TNIK

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A6NMY6 T163 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
O00203 T424 Sugiyama AP3B1 ADTB3A TLLREFQTYVKSQDKQFAAAtIQtIGRCATNILEVTDTCLN
O00203 T427 Sugiyama AP3B1 ADTB3A REFQTYVKSQDKQFAAAtIQtIGRCATNILEVTDTCLNGLV
O00571 T156 Sugiyama DDX3X DBX DDX3 WSKPLPPSERLEQELFsGGNtGINFEKYDDIPVEATGNNCP
O14744 T80 Sugiyama PRMT5 HRMT1L5 IBP72 JBP1 SKB1 KNRPGPQTRSDLLLSGRDWNtLIVGKLSPWIRPDSKVEKIR
O14908 T238 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 FDMISQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPs
O14908 T242 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 SQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPsAFEE
O14950 T160 Sugiyama MYL12B MRLC2 MYLC2B DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
O15067 T591 Sugiyama PFAS KIAA0361 NRDFLTHVSARERCPACFVGtITGDRRIVLVDDRECPVRRN
O15523 T154 Sugiyama DDX3Y DBY WSKPLPPSERLEQELFsGGNtGINFEKYDDIPVEATGSNCP
O43175 S14 Sugiyama PHGDH PGDH3 _______MAFANLRKVLIsDsLDPCCRKILQDGGLQVVEKQ
O43175 T78 Sugiyama PHGDH PGDH3 KVTADVINAAEKLQVVGRAGtGVDNVDLEAAtRKGILVMNT
O43242 T69 Sugiyama PSMD3 GEADGKtAAAAAEHsQRELDtVtLEDIKEHVKQLEKAVSGK
O43242 T71 Sugiyama PSMD3 ADGKtAAAAAEHsQRELDtVtLEDIKEHVKQLEKAVSGKEP
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43423 T101 Sugiyama ANP32CP PP32R1 EKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCEV
O43707 S507 Sugiyama ACTN4 DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43707 T509 Sugiyama ACTN4 HNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAIDQL
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60361 T88 Sugiyama NME2P1 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O60841 S196 Sugiyama EIF5B IF2 KIAA0741 ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN
O75369 T1444 Sugiyama FLNB FLN1L FLN3 TABP TAP VKIAGPGLGsGVRARVLQsFtVDSSKAGLAPLEVRVLGPRG
O75390 T335 Sugiyama CS LQKEVGKDVSDEKLRDYIWNtLNSGRVVPGyGHAVLRKTDP
O75436 T102 Sugiyama VPS26A VPS26 KSNTHEFVNLVKELALPGELtQSRSYDFEFMQVEKPYESYI
O94776 S433 Sugiyama MTA2 MTA1L1 PID ATRGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQt
O94776 Y437 Sugiyama MTA2 MTA1L1 PID tTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFLLQ
O95260 S503 Sugiyama ATE1 GVYKKQQKDPSEEAAVLQYAsLVGQKCSERMLLFRN_____
O95373 T997 Sugiyama IPO7 RANBP7 yQALTHGLNEEQRKQLQDIAtLADQRRAAHESKMIEKHGGY
O95433 T20 Sugiyama AHSA1 C14orf3 HSPC322 _MAKWGEGDPRWIVEERADAtNVNNWHWtERDASNWSTDKL
O95626 T105 Sugiyama ANP32D PP32R2 EKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCEV
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95757 S587 Sugiyama HSPA4L APG1 HSPH3 OSP94 RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM
O95817 Y240 Sugiyama BAG3 BIS AAQPsFHQAQKTHyPAQQGEyQtHQPVyHKIQGDDWEPRPL
P00338 S319 Sugiyama LDHA PIG19 GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______
P00338 S69 Sugiyama LDHA PIG19 ALVDVIEDKLKGEMMDLQHGsLFLRTPKIVSGKDyNVTANs
P00338 T275 Sugiyama LDHA PIG19 SVADLAESIMKNLRRVHPVstMIKGLYGIKDDVFLSVPCIL
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00491 T202 Sugiyama PNP NP GEQRELQEGTYVMVAGPSFEtVAECRVLQKLGADAVGMSTV
P00505 T186 Sugiyama GOT2 KYAT4 tPIFRDAGMQLQGyRYYDPKtCGFDFtGAVEDISKIPEQSV
P00505 T192 Sugiyama GOT2 KYAT4 AGMQLQGyRYYDPKtCGFDFtGAVEDISKIPEQSVLLLHAC
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 T369 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV
P00558 T376 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P00568 T39 Sugiyama AK1 SGKGTQCEKIVQKyGytHLstGDLLRSEVSSGSARGKKLsE
P00568 Y34 Sugiyama AK1 VGGPGSGKGTQCEKIVQKyGytHLstGDLLRSEVSSGSARG
P00966 S92 Sugiyama ASS1 ASS FIWPAIQSSALYEDRYLLGtsLARPCIARKQVEIAQREGAK
P00966 T91 Sugiyama ASS1 ASS EFIWPAIQSSALYEDRYLLGtsLARPCIARKQVEIAQREGA
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02786 S361 Sugiyama TFRC AAEKLFGNMEGDCPSDWKTDstCRMVTSESKNVKLTVSNVL
P04040 S517 Sugiyama CAT LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________
P04040 T434 Sugiyama CAT QQPSALEHSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEE
P04040 T511 Sugiyama CAT SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075 T119 Sugiyama ALDOA ALDA KsKGGVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYK
P04075 T123 Sugiyama ALDOA ALDA GVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGA
P04083 S182 Sugiyama ANXA1 ANX1 LPC1 RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD
P04083 T136 Sugiyama ANXA1 ANX1 LPC1 AQFDADELRAAMKGLGtDEDtLIEILAsRtNKEIRDINRVY
P04083 T145 Sugiyama ANXA1 ANX1 LPC1 AAMKGLGtDEDtLIEILAsRtNKEIRDINRVYREELKRDLA
P04083 T223 Sugiyama ANXA1 ANX1 LPC1 ARALyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKY
P04083 T226 Sugiyama ANXA1 ANX1 LPC1 LyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKYSKH
P04083 Y230 Sugiyama ANXA1 ANX1 LPC1 GERRKGtDVNVFNtILttRSyPQLRRVFQKYTKYSKHDMNK
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S151 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV
P04406 S321 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406 T153 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 MGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEG
P04406 T154 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEGL
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05362 T436 Sugiyama ICAM1 TPMCQAWGNPLPELKCLKDGtFPLPIGEsVtVtRDLEGtyL
P05362 T446 Sugiyama ICAM1 LPELKCLKDGtFPLPIGEsVtVtRDLEGtyLCRARSTQGEV
P05388 T122 Sugiyama RPLP0 LLANKVPAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALG
P05388 T128 Sugiyama RPLP0 PAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALGItTKIS
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05455 T123 Sugiyama SSB EyKNDVKNRsVYIKGFPtDAtLDDIKEWLEDKGQVLNIQMR
P05783 T404 Sugiyama KRT18 CYK18 PIG46 LEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVVsETND
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S258 Sugiyama KRT8 CYK8 QISDTSVVLsMDNSRsLDMDsIIAEVKAQyEDIANRsRAEA
P06576 T334 Sugiyama ATP5F1B ATP5B ATPMB ATPSB AGsEVsALLGRIPSAVGYQPtLATDMGtMQERITTTKKGSI
P06576 T341 Sugiyama ATP5F1B ATP5B ATPMB ATPSB LLGRIPSAVGYQPtLATDMGtMQERITTTKKGSITSVQAIY
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T18 Sugiyama LDHB ___MATLKEKLIAPVAEEEAtVPNNKITVVGVGQVGMACAI
P07195 T276 Sugiyama LDHB SVADLIESMLKNLSRIHPVStMVKGMYGIENEVFLSLPCIL
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 T117 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB RGyPtIKFFRNGDTASPKEytAGREADDIVNWLKKRTGPAA
P07339 T334 Sugiyama CTSD CPSD AIGAVPLIQGEYMIPCEKVstLPAItLKLGGKGYKLsPEDY
P07339 T339 Sugiyama CTSD CPSD PLIQGEYMIPCEKVstLPAItLKLGGKGYKLsPEDYTLKVs
P07355 T163 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 T55 Sugiyama TUBB TUBB5 OK/SW-cl.56 tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07737 S133 Sugiyama PFN1 LMGKEGVHGGLINKKCyEMAsHLRRsQY_____________
P07737 S85 Sugiyama PFN1 tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK
P07737 T65 Sugiyama PFN1 PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs
P07814 T1506 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 LCELQPGAKCVCGKNPAKyytLFGRsy______________
P07814 T707 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 VsPysCKEAPCVLIyIPDGHtKEMPTSGSKEKTKVEATKNE
P07900 S63 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P07900 T109 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LtIVDtGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
P07900 T171 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILHLK
P07900 T624 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE
P07900 T645 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL
P07900 T65 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQ
P07900 T88 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA sKLDsGKELHINLIPNKQDRtLtIVDtGIGMTKADLINNLG
P07900 T90 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LDsGKELHINLIPNKQDRtLtIVDtGIGMTKADLINNLGtI
P07900 T94 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KELHINLIPNKQDRtLtIVDtGIGMTKADLINNLGtIAKSG
P08195 T599 Sugiyama SLC3A2 MDU1 QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S58 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238 T104 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LtLVDtGIGMtKADLINNLGtIAKSGtKAFMEALQAGADIS
P08238 T166 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILHLK
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 T60 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQ
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08238 T637 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P08758 T8 Sugiyama ANXA5 ANX5 ENX2 PP4 _____________MAQVLRGtVtDFPGFDERADAEtLRKAM
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09211 T68 Sugiyama GSTP1 FAEES3 GST3 CLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQEAA
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P09923 Y179 Sugiyama ALPI GKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQ
P09960 T507 Sugiyama LTA4H LTA4 FNAtDLKDLsSHQLNEFLAQtLQRAPLPLGHIKRMQEVYNF
P09972 T119 Sugiyama ALDOC ALDC QDKGIVVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYK
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DPH7 T334 Sugiyama TUBA3C TUBA2 ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
P0DPH7 T41 Sugiyama TUBA3C TUBA2 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P0DPH7 T51 Sugiyama TUBA3C TUBA2 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P0DPH7 T56 Sugiyama TUBA3C TUBA2 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10809 S383 Sugiyama HSPD1 HSP60 DKAQIEKRIQEIIEQLDVttsEyEKEKLNERLAKLsDGVAV
P10809 T173 Sugiyama HSPD1 HSP60 AELKKQsKPVttPEEIAQVAtIsANGDKEIGNIIsDAMKKV
P10809 T206 Sugiyama HSPD1 HSP60 IsDAMKKVGRKGVITVKDGKtLNDELEIIEGMKFDRGyIsP
P10809 T231 Sugiyama HSPD1 HSP60 LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P10809 T320 Sugiyama HSPD1 HSP60 VKAPGFGDNRKNQLKDMAIAtGGAVFGEEGLtLNLEDVQPH
P10809 T331 Sugiyama HSPD1 HSP60 NQLKDMAIAtGGAVFGEEGLtLNLEDVQPHDLGKVGEVIVt
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S432 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMTKD
P11142 T158 Sugiyama HSPA8 HSC70 HSP73 HSPA10 tVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T222 Sugiyama HSPA8 HSC70 HSP73 HSPA10 GGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFI
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T313 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FYTSITRARFEELNADLFRGtLDPVEKALRDAKLDKsQIHD
P11142 T425 Sugiyama HSPA8 HSC70 HSP73 HSPA10 TAGGVMTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEG
P11142 T427 Sugiyama HSPA8 HSC70 HSP73 HSPA10 GGVMTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGER
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11586 S129 Sugiyama MTHFD1 MTHFC MTHFD INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P11940 T379 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 AtKPLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINP
P11940 T71 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 sLGyAyVNFQQPADAERALDtMNFDVIKGKPVRIMWSQRDP
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12268 S416 Sugiyama IMPDH2 IMPD2 APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12268 S505 Sugiyama IMPDH2 IMPD2 SGELKFEKRtssAQVEGGVHsLHsyEKRLF___________
P12268 T252 Sugiyama IMPDH2 IMPD2 DYPLASKDAKKQLLCGAAIGtHEDDKYRLDLLAQAGVDVVV
P12268 Y509 Sugiyama IMPDH2 IMPD2 KFEKRtssAQVEGGVHsLHsyEKRLF_______________
P12270 T1039 Sugiyama TPR QDDKRRAIESMEQQLSELKKtLSSVQNEVQEALQRASTALS
P12814 T426 Sugiyama ACTN1 HEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEsDLAA
P12814 T490 Sugiyama ACTN1 PsVNARCQKICDQWDNLGALtQKRREALERTEKLLETIDQL
P12814 Y422 Sugiyama ACTN1 KAsIHEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEs
P13010 T472 Sugiyama XRCC5 G22P2 NAVDALIDSMSLAKKDEKTDtLEDLFPTTKIPNPRFQRLFQ
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 T34 Sugiyama EEF2 EF2 DKKANIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEt
P13639 T484 Sugiyama EEF2 EF2 VPCGNIVGLVGVDQFLVKtGtIttFEHAHNMRVMKFsVsPV
P13639 T486 Sugiyama EEF2 EF2 CGNIVGLVGVDQFLVKtGtIttFEHAHNMRVMKFsVsPVVR
P13639 T5 Sugiyama EEF2 EF2 ________________MVNFtVDQIRAIMDKKANIRNMsVI
P13639 T735 Sugiyama EEF2 EF2 HRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCPEQV
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667 T380 Sugiyama PDIA4 ERP70 ERP72 PEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGHR
P13674 T140 Sugiyama P4HA1 P4HA YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13796 T174 Sugiyama LCP1 PLS2 FNAVGDGIVLCKMINLSVPDtIDERTINKKKLTPFTIQENL
P13797 T177 Sugiyama PLS3 FKAVGDGIVLCKMINLSVPDtIDERAINKKKLTPFIIQENL
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P14314 T115 Sugiyama PRKCSH G19P1 GVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQQMAEVtR
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14314 T489 Sugiyama PRKCSH G19P1 tGCWQGPNRstTVRLLCGKEtMVtStTEPSRCEYLMELMTP
P14314 T492 Sugiyama PRKCSH G19P1 WQGPNRstTVRLLCGKEtMVtStTEPSRCEYLMELMTPAAC
P14314 T494 Sugiyama PRKCSH G19P1 GPNRstTVRLLCGKEtMVtStTEPSRCEYLMELMTPAACPE
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625 S64 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14649 T101 Sugiyama MYL6B MLC1SA DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDELKSRR
P15259 T96 Sugiyama PGAM2 PGAMM QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQVKIWR
P15311 T299 Sugiyama EZR VIL2 RILQLCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQLE
P15531 T103 Sugiyama NME1 NDPKA NM23 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P15880 T202 Sugiyama RPS2 RPS4 CKVTGRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDC
P15880 T224 Sugiyama RPS2 RPS4 IVsAPVPKKLLMMAGIDDCytsARGCtAtLGNFAKATFDAI
P15880 T230 Sugiyama RPS2 RPS4 PKKLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysy
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P16083 T59 Sugiyama NQO2 NMOR2 VSDLyAMNLEPRATDKDITGtLSNPEVFNyGVEtHEAyKQR
P16083 T72 Sugiyama NQO2 NMOR2 TDKDITGtLSNPEVFNyGVEtHEAyKQRsLAsDITDEQKKV
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17174 S106 Sugiyama GOT1 RLALGDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNG
P17174 T110 Sugiyama GOT1 GDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNGTNNK
P18621 S111 Sugiyama RPL17 LLHMLKNAESNAELKGLDVDsLVIEHIQVNKAPKMRRRTYR
P18621 S142 Sugiyama RPL17 APKMRRRTYRAHGRINPyMssPCHIEMILtEKEQIVPKPEE
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18621 T12 Sugiyama RPL17 _________MVRysLDPENPtKsCKSRGSNLRVHFKNtRET
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T146 Sugiyama PGAM1 PGAMA CDABP0006 MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P18669 T96 Sugiyama PGAM1 PGAMA CDABP0006 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
P19105 T159 Sugiyama MYL12A MLCB MRLC3 RLC DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S595 Sugiyama NCL FVKGLsEDttEEtLKEsFDGsVRARIVTDRETGssKGFGFV
P19338 T464 Sugiyama NCL KTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsGE
P19338 T587 Sugiyama NCL RSQPSKTLFVKGLsEDttEEtLKEsFDGsVRARIVTDRETG
P19338 Y463 Sugiyama NCL EKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsG
P20073 T203 Sugiyama ANXA7 ANX7 SNX OK/SW-cl.95 ANFDAIRDAEILRKAMKGFGtDEQAIVDVVANRsNDQRQKI
P20618 S151 Sugiyama PSMB1 PSC5 PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20618 S162 Sugiyama PSMB1 PSC5 DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG
P22090 S204 Sugiyama RPS4Y1 RPS4Y PRO2646 IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22234 S223 Sugiyama PAICS ADE2 AIRC PAIS IVLADVIDNDsWRLWPSGDRsQQKDKQSYRDLKEVtPEGLQ
P22314 T668 Sugiyama UBA1 A1S9T UBE1 ARDEFEGLFKQPAENVNQyLtDPKFVERtLRLAGtQPLEVL
P22314 T682 Sugiyama UBA1 A1S9T UBE1 NVNQyLtDPKFVERtLRLAGtQPLEVLEAVQRSLVLQRPQT
P22392 T103 Sugiyama NME2 NM23B VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P22626 S201 Sugiyama HNRNPA2B1 HNRPA2B1 NAEVRKALsRQEMQEVQssRsGRGGNFGFGDsRGGGGNFGP
P22626 T140 Sugiyama HNRNPA2B1 HNRPA2B1 KEDTEEHHLRDyFEEYGKIDtIEIItDRQsGKKRGFGFVtF
P23381 S378 Sugiyama WARS1 IFI53 WARS WRS sIFLtDtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDV
P23381 T383 Sugiyama WARS1 IFI53 WARS WRS DtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDVSFMYL
P23396 T242 Sugiyama RPS3 OK/SW-cl.26 PIsEQKGGKPEPPAMPQPVPtA___________________
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23921 T120 Sugiyama RRM1 RR1 DLyNyINPHNGKHSPMVAKstLDIVLANKDRLNsAIIYDRD
P23921 T555 Sugiyama RRM1 RR1 IyyGALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTP
P24752 T220 Sugiyama ACAT1 ACAT MAT TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV
P25705 S198 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK
P25705 T225 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM GQRELIIGDRQTGKTSIAIDtIINQKRFNDGsDEKKKLyCI
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26038 T299 Sugiyama MSN RILALCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQME
P26038 T526 Sugiyama MSN EERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHA
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26373 T24 Sugiyama RPL13 BBC1 OK/SW-cl.46 SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR
P26447 T15 Sugiyama S100A4 CAPL MTS1 ______MACPLEKALDVMVstFHKYSGKEGDKFKLNKSELK
P26639 T700 Sugiyama TARS1 TARS EKISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAE
P26639 T704 Sugiyama TARS1 TARS GTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEEF_
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P26641 T411 Sugiyama EEF1G EF1G PRO1608 QVDyESyTWRKLDPGsEEtQtLVREyFSWEGAFQHVGKAFN
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27797 T173 Sugiyama CALR CRTC KNVLINKDIRCKDDEFTHLytLIVRPDNtyEVKIDNsQVEs
P27797 T181 Sugiyama CALR CRTC IRCKDDEFTHLytLIVRPDNtyEVKIDNsQVEsGsLEDDWD
P28066 T161 Sugiyama PSMA5 LLFGGVDEKGPQLFHMDPsGtFVQCDARAIGsAsEGAQssL
P29401 S124 Sugiyama TKT ssDLDGHPVPKQAFtDVATGsLGQGLGAACGMAYTGKYFDK
P29401 T118 Sugiyama TKT LNLRKIssDLDGHPVPKQAFtDVATGsLGQGLGAACGMAYT
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29401 T454 Sugiyama TKT LAMFRsVPtstVFyPsDGVAtEKAVELAANTKGICFIRTsR
P30048 S86 Sugiyama PRDX3 AOP1 TQHAPYFKGTAVVNGEFKDLsLDDFKGKYLVLFFYPLDFTF
P30050 T25 Sugiyama RPL12 FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD
P30086 S109 Sugiyama PEBP1 PBP PEBP VVNMKGNDIssGtVLsDyVGsGPPKGtGLHRyVWLVyEQDR
P30086 S98 Sugiyama PEBP1 PBP PEBP DPKYREWHHFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLH
P30086 T115 Sugiyama PEBP1 PBP PEBP NDIssGtVLsDyVGsGPPKGtGLHRyVWLVyEQDRPLKCDE
P30101 S478 Sugiyama PDIA3 ERP57 ERP60 GRP58 ANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKK
P30419 T122 Sugiyama NMT1 NMT GQGPAKTMEEASKRSyQFWDtQPVPKLGEVVNtHGPVEPDK
P30740 S72 Sugiyama SERPINB1 ELANH2 MNEI PI2 AQLSKTFHFNTVEEVHSRFQsLNADINKRGASYILKLANRL
P31153 T240 Sugiyama MAT2A AMS2 MATA2 DALKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAG
P31153 T262 Sugiyama MAT2A AMS2 MATA2 yHLQPsGRFVIGGPQGDAGLtGRKIIVDTYGGWGAHGGGAF
P31327 T206 Sugiyama CPS1 EGQPVDFVDPNKQNLIAEVstKDVKVYGKGNPTKVVAVDCG
P31943 T282 Sugiyama HNRNPH1 HNRPH HNRPH1 RDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtE
P31943 T287 Sugiyama HNRNPH1 HNRPH HNRPH1 CFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIyN
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P33176 T809 Sugiyama KIF5B KNS KNS1 VAKELQTLHNLRKLFVQDLAtRVKKSAEIDsDDTGGsAAQK
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34932 T758 Sugiyama HSPA4 APG2 HSPH2 TNEAMEWMNNKLNLQNKQsLtMDPVVKSKEIEAKIKELTst
P35241 T299 Sugiyama RDX RILALCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQLE
P35268 T62 Sugiyama RPL22 FLQERIKVNGKAGNLGGGVVtIERsKSKITVTSEVPFSKRY
P35579 T1208 Sugiyama MYH9 QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE
P35579 T1764 Sugiyama MYH9 NtELINDRLKKANLQIDQINtDLNLERSHAQKNENARQQLE
P35579 T309 Sugiyama MYH9 KTDLLLEPyNKyRFLsNGHVtIPGQQDKDMFQETMEAMRIM
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36578 S63 Sugiyama RPL4 RPL1 NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG
P36578 S66 Sugiyama RPL4 RPL1 KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T23 Sugiyama RPL4 RPL1 CARPLISVysEKGESSGKNVtLPAVFKAPIRPDIVNFVHTN
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578 T69 Sugiyama RPL4 RPL1 RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P37108 S84 Sugiyama SRP14 KKKISTVVSSKEVNKFQMAysNLLRANMDGLKKRDKKNKTK
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P39023 T189 Sugiyama RPL3 OK/SW-cl.32 RLLPLRQKKAHLMEIQVNGGtVAEKLDWARERLEQQVPVNQ
P39687 T105 Sugiyama ANP32A C15orf1 LANP MAPM PHAP1 EKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCEV
P40261 S213 Sugiyama NNMT LVIMDALKSSYYMIGEQKFSsLPLGREAVEAAVKEAGYTIE
P40763 T389 Sugiyama STAT3 APRF DKDSGDVAALRGSRKFNILGtNTKVMNMEESNNGSLSAEFK
P40925 S141 Sugiyama MDH1 MDHA KKSVKVIVVGNPANtNCLtAsKSAPSIPKENFsCLtRLDHN
P40925 T139 Sugiyama MDH1 MDHA YAKKSVKVIVVGNPANtNCLtAsKSAPSIPKENFsCLtRLD
P40925 T225 Sugiyama MDH1 MDHA KEVGVyEALKDDsWLKGEFVttVQQRGAAVIKARKLssAMS
P40926 T224 Sugiyama MDH2 TIIPLISQCtPKVDFPQDQLtALtGRIQEAGtEVVKAKAGA
P40926 T227 Sugiyama MDH2 PLISQCtPKVDFPQDQLtALtGRIQEAGtEVVKAKAGAGsA
P41091 T41 Sugiyama EIF2S3 EIF2G ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
P41091 T46 Sugiyama EIF2S3 EIF2G tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHt
P41223 T115 Sugiyama BUD31 EDG2 QGYENLCCLRCIQTRDtNFGtNCICRVPKSKLEVGRIIECT
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42858 S13 PSP HTT HD IT15 ________MAtLEKLMKAFEsLKsFQQQQQQQQQQQQQQQQ
P42858 T3 PSP HTT HD IT15 __________________MAtLEKLMKAFEsLKsFQQQQQQ
P43034 T139 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA VFSVMVSASEDATIKVWDyEtGDFERtLKGHtDsVQDIsFD
P43034 T145 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA SASEDATIKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLL
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46776 T95 Sugiyama RPL27A LDKLWtLVsEQtRVNAAKNKtGAAPIIDVVRsGyyKVLGKG
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 T177 Sugiyama RPL5 MSTP030 NKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRK
P46779 T80 Sugiyama RPL28 VVVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKN
P46779 T81 Sugiyama RPL28 VVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKNK
P46782 S75 Sugiyama RPS5 RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH
P46782 T73 Sugiyama RPS5 AGRYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIV
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P46783 T93 Sugiyama RPS10 NEGIQYLRDyLHLPPEIVPAtLRRSRPETGRPRPKGLEGER
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P47897 T518 Sugiyama QARS1 QARS KILQLVATGAVRDWDDPRLFtLtALRRRGFPPEAINNFCAR
P47897 T520 Sugiyama QARS1 QARS LQLVATGAVRDWDDPRLFtLtALRRRGFPPEAINNFCARVG
P47914 T155 Sugiyama RPL29 AQAAAPAsVPAQAPKRtQAPtKAsE________________
P48643 T47 Sugiyama CCT5 CCTE KIAA0098 RLMGLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGD
P48643 T50 Sugiyama CCT5 CCTE KIAA0098 GLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtV
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P49327 T1999 Sugiyama FASN FAS LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF
P49327 T2230 Sugiyama FASN FAS LAQQQtQLNLRSLLVNPEGPtLMRLNsVQssERPLFLVHPI
P49327 T295 Sugiyama FASN FAS SLyQsAGVAPEsFEyIEAHGtGTKVGDPQELNGItRALCAt
P49368 T430 Sugiyama CCT3 CCTG TRIC5 GGGASEMAVAHALTEKSKAMtGVEQWPyRAVAQALEVIPRT
P49368 T459 Sugiyama CCT3 CCTG TRIC5 AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG
P49736 T857 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 KQLVAEQVTyQRNRFGAQQDtIEVPEKDLVDKARQINIHNL
P49773 T17 Sugiyama HINT1 HINT PKCI1 PRKCNH1 ____MADEIAKAQVARPGGDtIFGKIIRKEIPAKIIFEDDR
P49902 S418 Sugiyama NT5C2 NT5B NT5CP PNT5 FLAELYKHLDssSNERPDIssIQRRIKKVTHDMDMCYGMMG
P50395 T205 Sugiyama GDI2 RABGDIB TGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsPYL
P50914 T43 Sugiyama RPL14 KLVAIVDVIDQNRALVDGPCtQVRRQAMPFKCMQLTDFILK
P50990 S161 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EILPNLVCCsAKNLRDIDEVssLLRTSIMSKQyGNEVFLAK
P50990 S162 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 ILPNLVCCsAKNLRDIDEVssLLRTSIMSKQyGNEVFLAKL
P50990 T374 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDD
P50991 T69 Sugiyama CCT4 CCTD SRB RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR
P50991 T76 Sugiyama CCT4 CCTD SRB GMDKMIQDGKGDVtItNDGAtILKQMQVLHPAARMLVELSK
P51153 S164 Sugiyama RAB13 GIG4 GIRFFETSAKSsMNVDEAFSsLARDILLKSGGRRsGNGNKP
P51858 T94 Sugiyama HDGF HMG1L2 GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP
P52272 S633 Sugiyama HNRNPM HNRPM NAGR1 GGGGAsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKAC
P52272 S637 Sugiyama HNRNPM HNRPM NAGR1 AsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKACQIFV
P53621 T821 Sugiyama COPA IMPLDTNWPLLTVSKGFFEGtIAsKGKGGALAADIDIDTVG
P54652 T225 Sugiyama HSPA2 GGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLA
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P55010 T227 Sugiyama EIF5 ttEEAQRRRMDEISDHAKVLtLsDDLERtIEERVNILFDFV
P55010 T235 Sugiyama EIF5 RMDEISDHAKVLtLsDDLERtIEERVNILFDFVKKKKEEGV
P55036 S358 Sugiyama PSMD4 MCB1 VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55209 T64 Sugiyama NAP1L1 NRP QNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNL
P56192 S127 Sugiyama MARS1 MARS GKKGEDVLGSVRRALTHIDHsLSRQNCPFLAGETESLADIV
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T38 Sugiyama TPI1 TPI RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 T44 Sugiyama MYL6 DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDEMNVKV
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T202 Sugiyama ACTB GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709 T203 Sugiyama ACTB RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P60709 T229 Sugiyama ACTB VRDIKEKLCyVALDFEQEMAtAAssssLEKsyELPDGQVIt
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T297 Sugiyama ACTB TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709 T303 Sugiyama ACTB MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P60709 T304 Sugiyama ACTB KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60842 T80 Sugiyama EIF4A1 DDX2A EIF4A QRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDLKA
P61160 T15 Sugiyama ACTR2 ARP2 ______MDSQGRKVVVCDNGtGFVKCGYAGSNFPEHIFPAL
P61163 T248 Sugiyama ACTR1A CTRN1 PQKDETLETEKAQyyLPDGstIEIGPSRFRAPELLFRPDLI
P61247 S203 Sugiyama RPS3A FTE1 MFTL EVVNKLIPDsIGKDIEKACQsIyPLHDVFVRKVKMLKKPKF
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61313 T80 Sugiyama RPL15 EC45 TCBAP0781 VIyRIRVRRGGRKRPVPKGAtyGKPVHHGVNQLKFARsLQs
P61513 S21 Sugiyama RPL37A MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQHAKYTCSF
P61513 Y14 Sugiyama RPL37A _______MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQH
P61769 T106 Sugiyama B2M CDABP0092 HDCMA22P YYTEFTPTEKDEYACRVNHVtLsQPKIVKWDRDM_______
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981 T210 Sugiyama YWHAG PEQACHLAKtAFDDAIAELDtLNEDsyKDstLIMQLLRDNL
P62191 T292 Sugiyama PSMC1 RVAEEHAPSIVFIDEIDAIGtKRYDSNSGGEREIQRTMLEL
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62258 T229 Sugiyama YWHAE LsEEsyKDstLIMQLLRDNLtLWtsDMQGDGEEQNKEALQD
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62263 T140 Sugiyama RPS14 PRO2640 ARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL_________
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62266 T34 Sugiyama RPS23 RSHRRDQKWHDKQYKKAHLGtALKANPFGGAsHAKGIVLEK
P62273 S9 Sugiyama RPS29 ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T28 Sugiyama RPS11 RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62312 T75 Sugiyama LSM6 QLKNKyGDAFIRGNNVLyIstQKRRM_______________
P62314 T57 Sugiyama SNRPD1 NTHLKAVKMTLKNREPVQLEtLsIRGNNIRYFILPDsLPLD
P62333 T104 Sugiyama PSMC6 SUG2 RRQLDKSKLKPGTRVALDMTtLtIMRYLPREVDPLVYNMsH
P62333 T106 Sugiyama PSMC6 SUG2 QLDKSKLKPGTRVALDMTtLtIMRYLPREVDPLVYNMsHED
P62424 T142 Sugiyama RPL7A SURF-3 SURF3 AAGKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVD
P62424 T144 Sugiyama RPL7A SURF-3 SURF3 GKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVDPI
P62424 T145 Sugiyama RPL7A SURF-3 SURF3 KGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVDPIE
P62701 S204 Sugiyama RPS4X CCG2 RPS4 SCAR tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62826 T21 Sugiyama RAN ARA24 OK/SW-cl.81 MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62826 T24 Sugiyama RAN ARA24 OK/SW-cl.81 QGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVATLG
P62826 T25 Sugiyama RAN ARA24 OK/SW-cl.81 GEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGV
P62826 T32 Sugiyama RAN ARA24 OK/SW-cl.81 KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62851 T113 Sugiyama RPS25 sKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA________
P62851 Y109 Sugiyama RPS25 QELLsKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA____
P62857 S39 Sugiyama RPS28 GRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLL
P62857 S41 Sugiyama RPS28 tGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLLEs
P62857 T57 Sugiyama RPS28 DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62913 T44 Sugiyama RPL11 ICVGEsGDRLtRAAKVLEQLtGQtPVFsKARyTVRsFGIRR
P62913 T47 Sugiyama RPL11 GEsGDRLtRAAKVLEQLtGQtPVFsKARyTVRsFGIRRNEK
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 T143 Sugiyama RPL8 RGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANR
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62942 T15 Sugiyama FKBP1A FKBP1 FKBP12 ______MGVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGK
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 T147 Sugiyama RPS27A UBA80 UBCEP1 GAGVFMAsHFDRHyCGKCCLtyCFNKPEDK___________
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63104 T226 Sugiyama YWHAZ LsEEsyKDstLIMQLLRDNLtLWtsDtQGDEAEAGEGGEN_
P63151 S412 Sugiyama PPP2R2A LKPRKVCASGKRKKDEIsVDsLDFNKKILHTAWHPKENIIA
P63167 T26 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T202 Sugiyama ACTG1 ACTG GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261 T203 Sugiyama ACTG1 ACTG RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P63261 T229 Sugiyama ACTG1 ACTG VRDIKEKLCyVALDFEQEMAtAAssssLEKsyELPDGQVIt
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T297 Sugiyama ACTG1 ACTG TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261 T303 Sugiyama ACTG1 ACTG MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P63261 T304 Sugiyama ACTG1 ACTG KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P67809 S209 Sugiyama YBX1 NSEP1 YB1 RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 T126 Sugiyama YBX1 NSEP1 YB1 GEtVEFDVVEGEKGAEAANVtGPGGVPVQGsKYAADRNHYR
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P67936 T237 Sugiyama TPM4 IDDLEEKLAQAKEENVGLHQtLDQtLNELNCI_________
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T261 Sugiyama EEF1A1 EEF1A EF1A LENG7 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 T334 Sugiyama TUBA1B ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG
P68363 T41 Sugiyama TUBA1B WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P68363 T51 Sugiyama TUBA1B QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P68363 T56 Sugiyama TUBA1B MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371 T474 Sugiyama CCT2 99D8.1 CCTB AGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGIT
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P84098 S122 Sugiyama RPL19 LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q00796 T75 Sugiyama SORD GRIGNFIVKKPMVLGHEAsGtVEKVGSSVKHLKPGDRVAIE
Q00839 S59 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 QAALDDEEAGGRPAMEPGNGsLDLGGDsAGRSGAGLEQEAA
Q00839 T530 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KTTWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtG
Q00839 T532 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 TWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtGKL
Q00839 T582 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 CLGKFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRK
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q01518 T165 Sugiyama CAP1 CAP AMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVKA
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q02543 T101 Sugiyama RPL18A WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02543 T168 Sugiyama RPL18A SKIKFPLPHRVLRRQHKPRFttKRPNtFF____________
Q02543 T169 Sugiyama RPL18A KIKFPLPHRVLRRQHKPRFttKRPNtFF_____________
Q02543 T24 Sugiyama RPL18A SGTLREYKVVGRCLPTPKCHtPPLYRMRIFAPNHVVAKSRF
Q02543 Y97 Sugiyama RPL18A NFGIWLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARH
Q02878 T118 Sugiyama RPL6 TXREB1 GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR
Q02878 T213 Sugiyama RPL6 TXREB1 FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q02878 T91 Sugiyama RPL6 TXREB1 RKYSAAKSKVEKKKKEKVLAtVtKPVGGDKNGGTRVVKLRK
Q04760 T35 Sugiyama GLO1 AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T261 Sugiyama EEF1A2 EEF1AL STN PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q07157 T1167 Sugiyama TJP1 ZO1 EQAPRAsALRHEEQPAPGyDtHGRLRPEAQPHPsAGPKPAE
Q08J23 S322 Sugiyama NSUN2 SAKI TRM4 IATRGAEQLAEGGRMVYSTCsLNPIEDEAVIASLLEKSEGA
Q12931 T641 Sugiyama TRAP1 HSP75 HSPC5 FLRMQQLAKTQEERAQLLQPtLEINPRHALIKKLNQLRASE
Q13283 S250 Sugiyama G3BP1 G3BP sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI
Q13283 S253 Sugiyama G3BP1 G3BP PAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPH
Q13283 T21 Sugiyama G3BP1 G3BP MVMEKPsPLLVGREFVRQyytLLNQAPDMLHRFYGKNssyV
Q13283 T248 Sugiyama G3BP1 G3BP QKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVT
Q13310 T71 Sugiyama PABPC4 APP1 PABP4 sLGyAyVNFQQPADAERALDtMNFDVIKGKPIRIMWSQRDP
Q13347 T201 Sugiyama EIF3I EIF3S2 TRIP1 LVNVKEHSRQINDIQLsRDMtMFVtASKDNTAKLFDsttLE
Q13347 T205 Sugiyama EIF3I EIF3S2 TRIP1 KEHSRQINDIQLsRDMtMFVtASKDNTAKLFDsttLEHQKT
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13509 T312 Sugiyama TUBB3 TUBB4 QMFDAKNMMAACDPRHGRYLtVAtVFRGRMSMKEVDEQMLA
Q13509 T315 Sugiyama TUBB3 TUBB4 DAKNMMAACDPRHGRYLtVAtVFRGRMSMKEVDEQMLAIQS
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13765 T214 Sugiyama NACA HSD48 KAVRALKNNSNDIVNAIMELtM___________________
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q14103 T91 Sugiyama HNRNPD AUF1 HNRPD sKNEEDEGHsNssPRHsEAAtAQREEWKMFIGGLSWDTTKK
Q14152 S1188 Sugiyama EIF3A EIF3S10 KIAA0139 PWRPLVKPGGWREKEKAREEsWGPPRESRPsEEREWDREKE
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14240 T81 Sugiyama EIF4A2 DDX2B EIF4F QRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEFKE
Q14568 T109 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LTIVDTGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
Q14568 T171 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 ITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILHLK
Q14683 T638 Sugiyama SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 VCDNVEDARRIAFGGHQRHKtVALDGtLFQKsGVISGGASD
Q14683 T644 Sugiyama SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 DARRIAFGGHQRHKtVALDGtLFQKsGVISGGASDLKAKAR
Q14914 T83 Sugiyama PTGR1 LTB4DH MMGQQVAKVVESKNVALPKGtIVLAsPGWttHSISDGKDLE
Q14914 T92 Sugiyama PTGR1 LTB4DH VESKNVALPKGtIVLAsPGWttHSISDGKDLEKLLTEWPDT
Q14974 S201 Sugiyama KPNB1 NTF97 MRKEEPSNNVKLAAtNALLNsLEFTKANFDKESERHFIMQV
Q14974 T195 Sugiyama KPNB1 NTF97 TAIIQGMRKEEPSNNVKLAAtNALLNsLEFTKANFDKESER
Q14974 T860 Sugiyama KPNB1 NTF97 RPMIHELLTEGRRSKTNKAKtLAtWATKELRKLKNQA____
Q14974 T863 Sugiyama KPNB1 NTF97 IHELLTEGRRSKTNKAKtLAtWATKELRKLKNQA_______
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15075 T235 Sugiyama EEA1 ZFYVE2 LQRPGIEDVAVLKKELVQVQtLMDNMtLERERESEKLKDEC
Q15075 T241 Sugiyama EEA1 ZFYVE2 EDVAVLKKELVQVQtLMDNMtLERERESEKLKDECKKLQSQ
Q15084 T100 Sugiyama PDIA6 ERP5 P5 TXNDC7 AVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPEDYQGGRTG
Q15084 Y93 Sugiyama PDIA6 ERP5 P5 TXNDC7 KDVVKVGAVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPED
Q15181 T245 Sugiyama PPA1 IOPPP PP DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA
Q15181 T246 Sugiyama PPA1 IOPPP PP HWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDAL
Q15293 S69 Sugiyama RCN1 RCN PPEDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVD
Q15293 T144 Sugiyama RCN1 RCN WKDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtF
Q15293 T163 Sugiyama RCN1 RCN AtyGyyLGNPAEFHDssDHHtFKKMLPRDERRFKAADLNGD
Q15293 T211 Sugiyama RCN1 RCN FTAFLHPEEFEHMKEIVVLEtLEDIDKNGDGFVDQDEyIAD
Q15365 S111 Sugiyama PCBP1 TAASRPPVTLRLVVPATQCGsLIGKGGCKIKEIREstGAQV
Q15393 S1184 Sugiyama SF3B3 KIAA0017 SAP130 RSyyFPVKNVIDGDLCEQFNsMEPNKQKNVSEELDRtPPEV
Q15459 S508 Sugiyama SF3A1 SAP114 IGEEEIQKPEEKVTWDGHsGsMARTQQAAQANITLQEQIEA
Q15691 S140 Sugiyama MAPRE1 DGKDyDPVAARQGQEtAVAPsLVAPALNKPKKPLtsssAAP
Q15691 T135 Sugiyama MAPRE1 FDANyDGKDyDPVAARQGQEtAVAPsLVAPALNKPKKPLts
Q15797 T322 GPS6|SIGNOR|EPSD|PSP SMAD1 BSP1 MADH1 MADR1 PSNNKNRFCLGLLsNVNRNstIENTRRHIGKGVHLYYVGGE
Q16643 T161 Sugiyama DBN1 D0S117E ssPVLHRLRLREDENAEPVGttyQKTDAAVEMKRINREQFW
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q16775 T292 Sugiyama HAGH GLO2 HAGH1 FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____
Q2VIR3 T41 Sugiyama EIF2S3B ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
Q2VIR3 T46 Sugiyama EIF2S3B tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHT
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3ZCM7 T72 Sugiyama TUBB8 NEASGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIF
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q58FF6 S34 Sugiyama HSP90AB4P IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN
Q58FF6 T36 Sugiyama HSP90AB4P LQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPNPR
Q58FF7 S58 Sugiyama HSP90AB3P HSP90BC IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q58FF7 T60 Sugiyama HSP90AB3P HSP90BC LQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQ
Q58FF8 S58 Sugiyama HSP90AB2P HSP90BB IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 T104 Sugiyama HSP90AB2P HSP90BB LTLVDTGIGMTKADLINNLGtIAKFQDQTEYLEEMQVKEVV
Q58FF8 T60 Sugiyama HSP90AB2P HSP90BB LWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQ
Q58FG1 T28 Sugiyama HSP90AA4P HSP90AD HSPCAL2 SKLDSGKEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLG
Q58FG1 T30 Sugiyama HSP90AA4P HSP90AD HSPCAL2 LDSGKEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLGTI
Q58FG1 T34 Sugiyama HSP90AA4P HSP90AD HSPCAL2 KEPHISLIPNKQDRtLtIVDtGIGMTKADLINNLGTITKSE
Q5T0F9 S209 Sugiyama CC2D1B KIAA1836 LGD1 EAAKARRCERGLKTLESQLAsVRRGRKINEDEIPPPVALGK
Q5VTE0 T261 Sugiyama EEF1A1P5 EEF1AL3 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5VZF2 S56 Sugiyama MBNL2 MBLL MBLL39 MLP1 FAHPPKSCQVENGRVIACFDsLKGRCSRENCKYLHPPTHLK
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q66LE6 S418 Sugiyama PPP2R2D KIAA1541 LKPRKVCTGGKRRKDEIsVDsLDFNKKILHTAWHPVDNVIA
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6PEY2 T334 Sugiyama TUBA3E ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q6PEY2 T41 Sugiyama TUBA3E WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q6PEY2 T51 Sugiyama TUBA3E QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q6PEY2 T56 Sugiyama TUBA3E MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 T929 Sugiyama POTEE A26C1A POTE2 VRDIKEKLCyVALDFEQEMAtAAssssLEKsyELPDGQVIt
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36 T334 Sugiyama TUBA1A TUBA3 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q71U36 T41 Sugiyama TUBA1A TUBA3 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q71U36 T51 Sugiyama TUBA1A TUBA3 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q71U36 T56 Sugiyama TUBA1A TUBA3 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7KZF4 T779 Sugiyama SND1 TDRD11 IHVFYIDYGNREVLPSTRLGtLsPAFsTRVLPAQATEYAFA
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86V81 S8 Sugiyama ALYREF ALY BEF THOC4 _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8N0Y7 T96 Sugiyama PGAM4 PGAM3 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
Q8NBJ7 T260 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 SPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMGNtPD
Q8NBJ7 T42 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 LGNGQATSMVQLQGGRFLMGtNsPDSRDGDGPVREATVKPF
Q8NHW5 T122 Sugiyama RPLP0P6 LLANKVPAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALG
Q8NHW5 T128 Sugiyama RPLP0P6 PAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALGItTKIS
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8WXX5 S215 Sugiyama DNAJC9 EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL
Q92888 S409 Sugiyama ARHGEF1 ELEPEEPPGWRELVPPDtLHsLPKSQVKRQEVISELLVTEA
Q92888 T406 Sugiyama ARHGEF1 SGLELEPEEPPGWRELVPPDtLHsLPKSQVKRQEVISELLV
Q96AY3 T200 Sugiyama FKBP10 FKBP65 PSEC0056 HYNGTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLG
Q96AY3 T203 Sugiyama FKBP10 FKBP65 PSEC0056 GTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGMCP
Q96AY3 Y201 Sugiyama FKBP10 FKBP65 PSEC0056 YNGTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGM
Q96G46 T167 Sugiyama DUS3L VGRYLETKPADLGPRCVLFEtFGRCPYGVtCRFAGAHLRPE
Q96G46 T176 Sugiyama DUS3L ADLGPRCVLFEtFGRCPYGVtCRFAGAHLRPEGQNLVQEEL
Q96QK1 T773 Sugiyama VPS35 MEM3 TCCCTA00141 DLPNLEssEEtEQINKHFHNtLEHLRLRREsPEsEGPIyEG
Q99460 T830 Sugiyama PSMD1 TFAYPAPLEVPKEKEKEKVStAVLsItAKAKKKEKEKEKKE
Q99460 T836 Sugiyama PSMD1 PLEVPKEKEKEKVStAVLsItAKAKKKEKEKEKKEEEKMEV
Q99575 T134 Sugiyama POP1 KIAA0061 EISAMLKAVTQKssNsLVFQtLPRHMRRRAMSHNVKRLPRR
Q99613 S639 Sugiyama EIF3C EIF3S8 CAFRQGLTKDAHNALLDIQssGRAKELLGQGLLLRSLQERN
Q99613 T880 Sugiyama EIF3C EIF3S8 AEKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMR
Q99832 T57 Sugiyama CCT7 CCTH NIP7-1 RTTLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAK
Q99832 T64 Sugiyama CCT7 CCTH NIP7-1 GMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTLVDIAK
Q9BQE3 T334 Sugiyama TUBA1C TUBA6 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q9BQE3 T41 Sugiyama TUBA1C TUBA6 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q9BQE3 T51 Sugiyama TUBA1C TUBA6 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q9BQE3 T56 Sugiyama TUBA1C TUBA6 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BUF5 T312 Sugiyama TUBB6 QMFDARNMMAACDPRHGRYLtVAtVFRGPMSMKEVDEQMLA
Q9BUF5 T315 Sugiyama TUBB6 DARNMMAACDPRHGRYLtVAtVFRGPMSMKEVDEQMLAIQS
Q9BUJ2 S512 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 IQIAARKKRNyILDQtNVyGsAQRRKMRPFEGFQRKAIVIC
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9GZT8 T149 Sugiyama NIF3L1 ALS2CR1 MDS015 My018 AYDAAPQGVNNWLAKGLGACtSRPIHPSKAPNyPTEGNHRV
Q9H0A0 S593 Sugiyama NAT10 ALP KIAA1709 VLAVIQVCLEGEISRQSILNsLSRGKKASGDLIPWTVSEQF
Q9H173 T123 Sugiyama SIL1 UNQ545/PRO836 KLQYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAE
Q9H173 T125 Sugiyama SIL1 UNQ545/PRO836 QYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEME
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NQB0 S177 SIGNOR|EPSD|PSP TCF7L2 TCF4 PLLDVQAGSLQSRQALKDARsPsPAHIVsNKVPVVQHPHHV
Q9NR56 S56 Sugiyama MBNL1 EXP KIAA0428 MBNL FAHPSKSCQVENGRVIACFDsLKGRCSRENCKyLHPPPHLK
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9P0J1 T494 Sugiyama PDP1 PDP PPM2C EDQNAATHLIRHAVGNNEFGtVDHERLSKMLSLPEELARMY
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UBR2 T172 Sugiyama CTSZ ETCNNYQAKDQECDKFNQCGtCNEFKECHAIRNYTLWRVGD
Q9UBR2 Y76 Sugiyama CTSZ YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA
Q9UHD1 T204 Sugiyama CHORDC1 CHP1 IFHEGMKYWSCCRRKtsDFNtFLAQEGCtKGKHMWTKKDAG
Q9UHD1 T212 Sugiyama CHORDC1 CHP1 WSCCRRKtsDFNtFLAQEGCtKGKHMWTKKDAGKKVVPCRH
Q9UHR6 T316 Sugiyama ZNHIT2 C11orf5 GEGPTNQKGyTLAALGDLAQtLGRARKQAVAREERDHLYRA
Q9UHR6 Y305 Sugiyama ZNHIT2 C11orf5 GAMHEVARILLGEGPTNQKGyTLAALGDLAQtLGRARKQAV
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UKE5 S640 EPSD TNIK KIAA0551 SGFQEALNVTSHRVEMPRQNsDPtSENPPLPTRIEKFDRss
Q9UKE5 S680 EPSD TNIK KIAA0551 sWLRQEEDIPPKVPQRttsIsPALARKNsPGNGSALGPRLG
Q9UKE5 T181 EPSD TNIK KIAA0551 LTENAEVKLVDFGVsAQLDRtVGRRNtFIGTPYWMAPEVIA
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UQ80 T279 Sugiyama PA2G4 EBP1 MKtSRAFFsEVERRFDAMPFtLRAFEDEKKARMGVVECAKH
Q9UQ80 T386 Sugiyama PA2G4 EBP1 tQKKKKKKAsKtAENAtsGEtLEENEAGD____________
Q9UQ80 T60 Sugiyama PA2G4 EBP1 ssGVsVLsLCEKGDAMIMEEtGKIFKKEKEMKKGIAFPTSI
Q9Y230 T194 Sugiyama RUVBL2 INO80J TIP48 TIP49B CGI-46 LGTKMIESLTKDKVQAGDVItIDKAtGKISKLGRSFTRARD
Q9Y230 T459 Sugiyama RUVBL2 INO80J TIP48 TIP49B CGI-46 STQYMKEyQDAFLFNELKGEtMDTS________________
Q9Y265 S179 Sugiyama RUVBL1 INO80H NMP238 TIP49 TIP49A IGLKTAKGTKQLKLDPSIFEsLQKERVEAGDVIyIEANSGA
Q9Y2B0 T100 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL
Q9Y383 T17 Sugiyama LUC7L2 CGI-59 CGI-74 ____MSAQAQMRAMLDQLMGtsRDGDttRQRIKFSDDRVCK
Q9Y3F4 S230 Sugiyama STRAP MAWD UNRIP SAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLyKy
Q9Y3F4 T225 Sugiyama STRAP MAWD UNRIP SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF
Q9Y3F4 T48 Sugiyama STRAP MAWD UNRIP YGYFLISACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLN
Q9Y3F4 T54 Sugiyama STRAP MAWD UNRIP SACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLNKDATKA
Q9Y3U8 S91 Sugiyama RPL36 KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y4L1 S461 Sugiyama HYOU1 GRP170 HSPH4 ORP150 VVYPILVEFTREVEEEPGIHsLKHNKRVLFSRMGPYPQRKV
Q9Y5L4 T79 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B DNSEQKCIAMCMDRyMDAWNtVsRAYNSRLQRERANM____
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Apoptotic execution phase R-HSA-75153 5.637436e-08 7.249 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 5.120000e-07 6.291 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.742544e-05 4.759 0 0
Axon guidance R-HSA-422475 4.623751e-05 4.335 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 8.816239e-05 4.055 0 0
Nervous system development R-HSA-9675108 9.337678e-05 4.030 0 0
Signaling by ERBB2 R-HSA-1227986 1.076576e-04 3.968 0 0
Signaling by Hippo R-HSA-2028269 2.783608e-04 3.555 0 0
Long-term potentiation R-HSA-9620244 2.741968e-04 3.562 0 0
Signal Transduction R-HSA-162582 2.660000e-04 3.575 0 0
Oncogenic MAPK signaling R-HSA-6802957 4.138093e-04 3.383 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 4.765066e-04 3.322 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 5.091181e-04 3.293 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 8.258476e-04 3.083 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 7.833370e-04 3.106 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 8.068662e-04 3.093 0 0
L1CAM interactions R-HSA-373760 8.324060e-04 3.080 0 0
EPH-Ephrin signaling R-HSA-2682334 9.152236e-04 3.038 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.037575e-03 2.984 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.048075e-03 2.980 0 0
Cell-Cell communication R-HSA-1500931 1.102103e-03 2.958 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.375972e-03 2.861 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.621575e-03 2.790 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.621173e-03 2.790 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.602704e-03 2.795 0 0
Signal attenuation R-HSA-74749 1.902924e-03 2.721 0 0
Regulation of CDH11 function R-HSA-9762292 1.902924e-03 2.721 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.902924e-03 2.721 0 0
MAPK family signaling cascades R-HSA-5683057 1.816895e-03 2.741 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.230181e-03 2.652 0 0
Semaphorin interactions R-HSA-373755 2.366695e-03 2.626 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.133009e-03 2.671 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 2.366695e-03 2.626 0 0
Signaling by PTK6 R-HSA-8848021 2.366695e-03 2.626 0 0
Cell junction organization R-HSA-446728 2.144818e-03 2.669 0 0
Ephrin signaling R-HSA-3928664 2.397474e-03 2.620 0 0
Apoptosis R-HSA-109581 2.589019e-03 2.587 0 0
IRS activation R-HSA-74713 2.843232e-03 2.546 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.843232e-03 2.546 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 2.946410e-03 2.531 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 2.946410e-03 2.531 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.377038e-03 2.471 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.377038e-03 2.471 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.122803e-03 2.385 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.122803e-03 2.385 0 0
Signaling by LTK R-HSA-9842663 3.981694e-03 2.400 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.122803e-03 2.385 0 0
Programmed Cell Death R-HSA-5357801 4.334083e-03 2.363 0 0
Signaling by VEGF R-HSA-194138 4.400913e-03 2.356 0 0
Integrin signaling R-HSA-354192 4.950953e-03 2.305 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 4.950953e-03 2.305 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 5.088821e-03 2.293 0 0
Post NMDA receptor activation events R-HSA-438064 5.499927e-03 2.260 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 6.203395e-03 2.207 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 6.203395e-03 2.207 0 0
Signaling downstream of RAS mutants R-HSA-9649948 6.203395e-03 2.207 0 0
Signaling by RAS mutants R-HSA-6802949 6.203395e-03 2.207 0 0
Kinesins R-HSA-983189 6.243672e-03 2.205 0 0
RAF activation R-HSA-5673000 6.263046e-03 2.203 0 0
Cellular Senescence R-HSA-2559583 6.597212e-03 2.181 1 0
Cell-extracellular matrix interactions R-HSA-446353 7.222948e-03 2.141 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 7.599924e-03 2.119 0 0
Tight junction interactions R-HSA-420029 8.272048e-03 2.082 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 8.680878e-03 2.061 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 9.828105e-03 2.008 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 9.828105e-03 2.008 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 9.318319e-03 2.031 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.014105e-02 1.994 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.014105e-02 1.994 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.061571e-02 1.974 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.119207e-02 1.951 0 0
Cell Cycle, Mitotic R-HSA-69278 1.142141e-02 1.942 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.184892e-02 1.926 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.239779e-02 1.907 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.285758e-02 1.891 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.408921e-02 1.851 0 0
MAP2K and MAPK activation R-HSA-5674135 1.408921e-02 1.851 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.531672e-02 1.815 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.574313e-02 1.803 1 1
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.574313e-02 1.803 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.466096e-02 1.834 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.640327e-02 1.785 0 0
Signaling by ERBB4 R-HSA-1236394 1.750413e-02 1.757 0 0
Formation of definitive endoderm R-HSA-9823730 1.803912e-02 1.744 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.803912e-02 1.744 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.859011e-02 1.731 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.983767e-02 1.703 0 0
Interleukin-12 signaling R-HSA-9020591 1.986333e-02 1.702 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.030806e-02 1.692 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 2.222084e-02 1.653 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.310237e-02 1.636 0 0
Recycling pathway of L1 R-HSA-437239 2.323562e-02 1.634 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.391681e-02 1.621 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.415405e-02 1.617 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 2.620972e-02 1.582 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.764977e-02 1.558 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.828521e-02 1.548 0 0
ESR-mediated signaling R-HSA-8939211 2.897918e-02 1.538 0 0
Formation of axial mesoderm R-HSA-9796292 3.055570e-02 1.515 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 3.138401e-02 1.503 0 0
Neuronal System R-HSA-112316 3.418238e-02 1.466 0 0
NrCAM interactions R-HSA-447038 3.172916e-02 1.499 0 0
Signaling by NTRKs R-HSA-166520 3.463764e-02 1.460 0 0
Intracellular signaling by second messengers R-HSA-9006925 3.280824e-02 1.484 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.299891e-02 1.482 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 3.510580e-02 1.455 0 0
Amplification of signal from the kinetochores R-HSA-141424 3.510580e-02 1.455 0 0
Regulation of KIT signaling R-HSA-1433559 3.525603e-02 1.453 0 0
HDMs demethylate histones R-HSA-3214842 3.559500e-02 1.449 0 0
Cell Cycle R-HSA-1640170 3.585728e-02 1.445 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 4.015095e-02 1.396 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.039638e-02 1.394 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.039638e-02 1.394 0 0
Signaling by ALK R-HSA-201556 3.719387e-02 1.430 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.923551e-02 1.406 0 0
XBP1(S) activates chaperone genes R-HSA-381038 3.697047e-02 1.432 0 0
Interleukin-12 family signaling R-HSA-447115 3.890062e-02 1.410 0 0
Mitotic Prophase R-HSA-68875 4.264366e-02 1.370 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 4.570138e-02 1.340 0 0
mRNA Splicing - Major Pathway R-HSA-72163 4.639876e-02 1.333 0 0
Signaling by EGFR R-HSA-177929 4.328964e-02 1.364 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 4.570138e-02 1.340 0 0
Killing mechanisms R-HSA-9664420 4.570138e-02 1.340 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 4.582062e-02 1.339 0 0
Pyroptosis R-HSA-5620971 4.708527e-02 1.327 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 4.812546e-02 1.318 0 0
PKMTs methylate histone lysines R-HSA-3214841 4.324682e-02 1.364 0 0
Nuclear Envelope Breakdown R-HSA-2980766 4.602592e-02 1.337 0 0
Cell-cell junction organization R-HSA-421270 4.381336e-02 1.358 0 0
MHC class II antigen presentation R-HSA-2132295 4.812546e-02 1.318 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 4.920517e-02 1.308 0 0
Signaling by ALK in cancer R-HSA-9700206 4.920517e-02 1.308 0 0
IRE1alpha activates chaperones R-HSA-381070 4.955872e-02 1.305 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.984090e-02 1.302 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.132082e-02 1.290 0 0
SOS-mediated signalling R-HSA-112412 5.998983e-02 1.222 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 5.749661e-02 1.240 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 5.358760e-02 1.271 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 5.998983e-02 1.222 0 0
Regulation of PTEN gene transcription R-HSA-8943724 5.486782e-02 1.261 0 0
Netrin-1 signaling R-HSA-373752 5.703018e-02 1.244 0 0
M Phase R-HSA-68886 5.266867e-02 1.278 0 0
Membrane Trafficking R-HSA-199991 5.784156e-02 1.238 0 0
MECP2 regulates transcription factors R-HSA-9022707 5.998983e-02 1.222 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 5.571475e-02 1.254 0 0
Sensory processing of sound R-HSA-9659379 5.956941e-02 1.225 0 0
Interleukin-37 signaling R-HSA-9008059 5.575773e-02 1.254 0 0
Trafficking of AMPA receptors R-HSA-399719 6.039451e-02 1.219 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.248914e-02 1.204 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 6.388036e-02 1.195 0 0
Synaptic adhesion-like molecules R-HSA-8849932 6.388036e-02 1.195 0 0
mRNA Splicing R-HSA-72172 6.439575e-02 1.191 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 6.463888e-02 1.190 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 6.466797e-02 1.189 0 0
Signaling by TGFBR3 R-HSA-9839373 6.476387e-02 1.189 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 7.584197e-02 1.120 0 0
Diseases of Telomere Maintenance R-HSA-9673013 7.584197e-02 1.120 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 7.584197e-02 1.120 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 7.584197e-02 1.120 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 7.584197e-02 1.120 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 7.584197e-02 1.120 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 7.584197e-02 1.120 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 7.584197e-02 1.120 0 0
Type I hemidesmosome assembly R-HSA-446107 7.077477e-02 1.150 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 7.025967e-02 1.153 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 7.025967e-02 1.153 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 7.548305e-02 1.122 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 7.548305e-02 1.122 0 0
IGF1R signaling cascade R-HSA-2428924 6.814842e-02 1.167 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 7.173560e-02 1.144 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 7.542928e-02 1.122 0 0
Inhibition of PKR R-HSA-169131 7.584197e-02 1.120 0 0
STING mediated induction of host immune responses R-HSA-1834941 7.057576e-02 1.151 0 0
GPER1 signaling R-HSA-9634597 7.305533e-02 1.136 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.218560e-02 1.142 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 7.077477e-02 1.150 0 0
Mitotic Spindle Checkpoint R-HSA-69618 7.611703e-02 1.119 0 0
Degradation of CDH1 R-HSA-9766229 7.740824e-02 1.111 0 0
Protein-protein interactions at synapses R-HSA-6794362 7.837683e-02 1.106 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 8.008511e-02 1.096 0 0
SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-3315487 1.115811e-01 0.952 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 1.115811e-01 0.952 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 1.115811e-01 0.952 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 1.115811e-01 0.952 0 0
Loss of Function of SMAD4 in Cancer R-HSA-3304347 1.115811e-01 0.952 0 0
SMAD4 MH2 Domain Mutants in Cancer R-HSA-3311021 1.115811e-01 0.952 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.459403e-01 0.836 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.459403e-01 0.836 0 0
Defective PAPSS2 causes SEMD-PA R-HSA-3560796 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.459403e-01 0.836 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.459403e-01 0.836 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.459403e-01 0.836 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.789726e-01 0.747 0 0
Classical Kir channels R-HSA-1296053 1.789726e-01 0.747 0 0
HCN channels R-HSA-1296061 2.107293e-01 0.676 0 0
ATP sensitive Potassium channels R-HSA-1296025 2.107293e-01 0.676 0 0
Nucleotide catabolism defects R-HSA-9735786 2.107293e-01 0.676 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.107293e-01 0.676 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.107293e-01 0.676 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 2.107293e-01 0.676 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 2.107293e-01 0.676 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.107293e-01 0.676 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 9.399994e-02 1.027 0 0
Folding of actin by CCT/TriC R-HSA-390450 9.399994e-02 1.027 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.063236e-01 0.973 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.063236e-01 0.973 0 0
Activation of AMPA receptors R-HSA-399710 2.412596e-01 0.618 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.412596e-01 0.618 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 2.412596e-01 0.618 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.190496e-01 0.924 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.190496e-01 0.924 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.190496e-01 0.924 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.321286e-01 0.879 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 2.706106e-01 0.568 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.706106e-01 0.568 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.706106e-01 0.568 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 1.455145e-01 0.837 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 8.486011e-02 1.071 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 9.242701e-02 1.034 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.242701e-02 1.034 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.591639e-01 0.798 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.988280e-01 0.525 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.988280e-01 0.525 0 0
Notch-HLH transcription pathway R-HSA-350054 1.002616e-01 0.999 0 0
Erythropoietin activates RAS R-HSA-9027284 1.730366e-01 0.762 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.730366e-01 0.762 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.730366e-01 0.762 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.730366e-01 0.762 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 3.259554e-01 0.487 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 3.259554e-01 0.487 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.259554e-01 0.487 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 3.259554e-01 0.487 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 1.430240e-01 0.845 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.520348e-01 0.453 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.520348e-01 0.453 0 0
Activation of RAS in B cells R-HSA-1169092 3.520348e-01 0.453 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.106844e-01 0.956 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.300460e-01 0.638 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.171569e-01 0.931 0 0
mRNA 3'-end processing R-HSA-72187 9.128150e-02 1.040 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.711028e-01 0.767 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.771068e-01 0.424 0 0
WNT mediated activation of DVL R-HSA-201688 3.771068e-01 0.424 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.807908e-01 0.743 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.807908e-01 0.743 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 8.714501e-02 1.060 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 2.005857e-01 0.698 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 2.735457e-01 0.563 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.012101e-01 0.397 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.042219e-01 0.982 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 2.880498e-01 0.541 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.880498e-01 0.541 0 0
Centrosome maturation R-HSA-380287 1.133674e-01 0.946 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.311474e-01 0.636 0 0
FGFR2 alternative splicing R-HSA-6803529 3.025202e-01 0.519 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.025202e-01 0.519 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 4.243821e-01 0.372 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.169378e-01 0.499 0 0
Voltage gated Potassium channels R-HSA-1296072 2.519682e-01 0.599 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 3.312850e-01 0.480 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 3.312850e-01 0.480 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 4.466587e-01 0.350 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 4.466587e-01 0.350 0 0
Signaling by GSK3beta mutants R-HSA-5339716 4.466587e-01 0.350 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 2.836540e-01 0.547 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 4.680746e-01 0.330 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.680746e-01 0.330 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 4.680746e-01 0.330 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 4.680746e-01 0.330 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 4.680746e-01 0.330 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 4.680746e-01 0.330 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 4.680746e-01 0.330 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 3.737505e-01 0.427 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 3.737505e-01 0.427 0 0
snRNP Assembly R-HSA-191859 2.730128e-01 0.564 0 0
Metabolism of non-coding RNA R-HSA-194441 2.730128e-01 0.564 0 0
Signaling by Erythropoietin R-HSA-9006335 4.014483e-01 0.396 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 3.079167e-01 0.512 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 3.079167e-01 0.512 0 0
AURKA Activation by TPX2 R-HSA-8854518 3.343811e-01 0.476 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 4.418624e-01 0.355 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 3.786350e-01 0.422 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 4.215678e-01 0.375 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.319159e-01 0.365 0 0
HDACs deacetylate histones R-HSA-3214815 4.524026e-01 0.344 0 0
Post-translational protein phosphorylation R-HSA-8957275 4.294224e-01 0.367 0 0
Signaling by EGFR in Cancer R-HSA-1643713 3.597055e-01 0.444 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.735457e-01 0.563 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.735457e-01 0.563 0 0
Signaling by NOTCH2 R-HSA-1980145 4.807246e-01 0.318 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.156311e-01 0.666 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.156311e-01 0.666 0 0
DAP12 signaling R-HSA-2424491 4.150798e-01 0.382 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.735457e-01 0.563 0 0
EGFR downregulation R-HSA-182971 4.285539e-01 0.368 0 0
Neutrophil degranulation R-HSA-6798695 3.383272e-01 0.471 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 3.597055e-01 0.444 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 2.171955e-01 0.663 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 3.786350e-01 0.422 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.820066e-01 0.740 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 4.140846e-01 0.383 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.519682e-01 0.599 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 4.285539e-01 0.368 0 0
GAB1 signalosome R-HSA-180292 2.300460e-01 0.638 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 4.625315e-01 0.335 0 0
PI3K/AKT activation R-HSA-198203 9.399994e-02 1.027 0 0
Signalling to RAS R-HSA-167044 8.486011e-02 1.071 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.666717e-01 0.778 0 0
RAB geranylgeranylation R-HSA-8873719 1.339376e-01 0.873 0 0
Myogenesis R-HSA-525793 1.340345e-01 0.873 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.208597e-01 0.656 0 0
RNA Polymerase I Transcription R-HSA-73864 4.399677e-01 0.357 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.742808e-01 0.759 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 4.418624e-01 0.355 0 0
Insulin receptor signalling cascade R-HSA-74751 3.167195e-01 0.499 0 0
Regulation of gap junction activity R-HSA-191650 2.107293e-01 0.676 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.455145e-01 0.837 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 2.013040e-01 0.696 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.522070e-01 0.818 0 0
Separation of Sister Chromatids R-HSA-2467813 2.936226e-01 0.532 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.571940e-01 0.340 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.445205e-01 0.612 0 0
Adipogenesis R-HSA-9843745 2.278088e-01 0.642 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 4.807246e-01 0.318 0 0
Developmental Cell Lineages R-HSA-9734767 4.399597e-01 0.357 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.680746e-01 0.330 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.737505e-01 0.427 0 0
Inwardly rectifying K+ channels R-HSA-1296065 4.418624e-01 0.355 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 1.764851e-01 0.753 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.225854e-01 0.374 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 4.063913e-01 0.391 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.107293e-01 0.676 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.412596e-01 0.618 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 2.412596e-01 0.618 0 0
DCC mediated attractive signaling R-HSA-418885 1.730366e-01 0.762 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.730366e-01 0.762 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 3.520348e-01 0.453 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.838267e-01 0.736 0 0
GRB2 events in EGFR signaling R-HSA-179812 4.680746e-01 0.330 0 0
Defective pyroptosis R-HSA-9710421 3.263369e-01 0.486 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.226236e-01 0.911 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 2.821561e-01 0.550 0 0
Parasite infection R-HSA-9664407 2.821561e-01 0.550 0 0
Leishmania phagocytosis R-HSA-9664417 2.821561e-01 0.550 0 0
Meiotic synapsis R-HSA-1221632 4.319159e-01 0.365 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.048017e-01 0.516 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 2.013040e-01 0.696 0 0
Neurexins and neuroligins R-HSA-6794361 2.139596e-01 0.670 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 8.213154e-02 1.085 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 3.874663e-01 0.412 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.412596e-01 0.618 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.706106e-01 0.568 0 0
p38MAPK events R-HSA-171007 1.730366e-01 0.762 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 1.730366e-01 0.762 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 3.259554e-01 0.487 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.771068e-01 0.424 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.597055e-01 0.444 0 0
Diseases of mitotic cell cycle R-HSA-9675126 4.418624e-01 0.355 0 0
Nuclear RNA decay R-HSA-9930044 4.549979e-01 0.342 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 1.340778e-01 0.873 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 1.171569e-01 0.931 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 1.171569e-01 0.931 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.466587e-01 0.350 0 0
Mitophagy R-HSA-5205647 8.089638e-02 1.092 0 0
Regulation of CDH1 Function R-HSA-9764561 1.170191e-01 0.932 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.771068e-01 0.424 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.166859e-01 0.933 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 3.365720e-01 0.473 0 0
PCP/CE pathway R-HSA-4086400 4.399677e-01 0.357 0 0
Signaling by SCF-KIT R-HSA-1433557 3.263369e-01 0.486 0 0
Signalling to ERKs R-HSA-187687 8.649630e-02 1.063 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 4.014483e-01 0.396 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.115811e-01 0.952 0 0
Manipulation of host energy metabolism R-HSA-9636667 1.115811e-01 0.952 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.115811e-01 0.952 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.063236e-01 0.973 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.412596e-01 0.618 0 0
Suppression of autophagy R-HSA-9636569 2.412596e-01 0.618 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.190496e-01 0.924 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 2.706106e-01 0.568 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.706106e-01 0.568 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.706106e-01 0.568 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.455145e-01 0.837 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.455145e-01 0.837 0 0
G2/M DNA replication checkpoint R-HSA-69478 2.988280e-01 0.525 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.259554e-01 0.487 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 1.252509e-01 0.902 0 0
FGFR1b ligand binding and activation R-HSA-190370 3.520348e-01 0.453 0 0
HSF1-dependent transactivation R-HSA-3371571 8.652273e-02 1.063 0 0
Signaling by NODAL R-HSA-1181150 2.590284e-01 0.587 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 4.012101e-01 0.397 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 4.012101e-01 0.397 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 4.012101e-01 0.397 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 4.012101e-01 0.397 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 4.012101e-01 0.397 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.169378e-01 0.499 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 2.519682e-01 0.599 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.207981e-01 0.918 0 0
Deadenylation of mRNA R-HSA-429947 3.312850e-01 0.480 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.466587e-01 0.350 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.466587e-01 0.350 0 0
Plasmalogen biosynthesis R-HSA-75896 4.466587e-01 0.350 0 0
Potassium Channels R-HSA-1296071 1.340778e-01 0.873 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 4.680746e-01 0.330 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.680746e-01 0.330 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.680746e-01 0.330 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.876684e-01 0.412 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 4.014483e-01 0.396 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 3.477032e-01 0.459 0 0
Budding and maturation of HIV virion R-HSA-162588 4.285539e-01 0.368 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.369603e-01 0.472 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.561050e-01 0.592 0 0
Mitotic Prometaphase R-HSA-68877 2.201992e-01 0.657 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 3.156472e-01 0.501 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.518271e-01 0.819 0 0
rRNA processing R-HSA-72312 2.951599e-01 0.530 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.715700e-01 0.430 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 4.680746e-01 0.330 0 0
Mitotic Anaphase R-HSA-68882 1.460452e-01 0.836 0 0
Signaling by NOTCH1 R-HSA-1980143 4.225854e-01 0.374 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 8.213154e-02 1.085 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.412596e-01 0.618 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 3.520348e-01 0.453 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 4.679539e-01 0.330 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.492181e-01 0.826 0 0
Oncogene Induced Senescence R-HSA-2559585 8.649630e-02 1.063 0 0
RET signaling R-HSA-8853659 9.227914e-02 1.035 0 0
Cargo concentration in the ER R-HSA-5694530 4.285539e-01 0.368 0 0
Signaling by TGFB family members R-HSA-9006936 2.726980e-01 0.564 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.049643e-01 0.516 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 1.591639e-01 0.798 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.430240e-01 0.845 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 3.771068e-01 0.424 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 4.012101e-01 0.397 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 2.106687e-01 0.676 0 0
MET activates RAS signaling R-HSA-8851805 4.680746e-01 0.330 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.874663e-01 0.412 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 9.242701e-02 1.034 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 2.208597e-01 0.656 0 0
Platelet activation, signaling and aggregation R-HSA-76002 3.772210e-01 0.423 0 0
Regulation of BACH1 activity R-HSA-9708530 1.870950e-01 0.728 0 0
TGFBR3 expression R-HSA-9839394 1.252509e-01 0.902 0 0
Smooth Muscle Contraction R-HSA-445355 2.221808e-01 0.653 0 0
Acyl chain remodelling of PS R-HSA-1482801 3.455459e-01 0.461 0 0
Formation of the cornified envelope R-HSA-6809371 4.614150e-01 0.336 0 0
Parasitic Infection Pathways R-HSA-9824443 3.036473e-01 0.518 0 0
Leishmania infection R-HSA-9658195 3.036473e-01 0.518 0 0
Interleukin-15 signaling R-HSA-8983432 4.680746e-01 0.330 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 4.545809e-01 0.342 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.480475e-01 0.830 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.156472e-01 0.501 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.115811e-01 0.952 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.789726e-01 0.747 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 1.789726e-01 0.747 0 0
GP1b-IX-V activation signalling R-HSA-430116 8.213154e-02 1.085 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 8.213154e-02 1.085 0 0
NADE modulates death signalling R-HSA-205025 2.107293e-01 0.676 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.412596e-01 0.618 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.706106e-01 0.568 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.259554e-01 0.487 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.259554e-01 0.487 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.520348e-01 0.453 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 3.520348e-01 0.453 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 3.520348e-01 0.453 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.106844e-01 0.956 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.106844e-01 0.956 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.300460e-01 0.638 0 0
ARMS-mediated activation R-HSA-170984 3.771068e-01 0.424 0 0
Regulation of signaling by NODAL R-HSA-1433617 3.771068e-01 0.424 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 1.807908e-01 0.743 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 4.012101e-01 0.397 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.208597e-01 0.656 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 3.876684e-01 0.412 0 0
Late endosomal microautophagy R-HSA-9615710 4.014483e-01 0.396 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.686595e-01 0.571 0 0
Selective autophagy R-HSA-9663891 3.369272e-01 0.472 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 3.986854e-01 0.399 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.972475e-01 0.705 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.321605e-01 0.634 0 0
Adherens junctions interactions R-HSA-418990 2.346159e-01 0.630 0 0
Cellular responses to stress R-HSA-2262752 1.461945e-01 0.835 1 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.684435e-01 0.774 0 0
Autophagy R-HSA-9612973 2.522399e-01 0.598 0 0
Developmental Biology R-HSA-1266738 2.004304e-01 0.698 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 2.308064e-01 0.637 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 2.308064e-01 0.637 0 0
Metabolism of RNA R-HSA-8953854 3.698087e-01 0.432 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 3.792780e-01 0.421 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.706106e-01 0.568 0 0
Vesicle-mediated transport R-HSA-5653656 3.635974e-01 0.439 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.055736e-01 0.687 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 3.597055e-01 0.444 0 0
G1 Phase R-HSA-69236 3.370249e-01 0.472 0 0
Cyclin D associated events in G1 R-HSA-69231 3.370249e-01 0.472 0 0
Chromatin modifying enzymes R-HSA-3247509 1.349744e-01 0.870 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 4.399677e-01 0.357 0 0
Histamine receptors R-HSA-390650 1.789726e-01 0.747 0 0
PECAM1 interactions R-HSA-210990 1.063236e-01 0.973 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 9.242701e-02 1.034 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 2.988280e-01 0.525 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.988280e-01 0.525 0 0
Rap1 signalling R-HSA-392517 2.445205e-01 0.612 0 0
Nuclear import of Rev protein R-HSA-180746 2.208597e-01 0.656 0 0
NRAGE signals death through JNK R-HSA-193648 2.473091e-01 0.607 0 0
TBC/RABGAPs R-HSA-8854214 3.263369e-01 0.486 0 0
tRNA processing in the nucleus R-HSA-6784531 2.991393e-01 0.524 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 4.549979e-01 0.342 0 0
Regulated Necrosis R-HSA-5218859 1.838267e-01 0.736 0 0
Transmission across Chemical Synapses R-HSA-112315 1.383672e-01 0.859 0 0
Cellular responses to stimuli R-HSA-8953897 1.588532e-01 0.799 1 0
Cellular response to heat stress R-HSA-3371556 1.684435e-01 0.774 0 0
Spry regulation of FGF signaling R-HSA-1295596 1.730366e-01 0.762 0 0
Interleukin-2 family signaling R-HSA-451927 2.836540e-01 0.547 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.466587e-01 0.350 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.168610e-01 0.932 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.459403e-01 0.836 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 1.789726e-01 0.747 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.107293e-01 0.676 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.412596e-01 0.618 0 0
Co-inhibition by BTLA R-HSA-9927353 2.412596e-01 0.618 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.706106e-01 0.568 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 1.870950e-01 0.728 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.259554e-01 0.487 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 3.259554e-01 0.487 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 3.259554e-01 0.487 0 0
Netrin mediated repulsion signals R-HSA-418886 3.259554e-01 0.487 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.771068e-01 0.424 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 4.012101e-01 0.397 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.880498e-01 0.541 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.398078e-01 0.854 0 0
mTORC1-mediated signalling R-HSA-166208 3.025202e-01 0.519 0 0
Bicarbonate transporters R-HSA-425381 4.243821e-01 0.372 0 0
Activation of RAC1 R-HSA-428540 4.466587e-01 0.350 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 2.836540e-01 0.547 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 2.836540e-01 0.547 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 2.942969e-01 0.531 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.680746e-01 0.330 0 0
Regulation of IFNG signaling R-HSA-877312 4.680746e-01 0.330 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 4.680746e-01 0.330 0 0
Neurotransmitter clearance R-HSA-112311 4.150798e-01 0.382 0 0
Signaling by FGFR2 R-HSA-5654738 1.379203e-01 0.860 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.597055e-01 0.444 0 0
Chromatin organization R-HSA-4839726 1.820123e-01 0.740 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.972475e-01 0.705 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.285539e-01 0.368 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 4.522686e-01 0.345 0 0
Neurodegenerative Diseases R-HSA-8863678 1.166859e-01 0.933 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.166859e-01 0.933 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.447549e-01 0.462 0 0
FOXO-mediated transcription R-HSA-9614085 1.480446e-01 0.830 0 0
Effects of PIP2 hydrolysis R-HSA-114508 4.679539e-01 0.330 0 0
Glycolysis R-HSA-70171 1.528475e-01 0.816 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 3.167195e-01 0.499 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.040817e-01 0.690 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.727607e-01 0.763 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 2.836540e-01 0.547 0 0
Diseases of Immune System R-HSA-5260271 2.836540e-01 0.547 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 3.876684e-01 0.412 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 4.014483e-01 0.396 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 4.807246e-01 0.318 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.853361e-01 0.732 0 0
Interleukin-2 signaling R-HSA-9020558 1.063236e-01 0.973 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.430240e-01 0.845 0 0
G2/M Transition R-HSA-69275 2.930989e-01 0.533 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 2.706106e-01 0.568 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 2.706106e-01 0.568 0 0
Signal regulatory protein family interactions R-HSA-391160 1.591639e-01 0.798 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 2.988280e-01 0.525 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 3.259554e-01 0.487 0 0
Synthesis of PG R-HSA-1483148 2.013040e-01 0.696 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 3.771068e-01 0.424 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.771068e-01 0.424 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.771068e-01 0.424 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 3.025202e-01 0.519 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.243821e-01 0.372 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 4.243821e-01 0.372 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.624798e-01 0.581 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.098210e-01 0.959 0 0
Intra-Golgi traffic R-HSA-6811438 3.049643e-01 0.516 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.583640e-01 0.446 0 0
Ub-specific processing proteases R-HSA-5689880 2.308064e-01 0.637 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 4.549979e-01 0.342 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.030767e-01 0.518 0 0
Diseases of programmed cell death R-HSA-9645723 1.876309e-01 0.727 0 0
Signaling by FGFR1 R-HSA-5654736 1.116193e-01 0.952 0 0
Downstream signal transduction R-HSA-186763 4.285539e-01 0.368 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 2.735457e-01 0.563 0 0
Deubiquitination R-HSA-5688426 2.028197e-01 0.693 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 2.326550e-01 0.633 0 0
Ion channel transport R-HSA-983712 4.358348e-01 0.361 0 0
Apoptotic factor-mediated response R-HSA-111471 2.300460e-01 0.638 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 8.486011e-02 1.071 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.179798e-01 0.662 0 0
Signaling by FGFR R-HSA-190236 1.433145e-01 0.844 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 4.014483e-01 0.396 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 4.150798e-01 0.382 0 0
Signaling by FGFR4 R-HSA-5654743 1.446030e-01 0.840 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 4.680746e-01 0.330 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 4.680746e-01 0.330 0 0
Miscellaneous transport and binding events R-HSA-5223345 4.679539e-01 0.330 0 0
Signaling by FGFR3 R-HSA-5654741 1.591852e-01 0.798 0 0
Signaling by NOTCH3 R-HSA-9012852 4.524026e-01 0.344 0 0
PTEN Regulation R-HSA-6807070 4.181575e-01 0.379 0 0
Cell Cycle Checkpoints R-HSA-69620 3.062205e-01 0.514 0 0
Stimuli-sensing channels R-HSA-2672351 3.369603e-01 0.472 0 0
Glucose metabolism R-HSA-70326 2.619258e-01 0.582 0 0
Cardiogenesis R-HSA-9733709 4.549979e-01 0.342 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 2.412596e-01 0.618 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.730366e-01 0.762 0 0
TRP channels R-HSA-3295583 1.340345e-01 0.873 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 3.520348e-01 0.453 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 3.771068e-01 0.424 0 0
Receptor Mediated Mitophagy R-HSA-8934903 4.012101e-01 0.397 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.549979e-01 0.342 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.678332e-01 0.775 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 2.735457e-01 0.563 0 0
Response of Mtb to phagocytosis R-HSA-9637690 3.263369e-01 0.486 0 0
G alpha (12/13) signalling events R-HSA-416482 4.399677e-01 0.357 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.430240e-01 0.845 0 0
Assembly Of The HIV Virion R-HSA-175474 2.880498e-01 0.541 0 0
TNF signaling R-HSA-75893 4.625315e-01 0.335 0 0
Suppression of phagosomal maturation R-HSA-9637687 3.597055e-01 0.444 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 2.005857e-01 0.698 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.083520e-01 0.965 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.735457e-01 0.563 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.680746e-01 0.330 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 3.737505e-01 0.427 0 0
Growth hormone receptor signaling R-HSA-982772 1.083520e-01 0.965 0 0
Signaling by Leptin R-HSA-2586552 9.399994e-02 1.027 0 0
Co-stimulation by CD28 R-HSA-389356 3.796038e-01 0.421 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.242701e-02 1.034 0 0
Death Receptor Signaling R-HSA-73887 3.687528e-01 0.433 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.466587e-01 0.350 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.370617e-01 0.359 0 0
Interleukin-7 signaling R-HSA-1266695 3.455459e-01 0.461 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 4.811487e-01 0.318 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 4.825386e-01 0.316 0 0
Signaling by Interleukins R-HSA-449147 4.854927e-01 0.314 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 4.886628e-01 0.311 0 0
Adenylate cyclase activating pathway R-HSA-170660 4.886628e-01 0.311 0 0
Frs2-mediated activation R-HSA-170968 4.886628e-01 0.311 0 0
Diseases of nucleotide metabolism R-HSA-9735804 4.886628e-01 0.311 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 4.886628e-01 0.311 0 0
FGFR1c ligand binding and activation R-HSA-190373 4.886628e-01 0.311 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 4.886628e-01 0.311 0 0
Maturation of nucleoprotein R-HSA-9683610 4.886628e-01 0.311 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 4.886628e-01 0.311 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 4.886628e-01 0.311 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 4.910772e-01 0.309 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 4.910772e-01 0.309 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 4.924086e-01 0.308 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 4.933050e-01 0.307 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 4.933050e-01 0.307 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 4.933050e-01 0.307 0 0
SARS-CoV-1-host interactions R-HSA-9692914 4.971487e-01 0.304 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 4.997136e-01 0.301 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.021848e-01 0.299 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.021848e-01 0.299 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.021848e-01 0.299 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.021848e-01 0.299 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.021848e-01 0.299 0 0
tRNA Aminoacylation R-HSA-379724 5.021848e-01 0.299 0 0
Gene Silencing by RNA R-HSA-211000 5.044983e-01 0.297 0 0
PRC2 methylates histones and DNA R-HSA-212300 5.056907e-01 0.296 0 0
GPVI-mediated activation cascade R-HSA-114604 5.056907e-01 0.296 0 0
RUNX2 regulates bone development R-HSA-8941326 5.056907e-01 0.296 0 0
Calmodulin induced events R-HSA-111933 5.056907e-01 0.296 0 0
CaM pathway R-HSA-111997 5.056907e-01 0.296 0 0
Regulation of TP53 Degradation R-HSA-6804757 5.056907e-01 0.296 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.084554e-01 0.294 0 0
Removal of the Flap Intermediate R-HSA-69166 5.084554e-01 0.294 0 0
Non-canonical inflammasome activation R-HSA-9686114 5.084554e-01 0.294 0 0
HDL assembly R-HSA-8963896 5.084554e-01 0.294 0 0
Zinc transporters R-HSA-435354 5.084554e-01 0.294 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.084554e-01 0.294 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.118637e-01 0.291 0 0
Viral Messenger RNA Synthesis R-HSA-168325 5.118637e-01 0.291 0 0
Collagen degradation R-HSA-1442490 5.118637e-01 0.291 0 0
SARS-CoV-2-host interactions R-HSA-9705683 5.149758e-01 0.288 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 5.178778e-01 0.286 0 0
Ovarian tumor domain proteases R-HSA-5689896 5.178778e-01 0.286 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 5.180621e-01 0.286 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 5.180621e-01 0.286 0 0
Influenza Infection R-HSA-168255 5.206266e-01 0.283 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 5.214421e-01 0.283 0 0
Chaperonin-mediated protein folding R-HSA-390466 5.240529e-01 0.281 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 5.241247e-01 0.281 0 0
Adaptive Immune System R-HSA-1280218 5.274439e-01 0.278 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.274830e-01 0.278 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.274830e-01 0.278 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 5.274830e-01 0.278 0 0
Transport and metabolism of PAPS R-HSA-174362 5.274830e-01 0.278 0 0
Signaling by Activin R-HSA-1502540 5.274830e-01 0.278 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 5.274830e-01 0.278 0 0
Processive synthesis on the lagging strand R-HSA-69183 5.274830e-01 0.278 0 0
MET promotes cell motility R-HSA-8875878 5.298633e-01 0.276 0 0
Purine salvage R-HSA-74217 5.298633e-01 0.276 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 5.298633e-01 0.276 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 5.298633e-01 0.276 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 5.321366e-01 0.274 0 0
Peptide chain elongation R-HSA-156902 5.321366e-01 0.274 0 0
Ion transport by P-type ATPases R-HSA-936837 5.402864e-01 0.267 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 5.416445e-01 0.266 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 5.416445e-01 0.266 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 5.416445e-01 0.266 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.457752e-01 0.263 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.457752e-01 0.263 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.457752e-01 0.263 0 0
Prolonged ERK activation events R-HSA-169893 5.457752e-01 0.263 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.457752e-01 0.263 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.457752e-01 0.263 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.457752e-01 0.263 0 0
Activation of SMO R-HSA-5635838 5.457752e-01 0.263 0 0
Negative regulation of FLT3 R-HSA-9706369 5.457752e-01 0.263 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 5.457752e-01 0.263 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 5.480970e-01 0.261 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 5.532192e-01 0.257 0 0
Attenuation phase R-HSA-3371568 5.532192e-01 0.257 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 5.559698e-01 0.255 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 5.559698e-01 0.255 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.604501e-01 0.251 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 5.616216e-01 0.251 0 0
Phase 2 - plateau phase R-HSA-5576893 5.633603e-01 0.249 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 5.633603e-01 0.249 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.633603e-01 0.249 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 5.633603e-01 0.249 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 5.637688e-01 0.249 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 5.645857e-01 0.248 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 5.645857e-01 0.248 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 5.645857e-01 0.248 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.645857e-01 0.248 0 0
FLT3 Signaling R-HSA-9607240 5.645857e-01 0.248 0 0
Muscle contraction R-HSA-397014 5.648395e-01 0.248 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 5.667568e-01 0.247 0 0
DNA Double Strand Break Response R-HSA-5693606 5.677342e-01 0.246 0 0
Signaling by Insulin receptor R-HSA-74752 5.714923e-01 0.243 0 0
Protein folding R-HSA-391251 5.714923e-01 0.243 0 0
Eukaryotic Translation Elongation R-HSA-156842 5.714923e-01 0.243 0 0
Signaling by NOTCH R-HSA-157118 5.745080e-01 0.241 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 5.753807e-01 0.240 0 0
Interferon alpha/beta signaling R-HSA-909733 5.753807e-01 0.240 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 5.757429e-01 0.240 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 5.757429e-01 0.240 0 0
Selenoamino acid metabolism R-HSA-2408522 5.772751e-01 0.239 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 5.802657e-01 0.236 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 5.802657e-01 0.236 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 5.802657e-01 0.236 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 5.802657e-01 0.236 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 5.802657e-01 0.236 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 5.802657e-01 0.236 0 0
Toll-like Receptor Cascades R-HSA-168898 5.866665e-01 0.232 0 0
Activation of GABAB receptors R-HSA-991365 5.866899e-01 0.232 0 0
GABA B receptor activation R-HSA-977444 5.866899e-01 0.232 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 5.866899e-01 0.232 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 5.866899e-01 0.232 0 0
MTOR signalling R-HSA-165159 5.866899e-01 0.232 0 0
Ca-dependent events R-HSA-111996 5.866899e-01 0.232 0 0
SARS-CoV Infections R-HSA-9679506 5.901990e-01 0.229 0 0
Macroautophagy R-HSA-1632852 5.915359e-01 0.228 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.941516e-01 0.226 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 5.941950e-01 0.226 0 0
Epigenetic regulation of gene expression R-HSA-212165 5.950840e-01 0.225 0 0
Homology Directed Repair R-HSA-5693538 5.955853e-01 0.225 0 0
Cytokine Signaling in Immune system R-HSA-1280215 5.961821e-01 0.225 0 0
Chaperone Mediated Autophagy R-HSA-9613829 5.965175e-01 0.224 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 5.965175e-01 0.224 0 0
PKA activation in glucagon signalling R-HSA-164378 5.965175e-01 0.224 0 0
Mismatch Repair R-HSA-5358508 5.965175e-01 0.224 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 5.965175e-01 0.224 0 0
FGFR1 ligand binding and activation R-HSA-190242 5.965175e-01 0.224 0 0
PKA activation R-HSA-163615 5.965175e-01 0.224 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 5.965175e-01 0.224 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 5.965175e-01 0.224 0 0
Platelet sensitization by LDL R-HSA-432142 5.965175e-01 0.224 0 0
Tie2 Signaling R-HSA-210993 5.965175e-01 0.224 0 0
Polo-like kinase mediated events R-HSA-156711 5.965175e-01 0.224 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 5.974262e-01 0.224 0 0
Eukaryotic Translation Termination R-HSA-72764 6.016023e-01 0.221 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.016023e-01 0.221 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 6.022000e-01 0.220 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 6.022000e-01 0.220 0 0
Regulation of mitotic cell cycle R-HSA-453276 6.027212e-01 0.220 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 6.027212e-01 0.220 0 0
DAP12 interactions R-HSA-2172127 6.079518e-01 0.216 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.121410e-01 0.213 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 6.121410e-01 0.213 0 0
Regulation of signaling by CBL R-HSA-912631 6.121410e-01 0.213 0 0
Specification of the neural plate border R-HSA-9834899 6.121410e-01 0.213 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.121410e-01 0.213 0 0
Translesion Synthesis by POLH R-HSA-110320 6.121410e-01 0.213 0 0
The NLRP3 inflammasome R-HSA-844456 6.121410e-01 0.213 0 0
Maturation of nucleoprotein R-HSA-9694631 6.121410e-01 0.213 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 6.121410e-01 0.213 0 0
Other interleukin signaling R-HSA-449836 6.121410e-01 0.213 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.121410e-01 0.213 0 0
Chromosome Maintenance R-HSA-73886 6.152435e-01 0.211 0 0
Telomere Maintenance R-HSA-157579 6.161697e-01 0.210 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 6.161697e-01 0.210 0 0
Nucleosome assembly R-HSA-774815 6.182669e-01 0.209 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 6.182669e-01 0.209 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 6.182669e-01 0.209 0 0
DAG and IP3 signaling R-HSA-1489509 6.182669e-01 0.209 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 6.194987e-01 0.208 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 6.216705e-01 0.206 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 6.216705e-01 0.206 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.271605e-01 0.203 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.271605e-01 0.203 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.271605e-01 0.203 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.271605e-01 0.203 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.271605e-01 0.203 0 0
Co-inhibition by CTLA4 R-HSA-389513 6.271605e-01 0.203 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.271605e-01 0.203 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.271605e-01 0.203 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.271605e-01 0.203 0 0
Signal transduction by L1 R-HSA-445144 6.271605e-01 0.203 0 0
Nephrin family interactions R-HSA-373753 6.271605e-01 0.203 0 0
G2/M DNA damage checkpoint R-HSA-69473 6.277049e-01 0.202 0 0
Signaling by NOTCH4 R-HSA-9013694 6.277049e-01 0.202 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 6.283719e-01 0.202 0 0
Diseases of DNA repair R-HSA-9675135 6.283719e-01 0.202 0 0
Regulation of TNFR1 signaling R-HSA-5357905 6.283719e-01 0.202 0 0
HATs acetylate histones R-HSA-3214847 6.304010e-01 0.200 0 0
Protein ubiquitination R-HSA-8852135 6.357885e-01 0.197 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 6.382678e-01 0.195 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.415992e-01 0.193 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.415992e-01 0.193 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 6.415992e-01 0.193 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.415992e-01 0.193 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 6.415992e-01 0.193 0 0
Lagging Strand Synthesis R-HSA-69186 6.415992e-01 0.193 0 0
Early Phase of HIV Life Cycle R-HSA-162594 6.415992e-01 0.193 0 0
SARS-CoV-1 Infection R-HSA-9678108 6.433836e-01 0.192 0 0
Selenocysteine synthesis R-HSA-2408557 6.442899e-01 0.191 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 6.467290e-01 0.189 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 6.467290e-01 0.189 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 6.467290e-01 0.189 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 6.479554e-01 0.188 0 0
Gluconeogenesis R-HSA-70263 6.479554e-01 0.188 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 6.485406e-01 0.188 0 0
Potential therapeutics for SARS R-HSA-9679191 6.500476e-01 0.187 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 6.554796e-01 0.183 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 6.554796e-01 0.183 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 6.554796e-01 0.183 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 6.554796e-01 0.183 0 0
Ribavirin ADME R-HSA-9755088 6.554796e-01 0.183 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 6.574362e-01 0.182 0 0
DNA Damage Bypass R-HSA-73893 6.574362e-01 0.182 0 0
Viral mRNA Translation R-HSA-192823 6.578312e-01 0.182 0 0
Platelet degranulation R-HSA-114608 6.588599e-01 0.181 0 0
G2/M Checkpoints R-HSA-69481 6.588599e-01 0.181 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 6.611170e-01 0.180 0 0
Interleukin-1 family signaling R-HSA-446652 6.611170e-01 0.180 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 6.644702e-01 0.178 0 0
DNA Double-Strand Break Repair R-HSA-5693532 6.665692e-01 0.176 0 0
PI3K Cascade R-HSA-109704 6.667116e-01 0.176 0 0
Azathioprine ADME R-HSA-9748787 6.667116e-01 0.176 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 6.688233e-01 0.175 0 0
Signaling by KIT in disease R-HSA-9669938 6.688233e-01 0.175 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 6.688233e-01 0.175 0 0
LDL clearance R-HSA-8964038 6.688233e-01 0.175 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 6.688233e-01 0.175 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.688233e-01 0.175 0 0
Activation of HOX genes during differentiation R-HSA-5619507 6.710210e-01 0.173 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 6.710210e-01 0.173 0 0
RSV-host interactions R-HSA-9833110 6.710210e-01 0.173 0 0
PKR-mediated signaling R-HSA-9833482 6.743530e-01 0.171 0 0
Signaling by MET R-HSA-6806834 6.743530e-01 0.171 0 0
Meiotic recombination R-HSA-912446 6.757832e-01 0.170 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.757832e-01 0.170 0 0
PPARA activates gene expression R-HSA-1989781 6.773065e-01 0.169 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 6.774833e-01 0.169 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 6.816509e-01 0.166 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.816509e-01 0.166 0 0
Syndecan interactions R-HSA-3000170 6.816509e-01 0.166 0 0
Processing of DNA double-strand break ends R-HSA-5693607 6.816942e-01 0.166 0 0
G alpha (q) signalling events R-HSA-416476 6.827532e-01 0.166 0 0
Immune System R-HSA-168256 6.834312e-01 0.165 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 6.846530e-01 0.165 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 6.846530e-01 0.165 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 6.878190e-01 0.163 0 0
HCMV Late Events R-HSA-9610379 6.878190e-01 0.163 0 0
HIV Life Cycle R-HSA-162587 6.878190e-01 0.163 0 0
Cardiac conduction R-HSA-5576891 6.879944e-01 0.162 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 6.901415e-01 0.161 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 6.929902e-01 0.159 0 0
Cellular response to starvation R-HSA-9711097 6.929902e-01 0.159 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 6.933229e-01 0.159 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 6.933229e-01 0.159 0 0
Amino acids regulate mTORC1 R-HSA-9639288 6.933229e-01 0.159 0 0
Degradation of the extracellular matrix R-HSA-1474228 6.936142e-01 0.159 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 6.939824e-01 0.159 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 6.939824e-01 0.159 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 6.939824e-01 0.159 0 0
Plasma lipoprotein assembly R-HSA-8963898 6.939824e-01 0.159 0 0
SARS-CoV-2 Infection R-HSA-9694516 6.962071e-01 0.157 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 6.963370e-01 0.157 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 6.963370e-01 0.157 0 0
Antigen processing-Cross presentation R-HSA-1236975 6.963370e-01 0.157 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 6.991644e-01 0.155 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 6.994504e-01 0.155 0 0
Regulation of TP53 Activity R-HSA-5633007 7.031615e-01 0.153 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 7.058370e-01 0.151 0 0
G protein gated Potassium channels R-HSA-1296059 7.058370e-01 0.151 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.058370e-01 0.151 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.058370e-01 0.151 0 0
Formation of the nephric duct R-HSA-9830364 7.058370e-01 0.151 0 0
Laminin interactions R-HSA-3000157 7.058370e-01 0.151 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.084611e-01 0.150 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.084611e-01 0.150 0 0
Meiosis R-HSA-1500620 7.098256e-01 0.149 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 7.098256e-01 0.149 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 7.100720e-01 0.149 0 0
G alpha (z) signalling events R-HSA-418597 7.100720e-01 0.149 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.165523e-01 0.145 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 7.172330e-01 0.144 0 0
MET activates PTK2 signaling R-HSA-8874081 7.172330e-01 0.144 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 7.172330e-01 0.144 0 0
Metalloprotease DUBs R-HSA-5689901 7.172330e-01 0.144 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 7.172330e-01 0.144 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.172330e-01 0.144 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 7.172330e-01 0.144 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 7.181559e-01 0.144 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.181559e-01 0.144 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.202293e-01 0.143 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.202293e-01 0.143 0 0
Inositol phosphate metabolism R-HSA-1483249 7.202293e-01 0.143 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.229268e-01 0.141 0 0
IRS-mediated signalling R-HSA-112399 7.260494e-01 0.139 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 7.260494e-01 0.139 0 0
Synthesis of PA R-HSA-1483166 7.260494e-01 0.139 0 0
Packaging Of Telomere Ends R-HSA-171306 7.281882e-01 0.138 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 7.281882e-01 0.138 0 0
Signaling by BMP R-HSA-201451 7.281882e-01 0.138 0 0
Triglyceride biosynthesis R-HSA-75109 7.281882e-01 0.138 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.281882e-01 0.138 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.281882e-01 0.138 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 7.281882e-01 0.138 0 0
Insulin processing R-HSA-264876 7.281882e-01 0.138 0 0
Ribosome-associated quality control R-HSA-9948299 7.309990e-01 0.136 0 0
SLC transporter disorders R-HSA-5619102 7.369488e-01 0.133 0 0
HCMV Infection R-HSA-9609646 7.373469e-01 0.132 0 0
Telomere Extension By Telomerase R-HSA-171319 7.387197e-01 0.132 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.387197e-01 0.132 0 0
Insulin receptor recycling R-HSA-77387 7.387197e-01 0.132 0 0
Inflammasomes R-HSA-622312 7.387197e-01 0.132 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 7.387197e-01 0.132 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 7.387197e-01 0.132 0 0
Peroxisomal protein import R-HSA-9033241 7.412756e-01 0.130 0 0
Extension of Telomeres R-HSA-180786 7.412756e-01 0.130 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 7.412756e-01 0.130 0 0
Regulation of beta-cell development R-HSA-186712 7.412756e-01 0.130 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 7.412756e-01 0.130 0 0
ER-Phagosome pathway R-HSA-1236974 7.422532e-01 0.129 0 0
HCMV Early Events R-HSA-9609690 7.432813e-01 0.129 0 0
Innate Immune System R-HSA-168249 7.477024e-01 0.126 0 0
Base Excision Repair R-HSA-73884 7.483811e-01 0.126 0 0
GABA receptor activation R-HSA-977443 7.486137e-01 0.126 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 7.486137e-01 0.126 0 0
DNA methylation R-HSA-5334118 7.488437e-01 0.126 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.488437e-01 0.126 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 7.488437e-01 0.126 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.488437e-01 0.126 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 7.488437e-01 0.126 0 0
Regulation of gene expression in beta cells R-HSA-210745 7.488437e-01 0.126 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 7.520246e-01 0.124 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.534159e-01 0.123 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.534159e-01 0.123 0 0
Late Phase of HIV Life Cycle R-HSA-162599 7.556098e-01 0.122 0 0
Formation of paraxial mesoderm R-HSA-9793380 7.557723e-01 0.122 0 0
MAP kinase activation R-HSA-450294 7.557723e-01 0.122 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.557723e-01 0.122 0 0
Nucleotide salvage R-HSA-8956321 7.557723e-01 0.122 0 0
PLC beta mediated events R-HSA-112043 7.557723e-01 0.122 0 0
Activation of the pre-replicative complex R-HSA-68962 7.585760e-01 0.120 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 7.585760e-01 0.120 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.585760e-01 0.120 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.585760e-01 0.120 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.585760e-01 0.120 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 7.585760e-01 0.120 0 0
Rab regulation of trafficking R-HSA-9007101 7.586417e-01 0.120 0 0
Co-inhibition by PD-1 R-HSA-389948 7.598704e-01 0.119 0 0
NCAM signaling for neurite out-growth R-HSA-375165 7.627543e-01 0.118 0 0
Signaling by PDGF R-HSA-186797 7.627543e-01 0.118 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 7.627543e-01 0.118 0 0
Heme signaling R-HSA-9707616 7.627543e-01 0.118 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 7.627543e-01 0.118 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 7.636600e-01 0.117 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.679317e-01 0.115 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 7.688356e-01 0.114 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 7.695626e-01 0.114 0 0
FCGR activation R-HSA-2029481 7.717327e-01 0.113 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 7.717327e-01 0.113 0 0
Signaling by ROBO receptors R-HSA-376176 7.717960e-01 0.112 0 0
G0 and Early G1 R-HSA-1538133 7.769255e-01 0.110 0 0
Signaling by WNT in cancer R-HSA-4791275 7.769255e-01 0.110 0 0
HS-GAG degradation R-HSA-2024096 7.769255e-01 0.110 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 7.769255e-01 0.110 0 0
DNA strand elongation R-HSA-69190 7.769255e-01 0.110 0 0
Hemostasis R-HSA-109582 7.769662e-01 0.110 0 0
Cellular response to hypoxia R-HSA-1234174 7.826699e-01 0.106 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 7.855712e-01 0.105 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 7.855712e-01 0.105 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.855712e-01 0.105 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 7.855712e-01 0.105 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 7.855712e-01 0.105 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 7.855712e-01 0.105 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.855712e-01 0.105 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 7.855712e-01 0.105 0 0
Gastrulation R-HSA-9758941 7.871802e-01 0.104 0 0
MITF-M-dependent gene expression R-HSA-9856651 7.914209e-01 0.102 0 0
Host Interactions of HIV factors R-HSA-162909 7.928443e-01 0.101 0 0
Striated Muscle Contraction R-HSA-390522 7.938824e-01 0.100 0 0
Resolution of D-Loop Structures R-HSA-5693537 7.938824e-01 0.100 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 7.938824e-01 0.100 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 7.938824e-01 0.100 0 0
Acyl chain remodelling of PC R-HSA-1482788 7.938824e-01 0.100 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 7.938824e-01 0.100 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.938824e-01 0.100 0 0
G-protein mediated events R-HSA-112040 7.951184e-01 0.100 0 0
Cellular response to chemical stress R-HSA-9711123 8.005979e-01 0.097 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 8.011032e-01 0.096 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.018718e-01 0.096 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 8.018718e-01 0.096 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.018718e-01 0.096 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 8.018718e-01 0.096 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.018718e-01 0.096 0 0
Signal amplification R-HSA-392518 8.018718e-01 0.096 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 8.018718e-01 0.096 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 8.018718e-01 0.096 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 8.034069e-01 0.095 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 8.034069e-01 0.095 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 8.034069e-01 0.095 0 0
DNA Replication R-HSA-69306 8.037478e-01 0.095 0 0
Interferon Signaling R-HSA-913531 8.056448e-01 0.094 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 8.062636e-01 0.094 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.095521e-01 0.092 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.095521e-01 0.092 0 0
PERK regulates gene expression R-HSA-381042 8.095521e-01 0.092 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 8.126091e-01 0.090 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 8.126091e-01 0.090 0 0
Interleukin-17 signaling R-HSA-448424 8.126091e-01 0.090 0 0
Hedgehog 'off' state R-HSA-5610787 8.131116e-01 0.090 0 0
HSF1 activation R-HSA-3371511 8.169351e-01 0.088 0 0
FLT3 signaling in disease R-HSA-9682385 8.169351e-01 0.088 0 0
G1/S-Specific Transcription R-HSA-69205 8.169351e-01 0.088 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.169351e-01 0.088 0 0
Hedgehog 'on' state R-HSA-5632684 8.181363e-01 0.087 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 8.224078e-01 0.085 0 0
PI Metabolism R-HSA-1483255 8.224078e-01 0.085 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 8.235172e-01 0.084 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 8.235172e-01 0.084 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 8.240324e-01 0.084 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 8.240324e-01 0.084 0 0
Degradation of DVL R-HSA-4641258 8.240324e-01 0.084 0 0
Cleavage of the damaged purine R-HSA-110331 8.240324e-01 0.084 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 8.240324e-01 0.084 0 0
Collagen chain trimerization R-HSA-8948216 8.240324e-01 0.084 0 0
Interferon gamma signaling R-HSA-877300 8.266665e-01 0.083 0 0
Ca2+ pathway R-HSA-4086398 8.287547e-01 0.082 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 8.308549e-01 0.080 0 0
Depurination R-HSA-73927 8.308549e-01 0.080 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.308549e-01 0.080 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 8.308549e-01 0.080 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 8.313069e-01 0.080 0 0
Cilium Assembly R-HSA-5617833 8.316742e-01 0.080 0 0
Neddylation R-HSA-8951664 8.373307e-01 0.077 0 0
Plasma lipoprotein clearance R-HSA-8964043 8.374132e-01 0.077 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.374132e-01 0.077 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 8.374132e-01 0.077 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 8.381605e-01 0.077 0 0
UCH proteinases R-HSA-5689603 8.436371e-01 0.074 0 0
Aggrephagy R-HSA-9646399 8.437177e-01 0.074 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 8.437177e-01 0.074 0 0
Translation of Structural Proteins R-HSA-9694635 8.483311e-01 0.071 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.497781e-01 0.071 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 8.497781e-01 0.071 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 8.497781e-01 0.071 0 0
Maturation of spike protein R-HSA-9694548 8.497781e-01 0.071 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 8.497781e-01 0.071 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 8.518945e-01 0.070 0 0
Nuclear Receptor transcription pathway R-HSA-383280 8.528966e-01 0.069 0 0
Integrin cell surface interactions R-HSA-216083 8.528966e-01 0.069 0 0
HIV Infection R-HSA-162906 8.546141e-01 0.068 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 8.556038e-01 0.068 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.556038e-01 0.068 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.556038e-01 0.068 0 0
Translation of Structural Proteins R-HSA-9683701 8.556038e-01 0.068 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 8.557392e-01 0.068 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 8.573366e-01 0.067 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 8.573366e-01 0.067 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.612040e-01 0.065 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.612040e-01 0.065 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 8.612040e-01 0.065 0 0
Depyrimidination R-HSA-73928 8.612040e-01 0.065 0 0
Amyloid fiber formation R-HSA-977225 8.658512e-01 0.063 0 0
tRNA processing R-HSA-72306 8.659856e-01 0.062 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.667544e-01 0.062 0 0
G alpha (s) signalling events R-HSA-418555 8.688951e-01 0.061 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 8.699315e-01 0.061 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 8.702581e-01 0.060 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 8.717620e-01 0.060 0 0
Surfactant metabolism R-HSA-5683826 8.717620e-01 0.060 0 0
Methylation R-HSA-156581 8.717620e-01 0.060 0 0
Amine ligand-binding receptors R-HSA-375280 8.717620e-01 0.060 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 8.736803e-01 0.059 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 8.767364e-01 0.057 0 0
Fanconi Anemia Pathway R-HSA-6783310 8.767364e-01 0.057 0 0
Somitogenesis R-HSA-9824272 8.767364e-01 0.057 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 8.767364e-01 0.057 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.767364e-01 0.057 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 8.767364e-01 0.057 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 8.767364e-01 0.057 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 8.777518e-01 0.057 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 8.802857e-01 0.055 0 0
Keratinization R-HSA-6805567 8.805998e-01 0.055 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.815181e-01 0.055 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.815181e-01 0.055 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 8.815181e-01 0.055 0 0
DNA Repair R-HSA-73894 8.836871e-01 0.054 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.861146e-01 0.053 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 8.861146e-01 0.053 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 8.861146e-01 0.053 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 8.871069e-01 0.052 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 8.886719e-01 0.051 0 0
Peptide hormone metabolism R-HSA-2980736 8.896185e-01 0.051 0 0
ER to Golgi Anterograde Transport R-HSA-199977 8.898350e-01 0.051 0 0
Intraflagellar transport R-HSA-5620924 8.905331e-01 0.050 0 0
NGF-stimulated transcription R-HSA-9031628 8.905331e-01 0.050 0 0
Metal ion SLC transporters R-HSA-425410 8.905331e-01 0.050 0 0
S Phase R-HSA-69242 8.925053e-01 0.049 0 0
Gap junction trafficking and regulation R-HSA-157858 8.947804e-01 0.048 0 0
Regulation of RAS by GAPs R-HSA-5658442 8.988631e-01 0.046 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.010482e-01 0.045 0 0
Downstream TCR signaling R-HSA-202424 9.018277e-01 0.045 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.026273e-01 0.044 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.027877e-01 0.044 0 0
The phototransduction cascade R-HSA-2514856 9.027877e-01 0.044 0 0
Orc1 removal from chromatin R-HSA-68949 9.065602e-01 0.043 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.065602e-01 0.043 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.065602e-01 0.043 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.101865e-01 0.041 0 0
Nucleotide biosynthesis R-HSA-8956320 9.101865e-01 0.041 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.107272e-01 0.041 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.107272e-01 0.041 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.136723e-01 0.039 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.136723e-01 0.039 0 0
G1/S Transition R-HSA-69206 9.138299e-01 0.039 0 0
Collagen formation R-HSA-1474290 9.162343e-01 0.038 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 9.170230e-01 0.038 0 0
Paracetamol ADME R-HSA-9753281 9.170230e-01 0.038 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 9.202439e-01 0.036 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 9.202439e-01 0.036 0 0
Ion homeostasis R-HSA-5578775 9.202439e-01 0.036 0 0
Dectin-2 family R-HSA-5621480 9.233399e-01 0.035 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.238999e-01 0.034 0 0
COPI-mediated anterograde transport R-HSA-6807878 9.238999e-01 0.034 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.263159e-01 0.033 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.263159e-01 0.033 0 0
Reproduction R-HSA-1474165 9.271772e-01 0.033 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.291766e-01 0.032 0 0
Triglyceride metabolism R-HSA-8979227 9.291766e-01 0.032 0 0
Phospholipid metabolism R-HSA-1483257 9.293010e-01 0.032 0 0
Disease R-HSA-1643685 9.296414e-01 0.032 0 0
Circadian clock R-HSA-9909396 9.311869e-01 0.031 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 9.319264e-01 0.031 0 0
Glutathione conjugation R-HSA-156590 9.319264e-01 0.031 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.319264e-01 0.031 0 0
Signaling by WNT R-HSA-195721 9.334671e-01 0.030 0 0
Aquaporin-mediated transport R-HSA-445717 9.345696e-01 0.029 0 0
Interleukin-1 signaling R-HSA-9020702 9.352254e-01 0.029 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 9.371103e-01 0.028 0 0
Mitochondrial protein import R-HSA-1268020 9.371103e-01 0.028 0 0
Regulation of endogenous retroelements R-HSA-9842860 9.372903e-01 0.028 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.374244e-01 0.028 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.374244e-01 0.028 0 0
Opioid Signalling R-HSA-111885 9.412342e-01 0.026 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.419000e-01 0.026 0 0
Signaling by Hedgehog R-HSA-5358351 9.436737e-01 0.025 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.445825e-01 0.025 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.445825e-01 0.025 0 0
Nucleotide Excision Repair R-HSA-5696398 9.449419e-01 0.025 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.463254e-01 0.024 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 9.484102e-01 0.023 0 0
Kidney development R-HSA-9830369 9.484102e-01 0.023 0 0
Nicotinate metabolism R-HSA-196807 9.484102e-01 0.023 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.484102e-01 0.023 0 0
Synthesis of DNA R-HSA-69239 9.484263e-01 0.023 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.504142e-01 0.022 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.516999e-01 0.021 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.517777e-01 0.021 0 0
TCR signaling R-HSA-202403 9.532614e-01 0.021 0 0
COPII-mediated vesicle transport R-HSA-204005 9.541921e-01 0.020 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 9.541921e-01 0.020 0 0
Viral Infection Pathways R-HSA-9824446 9.559624e-01 0.020 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.559718e-01 0.020 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.559718e-01 0.020 0 0
TCF dependent signaling in response to WNT R-HSA-201681 9.575343e-01 0.019 0 0
Purine catabolism R-HSA-74259 9.576825e-01 0.019 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.576825e-01 0.019 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 9.576825e-01 0.019 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 9.576825e-01 0.019 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.593268e-01 0.018 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.609073e-01 0.017 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 9.624265e-01 0.017 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.624265e-01 0.017 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.624265e-01 0.017 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.629154e-01 0.016 0 0
Protein localization R-HSA-9609507 9.647424e-01 0.016 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.652904e-01 0.015 0 0
Extracellular matrix organization R-HSA-1474244 9.669051e-01 0.015 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.696394e-01 0.013 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 9.697984e-01 0.013 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.703807e-01 0.013 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.726391e-01 0.012 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.726391e-01 0.012 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.737030e-01 0.012 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.747743e-01 0.011 0 0
Infectious disease R-HSA-5663205 9.764119e-01 0.010 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.766531e-01 0.010 0 0
Pyruvate metabolism R-HSA-70268 9.775611e-01 0.010 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.784339e-01 0.009 0 0
Neurotransmitter release cycle R-HSA-112310 9.800790e-01 0.009 0 0
Organelle biogenesis and maintenance R-HSA-1852241 9.805937e-01 0.009 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.830029e-01 0.007 0 0
Integration of energy metabolism R-HSA-163685 9.834825e-01 0.007 0 0
Regulation of insulin secretion R-HSA-422356 9.866051e-01 0.006 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.871265e-01 0.006 0 0
ABC-family proteins mediated transport R-HSA-382556 9.876276e-01 0.005 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.878686e-01 0.005 0 0
Platelet homeostasis R-HSA-418346 9.906306e-01 0.004 0 0
Metabolism of nucleotides R-HSA-15869 9.907551e-01 0.004 0 0
Gene expression (Transcription) R-HSA-74160 9.908790e-01 0.004 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.910232e-01 0.004 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.920073e-01 0.003 0 0
RNA Polymerase II Transcription R-HSA-73857 9.922078e-01 0.003 0 0
Antimicrobial peptides R-HSA-6803157 9.923186e-01 0.003 0 0
Generic Transcription Pathway R-HSA-212436 9.925870e-01 0.003 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.937030e-01 0.003 0 0
Mitochondrial biogenesis R-HSA-1592230 9.944109e-01 0.002 0 0
G alpha (i) signalling events R-HSA-418594 9.946051e-01 0.002 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.955972e-01 0.002 0 0
Drug ADME R-HSA-9748784 9.956300e-01 0.002 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.959653e-01 0.002 0 0
Nucleotide catabolism R-HSA-8956319 9.966673e-01 0.001 0 0
Bacterial Infection Pathways R-HSA-9824439 9.967965e-01 0.001 0 0
GPCR downstream signalling R-HSA-388396 9.968139e-01 0.001 0 0
Translation R-HSA-72766 9.969123e-01 0.001 0 0
Sensory perception of taste R-HSA-9717189 9.970424e-01 0.001 0 0
Diseases of glycosylation R-HSA-3781865 9.971110e-01 0.001 0 0
Peptide ligand-binding receptors R-HSA-375276 9.973091e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.975020e-01 0.001 0 0
Post-translational protein modification R-HSA-597592 9.975976e-01 0.001 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.979028e-01 0.001 0 0
Visual phototransduction R-HSA-2187338 9.985557e-01 0.001 0 0
Signaling by GPCR R-HSA-372790 9.988587e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.991216e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.993873e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.994668e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.997333e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.998392e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999496e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.999662e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999769e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.999827e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999929e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999961e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999964e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999970e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999978e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999994e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.110223e-16 15.955 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.110223e-16 15.955 0 0
PKR-mediated signaling R-HSA-9833482 1.110223e-16 15.955 0 0
HSF1 activation R-HSA-3371511 1.110223e-16 15.955 0 0
Attenuation phase R-HSA-3371568 1.110223e-16 15.955 0 0
HSF1-dependent transactivation R-HSA-3371571 1.110223e-16 15.955 0 0
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.110223e-16 15.955 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.110223e-16 15.955 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 1 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 1 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.220446e-16 15.654 0 0
Interferon Signaling R-HSA-913531 1.110223e-15 14.955 0 0
Aggrephagy R-HSA-9646399 6.550316e-15 14.184 0 0
Cell Cycle, Mitotic R-HSA-69278 3.785861e-14 13.422 0 0
Cell Cycle R-HSA-1640170 4.196643e-14 13.377 0 0
Eukaryotic Translation Elongation R-HSA-156842 8.382184e-14 13.077 0 0
Cap-dependent Translation Initiation R-HSA-72737 8.326673e-14 13.080 0 0
Eukaryotic Translation Initiation R-HSA-72613 8.326673e-14 13.080 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 1.205702e-13 12.919 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 3.845813e-13 12.415 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 4.938272e-13 12.306 0 0
Cytokine Signaling in Immune system R-HSA-1280215 5.202505e-13 12.284 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.964118e-13 12.224 0 0
Transport of connexons to the plasma membrane R-HSA-190872 6.921130e-13 12.160 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.130207e-12 11.947 0 0
Post NMDA receptor activation events R-HSA-438064 1.130207e-12 11.947 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.635247e-12 11.786 0 0
Metabolism of RNA R-HSA-8953854 1.789791e-12 11.747 0 0
SARS-CoV-1 Infection R-HSA-9678108 2.418399e-12 11.616 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 3.047229e-12 11.516 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 3.207434e-12 11.494 0 0
Protein folding R-HSA-391251 3.922862e-12 11.406 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 7.079781e-12 11.150 0 0
Apoptosis R-HSA-109581 8.285927e-12 11.082 0 0
Formation of a pool of free 40S subunits R-HSA-72689 8.581802e-12 11.066 0 0
Peptide chain elongation R-HSA-156902 9.459877e-12 11.024 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 9.455103e-12 11.024 0 0
Selective autophagy R-HSA-9663891 9.459877e-12 11.024 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 9.852563e-12 11.006 0 0
Viral Infection Pathways R-HSA-9824446 1.629219e-11 10.788 0 0
Influenza Infection R-HSA-168255 1.896228e-11 10.722 0 0
Programmed Cell Death R-HSA-5357801 2.597511e-11 10.585 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 3.129241e-11 10.505 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.114897e-11 10.507 0 0
Developmental Biology R-HSA-1266738 3.520007e-11 10.453 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.122236e-11 10.213 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 6.224365e-11 10.206 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 6.909628e-11 10.161 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 8.734979e-11 10.059 0 0
Mitotic Anaphase R-HSA-68882 8.945222e-11 10.048 0 0
Recycling pathway of L1 R-HSA-437239 9.410950e-11 10.026 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 9.971801e-11 10.001 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 1.077146e-10 9.968 0 0
Ribosome-associated quality control R-HSA-9948299 1.448214e-10 9.839 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.923708e-10 9.716 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 1.968229e-10 9.706 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 1.968229e-10 9.706 0 0
G2/M Transition R-HSA-69275 1.940275e-10 9.712 0 0
Cell junction organization R-HSA-446728 2.135242e-10 9.671 0 0
Mitotic G2-G2/M phases R-HSA-453274 2.443766e-10 9.612 0 0
Eukaryotic Translation Termination R-HSA-72764 3.145584e-10 9.502 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.363183e-10 9.473 0 0
Gap junction trafficking R-HSA-190828 3.564523e-10 9.448 0 0
Mitotic Prometaphase R-HSA-68877 4.296390e-10 9.367 0 0
Cell-Cell communication R-HSA-1500931 5.052153e-10 9.297 0 0
Translation initiation complex formation R-HSA-72649 5.652543e-10 9.248 0 0
Selenocysteine synthesis R-HSA-2408557 8.560209e-10 9.068 0 0
Mitotic Prophase R-HSA-68875 8.915287e-10 9.050 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.035724e-09 8.985 0 0
Viral mRNA Translation R-HSA-192823 1.178069e-09 8.929 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.214829e-09 8.915 0 0
Gap junction assembly R-HSA-190861 1.214829e-09 8.915 0 0
Gap junction trafficking and regulation R-HSA-157858 1.301637e-09 8.886 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.378495e-09 8.861 0 0
HCMV Early Events R-HSA-9609690 2.374190e-09 8.624 0 0
L1CAM interactions R-HSA-373760 2.502364e-09 8.602 0 0
Separation of Sister Chromatids R-HSA-2467813 4.286208e-09 8.368 0 0
SARS-CoV-2-host interactions R-HSA-9705683 4.407634e-09 8.356 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 5.003074e-09 8.301 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 5.339527e-09 8.272 1 1
Ribosomal scanning and start codon recognition R-HSA-72702 6.513179e-09 8.186 0 0
Autophagy R-HSA-9612973 7.180677e-09 8.144 0 0
Cellular Senescence R-HSA-2559583 6.804392e-09 8.167 1 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.697588e-08 7.770 0 0
Signaling by ROBO receptors R-HSA-376176 1.805675e-08 7.743 0 0
Macroautophagy R-HSA-1632852 2.004194e-08 7.698 0 0
Glycolysis R-HSA-70171 2.030272e-08 7.692 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.386671e-08 7.622 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.792819e-08 7.554 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 3.049203e-08 7.516 0 0
HCMV Infection R-HSA-9609646 3.088105e-08 7.510 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.641809e-08 7.439 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 3.665178e-08 7.436 0 0
Apoptotic execution phase R-HSA-75153 3.665178e-08 7.436 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 3.912375e-08 7.408 0 0
Infectious disease R-HSA-5663205 3.943495e-08 7.404 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 4.560749e-08 7.341 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 4.578016e-08 7.339 0 0
Interleukin-12 signaling R-HSA-9020591 4.591397e-08 7.338 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 4.936690e-08 7.307 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 4.936690e-08 7.307 0 0
Folding of actin by CCT/TriC R-HSA-390450 5.526423e-08 7.258 0 0
Interleukin-12 family signaling R-HSA-447115 5.743045e-08 7.241 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 5.757614e-08 7.240 0 0
Cilium Assembly R-HSA-5617833 6.958438e-08 7.157 0 0
mRNA Splicing R-HSA-72172 7.773998e-08 7.109 0 0
Signaling by ERBB2 R-HSA-1227986 9.538702e-08 7.021 0 0
Kinesins R-HSA-983189 9.538702e-08 7.021 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.210498e-07 6.917 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.643171e-07 6.784 0 0
Signaling by PTK6 R-HSA-8848021 1.643171e-07 6.784 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 2.325843e-07 6.633 0 0
Signaling by RAS mutants R-HSA-6802949 2.569984e-07 6.590 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.569984e-07 6.590 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.569984e-07 6.590 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.569984e-07 6.590 0 0
Selenoamino acid metabolism R-HSA-2408522 2.574521e-07 6.589 0 0
Glucose metabolism R-HSA-70326 2.775348e-07 6.557 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.015572e-07 6.521 0 0
Regulation of CDH1 Function R-HSA-9764561 3.362594e-07 6.473 0 0
Diseases of programmed cell death R-HSA-9645723 3.374485e-07 6.472 0 0
Cell-cell junction organization R-HSA-421270 3.445017e-07 6.463 0 0
Chaperone Mediated Autophagy R-HSA-9613829 3.623330e-07 6.441 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 3.630271e-07 6.440 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 4.138130e-07 6.383 0 0
Translation R-HSA-72766 4.330549e-07 6.363 0 0
Hedgehog 'off' state R-HSA-5610787 4.649633e-07 6.333 0 0
Immune System R-HSA-168256 4.920086e-07 6.308 0 0
Signaling by RAF1 mutants R-HSA-9656223 6.185933e-07 6.209 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 8.202603e-07 6.086 0 0
Adherens junctions interactions R-HSA-418990 8.400614e-07 6.076 0 0
Cell-extracellular matrix interactions R-HSA-446353 9.428319e-07 6.026 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 9.877952e-07 6.005 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 9.877952e-07 6.005 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.268507e-06 5.897 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.296568e-06 5.887 0 0
Cellular response to starvation R-HSA-9711097 1.899618e-06 5.721 0 0
rRNA processing R-HSA-72312 2.406401e-06 5.619 0 0
Gluconeogenesis R-HSA-70263 2.418424e-06 5.616 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 2.989126e-06 5.524 0 0
EPH-Ephrin signaling R-HSA-2682334 3.024883e-06 5.519 0 0
Signaling by Hedgehog R-HSA-5358351 3.477029e-06 5.459 0 0
Signal Transduction R-HSA-162582 3.477424e-06 5.459 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 3.672781e-06 5.435 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.672781e-06 5.435 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 4.874776e-06 5.312 0 0
Gene Silencing by RNA R-HSA-211000 5.082614e-06 5.294 0 0
Signaling by EGFR in Cancer R-HSA-1643713 5.237076e-06 5.281 0 0
Metalloprotease DUBs R-HSA-5689901 5.237076e-06 5.281 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 5.691167e-06 5.245 0 0
SARS-CoV Infections R-HSA-9679506 6.627955e-06 5.179 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 6.681197e-06 5.175 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 6.685696e-06 5.175 0 0
Oncogene Induced Senescence R-HSA-2559585 6.737672e-06 5.171 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.803007e-06 5.167 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.139389e-06 5.146 0 0
Hemostasis R-HSA-109582 7.261594e-06 5.139 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 7.782740e-06 5.109 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.632691e-06 5.064 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 8.843215e-06 5.053 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.006560e-05 4.997 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.003011e-05 4.999 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.064229e-05 4.973 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.064963e-05 4.973 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.064963e-05 4.973 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.064963e-05 4.973 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.096679e-05 4.960 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.235430e-05 4.908 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.259175e-05 4.900 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.310179e-05 4.883 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.322670e-05 4.879 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.322670e-05 4.879 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.352207e-05 4.869 0 0
Intraflagellar transport R-HSA-5620924 1.403351e-05 4.853 0 0
Disease R-HSA-1643685 1.661846e-05 4.779 0 0
Co-inhibition by PD-1 R-HSA-389948 1.801930e-05 4.744 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.864864e-05 4.729 0 0
MAPK family signaling cascades R-HSA-5683057 1.886891e-05 4.724 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.934940e-05 4.713 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.979381e-05 4.703 0 0
MAP2K and MAPK activation R-HSA-5674135 2.487266e-05 4.604 0 0
Negative regulation of MAPK pathway R-HSA-5675221 2.487266e-05 4.604 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 2.459562e-05 4.609 0 0
DNA Replication Pre-Initiation R-HSA-69002 2.413984e-05 4.617 0 0
COPI-mediated anterograde transport R-HSA-6807878 2.230444e-05 4.652 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 2.230444e-05 4.652 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.531439e-05 4.597 0 0
Neurodegenerative Diseases R-HSA-8863678 2.531439e-05 4.597 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.531439e-05 4.597 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.544111e-05 4.594 0 0
UCH proteinases R-HSA-5689603 2.872909e-05 4.542 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 2.987738e-05 4.525 0 0
RAF/MAP kinase cascade R-HSA-5673001 3.220519e-05 4.492 0 0
Transmission across Chemical Synapses R-HSA-112315 3.233086e-05 4.490 0 0
Estrogen-dependent gene expression R-HSA-9018519 3.492090e-05 4.457 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 3.560852e-05 4.448 0 0
RMTs methylate histone arginines R-HSA-3214858 4.074165e-05 4.390 0 0
Platelet degranulation R-HSA-114608 4.626027e-05 4.335 0 0
G2/M Checkpoints R-HSA-69481 4.626027e-05 4.335 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.651491e-05 4.332 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.779684e-05 4.321 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 4.915269e-05 4.308 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.915269e-05 4.308 0 0
Amyloid fiber formation R-HSA-977225 5.136396e-05 4.289 0 0
Signaling by WNT R-HSA-195721 5.250161e-05 4.280 0 0
Assembly of the pre-replicative complex R-HSA-68867 5.738857e-05 4.241 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 5.740235e-05 4.241 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 7.479184e-05 4.126 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 7.368368e-05 4.133 0 0
DNA methylation R-HSA-5334118 7.368368e-05 4.133 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 6.869614e-05 4.163 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.135189e-05 4.147 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 7.479184e-05 4.126 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 7.867838e-05 4.104 0 0
Meiosis R-HSA-1500620 7.936703e-05 4.100 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 8.664817e-05 4.062 0 0
Cell Cycle Checkpoints R-HSA-69620 9.445117e-05 4.025 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 9.605712e-05 4.017 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.017993e-04 3.992 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.054098e-04 3.977 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 1.076114e-04 3.968 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.084982e-04 3.965 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.120136e-04 3.951 0 0
Meiotic recombination R-HSA-912446 1.139176e-04 3.943 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.150443e-04 3.939 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.150443e-04 3.939 0 0
Muscle contraction R-HSA-397014 1.175628e-04 3.930 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.181357e-04 3.928 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.355647e-04 3.868 0 0
Josephin domain DUBs R-HSA-5689877 1.620195e-04 3.790 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.639335e-04 3.785 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.802948e-04 3.744 0 0
Signaling by Interleukins R-HSA-449147 1.909894e-04 3.719 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 2.110260e-04 3.676 0 0
Membrane Trafficking R-HSA-199991 2.119902e-04 3.674 0 0
RAF activation R-HSA-5673000 2.145015e-04 3.669 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 2.145015e-04 3.669 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 2.145015e-04 3.669 0 0
Long-term potentiation R-HSA-9620244 2.219049e-04 3.654 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 2.275043e-04 3.643 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 2.275043e-04 3.643 0 0
Neutrophil degranulation R-HSA-6798695 2.369470e-04 3.625 0 0
Maturation of protein E R-HSA-9683683 2.789362e-04 3.554 0 0
Maturation of protein E R-HSA-9694493 2.789362e-04 3.554 0 0
PRC2 methylates histones and DNA R-HSA-212300 2.940394e-04 3.532 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 2.940394e-04 3.532 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.940394e-04 3.532 0 0
FLT3 signaling in disease R-HSA-9682385 2.940394e-04 3.532 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 3.113991e-04 3.507 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 3.113991e-04 3.507 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 3.188791e-04 3.496 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 3.221867e-04 3.492 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.246459e-04 3.489 0 0
MHC class II antigen presentation R-HSA-2132295 3.246459e-04 3.489 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.420100e-04 3.466 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 3.420100e-04 3.466 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.486991e-04 3.458 0 0
Host Interactions of HIV factors R-HSA-162909 3.498865e-04 3.456 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.500750e-04 3.456 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 3.516701e-04 3.454 0 0
Regulation of signaling by CBL R-HSA-912631 3.651507e-04 3.438 0 0
G2/M DNA damage checkpoint R-HSA-69473 3.874205e-04 3.412 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 4.168554e-04 3.380 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.168554e-04 3.380 0 0
p75NTR recruits signalling complexes R-HSA-209543 4.168554e-04 3.380 0 0
Centrosome maturation R-HSA-380287 4.280536e-04 3.369 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 4.358641e-04 3.361 0 0
Late endosomal microautophagy R-HSA-9615710 4.559262e-04 3.341 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 4.559262e-04 3.341 0 0
RAS processing R-HSA-9648002 4.571092e-04 3.340 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 4.571092e-04 3.340 0 0
ESR-mediated signaling R-HSA-8939211 4.685610e-04 3.329 0 0
Semaphorin interactions R-HSA-373755 4.858099e-04 3.314 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 5.228660e-04 3.282 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 5.228660e-04 3.282 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 5.228660e-04 3.282 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 5.228660e-04 3.282 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 5.236262e-04 3.281 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 5.254370e-04 3.279 0 0
Activation of BH3-only proteins R-HSA-114452 5.376534e-04 3.269 0 0
Signaling by NOTCH R-HSA-157118 5.450483e-04 3.264 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 7.060503e-04 3.151 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 6.730020e-04 3.172 0 0
EGFR downregulation R-HSA-182971 6.306264e-04 3.200 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 5.913778e-04 3.228 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 6.018043e-04 3.221 0 0
Meiotic synapsis R-HSA-1221632 6.639246e-04 3.178 0 0
Regulation of PTEN localization R-HSA-8948747 6.414470e-04 3.193 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 7.060503e-04 3.151 0 0
Smooth Muscle Contraction R-HSA-445355 6.639246e-04 3.178 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.099335e-04 3.149 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 8.109842e-04 3.091 0 0
HDACs deacetylate histones R-HSA-3214815 8.308574e-04 3.080 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 8.502560e-04 3.070 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 8.546498e-04 3.068 0 0
Defective pyroptosis R-HSA-9710421 8.861201e-04 3.053 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 8.970250e-04 3.047 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 8.970250e-04 3.047 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 8.970250e-04 3.047 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 8.970250e-04 3.047 0 0
Spry regulation of FGF signaling R-HSA-1295596 8.970250e-04 3.047 0 0
p75NTR signals via NF-kB R-HSA-193639 8.970250e-04 3.047 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 9.115172e-04 3.040 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 9.115172e-04 3.040 0 0
Modulation by Mtb of host immune system R-HSA-9637628 9.115172e-04 3.040 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 9.852846e-04 3.006 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 9.879996e-04 3.005 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.001785e-03 2.999 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.082533e-03 2.966 0 0
DNA Replication R-HSA-69306 1.096712e-03 2.960 0 0
Negative regulation of FLT3 R-HSA-9706369 1.123992e-03 2.949 0 0
Nuclear import of Rev protein R-HSA-180746 1.137191e-03 2.944 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 1.303496e-03 2.885 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.390911e-03 2.857 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.400971e-03 2.854 0 0
Signaling by ERBB4 R-HSA-1236394 1.422348e-03 2.847 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.523243e-03 2.817 0 0
Metabolism of proteins R-HSA-392499 1.586752e-03 2.799 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.675274e-03 2.776 0 0
Pexophagy R-HSA-9664873 1.675274e-03 2.776 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.692765e-03 2.771 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.701843e-03 2.769 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.701843e-03 2.769 0 0
Signaling by Hippo R-HSA-2028269 1.701843e-03 2.769 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.843819e-03 2.734 0 0
Opioid Signalling R-HSA-111885 1.843819e-03 2.734 0 0
Adaptive Immune System R-HSA-1280218 1.853890e-03 2.732 0 0
Packaging Of Telomere Ends R-HSA-171306 1.855490e-03 2.732 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.031774e-03 2.692 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.060924e-03 2.686 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 2.166863e-03 2.664 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 2.166863e-03 2.664 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.472345e-03 2.607 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.472345e-03 2.607 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 2.439352e-03 2.613 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 2.425248e-03 2.615 0 0
Translesion Synthesis by POLH R-HSA-110320 2.472345e-03 2.607 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 2.737475e-03 2.563 0 0
Deubiquitination R-HSA-5688426 2.462513e-03 2.609 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 2.479607e-03 2.606 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 2.439352e-03 2.613 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 2.439352e-03 2.613 0 0
DNA Double Strand Break Response R-HSA-5693606 2.687895e-03 2.571 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.361779e-03 2.627 0 0
Negative regulation of MET activity R-HSA-6807004 2.940334e-03 2.532 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.737475e-03 2.563 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 2.798113e-03 2.553 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 2.662345e-03 2.575 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 2.425248e-03 2.615 0 0
NF-kB is activated and signals survival R-HSA-209560 2.798113e-03 2.553 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.282464e-03 2.642 0 0
Neuronal System R-HSA-112316 2.559895e-03 2.592 0 0
FLT3 Signaling R-HSA-9607240 2.737475e-03 2.563 0 0
Budding and maturation of HIV virion R-HSA-162588 3.249590e-03 2.488 0 0
G alpha (z) signalling events R-HSA-418597 3.250466e-03 2.488 0 0
Ub-specific processing proteases R-HSA-5689880 3.416783e-03 2.466 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.416828e-03 2.466 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 3.467045e-03 2.460 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 3.467045e-03 2.460 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 3.467045e-03 2.460 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 3.469132e-03 2.460 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 3.469132e-03 2.460 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 3.516417e-03 2.454 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 3.516417e-03 2.454 0 0
VLDLR internalisation and degradation R-HSA-8866427 3.516417e-03 2.454 0 0
IRAK1 recruits IKK complex R-HSA-937039 3.516417e-03 2.454 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 3.516417e-03 2.454 0 0
Signaling by EGFR R-HSA-177929 3.569179e-03 2.447 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.585492e-03 2.445 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 3.695373e-03 2.432 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 3.738379e-03 2.427 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 3.801228e-03 2.420 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 3.815303e-03 2.418 0 0
HATs acetylate histones R-HSA-3214847 3.844087e-03 2.415 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 3.911566e-03 2.408 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 4.062975e-03 2.391 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 4.062975e-03 2.391 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 4.062975e-03 2.391 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 4.062975e-03 2.391 0 0
Assembly Of The HIV Virion R-HSA-175474 4.062975e-03 2.391 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.062975e-03 2.391 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 4.078026e-03 2.390 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.184986e-03 2.378 0 0
Cyclin D associated events in G1 R-HSA-69231 4.217597e-03 2.375 0 0
G1 Phase R-HSA-69236 4.217597e-03 2.375 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 4.217597e-03 2.375 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 4.350649e-03 2.361 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 4.350649e-03 2.361 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 4.576662e-03 2.339 0 0
Interferon alpha/beta signaling R-HSA-909733 4.576662e-03 2.339 0 0
Reproduction R-HSA-1474165 4.639686e-03 2.334 0 0
Nucleosome assembly R-HSA-774815 4.667573e-03 2.331 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 4.667573e-03 2.331 0 0
DAG and IP3 signaling R-HSA-1489509 4.667573e-03 2.331 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 4.671932e-03 2.331 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 4.726075e-03 2.325 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 5.152810e-03 2.288 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.176083e-03 2.286 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 5.305699e-03 2.275 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 5.305699e-03 2.275 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 5.308896e-03 2.275 0 0
NRIF signals cell death from the nucleus R-HSA-205043 5.308896e-03 2.275 0 0
MAP kinase activation R-HSA-450294 5.540861e-03 2.256 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 5.550098e-03 2.256 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 5.703388e-03 2.244 0 0
Manipulation of host energy metabolism R-HSA-9636667 6.036825e-03 2.219 0 0
Translesion synthesis by POLI R-HSA-5656121 7.627809e-03 2.118 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 5.941812e-03 2.226 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 8.898466e-03 2.051 0 0
mRNA 3'-end processing R-HSA-72187 8.898466e-03 2.051 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 6.398856e-03 2.194 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 6.276668e-03 2.202 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 6.770132e-03 2.169 0 0
Translesion synthesis by REV1 R-HSA-110312 6.398856e-03 2.194 0 0
Signaling by ALK in cancer R-HSA-9700206 6.770132e-03 2.169 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 8.183112e-03 2.087 0 0
Breakdown of the nuclear lamina R-HSA-352238 6.036825e-03 2.219 0 0
RNA Polymerase I Transcription R-HSA-73864 6.425231e-03 2.192 0 0
Degradation of CDH1 R-HSA-9766229 6.836794e-03 2.165 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.166477e-03 2.088 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 7.172305e-03 2.144 0 0
Protein methylation R-HSA-8876725 6.398856e-03 2.194 0 0
HIV Life Cycle R-HSA-162587 8.308246e-03 2.080 0 0
HIV Infection R-HSA-162906 7.634793e-03 2.117 0 0
Hedgehog ligand biogenesis R-HSA-5358346 8.166477e-03 2.088 0 0
HCMV Late Events R-HSA-9610379 8.308246e-03 2.080 0 0
G-protein mediated events R-HSA-112040 8.894692e-03 2.051 0 0
Signaling by VEGF R-HSA-194138 8.462149e-03 2.073 0 0
Calmodulin induced events R-HSA-111933 6.631764e-03 2.178 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 7.068631e-03 2.151 0 0
CaM pathway R-HSA-111997 6.631764e-03 2.178 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.183112e-03 2.087 0 0
Vesicle-mediated transport R-HSA-5653656 7.693952e-03 2.114 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 6.836794e-03 2.165 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 6.836794e-03 2.165 0 0
Cleavage of the damaged purine R-HSA-110331 7.378042e-03 2.132 0 0
Depurination R-HSA-73927 8.183112e-03 2.087 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 7.627809e-03 2.118 0 0
Cellular response to chemical stress R-HSA-9711123 8.405514e-03 2.075 0 0
Regulation of BACH1 activity R-HSA-9708530 7.627809e-03 2.118 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 8.938095e-03 2.049 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 8.938095e-03 2.049 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.002582e-03 2.046 0 0
Translesion synthesis by POLK R-HSA-5655862 9.002582e-03 2.046 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 9.002582e-03 2.046 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 9.002582e-03 2.046 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 9.002582e-03 2.046 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 9.002582e-03 2.046 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.049415e-03 2.043 0 0
Stabilization of p53 R-HSA-69541 9.049415e-03 2.043 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 9.223966e-03 2.035 0 0
Late Phase of HIV Life Cycle R-HSA-162599 9.537920e-03 2.021 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 9.537920e-03 2.021 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.979357e-03 2.001 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 9.979357e-03 2.001 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.009423e-02 1.996 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 1.034263e-02 1.985 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.038755e-02 1.983 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.038755e-02 1.983 0 0
Diseases of Cellular Senescence R-HSA-9630747 1.046698e-02 1.980 0 0
Diseases of cellular response to stress R-HSA-9675132 1.046698e-02 1.980 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.052953e-02 1.978 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 1.052953e-02 1.978 0 0
Glycogen storage diseases R-HSA-3229121 1.052953e-02 1.978 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 1.097530e-02 1.960 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 1.097530e-02 1.960 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 1.097530e-02 1.960 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.105196e-02 1.957 0 0
Interleukin-17 signaling R-HSA-448424 1.105196e-02 1.957 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.128610e-02 1.947 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 1.164780e-02 1.934 0 0
Termination of translesion DNA synthesis R-HSA-5656169 1.164780e-02 1.934 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 1.164780e-02 1.934 0 0
Ephrin signaling R-HSA-3928664 1.221452e-02 1.913 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 1.221452e-02 1.913 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.252836e-02 1.902 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.262672e-02 1.899 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.300816e-02 1.886 0 0
Ca-dependent events R-HSA-111996 1.317445e-02 1.880 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.317445e-02 1.880 0 0
Depyrimidination R-HSA-73928 1.317445e-02 1.880 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 1.395687e-02 1.855 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.395687e-02 1.855 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 1.438214e-02 1.842 0 0
Signaling by FGFR4 R-HSA-5654743 1.438214e-02 1.842 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.438214e-02 1.842 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.447193e-02 1.839 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 1.447193e-02 1.839 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.447193e-02 1.839 0 0
Trafficking of AMPA receptors R-HSA-399719 1.447193e-02 1.839 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.447193e-02 1.839 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 1.447193e-02 1.839 0 0
Signaling by NOTCH4 R-HSA-9013694 1.450004e-02 1.839 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.487327e-02 1.828 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.487327e-02 1.828 0 0
Protein ubiquitination R-HSA-8852135 1.547209e-02 1.810 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 1.566479e-02 1.805 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.568456e-02 1.805 0 0
Chromosome Maintenance R-HSA-73886 1.597584e-02 1.797 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.607958e-02 1.794 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 1.607958e-02 1.794 0 0
Glycogen synthesis R-HSA-3322077 1.607958e-02 1.794 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.667472e-02 1.778 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 1.702448e-02 1.769 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.702448e-02 1.769 0 0
Signaling by FGFR3 R-HSA-5654741 1.702448e-02 1.769 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.772206e-02 1.751 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 1.772206e-02 1.751 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.772206e-02 1.751 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.772206e-02 1.751 0 0
PLC beta mediated events R-HSA-112043 1.779606e-02 1.750 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.779606e-02 1.750 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 1.826884e-02 1.738 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 1.826884e-02 1.738 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 1.826884e-02 1.738 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.831592e-02 1.737 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.831592e-02 1.737 0 0
Regulation of pyruvate metabolism R-HSA-9861718 1.846323e-02 1.734 0 0
PCP/CE pathway R-HSA-4086400 1.867081e-02 1.729 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.907014e-02 1.720 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.926127e-02 1.715 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.929908e-02 1.714 0 0
Striated Muscle Contraction R-HSA-390522 1.951418e-02 1.710 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.951418e-02 1.710 0 0
Vpu mediated degradation of CD4 R-HSA-180534 1.951418e-02 1.710 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.951418e-02 1.710 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 1.998298e-02 1.699 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.021655e-02 1.694 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.021655e-02 1.694 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.021655e-02 1.694 0 0
MyD88-independent TLR4 cascade R-HSA-166166 2.024190e-02 1.694 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 2.024190e-02 1.694 0 0
Signaling by GSK3beta mutants R-HSA-5339716 2.028718e-02 1.693 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 2.040675e-02 1.690 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.063453e-02 1.685 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.063453e-02 1.685 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.088951e-02 1.680 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.104988e-02 1.677 0 0
Signaling by MET R-HSA-6806834 2.104988e-02 1.677 0 0
Signaling by FGFR2 R-HSA-5654738 2.104988e-02 1.677 0 0
Dual Incision in GG-NER R-HSA-5696400 2.142121e-02 1.669 0 0
Mitophagy R-HSA-5205647 2.142121e-02 1.669 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.142121e-02 1.669 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 2.142121e-02 1.669 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 2.142121e-02 1.669 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 2.142121e-02 1.669 0 0
Ion transport by P-type ATPases R-HSA-936837 2.180728e-02 1.661 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.231661e-02 1.651 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.240677e-02 1.650 0 0
MTF1 activates gene expression R-HSA-5660489 2.240677e-02 1.650 0 0
mTORC1-mediated signalling R-HSA-166208 2.317995e-02 1.635 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.317995e-02 1.635 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.320661e-02 1.634 0 0
DNA Damage Bypass R-HSA-73893 2.327281e-02 1.633 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 2.340243e-02 1.631 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 2.344557e-02 1.630 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 2.344557e-02 1.630 0 0
Regulation of Apoptosis R-HSA-169911 2.344557e-02 1.630 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 2.395192e-02 1.621 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.395192e-02 1.621 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 2.395192e-02 1.621 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 2.395192e-02 1.621 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 2.395192e-02 1.621 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 2.395192e-02 1.621 0 0
Telomere Maintenance R-HSA-157579 2.443151e-02 1.612 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.443151e-02 1.612 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 2.452695e-02 1.610 0 0
Regulation of RAS by GAPs R-HSA-5658442 2.504635e-02 1.601 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.558948e-02 1.592 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.570170e-02 1.590 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.570170e-02 1.590 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.570170e-02 1.590 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 2.690500e-02 1.570 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 2.690778e-02 1.570 0 0
Degradation of DVL R-HSA-4641258 2.785499e-02 1.555 0 0
Degradation of AXIN R-HSA-4641257 2.785499e-02 1.555 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 2.785499e-02 1.555 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 2.785499e-02 1.555 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.785499e-02 1.555 0 0
Regulated Necrosis R-HSA-5218859 2.807437e-02 1.552 0 0
Deadenylation of mRNA R-HSA-429947 2.882072e-02 1.540 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 2.885862e-02 1.540 0 0
Orc1 removal from chromatin R-HSA-68949 2.885862e-02 1.540 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 2.946254e-02 1.531 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.975181e-02 1.526 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 3.024391e-02 1.519 0 0
Ion channel transport R-HSA-983712 3.089132e-02 1.510 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 3.090027e-02 1.510 0 0
Sema4D in semaphorin signaling R-HSA-400685 3.192018e-02 1.496 0 0
Interleukin-7 signaling R-HSA-1266695 3.192018e-02 1.496 0 0
Malate-aspartate shuttle R-HSA-9856872 3.228040e-02 1.491 0 0
Pentose phosphate pathway R-HSA-71336 3.275790e-02 1.485 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 3.303402e-02 1.481 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 3.303402e-02 1.481 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 3.735312e-02 1.428 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 3.735312e-02 1.428 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 3.735312e-02 1.428 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.791170e-02 1.421 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 4.681554e-02 1.330 0 0
Disinhibition of SNARE formation R-HSA-114516 5.639654e-02 1.249 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.639654e-02 1.249 0 0
Type I hemidesmosome assembly R-HSA-446107 6.659188e-02 1.177 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.659188e-02 1.177 0 0
Formation of annular gap junctions R-HSA-196025 6.659188e-02 1.177 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.659188e-02 1.177 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 3.693948e-02 1.433 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 3.693948e-02 1.433 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 4.192318e-02 1.378 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 3.868394e-02 1.412 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 3.758258e-02 1.425 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 5.750179e-02 1.240 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 5.750179e-02 1.240 0 0
Dual incision in TC-NER R-HSA-6782135 4.251269e-02 1.371 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 6.350109e-02 1.197 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.816658e-02 1.418 0 0
Chromatin modifying enzymes R-HSA-3247509 3.695252e-02 1.432 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 3.526109e-02 1.453 0 0
Chromatin organization R-HSA-4839726 5.602871e-02 1.252 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 3.758258e-02 1.425 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 3.791170e-02 1.421 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 6.659188e-02 1.177 0 0
Degradation of CRY and PER proteins R-HSA-9932298 4.106353e-02 1.387 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 6.118183e-02 1.213 0 0
Ca2+ pathway R-HSA-4086398 3.749145e-02 1.426 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 3.639451e-02 1.439 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 6.498229e-02 1.187 0 0
Interleukin-23 signaling R-HSA-9020933 6.659188e-02 1.177 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 4.241205e-02 1.373 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 3.350615e-02 1.475 0 0
Regulation of mitotic cell cycle R-HSA-453276 3.350615e-02 1.475 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.620432e-02 1.335 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.498229e-02 1.187 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 6.350109e-02 1.197 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.234951e-02 1.373 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.106353e-02 1.387 0 0
snRNP Assembly R-HSA-191859 4.512300e-02 1.346 0 0
Metabolism of non-coding RNA R-HSA-194441 4.512300e-02 1.346 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.730285e-02 1.325 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 4.722612e-02 1.326 0 0
Rap1 signalling R-HSA-392517 6.498229e-02 1.187 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 5.750179e-02 1.240 0 0
Downstream TCR signaling R-HSA-202424 3.804567e-02 1.420 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 5.741058e-02 1.241 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 4.106353e-02 1.387 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 4.106353e-02 1.387 0 0
Cellular response to hypoxia R-HSA-1234174 6.285456e-02 1.202 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.340298e-02 1.476 0 0
G1/S Transition R-HSA-69206 4.466563e-02 1.350 0 0
Platelet calcium homeostasis R-HSA-418360 4.620432e-02 1.335 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 5.256424e-02 1.279 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.967044e-02 1.402 0 0
Innate Immune System R-HSA-168249 4.210374e-02 1.376 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 6.659188e-02 1.177 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 6.350109e-02 1.197 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 5.395255e-02 1.268 0 0
tRNA processing in the nucleus R-HSA-6784531 5.354278e-02 1.271 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 5.889773e-02 1.230 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.539838e-02 1.451 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.816658e-02 1.418 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.520763e-02 1.453 0 0
Ion homeostasis R-HSA-5578775 3.758258e-02 1.425 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.868394e-02 1.412 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 3.816658e-02 1.418 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 5.395255e-02 1.268 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.350615e-02 1.475 0 0
Interleukin-1 family signaling R-HSA-446652 6.423228e-02 1.192 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.791170e-02 1.421 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 5.639654e-02 1.249 0 0
Signaling by FGFR R-HSA-190236 5.988649e-02 1.223 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 5.395255e-02 1.268 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 5.395255e-02 1.268 0 0
Signaling by FGFR1 R-HSA-5654736 3.758258e-02 1.425 0 0
Signaling by NOTCH3 R-HSA-9012852 3.526109e-02 1.453 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 5.482915e-02 1.261 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 5.934394e-02 1.227 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 3.758258e-02 1.425 0 0
Suppression of phagosomal maturation R-HSA-9637687 3.520763e-02 1.453 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 5.489447e-02 1.260 0 0
Regulation of gene expression in beta cells R-HSA-210745 4.620432e-02 1.335 0 0
Interleukin-1 signaling R-HSA-9020702 6.771245e-02 1.169 0 0
Effects of PIP2 hydrolysis R-HSA-114508 6.828760e-02 1.166 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 6.846836e-02 1.165 0 0
Homology Directed Repair R-HSA-5693538 6.892049e-02 1.162 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 6.893285e-02 1.162 0 0
Amplification of signal from the kinetochores R-HSA-141424 7.091983e-02 1.149 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 7.091983e-02 1.149 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.145705e-02 1.146 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.145705e-02 1.146 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 7.149016e-02 1.146 0 0
Signal transduction by L1 R-HSA-445144 7.149016e-02 1.146 0 0
Nephrin family interactions R-HSA-373753 7.149016e-02 1.146 0 0
Metabolism of amino acids and derivatives R-HSA-71291 7.319804e-02 1.136 0 0
Calnexin/calreticulin cycle R-HSA-901042 7.325496e-02 1.135 0 0
Signaling by NOTCH2 R-HSA-1980145 7.325496e-02 1.135 0 0
TICAM1 deficiency - HSE R-HSA-5602566 7.331318e-02 1.135 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 7.331318e-02 1.135 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 7.331318e-02 1.135 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 7.331318e-02 1.135 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 7.331318e-02 1.135 0 0
Hereditary fructose intolerance R-HSA-5657560 7.331318e-02 1.135 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 7.331318e-02 1.135 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 7.331318e-02 1.135 0 0
Inhibition of PKR R-HSA-169131 7.331318e-02 1.135 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 7.404716e-02 1.130 0 0
Pyruvate metabolism R-HSA-70268 7.725463e-02 1.112 0 0
Lipophagy R-HSA-9613354 7.734245e-02 1.112 0 0
Gap junction degradation R-HSA-190873 7.734245e-02 1.112 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 7.734245e-02 1.112 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 7.734245e-02 1.112 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 7.734245e-02 1.112 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 7.734245e-02 1.112 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 7.734245e-02 1.112 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 7.734245e-02 1.112 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 7.734245e-02 1.112 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 7.734245e-02 1.112 0 0
Unfolded Protein Response (UPR) R-HSA-381119 7.876285e-02 1.104 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.941076e-02 1.100 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.941076e-02 1.100 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 8.036354e-02 1.095 0 0
Extracellular matrix organization R-HSA-1474244 8.289032e-02 1.081 0 0
Platelet homeostasis R-HSA-418346 8.516907e-02 1.070 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 8.597842e-02 1.066 0 0
Regulation of PTEN stability and activity R-HSA-8948751 8.597842e-02 1.066 0 0
Base Excision Repair R-HSA-73884 8.735637e-02 1.059 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 8.805787e-02 1.055 0 0
MAPK3 (ERK1) activation R-HSA-110056 8.859272e-02 1.053 0 0
Regulation of CDH11 function R-HSA-9762292 8.859272e-02 1.053 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 8.859272e-02 1.053 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.205101e-02 1.036 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.205101e-02 1.036 0 0
IRE1alpha activates chaperones R-HSA-381070 9.448768e-02 1.025 0 0
TCR signaling R-HSA-202403 9.814237e-02 1.008 0 0
TNF signaling R-HSA-75893 1.000776e-01 1.000 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.000776e-01 1.000 0 0
Syndecan interactions R-HSA-3000170 1.002184e-01 0.999 0 0
Signaling by APC mutants R-HSA-4839744 1.002905e-01 0.999 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 1.002905e-01 0.999 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 1.002905e-01 0.999 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 1.002905e-01 0.999 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.003255e-01 0.999 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.007038e-01 0.997 0 0
Plasma lipoprotein clearance R-HSA-8964043 1.007038e-01 0.997 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.030731e-01 0.987 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.065365e-01 0.973 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.066920e-01 0.972 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.066920e-01 0.972 0 0
Glycogen metabolism R-HSA-8982491 1.066920e-01 0.972 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 1.079320e-01 0.967 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 1.079320e-01 0.967 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 1.079320e-01 0.967 0 0
TRAF3 deficiency - HSE R-HSA-5602571 1.079320e-01 0.967 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 1.079320e-01 0.967 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.079320e-01 0.967 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 1.079320e-01 0.967 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.080230e-01 0.966 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 1.080230e-01 0.966 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.123867e-01 0.949 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.123867e-01 0.949 0 0
Signaling by AMER1 mutants R-HSA-4839748 1.123867e-01 0.949 0 0
Signaling by AXIN mutants R-HSA-4839735 1.123867e-01 0.949 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.123867e-01 0.949 0 0
Integration of provirus R-HSA-162592 1.123867e-01 0.949 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.123867e-01 0.949 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.128375e-01 0.948 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.133640e-01 0.946 0 0
ABC transporter disorders R-HSA-5619084 1.134440e-01 0.945 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.145844e-01 0.941 0 0
Peroxisomal protein import R-HSA-9033241 1.152566e-01 0.938 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 1.152566e-01 0.938 0 0
HDMs demethylate histones R-HSA-3214842 1.160551e-01 0.935 0 0
Tight junction interactions R-HSA-420029 1.160551e-01 0.935 0 0
Gene expression (Transcription) R-HSA-74160 1.169829e-01 0.932 0 0
Sensory processing of sound R-HSA-9659379 1.180010e-01 0.928 0 0
Translation of Structural Proteins R-HSA-9683701 1.191357e-01 0.924 0 0
Protein localization R-HSA-9609507 1.222888e-01 0.913 0 0
Myogenesis R-HSA-525793 1.243035e-01 0.906 0 0
GRB2 events in EGFR signaling R-HSA-179812 1.248355e-01 0.904 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.248355e-01 0.904 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.255824e-01 0.901 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 1.255824e-01 0.901 0 0
MTOR signalling R-HSA-165159 1.255824e-01 0.901 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.259493e-01 0.900 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 1.259493e-01 0.900 0 0
Developmental Cell Lineages R-HSA-9734767 1.280097e-01 0.893 0 0
Signaling by SCF-KIT R-HSA-1433557 1.321730e-01 0.879 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.327568e-01 0.877 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 1.327568e-01 0.877 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.347551e-01 0.870 0 0
ABC-family proteins mediated transport R-HSA-382556 1.347551e-01 0.870 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.370797e-01 0.863 0 0
Frs2-mediated activation R-HSA-170968 1.375937e-01 0.861 0 0
Interleukin-6 signaling R-HSA-1059683 1.375937e-01 0.861 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.375937e-01 0.861 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 1.375937e-01 0.861 0 0
Netrin-1 signaling R-HSA-373752 1.389026e-01 0.857 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 1.412597e-01 0.850 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.412597e-01 0.850 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 1.412597e-01 0.850 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 1.412597e-01 0.850 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 1.412597e-01 0.850 0 0
Potassium transport channels R-HSA-1296067 1.412597e-01 0.850 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 1.412597e-01 0.850 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 1.412597e-01 0.850 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.412597e-01 0.850 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 1.412597e-01 0.850 0 0
Inflammasomes R-HSA-622312 1.414038e-01 0.850 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.421094e-01 0.847 0 0
Somitogenesis R-HSA-9824272 1.457665e-01 0.836 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 1.457665e-01 0.836 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.457665e-01 0.836 0 0
Regulation of TP53 Activity R-HSA-5633007 1.463625e-01 0.835 0 0
DARPP-32 events R-HSA-180024 1.502332e-01 0.823 0 0
Glucagon-type ligand receptors R-HSA-420092 1.502332e-01 0.823 0 0
Regulation of KIT signaling R-HSA-1433559 1.506210e-01 0.822 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.527596e-01 0.816 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 1.528988e-01 0.816 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.575793e-01 0.803 0 0
Interleukin-37 signaling R-HSA-9008059 1.592336e-01 0.798 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.605718e-01 0.794 0 0
Nucleotide Excision Repair R-HSA-5696398 1.623751e-01 0.789 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.638795e-01 0.785 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.638795e-01 0.785 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.638795e-01 0.785 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 1.638795e-01 0.785 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.638795e-01 0.785 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.638795e-01 0.785 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.663251e-01 0.779 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.666854e-01 0.778 0 0
GPER1 signaling R-HSA-9634597 1.671136e-01 0.777 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.671136e-01 0.777 0 0
Synthesis of DNA R-HSA-69239 1.721084e-01 0.764 0 0
MET activates STAT3 R-HSA-8875791 1.733441e-01 0.761 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 1.733441e-01 0.761 0 0
Classical Kir channels R-HSA-1296053 1.733441e-01 0.761 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 1.733441e-01 0.761 0 0
Signalling to STAT3 R-HSA-198745 1.733441e-01 0.761 0 0
Intracellular oxygen transport R-HSA-8981607 1.733441e-01 0.761 0 0
The NLRP1 inflammasome R-HSA-844455 1.733441e-01 0.761 0 0
FasL/ CD95L signaling R-HSA-75157 1.733441e-01 0.761 0 0
ER-Phagosome pathway R-HSA-1236974 1.737475e-01 0.760 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.744640e-01 0.758 0 0
Stimuli-sensing channels R-HSA-2672351 1.770682e-01 0.752 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.773338e-01 0.751 0 0
Prolonged ERK activation events R-HSA-169893 1.773338e-01 0.751 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.773338e-01 0.751 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 1.773338e-01 0.751 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 1.773338e-01 0.751 0 0
Inwardly rectifying K+ channels R-HSA-1296065 1.777025e-01 0.750 0 0
Signaling by WNT in cancer R-HSA-4791275 1.777025e-01 0.750 0 0
G0 and Early G1 R-HSA-1538133 1.777025e-01 0.750 0 0
Leishmania infection R-HSA-9658195 1.793659e-01 0.746 0 0
Parasitic Infection Pathways R-HSA-9824443 1.793659e-01 0.746 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.848896e-01 0.733 0 0
Hedgehog 'on' state R-HSA-5632684 1.855576e-01 0.732 0 0
Integrin signaling R-HSA-354192 1.871487e-01 0.728 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 1.909509e-01 0.719 0 0
Response to metal ions R-HSA-5660526 1.909509e-01 0.719 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 1.967216e-01 0.706 0 0
Glutamate and glutamine metabolism R-HSA-8964539 1.967216e-01 0.706 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.985512e-01 0.702 0 0
Cardiac conduction R-HSA-5576891 2.016897e-01 0.695 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.042317e-01 0.690 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.042317e-01 0.690 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 2.042317e-01 0.690 0 0
Signaling by MAP2K mutants R-HSA-9652169 2.042317e-01 0.690 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.042317e-01 0.690 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.042317e-01 0.690 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 2.042317e-01 0.690 0 0
NADE modulates death signalling R-HSA-205025 2.042317e-01 0.690 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.042317e-01 0.690 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.047000e-01 0.689 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 2.047000e-01 0.689 0 0
DNA Repair R-HSA-73894 2.052184e-01 0.688 0 0
Mitochondrial protein degradation R-HSA-9837999 2.079741e-01 0.682 0 0
Signalling to ERKs R-HSA-187687 2.162042e-01 0.665 0 0
PERK regulates gene expression R-HSA-381042 2.162042e-01 0.665 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.185522e-01 0.660 0 0
PKA activation in glucagon signalling R-HSA-164378 2.185522e-01 0.660 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.185522e-01 0.660 0 0
Nephron development R-HSA-9831926 2.185522e-01 0.660 0 0
Translation of Structural Proteins R-HSA-9694635 2.254149e-01 0.647 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 2.260931e-01 0.646 0 0
Integration of energy metabolism R-HSA-163685 2.314569e-01 0.636 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.324808e-01 0.634 0 0
The NLRP3 inflammasome R-HSA-844456 2.324808e-01 0.634 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 2.324808e-01 0.634 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.339670e-01 0.631 0 0
G2 Phase R-HSA-68911 2.339670e-01 0.631 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 2.339670e-01 0.631 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.339670e-01 0.631 0 0
PTK6 Activates STAT3 R-HSA-8849474 2.339670e-01 0.631 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 2.339670e-01 0.631 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.339670e-01 0.631 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.339670e-01 0.631 0 0
Regulation of insulin secretion R-HSA-422356 2.381576e-01 0.623 0 0
Signaling by TGFB family members R-HSA-9006936 2.413477e-01 0.617 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.443496e-01 0.612 0 0
RNA Polymerase II Transcription R-HSA-73857 2.444993e-01 0.612 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 2.461151e-01 0.609 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.464606e-01 0.608 0 0
Protein hydroxylation R-HSA-9629569 2.464606e-01 0.608 0 0
Asparagine N-linked glycosylation R-HSA-446203 2.502904e-01 0.602 0 0
Regulation of beta-cell development R-HSA-186712 2.530726e-01 0.597 0 0
Signaling by ALK R-HSA-201556 2.562286e-01 0.591 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 2.604686e-01 0.584 0 0
Early Phase of HIV Life Cycle R-HSA-162594 2.604686e-01 0.584 0 0
ERK/MAPK targets R-HSA-198753 2.604686e-01 0.584 0 0
Basigin interactions R-HSA-210991 2.604686e-01 0.584 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.604686e-01 0.584 0 0
RAB geranylgeranylation R-HSA-8873719 2.613276e-01 0.583 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.613276e-01 0.583 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.613276e-01 0.583 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.613276e-01 0.583 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.613276e-01 0.583 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.613276e-01 0.583 0 0
Plus-strand DNA synthesis R-HSA-164525 2.625929e-01 0.581 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.625929e-01 0.581 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.625929e-01 0.581 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.625929e-01 0.581 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.625929e-01 0.581 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.625929e-01 0.581 0 0
Pentose phosphate pathway disease R-HSA-6791465 2.625929e-01 0.581 0 0
Phosphorylation of Emi1 R-HSA-176417 2.625929e-01 0.581 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.625929e-01 0.581 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 2.625929e-01 0.581 0 0
TRAIL signaling R-HSA-75158 2.625929e-01 0.581 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.625929e-01 0.581 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 2.675153e-01 0.573 0 0
Formation of paraxial mesoderm R-HSA-9793380 2.696333e-01 0.569 0 0
Post-translational protein modification R-HSA-597592 2.703202e-01 0.568 0 0
Mitochondrial calcium ion transport R-HSA-8949215 2.744831e-01 0.561 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.744831e-01 0.561 0 0
Ribavirin ADME R-HSA-9755088 2.744831e-01 0.561 0 0
Formation of the cornified envelope R-HSA-6809371 2.752213e-01 0.560 0 0
Mitochondrial protein import R-HSA-1268020 2.779849e-01 0.556 0 0
Toll-like Receptor Cascades R-HSA-168898 2.818287e-01 0.550 0 0
RSV-host interactions R-HSA-9833110 2.824026e-01 0.549 0 0
FGFR2 alternative splicing R-HSA-6803529 2.884841e-01 0.540 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 2.884841e-01 0.540 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 2.884841e-01 0.540 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 2.884841e-01 0.540 0 0
Signaling by KIT in disease R-HSA-9669938 2.884841e-01 0.540 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 2.891883e-01 0.539 0 0
Signaling by LTK in cancer R-HSA-9842640 2.901508e-01 0.537 0 0
Uncoating of the HIV Virion R-HSA-162585 2.901508e-01 0.537 0 0
G2/M DNA replication checkpoint R-HSA-69478 2.901508e-01 0.537 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 2.901508e-01 0.537 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 2.901508e-01 0.537 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 2.901508e-01 0.537 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.901508e-01 0.537 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 2.901508e-01 0.537 0 0
VLDL assembly R-HSA-8866423 2.901508e-01 0.537 0 0
Nef and signal transduction R-HSA-164944 2.901508e-01 0.537 0 0
Activation of GABAB receptors R-HSA-991365 2.971493e-01 0.527 0 0
GABA B receptor activation R-HSA-977444 2.971493e-01 0.527 0 0
S Phase R-HSA-69242 3.004993e-01 0.522 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.024531e-01 0.519 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.047434e-01 0.516 0 0
Antigen processing-Cross presentation R-HSA-1236975 3.084643e-01 0.511 0 0
Leishmania parasite growth and survival R-HSA-9664433 3.114213e-01 0.507 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 3.114213e-01 0.507 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 3.163731e-01 0.500 0 0
Interleukin-6 family signaling R-HSA-6783589 3.163731e-01 0.500 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 3.166804e-01 0.499 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 3.166804e-01 0.499 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 3.166804e-01 0.499 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.166804e-01 0.499 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.166804e-01 0.499 0 0
Recycling of eIF2:GDP R-HSA-72731 3.166804e-01 0.499 0 0
DAG1 core M1 glycosylations R-HSA-8932506 3.166804e-01 0.499 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.166804e-01 0.499 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 3.166804e-01 0.499 0 0
SOS-mediated signalling R-HSA-112412 3.166804e-01 0.499 0 0
LDL remodeling R-HSA-8964041 3.166804e-01 0.499 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 3.166804e-01 0.499 0 0
CHL1 interactions R-HSA-447041 3.166804e-01 0.499 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.166804e-01 0.499 0 0
Proteasome assembly R-HSA-9907900 3.177677e-01 0.498 0 0
Disorders of transmembrane transporters R-HSA-5619115 3.212090e-01 0.493 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 3.280879e-01 0.484 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 3.280879e-01 0.484 0 0
G protein gated Potassium channels R-HSA-1296059 3.302281e-01 0.481 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 3.302281e-01 0.481 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 3.302281e-01 0.481 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 3.302281e-01 0.481 0 0
Death Receptor Signaling R-HSA-73887 3.338564e-01 0.476 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 3.373192e-01 0.472 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 3.384054e-01 0.471 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 3.401713e-01 0.468 0 0
Reverse Transcription of HIV RNA R-HSA-162589 3.422201e-01 0.466 0 0
Minus-strand DNA synthesis R-HSA-164516 3.422201e-01 0.466 0 0
DAG1 core M2 glycosylations R-HSA-8932504 3.422201e-01 0.466 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.422201e-01 0.466 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 3.422201e-01 0.466 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 3.422201e-01 0.466 0 0
Activation of RAS in B cells R-HSA-1169092 3.422201e-01 0.466 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.422201e-01 0.466 0 0
Interleukin-9 signaling R-HSA-8985947 3.422201e-01 0.466 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.440036e-01 0.463 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 3.440036e-01 0.463 0 0
TRP channels R-HSA-3295583 3.440036e-01 0.463 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 3.440036e-01 0.463 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 3.482214e-01 0.458 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 3.482214e-01 0.458 0 0
Generic Transcription Pathway R-HSA-212436 3.548474e-01 0.450 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.576863e-01 0.446 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.590034e-01 0.445 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 3.629623e-01 0.440 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 3.629623e-01 0.440 0 0
ALK mutants bind TKIs R-HSA-9700645 3.668067e-01 0.436 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 3.668067e-01 0.436 0 0
Interleukin-21 signaling R-HSA-9020958 3.668067e-01 0.436 0 0
ARMS-mediated activation R-HSA-170984 3.668067e-01 0.436 0 0
Calcineurin activates NFAT R-HSA-2025928 3.668067e-01 0.436 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.668067e-01 0.436 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.668067e-01 0.436 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.668067e-01 0.436 0 0
Telomere Extension By Telomerase R-HSA-171319 3.712639e-01 0.430 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 3.712639e-01 0.430 0 0
PTEN Regulation R-HSA-6807070 3.837738e-01 0.416 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 3.847251e-01 0.415 0 0
Iron uptake and transport R-HSA-917937 3.885671e-01 0.411 0 0
The phototransduction cascade R-HSA-2514856 3.897081e-01 0.409 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 3.899170e-01 0.409 0 0
Parasite infection R-HSA-9664407 3.899170e-01 0.409 0 0
Leishmania phagocytosis R-HSA-9664417 3.899170e-01 0.409 0 0
Binding and entry of HIV virion R-HSA-173107 3.904758e-01 0.408 0 0
2-LTR circle formation R-HSA-164843 3.904758e-01 0.408 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 3.904758e-01 0.408 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 3.904758e-01 0.408 0 0
DNA replication initiation R-HSA-68952 3.904758e-01 0.408 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.904758e-01 0.408 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 3.904758e-01 0.408 0 0
Signaling by Leptin R-HSA-2586552 3.904758e-01 0.408 0 0
Interleukin-27 signaling R-HSA-9020956 3.904758e-01 0.408 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 3.904758e-01 0.408 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 3.951319e-01 0.403 0 0
Signaling by NOTCH1 R-HSA-1980143 3.970752e-01 0.401 0 0
DAP12 signaling R-HSA-2424491 3.980597e-01 0.400 0 0
Activation of the pre-replicative complex R-HSA-68962 3.980597e-01 0.400 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 3.998669e-01 0.398 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 3.998669e-01 0.398 0 0
FOXO-mediated transcription R-HSA-9614085 4.078506e-01 0.389 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 4.085339e-01 0.389 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.099783e-01 0.387 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 4.112584e-01 0.386 0 0
Downstream signal transduction R-HSA-186763 4.112584e-01 0.386 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.119792e-01 0.385 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 4.132615e-01 0.384 0 0
DAG1 core M3 glycosylations R-HSA-8932505 4.132615e-01 0.384 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.132615e-01 0.384 0 0
vRNP Assembly R-HSA-192905 4.132615e-01 0.384 0 0
Chylomicron assembly R-HSA-8963888 4.132615e-01 0.384 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 4.132615e-01 0.384 0 0
Bicarbonate transporters R-HSA-425381 4.132615e-01 0.384 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 4.132615e-01 0.384 0 0
PECAM1 interactions R-HSA-210990 4.132615e-01 0.384 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 4.132615e-01 0.384 0 0
Interleukin-2 signaling R-HSA-9020558 4.132615e-01 0.384 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.132615e-01 0.384 0 0
FCERI mediated NF-kB activation R-HSA-2871837 4.206231e-01 0.376 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 4.226865e-01 0.374 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.351967e-01 0.361 0 0
Plasmalogen biosynthesis R-HSA-75896 4.351967e-01 0.361 0 0
ERKs are inactivated R-HSA-202670 4.351967e-01 0.361 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 4.351967e-01 0.361 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 4.351967e-01 0.361 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 4.351967e-01 0.361 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 4.351967e-01 0.361 0 0
Nuclear RNA decay R-HSA-9930044 4.372149e-01 0.359 0 0
Signaling by NTRKs R-HSA-166520 4.450891e-01 0.352 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 4.499583e-01 0.347 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.563132e-01 0.341 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.563132e-01 0.341 0 0
MET activates RAS signaling R-HSA-8851805 4.563132e-01 0.341 0 0
Interleukin-15 signaling R-HSA-8983432 4.563132e-01 0.341 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.563132e-01 0.341 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 4.563132e-01 0.341 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 4.563132e-01 0.341 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 4.563132e-01 0.341 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 4.563132e-01 0.341 0 0
Interleukin-35 Signalling R-HSA-8984722 4.563132e-01 0.341 0 0
OAS antiviral response R-HSA-8983711 4.563132e-01 0.341 0 0
MITF-M-dependent gene expression R-HSA-9856651 4.572588e-01 0.340 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 4.625367e-01 0.335 0 0
Signal amplification R-HSA-392518 4.625367e-01 0.335 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 4.625367e-01 0.335 0 0
G alpha (i) signalling events R-HSA-418594 4.634563e-01 0.334 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 4.766414e-01 0.322 0 0
Processing of SMDT1 R-HSA-8949664 4.766414e-01 0.322 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 4.766414e-01 0.322 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 4.766414e-01 0.322 0 0
Formation of axial mesoderm R-HSA-9796292 4.766414e-01 0.322 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 4.766414e-01 0.322 0 0
GABA receptor activation R-HSA-977443 4.790147e-01 0.320 0 0
G1/S-Specific Transcription R-HSA-69205 4.871771e-01 0.312 0 0
RET signaling R-HSA-8853659 4.871771e-01 0.312 0 0
Aquaporin-mediated transport R-HSA-445717 4.885765e-01 0.311 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 4.886514e-01 0.311 0 0
Circadian clock R-HSA-9909396 4.943902e-01 0.306 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 4.962107e-01 0.304 0 0
CRMPs in Sema3A signaling R-HSA-399956 4.962107e-01 0.304 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 4.962107e-01 0.304 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 4.962107e-01 0.304 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 4.962107e-01 0.304 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 4.962107e-01 0.304 0 0
Signaling by FGFR4 in disease R-HSA-5655291 4.962107e-01 0.304 0 0
Signaling by PDGF R-HSA-186797 4.980521e-01 0.303 0 0
Inositol phosphate metabolism R-HSA-1483249 5.096644e-01 0.293 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 5.150495e-01 0.288 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.150495e-01 0.288 0 0
G beta:gamma signalling through BTK R-HSA-8964315 5.150495e-01 0.288 0 0
p38MAPK events R-HSA-171007 5.150495e-01 0.288 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.150495e-01 0.288 0 0
Erythropoietin activates RAS R-HSA-9027284 5.150495e-01 0.288 0 0
DCC mediated attractive signaling R-HSA-418885 5.150495e-01 0.288 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 5.205739e-01 0.284 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 5.227833e-01 0.282 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.331849e-01 0.273 0 0
Phosphorylation of the APC/C R-HSA-176412 5.331849e-01 0.273 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.331849e-01 0.273 0 0
Fructose catabolism R-HSA-70350 5.331849e-01 0.273 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.331849e-01 0.273 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.331849e-01 0.273 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.331849e-01 0.273 0 0
Attachment and Entry R-HSA-9678110 5.331849e-01 0.273 0 0
Interleukin-2 family signaling R-HSA-451927 5.342778e-01 0.272 0 0
PIP3 activates AKT signaling R-HSA-1257604 5.385230e-01 0.269 0 0
Kidney development R-HSA-9830369 5.440347e-01 0.264 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 5.443541e-01 0.264 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 5.455810e-01 0.263 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 5.506432e-01 0.259 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.506432e-01 0.259 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 5.506432e-01 0.259 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.506432e-01 0.259 0 0
Disorders of Developmental Biology R-HSA-9675151 5.506432e-01 0.259 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 5.506432e-01 0.259 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 5.515235e-01 0.258 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 5.529344e-01 0.257 0 0
Signaling by FGFR1 in disease R-HSA-5655302 5.566912e-01 0.254 0 0
Rab regulation of trafficking R-HSA-9007101 5.579030e-01 0.253 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 5.590951e-01 0.253 0 0
Collagen formation R-HSA-1474290 5.590951e-01 0.253 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 5.674495e-01 0.246 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 5.674495e-01 0.246 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 5.674495e-01 0.246 0 0
Uptake and function of anthrax toxins R-HSA-5210891 5.674495e-01 0.246 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 5.676071e-01 0.246 0 0
TBC/RABGAPs R-HSA-8854214 5.783275e-01 0.238 0 0
ECM proteoglycans R-HSA-3000178 5.790033e-01 0.237 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 5.836283e-01 0.234 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 5.836283e-01 0.234 0 0
GAB1 signalosome R-HSA-180292 5.836283e-01 0.234 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 5.836283e-01 0.234 0 0
Presynaptic function of Kainate receptors R-HSA-500657 5.836283e-01 0.234 0 0
Platelet sensitization by LDL R-HSA-432142 5.836283e-01 0.234 0 0
Apoptotic factor-mediated response R-HSA-111471 5.836283e-01 0.234 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 5.836283e-01 0.234 0 0
Tie2 Signaling R-HSA-210993 5.836283e-01 0.234 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 5.836283e-01 0.234 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 5.874775e-01 0.231 0 0
DAP12 interactions R-HSA-2172127 5.888520e-01 0.230 0 0
Post-translational protein phosphorylation R-HSA-8957275 5.958840e-01 0.225 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.972985e-01 0.224 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 5.991801e-01 0.222 0 0
Germ layer formation at gastrulation R-HSA-9754189 5.992029e-01 0.222 0 0
Specification of the neural plate border R-HSA-9834899 5.992029e-01 0.222 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 5.992029e-01 0.222 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 5.992029e-01 0.222 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 5.992029e-01 0.222 0 0
STING mediated induction of host immune responses R-HSA-1834941 5.992029e-01 0.222 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 5.992029e-01 0.222 0 0
Signaling by TGFBR3 R-HSA-9839373 6.093118e-01 0.215 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.093118e-01 0.215 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.093118e-01 0.215 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 6.141959e-01 0.212 0 0
Co-inhibition by CTLA4 R-HSA-389513 6.141959e-01 0.212 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 6.141959e-01 0.212 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.141959e-01 0.212 0 0
Creatine metabolism R-HSA-71288 6.141959e-01 0.212 0 0
Formation of definitive endoderm R-HSA-9823730 6.141959e-01 0.212 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.192474e-01 0.208 0 0
G-protein activation R-HSA-202040 6.286289e-01 0.202 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 6.286289e-01 0.202 0 0
Signalling to RAS R-HSA-167044 6.286289e-01 0.202 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.286289e-01 0.202 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.286289e-01 0.202 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.286289e-01 0.202 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 6.286289e-01 0.202 0 0
Nuclear Receptor transcription pathway R-HSA-383280 6.359767e-01 0.197 0 0
G alpha (q) signalling events R-HSA-416476 6.404582e-01 0.194 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 6.425227e-01 0.192 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.425227e-01 0.192 0 0
Serine metabolism R-HSA-977347 6.425227e-01 0.192 0 0
Androgen biosynthesis R-HSA-193048 6.425227e-01 0.192 0 0
Attachment and Entry R-HSA-9694614 6.425227e-01 0.192 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 6.425227e-01 0.192 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 6.466212e-01 0.189 0 0
Azathioprine ADME R-HSA-9748787 6.478832e-01 0.189 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 6.558976e-01 0.183 0 0
Fructose metabolism R-HSA-5652084 6.558976e-01 0.183 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 6.558976e-01 0.183 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.586857e-01 0.181 0 0
Interferon gamma signaling R-HSA-877300 6.658970e-01 0.177 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 6.660080e-01 0.177 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 6.687729e-01 0.175 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.687729e-01 0.175 0 0
Interleukin-20 family signaling R-HSA-8854691 6.687729e-01 0.175 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.687729e-01 0.175 0 0
Growth hormone receptor signaling R-HSA-982772 6.687729e-01 0.175 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 6.747846e-01 0.171 0 0
Nucleotide biosynthesis R-HSA-8956320 6.747846e-01 0.171 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 6.811672e-01 0.167 0 0
Thromboxane signalling through TP receptor R-HSA-428930 6.811672e-01 0.167 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 6.811672e-01 0.167 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 6.811672e-01 0.167 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 6.811672e-01 0.167 0 0
Plasma lipoprotein assembly R-HSA-8963898 6.811672e-01 0.167 0 0
Complex III assembly R-HSA-9865881 6.811672e-01 0.167 0 0
Mitochondrial RNA degradation R-HSA-9836573 6.811672e-01 0.167 0 0
TGFBR3 expression R-HSA-9839394 6.930984e-01 0.159 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 6.930984e-01 0.159 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 6.930984e-01 0.159 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 6.930984e-01 0.159 0 0
Formation of the nephric duct R-HSA-9830364 6.930984e-01 0.159 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 6.930984e-01 0.159 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 6.999918e-01 0.155 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.045838e-01 0.152 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 7.045838e-01 0.152 0 0
Urea cycle R-HSA-70635 7.045838e-01 0.152 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 7.045838e-01 0.152 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 7.045838e-01 0.152 0 0
SLC transporter disorders R-HSA-5619102 7.061729e-01 0.151 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 7.120667e-01 0.147 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 7.156401e-01 0.145 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 7.156401e-01 0.145 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 7.156401e-01 0.145 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 7.156401e-01 0.145 0 0
Cristae formation R-HSA-8949613 7.156401e-01 0.145 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 7.156401e-01 0.145 0 0
Insulin processing R-HSA-264876 7.156401e-01 0.145 0 0
Maturation of hRSV A proteins R-HSA-9828806 7.156401e-01 0.145 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.156401e-01 0.145 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 7.158805e-01 0.145 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 7.203970e-01 0.142 0 0
Extension of Telomeres R-HSA-180786 7.235565e-01 0.141 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 7.235565e-01 0.141 0 0
tRNA processing R-HSA-72306 7.250318e-01 0.140 0 0
HIV elongation arrest and recovery R-HSA-167287 7.262832e-01 0.139 0 0
Pausing and recovery of HIV elongation R-HSA-167290 7.262832e-01 0.139 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.262832e-01 0.139 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 7.262832e-01 0.139 0 0
Pyroptosis R-HSA-5620971 7.262832e-01 0.139 0 0
Mitochondrial biogenesis R-HSA-1592230 7.342659e-01 0.134 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.365286e-01 0.133 0 0
Signaling by Erythropoietin R-HSA-9006335 7.365286e-01 0.133 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 7.396101e-01 0.131 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.463911e-01 0.127 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 7.463911e-01 0.127 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.463911e-01 0.127 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.463911e-01 0.127 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.463911e-01 0.127 0 0
FCGR activation R-HSA-2029481 7.510216e-01 0.124 0 0
Molecules associated with elastic fibres R-HSA-2129379 7.558850e-01 0.122 0 0
Aspartate and asparagine metabolism R-HSA-8963693 7.558850e-01 0.122 0 0
Keratinization R-HSA-6805567 7.565596e-01 0.121 0 0
DAG1 glycosylations R-HSA-8931838 7.650241e-01 0.116 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.650241e-01 0.116 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 7.650241e-01 0.116 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.650241e-01 0.116 0 0
Potential therapeutics for SARS R-HSA-9679191 7.658478e-01 0.116 0 0
Potassium Channels R-HSA-1296071 7.734048e-01 0.112 0 0
G-protein beta:gamma signalling R-HSA-397795 7.738215e-01 0.111 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.738215e-01 0.111 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 7.738215e-01 0.111 0 0
Cardiogenesis R-HSA-9733709 7.738215e-01 0.111 0 0
Recycling of bile acids and salts R-HSA-159418 7.738215e-01 0.111 0 0
FGFR1 mutant receptor activation R-HSA-1839124 7.738215e-01 0.111 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 7.746015e-01 0.111 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.822901e-01 0.107 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 7.840808e-01 0.106 0 0
eNOS activation R-HSA-203615 7.904421e-01 0.102 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 7.904421e-01 0.102 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 7.982894e-01 0.098 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 7.982894e-01 0.098 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 7.982894e-01 0.098 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 7.982894e-01 0.098 0 0
GPVI-mediated activation cascade R-HSA-114604 8.058432e-01 0.094 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 8.058432e-01 0.094 0 0
Triglyceride catabolism R-HSA-163560 8.058432e-01 0.094 0 0
RNA Polymerase III Transcription R-HSA-74158 8.058432e-01 0.094 0 0
Collagen chain trimerization R-HSA-8948216 8.131146e-01 0.090 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 8.190277e-01 0.087 0 0
Signaling by FGFR in disease R-HSA-1226099 8.190277e-01 0.087 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.201142e-01 0.086 0 0
Elastic fibre formation R-HSA-1566948 8.201142e-01 0.086 0 0
MET promotes cell motility R-HSA-8875878 8.201142e-01 0.086 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 8.242025e-01 0.084 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 8.242025e-01 0.084 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 8.268519e-01 0.083 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 8.268519e-01 0.083 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.268519e-01 0.083 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 8.268519e-01 0.083 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 8.333377e-01 0.079 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 8.333377e-01 0.079 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 8.333377e-01 0.079 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.333377e-01 0.079 0 0
HIV Transcription Elongation R-HSA-167169 8.333377e-01 0.079 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.333377e-01 0.079 0 0
Generation of second messenger molecules R-HSA-202433 8.333377e-01 0.079 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.333377e-01 0.079 0 0
Diseases of Immune System R-HSA-5260271 8.333377e-01 0.079 0 0
Tryptophan catabolism R-HSA-71240 8.333377e-01 0.079 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 8.333377e-01 0.079 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 8.395810e-01 0.076 0 0
Maturation of spike protein R-HSA-9694548 8.395810e-01 0.076 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 8.435958e-01 0.074 0 0
Intra-Golgi traffic R-HSA-6811438 8.455907e-01 0.073 0 0
G alpha (s) signalling events R-HSA-418555 8.487849e-01 0.071 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 8.513756e-01 0.070 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.513756e-01 0.070 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 8.569442e-01 0.067 0 0
Bacterial Infection Pathways R-HSA-9824439 8.577495e-01 0.067 0 0
Methylation R-HSA-156581 8.623044e-01 0.064 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 8.674641e-01 0.062 0 0
Peptide hormone metabolism R-HSA-2980736 8.752681e-01 0.058 0 0
Sulfur amino acid metabolism R-HSA-1614635 8.766663e-01 0.057 0 0
Gastrulation R-HSA-9758941 8.792392e-01 0.056 0 0
Co-stimulation by CD28 R-HSA-389356 8.818136e-01 0.055 0 0
Plasma lipoprotein remodeling R-HSA-8963899 8.818136e-01 0.055 0 0
NGF-stimulated transcription R-HSA-9031628 8.818136e-01 0.055 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 8.862433e-01 0.052 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.883394e-01 0.051 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.905073e-01 0.050 0 0
Neddylation R-HSA-8951664 8.962484e-01 0.048 0 0
Neurexins and neuroligins R-HSA-6794361 8.985625e-01 0.046 0 0
Paracetamol ADME R-HSA-9753281 9.095495e-01 0.041 0 0
Dectin-2 family R-HSA-5621480 9.162058e-01 0.038 0 0
IRS-mediated signalling R-HSA-112399 9.162058e-01 0.038 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.193482e-01 0.037 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.205087e-01 0.036 0 0
Triglyceride metabolism R-HSA-8979227 9.223729e-01 0.035 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.223729e-01 0.035 0 0
Metabolism of nucleotides R-HSA-15869 9.242628e-01 0.034 0 0
tRNA Aminoacylation R-HSA-379724 9.252844e-01 0.034 0 0
Regulation of PTEN gene transcription R-HSA-8943724 9.252844e-01 0.034 0 0
Metabolism of polyamines R-HSA-351202 9.252844e-01 0.034 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.280869e-01 0.032 0 0
Collagen degradation R-HSA-1442490 9.280869e-01 0.032 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.307844e-01 0.031 0 0
Complex I biogenesis R-HSA-6799198 9.333809e-01 0.030 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.358802e-01 0.029 0 0
IGF1R signaling cascade R-HSA-2428924 9.358802e-01 0.029 0 0
Insulin receptor signalling cascade R-HSA-74751 9.358802e-01 0.029 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.382858e-01 0.028 0 0
Respiratory electron transport R-HSA-611105 9.418976e-01 0.026 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.428301e-01 0.026 0 0
Metabolism of steroid hormones R-HSA-196071 9.428301e-01 0.026 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.437634e-01 0.025 0 0
Transcription of the HIV genome R-HSA-167172 9.449754e-01 0.025 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.463361e-01 0.024 0 0
Antimicrobial peptides R-HSA-6803157 9.480042e-01 0.023 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.490278e-01 0.023 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.496227e-01 0.022 0 0
Visual phototransduction R-HSA-2187338 9.502705e-01 0.022 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.509409e-01 0.022 0 0
Metabolism of cofactors R-HSA-8978934 9.509409e-01 0.022 0 0
GPCR downstream signalling R-HSA-388396 9.544547e-01 0.020 0 0
Aspirin ADME R-HSA-9749641 9.545546e-01 0.020 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.570202e-01 0.019 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.610042e-01 0.017 0 0
Interleukin-10 signaling R-HSA-6783783 9.624684e-01 0.017 0 0
Integrin cell surface interactions R-HSA-216083 9.624684e-01 0.017 0 0
G alpha (12/13) signalling events R-HSA-416482 9.624684e-01 0.017 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 9.624684e-01 0.017 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.638777e-01 0.016 0 0
Transport of small molecules R-HSA-382551 9.672456e-01 0.014 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.690060e-01 0.014 0 0
Protein-protein interactions at synapses R-HSA-6794362 9.712907e-01 0.013 0 0
Adipogenesis R-HSA-9843745 9.759441e-01 0.011 0 0
Neurotransmitter release cycle R-HSA-112310 9.771844e-01 0.010 0 0
Signaling by GPCR R-HSA-372790 9.788907e-01 0.009 0 0
Signaling by Insulin receptor R-HSA-74752 9.796613e-01 0.009 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.832073e-01 0.007 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.832073e-01 0.007 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.850312e-01 0.007 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.883666e-01 0.005 0 0
Drug ADME R-HSA-9748784 9.943073e-01 0.002 0 0
Diseases of metabolism R-HSA-5668914 9.951934e-01 0.002 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.959603e-01 0.002 0 0
Peptide ligand-binding receptors R-HSA-375276 9.965431e-01 0.002 0 0
Metabolism of steroids R-HSA-8957322 9.967476e-01 0.001 0 0
O-linked glycosylation R-HSA-5173105 9.972347e-01 0.001 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.983858e-01 0.001 0 0
PPARA activates gene expression R-HSA-1989781 9.986683e-01 0.001 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.987670e-01 0.001 0 0
Diseases of glycosylation R-HSA-3781865 9.995807e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999130e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999317e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.999518e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999894e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999940e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999956e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999981e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999999e-01 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways