development R-HSA-9675108 4.751220e-08 7.323 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.951277e-06 5.710 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.354883e-06 5.628 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.156990e-06 5.381 0 0
L1CAM interactions R-HSA-373760 4.230117e-06 5.374 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 5.934966e-06 5.227 0 0
Cellular Senescence R-HSA-2559583 6.310452e-06 5.200 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 6.640810e-06 5.178 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 7.086620e-06 5.150 0 0
Kinesins R-HSA-983189 9.006733e-06 5.045 0 0
MAPK family signaling cascades R-HSA-5683057 9.461267e-06 5.024 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.173837e-05 4.930 0 0
Cell Cycle, Mitotic R-HSA-69278 1.309859e-05 4.883 0 0
Mitotic Prometaphase R-HSA-68877 1.743811e-05 4.759 0 0
Post NMDA receptor activation events R-HSA-438064 1.994057e-05 4.700 0 0
Apoptotic execution phase R-HSA-75153 2.460019e-05 4.609 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 2.830776e-05 4.548 0 0
Recycling pathway of L1 R-HSA-437239 2.899880e-05 4.538 0 0
Mitotic Anaphase R-HSA-68882 3.434612e-05 4.464 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.672893e-05 4.435 0 0
Signaling by Hippo R-HSA-2028269 4.977968e-05 4.303 0 0
Sema4D in semaphorin signaling R-HSA-400685 6.288624e-05 4.201 0 0
M Phase R-HSA-68886 6.177188e-05 4.209 0 0
Semaphorin interactions R-HSA-373755 6.356414e-05 4.197 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 6.684287e-05 4.175 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.927709e-05 4.101 0 0
Diseases of programmed cell death R-HSA-9645723 8.567013e-05 4.067 0 0
Oncogene Induced Senescence R-HSA-2559585 9.092361e-05 4.041 0 0
PKR-mediated signaling R-HSA-9833482 1.210121e-04 3.917 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.191078e-04 3.924 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.206989e-04 3.918 0 0
Separation of Sister Chromatids R-HSA-2467813 1.261222e-04 3.899 0 0
Signaling by ERBB2 R-HSA-1227986 1.843445e-04 3.734 0 0
Cell Cycle R-HSA-1640170 1.848651e-04 3.733 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.069506e-04 3.684 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 3.032373e-04 3.518 0 0
MHC class II antigen presentation R-HSA-2132295 3.015173e-04 3.521 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.277390e-04 3.484 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 3.870465e-04 3.412 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 4.308840e-04 3.366 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 4.309600e-04 3.366 0 0
Transport of connexons to the plasma membrane R-HSA-190872 4.879404e-04 3.312 0 0
Cell junction organization R-HSA-446728 4.917124e-04 3.308 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 6.824448e-04 3.166 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 7.502797e-04 3.125 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 7.502797e-04 3.125 0 0
ESR-mediated signaling R-HSA-8939211 7.279397e-04 3.138 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 7.807055e-04 3.108 0 0
Amplification of signal from the kinetochores R-HSA-141424 7.807055e-04 3.108 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 8.067267e-04 3.093 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 9.482289e-04 3.023 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 9.153929e-04 3.038 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 9.482289e-04 3.023 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 9.808534e-04 3.008 0 0
Aggrephagy R-HSA-9646399 9.837442e-04 3.007 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.016854e-03 2.993 0 0
Signaling by PTK6 R-HSA-8848021 1.016854e-03 2.993 0 0
Neuronal System R-HSA-112316 1.036211e-03 2.985 0 0
Cellular responses to stress R-HSA-2262752 1.011929e-03 2.995 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.088661e-03 2.963 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.110198e-03 2.955 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.304300e-03 2.885 0 0
Cell-Cell communication R-HSA-1500931 1.281446e-03 2.892 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.277555e-03 2.894 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.378792e-03 2.861 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.390500e-03 2.857 0 0
EPH-Ephrin signaling R-HSA-2682334 1.545179e-03 2.811 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.497967e-03 2.824 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.623296e-03 2.790 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.671680e-03 2.777 0 0
Programmed Cell Death R-HSA-5357801 1.695604e-03 2.771 0 0
Gap junction trafficking R-HSA-190828 1.844902e-03 2.734 0 0
Cellular responses to stimuli R-HSA-8953897 1.855956e-03 2.731 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.881461e-03 2.726 0 0
RAF activation R-HSA-5673000 1.973204e-03 2.705 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 2.124601e-03 2.673 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 2.382706e-03 2.623 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 2.632588e-03 2.580 0 0
Signaling by VEGF R-HSA-194138 2.896478e-03 2.538 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.053120e-03 2.515 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 3.061313e-03 2.514 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 3.002760e-03 2.522 0 0
Selective autophagy R-HSA-9663891 3.137822e-03 2.503 0 0
Platelet sensitization by LDL R-HSA-432142 3.128503e-03 2.505 0 0
Gap junction trafficking and regulation R-HSA-157858 3.213848e-03 2.493 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 3.386367e-03 2.470 0 0
Signaling by GSK3beta mutants R-HSA-5339716 3.955832e-03 2.403 0 0
Cell Cycle Checkpoints R-HSA-69620 4.114392e-03 2.386 0 0
Sensory processing of sound R-HSA-9659379 4.320968e-03 2.364 0 0
Interleukin-37 signaling R-HSA-9008059 4.560826e-03 2.341 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.901296e-03 2.310 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.901296e-03 2.310 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 4.956478e-03 2.305 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 4.956478e-03 2.305 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 4.956478e-03 2.305 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 4.956478e-03 2.305 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 4.956478e-03 2.305 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.643916e-03 2.333 0 0
Signaling by LTK R-HSA-9842663 4.956478e-03 2.305 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.901296e-03 2.310 0 0
Apoptosis R-HSA-109581 4.689956e-03 2.329 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 5.185198e-03 2.285 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 5.192744e-03 2.285 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.485005e-03 2.261 0 0
NRAGE signals death through JNK R-HSA-193648 6.320983e-03 2.199 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 6.125275e-03 2.213 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 6.320983e-03 2.199 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 6.645574e-03 2.177 0 0
Membrane Trafficking R-HSA-199991 7.187282e-03 2.143 0 0
Hedgehog 'off' state R-HSA-5610787 8.272864e-03 2.082 0 0
Gap junction assembly R-HSA-190861 8.372649e-03 2.077 0 0
Developmental Biology R-HSA-1266738 8.512790e-03 2.070 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 8.915268e-03 2.050 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 8.939246e-03 2.049 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 8.939246e-03 2.049 0 0
Cell-extracellular matrix interactions R-HSA-446353 8.939246e-03 2.049 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.001845e-03 2.046 0 0
Adaptive Immune System R-HSA-1280218 9.783572e-03 2.010 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.260055e-02 1.900 0 0
Regulation of TP53 Expression R-HSA-6804754 1.260055e-02 1.900 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.260055e-02 1.900 0 0
Diseases of Cellular Senescence R-HSA-9630747 1.260055e-02 1.900 0 0
Diseases of cellular response to stress R-HSA-9675132 1.260055e-02 1.900 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.260055e-02 1.900 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.260055e-02 1.900 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.260055e-02 1.900 0 0
Type I hemidesmosome assembly R-HSA-446107 1.161982e-02 1.935 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.161982e-02 1.935 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.161982e-02 1.935 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.250271e-02 1.903 0 0
Voltage gated Potassium channels R-HSA-1296072 1.153470e-02 1.938 0 0
HDMs demethylate histones R-HSA-3214842 1.062317e-02 1.974 0 0
Long-term potentiation R-HSA-9620244 1.062317e-02 1.974 0 0
TRP channels R-HSA-3295583 1.203976e-02 1.919 0 0
Transmission across Chemical Synapses R-HSA-112315 1.181833e-02 1.927 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.161982e-02 1.935 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.198340e-02 1.921 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.314997e-02 1.881 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.458048e-02 1.836 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.415153e-02 1.849 0 0
DNA Double Strand Break Response R-HSA-5693606 1.520753e-02 1.818 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.404226e-02 1.853 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.406039e-02 1.852 0 0
Signaling by ALK R-HSA-201556 1.406039e-02 1.852 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.545752e-02 1.811 0 0
Signaling by Hedgehog R-HSA-5358351 1.567610e-02 1.805 0 0
Death Receptor Signaling R-HSA-73887 1.572373e-02 1.803 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.575394e-02 1.803 0 0
Potassium Channels R-HSA-1296071 1.656073e-02 1.781 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 1.686435e-02 1.773 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.686435e-02 1.773 0 0
Ephrin signaling R-HSA-3928664 1.686435e-02 1.773 0 0
Immune System R-HSA-168256 1.693512e-02 1.771 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.694796e-02 1.771 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.704447e-02 1.768 0 0
Regulation of CDH11 function R-HSA-9762292 1.804354e-02 1.744 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.832474e-02 1.737 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.840864e-02 1.735 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.853441e-02 1.732 0 0
Axonal growth stimulation R-HSA-209563 1.915495e-02 1.718 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 2.186031e-02 1.660 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 2.186031e-02 1.660 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 2.186031e-02 1.660 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 2.159091e-02 1.666 0 0
Interleukin-2 signaling R-HSA-9020558 2.186031e-02 1.660 0 0
Signaling by APC mutants R-HSA-4839744 2.186031e-02 1.660 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 2.000643e-02 1.699 0 0
Chaperonin-mediated protein folding R-HSA-390466 2.190892e-02 1.659 0 0
Defective pyroptosis R-HSA-9710421 2.200564e-02 1.657 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.277151e-02 1.643 0 0
Cell-cell junction organization R-HSA-421270 2.282030e-02 1.642 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 2.297617e-02 1.639 0 0
Hemostasis R-HSA-109582 2.318491e-02 1.635 0 0
G0 and Early G1 R-HSA-1538133 2.326492e-02 1.633 0 0
Netrin-1 signaling R-HSA-373752 2.389523e-02 1.622 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.683850e-02 1.571 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 2.683850e-02 1.571 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 2.683850e-02 1.571 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 2.608299e-02 1.584 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.799349e-02 1.553 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.799349e-02 1.553 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.799349e-02 1.553 0 0
Integrin signaling R-HSA-354192 2.562461e-02 1.591 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.465509e-02 1.608 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.799349e-02 1.553 0 0
Signaling by RAS mutants R-HSA-6802949 2.799349e-02 1.553 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 2.813220e-02 1.551 0 0
Mitotic Prophase R-HSA-68875 2.843758e-02 1.546 0 0
Signaling by AXIN mutants R-HSA-4839735 2.608299e-02 1.584 0 0
Signaling by AMER1 mutants R-HSA-4839748 2.608299e-02 1.584 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.816134e-02 1.550 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 2.500469e-02 1.602 0 0
Interleukin-12 signaling R-HSA-9020591 2.740750e-02 1.562 0 0
G2/M Transition R-HSA-69275 2.917123e-02 1.535 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 3.020618e-02 1.520 0 0
Protein folding R-HSA-391251 3.053704e-02 1.515 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 3.071042e-02 1.513 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 3.071042e-02 1.513 0 0
G alpha (12/13) signalling events R-HSA-416482 3.083869e-02 1.511 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.113340e-02 1.507 0 0
Signaling by ALK in cancer R-HSA-9700206 3.113340e-02 1.507 0 0
Cytokine Signaling in Immune system R-HSA-1280215 3.122013e-02 1.506 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.134085e-02 1.504 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 3.253035e-02 1.488 0 0
Intraflagellar transport R-HSA-5620924 3.253035e-02 1.488 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 3.255180e-02 1.487 0 0
Drug resistance of KIT mutants R-HSA-9669937 4.111206e-02 1.386 0 0
KIT mutants bind TKIs R-HSA-9669921 4.111206e-02 1.386 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 4.111206e-02 1.386 0 0
Imatinib-resistant KIT mutants R-HSA-9669917 4.111206e-02 1.386 0 0
Dasatinib-resistant KIT mutants R-HSA-9669914 4.111206e-02 1.386 0 0
Nilotinib-resistant KIT mutants R-HSA-9669926 4.111206e-02 1.386 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 4.111206e-02 1.386 0 0
Masitinib-resistant KIT mutants R-HSA-9669924 4.111206e-02 1.386 0 0
Regorafenib-resistant KIT mutants R-HSA-9669929 4.111206e-02 1.386 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 4.111206e-02 1.386 0 0
Sunitinib-resistant KIT mutants R-HSA-9669934 4.111206e-02 1.386 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 4.111206e-02 1.386 0 0
Sorafenib-resistant KIT mutants R-HSA-9669936 4.111206e-02 1.386 0 0
Formation of axial mesoderm R-HSA-9796292 3.573927e-02 1.447 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.515618e-02 1.454 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.968591e-02 1.401 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 3.650906e-02 1.438 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 3.768704e-02 1.424 0 0
Meiotic recombination R-HSA-912446 4.018757e-02 1.396 0 0
COPI-mediated anterograde transport R-HSA-6807878 3.934286e-02 1.405 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.899746e-02 1.409 0 0
Neurodegenerative Diseases R-HSA-8863678 3.899746e-02 1.409 0 0
Regulation of TP53 Degradation R-HSA-6804757 3.656529e-02 1.437 0 0
Muscle contraction R-HSA-397014 3.911764e-02 1.408 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.508840e-02 1.455 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.508840e-02 1.455 0 0
NrCAM interactions R-HSA-447038 3.554754e-02 1.449 0 0
Signaling by Interleukins R-HSA-449147 3.769701e-02 1.424 0 0
Regulation of KIT signaling R-HSA-1433559 4.116432e-02 1.385 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 4.120973e-02 1.385 0 0
Regulated Necrosis R-HSA-5218859 4.364141e-02 1.360 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.364141e-02 1.360 0 0
Meiosis R-HSA-1500620 4.513364e-02 1.345 0 0
GLI proteins bind promoters of Hh responsive genes to promote transcription R-HSA-5635851 4.518502e-02 1.345 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.518502e-02 1.345 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.518502e-02 1.345 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.538003e-02 1.343 0 0
FOXO-mediated transcription R-HSA-9614085 4.538003e-02 1.343 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 4.697861e-02 1.328 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 4.697861e-02 1.328 0 0
Adherens junctions interactions R-HSA-418990 4.715151e-02 1.327 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 4.886274e-02 1.311 0 0
Cardiac conduction R-HSA-5576891 4.928508e-02 1.307 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 5.190123e-02 1.285 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 5.190123e-02 1.285 0 0
Interaction between L1 and Ankyrins R-HSA-445095 5.190123e-02 1.285 0 0
Interleukin-12 family signaling R-HSA-447115 5.240322e-02 1.281 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.317371e-02 1.274 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 5.374777e-02 1.270 0 0
PKMTs methylate histone lysines R-HSA-3214841 5.374777e-02 1.270 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 5.374777e-02 1.270 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 5.446459e-02 1.264 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.566013e-02 1.254 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 6.688791e-02 1.175 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 6.666625e-02 1.176 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 6.666625e-02 1.176 0 0
DNA methylation R-HSA-5334118 6.164494e-02 1.210 0 0
Signaling by ERBB4 R-HSA-1236394 6.045156e-02 1.219 0 0
MAP2K and MAPK activation R-HSA-5674135 5.766068e-02 1.239 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 6.291318e-02 1.201 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 5.973988e-02 1.224 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.688791e-02 1.175 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 6.688791e-02 1.175 0 0
Signaling by NOTCH1 R-HSA-1980143 6.682671e-02 1.175 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 6.164494e-02 1.210 0 0
G2/M DNA damage checkpoint R-HSA-69473 6.045156e-02 1.219 0 0
Vesicle-mediated transport R-HSA-5653656 6.878063e-02 1.163 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.566013e-02 1.254 0 0
Autophagy R-HSA-9612973 6.725217e-02 1.172 0 0
MECP2 regulates transcription factors R-HSA-9022707 6.688791e-02 1.175 0 0
Signaling by Nuclear Receptors R-HSA-9006931 5.844014e-02 1.233 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.688791e-02 1.175 0 0
Regulation of PTEN gene transcription R-HSA-8943724 6.956343e-02 1.158 0 0
RAB geranylgeranylation R-HSA-8873719 6.956343e-02 1.158 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 7.228289e-02 1.141 0 0
Macroautophagy R-HSA-1632852 7.352003e-02 1.134 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 7.394100e-02 1.131 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 7.484718e-02 1.126 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 7.484718e-02 1.126 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 7.484718e-02 1.126 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 7.489662e-02 1.126 0 0
Signaling by WNT in cancer R-HSA-4791275 7.792963e-02 1.108 0 0
FGFR1b ligand binding and activation R-HSA-190370 7.878899e-02 1.104 0 0
Activation of RAS in B cells R-HSA-1169092 7.878899e-02 1.104 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 7.878899e-02 1.104 0 0
Adrenoceptors R-HSA-390696 7.878899e-02 1.104 0 0
Hereditary fructose intolerance R-HSA-5657560 8.053631e-02 1.094 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 8.053631e-02 1.094 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 8.053631e-02 1.094 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 8.053631e-02 1.094 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 8.053631e-02 1.094 0 0
Inhibition of PKR R-HSA-169131 8.053631e-02 1.094 0 0
STING mediated induction of host immune responses R-HSA-1834941 8.155147e-02 1.089 0 0
Regulation of necroptotic cell death R-HSA-5675482 8.378991e-02 1.077 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 8.378991e-02 1.077 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 8.378991e-02 1.077 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 8.378991e-02 1.077 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 8.522968e-02 1.069 0 0
IGF1R signaling cascade R-HSA-2428924 8.575405e-02 1.067 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 1.183420e-01 0.927 0 0
Signaling by extracellular domain mutants of KIT R-HSA-9680187 1.183420e-01 0.927 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 1.183420e-01 0.927 0 0
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935 1.183420e-01 0.927 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 1.183420e-01 0.927 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 1.183420e-01 0.927 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 1.183420e-01 0.927 0 0
Signaling by kinase domain mutants of KIT R-HSA-9669933 1.183420e-01 0.927 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 1.183420e-01 0.927 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 1.183420e-01 0.927 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 1.183420e-01 0.927 0 0
MPS IIID - Sanfilippo syndrome D R-HSA-2206305 1.183420e-01 0.927 0 0
Gap junction degradation R-HSA-190873 9.128919e-02 1.040 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.043193e-01 0.982 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.043193e-01 0.982 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.178148e-01 0.929 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.178148e-01 0.929 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.178148e-01 0.929 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 8.948435e-02 1.048 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 9.772573e-02 1.010 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 9.772573e-02 1.010 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 9.772573e-02 1.010 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 1.062613e-01 0.974 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.092762e-01 0.961 0 0
p75NTR regulates axonogenesis R-HSA-193697 9.128919e-02 1.040 0 0
Signal attenuation R-HSA-74749 1.043193e-01 0.982 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 1.161335e-01 0.935 0 0
Co-inhibition by CTLA4 R-HSA-389513 8.948435e-02 1.048 0 0
Adipogenesis R-HSA-9843745 9.523039e-02 1.021 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 9.613376e-02 1.017 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 1.092762e-01 0.961 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.161335e-01 0.935 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.009981e-02 1.045 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.183420e-01 0.927 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.183420e-01 0.927 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 9.128919e-02 1.040 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 1.043193e-01 0.982 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.178148e-01 0.929 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.109720e-01 0.955 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.152468e-01 0.938 0 0
Formation of definitive endoderm R-HSA-9823730 8.948435e-02 1.048 0 0
Cilium Assembly R-HSA-5617833 1.069726e-01 0.971 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.135689e-01 0.945 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.183420e-01 0.927 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 9.128919e-02 1.040 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 1.062613e-01 0.974 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.043193e-01 0.982 0 0
ER to Golgi Anterograde Transport R-HSA-199977 9.230843e-02 1.035 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.043193e-01 0.982 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.062613e-01 0.974 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.161335e-01 0.935 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 9.128919e-02 1.040 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 9.128919e-02 1.040 0 0
Mitochondrial calcium ion transport R-HSA-8949215 1.062613e-01 0.974 0 0
G1/S-Specific Transcription R-HSA-69205 1.092762e-01 0.961 0 0
Signaling by Leptin R-HSA-2586552 1.043193e-01 0.982 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.083081e-01 0.965 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.186015e-01 0.926 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.186015e-01 0.926 0 0
Hedgehog 'on' state R-HSA-5632684 1.186015e-01 0.926 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.188789e-01 0.925 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.231737e-01 0.909 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.235387e-01 0.908 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.237434e-01 0.907 0 0
Interleukin receptor SHC signaling R-HSA-912526 1.241559e-01 0.906 0 0
Growth hormone receptor signaling R-HSA-982772 1.241559e-01 0.906 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.253121e-01 0.902 0 0
HDACs deacetylate histones R-HSA-3214815 1.285920e-01 0.891 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 1.303910e-01 0.885 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.317155e-01 0.880 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.317155e-01 0.880 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 1.317155e-01 0.880 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.317155e-01 0.880 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.317155e-01 0.880 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.317155e-01 0.880 0 0
Classical Kir channels R-HSA-1296053 1.893601e-01 0.723 0 0
HCN channels R-HSA-1296061 2.226973e-01 0.652 0 0
NADE modulates death signalling R-HSA-205025 2.226973e-01 0.652 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 2.226973e-01 0.652 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.226973e-01 0.652 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.226973e-01 0.652 0 0
Nucleotide catabolism defects R-HSA-9735786 2.226973e-01 0.652 0 0
ATP sensitive Potassium channels R-HSA-1296025 2.226973e-01 0.652 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.226973e-01 0.652 0 0
IRS activation R-HSA-74713 2.546655e-01 0.594 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.546655e-01 0.594 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 2.546655e-01 0.594 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 2.546655e-01 0.594 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 2.853208e-01 0.545 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.853208e-01 0.545 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.853208e-01 0.545 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 2.853208e-01 0.545 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.605126e-01 0.794 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.147170e-01 0.502 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 3.147170e-01 0.502 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 3.147170e-01 0.502 0 0
Defective CHST3 causes SEDCJD R-HSA-3595172 3.147170e-01 0.502 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.903079e-01 0.721 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 1.334850e-01 0.875 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.054696e-01 0.687 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 3.429058e-01 0.465 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 3.429058e-01 0.465 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 3.429058e-01 0.465 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.429058e-01 0.465 0 0
SOS-mediated signalling R-HSA-112412 3.429058e-01 0.465 0 0
Recycling of eIF2:GDP R-HSA-72731 3.429058e-01 0.465 0 0
Defective CHSY1 causes TPBS R-HSA-3595177 3.429058e-01 0.465 0 0
FGFR3b ligand binding and activation R-HSA-190371 3.429058e-01 0.465 0 0
Signaling by EGFR in Cancer R-HSA-1643713 1.528308e-01 0.816 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.628172e-01 0.788 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 1.628172e-01 0.788 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.361277e-01 0.627 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.699368e-01 0.432 0 0
phospho-PLA2 pathway R-HSA-111995 3.699368e-01 0.432 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.699368e-01 0.432 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 3.699368e-01 0.432 0 0
Formation of annular gap junctions R-HSA-196025 3.699368e-01 0.432 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.377788e-01 0.861 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.958573e-01 0.402 0 0
Regulated proteolysis of p75NTR R-HSA-193692 3.958573e-01 0.402 0 0
CASP8 activity is inhibited R-HSA-5218900 3.958573e-01 0.402 0 0
ALK mutants bind TKIs R-HSA-9700645 3.958573e-01 0.402 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.530405e-01 0.815 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 2.824557e-01 0.549 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 2.978746e-01 0.526 0 0
Striated Muscle Contraction R-HSA-390522 2.371887e-01 0.625 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.132403e-01 0.504 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.132403e-01 0.504 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 3.132403e-01 0.504 0 0
Notch-HLH transcription pathway R-HSA-350054 3.285312e-01 0.483 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.285312e-01 0.483 0 0
Nuclear Receptor transcription pathway R-HSA-383280 1.567815e-01 0.805 0 0
mRNA 3'-end processing R-HSA-72187 2.462537e-01 0.609 0 0
Meiotic synapsis R-HSA-1221632 2.553080e-01 0.593 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.556035e-01 0.592 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 3.387732e-01 0.470 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.461175e-01 0.609 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.530122e-01 0.597 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 2.427987e-01 0.615 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 2.810895e-01 0.551 0 0
Formation of a pool of free 40S subunits R-HSA-72689 2.882183e-01 0.540 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 3.484034e-01 0.458 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 3.484034e-01 0.458 0 0
HCMV Early Events R-HSA-9609690 1.981878e-01 0.703 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 3.277962e-01 0.484 0 0
Post-translational protein phosphorylation R-HSA-8957275 3.098196e-01 0.509 0 0
AURKA Activation by TPX2 R-HSA-8854518 3.766688e-01 0.424 0 0
Viral mRNA Translation R-HSA-192823 3.463601e-01 0.460 0 0
Neutrophil degranulation R-HSA-6798695 1.571343e-01 0.804 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 3.832620e-01 0.417 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.847357e-01 0.733 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 2.594499e-01 0.586 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 1.833415e-01 0.737 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 1.938497e-01 0.713 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 2.594499e-01 0.586 0 0
Co-inhibition by PD-1 R-HSA-389948 2.149105e-01 0.668 0 0
mRNA Splicing R-HSA-72172 2.366147e-01 0.626 0 0
Signaling by SCF-KIT R-HSA-1433557 3.614784e-01 0.442 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.688262e-01 0.433 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.900546e-01 0.721 0 0
Signaling by EGFR R-HSA-177929 2.828410e-01 0.548 0 0
Ribosome-associated quality control R-HSA-9948299 3.278950e-01 0.484 0 0
Processing of DNA double-strand break ends R-HSA-5693607 3.196369e-01 0.495 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 2.207547e-01 0.656 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.764407e-01 0.753 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 1.619330e-01 0.791 0 0
Signaling by FGFR R-HSA-190236 3.098196e-01 0.509 0 0
Peptide chain elongation R-HSA-156902 2.257804e-01 0.646 0 0
Myogenesis R-HSA-525793 1.528308e-01 0.816 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.285312e-01 0.483 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.870227e-01 0.728 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.741436e-01 0.759 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 2.195581e-01 0.658 0 0
Cap-dependent Translation Initiation R-HSA-72737 3.069334e-01 0.513 0 0
Developmental Cell Lineages R-HSA-9734767 3.048459e-01 0.516 0 0
Eukaryotic Translation Initiation R-HSA-72613 3.069334e-01 0.513 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.459655e-01 0.836 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 2.207547e-01 0.656 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 3.160182e-01 0.500 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.652069e-01 0.437 0 0
Signaling by FGFR2 R-HSA-5654738 3.115023e-01 0.507 0 0
Regulation of TP53 Activity R-HSA-5633007 1.342071e-01 0.872 0 0
Signaling by FGFR3 R-HSA-5654741 1.853173e-01 0.732 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 3.610971e-01 0.442 0 0
Activation of HOX genes during differentiation R-HSA-5619507 3.610971e-01 0.442 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.553080e-01 0.593 0 0
Signaling by FGFR4 R-HSA-5654743 1.689051e-01 0.772 0 0
Signalling to RAS R-HSA-167044 2.978746e-01 0.526 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.226973e-01 0.652 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 2.546655e-01 0.594 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.546655e-01 0.594 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.459655e-01 0.836 0 0
FGFR1c ligand binding and activation R-HSA-190373 1.605126e-01 0.794 0 0
Tight junction interactions R-HSA-420029 1.430484e-01 0.845 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.609008e-01 0.793 0 0
Signaling by FGFR1 R-HSA-5654736 1.347327e-01 0.871 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.605424e-01 0.794 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.605424e-01 0.794 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.605424e-01 0.794 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.605424e-01 0.794 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.685755e-01 0.773 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.427987e-01 0.615 0 0
Chromatin modifying enzymes R-HSA-3247509 3.802340e-01 0.420 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 2.207547e-01 0.656 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.515554e-01 0.599 0 0
Parasite infection R-HSA-9664407 2.184893e-01 0.661 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 2.184893e-01 0.661 0 0
Leishmania phagocytosis R-HSA-9664417 2.184893e-01 0.661 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 1.605126e-01 0.794 0 0
TNF signaling R-HSA-75893 1.347327e-01 0.871 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 2.921197e-01 0.534 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.937111e-01 0.713 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 2.226973e-01 0.652 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 2.226973e-01 0.652 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 2.226973e-01 0.652 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.853208e-01 0.545 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 2.400956e-01 0.620 0 0
Regulation of mitotic cell cycle R-HSA-453276 2.400956e-01 0.620 0 0
Eukaryotic Translation Termination R-HSA-72764 2.882183e-01 0.540 0 0
FGFR1 ligand binding and activation R-HSA-190242 2.515554e-01 0.599 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 3.273971e-01 0.485 0 0
Mitophagy R-HSA-5205647 2.482810e-01 0.605 0 0
Regulation of CDH1 Function R-HSA-9764561 2.921197e-01 0.534 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.958573e-01 0.402 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 3.132403e-01 0.504 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 2.911861e-01 0.536 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.515554e-01 0.599 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.410017e-01 0.851 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.666259e-01 0.778 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 1.833415e-01 0.737 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 3.223131e-01 0.492 0 0
Ceramide signalling R-HSA-193681 2.853208e-01 0.545 0 0
Phosphorylation of Emi1 R-HSA-176417 2.853208e-01 0.545 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.605126e-01 0.794 0 0
Intracellular metabolism of fatty acids regulates insulin secretion R-HSA-434313 3.147170e-01 0.502 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.334850e-01 0.875 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 2.054696e-01 0.687 0 0
Regulation by c-FLIP R-HSA-3371378 3.699368e-01 0.432 0 0
Signalling to ERKs R-HSA-187687 2.594499e-01 0.586 0 0
RNA Polymerase I Transcription R-HSA-73864 1.567815e-01 0.805 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.515132e-01 0.820 0 0
Deadenylation of mRNA R-HSA-429947 3.588112e-01 0.445 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.046466e-01 0.516 0 0
G2/M Checkpoints R-HSA-69481 1.478526e-01 0.830 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 3.885765e-01 0.411 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.201677e-01 0.495 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.566831e-01 0.805 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.605424e-01 0.794 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 3.588112e-01 0.445 0 0
Interferon Signaling R-HSA-913531 1.890855e-01 0.723 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.552679e-01 0.593 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 3.429058e-01 0.465 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.599598e-01 0.585 0 0
Formation of the cornified envelope R-HSA-6809371 3.603777e-01 0.443 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.546655e-01 0.594 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 3.699368e-01 0.432 0 0
HSF1 activation R-HSA-3371511 2.706829e-01 0.568 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 3.160182e-01 0.500 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 3.160182e-01 0.500 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.737658e-01 0.427 0 0
G-protein mediated events R-HSA-112040 3.860716e-01 0.413 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.652781e-01 0.782 0 0
Interleukin-2 family signaling R-HSA-451927 1.377788e-01 0.861 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.226973e-01 0.652 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.429058e-01 0.465 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.429058e-01 0.465 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.958573e-01 0.402 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 3.958573e-01 0.402 0 0
GPER1 signaling R-HSA-9634597 2.108387e-01 0.676 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 1.932190e-01 0.714 0 0
Attenuation phase R-HSA-3371568 3.160182e-01 0.500 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 2.478181e-01 0.606 0 0
TCF dependent signaling in response to WNT R-HSA-201681 2.333646e-01 0.632 0 0
Protein-protein interactions at synapses R-HSA-6794362 3.523832e-01 0.453 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.132403e-01 0.504 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 3.268248e-01 0.486 0 0
Cellular response to chemical stress R-HSA-9711123 3.271385e-01 0.485 0 0
Regulation of BACH1 activity R-HSA-9708530 2.054696e-01 0.687 0 0
Pyroptosis R-HSA-5620971 1.729924e-01 0.762 0 0
HSF1-dependent transactivation R-HSA-3371571 2.372727e-01 0.625 0 0
Acyl chain remodelling of PS R-HSA-1482801 3.737658e-01 0.427 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 3.469096e-01 0.460 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.455865e-01 0.837 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 3.268248e-01 0.486 0 0
Platelet degranulation R-HSA-114608 1.478526e-01 0.830 0 0
rRNA processing R-HSA-72312 3.702030e-01 0.432 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.455865e-01 0.837 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 3.469096e-01 0.460 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.685755e-01 0.773 0 0
G1 Phase R-HSA-69236 3.727895e-01 0.429 0 0
Cyclin D associated events in G1 R-HSA-69231 3.727895e-01 0.429 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.609008e-01 0.793 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.726654e-01 0.763 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.893601e-01 0.723 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 2.226973e-01 0.652 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.226973e-01 0.652 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.853208e-01 0.545 0 0
Abacavir transmembrane transport R-HSA-2161517 3.147170e-01 0.502 0 0
Activation of SMO R-HSA-5635838 2.054696e-01 0.687 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.429058e-01 0.465 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.429058e-01 0.465 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.429058e-01 0.465 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 3.699368e-01 0.432 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.699368e-01 0.432 0 0
Dimerization of procaspase-8 R-HSA-69416 3.699368e-01 0.432 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 3.699368e-01 0.432 0 0
ARMS-mediated activation R-HSA-170984 3.958573e-01 0.402 0 0
Effects of PIP2 hydrolysis R-HSA-114508 2.371887e-01 0.625 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.482810e-01 0.605 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 2.553080e-01 0.593 0 0
G1/S Transition R-HSA-69206 2.386264e-01 0.622 0 0
Toll-like Receptor Cascades R-HSA-168898 2.714948e-01 0.566 0 0
Innate Immune System R-HSA-168249 3.414252e-01 0.467 0 0
Amine ligand-binding receptors R-HSA-375280 3.727895e-01 0.429 0 0
Glycolysis R-HSA-70171 1.893199e-01 0.723 0 0
Intra-Golgi traffic R-HSA-6811438 1.530405e-01 0.815 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.453661e-01 0.838 0 0
Degradation of CDH1 R-HSA-9766229 2.195581e-01 0.658 0 0
Ca-dependent events R-HSA-111996 1.609008e-01 0.793 0 0
Ion homeostasis R-HSA-5578775 1.347327e-01 0.871 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 3.885765e-01 0.411 0 0
Histamine receptors R-HSA-390650 1.893601e-01 0.723 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.147170e-01 0.502 0 0
Rap1 signalling R-HSA-392517 2.670074e-01 0.573 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.958573e-01 0.402 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.792691e-01 0.746 0 0
Selenocysteine synthesis R-HSA-2408557 3.316807e-01 0.479 0 0
Signaling by ROBO receptors R-HSA-376176 2.278311e-01 0.642 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 2.054696e-01 0.687 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 1.528308e-01 0.816 0 0
Amyloid fiber formation R-HSA-977225 1.746083e-01 0.758 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.046466e-01 0.516 0 0
Reproduction R-HSA-1474165 2.734101e-01 0.563 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.770462e-01 0.752 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.906255e-01 0.720 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.588803e-01 0.799 0 0
Signaling by TGFBR3 R-HSA-9839373 3.952862e-01 0.403 0 0
Deubiquitination R-HSA-5688426 1.866488e-01 0.729 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.941971e-01 0.404 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.226973e-01 0.652 0 0
Co-inhibition by BTLA R-HSA-9927353 2.546655e-01 0.594 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.546655e-01 0.594 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.459655e-01 0.836 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.853208e-01 0.545 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.147170e-01 0.502 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 2.054696e-01 0.687 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.429058e-01 0.465 0 0
WNT mediated activation of DVL R-HSA-201688 3.958573e-01 0.402 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 3.958573e-01 0.402 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 3.958573e-01 0.402 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.958573e-01 0.402 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.958573e-01 0.402 0 0
Trafficking of AMPA receptors R-HSA-399719 2.045027e-01 0.689 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.132403e-01 0.504 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.437275e-01 0.464 0 0
PLC beta mediated events R-HSA-112043 3.295668e-01 0.482 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 3.295668e-01 0.482 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.461175e-01 0.609 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 1.528308e-01 0.816 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 2.482810e-01 0.605 0 0
Signaling by NOTCH R-HSA-157118 3.010451e-01 0.521 0 0
SARS-CoV-1-host interactions R-HSA-9692914 3.758694e-01 0.425 0 0
Glucose metabolism R-HSA-70326 3.135387e-01 0.504 0 0
Protein methylation R-HSA-8876725 1.903079e-01 0.721 0 0
GP1b-IX-V activation signalling R-HSA-430116 3.958573e-01 0.402 0 0
Ion channel transport R-HSA-983712 3.770698e-01 0.424 0 0
Signaling by NTRKs R-HSA-166520 2.661328e-01 0.575 0 0
Stimuli-sensing channels R-HSA-2672351 2.427987e-01 0.615 0 0
Calmodulin induced events R-HSA-111933 2.706829e-01 0.568 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 3.578294e-01 0.446 0 0
Response of endothelial cells to shear stress R-HSA-9860931 3.537228e-01 0.451 0 0
DAG and IP3 signaling R-HSA-1489509 3.840615e-01 0.416 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 3.589536e-01 0.445 0 0
Formation of the nephric duct R-HSA-9830364 1.430484e-01 0.845 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 2.515554e-01 0.599 0 0
CaM pathway R-HSA-111997 2.706829e-01 0.568 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.316807e-01 0.479 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 2.853208e-01 0.545 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 2.853208e-01 0.545 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 3.147170e-01 0.502 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 3.429058e-01 0.465 0 0
Synthesis of PG R-HSA-1483148 2.207547e-01 0.656 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 3.699368e-01 0.432 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.958573e-01 0.402 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 3.285312e-01 0.483 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 2.462537e-01 0.609 0 0
Complex III assembly R-HSA-9865881 3.588112e-01 0.445 0 0
Influenza Infection R-HSA-168255 2.151248e-01 0.667 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 3.267691e-01 0.486 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.903079e-01 0.721 0 0
Signal transduction by L1 R-HSA-445144 2.824557e-01 0.549 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 2.583027e-01 0.588 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 2.853208e-01 0.545 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.958573e-01 0.402 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.605424e-01 0.794 0 0
FLT3 Signaling R-HSA-9607240 3.273971e-01 0.485 0 0
Platelet homeostasis R-HSA-418346 3.758694e-01 0.425 0 0
PTEN Regulation R-HSA-6807070 3.340732e-01 0.476 0 0
Co-stimulation by CD28 R-HSA-389356 2.108387e-01 0.676 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.605126e-01 0.794 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 1.347327e-01 0.871 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 3.958573e-01 0.402 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.277962e-01 0.484 0 0
Polo-like kinase mediated events R-HSA-156711 2.515554e-01 0.599 0 0
Syndecan interactions R-HSA-3000170 3.437275e-01 0.464 0 0
Synaptic adhesion-like molecules R-HSA-8849932 2.515554e-01 0.599 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 3.958573e-01 0.402 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 2.033997e-01 0.692 0 0
Interleukin-7 signaling R-HSA-1266695 1.430484e-01 0.845 0 0
PI Metabolism R-HSA-1483255 3.390118e-01 0.470 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 2.261860e-01 0.646 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.437275e-01 0.464 0 0
Interleukin-1 family signaling R-HSA-446652 1.825736e-01 0.739 0 0
Apoptotic factor-mediated response R-HSA-111471 2.515554e-01 0.599 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.820802e-01 0.740 0 0
Gene Silencing by RNA R-HSA-211000 2.366262e-01 0.626 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 2.482810e-01 0.605 0 0
XBP1(S) activates chaperone genes R-HSA-381038 2.125412e-01 0.673 0 0
IRE1alpha activates chaperones R-HSA-381070 2.530122e-01 0.597 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 3.046466e-01 0.516 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 3.389807e-01 0.470 0 0
DNA Replication Pre-Initiation R-HSA-69002 3.980468e-01 0.400 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.017024e-01 0.396 0 0
Packaging Of Telomere Ends R-HSA-171306 4.032298e-01 0.394 0 0
Cristae formation R-HSA-8949613 4.032298e-01 0.394 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 4.032298e-01 0.394 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.032298e-01 0.394 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.032298e-01 0.394 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 4.064562e-01 0.391 0 0
Potential therapeutics for SARS R-HSA-9679191 4.091629e-01 0.388 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 4.141520e-01 0.383 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 4.141520e-01 0.383 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.141520e-01 0.383 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 4.141520e-01 0.383 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 4.154488e-01 0.381 0 0
Ub-specific processing proteases R-HSA-5689880 4.158918e-01 0.381 0 0
Gluconeogenesis R-HSA-70263 4.175641e-01 0.379 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 4.177136e-01 0.379 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.177136e-01 0.379 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 4.177136e-01 0.379 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 4.177136e-01 0.379 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 4.201846e-01 0.377 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 4.201846e-01 0.377 0 0
PI3K/AKT activation R-HSA-198203 4.207130e-01 0.376 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 4.207130e-01 0.376 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 4.207130e-01 0.376 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 4.207130e-01 0.376 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 4.207130e-01 0.376 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 4.207130e-01 0.376 0 0
Maturation of spike protein R-HSA-9683686 4.207130e-01 0.376 0 0
MAPK3 (ERK1) activation R-HSA-110056 4.207130e-01 0.376 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 4.207130e-01 0.376 0 0
Josephin domain DUBs R-HSA-5689877 4.207130e-01 0.376 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 4.207130e-01 0.376 0 0
Receptor Mediated Mitophagy R-HSA-8934903 4.207130e-01 0.376 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 4.275435e-01 0.369 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.276750e-01 0.369 0 0
DNA Replication R-HSA-69306 4.280096e-01 0.369 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 4.286032e-01 0.368 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 4.320171e-01 0.364 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 4.320171e-01 0.364 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 4.327184e-01 0.364 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 4.343805e-01 0.362 0 0
Assembly of the pre-replicative complex R-HSA-68867 4.343805e-01 0.362 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 4.348881e-01 0.362 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.395668e-01 0.357 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 4.405455e-01 0.356 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 4.419422e-01 0.355 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 4.422162e-01 0.354 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 4.445475e-01 0.352 0 0
FGFR2b ligand binding and activation R-HSA-190377 4.445475e-01 0.352 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.445475e-01 0.352 0 0
vRNP Assembly R-HSA-192905 4.445475e-01 0.352 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 4.445475e-01 0.352 0 0
Transport of RCbl within the body R-HSA-9758890 4.445475e-01 0.352 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.445475e-01 0.352 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 4.445475e-01 0.352 0 0
PECAM1 interactions R-HSA-210990 4.445475e-01 0.352 0 0
Prostanoid ligand receptors R-HSA-391908 4.445475e-01 0.352 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 4.445475e-01 0.352 0 0
DAP12 signaling R-HSA-2424491 4.461307e-01 0.351 0 0
Activation of the pre-replicative complex R-HSA-68962 4.461307e-01 0.351 0 0
Neurotransmitter clearance R-HSA-112311 4.461307e-01 0.351 0 0
Signaling by NOTCH4 R-HSA-9013694 4.511209e-01 0.346 0 0
Chromatin organization R-HSA-4839726 4.559047e-01 0.341 0 0
Cellular response to starvation R-HSA-9711097 4.592768e-01 0.338 0 0
EGFR downregulation R-HSA-182971 4.600457e-01 0.337 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.600457e-01 0.337 0 0
Centrosome maturation R-HSA-380287 4.602505e-01 0.337 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.602505e-01 0.337 0 0
Protein ubiquitination R-HSA-8852135 4.602505e-01 0.337 0 0
HCMV Infection R-HSA-9609646 4.609373e-01 0.336 0 0
Neurexins and neuroligins R-HSA-6794361 4.612439e-01 0.336 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 4.612439e-01 0.336 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.612439e-01 0.336 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 4.666570e-01 0.331 0 0
DS-GAG biosynthesis R-HSA-2022923 4.674028e-01 0.330 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.674028e-01 0.330 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.674028e-01 0.330 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.674028e-01 0.330 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.674028e-01 0.330 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 4.674028e-01 0.330 0 0
Plasmalogen biosynthesis R-HSA-75896 4.674028e-01 0.330 0 0
NF-kB is activated and signals survival R-HSA-209560 4.674028e-01 0.330 0 0
ERKs are inactivated R-HSA-202670 4.674028e-01 0.330 0 0
Activation of RAC1 R-HSA-428540 4.674028e-01 0.330 0 0
UCH proteinases R-HSA-5689603 4.693273e-01 0.329 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.719462e-01 0.326 0 0
Smooth Muscle Contraction R-HSA-445355 4.719462e-01 0.326 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.722312e-01 0.326 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 4.737546e-01 0.324 0 0
Inwardly rectifying K+ channels R-HSA-1296065 4.737546e-01 0.324 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 4.737546e-01 0.324 0 0
Homology Directed Repair R-HSA-5693538 4.785315e-01 0.320 0 0
Unfolded Protein Response (UPR) R-HSA-381119 4.815721e-01 0.317 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 4.825872e-01 0.316 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 4.825872e-01 0.316 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 4.825872e-01 0.316 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 4.872508e-01 0.312 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 4.872508e-01 0.312 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 4.872508e-01 0.312 0 0
Activation of ATR in response to replication stress R-HSA-176187 4.872508e-01 0.312 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 4.872508e-01 0.312 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.872508e-01 0.312 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.872508e-01 0.312 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 4.874834e-01 0.312 0 0
p75NTR recruits signalling complexes R-HSA-209543 4.893189e-01 0.310 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.893189e-01 0.310 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.893189e-01 0.310 0 0
GRB2 events in EGFR signaling R-HSA-179812 4.893189e-01 0.310 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 4.893189e-01 0.310 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.893189e-01 0.310 0 0
MET activates RAS signaling R-HSA-8851805 4.893189e-01 0.310 0 0
Interleukin-15 signaling R-HSA-8983432 4.893189e-01 0.310 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.893189e-01 0.310 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 4.893189e-01 0.310 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 4.893189e-01 0.310 0 0
Regulation of IFNG signaling R-HSA-877312 4.893189e-01 0.310 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 4.893189e-01 0.310 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 4.893189e-01 0.310 0 0
HATs acetylate histones R-HSA-3214847 4.904911e-01 0.309 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.930533e-01 0.307 0 0
Signaling by NOTCH3 R-HSA-9012852 4.930533e-01 0.307 0 0
Cellular response to heat stress R-HSA-3371556 4.999857e-01 0.301 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 5.005287e-01 0.301 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 5.005287e-01 0.301 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 5.005287e-01 0.301 0 0
Heme degradation R-HSA-189483 5.005287e-01 0.301 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.034491e-01 0.298 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 5.034491e-01 0.298 0 0
Adenylate cyclase activating pathway R-HSA-170660 5.103345e-01 0.292 0 0
FGFR2c ligand binding and activation R-HSA-190375 5.103345e-01 0.292 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 5.103345e-01 0.292 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 5.103345e-01 0.292 0 0
FGFR4 ligand binding and activation R-HSA-190322 5.103345e-01 0.292 0 0
Frs2-mediated activation R-HSA-170968 5.103345e-01 0.292 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 5.103345e-01 0.292 0 0
Diseases of nucleotide metabolism R-HSA-9735804 5.103345e-01 0.292 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 5.103345e-01 0.292 0 0
FGFR3 mutant receptor activation R-HSA-2033514 5.103345e-01 0.292 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 5.103345e-01 0.292 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 5.103345e-01 0.292 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.103345e-01 0.292 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 5.135833e-01 0.289 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 5.135833e-01 0.289 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 5.135833e-01 0.289 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 5.135833e-01 0.289 0 0
Synthesis of PA R-HSA-1483166 5.137341e-01 0.289 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 5.264106e-01 0.279 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 5.264106e-01 0.279 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 5.293041e-01 0.276 0 0
Opioid Signalling R-HSA-111885 5.293041e-01 0.276 0 0
G alpha (q) signalling events R-HSA-416476 5.304277e-01 0.275 0 0
Retrograde neurotrophin signalling R-HSA-177504 5.304865e-01 0.275 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 5.304865e-01 0.275 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 5.304865e-01 0.275 0 0
NRIF signals cell death from the nucleus R-HSA-205043 5.304865e-01 0.275 0 0
FGFR3c ligand binding and activation R-HSA-190372 5.304865e-01 0.275 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.304865e-01 0.275 0 0
Hydrolysis of LPC R-HSA-1483115 5.304865e-01 0.275 0 0
Prolactin receptor signaling R-HSA-1170546 5.304865e-01 0.275 0 0
HDL assembly R-HSA-8963896 5.304865e-01 0.275 0 0
Signal regulatory protein family interactions R-HSA-391160 5.304865e-01 0.275 0 0
Acyl chain remodeling of CL R-HSA-1482798 5.304865e-01 0.275 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.304865e-01 0.275 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 5.339572e-01 0.272 0 0
RSV-host interactions R-HSA-9833110 5.369103e-01 0.270 0 0
RET signaling R-HSA-8853659 5.390071e-01 0.268 0 0
GPVI-mediated activation cascade R-HSA-114604 5.390071e-01 0.268 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 5.396419e-01 0.268 0 0
S Phase R-HSA-69242 5.463573e-01 0.263 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.481004e-01 0.261 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.498103e-01 0.260 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.498103e-01 0.260 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 5.498103e-01 0.260 0 0
p75NTR signals via NF-kB R-HSA-193639 5.498103e-01 0.260 0 0
Erythropoietin activates RAS R-HSA-9027284 5.498103e-01 0.260 0 0
FGFR3 ligand binding and activation R-HSA-190239 5.498103e-01 0.260 0 0
Translesion synthesis by REV1 R-HSA-110312 5.498103e-01 0.260 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 5.498103e-01 0.260 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.498103e-01 0.260 0 0
DCC mediated attractive signaling R-HSA-418885 5.498103e-01 0.260 0 0
p38MAPK events R-HSA-171007 5.498103e-01 0.260 0 0
Synthesis of 12-eicosatetraenoic acid derivatives R-HSA-2142712 5.498103e-01 0.260 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 5.498103e-01 0.260 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 5.498103e-01 0.260 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.498103e-01 0.260 0 0
Cleavage of the damaged purine R-HSA-110331 5.513702e-01 0.259 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.536964e-01 0.257 0 0
MAP kinase activation R-HSA-450294 5.536964e-01 0.257 0 0
Mitochondrial protein import R-HSA-1268020 5.633774e-01 0.249 0 0
tRNA processing in the nucleus R-HSA-6784531 5.633774e-01 0.249 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.633774e-01 0.249 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 5.634977e-01 0.249 0 0
Purine salvage R-HSA-74217 5.634977e-01 0.249 0 0
Depurination R-HSA-73927 5.634977e-01 0.249 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 5.634977e-01 0.249 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 5.667502e-01 0.247 0 0
Antigen processing-Cross presentation R-HSA-1236975 5.667502e-01 0.247 0 0
Translesion synthesis by POLI R-HSA-5656121 5.683400e-01 0.245 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.683400e-01 0.245 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.683400e-01 0.245 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 5.683400e-01 0.245 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.683400e-01 0.245 0 0
Phosphorylation of the APC/C R-HSA-176412 5.683400e-01 0.245 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.683400e-01 0.245 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.683400e-01 0.245 0 0
Prolonged ERK activation events R-HSA-169893 5.683400e-01 0.245 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.683400e-01 0.245 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.683400e-01 0.245 0 0
Killing mechanisms R-HSA-9664420 5.683400e-01 0.245 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.683400e-01 0.245 0 0
Fructose catabolism R-HSA-70350 5.683400e-01 0.245 0 0
Negative regulation of FLT3 R-HSA-9706369 5.683400e-01 0.245 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 5.683400e-01 0.245 0 0
Attachment and Entry R-HSA-9678110 5.683400e-01 0.245 0 0
Atorvastatin ADME R-HSA-9754706 5.683400e-01 0.245 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 5.713127e-01 0.243 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 5.729296e-01 0.242 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 5.729296e-01 0.242 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 5.740555e-01 0.241 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 5.753880e-01 0.240 0 0
Stabilization of p53 R-HSA-69541 5.753880e-01 0.240 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 5.753880e-01 0.240 0 0
Signaling by WNT R-HSA-195721 5.761973e-01 0.239 0 0
Insulin receptor signalling cascade R-HSA-74751 5.823508e-01 0.235 0 0
Ion transport by P-type ATPases R-HSA-936837 5.823508e-01 0.235 0 0
Translesion synthesis by POLK R-HSA-5655862 5.861080e-01 0.232 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.861080e-01 0.232 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 5.861080e-01 0.232 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 5.861080e-01 0.232 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.861080e-01 0.232 0 0
Scavenging by Class B Receptors R-HSA-3000471 5.861080e-01 0.232 0 0
Phase 2 - plateau phase R-HSA-5576893 5.861080e-01 0.232 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.861080e-01 0.232 0 0
Galactose catabolism R-HSA-70370 5.861080e-01 0.232 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.870401e-01 0.231 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 5.870401e-01 0.231 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 5.870401e-01 0.231 0 0
Diseases of Immune System R-HSA-5260271 5.870401e-01 0.231 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 5.870401e-01 0.231 0 0
PPARA activates gene expression R-HSA-1989781 5.896004e-01 0.229 0 0
Cellular response to hypoxia R-HSA-1234174 5.916392e-01 0.228 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 5.984536e-01 0.223 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.984536e-01 0.223 0 0
Maturation of spike protein R-HSA-9694548 5.984536e-01 0.223 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 6.015733e-01 0.221 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 6.026141e-01 0.220 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 6.031457e-01 0.220 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 6.031457e-01 0.220 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 6.031457e-01 0.220 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 6.031457e-01 0.220 0 0
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770 6.031457e-01 0.220 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 6.031457e-01 0.220 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 6.031457e-01 0.220 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 6.049132e-01 0.218 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 6.095817e-01 0.215 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 6.096282e-01 0.215 0 0
Kidney development R-HSA-9830369 6.098110e-01 0.215 0 0
Parasitic Infection Pathways R-HSA-9824443 6.105398e-01 0.214 0 0
Leishmania infection R-HSA-9658195 6.105398e-01 0.214 0 0
Signaling by TGFB family members R-HSA-9006936 6.191868e-01 0.208 0 0
GAB1 signalosome R-HSA-180292 6.194831e-01 0.208 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 6.194831e-01 0.208 0 0
Activated point mutants of FGFR2 R-HSA-2033519 6.194831e-01 0.208 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.194831e-01 0.208 0 0
PKA activation in glucagon signalling R-HSA-164378 6.194831e-01 0.208 0 0
Mismatch Repair R-HSA-5358508 6.194831e-01 0.208 0 0
PKA activation R-HSA-163615 6.194831e-01 0.208 0 0
Tie2 Signaling R-HSA-210993 6.194831e-01 0.208 0 0
Activation of GABAB receptors R-HSA-991365 6.205644e-01 0.207 0 0
GABA B receptor activation R-HSA-977444 6.205644e-01 0.207 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 6.205644e-01 0.207 0 0
Depyrimidination R-HSA-73928 6.205644e-01 0.207 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 6.233028e-01 0.205 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 6.274345e-01 0.202 0 0
Interferon alpha/beta signaling R-HSA-909733 6.300543e-01 0.201 0 0
DNA Repair R-HSA-73894 6.302099e-01 0.201 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.351488e-01 0.197 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 6.351488e-01 0.197 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 6.351488e-01 0.197 0 0
Germ layer formation at gastrulation R-HSA-9754189 6.351488e-01 0.197 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.351488e-01 0.197 0 0
Regulation of signaling by CBL R-HSA-912631 6.351488e-01 0.197 0 0
Specification of the neural plate border R-HSA-9834899 6.351488e-01 0.197 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.351488e-01 0.197 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 6.351488e-01 0.197 0 0
Translesion Synthesis by POLH R-HSA-110320 6.351488e-01 0.197 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 6.351488e-01 0.197 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.351488e-01 0.197 0 0
The NLRP3 inflammasome R-HSA-844456 6.351488e-01 0.197 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 6.351488e-01 0.197 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.351488e-01 0.197 0 0
Interleukin-17 signaling R-HSA-448424 6.360383e-01 0.197 0 0
DAP12 interactions R-HSA-2172127 6.417243e-01 0.193 0 0
RMTs methylate histone arginines R-HSA-3214858 6.417243e-01 0.193 0 0
Mitochondrial biogenesis R-HSA-1592230 6.433351e-01 0.192 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 6.445025e-01 0.191 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 6.501705e-01 0.187 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 6.501705e-01 0.187 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.501705e-01 0.187 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.501705e-01 0.187 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.501705e-01 0.187 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.501705e-01 0.187 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 6.501705e-01 0.187 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 6.501705e-01 0.187 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 6.501705e-01 0.187 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.501705e-01 0.187 0 0
Acyl chain remodelling of PI R-HSA-1482922 6.501705e-01 0.187 0 0
Keratan sulfate degradation R-HSA-2022857 6.501705e-01 0.187 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.501705e-01 0.187 0 0
Signaling by NODAL R-HSA-1181150 6.501705e-01 0.187 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 6.501705e-01 0.187 0 0
Glycogen synthesis R-HSA-3322077 6.501705e-01 0.187 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 6.619429e-01 0.179 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.619429e-01 0.179 0 0
Diseases of DNA repair R-HSA-9675135 6.619429e-01 0.179 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 6.645746e-01 0.177 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 6.645746e-01 0.177 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.645746e-01 0.177 0 0
FGFR2 ligand binding and activation R-HSA-190241 6.645746e-01 0.177 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.645746e-01 0.177 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.645746e-01 0.177 0 0
ERK/MAPK targets R-HSA-198753 6.645746e-01 0.177 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 6.645746e-01 0.177 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.645746e-01 0.177 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 6.645746e-01 0.177 0 0
Acyl chain remodelling of PG R-HSA-1482925 6.645746e-01 0.177 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 6.645746e-01 0.177 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 6.645746e-01 0.177 0 0
ROS and RNS production in phagocytes R-HSA-1222556 6.690540e-01 0.175 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 6.717035e-01 0.173 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 6.769569e-01 0.169 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.783865e-01 0.169 0 0
CS-GAG biosynthesis R-HSA-2022870 6.783865e-01 0.169 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 6.783865e-01 0.169 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 6.783865e-01 0.169 0 0
Attachment and Entry R-HSA-9694614 6.783865e-01 0.169 0 0
Ribavirin ADME R-HSA-9755088 6.783865e-01 0.169 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 6.812344e-01 0.167 0 0
ABC-family proteins mediated transport R-HSA-382556 6.848527e-01 0.164 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 6.851461e-01 0.164 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 6.905379e-01 0.161 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 6.905379e-01 0.161 0 0
DNA Damage Bypass R-HSA-73893 6.905379e-01 0.161 0 0
Interleukin-1 signaling R-HSA-9020702 6.915231e-01 0.160 0 0
Signaling by KIT in disease R-HSA-9669938 6.916304e-01 0.160 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 6.916304e-01 0.160 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 6.916304e-01 0.160 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 6.916304e-01 0.160 0 0
FGFR2 alternative splicing R-HSA-6803529 6.916304e-01 0.160 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 6.916304e-01 0.160 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 6.916304e-01 0.160 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 6.916304e-01 0.160 0 0
LDL clearance R-HSA-8964038 6.916304e-01 0.160 0 0
Fructose metabolism R-HSA-5652084 6.916304e-01 0.160 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 6.916304e-01 0.160 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.916304e-01 0.160 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 6.916304e-01 0.160 0 0
Regulation of endogenous retroelements R-HSA-9842860 6.980926e-01 0.156 0 0
PI3K Cascade R-HSA-109704 6.996167e-01 0.155 0 0
Azathioprine ADME R-HSA-9748787 6.996167e-01 0.155 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 6.998252e-01 0.155 0 0
Integrin cell surface interactions R-HSA-216083 6.998252e-01 0.155 0 0
SARS-CoV Infections R-HSA-9679506 7.028297e-01 0.153 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.043297e-01 0.152 0 0
Formation of the ureteric bud R-HSA-9830674 7.043297e-01 0.152 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 7.043297e-01 0.152 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 7.043297e-01 0.152 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 7.084734e-01 0.150 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 7.084734e-01 0.150 0 0
SARS-CoV-2-host interactions R-HSA-9705683 7.134385e-01 0.147 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 7.165068e-01 0.145 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.165068e-01 0.145 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.165068e-01 0.145 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.165068e-01 0.145 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 7.171108e-01 0.144 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 7.171108e-01 0.144 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.171108e-01 0.144 0 0
Generic Transcription Pathway R-HSA-212436 7.176620e-01 0.144 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.214425e-01 0.142 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.255322e-01 0.139 0 0
Regulation of PTEN stability and activity R-HSA-8948751 7.255322e-01 0.139 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.281831e-01 0.138 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 7.281831e-01 0.138 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 7.281831e-01 0.138 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.281831e-01 0.138 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.281831e-01 0.138 0 0
G protein gated Potassium channels R-HSA-1296059 7.281831e-01 0.138 0 0
TGFBR3 expression R-HSA-9839394 7.281831e-01 0.138 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 7.281831e-01 0.138 0 0
Laminin interactions R-HSA-3000157 7.281831e-01 0.138 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.281831e-01 0.138 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 7.281831e-01 0.138 0 0
Translation initiation complex formation R-HSA-72649 7.337405e-01 0.134 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 7.337405e-01 0.134 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 7.393792e-01 0.131 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 7.393792e-01 0.131 0 0
Abacavir ADME R-HSA-2161522 7.393792e-01 0.131 0 0
Suppression of phagosomal maturation R-HSA-9637687 7.393792e-01 0.131 0 0
G alpha (z) signalling events R-HSA-418597 7.417391e-01 0.130 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 7.495312e-01 0.125 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 7.501147e-01 0.125 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 7.501147e-01 0.125 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 7.501147e-01 0.125 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.501147e-01 0.125 0 0
Signaling by BMP R-HSA-201451 7.501147e-01 0.125 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 7.501147e-01 0.125 0 0
Triglyceride biosynthesis R-HSA-75109 7.501147e-01 0.125 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.501147e-01 0.125 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 7.501147e-01 0.125 0 0
Maturation of hRSV A proteins R-HSA-9828806 7.501147e-01 0.125 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 7.547486e-01 0.122 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.547486e-01 0.122 0 0
Viral Infection Pathways R-HSA-9824446 7.550835e-01 0.122 0 0
IRS-mediated signalling R-HSA-112399 7.571204e-01 0.121 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.604087e-01 0.119 0 0
HIV elongation arrest and recovery R-HSA-167287 7.604087e-01 0.119 0 0
Pausing and recovery of HIV elongation R-HSA-167290 7.604087e-01 0.119 0 0
Prednisone ADME R-HSA-9757110 7.604087e-01 0.119 0 0
Inflammasomes R-HSA-622312 7.604087e-01 0.119 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.645100e-01 0.117 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 7.645100e-01 0.117 0 0
Integration of energy metabolism R-HSA-163685 7.689099e-01 0.114 0 0
Phospholipid metabolism R-HSA-1483257 7.696170e-01 0.114 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.702792e-01 0.113 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 7.702792e-01 0.113 0 0
Platelet calcium homeostasis R-HSA-418360 7.702792e-01 0.113 0 0
Signaling by Erythropoietin R-HSA-9006335 7.702792e-01 0.113 0 0
Regulation of gene expression in beta cells R-HSA-210745 7.702792e-01 0.113 0 0
DARPP-32 events R-HSA-180024 7.702792e-01 0.113 0 0
Peroxisomal protein import R-HSA-9033241 7.717037e-01 0.113 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 7.717037e-01 0.113 0 0
Regulation of beta-cell development R-HSA-186712 7.717037e-01 0.113 0 0
SARS-CoV-2 Infection R-HSA-9694516 7.740442e-01 0.111 0 0
Selenoamino acid metabolism R-HSA-2408522 7.751169e-01 0.111 0 0
GABA receptor activation R-HSA-977443 7.787050e-01 0.109 0 0
Glutathione conjugation R-HSA-156590 7.787050e-01 0.109 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 7.797436e-01 0.108 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 7.797436e-01 0.108 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.797436e-01 0.108 0 0
Activation of BH3-only proteins R-HSA-114452 7.797436e-01 0.108 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.797436e-01 0.108 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.797436e-01 0.108 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.797436e-01 0.108 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 7.797436e-01 0.108 0 0
Mucopolysaccharidoses R-HSA-2206281 7.797436e-01 0.108 0 0
Base Excision Repair R-HSA-73884 7.847736e-01 0.105 0 0
Formation of paraxial mesoderm R-HSA-9793380 7.855176e-01 0.105 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.855176e-01 0.105 0 0
Nucleotide salvage R-HSA-8956321 7.855176e-01 0.105 0 0
Collagen degradation R-HSA-1442490 7.855176e-01 0.105 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 7.888187e-01 0.103 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 7.888187e-01 0.103 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 7.888187e-01 0.103 0 0
Cargo concentration in the ER R-HSA-5694530 7.888187e-01 0.103 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.888187e-01 0.103 0 0
Molecules associated with elastic fibres R-HSA-2129379 7.888187e-01 0.103 0 0
Downstream signal transduction R-HSA-186763 7.888187e-01 0.103 0 0
RNA Polymerase II Transcription R-HSA-73857 7.893858e-01 0.103 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 7.896695e-01 0.103 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 7.921452e-01 0.101 0 0
Heme signaling R-HSA-9707616 7.921452e-01 0.101 0 0
Neddylation R-HSA-8951664 7.921860e-01 0.101 0 0
HS-GAG degradation R-HSA-2024096 7.975203e-01 0.098 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.975203e-01 0.098 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.975203e-01 0.098 0 0
Signaling by Insulin receptor R-HSA-74752 8.012858e-01 0.096 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 8.058640e-01 0.094 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 8.058640e-01 0.094 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 8.058640e-01 0.094 0 0
Nuclear RNA decay R-HSA-9930044 8.058640e-01 0.094 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 8.058640e-01 0.094 0 0
FGFR1 mutant receptor activation R-HSA-1839124 8.058640e-01 0.094 0 0
Cardiogenesis R-HSA-9733709 8.058640e-01 0.094 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 8.058640e-01 0.094 0 0
Collagen formation R-HSA-1474290 8.116937e-01 0.091 0 0
Resolution of D-Loop Structures R-HSA-5693537 8.138643e-01 0.089 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 8.138643e-01 0.089 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.138643e-01 0.089 0 0
CS/DS degradation R-HSA-2024101 8.138643e-01 0.089 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.138643e-01 0.089 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 8.138643e-01 0.089 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 8.215354e-01 0.085 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.215354e-01 0.085 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.215354e-01 0.085 0 0
eNOS activation R-HSA-203615 8.215354e-01 0.085 0 0
Nuclear import of Rev protein R-HSA-180746 8.215354e-01 0.085 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 8.215354e-01 0.085 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 8.215354e-01 0.085 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 8.215354e-01 0.085 0 0
Calnexin/calreticulin cycle R-HSA-901042 8.215354e-01 0.085 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.215354e-01 0.085 0 0
Signal amplification R-HSA-392518 8.215354e-01 0.085 0 0
Signaling by NOTCH2 R-HSA-1980145 8.215354e-01 0.085 0 0
Gene expression (Transcription) R-HSA-74160 8.259015e-01 0.083 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.288908e-01 0.082 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.288908e-01 0.082 0 0
PERK regulates gene expression R-HSA-381042 8.288908e-01 0.082 0 0
Telomere Maintenance R-HSA-157579 8.311296e-01 0.080 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 8.311296e-01 0.080 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 8.359434e-01 0.078 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.359434e-01 0.078 0 0
Glycosphingolipid transport R-HSA-9845576 8.359434e-01 0.078 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.359434e-01 0.078 0 0
Keratinization R-HSA-6805567 8.359762e-01 0.078 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 8.427058e-01 0.074 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 8.427058e-01 0.074 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 8.427058e-01 0.074 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 8.427058e-01 0.074 0 0
Post-translational protein modification R-HSA-597592 8.438949e-01 0.074 0 0
Metabolism of porphyrins R-HSA-189445 8.440718e-01 0.074 0 0
Protein localization R-HSA-9609507 8.441110e-01 0.074 0 0
Purine catabolism R-HSA-74259 8.490505e-01 0.071 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 8.490505e-01 0.071 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 8.490505e-01 0.071 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 8.491898e-01 0.071 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 8.491898e-01 0.071 0 0
MET promotes cell motility R-HSA-8875878 8.491898e-01 0.071 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 8.491898e-01 0.071 0 0
Elastic fibre formation R-HSA-1566948 8.491898e-01 0.071 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.491898e-01 0.071 0 0
Ca2+ pathway R-HSA-4086398 8.538842e-01 0.069 0 0
Switching of origins to a post-replicative state R-HSA-69052 8.538842e-01 0.069 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 8.538842e-01 0.069 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 8.554070e-01 0.068 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 8.554070e-01 0.068 0 0
Plasma lipoprotein clearance R-HSA-8964043 8.554070e-01 0.068 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.554070e-01 0.068 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 8.613682e-01 0.065 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.613682e-01 0.065 0 0
HIV Transcription Elongation R-HSA-167169 8.613682e-01 0.065 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 8.613682e-01 0.065 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 8.613682e-01 0.065 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 8.613682e-01 0.065 0 0
Glycogen metabolism R-HSA-8982491 8.613682e-01 0.065 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 8.631303e-01 0.064 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 8.631303e-01 0.064 0 0
Interferon gamma signaling R-HSA-877300 8.642058e-01 0.063 0 0
Metabolism of RNA R-HSA-8953854 8.665556e-01 0.062 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 8.670652e-01 0.062 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 8.670839e-01 0.062 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 8.670839e-01 0.062 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 8.670839e-01 0.062 0 0
Circadian clock R-HSA-9909396 8.680007e-01 0.061 0 0
Translation of Structural Proteins R-HSA-9694635 8.718376e-01 0.060 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.725644e-01 0.059 0 0
Signaling by FGFR1 in disease R-HSA-5655302 8.725644e-01 0.059 0 0
Translation of Structural Proteins R-HSA-9683701 8.725644e-01 0.059 0 0
Disease R-HSA-1643685 8.734267e-01 0.059 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 8.778192e-01 0.057 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.778192e-01 0.057 0 0
MTOR signalling R-HSA-165159 8.778192e-01 0.057 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.778192e-01 0.057 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.778192e-01 0.057 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 8.800327e-01 0.056 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 8.828576e-01 0.054 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 8.828576e-01 0.054 0 0
Response of Mtb to phagocytosis R-HSA-9637690 8.828576e-01 0.054 0 0
Signaling by MET R-HSA-6806834 8.839464e-01 0.054 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 8.876886e-01 0.052 0 0
Surfactant metabolism R-HSA-5683826 8.876886e-01 0.052 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 8.876886e-01 0.052 0 0
Asparagine N-linked glycosylation R-HSA-446203 8.886822e-01 0.051 0 0
GPCR downstream signalling R-HSA-388396 8.917865e-01 0.050 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 8.923206e-01 0.049 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 8.923206e-01 0.049 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.923206e-01 0.049 0 0
Nucleosome assembly R-HSA-774815 8.923206e-01 0.049 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 8.923206e-01 0.049 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 8.923206e-01 0.049 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 8.923206e-01 0.049 0 0
Fanconi Anemia Pathway R-HSA-6783310 8.923206e-01 0.049 0 0
Somitogenesis R-HSA-9824272 8.923206e-01 0.049 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 8.923206e-01 0.049 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.923206e-01 0.049 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 8.923206e-01 0.049 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.949892e-01 0.048 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 8.967618e-01 0.047 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.967618e-01 0.047 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.967618e-01 0.047 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 8.984476e-01 0.047 0 0
G alpha (s) signalling events R-HSA-418555 9.003563e-01 0.046 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.010201e-01 0.045 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.010201e-01 0.045 0 0
Synthesis of PC R-HSA-1483191 9.010201e-01 0.045 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.010201e-01 0.045 0 0
NGF-stimulated transcription R-HSA-9031628 9.051030e-01 0.043 0 0
Keratan sulfate/keratin metabolism R-HSA-1638074 9.090178e-01 0.041 0 0
Rab regulation of trafficking R-HSA-9007101 9.124643e-01 0.040 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.127712e-01 0.040 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.163701e-01 0.038 0 0
ER-Phagosome pathway R-HSA-1236974 9.170641e-01 0.038 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 9.175065e-01 0.037 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 9.198207e-01 0.036 0 0
Orc1 removal from chromatin R-HSA-68949 9.198207e-01 0.036 0 0
Neurotransmitter release cycle R-HSA-112310 9.198367e-01 0.036 0 0
Downstream TCR signaling R-HSA-202424 9.198367e-01 0.036 0 0
Gastrulation R-HSA-9758941 9.198653e-01 0.036 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.222827e-01 0.035 0 0
Chromosome Maintenance R-HSA-73886 9.222827e-01 0.035 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 9.231291e-01 0.035 0 0
Extracellular matrix organization R-HSA-1474244 9.233431e-01 0.035 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.263012e-01 0.033 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.276404e-01 0.033 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.276404e-01 0.033 0 0
Host Interactions of HIV factors R-HSA-162909 9.289742e-01 0.032 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.293425e-01 0.032 0 0
Paracetamol ADME R-HSA-9753281 9.293425e-01 0.032 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 9.322586e-01 0.030 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 9.322586e-01 0.030 0 0
Mitochondrial protein degradation R-HSA-9837999 9.324384e-01 0.030 0 0
Dectin-2 family R-HSA-5621480 9.350545e-01 0.029 0 0
HCMV Late Events R-HSA-9610379 9.356080e-01 0.029 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.377351e-01 0.028 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.390746e-01 0.027 0 0
Metabolism of non-coding RNA R-HSA-194441 9.403052e-01 0.027 0 0
snRNP Assembly R-HSA-191859 9.403052e-01 0.027 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.403052e-01 0.027 0 0
Triglyceride metabolism R-HSA-8979227 9.403052e-01 0.027 0 0
tRNA Aminoacylation R-HSA-379724 9.427695e-01 0.026 0 0
Regulation of insulin secretion R-HSA-422356 9.431500e-01 0.025 0 0
Viral Messenger RNA Synthesis R-HSA-168325 9.451321e-01 0.025 0 0
Aquaporin-mediated transport R-HSA-445717 9.451321e-01 0.025 0 0
Signaling by PDGF R-HSA-186797 9.473973e-01 0.023 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.476357e-01 0.023 0 0
Signaling by GPCR R-HSA-372790 9.484265e-01 0.023 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.495692e-01 0.022 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.516515e-01 0.022 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 9.551523e-01 0.020 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.555621e-01 0.020 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.559376e-01 0.020 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.559376e-01 0.020 0 0
tRNA processing R-HSA-72306 9.565591e-01 0.019 0 0
Nucleotide Excision Repair R-HSA-5696398 9.570010e-01 0.019 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 9.573973e-01 0.019 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.573973e-01 0.019 0 0
Transcription of the HIV genome R-HSA-167172 9.591568e-01 0.018 0 0
Synthesis of DNA R-HSA-69239 9.599222e-01 0.018 0 0
COPII-mediated vesicle transport R-HSA-204005 9.624611e-01 0.017 0 0
TCR signaling R-HSA-202403 9.639501e-01 0.016 0 0
ECM proteoglycans R-HSA-3000178 9.640117e-01 0.016 0 0
Metabolism of cofactors R-HSA-8978934 9.640117e-01 0.016 0 0
Retinoid metabolism and transport R-HSA-975634 9.640117e-01 0.016 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 9.654984e-01 0.015 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.662011e-01 0.015 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.664162e-01 0.015 0 0
Inositol phosphate metabolism R-HSA-1483249 9.664162e-01 0.015 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 9.672267e-01 0.014 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 9.682904e-01 0.014 0 0
Signaling by FGFR in disease R-HSA-1226099 9.682904e-01 0.014 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 9.696005e-01 0.013 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.718921e-01 0.012 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.720610e-01 0.012 0 0
MITF-M-dependent gene expression R-HSA-9856651 9.720829e-01 0.012 0 0
ABC transporter disorders R-HSA-5619084 9.732156e-01 0.012 0 0
PCP/CE pathway R-HSA-4086400 9.732156e-01 0.012 0 0
Cholesterol biosynthesis R-HSA-191273 9.732156e-01 0.012 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.738181e-01 0.012 0 0
Peptide hormone metabolism R-HSA-2980736 9.738321e-01 0.012 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.743225e-01 0.011 0 0
Infectious disease R-HSA-5663205 9.754137e-01 0.011 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.764012e-01 0.010 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.783119e-01 0.010 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.792085e-01 0.009 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.817464e-01 0.008 0 0
Metabolism of nucleotides R-HSA-15869 9.827348e-01 0.008 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.831659e-01 0.007 0 0
Nucleotide catabolism R-HSA-8956319 9.836288e-01 0.007 0 0
SLC transporter disorders R-HSA-5619102 9.839257e-01 0.007 0 0
G alpha (i) signalling events R-HSA-418594 9.853417e-01 0.006 0 0
FCGR activation R-HSA-2029481 9.869348e-01 0.006 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.872457e-01 0.006 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.872457e-01 0.006 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.899368e-01 0.004 0 0
Drug ADME R-HSA-9748784 9.899872e-01 0.004 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.907923e-01 0.004 0 0
Late Phase of HIV Life Cycle R-HSA-162599 9.908889e-01 0.004 0 0
Metabolism of proteins R-HSA-392499 9.911552e-01 0.004 0 0
Translation R-HSA-72766 9.913018e-01 0.004 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 9.914381e-01 0.004 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.932246e-01 0.003 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.934897e-01 0.003 0 0
Arachidonate metabolism R-HSA-2142753 9.937101e-01 0.003 0 0
Antimicrobial peptides R-HSA-6803157 9.943907e-01 0.002 0 0
HIV Life Cycle R-HSA-162587 9.947797e-01 0.002 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.954602e-01 0.002 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.960147e-01 0.002 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.966243e-01 0.001 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.968984e-01 0.001 0 0
Regulation of Complement cascade R-HSA-977606 9.971502e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.975101e-01 0.001 0 0
Respiratory electron transport R-HSA-611105 9.977192e-01 0.001 0 0
Sensory perception of taste R-HSA-9717189 9.979693e-01 0.001 0 0
HIV Infection R-HSA-162906 9.980623e-01 0.001 0 0
Diseases of glycosylation R-HSA-3781865 9.981840e-01 0.001 0 0
Peptide ligand-binding receptors R-HSA-375276 9.983171e-01 0.001 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.986389e-01 0.001 0 0
Complement cascade R-HSA-166658 9.989694e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.990532e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.996991e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.997908e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.998336e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.998676e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.998807e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.998955e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999626e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999745e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999967e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999977e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999986e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999998e-01 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Cap-dependent Translation Initiation R-HSA-72737 1.110223e-16 15.955 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.220446e-16 15.654 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.220446e-16 15.654 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.110223e-15 14.955 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.221245e-15 14.913 0 0
Ribosome-associated quality control R-HSA-9948299 1.443290e-15 14.841 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.665335e-15 14.778 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.887379e-15 14.724 0 0
Aggrephagy R-HSA-9646399 2.331468e-15 14.632 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 2.775558e-15 14.557 0 0
Peptide chain elongation R-HSA-156902 2.886580e-15 14.540 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 4.329870e-15 14.364 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.769963e-15 14.010 0 0
Metabolism of RNA R-HSA-8953854 1.465494e-14 13.834 0 0
Formation of a pool of free 40S subunits R-HSA-72689 2.486900e-14 13.604 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 4.352074e-14 13.361 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 6.439294e-14 13.191 0 0
Cell Cycle R-HSA-1640170 8.493206e-14 13.071 0 0
Post NMDA receptor activation events R-HSA-438064 1.200151e-13 12.921 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 1.709743e-13 12.767 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 1.709743e-13 12.767 0 0
HSF1-dependent transactivation R-HSA-3371571 1.769696e-13 12.752 0 0
Eukaryotic Translation Termination R-HSA-72764 1.671996e-13 12.777 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.734168e-13 12.761 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.171596e-13 12.663 0 0
Cell Cycle, Mitotic R-HSA-69278 3.924638e-13 12.406 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 4.161116e-13 12.381 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 5.649925e-13 12.248 0 0
Selenocysteine synthesis R-HSA-2408557 5.885292e-13 12.230 0 0
Viral Infection Pathways R-HSA-9824446 5.889733e-13 12.230 0 0
Viral mRNA Translation R-HSA-192823 8.797407e-13 12.056 0 0
Cell-Cell communication R-HSA-1500931 8.644196e-13 12.063 0 0
SARS-CoV-1 Infection R-HSA-9678108 8.583134e-13 12.066 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 9.110490e-13 12.040 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 1.050937e-12 11.978 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.139200e-12 11.943 0 0
Cellular response to heat stress R-HSA-3371556 1.323608e-12 11.878 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.429967e-12 11.845 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.886380e-12 11.724 0 0
Signaling by ROBO receptors R-HSA-376176 1.873057e-12 11.727 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.392286e-12 11.470 0 0
Translation initiation complex formation R-HSA-72649 3.817502e-12 11.418 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 3.772871e-12 11.423 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 4.365397e-12 11.360 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 5.637601e-12 11.249 0 0
Selective autophagy R-HSA-9663891 6.701417e-12 11.174 0 0
Influenza Infection R-HSA-168255 6.809553e-12 11.167 0 0
Cell junction organization R-HSA-446728 1.160017e-11 10.936 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.602163e-11 10.795 0 0
Attenuation phase R-HSA-3371568 2.758760e-11 10.559 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 2.698819e-11 10.569 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 4.192124e-11 10.378 0 0
PKR-mediated signaling R-HSA-9833482 4.144940e-11 10.382 0 0
Mitotic Anaphase R-HSA-68882 4.248468e-11 10.372 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 4.762613e-11 10.322 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 5.251055e-11 10.280 0 0
Signal Transduction R-HSA-162582 7.005507e-11 10.155 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 7.856160e-11 10.105 0 0
Developmental Biology R-HSA-1266738 1.266703e-10 9.897 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.319250e-10 9.880 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 1.752238e-10 9.756 0 0
Chaperonin-mediated protein folding R-HSA-390466 2.076281e-10 9.683 0 0
Apoptosis R-HSA-109581 2.371743e-10 9.625 0 0
rRNA processing R-HSA-72312 2.454005e-10 9.610 0 0
G2/M Transition R-HSA-69275 2.960626e-10 9.529 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.743770e-10 9.427 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 4.154668e-10 9.381 0 0
Translation R-HSA-72766 4.749241e-10 9.323 0 0
Cellular response to starvation R-HSA-9711097 6.103524e-10 9.214 0 0
Protein folding R-HSA-391251 6.278631e-10 9.202 0 0
HSF1 activation R-HSA-3371511 6.525169e-10 9.185 0 0
Gap junction trafficking R-HSA-190828 1.045056e-09 8.981 0 0
Kinesins R-HSA-983189 1.003805e-09 8.998 0 0
Interferon Signaling R-HSA-913531 1.142538e-09 8.942 0 0
Selenoamino acid metabolism R-HSA-2408522 1.284740e-09 8.891 0 0
Signaling by RAS mutants R-HSA-6802949 1.773346e-09 8.751 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.773346e-09 8.751 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.773346e-09 8.751 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.773346e-09 8.751 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 1.773346e-09 8.751 0 0
Signaling by PTK6 R-HSA-8848021 1.950123e-09 8.710 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.950123e-09 8.710 0 0
Autophagy R-HSA-9612973 2.003639e-09 8.698 0 0
SARS-CoV-2-host interactions R-HSA-9705683 2.152124e-09 8.667 0 0
L1CAM interactions R-HSA-373760 2.161934e-09 8.665 0 0
Recycling pathway of L1 R-HSA-437239 2.290881e-09 8.640 0 0
Infectious disease R-HSA-5663205 2.654735e-09 8.576 0 0
Programmed Cell Death R-HSA-5357801 2.723199e-09 8.565 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.982028e-09 8.525 0 0
Gap junction assembly R-HSA-190861 3.150636e-09 8.502 0 0
Signaling by RAF1 mutants R-HSA-9656223 3.698076e-09 8.432 0 0
Gap junction trafficking and regulation R-HSA-157858 3.763700e-09 8.424 0 0
Macroautophagy R-HSA-1632852 4.823477e-09 8.317 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 5.563501e-09 8.255 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 6.593222e-09 8.181 0 0
Mitotic Prometaphase R-HSA-68877 9.529376e-09 8.021 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 1.198007e-08 7.922 0 0
Apoptotic execution phase R-HSA-75153 1.317411e-08 7.880 0 0
MAPK family signaling cascades R-HSA-5683057 1.565367e-08 7.805 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.592596e-08 7.798 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.592596e-08 7.798 0 0
Mitotic Prophase R-HSA-68875 1.743421e-08 7.759 0 0
Regulation of CDH1 Function R-HSA-9764561 2.280199e-08 7.642 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.831080e-08 7.417 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 6.027549e-08 7.220 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 5.652625e-08 7.248 0 0
Chaperone Mediated Autophagy R-HSA-9613829 6.233807e-08 7.205 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.742457e-08 7.171 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 7.447954e-08 7.128 0 0
Separation of Sister Chromatids R-HSA-2467813 7.671012e-08 7.115 0 0
EPH-Ephrin signaling R-HSA-2682334 8.787677e-08 7.056 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 9.097642e-08 7.041 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.097941e-07 6.959 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.082393e-07 6.966 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.142625e-07 6.942 0 0
Membrane Trafficking R-HSA-199991 1.238399e-07 6.907 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.293134e-07 6.888 0 0
Interleukin-12 signaling R-HSA-9020591 1.329990e-07 6.876 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.396864e-07 6.855 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.438186e-07 6.842 0 0
HCMV Early Events R-HSA-9609690 1.580833e-07 6.801 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.580833e-07 6.801 0 0
Cell-cell junction organization R-HSA-421270 1.825101e-07 6.739 0 0
MAP2K and MAPK activation R-HSA-5674135 2.028867e-07 6.693 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.540477e-07 6.451 0 0
Platelet activation, signaling and aggregation R-HSA-76002 3.603236e-07 6.443 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 4.435012e-07 6.353 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 4.625958e-07 6.335 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 4.980324e-07 6.303 0 0
Immune System R-HSA-168256 5.148280e-07 6.288 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 5.679768e-07 6.246 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 6.746271e-07 6.171 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 7.257118e-07 6.139 0 0
G2/M Checkpoints R-HSA-69481 7.860217e-07 6.105 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.555753e-07 6.122 0 0
Interleukin-12 family signaling R-HSA-447115 8.209501e-07 6.086 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.716801e-07 6.060 0 0
Cilium Assembly R-HSA-5617833 1.005685e-06 5.998 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.103817e-06 5.957 0 0
Hemostasis R-HSA-109582 1.118478e-06 5.951 0 0
Adherens junctions interactions R-HSA-418990 1.137393e-06 5.944 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.348296e-06 5.870 0 0
Hedgehog 'off' state R-HSA-5610787 1.349211e-06 5.870 0 0
Transmission across Chemical Synapses R-HSA-112315 1.371786e-06 5.863 0 0
Signaling by ERBB2 R-HSA-1227986 1.373994e-06 5.862 0 0
HCMV Infection R-HSA-9609646 1.491367e-06 5.826 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.496939e-06 5.825 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.824693e-06 5.739 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.824693e-06 5.739 0 0
Neutrophil degranulation R-HSA-6798695 2.240710e-06 5.650 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.463065e-06 5.609 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.758050e-06 5.559 0 0
Signaling by Hedgehog R-HSA-5358351 3.030632e-06 5.518 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.425248e-06 5.465 0 0
COPI-mediated anterograde transport R-HSA-6807878 3.438376e-06 5.464 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 3.598999e-06 5.444 0 0
mRNA Splicing - Major Pathway R-HSA-72163 4.391399e-06 5.357 0 0
Signaling by WNT R-HSA-195721 5.115107e-06 5.291 0 0
Intraflagellar transport R-HSA-5620924 5.173074e-06 5.286 0 0
Gluconeogenesis R-HSA-70263 5.173074e-06 5.286 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 5.193655e-06 5.285 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 5.372192e-06 5.270 0 0
Glycolysis R-HSA-70171 5.525007e-06 5.258 0 0
Organelle biogenesis and maintenance R-HSA-1852241 7.609093e-06 5.119 0 0
Signaling by EGFR in Cancer R-HSA-1643713 9.522959e-06 5.021 0 0
Metalloprotease DUBs R-HSA-5689901 9.522959e-06 5.021 0 0
Estrogen-dependent gene expression R-HSA-9018519 8.651794e-06 5.063 0 0
Signaling by VEGF R-HSA-194138 8.638770e-06 5.064 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 9.444840e-06 5.025 0 0
SARS-CoV Infections R-HSA-9679506 9.637099e-06 5.016 0 0
mRNA Splicing R-HSA-72172 1.020238e-05 4.991 0 0
Platelet degranulation R-HSA-114608 1.049313e-05 4.979 0 0
Disease R-HSA-1643685 1.105935e-05 4.956 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.123728e-05 4.949 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.201176e-05 4.920 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 1.268614e-05 4.897 0 0
RMTs methylate histone arginines R-HSA-3214858 1.425919e-05 4.846 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.723105e-05 4.764 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.723105e-05 4.764 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.723105e-05 4.764 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.914753e-05 4.718 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.996454e-05 4.700 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.996454e-05 4.700 0 0
MHC class II antigen presentation R-HSA-2132295 2.249613e-05 4.648 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 2.380097e-05 4.623 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.641066e-05 4.578 0 0
Amyloid fiber formation R-HSA-977225 2.729921e-05 4.564 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.008640e-05 4.522 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 3.236250e-05 4.490 0 0
ESR-mediated signaling R-HSA-8939211 3.533665e-05 4.452 0 0
Vesicle-mediated transport R-HSA-5653656 3.904481e-05 4.408 0 0
Cellular Senescence R-HSA-2559583 3.916256e-05 4.407 0 0
FLT3 Signaling R-HSA-9607240 3.934215e-05 4.405 0 0
Signaling by Interleukins R-HSA-449147 3.947700e-05 4.404 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 4.292277e-05 4.367 0 0
Meiosis R-HSA-1500620 4.357030e-05 4.361 0 0
Glucose metabolism R-HSA-70326 4.375515e-05 4.359 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 4.413130e-05 4.355 0 0
TCF dependent signaling in response to WNT R-HSA-201681 4.861974e-05 4.313 0 0
Cell Cycle Checkpoints R-HSA-69620 4.972467e-05 4.303 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 5.144683e-05 4.289 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 5.144683e-05 4.289 0 0
Semaphorin interactions R-HSA-373755 5.144683e-05 4.289 0 0
Adaptive Immune System R-HSA-1280218 5.247075e-05 4.280 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.282387e-05 4.202 0 0
RAF activation R-HSA-5673000 6.410337e-05 4.193 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 6.717752e-05 4.173 0 0
Diseases of programmed cell death R-HSA-9645723 6.776798e-05 4.169 0 0
HATs acetylate histones R-HSA-3214847 7.063698e-05 4.151 0 0
Regulation of signaling by CBL R-HSA-912631 7.417539e-05 4.130 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 7.490584e-05 4.125 0 0
AURKA Activation by TPX2 R-HSA-8854518 7.573598e-05 4.121 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 8.270231e-05 4.082 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 9.159441e-05 4.038 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.062509e-04 3.974 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.191386e-04 3.924 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 1.184026e-04 3.927 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.197649e-04 3.922 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 1.062509e-04 3.974 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 1.208857e-04 3.918 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 1.233431e-04 3.909 0 0
DNA methylation R-HSA-5334118 1.233431e-04 3.909 0 0
Late endosomal microautophagy R-HSA-9615710 1.233431e-04 3.909 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.258137e-04 3.900 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.382200e-04 3.859 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.491366e-04 3.826 0 0
Co-inhibition by PD-1 R-HSA-389948 1.518165e-04 3.819 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 1.522949e-04 3.817 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.522949e-04 3.817 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.582369e-04 3.801 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.582369e-04 3.801 0 0
Spry regulation of FGF signaling R-HSA-1295596 1.582369e-04 3.801 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.587428e-04 3.799 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.734228e-04 3.761 0 0
Neuronal System R-HSA-112316 1.807831e-04 3.743 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.818189e-04 3.740 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.840704e-04 3.735 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.946503e-04 3.711 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.963469e-04 3.707 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 2.060662e-04 3.686 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 2.374231e-04 3.624 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 2.374231e-04 3.624 0 0
Centrosome maturation R-HSA-380287 2.160137e-04 3.666 0 0
Josephin domain DUBs R-HSA-5689877 2.290541e-04 3.640 0 0
UCH proteinases R-HSA-5689603 2.404536e-04 3.619 0 0
Meiotic recombination R-HSA-912446 2.080664e-04 3.682 0 0
Negative regulation of FLT3 R-HSA-9706369 2.079877e-04 3.682 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 2.160137e-04 3.666 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.247480e-04 3.648 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 2.543961e-04 3.594 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 2.700130e-04 3.569 0 0
Meiotic synapsis R-HSA-1221632 2.701739e-04 3.568 0 0
PCP/CE pathway R-HSA-4086400 2.964466e-04 3.528 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 2.998946e-04 3.523 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.101959e-04 3.508 0 0
Response of Mtb to phagocytosis R-HSA-9637690 3.194170e-04 3.496 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 3.208559e-04 3.494 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 3.208559e-04 3.494 0 0
DNA Double Strand Break Response R-HSA-5693606 3.467381e-04 3.460 0 0
Long-term potentiation R-HSA-9620244 3.482956e-04 3.458 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 3.536097e-04 3.451 0 0
Maturation of protein E R-HSA-9683683 3.703234e-04 3.431 0 0
Maturation of protein E R-HSA-9694493 3.703234e-04 3.431 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 3.868326e-04 3.412 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 3.888014e-04 3.410 0 0
Signaling by EGFR R-HSA-177929 3.919079e-04 3.407 0 0
Processing of DNA double-strand break ends R-HSA-5693607 4.009659e-04 3.397 0 0
Ephrin signaling R-HSA-3928664 4.340203e-04 3.362 0 0
Metabolism of proteins R-HSA-392499 4.342846e-04 3.362 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.381164e-04 3.358 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.381164e-04 3.358 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.381164e-04 3.358 0 0
Nuclear Envelope Breakdown R-HSA-2980766 4.414447e-04 3.355 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 4.787644e-04 3.320 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 4.787644e-04 3.320 0 0
PRC2 methylates histones and DNA R-HSA-212300 4.822735e-04 3.317 0 0
FLT3 signaling in disease R-HSA-9682385 4.822735e-04 3.317 0 0
Ub-specific processing proteases R-HSA-5689880 4.986615e-04 3.302 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 5.031651e-04 3.298 0 0
Translesion Synthesis by POLH R-HSA-110320 5.414141e-04 3.266 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 5.561938e-04 3.255 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 5.595332e-04 3.252 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 5.850751e-04 3.233 0 0
p75NTR recruits signalling complexes R-HSA-209543 5.850751e-04 3.233 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.873605e-04 3.231 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 5.883018e-04 3.230 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 5.883018e-04 3.230 0 0
Signaling by NOTCH R-HSA-157118 6.293766e-04 3.201 0 0
Nephrin family interactions R-HSA-373753 6.683952e-04 3.175 0 0
Negative regulation of MET activity R-HSA-6807004 6.683952e-04 3.175 0 0
Degradation of CDH1 R-HSA-9766229 7.015687e-04 3.154 0 0
Signaling by ERBB4 R-HSA-1236394 7.179818e-04 3.144 0 0
Signaling by NOTCH4 R-HSA-9013694 7.179818e-04 3.144 0 0
Regulation of PTEN localization R-HSA-8948747 8.476487e-04 3.072 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 8.531266e-04 3.069 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 8.531266e-04 3.069 0 0
Host Interactions of HIV factors R-HSA-162909 7.530242e-04 3.123 0 0
RAS processing R-HSA-9648002 7.440625e-04 3.128 0 0
Signaling by Nuclear Receptors R-HSA-9006931 7.415843e-04 3.130 0 0
DNA Replication R-HSA-69306 9.171038e-04 3.038 0 0
Activation of BH3-only proteins R-HSA-114452 8.333934e-04 3.079 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 7.737628e-04 3.111 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.746594e-04 3.011 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 9.746594e-04 3.011 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 9.746594e-04 3.011 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.746594e-04 3.011 0 0
EGFR downregulation R-HSA-182971 9.750749e-04 3.011 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.750749e-04 3.011 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 9.750749e-04 3.011 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 9.862274e-04 3.006 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 9.905462e-04 3.004 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 9.905462e-04 3.004 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 9.905462e-04 3.004 0 0
Innate Immune System R-HSA-168249 1.023164e-03 2.990 0 0
Chromatin modifying enzymes R-HSA-3247509 1.066620e-03 2.972 0 0
Smooth Muscle Contraction R-HSA-445355 1.120182e-03 2.951 0 0
mTORC1-mediated signalling R-HSA-166208 1.190716e-03 2.924 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 1.190716e-03 2.924 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 1.201749e-03 2.920 0 0
Modulation by Mtb of host immune system R-HSA-9637628 1.201749e-03 2.920 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 1.249991e-03 2.903 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.249991e-03 2.903 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.249991e-03 2.903 0 0
p75NTR signals via NF-kB R-HSA-193639 1.249991e-03 2.903 0 0
Signaling by FGFR2 R-HSA-5654738 1.256770e-03 2.901 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.259197e-03 2.900 0 0
Clathrin-mediated endocytosis R-HSA-8856828 1.284459e-03 2.891 0 0
Deubiquitination R-HSA-5688426 1.303114e-03 2.885 0 0
HDACs deacetylate histones R-HSA-3214815 1.394734e-03 2.856 0 0
Defective pyroptosis R-HSA-9710421 1.424338e-03 2.846 0 0
Signaling by FGFR4 R-HSA-5654743 1.424338e-03 2.846 0 0
Striated Muscle Contraction R-HSA-390522 1.516307e-03 2.819 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.516307e-03 2.819 0 0
Signaling by FGFR1 R-HSA-5654736 1.550995e-03 2.809 0 0
Regulation of BACH1 activity R-HSA-9708530 1.562532e-03 2.806 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.682523e-03 2.774 0 0
Neurodegenerative Diseases R-HSA-8863678 1.682523e-03 2.774 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.682523e-03 2.774 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.696395e-03 2.770 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.713635e-03 2.766 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.713635e-03 2.766 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 1.740960e-03 2.759 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 1.806016e-03 2.743 0 0
Signaling by FGFR3 R-HSA-5654741 1.806016e-03 2.743 0 0
Muscle contraction R-HSA-397014 1.858165e-03 2.731 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.877979e-03 2.726 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.877979e-03 2.726 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.928995e-03 2.715 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.928995e-03 2.715 0 0
TCR signaling R-HSA-202403 1.955175e-03 2.709 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 1.979745e-03 2.703 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 1.990635e-03 2.701 0 0
Regulation of Apoptosis R-HSA-169911 1.990635e-03 2.701 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.354613e-03 2.628 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.354613e-03 2.628 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 2.691361e-03 2.570 0 0
Packaging Of Telomere Ends R-HSA-171306 2.691361e-03 2.570 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.322224e-03 2.634 0 0
Protein ubiquitination R-HSA-8852135 2.667214e-03 2.574 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.572391e-03 2.590 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 2.198526e-03 2.658 0 0
Chromatin organization R-HSA-4839726 2.151297e-03 2.667 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.267156e-03 2.645 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 2.572391e-03 2.590 0 0
Degradation of DVL R-HSA-4641258 2.572391e-03 2.590 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.077565e-03 2.682 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.572391e-03 2.590 0 0
Signaling by Hippo R-HSA-2028269 2.354613e-03 2.628 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.691361e-03 2.570 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 2.691361e-03 2.570 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.198526e-03 2.658 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.667214e-03 2.574 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.267156e-03 2.645 0 0
Signaling by FGFR R-HSA-190236 2.206698e-03 2.656 0 0
Pexophagy R-HSA-9664873 2.198526e-03 2.658 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.322224e-03 2.634 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.844675e-03 2.546 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 2.901022e-03 2.537 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 3.111758e-03 2.507 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.276704e-03 2.485 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.276704e-03 2.485 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 3.327681e-03 2.478 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 3.404498e-03 2.468 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 3.404498e-03 2.468 0 0
RNA Polymerase I Transcription R-HSA-73864 3.417637e-03 2.466 0 0
Reproduction R-HSA-1474165 3.430386e-03 2.465 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 3.450911e-03 2.462 0 0
Hedgehog ligand biogenesis R-HSA-5358346 3.450911e-03 2.462 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 3.579295e-03 2.446 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 3.579295e-03 2.446 0 0
IRE1alpha activates chaperones R-HSA-381070 3.581505e-03 2.446 0 0
NF-kB is activated and signals survival R-HSA-209560 3.655273e-03 2.437 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 3.679729e-03 2.434 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 3.679729e-03 2.434 0 0
Homology Directed Repair R-HSA-5693538 3.783918e-03 2.422 0 0
Orc1 removal from chromatin R-HSA-68949 3.811771e-03 2.419 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.004786e-03 2.397 0 0
Signaling by MET R-HSA-6806834 4.004786e-03 2.397 0 0
Glycogen synthesis R-HSA-3322077 4.039395e-03 2.394 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 4.119350e-03 2.385 0 0
Gene Silencing by RNA R-HSA-211000 4.406227e-03 2.356 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 4.583150e-03 2.339 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 4.583150e-03 2.339 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 4.583150e-03 2.339 0 0
IRAK1 recruits IKK complex R-HSA-937039 4.583150e-03 2.339 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 4.583150e-03 2.339 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.583150e-03 2.339 0 0
Degradation of CRY and PER proteins R-HSA-9932298 4.597617e-03 2.337 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.597617e-03 2.337 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 4.597617e-03 2.337 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 4.597617e-03 2.337 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.606996e-03 2.337 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.606996e-03 2.337 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.606996e-03 2.337 0 0
Budding and maturation of HIV virion R-HSA-162588 4.668235e-03 2.331 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 4.668235e-03 2.331 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 4.754651e-03 2.323 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 4.754651e-03 2.323 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 5.295907e-03 2.276 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 5.407456e-03 2.267 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 5.416371e-03 2.266 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 5.555495e-03 2.255 0 0
Assembly Of The HIV Virion R-HSA-175474 5.555495e-03 2.255 0 0
DNA Double-Strand Break Repair R-HSA-5693532 5.589508e-03 2.253 0 0
Manipulation of host energy metabolism R-HSA-9636667 6.978764e-03 2.156 0 0
Disinhibition of SNARE formation R-HSA-114516 8.472702e-03 2.072 0 0
SOS-mediated signalling R-HSA-112412 8.472702e-03 2.072 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 8.472702e-03 2.072 0 0
Erythropoietin activates RAS R-HSA-9027284 8.283468e-03 2.082 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 8.283468e-03 2.082 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 7.549387e-03 2.122 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 6.693667e-03 2.174 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 6.285080e-03 2.202 0 0
Regulation of endogenous retroelements R-HSA-9842860 8.008530e-03 2.096 0 0
Translesion synthesis by REV1 R-HSA-110312 8.283468e-03 2.082 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 6.733359e-03 2.172 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 5.657570e-03 2.247 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 7.198934e-03 2.143 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 5.881421e-03 2.231 0 0
Breakdown of the nuclear lamina R-HSA-352238 6.978764e-03 2.156 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 8.434409e-03 2.074 0 0
Signaling by SCF-KIT R-HSA-1433557 5.678388e-03 2.246 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 6.888037e-03 2.162 0 0
Regulation of mitotic cell cycle R-HSA-453276 6.067837e-03 2.217 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 6.067837e-03 2.217 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 5.678388e-03 2.246 0 0
Protein methylation R-HSA-8876725 8.283468e-03 2.082 0 0
ER-Phagosome pathway R-HSA-1236974 8.231905e-03 2.084 0 0
Regulation of necroptotic cell death R-HSA-5675482 5.983237e-03 2.223 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 5.657570e-03 2.247 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 7.549387e-03 2.122 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 5.983237e-03 2.223 0 0
NRIF signals cell death from the nucleus R-HSA-205043 6.888037e-03 2.162 0 0
Nef and signal transduction R-HSA-164944 6.364998e-03 2.196 0 0
Vpu mediated degradation of CD4 R-HSA-180534 6.733359e-03 2.172 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 7.549387e-03 2.122 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 7.549387e-03 2.122 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 8.283468e-03 2.082 0 0
Cyclin D associated events in G1 R-HSA-69231 6.285080e-03 2.202 0 0
G1 Phase R-HSA-69236 6.285080e-03 2.202 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 8.395662e-03 2.076 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 5.983237e-03 2.223 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 5.678388e-03 2.246 0 0
Syndecan interactions R-HSA-3000170 7.434426e-03 2.129 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 6.888037e-03 2.162 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 6.938784e-03 2.159 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 6.938784e-03 2.159 0 0
Pyruvate metabolism R-HSA-70268 7.191108e-03 2.143 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 6.285080e-03 2.202 0 0
Interferon alpha/beta signaling R-HSA-909733 8.091378e-03 2.092 0 0
Unfolded Protein Response (UPR) R-HSA-381119 6.023081e-03 2.220 0 0
XBP1(S) activates chaperone genes R-HSA-381038 6.710465e-03 2.173 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 6.796704e-03 2.168 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 7.549387e-03 2.122 0 0
MAP kinase activation R-HSA-450294 8.517800e-03 2.070 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 8.522469e-03 2.069 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 9.203044e-03 2.036 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.230259e-03 2.035 0 0
Intracellular signaling by second messengers R-HSA-9006925 9.274015e-03 2.033 0 0
Calmodulin induced events R-HSA-111933 9.391474e-03 2.027 0 0
CaM pathway R-HSA-111997 9.391474e-03 2.027 0 0
Translesion synthesis by POLI R-HSA-5656121 9.852160e-03 2.006 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 9.852160e-03 2.006 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 9.986221e-03 2.001 0 0
DNA Damage Bypass R-HSA-73893 1.006584e-02 1.997 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.006584e-02 1.997 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.006584e-02 1.997 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.017805e-02 1.992 0 0
Degradation of AXIN R-HSA-4641257 1.042358e-02 1.982 0 0
Cleavage of the damaged purine R-HSA-110331 1.042358e-02 1.982 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.042358e-02 1.982 0 0
Type I hemidesmosome assembly R-HSA-446107 1.094409e-02 1.961 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.094409e-02 1.961 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.094409e-02 1.961 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.094409e-02 1.961 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.094409e-02 1.961 0 0
Suppression of phagosomal maturation R-HSA-9637687 1.101953e-02 1.958 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.125389e-02 1.949 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.153368e-02 1.938 0 0
Depurination R-HSA-73927 1.153368e-02 1.938 0 0
Translesion synthesis by POLK R-HSA-5655862 1.160176e-02 1.935 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.160176e-02 1.935 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.160176e-02 1.935 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.160176e-02 1.935 0 0
Cellular response to hypoxia R-HSA-1234174 1.163475e-02 1.934 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.184185e-02 1.927 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.196594e-02 1.922 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.207670e-02 1.918 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.207670e-02 1.918 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.207670e-02 1.918 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.207670e-02 1.918 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.207670e-02 1.918 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.207670e-02 1.918 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.208184e-02 1.918 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.243757e-02 1.905 0 0
Stabilization of p53 R-HSA-69541 1.272464e-02 1.895 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.277318e-02 1.894 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.280616e-02 1.893 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.300730e-02 1.886 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.300730e-02 1.886 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.300730e-02 1.886 0 0
Death Receptor Signaling R-HSA-73887 1.321752e-02 1.879 0 0
G-protein mediated events R-HSA-112040 1.347548e-02 1.870 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.349414e-02 1.870 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.349414e-02 1.870 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.353923e-02 1.868 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 1.353923e-02 1.868 0 0
Glycogen storage diseases R-HSA-3229121 1.353923e-02 1.868 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.357847e-02 1.867 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.378966e-02 1.860 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.397430e-02 1.855 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 1.399928e-02 1.854 0 0
Glycogen metabolism R-HSA-8982491 1.399928e-02 1.854 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.411222e-02 1.850 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 1.411222e-02 1.850 0 0
Regulated Necrosis R-HSA-5218859 1.447166e-02 1.839 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.455338e-02 1.837 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.455338e-02 1.837 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.455338e-02 1.837 0 0
Developmental Cell Lineages R-HSA-9734767 1.492994e-02 1.826 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.514040e-02 1.820 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 1.528263e-02 1.816 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.536032e-02 1.814 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 1.536032e-02 1.814 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 1.536032e-02 1.814 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 1.563373e-02 1.806 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 1.567087e-02 1.805 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.577804e-02 1.802 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.584244e-02 1.800 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.584244e-02 1.800 0 0
DNA Repair R-HSA-73894 1.595110e-02 1.797 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.606904e-02 1.794 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.615892e-02 1.792 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.615892e-02 1.792 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.615892e-02 1.792 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 1.652046e-02 1.782 0 0
G alpha (z) signalling events R-HSA-418597 1.652046e-02 1.782 0 0
Signaling by NOTCH3 R-HSA-9012852 1.652046e-02 1.782 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.662296e-02 1.779 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.662296e-02 1.779 0 0
Interleukin-17 signaling R-HSA-448424 1.662296e-02 1.779 0 0
Regulation of CDH11 function R-HSA-9762292 1.701676e-02 1.769 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.701676e-02 1.769 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 1.713232e-02 1.766 0 0
DAP12 signaling R-HSA-2424491 1.741964e-02 1.759 0 0
Hedgehog 'on' state R-HSA-5632684 1.778095e-02 1.750 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 1.782757e-02 1.749 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 1.782757e-02 1.749 0 0
TNF signaling R-HSA-75893 1.782757e-02 1.749 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 1.782757e-02 1.749 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 1.800226e-02 1.745 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.835203e-02 1.736 0 0
MTOR signalling R-HSA-165159 1.835203e-02 1.736 0 0
Ca-dependent events R-HSA-111996 1.835203e-02 1.736 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.835203e-02 1.736 0 0
Depyrimidination R-HSA-73928 1.835203e-02 1.736 0 0
FasL/ CD95L signaling R-HSA-75157 1.836966e-02 1.736 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 1.848464e-02 1.733 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 1.848464e-02 1.733 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.899570e-02 1.721 0 0
Interleukin-1 signaling R-HSA-9020702 1.907120e-02 1.720 0 0
Trafficking of AMPA receptors R-HSA-399719 1.933558e-02 1.714 0 0
Switching of origins to a post-replicative state R-HSA-69052 2.026858e-02 1.693 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.026858e-02 1.693 0 0
Signal transduction by L1 R-HSA-445144 2.053831e-02 1.687 0 0
Circadian clock R-HSA-9909396 2.129670e-02 1.672 0 0
Opioid Signalling R-HSA-111885 2.235120e-02 1.651 0 0
Downstream TCR signaling R-HSA-202424 2.293982e-02 1.639 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.328320e-02 1.633 0 0
Basigin interactions R-HSA-210991 2.328320e-02 1.633 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.328320e-02 1.633 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 2.328320e-02 1.633 0 0
Activation of HOX genes during differentiation R-HSA-5619507 2.353029e-02 1.628 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 2.353029e-02 1.628 0 0
DAG and IP3 signaling R-HSA-1489509 2.355024e-02 1.628 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 2.355024e-02 1.628 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 2.355024e-02 1.628 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 2.357049e-02 1.628 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 2.357049e-02 1.628 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 2.359567e-02 1.627 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 2.359567e-02 1.627 0 0
Nucleotide Excision Repair R-HSA-5696398 2.475366e-02 1.606 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 2.484480e-02 1.605 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 2.546427e-02 1.594 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 2.548144e-02 1.594 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 2.548144e-02 1.594 0 0
Regulation of TNFR1 signaling R-HSA-5357905 2.548144e-02 1.594 0 0
Regulation of pyruvate metabolism R-HSA-9861718 2.548144e-02 1.594 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.575357e-02 1.589 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.575357e-02 1.589 0 0
MTF1 activates gene expression R-HSA-5660489 2.575357e-02 1.589 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.624046e-02 1.581 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.624046e-02 1.581 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 2.624046e-02 1.581 0 0
Protein localization R-HSA-9609507 2.680424e-02 1.572 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 2.711817e-02 1.567 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 2.711817e-02 1.567 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 2.733648e-02 1.563 0 0
Signaling by ALK in cancer R-HSA-9700206 2.733648e-02 1.563 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 2.751528e-02 1.560 0 0
ABC transporter disorders R-HSA-5619084 2.755060e-02 1.560 0 0
Dual Incision in GG-NER R-HSA-5696400 2.836177e-02 1.547 0 0
Mitophagy R-HSA-5205647 2.836177e-02 1.547 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.836177e-02 1.547 0 0
Antigen processing-Cross presentation R-HSA-1236975 2.869752e-02 1.542 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.901971e-02 1.537 0 0
GRB2 events in EGFR signaling R-HSA-179812 2.901971e-02 1.537 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 2.906337e-02 1.537 0 0
HIV Infection R-HSA-162906 2.912514e-02 1.536 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 2.941291e-02 1.531 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 2.941291e-02 1.531 0 0
Signalling to ERKs R-HSA-187687 3.097218e-02 1.509 0 0
Oncogene Induced Senescence R-HSA-2559585 3.097218e-02 1.509 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 3.098555e-02 1.509 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 3.138313e-02 1.503 0 0
Parasite infection R-HSA-9664407 3.138313e-02 1.503 0 0
Leishmania phagocytosis R-HSA-9664417 3.138313e-02 1.503 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.189809e-02 1.496 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 4.021841e-02 1.396 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 3.413078e-02 1.467 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.413078e-02 1.467 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.350443e-02 1.272 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.350443e-02 1.272 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 5.350443e-02 1.272 0 0
SHC1 events in EGFR signaling R-HSA-180336 4.447814e-02 1.352 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 5.037559e-02 1.298 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 5.037559e-02 1.298 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 6.323800e-02 1.199 0 0
Deadenylation of mRNA R-HSA-429947 3.641147e-02 1.439 0 0
Tight junction interactions R-HSA-420029 4.024001e-02 1.395 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 4.855710e-02 1.314 0 0
Signaling by Erythropoietin R-HSA-9006335 5.774955e-02 1.238 0 0
mRNA 3'-end processing R-HSA-72187 3.928383e-02 1.406 0 0
Dual incision in TC-NER R-HSA-6782135 5.709169e-02 1.243 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 3.454950e-02 1.462 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 5.217525e-02 1.283 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 5.787401e-02 1.238 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 3.413078e-02 1.467 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 5.663211e-02 1.247 0 0
Peroxisomal protein import R-HSA-9033241 6.046180e-02 1.219 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.834929e-02 1.316 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.340968e-02 1.362 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 4.447814e-02 1.352 0 0
Termination of translesion DNA synthesis R-HSA-5656169 5.774955e-02 1.238 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 6.394770e-02 1.194 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 6.394770e-02 1.194 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 6.394770e-02 1.194 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 6.394770e-02 1.194 0 0
p38MAPK events R-HSA-171007 4.447814e-02 1.352 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 6.046180e-02 1.219 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 4.406850e-02 1.356 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 3.413078e-02 1.467 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 4.451457e-02 1.351 0 0
Regulation of KIT signaling R-HSA-1433559 3.894836e-02 1.410 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 6.394770e-02 1.194 0 0
Cellular response to chemical stress R-HSA-9711123 5.473937e-02 1.262 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.196751e-02 1.377 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 5.663211e-02 1.247 0 0
Pentose phosphate pathway R-HSA-71336 4.288879e-02 1.368 0 0
Malate-aspartate shuttle R-HSA-9856872 3.894836e-02 1.410 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 5.774955e-02 1.238 0 0
Telomere Maintenance R-HSA-157579 3.671666e-02 1.435 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.024001e-02 1.395 0 0
Base Excision Repair R-HSA-73884 5.445750e-02 1.264 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.495873e-02 1.456 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.350443e-02 1.272 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.671666e-02 1.435 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.280274e-02 1.484 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.428865e-02 1.354 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 5.069807e-02 1.295 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 4.855710e-02 1.314 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.041189e-02 1.393 0 0
Interleukin-7 signaling R-HSA-1266695 4.024001e-02 1.395 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.855710e-02 1.314 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 5.787401e-02 1.238 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 4.476388e-02 1.349 0 0
Translation of Structural Proteins R-HSA-9683701 5.340766e-02 1.272 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.433460e-02 1.192 0 0
CHL1 interactions R-HSA-447041 6.433460e-02 1.192 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.433460e-02 1.192 0 0
PIP3 activates AKT signaling R-HSA-1257604 6.517059e-02 1.186 0 0
DAP12 interactions R-HSA-2172127 6.529510e-02 1.185 0 0
G1/S Transition R-HSA-69206 6.673901e-02 1.176 0 0
Formation of paraxial mesoderm R-HSA-9793380 6.754941e-02 1.170 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 6.754941e-02 1.170 0 0
PLC beta mediated events R-HSA-112043 6.754941e-02 1.170 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 6.780438e-02 1.169 0 0
Nucleosome assembly R-HSA-774815 6.956044e-02 1.158 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 6.956044e-02 1.158 0 0
Somitogenesis R-HSA-9824272 6.956044e-02 1.158 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 6.969506e-02 1.157 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.314902e-02 1.136 0 0
Formation of annular gap junctions R-HSA-196025 7.582492e-02 1.120 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 7.582492e-02 1.120 0 0
Activation of RAS in B cells R-HSA-1169092 7.582492e-02 1.120 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 7.582492e-02 1.120 0 0
Rap1 signalling R-HSA-392517 7.745452e-02 1.111 0 0
Integrin signaling R-HSA-354192 7.870096e-02 1.104 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 7.870096e-02 1.104 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 7.882164e-02 1.103 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 7.882164e-02 1.103 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 7.882164e-02 1.103 0 0
Hereditary fructose intolerance R-HSA-5657560 7.882164e-02 1.103 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 7.882164e-02 1.103 0 0
TICAM1 deficiency - HSE R-HSA-5602566 7.882164e-02 1.103 0 0
Inhibition of PKR R-HSA-169131 7.882164e-02 1.103 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 7.953687e-02 1.099 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 8.050273e-02 1.094 0 0
Co-stimulation by CD28 R-HSA-389356 8.325277e-02 1.080 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 8.504154e-02 1.070 0 0
Lipophagy R-HSA-9613354 8.790493e-02 1.056 0 0
Gap junction degradation R-HSA-190873 8.790493e-02 1.056 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 8.790493e-02 1.056 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 8.790493e-02 1.056 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 8.790493e-02 1.056 0 0
ARMS-mediated activation R-HSA-170984 8.790493e-02 1.056 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 8.790493e-02 1.056 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 8.790493e-02 1.056 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 8.790493e-02 1.056 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 8.811123e-02 1.055 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.041182e-02 1.044 0 0
Signaling by NOTCH2 R-HSA-1980145 9.041182e-02 1.044 0 0
ABC-family proteins mediated transport R-HSA-382556 9.058250e-02 1.043 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 9.293097e-02 1.032 0 0
Signalling to RAS R-HSA-167044 9.293097e-02 1.032 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 9.293097e-02 1.032 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 9.597618e-02 1.018 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 9.656238e-02 1.015 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 9.797550e-02 1.009 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 9.986073e-02 1.001 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.004885e-01 0.998 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 1.005088e-01 0.998 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.005088e-01 0.998 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 1.013526e-01 0.994 0 0
GPVI-mediated activation cascade R-HSA-114604 1.029036e-01 0.988 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.042928e-01 0.982 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.051019e-01 0.978 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 1.051019e-01 0.978 0 0
Chromosome Maintenance R-HSA-73886 1.083042e-01 0.965 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 1.083042e-01 0.965 0 0
RSV-host interactions R-HSA-9833110 1.089223e-01 0.963 0 0
FGFR2 alternative splicing R-HSA-6803529 1.095640e-01 0.960 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 1.095640e-01 0.960 0 0
Signaling by KIT in disease R-HSA-9669938 1.095640e-01 0.960 0 0
PTEN Regulation R-HSA-6807070 1.134469e-01 0.945 0 0
Suppression of apoptosis R-HSA-9635465 1.135750e-01 0.945 0 0
PECAM1 interactions R-HSA-210990 1.135750e-01 0.945 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.135750e-01 0.945 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.135750e-01 0.945 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.146796e-01 0.941 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 1.158745e-01 0.936 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 1.158745e-01 0.936 0 0
TRAF3 deficiency - HSE R-HSA-5602571 1.158745e-01 0.936 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 1.158745e-01 0.936 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.158745e-01 0.936 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 1.158745e-01 0.936 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.158745e-01 0.936 0 0
Ca2+ pathway R-HSA-4086398 1.196234e-01 0.922 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 1.196234e-01 0.922 0 0
Parasitic Infection Pathways R-HSA-9824443 1.196456e-01 0.922 0 0
Leishmania infection R-HSA-9658195 1.196456e-01 0.922 0 0
Signaling by TGFB family members R-HSA-9006936 1.205009e-01 0.919 0 0
Synthesis of DNA R-HSA-69239 1.208322e-01 0.918 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.230201e-01 0.910 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.230201e-01 0.910 0 0
Plasma lipoprotein clearance R-HSA-8964043 1.230201e-01 0.910 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.260425e-01 0.899 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.270460e-01 0.896 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.270460e-01 0.896 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.270460e-01 0.896 0 0
Activation of RAC1 R-HSA-428540 1.270460e-01 0.896 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.270460e-01 0.896 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.270460e-01 0.896 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.272443e-01 0.895 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.274318e-01 0.895 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.300717e-01 0.886 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.319918e-01 0.879 0 0
Signaling by NOTCH1 R-HSA-1980143 1.350728e-01 0.869 0 0
HDMs demethylate histones R-HSA-3214842 1.364421e-01 0.865 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.386849e-01 0.858 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.398811e-01 0.854 0 0
Mitochondrial protein degradation R-HSA-9837999 1.398811e-01 0.854 0 0
Translation of Structural Proteins R-HSA-9694635 1.404226e-01 0.853 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.408684e-01 0.851 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.408684e-01 0.851 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 1.408684e-01 0.851 0 0
MET activates RAS signaling R-HSA-8851805 1.408684e-01 0.851 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 1.408684e-01 0.851 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.408684e-01 0.851 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 1.458593e-01 0.836 0 0
Myogenesis R-HSA-525793 1.458593e-01 0.836 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 1.458593e-01 0.836 0 0
S Phase R-HSA-69242 1.500678e-01 0.824 0 0
Signaling by NTRKs R-HSA-166520 1.500678e-01 0.824 0 0
RAB geranylgeranylation R-HSA-8873719 1.505712e-01 0.822 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.511503e-01 0.821 0 0
Sensory processing of sound R-HSA-9659379 1.514106e-01 0.820 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.514391e-01 0.820 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 1.514391e-01 0.820 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 1.514391e-01 0.820 0 0
Activation of GABAB receptors R-HSA-991365 1.521830e-01 0.818 0 0
GABA B receptor activation R-HSA-977444 1.521830e-01 0.818 0 0
Asparagine N-linked glycosylation R-HSA-446203 1.523293e-01 0.817 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.549922e-01 0.810 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.549922e-01 0.810 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 1.549922e-01 0.810 0 0
Frs2-mediated activation R-HSA-170968 1.549922e-01 0.810 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.549922e-01 0.810 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.549922e-01 0.810 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 1.549922e-01 0.810 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.549922e-01 0.810 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 1.554818e-01 0.808 0 0
Toll-like Receptor Cascades R-HSA-168898 1.603823e-01 0.795 0 0
Mitochondrial protein import R-HSA-1268020 1.635335e-01 0.786 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 1.652955e-01 0.782 0 0
Interleukin-1 family signaling R-HSA-446652 1.662168e-01 0.779 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.693708e-01 0.771 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.693708e-01 0.771 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.693708e-01 0.771 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 1.744799e-01 0.758 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 1.752862e-01 0.756 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.755976e-01 0.755 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.755976e-01 0.755 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.809794e-01 0.742 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 1.836620e-01 0.736 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 1.839610e-01 0.735 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.839610e-01 0.735 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.839610e-01 0.735 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.839610e-01 0.735 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.839610e-01 0.735 0 0
Classical Kir channels R-HSA-1296053 1.855752e-01 0.731 0 0
MET interacts with TNS proteins R-HSA-8875513 1.855752e-01 0.731 0 0
HIV Life Cycle R-HSA-162587 1.875221e-01 0.727 0 0
HCMV Late Events R-HSA-9610379 1.875221e-01 0.727 0 0
Downstream signal transduction R-HSA-186763 1.957432e-01 0.708 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 1.987227e-01 0.702 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 1.987227e-01 0.702 0 0
Prolonged ERK activation events R-HSA-169893 1.987227e-01 0.702 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.987227e-01 0.702 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 1.987227e-01 0.702 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 1.987227e-01 0.702 0 0
GPER1 signaling R-HSA-9634597 2.001404e-01 0.699 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.001404e-01 0.699 0 0
Regulation of TP53 Activity R-HSA-5633007 2.008663e-01 0.697 0 0
Extracellular matrix organization R-HSA-1474244 2.008964e-01 0.697 0 0
Post-translational protein modification R-HSA-597592 2.012022e-01 0.696 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 2.052737e-01 0.688 0 0
G0 and Early G1 R-HSA-1538133 2.061824e-01 0.686 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 2.136185e-01 0.670 0 0
Response to metal ions R-HSA-5660526 2.136185e-01 0.670 0 0
Nuclear RNA decay R-HSA-9930044 2.167441e-01 0.664 0 0
HCN channels R-HSA-1296061 2.183400e-01 0.661 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.183400e-01 0.661 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.183400e-01 0.661 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.183400e-01 0.661 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 2.183400e-01 0.661 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 2.183400e-01 0.661 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.183400e-01 0.661 0 0
NADE modulates death signalling R-HSA-205025 2.183400e-01 0.661 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.183400e-01 0.661 0 0
FCERI mediated NF-kB activation R-HSA-2871837 2.256852e-01 0.646 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 2.274155e-01 0.643 0 0
Glutamate and glutamine metabolism R-HSA-8964539 2.274155e-01 0.643 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 2.341485e-01 0.631 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 2.343093e-01 0.630 0 0
Signal amplification R-HSA-392518 2.381838e-01 0.623 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 2.381838e-01 0.623 0 0
GAB1 signalosome R-HSA-180292 2.436765e-01 0.613 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.436765e-01 0.613 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.436765e-01 0.613 0 0
Tie2 Signaling R-HSA-210993 2.436765e-01 0.613 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 2.443018e-01 0.612 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 2.487885e-01 0.604 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 2.490366e-01 0.604 0 0
PERK regulates gene expression R-HSA-381042 2.490366e-01 0.604 0 0
IRS activation R-HSA-74713 2.497886e-01 0.602 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.497886e-01 0.602 0 0
G2 Phase R-HSA-68911 2.497886e-01 0.602 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 2.497886e-01 0.602 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.497886e-01 0.602 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.497886e-01 0.602 0 0
Suppression of autophagy R-HSA-9636569 2.497886e-01 0.602 0 0
NTRK2 activates RAC1 R-HSA-9032759 2.497886e-01 0.602 0 0
Muscarinic acetylcholine receptors R-HSA-390648 2.497886e-01 0.602 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.497886e-01 0.602 0 0
FCERI mediated MAPK activation R-HSA-2871796 2.505640e-01 0.601 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.587771e-01 0.587 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.587771e-01 0.587 0 0
The NLRP3 inflammasome R-HSA-844456 2.587771e-01 0.587 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.587771e-01 0.587 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 2.599618e-01 0.585 0 0
RET signaling R-HSA-8853659 2.599618e-01 0.585 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 2.722432e-01 0.565 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.738882e-01 0.562 0 0
Protein hydroxylation R-HSA-9629569 2.738882e-01 0.562 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.738882e-01 0.562 0 0
Plus-strand DNA synthesis R-HSA-164525 2.799738e-01 0.553 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.799738e-01 0.553 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.799738e-01 0.553 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.799738e-01 0.553 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.799738e-01 0.553 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.799738e-01 0.553 0 0
Pentose phosphate pathway disease R-HSA-6791465 2.799738e-01 0.553 0 0
Phosphorylation of Emi1 R-HSA-176417 2.799738e-01 0.553 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.799738e-01 0.553 0 0
TRAIL signaling R-HSA-75158 2.799738e-01 0.553 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.799738e-01 0.553 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 2.889845e-01 0.539 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 2.889845e-01 0.539 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 2.889845e-01 0.539 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 2.930569e-01 0.533 0 0
Mitochondrial biogenesis R-HSA-1592230 2.944094e-01 0.531 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.957006e-01 0.529 0 0
FOXO-mediated transcription R-HSA-9614085 2.994013e-01 0.524 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 3.035959e-01 0.518 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 3.040429e-01 0.517 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 3.040429e-01 0.517 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 3.040429e-01 0.517 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.040429e-01 0.517 0 0
Ribavirin ADME R-HSA-9755088 3.040429e-01 0.517 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.040429e-01 0.517 0 0
Generation of second messenger molecules R-HSA-202433 3.041584e-01 0.517 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 3.041584e-01 0.517 0 0
Diseases of Immune System R-HSA-5260271 3.041584e-01 0.517 0 0
GABA receptor activation R-HSA-977443 3.060247e-01 0.514 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 3.089462e-01 0.510 0 0
Signaling by LTK in cancer R-HSA-9842640 3.089462e-01 0.510 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.089462e-01 0.510 0 0
Uncoating of the HIV Virion R-HSA-162585 3.089462e-01 0.510 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 3.089462e-01 0.510 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.089462e-01 0.510 0 0
CREB phosphorylation R-HSA-199920 3.089462e-01 0.510 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.089462e-01 0.510 0 0
VLDL assembly R-HSA-8866423 3.089462e-01 0.510 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 3.172703e-01 0.499 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 3.190419e-01 0.496 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 3.190419e-01 0.496 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.339620e-01 0.476 0 0
Growth hormone receptor signaling R-HSA-982772 3.339620e-01 0.476 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.367545e-01 0.473 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 3.367545e-01 0.473 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 3.367545e-01 0.473 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.367545e-01 0.473 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.367545e-01 0.473 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.367545e-01 0.473 0 0
Recycling of eIF2:GDP R-HSA-72731 3.367545e-01 0.473 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.367545e-01 0.473 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.367545e-01 0.473 0 0
LDL remodeling R-HSA-8964041 3.367545e-01 0.473 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.367545e-01 0.473 0 0
Formation of the cornified envelope R-HSA-6809371 3.397752e-01 0.469 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 3.434677e-01 0.464 0 0
Amplification of signal from the kinetochores R-HSA-141424 3.434677e-01 0.464 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 3.434677e-01 0.464 0 0
TBC/RABGAPs R-HSA-8854214 3.486426e-01 0.458 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 3.487854e-01 0.457 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 3.487854e-01 0.457 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 3.487854e-01 0.457 0 0
Proteasome assembly R-HSA-9907900 3.597366e-01 0.444 0 0
Reverse Transcription of HIV RNA R-HSA-162589 3.634454e-01 0.440 0 0
Minus-strand DNA synthesis R-HSA-164516 3.634454e-01 0.440 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.634454e-01 0.440 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 3.634454e-01 0.440 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 3.634454e-01 0.440 0 0
Regulation by c-FLIP R-HSA-3371378 3.634454e-01 0.440 0 0
FGFR1b ligand binding and activation R-HSA-190370 3.634454e-01 0.440 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.634454e-01 0.440 0 0
Dimerization of procaspase-8 R-HSA-69416 3.634454e-01 0.440 0 0
Sodium/Proton exchangers R-HSA-425986 3.634454e-01 0.440 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 3.634454e-01 0.440 0 0
Interleukin-23 signaling R-HSA-9020933 3.634454e-01 0.440 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 3.634957e-01 0.440 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 3.634957e-01 0.440 0 0
G protein gated Potassium channels R-HSA-1296059 3.634957e-01 0.440 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 3.634957e-01 0.440 0 0
Laminin interactions R-HSA-3000157 3.634957e-01 0.440 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.634957e-01 0.440 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.634957e-01 0.440 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 3.634957e-01 0.440 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 3.634957e-01 0.440 0 0
Gene expression (Transcription) R-HSA-74160 3.647846e-01 0.438 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.677516e-01 0.434 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 3.704168e-01 0.431 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 3.708027e-01 0.431 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 3.780779e-01 0.422 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.780779e-01 0.422 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 3.780779e-01 0.422 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.818327e-01 0.418 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 3.818327e-01 0.418 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.890637e-01 0.410 0 0
CASP8 activity is inhibited R-HSA-5218900 3.890637e-01 0.410 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.890637e-01 0.410 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.890637e-01 0.410 0 0
Calcineurin activates NFAT R-HSA-2025928 3.890637e-01 0.410 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.890637e-01 0.410 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.890637e-01 0.410 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 3.890637e-01 0.410 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.890637e-01 0.410 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.890637e-01 0.410 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 3.890637e-01 0.410 0 0
RNA Polymerase II Transcription R-HSA-73857 3.895914e-01 0.409 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 3.916964e-01 0.407 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 3.925187e-01 0.406 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 3.925187e-01 0.406 0 0
Cristae formation R-HSA-8949613 3.925187e-01 0.406 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 3.925187e-01 0.406 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 3.925187e-01 0.406 0 0
Signaling by FGFR3 in disease R-HSA-5655332 3.925187e-01 0.406 0 0
HIV elongation arrest and recovery R-HSA-167287 4.068058e-01 0.391 0 0
Pausing and recovery of HIV elongation R-HSA-167290 4.068058e-01 0.391 0 0
Telomere Extension By Telomerase R-HSA-171319 4.068058e-01 0.391 0 0
Inflammasomes R-HSA-622312 4.068058e-01 0.391 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 4.068058e-01 0.391 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 4.068058e-01 0.391 0 0
Pyroptosis R-HSA-5620971 4.068058e-01 0.391 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 4.077446e-01 0.390 0 0
Binding and entry of HIV virion R-HSA-173107 4.136526e-01 0.383 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 4.136526e-01 0.383 0 0
PI3K/AKT activation R-HSA-198203 4.136526e-01 0.383 0 0
Signal attenuation R-HSA-74749 4.136526e-01 0.383 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 4.136526e-01 0.383 0 0
MAPK3 (ERK1) activation R-HSA-110056 4.136526e-01 0.383 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 4.136526e-01 0.383 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 4.136526e-01 0.383 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 4.136526e-01 0.383 0 0
Signaling by Leptin R-HSA-2586552 4.136526e-01 0.383 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 4.162499e-01 0.381 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 4.209282e-01 0.376 0 0
Collagen formation R-HSA-1474290 4.237358e-01 0.373 0 0
Azathioprine ADME R-HSA-9748787 4.254466e-01 0.371 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 4.348761e-01 0.362 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 4.348761e-01 0.362 0 0
The phototransduction cascade R-HSA-2514856 4.361900e-01 0.360 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 4.372532e-01 0.359 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.372532e-01 0.359 0 0
vRNP Assembly R-HSA-192905 4.372532e-01 0.359 0 0
Chylomicron assembly R-HSA-8963888 4.372532e-01 0.359 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 4.372532e-01 0.359 0 0
Bicarbonate transporters R-HSA-425381 4.372532e-01 0.359 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 4.372532e-01 0.359 0 0
Interleukin-2 signaling R-HSA-9020558 4.372532e-01 0.359 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.372532e-01 0.359 0 0
Integration of energy metabolism R-HSA-163685 4.388502e-01 0.358 0 0
Iron uptake and transport R-HSA-917937 4.434033e-01 0.353 0 0
Generic Transcription Pathway R-HSA-212436 4.446161e-01 0.352 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.468574e-01 0.350 0 0
Potassium Channels R-HSA-1296071 4.475636e-01 0.349 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 4.486406e-01 0.348 0 0
Molecules associated with elastic fibres R-HSA-2129379 4.486406e-01 0.348 0 0
Rab regulation of trafficking R-HSA-9007101 4.502116e-01 0.347 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.574431e-01 0.340 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.574431e-01 0.340 0 0
Signaling by GSK3beta mutants R-HSA-5339716 4.599053e-01 0.337 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.599053e-01 0.337 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 4.599053e-01 0.337 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.599053e-01 0.337 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.599053e-01 0.337 0 0
Plasmalogen biosynthesis R-HSA-75896 4.599053e-01 0.337 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 4.599053e-01 0.337 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 4.599053e-01 0.337 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 4.599053e-01 0.337 0 0
Integration of provirus R-HSA-162592 4.599053e-01 0.337 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.599053e-01 0.337 0 0
Diseases of mitotic cell cycle R-HSA-9675126 4.622139e-01 0.335 0 0
Inwardly rectifying K+ channels R-HSA-1296065 4.622139e-01 0.335 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 4.622139e-01 0.335 0 0
Post-translational protein phosphorylation R-HSA-8957275 4.633102e-01 0.334 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 4.755891e-01 0.323 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 4.755891e-01 0.323 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.755891e-01 0.323 0 0
Mitotic Spindle Checkpoint R-HSA-69618 4.789214e-01 0.320 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 4.789800e-01 0.320 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 4.816469e-01 0.317 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.816469e-01 0.317 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 4.816469e-01 0.317 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 4.816469e-01 0.317 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 4.816469e-01 0.317 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 4.816469e-01 0.317 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.816469e-01 0.317 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 4.816469e-01 0.317 0 0
Acetylation R-HSA-156582 4.816469e-01 0.317 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 4.816469e-01 0.317 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 4.816469e-01 0.317 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.816469e-01 0.317 0 0
OAS antiviral response R-HSA-8983711 4.816469e-01 0.317 0 0
NRAGE signals death through JNK R-HSA-193648 4.886608e-01 0.311 0 0
Ion homeostasis R-HSA-5578775 4.886608e-01 0.311 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 4.887602e-01 0.311 0 0
Effects of PIP2 hydrolysis R-HSA-114508 4.887602e-01 0.311 0 0
IRS-mediated signalling R-HSA-112399 4.988718e-01 0.302 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 5.017220e-01 0.300 0 0
Nuclear import of Rev protein R-HSA-180746 5.017220e-01 0.300 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 5.017220e-01 0.300 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 5.025145e-01 0.299 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 5.025145e-01 0.299 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 5.025145e-01 0.299 0 0
FGFR1c ligand binding and activation R-HSA-190373 5.025145e-01 0.299 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 5.025145e-01 0.299 0 0
Formation of axial mesoderm R-HSA-9796292 5.025145e-01 0.299 0 0
Maturation of nucleoprotein R-HSA-9683610 5.025145e-01 0.299 0 0
Interleukin-6 signaling R-HSA-1059683 5.025145e-01 0.299 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.025145e-01 0.299 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 5.089786e-01 0.293 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 5.089786e-01 0.293 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 5.144699e-01 0.289 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 5.144699e-01 0.289 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 5.144699e-01 0.289 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 5.189776e-01 0.285 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 5.225433e-01 0.282 0 0
CRMPs in Sema3A signaling R-HSA-399956 5.225433e-01 0.282 0 0
Prolactin receptor signaling R-HSA-1170546 5.225433e-01 0.282 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 5.225433e-01 0.282 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 5.225433e-01 0.282 0 0
Zinc transporters R-HSA-435354 5.225433e-01 0.282 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.225433e-01 0.282 0 0
G1/S-Specific Transcription R-HSA-69205 5.270002e-01 0.278 0 0
Regulation of PTEN gene transcription R-HSA-8943724 5.288655e-01 0.277 0 0
Disorders of transmembrane transporters R-HSA-5619115 5.362760e-01 0.271 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.386391e-01 0.269 0 0
Voltage gated Potassium channels R-HSA-1296072 5.393097e-01 0.268 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 5.417669e-01 0.266 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.417669e-01 0.266 0 0
G beta:gamma signalling through BTK R-HSA-8964315 5.417669e-01 0.266 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.417669e-01 0.266 0 0
DCC mediated attractive signaling R-HSA-418885 5.417669e-01 0.266 0 0
Other semaphorin interactions R-HSA-416700 5.417669e-01 0.266 0 0
Stimuli-sensing channels R-HSA-2672351 5.470067e-01 0.262 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 5.472027e-01 0.262 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 5.478124e-01 0.261 0 0
NCAM signaling for neurite out-growth R-HSA-375165 5.482956e-01 0.261 0 0
Signaling by PDGF R-HSA-186797 5.482956e-01 0.261 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 5.513960e-01 0.259 0 0
MET promotes cell motility R-HSA-8875878 5.513960e-01 0.259 0 0
Elastic fibre formation R-HSA-1566948 5.513960e-01 0.259 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 5.578325e-01 0.253 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.602176e-01 0.252 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 5.602176e-01 0.252 0 0
Phosphorylation of the APC/C R-HSA-176412 5.602176e-01 0.252 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.602176e-01 0.252 0 0
Killing mechanisms R-HSA-9664420 5.602176e-01 0.252 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.602176e-01 0.252 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.602176e-01 0.252 0 0
Fructose catabolism R-HSA-70350 5.602176e-01 0.252 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.602176e-01 0.252 0 0
Activation of SMO R-HSA-5635838 5.602176e-01 0.252 0 0
Attachment and Entry R-HSA-9678110 5.602176e-01 0.252 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 5.632570e-01 0.249 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 5.632570e-01 0.249 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 5.632570e-01 0.249 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 5.632570e-01 0.249 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 5.632570e-01 0.249 0 0
Insulin receptor signalling cascade R-HSA-74751 5.672474e-01 0.246 0 0
IGF1R signaling cascade R-HSA-2428924 5.672474e-01 0.246 0 0
Ion transport by P-type ATPases R-HSA-936837 5.672474e-01 0.246 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.748912e-01 0.240 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 5.748912e-01 0.240 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 5.748912e-01 0.240 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 5.748912e-01 0.240 0 0
HIV Transcription Elongation R-HSA-167169 5.748912e-01 0.240 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 5.765382e-01 0.239 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.779265e-01 0.238 0 0
Fibronectin matrix formation R-HSA-1566977 5.779265e-01 0.238 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 5.779265e-01 0.238 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.779265e-01 0.238 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.779265e-01 0.238 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.779265e-01 0.238 0 0
Galactose catabolism R-HSA-70370 5.779265e-01 0.238 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 5.779265e-01 0.238 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 5.862978e-01 0.232 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 5.918327e-01 0.228 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 5.949234e-01 0.226 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 5.949234e-01 0.226 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 5.949234e-01 0.226 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 5.949234e-01 0.226 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 5.968800e-01 0.224 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 5.974762e-01 0.224 0 0
Signaling by FGFR1 in disease R-HSA-5655302 5.974762e-01 0.224 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 6.036485e-01 0.219 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 6.084262e-01 0.216 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 6.084262e-01 0.216 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 6.084262e-01 0.216 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.112367e-01 0.214 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 6.112367e-01 0.214 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.112367e-01 0.214 0 0
Presynaptic function of Kainate receptors R-HSA-500657 6.112367e-01 0.214 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 6.112367e-01 0.214 0 0
FGFR1 ligand binding and activation R-HSA-190242 6.112367e-01 0.214 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 6.112367e-01 0.214 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 6.112367e-01 0.214 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.112367e-01 0.214 0 0
Ion channel transport R-HSA-983712 6.205954e-01 0.207 0 0
Germ layer formation at gastrulation R-HSA-9754189 6.268941e-01 0.203 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 6.268941e-01 0.203 0 0
Specification of the neural plate border R-HSA-9834899 6.268941e-01 0.203 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 6.268941e-01 0.203 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 6.268941e-01 0.203 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 6.268941e-01 0.203 0 0
Maturation of nucleoprotein R-HSA-9694631 6.268941e-01 0.203 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 6.268941e-01 0.203 0 0
Other interleukin signaling R-HSA-449836 6.268941e-01 0.203 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.268941e-01 0.203 0 0
ECM proteoglycans R-HSA-3000178 6.295869e-01 0.201 0 0
Netrin-1 signaling R-HSA-373752 6.296426e-01 0.201 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 6.399105e-01 0.194 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 6.399105e-01 0.194 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 6.419217e-01 0.193 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 6.419217e-01 0.193 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 6.419217e-01 0.193 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.419217e-01 0.193 0 0
Co-inhibition by CTLA4 R-HSA-389513 6.419217e-01 0.193 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.419217e-01 0.193 0 0
Creatine metabolism R-HSA-71288 6.419217e-01 0.193 0 0
Formation of definitive endoderm R-HSA-9823730 6.419217e-01 0.193 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.419217e-01 0.193 0 0
Signaling by TGFBR3 R-HSA-9839373 6.499530e-01 0.187 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.499530e-01 0.187 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.499530e-01 0.187 0 0
Regulation of insulin secretion R-HSA-422356 6.541946e-01 0.184 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 6.543292e-01 0.184 0 0
G-protein activation R-HSA-202040 6.563450e-01 0.183 0 0
Early Phase of HIV Life Cycle R-HSA-162594 6.563450e-01 0.183 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.563450e-01 0.183 0 0
ERK/MAPK targets R-HSA-198753 6.563450e-01 0.183 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.563450e-01 0.183 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 6.563450e-01 0.183 0 0
Neddylation R-HSA-8951664 6.566042e-01 0.183 0 0
NGF-stimulated transcription R-HSA-9031628 6.693684e-01 0.174 0 0
Metal ion SLC transporters R-HSA-425410 6.693684e-01 0.174 0 0
Serine metabolism R-HSA-977347 6.701882e-01 0.174 0 0
Androgen biosynthesis R-HSA-193048 6.701882e-01 0.174 0 0
Mitochondrial calcium ion transport R-HSA-8949215 6.701882e-01 0.174 0 0
Attachment and Entry R-HSA-9694614 6.701882e-01 0.174 0 0
Leishmania parasite growth and survival R-HSA-9664433 6.733290e-01 0.172 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 6.733290e-01 0.172 0 0
Gastrulation R-HSA-9758941 6.816847e-01 0.166 0 0
Notch-HLH transcription pathway R-HSA-350054 6.834745e-01 0.165 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 6.834745e-01 0.165 0 0
Fructose metabolism R-HSA-5652084 6.834745e-01 0.165 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.834745e-01 0.165 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.834745e-01 0.165 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 6.834745e-01 0.165 0 0
Integrin cell surface interactions R-HSA-216083 6.854412e-01 0.164 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 6.854412e-01 0.164 0 0
MITF-M-dependent gene expression R-HSA-9856651 6.871342e-01 0.163 0 0
Potential therapeutics for SARS R-HSA-9679191 6.871342e-01 0.163 0 0
Signaling by FGFR2 in disease R-HSA-5655253 6.879033e-01 0.162 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 6.951481e-01 0.158 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 6.962264e-01 0.157 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.962264e-01 0.157 0 0
Formation of the ureteric bud R-HSA-9830674 6.962264e-01 0.157 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.962264e-01 0.157 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.055758e-01 0.151 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 7.084653e-01 0.150 0 0
Thromboxane signalling through TP receptor R-HSA-428930 7.084653e-01 0.150 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.084653e-01 0.150 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.084653e-01 0.150 0 0
Mitochondrial RNA degradation R-HSA-9836573 7.084653e-01 0.150 0 0
Complex III assembly R-HSA-9865881 7.084653e-01 0.150 0 0
Interleukin-6 family signaling R-HSA-6783589 7.084653e-01 0.150 0 0
TGFBR3 expression R-HSA-9839394 7.202118e-01 0.143 0 0
Hyaluronan degradation R-HSA-2160916 7.202118e-01 0.143 0 0
Formation of the nephric duct R-HSA-9830364 7.202118e-01 0.143 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.202118e-01 0.143 0 0
Cell surface interactions at the vascular wall R-HSA-202733 7.275880e-01 0.138 0 0
G alpha (q) signalling events R-HSA-416476 7.286691e-01 0.137 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 7.314857e-01 0.136 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.314857e-01 0.136 0 0
MET activates PTK2 signaling R-HSA-8874081 7.314857e-01 0.136 0 0
Urea cycle R-HSA-70635 7.314857e-01 0.136 0 0
Interferon gamma signaling R-HSA-877300 7.333904e-01 0.135 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 7.423059e-01 0.129 0 0
Insulin processing R-HSA-264876 7.423059e-01 0.129 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.423059e-01 0.129 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.423059e-01 0.129 0 0
Maturation of hRSV A proteins R-HSA-9828806 7.423059e-01 0.129 0 0
Dectin-2 family R-HSA-5621480 7.461238e-01 0.127 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 7.526908e-01 0.123 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 7.526908e-01 0.123 0 0
Pyrimidine salvage R-HSA-73614 7.526908e-01 0.123 0 0
Metabolism of non-coding RNA R-HSA-194441 7.609525e-01 0.119 0 0
snRNP Assembly R-HSA-191859 7.609525e-01 0.119 0 0
Extension of Telomeres R-HSA-180786 7.609525e-01 0.119 0 0
Amino acid transport across the plasma membrane R-HSA-352230 7.609525e-01 0.119 0 0
Glucagon-type ligand receptors R-HSA-420092 7.626578e-01 0.118 0 0
DARPP-32 events R-HSA-180024 7.626578e-01 0.118 0 0
tRNA Aminoacylation R-HSA-379724 7.680817e-01 0.115 0 0
Metabolism of polyamines R-HSA-351202 7.680817e-01 0.115 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 7.722237e-01 0.112 0 0
Activation of the pre-replicative complex R-HSA-68962 7.722237e-01 0.112 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.722237e-01 0.112 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.722237e-01 0.112 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.722237e-01 0.112 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.722237e-01 0.112 0 0
Neurotransmitter clearance R-HSA-112311 7.722237e-01 0.112 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.722237e-01 0.112 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 7.722237e-01 0.112 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 7.814046e-01 0.107 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 7.814046e-01 0.107 0 0
Aspartate and asparagine metabolism R-HSA-8963693 7.814046e-01 0.107 0 0
tRNA processing in the nucleus R-HSA-6784531 7.817863e-01 0.107 0 0
Heme signaling R-HSA-9707616 7.817863e-01 0.107 0 0
Signaling by Insulin receptor R-HSA-74752 7.889509e-01 0.103 0 0
Signaling by WNT in cancer R-HSA-4791275 7.902160e-01 0.102 0 0
G alpha (s) signalling events R-HSA-418555 7.913036e-01 0.102 0 0
Bacterial Infection Pathways R-HSA-9824439 7.938848e-01 0.100 0 0
FCGR activation R-HSA-2029481 7.943652e-01 0.100 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 7.943652e-01 0.100 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 7.986727e-01 0.098 0 0
G-protein beta:gamma signalling R-HSA-397795 7.986727e-01 0.098 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.986727e-01 0.098 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 7.986727e-01 0.098 0 0
Cardiogenesis R-HSA-9733709 7.986727e-01 0.098 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 7.986727e-01 0.098 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 8.067891e-01 0.093 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 8.067891e-01 0.093 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.067891e-01 0.093 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.067891e-01 0.093 0 0
Kidney development R-HSA-9830369 8.129775e-01 0.090 0 0
SLC-mediated transport of amino acids R-HSA-9958863 8.129775e-01 0.090 0 0
eNOS activation R-HSA-203615 8.145787e-01 0.089 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 8.145787e-01 0.089 0 0
Hyaluronan metabolism R-HSA-2142845 8.145787e-01 0.089 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.145787e-01 0.089 0 0
Transcription of the HIV genome R-HSA-167172 8.187169e-01 0.087 0 0
Keratinization R-HSA-6805567 8.192069e-01 0.087 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 8.220547e-01 0.085 0 0
RUNX2 regulates bone development R-HSA-8941326 8.292297e-01 0.081 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 8.292297e-01 0.081 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.292297e-01 0.081 0 0
Triglyceride catabolism R-HSA-163560 8.292297e-01 0.081 0 0
RNA Polymerase III Transcription R-HSA-74158 8.292297e-01 0.081 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 8.297244e-01 0.081 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 8.361158e-01 0.078 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 8.361158e-01 0.078 0 0
Collagen chain trimerization R-HSA-8948216 8.361158e-01 0.078 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.427246e-01 0.074 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.427246e-01 0.074 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.427246e-01 0.074 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 8.490674e-01 0.071 0 0
Signaling by FGFR in disease R-HSA-1226099 8.499491e-01 0.071 0 0
Cardiac conduction R-HSA-5576891 8.530308e-01 0.069 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 8.546518e-01 0.068 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 8.551547e-01 0.068 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.551547e-01 0.068 0 0
Tryptophan catabolism R-HSA-71240 8.551547e-01 0.068 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 8.551547e-01 0.068 0 0
Interleukin-2 family signaling R-HSA-451927 8.551547e-01 0.068 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 8.609968e-01 0.065 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 8.609968e-01 0.065 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 8.609968e-01 0.065 0 0
Maturation of spike protein R-HSA-9694548 8.609968e-01 0.065 0 0
G alpha (12/13) signalling events R-HSA-416482 8.679639e-01 0.061 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.719847e-01 0.059 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 8.771490e-01 0.057 0 0
Pyrimidine catabolism R-HSA-73621 8.771490e-01 0.057 0 0
Methylation R-HSA-156581 8.821052e-01 0.054 0 0
Amine ligand-binding receptors R-HSA-375280 8.821052e-01 0.054 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 8.821052e-01 0.054 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.868618e-01 0.052 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 8.868618e-01 0.052 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.876850e-01 0.052 0 0
G alpha (i) signalling events R-HSA-418594 8.944421e-01 0.048 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 8.958078e-01 0.048 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 8.990401e-01 0.046 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 8.990401e-01 0.046 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.000123e-01 0.046 0 0
Metabolism of nucleotides R-HSA-15869 9.006310e-01 0.045 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.014577e-01 0.045 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.040474e-01 0.044 0 0
Peptide hormone metabolism R-HSA-2980736 9.046567e-01 0.044 0 0
Respiratory electron transport R-HSA-611105 9.065874e-01 0.043 0 0
PI3K Cascade R-HSA-109704 9.079199e-01 0.042 0 0
Complex IV assembly R-HSA-9864848 9.116363e-01 0.040 0 0
Neurotransmitter release cycle R-HSA-112310 9.136421e-01 0.039 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.186259e-01 0.037 0 0
Nucleotide biosynthesis R-HSA-8956320 9.186259e-01 0.037 0 0
Paracetamol ADME R-HSA-9753281 9.250633e-01 0.034 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.280888e-01 0.032 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.287173e-01 0.032 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.338903e-01 0.030 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.338903e-01 0.030 0 0
Triglyceride metabolism R-HSA-8979227 9.364527e-01 0.029 0 0
Regulation of beta-cell development R-HSA-186712 9.364527e-01 0.029 0 0
Viral Messenger RNA Synthesis R-HSA-168325 9.414817e-01 0.026 0 0
Aquaporin-mediated transport R-HSA-445717 9.414817e-01 0.026 0 0
Nucleotide salvage R-HSA-8956321 9.414817e-01 0.026 0 0
Collagen degradation R-HSA-1442490 9.414817e-01 0.026 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.438451e-01 0.025 0 0
Complex I biogenesis R-HSA-6799198 9.461132e-01 0.024 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.482898e-01 0.023 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.523833e-01 0.021 0 0
Metabolism of steroid hormones R-HSA-196071 9.543070e-01 0.020 0 0
COPII-mediated vesicle transport R-HSA-204005 9.596249e-01 0.018 0 0
Metabolism of cofactors R-HSA-8978934 9.612565e-01 0.017 0 0
Visual phototransduction R-HSA-2187338 9.654999e-01 0.015 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.657667e-01 0.015 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.709754e-01 0.013 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.721488e-01 0.012 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.721488e-01 0.012 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.754545e-01 0.011 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.799822e-01 0.009 0 0
SLC transporter disorders R-HSA-5619102 9.816197e-01 0.008 0 0
GPCR downstream signalling R-HSA-388396 9.819942e-01 0.008 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.830302e-01 0.007 0 0
Adipogenesis R-HSA-9843745 9.834797e-01 0.007 0 0
tRNA processing R-HSA-72306 9.838325e-01 0.007 0 0
Metabolism of steroids R-HSA-8957322 9.874821e-01 0.005 0 0
Drug ADME R-HSA-9748784 9.882129e-01 0.005 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.892279e-01 0.005 0 0
PI Metabolism R-HSA-1483255 9.904842e-01 0.004 0 0
Platelet homeostasis R-HSA-418346 9.922613e-01 0.003 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.934412e-01 0.003 0 0
PPARA activates gene expression R-HSA-1989781 9.935150e-01 0.003 0 0
Antimicrobial peptides R-HSA-6803157 9.937070e-01 0.003 0 0
Inositol phosphate metabolism R-HSA-1483249 9.939620e-01 0.003 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.939703e-01 0.003 0 0
Signaling by GPCR R-HSA-372790 9.960453e-01 0.002 0 0
Nucleotide catabolism R-HSA-8956319 9.973615e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.977644e-01 0.001 0 0
Diseases of metabolism R-HSA-5668914 9.979714e-01 0.001 0 0
Peptide ligand-binding receptors R-HSA-375276 9.980011e-01 0.001 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.983223e-01 0.001 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.990243e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.991020e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.997038e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.997386e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.997719e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.998431e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999678e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999945e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999957e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999966e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.999979e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999980e-01 0.000 0 0
Metabolism R-HSA-1430728 9.999999e-01 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways