TTBK1
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0MZ66 | S473 | Sugiyama | SHTN1 KIAA1598 | LGtLNKSTSSRsLKsLDPENsEtELERILRRRKVtAEADss |
| A5A3E0 | S1065 | Sugiyama | POTEF A26C1B | ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________ |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | S939 | Sugiyama | POTEF A26C1B | VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE |
| A6NMY6 | S127 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | AQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEINRVy |
| A6NMY6 | T123 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | LKtPAQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEI |
| O00115 | S57 | Sugiyama | DNASE2 DNASE2A DNL2 | ALRGSGEAAQRGLQYKyLDEssGGWRDGRALINsPEGAVGR |
| O00170 | S43 | Sugiyama | AIP XAP2 | GELPDFQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELI |
| O00170 | T48 | Sugiyama | AIP XAP2 | FQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELIIGKKF |
| O00410 | S827 | Sugiyama | IPO5 KPNB3 RANBP5 | NQELRQVKRQDEDyDEQVEEsLQDEDDNDVyILTKVSDILH |
| O00410 | S974 | Sugiyama | IPO5 KPNB3 RANBP5 | VIQSADSKTKENVNAtENCIsAVGKIMKFKPDCVNVEEVLP |
| O00429 | T701 | Sugiyama | DNM1L DLP1 DRP1 | TLQSELVGQLyKsSLLDDLLtESEDMAQRRKEAADMLKALQ |
| O00488 | S98 | Sugiyama | ZNF593 ZT86 | THFRSKDHKKRLKQLsVEPysQEEAERAAGMGSYVPPRRLA |
| O00505 | S60 | Sugiyama | KPNA3 QIP2 | KRDEHLLKKRNVPQEEsLEDsDVDADFKAQNVTLEAILQNA |
| O00592 | T556 | Sugiyama | PODXL PCLP PCLP1 | DsWIVPLDNLTKDDLDEEEDtHL__________________ |
| O15355 | S349 | Sugiyama | PPM1G PPM1C | tTAVVALIRGKQLIVANAGDsRCVVsEAGKALDMsyDHKPE |
| O15355 | S354 | Sugiyama | PPM1G PPM1C | ALIRGKQLIVANAGDsRCVVsEAGKALDMsyDHKPEDEVEL |
| O15371 | T46 | Sugiyama | EIF3D EIF3S7 | RDMPyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGG |
| O15371 | T49 | Sugiyama | EIF3D EIF3S7 | PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY |
| O15372 | S302 | Sugiyama | EIF3H EIF3S3 | QQENMQRQsRGEPPLPEEDLsKLFKPPQPPARMDSLLIAGQ |
| O43324 | S100 | Sugiyama | EEF1E1 AIMP3 P18 | TQVDGHSSKNDIHTLLKDLNsyLEDKVYLTGYNFTLADILL |
| O43423 | S100 | Sugiyama | ANP32CP PP32R1 | AEKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCE |
| O43615 | S193 | Sugiyama | TIMM44 MIMT44 TIM44 | TAAFRALsQGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEF |
| O43707 | S642 | Sugiyama | ACTN4 | KWEKVQQLVPKRDHALLEEQsKQQSNEHLRRQFAsQANVVG |
| O43707 | S900 | Sugiyama | ACTN4 | IARMAPyQGPDAVPGALDyKsFStALyGEsDL_________ |
| O43707 | S909 | Sugiyama | ACTN4 | PDAVPGALDyKsFStALyGEsDL__________________ |
| O43707 | T69 | Sugiyama | ACTN4 | EKQQRKTFTAWCNsHLRKAGtQIENIDEDFRDGLKLMLLLE |
| O43719 | S702 | Sugiyama | HTATSF1 | EDADGKEVEDADEKLFEDDDsNEKLFDEEEDssEKLFDDsD |
| O43847 | S96 | Sugiyama | NRDC NRD1 | SRVARLGADEsEEEGRRGsLsNAGDPEIVKsPsDPKQYRYI |
| O43852 | S125 | Sugiyama | CALU | IyEDVERQWKGHDLNEDGLVsWEEyKNATYGYVLDDPDPDD |
| O43852 | S261 | Sugiyama | CALU | RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK |
| O43852 | S300 | Sugiyama | CALU | NKDGKLTKEEIVDKyDLFVGsQAtDFGEALVRHDEF_____ |
| O43852 | T196 | Sugiyama | CALU | FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD |
| O43852 | T303 | Sugiyama | CALU | GKLTKEEIVDKyDLFVGsQAtDFGEALVRHDEF________ |
| O60216 | S449 | Sugiyama | RAD21 HR21 KIAA0078 NXP1 SCC1 | DQQQQHQQRDVIDEPIIEEPsRLQEsVMEAsRTNIDESAMP |
| O60216 | S454 | Sugiyama | RAD21 HR21 KIAA0078 NXP1 SCC1 | HQQRDVIDEPIIEEPsRLQEsVMEAsRTNIDESAMPPPPPQ |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60566 | S509 | Sugiyama | BUB1B BUBR1 MAD3L SSK1 | IPGMTLSSSVCQVNCCARETsLAENIWQEQPHSKGPsVPFS |
| O60664 | S148 | Sugiyama | PLIN3 M6PRBP1 TIP47 | KVsGAQEMVssAKDTVAtQLsEAVDATRGAVQSGVDKTKsV |
| O60664 | S175 | Sugiyama | PLIN3 M6PRBP1 TIP47 | RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK |
| O60814 | S39 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| O60841 | S113 | Sugiyama | EIF5B IF2 KIAA0741 | sKDKKKKGQKGKKQsFDDNDsEELEDKDsKSKKTAKPKVEM |
| O60841 | S196 | Sugiyama | EIF5B IF2 KIAA0741 | ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN |
| O60841 | S222 | Sugiyama | EIF5B IF2 KIAA0741 | KNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAEKKERERKK |
| O75116 | S930 | Sugiyama | ROCK2 KIAA0619 | SLAAQLEITLTKADSEQLARsIAEEQysDLEKEKIMKELEI |
| O75179 | S209 | Sugiyama | ANKRD17 GTAR KIAA0697 | TADGKAFADPEVLRRLtssVsCALDEAAAALTRMRAEStAN |
| O75347 | S103 | Sugiyama | TBCA | ENEKDLEEAEEyKEARLVLDsVKLEA_______________ |
| O75506 | S31 | Sugiyama | HSBP1 HSF1BP | DLTSVVQTLLQQMQDKFQtMsDQIIGRIDDMSSRIDDLEKN |
| O75534 | S782 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | LDDAsAPRLMVLRQPRGPDNsMGFGAERKIRQAGVID____ |
| O75821 | S217 | Sugiyama | EIF3G EIF3S4 | PGELEPVQAtQNKtGKYVPPsLRDGAsRRGESMQPNRRADD |
| O75821 | S223 | Sugiyama | EIF3G EIF3S4 | VQAtQNKtGKYVPPsLRDGAsRRGESMQPNRRADDNAtIRV |
| O75822 | S127 | Sugiyama | EIF3J EIF3S1 PRO0391 | VLtPEEQLADKLRLKKLQEEsDLELAKEtFGVNNAVyGIDA |
| O94992 | S268 | Sugiyama | HEXIM1 CLP1 EDG1 HIS1 MAQ1 | EDGGsDGMGGDGSEFLQRDFsEtyERyHTEsLQNMsKQELI |
| O94992 | T270 | Sugiyama | HEXIM1 CLP1 EDG1 HIS1 MAQ1 | GGsDGMGGDGSEFLQRDFsEtyERyHTEsLQNMsKQELIKE |
| O95218 | S181 | Sugiyama | ZRANB2 ZIS ZNF265 | DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR |
| O95626 | S104 | Sugiyama | ANP32D PP32R2 | AEKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCE |
| O95678 | S162 | Sugiyama | KRT75 K6HF KB18 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| O95747 | S347 | Sugiyama | OXSR1 KIAA1101 OSR1 | RLHKtEDGGWEWsDDEFDEEsEEGKAAIsQLRsPRVKESIS |
| O95757 | S599 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND |
| O95816 | S208 | Sugiyama | BAG2 | IKLLEHSKGAGSKTLQQNAEsRFN_________________ |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P00338 | S237 | Sugiyama | LDHA PIG19 | DLGtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVA |
| P00338 | T322 | Sugiyama | LDHA PIG19 | DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________ |
| P00441 | S106 | Sugiyama | SOD1 | GNVtADKDGVADVsIEDsVIsLsGDHCIIGRTLVVHEKADD |
| P00441 | S99 | Sugiyama | SOD1 | ERHVGDLGNVtADKDGVADVsIEDsVIsLsGDHCIIGRTLV |
| P00558 | S174 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P02538 | S176 | Sugiyama | KRT6A K6A KRT6D | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT |
| P04075 | S17 | Sugiyama | ALDOA ALDA | ____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T125 | Sugiyama | ALDOA ALDA | VGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGADF |
| P04075 | T37 | Sugiyama | ALDOA ALDA | sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR |
| P04083 | S170 | Sugiyama | ANXA1 ANX1 LPC1 | RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE |
| P04083 | S189 | Sugiyama | ANXA1 ANX1 LPC1 | tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA |
| P04259 | S176 | Sugiyama | KRT6B K6B KRTL1 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T211 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P04792 | S83 | Sugiyama | HSPB1 HSP27 HSP28 | IEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNH |
| P04792 | S86 | Sugiyama | HSPB1 HSP27 HSP28 | PAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAP |
| P05386 | S101 | Sugiyama | RPLP1 RRP1 | APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______ |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S102 | Sugiyama | RPLP2 D11S2243E RPP2 | PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S29 | Sugiyama | RPLP2 D11S2243E RPP2 | LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK |
| P05455 | S325 | Sugiyama | SSB | VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA |
| P05787 | S104 | Sugiyama | KRT8 CYK8 | IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS |
| P05787 | S258 | Sugiyama | KRT8 CYK8 | QISDTSVVLsMDNSRsLDMDsIIAEVKAQyEDIANRsRAEA |
| P05787 | S291 | Sugiyama | KRT8 CYK8 | ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN |
| P05787 | S410 | Sugiyama | KRT8 CYK8 | TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL |
| P05787 | S475 | Sugiyama | KRT8 CYK8 | TSSSRAVVVKKIETRDGKLVsEssDVLPK____________ |
| P06703 | S46 | Sugiyama | S100A6 CACY | KHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRNKDQ |
| P06703 | T43 | Sugiyama | S100A6 CACY | EGDKHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRN |
| P06733 | S104 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCKAGAV |
| P06733 | S14 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | S40 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK |
| P06733 | S79 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GKGVSKAVEHINKtIAPALVsKKLNVtEQEKIDKLMIEMDG |
| P06733 | T100 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK |
| P06733 | T19 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T26 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | T72 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NDKtRYMGKGVSKAVEHINKtIAPALVsKKLNVtEQEKIDK |
| P06748 | S125 | Sugiyama | NPM1 NPM | GsGPVHIsGQHLVAVEEDAEsEDEEEEDVKLLsIsGKRsAP |
| P06748 | S137 | Sugiyama | NPM1 NPM | VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK |
| P06748 | S43 | Sugiyama | NPM1 NPM | LKADKDyHFKVDNDENEHQLsLRTVsLGAGAKDELHIVEAE |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T18 | Sugiyama | LDHB | ___MATLKEKLIAPVAEEEAtVPNNKITVVGVGQVGMACAI |
| P07195 | T302 | Sugiyama | LDHB | YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD |
| P07237 | S427 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | WDKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFP |
| P07237 | S88 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG |
| P07237 | T428 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | DKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFPA |
| P07237 | T453 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | EAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESG |
| P07237 | T85 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | KAAGKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFF |
| P07355 | S127 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | AQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEINRVy |
| P07355 | T123 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | LKtPAQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEI |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | S168 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS |
| P07437 | S275 | iPTMNet|EPSD | TUBB TUBB5 OK/SW-cl.56 | VNMVPFPRLHFFMPGFAPLtsRGsQQyRALtVPELtQQVFD |
| P07437 | T107 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC |
| P07437 | T166 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | GMGTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT |
| P07437 | Y106 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAES |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07814 | S335 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt |
| P07814 | S880 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | LKAQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPE |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S50 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S623 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | tyGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsII |
| P07900 | S641 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD |
| P07900 | T195 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG |
| P07900 | T305 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IDQEELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLA |
| P07900 | T624 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE |
| P07900 | T645 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL |
| P07900 | T88 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | sKLDsGKELHINLIPNKQDRtLtIVDtGIGMTKADLINNLG |
| P07900 | T90 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | LDsGKELHINLIPNKQDRtLtIVDtGIGMTKADLINNLGtI |
| P07919 | T63 | Sugiyama | UQCRH | CVKARERLELCDERVssRsHtEEDCtEELFDFLHARDHCVA |
| P07919 | T68 | Sugiyama | UQCRH | ERLELCDERVssRsHtEEDCtEELFDFLHARDHCVAHKLFN |
| P07951 | S245 | Sugiyama | TPM2 TMSB | IKLLEEKLKEAEtRAEFAERsVAKLEKtIDDLEDEVyAQKM |
| P07951 | T237 | Sugiyama | TPM2 TMSB | KEDKyEEEIKLLEEKLKEAEtRAEFAERsVAKLEKtIDDLE |
| P07951 | T282 | Sugiyama | TPM2 TMSB | AQKMKYKAIsEELDNALNDItsL__________________ |
| P08133 | T385 | Sugiyama | ANXA6 ANX6 | PDADAKALRKAMKGLGTDEDtIIDIItHRSNVQRQQIRQTF |
| P08133 | T391 | Sugiyama | ANXA6 ANX6 | ALRKAMKGLGTDEDtIIDIItHRSNVQRQQIRQTFKSHFGR |
| P08195 | S292 | Sugiyama | SLC3A2 MDU1 | VAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNY |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | S532 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | yMtEPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK |
| P08238 | S535 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| P08238 | T190 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG |
| P08238 | T297 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IDQEELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLA |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | T537 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK |
| P08238 | T637 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL |
| P08670 | S459 | Sugiyama | VIM | KRTLLIKtVEtRDGQVINEtsQHHDDLE_____________ |
| P08729 | S104 | Sugiyama | KRT7 SCL | LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT |
| P08758 | T10 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | ___________MAQVLRGtVtDFPGFDERADAEtLRKAMKG |
| P08758 | Y129 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | VLtEIIAsRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYY |
| P08865 | S75 | Sugiyama | RPSA LAMBR LAMR1 | WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG |
| P09104 | S37 | Sugiyama | ENO2 | NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY |
| P09104 | S40 | Sugiyama | ENO2 | VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P09382 | T58 | Sugiyama | LGALS1 | DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF |
| P09493 | T282 | Sugiyama | TPM1 C15orf13 TMSA | AQKLKYKAISEELDHALNDMtsI__________________ |
| P09661 | T250 | Sugiyama | SNRPA1 | PGRERRsGPtDDGEEEMEEDtVtNGS_______________ |
| P09661 | T252 | Sugiyama | SNRPA1 | RERRsGPtDDGEEEMEEDtVtNGS_________________ |
| P09972 | S132 | Sugiyama | ALDOC ALDC | GVVPLAGtDGEtttQGLDGLsERCAQYKKDGADFAKWRCVL |
| P09972 | S36 | Sugiyama | ALDOC ALDC | LsDIALRIVAPGKGILAADEsVGsMAKRLsQIGVENtEENR |
| P09972 | S39 | Sugiyama | ALDOC ALDC | IALRIVAPGKGILAADEsVGsMAKRLsQIGVENtEENRRLY |
| P0CG38 | S1065 | Sugiyama | POTEI | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1028 | Sugiyama | POTEJ | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0DPH7 | S287 | Sugiyama | TUBA3C TUBA2 | FPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDP |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | S54 | Sugiyama | TUBA3C TUBA2 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P0DPH7 | T292 | Sugiyama | TUBA3C TUBA2 | yAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDPRHGKY |
| P0DPH7 | T41 | Sugiyama | TUBA3C TUBA2 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| P0DPH7 | Y282 | Sugiyama | TUBA3C TUBA2 | yPRIHFPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQM |
| P10412 | S41 | Sugiyama | H1-4 H1F4 HIST1H1E | KKKARKsAGAAKRKAsGPPVsELItKAVAASKERsGVsLAA |
| P10412 | T45 | Sugiyama | H1-4 H1F4 HIST1H1E | RKsAGAAKRKAsGPPVsELItKAVAASKERsGVsLAALKKA |
| P10636 | S515 | GPS6|SIGNOR|EPSD | MAPT MAPTL MTBT1 TAU | APKtPPsSGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtP |
| P10636 | S516 | GPS6|SIGNOR | MAPT MAPTL MTBT1 TAU | PKtPPsSGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtPP |
| P10636 | S519 | GPS6|SIGNOR | MAPT MAPTL MTBT1 TAU | PPsSGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPtPPTRE |
| P10636 | S733 | GPS6 | MAPT MAPTL MTBT1 TAU | sPVVsGDtsPRHLsNVsstGsIDMVDsPQLAtLADEVSASL |
| P10636 | S739 | GPS6|SIGNOR | MAPT MAPTL MTBT1 TAU | DtsPRHLsNVsstGsIDMVDsPQLAtLADEVSASLAKQGL_ |
| P10636 | T744 | GPS6|EPSD | MAPT MAPTL MTBT1 TAU | HLsNVsstGsIDMVDsPQLAtLADEVSASLAKQGL______ |
| P10636 | Y514 | EPSD | MAPT MAPTL MTBT1 TAU | PAPKtPPsSGEPPKsGDRsGyssPGsPGtPGsRsRtPsLPt |
| P10809 | S187 | Sugiyama | HSPD1 HSP60 | EIAQVAtIsANGDKEIGNIIsDAMKKVGRKGVITVKDGKtL |
| P10809 | S453 | Sugiyama | HSPD1 HSP60 | EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK |
| P10809 | S488 | Sugiyama | HSPD1 HSP60 | IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG |
| P10809 | S67 | Sugiyama | HSPD1 HSP60 | LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK |
| P10809 | T206 | Sugiyama | HSPD1 HSP60 | IsDAMKKVGRKGVITVKDGKtLNDELEIIEGMKFDRGyIsP |
| P10809 | T455 | Sugiyama | HSPD1 HSP60 | GIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLKIP |
| P11142 | S544 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KYKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKIND |
| P11142 | S85 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11586 | S129 | Sugiyama | MTHFD1 MTHFC MTHFD | INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP |
| P11586 | S771 | Sugiyama | MTHFD1 MTHFC MTHFD | PVVVAVNAFKTDTEsELDLIsRLSREHGAFDAVKCTHWAEG |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P12035 | S211 | Sugiyama | KRT3 | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | T5 | Sugiyama | EEF2 EF2 | ________________MVNFtVDQIRAIMDKKANIRNMsVI |
| P13647 | S181 | Sugiyama | KRT5 | IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P13667 | S468 | Sugiyama | PDIA4 ERP70 ERP72 | ytFAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAM |
| P13667 | S470 | Sugiyama | PDIA4 ERP70 ERP72 | FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP |
| P13693 | S15 | Sugiyama | TPT1 | ______MIIYRDLIsHDEMFsDIyKIREIADGLCLEVEGKM |
| P13693 | S9 | Sugiyama | TPT1 | ____________MIIYRDLIsHDEMFsDIyKIREIADGLCL |
| P13798 | S185 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | VAEKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQ |
| P13929 | S37 | Sugiyama | ENO3 | NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY |
| P13929 | S40 | Sugiyama | ENO3 | VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14314 | T115 | Sugiyama | PRKCSH G19P1 | GVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQQMAEVtR |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S205 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD |
| P14618 | S55 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | IDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMNVARLN |
| P14618 | T195 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | yVDDGLISLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAA |
| P14618 | T41 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | AMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtL |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | S523 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | RtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAG |
| P14625 | T522 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | NRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMA |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14649 | T101 | Sugiyama | MYL6B MLC1SA | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDELKSRR |
| P15311 | S539 | Sugiyama | EZR VIL2 | TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR |
| P15311 | T533 | Sugiyama | EZR VIL2 | NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15531 | S125 | Sugiyama | NME1 NDPKA NM23 | RGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDyTsC |
| P16083 | S80 | Sugiyama | NQO2 NMOR2 | LSNPEVFNyGVEtHEAyKQRsLAsDITDEQKKVREADLVIF |
| P16402 | S42 | Sugiyama | H1-3 H1F3 HIST1H1D | KKAKKAGATAGKRKAsGPPVsELItKAVAASKERsGVsLAA |
| P16402 | T46 | Sugiyama | H1-3 H1F3 HIST1H1D | KAGATAGKRKAsGPPVsELItKAVAASKERsGVsLAALKKA |
| P16403 | S41 | Sugiyama | H1-2 H1F2 HIST1H1C | KKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsGVsLAA |
| P16403 | T45 | Sugiyama | H1-2 H1F2 HIST1H1C | AKKAGGtPRKAsGPPVsELItKAVAASKERsGVsLAALKKA |
| P17066 | T228 | Sugiyama | HSPA6 HSP70B' | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P17096 | S102 | Sugiyama | HMGA1 HMGIY | KPRGRPKKLEKEEEEGIsQEssEEEQ_______________ |
| P17096 | S99 | Sugiyama | HMGA1 HMGIY | PGRKPRGRPKKLEKEEEEGIsQEssEEEQ____________ |
| P17812 | S578 | Sugiyama | CTPS1 CTPS | GCRLsPRDtysDRsGsssPDsEItELKFPsINHD_______ |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18084 | S507 | Sugiyama | ITGB5 | CECSPGYLGTRCECQDGENQsVyQNLCREAEGKPLCSGRGD |
| P18621 | S111 | Sugiyama | RPL17 | LLHMLKNAESNAELKGLDVDsLVIEHIQVNKAPKMRRRTYR |
| P19338 | S458 | Sugiyama | NCL | TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P19338 | Y463 | Sugiyama | NCL | EKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsG |
| P20042 | S105 | Sugiyama | EIF2S2 EIF2B | TKKIFDIDEAEEGVKDLKIEsDVQEPtEPEDDLDIMLGNKK |
| P20042 | S39 | Sugiyama | EIF2S2 EIF2B | KKKPFMLDEEGDtQtEEtQPsETKEVEPEPtEDKDLEADEE |
| P20042 | S67 | Sugiyama | EIF2S2 EIF2B | EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK |
| P20042 | T111 | Sugiyama | EIF2S2 EIF2B | IDEAEEGVKDLKIEsDVQEPtEPEDDLDIMLGNKKKKKKNV |
| P20042 | T33 | Sugiyama | EIF2S2 EIF2B | sKKKKKKKKPFMLDEEGDtQtEEtQPsETKEVEPEPtEDKD |
| P20290 | S201 | Sugiyama | BTF3 NACB OK/SW-cl.8 | AtGEDDDDEVPDLVENFDEAsKNEAN_______________ |
| P20810 | S287 | Sugiyama | CAST | TVRsAAPPQEKKRKVEKDtMsDQALEALsAsLGTRQAEPEL |
| P20810 | S295 | Sugiyama | CAST | QEKKRKVEKDtMsDQALEALsAsLGTRQAEPELDLRsIKEV |
| P20810 | S311 | Sugiyama | CAST | LEALsAsLGTRQAEPELDLRsIKEVDEAKAKEEKLEKCGED |
| P20810 | S337 | Sugiyama | CAST | EAKAKEEKLEKCGEDDEtIPsEyRLKPATDKDGKPLLPEPE |
| P20810 | S373 | Sugiyama | CAST | LPEPEEKPKPRsEsELIDELsEDFDRsECKEKPSKPTEKTE |
| P20810 | S379 | Sugiyama | CAST | KPKPRsEsELIDELsEDFDRsECKEKPSKPTEKTEESKAAA |
| P21127 | S277 | Sugiyama | CDK11B CDC2L1 CDK11 PITSLREA PK58 | APAQKPAQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSA |
| P21127 | S283 | Sugiyama | CDK11B CDC2L1 CDK11 PITSLREA PK58 | AQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSAESGSGS |
| P22234 | S35 | Sugiyama | PAICS ADE2 AIRC PAIS | EGKtKEVyELLDsPGKVLLQsKDQItAGNAARKNHLEGKAA |
| P22234 | T40 | Sugiyama | PAICS ADE2 AIRC PAIS | EVyELLDsPGKVLLQsKDQItAGNAARKNHLEGKAAISNKI |
| P22314 | S46 | Sugiyama | UBA1 A1S9T UBE1 | AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA |
| P22626 | S351 | Sugiyama | HNRNPA2B1 HNRPA2B1 | yGGGNyGPGGsGGsGGyGGRsRy__________________ |
| P22626 | Y353 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GGNyGPGGsGGsGGyGGRsRy____________________ |
| P23434 | S150 | Sugiyama | GCSH | NPGLVNKSCyEDGWLIKMtLsNPsELDELMsEEAyEKYIKS |
| P23434 | S153 | Sugiyama | GCSH | LVNKSCyEDGWLIKMtLsNPsELDELMsEEAyEKYIKSIEE |
| P23434 | S160 | Sugiyama | GCSH | EDGWLIKMtLsNPsELDELMsEEAyEKYIKSIEE_______ |
| P23434 | Y164 | Sugiyama | GCSH | LIKMtLsNPsELDELMsEEAyEKYIKSIEE___________ |
| P23528 | T63 | Sugiyama | CFL1 CFL | DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P23588 | S207 | Sugiyama | EIF4B | DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR |
| P23588 | T205 | Sugiyama | EIF4B | GRDRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYR |
| P24534 | S141 | Sugiyama | EEF1B2 EEF1B EF1B | ERLAQYESKKAKKPALVAKssILLDVKPWDDEtDMAKLEEC |
| P24534 | T153 | Sugiyama | EEF1B2 EEF1B EF1B | KPALVAKssILLDVKPWDDEtDMAKLEECVRsIQADGLVWG |
| P25205 | S34 | Sugiyama | MCM3 | EAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVNDL |
| P25705 | S53 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | ARNFHASNTHLQKtGtAEMssILEERILGADtsVDLEETGR |
| P25786 | S211 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | GLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDDDVsP |
| P25786 | T206 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | ELVKHGLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDD |
| P25786 | T207 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | LVKHGLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDD |
| P25788 | S243 | Sugiyama | PSMA3 HC8 PSC8 | GRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM________ |
| P25788 | S250 | Sugiyama | PSMA3 HC8 PSC8 | KDIREEAEKyAKEsLKEEDEsDDDNM_______________ |
| P26038 | S527 | Sugiyama | MSN | ERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHAE |
| P26038 | S576 | Sugiyama | MSN | YKtLRQIRQGNTKQRIDEFEsM___________________ |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | T148 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV |
| P26373 | T151 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE |
| P26639 | S522 | Sugiyama | TARS1 TARS | PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP |
| P26639 | S702 | Sugiyama | TARS1 TARS | ISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEE |
| P26639 | T700 | Sugiyama | TARS1 TARS | EKISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAE |
| P27348 | T30 | Sugiyama | YWHAQ | AKLAEQAERyDDMAtCMKAVtEQGAELsNEERNLLsVAyKN |
| P27797 | S189 | Sugiyama | CALR CRTC | THLytLIVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIK |
| P27797 | S193 | Sugiyama | CALR CRTC | tLIVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDA |
| P27797 | S195 | Sugiyama | CALR CRTC | IVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDAsK |
| P27797 | S214 | Sugiyama | CALR CRTC | GsLEDDWDFLPPKKIKDPDAsKPEDWDERAKIDDPtDsKPE |
| P27797 | S35 | Sugiyama | CALR CRTC | AVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGK |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P27816 | S440 | Sugiyama | MAP4 | QANDIISSTEISSAEKVALssETEVALARDMtLPPETNVIL |
| P27816 | S60 | Sugiyama | MAP4 | ETVGKTDyIPLLDVDEKtGNsESKKKPCsEtsQIEDtPSSK |
| P27816 | S643 | Sugiyama | MAP4 | IsPEtVTGtGKKCsLPAEEDsVLEKLGERKPCNsQPSELSS |
| P27816 | T57 | Sugiyama | MAP4 | VVGETVGKTDyIPLLDVDEKtGNsESKKKPCsEtsQIEDtP |
| P28066 | S179 | Sugiyama | PSMA5 | sGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSL |
| P28066 | S180 | Sugiyama | PSMA5 | GtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSLI |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | T287 | Sugiyama | TKT | AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S60 | Sugiyama | EEF1D EF1D | ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL |
| P30040 | T43 | Sugiyama | ERP29 C12orf8 ERP28 | LLSAPHGGSGLHTKGALPLDtVtFyKVIPKSKFVLVKFDtQ |
| P30040 | T45 | Sugiyama | ERP29 C12orf8 ERP28 | SAPHGGSGLHTKGALPLDtVtFyKVIPKSKFVLVKFDtQyP |
| P30041 | T95 | Sugiyama | PRDX6 AOP2 KIAA0106 | SVEDHLAWSKDINAyNCEEPtEKLPFPIIDDRNRELAILLG |
| P30044 | S168 | Sugiyama | PRDX5 ACR1 SBBI10 | RLLADPTGAFGKEtDLLLDDsLVsIFGNRRLKRFsMVVQDG |
| P30044 | S171 | Sugiyama | PRDX5 ACR1 SBBI10 | ADPTGAFGKEtDLLLDDsLVsIFGNRRLKRFsMVVQDGIVK |
| P30050 | S157 | Sugiyama | RPL12 | QsVGCNVDGRHPHDIIDDINsGAVECPAs____________ |
| P30050 | S165 | Sugiyama | RPL12 | GRHPHDIIDDINsGAVECPAs____________________ |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | S54 | Sugiyama | PEBP1 PBP PEBP | VDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAP |
| P30101 | S165 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | FKKFISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYRFA |
| P30101 | S169 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | ISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYRFAHTNV |
| P30101 | S474 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | yFsPANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEK |
| P30101 | S478 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | ANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKK |
| P30101 | T485 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKKKAQEDL |
| P30622 | S1321 | Sugiyama | CLIP1 CYLN1 RSN | LSsssGNtDTQADEDERAQEsQIDFLNsVIVDLQRKNQDLK |
| P30622 | S1328 | Sugiyama | CLIP1 CYLN1 RSN | tDTQADEDERAQEsQIDFLNsVIVDLQRKNQDLKMKVEMMS |
| P31150 | S316 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM |
| P31153 | S38 | Sugiyama | MAT2A AMS2 MATA2 | FLFTSESVGEGHPDKICDQIsDAVLDAHLQQDPDAKVACET |
| P31327 | S1090 | Sugiyama | CPS1 | KNGVKIMGTsPLQIDRAEDRsIFsAVLDELKVAQAPWKAVN |
| P31327 | S1093 | Sugiyama | CPS1 | VKIMGTsPLQIDRAEDRsIFsAVLDELKVAQAPWKAVNTLN |
| P31327 | S205 | Sugiyama | CPS1 | FEGQPVDFVDPNKQNLIAEVstKDVKVYGKGNPTKVVAVDC |
| P31327 | S564 | Sugiyama | CPS1 | TEDRQLFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPV |
| P31327 | S569 | Sugiyama | CPS1 | LFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPVMIRSA |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P31947 | S37 | Sugiyama | SFN HME1 | ERyEDMAAFMKGAVEKGEELsCEERNLLsVAyKNVVGGQRA |
| P31948 | S16 | Sugiyama | STIP1 | _____MEQVNELKEKGNKALsVGNIDDALQCysEAIKLDPH |
| P31948 | S28 | Sugiyama | STIP1 | KEKGNKALsVGNIDDALQCysEAIKLDPHNHVLysNRsAAy |
| P31948 | S459 | Sugiyama | STIP1 | EAMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRH |
| P31948 | S460 | Sugiyama | STIP1 | AMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRHD |
| P32119 | T142 | Sugiyama | PRDX2 NKEFB TDPX1 | EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF |
| P33176 | S443 | Sugiyama | KIF5B KNS KNS1 | EEIAKLYKQLDDKDEEINQQsQLVEKLKTQMLDQEELLAST |
| P33176 | S950 | Sugiyama | KIF5B KNS KNS1 | PAAsPtHPSAIRGGGAFVQNsQPVAVRGGGGKQV_______ |
| P34931 | T228 | Sugiyama | HSPA1L | DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK |
| P35579 | S1154 | Sugiyama | MYH9 | KRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKK |
| P35579 | S1304 | Sugiyama | MYH9 | NVtGLLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQK |
| P35579 | S1308 | Sugiyama | MYH9 | LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs |
| P35579 | S169 | Sugiyama | MYH9 | HIyAITDtAyRSMMQDREDQsILCTGESGAGKTENTKKVIQ |
| P35579 | S1892 | Sugiyama | MYH9 | LKQLKRQLEEAEEEAQRANAsRRKLQRELEDAtEtADAMNR |
| P35579 | S1915 | Sugiyama | MYH9 | KLQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMA |
| P35579 | T1155 | Sugiyama | MYH9 | RDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKKT |
| P35579 | T1904 | Sugiyama | MYH9 | EEAQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRG |
| P35579 | T1906 | Sugiyama | MYH9 | AQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRGDL |
| P35606 | S787 | Sugiyama | COPB2 | SRVVKLWRENLSKVNQKAAEsLADPtEyENLFPGLKEAFVV |
| P35606 | T792 | Sugiyama | COPB2 | LWRENLSKVNQKAAEsLADPtEyENLFPGLKEAFVVEEWVK |
| P35659 | S230 | Sugiyama | DEK | sSGMARKAKRTKCPEILsDEsssDEDEKKNKEEssDDEDKE |
| P35908 | S191 | Sugiyama | KRT2 KRT2A KRT2E | IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| P35998 | S89 | Sugiyama | PSMC2 MSS1 | DTGLAPPALWDLAADKQTLQsEQPLQVARCTKIINADSEDP |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P36578 | T84 | Sugiyama | RPL4 RPL1 | AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP |
| P37802 | S163 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37802 | T190 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________ |
| P37802 | Y192 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________ |
| P37837 | S13 | Sugiyama | TALDO1 TAL TALDO TALDOR | ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | T111 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VAFtADGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDP |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P38646 | T120 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV |
| P39023 | S265 | Sugiyama | RPL3 OK/SW-cl.32 | HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY |
| P39687 | S104 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | AEKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCE |
| P39687 | S117 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | GNKIKDLstIEPLKKLENLKsLDLFNCEVtNLNDyRENVFK |
| P39687 | T126 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | IEPLKKLENLKsLDLFNCEVtNLNDyRENVFKLLPQLtyLD |
| P41236 | S24 | Sugiyama | PPP1R2 IPP2 | STAsHRPIKGILKNKtsttssMVAsAEQPRGNVDEELSKKs |
| P42224 | S640 | Sugiyama | STAT1 | SQNGGEPDFHAVEPYTKKELsAVtFPDIIRNYKVMAAENIP |
| P42224 | T643 | Sugiyama | STAT1 | GGEPDFHAVEPYTKKELsAVtFPDIIRNYKVMAAENIPENP |
| P43034 | S152 | Sugiyama | PAFAH1B1 LIS1 MDCR MDS PAFAHA | IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM |
| P43034 | S157 | Sugiyama | PAFAH1B1 LIS1 MDCR MDS PAFAHA | yEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADMTIKLW |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P46109 | S12 | Sugiyama | CRKL | _________MSSARFDssDRsAWyMGPVsRQEAQtRLQGQR |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46776 | T72 | Sugiyama | RPL27A | yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46783 | S146 | Sugiyama | RPS10 | TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_ |
| P46783 | T148 | Sugiyama | RPS10 | RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___ |
| P47756 | S204 | Sugiyama | CAPZB | sGtMNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKI |
| P47756 | T202 | Sugiyama | CAPZB | SGsGtMNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMEN |
| P47914 | S142 | Sugiyama | RPL29 | KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___ |
| P48444 | S244 | Sugiyama | ARCN1 COPD | KALKLGAKGKEVDNFVDKLKsEGEtIMSssMGKRTSEATKM |
| P48444 | T248 | Sugiyama | ARCN1 COPD | LGAKGKEVDNFVDKLKsEGEtIMSssMGKRTSEATKMHAPP |
| P48668 | S176 | Sugiyama | KRT6C KRT6E | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P48741 | T228 | Sugiyama | HSPA7 HSP70B | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P49321 | S176 | Sugiyama | NASP | EAKKTEDKSLAKPEtDKEQDsEMEKGGREDMDIsKsAEEPQ |
| P49327 | S2198 | Sugiyama | FASN FAS | EVRQLTLRKLQELSSKADEAsELACPtPKEDGLAQQQtQLN |
| P49589 | S305 | Sugiyama | CARS1 CARS | KLVPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKA |
| P49589 | S312 | Sugiyama | CARS1 CARS | GDQKALQEGEGDLsIsADRLsEKRSPNDFALWKASKPGEPS |
| P49736 | T25 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | sEsFtMAssPAQRRRGNDPLtssPGRssRRtDALtssPGRD |
| P50395 | S316 | Sugiyama | GDI2 RABGDIB | QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM |
| P50454 | S138 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | LSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEH |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50454 | S141 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI |
| P50454 | S149 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | KLGsRLyGPssVsFADDFVRssKQHYNCEHSKINFRDKRSA |
| P50502 | S218 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | WEEAAHDLALACKLDyDEDAsAMLKEVQPRAQKIAEHRRKY |
| P50502 | S76 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | KEEKPDSKKVEEDLKADEPssEEsDLEIDKEGVIEPDTDAP |
| P50897 | S262 | Sugiyama | PPT1 CLN1 PPT | EWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLVF |
| P50897 | T261 | Sugiyama | PPT1 CLN1 PPT | SEWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLV |
| P51858 | S40 | Sugiyama | HDGF HMG1L2 | MKGyPHWPARIDEMPEAAVKstANKYQVFFFGTHETAFLGP |
| P51858 | S83 | Sugiyama | HDGF HMG1L2 | LFPyEEsKEKFGKPNKRKGFsEGLWEIENNPtVKASGYQSs |
| P51858 | T184 | Sugiyama | HDGF HMG1L2 | DsPKRPKEAENPEGEEKEAAtLEVERPLPMEVEKNstPsEP |
| P51858 | T41 | Sugiyama | HDGF HMG1L2 | KGyPHWPARIDEMPEAAVKstANKYQVFFFGTHETAFLGPK |
| P51858 | T94 | Sugiyama | HDGF HMG1L2 | GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP |
| P52597 | S279 | Sugiyama | HNRNPF HNRPF | LFGRDLsyCLsGMyDHRYGDsEFtVQsTTGHCVHMRGLPYK |
| P52597 | S285 | Sugiyama | HNRNPF HNRPF | syCLsGMyDHRYGDsEFtVQsTTGHCVHMRGLPYKAtENDI |
| P52597 | T282 | Sugiyama | HNRNPF HNRPF | RDLsyCLsGMyDHRYGDsEFtVQsTTGHCVHMRGLPYKAtE |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P53396 | S459 | Sugiyama | ACLY | LNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMPQDsV |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P53999 | S17 | Sugiyama | SUB1 PC4 RPO2TC1 | ____MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPV |
| P53999 | S57 | Sugiyama | SUB1 PC4 RPO2TC1 | VKKQKTGETsRALsssKQssssRDDNMFQIGKMRYVSVRDF |
| P54105 | T225 | Sugiyama | CLNS1A CLCI ICLN | VRtEDsIRDyEDGMEVDttPtVAGQFEDADVDH________ |
| P54105 | Y214 | Sugiyama | CLNS1A CLCI ICLN | QsVssQYNMAGVRtEDsIRDyEDGMEVDttPtVAGQFEDAD |
| P54578 | S228 | Sugiyama | USP14 TGT | MRVLQQKLEAIEDDsVKETDsssAsAAtPSKKKSLIDQFFG |
| P54578 | S230 | Sugiyama | USP14 TGT | VLQQKLEAIEDDsVKETDsssAsAAtPSKKKSLIDQFFGVE |
| P55036 | S266 | Sugiyama | PSMD4 MCB1 | AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ |
| P55036 | S358 | Sugiyama | PSMD4 MCB1 | VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_ |
| P55036 | S361 | Sugiyama | PSMD4 MCB1 | NLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK____ |
| P55060 | S342 | Sugiyama | CSE1L CAS XPO2 | ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF |
| P55060 | S366 | Sugiyama | CSE1L CAS XPO2 | KVIVPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAA |
| P55072 | S37 | Sugiyama | VCP HEL-220 HEL-S-70 | LKQKNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTV |
| P55072 | S40 | Sugiyama | VCP HEL-220 HEL-S-70 | KNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTVLLK |
| P55072 | T14 | Sugiyama | VCP HEL-220 HEL-S-70 | _______MAsGADsKGDDLstAILKQKNRPNRLIVDEAINE |
| P55209 | S10 | Sugiyama | NAP1L1 NRP | ___________MADIDNKEQsELDQDLDDVEEVEEEEtGEE |
| P55957 | S76 | Sugiyama | BID | ELQtDGNRssHsRLGRIEADsEsQEDIIRNIARHLAQVGDs |
| P57053 | S39 | Sugiyama | H2BC12L H2BFS H2BS1 | VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P57721 | S82 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK |
| P58876 | S39 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60174 | T38 | Sugiyama | TPI1 TPI | RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP |
| P60174 | T46 | Sugiyama | TPI1 TPI | IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60660 | T44 | Sugiyama | MYL6 | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDEMNVKV |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S239 | Sugiyama | ACTB | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S365 | Sugiyama | ACTB | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | S60 | Sugiyama | ACTB | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P60709 | T202 | Sugiyama | ACTB | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P60709 | T203 | Sugiyama | ACTB | RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF |
| P60709 | T318 | Sugiyama | ACTB | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P60709 | Y53 | Sugiyama | ACTB | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P61247 | S203 | Sugiyama | RPS3A FTE1 MFTL | EVVNKLIPDsIGKDIEKACQsIyPLHDVFVRKVKMLKKPKF |
| P61247 | S236 | Sugiyama | RPS3A FTE1 MFTL | KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61247 | Y205 | Sugiyama | RPS3A FTE1 MFTL | VNKLIPDsIGKDIEKACQsIyPLHDVFVRKVKMLKKPKFEL |
| P61313 | S100 | Sugiyama | RPL15 EC45 TCBAP0781 | tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW |
| P61313 | S97 | Sugiyama | RPL15 EC45 TCBAP0781 | KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN |
| P61353 | S34 | Sugiyama | RPL27 | LAGRYSGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVT |
| P61353 | S39 | Sugiyama | RPL27 | SGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMGK |
| P61353 | Y38 | Sugiyama | RPL27 | YSGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMG |
| P61604 | S21 | Sugiyama | HSPE1 | MAGQAFRKFLPLFDRVLVERsAAETVTKGGIMLPEKSQGKV |
| P61604 | S64 | Sugiyama | HSPE1 | AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | S38 | Sugiyama | YWHAG | ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS |
| P61981 | T31 | Sugiyama | YWHAG | ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN |
| P62136 | S11 | Sugiyama | PPP1CA PPP1A | __________MsDsEKLNLDsIIGRLLEVQGsRPGKNVQLT |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S210 | Sugiyama | YWHAE | RACRLAKAAFDDAIAELDtLsEEsyKDstLIMQLLRDNLtL |
| P62266 | S45 | Sugiyama | RPS23 | KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62269 | T60 | Sugiyama | RPS18 D6S218E | YAHVVLRKADIDLTKRAGELtEDEVERVItIMQNPRQYKIP |
| P62269 | T69 | Sugiyama | RPS18 D6S218E | DIDLTKRAGELtEDEVERVItIMQNPRQYKIPDWFLNRQKD |
| P62273 | S9 | Sugiyama | RPS29 | ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG |
| P62277 | S12 | Sugiyama | RPS13 | _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD |
| P62280 | T15 | Sugiyama | RPS11 | ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR |
| P62633 | S121 | Sugiyama | CNBP RNF163 ZNF9 | CGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRCG |
| P62633 | Y120 | Sugiyama | CNBP RNF163 ZNF9 | NCGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRC |
| P62736 | S241 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | S62 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P62736 | T320 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P62736 | Y55 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P62753 | S6 | Sugiyama | RPS6 OK/SW-cl.2 | _______________MKLNIsFPAtGCQKLIEVDDERKLRt |
| P62753 | T10 | Sugiyama | RPS6 OK/SW-cl.2 | ___________MKLNIsFPAtGCQKLIEVDDERKLRtFyEK |
| P62807 | S39 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA |
| P62851 | S74 | Sugiyama | RPS25 | tyDKLCKEVPNYKLItPAVVsERLKIRGSLARAALQELLsK |
| P62854 | S54 | Sugiyama | RPS26 | KAIKKFVIRNIVEAAAVRDIsEAsVFDAyVLPKLYVKLHYC |
| P62854 | S57 | Sugiyama | RPS26 | KKFVIRNIVEAAAVRDIsEAsVFDAyVLPKLYVKLHYCVSC |
| P62857 | S61 | Sugiyama | RPS28 | sIIRNVKGPVREGDVLtLLEsEREARRLR____________ |
| P62857 | T38 | Sugiyama | RPS28 | LGRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtL |
| P62857 | T57 | Sugiyama | RPS28 | DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________ |
| P62899 | S15 | Sugiyama | RPL31 | ______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG |
| P62899 | T107 | Sugiyama | RPL31 | RLSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN__ |
| P62899 | T112 | Sugiyama | RPL31 | RNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN_______ |
| P62899 | T113 | Sugiyama | RPL31 | NEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN________ |
| P62899 | T119 | Sugiyama | RPL31 | PNKLytLVtyVPVttFKNLQtVNVDEN______________ |
| P62899 | T22 | Sugiyama | RPL31 | APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA |
| P62899 | T26 | Sugiyama | RPL31 | KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL |
| P62899 | Y103 | Sugiyama | RPL31 | RIRVRLSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVD |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | S138 | Sugiyama | RPL8 | EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62937 | T157 | Sugiyama | PPIA CYPA | NIVEAMERFGsRNGKTSKKItIADCGQLE____________ |
| P62979 | S123 | Sugiyama | RPS27A UBA80 UBCEP1 | LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK |
| P62979 | S134 | Sugiyama | RPS27A UBA80 UBCEP1 | IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | T30 | Sugiyama | YWHAZ | AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN |
| P63167 | S14 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | _______MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNI |
| P63167 | S21 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAH |
| P63167 | T26 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF |
| P63220 | S68 | Sugiyama | RPS21 | GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____ |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S239 | Sugiyama | ACTG1 ACTG | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S365 | Sugiyama | ACTG1 ACTG | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | S60 | Sugiyama | ACTG1 ACTG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P63261 | T202 | Sugiyama | ACTG1 ACTG | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P63261 | T203 | Sugiyama | ACTG1 ACTG | RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF |
| P63261 | T318 | Sugiyama | ACTG1 ACTG | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P63261 | Y53 | Sugiyama | ACTG1 ACTG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P63267 | S240 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | S61 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P63267 | T319 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P63267 | Y54 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P67809 | S102 | Sugiyama | YBX1 NSEP1 YB1 | EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA |
| P67809 | T108 | Sugiyama | YBX1 NSEP1 YB1 | QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP |
| P68032 | S241 | Sugiyama | ACTC1 ACTC | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | S62 | Sugiyama | ACTC1 ACTC | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68032 | T320 | Sugiyama | ACTC1 ACTC | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68032 | Y55 | Sugiyama | ACTC1 ACTC | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68133 | S241 | Sugiyama | ACTA1 ACTA | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | S62 | Sugiyama | ACTA1 ACTA | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68133 | T320 | Sugiyama | ACTA1 ACTA | VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68133 | Y55 | Sugiyama | ACTA1 ACTA | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68363 | S287 | Sugiyama | TUBA1B | FPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDP |
| P68363 | S439 | Sugiyama | TUBA1B | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | S54 | Sugiyama | TUBA1B | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P68363 | T292 | Sugiyama | TUBA1B | yAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDPRHGKy |
| P68363 | T41 | Sugiyama | TUBA1B | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T80 | Sugiyama | TUBA1B | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| P68363 | T82 | Sugiyama | TUBA1B | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| P68363 | Y282 | Sugiyama | TUBA1B | yPRIHFPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQM |
| P68363 | Y83 | Sugiyama | TUBA1B | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| P68366 | S287 | Sugiyama | TUBA4A TUBA1 | FPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDP |
| P68366 | T292 | Sugiyama | TUBA4A TUBA1 | yAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDPRHGKy |
| P68366 | Y282 | Sugiyama | TUBA4A TUBA1 | yPRIHFPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQM |
| P78371 | S143 | Sugiyama | CCT2 99D8.1 CCTB | PQTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIA |
| P80303 | S257 | Sugiyama | NUCB2 NEFA | DGLDPNDFDPKtFFKLHDVNsDGFLDEQELEALFtKELEKV |
| P80303 | T236 | Sugiyama | NUCB2 NEFA | NHPKVNHPGSKDQLKEVWEEtDGLDPNDFDPKtFFKLHDVN |
| P80303 | T248 | Sugiyama | NUCB2 NEFA | QLKEVWEEtDGLDPNDFDPKtFFKLHDVNsDGFLDEQELEA |
| P80303 | T271 | Sugiyama | NUCB2 NEFA | KLHDVNsDGFLDEQELEALFtKELEKVYDPKNEEDDMVEME |
| P80723 | S219 | Sugiyama | BASP1 NAP22 | AQGPAAsAEEPKPVEAPAANsDQtVtVKE____________ |
| P80723 | T222 | Sugiyama | BASP1 NAP22 | PAAsAEEPKPVEAPAANsDQtVtVKE_______________ |
| P80723 | T224 | Sugiyama | BASP1 NAP22 | AsAEEPKPVEAPAANsDQtVtVKE_________________ |
| P83731 | S86 | Sugiyama | RPL24 | EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE |
| P83731 | T83 | Sugiyama | RPL24 | QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA |
| P84098 | S12 | Sugiyama | RPL19 | _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI |
| P84098 | S37 | Sugiyama | RPL19 | CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV |
| P84098 | T29 | Sugiyama | RPL19 | RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL |
| Q00610 | T875 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | LKLLLPWLEARIHEGCEEPAtHNALAKIyIDsNNNPERFLR |
| Q01082 | S1441 | Sugiyama | SPTBN1 SPTB2 | KQQMLENQMEVRKKEIEELQsQAQALsQEGKSTDEVDSKRL |
| Q01105 | S165 | Sugiyama | SET | PyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQ |
| Q01105 | S166 | Sugiyama | SET | yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT |
| Q01546 | S196 | Sugiyama | KRT76 KRT2B KRT2P | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE |
| Q02790 | S11 | Sugiyama | FKBP4 FKBP52 | __________MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDE |
| Q02790 | S15 | Sugiyama | FKBP4 FKBP52 | ______MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDEGVLK |
| Q02952 | S885 | Sugiyama | AKAP12 AKAP250 | AQKSAEQPEQKAATEVSKELsEsQVHMMAAAVADGTRAATI |
| Q02952 | S887 | Sugiyama | AKAP12 AKAP250 | KSAEQPEQKAATEVSKELsEsQVHMMAAAVADGTRAATIIE |
| Q02952 | T949 | Sugiyama | AKAP12 AKAP250 | AALLTEEVLEREVIAEEEPPtVtEPLPENREARGDTVVSEA |
| Q02952 | T951 | Sugiyama | AKAP12 AKAP250 | LLTEEVLEREVIAEEEPPtVtEPLPENREARGDTVVSEAEL |
| Q05682 | S129 | Sugiyama | CALD1 CAD CDM | KRLQEALERQKEFDPtItDAsLsLPsRRMQNDTAENETTEK |
| Q05682 | T124 | Sugiyama | CALD1 CAD CDM | EERRQKRLQEALERQKEFDPtItDAsLsLPsRRMQNDTAEN |
| Q05682 | T126 | Sugiyama | CALD1 CAD CDM | RRQKRLQEALERQKEFDPtItDAsLsLPsRRMQNDTAENET |
| Q06830 | S30 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | HPAPNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTF |
| Q06830 | S32 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | APNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTFVC |
| Q06830 | T143 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF |
| Q07021 | S201 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | ALVLDCHyPEDEVGQEDEAEsDIFsIREVsFQstGESEWKD |
| Q07021 | S205 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | DCHyPEDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYT |
| Q09161 | S33 | Sugiyama | NCBP1 CBP80 NCBP | GQPHKRRKtsDANEtEDHLEsLICKVGEKSACSLESNLEGL |
| Q12874 | S482 | Sugiyama | SF3A3 SAP61 | LKLQKASERWQPDtEEEyEDssGNVVNKKTYEDLKRQGLL_ |
| Q13033 | T293 | Sugiyama | STRN3 GS2NA SG2NA | KDKHRMNKHKIGNEGLAADLtDDPDtEEALKEFDFLVTAED |
| Q13033 | T298 | Sugiyama | STRN3 GS2NA SG2NA | MNKHKIGNEGLAADLtDDPDtEEALKEFDFLVTAEDGEGAG |
| Q13263 | S512 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | RLDLDLtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATG |
| Q13263 | S784 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK |
| Q13263 | T513 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | LDLDLtADsQPPVFKVFPGsttEDyNLIVIERGAAAAATGQ |
| Q13371 | S25 | Sugiyama | PDCL PHLOP1 PhLP1 | DDKLLGEKLQyyysssEDEDsDHEDKDRGRCAPAsssVPAE |
| Q13428 | S279 | Sugiyama | TCOF1 | PAKRAKKPEEEsEssEEGsEsEEEAPAGTRSQVKASEKILQ |
| Q13428 | S85 | Sugiyama | TCOF1 | AEEDAALQAKKTRVsDPIstsEssEEEEEAEAETAKAtPRL |
| Q13428 | S87 | Sugiyama | TCOF1 | EDAALQAKKTRVsDPIstsEssEEEEEAEAETAKAtPRLAs |
| Q13428 | S88 | Sugiyama | TCOF1 | DAALQAKKTRVsDPIstsEssEEEEEAEAETAKAtPRLAst |
| Q13442 | S176 | Sugiyama | PDAP1 HASPP28 | KKEEERKAKDDATLsGKRMQsLsLNK_______________ |
| Q13442 | S178 | Sugiyama | PDAP1 HASPP28 | EEERKAKDDATLsGKRMQsLsLNK_________________ |
| Q13442 | S63 | Sugiyama | PDAP1 HASPP28 | GGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGVEGLIDI |
| Q13451 | S27 | Sugiyama | FKBP5 AIG6 FKBP51 | AKNNEEsPtAtVAEQGEDITsKKDRGVLKIVKRVGNGEEtP |
| Q13451 | T17 | Sugiyama | FKBP5 AIG6 FKBP51 | ____MttDEGAKNNEEsPtAtVAEQGEDITsKKDRGVLKIV |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13509 | S168 | Sugiyama | TUBB3 TUBB4 | GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS |
| Q13509 | T107 | Sugiyama | TUBB3 TUBB4 | PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC |
| Q13509 | T166 | Sugiyama | TUBB3 TUBB4 | GMGTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT |
| Q13509 | Y106 | Sugiyama | TUBB3 TUBB4 | RPDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECEN |
| Q13541 | S112 | Sugiyama | EIF4EBP1 | EAsQsHLRNsPEDKRAGGEEsQFEMDI______________ |
| Q13765 | S132 | Sugiyama | NACA HSD48 | YKSPAsDtyIVFGEAKIEDLsQQAQLAAAEKFKVQGEAVsN |
| Q13765 | S186 | Sugiyama | NACA HSD48 | sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI |
| Q13765 | S191 | Sugiyama | NACA HSD48 | VDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDIVNAIM |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q13885 | S275 | iPTMNet | TUBB2A TUBB2 | VNMVPFPRLHFFMPGFAPLtsRGsQQyRALTVPELTQQMFD |
| Q13885 | T107 | Sugiyama | TUBB2A TUBB2 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q13885 | Y106 | Sugiyama | TUBB2A TUBB2 | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES |
| Q14152 | S1188 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PWRPLVKPGGWREKEKAREEsWGPPRESRPsEEREWDREKE |
| Q14152 | S907 | Sugiyama | EIF3A EIF3S10 KIAA0139 | DSRWGDRDsEGtWRKGPEADsEWRRGPPEKEWRRGEGRDED |
| Q14152 | S988 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN |
| Q14203 | S417 | Sugiyama | DCTN1 | KKNQELEVVRQQRERLQEELsQAEstIDELKEQVDAALGAE |
| Q14203 | S421 | Sugiyama | DCTN1 | ELEVVRQQRERLQEELsQAEstIDELKEQVDAALGAEEMVE |
| Q14247 | S277 | Sugiyama | CTTN EMS1 | QLHEsQKDyKTGFGGKFGVQsERQDsAAVGFDyKEKLAKHE |
| Q14247 | S282 | Sugiyama | CTTN EMS1 | QKDyKTGFGGKFGVQsERQDsAAVGFDyKEKLAKHEsQQDy |
| Q14247 | T328 | Sugiyama | CTTN EMS1 | GKyGVQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKts |
| Q14257 | S146 | Sugiyama | RCN2 ERC55 | MyDRVIDFDENtALDDAEEEsFRKLHLKDKKRFEKANQDSG |
| Q14257 | S207 | Sugiyama | RCN2 ERC55 | TEFVIQEALEEHDKNGDGFVsLEEFLGDyRWDPTANEDPEW |
| Q14257 | S284 | Sugiyama | RCN2 ERC55 | AQEEALHLIDEMDLNGDKKLsEEEILENPDLFLtsEAtDyG |
| Q14257 | S298 | Sugiyama | RCN2 ERC55 | NGDKKLsEEEILENPDLFLtsEAtDyGRQLHDDyFyHDEL_ |
| Q14257 | T137 | Sugiyama | RCN2 ERC55 | VTWDEyNIQMyDRVIDFDENtALDDAEEEsFRKLHLKDKKR |
| Q14257 | T297 | Sugiyama | RCN2 ERC55 | LNGDKKLsEEEILENPDLFLtsEAtDyGRQLHDDyFyHDEL |
| Q14257 | T301 | Sugiyama | RCN2 ERC55 | KKLsEEEILENPDLFLtsEAtDyGRQLHDDyFyHDEL____ |
| Q14444 | S97 | Sugiyama | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 | DYQERMNKGERLNQDQLDAVsKyQEVtNNLEFAKELQRsFM |
| Q14568 | S50 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14671 | S183 | Sugiyama | PUM1 KIAA0099 PUMH1 | PKGIFLGDQWRDsAWGTsDHsVsQPIMVQRRPGQsFHVNsE |
| Q14978 | S637 | Sugiyama | NOLC1 KIAA0035 NS5ATP13 | GEKRAssPFRRVREEEIEVDsRVADNsFDAKRGAAGDWGER |
| Q14978 | S643 | Sugiyama | NOLC1 KIAA0035 NS5ATP13 | sPFRRVREEEIEVDsRVADNsFDAKRGAAGDWGERANQVLK |
| Q14980 | S1317 | Sugiyama | NUMA1 NMP22 NUMA | LREEAEKQRVASENLRQELTsQAERAEELGQELKAWQEKFF |
| Q14CN4 | S138 | Sugiyama | KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 | IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN |
| Q15056 | S110 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK |
| Q15084 | S230 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | QTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIFQKGEsPV |
| Q15084 | S428 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | EREPWDGRDGELPVEDDIDLsDVELDDLGKDEL________ |
| Q15084 | T223 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | AAsEVKEQTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIF |
| Q15181 | S127 | Sugiyama | PPA1 IOPPP PP | NDKHTGCCGDNDPIDVCEIGsKVCARGEIIGVKVLGILAMI |
| Q15185 | S118 | Sugiyama | PTGES3 P23 TEBP | WLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGDEDVDL |
| Q15293 | S69 | Sugiyama | RCN1 RCN | PPEDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVD |
| Q15293 | T101 | Sugiyama | RCN1 RCN | KERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNVA |
| Q15293 | T71 | Sugiyama | RCN1 RCN | EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI |
| Q15365 | S50 | Sugiyama | PCBP1 | GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK |
| Q15366 | S50 | Sugiyama | PCBP2 | GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK |
| Q15642 | S288 | Sugiyama | TRIP10 CIP4 STOT STP | LIELHKSGFARPGDVEFEDFsQPMNRAPsDssLGtPsDGRP |
| Q15785 | S51 | Sugiyama | TOMM34 URCC3 | LyGRALRVLQAQGssDPEEEsVLysNRAACHLKDGNCRDCI |
| Q15785 | S55 | Sugiyama | TOMM34 URCC3 | ALRVLQAQGssDPEEEsVLysNRAACHLKDGNCRDCIKDCT |
| Q16513 | S952 | Sugiyama | PKN2 PRK2 PRKCL2 | PFIPTIRGREDVSNFDDEFtsEAPILtPPREPRILsEEEQE |
| Q16513 | T958 | Sugiyama | PKN2 PRK2 PRKCL2 | RGREDVSNFDDEFtsEAPILtPPREPRILsEEEQEMFRDFD |
| Q16576 | T10 | Sugiyama | RBBP7 RBAP46 | ___________MAsKEMFEDtVEERVINEEYKIWKKNTPFL |
| Q2TAA2 | S241 | Sugiyama | IAH1 | SSLPLLLPYWRDVAEAKPELsLLGDGDH_____________ |
| Q3SY84 | S143 | Sugiyama | KRT71 K6IRS1 KB34 KRT6IRS1 | IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q562R1 | S240 | Sugiyama | ACTBL2 | VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE |
| Q58FF6 | T165 | Sugiyama | HSP90AB4P | DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | S405 | Sugiyama | HSP90AB3P HSP90BC | YMTEPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK |
| Q58FF7 | S408 | Sugiyama | HSP90AB3P HSP90BC | EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| Q58FF7 | T169 | Sugiyama | HSP90AB3P HSP90BC | DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG |
| Q58FF7 | T410 | Sugiyama | HSP90AB3P HSP90BC | IDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK |
| Q58FF8 | S308 | Sugiyama | HSP90AB2P HSP90BB | YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE |
| Q58FG1 | T28 | Sugiyama | HSP90AA4P HSP90AD HSPCAL2 | SKLDSGKEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLG |
| Q58FG1 | T30 | Sugiyama | HSP90AA4P HSP90AD HSPCAL2 | LDSGKEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLGTI |
| Q5H9R7 | S617 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | NIALFEACCKERIQQFDDGGsDEEDIWEEKHIAFtPEsQRR |
| Q5QNW6 | S39 | Sugiyama | H2BC18 HIST2H2BF | VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q5TCY1 | T184 | Sugiyama | TTBK1 BDTK KIAA1855 | RLPSTYRKCYMLDFGLARQYtNTTGDVRPPRNVAGFRGTVR |
| Q5XKE5 | S155 | Sugiyama | KRT79 K6L KB38 KRT6L | IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| Q6IBS0 | S140 | Sugiyama | TWF2 PTK9L MSTP011 | ELFGTVKDDLSFAGyQKHLssCAAPAPLtsAERELQQIRIN |
| Q6P996 | S779 | Sugiyama | PDXDC1 KIAA0251 | QHtDQtEAFQKGVPHPEDDHsQVEGPEsLR___________ |
| Q6PEY2 | S287 | Sugiyama | TUBA3E | FPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDP |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | S54 | Sugiyama | TUBA3E | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q6PEY2 | T292 | Sugiyama | TUBA3E | yAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDPRHGKY |
| Q6PEY2 | T41 | Sugiyama | TUBA3E | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q6PEY2 | Y282 | Sugiyama | TUBA3E | yPRIHFPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQM |
| Q6S8J3 | S1065 | Sugiyama | POTEE A26C1A POTE2 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | S939 | Sugiyama | POTEE A26C1A POTE2 | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| Q6UXH1 | S295 | Sugiyama | CRELD2 UNQ185/PRO211 | KECISGYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSY |
| Q6UXH1 | T300 | Sugiyama | CRELD2 UNQ185/PRO211 | GYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSYVCVCP |
| Q6YN16 | T56 | Sugiyama | HSDL2 C9orf99 SDR13C1 | NIVIAAKTAQPHPKLLGtIYtAAEEIEAVGGKALPCIVDVR |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71U36 | S287 | Sugiyama | TUBA1A TUBA3 | FPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDP |
| Q71U36 | S439 | Sugiyama | TUBA1A TUBA3 | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | S54 | Sugiyama | TUBA1A TUBA3 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q71U36 | T292 | Sugiyama | TUBA1A TUBA3 | yAPVIsAEKAyHEQLsVAEItNACFEPANQMVKCDPRHGKy |
| Q71U36 | T41 | Sugiyama | TUBA1A TUBA3 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T80 | Sugiyama | TUBA1A TUBA3 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q71U36 | T82 | Sugiyama | TUBA1A TUBA3 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q71U36 | Y282 | Sugiyama | TUBA1A TUBA3 | yPRIHFPLAtyAPVIsAEKAyHEQLsVAEItNACFEPANQM |
| Q71U36 | Y83 | Sugiyama | TUBA1A TUBA3 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q7KZF4 | S126 | Sugiyama | SND1 TDRD11 | GREyGMIyLGKDTNGENIAEsLVAEGLAtRREGMRANNPEQ |
| Q7KZF4 | T134 | Sugiyama | SND1 TDRD11 | LGKDTNGENIAEsLVAEGLAtRREGMRANNPEQNRLsECEE |
| Q7RTS7 | S153 | Sugiyama | KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 | IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE |
| Q7Z794 | S177 | Sugiyama | KRT77 KRT1B | IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| Q86UE4 | T477 | Sugiyama | MTDH AEG1 LYRIC | stAQDtEELEKEIREDLPVNtsKTRPKQEKAFSLKtIstsD |
| Q86V81 | S145 | Sugiyama | ALYREF ALY BEF THOC4 | LFAEFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQ |
| Q86V81 | S8 | Sugiyama | ALYREF ALY BEF THOC4 | _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG |
| Q86Y46 | S145 | Sugiyama | KRT73 K6IRS3 KB36 KRT6IRS3 | IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q8IWI9 | S863 | Sugiyama | MGA KIAA0518 MAD5 | GFSSNAPTSPVVYQLPTKStsyVRtLDsVLKKQSTISPSTS |
| Q8IWI9 | S870 | Sugiyama | MGA KIAA0518 MAD5 | TSPVVYQLPTKStsyVRtLDsVLKKQSTISPSTSYSLKPHS |
| Q8IWI9 | T862 | Sugiyama | MGA KIAA0518 MAD5 | MGFSSNAPTSPVVYQLPTKStsyVRtLDsVLKKQSTISPST |
| Q8IWI9 | T867 | Sugiyama | MGA KIAA0518 MAD5 | NAPTSPVVYQLPTKStsyVRtLDsVLKKQSTISPSTSYSLK |
| Q8IWI9 | Y864 | Sugiyama | MGA KIAA0518 MAD5 | FSSNAPTSPVVYQLPTKStsyVRtLDsVLKKQSTISPSTSY |
| Q8IWZ3 | S180 | Sugiyama | ANKHD1 KIAA1085 MASK VBARP PP2500 | TADGKAFADPEVLRRLtssVsCALDEAAAALTRMKAENsHN |
| Q8IYB3 | S874 | Sugiyama | SRRM1 SRM160 | tttLAQEEPVAAPEPKKEtEsEAEDNLDDLEKHLREKALRS |
| Q8IYB3 | T872 | Sugiyama | SRRM1 SRM160 | AAtttLAQEEPVAAPEPKKEtEsEAEDNLDDLEKHLREKAL |
| Q8N3X1 | S124 | Sugiyama | FNBP4 FBP30 KIAA1014 | tGGLCLLGAyADsDDDDNDVsEKLAQSKETNGNQSTDIDST |
| Q8N6T3 | S174 | Sugiyama | ARFGAP1 ARF1GAP | QsVtAssDKAFEDWLNDDLGsyQGAQGNRyVGFGNtPPPQK |
| Q8NBS9 | S426 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | KKVSEHSGGRDLDSLHRFVLsQAKDEL______________ |
| Q8NE71 | S595 | Sugiyama | ABCF1 ABC50 | TKEALTRKQQKCRRKNQDEEsQEAPELLKRPKEYTVRFTFP |
| Q8NFI4 | S218 | Sugiyama | ST13P5 FAM10A5 | WEEAAHDLAFACKLDyDEDAsAMLKEVQPRAQKIAEHWRKY |
| Q8NHG7 | S46 | Sugiyama | SVIP | AEAAERRQKEAASRGILDVQsVQEKRKKKEKIEKQIATsGP |
| Q8TAM6 | S280 | Sugiyama | ERMN KIAA1189 | TISYRKIRKGNTKQRIDEFEsMMHL________________ |
| Q8WU90 | S231 | Sugiyama | ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 | LPPGFVLKKDKKKEEKEDEIsLEDLIERERSALGPNVTKIT |
| Q8WUM4 | T464 | Sugiyama | PDCD6IP AIP1 ALIX KIAA1375 | LQRNREILDEsLRLLDEEEAtDNDLRAKFKERWQRtPSNEL |
| Q8WX92 | S542 | Sugiyama | NELFB COBRA1 KIAA1182 | ALQKALEPTGQSGEAVKELysQLGEKLEQLDHRKPsPAQAA |
| Q92688 | S117 | Sugiyama | ANP32B APRIL PHAPI2 | GNKLKDIstLEPLKKLECLKsLDLFNCEVtNLNDyREsVFK |
| Q92688 | T126 | Sugiyama | ANP32B APRIL PHAPI2 | LEPLKKLECLKsLDLFNCEVtNLNDyREsVFKLLPQLTYLD |
| Q92769 | S422 | Sugiyama | HDAC2 | PDKRIsIRAsDKRIACDEEFsDsEDEGEGGRRNVADHKKGA |
| Q92973 | S339 | Sugiyama | TNPO1 KPNB2 MIP1 TRN | SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE |
| Q92973 | T335 | Sugiyama | TNPO1 KPNB2 MIP1 TRN | GMKySDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQ |
| Q93079 | S39 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q96A49 | S313 | Sugiyama | SYAP1 PRO3113 | EMEQLVLDKKQEEtAVLEEDsADWEKELQQELQEyEVVtES |
| Q96A49 | T306 | Sugiyama | SYAP1 PRO3113 | NQEDLRKEMEQLVLDKKQEEtAVLEEDsADWEKELQQELQE |
| Q96CT7 | S155 | Sugiyama | CCDC124 | RVLEEGsVEARTIEDAIAVLsVAEEAADRHPERRMRAAFTA |
| Q96EV2 | S215 | Sugiyama | RBM33 PRR8 | LELQKDIKEEsDEEEEDDEEsGRLRFKTERKEGTIIRLsDV |
| Q96HE7 | S143 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD |
| Q96HE7 | T148 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA |
| Q96MH2 | S194 | Sugiyama | HEXIM2 L3 | EAGDSDGRGRAHGEFQRKDFsEtYERFHTESLQGRSKQELV |
| Q96MH2 | T196 | Sugiyama | HEXIM2 L3 | GDSDGRGRAHGEFQRKDFsEtYERFHTESLQGRSKQELVRD |
| Q96PZ0 | T110 | Sugiyama | PUS7 KIAA1897 | sEECEEEESESFADMMKHGLtEADVGItKFVSSHQGFSGIL |
| Q96PZ0 | T117 | Sugiyama | PUS7 KIAA1897 | ESESFADMMKHGLtEADVGItKFVSSHQGFSGILKERysDF |
| Q96ST2 | S554 | Sugiyama | IWS1 IWS1L | QRKKSMSGKRRRNRDGGtFIsDADDVVsAMIVKMNEAAEED |
| Q96ST2 | S561 | Sugiyama | IWS1 IWS1L | GKRRRNRDGGtFIsDADDVVsAMIVKMNEAAEEDRQLNNQK |
| Q96ST2 | T551 | Sugiyama | IWS1 IWS1L | MMLQRKKSMSGKRRRNRDGGtFIsDADDVVsAMIVKMNEAA |
| Q99497 | S57 | Sugiyama | PARK7 | GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q99700 | S451 | Sugiyama | ATXN2 ATX2 SCA2 TNRC13 | sEEFLKREARANQLAEEIESsAQyKARVALENDDRsEEEKy |
| Q99700 | Y454 | Sugiyama | ATXN2 ATX2 SCA2 TNRC13 | FLKREARANQLAEEIESsAQyKARVALENDDRsEEEKyTAV |
| Q99733 | S121 | Sugiyama | NAP1L4 NAP2 | PLFDKRREFItGDVEPtDAEsEWHsENEEEEKLAGDMKSKV |
| Q99733 | S22 | Sugiyama | NAP1L4 NAP2 | ADHsFsDGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQ |
| Q99733 | T28 | Sugiyama | NAP1L4 NAP2 | DGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQERLDNV |
| Q99798 | S79 | Sugiyama | ACO2 | LNRPLTLSEKIVyGHLDDPAsQEIERGKSYLRLRPDRVAMQ |
| Q99832 | T351 | Sugiyama | CCT7 CCTH NIP7-1 | QtSVNALSADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCt |
| Q99848 | S270 | Sugiyama | EBNA1BP2 EBP2 | FGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPGKKGSN |
| Q99877 | S39 | Sugiyama | H2BC15 H2BFD HIST1H2BN | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99879 | S39 | Sugiyama | H2BC14 H2BFE HIST1H2BM | INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99880 | S39 | Sugiyama | H2BC13 H2BFC HIST1H2BL | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q9BQE3 | S439 | Sugiyama | TUBA1C TUBA6 | SEAREDMAALEKDyEEVGADsADGEDEGEEy__________ |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | S54 | Sugiyama | TUBA1C TUBA6 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q9BQE3 | T41 | Sugiyama | TUBA1C TUBA6 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T80 | Sugiyama | TUBA1C TUBA6 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q9BQE3 | T82 | Sugiyama | TUBA1C TUBA6 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q9BQE3 | Y83 | Sugiyama | TUBA1C TUBA6 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q9BSC4 | S548 | Sugiyama | NOL10 | ELREKEEEEEPEGKPsDAEssEssDDEKAWVEEVRKQRRLL |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BVA1 | T107 | Sugiyama | TUBB2B | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q9BVA1 | Y106 | Sugiyama | TUBB2B | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES |
| Q9BW91 | S343 | Sugiyama | NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771 | SHSQFIKLVAEKRDAHWSEDsEADCHAL_____________ |
| Q9BY44 | S524 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | DKsPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKL |
| Q9BY44 | S526 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | sPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKLKA |
| Q9BYX7 | S239 | Sugiyama | POTEKP ACTBL3 FKSG30 | VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE |
| Q9BYX7 | S365 | Sugiyama | POTEKP ACTBL3 FKSG30 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BZI7 | S166 | Sugiyama | UPF3B RENT3B UPF3X | KRDTKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIE |
| Q9BZI7 | T169 | Sugiyama | UPF3B RENT3B UPF3X | TKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIEAKN |
| Q9C0C2 | S1046 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | GLFsPstAHVPDGALGQRDQssWQNsDAsQEVGGHQERQQA |
| Q9C0C2 | S1248 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | tsDVNVKSKDLAEVGEGGGHsQAREsGVGQtDWsGVEAGEF |
| Q9C0C2 | S1371 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | QNVELFGAPSEAREHGVGGVsQCPEPGLRHNGsLsPGLEAR |
| Q9H1E3 | S113 | Sugiyama | NUCKS1 NUCKS JC7 | RQAASKAASKQREMLMEDVGsEEEQEEEDEAPFQEKDsGsD |
| Q9H1E3 | S144 | Sugiyama | NUCKS1 NUCKS JC7 | PFQEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPER |
| Q9H2K8 | S331 | Sugiyama | TAOK3 DPK JIK KDS MAP3K18 | ILFQETRNGPLNEsQEDEEDsEHGTsLNREMDSLGSNHSIP |
| Q9H2U2 | S309 | Sugiyama | PPA2 HSPC124 | NCTNVQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVW |
| Q9H2U2 | S313 | Sugiyama | PPA2 HSPC124 | VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG |
| Q9H3N1 | S247 | Sugiyama | TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 | EsAQPLKKVEEEQEADEEDVsEEEAEsKEGtNKDFPQNAIR |
| Q9H6Y2 | S21 | Sugiyama | WDR55 | MDRTCEERPAEDGsDEEDPDsMEAPTRIRDtPEDIVLEAPA |
| Q9NQ39 | S157 | Sugiyama | RPS10P5 RPS10L | TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_ |
| Q9NQ39 | T159 | Sugiyama | RPS10P5 RPS10L | RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___ |
| Q9NQP4 | S103 | Sugiyama | PFDN4 PFD4 | TQEMLEEAKKNLQEEIDALEsRVEsIQRVLADLKVQLYAKF |
| Q9NR28 | S230 | Sugiyama | DIABLO SMAC | EAQIEELRQKTQEEGEERAEsEQEAyLRED___________ |
| Q9NRX4 | T119 | Sugiyama | PHPT1 PHP14 CGI-202 HSPC141 | PAQHAISTEKIKAKyPDyEVtWANDGy______________ |
| Q9NSB2 | S178 | Sugiyama | KRT84 KRTHB4 | AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS |
| Q9NX55 | S104 | Sugiyama | HYPK C15orf63 HSPC136 | KEDLELIMTEMEISRAAAERsLREHMGNVVEALIALTN___ |
| Q9NYL9 | S25 | Sugiyama | TMOD3 | FRKDLEKyKDLDEDELLGNLsEtELKQLETVLDDLDPENAL |
| Q9NYL9 | T27 | Sugiyama | TMOD3 | KDLEKyKDLDEDELLGNLsEtELKQLETVLDDLDPENALLP |
| Q9UBC2 | S493 | Sugiyama | EPS15L1 EPS15R | ETQMISsLKTQIQSQESDLKsQEDDLNRAKSELNRLQQEET |
| Q9UFW8 | S164 | Sugiyama | CGGBP1 CGGBP | DQLRRAYLPDGYENENQLLNsQDC_________________ |
| Q9UG63 | T35 | Sugiyama | ABCF2 HUSSY-18 | EAAKARQRPRKGHEENGDVVtEPQVAEKNEANGRETTEVDL |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UI15 | T190 | Sugiyama | TAGLN3 NP25 | GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________ |
| Q9UI15 | Y192 | Sugiyama | TAGLN3 NP25 | NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________ |
| Q9UII2 | S39 | Sugiyama | ATP5IF1 ATPI ATPIF1 | TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF |
| Q9UKK9 | S24 | Sugiyama | NUDT5 NUDIX5 HSPC115 | QEPtEssQNGKQyIISEELIsEGKWVKLEKTTYMDPTGKtR |
| Q9UPQ0 | S299 | Sugiyama | LIMCH1 KIAA1102 | yVPAPLRKKKAEREEYRKsWstAtsPLGGERPFRYGPRtPV |
| Q9UPQ0 | S303 | Sugiyama | LIMCH1 KIAA1102 | PLRKKKAEREEYRKsWstAtsPLGGERPFRYGPRtPVSDDA |
| Q9UPQ0 | T302 | Sugiyama | LIMCH1 KIAA1102 | APLRKKKAEREEYRKsWstAtsPLGGERPFRYGPRtPVSDD |
| Q9UQ80 | T200 | Sugiyama | PA2G4 EBP1 | TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV |
| Q9UQ88 | S265 | Sugiyama | CDK11A CDC2L2 CDC2L3 PITSLREB | APAQKPAQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSA |
| Q9UQ88 | S271 | Sugiyama | CDK11A CDC2L2 CDC2L3 PITSLREB | AQLKEEKMEERDLLsDLQDIsDsERKTSSAESSSAESGSGS |
| Q9Y2B0 | S116 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA |
| Q9Y2B0 | T100 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL |
| Q9Y3B8 | S201 | Sugiyama | REXO2 SFN SMFN CGI-114 | PEEYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDE |
| Q9Y3B8 | S203 | Sugiyama | REXO2 SFN SMFN CGI-114 | EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK |
| Q9Y3T9 | S682 | Sugiyama | NOC2L NIR | KQFKDLFDLNssEEDDtEGFsERGILRPLStRHGVEDDEED |
| Q9Y3T9 | T678 | Sugiyama | NOC2L NIR | DEDRKQFKDLFDLNssEEDDtEGFsERGILRPLStRHGVED |
| Q9Y3U8 | S91 | Sugiyama | RPL36 | KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______ |
| Q9Y5L4 | S81 | Sugiyama | TIMM13 TIM13B TIMM13A TIMM13B | SEQKCIAMCMDRyMDAWNtVsRAYNSRLQRERANM______ |
| Q9Y5S9 | S56 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF |
| Q9Y6W5 | S442 | Sugiyama | WASF2 WAVE2 | DTTKPKSSLPAVSDARSDLLsAIRQGFQLRRVEEQREQEKR |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 4.440892e-16 | 15.353 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 2.231548e-14 | 13.651 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.076916e-13 | 12.968 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 2.774447e-13 | 12.557 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 7.078227e-12 | 11.150 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 6.834311e-12 | 11.165 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.765255e-11 | 10.753 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.550069e-10 | 9.810 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 2.451104e-10 | 9.611 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 2.601714e-10 | 9.585 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.196261e-09 | 8.922 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.435827e-09 | 8.843 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.697852e-09 | 8.770 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 2.821603e-09 | 8.550 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 4.945339e-09 | 8.306 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 7.354140e-09 | 8.133 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.380295e-08 | 7.860 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.266935e-08 | 7.645 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.266935e-08 | 7.645 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 2.667862e-08 | 7.574 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 2.951763e-08 | 7.530 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 3.240402e-08 | 7.489 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 5.072588e-08 | 7.295 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 5.846802e-08 | 7.233 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 6.811884e-08 | 7.167 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 9.557918e-08 | 7.020 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.133962e-07 | 6.945 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.273328e-07 | 6.895 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.583820e-07 | 6.800 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 2.489308e-07 | 6.604 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 2.893100e-07 | 6.539 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 3.595889e-07 | 6.444 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 3.880132e-07 | 6.411 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 4.678974e-07 | 6.330 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 4.915081e-07 | 6.308 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 5.305126e-07 | 6.275 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 6.043809e-07 | 6.219 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 8.006616e-07 | 6.097 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 8.988763e-07 | 6.046 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.136588e-06 | 5.944 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 1.122960e-06 | 5.950 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.536968e-06 | 5.813 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.643080e-06 | 5.784 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.660616e-06 | 5.780 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.736504e-06 | 5.760 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 1.856171e-06 | 5.731 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 2.208478e-06 | 5.656 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 2.208478e-06 | 5.656 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 2.216372e-06 | 5.654 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 2.438312e-06 | 5.613 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.546266e-06 | 5.594 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.374697e-06 | 5.472 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 3.833389e-06 | 5.416 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 3.957601e-06 | 5.403 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 4.549621e-06 | 5.342 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 4.985419e-06 | 5.302 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 5.189735e-06 | 5.285 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 5.163474e-06 | 5.287 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 5.373569e-06 | 5.270 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 5.700517e-06 | 5.244 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 7.973269e-06 | 5.098 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 8.392880e-06 | 5.076 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 8.266913e-06 | 5.083 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 9.314034e-06 | 5.031 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.018201e-05 | 4.992 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.018201e-05 | 4.992 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.121758e-05 | 4.950 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.111573e-05 | 4.954 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 2.005159e-05 | 4.698 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 2.137384e-05 | 4.670 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 2.312280e-05 | 4.636 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 2.299387e-05 | 4.638 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 2.299387e-05 | 4.638 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 2.555181e-05 | 4.593 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.926416e-05 | 4.534 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.926416e-05 | 4.534 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.926416e-05 | 4.534 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 2.707530e-05 | 4.567 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.926416e-05 | 4.534 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 2.864994e-05 | 4.543 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 3.042427e-05 | 4.517 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.525900e-05 | 4.453 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 3.665859e-05 | 4.436 | 0 | 0 |
| Kinesins | R-HSA-983189 | 3.783579e-05 | 4.422 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 3.783579e-05 | 4.422 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 4.000262e-05 | 4.398 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 4.211181e-05 | 4.376 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 4.143142e-05 | 4.383 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 4.143142e-05 | 4.383 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 4.172468e-05 | 4.380 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 4.788878e-05 | 4.320 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 4.829776e-05 | 4.316 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 4.930557e-05 | 4.307 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 5.268671e-05 | 4.278 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 5.438083e-05 | 4.265 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 5.538998e-05 | 4.257 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 5.727828e-05 | 4.242 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 6.428176e-05 | 4.192 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 6.818634e-05 | 4.166 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 6.818634e-05 | 4.166 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 7.045695e-05 | 4.152 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 7.479385e-05 | 4.126 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 7.936909e-05 | 4.100 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 8.152806e-05 | 4.089 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 8.502481e-05 | 4.070 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 8.336162e-05 | 4.079 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 8.393166e-05 | 4.076 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 8.723397e-05 | 4.059 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 9.035186e-05 | 4.044 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 9.799486e-05 | 4.009 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 1.006824e-04 | 3.997 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 1.090368e-04 | 3.962 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 1.185271e-04 | 3.926 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 1.185271e-04 | 3.926 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.153966e-04 | 3.938 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.177417e-04 | 3.929 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.238102e-04 | 3.907 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.323922e-04 | 3.878 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 1.376590e-04 | 3.861 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.377878e-04 | 3.861 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 1.425284e-04 | 3.846 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.330729e-04 | 3.876 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.394279e-04 | 3.856 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.624891e-04 | 3.789 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 1.633993e-04 | 3.787 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 1.633993e-04 | 3.787 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 1.633993e-04 | 3.787 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.693076e-04 | 3.771 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.731750e-04 | 3.762 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 1.840612e-04 | 3.735 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 1.773518e-04 | 3.751 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 1.731750e-04 | 3.762 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.898446e-04 | 3.722 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 2.122243e-04 | 3.673 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 2.164103e-04 | 3.665 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 2.221640e-04 | 3.653 | 0 | 0 |
| Depurination | R-HSA-73927 | 2.238766e-04 | 3.650 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.374973e-04 | 3.624 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 2.396620e-04 | 3.620 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 2.584368e-04 | 3.588 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.633415e-04 | 3.579 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 2.586210e-04 | 3.587 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 2.636832e-04 | 3.579 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 2.636832e-04 | 3.579 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 2.724752e-04 | 3.565 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 2.724752e-04 | 3.565 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 2.803681e-04 | 3.552 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.919317e-04 | 3.535 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 3.008326e-04 | 3.522 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 3.024282e-04 | 3.519 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 3.321995e-04 | 3.479 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 3.650761e-04 | 3.438 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.655718e-04 | 3.437 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 3.364325e-04 | 3.473 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 3.712521e-04 | 3.430 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 3.719147e-04 | 3.430 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.893767e-04 | 3.410 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 4.045198e-04 | 3.393 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 4.045198e-04 | 3.393 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 4.430731e-04 | 3.354 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 4.454346e-04 | 3.351 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 4.243773e-04 | 3.372 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 4.243773e-04 | 3.372 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 4.454346e-04 | 3.351 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 4.174166e-04 | 3.379 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 4.092048e-04 | 3.388 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 4.549857e-04 | 3.342 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 4.567215e-04 | 3.340 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 4.608290e-04 | 3.336 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 4.608290e-04 | 3.336 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 4.821382e-04 | 3.317 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 4.902194e-04 | 3.310 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 5.057696e-04 | 3.296 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 5.480169e-04 | 3.261 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 5.774706e-04 | 3.238 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 5.703527e-04 | 3.244 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 5.215453e-04 | 3.283 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 5.839890e-04 | 3.234 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 6.398201e-04 | 3.194 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 6.784210e-04 | 3.169 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 6.979007e-04 | 3.156 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 7.011467e-04 | 3.154 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 8.192637e-04 | 3.087 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 8.270979e-04 | 3.082 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 8.299130e-04 | 3.081 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 7.574999e-04 | 3.121 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 7.574999e-04 | 3.121 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 8.349363e-04 | 3.078 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 7.548853e-04 | 3.122 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 7.851542e-04 | 3.105 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 8.891892e-04 | 3.051 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 8.891892e-04 | 3.051 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 9.304362e-04 | 3.031 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 9.304362e-04 | 3.031 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.025387e-03 | 2.989 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.061556e-03 | 2.974 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.065062e-03 | 2.973 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.077371e-03 | 2.968 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.102984e-03 | 2.957 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 1.103341e-03 | 2.957 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 1.160713e-03 | 2.935 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.204778e-03 | 2.919 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.237072e-03 | 2.908 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.237072e-03 | 2.908 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.237715e-03 | 2.907 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 1.245668e-03 | 2.905 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 1.245668e-03 | 2.905 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 1.322217e-03 | 2.879 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.395070e-03 | 2.855 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.454228e-03 | 2.837 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.371320e-03 | 2.863 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 1.487449e-03 | 2.828 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.344317e-03 | 2.871 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 1.519281e-03 | 2.818 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 1.454228e-03 | 2.837 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.452515e-03 | 2.838 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.520623e-03 | 2.818 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.525500e-03 | 2.817 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.559104e-03 | 2.807 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 1.559104e-03 | 2.807 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 1.560632e-03 | 2.807 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.616372e-03 | 2.791 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 1.629776e-03 | 2.788 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.712781e-03 | 2.766 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 1.727198e-03 | 2.763 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.782208e-03 | 2.749 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 1.833107e-03 | 2.737 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 1.852837e-03 | 2.732 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.876041e-03 | 2.727 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.911372e-03 | 2.719 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 1.933900e-03 | 2.714 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.934644e-03 | 2.713 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 1.948086e-03 | 2.710 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 1.948086e-03 | 2.710 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 2.043228e-03 | 2.690 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 2.403264e-03 | 2.619 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 2.177105e-03 | 2.662 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 2.286891e-03 | 2.641 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.289940e-03 | 2.640 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.403264e-03 | 2.619 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 2.404168e-03 | 2.619 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 2.326445e-03 | 2.633 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 2.122857e-03 | 2.673 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 2.414225e-03 | 2.617 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 2.444535e-03 | 2.612 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 2.591019e-03 | 2.587 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 2.599566e-03 | 2.585 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 2.713848e-03 | 2.566 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.825917e-03 | 2.549 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.825917e-03 | 2.549 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 2.826762e-03 | 2.549 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 3.016526e-03 | 2.520 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 3.018760e-03 | 2.520 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 3.099798e-03 | 2.509 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 3.113528e-03 | 2.507 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 3.197924e-03 | 2.495 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 3.291370e-03 | 2.483 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 3.318934e-03 | 2.479 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 3.573980e-03 | 2.447 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 3.623269e-03 | 2.441 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 3.628527e-03 | 2.440 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 3.862048e-03 | 2.413 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 3.877062e-03 | 2.411 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 4.066657e-03 | 2.391 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 4.173974e-03 | 2.379 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 4.236400e-03 | 2.373 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 4.272859e-03 | 2.369 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 4.469365e-03 | 2.350 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 4.476733e-03 | 2.349 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 4.531214e-03 | 2.344 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 4.557572e-03 | 2.341 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 4.666824e-03 | 2.331 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 4.745103e-03 | 2.324 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 5.120154e-03 | 2.291 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 5.049980e-03 | 2.297 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 5.285410e-03 | 2.277 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 5.239800e-03 | 2.281 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 5.049980e-03 | 2.297 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 5.859516e-03 | 2.232 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 5.285410e-03 | 2.277 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 5.552276e-03 | 2.256 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 5.393597e-03 | 2.268 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 5.260144e-03 | 2.279 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 6.121173e-03 | 2.213 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 6.149145e-03 | 2.211 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 6.149145e-03 | 2.211 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 6.320931e-03 | 2.199 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 6.320931e-03 | 2.199 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 6.448859e-03 | 2.191 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 6.558653e-03 | 2.183 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 6.581940e-03 | 2.182 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 6.581940e-03 | 2.182 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 6.582652e-03 | 2.182 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 6.727619e-03 | 2.172 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 6.727619e-03 | 2.172 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 6.823224e-03 | 2.166 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 7.077871e-03 | 2.150 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 7.169684e-03 | 2.145 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 7.313952e-03 | 2.136 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 7.394697e-03 | 2.131 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 7.394697e-03 | 2.131 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 7.394697e-03 | 2.131 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 7.394697e-03 | 2.131 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 7.512613e-03 | 2.124 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 7.515416e-03 | 2.124 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 7.515416e-03 | 2.124 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 7.561488e-03 | 2.121 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 7.826103e-03 | 2.106 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 8.133296e-03 | 2.090 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 8.224752e-03 | 2.085 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 8.365565e-03 | 2.078 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 8.408673e-03 | 2.075 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 8.443413e-03 | 2.073 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 8.447474e-03 | 2.073 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 8.447474e-03 | 2.073 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 8.505454e-03 | 2.070 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 8.629936e-03 | 2.064 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 8.629936e-03 | 2.064 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 8.801385e-03 | 2.055 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 8.876121e-03 | 2.052 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.995783e-03 | 2.046 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 9.008261e-03 | 2.045 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 9.031939e-03 | 2.044 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 9.275856e-03 | 2.033 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 9.423847e-03 | 2.026 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 9.424744e-03 | 2.026 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 9.640454e-03 | 2.016 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 9.672856e-03 | 2.014 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 9.825266e-03 | 2.008 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 9.825266e-03 | 2.008 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 9.825266e-03 | 2.008 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 9.771289e-03 | 2.010 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 9.771289e-03 | 2.010 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.062321e-02 | 1.974 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.062321e-02 | 1.974 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 9.715729e-03 | 2.013 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 1.087595e-02 | 1.964 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 9.771289e-03 | 2.010 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.198981e-02 | 1.921 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.062321e-02 | 1.974 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 1.155003e-02 | 1.937 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 1.161751e-02 | 1.935 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.042762e-02 | 1.982 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.161751e-02 | 1.935 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 9.951211e-03 | 2.002 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.062321e-02 | 1.974 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.062321e-02 | 1.974 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.161751e-02 | 1.935 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.214219e-02 | 1.916 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 1.139705e-02 | 1.943 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.224883e-02 | 1.912 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.290761e-02 | 1.889 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 1.290761e-02 | 1.889 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 1.290761e-02 | 1.889 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 1.290761e-02 | 1.889 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.296236e-02 | 1.887 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.300177e-02 | 1.886 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 1.353686e-02 | 1.868 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.357551e-02 | 1.867 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.368460e-02 | 1.864 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.417653e-02 | 1.848 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.452122e-02 | 1.838 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.456707e-02 | 1.837 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 1.459156e-02 | 1.836 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 1.504619e-02 | 1.823 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.517168e-02 | 1.819 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 1.517168e-02 | 1.819 | 0 | 0 |
| Protein folding | R-HSA-391251 | 1.557061e-02 | 1.808 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.594405e-02 | 1.797 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.594405e-02 | 1.797 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.602055e-02 | 1.795 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 1.630585e-02 | 1.788 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.637820e-02 | 1.786 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 1.647227e-02 | 1.783 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 1.647227e-02 | 1.783 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 1.647227e-02 | 1.783 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 1.672145e-02 | 1.777 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 1.687636e-02 | 1.773 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.687636e-02 | 1.773 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.693537e-02 | 1.771 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 1.693537e-02 | 1.771 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.693537e-02 | 1.771 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.693537e-02 | 1.771 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 1.713480e-02 | 1.766 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 1.718041e-02 | 1.765 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 1.733975e-02 | 1.761 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 1.739953e-02 | 1.759 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.812150e-02 | 1.742 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.812150e-02 | 1.742 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.812150e-02 | 1.742 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.812150e-02 | 1.742 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.812150e-02 | 1.742 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 1.863666e-02 | 1.730 | 0 | 0 |
| RSK activation | R-HSA-444257 | 1.863666e-02 | 1.730 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.863666e-02 | 1.730 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 1.863666e-02 | 1.730 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 1.863666e-02 | 1.730 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 1.873147e-02 | 1.727 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.898668e-02 | 1.722 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 1.899685e-02 | 1.721 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 1.899685e-02 | 1.721 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.938527e-02 | 1.713 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.952824e-02 | 1.709 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 2.009782e-02 | 1.697 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.009782e-02 | 1.697 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 2.048765e-02 | 1.689 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 2.048765e-02 | 1.689 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 2.050625e-02 | 1.688 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.056576e-02 | 1.687 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.164193e-02 | 1.665 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.164193e-02 | 1.665 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 2.164193e-02 | 1.665 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 2.246540e-02 | 1.648 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 2.255179e-02 | 1.647 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 2.331072e-02 | 1.632 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 2.333890e-02 | 1.632 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 3.114377e-02 | 1.507 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 3.114377e-02 | 1.507 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 3.114377e-02 | 1.507 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 3.114377e-02 | 1.507 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 3.114377e-02 | 1.507 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 3.114377e-02 | 1.507 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 3.114377e-02 | 1.507 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 3.114377e-02 | 1.507 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 2.515466e-02 | 1.599 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 2.582684e-02 | 1.588 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 2.413441e-02 | 1.617 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 2.413441e-02 | 1.617 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 2.413441e-02 | 1.617 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 2.413441e-02 | 1.617 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 3.106812e-02 | 1.508 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.346481e-02 | 1.630 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 2.346481e-02 | 1.630 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 2.346481e-02 | 1.630 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 2.346481e-02 | 1.630 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 2.346481e-02 | 1.630 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.565328e-02 | 1.591 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 2.582684e-02 | 1.588 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 2.801498e-02 | 1.553 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 2.389200e-02 | 1.622 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 3.009557e-02 | 1.521 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 2.785986e-02 | 1.555 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 3.009651e-02 | 1.521 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.593175e-02 | 1.586 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.426636e-02 | 1.615 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.426636e-02 | 1.615 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 2.870430e-02 | 1.542 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 3.011201e-02 | 1.521 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.953559e-02 | 1.530 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.557129e-02 | 1.592 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 3.148187e-02 | 1.502 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 3.155975e-02 | 1.501 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 3.205743e-02 | 1.494 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 3.205743e-02 | 1.494 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 3.356379e-02 | 1.474 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 3.362137e-02 | 1.473 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 3.451450e-02 | 1.462 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 3.458187e-02 | 1.461 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 3.458187e-02 | 1.461 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 3.507395e-02 | 1.455 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 3.629682e-02 | 1.440 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 3.734902e-02 | 1.428 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 3.737502e-02 | 1.427 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 3.797222e-02 | 1.421 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 3.918646e-02 | 1.407 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 3.918646e-02 | 1.407 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 4.038908e-02 | 1.394 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 4.038908e-02 | 1.394 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 4.117656e-02 | 1.385 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 4.138712e-02 | 1.383 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 4.159375e-02 | 1.381 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 4.274925e-02 | 1.369 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 4.373257e-02 | 1.359 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 4.489165e-02 | 1.348 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 4.497275e-02 | 1.347 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 4.503117e-02 | 1.346 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 4.634156e-02 | 1.334 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 4.864062e-02 | 1.313 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 4.866398e-02 | 1.313 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 4.935259e-02 | 1.307 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 4.935259e-02 | 1.307 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 4.976505e-02 | 1.303 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 4.986542e-02 | 1.302 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 4.986542e-02 | 1.302 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 5.021258e-02 | 1.299 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 5.021258e-02 | 1.299 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 5.021258e-02 | 1.299 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 5.021258e-02 | 1.299 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 5.021258e-02 | 1.299 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 5.021258e-02 | 1.299 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 5.021258e-02 | 1.299 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 5.113841e-02 | 1.291 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 5.118631e-02 | 1.291 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 5.239099e-02 | 1.281 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 5.276124e-02 | 1.278 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 5.362907e-02 | 1.271 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 5.362907e-02 | 1.271 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 5.444963e-02 | 1.264 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 5.641130e-02 | 1.249 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 5.641130e-02 | 1.249 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 5.693141e-02 | 1.245 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 5.703721e-02 | 1.244 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 5.703721e-02 | 1.244 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 5.703721e-02 | 1.244 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 5.703721e-02 | 1.244 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 5.774486e-02 | 1.238 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 5.805433e-02 | 1.236 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 5.871279e-02 | 1.231 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 5.882995e-02 | 1.230 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 5.882995e-02 | 1.230 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 6.111351e-02 | 1.214 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 6.111351e-02 | 1.214 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 6.208475e-02 | 1.207 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 6.209974e-02 | 1.207 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 6.209974e-02 | 1.207 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 6.254060e-02 | 1.204 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.298228e-02 | 1.201 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 6.347632e-02 | 1.197 | 0 | 0 |
| Nef mediated downregulation of CD28 cell surface expression | R-HSA-164939 | 6.414984e-02 | 1.193 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 6.414984e-02 | 1.193 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 6.414984e-02 | 1.193 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 6.414984e-02 | 1.193 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 6.414984e-02 | 1.193 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 6.414984e-02 | 1.193 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 6.414984e-02 | 1.193 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 6.525883e-02 | 1.185 | 0 | 0 |
| IRS activation | R-HSA-74713 | 7.233279e-02 | 1.141 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 7.233279e-02 | 1.141 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 7.233279e-02 | 1.141 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 7.233279e-02 | 1.141 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 7.233279e-02 | 1.141 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 9.802627e-02 | 1.009 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 9.802627e-02 | 1.009 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 9.802627e-02 | 1.009 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 9.802627e-02 | 1.009 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 9.802627e-02 | 1.009 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 9.802627e-02 | 1.009 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 6.584727e-02 | 1.181 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 8.416502e-02 | 1.075 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 8.416502e-02 | 1.075 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 7.078063e-02 | 1.150 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 7.078063e-02 | 1.150 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 7.078063e-02 | 1.150 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 7.078063e-02 | 1.150 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 7.078063e-02 | 1.150 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 7.078063e-02 | 1.150 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 7.078063e-02 | 1.150 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 7.078063e-02 | 1.150 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 8.617791e-02 | 1.065 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 7.104622e-02 | 1.148 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 7.104622e-02 | 1.148 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 6.909520e-02 | 1.161 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 8.050560e-02 | 1.094 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 6.606670e-02 | 1.180 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 9.293901e-02 | 1.032 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 9.293901e-02 | 1.032 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 8.690536e-02 | 1.061 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 8.690536e-02 | 1.061 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 7.512582e-02 | 1.124 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 9.119288e-02 | 1.040 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 6.621887e-02 | 1.179 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 7.627842e-02 | 1.118 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 7.627842e-02 | 1.118 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 8.686468e-02 | 1.061 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 6.964551e-02 | 1.157 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 7.627842e-02 | 1.118 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 8.811352e-02 | 1.055 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 7.104622e-02 | 1.148 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 6.606670e-02 | 1.180 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 9.119288e-02 | 1.040 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 7.874398e-02 | 1.104 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 6.584727e-02 | 1.181 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 8.617791e-02 | 1.065 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 9.657617e-02 | 1.015 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 6.584727e-02 | 1.181 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 6.666036e-02 | 1.176 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 7.646991e-02 | 1.117 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 7.078063e-02 | 1.150 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 8.050560e-02 | 1.094 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 7.512582e-02 | 1.124 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.712326e-02 | 1.173 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 9.252710e-02 | 1.034 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 9.802627e-02 | 1.009 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 9.616495e-02 | 1.017 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 7.605696e-02 | 1.119 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 9.119288e-02 | 1.040 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 7.078063e-02 | 1.150 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.582391e-02 | 1.019 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.582391e-02 | 1.019 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 9.802627e-02 | 1.009 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 6.551420e-02 | 1.184 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 8.901384e-02 | 1.051 | 0 | 0 |
| Immune System | R-HSA-168256 | 7.176997e-02 | 1.144 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 6.584727e-02 | 1.181 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 7.312776e-02 | 1.136 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 7.109062e-02 | 1.148 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 7.233279e-02 | 1.141 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 9.802627e-02 | 1.009 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 9.802627e-02 | 1.009 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 8.416502e-02 | 1.075 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 7.408553e-02 | 1.130 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 9.657617e-02 | 1.015 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 8.061686e-02 | 1.094 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 7.364038e-02 | 1.133 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 6.849908e-02 | 1.164 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 8.050560e-02 | 1.094 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 6.584727e-02 | 1.181 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 8.273293e-02 | 1.082 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 8.416502e-02 | 1.075 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 9.802627e-02 | 1.009 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 9.860771e-02 | 1.006 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 9.860771e-02 | 1.006 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 9.860771e-02 | 1.006 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 9.863191e-02 | 1.006 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 9.863191e-02 | 1.006 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 9.863191e-02 | 1.006 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 1.008944e-01 | 0.996 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 1.016284e-01 | 0.993 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.027240e-01 | 0.988 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 1.031762e-01 | 0.986 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 1.031762e-01 | 0.986 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 1.045167e-01 | 0.981 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 1.045167e-01 | 0.981 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 1.045167e-01 | 0.981 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 1.045167e-01 | 0.981 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 1.045167e-01 | 0.981 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 1.045167e-01 | 0.981 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.046881e-01 | 0.980 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 1.046881e-01 | 0.980 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.046881e-01 | 0.980 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 1.046881e-01 | 0.980 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 1.046881e-01 | 0.980 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 1.046881e-01 | 0.980 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.050242e-01 | 0.979 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.056859e-01 | 0.976 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 1.056859e-01 | 0.976 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.056859e-01 | 0.976 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 1.061934e-01 | 0.974 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 1.063800e-01 | 0.973 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 1.063800e-01 | 0.973 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.067329e-01 | 0.972 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 1.082496e-01 | 0.966 | 0 | 0 |
| S Phase | R-HSA-69242 | 1.117921e-01 | 0.952 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 1.125273e-01 | 0.949 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 1.142680e-01 | 0.942 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 1.145564e-01 | 0.941 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 1.153976e-01 | 0.938 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 1.158844e-01 | 0.936 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 1.158844e-01 | 0.936 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 1.164991e-01 | 0.934 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 1.208031e-01 | 0.918 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.212948e-01 | 0.916 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 1.216983e-01 | 0.915 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 1.216983e-01 | 0.915 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.216983e-01 | 0.915 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.216983e-01 | 0.915 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 1.216983e-01 | 0.915 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 1.216983e-01 | 0.915 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 1.216983e-01 | 0.915 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 1.231207e-01 | 0.910 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.259913e-01 | 0.900 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 1.262978e-01 | 0.899 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 1.268198e-01 | 0.897 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 1.268198e-01 | 0.897 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 1.268198e-01 | 0.897 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 1.272438e-01 | 0.895 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.272438e-01 | 0.895 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.272438e-01 | 0.895 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.272438e-01 | 0.895 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.272438e-01 | 0.895 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 1.272438e-01 | 0.895 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 1.272438e-01 | 0.895 | 0 | 0 |
| NEIL3-mediated resolution of ICLs | R-HSA-9636003 | 1.276483e-01 | 0.894 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 1.276483e-01 | 0.894 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.276483e-01 | 0.894 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.276483e-01 | 0.894 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.276483e-01 | 0.894 | 0 | 0 |
| Defective Base Excision Repair Associated with NEIL3 | R-HSA-9629232 | 1.276483e-01 | 0.894 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 1.276483e-01 | 0.894 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 1.310706e-01 | 0.882 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 1.342367e-01 | 0.872 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.361737e-01 | 0.866 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.361737e-01 | 0.866 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.367985e-01 | 0.864 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 1.383161e-01 | 0.859 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 1.383161e-01 | 0.859 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 1.386905e-01 | 0.858 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 1.386905e-01 | 0.858 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 1.393102e-01 | 0.856 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 1.393102e-01 | 0.856 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 1.393102e-01 | 0.856 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 1.393102e-01 | 0.856 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.399749e-01 | 0.854 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 1.399862e-01 | 0.854 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 1.416459e-01 | 0.849 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 1.416459e-01 | 0.849 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.416459e-01 | 0.849 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 1.416459e-01 | 0.849 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 1.489769e-01 | 0.827 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 1.489769e-01 | 0.827 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 2.390090e-01 | 0.622 | 0 | 0 |
| Activation and oligomerization of BAK protein | R-HSA-111452 | 2.390090e-01 | 0.622 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.390090e-01 | 0.622 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.390090e-01 | 0.622 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.390090e-01 | 0.622 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 2.390090e-01 | 0.622 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 2.390090e-01 | 0.622 | 0 | 0 |
| TWIK-related spinal cord K+ channel (TRESK) | R-HSA-1299344 | 2.390090e-01 | 0.622 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.390090e-01 | 0.622 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 2.390090e-01 | 0.622 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 1.498289e-01 | 0.824 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 1.498289e-01 | 0.824 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 1.498289e-01 | 0.824 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 1.498289e-01 | 0.824 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 1.498289e-01 | 0.824 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.981676e-01 | 0.703 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.981676e-01 | 0.703 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 1.981676e-01 | 0.703 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.981676e-01 | 0.703 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 1.582009e-01 | 0.801 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 1.582009e-01 | 0.801 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.582009e-01 | 0.801 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 1.582009e-01 | 0.801 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 2.480227e-01 | 0.606 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.480227e-01 | 0.606 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 2.480227e-01 | 0.606 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 2.480227e-01 | 0.606 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 2.480227e-01 | 0.606 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 1.916484e-01 | 0.717 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 1.916484e-01 | 0.717 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 1.916484e-01 | 0.717 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.916484e-01 | 0.717 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.516278e-01 | 0.819 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.776140e-01 | 0.751 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 1.776140e-01 | 0.751 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 1.776140e-01 | 0.751 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 2.266543e-01 | 0.645 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 2.266543e-01 | 0.645 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.266543e-01 | 0.645 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 2.266543e-01 | 0.645 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 2.266543e-01 | 0.645 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 1.629036e-01 | 0.788 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 2.049634e-01 | 0.688 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.049634e-01 | 0.688 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 2.049634e-01 | 0.688 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 2.627390e-01 | 0.580 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 2.627390e-01 | 0.580 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 2.627390e-01 | 0.580 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 2.627390e-01 | 0.580 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 2.627390e-01 | 0.580 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 2.627390e-01 | 0.580 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 1.853427e-01 | 0.732 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.853427e-01 | 0.732 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.679128e-01 | 0.775 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.679128e-01 | 0.775 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 1.679128e-01 | 0.775 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 2.334313e-01 | 0.632 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.334313e-01 | 0.632 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 2.334313e-01 | 0.632 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 2.088243e-01 | 0.680 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.088243e-01 | 0.680 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 1.695770e-01 | 0.771 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 2.627740e-01 | 0.580 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 2.627740e-01 | 0.580 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 2.627740e-01 | 0.580 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 2.332032e-01 | 0.632 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 1.875012e-01 | 0.727 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 2.061583e-01 | 0.686 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.061583e-01 | 0.686 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.061583e-01 | 0.686 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 2.583308e-01 | 0.588 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.583308e-01 | 0.588 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 2.927538e-01 | 0.533 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 2.927538e-01 | 0.533 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 1.828921e-01 | 0.738 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.026582e-01 | 0.693 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 2.254802e-01 | 0.647 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 2.521928e-01 | 0.598 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 2.521928e-01 | 0.598 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.840576e-01 | 0.547 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 2.840576e-01 | 0.547 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 1.985367e-01 | 0.702 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 1.985367e-01 | 0.702 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 1.985367e-01 | 0.702 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 2.749098e-01 | 0.561 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 2.090716e-01 | 0.680 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 2.980813e-01 | 0.526 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 2.760624e-01 | 0.559 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.670884e-01 | 0.777 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.536817e-01 | 0.813 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 2.394415e-01 | 0.621 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.733086e-01 | 0.563 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 2.076872e-01 | 0.683 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 2.085344e-01 | 0.681 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 2.840576e-01 | 0.547 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 1.534686e-01 | 0.814 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 1.776140e-01 | 0.751 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 1.601812e-01 | 0.795 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 2.254802e-01 | 0.647 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 2.583308e-01 | 0.588 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.831625e-01 | 0.548 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 2.453955e-01 | 0.610 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 1.516278e-01 | 0.819 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 1.940770e-01 | 0.712 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 2.090716e-01 | 0.680 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.894474e-01 | 0.723 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 1.853427e-01 | 0.732 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 1.516278e-01 | 0.819 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 2.383919e-01 | 0.623 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 1.599130e-01 | 0.796 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 1.916484e-01 | 0.717 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.627390e-01 | 0.580 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.524486e-01 | 0.817 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 2.254802e-01 | 0.647 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 2.491095e-01 | 0.604 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 1.659961e-01 | 0.780 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.629036e-01 | 0.788 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 2.491095e-01 | 0.604 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 1.981676e-01 | 0.703 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 1.582009e-01 | 0.801 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 2.480227e-01 | 0.606 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.629036e-01 | 0.788 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 1.877955e-01 | 0.726 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.536276e-01 | 0.814 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.828921e-01 | 0.738 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 2.954787e-01 | 0.529 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.521665e-01 | 0.818 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 2.334313e-01 | 0.632 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.940770e-01 | 0.712 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 2.147194e-01 | 0.668 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 1.795753e-01 | 0.746 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 1.795753e-01 | 0.746 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.981676e-01 | 0.703 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 1.916484e-01 | 0.717 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 2.049634e-01 | 0.688 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 1.521665e-01 | 0.818 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 2.061583e-01 | 0.686 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 2.026582e-01 | 0.693 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 1.870206e-01 | 0.728 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 1.668816e-01 | 0.778 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 2.749098e-01 | 0.561 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 1.760147e-01 | 0.754 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 1.760147e-01 | 0.754 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.012209e-01 | 0.696 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.679128e-01 | 0.775 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.840576e-01 | 0.547 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 2.867077e-01 | 0.543 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 2.954787e-01 | 0.529 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 2.408612e-01 | 0.618 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 1.601812e-01 | 0.795 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 1.776140e-01 | 0.751 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 1.856554e-01 | 0.731 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 2.501425e-01 | 0.602 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 1.981676e-01 | 0.703 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 2.266543e-01 | 0.645 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 2.049634e-01 | 0.688 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 2.334313e-01 | 0.632 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 2.088243e-01 | 0.680 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 1.692965e-01 | 0.771 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 1.681420e-01 | 0.774 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.536817e-01 | 0.813 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 1.866762e-01 | 0.729 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 1.866762e-01 | 0.729 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 1.866762e-01 | 0.729 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 2.290349e-01 | 0.640 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 2.098850e-01 | 0.678 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 2.239515e-01 | 0.650 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 2.334313e-01 | 0.632 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 1.641604e-01 | 0.785 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.695770e-01 | 0.771 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 2.954787e-01 | 0.529 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 2.927538e-01 | 0.533 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.061583e-01 | 0.686 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 2.236640e-01 | 0.650 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 2.540035e-01 | 0.595 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 1.692965e-01 | 0.771 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 2.867077e-01 | 0.543 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 1.981676e-01 | 0.703 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 1.516278e-01 | 0.819 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.516278e-01 | 0.819 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.516278e-01 | 0.819 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 2.266543e-01 | 0.645 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 2.049634e-01 | 0.688 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 2.627390e-01 | 0.580 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.828921e-01 | 0.738 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 2.034241e-01 | 0.692 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.868371e-01 | 0.729 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 2.354810e-01 | 0.628 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 1.679128e-01 | 0.775 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 2.680275e-01 | 0.572 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.989939e-01 | 0.701 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.682812e-01 | 0.774 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 1.875012e-01 | 0.727 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.641604e-01 | 0.785 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 2.980813e-01 | 0.526 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 1.875012e-01 | 0.727 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 1.582009e-01 | 0.801 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 2.266543e-01 | 0.645 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 2.167691e-01 | 0.664 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.521928e-01 | 0.598 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 2.627390e-01 | 0.580 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 2.959729e-01 | 0.529 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 2.115489e-01 | 0.675 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 2.867077e-01 | 0.543 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.266543e-01 | 0.645 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 1.708230e-01 | 0.767 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 2.627740e-01 | 0.580 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 1.891187e-01 | 0.723 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 2.583308e-01 | 0.588 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 1.629036e-01 | 0.788 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 2.982200e-01 | 0.525 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 2.982200e-01 | 0.525 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 2.982200e-01 | 0.525 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 2.982200e-01 | 0.525 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 2.982200e-01 | 0.525 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 2.982200e-01 | 0.525 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 2.982200e-01 | 0.525 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 2.982200e-01 | 0.525 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 2.982200e-01 | 0.525 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.994607e-01 | 0.524 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 2.994607e-01 | 0.524 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 2.994607e-01 | 0.524 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 2.994607e-01 | 0.524 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 2.994607e-01 | 0.524 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 2.994607e-01 | 0.524 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 3.074655e-01 | 0.512 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.074655e-01 | 0.512 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 3.074655e-01 | 0.512 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 3.074655e-01 | 0.512 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 3.079520e-01 | 0.512 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.079520e-01 | 0.512 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 3.079520e-01 | 0.512 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 3.102362e-01 | 0.508 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 3.128905e-01 | 0.505 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 3.152029e-01 | 0.501 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 3.152029e-01 | 0.501 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 3.216046e-01 | 0.493 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.231434e-01 | 0.491 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 3.231434e-01 | 0.491 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 3.231434e-01 | 0.491 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 3.231434e-01 | 0.491 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 3.231434e-01 | 0.491 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 3.231434e-01 | 0.491 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 3.231434e-01 | 0.491 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 3.232949e-01 | 0.490 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 3.249165e-01 | 0.488 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 3.294860e-01 | 0.482 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 3.356998e-01 | 0.474 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 3.361595e-01 | 0.473 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 3.361595e-01 | 0.473 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 3.361595e-01 | 0.473 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 3.361595e-01 | 0.473 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5660724 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5619081 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) | R-HSA-5619048 | 3.361595e-01 | 0.473 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.361595e-01 | 0.473 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 3.361595e-01 | 0.473 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 3.361595e-01 | 0.473 | 0 | 0 |
| MyD88 deficiency (TLR5) | R-HSA-5602680 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC12A3 causes Gitelman syndrome (GS) | R-HSA-5619087 | 3.361595e-01 | 0.473 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) | R-HSA-5619045 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SLC34A2 causes PALM | R-HSA-5687583 | 3.361595e-01 | 0.473 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.361595e-01 | 0.473 | 0 | 0 |
| Defective SERPING1 causes hereditary angioedema | R-HSA-9657689 | 3.361595e-01 | 0.473 | 0 | 0 |
| NTRK3 as a dependence receptor | R-HSA-9603505 | 3.361595e-01 | 0.473 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 3.364211e-01 | 0.473 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 3.364211e-01 | 0.473 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 3.364211e-01 | 0.473 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 3.366734e-01 | 0.473 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 3.367229e-01 | 0.473 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 3.367229e-01 | 0.473 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 3.367229e-01 | 0.473 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 3.367229e-01 | 0.473 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 3.393892e-01 | 0.469 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 3.468043e-01 | 0.460 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 3.478602e-01 | 0.459 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 3.478602e-01 | 0.459 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 3.478602e-01 | 0.459 | 0 | 0 |
| H139Hfs13* PPM1K causes a mild variant of MSUD | R-HSA-9912529 | 3.478602e-01 | 0.459 | 0 | 0 |
| Leukotriene receptors | R-HSA-391906 | 3.478602e-01 | 0.459 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 3.478602e-01 | 0.459 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 3.481912e-01 | 0.458 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 3.499800e-01 | 0.456 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 3.512339e-01 | 0.454 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 3.537287e-01 | 0.451 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 3.537287e-01 | 0.451 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 3.537287e-01 | 0.451 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 3.553349e-01 | 0.449 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.603621e-01 | 0.443 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 3.603621e-01 | 0.443 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 3.618607e-01 | 0.441 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 3.618607e-01 | 0.441 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 3.622198e-01 | 0.441 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 3.633797e-01 | 0.440 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 3.636063e-01 | 0.439 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 3.636063e-01 | 0.439 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 3.693050e-01 | 0.433 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 3.693050e-01 | 0.433 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 3.693050e-01 | 0.433 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 3.731212e-01 | 0.428 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 3.732685e-01 | 0.428 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 3.732685e-01 | 0.428 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 3.732685e-01 | 0.428 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.732685e-01 | 0.428 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 3.732685e-01 | 0.428 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 3.782761e-01 | 0.422 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 3.785983e-01 | 0.422 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 3.791203e-01 | 0.421 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 3.843114e-01 | 0.415 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 3.843114e-01 | 0.415 | 0 | 0 |
| PKA activation | R-HSA-163615 | 3.843114e-01 | 0.415 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 3.843114e-01 | 0.415 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 3.843114e-01 | 0.415 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 3.900755e-01 | 0.409 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 3.900755e-01 | 0.409 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 3.900755e-01 | 0.409 | 0 | 0 |
| Disease | R-HSA-1643685 | 3.929978e-01 | 0.406 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 3.932893e-01 | 0.405 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 3.950755e-01 | 0.403 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 3.950755e-01 | 0.403 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 3.959301e-01 | 0.402 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 3.959850e-01 | 0.402 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 3.962679e-01 | 0.402 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis | R-HSA-9632974 | 3.962679e-01 | 0.402 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 3.962679e-01 | 0.402 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 3.962679e-01 | 0.402 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.962679e-01 | 0.402 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 3.962679e-01 | 0.402 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 3.962679e-01 | 0.402 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 4.075891e-01 | 0.390 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 4.096975e-01 | 0.388 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 4.096975e-01 | 0.388 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 4.096975e-01 | 0.388 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 4.096975e-01 | 0.388 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.096975e-01 | 0.388 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 4.096975e-01 | 0.388 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 4.147103e-01 | 0.382 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 4.147103e-01 | 0.382 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 4.163616e-01 | 0.381 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 4.170272e-01 | 0.380 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 4.172414e-01 | 0.380 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 4.172414e-01 | 0.380 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 4.172414e-01 | 0.380 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 4.209124e-01 | 0.376 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 4.209124e-01 | 0.376 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 4.209124e-01 | 0.376 | 0 | 0 |
| Essential pentosuria | R-HSA-5662853 | 4.209124e-01 | 0.376 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 4.209124e-01 | 0.376 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 4.209124e-01 | 0.376 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 4.209124e-01 | 0.376 | 0 | 0 |
| Defective factor XII causes hereditary angioedema | R-HSA-9657688 | 4.209124e-01 | 0.376 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 4.209124e-01 | 0.376 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 4.209124e-01 | 0.376 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 4.239833e-01 | 0.373 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 4.280606e-01 | 0.368 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.344926e-01 | 0.362 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 4.366999e-01 | 0.360 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 4.389096e-01 | 0.358 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 4.389096e-01 | 0.358 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 4.429488e-01 | 0.354 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 4.429488e-01 | 0.354 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 4.429488e-01 | 0.354 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 4.429488e-01 | 0.354 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 4.429488e-01 | 0.354 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 4.429488e-01 | 0.354 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 4.429488e-01 | 0.354 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 4.431019e-01 | 0.353 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 4.431019e-01 | 0.353 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.447625e-01 | 0.352 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 4.453773e-01 | 0.351 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 4.454484e-01 | 0.351 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 4.454484e-01 | 0.351 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 4.454484e-01 | 0.351 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 4.487951e-01 | 0.348 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 4.487951e-01 | 0.348 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 4.502933e-01 | 0.347 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 4.502933e-01 | 0.347 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 4.502933e-01 | 0.347 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 4.502933e-01 | 0.347 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 4.502933e-01 | 0.347 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 4.535095e-01 | 0.343 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 4.569483e-01 | 0.340 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 4.569483e-01 | 0.340 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 4.606596e-01 | 0.337 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 4.606596e-01 | 0.337 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 4.606596e-01 | 0.337 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 4.647138e-01 | 0.333 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 4.647138e-01 | 0.333 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 4.647665e-01 | 0.333 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 4.682014e-01 | 0.330 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 4.690818e-01 | 0.329 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 4.692145e-01 | 0.329 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 4.724246e-01 | 0.326 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 4.725193e-01 | 0.326 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 4.743234e-01 | 0.324 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 4.743234e-01 | 0.324 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 4.743234e-01 | 0.324 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 4.743234e-01 | 0.324 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 4.743234e-01 | 0.324 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 4.803046e-01 | 0.318 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 4.803046e-01 | 0.318 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 4.803046e-01 | 0.318 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 4.803046e-01 | 0.318 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.803046e-01 | 0.318 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 4.803046e-01 | 0.318 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 4.803046e-01 | 0.318 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.803046e-01 | 0.318 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 4.822180e-01 | 0.317 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 4.860010e-01 | 0.313 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 4.875551e-01 | 0.312 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 4.875551e-01 | 0.312 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 4.875551e-01 | 0.312 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 4.875551e-01 | 0.312 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 4.875551e-01 | 0.312 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 4.875551e-01 | 0.312 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 4.875551e-01 | 0.312 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 4.875551e-01 | 0.312 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 4.875551e-01 | 0.312 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 4.875551e-01 | 0.312 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 4.875551e-01 | 0.312 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 4.875551e-01 | 0.312 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 4.875551e-01 | 0.312 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 4.880810e-01 | 0.312 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 4.880810e-01 | 0.312 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 4.880810e-01 | 0.312 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 4.911987e-01 | 0.309 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 4.912542e-01 | 0.309 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 4.948491e-01 | 0.306 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 4.948491e-01 | 0.306 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 4.948491e-01 | 0.306 | 0 | 0 |
| Defective HPRT1 disrupts guanine and hypoxanthine salvage | R-HSA-9734281 | 4.948491e-01 | 0.306 | 0 | 0 |
| Signalling to STAT3 | R-HSA-198745 | 4.948491e-01 | 0.306 | 0 | 0 |
| Defective ABCA1 causes TGD | R-HSA-5682113 | 4.948491e-01 | 0.306 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 4.948491e-01 | 0.306 | 0 | 0 |
| Activation of BMF and translocation to mitochondria | R-HSA-139910 | 4.948491e-01 | 0.306 | 0 | 0 |
| Type II Na+/Pi cotransporters | R-HSA-427589 | 4.948491e-01 | 0.306 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 4.948491e-01 | 0.306 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 4.948491e-01 | 0.306 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 4.949307e-01 | 0.305 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 4.949307e-01 | 0.305 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 4.949307e-01 | 0.305 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 4.953116e-01 | 0.305 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 4.967532e-01 | 0.304 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 4.969825e-01 | 0.304 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 4.988934e-01 | 0.302 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 4.990097e-01 | 0.302 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 5.032668e-01 | 0.298 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 5.032668e-01 | 0.298 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 5.037856e-01 | 0.298 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 5.043250e-01 | 0.297 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 5.078481e-01 | 0.294 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 5.097945e-01 | 0.293 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 5.111104e-01 | 0.291 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 5.136635e-01 | 0.289 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 5.136635e-01 | 0.289 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 5.140899e-01 | 0.289 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 5.140899e-01 | 0.289 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 5.140899e-01 | 0.289 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 5.140899e-01 | 0.289 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 5.140899e-01 | 0.289 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 5.140899e-01 | 0.289 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 5.140899e-01 | 0.289 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 5.140899e-01 | 0.289 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 5.140899e-01 | 0.289 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 5.140899e-01 | 0.289 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 5.148230e-01 | 0.288 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 5.148230e-01 | 0.288 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 5.192330e-01 | 0.285 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 5.201663e-01 | 0.284 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 5.201663e-01 | 0.284 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 5.211464e-01 | 0.283 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 5.212883e-01 | 0.283 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 5.298556e-01 | 0.276 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 5.298556e-01 | 0.276 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 5.298556e-01 | 0.276 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 5.298556e-01 | 0.276 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 5.298556e-01 | 0.276 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 5.298556e-01 | 0.276 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 5.298556e-01 | 0.276 | 0 | 0 |
| LTC4-CYSLTR mediated IL4 production | R-HSA-9664535 | 5.298556e-01 | 0.276 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 5.298556e-01 | 0.276 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 5.298556e-01 | 0.276 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 5.298556e-01 | 0.276 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 5.298556e-01 | 0.276 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 5.314845e-01 | 0.275 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 5.314845e-01 | 0.275 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 5.337407e-01 | 0.273 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 5.337407e-01 | 0.273 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 5.337407e-01 | 0.273 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 5.384325e-01 | 0.269 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 5.448469e-01 | 0.264 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 5.448469e-01 | 0.264 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 5.452120e-01 | 0.263 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 5.463136e-01 | 0.263 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 5.466647e-01 | 0.262 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 5.466647e-01 | 0.262 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 5.466647e-01 | 0.262 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 5.466647e-01 | 0.262 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 5.466647e-01 | 0.262 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 5.552283e-01 | 0.256 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 5.583482e-01 | 0.253 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 5.588854e-01 | 0.253 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 5.593494e-01 | 0.252 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 5.593494e-01 | 0.252 | 0 | 0 |
| Defective MAT1A causes MATD | R-HSA-5579024 | 5.593494e-01 | 0.252 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 5.593494e-01 | 0.252 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 5.593494e-01 | 0.252 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 5.593494e-01 | 0.252 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 5.593494e-01 | 0.252 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 5.593494e-01 | 0.252 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.593494e-01 | 0.252 | 0 | 0 |
| Interleukin-38 signaling | R-HSA-9007892 | 5.593494e-01 | 0.252 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.638576e-01 | 0.249 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 5.654939e-01 | 0.248 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 5.689080e-01 | 0.245 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 5.697120e-01 | 0.244 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 5.697120e-01 | 0.244 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 5.697120e-01 | 0.244 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 5.697120e-01 | 0.244 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 5.714207e-01 | 0.243 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 5.779228e-01 | 0.238 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 5.779228e-01 | 0.238 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 5.779228e-01 | 0.238 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 5.779228e-01 | 0.238 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 5.779228e-01 | 0.238 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 5.779228e-01 | 0.238 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 5.817308e-01 | 0.235 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 5.853511e-01 | 0.233 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 5.853511e-01 | 0.233 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 5.853948e-01 | 0.233 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 5.853948e-01 | 0.233 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 5.853948e-01 | 0.233 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 5.922946e-01 | 0.227 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 5.987213e-01 | 0.223 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 5.987213e-01 | 0.223 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 5.989584e-01 | 0.223 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 6.047499e-01 | 0.218 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 6.070588e-01 | 0.217 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 6.070588e-01 | 0.217 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 6.070588e-01 | 0.217 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 6.070588e-01 | 0.217 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 6.070588e-01 | 0.217 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 6.070588e-01 | 0.217 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 6.070588e-01 | 0.217 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 6.077875e-01 | 0.216 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 6.077875e-01 | 0.216 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 6.077875e-01 | 0.216 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 6.077875e-01 | 0.216 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 6.088532e-01 | 0.215 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 6.104387e-01 | 0.214 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 6.109531e-01 | 0.214 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 6.109531e-01 | 0.214 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 6.109531e-01 | 0.214 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 6.149609e-01 | 0.211 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 6.156173e-01 | 0.211 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 6.156173e-01 | 0.211 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 6.156173e-01 | 0.211 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 6.156173e-01 | 0.211 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 6.156173e-01 | 0.211 | 0 | 0 |
| Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) | R-HSA-5619067 | 6.156173e-01 | 0.211 | 0 | 0 |
| Trafficking of myristoylated proteins to the cilium | R-HSA-5624138 | 6.156173e-01 | 0.211 | 0 | 0 |
| PTK6 Activates STAT3 | R-HSA-8849474 | 6.156173e-01 | 0.211 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 6.156173e-01 | 0.211 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 6.156173e-01 | 0.211 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 6.156173e-01 | 0.211 | 0 | 0 |
| Inositol transporters | R-HSA-429593 | 6.156173e-01 | 0.211 | 0 | 0 |
| Biosynthesis of DPAn-3-derived 13-series resolvins | R-HSA-9026403 | 6.156173e-01 | 0.211 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 6.156173e-01 | 0.211 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 6.156173e-01 | 0.211 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 6.156173e-01 | 0.211 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 6.156173e-01 | 0.211 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 6.156173e-01 | 0.211 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 6.156173e-01 | 0.211 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 6.192705e-01 | 0.208 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 6.192705e-01 | 0.208 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 6.192705e-01 | 0.208 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 6.236610e-01 | 0.205 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 6.269848e-01 | 0.203 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 6.302325e-01 | 0.200 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 6.355149e-01 | 0.197 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 6.355149e-01 | 0.197 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 6.355149e-01 | 0.197 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 6.355149e-01 | 0.197 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 6.355149e-01 | 0.197 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 6.362080e-01 | 0.196 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 6.362080e-01 | 0.196 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 6.362080e-01 | 0.196 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 6.362080e-01 | 0.196 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 6.362080e-01 | 0.196 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 6.368695e-01 | 0.196 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 6.370067e-01 | 0.196 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 6.392085e-01 | 0.194 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 6.392085e-01 | 0.194 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 6.406725e-01 | 0.193 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 6.418871e-01 | 0.193 | 0 | 0 |
| Maple Syrup Urine Disease | R-HSA-9865114 | 6.418871e-01 | 0.193 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 6.418871e-01 | 0.193 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 6.418871e-01 | 0.193 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 6.418871e-01 | 0.193 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 6.418871e-01 | 0.193 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 6.418871e-01 | 0.193 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 6.418871e-01 | 0.193 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 6.418871e-01 | 0.193 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 6.420593e-01 | 0.192 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 6.420593e-01 | 0.192 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.446894e-01 | 0.191 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 6.561465e-01 | 0.183 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 6.579914e-01 | 0.182 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 6.579914e-01 | 0.182 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 6.585107e-01 | 0.181 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 6.585107e-01 | 0.181 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 6.590474e-01 | 0.181 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 6.590474e-01 | 0.181 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 6.590474e-01 | 0.181 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 6.590474e-01 | 0.181 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 6.599238e-01 | 0.181 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 6.618743e-01 | 0.179 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 6.631559e-01 | 0.178 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 6.631559e-01 | 0.178 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 6.647030e-01 | 0.177 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.647030e-01 | 0.177 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.647030e-01 | 0.177 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.647030e-01 | 0.177 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 6.647030e-01 | 0.177 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.647030e-01 | 0.177 | 0 | 0 |
| Loss-of-function mutations in DBT cause MSUD2 | R-HSA-9865113 | 6.647030e-01 | 0.177 | 0 | 0 |
| Loss-of-function mutations in DLD cause MSUD3/DLDD | R-HSA-9907570 | 6.647030e-01 | 0.177 | 0 | 0 |
| Terminal pathway of complement | R-HSA-166665 | 6.647030e-01 | 0.177 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 6.647030e-01 | 0.177 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 6.647030e-01 | 0.177 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 6.647030e-01 | 0.177 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 6.647030e-01 | 0.177 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.647030e-01 | 0.177 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 6.647030e-01 | 0.177 | 0 | 0 |
| Acetylcholine inhibits contraction of outer hair cells | R-HSA-9667769 | 6.647030e-01 | 0.177 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 6.647030e-01 | 0.177 | 0 | 0 |
| Diseases of Base Excision Repair | R-HSA-9605308 | 6.647030e-01 | 0.177 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 6.669099e-01 | 0.176 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 6.683557e-01 | 0.175 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 6.692846e-01 | 0.174 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 6.742309e-01 | 0.171 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 6.742309e-01 | 0.171 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 6.742309e-01 | 0.171 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 6.742309e-01 | 0.171 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 6.742309e-01 | 0.171 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 6.747541e-01 | 0.171 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 6.771574e-01 | 0.169 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 6.771574e-01 | 0.169 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 6.772372e-01 | 0.169 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 6.783051e-01 | 0.169 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 6.815298e-01 | 0.167 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 6.815298e-01 | 0.167 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 6.874035e-01 | 0.163 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 6.874035e-01 | 0.163 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 6.886223e-01 | 0.162 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 6.886223e-01 | 0.162 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 6.886223e-01 | 0.162 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 6.886223e-01 | 0.162 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.938162e-01 | 0.159 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 6.951341e-01 | 0.158 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 6.977959e-01 | 0.156 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 6.977959e-01 | 0.156 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 7.029512e-01 | 0.153 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 7.029512e-01 | 0.153 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 7.041568e-01 | 0.152 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 7.041568e-01 | 0.152 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 7.041568e-01 | 0.152 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 7.041568e-01 | 0.152 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 7.041568e-01 | 0.152 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 7.075230e-01 | 0.150 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 7.075230e-01 | 0.150 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 7.075230e-01 | 0.150 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 7.075230e-01 | 0.150 | 0 | 0 |
| Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD | R-HSA-9865125 | 7.075230e-01 | 0.150 | 0 | 0 |
| Branched-chain ketoacid dehydrogenase kinase deficiency | R-HSA-9912481 | 7.075230e-01 | 0.150 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 7.075230e-01 | 0.150 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 7.075230e-01 | 0.150 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 7.075230e-01 | 0.150 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 7.075230e-01 | 0.150 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 7.075230e-01 | 0.150 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 7.075230e-01 | 0.150 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 7.075230e-01 | 0.150 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 7.075230e-01 | 0.150 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 7.075230e-01 | 0.150 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 7.075230e-01 | 0.150 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 7.075230e-01 | 0.150 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 7.096416e-01 | 0.149 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 7.101599e-01 | 0.149 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 7.124306e-01 | 0.147 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 7.147155e-01 | 0.146 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 7.147155e-01 | 0.146 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 7.164557e-01 | 0.145 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.164557e-01 | 0.145 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 7.216194e-01 | 0.142 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 7.233101e-01 | 0.141 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 7.257523e-01 | 0.139 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 7.257523e-01 | 0.139 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 7.290413e-01 | 0.137 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 7.290413e-01 | 0.137 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 7.290413e-01 | 0.137 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 7.317548e-01 | 0.136 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 7.317548e-01 | 0.136 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 7.317548e-01 | 0.136 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.317548e-01 | 0.136 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 7.317548e-01 | 0.136 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 7.342820e-01 | 0.134 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 7.347186e-01 | 0.134 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 7.347529e-01 | 0.134 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 7.351529e-01 | 0.134 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 7.426130e-01 | 0.129 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 7.426130e-01 | 0.129 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 7.426130e-01 | 0.129 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 7.448767e-01 | 0.128 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 7.448767e-01 | 0.128 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 7.448767e-01 | 0.128 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.448767e-01 | 0.128 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 7.448767e-01 | 0.128 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 7.448767e-01 | 0.128 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 7.448767e-01 | 0.128 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 7.448767e-01 | 0.128 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.448767e-01 | 0.128 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 7.448767e-01 | 0.128 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.448767e-01 | 0.128 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 7.448767e-01 | 0.128 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 7.448767e-01 | 0.128 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 7.448767e-01 | 0.128 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 7.448767e-01 | 0.128 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 7.448767e-01 | 0.128 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 7.448767e-01 | 0.128 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 7.448767e-01 | 0.128 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 7.493004e-01 | 0.125 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 7.512775e-01 | 0.124 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 7.512775e-01 | 0.124 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 7.516909e-01 | 0.124 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 7.551796e-01 | 0.122 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 7.562698e-01 | 0.121 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 7.562698e-01 | 0.121 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 7.562698e-01 | 0.121 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 7.562698e-01 | 0.121 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 7.569679e-01 | 0.121 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 7.571313e-01 | 0.121 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 7.571313e-01 | 0.121 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 7.571313e-01 | 0.121 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 7.571313e-01 | 0.121 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 7.571313e-01 | 0.121 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 7.571313e-01 | 0.121 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 7.571313e-01 | 0.121 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 7.571313e-01 | 0.121 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 7.574636e-01 | 0.121 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 7.574739e-01 | 0.121 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 7.598211e-01 | 0.119 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 7.674495e-01 | 0.115 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 7.760060e-01 | 0.110 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 7.760060e-01 | 0.110 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 7.760060e-01 | 0.110 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 7.761857e-01 | 0.110 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 7.769169e-01 | 0.110 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 7.774616e-01 | 0.109 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 7.774616e-01 | 0.109 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 7.774616e-01 | 0.109 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 7.774616e-01 | 0.109 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.774616e-01 | 0.109 | 0 | 0 |
| Highly calcium permeable nicotinic acetylcholine receptors | R-HSA-629597 | 7.774616e-01 | 0.109 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 7.774616e-01 | 0.109 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 7.774616e-01 | 0.109 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 7.774616e-01 | 0.109 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 7.774616e-01 | 0.109 | 0 | 0 |
| Nucleotide salvage defects | R-HSA-9734207 | 7.774616e-01 | 0.109 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 7.774616e-01 | 0.109 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 7.774616e-01 | 0.109 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 7.774616e-01 | 0.109 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 7.775655e-01 | 0.109 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 7.776612e-01 | 0.109 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.781106e-01 | 0.109 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 7.804035e-01 | 0.108 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 7.804035e-01 | 0.108 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 7.804035e-01 | 0.108 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 7.804035e-01 | 0.108 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 7.828094e-01 | 0.106 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 7.828094e-01 | 0.106 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 7.857905e-01 | 0.105 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 7.936697e-01 | 0.100 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 7.936697e-01 | 0.100 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 7.943489e-01 | 0.100 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 7.944090e-01 | 0.100 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 7.944090e-01 | 0.100 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 7.973719e-01 | 0.098 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 7.973719e-01 | 0.098 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 7.973719e-01 | 0.098 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 7.973719e-01 | 0.098 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 8.016948e-01 | 0.096 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 8.016948e-01 | 0.096 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 8.016948e-01 | 0.096 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 8.058864e-01 | 0.094 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 8.058864e-01 | 0.094 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 8.058864e-01 | 0.094 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 8.058864e-01 | 0.094 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 8.058864e-01 | 0.094 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 8.058864e-01 | 0.094 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 8.058864e-01 | 0.094 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 8.096165e-01 | 0.092 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 8.096165e-01 | 0.092 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 8.096165e-01 | 0.092 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 8.111548e-01 | 0.091 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 8.115319e-01 | 0.091 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 8.115319e-01 | 0.091 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 8.144277e-01 | 0.089 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 8.162468e-01 | 0.088 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.186151e-01 | 0.087 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.211316e-01 | 0.086 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 8.211316e-01 | 0.086 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 8.241785e-01 | 0.084 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 8.241785e-01 | 0.084 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 8.241785e-01 | 0.084 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 8.264137e-01 | 0.083 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 8.274316e-01 | 0.082 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.274316e-01 | 0.082 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 8.274316e-01 | 0.082 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 8.281880e-01 | 0.082 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.294687e-01 | 0.081 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.296229e-01 | 0.081 | 0 | 0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | R-HSA-629594 | 8.306819e-01 | 0.081 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 8.306819e-01 | 0.081 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 8.306819e-01 | 0.081 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 8.306819e-01 | 0.081 | 0 | 0 |
| Serotonin receptors | R-HSA-390666 | 8.306819e-01 | 0.081 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 8.306819e-01 | 0.081 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 8.334957e-01 | 0.079 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 8.364654e-01 | 0.078 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 8.364654e-01 | 0.078 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 8.388400e-01 | 0.076 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 8.388400e-01 | 0.076 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 8.388400e-01 | 0.076 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 8.388400e-01 | 0.076 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 8.388400e-01 | 0.076 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 8.388400e-01 | 0.076 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.404572e-01 | 0.075 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 8.480396e-01 | 0.072 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 8.499247e-01 | 0.071 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 8.500496e-01 | 0.071 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 8.523114e-01 | 0.069 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 8.523114e-01 | 0.069 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 8.523114e-01 | 0.069 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 8.523114e-01 | 0.069 | 0 | 0 |
| Biosynthesis of DPAn-3-derived maresins | R-HSA-9026290 | 8.523114e-01 | 0.069 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 8.523114e-01 | 0.069 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 8.523114e-01 | 0.069 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 8.549445e-01 | 0.068 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 8.549445e-01 | 0.068 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 8.549445e-01 | 0.068 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.549445e-01 | 0.068 | 0 | 0 |
| Melanin biosynthesis | R-HSA-5662702 | 8.549445e-01 | 0.068 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.557998e-01 | 0.068 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 8.557998e-01 | 0.068 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 8.557998e-01 | 0.068 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 8.589266e-01 | 0.066 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 8.625590e-01 | 0.064 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 8.680725e-01 | 0.061 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 8.680725e-01 | 0.061 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.683904e-01 | 0.061 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 8.695657e-01 | 0.061 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 8.695657e-01 | 0.061 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 8.711789e-01 | 0.060 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 8.711789e-01 | 0.060 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 8.711789e-01 | 0.060 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 8.711789e-01 | 0.060 | 0 | 0 |
| Presynaptic nicotinic acetylcholine receptors | R-HSA-622323 | 8.711789e-01 | 0.060 | 0 | 0 |
| Scavenging by Class H Receptors | R-HSA-3000497 | 8.711789e-01 | 0.060 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 8.711789e-01 | 0.060 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 8.711789e-01 | 0.060 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 8.717538e-01 | 0.060 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 8.717538e-01 | 0.060 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 8.727844e-01 | 0.059 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 8.770905e-01 | 0.057 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 8.777555e-01 | 0.057 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 8.787451e-01 | 0.056 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 8.787451e-01 | 0.056 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 8.799439e-01 | 0.056 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 8.800001e-01 | 0.056 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 8.827582e-01 | 0.054 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 8.828198e-01 | 0.054 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 8.828198e-01 | 0.054 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 8.838172e-01 | 0.054 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 8.855849e-01 | 0.053 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 8.876370e-01 | 0.052 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.876370e-01 | 0.052 | 0 | 0 |
| Biosynthesis of DPAn-3-derived protectins and resolvins | R-HSA-9026286 | 8.876370e-01 | 0.052 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 8.876370e-01 | 0.052 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.876370e-01 | 0.052 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 8.876370e-01 | 0.052 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 8.876370e-01 | 0.052 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.876370e-01 | 0.052 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 8.908809e-01 | 0.050 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 8.935768e-01 | 0.049 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 8.935768e-01 | 0.049 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.935768e-01 | 0.049 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 9.005167e-01 | 0.046 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 9.005167e-01 | 0.046 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 9.019933e-01 | 0.045 | 0 | 0 |
| Acetylcholine binding and downstream events | R-HSA-181431 | 9.019933e-01 | 0.045 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 9.019933e-01 | 0.045 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 9.019933e-01 | 0.045 | 0 | 0 |
| Postsynaptic nicotinic acetylcholine receptors | R-HSA-622327 | 9.019933e-01 | 0.045 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 9.019933e-01 | 0.045 | 0 | 0 |
| rRNA modification in the mitochondrion | R-HSA-6793080 | 9.019933e-01 | 0.045 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.056628e-01 | 0.043 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.056628e-01 | 0.043 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.056628e-01 | 0.043 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 9.056628e-01 | 0.043 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.093402e-01 | 0.041 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 9.095397e-01 | 0.041 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.095397e-01 | 0.041 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.095397e-01 | 0.041 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.113289e-01 | 0.040 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.118153e-01 | 0.040 | 0 | 0 |
| BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV | R-HSA-9859138 | 9.145160e-01 | 0.039 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 9.145160e-01 | 0.039 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 9.145160e-01 | 0.039 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 9.145160e-01 | 0.039 | 0 | 0 |
| Biosynthesis of E-series 18(R)-resolvins | R-HSA-9023661 | 9.145160e-01 | 0.039 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 9.145160e-01 | 0.039 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 9.145160e-01 | 0.039 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 9.145160e-01 | 0.039 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 9.145160e-01 | 0.039 | 0 | 0 |
| Glycerophospholipid catabolism | R-HSA-6814848 | 9.145160e-01 | 0.039 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.147492e-01 | 0.039 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.154549e-01 | 0.038 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.154549e-01 | 0.038 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 9.178134e-01 | 0.037 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.178134e-01 | 0.037 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.178134e-01 | 0.037 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.178134e-01 | 0.037 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 9.178134e-01 | 0.037 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.242856e-01 | 0.034 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.242856e-01 | 0.034 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.242856e-01 | 0.034 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.242856e-01 | 0.034 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.242856e-01 | 0.034 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 9.253907e-01 | 0.034 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 9.254393e-01 | 0.034 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 9.254393e-01 | 0.034 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 9.254393e-01 | 0.034 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 9.254393e-01 | 0.034 | 0 | 0 |
| Protein repair | R-HSA-5676934 | 9.254393e-01 | 0.034 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 9.254393e-01 | 0.034 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 9.254393e-01 | 0.034 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 9.254393e-01 | 0.034 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 9.270045e-01 | 0.033 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.322407e-01 | 0.030 | 0 | 0 |
| Diseases of branched-chain amino acid catabolism | R-HSA-9865118 | 9.322407e-01 | 0.030 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.322407e-01 | 0.030 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.322407e-01 | 0.030 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.322407e-01 | 0.030 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.349673e-01 | 0.029 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 9.349673e-01 | 0.029 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 9.349673e-01 | 0.029 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.360793e-01 | 0.029 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.371773e-01 | 0.028 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.386554e-01 | 0.027 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.393997e-01 | 0.027 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.424160e-01 | 0.026 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 9.432783e-01 | 0.025 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 9.432783e-01 | 0.025 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 9.432783e-01 | 0.025 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 9.432783e-01 | 0.025 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 9.432783e-01 | 0.025 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 9.432783e-01 | 0.025 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 9.432783e-01 | 0.025 | 0 | 0 |
| Formation of xylulose-5-phosphate | R-HSA-5661270 | 9.432783e-01 | 0.025 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 9.432783e-01 | 0.025 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 9.432783e-01 | 0.025 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.432783e-01 | 0.025 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.444364e-01 | 0.025 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.458362e-01 | 0.024 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.476661e-01 | 0.023 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.476661e-01 | 0.023 | 0 | 0 |
| Biosynthesis of aspirin-triggered D-series resolvins | R-HSA-9020265 | 9.505275e-01 | 0.022 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 9.505275e-01 | 0.022 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 9.505275e-01 | 0.022 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 9.505275e-01 | 0.022 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.516177e-01 | 0.022 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.516177e-01 | 0.022 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.516177e-01 | 0.022 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.542717e-01 | 0.020 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.542717e-01 | 0.020 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.554688e-01 | 0.020 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.555498e-01 | 0.020 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.555498e-01 | 0.020 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.565879e-01 | 0.019 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.568066e-01 | 0.019 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.568066e-01 | 0.019 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 9.568507e-01 | 0.019 | 0 | 0 |
| Biosynthesis of Lipoxins (LX) | R-HSA-2142700 | 9.568507e-01 | 0.019 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.568507e-01 | 0.019 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 9.568507e-01 | 0.019 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 9.568507e-01 | 0.019 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.593846e-01 | 0.018 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.594771e-01 | 0.018 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.614599e-01 | 0.017 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 9.623660e-01 | 0.017 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.623660e-01 | 0.017 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 9.623660e-01 | 0.017 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.623660e-01 | 0.017 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 9.623660e-01 | 0.017 | 0 | 0 |
| HDL remodeling | R-HSA-8964058 | 9.623660e-01 | 0.017 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 9.623660e-01 | 0.017 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.628531e-01 | 0.016 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.656297e-01 | 0.015 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.664631e-01 | 0.015 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.664631e-01 | 0.015 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 9.671766e-01 | 0.014 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.671766e-01 | 0.014 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 9.671766e-01 | 0.014 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.671766e-01 | 0.014 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.684355e-01 | 0.014 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.693635e-01 | 0.014 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 9.713725e-01 | 0.013 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 9.713725e-01 | 0.013 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 9.713725e-01 | 0.013 | 0 | 0 |
| Biosynthesis of E-series 18(S)-resolvins | R-HSA-9018896 | 9.713725e-01 | 0.013 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 9.713725e-01 | 0.013 | 0 | 0 |
| Abacavir metabolism | R-HSA-2161541 | 9.713725e-01 | 0.013 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 9.713725e-01 | 0.013 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.721827e-01 | 0.012 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.723466e-01 | 0.012 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.727046e-01 | 0.012 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 9.750323e-01 | 0.011 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 9.750323e-01 | 0.011 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 9.750323e-01 | 0.011 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.750323e-01 | 0.011 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.750323e-01 | 0.011 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 9.754064e-01 | 0.011 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.756925e-01 | 0.011 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.756925e-01 | 0.011 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.778462e-01 | 0.010 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.782244e-01 | 0.010 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 9.782244e-01 | 0.010 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 9.782244e-01 | 0.010 | 0 | 0 |
| Biosynthesis of D-series resolvins | R-HSA-9018676 | 9.782244e-01 | 0.010 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.782244e-01 | 0.010 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.782244e-01 | 0.010 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.782244e-01 | 0.010 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.782244e-01 | 0.010 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.782244e-01 | 0.010 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.783627e-01 | 0.010 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.783627e-01 | 0.010 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.783627e-01 | 0.010 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.807477e-01 | 0.008 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.810085e-01 | 0.008 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.810085e-01 | 0.008 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.810789e-01 | 0.008 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.820514e-01 | 0.008 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.827785e-01 | 0.008 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.827785e-01 | 0.008 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.834368e-01 | 0.007 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.834368e-01 | 0.007 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 9.834368e-01 | 0.007 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.834368e-01 | 0.007 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.838564e-01 | 0.007 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.838564e-01 | 0.007 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.844727e-01 | 0.007 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.847762e-01 | 0.007 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.847762e-01 | 0.007 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.854867e-01 | 0.006 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.855548e-01 | 0.006 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.855548e-01 | 0.006 | 0 | 0 |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | R-HSA-9027604 | 9.855548e-01 | 0.006 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.855548e-01 | 0.006 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 9.855548e-01 | 0.006 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.855548e-01 | 0.006 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.855548e-01 | 0.006 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.856673e-01 | 0.006 | 0 | 0 |
| Linoleic acid (LA) metabolism | R-HSA-2046105 | 9.874020e-01 | 0.006 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 9.874020e-01 | 0.006 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.876357e-01 | 0.005 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.881172e-01 | 0.005 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.890131e-01 | 0.005 | 0 | 0 |
| Biosynthesis of DPAn-3 SPMs | R-HSA-9025094 | 9.890131e-01 | 0.005 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.890131e-01 | 0.005 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.890131e-01 | 0.005 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.893247e-01 | 0.005 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.894832e-01 | 0.005 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.895830e-01 | 0.005 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.904182e-01 | 0.004 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.904182e-01 | 0.004 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.904182e-01 | 0.004 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.905223e-01 | 0.004 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.910230e-01 | 0.004 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.916438e-01 | 0.004 | 0 | 0 |
| Biosynthesis of EPA-derived SPMs | R-HSA-9018679 | 9.916438e-01 | 0.004 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.922785e-01 | 0.003 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.924481e-01 | 0.003 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.924714e-01 | 0.003 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 9.927126e-01 | 0.003 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.933803e-01 | 0.003 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.933803e-01 | 0.003 | 0 | 0 |
| Biosynthesis of DPA-derived SPMs | R-HSA-9018683 | 9.936448e-01 | 0.003 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.936448e-01 | 0.003 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.939026e-01 | 0.003 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.943178e-01 | 0.002 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.945387e-01 | 0.002 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.948101e-01 | 0.002 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.951102e-01 | 0.002 | 0 | 0 |
| Defective B3GALTL causes PpS | R-HSA-5083635 | 9.951668e-01 | 0.002 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.953886e-01 | 0.002 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.953922e-01 | 0.002 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.956234e-01 | 0.002 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.956570e-01 | 0.002 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.957851e-01 | 0.002 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.957851e-01 | 0.002 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.958332e-01 | 0.002 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.961126e-01 | 0.002 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.964050e-01 | 0.002 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.964298e-01 | 0.002 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.964298e-01 | 0.002 | 0 | 0 |
| Translation | R-HSA-72766 | 9.967160e-01 | 0.001 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.967947e-01 | 0.001 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.967947e-01 | 0.001 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.967947e-01 | 0.001 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 9.967947e-01 | 0.001 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.969546e-01 | 0.001 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.970454e-01 | 0.001 | 0 | 0 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 9.971628e-01 | 0.001 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 9.971628e-01 | 0.001 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 9.972048e-01 | 0.001 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 9.972048e-01 | 0.001 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.972048e-01 | 0.001 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.974000e-01 | 0.001 | 0 | 0 |
| O-glycosylation of TSR domain-containing proteins | R-HSA-5173214 | 9.975625e-01 | 0.001 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.975625e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.975625e-01 | 0.001 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.975625e-01 | 0.001 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.975625e-01 | 0.001 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.975625e-01 | 0.001 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.977654e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.977654e-01 | 0.001 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.978745e-01 | 0.001 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.980044e-01 | 0.001 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.980047e-01 | 0.001 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.980714e-01 | 0.001 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.981465e-01 | 0.001 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.983837e-01 | 0.001 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.983837e-01 | 0.001 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.983837e-01 | 0.001 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.984134e-01 | 0.001 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.985811e-01 | 0.001 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.985811e-01 | 0.001 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.985906e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.986403e-01 | 0.001 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.987710e-01 | 0.001 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.989377e-01 | 0.000 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.990613e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.991030e-01 | 0.000 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.991707e-01 | 0.000 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.991852e-01 | 0.000 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.991852e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.993215e-01 | 0.000 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.993518e-01 | 0.000 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.993805e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.994287e-01 | 0.000 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.994598e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.994673e-01 | 0.000 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.995118e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.995119e-01 | 0.000 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.995548e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.995868e-01 | 0.000 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.995893e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.997301e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.997784e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.997901e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.997901e-01 | 0.000 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.997930e-01 | 0.000 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.998427e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.998718e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.998734e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999015e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999326e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.999398e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999432e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.999475e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999539e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999540e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999629e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.999652e-01 | 0.000 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.999652e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999769e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999769e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.999799e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999802e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.999847e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.999847e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999913e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.999923e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999933e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.999933e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999941e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999946e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999978e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999979e-01 | 0.000 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.999981e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999985e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999988e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999989e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999989e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999990e-01 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.999993e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999993e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999994e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999995e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999996e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999997e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999998e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999999e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999999e-01 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 9.999999e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 1.000000e+00 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| M Phase | R-HSA-68886 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 3.230749e-14 | 13.491 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 3.919087e-13 | 12.407 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 2.168377e-12 | 11.664 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 2.168377e-12 | 11.664 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 3.117395e-12 | 11.506 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 6.275314e-12 | 11.202 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.086664e-11 | 10.964 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.762957e-11 | 10.559 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 3.744050e-11 | 10.427 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.961853e-11 | 10.402 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 8.913881e-11 | 10.050 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 8.538359e-11 | 10.069 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.273460e-11 | 10.033 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.012557e-10 | 9.995 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 1.145931e-10 | 9.941 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.338675e-10 | 9.873 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.329845e-10 | 9.876 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.556543e-10 | 9.808 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.671774e-10 | 9.777 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.861461e-10 | 9.730 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 2.125162e-10 | 9.673 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 2.244537e-10 | 9.649 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 3.285299e-10 | 9.483 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 3.597437e-10 | 9.444 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 3.597437e-10 | 9.444 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 4.140941e-10 | 9.383 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 4.739694e-10 | 9.324 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 5.839694e-10 | 9.234 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 5.978787e-10 | 9.223 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 6.954162e-10 | 9.158 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 7.462472e-10 | 9.127 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.242713e-09 | 8.906 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.355071e-09 | 8.868 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.356152e-09 | 8.868 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.575816e-09 | 8.802 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.705789e-09 | 8.768 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 2.049723e-09 | 8.688 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 2.114857e-09 | 8.675 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 3.410415e-09 | 8.467 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 3.930755e-09 | 8.406 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 5.333386e-09 | 8.273 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 6.107863e-09 | 8.214 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 6.396210e-09 | 8.194 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 7.378088e-09 | 8.132 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 9.750943e-09 | 8.011 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.044170e-08 | 7.981 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.077354e-08 | 7.968 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.271421e-08 | 7.896 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.662249e-08 | 7.779 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.784204e-08 | 7.749 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.801502e-08 | 7.744 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.838616e-08 | 7.736 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 2.205507e-08 | 7.656 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 2.455270e-08 | 7.610 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 3.246679e-08 | 7.489 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 3.827246e-08 | 7.417 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 3.984713e-08 | 7.400 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 4.850590e-08 | 7.314 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 5.193464e-08 | 7.285 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 5.981808e-08 | 7.223 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 6.564805e-08 | 7.183 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 6.564805e-08 | 7.183 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 7.135972e-08 | 7.147 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 7.259195e-08 | 7.139 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 8.119893e-08 | 7.090 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 9.160540e-08 | 7.038 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 9.397886e-08 | 7.027 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 8.981674e-08 | 7.047 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.031495e-07 | 6.987 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.209070e-07 | 6.918 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.249962e-07 | 6.903 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.269592e-07 | 6.896 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.278916e-07 | 6.893 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.377188e-07 | 6.861 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.404888e-07 | 6.852 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.584548e-07 | 6.800 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.584548e-07 | 6.800 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.636559e-07 | 6.786 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 1.835107e-07 | 6.736 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.821461e-07 | 6.740 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 1.984495e-07 | 6.702 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 2.118724e-07 | 6.674 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 2.528762e-07 | 6.597 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.506253e-07 | 6.601 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 2.587125e-07 | 6.587 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 2.612356e-07 | 6.583 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 2.785741e-07 | 6.555 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 3.378293e-07 | 6.471 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 3.553108e-07 | 6.449 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 3.420600e-07 | 6.466 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.901941e-07 | 6.310 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 5.612884e-07 | 6.251 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 5.749543e-07 | 6.240 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 5.930033e-07 | 6.227 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 6.233748e-07 | 6.205 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 6.864138e-07 | 6.163 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 7.734726e-07 | 6.112 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 7.898149e-07 | 6.102 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 7.921492e-07 | 6.101 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 8.030378e-07 | 6.095 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 8.995577e-07 | 6.046 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 1.029785e-06 | 5.987 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 1.029785e-06 | 5.987 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.067504e-06 | 5.972 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 1.167056e-06 | 5.933 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.188510e-06 | 5.925 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 1.278628e-06 | 5.893 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.334115e-06 | 5.875 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.380522e-06 | 5.860 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.490149e-06 | 5.827 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 1.423841e-06 | 5.847 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.423841e-06 | 5.847 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.659963e-06 | 5.780 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 1.714114e-06 | 5.766 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.774981e-06 | 5.751 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.783254e-06 | 5.749 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 2.317047e-06 | 5.635 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 2.146077e-06 | 5.668 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 2.198708e-06 | 5.658 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 2.157470e-06 | 5.666 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.410122e-06 | 5.618 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 2.543054e-06 | 5.595 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 2.943740e-06 | 5.531 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 3.068616e-06 | 5.513 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 3.141824e-06 | 5.503 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 3.317101e-06 | 5.479 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 4.225439e-06 | 5.374 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 4.264794e-06 | 5.370 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 4.720907e-06 | 5.326 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 5.619633e-06 | 5.250 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 5.807407e-06 | 5.236 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 5.813686e-06 | 5.236 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 6.173485e-06 | 5.209 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 6.779291e-06 | 5.169 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 6.939414e-06 | 5.159 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 6.959566e-06 | 5.157 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 7.127131e-06 | 5.147 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 7.301677e-06 | 5.137 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 7.301677e-06 | 5.137 | 0 | 0 |
| Kinesins | R-HSA-983189 | 8.350792e-06 | 5.078 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 8.581978e-06 | 5.066 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 9.736157e-06 | 5.012 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 9.442720e-06 | 5.025 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 1.058660e-05 | 4.975 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.060379e-05 | 4.975 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 1.065587e-05 | 4.972 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.068231e-05 | 4.971 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.138434e-05 | 4.944 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.173486e-05 | 4.931 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 1.251131e-05 | 4.903 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.252560e-05 | 4.902 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 1.304672e-05 | 4.884 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 1.368780e-05 | 4.864 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.386974e-05 | 4.858 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.510401e-05 | 4.821 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.518872e-05 | 4.818 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.483588e-05 | 4.829 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 1.506559e-05 | 4.822 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 1.601357e-05 | 4.796 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 1.802498e-05 | 4.744 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 1.849429e-05 | 4.733 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 2.053424e-05 | 4.688 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 2.097856e-05 | 4.678 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 2.131784e-05 | 4.671 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 2.353369e-05 | 4.628 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.586317e-05 | 4.587 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 2.640776e-05 | 4.578 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 2.765127e-05 | 4.558 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.867388e-05 | 4.543 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 3.263755e-05 | 4.486 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 3.381896e-05 | 4.471 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.719339e-05 | 4.430 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 3.769550e-05 | 4.424 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 3.981058e-05 | 4.400 | 0 | 0 |
| S Phase | R-HSA-69242 | 4.905430e-05 | 4.309 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 4.940628e-05 | 4.306 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 4.959489e-05 | 4.305 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 4.812960e-05 | 4.318 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 5.013515e-05 | 4.300 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 5.013515e-05 | 4.300 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 5.013515e-05 | 4.300 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 5.219643e-05 | 4.282 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 5.223682e-05 | 4.282 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 5.245086e-05 | 4.280 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 5.785438e-05 | 4.238 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 5.894271e-05 | 4.230 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 5.997318e-05 | 4.222 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 5.997318e-05 | 4.222 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 6.218903e-05 | 4.206 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 6.717179e-05 | 4.173 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 6.981840e-05 | 4.156 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 7.143673e-05 | 4.146 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 8.490520e-05 | 4.071 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 8.490520e-05 | 4.071 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 7.628583e-05 | 4.118 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 7.628583e-05 | 4.118 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 7.628583e-05 | 4.118 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 7.628583e-05 | 4.118 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 8.311701e-05 | 4.080 | 0 | 0 |
| Translation | R-HSA-72766 | 8.376272e-05 | 4.077 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.963969e-05 | 4.047 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 9.779660e-05 | 4.010 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 9.904860e-05 | 4.004 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.143782e-04 | 3.942 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 1.191448e-04 | 3.924 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.192776e-04 | 3.923 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 1.216697e-04 | 3.915 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.238127e-04 | 3.907 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 1.238127e-04 | 3.907 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.318958e-04 | 3.880 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 1.365216e-04 | 3.865 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 1.372421e-04 | 3.863 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.520852e-04 | 3.818 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.541206e-04 | 3.812 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 1.711505e-04 | 3.767 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 1.896844e-04 | 3.722 | 0 | 0 |
| Protein folding | R-HSA-391251 | 2.175265e-04 | 3.662 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.185601e-04 | 3.660 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 2.185601e-04 | 3.660 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 2.326107e-04 | 3.633 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 2.416385e-04 | 3.617 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 2.451634e-04 | 3.611 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.507591e-04 | 3.601 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.507591e-04 | 3.601 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.615492e-04 | 3.582 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 2.835895e-04 | 3.547 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 2.835895e-04 | 3.547 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 3.215523e-04 | 3.493 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 3.228083e-04 | 3.491 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 3.297293e-04 | 3.482 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 3.297293e-04 | 3.482 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 3.297293e-04 | 3.482 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 3.682478e-04 | 3.434 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 3.877407e-04 | 3.411 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 3.916202e-04 | 3.407 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 4.501556e-04 | 3.347 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 5.128174e-04 | 3.290 | 0 | 0 |
| Depurination | R-HSA-73927 | 5.469081e-04 | 3.262 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 5.535414e-04 | 3.257 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 5.738566e-04 | 3.241 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 5.885714e-04 | 3.230 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 6.096537e-04 | 3.215 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 6.406313e-04 | 3.193 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 6.516222e-04 | 3.186 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 6.731764e-04 | 3.172 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 6.854617e-04 | 3.164 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 6.862440e-04 | 3.164 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 6.862440e-04 | 3.164 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 7.156559e-04 | 3.145 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 7.229295e-04 | 3.141 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 7.234051e-04 | 3.141 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 7.493121e-04 | 3.125 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 7.683004e-04 | 3.114 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 7.926296e-04 | 3.101 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 9.200392e-04 | 3.036 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 9.200392e-04 | 3.036 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.477498e-04 | 3.023 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 8.341864e-04 | 3.079 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 9.821880e-04 | 3.008 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.842483e-04 | 3.007 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 9.896783e-04 | 3.005 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 9.200392e-04 | 3.036 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 9.200392e-04 | 3.036 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 9.660250e-04 | 3.015 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 9.842483e-04 | 3.007 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 9.879184e-04 | 3.005 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 9.933692e-04 | 3.003 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.013224e-03 | 2.994 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 1.043940e-03 | 2.981 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 1.076303e-03 | 2.968 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 1.090877e-03 | 2.962 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 1.094071e-03 | 2.961 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.094071e-03 | 2.961 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.107124e-03 | 2.956 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 1.126767e-03 | 2.948 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 1.164919e-03 | 2.934 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.174245e-03 | 2.930 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 1.177404e-03 | 2.929 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.269670e-03 | 2.896 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.269670e-03 | 2.896 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 1.271901e-03 | 2.896 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.272221e-03 | 2.895 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 1.295999e-03 | 2.887 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.295999e-03 | 2.887 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.332016e-03 | 2.875 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.332016e-03 | 2.875 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.332016e-03 | 2.875 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.458331e-03 | 2.836 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.470151e-03 | 2.833 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 1.491135e-03 | 2.826 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.491135e-03 | 2.826 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.516792e-03 | 2.819 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.653235e-03 | 2.782 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.725476e-03 | 2.763 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.725476e-03 | 2.763 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 1.836849e-03 | 2.736 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.856836e-03 | 2.731 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 2.056762e-03 | 2.687 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.091409e-03 | 2.680 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 2.091409e-03 | 2.680 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 2.131674e-03 | 2.671 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 2.132507e-03 | 2.671 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.222922e-03 | 2.653 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 2.230381e-03 | 2.652 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 2.264845e-03 | 2.645 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 2.287711e-03 | 2.641 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 2.336613e-03 | 2.631 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 2.336613e-03 | 2.631 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 2.405603e-03 | 2.619 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 2.405603e-03 | 2.619 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 2.595885e-03 | 2.586 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 2.896298e-03 | 2.538 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 2.896298e-03 | 2.538 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 2.879468e-03 | 2.541 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.908509e-03 | 2.536 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 2.937133e-03 | 2.532 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 3.060975e-03 | 2.514 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 2.592655e-03 | 2.586 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 2.508852e-03 | 2.601 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 2.595885e-03 | 2.586 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 3.064550e-03 | 2.514 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 2.914689e-03 | 2.535 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 3.084832e-03 | 2.511 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 3.103298e-03 | 2.508 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 3.150335e-03 | 2.502 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.150335e-03 | 2.502 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 3.318239e-03 | 2.479 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 3.332748e-03 | 2.477 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 3.332748e-03 | 2.477 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 3.332748e-03 | 2.477 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 3.367884e-03 | 2.473 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.422361e-03 | 2.466 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 3.424788e-03 | 2.465 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 3.440251e-03 | 2.463 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 3.440251e-03 | 2.463 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 3.440251e-03 | 2.463 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 3.479006e-03 | 2.459 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 3.587566e-03 | 2.445 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.704910e-03 | 2.431 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 3.747229e-03 | 2.426 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 3.747229e-03 | 2.426 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 3.809484e-03 | 2.419 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 3.809484e-03 | 2.419 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 3.812406e-03 | 2.419 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.852909e-03 | 2.414 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 3.905787e-03 | 2.408 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 3.912136e-03 | 2.408 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 3.918407e-03 | 2.407 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 3.969775e-03 | 2.401 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 4.027102e-03 | 2.395 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 4.118508e-03 | 2.385 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 4.572883e-03 | 2.340 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 4.572883e-03 | 2.340 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 4.651492e-03 | 2.332 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 4.662219e-03 | 2.331 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 4.662219e-03 | 2.331 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 4.662219e-03 | 2.331 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 4.669592e-03 | 2.331 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 4.710139e-03 | 2.327 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 4.710139e-03 | 2.327 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 4.749537e-03 | 2.323 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 4.863075e-03 | 2.313 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.899628e-03 | 2.310 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.899628e-03 | 2.310 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.899628e-03 | 2.310 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.899628e-03 | 2.310 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 4.958601e-03 | 2.305 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 4.958601e-03 | 2.305 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 4.958601e-03 | 2.305 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 4.958601e-03 | 2.305 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 4.958601e-03 | 2.305 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 4.967083e-03 | 2.304 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 5.183531e-03 | 2.285 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 5.183531e-03 | 2.285 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 5.224831e-03 | 2.282 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 5.273166e-03 | 2.278 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.293365e-03 | 2.276 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 5.901025e-03 | 2.229 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 5.901025e-03 | 2.229 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 5.901025e-03 | 2.229 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 7.088831e-03 | 2.149 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 7.088831e-03 | 2.149 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 6.347162e-03 | 2.197 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 6.347162e-03 | 2.197 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 5.642684e-03 | 2.249 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 6.389230e-03 | 2.195 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 7.086426e-03 | 2.150 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 7.086426e-03 | 2.150 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 5.841336e-03 | 2.233 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 5.901025e-03 | 2.229 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 5.901025e-03 | 2.229 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 5.514343e-03 | 2.259 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 5.780870e-03 | 2.238 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 6.569022e-03 | 2.182 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 6.488065e-03 | 2.188 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 7.073229e-03 | 2.150 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 6.282949e-03 | 2.202 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 5.642684e-03 | 2.249 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 6.176269e-03 | 2.209 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 5.901025e-03 | 2.229 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 7.211690e-03 | 2.142 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 7.218001e-03 | 2.142 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 7.316039e-03 | 2.136 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 7.316039e-03 | 2.136 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 7.356354e-03 | 2.133 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 7.356354e-03 | 2.133 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 7.459684e-03 | 2.127 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 7.490223e-03 | 2.126 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 7.490223e-03 | 2.126 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 7.564484e-03 | 2.121 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 7.564484e-03 | 2.121 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 7.564484e-03 | 2.121 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 7.579912e-03 | 2.120 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 7.914161e-03 | 2.102 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 8.395357e-03 | 2.076 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 8.395357e-03 | 2.076 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.604095e-03 | 2.065 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 8.604095e-03 | 2.065 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 8.806574e-03 | 2.055 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 8.998096e-03 | 2.046 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 8.998096e-03 | 2.046 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 9.045429e-03 | 2.044 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 9.335283e-03 | 2.030 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 9.366954e-03 | 2.028 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 9.592914e-03 | 2.018 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.592914e-03 | 2.018 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 9.592914e-03 | 2.018 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 9.887844e-03 | 2.005 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 9.972678e-03 | 2.001 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.017799e-02 | 1.992 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 1.017799e-02 | 1.992 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 1.017799e-02 | 1.992 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.018587e-02 | 1.992 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.022851e-02 | 1.990 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 1.034458e-02 | 1.985 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 1.050058e-02 | 1.979 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 1.050058e-02 | 1.979 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.091658e-02 | 1.962 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 1.108108e-02 | 1.955 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 1.140073e-02 | 1.943 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 1.205139e-02 | 1.919 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 1.205139e-02 | 1.919 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 1.205139e-02 | 1.919 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.208795e-02 | 1.918 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 1.208795e-02 | 1.918 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.214144e-02 | 1.916 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 1.225053e-02 | 1.912 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.225053e-02 | 1.912 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 1.225053e-02 | 1.912 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.237428e-02 | 1.907 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 1.237428e-02 | 1.907 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 1.237428e-02 | 1.907 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.259026e-02 | 1.900 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.260174e-02 | 1.900 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 1.265090e-02 | 1.898 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 1.339493e-02 | 1.873 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 1.339493e-02 | 1.873 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.354519e-02 | 1.868 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.408528e-02 | 1.851 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 1.420560e-02 | 1.848 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.420560e-02 | 1.848 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.457151e-02 | 1.836 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 1.458192e-02 | 1.836 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 1.458192e-02 | 1.836 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 1.458192e-02 | 1.836 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.464348e-02 | 1.834 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.521437e-02 | 1.818 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 1.572332e-02 | 1.803 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 1.572332e-02 | 1.803 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.572332e-02 | 1.803 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 1.577098e-02 | 1.802 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 2.184812e-02 | 1.661 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.327818e-02 | 1.633 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 2.024881e-02 | 1.694 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.990505e-02 | 1.701 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.878105e-02 | 1.726 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 2.142548e-02 | 1.669 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 2.364681e-02 | 1.626 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 1.925535e-02 | 1.715 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 2.392622e-02 | 1.621 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 2.282991e-02 | 1.641 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 1.955313e-02 | 1.709 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.763033e-02 | 1.754 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 2.148689e-02 | 1.668 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 1.988016e-02 | 1.702 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 2.126742e-02 | 1.672 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 2.126742e-02 | 1.672 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 1.658239e-02 | 1.780 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 1.955313e-02 | 1.709 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 2.169817e-02 | 1.664 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.935983e-02 | 1.713 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 2.265392e-02 | 1.645 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.935983e-02 | 1.713 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 1.899126e-02 | 1.721 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 1.985410e-02 | 1.702 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 1.935983e-02 | 1.713 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 1.899126e-02 | 1.721 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 2.121013e-02 | 1.673 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.878105e-02 | 1.726 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.889295e-02 | 1.724 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 2.199940e-02 | 1.658 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.720747e-02 | 1.764 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 2.392622e-02 | 1.621 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.736708e-02 | 1.760 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 1.730983e-02 | 1.762 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 2.327818e-02 | 1.633 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 2.199940e-02 | 1.658 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 2.148689e-02 | 1.668 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 2.432294e-02 | 1.614 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.432294e-02 | 1.614 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 2.432294e-02 | 1.614 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 2.437254e-02 | 1.613 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 2.465755e-02 | 1.608 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 2.500214e-02 | 1.602 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 2.500214e-02 | 1.602 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 2.500214e-02 | 1.602 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 2.500214e-02 | 1.602 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 2.681569e-02 | 1.572 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 2.681569e-02 | 1.572 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 2.748410e-02 | 1.561 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 2.802561e-02 | 1.552 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 2.802561e-02 | 1.552 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.802561e-02 | 1.552 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.802561e-02 | 1.552 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.802561e-02 | 1.552 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 2.814476e-02 | 1.551 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.829283e-02 | 1.548 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 2.830331e-02 | 1.548 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 2.979054e-02 | 1.526 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 3.024683e-02 | 1.519 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 3.024683e-02 | 1.519 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 3.052189e-02 | 1.515 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 3.091896e-02 | 1.510 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.223454e-02 | 1.492 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.256296e-02 | 1.487 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 3.256296e-02 | 1.487 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 3.272620e-02 | 1.485 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 3.361151e-02 | 1.474 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 3.367949e-02 | 1.473 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 3.398644e-02 | 1.469 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 3.398644e-02 | 1.469 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 3.418295e-02 | 1.466 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.463675e-02 | 1.460 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 3.511881e-02 | 1.454 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 3.645128e-02 | 1.438 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 3.714462e-02 | 1.430 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 3.755193e-02 | 1.425 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 3.755193e-02 | 1.425 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 3.757290e-02 | 1.425 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 3.757290e-02 | 1.425 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 3.757290e-02 | 1.425 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 3.757290e-02 | 1.425 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.810451e-02 | 1.419 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.885254e-02 | 1.411 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 3.885254e-02 | 1.411 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 4.291744e-02 | 1.367 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 4.295403e-02 | 1.367 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 4.297356e-02 | 1.367 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 4.330373e-02 | 1.363 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 4.369984e-02 | 1.360 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 4.369984e-02 | 1.360 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 4.369984e-02 | 1.360 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 4.369984e-02 | 1.360 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 4.390787e-02 | 1.357 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.514523e-02 | 1.345 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 4.514523e-02 | 1.345 | 0 | 0 |
| Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) | R-HSA-1299308 | 4.514523e-02 | 1.345 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 4.550104e-02 | 1.342 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 4.622704e-02 | 1.335 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 4.640406e-02 | 1.333 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 4.640406e-02 | 1.333 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 4.694086e-02 | 1.328 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 4.735269e-02 | 1.325 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 4.735269e-02 | 1.325 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 4.735269e-02 | 1.325 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 4.735269e-02 | 1.325 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 4.735269e-02 | 1.325 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 4.735269e-02 | 1.325 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 4.735269e-02 | 1.325 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 4.756770e-02 | 1.323 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 4.756770e-02 | 1.323 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 4.892062e-02 | 1.311 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 4.982310e-02 | 1.303 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 5.103210e-02 | 1.292 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 5.125658e-02 | 1.290 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 5.152094e-02 | 1.288 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 5.249263e-02 | 1.280 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 5.249263e-02 | 1.280 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 5.313417e-02 | 1.275 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 5.313417e-02 | 1.275 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 5.313417e-02 | 1.275 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 5.374725e-02 | 1.270 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 5.374725e-02 | 1.270 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 5.442471e-02 | 1.264 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 5.447236e-02 | 1.264 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 5.483308e-02 | 1.261 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 5.503989e-02 | 1.259 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 5.532889e-02 | 1.257 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 5.532889e-02 | 1.257 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 5.532889e-02 | 1.257 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 5.535398e-02 | 1.257 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 5.663412e-02 | 1.247 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 5.751965e-02 | 1.240 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.773351e-02 | 1.239 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 5.936030e-02 | 1.227 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 5.990992e-02 | 1.223 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 5.990992e-02 | 1.223 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 5.990992e-02 | 1.223 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 6.050527e-02 | 1.218 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 6.050527e-02 | 1.218 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 6.050527e-02 | 1.218 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 6.172557e-02 | 1.210 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 6.172557e-02 | 1.210 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 6.172557e-02 | 1.210 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 6.181152e-02 | 1.209 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 6.221214e-02 | 1.206 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 6.221214e-02 | 1.206 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 6.329400e-02 | 1.199 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 6.470281e-02 | 1.189 | 0 | 0 |
| Immune System | R-HSA-168256 | 6.529911e-02 | 1.185 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 6.661300e-02 | 1.176 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 6.681762e-02 | 1.175 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 6.681762e-02 | 1.175 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 6.682715e-02 | 1.175 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 6.957838e-02 | 1.158 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 6.995672e-02 | 1.155 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 7.033634e-02 | 1.153 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 7.033634e-02 | 1.153 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 7.033634e-02 | 1.153 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 7.033634e-02 | 1.153 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 7.363631e-02 | 1.133 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 7.363631e-02 | 1.133 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 7.372463e-02 | 1.132 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 7.538330e-02 | 1.123 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 7.566937e-02 | 1.121 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.544815e-01 | 0.811 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.544815e-01 | 0.811 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.544815e-01 | 0.811 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.544815e-01 | 0.811 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.544815e-01 | 0.811 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.544815e-01 | 0.811 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.544815e-01 | 0.811 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.544815e-01 | 0.811 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 1.544815e-01 | 0.811 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 9.120396e-02 | 1.040 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 9.120396e-02 | 1.040 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 9.120396e-02 | 1.040 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 9.120396e-02 | 1.040 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.177022e-01 | 0.929 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 1.177022e-01 | 0.929 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.177022e-01 | 0.929 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 8.148210e-02 | 1.089 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 8.148210e-02 | 1.089 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 1.458231e-01 | 0.836 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 1.458231e-01 | 0.836 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.458231e-01 | 0.836 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.458231e-01 | 0.836 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 9.763783e-02 | 1.010 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 1.149676e-01 | 0.939 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 8.979785e-02 | 1.047 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 8.979785e-02 | 1.047 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 1.333532e-01 | 0.875 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 1.025303e-01 | 0.989 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 1.025303e-01 | 0.989 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 1.025303e-01 | 0.989 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 1.526739e-01 | 0.816 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 1.526739e-01 | 0.816 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 1.526739e-01 | 0.816 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.526739e-01 | 0.816 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 1.526739e-01 | 0.816 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 1.526739e-01 | 0.816 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 7.957263e-02 | 1.099 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 1.160381e-01 | 0.935 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.160381e-01 | 0.935 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 8.942356e-02 | 1.049 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 1.302758e-01 | 0.885 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.302758e-01 | 0.885 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 1.302758e-01 | 0.885 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 8.575266e-02 | 1.067 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 1.451939e-01 | 0.838 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 9.455123e-02 | 1.024 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 9.455123e-02 | 1.024 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.135309e-01 | 0.945 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 1.472750e-01 | 0.832 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 1.472750e-01 | 0.832 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 9.594610e-02 | 1.018 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.452760e-01 | 0.838 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 1.342772e-01 | 0.872 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 8.575266e-02 | 1.067 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 1.452760e-01 | 0.838 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 8.831880e-02 | 1.054 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 9.447442e-02 | 1.025 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 7.788183e-02 | 1.109 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 7.788183e-02 | 1.109 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.346328e-01 | 0.871 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.045335e-01 | 0.981 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 1.177022e-01 | 0.929 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 8.942356e-02 | 1.049 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 8.148210e-02 | 1.089 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 1.472750e-01 | 0.832 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 1.177022e-01 | 0.929 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 7.788183e-02 | 1.109 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 9.455123e-02 | 1.024 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.132031e-01 | 0.946 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.112559e-01 | 0.954 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.526739e-01 | 0.816 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 8.191423e-02 | 1.087 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.233965e-01 | 0.909 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.233965e-01 | 0.909 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.233965e-01 | 0.909 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.233965e-01 | 0.909 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 1.025303e-01 | 0.989 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 1.160381e-01 | 0.935 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 8.575266e-02 | 1.067 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 8.191423e-02 | 1.087 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 1.225016e-01 | 0.912 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 1.524831e-01 | 0.817 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 1.216937e-01 | 0.915 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 1.524831e-01 | 0.817 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.458231e-01 | 0.836 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.050143e-01 | 0.979 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 7.742641e-02 | 1.111 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 1.132031e-01 | 0.946 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.034429e-01 | 0.985 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.135309e-01 | 0.945 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.544815e-01 | 0.811 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 9.120396e-02 | 1.040 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 9.120396e-02 | 1.040 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 9.120396e-02 | 1.040 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 1.177022e-01 | 0.929 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 1.149676e-01 | 0.939 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 1.160381e-01 | 0.935 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 8.831880e-02 | 1.054 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.342767e-01 | 0.872 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.414799e-01 | 0.849 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.233965e-01 | 0.909 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 9.485354e-02 | 1.023 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.411214e-01 | 0.850 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 8.876901e-02 | 1.052 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.181014e-01 | 0.928 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.025303e-01 | 0.989 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 1.458231e-01 | 0.836 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.458231e-01 | 0.836 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 1.236898e-01 | 0.908 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 9.228411e-02 | 1.035 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 7.908117e-02 | 1.102 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 1.346328e-01 | 0.871 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 7.788183e-02 | 1.109 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.084652e-01 | 0.965 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 9.120396e-02 | 1.040 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 1.177022e-01 | 0.929 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 1.135309e-01 | 0.945 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 9.447442e-02 | 1.025 | 0 | 0 |
| Disease | R-HSA-1643685 | 1.127953e-01 | 0.948 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 1.452760e-01 | 0.838 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 1.342767e-01 | 0.872 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 8.698125e-02 | 1.061 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 1.034429e-01 | 0.985 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 1.135309e-01 | 0.945 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 7.788183e-02 | 1.109 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 1.302758e-01 | 0.885 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.109076e-01 | 0.955 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.109076e-01 | 0.955 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 9.987454e-02 | 1.001 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 8.078427e-02 | 1.093 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 1.312958e-01 | 0.882 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 7.957263e-02 | 1.099 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.135309e-01 | 0.945 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 1.472750e-01 | 0.832 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.987454e-02 | 1.001 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 1.139178e-01 | 0.943 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.025303e-01 | 0.989 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 7.788183e-02 | 1.109 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 1.007374e-01 | 0.997 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 8.979785e-02 | 1.047 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.160381e-01 | 0.935 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 1.177022e-01 | 0.929 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 1.566705e-01 | 0.805 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 1.566705e-01 | 0.805 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 1.569765e-01 | 0.804 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 1.576066e-01 | 0.802 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.591122e-01 | 0.798 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.603997e-01 | 0.795 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.603997e-01 | 0.795 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 1.603997e-01 | 0.795 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 1.607402e-01 | 0.794 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 1.652921e-01 | 0.782 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.670365e-01 | 0.777 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.725520e-01 | 0.763 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 1.725520e-01 | 0.763 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.725520e-01 | 0.763 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 1.728084e-01 | 0.762 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.728084e-01 | 0.762 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.728084e-01 | 0.762 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 1.734269e-01 | 0.761 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 1.739768e-01 | 0.760 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 1.739768e-01 | 0.760 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 1.739768e-01 | 0.760 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 1.751343e-01 | 0.757 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 1.751343e-01 | 0.757 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 1.751343e-01 | 0.757 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 1.751343e-01 | 0.757 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 1.751343e-01 | 0.757 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 1.751343e-01 | 0.757 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 1.751343e-01 | 0.757 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 1.805704e-01 | 0.743 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.805801e-01 | 0.743 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 1.839145e-01 | 0.735 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.879748e-01 | 0.726 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 1.879748e-01 | 0.726 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.909381e-01 | 0.719 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 1.930353e-01 | 0.714 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 1.930353e-01 | 0.714 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 1.930353e-01 | 0.714 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 1.930353e-01 | 0.714 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.930353e-01 | 0.714 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.934897e-01 | 0.713 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 1.934979e-01 | 0.713 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 1.936371e-01 | 0.713 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 2.023608e-01 | 0.694 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 2.046104e-01 | 0.689 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 2.046104e-01 | 0.689 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 2.046104e-01 | 0.689 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.052625e-01 | 0.688 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 2.052625e-01 | 0.688 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 2.052625e-01 | 0.688 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 2.052625e-01 | 0.688 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.052625e-01 | 0.688 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 2.058149e-01 | 0.687 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 2.105968e-01 | 0.677 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 2.105968e-01 | 0.677 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 2.150433e-01 | 0.667 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.150433e-01 | 0.667 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 2.171011e-01 | 0.663 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 2.191095e-01 | 0.659 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.225342e-01 | 0.653 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 2.225342e-01 | 0.653 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.225342e-01 | 0.653 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 2.225342e-01 | 0.653 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.225342e-01 | 0.653 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.225342e-01 | 0.653 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.225342e-01 | 0.653 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 2.225342e-01 | 0.653 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.225342e-01 | 0.653 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.225342e-01 | 0.653 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.225342e-01 | 0.653 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 2.271617e-01 | 0.644 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 2.280999e-01 | 0.642 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 2.321617e-01 | 0.634 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 2.321617e-01 | 0.634 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.358867e-01 | 0.627 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 2.358867e-01 | 0.627 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 2.358867e-01 | 0.627 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 2.358867e-01 | 0.627 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.364760e-01 | 0.626 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 2.369146e-01 | 0.625 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 2.369146e-01 | 0.625 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.369146e-01 | 0.625 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.369146e-01 | 0.625 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 2.425161e-01 | 0.615 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 2.441221e-01 | 0.612 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 2.443024e-01 | 0.612 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.458152e-01 | 0.609 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 2.459506e-01 | 0.609 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.459506e-01 | 0.609 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 2.475077e-01 | 0.606 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 2.475077e-01 | 0.606 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 2.475077e-01 | 0.606 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 2.591435e-01 | 0.586 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.591435e-01 | 0.586 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 2.591435e-01 | 0.586 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 2.613320e-01 | 0.583 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 2.631046e-01 | 0.580 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 2.631046e-01 | 0.580 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 2.640929e-01 | 0.578 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 2.640929e-01 | 0.578 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 2.640929e-01 | 0.578 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 2.662188e-01 | 0.575 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 2.667322e-01 | 0.574 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.667322e-01 | 0.574 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 2.667322e-01 | 0.574 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 2.667322e-01 | 0.574 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 2.667322e-01 | 0.574 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 2.667322e-01 | 0.574 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.667322e-01 | 0.574 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 2.667322e-01 | 0.574 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 2.667322e-01 | 0.574 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 2.667322e-01 | 0.574 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 2.736322e-01 | 0.563 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 2.736322e-01 | 0.563 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.736322e-01 | 0.563 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 2.736436e-01 | 0.563 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.767792e-01 | 0.558 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 2.816283e-01 | 0.550 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 2.816283e-01 | 0.550 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 2.816283e-01 | 0.550 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 2.824722e-01 | 0.549 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 2.824722e-01 | 0.549 | 0 | 0 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 | R-HSA-5083629 | 2.851134e-01 | 0.545 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 2.851134e-01 | 0.545 | 0 | 0 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 | R-HSA-5083633 | 2.851134e-01 | 0.545 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 2.851134e-01 | 0.545 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 2.851134e-01 | 0.545 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 2.851134e-01 | 0.545 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 2.851134e-01 | 0.545 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 2.851134e-01 | 0.545 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.878140e-01 | 0.541 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 2.878140e-01 | 0.541 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 2.933877e-01 | 0.533 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 2.933877e-01 | 0.533 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 2.949127e-01 | 0.530 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 2.975651e-01 | 0.526 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.975651e-01 | 0.526 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 2.975651e-01 | 0.526 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 2.975651e-01 | 0.526 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 2.975651e-01 | 0.526 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 3.010353e-01 | 0.521 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 3.010353e-01 | 0.521 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 3.010353e-01 | 0.521 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 3.021462e-01 | 0.520 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 3.042737e-01 | 0.517 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 3.042737e-01 | 0.517 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 3.090185e-01 | 0.510 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 3.103933e-01 | 0.508 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 3.129460e-01 | 0.505 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 3.162194e-01 | 0.500 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 3.190572e-01 | 0.496 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 3.197306e-01 | 0.495 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 3.197306e-01 | 0.495 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 3.197306e-01 | 0.495 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 3.228858e-01 | 0.491 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.269905e-01 | 0.485 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 3.269905e-01 | 0.485 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 3.269905e-01 | 0.485 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 3.273140e-01 | 0.485 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 3.281879e-01 | 0.484 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 3.281879e-01 | 0.484 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.281879e-01 | 0.484 | 0 | 0 |
| Regulation of gene expression in early pancreatic precursor cells | R-HSA-210747 | 3.281879e-01 | 0.484 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 3.281879e-01 | 0.484 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.283619e-01 | 0.484 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 3.311666e-01 | 0.480 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 3.329654e-01 | 0.478 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 3.345237e-01 | 0.476 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 3.426589e-01 | 0.465 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 3.426589e-01 | 0.465 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 3.426589e-01 | 0.465 | 0 | 0 |
| Defective ABCC2 causes DJS | R-HSA-5679001 | 3.426589e-01 | 0.465 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.426589e-01 | 0.465 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.426589e-01 | 0.465 | 0 | 0 |
| Inhibition of nitric oxide production | R-HSA-9636249 | 3.426589e-01 | 0.465 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.426589e-01 | 0.465 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 3.426589e-01 | 0.465 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 3.436549e-01 | 0.464 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 3.496965e-01 | 0.456 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 3.496965e-01 | 0.456 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 3.496965e-01 | 0.456 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 3.496965e-01 | 0.456 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 3.496965e-01 | 0.456 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 3.496965e-01 | 0.456 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 3.496965e-01 | 0.456 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 3.564576e-01 | 0.448 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 3.573226e-01 | 0.447 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 3.582429e-01 | 0.446 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 3.584349e-01 | 0.446 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 3.584349e-01 | 0.446 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 3.584349e-01 | 0.446 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 3.584349e-01 | 0.446 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 3.584349e-01 | 0.446 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 3.584349e-01 | 0.446 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 3.584349e-01 | 0.446 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 3.597629e-01 | 0.444 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 3.597629e-01 | 0.444 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.600471e-01 | 0.444 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 3.600471e-01 | 0.444 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 3.600471e-01 | 0.444 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 3.600471e-01 | 0.444 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 3.600471e-01 | 0.444 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 3.707972e-01 | 0.431 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 3.723159e-01 | 0.429 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 3.723159e-01 | 0.429 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 3.728815e-01 | 0.428 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 3.764604e-01 | 0.424 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 3.803410e-01 | 0.420 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 3.881681e-01 | 0.411 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 3.881681e-01 | 0.411 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 3.881681e-01 | 0.411 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.881681e-01 | 0.411 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 3.928654e-01 | 0.406 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 3.955754e-01 | 0.403 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 3.955754e-01 | 0.403 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 3.955754e-01 | 0.403 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 3.955754e-01 | 0.403 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 3.955754e-01 | 0.403 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 3.955754e-01 | 0.403 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 3.955754e-01 | 0.403 | 0 | 0 |
| Toxicity of tetanus toxin (tetX) | R-HSA-5250982 | 3.955754e-01 | 0.403 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 4.092344e-01 | 0.388 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 4.097339e-01 | 0.387 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.135414e-01 | 0.383 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 4.150332e-01 | 0.382 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 4.170254e-01 | 0.380 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 4.172745e-01 | 0.380 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 4.172745e-01 | 0.380 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 4.172745e-01 | 0.380 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 4.172745e-01 | 0.380 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 4.172745e-01 | 0.380 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 4.172745e-01 | 0.380 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 4.172745e-01 | 0.380 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 4.254594e-01 | 0.371 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 4.255406e-01 | 0.371 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 4.317293e-01 | 0.365 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 4.317293e-01 | 0.365 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 4.317293e-01 | 0.365 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 4.320741e-01 | 0.364 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 4.333987e-01 | 0.363 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 4.341070e-01 | 0.362 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 4.359890e-01 | 0.361 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 4.389967e-01 | 0.358 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 4.389967e-01 | 0.358 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 4.389967e-01 | 0.358 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 4.389967e-01 | 0.358 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 4.428001e-01 | 0.354 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 4.442349e-01 | 0.352 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 4.442349e-01 | 0.352 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.442349e-01 | 0.352 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 4.442349e-01 | 0.352 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.442349e-01 | 0.352 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 4.442349e-01 | 0.352 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 4.442349e-01 | 0.352 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 4.442349e-01 | 0.352 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 4.442349e-01 | 0.352 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.442349e-01 | 0.352 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 4.442349e-01 | 0.352 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 4.442349e-01 | 0.352 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 4.442349e-01 | 0.352 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 4.442349e-01 | 0.352 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 4.456623e-01 | 0.351 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 4.456623e-01 | 0.351 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 4.456623e-01 | 0.351 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 4.456623e-01 | 0.351 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 4.504436e-01 | 0.346 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 4.504436e-01 | 0.346 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 4.540358e-01 | 0.343 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 4.551915e-01 | 0.342 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 4.578649e-01 | 0.339 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 4.583113e-01 | 0.339 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 4.606435e-01 | 0.337 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 4.686178e-01 | 0.329 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 4.732586e-01 | 0.325 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 4.732586e-01 | 0.325 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 4.732586e-01 | 0.325 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 4.732586e-01 | 0.325 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 4.738365e-01 | 0.324 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 4.779109e-01 | 0.321 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 4.806005e-01 | 0.318 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 4.819215e-01 | 0.317 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 4.819215e-01 | 0.317 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 4.865676e-01 | 0.313 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 4.865676e-01 | 0.313 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 4.889797e-01 | 0.311 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 4.889797e-01 | 0.311 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 4.889797e-01 | 0.311 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 4.889797e-01 | 0.311 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 4.889797e-01 | 0.311 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 4.889797e-01 | 0.311 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 4.889797e-01 | 0.311 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 4.889797e-01 | 0.311 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 4.889797e-01 | 0.311 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 4.889797e-01 | 0.311 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 4.889797e-01 | 0.311 | 0 | 0 |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors | R-HSA-389397 | 4.889797e-01 | 0.311 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 4.889797e-01 | 0.311 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 4.889797e-01 | 0.311 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 4.889797e-01 | 0.311 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 4.919396e-01 | 0.308 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 4.920121e-01 | 0.308 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 5.000071e-01 | 0.301 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 5.000071e-01 | 0.301 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 5.000071e-01 | 0.301 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 5.000071e-01 | 0.301 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 5.000071e-01 | 0.301 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 5.000071e-01 | 0.301 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 5.000071e-01 | 0.301 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 5.000071e-01 | 0.301 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 5.027919e-01 | 0.299 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 5.089546e-01 | 0.293 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 5.232211e-01 | 0.281 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 5.232211e-01 | 0.281 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 5.258652e-01 | 0.279 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 5.258652e-01 | 0.279 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 5.258652e-01 | 0.279 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 5.258652e-01 | 0.279 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 5.258652e-01 | 0.279 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.301246e-01 | 0.276 | 0 | 0 |
| Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) | R-HSA-5619070 | 5.301246e-01 | 0.276 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 5.301246e-01 | 0.276 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 5.301246e-01 | 0.276 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 5.301246e-01 | 0.276 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.301246e-01 | 0.276 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 5.339935e-01 | 0.272 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 5.339935e-01 | 0.272 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 5.388148e-01 | 0.269 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 5.388148e-01 | 0.269 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 5.431805e-01 | 0.265 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 5.508031e-01 | 0.259 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 5.508031e-01 | 0.259 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 5.508031e-01 | 0.259 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 5.508031e-01 | 0.259 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 5.509896e-01 | 0.259 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 5.541961e-01 | 0.256 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 5.556238e-01 | 0.255 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 5.556238e-01 | 0.255 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 5.594387e-01 | 0.252 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 5.594387e-01 | 0.252 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 5.611936e-01 | 0.251 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 5.626461e-01 | 0.250 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 5.626461e-01 | 0.250 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 5.626461e-01 | 0.250 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 5.626461e-01 | 0.250 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 5.629299e-01 | 0.250 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 5.679590e-01 | 0.246 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 5.679590e-01 | 0.246 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 5.679590e-01 | 0.246 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 5.679590e-01 | 0.246 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 5.679590e-01 | 0.246 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 5.679590e-01 | 0.246 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 5.679590e-01 | 0.246 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 5.679590e-01 | 0.246 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 5.679590e-01 | 0.246 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 5.679590e-01 | 0.246 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 5.679590e-01 | 0.246 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 5.748012e-01 | 0.240 | 0 | 0 |
| PKA activation | R-HSA-163615 | 5.748012e-01 | 0.240 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 5.748012e-01 | 0.240 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 5.748012e-01 | 0.240 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 5.748012e-01 | 0.240 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 5.748012e-01 | 0.240 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 5.748012e-01 | 0.240 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 5.748012e-01 | 0.240 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 5.815981e-01 | 0.235 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 5.815981e-01 | 0.235 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 5.815981e-01 | 0.235 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 5.864155e-01 | 0.232 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 5.882257e-01 | 0.230 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 5.887365e-01 | 0.230 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 5.887365e-01 | 0.230 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 5.896873e-01 | 0.229 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 5.915167e-01 | 0.228 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 5.920515e-01 | 0.228 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 5.978492e-01 | 0.223 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 5.978492e-01 | 0.223 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 5.978492e-01 | 0.223 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 5.978492e-01 | 0.223 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 5.978492e-01 | 0.223 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 5.978492e-01 | 0.223 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 5.978492e-01 | 0.223 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 6.000207e-01 | 0.222 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 6.000207e-01 | 0.222 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 6.027490e-01 | 0.220 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.027490e-01 | 0.220 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.027490e-01 | 0.220 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 6.027490e-01 | 0.220 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 6.027490e-01 | 0.220 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 6.027490e-01 | 0.220 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 6.027490e-01 | 0.220 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 6.027490e-01 | 0.220 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 6.027490e-01 | 0.220 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 6.027490e-01 | 0.220 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 6.027490e-01 | 0.220 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.027490e-01 | 0.220 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 6.027490e-01 | 0.220 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 6.027490e-01 | 0.220 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.027490e-01 | 0.220 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 6.061909e-01 | 0.217 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 6.179017e-01 | 0.209 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 6.199446e-01 | 0.208 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 6.199446e-01 | 0.208 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 6.199446e-01 | 0.208 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 6.199446e-01 | 0.208 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 6.199446e-01 | 0.208 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 6.222187e-01 | 0.206 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 6.224453e-01 | 0.206 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 6.318620e-01 | 0.199 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.347394e-01 | 0.197 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 6.347394e-01 | 0.197 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 6.347394e-01 | 0.197 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 6.347394e-01 | 0.197 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 6.347394e-01 | 0.197 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.347394e-01 | 0.197 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 6.347394e-01 | 0.197 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.347394e-01 | 0.197 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 6.347394e-01 | 0.197 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 6.352323e-01 | 0.197 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 6.352323e-01 | 0.197 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 6.352323e-01 | 0.197 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 6.352323e-01 | 0.197 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 6.352323e-01 | 0.197 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 6.369647e-01 | 0.196 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 6.410913e-01 | 0.193 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 6.410913e-01 | 0.193 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 6.410913e-01 | 0.193 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 6.410913e-01 | 0.193 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 6.410913e-01 | 0.193 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 6.410913e-01 | 0.193 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 6.410913e-01 | 0.193 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 6.490176e-01 | 0.188 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 6.520066e-01 | 0.186 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 6.520066e-01 | 0.186 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 6.593484e-01 | 0.181 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 6.612987e-01 | 0.180 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 6.612987e-01 | 0.180 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 6.615506e-01 | 0.179 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 6.635681e-01 | 0.178 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 6.641554e-01 | 0.178 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 6.641554e-01 | 0.178 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 6.641554e-01 | 0.178 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 6.641554e-01 | 0.178 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 6.641554e-01 | 0.178 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 6.641554e-01 | 0.178 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 6.641554e-01 | 0.178 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 6.641554e-01 | 0.178 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 6.641554e-01 | 0.178 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 6.641554e-01 | 0.178 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 6.641554e-01 | 0.178 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 6.680230e-01 | 0.175 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.682216e-01 | 0.175 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 6.682216e-01 | 0.175 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 6.682216e-01 | 0.175 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 6.682216e-01 | 0.175 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 6.682216e-01 | 0.175 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.732430e-01 | 0.172 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 6.740542e-01 | 0.171 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 6.740542e-01 | 0.171 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 6.759396e-01 | 0.170 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 6.770772e-01 | 0.169 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 6.805809e-01 | 0.167 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 6.805809e-01 | 0.167 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 6.805809e-01 | 0.167 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 6.805809e-01 | 0.167 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.836965e-01 | 0.165 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 6.838767e-01 | 0.165 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 6.838767e-01 | 0.165 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 6.905076e-01 | 0.161 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 6.905076e-01 | 0.161 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 6.912041e-01 | 0.160 | 0 | 0 |
| DAG1 core M3 glycosylations | R-HSA-8932505 | 6.912041e-01 | 0.160 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 6.912041e-01 | 0.160 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 6.912041e-01 | 0.160 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 6.912041e-01 | 0.160 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 6.912041e-01 | 0.160 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 6.912041e-01 | 0.160 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 6.912041e-01 | 0.160 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 6.912041e-01 | 0.160 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 6.948101e-01 | 0.158 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 6.981285e-01 | 0.156 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 6.981285e-01 | 0.156 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 6.989738e-01 | 0.156 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.135163e-01 | 0.147 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.160757e-01 | 0.145 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 7.160757e-01 | 0.145 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 7.160757e-01 | 0.145 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 7.160757e-01 | 0.145 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.160757e-01 | 0.145 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 7.160757e-01 | 0.145 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.160757e-01 | 0.145 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 7.160757e-01 | 0.145 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 7.160757e-01 | 0.145 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 7.160757e-01 | 0.145 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 7.164448e-01 | 0.145 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 7.164448e-01 | 0.145 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.164448e-01 | 0.145 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 7.164448e-01 | 0.145 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.164448e-01 | 0.145 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 7.275100e-01 | 0.138 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 7.275100e-01 | 0.138 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 7.275100e-01 | 0.138 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.330710e-01 | 0.135 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 7.330710e-01 | 0.135 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 7.330710e-01 | 0.135 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 7.389455e-01 | 0.131 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 7.389455e-01 | 0.131 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 7.389455e-01 | 0.131 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 7.389455e-01 | 0.131 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 7.389455e-01 | 0.131 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 7.389455e-01 | 0.131 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 7.389455e-01 | 0.131 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.389455e-01 | 0.131 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 7.389455e-01 | 0.131 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.389455e-01 | 0.131 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.389455e-01 | 0.131 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 7.389455e-01 | 0.131 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.389455e-01 | 0.131 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 7.402185e-01 | 0.131 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 7.402185e-01 | 0.131 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 7.409617e-01 | 0.130 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 7.441273e-01 | 0.128 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 7.488600e-01 | 0.126 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 7.488600e-01 | 0.126 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 7.488600e-01 | 0.126 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 7.488600e-01 | 0.126 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 7.488600e-01 | 0.126 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 7.488600e-01 | 0.126 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 7.488600e-01 | 0.126 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 7.528142e-01 | 0.123 | 0 | 0 |
| Microbial factors inhibit CASP4 activity | R-HSA-9956593 | 7.599743e-01 | 0.119 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 7.638387e-01 | 0.117 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 7.640667e-01 | 0.117 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 7.640667e-01 | 0.117 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 7.640667e-01 | 0.117 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 7.662744e-01 | 0.116 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 7.679223e-01 | 0.115 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 7.682628e-01 | 0.114 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 7.780353e-01 | 0.109 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 7.780353e-01 | 0.109 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 7.780353e-01 | 0.109 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 7.780353e-01 | 0.109 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 7.781556e-01 | 0.109 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 7.781556e-01 | 0.109 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 7.793104e-01 | 0.108 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 7.793104e-01 | 0.108 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 7.793104e-01 | 0.108 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 7.793104e-01 | 0.108 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 7.793104e-01 | 0.108 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 7.793104e-01 | 0.108 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 7.793104e-01 | 0.108 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 7.793104e-01 | 0.108 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 7.793104e-01 | 0.108 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 7.793104e-01 | 0.108 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 7.793104e-01 | 0.108 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 7.793104e-01 | 0.108 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 7.836279e-01 | 0.106 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.867085e-01 | 0.104 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 7.895351e-01 | 0.103 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 7.970898e-01 | 0.098 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 7.970898e-01 | 0.098 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 7.970898e-01 | 0.098 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 7.970898e-01 | 0.098 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 7.970898e-01 | 0.098 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 7.970898e-01 | 0.098 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 7.970898e-01 | 0.098 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 7.970898e-01 | 0.098 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 7.970898e-01 | 0.098 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 7.970898e-01 | 0.098 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 8.004251e-01 | 0.097 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 8.004251e-01 | 0.097 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 8.030643e-01 | 0.095 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 8.041973e-01 | 0.095 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 8.041973e-01 | 0.095 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 8.070198e-01 | 0.093 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 8.108385e-01 | 0.091 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 8.122383e-01 | 0.090 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.134379e-01 | 0.090 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.134379e-01 | 0.090 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.134379e-01 | 0.090 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 8.134379e-01 | 0.090 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 8.134379e-01 | 0.090 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 8.134379e-01 | 0.090 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 8.134379e-01 | 0.090 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 8.134379e-01 | 0.090 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.134379e-01 | 0.090 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 8.134379e-01 | 0.090 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.162214e-01 | 0.088 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 8.207885e-01 | 0.086 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 8.284697e-01 | 0.082 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 8.284697e-01 | 0.082 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.284697e-01 | 0.082 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.284697e-01 | 0.082 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 8.284697e-01 | 0.082 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 8.284697e-01 | 0.082 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 8.284697e-01 | 0.082 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.284697e-01 | 0.082 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 8.289459e-01 | 0.081 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.295358e-01 | 0.081 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 8.302889e-01 | 0.081 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 8.376754e-01 | 0.077 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 8.383025e-01 | 0.077 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 8.383025e-01 | 0.077 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 8.393647e-01 | 0.076 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.422912e-01 | 0.075 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.422912e-01 | 0.075 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 8.422912e-01 | 0.075 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.422912e-01 | 0.075 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.422912e-01 | 0.075 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 8.422912e-01 | 0.075 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.484174e-01 | 0.071 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 8.484174e-01 | 0.071 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 8.484174e-01 | 0.071 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 8.484174e-01 | 0.071 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 8.549997e-01 | 0.068 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 8.549997e-01 | 0.068 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 8.549997e-01 | 0.068 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 8.549997e-01 | 0.068 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.549997e-01 | 0.068 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 8.564226e-01 | 0.067 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 8.566623e-01 | 0.067 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 8.579529e-01 | 0.067 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 8.662142e-01 | 0.062 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 8.666849e-01 | 0.062 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 8.666849e-01 | 0.062 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 8.666849e-01 | 0.062 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 8.666849e-01 | 0.062 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.666849e-01 | 0.062 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 8.666849e-01 | 0.062 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 8.667586e-01 | 0.062 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 8.669368e-01 | 0.062 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 8.674082e-01 | 0.062 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 8.736262e-01 | 0.059 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 8.750013e-01 | 0.058 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 8.753961e-01 | 0.058 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 8.753961e-01 | 0.058 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 8.774290e-01 | 0.057 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 8.774290e-01 | 0.057 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.774290e-01 | 0.057 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 8.774290e-01 | 0.057 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 8.853844e-01 | 0.053 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 8.853844e-01 | 0.053 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 8.873079e-01 | 0.052 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 8.873079e-01 | 0.052 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 8.873079e-01 | 0.052 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 8.873079e-01 | 0.052 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 8.873079e-01 | 0.052 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 8.891795e-01 | 0.051 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 8.936244e-01 | 0.049 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 8.963910e-01 | 0.048 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 8.963910e-01 | 0.048 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 8.963910e-01 | 0.048 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 8.963910e-01 | 0.048 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 8.963910e-01 | 0.048 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 8.972254e-01 | 0.047 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 8.993332e-01 | 0.046 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.044975e-01 | 0.044 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.044975e-01 | 0.044 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.047426e-01 | 0.043 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.047426e-01 | 0.043 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 9.047426e-01 | 0.043 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 9.047426e-01 | 0.043 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.060329e-01 | 0.043 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.075014e-01 | 0.042 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.091397e-01 | 0.041 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.112882e-01 | 0.040 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 9.113506e-01 | 0.040 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 9.122893e-01 | 0.040 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.124214e-01 | 0.040 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.124214e-01 | 0.040 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 9.124214e-01 | 0.040 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.124214e-01 | 0.040 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.124214e-01 | 0.040 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 9.124214e-01 | 0.040 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.143355e-01 | 0.039 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.146637e-01 | 0.039 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 9.165409e-01 | 0.038 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 9.165409e-01 | 0.038 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 9.165409e-01 | 0.038 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.165409e-01 | 0.038 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.165409e-01 | 0.038 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.165409e-01 | 0.038 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.176688e-01 | 0.037 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.176688e-01 | 0.037 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.192593e-01 | 0.037 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.194816e-01 | 0.036 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.194816e-01 | 0.036 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 9.194816e-01 | 0.036 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.220130e-01 | 0.035 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.220130e-01 | 0.035 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.239234e-01 | 0.034 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.253539e-01 | 0.034 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.259731e-01 | 0.033 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.259731e-01 | 0.033 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.259731e-01 | 0.033 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.259731e-01 | 0.033 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.259731e-01 | 0.033 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.259731e-01 | 0.033 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 9.259731e-01 | 0.033 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.259731e-01 | 0.033 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 9.271457e-01 | 0.033 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.287637e-01 | 0.032 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 9.293030e-01 | 0.032 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.297450e-01 | 0.032 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.319415e-01 | 0.031 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.319415e-01 | 0.031 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.319415e-01 | 0.031 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.325188e-01 | 0.030 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.364685e-01 | 0.029 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.374291e-01 | 0.028 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 9.374291e-01 | 0.028 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.374291e-01 | 0.028 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.402960e-01 | 0.027 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.406943e-01 | 0.027 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.406943e-01 | 0.027 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.424745e-01 | 0.026 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 9.424745e-01 | 0.026 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.424745e-01 | 0.026 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.432281e-01 | 0.025 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.470845e-01 | 0.024 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.471134e-01 | 0.024 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.471134e-01 | 0.024 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 9.471134e-01 | 0.024 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 9.471134e-01 | 0.024 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 9.483575e-01 | 0.023 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.513784e-01 | 0.022 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.513784e-01 | 0.022 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.513784e-01 | 0.022 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.550704e-01 | 0.020 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.550704e-01 | 0.020 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 9.550704e-01 | 0.020 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.552997e-01 | 0.020 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.586792e-01 | 0.018 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.588851e-01 | 0.018 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.589050e-01 | 0.018 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.589050e-01 | 0.018 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 9.589050e-01 | 0.018 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.603135e-01 | 0.018 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.611806e-01 | 0.017 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.611806e-01 | 0.017 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.622197e-01 | 0.017 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.622197e-01 | 0.017 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.635391e-01 | 0.016 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 9.635391e-01 | 0.016 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.643613e-01 | 0.016 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.652672e-01 | 0.015 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.652672e-01 | 0.015 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.657622e-01 | 0.015 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 9.677297e-01 | 0.014 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.680691e-01 | 0.014 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.683923e-01 | 0.014 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 9.705560e-01 | 0.013 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.706451e-01 | 0.013 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.706451e-01 | 0.013 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.714197e-01 | 0.013 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.720565e-01 | 0.012 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.725764e-01 | 0.012 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 9.725764e-01 | 0.012 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 9.730134e-01 | 0.012 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.730134e-01 | 0.012 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.730475e-01 | 0.012 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.740240e-01 | 0.011 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.745880e-01 | 0.011 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.751907e-01 | 0.011 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.751907e-01 | 0.011 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.751907e-01 | 0.011 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.762232e-01 | 0.010 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 9.766341e-01 | 0.010 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.768226e-01 | 0.010 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.778661e-01 | 0.010 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.787281e-01 | 0.009 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.790330e-01 | 0.009 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 9.793988e-01 | 0.009 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.793988e-01 | 0.009 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.807250e-01 | 0.008 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 9.807250e-01 | 0.008 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.819616e-01 | 0.008 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.821615e-01 | 0.008 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.821615e-01 | 0.008 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.822805e-01 | 0.008 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 9.834044e-01 | 0.007 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 9.834044e-01 | 0.007 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 9.845630e-01 | 0.007 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.850254e-01 | 0.007 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.850894e-01 | 0.007 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.873453e-01 | 0.006 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.873453e-01 | 0.006 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.873453e-01 | 0.006 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.875862e-01 | 0.005 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.883627e-01 | 0.005 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.893432e-01 | 0.005 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.899355e-01 | 0.004 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.900295e-01 | 0.004 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.901694e-01 | 0.004 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.909340e-01 | 0.004 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.909340e-01 | 0.004 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.909478e-01 | 0.004 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.909631e-01 | 0.004 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.916441e-01 | 0.004 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.916928e-01 | 0.004 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.920009e-01 | 0.003 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.923636e-01 | 0.003 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 9.929803e-01 | 0.003 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.937693e-01 | 0.003 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.940468e-01 | 0.003 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.944721e-01 | 0.002 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.967108e-01 | 0.001 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.967108e-01 | 0.001 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.972912e-01 | 0.001 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.977466e-01 | 0.001 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.977759e-01 | 0.001 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.980480e-01 | 0.001 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.981491e-01 | 0.001 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.983239e-01 | 0.001 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.983341e-01 | 0.001 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.984751e-01 | 0.001 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.985840e-01 | 0.001 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.986217e-01 | 0.001 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.986373e-01 | 0.001 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.990210e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.990711e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.992787e-01 | 0.000 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.992787e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.992787e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.994492e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.995633e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.995652e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.995806e-01 | 0.000 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.996654e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.997738e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.997909e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.998105e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.998532e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.998549e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.998770e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.998774e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999293e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999438e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999633e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999677e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999681e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999683e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999701e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999771e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999793e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999842e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999891e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
