TAO2

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 S939 Sugiyama POTEF A26C1B VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A5A3E0 T789 Sugiyama POTEF A26C1B YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPVLLTEAT
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
O00303 T119 Sugiyama EIF3F EIF3S5 LASIVDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPH
O00303 T123 Sugiyama EIF3F EIF3S5 VDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPHNEsE
O00488 S93 Sugiyama ZNF593 ZT86 STNLKTHFRSKDHKKRLKQLsVEPysQEEAERAAGMGSYVP
O14818 T147 Sugiyama PSMA7 HSPC FGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKS
O14818 T152 Sugiyama PSMA7 HSPC LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL
O14980 S450 Sugiyama XPO1 CRM1 VLVVENDQGEVVREFMKDTDsINLyKNMRETLVyLTHLDyV
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O43175 T353 Sugiyama PHGDH PGDH3 IGLAEALGTLMRAWAGSPKGtIQVITQGtsLKNAGNCLsPA
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43390 T141 Sugiyama HNRNPR HNRPR GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP
O43399 T173 Sugiyama TPD52L2 RKLGDMRNsAtFKsFEDRVGtIKSKVVGDRENGsDNLPssA
O43423 T101 Sugiyama ANP32CP PP32R1 EKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCEV
O43615 T106 Sugiyama TIMM44 MIMT44 TIM44 DEARRLEEsDVLQEARRKyKtIESETVRTSEVLRKKLGELT
O43615 Y104 Sugiyama TIMM44 MIMT44 TIM44 FRDEARRLEEsDVLQEARRKyKtIESETVRTSEVLRKKLGE
O43707 S507 Sugiyama ACTN4 DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID
O43707 S511 Sugiyama ACTN4 VNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAIDQLHL
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43715 S33 Sugiyama TRIAP1 15E1.1 HSPC132 REYDQCFNRWFAEKFLKGDssGDPCTDLFKRYQQCVQKAIK
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O60506 T138 Sugiyama SYNCRIP HNRPQ NSAP1 GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP
O60664 S225 Sugiyama PLIN3 M6PRBP1 TIP47 PLTDAELARIAtsLDGFDVAsVQQQRQEQSyFVRLGsLSER
O60664 T216 Sugiyama PLIN3 M6PRBP1 TIP47 sEEWADNHLPLTDAELARIAtsLDGFDVAsVQQQRQEQSyF
O60716 S230 Sugiyama CTNND1 KIAA0384 PDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRA
O75534 S584 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR YSLSKGKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRP
O75534 T761 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR GPKAVAAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDN
O75821 T240 Sugiyama EIF3G EIF3S4 DGAsRRGESMQPNRRADDNAtIRVtNLSEDTRETDLQELFR
O95071 T119 Sugiyama UBR5 EDD EDD1 HYD KIAA0896 GRTSRPGRTSDsPWFLsGSEtLGRLAGNTLGSRWSsGVGGs
O95373 T968 Sugiyama IPO7 RANBP7 IIDDEDNPVDEYQIFKAIFQtIQNRNPVWyQALTHGLNEEQ
O95626 T105 Sugiyama ANP32D PP32R2 EKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCEV
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00492 T124 Sugiyama HPRT1 HPRT sYCNDQsTGDIKVIGGDDLstLTGKNVLIVEDIIDTGKTMQ
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 T369 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV
P00558 T378 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02786 S151 Sugiyama TFRC LsEKLDstDFTGtIKLLNENsyVPREAGsQKDENLALyVEN
P02786 T143 Sugiyama TFRC yWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAGsQKDE
P04040 S515 Sugiyama CAT ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________
P04040 S517 Sugiyama CAT LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________
P04040 T115 Sugiyama CAT SKAKVFEHIGKKTPIAVRFStVAGEsGSADtVRDPRGFAVK
P04040 T125 Sugiyama CAT KKTPIAVRFStVAGEsGSADtVRDPRGFAVKFYTEDGNWDL
P04040 T434 Sugiyama CAT QQPSALEHSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEE
P04040 T441 Sugiyama CAT HSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEEQRKRLCE
P04040 T511 Sugiyama CAT SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____
P04075 S17 Sugiyama ALDOA ALDA ____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S356 Sugiyama ALDOA ALDA sLACQGKytPsGQAGAAAsEsLFVsNHAy____________
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075 T123 Sugiyama ALDOA ALDA GVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGA
P04075 T124 Sugiyama ALDOA ALDA VVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGAD
P04075 T49 Sugiyama ALDOA ALDA GILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDR
P04075 Y364 Sugiyama ALDOA ALDA tPsGQAGAAAsEsLFVsNHAy____________________
P04083 T169 Sugiyama ANXA1 ANX1 LPC1 IRDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRs
P04083 T223 Sugiyama ANXA1 ANX1 LPC1 ARALyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKY
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S151 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV
P04406 S210 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 T154 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEGL
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05388 S37 Sugiyama RPLP0 IIQLLDDyPKCFIVGADNVGsKQMQQIRMSLRGKAVVLMGK
P05388 T122 Sugiyama RPLP0 LLANKVPAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALG
P05388 T128 Sugiyama RPLP0 PAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALGItTKIS
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05783 S93 Sugiyama KRT18 CYK18 PIG46 GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR
P05783 T144 Sugiyama KRT18 CYK18 PIG46 RDWsHyFKIIEDLRAQIFANtVDNARIVLQIDNARLAADDF
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S291 Sugiyama KRT8 CYK8 ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06744 S247 Sugiyama GPI EWFLQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFW
P06744 T250 Sugiyama GPI LQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFWDWV
P06748 S260 Sugiyama NPM1 NPM GPssVEDIKAKMQAsIEKGGsLPKVEAKFINyVKNCFRMtD
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T18 Sugiyama LDHB ___MATLKEKLIAPVAEEEAtVPNNKITVVGVGQVGMACAI
P07195 T302 Sugiyama LDHB YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 S168 Sugiyama TUBB TUBB5 OK/SW-cl.56 GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07437 T166 Sugiyama TUBB TUBB5 OK/SW-cl.56 GMGTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
P07437 T55 Sugiyama TUBB TUBB5 OK/SW-cl.56 tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07737 S85 Sugiyama PFN1 tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 T1506 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 LCELQPGAKCVCGKNPAKyytLFGRsy______________
P07858 T218 Sugiyama CTSB CPSB CTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSEKD
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S391 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P07900 S476 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900 T109 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LtIVDtGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
P07900 T317 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07900 T467 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN
P08238 S383 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S482 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 T104 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LtLVDtGIGMtKADLINNLGtIAKSGtKAFMEALQAGADIS
P08238 T309 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 T479 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAF
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08238 T637 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL
P08238 T83 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sKLDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLG
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P08865 T94 Sugiyama RPSA LAMBR LAMR1 VsVIssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQA
P08865 T97 Sugiyama RPSA LAMBR LAMR1 IssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQAAFR
P09001 Y265 Sugiyama MRPL3 MRL3 RPML3 TGDIGRVWPGTKMPGKMGNIyRTEYGLKVWRINTKHNIIYV
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09661 S212 Sugiyama SNRPA1 KKGGPsPGDVEAIKNAIANAstLAEVERLKGLLQsGQIPGR
P09960 S486 Sugiyama LTA4H LTA4 TNACIALSQRWITAKEDDLNsFNAtDLKDLsSHQLNEFLAQ
P09972 T123 Sugiyama ALDOC ALDC IVVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGA
P09972 T125 Sugiyama ALDOC ALDC VGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGADF
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG38 T789 Sugiyama POTEI YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 T752 Sugiyama POTEJ YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7 T334 Sugiyama TUBA3C TUBA2 ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
P0DPH7 T337 Sugiyama TUBA3C TUBA2 MLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
P0DPH7 T51 Sugiyama TUBA3C TUBA2 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10809 S453 Sugiyama HSPD1 HSP60 EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P10809 S67 Sugiyama HSPD1 HSP60 LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK
P10809 T61 Sugiyama HSPD1 HSP60 LQGVDLLADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVA
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T37 Sugiyama HSPA8 HSC70 HSP73 HSPA10 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P11142 T38 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P11142 T427 Sugiyama HSPA8 HSC70 HSP73 HSPA10 GGVMTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGER
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P11940 T191 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 GRFKSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLF
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12277 T322 Sugiyama CKB CKBB LGKHEKFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRL
P12277 T327 Sugiyama CKB CKBB KFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRLGFSEV
P12814 T424 Sugiyama ACTN1 sIHEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEsDL
P12814 T426 Sugiyama ACTN1 HEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEsDLAA
P13489 S178 Sugiyama RNH1 PRI RNH SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13489 S290 Sugiyama RNH1 PRI RNH AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE
P13489 T176 Sugiyama RNH1 PRI RNH AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 T5 Sugiyama EEF2 EF2 ________________MVNFtVDQIRAIMDKKANIRNMsVI
P13639 T735 Sugiyama EEF2 EF2 HRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCPEQV
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667 S126 Sugiyama PDIA4 ERP70 ERP72 NILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILKKG
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13667 T123 Sugiyama PDIA4 ERP70 ERP72 KIANILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKIL
P13674 T140 Sugiyama P4HA1 P4HA YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13984 T16 Sugiyama GTF2F2 RAP30 _____MAERGELDLTGAKQNtGVWLVKVPKYLsQQWAKASG
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314 T115 Sugiyama PRKCSH G19P1 GVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQQMAEVtR
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14314 Y465 Sugiyama PRKCSH G19P1 sLGtWGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLC
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P15311 T533 Sugiyama EZR VIL2 NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15880 T230 Sugiyama RPS2 RPS4 PKKLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysy
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P16070 S71 Sugiyama CD44 LHR MDU2 MDU3 MIC4 DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI
P16070 T76 Sugiyama CD44 LHR MDU2 MDU3 MIC4 FNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRIHPNSI
P16083 S80 Sugiyama NQO2 NMOR2 LSNPEVFNyGVEtHEAyKQRsLAsDITDEQKKVREADLVIF
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17066 T224 Sugiyama HSPA6 HSP70B' GGTFDVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFM
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17066 Y43 Sugiyama HSPA6 HSP70B' FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P17174 S106 Sugiyama GOT1 RLALGDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNG
P17174 T110 Sugiyama GOT1 GDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNGTNNK
P17987 S544 Sugiyama TCP1 CCT1 CCTA ILRIDDLIKLHPESKDDKHGsyEDAVHsGALND________
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 T452 Sugiyama NCL AyIEFKTEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQD
P19419 S383 SIGNOR|iPTMNet|EPSD ELK1 tPVLLtPSSLPPSIHFWSTLsPIAPRsPAKLSFQFPSSGSA
P22090 S204 Sugiyama RPS4Y1 RPS4Y PRO2646 IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22626 T176 Sugiyama HNRNPA2B1 HNRPA2B1 GFVtFDDHDPVDKIVLQKyHtINGHNAEVRKALsRQEMQEV
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P24752 T220 Sugiyama ACAT1 ACAT MAT TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV
P25705 S198 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK
P25786 T11 Sugiyama PSMA1 HC2 NU PROS30 PSC2 __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ
P25788 S243 Sugiyama PSMA3 HC8 PSC8 GRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM________
P25788 Y239 Sugiyama PSMA3 HC8 PSC8 ELTNGRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM____
P25789 S7 Sugiyama PSMA4 HC9 PSC9 ______________MSRRyDsRttIFsPEGRLYQVEYAMEA
P25789 T10 Sugiyama PSMA4 HC9 PSC9 ___________MSRRyDsRttIFsPEGRLYQVEYAMEAIGH
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26373 S109 Sugiyama RPL13 BBC1 OK/SW-cl.46 KVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILFPR
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26373 T24 Sugiyama RPL13 BBC1 OK/SW-cl.46 SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR
P26639 S522 Sugiyama TARS1 TARS PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP
P26639 T250 Sugiyama TARS1 TARS FKYNKFKCRILNEKVNtPtttVyRCGPLIDLCRGPHVRHTG
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P28066 T14 Sugiyama PSMA5 _______MFLTRsEyDRGVNtFsPEGRLFQVEyAIEAIKLG
P28066 T161 Sugiyama PSMA5 LLFGGVDEKGPQLFHMDPsGtFVQCDARAIGsAsEGAQssL
P29401 S305 Sugiyama TKT LAtPPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQAL
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29401 T454 Sugiyama TKT LAMFRsVPtstVFyPsDGVAtEKAVELAANTKGICFIRTsR
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 T147 Sugiyama EEF1D EF1D PQtQHVsPMRQVEPPAKKPAtPAEDDEDDDIDLFGsDNEEE
P30041 T48 Sugiyama PRDX6 AOP2 KIAA0106 FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL
P30048 S199 Sugiyama PRDX3 AOP1 SGLALRGLFIIDPNGVIKHLsVNDLPVGRSVEETLRLVKAF
P30050 T25 Sugiyama RPL12 FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30101 T485 Sugiyama PDIA3 ERP57 ERP60 GRP58 KKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKKKAQEDL
P31327 S898 Sugiyama CPS1 LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31327 T45 Sugiyama CPS1 AHQKWKFSRPGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPS
P31327 T903 Sugiyama CPS1 DILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKCLGL
P31942 S298 Sugiyama HNRNPH3 HNRPH3 GGsGMGGYGRDGMDNQGGyGsVGRMGMGNNysGGyGtPDGL
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948 T243 Sugiyama STIP1 KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT
P31949 T33 Sugiyama S100A11 MLN70 S100C CIESLIAVFQKYAGKDGyNytLsKtEFLsFMNTELAAFTKN
P32119 T142 Sugiyama PRDX2 NKEFB TDPX1 EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931 T224 Sugiyama HSPA1L GGTFDVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFV
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931 T39 Sugiyama HSPA1L CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P34931 T40 Sugiyama HSPA1L VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932 T758 Sugiyama HSPA4 APG2 HSPH2 TNEAMEWMNNKLNLQNKQsLtMDPVVKSKEIEAKIKELTst
P35268 T62 Sugiyama RPL22 FLQERIKVNGKAGNLGGGVVtIERsKSKITVTSEVPFSKRY
P35269 T41 Sugiyama GTF2F1 RAP74 NTTKKyNIMAFNAADKVNFAtWNQARLERDLSNKKIyQEEE
P35579 S1916 Sugiyama MYH9 LQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMAR
P35579 T1906 Sugiyama MYH9 AQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRGDL
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36578 T23 Sugiyama RPL4 RPL1 CARPLISVysEKGESSGKNVtLPAVFKAPIRPDIVNFVHTN
P36871 S483 Sugiyama PGM1 DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37108 T45 Sugiyama SRP14 sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 S59 Sugiyama RPS19 LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019 T36 Sugiyama RPS19 RALAAFLKKSGKLKVPEWVDtVKLAKHKELAPyDENWFytR
P39019 T55 Sugiyama RPS19 DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019 T60 Sugiyama RPS19 AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P39687 T105 Sugiyama ANP32A C15orf1 LANP MAPM PHAP1 EKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCEV
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P40925 T225 Sugiyama MDH1 MDHA KEVGVyEALKDDsWLKGEFVttVQQRGAAVIKARKLssAMS
P40925 T226 Sugiyama MDH1 MDHA EVGVyEALKDDsWLKGEFVttVQQRGAAVIKARKLssAMSA
P40939 T393 Sugiyama HADHA HADH GAGIAQVSVDKGLKTILKDAtLtALDRGQQQVFKGLNDKVK
P41091 T21 Sugiyama EIF2S3 EIF2G MAGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAt
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42677 T74 Sugiyama RPS27 MPS1 VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
P43121 T100 Sugiyama MCAM MUC18 QGQSEPGEYEQRLsLQDRGAtLALtQVtPQDERIFLCQGKR
P43121 T104 Sugiyama MCAM MUC18 EPGEYEQRLsLQDRGAtLALtQVtPQDERIFLCQGKRPRSQ
P46060 S24 Sugiyama RANGAP1 KIAA1835 SD EDIAKLAETLAKTQVAGGQLsFKGKSLKLNTAEDAKDVIKE
P46734 S218 SIGNOR MAP2K3 MEK3 MKK3 PRKMK3 SKK2 INKEGHVKMCDFGISGyLVDsVAKtMDAGCKPYMAPERINP
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46776 T95 Sugiyama RPL27A LDKLWtLVsEQtRVNAAKNKtGAAPIIDVVRsGyyKVLGKG
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P47756 T186 Sugiyama CAPZB HYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDC
P48637 S276 Sugiyama GSS VDGQEIAVVYFRDGYMPRQYsLQNWEARLLLERSHAAKCPD
P48643 S270 Sugiyama CCT5 CCTE KIAA0098 ILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQ
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P48741 T224 Sugiyama HSPA7 HSP70B GGTFDVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFM
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P48741 Y43 Sugiyama HSPA7 HSP70B FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P49327 T1999 Sugiyama FASN FAS LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF
P49327 T2215 Sugiyama FASN FAS DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49368 T373 Sugiyama CCT3 CCTG TRIC5 KKIGDEYFTFITDCKDPKACtILLRGAsKEILSEVERNLQD
P49368 T430 Sugiyama CCT3 CCTG TRIC5 GGGASEMAVAHALTEKSKAMtGVEQWPyRAVAQALEVIPRT
P49368 T459 Sugiyama CCT3 CCTG TRIC5 AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG
P49411 T433 Sugiyama TUFM LRQPMILEKGQRFTLRDGNRtIGTGLVTNTLAMTEEEKNIK
P49773 T17 Sugiyama HINT1 HINT PKCI1 PRKCNH1 ____MADEIAKAQVARPGGDtIFGKIIRKEIPAKIIFEDDR
P50395 T205 Sugiyama GDI2 RABGDIB TGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsPYL
P50990 T374 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDD
P50990 T398 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 RGstDNLMDDIERAVDDGVNtFKVLTRDKRLVPGGGAtEIE
P50991 T69 Sugiyama CCT4 CCTD SRB RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR
P51149 T168 Sugiyama RAB7A RAB7 NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE
P52564 S207 SIGNOR MAP2K6 MEK6 MKK6 PRKMK6 SKK3 INALGQVKMCDFGISGyLVDsVAKtIDAGCKPyMAPERINP
P52948 S679 Sugiyama NUP98 ADAR2 ytNPIAKPIPQtPEsAGNKHsNsNsVDDtIVALNMRAALRN
P52948 S681 Sugiyama NUP98 ADAR2 NPIAKPIPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGL
P52948 T687 Sugiyama NUP98 ADAR2 IPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEGssEE
P53621 T821 Sugiyama COPA IMPLDTNWPLLTVSKGFFEGtIAsKGKGGALAADIDIDTVG
P54577 T130 Sugiyama YARS1 YARS VPLEKLKFIKGTDYQLSKEytLDVyRLSSVVTQHDSKKAGA
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T38 Sugiyama HSPA2 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P54652 T39 Sugiyama HSPA2 VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55010 T227 Sugiyama EIF5 ttEEAQRRRMDEISDHAKVLtLsDDLERtIEERVNILFDFV
P55036 S358 Sugiyama PSMD4 MCB1 VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_
P55854 S27 Sugiyama SUMO3 SMT3A SMT3H1 KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P57721 S59 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT EGGLNVTLTIRLLMHGKEVGsIIGKKGETVKKMREESGARI
P57723 S31 Sugiyama PCBP4 EPELSITLTLRMLMHGKEVGsIIGKKGETVKRIREQSSARI
P60174 S195 Sugiyama TPI1 TPI KtATPQQAQEVHEKLRGWLKsNVsDAVAQstRIIyGGsVtG
P60174 S204 Sugiyama TPI1 TPI EVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQ
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T176 Sugiyama TPI1 TPI KDWSKVVLAyEPVWAIGtGKtATPQQAQEVHEKLRGWLKsN
P60174 T205 Sugiyama TPI1 TPI VHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQP
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T28 Sugiyama TPI1 TPI FVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVVCAPPtAy
P60174 T90 Sugiyama TPI1 TPI VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI
P60174 Y209 Sugiyama TPI1 TPI LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 T22 Sugiyama MYL6 CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN
P60660 T85 Sugiyama MYL6 LDFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVM
P60660 Y86 Sugiyama MYL6 DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S239 Sugiyama ACTB VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T202 Sugiyama ACTB GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709 T203 Sugiyama ACTB RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T297 Sugiyama ACTB TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709 T303 Sugiyama ACTB MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P60709 T304 Sugiyama ACTB KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 T89 Sugiyama ACTB YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP
P60709 Y198 Sugiyama ACTB LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y306 Sugiyama ACTB DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P61158 S406 Sugiyama ACTR3 ARP3 STPEFYQVCHTKKDyEEIGPsICRHNPVFGVMs________
P61204 S147 Sugiyama ARF3 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61587 S210 PSP RND3 ARHE RHO8 RHOE FHVATLACVNKTNKNVKRNKsQRATKRIsHMPSRPELSAVA
P61587 S218 PSP RND3 ARHE RHO8 RHOE VNKTNKNVKRNKsQRATKRIsHMPSRPELSAVATDLRKDKA
P61587 S240 PSP RND3 ARHE RHO8 RHOE MPSRPELSAVATDLRKDKAKsCTVM________________
P61916 S29 Sugiyama NPC2 HE1 LLLALSTAAQAEPVQFKDCGsVDGVIKEVNVsPCPtQPCQL
P61956 S28 Sugiyama SUMO2 SMT3B SMT3H2 EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981 T31 Sugiyama YWHAG ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62273 S9 Sugiyama RPS29 ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T15 Sugiyama RPS11 ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62316 T40 Sugiyama SNRPD2 SNRPD1 EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62424 T84 Sugiyama RPL7A SURF-3 SURF3 QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP
P62701 S204 Sugiyama RPS4X CCG2 RPS4 SCAR tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62736 S241 Sugiyama ACTA2 ACTSA ACTVS GIG46 VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62826 S150 Sugiyama RAN ARA24 OK/SW-cl.81 KVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARKLIG
P62826 T21 Sugiyama RAN ARA24 OK/SW-cl.81 MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 T157 Sugiyama PPIA CYPA NIVEAMERFGsRNGKTSKKItIADCGQLE____________
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 T147 Sugiyama RPS27A UBA80 UBCEP1 GAGVFMAsHFDRHyCGKCCLtyCFNKPEDK___________
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63104 T30 Sugiyama YWHAZ AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S239 Sugiyama ACTG1 ACTG VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T202 Sugiyama ACTG1 ACTG GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261 T203 Sugiyama ACTG1 ACTG RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T297 Sugiyama ACTG1 ACTG TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261 T303 Sugiyama ACTG1 ACTG MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P63261 T304 Sugiyama ACTG1 ACTG KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 T89 Sugiyama ACTG1 ACTG YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP
P63261 Y198 Sugiyama ACTG1 ACTG LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y306 Sugiyama ACTG1 ACTG DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S240 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68032 S241 Sugiyama ACTC1 ACTC VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 T91 Sugiyama ACTC1 ACTC yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S241 Sugiyama ACTA1 ACTA VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 T91 Sugiyama ACTA1 ACTA yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 S439 Sugiyama TUBA1B SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 T334 Sugiyama TUBA1B ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG
P68363 T337 Sugiyama TUBA1B LLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVGINy
P68363 T51 Sugiyama TUBA1B QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371 T246 Sugiyama CCT2 99D8.1 CCTB VNQPKRIENAKILIANtGMDtDKIKIFGsRVRVDstAKVAE
P78371 T64 Sugiyama CCT2 99D8.1 CCTB GPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVL
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P78417 S23 Sugiyama GSTO1 GSTTLP28 GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S7 Sugiyama RPL24 ______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731 T52 Sugiyama RPL24 LNAKCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRT
P84077 S147 Sugiyama ARF1 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P99999 T50 Sugiyama CYCS CYC GPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEYLE
Q00341 T729 Sugiyama HDLBP HBP VGL VEKAKKQLLHLAEEKQTKSFtVDIRAKPEYHKFLIGKGGGK
Q00839 T530 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KTTWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtG
Q00839 T532 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 TWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtGKL
Q01105 S166 Sugiyama SET yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q02543 T101 Sugiyama RPL18A WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02878 T213 Sugiyama RPL6 TXREB1 FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06830 S152 Sugiyama PRDX1 PAGA PAGB TDPX2 IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV
Q06830 T143 Sugiyama PRDX1 PAGA PAGB TDPX2 EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF
Q06830 T156 Sugiyama PRDX1 PAGA PAGB TDPX2 KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020 T42 Sugiyama RPL18 DIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRPPLs
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q12792 T174 Sugiyama TWF1 PTK9 LRQIKINEVQtDVGVDTKHQtLQGVAFPISREAFQALEKLN
Q12906 T300 Sugiyama ILF3 DRBF MPHOSPH4 NF90 ASGIVMPDGSGIYDPCEKEAtDAIGHLDRQQREDItQsAQH
Q13263 S784 Sugiyama TRIM28 KAP1 RNF96 TIF1B DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK
Q13310 T191 Sugiyama PABPC4 APP1 PABP4 GRFKSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELF
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 S168 Sugiyama TUBB3 TUBB4 GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13509 T166 Sugiyama TUBB3 TUBB4 GMGTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13561 T315 Sugiyama DCTN2 DCTN50 KHKASVEDADTQSKVHQLyEtIQRWsPIASTLPELVQRLVT
Q13573 T261 Sugiyama SNW1 SKIIP SKIP EQQEWKIPPCISNWKNAKGytIPLDKRLAADGRGLQTVHIN
Q13765 T119 Sugiyama NACA HSD48 SKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAA
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S988 Sugiyama EIF3A EIF3S10 KIAA0139 PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN
Q14247 S113 Sugiyama CTTN EMS1 DRMDKsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVD
Q14444 T103 Sugiyama CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 NKGERLNQDQLDAVsKyQEVtNNLEFAKELQRsFMALsQDI
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14568 T109 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LTIVDTGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
Q14677 S164 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 RLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKW
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14974 T860 Sugiyama KPNB1 NTF97 RPMIHELLTEGRRSKTNKAKtLAtWATKELRKLKNQA____
Q14974 T863 Sugiyama KPNB1 NTF97 IHELLTEGRRSKTNKAKtLAtWATKELRKLKNQA_______
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15056 T100 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 KFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRK
Q15084 S169 Sugiyama PDIA6 ERP5 P5 TXNDC7 GKQGRSDsSSKKDVIELtDDsFDKNVLDSEDVWMVEFYAPW
Q15084 T100 Sugiyama PDIA6 ERP5 P5 TXNDC7 AVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPEDYQGGRTG
Q15084 Y93 Sugiyama PDIA6 ERP5 P5 TXNDC7 KDVVKVGAVDADKHHsLGGQyGVQGFPtIKIFGSNKNRPED
Q15185 S72 Sugiyama PTGES3 P23 TEBP EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15185 S85 Sugiyama PTGES3 P23 TEBP KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN
Q15293 S159 Sugiyama RCN1 RCN EyKQAtyGyyLGNPAEFHDssDHHtFKKMLPRDERRFKAAD
Q15293 S69 Sugiyama RCN1 RCN PPEDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVD
Q15293 T163 Sugiyama RCN1 RCN AtyGyyLGNPAEFHDssDHHtFKKMLPRDERRFKAADLNGD
Q15293 T71 Sugiyama RCN1 RCN EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI
Q15293 Y145 Sugiyama RCN1 RCN KDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFK
Q15293 Y148 Sugiyama RCN1 RCN DRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFKKML
Q15365 S27 Sugiyama PCBP1 ESGLNVTLTIRLLMHGKEVGsIIGKKGESVKRIREEsGARI
Q15366 S27 Sugiyama PCBP2 EGGLNVTLTIRLLMHGKEVGsIIGKKGESVKKMREESGARI
Q16181 T426 PSP SEPTIN7 CDC10 SEPT7 DEKANWEAQQRILEQQNssRtLEKNKKKGKIF_________
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16775 T292 Sugiyama HAGH GLO2 HAGH1 FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____
Q27J81 T1206 Sugiyama INF2 C14orf151 C14orf173 DtsLDKsFsEDAVtDssGsGtLPRARGRASKGTGKRRKKRP
Q2VIR3 T21 Sugiyama EIF2S3B MAGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAt
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3ZCM7 S75 Sugiyama TUBB8 SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC
Q3ZCM7 T72 Sugiyama TUBB8 NEASGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIF
Q562R1 S240 Sugiyama ACTBL2 VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q58FF8 T104 Sugiyama HSP90AB2P HSP90BB LTLVDTGIGMTKADLINNLGtIAKFQDQTEYLEEMQVKEVV
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6EEV6 S28 Sugiyama SUMO4 SMT3H4 EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2 T334 Sugiyama TUBA3E ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q6PEY2 T337 Sugiyama TUBA3E MLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
Q6PEY2 T51 Sugiyama TUBA3E QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 S939 Sugiyama POTEE A26C1A POTE2 VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6S8J3 T789 Sugiyama POTEE A26C1A POTE2 YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71U36 S439 Sugiyama TUBA1A TUBA3 SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 T334 Sugiyama TUBA1A TUBA3 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q71U36 T337 Sugiyama TUBA1A TUBA3 LLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
Q71U36 T51 Sugiyama TUBA1A TUBA3 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q71UM5 T74 Sugiyama RPS27L VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
Q7L7X3 S38 Sugiyama TAOK1 KIAA1361 MAP3K16 MARKK LFFKEDPEKLFTDLREIGHGsFGAVyFARDVRTNEVVAIKK
Q7L7X3 Y43 Sugiyama TAOK1 KIAA1361 MAP3K16 MARKK DPEKLFTDLREIGHGsFGAVyFARDVRTNEVVAIKKMSYSG
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86VQ1 S223 Sugiyama GLCCI1 QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR
Q86W56 Y832 Sugiyama PARG DDWQRRCTEIVAIDALHFRRyLDQFVPEKMRRELNKAYCGF
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8NBJ7 S256 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG
Q8NHW5 S37 Sugiyama RPLP0P6 IIQLLDDyPKCFIVGADNVGsKQMQQIRMSLRGKVVVLMGK
Q8NHW5 T122 Sugiyama RPLP0P6 LLANKVPAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALG
Q8NHW5 T128 Sugiyama RPLP0P6 PAAARAGAIAPCEVtVPAQNtGLGPEKTSFFQALGItTKIS
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TF09 T67 Sugiyama DYNLRB2 DNCL2B DNLC2B ROBLD2 HHLTMKAKSTVRDIDPQNDLtFLRIRSKKHEIMVAPDKEYL
Q8WXX5 S215 Sugiyama DNAJC9 EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL
Q96AY3 T200 Sugiyama FKBP10 FKBP65 PSEC0056 HYNGTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLG
Q96AY3 T203 Sugiyama FKBP10 FKBP65 PSEC0056 GTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGMCP
Q96HE7 S143 Sugiyama ERO1A ERO1L UNQ434/PRO865 EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q96HE7 T148 Sugiyama ERO1A ERO1L UNQ434/PRO865 IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA
Q96ST3 S158 Sugiyama SIN3A GSQPQVYNDFLDIMKEFKSQsIDtPGVISRVSQLFKGHPDL
Q99547 T124 Sugiyama MPHOSPH6 MPP6 TVELDVsDEEMARRyEtLVGtIGKKFARKRDHANYEEDENG
Q99547 Y118 Sugiyama MPHOSPH6 MPP6 EEVEDETVELDVsDEEMARRyEtLVGtIGKKFARKRDHANY
Q99575 S129 Sugiyama POP1 KIAA0061 QARAAEISAMLKAVTQKssNsLVFQtLPRHMRRRAMSHNVK
Q99575 T134 Sugiyama POP1 KIAA0061 EISAMLKAVTQKssNsLVFQtLPRHMRRRAMSHNVKRLPRR
Q99584 S62 Sugiyama S100A13 VTQQLPHLLKDVGSLDEKMKsLDVNQDSELKFNEyWRLIGE
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99613 T880 Sugiyama EIF3C EIF3S8 AEKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMR
Q99733 T24 Sugiyama NAP1L4 NAP2 HsFsDGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQER
Q99733 T28 Sugiyama NAP1L4 NAP2 DGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQERLDNV
Q99832 S59 Sugiyama CCT7 CCTH NIP7-1 TLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTL
Q99832 T371 Sugiyama CCT7 CCTH NIP7-1 tQIGGERyNFFtGCPKAKTCtFILRGGAEQFMEEtERSLHD
Q99832 T64 Sugiyama CCT7 CCTH NIP7-1 GMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTLVDIAK
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3 T334 Sugiyama TUBA1C TUBA6 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q9BQE3 T337 Sugiyama TUBA1C TUBA6 LLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
Q9BQE3 T51 Sugiyama TUBA1C TUBA6 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BS26 T155 Sugiyama ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 yIRQQKSDPIQEIRDLAEIttLDRSKRNIIGYFEQKDSDNy
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BYX7 S239 Sugiyama POTEKP ACTBL3 FKSG30 VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 T89 Sugiyama POTEKP ACTBL3 FKSG30 YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9H0C2 S286 Sugiyama SLC25A31 AAC4 ANT4 SFEC DCFVKIYQHEGISSFFRGAFsNVLRGTGGALVLVLYDKIKE
Q9H2K8 S331 Sugiyama TAOK3 DPK JIK KDS MAP3K18 ILFQETRNGPLNEsQEDEEDsEHGTsLNREMDSLGSNHSIP
Q9H2K8 T592 Sugiyama TAOK3 DPK JIK KDS MAP3K18 stPKKEKQERISKHKENLQHtQAEEEAHLLtQQRLYYDKNC
Q9H2K8 T602 Sugiyama TAOK3 DPK JIK KDS MAP3K18 ISKHKENLQHtQAEEEAHLLtQQRLYYDKNCRFFKRKIMIK
Q9H2K8 T681 Sugiyama TAOK3 DPK JIK KDS MAP3K18 YRQLHTLQKLRMDLIRLQHQtELENQLEYNKRRERELHRKH
Q9NP97 T67 Sugiyama DYNLRB1 BITH DNCL2A DNLC2A ROBLD1 HSPC162 HSFILKARStVRDIDPQNDLtFLRIRsKKNEIMVAPDKDYF
Q9NPA8 S100 Sugiyama ENY2 DC6 PDSVKKELLQRIRTFLAQHAsL___________________
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UGV2 S327 Sugiyama NDRG3 KYFLQGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsV
Q9UGV2 S334 Sugiyama NDRG3 GYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsDG
Q9UGV2 S335 Sugiyama NDRG3 YIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsDGt
Q9UGV2 T329 Sugiyama NDRG3 FLQGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVts
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UL54 S181 PSP TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431 EPGLVKLGDFGSASIMAPANsFVGtPYWMAPEVILAMDEGQ
Q9UL54 S38 Sugiyama TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431 LFFKDDPEKLFSDLREIGHGsFGAVyFARDVRNSEVVAIKK
Q9UL54 Y43 Sugiyama TAOK2 KIAA0881 MAP3K17 PSK PSK1 UNQ2971/PRO7431 DPEKLFSDLREIGHGsFGAVyFARDVRNSEVVAIKKMSYSG
Q9UQ35 S2692 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2B0 T100 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL
Q9Y2B0 T132 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF
Q9Y3F4 S228 Sugiyama STRAP MAWD UNRIP FHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLy
Q9Y3F4 S230 Sugiyama STRAP MAWD UNRIP SAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLyKy
Q9Y3F4 T225 Sugiyama STRAP MAWD UNRIP SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF
Q9Y3F4 T48 Sugiyama STRAP MAWD UNRIP YGYFLISACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLN
Q9Y3F4 T54 Sugiyama STRAP MAWD UNRIP SACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLNKDATKA
Q9Y4L1 S461 Sugiyama HYOU1 GRP170 HSPH4 ORP150 VVYPILVEFTREVEEEPGIHsLKHNKRVLFSRMGPYPQRKV
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Cellular Senescence R-HSA-2559583 1.110223e-16 15.955 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 7.105427e-14 13.148 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.255485e-11 10.487 0 0
Diseases of programmed cell death R-HSA-9645723 1.245113e-10 9.905 0 0
Signal Transduction R-HSA-162582 1.263013e-10 9.899 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 5.767840e-10 9.239 0 0
Cell junction organization R-HSA-446728 7.492578e-10 9.125 0 0
Cell-Cell communication R-HSA-1500931 2.201939e-09 8.657 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 4.488308e-09 8.348 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 4.174386e-09 8.379 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 5.916080e-09 8.228 0 0
DNA methylation R-HSA-5334118 8.291378e-09 8.081 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 9.797116e-09 8.009 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.142591e-08 7.942 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.215761e-08 7.915 0 0
Defective pyroptosis R-HSA-9710421 1.304320e-08 7.885 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.286945e-08 7.890 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.390262e-08 7.857 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.896749e-08 7.722 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.730082e-08 7.564 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 2.892554e-08 7.539 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 3.205845e-08 7.494 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 3.389719e-08 7.470 0 0
Packaging Of Telomere Ends R-HSA-171306 3.879880e-08 7.411 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 4.375658e-08 7.359 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 4.352382e-08 7.361 0 0
Meiosis R-HSA-1500620 5.087920e-08 7.293 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 5.122723e-08 7.290 0 0
Mitotic Prophase R-HSA-68875 4.768180e-08 7.322 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 4.414032e-08 7.355 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.091794e-08 7.293 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.091794e-08 7.293 0 0
DNA Double Strand Break Response R-HSA-5693606 6.018488e-08 7.221 0 0
Oncogene Induced Senescence R-HSA-2559585 6.737378e-08 7.172 0 0
Cell-cell junction organization R-HSA-421270 6.922766e-08 7.160 0 0
Meiotic recombination R-HSA-912446 8.455929e-08 7.073 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.045875e-07 6.981 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.140312e-07 6.943 0 0
Meiotic synapsis R-HSA-1221632 1.288223e-07 6.890 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.478109e-07 6.830 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.734385e-07 6.761 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 2.120400e-07 6.674 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.077391e-07 6.682 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 3.130858e-07 6.504 0 0
Adherens junctions interactions R-HSA-418990 3.691742e-07 6.433 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 3.839282e-07 6.416 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.983988e-07 6.302 0 0
Cell Cycle R-HSA-1640170 5.901528e-07 6.229 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 6.354428e-07 6.197 0 0
Cell Cycle, Mitotic R-HSA-69278 7.210060e-07 6.142 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 7.514317e-07 6.124 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 7.360583e-07 6.133 0 0
Cleavage of the damaged purine R-HSA-110331 7.969171e-07 6.099 0 0
Depurination R-HSA-73927 1.003656e-06 5.998 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.025180e-06 5.989 0 0
Axon guidance R-HSA-422475 1.243418e-06 5.905 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.391841e-06 5.856 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.692235e-06 5.772 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.786023e-06 5.748 0 0
RNA Polymerase I Transcription R-HSA-73864 1.873892e-06 5.727 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.611316e-06 5.583 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 2.924193e-06 5.534 0 0
Depyrimidination R-HSA-73928 2.924193e-06 5.534 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 3.061178e-06 5.514 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.246817e-06 5.489 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 3.622285e-06 5.441 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.975022e-06 5.401 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 5.235106e-06 5.281 0 0
Nucleosome assembly R-HSA-774815 5.235106e-06 5.281 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 5.440114e-06 5.264 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 5.440114e-06 5.264 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 5.440114e-06 5.264 0 0
HDACs deacetylate histones R-HSA-3214815 5.757085e-06 5.240 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 5.793857e-06 5.237 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 6.006900e-06 5.221 0 0
Ub-specific processing proteases R-HSA-5689880 6.109363e-06 5.214 0 0
Co-inhibition by PD-1 R-HSA-389948 6.235686e-06 5.205 0 0
Apoptotic execution phase R-HSA-75153 6.301324e-06 5.201 0 0
G2/M Checkpoints R-HSA-69481 6.671683e-06 5.176 0 0
Nervous system development R-HSA-9675108 7.078630e-06 5.150 0 0
Gene Silencing by RNA R-HSA-211000 7.451743e-06 5.128 0 0
Cellular responses to stress R-HSA-2262752 8.018627e-06 5.096 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 8.857745e-06 5.053 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.083391e-05 4.965 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.233974e-05 4.909 0 0
Amyloid fiber formation R-HSA-977225 1.233974e-05 4.909 0 0
ESR-mediated signaling R-HSA-8939211 1.315076e-05 4.881 0 0
Cellular responses to stimuli R-HSA-8953897 1.414198e-05 4.849 0 0
Cell Cycle Checkpoints R-HSA-69620 2.032925e-05 4.692 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.142317e-05 4.669 0 0
L1CAM interactions R-HSA-373760 2.366177e-05 4.626 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 2.422695e-05 4.616 0 0
Interleukin-12 signaling R-HSA-9020591 2.685497e-05 4.571 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.940018e-05 4.532 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.116089e-05 4.506 0 0
Reproduction R-HSA-1474165 3.253658e-05 4.488 0 0
Base Excision Repair R-HSA-73884 4.114011e-05 4.386 0 0
Signaling by NOTCH R-HSA-157118 4.185252e-05 4.378 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 4.402320e-05 4.356 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 5.148460e-05 4.288 0 0
M Phase R-HSA-68886 5.455473e-05 4.263 0 0
Signaling by VEGF R-HSA-194138 6.046185e-05 4.219 0 0
Signaling by Hippo R-HSA-2028269 6.129569e-05 4.213 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 6.240663e-05 4.205 0 0
Assembly of the pre-replicative complex R-HSA-68867 6.369411e-05 4.196 0 0
Activation of HOX genes during differentiation R-HSA-5619507 6.888136e-05 4.162 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 6.888136e-05 4.162 0 0
Sema4D in semaphorin signaling R-HSA-400685 7.917024e-05 4.101 0 0
Homology Directed Repair R-HSA-5693538 9.397891e-05 4.027 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 9.821253e-05 4.008 0 0
Telomere Maintenance R-HSA-157579 1.065927e-04 3.972 0 0
Interleukin-12 family signaling R-HSA-447115 1.089044e-04 3.963 0 0
Chromosome Maintenance R-HSA-73886 1.223448e-04 3.912 0 0
HATs acetylate histones R-HSA-3214847 1.297829e-04 3.887 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.388901e-04 3.857 0 0
Apoptosis R-HSA-109581 1.691812e-04 3.772 0 0
Programmed Cell Death R-HSA-5357801 1.888519e-04 3.724 0 0
EPH-Ephrin signaling R-HSA-2682334 2.013373e-04 3.696 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.308452e-04 3.637 0 0
Deubiquitination R-HSA-5688426 2.472544e-04 3.607 0 0
TCF dependent signaling in response to WNT R-HSA-201681 2.837093e-04 3.547 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 3.093003e-04 3.510 0 0
DNA Replication Pre-Initiation R-HSA-69002 3.524712e-04 3.453 0 0
Signaling by WNT R-HSA-195721 4.447427e-04 3.352 0 0
MAPK family signaling cascades R-HSA-5683057 4.486391e-04 3.348 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.564721e-04 3.341 0 0
Signaling by Interleukins R-HSA-449147 5.055057e-04 3.296 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 5.321789e-04 3.274 0 0
Regulation of endogenous retroelements R-HSA-9842860 5.501783e-04 3.259 0 0
RAF/MAP kinase cascade R-HSA-5673001 6.246822e-04 3.204 0 0
DNA Replication R-HSA-69306 6.514608e-04 3.186 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 6.972811e-04 3.157 0 0
HCMV Late Events R-HSA-9610379 8.439129e-04 3.074 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 8.651096e-04 3.063 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 8.906307e-04 3.050 0 0
Chromatin organization R-HSA-4839726 9.272316e-04 3.033 0 0
Oncogenic MAPK signaling R-HSA-6802957 9.479027e-04 3.023 0 0
Chromatin modifying enzymes R-HSA-3247509 9.695246e-04 3.013 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 9.813501e-04 3.008 0 0
MECP2 regulates transcription factors R-HSA-9022707 1.041003e-03 2.983 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.080827e-03 2.966 0 0
Developmental Biology R-HSA-1266738 1.285762e-03 2.891 0 0
Semaphorin interactions R-HSA-373755 1.301723e-03 2.885 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.314794e-03 2.881 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.473178e-03 2.832 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.364504e-03 2.865 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.465510e-03 2.834 0 0
DNA Repair R-HSA-73894 1.550604e-03 2.809 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.593010e-03 2.798 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.715126e-03 2.766 0 0
Integrin signaling R-HSA-354192 1.800821e-03 2.745 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 1.800821e-03 2.745 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.878179e-03 2.726 0 0
Immune System R-HSA-168256 2.188925e-03 2.660 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.416692e-03 2.617 0 0
Regulation of TP53 Activity R-HSA-5633007 2.488552e-03 2.604 0 0
Regulation of CDH11 function R-HSA-9762292 2.685287e-03 2.571 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.896160e-03 2.538 0 0
Myogenesis R-HSA-525793 3.043453e-03 2.517 0 0
TRP channels R-HSA-3295583 3.043453e-03 2.517 0 0
HCMV Early Events R-HSA-9609690 3.336446e-03 2.477 0 0
Recycling pathway of L1 R-HSA-437239 3.172983e-03 2.499 0 0
Signaling by ERBB2 R-HSA-1227986 3.348312e-03 2.475 0 0
Interaction between L1 and Ankyrins R-HSA-445095 3.531441e-03 2.452 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 3.531441e-03 2.452 0 0
Ephrin signaling R-HSA-3928664 3.602507e-03 2.443 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 3.716905e-03 2.430 0 0
Protein ubiquitination R-HSA-8852135 3.940021e-03 2.405 0 0
Adaptive Immune System R-HSA-1280218 4.136808e-03 2.383 0 0
Signaling by ALK R-HSA-201556 4.426932e-03 2.354 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 4.678685e-03 2.330 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.678685e-03 2.330 0 0
Cytokine Signaling in Immune system R-HSA-1280215 4.892730e-03 2.310 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 5.345354e-03 2.272 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 5.374134e-03 2.270 0 0
PKMTs methylate histone lysines R-HSA-3214841 5.543954e-03 2.256 0 0
Signaling by LTK R-HSA-9842663 5.567623e-03 2.254 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 5.954460e-03 2.225 0 0
Signaling by Nuclear Receptors R-HSA-9006931 6.094222e-03 2.215 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 6.745253e-03 2.171 0 0
Signaling by ALK in cancer R-HSA-9700206 6.745253e-03 2.171 0 0
Transport of glycerol from adipocytes to the liver by Aquaporins R-HSA-432030 7.768508e-03 2.110 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 7.762062e-03 2.110 0 0
Signaling by NTRKs R-HSA-166520 7.033268e-03 2.153 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 8.394055e-03 2.076 0 0
HCMV Infection R-HSA-9609646 8.581724e-03 2.066 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 9.249451e-03 2.034 0 0
Death Receptor Signaling R-HSA-73887 9.503062e-03 2.022 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 9.680140e-03 2.014 0 0
RAF activation R-HSA-5673000 9.757108e-03 2.011 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.849985e-03 2.007 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 9.849985e-03 2.007 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 9.953535e-03 2.002 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.000895e-02 2.000 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.016695e-02 1.993 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.016695e-02 1.993 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.016695e-02 1.993 0 0
Signaling by RAS mutants R-HSA-6802949 1.016695e-02 1.993 0 0
Neurodegenerative Diseases R-HSA-8863678 1.065407e-02 1.972 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.065407e-02 1.972 0 0
Kinesins R-HSA-983189 1.072251e-02 1.970 0 0
Regulation of TP53 Expression R-HSA-6804754 1.342273e-02 1.872 0 0
Diseases of cellular response to stress R-HSA-9675132 1.342273e-02 1.872 0 0
Diseases of Cellular Senescence R-HSA-9630747 1.342273e-02 1.872 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.342273e-02 1.872 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.270165e-02 1.896 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.270165e-02 1.896 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.339657e-02 1.873 0 0
Voltage gated Potassium channels R-HSA-1296072 1.339657e-02 1.873 0 0
Co-stimulation by CD28 R-HSA-389356 1.219801e-02 1.914 0 0
HDMs demethylate histones R-HSA-3214842 1.212390e-02 1.916 0 0
Long-term potentiation R-HSA-9620244 1.212390e-02 1.916 0 0
Degradation of CDH1 R-HSA-9766229 1.331637e-02 1.876 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.356684e-02 1.868 0 0
Signaling by PTK6 R-HSA-8848021 1.356684e-02 1.868 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.396886e-02 1.855 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.546357e-02 1.811 0 0
Pyroptosis R-HSA-5620971 1.734272e-02 1.761 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.840485e-02 1.735 0 0
MHC class II antigen presentation R-HSA-2132295 1.845969e-02 1.734 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.880194e-02 1.726 0 0
Regulated Necrosis R-HSA-5218859 1.947436e-02 1.711 0 0
Signal attenuation R-HSA-74749 1.968348e-02 1.706 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.968348e-02 1.706 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.968348e-02 1.706 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 2.030730e-02 1.692 0 0
Axonal growth stimulation R-HSA-209563 2.038602e-02 1.691 0 0
MAP2K and MAPK activation R-HSA-5674135 2.140619e-02 1.669 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.156140e-02 1.666 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 2.228493e-02 1.652 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 2.382317e-02 1.623 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.635225e-02 1.579 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.350799e-02 1.629 0 0
Signaling by EGFR R-HSA-177929 2.327692e-02 1.633 0 0
G0 and Early G1 R-HSA-1538133 2.634925e-02 1.579 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 2.537014e-02 1.596 0 0
Signaling by FGFR4 R-HSA-5654743 2.535903e-02 1.596 0 0
Signaling by FGFR1 R-HSA-5654736 2.327692e-02 1.633 0 0
TNF signaling R-HSA-75893 2.327692e-02 1.633 0 0
Interleukin-2 signaling R-HSA-9020558 2.382317e-02 1.623 0 0
Regulation of CDH1 Function R-HSA-9764561 2.502984e-02 1.602 0 0
Gene expression (Transcription) R-HSA-74160 2.681707e-02 1.572 0 0
Nuclear Envelope Breakdown R-HSA-2980766 2.502984e-02 1.602 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.327692e-02 1.633 0 0
Post NMDA receptor activation events R-HSA-438064 2.636821e-02 1.579 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 2.696598e-02 1.569 0 0
Netrin-1 signaling R-HSA-373752 2.750622e-02 1.561 0 0
Muscle contraction R-HSA-397014 2.764174e-02 1.558 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 2.778958e-02 1.556 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 2.839657e-02 1.547 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 2.839657e-02 1.547 0 0
NADE modulates death signalling R-HSA-205025 2.853727e-02 1.545 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.853727e-02 1.545 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 2.853727e-02 1.545 0 0
Generic Transcription Pathway R-HSA-212436 2.894102e-02 1.538 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 2.899048e-02 1.538 0 0
Signaling by FGFR3 R-HSA-5654741 2.977023e-02 1.526 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 3.079479e-02 1.512 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.082543e-02 1.511 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.126510e-02 1.505 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.126510e-02 1.505 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.126510e-02 1.505 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.179324e-02 1.498 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 3.207836e-02 1.494 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 3.264716e-02 1.486 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 3.333418e-02 1.477 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 3.333418e-02 1.477 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 3.340119e-02 1.476 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 3.422436e-02 1.466 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 4.248071e-02 1.372 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 4.248071e-02 1.372 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 4.248071e-02 1.372 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 4.248071e-02 1.372 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 4.248071e-02 1.372 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 3.776328e-02 1.423 0 0
IRS activation R-HSA-74713 3.776328e-02 1.423 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 3.883219e-02 1.411 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 3.883219e-02 1.411 0 0
Formation of axial mesoderm R-HSA-9796292 3.883219e-02 1.411 0 0
mRNA Splicing R-HSA-72172 3.868376e-02 1.412 0 0
Signaling by FGFR2 R-HSA-5654738 4.067764e-02 1.391 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 3.745997e-02 1.426 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 4.003236e-02 1.398 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 4.003236e-02 1.398 0 0
PTEN Regulation R-HSA-6807070 4.288949e-02 1.368 0 0
IGF1R signaling cascade R-HSA-2428924 3.986452e-02 1.399 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 4.236762e-02 1.373 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 3.809216e-02 1.419 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 3.809216e-02 1.419 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 4.067764e-02 1.391 0 0
RNA Polymerase II Transcription R-HSA-73857 3.507399e-02 1.455 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 4.322901e-02 1.364 0 0
MyD88-independent TLR4 cascade R-HSA-166166 4.322901e-02 1.364 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 4.067764e-02 1.391 0 0
NrCAM interactions R-HSA-447038 3.776328e-02 1.423 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 3.475979e-02 1.459 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 4.465959e-02 1.350 0 0
Regulation of KIT signaling R-HSA-1433559 4.468270e-02 1.350 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 4.570983e-02 1.340 0 0
Tight junction interactions R-HSA-420029 4.761822e-02 1.322 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.795829e-02 1.319 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.795829e-02 1.319 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 4.829704e-02 1.316 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.902505e-02 1.310 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.903750e-02 1.309 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 5.047826e-02 1.297 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 5.094402e-02 1.293 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 5.099080e-02 1.293 0 0
Signaling by FGFR R-HSA-190236 5.135674e-02 1.289 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 5.135674e-02 1.289 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 5.135674e-02 1.289 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 5.135674e-02 1.289 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 5.210445e-02 1.283 0 0
Stabilization of p53 R-HSA-69541 5.210445e-02 1.283 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 5.210445e-02 1.283 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 5.229436e-02 1.282 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 5.232049e-02 1.281 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.608209e-02 1.251 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 5.608209e-02 1.251 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 5.608209e-02 1.251 0 0
Mitotic Anaphase R-HSA-68882 5.638140e-02 1.249 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.639463e-02 1.249 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 5.726636e-02 1.242 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 5.726636e-02 1.242 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.760590e-02 1.240 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.760590e-02 1.240 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 5.760590e-02 1.240 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 5.807285e-02 1.236 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.902358e-02 1.229 0 0
G2/M DNA replication checkpoint R-HSA-69478 5.902358e-02 1.229 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.902358e-02 1.229 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.950748e-02 1.225 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.950748e-02 1.225 0 0
Cardiac conduction R-HSA-5576891 5.954677e-02 1.225 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 7.086704e-02 1.150 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 7.086704e-02 1.150 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 7.086704e-02 1.150 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 7.208372e-02 1.142 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 6.787969e-02 1.168 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 6.787969e-02 1.168 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 7.354107e-02 1.133 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.354107e-02 1.133 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 7.354107e-02 1.133 0 0
Trafficking of AMPA receptors R-HSA-399719 7.943396e-02 1.100 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 7.943396e-02 1.100 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 7.943396e-02 1.100 0 0
Signaling by RAF1 mutants R-HSA-9656223 6.454735e-02 1.190 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 7.208372e-02 1.142 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 7.208372e-02 1.142 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 7.086704e-02 1.150 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 7.086704e-02 1.150 0 0
Passive transport by Aquaporins R-HSA-432047 6.465673e-02 1.189 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 7.208372e-02 1.142 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 6.604448e-02 1.180 0 0
G1 Phase R-HSA-69236 7.850977e-02 1.105 0 0
Cyclin D associated events in G1 R-HSA-69231 7.850977e-02 1.105 0 0
NRAGE signals death through JNK R-HSA-193648 6.283891e-02 1.202 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 7.406702e-02 1.130 0 0
EPHB-mediated forward signaling R-HSA-3928662 7.850977e-02 1.105 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 7.086704e-02 1.150 0 0
ISG15 antiviral mechanism R-HSA-1169408 7.299796e-02 1.137 0 0
Toll-like Receptor Cascades R-HSA-168898 7.847978e-02 1.105 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.140483e-02 1.212 0 0
Interleukin-1 family signaling R-HSA-446652 7.131991e-02 1.147 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 6.283891e-02 1.202 0 0
Interleukin-37 signaling R-HSA-9008059 7.354107e-02 1.133 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 7.944361e-02 1.100 0 0
GAB1 signalosome R-HSA-180292 7.987311e-02 1.098 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 7.987311e-02 1.098 0 0
Apoptotic factor-mediated response R-HSA-111471 7.987311e-02 1.098 0 0
Synaptic adhesion-like molecules R-HSA-8849932 7.987311e-02 1.098 0 0
Polo-like kinase mediated events R-HSA-156711 7.987311e-02 1.098 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 8.182528e-02 1.087 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 8.182528e-02 1.087 0 0
Stimuli-sensing channels R-HSA-2672351 8.182528e-02 1.087 0 0
Host Interactions of HIV factors R-HSA-162909 8.237152e-02 1.084 0 0
Diseases of Telomere Maintenance R-HSA-9673013 8.315927e-02 1.080 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 8.315927e-02 1.080 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 8.315927e-02 1.080 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 8.315927e-02 1.080 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 8.315927e-02 1.080 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 8.315927e-02 1.080 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 8.315927e-02 1.080 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 8.315927e-02 1.080 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 8.315927e-02 1.080 0 0
Inhibition of PKR R-HSA-169131 8.315927e-02 1.080 0 0
Type I hemidesmosome assembly R-HSA-446107 8.340278e-02 1.079 0 0
FGFR1b ligand binding and activation R-HSA-190370 8.340278e-02 1.079 0 0
Activation of RAS in B cells R-HSA-1169092 8.340278e-02 1.079 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 8.340278e-02 1.079 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 8.340278e-02 1.079 0 0
SLC-mediated bile acid transport R-HSA-9958517 8.340278e-02 1.079 0 0
G alpha (12/13) signalling events R-HSA-416482 8.420881e-02 1.075 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 8.504054e-02 1.070 0 0
Diseases of mitotic cell cycle R-HSA-9675126 8.555403e-02 1.068 0 0
Sensory processing of sound R-HSA-9659379 8.815300e-02 1.055 0 0
Regulation of TNFR1 signaling R-HSA-5357905 8.864610e-02 1.052 0 0
Signaling by TGFBR3 R-HSA-9839373 8.864610e-02 1.052 0 0
Nef mediated downregulation of CD28 cell surface expression R-HSA-164939 1.221121e-01 0.913 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 1.221121e-01 0.913 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 1.221121e-01 0.913 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 1.221121e-01 0.913 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 1.221121e-01 0.913 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 1.221121e-01 0.913 0 0
Defective CD320 causes MMATC R-HSA-3359485 1.221121e-01 0.913 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 1.221121e-01 0.913 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 1.221121e-01 0.913 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 1.221121e-01 0.913 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 1.221121e-01 0.913 0 0
WNT mediated activation of DVL R-HSA-201688 9.655082e-02 1.015 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 9.655082e-02 1.015 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.102367e-01 0.958 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 1.102367e-01 0.958 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.102367e-01 0.958 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.243911e-01 0.905 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 9.648017e-02 1.016 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 9.648017e-02 1.016 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 1.052668e-01 0.978 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 1.143541e-01 0.942 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.143541e-01 0.942 0 0
Notch-HLH transcription pathway R-HSA-350054 1.237255e-01 0.908 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.237255e-01 0.908 0 0
Interleukin receptor SHC signaling R-HSA-912526 1.333644e-01 0.875 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 9.189645e-02 1.037 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 9.189645e-02 1.037 0 0
Striated Muscle Contraction R-HSA-390522 9.845601e-02 1.007 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 9.845601e-02 1.007 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 1.122037e-01 0.950 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 1.122037e-01 0.950 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.122037e-01 0.950 0 0
RET signaling R-HSA-8853659 1.193795e-01 0.923 0 0
mRNA 3'-end processing R-HSA-72187 1.228417e-01 0.911 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.052668e-01 0.978 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.052668e-01 0.978 0 0
p75NTR regulates axonogenesis R-HSA-193697 9.655082e-02 1.015 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 1.267480e-01 0.897 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 9.655082e-02 1.015 0 0
Signalling to RAS R-HSA-167044 1.052668e-01 0.978 0 0
FOXO-mediated transcription R-HSA-9614085 1.102170e-01 0.958 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 9.395719e-02 1.027 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.102170e-01 0.958 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 9.655082e-02 1.015 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.337198e-01 0.874 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 9.655082e-02 1.015 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.827941e-02 1.008 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.243911e-01 0.905 0 0
Co-inhibition by CTLA4 R-HSA-389513 9.648017e-02 1.016 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.395719e-02 1.027 0 0
Signalling to ERKs R-HSA-187687 1.122037e-01 0.950 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.221121e-01 0.913 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.221121e-01 0.913 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 1.102367e-01 0.958 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.243911e-01 0.905 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.333644e-01 0.875 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 9.845601e-02 1.007 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.060762e-01 0.974 0 0
Formation of definitive endoderm R-HSA-9823730 9.648017e-02 1.016 0 0
Membrane Trafficking R-HSA-199991 1.126302e-01 0.948 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.217578e-01 0.915 0 0
G2/M Transition R-HSA-69275 1.155790e-01 0.937 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 9.845601e-02 1.007 0 0
GPER1 signaling R-HSA-9634597 9.942720e-02 1.002 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 1.143541e-01 0.942 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.317796e-01 0.880 0 0
Interleukin-1 signaling R-HSA-9020702 1.185958e-01 0.926 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.221121e-01 0.913 0 0
GP1b-IX-V activation signalling R-HSA-430116 9.655082e-02 1.015 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 9.655082e-02 1.015 0 0
Potassium Channels R-HSA-1296071 9.827941e-02 1.008 0 0
Receptor Mediated Mitophagy R-HSA-8934903 1.102367e-01 0.958 0 0
PECAM1 interactions R-HSA-210990 1.243911e-01 0.905 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.143541e-01 0.942 0 0
Nuclear import of Rev protein R-HSA-180746 1.052271e-01 0.978 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 9.864645e-02 1.006 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 1.096272e-01 0.960 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.317796e-01 0.880 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.143541e-01 0.942 0 0
Influenza Infection R-HSA-168255 9.543390e-02 1.020 0 0
Growth hormone receptor signaling R-HSA-982772 1.333644e-01 0.875 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.374267e-01 0.862 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.382948e-01 0.859 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.389497e-01 0.857 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.389497e-01 0.857 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.389497e-01 0.857 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 1.389497e-01 0.857 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.432539e-01 0.844 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 1.432539e-01 0.844 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.484836e-01 0.828 0 0
Ion homeostasis R-HSA-5578775 1.485560e-01 0.828 0 0
Interleukin-2 family signaling R-HSA-451927 1.499401e-01 0.824 0 0
TGFBR3 expression R-HSA-9839394 1.533773e-01 0.814 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 1.533773e-01 0.814 0 0
Formation of the nephric duct R-HSA-9830364 1.533773e-01 0.814 0 0
Interleukin-7 signaling R-HSA-1266695 1.533773e-01 0.814 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.538527e-01 0.813 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 1.538527e-01 0.813 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.538527e-01 0.813 0 0
VLDLR internalisation and degradation R-HSA-8866427 1.538527e-01 0.813 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.538527e-01 0.813 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.538527e-01 0.813 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 1.544191e-01 0.811 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.580088e-01 0.801 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.594122e-01 0.797 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.594122e-01 0.797 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.594122e-01 0.797 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.594122e-01 0.797 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.594122e-01 0.797 0 0
Signaling by EGFR in Cancer R-HSA-1643713 1.637179e-01 0.786 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 1.637179e-01 0.786 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 1.637179e-01 0.786 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 1.637179e-01 0.786 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.662341e-01 0.779 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.662341e-01 0.779 0 0
Intra-Golgi traffic R-HSA-6811438 1.662341e-01 0.779 0 0
FGFR1c ligand binding and activation R-HSA-190373 1.690448e-01 0.772 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.690448e-01 0.772 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.690448e-01 0.772 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.690448e-01 0.772 0 0
snRNP Assembly R-HSA-191859 1.692066e-01 0.772 0 0
Metabolism of non-coding RNA R-HSA-194441 1.692066e-01 0.772 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.701829e-01 0.769 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.951296e-01 0.710 0 0
MET activates PTPN11 R-HSA-8865999 1.951296e-01 0.710 0 0
Classical Kir channels R-HSA-1296053 1.951296e-01 0.710 0 0
Invadopodia formation R-HSA-8941237 1.951296e-01 0.710 0 0
ATP sensitive Potassium channels R-HSA-1296025 2.293315e-01 0.640 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.293315e-01 0.640 0 0
Nucleotide catabolism defects R-HSA-9735786 2.293315e-01 0.640 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.293315e-01 0.640 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 2.293315e-01 0.640 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.293315e-01 0.640 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.293315e-01 0.640 0 0
Activation of AMPA receptors R-HSA-399710 2.620819e-01 0.582 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.620819e-01 0.582 0 0
G2 Phase R-HSA-68911 2.620819e-01 0.582 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 2.620819e-01 0.582 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 2.934426e-01 0.532 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.934426e-01 0.532 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 2.934426e-01 0.532 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.934426e-01 0.532 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 2.934426e-01 0.532 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.844745e-01 0.734 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.844745e-01 0.734 0 0
Autointegration results in viral DNA circles R-HSA-177539 3.234722e-01 0.490 0 0
SHC1 events in EGFR signaling R-HSA-180336 2.000944e-01 0.699 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 2.000944e-01 0.699 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.158606e-01 0.666 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 2.317324e-01 0.635 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 1.742588e-01 0.759 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.476726e-01 0.606 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.636467e-01 0.579 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 2.069208e-01 0.684 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 2.796231e-01 0.553 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 2.955729e-01 0.529 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 3.114695e-01 0.507 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 3.114695e-01 0.507 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 3.272886e-01 0.485 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 3.430083e-01 0.465 0 0
FGFR2 alternative splicing R-HSA-6803529 3.430083e-01 0.465 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 2.448845e-01 0.611 0 0
Post-translational protein phosphorylation R-HSA-8957275 1.991067e-01 0.701 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.271218e-01 0.644 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.271218e-01 0.644 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.934584e-01 0.532 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 3.030991e-01 0.518 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.697979e-01 0.569 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.771006e-01 0.557 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 3.067321e-01 0.513 0 0
Formation of a pool of free 40S subunits R-HSA-72689 3.142287e-01 0.503 0 0
PKR-mediated signaling R-HSA-9833482 3.359313e-01 0.474 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 3.114695e-01 0.507 0 0
Chaperonin-mediated protein folding R-HSA-390466 2.411079e-01 0.618 0 0
Separation of Sister Chromatids R-HSA-2467813 1.731820e-01 0.761 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 2.317324e-01 0.635 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 2.636467e-01 0.579 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.844745e-01 0.734 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.084042e-01 0.511 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 3.142287e-01 0.503 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 3.217542e-01 0.492 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 2.000944e-01 0.699 0 0
Protein folding R-HSA-391251 2.844487e-01 0.546 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.934426e-01 0.532 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 1.742588e-01 0.759 0 0
Peptide chain elongation R-HSA-156902 2.481956e-01 0.605 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.638822e-01 0.579 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.430083e-01 0.465 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.989343e-01 0.524 0 0
Killing mechanisms R-HSA-9664420 2.158606e-01 0.666 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 2.158606e-01 0.666 0 0
Insulin receptor signalling cascade R-HSA-74751 2.058834e-01 0.686 0 0
Regulation of gap junction activity R-HSA-191650 2.293315e-01 0.640 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 2.317324e-01 0.635 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 3.430083e-01 0.465 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.743082e-01 0.562 0 0
Mitotic Spindle Checkpoint R-HSA-69618 2.111834e-01 0.675 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 2.158606e-01 0.666 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 2.620819e-01 0.582 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 2.638822e-01 0.579 0 0
MET promotes cell motility R-HSA-8875878 3.106847e-01 0.508 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.943196e-01 0.711 0 0
Adipogenesis R-HSA-9843745 3.095116e-01 0.509 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.069208e-01 0.684 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 2.317324e-01 0.635 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 2.872088e-01 0.542 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 3.127740e-01 0.505 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.363464e-01 0.626 0 0
Mitophagy R-HSA-5205647 2.638822e-01 0.579 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 2.293315e-01 0.640 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 2.293315e-01 0.640 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.620819e-01 0.582 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 2.000944e-01 0.699 0 0
p38MAPK events R-HSA-171007 2.000944e-01 0.699 0 0
Regulation of RAS by GAPs R-HSA-5658442 2.460200e-01 0.609 0 0
Eukaryotic Translation Termination R-HSA-72764 3.142287e-01 0.503 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 2.691526e-01 0.570 0 0
FGFR1 ligand binding and activation R-HSA-190242 2.636467e-01 0.579 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 3.139520e-01 0.503 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 3.342131e-01 0.476 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 2.389291e-01 0.622 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.317324e-01 0.635 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.636467e-01 0.579 0 0
PCP/CE pathway R-HSA-4086400 1.741759e-01 0.759 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.041646e-01 0.690 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.158606e-01 0.666 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 3.067321e-01 0.513 0 0
Dopamine receptors R-HSA-390651 2.293315e-01 0.640 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.620819e-01 0.582 0 0
Synthesis of PS R-HSA-1483101 2.934426e-01 0.532 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.934426e-01 0.532 0 0
Ceramide signalling R-HSA-193681 2.934426e-01 0.532 0 0
Intracellular metabolism of fatty acids regulates insulin secretion R-HSA-434313 3.234722e-01 0.490 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 1.849838e-01 0.733 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.005456e-01 0.698 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.983432e-01 0.703 0 0
S Phase R-HSA-69242 1.899656e-01 0.721 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 2.755205e-01 0.560 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 2.529112e-01 0.597 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.844487e-01 0.546 0 0
Signaling by NOTCH1 R-HSA-1980143 3.022541e-01 0.520 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.620819e-01 0.582 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.849838e-01 0.733 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 1.958764e-01 0.708 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 2.638822e-01 0.579 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 3.342131e-01 0.476 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 3.342131e-01 0.476 0 0
Protein-protein interactions at synapses R-HSA-6794362 2.202300e-01 0.657 0 0
Platelet activation, signaling and aggregation R-HSA-76002 2.139691e-01 0.670 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.293315e-01 0.640 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 1.844745e-01 0.734 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.158606e-01 0.666 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 2.408092e-01 0.618 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 2.751397e-01 0.560 0 0
Regulation of PTEN stability and activity R-HSA-8948751 2.743082e-01 0.562 0 0
Regulation of BACH1 activity R-HSA-9708530 2.158606e-01 0.666 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 1.849838e-01 0.733 0 0
Cardiogenesis R-HSA-9733709 2.408092e-01 0.618 0 0
Ca2+ pathway R-HSA-4086398 2.773578e-01 0.557 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 2.138378e-01 0.670 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 2.408092e-01 0.618 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 3.342131e-01 0.476 0 0
Diseases of Immune System R-HSA-5260271 3.342131e-01 0.476 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.746082e-01 0.758 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.951296e-01 0.710 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 1.951296e-01 0.710 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 2.293315e-01 0.640 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.620819e-01 0.582 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.934426e-01 0.532 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 3.234722e-01 0.490 0 0
Activation of SMO R-HSA-5635838 2.158606e-01 0.666 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.636467e-01 0.579 0 0
Specification of the neural plate border R-HSA-9834899 2.796231e-01 0.553 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 2.181012e-01 0.661 0 0
Regulation of necroptotic cell death R-HSA-5675482 2.408092e-01 0.618 0 0
Effects of PIP2 hydrolysis R-HSA-114508 2.523072e-01 0.598 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.638822e-01 0.579 0 0
Neuronal System R-HSA-112316 2.301251e-01 0.638 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 1.958764e-01 0.708 0 0
HIV Infection R-HSA-162906 2.802235e-01 0.552 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.934426e-01 0.532 0 0
Metabolism of RNA R-HSA-8953854 2.284463e-01 0.641 0 0
Histamine receptors R-HSA-390650 1.951296e-01 0.710 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.234722e-01 0.490 0 0
Rap1 signalling R-HSA-392517 2.796231e-01 0.553 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 2.408092e-01 0.618 0 0
tRNA processing in the nucleus R-HSA-6784531 1.909009e-01 0.719 0 0
RUNX2 regulates bone development R-HSA-8941326 2.872088e-01 0.542 0 0
G1/S Transition R-HSA-69206 2.661418e-01 0.575 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 3.106847e-01 0.508 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.000944e-01 0.699 0 0
Activation of BH3-only proteins R-HSA-114452 2.069208e-01 0.684 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.860173e-01 0.730 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 1.951296e-01 0.710 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.293315e-01 0.640 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.620819e-01 0.582 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.620819e-01 0.582 0 0
Co-inhibition by BTLA R-HSA-9927353 2.620819e-01 0.582 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.934426e-01 0.532 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.958764e-01 0.708 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.835609e-01 0.736 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.224481e-01 0.492 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 2.638822e-01 0.579 0 0
Platelet sensitization by LDL R-HSA-432142 2.636467e-01 0.579 0 0
Ion channel transport R-HSA-983712 1.985468e-01 0.702 0 0
Hedgehog 'on' state R-HSA-5632684 2.610022e-01 0.583 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.620819e-01 0.582 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 2.934426e-01 0.532 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 2.934426e-01 0.532 0 0
Signal regulatory protein family interactions R-HSA-391160 1.844745e-01 0.734 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 3.234722e-01 0.490 0 0
Synthesis of PG R-HSA-1483148 2.317324e-01 0.635 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 2.094370e-01 0.679 0 0
Mitochondrial calcium ion transport R-HSA-8949215 3.272886e-01 0.485 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 3.430083e-01 0.465 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 3.224481e-01 0.492 0 0
Signaling by NOTCH4 R-HSA-9013694 2.856129e-01 0.544 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.275407e-01 0.643 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 2.000944e-01 0.699 0 0
Signal transduction by L1 R-HSA-445144 2.955729e-01 0.529 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 2.934426e-01 0.532 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 2.158606e-01 0.666 0 0
Regulation of beta-cell development R-HSA-186712 3.321991e-01 0.479 0 0
LDL clearance R-HSA-8964038 3.430083e-01 0.465 0 0
Viral Infection Pathways R-HSA-9824446 2.898056e-01 0.538 0 0
Assembly Of The HIV Virion R-HSA-175474 3.272886e-01 0.485 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.114695e-01 0.507 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 3.156751e-01 0.501 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 3.106847e-01 0.508 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.459687e-01 0.461 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 3.459687e-01 0.461 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 3.459687e-01 0.461 0 0
FLT3 Signaling R-HSA-9607240 3.459687e-01 0.461 0 0
Developmental Cell Lineages R-HSA-9734767 3.481300e-01 0.458 0 0
HIV Life Cycle R-HSA-162587 3.510057e-01 0.455 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 3.516802e-01 0.454 0 0
Aquaporin-mediated transport R-HSA-445717 3.516802e-01 0.454 0 0
Viral Messenger RNA Synthesis R-HSA-168325 3.516802e-01 0.454 0 0
MAP kinase activation R-HSA-450294 3.516802e-01 0.454 0 0
Hedgehog 'off' state R-HSA-5610787 3.520809e-01 0.453 0 0
Glycolysis R-HSA-70171 3.520809e-01 0.453 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.522273e-01 0.453 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 3.522273e-01 0.453 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.522273e-01 0.453 0 0
SOS-mediated signalling R-HSA-112412 3.522273e-01 0.453 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 3.522273e-01 0.453 0 0
FGFR3b ligand binding and activation R-HSA-190371 3.522273e-01 0.453 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 3.522273e-01 0.453 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.522273e-01 0.453 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 3.522273e-01 0.453 0 0
Netrin mediated repulsion signals R-HSA-418886 3.522273e-01 0.453 0 0
Cellular response to starvation R-HSA-9711097 3.570387e-01 0.447 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 3.571808e-01 0.447 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 3.577047e-01 0.446 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.586084e-01 0.445 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.586084e-01 0.445 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 3.586084e-01 0.445 0 0
Syndecan interactions R-HSA-3000170 3.586084e-01 0.445 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.597030e-01 0.444 0 0
Selenocysteine synthesis R-HSA-2408557 3.597030e-01 0.444 0 0
Ribosome-associated quality control R-HSA-9948299 3.606706e-01 0.443 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 3.614259e-01 0.442 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 3.663672e-01 0.436 0 0
PI Metabolism R-HSA-1483255 3.673350e-01 0.435 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 3.694109e-01 0.432 0 0
Ca-dependent events R-HSA-111996 3.694109e-01 0.432 0 0
Cellular response to heat stress R-HSA-3371556 3.711409e-01 0.430 0 0
Leishmania phagocytosis R-HSA-9664417 3.736169e-01 0.428 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 3.736169e-01 0.428 0 0
Parasite infection R-HSA-9664407 3.736169e-01 0.428 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 3.740707e-01 0.427 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 3.740707e-01 0.427 0 0
Deadenylation of mRNA R-HSA-429947 3.740707e-01 0.427 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 3.740707e-01 0.427 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 3.740707e-01 0.427 0 0
Viral mRNA Translation R-HSA-192823 3.749740e-01 0.426 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 3.784018e-01 0.422 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.797619e-01 0.420 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.797619e-01 0.420 0 0
phospho-PLA2 pathway R-HSA-111995 3.797619e-01 0.420 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 3.797619e-01 0.420 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 3.797619e-01 0.420 0 0
MET receptor recycling R-HSA-8875656 3.797619e-01 0.420 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 3.797619e-01 0.420 0 0
Formation of annular gap junctions R-HSA-196025 3.797619e-01 0.420 0 0
Regulation by c-FLIP R-HSA-3371378 3.797619e-01 0.420 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 3.797619e-01 0.420 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.797619e-01 0.420 0 0
Dimerization of procaspase-8 R-HSA-69416 3.797619e-01 0.420 0 0
Adrenoceptors R-HSA-390696 3.797619e-01 0.420 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 3.797619e-01 0.420 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 3.797619e-01 0.420 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 3.808970e-01 0.419 0 0
Signaling by SCF-KIT R-HSA-1433557 3.810779e-01 0.419 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 3.826170e-01 0.417 0 0
Hemostasis R-HSA-109582 3.843044e-01 0.415 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 3.893787e-01 0.410 0 0
Acyl chain remodelling of PS R-HSA-1482801 3.893787e-01 0.410 0 0
SARS-CoV-2-host interactions R-HSA-9705683 3.925065e-01 0.406 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 3.926967e-01 0.406 0 0
Amine ligand-binding receptors R-HSA-375280 3.926967e-01 0.406 0 0
Late Phase of HIV Life Cycle R-HSA-162599 3.930927e-01 0.406 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 3.930927e-01 0.406 0 0
Phospholipid metabolism R-HSA-1483257 3.946607e-01 0.404 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.995924e-01 0.398 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 4.042588e-01 0.393 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 4.042588e-01 0.393 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 4.042588e-01 0.393 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 4.045178e-01 0.393 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 4.045178e-01 0.393 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.045178e-01 0.393 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 4.061277e-01 0.391 0 0
Regulated proteolysis of p75NTR R-HSA-193692 4.061277e-01 0.391 0 0
Gap junction degradation R-HSA-190873 4.061277e-01 0.391 0 0
CASP8 activity is inhibited R-HSA-5218900 4.061277e-01 0.391 0 0
ALK mutants bind TKIs R-HSA-9700645 4.061277e-01 0.391 0 0
Calcineurin activates NFAT R-HSA-2025928 4.061277e-01 0.391 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 4.061277e-01 0.391 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 4.061277e-01 0.391 0 0
ARMS-mediated activation R-HSA-170984 4.061277e-01 0.391 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 4.061277e-01 0.391 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 4.061277e-01 0.391 0 0
Interleukin-1 processing R-HSA-448706 4.061277e-01 0.391 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 4.061277e-01 0.391 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 4.061277e-01 0.391 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 4.061277e-01 0.391 0 0
Selective autophagy R-HSA-9663891 4.123531e-01 0.385 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.131704e-01 0.384 0 0
rRNA processing R-HSA-72312 4.133712e-01 0.384 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 4.194746e-01 0.377 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 4.194746e-01 0.377 0 0
Signaling by FGFR3 in disease R-HSA-5655332 4.194746e-01 0.377 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 4.194746e-01 0.377 0 0
Transmission across Chemical Synapses R-HSA-112315 4.204110e-01 0.376 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 4.207901e-01 0.376 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 4.207901e-01 0.376 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.271806e-01 0.369 0 0
Synthesis of PC R-HSA-1483191 4.271806e-01 0.369 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 4.313742e-01 0.365 0 0
Folding of actin by CCT/TriC R-HSA-390450 4.313742e-01 0.365 0 0
PI3K/AKT activation R-HSA-198203 4.313742e-01 0.365 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 4.313742e-01 0.365 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 4.313742e-01 0.365 0 0
2-LTR circle formation R-HSA-164843 4.313742e-01 0.365 0 0
Pexophagy R-HSA-9664873 4.313742e-01 0.365 0 0
Signaling by Leptin R-HSA-2586552 4.313742e-01 0.365 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 4.313742e-01 0.365 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.336811e-01 0.363 0 0
Telomere Extension By Telomerase R-HSA-171319 4.342372e-01 0.362 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 4.342372e-01 0.362 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 4.342372e-01 0.362 0 0
NGF-stimulated transcription R-HSA-9031628 4.385256e-01 0.358 0 0
Interleukin-17 signaling R-HSA-448424 4.387473e-01 0.358 0 0
Mitotic Prometaphase R-HSA-68877 4.394285e-01 0.357 0 0
Innate Immune System R-HSA-168249 4.438005e-01 0.353 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 4.487952e-01 0.348 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 4.487952e-01 0.348 0 0
Signaling by Erythropoietin R-HSA-9006335 4.487952e-01 0.348 0 0
Late endosomal microautophagy R-HSA-9615710 4.487952e-01 0.348 0 0
Gap junction trafficking and regulation R-HSA-157858 4.497840e-01 0.347 0 0
DNA Damage Bypass R-HSA-73893 4.497840e-01 0.347 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 4.511144e-01 0.346 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 4.511144e-01 0.346 0 0
Signaling by Insulin receptor R-HSA-74752 4.543652e-01 0.343 0 0
Vesicle-mediated transport R-HSA-5653656 4.548121e-01 0.342 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 4.555489e-01 0.341 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 4.555489e-01 0.341 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 4.555489e-01 0.341 0 0
FGFR2b ligand binding and activation R-HSA-190377 4.555489e-01 0.341 0 0
vRNA Synthesis R-HSA-192814 4.555489e-01 0.341 0 0
Synthesis of PI R-HSA-1483226 4.555489e-01 0.341 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 4.555489e-01 0.341 0 0
Transport of RCbl within the body R-HSA-9758890 4.555489e-01 0.341 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.555489e-01 0.341 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 4.555489e-01 0.341 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 4.555489e-01 0.341 0 0
Prostanoid ligand receptors R-HSA-391908 4.555489e-01 0.341 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 4.577080e-01 0.339 0 0
Azathioprine ADME R-HSA-9748787 4.609495e-01 0.336 0 0
PI3K Cascade R-HSA-109704 4.609495e-01 0.336 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 4.626766e-01 0.335 0 0
DAP12 signaling R-HSA-2424491 4.631393e-01 0.334 0 0
Switching of origins to a post-replicative state R-HSA-69052 4.671074e-01 0.331 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 4.671074e-01 0.331 0 0
HSF1-dependent transactivation R-HSA-3371571 4.720161e-01 0.326 0 0
Signaling by ERBB4 R-HSA-1236394 4.764473e-01 0.322 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 4.772614e-01 0.321 0 0
EGFR downregulation R-HSA-182971 4.772614e-01 0.321 0 0
Budding and maturation of HIV virion R-HSA-162588 4.772614e-01 0.321 0 0
Cargo concentration in the ER R-HSA-5694530 4.772614e-01 0.321 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.772614e-01 0.321 0 0
Downstream signal transduction R-HSA-186763 4.772614e-01 0.321 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 4.786973e-01 0.320 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.786973e-01 0.320 0 0
Signaling by GSK3beta mutants R-HSA-5339716 4.786973e-01 0.320 0 0
Integration of provirus R-HSA-162592 4.786973e-01 0.320 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 4.786973e-01 0.320 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 4.786973e-01 0.320 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.786973e-01 0.320 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.786973e-01 0.320 0 0
NF-kB is activated and signals survival R-HSA-209560 4.786973e-01 0.320 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 4.786973e-01 0.320 0 0
Plasmalogen biosynthesis R-HSA-75896 4.786973e-01 0.320 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.786973e-01 0.320 0 0
Activation of RAC1 R-HSA-428540 4.786973e-01 0.320 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 4.786973e-01 0.320 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.786973e-01 0.320 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.829784e-01 0.316 0 0
Orc1 removal from chromatin R-HSA-68949 4.829784e-01 0.316 0 0
Autophagy R-HSA-9612973 4.835495e-01 0.316 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 4.911545e-01 0.309 0 0
Inwardly rectifying K+ channels R-HSA-1296065 4.911545e-01 0.309 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.938310e-01 0.306 0 0
Smooth Muscle Contraction R-HSA-445355 4.938310e-01 0.306 0 0
Eukaryotic Translation Initiation R-HSA-72613 4.958678e-01 0.305 0 0
Cap-dependent Translation Initiation R-HSA-72737 4.958678e-01 0.305 0 0
Signaling by ROBO receptors R-HSA-376176 4.964316e-01 0.304 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 5.008628e-01 0.300 0 0
p75NTR recruits signalling complexes R-HSA-209543 5.008628e-01 0.300 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 5.008628e-01 0.300 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 5.008628e-01 0.300 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 5.008628e-01 0.300 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 5.008628e-01 0.300 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 5.008628e-01 0.300 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 5.008628e-01 0.300 0 0
IRAK1 recruits IKK complex R-HSA-937039 5.008628e-01 0.300 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 5.008628e-01 0.300 0 0
Repression of WNT target genes R-HSA-4641265 5.008628e-01 0.300 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 5.008628e-01 0.300 0 0
GRB2 events in EGFR signaling R-HSA-179812 5.008628e-01 0.300 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 5.008628e-01 0.300 0 0
MET activates RAS signaling R-HSA-8851805 5.008628e-01 0.300 0 0
Interleukin-15 signaling R-HSA-8983432 5.008628e-01 0.300 0 0
Regulation of IFNG signaling R-HSA-877312 5.008628e-01 0.300 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 5.008628e-01 0.300 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 5.008628e-01 0.300 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 5.008628e-01 0.300 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 5.008628e-01 0.300 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 5.008628e-01 0.300 0 0
Glucose metabolism R-HSA-70326 5.032121e-01 0.298 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 5.045692e-01 0.297 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 5.045692e-01 0.297 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 5.048124e-01 0.297 0 0
G-protein beta:gamma signalling R-HSA-397795 5.048124e-01 0.297 0 0
Neutrophil degranulation R-HSA-6798695 5.081353e-01 0.294 0 0
Signaling by TGFB family members R-HSA-9006936 5.088568e-01 0.293 0 0
Signaling by Hedgehog R-HSA-5358351 5.096082e-01 0.293 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 5.131392e-01 0.290 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 5.151886e-01 0.288 0 0
Signaling by NOTCH3 R-HSA-9012852 5.151886e-01 0.288 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 5.182302e-01 0.285 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 5.182302e-01 0.285 0 0
Heme degradation R-HSA-189483 5.182302e-01 0.285 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 5.220871e-01 0.282 0 0
Adenylate cyclase activating pathway R-HSA-170660 5.220871e-01 0.282 0 0
FGFR2c ligand binding and activation R-HSA-190375 5.220871e-01 0.282 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 5.220871e-01 0.282 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 5.220871e-01 0.282 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 5.220871e-01 0.282 0 0
CD28 dependent Vav1 pathway R-HSA-389359 5.220871e-01 0.282 0 0
FGFR4 ligand binding and activation R-HSA-190322 5.220871e-01 0.282 0 0
Frs2-mediated activation R-HSA-170968 5.220871e-01 0.282 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 5.220871e-01 0.282 0 0
Diseases of nucleotide metabolism R-HSA-9735804 5.220871e-01 0.282 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 5.220871e-01 0.282 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 5.220871e-01 0.282 0 0
FGFR3 mutant receptor activation R-HSA-2033514 5.220871e-01 0.282 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.220871e-01 0.282 0 0
Signaling by MET R-HSA-6806834 5.310375e-01 0.275 0 0
Signaling by NOTCH2 R-HSA-1980145 5.314034e-01 0.275 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 5.314034e-01 0.275 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 5.314034e-01 0.275 0 0
Signal amplification R-HSA-392518 5.314034e-01 0.275 0 0
IRS-mediated signalling R-HSA-112399 5.360549e-01 0.271 0 0
Synthesis of PA R-HSA-1483166 5.360549e-01 0.271 0 0
Prolactin receptor signaling R-HSA-1170546 5.424102e-01 0.266 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 5.424102e-01 0.266 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 5.424102e-01 0.266 0 0
CRMPs in Sema3A signaling R-HSA-399956 5.424102e-01 0.266 0 0
NRIF signals cell death from the nucleus R-HSA-205043 5.424102e-01 0.266 0 0
FGFR3c ligand binding and activation R-HSA-190372 5.424102e-01 0.266 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.424102e-01 0.266 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 5.424102e-01 0.266 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 5.424102e-01 0.266 0 0
Hydrolysis of LPC R-HSA-1483115 5.424102e-01 0.266 0 0
Signaling by FGFR4 in disease R-HSA-5655291 5.424102e-01 0.266 0 0
Non-canonical inflammasome activation R-HSA-9686114 5.424102e-01 0.266 0 0
HDL assembly R-HSA-8963896 5.424102e-01 0.266 0 0
Acyl chain remodeling of CL R-HSA-1482798 5.424102e-01 0.266 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.424102e-01 0.266 0 0
Parasitic Infection Pathways R-HSA-9824443 5.452149e-01 0.263 0 0
Leishmania infection R-HSA-9658195 5.452149e-01 0.263 0 0
GPVI-mediated activation cascade R-HSA-114604 5.570034e-01 0.254 0 0
G1/S-Specific Transcription R-HSA-69205 5.570034e-01 0.254 0 0
Calmodulin induced events R-HSA-111933 5.570034e-01 0.254 0 0
CaM pathway R-HSA-111997 5.570034e-01 0.254 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 5.572600e-01 0.254 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 5.618702e-01 0.250 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.618702e-01 0.250 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.618702e-01 0.250 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.618702e-01 0.250 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 5.618702e-01 0.250 0 0
p75NTR signals via NF-kB R-HSA-193639 5.618702e-01 0.250 0 0
Erythropoietin activates RAS R-HSA-9027284 5.618702e-01 0.250 0 0
Telomere C-strand synthesis initiation R-HSA-174430 5.618702e-01 0.250 0 0
DCC mediated attractive signaling R-HSA-418885 5.618702e-01 0.250 0 0
FGFR3 ligand binding and activation R-HSA-190239 5.618702e-01 0.250 0 0
Translesion synthesis by REV1 R-HSA-110312 5.618702e-01 0.250 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 5.618702e-01 0.250 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.618702e-01 0.250 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.618702e-01 0.250 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 5.618702e-01 0.250 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 5.618702e-01 0.250 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 5.618702e-01 0.250 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.618702e-01 0.250 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.663714e-01 0.247 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.663714e-01 0.247 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.663714e-01 0.247 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.663714e-01 0.247 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.663714e-01 0.247 0 0
Degradation of DVL R-HSA-4641258 5.694254e-01 0.245 0 0
Ovarian tumor domain proteases R-HSA-5689896 5.694254e-01 0.245 0 0
Formation of paraxial mesoderm R-HSA-9793380 5.762034e-01 0.239 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.762034e-01 0.239 0 0
PLC beta mediated events R-HSA-112043 5.762034e-01 0.239 0 0
Nucleotide salvage R-HSA-8956321 5.762034e-01 0.239 0 0
Translesion synthesis by POLI R-HSA-5656121 5.805038e-01 0.236 0 0
Phosphorylation of the APC/C R-HSA-176412 5.805038e-01 0.236 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.805038e-01 0.236 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.805038e-01 0.236 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.805038e-01 0.236 0 0
Prolonged ERK activation events R-HSA-169893 5.805038e-01 0.236 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 5.805038e-01 0.236 0 0
Differentiation of T cells R-HSA-9945266 5.805038e-01 0.236 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.805038e-01 0.236 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.805038e-01 0.236 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 5.805038e-01 0.236 0 0
Negative regulation of FLT3 R-HSA-9706369 5.805038e-01 0.236 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.805038e-01 0.236 0 0
SARS-CoV-1-host interactions R-HSA-9692914 5.813784e-01 0.236 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 5.815931e-01 0.235 0 0
Purine salvage R-HSA-74217 5.815931e-01 0.235 0 0
Interferon Signaling R-HSA-913531 5.848256e-01 0.233 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 5.858945e-01 0.232 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.858945e-01 0.232 0 0
Heme signaling R-HSA-9707616 5.858945e-01 0.232 0 0
Disease R-HSA-1643685 5.895032e-01 0.230 0 0
XBP1(S) activates chaperone genes R-HSA-381038 5.909572e-01 0.228 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 5.935059e-01 0.227 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 5.935059e-01 0.227 0 0
Plasma lipoprotein clearance R-HSA-8964043 5.935059e-01 0.227 0 0
Potential therapeutics for SARS R-HSA-9679191 5.938742e-01 0.226 0 0
Cellular response to chemical stress R-HSA-9711123 5.958795e-01 0.225 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 5.983460e-01 0.223 0 0
Translesion synthesis by POLK R-HSA-5655862 5.983460e-01 0.223 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.983460e-01 0.223 0 0
Scavenging by Class B Receptors R-HSA-3000471 5.983460e-01 0.223 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.983460e-01 0.223 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.983460e-01 0.223 0 0
Galactose catabolism R-HSA-70370 5.983460e-01 0.223 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.983460e-01 0.223 0 0
Ion transport by P-type ATPases R-HSA-936837 6.048469e-01 0.218 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 6.051634e-01 0.218 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 6.061820e-01 0.217 0 0
Cellular response to hypoxia R-HSA-1234174 6.141050e-01 0.212 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 6.154303e-01 0.211 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 6.154303e-01 0.211 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 6.154303e-01 0.211 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 6.154303e-01 0.211 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 6.154303e-01 0.211 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 6.154303e-01 0.211 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 6.154303e-01 0.211 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 6.154303e-01 0.211 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 6.154303e-01 0.211 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 6.165656e-01 0.210 0 0
Circadian clock R-HSA-9909396 6.208462e-01 0.207 0 0
PPARA activates gene expression R-HSA-1989781 6.242691e-01 0.205 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 6.261839e-01 0.203 0 0
Signaling by FGFR1 in disease R-HSA-5655302 6.277134e-01 0.202 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.317890e-01 0.199 0 0
Activated point mutants of FGFR2 R-HSA-2033519 6.317890e-01 0.199 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.317890e-01 0.199 0 0
PKA activation in glucagon signalling R-HSA-164378 6.317890e-01 0.199 0 0
Mismatch Repair R-HSA-5358508 6.317890e-01 0.199 0 0
Transport of connexons to the plasma membrane R-HSA-190872 6.317890e-01 0.199 0 0
PKA activation R-HSA-163615 6.317890e-01 0.199 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 6.317890e-01 0.199 0 0
Tie2 Signaling R-HSA-210993 6.317890e-01 0.199 0 0
G-protein mediated events R-HSA-112040 6.321787e-01 0.199 0 0
Kidney development R-HSA-9830369 6.321787e-01 0.199 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 6.360680e-01 0.196 0 0
IRE1alpha activates chaperones R-HSA-381070 6.385568e-01 0.195 0 0
Activation of GABAB receptors R-HSA-991365 6.386076e-01 0.195 0 0
GABA B receptor activation R-HSA-977444 6.386076e-01 0.195 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 6.386076e-01 0.195 0 0
MTOR signalling R-HSA-165159 6.386076e-01 0.195 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.474527e-01 0.189 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.474527e-01 0.189 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 6.474527e-01 0.189 0 0
Germ layer formation at gastrulation R-HSA-9754189 6.474527e-01 0.189 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.474527e-01 0.189 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.474527e-01 0.189 0 0
Regulation of signaling by CBL R-HSA-912631 6.474527e-01 0.189 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.474527e-01 0.189 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 6.474527e-01 0.189 0 0
Translesion Synthesis by POLH R-HSA-110320 6.474527e-01 0.189 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 6.474527e-01 0.189 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 6.474527e-01 0.189 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 6.474527e-01 0.189 0 0
Other interleukin signaling R-HSA-449836 6.474527e-01 0.189 0 0
The NLRP3 inflammasome R-HSA-844456 6.474527e-01 0.189 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.474527e-01 0.189 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 6.521295e-01 0.186 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 6.581713e-01 0.182 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 6.583731e-01 0.182 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 6.587706e-01 0.181 0 0
Interferon alpha/beta signaling R-HSA-909733 6.587706e-01 0.181 0 0
DAP12 interactions R-HSA-2172127 6.596413e-01 0.181 0 0
RMTs methylate histone arginines R-HSA-3214858 6.596413e-01 0.181 0 0
Gap junction trafficking R-HSA-190828 6.596413e-01 0.181 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 6.624511e-01 0.179 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.624511e-01 0.179 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 6.624511e-01 0.179 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.624511e-01 0.179 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.624511e-01 0.179 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.624511e-01 0.179 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 6.624511e-01 0.179 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.624511e-01 0.179 0 0
Acyl chain remodelling of PI R-HSA-1482922 6.624511e-01 0.179 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.624511e-01 0.179 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 6.624511e-01 0.179 0 0
Glycogen synthesis R-HSA-3322077 6.624511e-01 0.179 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 6.697846e-01 0.174 0 0
Somitogenesis R-HSA-9824272 6.697846e-01 0.174 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 6.697846e-01 0.174 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 6.697846e-01 0.174 0 0
DAG and IP3 signaling R-HSA-1489509 6.697846e-01 0.174 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.747498e-01 0.171 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 6.768122e-01 0.170 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 6.768122e-01 0.170 0 0
FGFR2 ligand binding and activation R-HSA-190241 6.768122e-01 0.170 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.768122e-01 0.170 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.768122e-01 0.170 0 0
Early Phase of HIV Life Cycle R-HSA-162594 6.768122e-01 0.170 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.768122e-01 0.170 0 0
ERK/MAPK targets R-HSA-198753 6.768122e-01 0.170 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 6.768122e-01 0.170 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.768122e-01 0.170 0 0
Acyl chain remodelling of PG R-HSA-1482925 6.768122e-01 0.170 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 6.768122e-01 0.170 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 6.796818e-01 0.168 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 6.796818e-01 0.168 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.796818e-01 0.168 0 0
Diseases of DNA repair R-HSA-9675135 6.796818e-01 0.168 0 0
Macroautophagy R-HSA-1632852 6.820701e-01 0.166 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.824003e-01 0.166 0 0
SARS-CoV Infections R-HSA-9679506 6.865342e-01 0.163 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.905632e-01 0.161 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 6.905632e-01 0.161 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 6.905632e-01 0.161 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 6.905632e-01 0.161 0 0
Ribavirin ADME R-HSA-9755088 6.905632e-01 0.161 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 6.984931e-01 0.156 0 0
Intraflagellar transport R-HSA-5620924 6.987486e-01 0.156 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 7.037299e-01 0.153 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 7.037299e-01 0.153 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.037299e-01 0.153 0 0
Signaling by KIT in disease R-HSA-9669938 7.037299e-01 0.153 0 0
mTORC1-mediated signalling R-HSA-166208 7.037299e-01 0.153 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 7.037299e-01 0.153 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 7.037299e-01 0.153 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.037299e-01 0.153 0 0
UCH proteinases R-HSA-5689603 7.061092e-01 0.151 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 7.079239e-01 0.150 0 0
tRNA processing R-HSA-72306 7.124238e-01 0.147 0 0
Formation of the cornified envelope R-HSA-6809371 7.147949e-01 0.146 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 7.163371e-01 0.145 0 0
Formation of the ureteric bud R-HSA-9830674 7.163371e-01 0.145 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 7.163371e-01 0.145 0 0
Signaling by FGFR2 in disease R-HSA-5655253 7.168647e-01 0.145 0 0
Infectious disease R-HSA-5663205 7.191129e-01 0.143 0 0
ER to Golgi Anterograde Transport R-HSA-199977 7.208977e-01 0.142 0 0
Nuclear Receptor transcription pathway R-HSA-383280 7.208980e-01 0.142 0 0
Integrin cell surface interactions R-HSA-216083 7.208980e-01 0.142 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 7.223780e-01 0.141 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 7.255744e-01 0.139 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 7.255744e-01 0.139 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.284086e-01 0.138 0 0
Complex III assembly R-HSA-9865881 7.284086e-01 0.138 0 0
TNFs bind their physiological receptors R-HSA-5669034 7.284086e-01 0.138 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.284086e-01 0.138 0 0
SARS-CoV-2 Infection R-HSA-9694516 7.297575e-01 0.137 0 0
Gastrulation R-HSA-9758941 7.313645e-01 0.136 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 7.340563e-01 0.134 0 0
Neurexins and neuroligins R-HSA-6794361 7.340563e-01 0.134 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 7.340563e-01 0.134 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 7.340563e-01 0.134 0 0
MITF-M-dependent gene expression R-HSA-9856651 7.364930e-01 0.133 0 0
Platelet degranulation R-HSA-114608 7.375013e-01 0.132 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.399670e-01 0.131 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 7.399670e-01 0.131 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 7.399670e-01 0.131 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.399670e-01 0.131 0 0
G protein gated Potassium channels R-HSA-1296059 7.399670e-01 0.131 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.399670e-01 0.131 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 7.399670e-01 0.131 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 7.399670e-01 0.131 0 0
Defects in cobalamin (B12) metabolism R-HSA-3296469 7.399670e-01 0.131 0 0
Laminin interactions R-HSA-3000157 7.399670e-01 0.131 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 7.399670e-01 0.131 0 0
RSV-host interactions R-HSA-9833110 7.409171e-01 0.130 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.419862e-01 0.130 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 7.423141e-01 0.129 0 0
Nucleotide Excision Repair R-HSA-5696398 7.468842e-01 0.127 0 0
Translation initiation complex formation R-HSA-72649 7.503515e-01 0.125 0 0
MET activates PTK2 signaling R-HSA-8874081 7.510343e-01 0.124 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 7.510343e-01 0.124 0 0
Suppression of phagosomal maturation R-HSA-9637687 7.510343e-01 0.124 0 0
G alpha (z) signalling events R-HSA-418597 7.581723e-01 0.120 0 0
Synthesis of DNA R-HSA-69239 7.585026e-01 0.120 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.616311e-01 0.118 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 7.616311e-01 0.118 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 7.616311e-01 0.118 0 0
Triglyceride biosynthesis R-HSA-75109 7.616311e-01 0.118 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 7.616311e-01 0.118 0 0
Maturation of hRSV A proteins R-HSA-9828806 7.616311e-01 0.118 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 7.617880e-01 0.118 0 0
Antigen processing-Cross presentation R-HSA-1236975 7.641551e-01 0.117 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 7.657804e-01 0.116 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 7.657804e-01 0.116 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.717775e-01 0.113 0 0
HIV elongation arrest and recovery R-HSA-167287 7.717775e-01 0.113 0 0
Pausing and recovery of HIV elongation R-HSA-167290 7.717775e-01 0.113 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 7.717775e-01 0.113 0 0
Insulin receptor recycling R-HSA-77387 7.717775e-01 0.113 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 7.717775e-01 0.113 0 0
Pyrimidine salvage R-HSA-73614 7.717775e-01 0.113 0 0
Inflammasomes R-HSA-622312 7.717775e-01 0.113 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.740031e-01 0.111 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 7.742925e-01 0.111 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.742925e-01 0.111 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.803740e-01 0.108 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 7.803740e-01 0.108 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.814926e-01 0.107 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 7.814926e-01 0.107 0 0
Platelet calcium homeostasis R-HSA-418360 7.814926e-01 0.107 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.814926e-01 0.107 0 0
Inositol phosphate metabolism R-HSA-1483249 7.857377e-01 0.105 0 0
Extension of Telomeres R-HSA-180786 7.873676e-01 0.104 0 0
Peroxisomal protein import R-HSA-9033241 7.873676e-01 0.104 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 7.873676e-01 0.104 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 7.873676e-01 0.104 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.907948e-01 0.102 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.907948e-01 0.102 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.907948e-01 0.102 0 0
Neurotransmitter clearance R-HSA-112311 7.907948e-01 0.102 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.907948e-01 0.102 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 7.907948e-01 0.102 0 0
GABA receptor activation R-HSA-977443 7.941644e-01 0.100 0 0
Glutathione conjugation R-HSA-156590 7.941644e-01 0.100 0 0
ER-Phagosome pathway R-HSA-1236974 7.976861e-01 0.098 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 7.997014e-01 0.097 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.997014e-01 0.097 0 0
Molecules associated with elastic fibres R-HSA-2129379 7.997014e-01 0.097 0 0
Collagen degradation R-HSA-1442490 8.007685e-01 0.096 0 0
Selenoamino acid metabolism R-HSA-2408522 8.010216e-01 0.096 0 0
Unfolded Protein Response (UPR) R-HSA-381119 8.064933e-01 0.093 0 0
Signaling by PDGF R-HSA-186797 8.071840e-01 0.093 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.082294e-01 0.092 0 0
Signaling by WNT in cancer R-HSA-4791275 8.082294e-01 0.092 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 8.082294e-01 0.092 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 8.163948e-01 0.088 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 8.163948e-01 0.088 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 8.163948e-01 0.088 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 8.163948e-01 0.088 0 0
Nuclear RNA decay R-HSA-9930044 8.163948e-01 0.088 0 0
Activation of ATR in response to replication stress R-HSA-176187 8.163948e-01 0.088 0 0
FGFR1 mutant receptor activation R-HSA-1839124 8.163948e-01 0.088 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 8.163948e-01 0.088 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 8.190178e-01 0.087 0 0
FCGR activation R-HSA-2029481 8.240423e-01 0.084 0 0
Resolution of D-Loop Structures R-HSA-5693537 8.242130e-01 0.084 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.242130e-01 0.084 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.242130e-01 0.084 0 0
Vpu mediated degradation of CD4 R-HSA-180534 8.242130e-01 0.084 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 8.310413e-01 0.080 0 0
Dual Incision in GG-NER R-HSA-5696400 8.316988e-01 0.080 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.316988e-01 0.080 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.316988e-01 0.080 0 0
eNOS activation R-HSA-203615 8.316988e-01 0.080 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 8.316988e-01 0.080 0 0
Gap junction assembly R-HSA-190861 8.316988e-01 0.080 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.316988e-01 0.080 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 8.370172e-01 0.077 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 8.388662e-01 0.076 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 8.388662e-01 0.076 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.388662e-01 0.076 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.388662e-01 0.076 0 0
Regulation of Apoptosis R-HSA-169911 8.388662e-01 0.076 0 0
PERK regulates gene expression R-HSA-381042 8.388662e-01 0.076 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 8.388662e-01 0.076 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 8.419438e-01 0.075 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.457288e-01 0.073 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 8.457288e-01 0.073 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.457288e-01 0.073 0 0
Glycosphingolipid transport R-HSA-9845576 8.457288e-01 0.073 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.457288e-01 0.073 0 0
SARS-CoV-1 Infection R-HSA-9678108 8.459825e-01 0.073 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 8.470580e-01 0.072 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 8.474106e-01 0.072 0 0
Regulation of insulin secretion R-HSA-422356 8.517471e-01 0.070 0 0
Post-translational protein modification R-HSA-597592 8.518567e-01 0.070 0 0
Degradation of AXIN R-HSA-4641257 8.522995e-01 0.069 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 8.522995e-01 0.069 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 8.522995e-01 0.069 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 8.571041e-01 0.067 0 0
Metabolism of porphyrins R-HSA-189445 8.571041e-01 0.067 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 8.585908e-01 0.066 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 8.585908e-01 0.066 0 0
Elastic fibre formation R-HSA-1566948 8.585908e-01 0.066 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.585908e-01 0.066 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.602712e-01 0.065 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 8.603824e-01 0.065 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 8.646144e-01 0.063 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 8.646144e-01 0.063 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.646144e-01 0.063 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 8.646144e-01 0.063 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 8.664606e-01 0.062 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 8.703818e-01 0.060 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 8.703818e-01 0.060 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.703818e-01 0.060 0 0
HIV Transcription Elongation R-HSA-167169 8.703818e-01 0.060 0 0
Aggrephagy R-HSA-9646399 8.703818e-01 0.060 0 0
Attenuation phase R-HSA-3371568 8.703818e-01 0.060 0 0
Glycogen metabolism R-HSA-8982491 8.703818e-01 0.060 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 8.703818e-01 0.060 0 0
Signaling by FGFR in disease R-HSA-1226099 8.709251e-01 0.060 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 8.709251e-01 0.060 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 8.752520e-01 0.058 0 0
Centrosome maturation R-HSA-380287 8.752520e-01 0.058 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.752520e-01 0.058 0 0
Opioid Signalling R-HSA-111885 8.755720e-01 0.058 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 8.759038e-01 0.058 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 8.759038e-01 0.058 0 0
Maturation of spike protein R-HSA-9694548 8.759038e-01 0.058 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 8.759038e-01 0.058 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 8.786888e-01 0.056 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.811909e-01 0.055 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.811909e-01 0.055 0 0
Degradation of CRY and PER proteins R-HSA-9932298 8.811909e-01 0.055 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.811909e-01 0.055 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.811909e-01 0.055 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.811909e-01 0.055 0 0
Interferon gamma signaling R-HSA-877300 8.820953e-01 0.054 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 8.835072e-01 0.054 0 0
Degradation of the extracellular matrix R-HSA-1474228 8.839706e-01 0.054 0 0
Platelet homeostasis R-HSA-418346 8.861624e-01 0.052 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.862531e-01 0.052 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.862531e-01 0.052 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.862531e-01 0.052 0 0
Interleukin-10 signaling R-HSA-6783783 8.874427e-01 0.052 0 0
SLC-mediated transport of organic anions R-HSA-9955298 8.874427e-01 0.052 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 8.910999e-01 0.050 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 8.910999e-01 0.050 0 0
Response of Mtb to phagocytosis R-HSA-9637690 8.910999e-01 0.050 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 8.912546e-01 0.050 0 0
Surfactant metabolism R-HSA-5683826 8.957404e-01 0.048 0 0
Proteasome assembly R-HSA-9907900 8.957404e-01 0.048 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 8.957404e-01 0.048 0 0
Neddylation R-HSA-8951664 8.981149e-01 0.047 0 0
Integration of energy metabolism R-HSA-163685 8.986237e-01 0.046 0 0
Fanconi Anemia Pathway R-HSA-6783310 9.001835e-01 0.046 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.001835e-01 0.046 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.001835e-01 0.046 0 0
SLC transporter disorders R-HSA-5619102 9.034082e-01 0.044 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 9.044375e-01 0.044 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.044375e-01 0.044 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.044375e-01 0.044 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.044375e-01 0.044 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.049580e-01 0.043 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.053337e-01 0.043 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.072414e-01 0.042 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.085104e-01 0.042 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.085104e-01 0.042 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.085104e-01 0.042 0 0
G alpha (s) signalling events R-HSA-418555 9.149567e-01 0.039 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.161436e-01 0.038 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.173289e-01 0.037 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.184276e-01 0.037 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.231407e-01 0.035 0 0
The phototransduction cascade R-HSA-2514856 9.231407e-01 0.035 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 9.232911e-01 0.035 0 0
Rab regulation of trafficking R-HSA-9007101 9.233102e-01 0.035 0 0
Mitochondrial biogenesis R-HSA-1592230 9.233102e-01 0.035 0 0
G alpha (q) signalling events R-HSA-416476 9.256614e-01 0.034 0 0
Downstream TCR signaling R-HSA-202424 9.285274e-01 0.032 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.295548e-01 0.032 0 0
Nucleotide biosynthesis R-HSA-8956320 9.295548e-01 0.032 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.350888e-01 0.029 0 0
Paracetamol ADME R-HSA-9753281 9.354343e-01 0.029 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 9.381876e-01 0.028 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.381876e-01 0.028 0 0
Extracellular matrix organization R-HSA-1474244 9.394530e-01 0.027 0 0
Collagen formation R-HSA-1474290 9.401792e-01 0.027 0 0
Dectin-2 family R-HSA-5621480 9.408237e-01 0.026 0 0
Dual incision in TC-NER R-HSA-6782135 9.433475e-01 0.025 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.433475e-01 0.025 0 0
Triglyceride metabolism R-HSA-8979227 9.457638e-01 0.024 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.462796e-01 0.024 0 0
RAB geranylgeranylation R-HSA-8873719 9.480772e-01 0.023 0 0
Metabolism of polyamines R-HSA-351202 9.480772e-01 0.023 0 0
tRNA Aminoacylation R-HSA-379724 9.480772e-01 0.023 0 0
Endogenous sterols R-HSA-211976 9.502921e-01 0.022 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.524126e-01 0.021 0 0
ABC-family proteins mediated transport R-HSA-382556 9.534970e-01 0.021 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.544428e-01 0.020 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.563865e-01 0.019 0 0
Xenobiotics R-HSA-211981 9.563865e-01 0.019 0 0
AURKA Activation by TPX2 R-HSA-8854518 9.600290e-01 0.018 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 9.617346e-01 0.017 0 0
Transcription of the HIV genome R-HSA-167172 9.633676e-01 0.016 0 0
GPCR downstream signalling R-HSA-388396 9.649625e-01 0.015 0 0
COPII-mediated vesicle transport R-HSA-204005 9.664278e-01 0.015 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.664278e-01 0.015 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.669854e-01 0.015 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.669854e-01 0.015 0 0
Keratinization R-HSA-6805567 9.678075e-01 0.014 0 0
ECM proteoglycans R-HSA-3000178 9.678607e-01 0.014 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.678607e-01 0.014 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.678607e-01 0.014 0 0
Metabolism of cofactors R-HSA-8978934 9.678607e-01 0.014 0 0
TCR signaling R-HSA-202403 9.688726e-01 0.014 0 0
Purine catabolism R-HSA-74259 9.692326e-01 0.014 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.692326e-01 0.014 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.716244e-01 0.013 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.718034e-01 0.012 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.730072e-01 0.012 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.746410e-01 0.011 0 0
Translation of Structural Proteins R-HSA-9694635 9.752631e-01 0.011 0 0
Cholesterol biosynthesis R-HSA-191273 9.763194e-01 0.010 0 0
ABC transporter disorders R-HSA-5619084 9.763194e-01 0.010 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.773306e-01 0.010 0 0
Peptide hormone metabolism R-HSA-2980736 9.776890e-01 0.010 0 0
Signaling by GPCR R-HSA-372790 9.780465e-01 0.010 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.817756e-01 0.008 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.853500e-01 0.006 0 0
Metabolism of nucleotides R-HSA-15869 9.865334e-01 0.006 0 0
Neurotransmitter release cycle R-HSA-112310 9.865753e-01 0.006 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.882241e-01 0.005 0 0
Transport of small molecules R-HSA-382551 9.891271e-01 0.005 0 0
Metabolism of proteins R-HSA-392499 9.914158e-01 0.004 0 0
Drug ADME R-HSA-9748784 9.922207e-01 0.003 0 0
Protein localization R-HSA-9609507 9.951176e-01 0.002 0 0
Antimicrobial peptides R-HSA-6803157 9.952976e-01 0.002 0 0
G alpha (i) signalling events R-HSA-418594 9.954147e-01 0.002 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.958425e-01 0.002 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.972186e-01 0.001 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.973866e-01 0.001 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.974517e-01 0.001 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.974517e-01 0.001 0 0
Translation R-HSA-72766 9.974796e-01 0.001 0 0
Regulation of Complement cascade R-HSA-977606 9.976654e-01 0.001 0 0
Nucleotide catabolism R-HSA-8956319 9.981245e-01 0.001 0 0
Sensory perception of taste R-HSA-9717189 9.983555e-01 0.001 0 0
Diseases of glycosylation R-HSA-3781865 9.986022e-01 0.001 0 0
Peptide ligand-binding receptors R-HSA-375276 9.987084e-01 0.001 0 0
Cilium Assembly R-HSA-5617833 9.988974e-01 0.000 0 0
Organelle biogenesis and maintenance R-HSA-1852241 9.990582e-01 0.000 0 0
Complement cascade R-HSA-166658 9.991844e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.992529e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.993450e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.994000e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.996126e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.996894e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.997442e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.998167e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.998514e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.998654e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999333e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999631e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999794e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999822e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999829e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999958e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999978e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999979e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999991e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999995e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999999e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.110223e-16 15.955 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.110223e-16 15.955 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.110223e-16 15.955 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.110223e-16 15.955 0 0
Eukaryotic Translation Elongation R-HSA-156842 1.110223e-16 15.955 0 0
HSF1-dependent transactivation R-HSA-3371571 1.110223e-16 15.955 0 0
HSF1 activation R-HSA-3371511 1.110223e-16 15.955 0 0
Attenuation phase R-HSA-3371568 1.110223e-16 15.955 0 0
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Cell-Cell communication R-HSA-1500931 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 2.220446e-16 15.654 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 3.330669e-16 15.477 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 4.440892e-16 15.353 0 0
Aggrephagy R-HSA-9646399 8.881784e-16 15.051 0 0
Cell Cycle R-HSA-1640170 8.881784e-16 15.051 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.221245e-15 14.913 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.665335e-15 14.778 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.887379e-15 14.724 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.887379e-15 14.724 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.108624e-15 14.507 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.885781e-15 14.411 0 0
Cell Cycle, Mitotic R-HSA-69278 4.996004e-15 14.301 0 0
Cell junction organization R-HSA-446728 1.065814e-14 13.972 0 0
Ribosome-associated quality control R-HSA-9948299 1.154632e-14 13.938 0 0
Influenza Infection R-HSA-168255 2.542411e-14 13.595 0 0
G2/M Checkpoints R-HSA-69481 3.053113e-14 13.515 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 3.153033e-14 13.501 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 4.318768e-14 13.365 0 0
Viral Infection Pathways R-HSA-9824446 4.984901e-14 13.302 0 0
PKR-mediated signaling R-HSA-9833482 8.426593e-14 13.074 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.088019e-13 12.963 0 0
Peptide chain elongation R-HSA-156902 1.117995e-13 12.952 0 0
Apoptosis R-HSA-109581 1.640910e-13 12.785 0 0
Signaling by ROBO receptors R-HSA-376176 1.919576e-13 12.717 0 0
Programmed Cell Death R-HSA-5357801 2.906564e-13 12.537 0 0
Developmental Biology R-HSA-1266738 4.957146e-13 12.305 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 6.756817e-13 12.170 0 0
Selective autophagy R-HSA-9663891 7.340795e-13 12.134 0 0
Metabolism of RNA R-HSA-8953854 7.547296e-13 12.122 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 9.539036e-13 12.020 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 9.539036e-13 12.020 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.026290e-12 11.989 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.026290e-12 11.989 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.247780e-12 11.904 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 1.433853e-12 11.843 0 0
Translation initiation complex formation R-HSA-72649 1.672884e-12 11.777 0 0
Cytokine Signaling in Immune system R-HSA-1280215 2.650768e-12 11.577 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.663314e-12 11.575 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 3.003819e-12 11.522 0 0
Chaperonin-mediated protein folding R-HSA-390466 3.727907e-12 11.429 0 0
Regulation of CDH1 Function R-HSA-9764561 3.993916e-12 11.399 0 0
Transport of connexons to the plasma membrane R-HSA-190872 4.767187e-12 11.322 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.106027e-12 11.292 0 0
Eukaryotic Translation Termination R-HSA-72764 5.106027e-12 11.292 0 0
SARS-CoV-1 Infection R-HSA-9678108 6.064815e-12 11.217 0 0
Adherens junctions interactions R-HSA-418990 6.488921e-12 11.188 0 0
Autophagy R-HSA-9612973 6.763590e-12 11.170 0 0
Cellular response to starvation R-HSA-9711097 9.088175e-12 11.042 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.001854e-11 10.999 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.009925e-11 10.996 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.135614e-11 10.945 0 0
Cell Cycle Checkpoints R-HSA-69620 1.240041e-11 10.907 0 0
Protein folding R-HSA-391251 1.328548e-11 10.877 0 0
Macroautophagy R-HSA-1632852 1.283185e-11 10.892 0 0
Selenocysteine synthesis R-HSA-2408557 1.672817e-11 10.777 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.762779e-11 10.754 0 0
Viral mRNA Translation R-HSA-192823 2.442624e-11 10.612 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.355882e-11 10.628 0 0
G2/M Transition R-HSA-69275 2.666634e-11 10.574 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.451850e-11 10.462 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.175649e-11 10.379 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.104117e-11 10.148 0 0
Cell-cell junction organization R-HSA-421270 7.572754e-11 10.121 0 0
L1CAM interactions R-HSA-373760 7.886958e-11 10.103 0 0
Recycling pathway of L1 R-HSA-437239 1.105684e-10 9.956 0 0
Post NMDA receptor activation events R-HSA-438064 1.344618e-10 9.871 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.546595e-10 9.811 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.638406e-10 9.786 0 0
Infectious disease R-HSA-5663205 1.714289e-10 9.766 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.839032e-10 9.735 0 0
Gap junction trafficking and regulation R-HSA-157858 1.939426e-10 9.712 0 0
Translation R-HSA-72766 2.244916e-10 9.649 0 0
Mitotic Anaphase R-HSA-68882 2.861302e-10 9.543 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.198349e-10 9.495 0 0
HCMV Early Events R-HSA-9609690 3.632279e-10 9.440 0 0
Gap junction trafficking R-HSA-190828 3.680057e-10 9.434 0 0
Selenoamino acid metabolism R-HSA-2408522 3.857383e-10 9.414 0 0
Interferon Signaling R-HSA-913531 4.260196e-10 9.371 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 4.549087e-10 9.342 0 0
Signaling by ERBB2 R-HSA-1227986 4.549325e-10 9.342 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.447513e-10 9.191 0 0
Apoptotic execution phase R-HSA-75153 6.447513e-10 9.191 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.472935e-10 9.072 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.046316e-09 8.980 0 0
Signal Transduction R-HSA-162582 1.367543e-09 8.864 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.498930e-09 8.824 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.849559e-09 8.733 0 0
Assembly of the pre-replicative complex R-HSA-68867 2.680139e-09 8.572 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 2.861248e-09 8.543 0 0
Mitotic Prophase R-HSA-68875 3.306007e-09 8.481 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 4.625827e-09 8.335 0 0
Separation of Sister Chromatids R-HSA-2467813 6.076354e-09 8.216 0 0
Processing of DNA double-strand break ends R-HSA-5693607 6.124310e-09 8.213 0 0
Gap junction assembly R-HSA-190861 7.577347e-09 8.120 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 8.720532e-09 8.059 0 0
HCMV Infection R-HSA-9609646 9.065700e-09 8.043 0 0
Signaling by RAF1 mutants R-HSA-9656223 9.339599e-09 8.030 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.963927e-09 8.002 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.210546e-08 7.917 0 0
Interleukin-12 signaling R-HSA-9020591 1.318281e-08 7.880 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.364158e-08 7.865 0 0
Immune System R-HSA-168256 1.744394e-08 7.758 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 2.177409e-08 7.662 0 0
Diseases of programmed cell death R-HSA-9645723 2.476246e-08 7.606 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 2.530128e-08 7.597 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.665888e-08 7.574 0 0
Signaling downstream of RAS mutants R-HSA-9649948 3.281714e-08 7.484 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 3.281714e-08 7.484 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 3.281714e-08 7.484 0 0
Signaling by RAS mutants R-HSA-6802949 3.281714e-08 7.484 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 3.407837e-08 7.468 0 0
MAPK family signaling cascades R-HSA-5683057 3.809847e-08 7.419 0 0
Mitotic Prometaphase R-HSA-68877 4.447909e-08 7.352 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 4.719699e-08 7.326 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 4.991493e-08 7.302 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 5.036213e-08 7.298 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.370577e-08 7.270 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 6.028449e-08 7.220 0 0
Platelet activation, signaling and aggregation R-HSA-76002 7.291786e-08 7.137 0 0
RAF/MAP kinase cascade R-HSA-5673001 8.310453e-08 7.080 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 8.863590e-08 7.052 0 0
Interleukin-12 family signaling R-HSA-447115 1.025458e-07 6.989 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.186716e-07 6.926 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.317814e-07 6.880 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.508710e-07 6.821 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.542337e-07 6.812 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.662990e-07 6.779 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.801387e-07 6.744 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.908536e-07 6.719 0 0
Homology Directed Repair R-HSA-5693538 1.934677e-07 6.713 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 1.891012e-07 6.723 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 2.015497e-07 6.696 0 0
Hedgehog 'off' state R-HSA-5610787 2.081879e-07 6.682 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.129034e-07 6.672 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.504915e-07 6.601 0 0
EPH-Ephrin signaling R-HSA-2682334 2.545569e-07 6.594 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 2.644805e-07 6.578 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.744056e-07 6.562 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.808257e-07 6.552 0 0
DNA Replication R-HSA-69306 3.251916e-07 6.488 0 0
Cilium Assembly R-HSA-5617833 3.663817e-07 6.436 0 0
Packaging Of Telomere Ends R-HSA-171306 3.824354e-07 6.417 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 3.824354e-07 6.417 0 0
DNA Double Strand Break Response R-HSA-5693606 3.906001e-07 6.408 0 0
Degradation of CDH1 R-HSA-9766229 4.025923e-07 6.395 0 0
Cellular Senescence R-HSA-2559583 4.648048e-07 6.333 0 0
Signaling by VEGF R-HSA-194138 5.102557e-07 6.292 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 5.943380e-07 6.226 0 0
Gene Silencing by RNA R-HSA-211000 6.057368e-07 6.218 0 0
DNA methylation R-HSA-5334118 6.751999e-07 6.171 0 0
PRC2 methylates histones and DNA R-HSA-212300 7.287349e-07 6.137 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 7.287349e-07 6.137 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 7.323364e-07 6.135 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 7.638587e-07 6.117 0 0
Amyloid fiber formation R-HSA-977225 7.679081e-07 6.115 0 0
Meiotic synapsis R-HSA-1221632 8.869021e-07 6.052 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 9.185750e-07 6.037 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 9.229677e-07 6.035 0 0
Cleavage of the damaged purine R-HSA-110331 9.229677e-07 6.035 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.052333e-06 5.978 0 0
Nucleosome assembly R-HSA-774815 1.052333e-06 5.978 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.078431e-06 5.967 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.142426e-06 5.942 0 0
Depurination R-HSA-73927 1.161756e-06 5.935 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.195764e-06 5.922 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.219465e-06 5.914 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.286368e-06 5.891 0 0
Disease R-HSA-1643685 1.327575e-06 5.877 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.380358e-06 5.860 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.431422e-06 5.844 0 0
Protein ubiquitination R-HSA-8852135 1.433826e-06 5.844 0 0
rRNA processing R-HSA-72312 1.553221e-06 5.809 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.808726e-06 5.743 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.808726e-06 5.743 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.910867e-06 5.719 0 0
SARS-CoV-2 Infection R-HSA-9694516 2.071790e-06 5.684 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.289682e-06 5.640 0 0
Signaling by Hedgehog R-HSA-5358351 2.606690e-06 5.584 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 2.669600e-06 5.574 0 0
MAP2K and MAPK activation R-HSA-5674135 2.755513e-06 5.560 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 2.749623e-06 5.561 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.749623e-06 5.561 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.069929e-06 5.513 0 0
Kinesins R-HSA-983189 3.069929e-06 5.513 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 3.039210e-06 5.517 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 3.118978e-06 5.506 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 3.353404e-06 5.475 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 3.627731e-06 5.440 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.724206e-06 5.429 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.825936e-06 5.417 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.955437e-06 5.403 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 3.997276e-06 5.398 0 0
Defective pyroptosis R-HSA-9710421 4.114906e-06 5.386 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 4.673845e-06 5.330 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 4.859073e-06 5.313 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 4.941874e-06 5.306 0 0
mRNA Splicing - Major Pathway R-HSA-72163 4.945550e-06 5.306 0 0
EPHB-mediated forward signaling R-HSA-3928662 4.993427e-06 5.302 0 0
Host Interactions of HIV factors R-HSA-162909 5.436137e-06 5.265 0 0
Adaptive Immune System R-HSA-1280218 5.708063e-06 5.244 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 5.873709e-06 5.231 0 0
SARS-CoV Infections R-HSA-9679506 6.430410e-06 5.192 0 0
Ub-specific processing proteases R-HSA-5689880 7.716115e-06 5.113 0 0
Signaling by Interleukins R-HSA-449147 7.877342e-06 5.104 0 0
Co-inhibition by PD-1 R-HSA-389948 7.978966e-06 5.098 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 8.522099e-06 5.069 0 0
mRNA Splicing R-HSA-72172 1.171084e-05 4.931 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.277395e-05 4.894 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.307330e-05 4.884 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.307330e-05 4.884 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.407329e-05 4.852 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.569745e-05 4.804 0 0
Meiotic recombination R-HSA-912446 1.724226e-05 4.763 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.893792e-05 4.723 0 0
Depyrimidination R-HSA-73928 1.893792e-05 4.723 0 0
Nephrin family interactions R-HSA-373753 1.963193e-05 4.707 0 0
Gene expression (Transcription) R-HSA-74160 1.979490e-05 4.703 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.994690e-05 4.700 0 0
Orc1 removal from chromatin R-HSA-68949 2.027974e-05 4.693 0 0
Signaling by WNT R-HSA-195721 2.041815e-05 4.690 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.102453e-05 4.677 0 0
Signaling by PTK6 R-HSA-8848021 2.305484e-05 4.637 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 2.305484e-05 4.637 0 0
Meiosis R-HSA-1500620 2.397141e-05 4.620 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.685880e-05 4.571 0 0
Platelet degranulation R-HSA-114608 2.722526e-05 4.565 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 2.777896e-05 4.556 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.834407e-05 4.548 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 3.128907e-05 4.505 0 0
COPI-mediated anterograde transport R-HSA-6807878 3.190747e-05 4.496 0 0
HDACs deacetylate histones R-HSA-3214815 3.235889e-05 4.490 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 3.456483e-05 4.461 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 3.456483e-05 4.461 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 3.456483e-05 4.461 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 3.456483e-05 4.461 0 0
Metabolism of proteins R-HSA-392499 3.506270e-05 4.455 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.506296e-05 4.455 0 0
Generic Transcription Pathway R-HSA-212436 3.590633e-05 4.445 0 0
Hemostasis R-HSA-109582 3.684058e-05 4.434 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.441945e-05 4.352 0 0
mTORC1-mediated signalling R-HSA-166208 4.334332e-05 4.363 0 0
RNA Polymerase I Transcription R-HSA-73864 4.017550e-05 4.396 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 4.582008e-05 4.339 0 0
TCF dependent signaling in response to WNT R-HSA-201681 4.894918e-05 4.310 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 5.025012e-05 4.299 0 0
Intraflagellar transport R-HSA-5620924 5.207780e-05 4.283 0 0
Signaling by NOTCH R-HSA-157118 5.305108e-05 4.275 0 0
Deubiquitination R-HSA-5688426 5.422167e-05 4.266 0 0
MHC class II antigen presentation R-HSA-2132295 5.516572e-05 4.258 0 0
Neutrophil degranulation R-HSA-6798695 5.653603e-05 4.248 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 5.904577e-05 4.229 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 6.974000e-05 4.157 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 7.010465e-05 4.154 0 0
Organelle biogenesis and maintenance R-HSA-1852241 7.084220e-05 4.150 0 0
Estrogen-dependent gene expression R-HSA-9018519 7.218774e-05 4.142 0 0
Long-term potentiation R-HSA-9620244 8.726614e-05 4.059 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 8.799763e-05 4.056 0 0
Striated Muscle Contraction R-HSA-390522 9.030787e-05 4.044 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 9.030787e-05 4.044 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 9.915460e-05 4.004 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 9.915460e-05 4.004 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.082400e-04 3.966 0 0
Signaling by ALK in cancer R-HSA-9700206 1.082400e-04 3.966 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 1.085224e-04 3.964 0 0
ESR-mediated signaling R-HSA-8939211 1.092910e-04 3.961 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 1.270852e-04 3.896 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 1.297165e-04 3.887 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 1.333434e-04 3.875 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.333434e-04 3.875 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.333434e-04 3.875 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.448156e-04 3.839 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 1.555294e-04 3.808 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 1.555294e-04 3.808 0 0
RNA Polymerase II Transcription R-HSA-73857 1.630770e-04 3.788 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.713131e-04 3.766 0 0
Base Excision Repair R-HSA-73884 1.721891e-04 3.764 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.735708e-04 3.761 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 1.825670e-04 3.739 0 0
Degradation of DVL R-HSA-4641258 1.825670e-04 3.739 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.854499e-04 3.732 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.854499e-04 3.732 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 2.300784e-04 3.638 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 2.300784e-04 3.638 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 1.978557e-04 3.704 0 0
Late endosomal microautophagy R-HSA-9615710 1.978557e-04 3.704 0 0
G1/S Transition R-HSA-69206 2.196192e-04 3.658 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 2.190676e-04 3.659 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 2.326272e-04 3.633 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.326272e-04 3.633 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.887528e-04 3.724 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.300784e-04 3.638 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 2.328117e-04 3.633 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 2.328117e-04 3.633 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.386219e-04 3.622 0 0
Activation of BH3-only proteins R-HSA-114452 2.386219e-04 3.622 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 2.522301e-04 3.598 0 0
Membrane Trafficking R-HSA-199991 2.550325e-04 3.593 0 0
Cellular response to chemical stress R-HSA-9711123 2.695026e-04 3.569 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 2.860220e-04 3.544 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 2.916744e-04 3.535 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 2.920890e-04 3.534 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 2.945664e-04 3.531 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 3.114981e-04 3.507 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 3.153347e-04 3.501 0 0
Josephin domain DUBs R-HSA-5689877 3.153347e-04 3.501 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 3.231759e-04 3.491 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.255527e-04 3.487 0 0
Switching of origins to a post-replicative state R-HSA-69052 3.255527e-04 3.487 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 3.426161e-04 3.465 0 0
Muscle contraction R-HSA-397014 3.519413e-04 3.454 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 3.602962e-04 3.443 0 0
Hedgehog ligand biogenesis R-HSA-5358346 3.602962e-04 3.443 0 0
Signaling by NOTCH4 R-HSA-9013694 3.627063e-04 3.440 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 3.673281e-04 3.435 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.724453e-04 3.429 0 0
Semaphorin interactions R-HSA-373755 3.945737e-04 3.404 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 3.945737e-04 3.404 0 0
Degradation of CRY and PER proteins R-HSA-9932298 3.969570e-04 3.401 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 3.969570e-04 3.401 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 3.969570e-04 3.401 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 3.969570e-04 3.401 0 0
Centrosome maturation R-HSA-380287 4.033847e-04 3.394 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 4.033847e-04 3.394 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.033847e-04 3.394 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.039443e-04 3.394 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 4.100693e-04 3.387 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 4.346434e-04 3.362 0 0
Neurodegenerative Diseases R-HSA-8863678 4.346434e-04 3.362 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.406518e-04 3.356 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.406518e-04 3.356 0 0
PECAM1 interactions R-HSA-210990 4.406518e-04 3.356 0 0
MTOR signalling R-HSA-165159 4.582042e-04 3.339 0 0
Vpu mediated degradation of CD4 R-HSA-180534 4.762207e-04 3.322 0 0
Maturation of protein E R-HSA-9683683 4.813240e-04 3.318 0 0
Maturation of protein E R-HSA-9694493 4.813240e-04 3.318 0 0
DNA Repair R-HSA-73894 4.887036e-04 3.311 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 5.270103e-04 3.278 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 5.270103e-04 3.278 0 0
Glycolysis R-HSA-70171 5.316221e-04 3.274 0 0
PCP/CE pathway R-HSA-4086400 5.492583e-04 3.260 0 0
RAF activation R-HSA-5673000 5.586407e-04 3.253 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 5.586407e-04 3.253 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 5.586407e-04 3.253 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 5.753385e-04 3.240 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.916143e-04 3.228 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 6.002463e-04 3.222 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 6.040659e-04 3.219 0 0
Cyclin D associated events in G1 R-HSA-69231 6.040659e-04 3.219 0 0
G1 Phase R-HSA-69236 6.040659e-04 3.219 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 7.953028e-04 3.099 0 0
Signaling by EGFR in Cancer R-HSA-1643713 6.336332e-04 3.198 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 7.996658e-04 3.097 0 0
VLDLR internalisation and degradation R-HSA-8866427 7.996658e-04 3.097 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.087856e-04 3.092 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.087856e-04 3.092 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 6.522275e-04 3.186 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 6.901001e-04 3.161 0 0
Regulation of signaling by CBL R-HSA-912631 7.775783e-04 3.109 0 0
Regulation of Apoptosis R-HSA-169911 6.522275e-04 3.186 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 7.526818e-04 3.123 0 0
Regulation of TP53 Degradation R-HSA-6804757 7.580629e-04 3.120 0 0
p75NTR recruits signalling complexes R-HSA-209543 7.996658e-04 3.097 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 6.699410e-04 3.174 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 6.303775e-04 3.200 0 0
HIV Infection R-HSA-162906 8.122669e-04 3.090 0 0
Transmission across Chemical Synapses R-HSA-112315 8.288236e-04 3.082 0 0
Degradation of AXIN R-HSA-4641257 8.772869e-04 3.057 0 0
Regulation of mitotic cell cycle R-HSA-453276 9.356596e-04 3.029 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 9.356596e-04 3.029 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.011097e-03 2.995 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.033607e-03 2.986 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.044736e-03 2.981 0 0
Regulation of PTEN localization R-HSA-8948747 1.096618e-03 2.960 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.139954e-03 2.943 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.139954e-03 2.943 0 0
Stabilization of p53 R-HSA-69541 1.160748e-03 2.935 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.160748e-03 2.935 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 1.168455e-03 2.932 0 0
Chromosome Maintenance R-HSA-73886 1.211273e-03 2.917 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.244665e-03 2.905 0 0
Telomere Maintenance R-HSA-157579 1.252483e-03 2.902 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.270512e-03 2.896 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.283167e-03 2.892 0 0
TCR signaling R-HSA-202403 1.293659e-03 2.888 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.302489e-03 2.885 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.327549e-03 2.877 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.341514e-03 2.872 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 1.341514e-03 2.872 0 0
Regulation of KIT signaling R-HSA-1433559 1.341514e-03 2.872 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 1.412218e-03 2.850 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.440541e-03 2.841 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 1.452658e-03 2.838 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 1.452658e-03 2.838 0 0
HATs acetylate histones R-HSA-3214847 1.470062e-03 2.833 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.512865e-03 2.820 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 1.512865e-03 2.820 0 0
UCH proteinases R-HSA-5689603 1.513860e-03 2.820 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.551135e-03 2.809 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 1.551135e-03 2.809 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.551135e-03 2.809 0 0
Modulation by Mtb of host immune system R-HSA-9637628 1.551135e-03 2.809 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 1.551135e-03 2.809 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.613071e-03 2.792 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.615350e-03 2.792 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 1.693469e-03 2.771 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.696250e-03 2.771 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.696250e-03 2.771 0 0
p75NTR signals via NF-kB R-HSA-193639 1.696250e-03 2.771 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.718113e-03 2.765 0 0
Cellular response to hypoxia R-HSA-1234174 1.765639e-03 2.753 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.801791e-03 2.744 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 1.801791e-03 2.744 0 0
Regulation of PTEN stability and activity R-HSA-8948751 1.801791e-03 2.744 0 0
Integrin signaling R-HSA-354192 1.949271e-03 2.710 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 1.949271e-03 2.710 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 2.001034e-03 2.699 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 2.007769e-03 2.697 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.115333e-03 2.675 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 2.115333e-03 2.675 0 0
Regulation of BACH1 activity R-HSA-9708530 2.115333e-03 2.675 0 0
Negative regulation of FLT3 R-HSA-9706369 2.115333e-03 2.675 0 0
GP1b-IX-V activation signalling R-HSA-430116 2.122514e-03 2.673 0 0
Response of Mtb to phagocytosis R-HSA-9637690 2.194324e-03 2.659 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.232106e-03 2.651 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.242294e-03 2.649 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 2.242294e-03 2.649 0 0
Regulated Necrosis R-HSA-5218859 2.353740e-03 2.628 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.381331e-03 2.623 0 0
Glucose metabolism R-HSA-70326 2.460063e-03 2.609 0 0
Signaling by EGFR R-HSA-177929 2.475940e-03 2.606 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.475940e-03 2.606 0 0
Reproduction R-HSA-1474165 2.541170e-03 2.595 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.568175e-03 2.590 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 2.605258e-03 2.584 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.605258e-03 2.584 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 2.768499e-03 2.558 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 2.768499e-03 2.558 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 2.824681e-03 2.549 0 0
Pexophagy R-HSA-9664873 2.824681e-03 2.549 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 2.826446e-03 2.549 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.826446e-03 2.549 0 0
PERK regulates gene expression R-HSA-381042 2.929273e-03 2.533 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.081437e-03 2.511 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.089681e-03 2.510 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 3.096365e-03 2.509 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 3.172572e-03 2.499 0 0
ER to Golgi Anterograde Transport R-HSA-199977 3.252878e-03 2.488 0 0
Epigenetic regulation of gene expression R-HSA-212165 3.265606e-03 2.486 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 3.453655e-03 2.462 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.585708e-03 2.445 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 3.652284e-03 2.437 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 5.587950e-03 2.253 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 3.823839e-03 2.418 0 0
Ephrin signaling R-HSA-3928664 3.823839e-03 2.418 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 4.565598e-03 2.341 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 3.781659e-03 2.422 0 0
Signaling by ERBB4 R-HSA-1236394 3.998285e-03 2.398 0 0
Nuclear Receptor transcription pathway R-HSA-383280 5.524482e-03 2.258 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 4.382455e-03 2.358 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 4.382455e-03 2.358 0 0
Translesion Synthesis by POLH R-HSA-110320 4.565598e-03 2.341 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 4.382455e-03 2.358 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 5.005186e-03 2.301 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 4.674910e-03 2.330 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 5.587950e-03 2.253 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 3.781659e-03 2.422 0 0
Interaction between L1 and Ankyrins R-HSA-445095 3.781659e-03 2.422 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 4.361855e-03 2.360 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 5.005186e-03 2.301 0 0
Downstream TCR signaling R-HSA-202424 5.169109e-03 2.287 0 0
Negative regulation of MET activity R-HSA-6807004 5.404325e-03 2.267 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.831074e-03 2.417 0 0
Interleukin-1 signaling R-HSA-9020702 4.750471e-03 2.323 0 0
Gluconeogenesis R-HSA-70263 3.842092e-03 2.415 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.674910e-03 2.330 0 0
NF-kB is activated and signals survival R-HSA-209560 4.674910e-03 2.330 0 0
ABC-family proteins mediated transport R-HSA-382556 4.434337e-03 2.353 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 5.587950e-03 2.253 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 4.247725e-03 2.372 0 0
HCMV Late Events R-HSA-9610379 5.621447e-03 2.250 0 0
Response of endothelial cells to shear stress R-HSA-9860931 5.808134e-03 2.236 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 5.848309e-03 2.233 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 5.848309e-03 2.233 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 5.848309e-03 2.233 0 0
IRAK1 recruits IKK complex R-HSA-937039 5.848309e-03 2.233 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 5.848309e-03 2.233 0 0
FLT3 Signaling R-HSA-9607240 5.973536e-03 2.224 0 0
Smooth Muscle Contraction R-HSA-445355 6.313870e-03 2.200 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.346394e-03 2.197 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 6.346394e-03 2.197 0 0
Signaling by FGFR2 R-HSA-5654738 6.441248e-03 2.191 0 0
Budding and maturation of HIV virion R-HSA-162588 6.496764e-03 2.187 0 0
Intracellular signaling by second messengers R-HSA-9006925 6.512463e-03 2.186 0 0
Regulation of TP53 Activity R-HSA-5633007 6.556357e-03 2.183 0 0
Nucleotide Excision Repair R-HSA-5696398 6.611317e-03 2.180 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 6.978388e-03 2.156 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 7.202984e-03 2.142 0 0
Signaling by Nuclear Receptors R-HSA-9006931 7.307244e-03 2.136 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 7.383777e-03 2.132 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 7.398048e-03 2.131 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 7.398048e-03 2.131 0 0
Assembly Of The HIV Virion R-HSA-175474 7.398048e-03 2.131 0 0
Synthesis of DNA R-HSA-69239 7.499695e-03 2.125 0 0
Vesicle-mediated transport R-HSA-5653656 7.519363e-03 2.124 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 7.703679e-03 2.113 0 0
S Phase R-HSA-69242 7.945245e-03 2.100 0 0
Manipulation of host energy metabolism R-HSA-9636667 7.982722e-03 2.098 0 0
Breakdown of the nuclear lamina R-HSA-352238 7.982722e-03 2.098 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 8.286786e-03 2.082 0 0
TNF signaling R-HSA-75893 8.286786e-03 2.082 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 8.287272e-03 2.082 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 8.565363e-03 2.067 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 8.625754e-03 2.064 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 8.749791e-03 2.058 0 0
NRIF signals cell death from the nucleus R-HSA-205043 8.749791e-03 2.058 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 8.749791e-03 2.058 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 8.936060e-03 2.049 0 0
Innate Immune System R-HSA-168249 9.009125e-03 2.045 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 9.026315e-03 2.044 0 0
Hedgehog 'on' state R-HSA-5632684 9.331280e-03 2.030 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.632568e-03 2.016 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 9.854222e-03 2.006 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 9.941169e-03 2.003 0 0
Somitogenesis R-HSA-9824272 9.941169e-03 2.003 0 0
Recycling of eIF2:GDP R-HSA-72731 1.023273e-02 1.990 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 1.023273e-02 1.990 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 1.023273e-02 1.990 0 0
Dual Incision in GG-NER R-HSA-5696400 1.040705e-02 1.983 0 0
Nuclear import of Rev protein R-HSA-180746 1.040705e-02 1.983 0 0
Mitophagy R-HSA-5205647 1.040705e-02 1.983 0 0
NOD1/2 Signaling Pathway R-HSA-168638 1.040705e-02 1.983 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 1.040705e-02 1.983 0 0
DCC mediated attractive signaling R-HSA-418885 1.049875e-02 1.979 0 0
Translesion synthesis by REV1 R-HSA-110312 1.049875e-02 1.979 0 0
Protein methylation R-HSA-8876725 1.049875e-02 1.979 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.049875e-02 1.979 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 1.049875e-02 1.979 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.067489e-02 1.972 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 1.092183e-02 1.962 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.092183e-02 1.962 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.136647e-02 1.944 0 0
Oncogene Induced Senescence R-HSA-2559585 1.159964e-02 1.936 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.177226e-02 1.929 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 1.197083e-02 1.922 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.245901e-02 1.905 0 0
Translesion synthesis by POLI R-HSA-5656121 1.245901e-02 1.905 0 0
MAP kinase activation R-HSA-450294 1.255404e-02 1.901 0 0
G1/S-Specific Transcription R-HSA-69205 1.288547e-02 1.890 0 0
ER-Phagosome pathway R-HSA-1236974 1.291539e-02 1.889 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.292171e-02 1.889 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.302279e-02 1.885 0 0
Formation of annular gap junctions R-HSA-196025 1.318935e-02 1.880 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.318935e-02 1.880 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.318935e-02 1.880 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.327478e-02 1.877 0 0
Clathrin-mediated endocytosis R-HSA-8856828 1.366793e-02 1.864 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 1.378730e-02 1.861 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.426798e-02 1.846 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.426798e-02 1.846 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.426798e-02 1.846 0 0
DNA Damage Bypass R-HSA-73893 1.428378e-02 1.845 0 0
Suppression of phagosomal maturation R-HSA-9637687 1.450542e-02 1.838 0 0
Translesion synthesis by POLK R-HSA-5655862 1.463882e-02 1.834 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.463882e-02 1.834 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.463882e-02 1.834 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.463882e-02 1.834 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.463882e-02 1.834 0 0
ABC transporter disorders R-HSA-5619084 1.539422e-02 1.813 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.578406e-02 1.802 0 0
Gap junction degradation R-HSA-190873 1.658350e-02 1.780 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.658350e-02 1.780 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.658350e-02 1.780 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.704551e-02 1.768 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 1.704551e-02 1.768 0 0
Signaling by Hippo R-HSA-2028269 1.704551e-02 1.768 0 0
Glycogen storage diseases R-HSA-3229121 1.704551e-02 1.768 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.733630e-02 1.761 0 0
RAS processing R-HSA-9648002 1.733630e-02 1.761 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.831078e-02 1.737 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.832665e-02 1.737 0 0
Neuronal System R-HSA-112316 1.893305e-02 1.723 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.902844e-02 1.721 0 0
GAB1 signalosome R-HSA-180292 1.968551e-02 1.706 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 1.968551e-02 1.706 0 0
Regulation of CDH11 function R-HSA-9762292 2.042128e-02 1.690 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.042128e-02 1.690 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 2.043849e-02 1.690 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.082988e-02 1.681 0 0
FasL/ CD95L signaling R-HSA-75157 2.093133e-02 1.679 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 2.093133e-02 1.679 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.250263e-02 1.648 0 0
Death Receptor Signaling R-HSA-73887 2.250263e-02 1.648 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.256429e-02 1.647 0 0
Rap1 signalling R-HSA-392517 2.256429e-02 1.647 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.256429e-02 1.647 0 0
PTEN Regulation R-HSA-6807070 2.310120e-02 1.636 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.337231e-02 1.631 0 0
Interleukin-17 signaling R-HSA-448424 2.397611e-02 1.620 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 4.307516e-02 1.366 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 2.928899e-02 1.533 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.928899e-02 1.533 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.928899e-02 1.533 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.928899e-02 1.533 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.874275e-02 1.412 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 3.874275e-02 1.412 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 3.874275e-02 1.412 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.460806e-02 1.461 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 4.021801e-02 1.396 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 4.021801e-02 1.396 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 4.021801e-02 1.396 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 4.625754e-02 1.335 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.267470e-02 1.486 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.267470e-02 1.486 0 0
FGFR2 alternative splicing R-HSA-6803529 3.654553e-02 1.437 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.654553e-02 1.437 0 0
Deadenylation of mRNA R-HSA-429947 4.504621e-02 1.346 0 0
G0 and Early G1 R-HSA-1538133 2.776763e-02 1.556 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.053676e-02 1.515 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.347340e-02 1.475 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.985752e-02 1.399 0 0
Dual incision in TC-NER R-HSA-6782135 2.869639e-02 1.542 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 3.277510e-02 1.484 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 4.844672e-02 1.315 0 0
EGFR downregulation R-HSA-182971 2.516352e-02 1.599 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 4.504621e-02 1.346 0 0
HIV Life Cycle R-HSA-162587 2.552499e-02 1.593 0 0
Trafficking of AMPA receptors R-HSA-399719 2.516352e-02 1.599 0 0
Proteasome assembly R-HSA-9907900 2.918255e-02 1.535 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.905565e-02 1.537 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 3.654553e-02 1.437 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 3.874275e-02 1.412 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 3.985752e-02 1.399 0 0
Parasite infection R-HSA-9664407 4.864051e-02 1.313 0 0
Leishmania phagocytosis R-HSA-9664417 4.864051e-02 1.313 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 4.864051e-02 1.313 0 0
Co-stimulation by CD28 R-HSA-389356 3.947968e-02 1.404 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.928899e-02 1.533 0 0
MTF1 activates gene expression R-HSA-5660489 2.928899e-02 1.533 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.267470e-02 1.486 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 3.630921e-02 1.440 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 3.630921e-02 1.440 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 4.142999e-02 1.383 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 4.142999e-02 1.383 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.053676e-02 1.515 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.947968e-02 1.404 0 0
Formation of paraxial mesoderm R-HSA-9793380 3.512848e-02 1.454 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.568645e-02 1.590 0 0
Basigin interactions R-HSA-210991 2.905565e-02 1.537 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.408015e-02 1.467 0 0
Chromatin modifying enzymes R-HSA-3247509 3.556240e-02 1.449 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 4.021801e-02 1.396 0 0
Signalling to ERKs R-HSA-187687 3.985752e-02 1.399 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 4.268873e-02 1.370 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 4.672865e-02 1.330 0 0
MyD88-independent TLR4 cascade R-HSA-166166 4.672865e-02 1.330 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 3.708618e-02 1.431 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 3.874275e-02 1.412 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 2.776763e-02 1.556 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.053676e-02 1.515 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 4.355151e-02 1.361 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.467991e-02 1.608 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.467991e-02 1.608 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.467991e-02 1.608 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 4.467774e-02 1.350 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 2.488226e-02 1.604 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.654553e-02 1.437 0 0
Signaling by KIT in disease R-HSA-9669938 3.654553e-02 1.437 0 0
Syndecan interactions R-HSA-3000170 4.066927e-02 1.391 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 4.527916e-02 1.344 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.267470e-02 1.486 0 0
Antigen processing-Cross presentation R-HSA-1236975 4.268873e-02 1.370 0 0
FLT3 signaling in disease R-HSA-9682385 4.330821e-02 1.363 0 0
Calmodulin induced events R-HSA-111933 4.330821e-02 1.363 0 0
CaM pathway R-HSA-111997 4.330821e-02 1.363 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.518821e-02 1.599 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.568645e-02 1.590 0 0
Signaling by MET R-HSA-6806834 4.355151e-02 1.361 0 0
Regulation of pyruvate metabolism R-HSA-9861718 3.408015e-02 1.467 0 0
Pyruvate metabolism R-HSA-70268 2.849361e-02 1.545 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.905565e-02 1.537 0 0
Signaling by FGFR4 R-HSA-5654743 2.691736e-02 1.570 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 2.905565e-02 1.537 0 0
Signaling by FGFR3 R-HSA-5654741 3.156949e-02 1.501 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 3.890718e-02 1.410 0 0
Signaling by FGFR R-HSA-190236 2.467991e-02 1.608 0 0
Glycogen synthesis R-HSA-3322077 2.568645e-02 1.590 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 4.918297e-02 1.308 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 4.918297e-02 1.308 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.918297e-02 1.308 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 4.962961e-02 1.304 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 4.967590e-02 1.304 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 5.053682e-02 1.296 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 5.073223e-02 1.295 0 0
Post-translational protein modification R-HSA-597592 5.086802e-02 1.294 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 5.102313e-02 1.292 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.271715e-02 1.278 0 0
p38MAPK events R-HSA-171007 5.271715e-02 1.278 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 5.325886e-02 1.274 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 5.447918e-02 1.264 0 0
Metalloprotease DUBs R-HSA-5689901 5.455716e-02 1.263 0 0
Myogenesis R-HSA-525793 5.455716e-02 1.263 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 5.455716e-02 1.263 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 5.470666e-02 1.262 0 0
Plasma lipoprotein clearance R-HSA-8964043 5.470666e-02 1.262 0 0
Signaling by TGFB family members R-HSA-9006936 5.525600e-02 1.258 0 0
Chromatin organization R-HSA-4839726 5.562277e-02 1.255 0 0
FCERI mediated NF-kB activation R-HSA-2871837 5.862392e-02 1.232 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 5.885618e-02 1.230 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.885618e-02 1.230 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 5.958572e-02 1.225 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.958572e-02 1.225 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 5.968810e-02 1.224 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 5.968810e-02 1.224 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 6.036658e-02 1.219 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 6.050736e-02 1.218 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 6.050736e-02 1.218 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 6.050736e-02 1.218 0 0
Nef and signal transduction R-HSA-164944 6.050736e-02 1.218 0 0
G alpha (z) signalling events R-HSA-418597 6.247877e-02 1.204 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 6.318049e-02 1.199 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 6.506617e-02 1.187 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 6.629458e-02 1.179 0 0
Signaling by FGFR1 R-HSA-5654736 6.629458e-02 1.179 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 6.685079e-02 1.175 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 6.685079e-02 1.175 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 6.753195e-02 1.170 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 7.002963e-02 1.155 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 7.002963e-02 1.155 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.068821e-02 1.151 0 0
MITF-M-dependent gene expression R-HSA-9856651 7.229998e-02 1.141 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 7.235063e-02 1.141 0 0
Ca-dependent events R-HSA-111996 7.235063e-02 1.141 0 0
MECP2 regulates transcription factors R-HSA-9022707 7.262062e-02 1.139 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 7.262062e-02 1.139 0 0
Disinhibition of SNARE formation R-HSA-114516 7.262062e-02 1.139 0 0
CHL1 interactions R-HSA-447041 7.262062e-02 1.139 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 7.449871e-02 1.128 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 7.449871e-02 1.128 0 0
RSV-host interactions R-HSA-9833110 7.460230e-02 1.127 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 7.655047e-02 1.116 0 0
Signaling by SCF-KIT R-HSA-1433557 7.719426e-02 1.112 0 0
Interleukin-1 family signaling R-HSA-446652 7.727985e-02 1.112 0 0
Developmental Cell Lineages R-HSA-9734767 8.048286e-02 1.094 0 0
Netrin-1 signaling R-HSA-373752 8.220828e-02 1.085 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 8.264868e-02 1.083 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 8.264868e-02 1.083 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 8.264868e-02 1.083 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 8.429736e-02 1.074 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 8.429736e-02 1.074 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 8.429736e-02 1.074 0 0
Defective Mismatch Repair Associated With MSH3 R-HSA-5632927 8.429736e-02 1.074 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 8.429736e-02 1.074 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 8.429736e-02 1.074 0 0
Hereditary fructose intolerance R-HSA-5657560 8.429736e-02 1.074 0 0
Inhibition of PKR R-HSA-169131 8.429736e-02 1.074 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 8.543398e-02 1.068 0 0
Type I hemidesmosome assembly R-HSA-446107 8.543398e-02 1.068 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 8.543398e-02 1.068 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 8.543398e-02 1.068 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 8.739086e-02 1.059 0 0
Fanconi Anemia Pathway R-HSA-6783310 8.739086e-02 1.059 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 8.739086e-02 1.059 0 0
DAG and IP3 signaling R-HSA-1489509 8.739086e-02 1.059 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.897802e-02 1.051 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 9.273987e-02 1.033 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 9.553325e-02 1.020 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 9.553325e-02 1.020 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.638232e-02 1.016 0 0
Lipophagy R-HSA-9613354 9.886485e-02 1.005 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 9.886485e-02 1.005 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 9.886485e-02 1.005 0 0
ALK mutants bind TKIs R-HSA-9700645 9.886485e-02 1.005 0 0
Calcineurin activates NFAT R-HSA-2025928 9.886485e-02 1.005 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 9.886485e-02 1.005 0 0
ARMS-mediated activation R-HSA-170984 9.886485e-02 1.005 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 9.886485e-02 1.005 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 9.886485e-02 1.005 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 9.958921e-02 1.002 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 9.958921e-02 1.002 0 0
Signal transduction by L1 R-HSA-445144 9.958921e-02 1.002 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.023087e-01 0.990 0 0
Signalling to RAS R-HSA-167044 1.086147e-01 0.964 0 0
Signal amplification R-HSA-392518 1.092982e-01 0.961 0 0
Calnexin/calreticulin cycle R-HSA-901042 1.092982e-01 0.961 0 0
Signaling by NOTCH2 R-HSA-1980145 1.092982e-01 0.961 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.093851e-01 0.961 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 1.097605e-01 0.960 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.097605e-01 0.960 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 1.128364e-01 0.948 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 1.128364e-01 0.948 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 1.128364e-01 0.948 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.128364e-01 0.948 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.167923e-01 0.933 0 0
FOXO-mediated transcription R-HSA-9614085 1.167923e-01 0.933 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.169078e-01 0.932 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 1.181307e-01 0.928 0 0
Signaling by NTRKs R-HSA-166520 1.207619e-01 0.918 0 0
Circadian clock R-HSA-9909396 1.230278e-01 0.910 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.237462e-01 0.907 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 1.237462e-01 0.907 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.237462e-01 0.907 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 1.237462e-01 0.907 0 0
ARL13B-mediated ciliary trafficking of INPP5E R-HSA-5624958 1.237462e-01 0.907 0 0
NTRK3 as a dependence receptor R-HSA-9603505 1.237462e-01 0.907 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 1.238936e-01 0.907 0 0
GPVI-mediated activation cascade R-HSA-114604 1.238936e-01 0.907 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.250173e-01 0.903 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.250173e-01 0.903 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.255570e-01 0.901 0 0
vRNP Assembly R-HSA-192905 1.272774e-01 0.895 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 1.272774e-01 0.895 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.272774e-01 0.895 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 1.304548e-01 0.885 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.314857e-01 0.881 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.330835e-01 0.876 0 0
Protein localization R-HSA-9609507 1.391155e-01 0.857 0 0
Opioid Signalling R-HSA-111885 1.393265e-01 0.856 0 0
Toll-like Receptor Cascades R-HSA-168898 1.414371e-01 0.849 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.421215e-01 0.847 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.421215e-01 0.847 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 1.421215e-01 0.847 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.421215e-01 0.847 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.448595e-01 0.839 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.449196e-01 0.839 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.472222e-01 0.832 0 0
Pentose phosphate pathway R-HSA-71336 1.472222e-01 0.832 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 1.472222e-01 0.832 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.475732e-01 0.831 0 0
Signaling by NOTCH3 R-HSA-9012852 1.479009e-01 0.830 0 0
Ca2+ pathway R-HSA-4086398 1.507877e-01 0.822 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 1.507877e-01 0.822 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.547461e-01 0.810 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.552033e-01 0.809 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.553515e-01 0.809 0 0
Glycogen metabolism R-HSA-8982491 1.553515e-01 0.809 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.560974e-01 0.807 0 0
Disorders of Nervous System Development R-HSA-9697154 1.573073e-01 0.803 0 0
Pervasive developmental disorders R-HSA-9005895 1.573073e-01 0.803 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.573073e-01 0.803 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 1.573073e-01 0.803 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 1.579396e-01 0.802 0 0
G protein gated Potassium channels R-HSA-1296059 1.579396e-01 0.802 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 1.579396e-01 0.802 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.579396e-01 0.802 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.579396e-01 0.802 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 1.579396e-01 0.802 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 1.579396e-01 0.802 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.579396e-01 0.802 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 1.614978e-01 0.792 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 1.614978e-01 0.792 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 1.614978e-01 0.792 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 1.614978e-01 0.792 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 1.614978e-01 0.792 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 1.614978e-01 0.792 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 1.629619e-01 0.788 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.636443e-01 0.786 0 0
MET activates PTK2 signaling R-HSA-8874081 1.685217e-01 0.773 0 0
Translation of Structural Proteins R-HSA-9683701 1.720927e-01 0.764 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.727781e-01 0.763 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.727781e-01 0.763 0 0
Formation of axial mesoderm R-HSA-9796292 1.727781e-01 0.763 0 0
Frs2-mediated activation R-HSA-170968 1.727781e-01 0.763 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 1.727781e-01 0.763 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 1.727781e-01 0.763 0 0
Peroxisomal protein import R-HSA-9033241 1.760355e-01 0.754 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.785989e-01 0.748 0 0
Mitochondrial protein degradation R-HSA-9837999 1.785989e-01 0.748 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.793022e-01 0.746 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.793022e-01 0.746 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 1.793022e-01 0.746 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.793022e-01 0.746 0 0
Parasitic Infection Pathways R-HSA-9824443 1.812208e-01 0.742 0 0
Leishmania infection R-HSA-9658195 1.812208e-01 0.742 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.819750e-01 0.740 0 0
Neddylation R-HSA-8951664 1.824820e-01 0.739 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.833680e-01 0.737 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.833680e-01 0.737 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.833680e-01 0.737 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.833680e-01 0.737 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.833680e-01 0.737 0 0
CRMPs in Sema3A signaling R-HSA-399956 1.884811e-01 0.725 0 0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA R-HSA-77310 1.884811e-01 0.725 0 0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA R-HSA-77348 1.884811e-01 0.725 0 0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA R-HSA-77350 1.884811e-01 0.725 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.884811e-01 0.725 0 0
Signal regulatory protein family interactions R-HSA-391160 1.884811e-01 0.725 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 1.902640e-01 0.721 0 0
HIV elongation arrest and recovery R-HSA-167287 1.902640e-01 0.721 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.902640e-01 0.721 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.908108e-01 0.719 0 0
PLC beta mediated events R-HSA-112043 1.908108e-01 0.719 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.940112e-01 0.712 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 1.976252e-01 0.704 0 0
Classical Kir channels R-HSA-1296053 1.976252e-01 0.704 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.976252e-01 0.704 0 0
MET interacts with TNS proteins R-HSA-8875513 1.976252e-01 0.704 0 0
RMTs methylate histone arginines R-HSA-3214858 1.982907e-01 0.703 0 0
NCAM signaling for neurite out-growth R-HSA-375165 1.983589e-01 0.703 0 0
tRNA processing in the nucleus R-HSA-6784531 1.983589e-01 0.703 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 2.013903e-01 0.696 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 2.013903e-01 0.696 0 0
G beta:gamma signalling through BTK R-HSA-8964315 2.043677e-01 0.690 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 2.043677e-01 0.690 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 2.043677e-01 0.690 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.043677e-01 0.690 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 2.060077e-01 0.686 0 0
Extracellular matrix organization R-HSA-1474244 2.118469e-01 0.674 0 0
Interferon alpha/beta signaling R-HSA-909733 2.125415e-01 0.673 0 0
DAP12 signaling R-HSA-2424491 2.126646e-01 0.672 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 2.126646e-01 0.672 0 0
Activation of the pre-replicative complex R-HSA-68962 2.126646e-01 0.672 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.126646e-01 0.672 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 2.126646e-01 0.672 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 2.203931e-01 0.657 0 0
Prolonged ERK activation events R-HSA-169893 2.203931e-01 0.657 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 2.203931e-01 0.657 0 0
Mitotic Spindle Checkpoint R-HSA-69618 2.209685e-01 0.656 0 0
HCN channels R-HSA-1296061 2.321982e-01 0.634 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 2.321982e-01 0.634 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 2.321982e-01 0.634 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 2.321982e-01 0.634 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.321982e-01 0.634 0 0
Regulation of gap junction activity R-HSA-191650 2.321982e-01 0.634 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.321982e-01 0.634 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.321982e-01 0.634 0 0
NADE modulates death signalling R-HSA-205025 2.321982e-01 0.634 0 0
GPER1 signaling R-HSA-9634597 2.349042e-01 0.629 0 0
Diseases of mitotic cell cycle R-HSA-9675126 2.355927e-01 0.628 0 0
Inwardly rectifying K+ channels R-HSA-1296065 2.355927e-01 0.628 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 2.365160e-01 0.626 0 0
Disorders of Developmental Biology R-HSA-9675151 2.365160e-01 0.626 0 0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA R-HSA-77346 2.365160e-01 0.626 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 2.365160e-01 0.626 0 0
Response to metal ions R-HSA-5660526 2.365160e-01 0.626 0 0
G-protein mediated events R-HSA-112040 2.375093e-01 0.624 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 2.455863e-01 0.610 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 2.466377e-01 0.608 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 2.472153e-01 0.607 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 2.472153e-01 0.607 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 2.477283e-01 0.606 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 2.526982e-01 0.597 0 0
Effects of PIP2 hydrolysis R-HSA-114508 2.589235e-01 0.587 0 0
NTRK2 activates RAC1 R-HSA-9032759 2.652834e-01 0.576 0 0
G2 Phase R-HSA-68911 2.652834e-01 0.576 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 2.652834e-01 0.576 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.652834e-01 0.576 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.652834e-01 0.576 0 0
Suppression of autophagy R-HSA-9636569 2.652834e-01 0.576 0 0
Muscarinic acetylcholine receptors R-HSA-390648 2.652834e-01 0.576 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.652834e-01 0.576 0 0
Reelin signalling pathway R-HSA-8866376 2.652834e-01 0.576 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 2.689047e-01 0.570 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 2.689047e-01 0.570 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.689047e-01 0.570 0 0
Presynaptic function of Kainate receptors R-HSA-500657 2.689047e-01 0.570 0 0
Apoptotic factor-mediated response R-HSA-111471 2.689047e-01 0.570 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.689047e-01 0.570 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 2.707028e-01 0.568 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.729619e-01 0.564 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 2.729619e-01 0.564 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 2.785509e-01 0.555 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.826420e-01 0.549 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 2.851036e-01 0.545 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 2.851036e-01 0.545 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.851036e-01 0.545 0 0
The NLRP3 inflammasome R-HSA-844456 2.851036e-01 0.545 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 2.851036e-01 0.545 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 2.851036e-01 0.545 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.851036e-01 0.545 0 0
Disorders of transmembrane transporters R-HSA-5619115 2.918837e-01 0.535 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 2.944189e-01 0.531 0 0
RNA Polymerase III Transcription R-HSA-74158 2.944189e-01 0.531 0 0
RET signaling R-HSA-8853659 2.944189e-01 0.531 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 2.952498e-01 0.530 0 0
Plus-strand DNA synthesis R-HSA-164525 2.969449e-01 0.527 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.969449e-01 0.527 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.969449e-01 0.527 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.969449e-01 0.527 0 0
Pentose phosphate pathway disease R-HSA-6791465 2.969449e-01 0.527 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.969449e-01 0.527 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 2.969449e-01 0.527 0 0
Phosphorylation of Emi1 R-HSA-176417 2.969449e-01 0.527 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.969449e-01 0.527 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.969449e-01 0.527 0 0
TRAIL signaling R-HSA-75158 2.969449e-01 0.527 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.969449e-01 0.527 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.972477e-01 0.527 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 3.012653e-01 0.521 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 3.012653e-01 0.521 0 0
Protein hydroxylation R-HSA-9629569 3.012653e-01 0.521 0 0
Creatine metabolism R-HSA-71288 3.012653e-01 0.521 0 0
Ion homeostasis R-HSA-5578775 3.119574e-01 0.506 0 0
Signaling by NOTCH1 R-HSA-1980143 3.123268e-01 0.505 0 0
G-protein activation R-HSA-202040 3.173632e-01 0.498 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 3.173632e-01 0.498 0 0
ERK/MAPK targets R-HSA-198753 3.173632e-01 0.498 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.173632e-01 0.498 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 3.182570e-01 0.497 0 0
MET promotes cell motility R-HSA-8875878 3.182570e-01 0.497 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 3.182570e-01 0.497 0 0
Translation of Structural Proteins R-HSA-9694635 3.208610e-01 0.494 0 0
Potential therapeutics for SARS R-HSA-9679191 3.234906e-01 0.490 0 0
Erythropoietin activates STAT5 R-HSA-9027283 3.272438e-01 0.485 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.272438e-01 0.485 0 0
Uncoating of the HIV Virion R-HSA-162585 3.272438e-01 0.485 0 0
Metabolism of ingested MeSeO2H into MeSeH R-HSA-5263617 3.272438e-01 0.485 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 3.272438e-01 0.485 0 0
CREB phosphorylation R-HSA-199920 3.272438e-01 0.485 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.272438e-01 0.485 0 0
VLDL assembly R-HSA-8866423 3.272438e-01 0.485 0 0
G alpha (12/13) signalling events R-HSA-416482 3.294217e-01 0.482 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.301908e-01 0.481 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.301908e-01 0.481 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 3.301908e-01 0.481 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 3.333727e-01 0.477 0 0
Mitochondrial calcium ion transport R-HSA-8949215 3.333727e-01 0.477 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.333727e-01 0.477 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 3.333727e-01 0.477 0 0
Ribavirin ADME R-HSA-9755088 3.333727e-01 0.477 0 0
Sensory processing of sound R-HSA-9659379 3.380044e-01 0.471 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 3.415320e-01 0.467 0 0
snRNP Assembly R-HSA-191859 3.415320e-01 0.467 0 0
Metabolism of non-coding RNA R-HSA-194441 3.415320e-01 0.467 0 0
HIV Transcription Elongation R-HSA-167169 3.421188e-01 0.466 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.421188e-01 0.466 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.421188e-01 0.466 0 0
Post-translational protein phosphorylation R-HSA-8957275 3.487281e-01 0.458 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 3.492716e-01 0.457 0 0
Fructose metabolism R-HSA-5652084 3.492716e-01 0.457 0 0
RAB geranylgeranylation R-HSA-8873719 3.514154e-01 0.454 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.514154e-01 0.454 0 0
Metabolism of polyamines R-HSA-351202 3.514154e-01 0.454 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 3.540298e-01 0.451 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.540298e-01 0.451 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 3.547500e-01 0.450 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 3.562388e-01 0.448 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 3.562388e-01 0.448 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.562388e-01 0.448 0 0
DAG1 core M1 glycosylations R-HSA-8932506 3.562388e-01 0.448 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.562388e-01 0.448 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.562388e-01 0.448 0 0
PTK6 Expression R-HSA-8849473 3.562388e-01 0.448 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 3.562388e-01 0.448 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.562388e-01 0.448 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.562388e-01 0.448 0 0
LDL remodeling R-HSA-8964041 3.562388e-01 0.448 0 0
Netrin mediated repulsion signals R-HSA-418886 3.562388e-01 0.448 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.562388e-01 0.448 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 3.562388e-01 0.448 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 3.562388e-01 0.448 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.562388e-01 0.448 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.562388e-01 0.448 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 3.650398e-01 0.438 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.650398e-01 0.438 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.650398e-01 0.438 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.650398e-01 0.438 0 0
Mitochondrial protein import R-HSA-1268020 3.711802e-01 0.430 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 3.777597e-01 0.423 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 3.777597e-01 0.423 0 0
Activation of GABAB receptors R-HSA-991365 3.777597e-01 0.423 0 0
GABA B receptor activation R-HSA-977444 3.777597e-01 0.423 0 0
Thromboxane signalling through TP receptor R-HSA-428930 3.806589e-01 0.419 0 0
Mitochondrial RNA degradation R-HSA-9836573 3.806589e-01 0.419 0 0
Complex III assembly R-HSA-9865881 3.806589e-01 0.419 0 0
Reverse Transcription of HIV RNA R-HSA-162589 3.839858e-01 0.416 0 0
Minus-strand DNA synthesis R-HSA-164516 3.839858e-01 0.416 0 0
DAG1 core M2 glycosylations R-HSA-8932504 3.839858e-01 0.416 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.839858e-01 0.416 0 0
Regulation by c-FLIP R-HSA-3371378 3.839858e-01 0.416 0 0
Fructose biosynthesis R-HSA-5652227 3.839858e-01 0.416 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.839858e-01 0.416 0 0
Dimerization of procaspase-8 R-HSA-69416 3.839858e-01 0.416 0 0
Adrenoceptors R-HSA-390696 3.839858e-01 0.416 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 3.839858e-01 0.416 0 0
Interleukin-23 signaling R-HSA-9020933 3.839858e-01 0.416 0 0
TBC/RABGAPs R-HSA-8854214 3.895589e-01 0.409 0 0
Ion transport by P-type ATPases R-HSA-936837 3.909012e-01 0.408 0 0
Asparagine N-linked glycosylation R-HSA-446203 3.963938e-01 0.402 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 3.983241e-01 0.400 0 0
DAP12 interactions R-HSA-2172127 4.013021e-01 0.397 0 0
CASP8 activity is inhibited R-HSA-5218900 4.105384e-01 0.387 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 4.105384e-01 0.387 0 0
Unwinding of DNA R-HSA-176974 4.105384e-01 0.387 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 4.105384e-01 0.387 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 4.105384e-01 0.387 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 4.105384e-01 0.387 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 4.105384e-01 0.387 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 4.105384e-01 0.387 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 4.105384e-01 0.387 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.113863e-01 0.386 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.113863e-01 0.386 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 4.113863e-01 0.386 0 0
Urea cycle R-HSA-70635 4.113863e-01 0.386 0 0
Diseases of DNA repair R-HSA-9675135 4.245863e-01 0.372 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 4.245863e-01 0.372 0 0
Cristae formation R-HSA-8949613 4.264667e-01 0.370 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 4.264667e-01 0.370 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 4.264667e-01 0.370 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 4.264667e-01 0.370 0 0
Ion channel transport R-HSA-983712 4.335393e-01 0.363 0 0
Stimuli-sensing channels R-HSA-2672351 4.338370e-01 0.363 0 0
Binding and entry of HIV virion R-HSA-173107 4.359481e-01 0.361 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.359481e-01 0.361 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 4.359481e-01 0.361 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 4.359481e-01 0.361 0 0
MAPK3 (ERK1) activation R-HSA-110056 4.359481e-01 0.361 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 4.359481e-01 0.361 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 4.359481e-01 0.361 0 0
Receptor Mediated Mitophagy R-HSA-8934903 4.359481e-01 0.361 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 4.397121e-01 0.357 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 4.413420e-01 0.355 0 0
Inflammasomes R-HSA-622312 4.413420e-01 0.355 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 4.413420e-01 0.355 0 0
Pyroptosis R-HSA-5620971 4.413420e-01 0.355 0 0
Gastrulation R-HSA-9758941 4.539818e-01 0.343 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 4.560020e-01 0.341 0 0
Glucagon-type ligand receptors R-HSA-420092 4.560020e-01 0.341 0 0
IRE1alpha activates chaperones R-HSA-381070 4.580637e-01 0.339 0 0
ECM proteoglycans R-HSA-3000178 4.589312e-01 0.338 0 0
DAG1 core M3 glycosylations R-HSA-8932505 4.602639e-01 0.337 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.602639e-01 0.337 0 0
vRNA Synthesis R-HSA-192814 4.602639e-01 0.337 0 0
Chylomicron assembly R-HSA-8963888 4.602639e-01 0.337 0 0
Bicarbonate transporters R-HSA-425381 4.602639e-01 0.337 0 0
Suppression of apoptosis R-HSA-9635465 4.602639e-01 0.337 0 0
Interleukin-2 signaling R-HSA-9020558 4.602639e-01 0.337 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.602639e-01 0.337 0 0
Inositol phosphate metabolism R-HSA-1483249 4.644503e-01 0.333 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 4.664768e-01 0.331 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 4.684567e-01 0.329 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 4.704376e-01 0.327 0 0
The phototransduction cascade R-HSA-2514856 4.812721e-01 0.318 0 0
Signaling by GSK3beta mutants R-HSA-5339716 4.835329e-01 0.316 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.835329e-01 0.316 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.835329e-01 0.316 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.835329e-01 0.316 0 0
Plasmalogen biosynthesis R-HSA-75896 4.835329e-01 0.316 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 4.835329e-01 0.316 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 4.835329e-01 0.316 0 0
Integration of provirus R-HSA-162592 4.835329e-01 0.316 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 4.846410e-01 0.315 0 0
Molecules associated with elastic fibres R-HSA-2129379 4.846410e-01 0.315 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 4.871261e-01 0.312 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 4.873185e-01 0.312 0 0
mRNA 3'-end processing R-HSA-72187 4.922965e-01 0.308 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 4.922965e-01 0.308 0 0
Iron uptake and transport R-HSA-917937 4.966471e-01 0.304 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 5.032039e-01 0.298 0 0
Nucleotide biosynthesis R-HSA-8956320 5.032039e-01 0.298 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 5.058001e-01 0.296 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 5.058001e-01 0.296 0 0
Scavenging by Class F Receptors R-HSA-3000484 5.058001e-01 0.296 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 5.058001e-01 0.296 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 5.058001e-01 0.296 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 5.058001e-01 0.296 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 5.058001e-01 0.296 0 0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA R-HSA-77305 5.058001e-01 0.296 0 0
Beta oxidation of myristoyl-CoA to lauroyl-CoA R-HSA-77285 5.058001e-01 0.296 0 0
GRB2 events in EGFR signaling R-HSA-179812 5.058001e-01 0.296 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 5.058001e-01 0.296 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 5.058001e-01 0.296 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 5.058001e-01 0.296 0 0
OAS antiviral response R-HSA-8983711 5.058001e-01 0.296 0 0
Potassium Channels R-HSA-1296071 5.078816e-01 0.294 0 0
Integration of energy metabolism R-HSA-163685 5.108700e-01 0.292 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 5.123248e-01 0.290 0 0
G-protein beta:gamma signalling R-HSA-397795 5.123248e-01 0.290 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 5.123248e-01 0.290 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 5.123248e-01 0.290 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 5.123248e-01 0.290 0 0
Rab regulation of trafficking R-HSA-9007101 5.168643e-01 0.287 0 0
Integrin cell surface interactions R-HSA-216083 5.241813e-01 0.281 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 5.257946e-01 0.279 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 5.257946e-01 0.279 0 0
Processing of SMDT1 R-HSA-8949664 5.271086e-01 0.278 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 5.271086e-01 0.278 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 5.271086e-01 0.278 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.271086e-01 0.278 0 0
eNOS activation R-HSA-203615 5.390107e-01 0.268 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 5.390107e-01 0.268 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 5.390107e-01 0.268 0 0
Retrograde neurotrophin signalling R-HSA-177504 5.474995e-01 0.262 0 0
Prolactin receptor signaling R-HSA-1170546 5.474995e-01 0.262 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 5.474995e-01 0.262 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 5.474995e-01 0.262 0 0
Malate-aspartate shuttle R-HSA-9856872 5.474995e-01 0.262 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 5.474995e-01 0.262 0 0
Acyl chain remodeling of CL R-HSA-1482798 5.474995e-01 0.262 0 0
Zinc transporters R-HSA-435354 5.474995e-01 0.262 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.474995e-01 0.262 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 5.519700e-01 0.258 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 5.558345e-01 0.255 0 0
RUNX2 regulates bone development R-HSA-8941326 5.646701e-01 0.248 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 5.646701e-01 0.248 0 0
Erythropoietin activates RAS R-HSA-9027284 5.670124e-01 0.246 0 0
SHC1 events in EGFR signaling R-HSA-180336 5.670124e-01 0.246 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.670124e-01 0.246 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 5.670124e-01 0.246 0 0
Beta oxidation of butanoyl-CoA to acetyl-CoA R-HSA-77352 5.670124e-01 0.246 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.670124e-01 0.246 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 5.670124e-01 0.246 0 0
Other semaphorin interactions R-HSA-416700 5.670124e-01 0.246 0 0
tRNA Aminoacylation R-HSA-379724 5.759312e-01 0.240 0 0
GABA receptor activation R-HSA-977443 5.759312e-01 0.240 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.856849e-01 0.232 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.856849e-01 0.232 0 0
Phosphorylation of the APC/C R-HSA-176412 5.856849e-01 0.232 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.856849e-01 0.232 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.856849e-01 0.232 0 0
Atorvastatin ADME R-HSA-9754706 5.856849e-01 0.232 0 0
Fructose catabolism R-HSA-70350 5.856849e-01 0.232 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.856849e-01 0.232 0 0
Attachment and Entry R-HSA-9678110 5.856849e-01 0.232 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.857636e-01 0.232 0 0
Elastic fibre formation R-HSA-1566948 5.892862e-01 0.230 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 5.892862e-01 0.230 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 5.892862e-01 0.230 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 6.020480e-01 0.220 0 0
XBP1(S) activates chaperone genes R-HSA-381038 6.020480e-01 0.220 0 0
Fibronectin matrix formation R-HSA-1566977 6.035533e-01 0.219 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 6.035533e-01 0.219 0 0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids R-HSA-77288 6.035533e-01 0.219 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 6.035533e-01 0.219 0 0
Galactose catabolism R-HSA-70370 6.035533e-01 0.219 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 6.035533e-01 0.219 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 6.128524e-01 0.213 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 6.128524e-01 0.213 0 0
Generation of second messenger molecules R-HSA-202433 6.128524e-01 0.213 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 6.128524e-01 0.213 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 6.206521e-01 0.207 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 6.206521e-01 0.207 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 6.206521e-01 0.207 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 6.206521e-01 0.207 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 6.206521e-01 0.207 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 6.206521e-01 0.207 0 0
PKMTs methylate histone lysines R-HSA-3214841 6.242420e-01 0.205 0 0
Cardiac conduction R-HSA-5576891 6.279039e-01 0.202 0 0
Mismatch Repair R-HSA-5358508 6.370145e-01 0.196 0 0
Polo-like kinase mediated events R-HSA-156711 6.370145e-01 0.196 0 0
Platelet sensitization by LDL R-HSA-432142 6.370145e-01 0.196 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.370145e-01 0.196 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 6.370145e-01 0.196 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.370145e-01 0.196 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 6.462390e-01 0.190 0 0
Transcription of the HIV genome R-HSA-167172 6.503969e-01 0.187 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 6.503969e-01 0.187 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 6.526720e-01 0.185 0 0
Germ layer formation at gastrulation R-HSA-9754189 6.526720e-01 0.185 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.526720e-01 0.185 0 0
Specification of the neural plate border R-HSA-9834899 6.526720e-01 0.185 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.526720e-01 0.185 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 6.526720e-01 0.185 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.526720e-01 0.185 0 0
Interferon gamma signaling R-HSA-877300 6.619866e-01 0.179 0 0
Amine ligand-binding receptors R-HSA-375280 6.672037e-01 0.176 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 6.676551e-01 0.175 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.676551e-01 0.175 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 6.676551e-01 0.175 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.676551e-01 0.175 0 0
Formation of definitive endoderm R-HSA-9823730 6.676551e-01 0.175 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.676551e-01 0.175 0 0
Pregnenolone biosynthesis R-HSA-196108 6.676551e-01 0.175 0 0
Collagen formation R-HSA-1474290 6.717008e-01 0.173 0 0
mitochondrial fatty acid beta-oxidation of saturated fatty acids R-HSA-77286 6.773042e-01 0.169 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 6.773042e-01 0.169 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 6.773042e-01 0.169 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 6.819927e-01 0.166 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 6.819927e-01 0.166 0 0
Early Phase of HIV Life Cycle R-HSA-162594 6.819927e-01 0.166 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 6.819927e-01 0.166 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.819927e-01 0.166 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.871535e-01 0.163 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.871535e-01 0.163 0 0
Cell surface interactions at the vascular wall R-HSA-202733 6.946262e-01 0.158 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 6.957125e-01 0.158 0 0
Serine metabolism R-HSA-977347 6.957125e-01 0.158 0 0
Attachment and Entry R-HSA-9694614 6.957125e-01 0.158 0 0
Signaling by PDGFR in disease R-HSA-9671555 6.957125e-01 0.158 0 0
G alpha (q) signalling events R-HSA-416476 7.054631e-01 0.152 0 0
Regulation of insulin secretion R-HSA-422356 7.065709e-01 0.151 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 7.088413e-01 0.149 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 7.088413e-01 0.149 0 0
LDL clearance R-HSA-8964038 7.088413e-01 0.149 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 7.088413e-01 0.149 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 7.088413e-01 0.149 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 7.195438e-01 0.143 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 7.214044e-01 0.142 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 7.214044e-01 0.142 0 0
Formation of the ureteric bud R-HSA-9830674 7.214044e-01 0.142 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 7.214044e-01 0.142 0 0
Mitochondrial mRNA modification R-HSA-9937008 7.214044e-01 0.142 0 0
Biosynthesis of maresins R-HSA-9018682 7.214044e-01 0.142 0 0
Growth hormone receptor signaling R-HSA-982772 7.214044e-01 0.142 0 0
Azathioprine ADME R-HSA-9748787 7.240998e-01 0.140 0 0
tRNA processing R-HSA-72306 7.258348e-01 0.139 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 7.334261e-01 0.135 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 7.334261e-01 0.135 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.334261e-01 0.135 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 7.367877e-01 0.133 0 0
Leishmania parasite growth and survival R-HSA-9664433 7.404307e-01 0.131 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 7.404307e-01 0.131 0 0
Laminin interactions R-HSA-3000157 7.449298e-01 0.128 0 0
Tight junction interactions R-HSA-420029 7.449298e-01 0.128 0 0
HDMs demethylate histones R-HSA-3214842 7.449298e-01 0.128 0 0
Interleukin-7 signaling R-HSA-1266695 7.449298e-01 0.128 0 0
Formation of the nephric duct R-HSA-9830364 7.449298e-01 0.128 0 0
Amino acids regulate mTORC1 R-HSA-9639288 7.493319e-01 0.125 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 7.559377e-01 0.122 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 7.559377e-01 0.122 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 7.559377e-01 0.122 0 0
TRP channels R-HSA-3295583 7.559377e-01 0.122 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.559377e-01 0.122 0 0
Platelet homeostasis R-HSA-418346 7.623883e-01 0.118 0 0
Signaling by BMP R-HSA-201451 7.664712e-01 0.116 0 0
Insulin processing R-HSA-264876 7.664712e-01 0.116 0 0
NRAGE signals death through JNK R-HSA-193648 7.725543e-01 0.112 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 7.765507e-01 0.110 0 0
Formation of the Early Elongation Complex R-HSA-113418 7.765507e-01 0.110 0 0
Telomere Extension By Telomerase R-HSA-171319 7.765507e-01 0.110 0 0
Prednisone ADME R-HSA-9757110 7.765507e-01 0.110 0 0
Dectin-2 family R-HSA-5621480 7.798674e-01 0.108 0 0
Signaling by Erythropoietin R-HSA-9006335 7.861957e-01 0.104 0 0
mRNA Capping R-HSA-72086 7.861957e-01 0.104 0 0
Thyroxine biosynthesis R-HSA-209968 7.861957e-01 0.104 0 0
Platelet calcium homeostasis R-HSA-418360 7.861957e-01 0.104 0 0
DARPP-32 events R-HSA-180024 7.861957e-01 0.104 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 7.938773e-01 0.100 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.954250e-01 0.099 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.954250e-01 0.099 0 0
Downstream signal transduction R-HSA-186763 8.042564e-01 0.095 0 0
Aquaporin-mediated transport R-HSA-445717 8.070935e-01 0.093 0 0
DAG1 glycosylations R-HSA-8931838 8.127071e-01 0.090 0 0
Signaling by WNT in cancer R-HSA-4791275 8.127071e-01 0.090 0 0
DNA strand elongation R-HSA-69190 8.127071e-01 0.090 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 8.134146e-01 0.090 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 8.195501e-01 0.086 0 0
Nuclear RNA decay R-HSA-9930044 8.207934e-01 0.086 0 0
Cardiogenesis R-HSA-9733709 8.207934e-01 0.086 0 0
Recycling of bile acids and salts R-HSA-159418 8.207934e-01 0.086 0 0
CD22 mediated BCR regulation R-HSA-5690714 8.255041e-01 0.083 0 0
Xenobiotics R-HSA-211981 8.255041e-01 0.083 0 0
Mitochondrial biogenesis R-HSA-1592230 8.279719e-01 0.082 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 8.285311e-01 0.082 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.285311e-01 0.082 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.312160e-01 0.080 0 0
FCGR activation R-HSA-2029481 8.312160e-01 0.080 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 8.359352e-01 0.078 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 8.359352e-01 0.078 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 8.359352e-01 0.078 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 8.368848e-01 0.077 0 0
Kidney development R-HSA-9830369 8.423198e-01 0.075 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 8.430199e-01 0.074 0 0
Triglyceride catabolism R-HSA-163560 8.497992e-01 0.071 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.497992e-01 0.071 0 0
Voltage gated Potassium channels R-HSA-1296072 8.562860e-01 0.067 0 0
Collagen chain trimerization R-HSA-8948216 8.562860e-01 0.067 0 0
Formation of the cornified envelope R-HSA-6809371 8.565860e-01 0.067 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 8.576528e-01 0.067 0 0
Bacterial Infection Pathways R-HSA-9824439 8.654766e-01 0.063 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.681910e-01 0.061 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.684325e-01 0.061 0 0
Signaling by ALK R-HSA-201556 8.684325e-01 0.061 0 0
Aspirin ADME R-HSA-9749641 8.716120e-01 0.060 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 8.741157e-01 0.058 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.741157e-01 0.058 0 0
Diseases of Immune System R-HSA-5260271 8.741157e-01 0.058 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.741157e-01 0.058 0 0
Interleukin-2 family signaling R-HSA-451927 8.741157e-01 0.058 0 0
Metabolism of nucleotides R-HSA-15869 8.754800e-01 0.058 0 0
PPARA activates gene expression R-HSA-1989781 8.775857e-01 0.057 0 0
Aflatoxin activation and detoxification R-HSA-5423646 8.795537e-01 0.056 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 8.795537e-01 0.056 0 0
Maturation of spike protein R-HSA-9694548 8.795537e-01 0.056 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 8.802067e-01 0.055 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.835277e-01 0.054 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.847571e-01 0.053 0 0
HIV Transcription Initiation R-HSA-167161 8.847571e-01 0.053 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.847571e-01 0.053 0 0
Scavenging by Class A Receptors R-HSA-3000480 8.847571e-01 0.053 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.847571e-01 0.053 0 0
Adipogenesis R-HSA-9843745 8.873372e-01 0.052 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 8.882673e-01 0.051 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.897360e-01 0.051 0 0
Interleukin-10 signaling R-HSA-6783783 8.921063e-01 0.050 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.945001e-01 0.048 0 0
G alpha (i) signalling events R-HSA-418594 8.986752e-01 0.046 0 0
Methylation R-HSA-156581 8.990587e-01 0.046 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 8.990587e-01 0.046 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 9.034205e-01 0.044 0 0
Signaling by TGFBR3 R-HSA-9839373 9.075941e-01 0.042 0 0
SLC transporter disorders R-HSA-5619102 9.096629e-01 0.041 0 0
Metal ion SLC transporters R-HSA-425410 9.154088e-01 0.038 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.154088e-01 0.038 0 0
NGF-stimulated transcription R-HSA-9031628 9.154088e-01 0.038 0 0
G alpha (s) signalling events R-HSA-418555 9.206937e-01 0.036 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.215295e-01 0.035 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.225634e-01 0.035 0 0
Neurexins and neuroligins R-HSA-6794361 9.291137e-01 0.032 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.320211e-01 0.031 0 0
Glucuronidation R-HSA-156588 9.351106e-01 0.029 0 0
Paracetamol ADME R-HSA-9753281 9.379163e-01 0.028 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.406008e-01 0.027 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.453023e-01 0.024 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.474119e-01 0.023 0 0
Extension of Telomeres R-HSA-180786 9.479787e-01 0.023 0 0
Triglyceride metabolism R-HSA-8979227 9.479787e-01 0.023 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.491520e-01 0.023 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.491520e-01 0.023 0 0
Endogenous sterols R-HSA-211976 9.523814e-01 0.021 0 0
Collagen degradation R-HSA-1442490 9.523814e-01 0.021 0 0
Signaling by PDGF R-HSA-186797 9.544413e-01 0.020 0 0
Complex I biogenesis R-HSA-6799198 9.564121e-01 0.019 0 0
PI Metabolism R-HSA-1483255 9.592102e-01 0.018 0 0
Metabolism of steroid hormones R-HSA-196071 9.634799e-01 0.016 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.694031e-01 0.013 0 0
Metabolism of cofactors R-HSA-8978934 9.694031e-01 0.013 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.708045e-01 0.013 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.729110e-01 0.012 0 0
Signaling by FGFR in disease R-HSA-1226099 9.732068e-01 0.012 0 0
Visual phototransduction R-HSA-2187338 9.762481e-01 0.010 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.775552e-01 0.010 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.785260e-01 0.009 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.785260e-01 0.009 0 0
Peptide hormone metabolism R-HSA-2980736 9.791886e-01 0.009 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.803456e-01 0.009 0 0
Protein-protein interactions at synapses R-HSA-6794362 9.835359e-01 0.007 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.849315e-01 0.007 0 0
Neurotransmitter release cycle R-HSA-112310 9.873782e-01 0.006 0 0
GPCR downstream signalling R-HSA-388396 9.888378e-01 0.005 0 0
Keratinization R-HSA-6805567 9.896626e-01 0.005 0 0
Respiratory electron transport R-HSA-611105 9.921730e-01 0.003 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.922481e-01 0.003 0 0
Drug ADME R-HSA-9748784 9.930349e-01 0.003 0 0
Metabolism of steroids R-HSA-8957322 9.934711e-01 0.003 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.950016e-01 0.002 0 0
Antimicrobial peptides R-HSA-6803157 9.956447e-01 0.002 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.966628e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.969377e-01 0.001 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.974432e-01 0.001 0 0
Signaling by GPCR R-HSA-372790 9.978943e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.985648e-01 0.001 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.988223e-01 0.001 0 0
Peptide ligand-binding receptors R-HSA-375276 9.988491e-01 0.001 0 0
O-linked glycosylation R-HSA-5173105 9.989007e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.991704e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.991947e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.994604e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.998165e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.998720e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.998759e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.999050e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999415e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999469e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999634e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999848e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999984e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999990e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999993e-01 0.000 0 0
Biological oxidations R-HSA-211859 9.999995e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways