RSK3
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0A2R8Y4L2 | S95 | Sugiyama | HNRNPA1L3 HNRNPA1P48 | RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED |
| A4FU28 | S140 | Sugiyama | CTAGE9 | AAAEEARSLEATCEKLSRsNsELEDEILCLEKDLKEEKSKH |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A8K0Z3 | S105 | Sugiyama | WASHC1 FAM39E WASH1 | AIKVFSSAKYPAPGRLQEyGsIFTGAQDPGLQRRPRHRIQS |
| C4AMC7 | S105 | Sugiyama | WASH3P FAM39DP | AIKVFSSAKYPAPERLQEyGsIFTGAQDPGLQRRPRHRIQS |
| O00116 | S65 | Sugiyama | AGPS AAG5 | LLGRPREALSTNECKARRAAsAAtAAPtAtPAAQEsGtIPK |
| O00170 | S43 | Sugiyama | AIP XAP2 | GELPDFQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELI |
| O00232 | S335 | Sugiyama | PSMD12 | MRWSTLVEDYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLK |
| O00267 | S818 | Sugiyama | SUPT5H SPT5 SPT5H | RtPHyGsQtPLHDGsRtPAQsGAWDPNNPNtPsRAEEEYEY |
| O00418 | S366 | ELM|EPSD | EEF2K | AKtILRGtEEKCGsPQVRTLsGSRPPLLRPLsENSGDENMS |
| O00488 | S93 | Sugiyama | ZNF593 ZT86 | STNLKTHFRSKDHKKRLKQLsVEPysQEEAERAAGMGSYVP |
| O14579 | S99 | Sugiyama | COPE | PELQAVRMFADyLAHEsRRDsIVAELDREMsRSVDVTNTTF |
| O14617 | S658 | Sugiyama | AP3D1 PRO0039 | DERPRAVFHEEEQRRPKHRPsEADEEELARRREARKQEQAN |
| O14618 | S267 | Sugiyama | CCS | DGLTIWEERGRPIAGKGRKEsAQPPAHL_____________ |
| O14907 | S61 | Sugiyama | TAX1BP3 TIP1 | PSQNPFSEDKTDKGIYVtRVsEGGPAEIAGLQIGDKIMQVN |
| O14974 | S187 | Sugiyama | PPP1R12A MBS MYPT1 | EAARKEEERIMLRDARQWLNsGHINDVRHAKSGGTALHVAA |
| O14980 | S1055 | Sugiyama | XPO1 CRM1 | LEEREIALRQADEEKHKRQMsVPGIFNPHEIPEEMCD____ |
| O15067 | S215 | Sugiyama | PFAS KIAA0361 | LDSWDLDFYTKRFQELQRNPstVEAFDLAQsNsEHSRHWFF |
| O15143 | S328 | Sugiyama | ARPC1B ARC41 | KAssEGGtAAGAGLDsLHKNsVsQIsVLsGGKAKCSQFCTT |
| O15226 | S616 | Sugiyama | NKRF ITBA4 NRF | ERVNKIAKRDIEQIIRNYARsEsHtDLtFsRELTNDERKQI |
| O15226 | S618 | Sugiyama | NKRF ITBA4 NRF | VNKIAKRDIEQIIRNYARsEsHtDLtFsRELTNDERKQIHQ |
| O15234 | S10 | Sugiyama | CASC3 MLN51 | ___________MADRRRQRAsQDtEDEESGASGsDsGGsPL |
| O15372 | S290 | Sugiyama | EIF3H EIF3S3 | QQQQKHQYQQRRQQENMQRQsRGEPPLPEEDLsKLFKPPQP |
| O15460 | S531 | Sugiyama | P4HA2 UNQ290/PRO330 | KWVSNKWFHERGQEFLRPCGstEVD________________ |
| O43175 | S12 | Sugiyama | PHGDH PGDH3 | _________MAFANLRKVLIsDsLDPCCRKILQDGGLQVVE |
| O43379 | S49 | Sugiyama | WDR62 C19orf14 | RGQssPPPAPPICLRRRtRLstAsEETVQNRVsLEKVLGIT |
| O43379 | T50 | Sugiyama | WDR62 C19orf14 | GQssPPPAPPICLRRRtRLstAsEETVQNRVsLEKVLGITA |
| O43390 | S426 | Sugiyama | HNRNPR HNRPR | IVLAKPPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPI |
| O43390 | S428 | Sugiyama | HNRNPR HNRPR | LAKPPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRG |
| O43390 | T429 | Sugiyama | HNRNPR HNRPR | AKPPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGR |
| O43390 | Y431 | Sugiyama | HNRNPR HNRPR | PPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGR |
| O43488 | S40 | Sugiyama | AKR7A2 AFAR AFAR1 AKR7 | SPPPEARALAMSRPPPPRVAsVLGTMEMGRRMDAPAsAAAV |
| O43633 | S203 | Sugiyama | CHMP2A BC2 CHMP2 | PSTGGSLSVAAGGKKAEAAAsALADADADLEERLKNLRRD_ |
| O43707 | S423 | Sugiyama | ACTN4 | NEIRRLERLDHLAEKFRQKAsIHEAWtDGKEAMLKHRDyEt |
| O43823 | S323 | Sugiyama | AKAP8 AKAP95 | RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE |
| O43847 | S94 | Sugiyama | NRDC NRD1 | ENSRVARLGADEsEEEGRRGsLsNAGDPEIVKsPsDPKQYR |
| O43852 | S261 | Sugiyama | CALU | RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK |
| O43852 | S44 | Sugiyama | CALU | KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60293 | S42 | Sugiyama | ZFC3H1 CCDC131 KIAA0546 PSRC2 | LEDGEIsDDDNNSQIRSRsssSsSGGGLLPYPRRRPPHSAR |
| O60333 | S649 | Sugiyama | KIF1B KIAA0591 KIAA1448 | NHVFRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEK |
| O60333 | S654 | Sugiyama | KIF1B KIAA0591 KIAA1448 | FNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEKQGIDM |
| O60664 | T216 | Sugiyama | PLIN3 M6PRBP1 TIP47 | sEEWADNHLPLTDAELARIAtsLDGFDVAsVQQQRQEQSyF |
| O60716 | S859 | Sugiyama | CTNND1 KIAA0384 | LEKEGWKKsDFQVNLNNAsRsQssHsyDDstLPLIDRNQKs |
| O60739 | T46 | Sugiyama | EIF1B | GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK |
| O60814 | S37 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| O60841 | S107 | Sugiyama | EIF5B IF2 KIAA0741 | NEEEFtsKDKKKKGQKGKKQsFDDNDsEELEDKDsKSKKTA |
| O60841 | S182 | Sugiyama | EIF5B IF2 KIAA0741 | DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK |
| O60841 | S183 | Sugiyama | EIF5B IF2 KIAA0741 | GsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKN |
| O75030 | S516 | EPSD | MITF BHLHE32 | tDPLLssVsPGAsKTSSRRssMsMEETEHTC__________ |
| O75152 | S758 | Sugiyama | ZC3H11A KIAA0663 ZC3HDC11A | sPPEVsGPSSSQMSMKTRRLssAstGKPPLsVEDDFEKLIW |
| O75152 | S759 | Sugiyama | ZC3H11A KIAA0663 ZC3HDC11A | PPEVsGPSSSQMSMKTRRLssAstGKPPLsVEDDFEKLIWE |
| O75347 | S103 | Sugiyama | TBCA | ENEKDLEEAEEyKEARLVLDsVKLEA_______________ |
| O75369 | S1442 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | SKVKIAGPGLGsGVRARVLQsFtVDSSKAGLAPLEVRVLGP |
| O75534 | S584 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | YSLSKGKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRP |
| O75874 | S6 | Sugiyama | IDH1 PICD | _______________MSKKIsGGsVVEMQGDEMTRIIWELI |
| O75874 | S9 | Sugiyama | IDH1 PICD | ____________MSKKIsGGsVVEMQGDEMTRIIWELIKEK |
| O75937 | S81 | Sugiyama | DNAJC8 SPF31 HSPC315 HSPC331 | VLQIDPEVTDEEIKKRFRQLsILVHPDKNQDDADRAQKAFE |
| O76003 | S117 | Sugiyama | GLRX3 PICOT TXNL2 HUSSY-22 | IDRLDGAHAPELTKKVQRHAssGsFLPSANEHLKEDLNLRL |
| O94915 | S1957 | Sugiyama | FRYL AF4P12 KIAA0826 | ARsNsLRLsLIGDRRGDRRRsNtLDIMDGRINHsssLARtR |
| O95071 | S2369 | Sugiyama | UBR5 EDD EDD1 HYD KIAA0896 | SSGLRAGSRRDRDRDFRRQLsIDTRPFRPASEGNPsDDPEP |
| O95071 | S2384 | Sugiyama | UBR5 EDD EDD1 HYD KIAA0896 | FRRQLsIDTRPFRPASEGNPsDDPEPLPAHRQALGERLYPR |
| O95155 | S105 | Sugiyama | UBE4B HDNB1 KIAA0684 UFD2 | LsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsMsQVDVDsG |
| O95218 | S181 | Sugiyama | ZRANB2 ZIS ZNF265 | DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR |
| O95757 | S599 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND |
| O95816 | S31 | Sugiyama | BAG2 | NEGRFCRsssMADRsSRLLEsLDQLELRVEALREAATAVEQ |
| O95831 | S116 | Sugiyama | AIFM1 AIF PDCD8 | NERIsGLGLtPEQKQKKAALsAsEGEEVPQDKAPSHVPFLL |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S310 | Sugiyama | LDHA PIG19 | SVPCILGQNGISDLVKVTLtsEEEARLKKsADtLWGIQKEL |
| P00338 | S319 | Sugiyama | LDHA PIG19 | GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______ |
| P00491 | S176 | Sugiyama | PNP NP | GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA |
| P00491 | T177 | Sugiyama | PNP NP | DRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVAG |
| P00558 | S174 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | S393 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA |
| P00558 | S399 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__ |
| P00568 | T39 | Sugiyama | AK1 | SGKGTQCEKIVQKyGytHLstGDLLRSEVSSGSARGKKLsE |
| P01100 | S362 | ELM|EPSD | FOS G0S7 | VFTYPEADSFPSCAAAHRKGsSsNEPSSDSLSsPTLLAL__ |
| P02545 | S458 | Sugiyama | LMNA LMN1 | GRVAVEEVDEEGKFVRLRNKsNEDQsMGNWQIKRQNGDDPL |
| P02786 | S159 | Sugiyama | TFRC | DFTGtIKLLNENsyVPREAGsQKDENLALyVENQFREFKLS |
| P03372 | S118 | ELM|EPSD | ESR1 ESR NR3A1 | PPLNsVsPsPLMLLHPPPQLsPFLQPHGQQVPYYLENEPSG |
| P03372 | S167 | ELM|EPSD | ESR1 ESR NR3A1 | PAFYRPNsDNRRQGGRERLAsTNDKGSMAMESAKETRYCAV |
| P04075 | S132 | Sugiyama | ALDOA ALDA | GVVPLAGtNGEtttQGLDGLsERCAQYKKDGADFAKWRCVL |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T344 | Sugiyama | ALDOA ALDA | AQEEYVKRALANsLACQGKytPsGQAGAAAsEsLFVsNHAy |
| P04083 | S182 | Sugiyama | ANXA1 ANX1 LPC1 | RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD |
| P04083 | S189 | Sugiyama | ANXA1 ANX1 LPC1 | tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04632 | S88 | Sugiyama | CAPNS1 CAPN4 CAPNS | AISEAAAQYNPEPPPPRtHysNIEANEsEEVRQFRRLFAQL |
| P04632 | T85 | Sugiyama | CAPNS1 CAPN4 CAPNS | VIsAISEAAAQYNPEPPPPRtHysNIEANEsEEVRQFRRLF |
| P04792 | S78 | Sugiyama | HSPB1 HSP27 HSP28 | LPPAAIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVs |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P04792 | S86 | Sugiyama | HSPB1 HSP27 HSP28 | PAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAP |
| P05023 | S519 | Sugiyama | ATP1A1 | sEPQHLLVMKGAPERILDRCssILLHGKEQPLDEELKDAFQ |
| P05386 | S101 | Sugiyama | RPLP1 RRP1 | APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S102 | Sugiyama | RPLP2 D11S2243E RPP2 | PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S29 | Sugiyama | RPLP2 D11S2243E RPP2 | LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK |
| P05783 | S305 | Sugiyama | KRT18 CYK18 PIG46 | QSAEVGAAETTLTELRRtVQsLEIDLDsMRNLKAsLENsLR |
| P05783 | S93 | Sugiyama | KRT18 CYK18 PIG46 | GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR |
| P05787 | S330 | Sugiyama | KRT8 CYK8 | MNRNISRLQAEIEGLKGQRAsLEAAIADAEQRGELAIKDAN |
| P05787 | S475 | Sugiyama | KRT8 CYK8 | TSSSRAVVVKKIETRDGKLVsEssDVLPK____________ |
| P06493 | S39 | Sugiyama | CDK1 CDC2 CDC28A CDKN1 P34CDC2 | yKGRHKTTGQVVAMKKIRLEsEEEGVPstAIREIsLLKELR |
| P06733 | S291 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | S320 | Sugiyama | LDHB | GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______ |
| P07195 | S44 | Sugiyama | LDHB | ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM |
| P07195 | T302 | Sugiyama | LDHB | YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD |
| P07205 | S393 | Sugiyama | PGK2 PGKB | GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA |
| P07205 | S399 | Sugiyama | PGK2 PGKB | CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__ |
| P07237 | S357 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | ERItEFCHRFLEGKIKPHLMsQELPEDWDKQPVKVLVGKNF |
| P07237 | S427 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | WDKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFP |
| P07339 | S37 | Sugiyama | CTSD CPSD | PASALVRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQ |
| P07339 | S42 | Sugiyama | CTSD CPSD | VRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQAVPAV |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07437 | S75 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07814 | S1336 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | SEEDKEALIAKCNDYRRRLLsVNIRVRADLRDNysPGWKFN |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07814 | S880 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | LKAQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPE |
| P07814 | S954 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | ELLQLKAQYKsLIGVEyKPVsATGAEDKDKKKKEKENKSEK |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07900 | S391 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P07900 | S460 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | QFSKNIKLGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDY |
| P07900 | S468 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | GIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQ |
| P07900 | S50 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL |
| P07900 | S63 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN |
| P07900 | S68 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | LIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQDRt |
| P07942 | S1115 | Sugiyama | LAMB1 | SCNEFTGQCQCMPGFGGRTCsECQELFWGDPDVECRACDCD |
| P08174 | S106 | Sugiyama | CD55 CR DAF | QWSDIEEFCNRSCEVPtRLNsAsLKQPYITQNyFPVGtVVE |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08238 | S383 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S452 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AFSKNLKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEy |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S58 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| P08238 | S63 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERt |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | Y457 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK |
| P08670 | S325 | Sugiyama | VIM | NNDALRQAKQESTEYRRQVQsLtCEVDALKGtNEsLERQMR |
| P08758 | T8 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | _____________MAQVLRGtVtDFPGFDERADAEtLRKAM |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09496 | S236 | Sugiyama | CLTA | RLCDFNPKSSKQAKDVSRMRsVLIsLKQAPLVH________ |
| P09496 | S240 | Sugiyama | CLTA | FNPKSSKQAKDVSRMRsVLIsLKQAPLVH____________ |
| P09651 | S95 | Sugiyama | HNRNPA1 HNRPA1 | RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| P09661 | S236 | Sugiyama | SNRPA1 | EVERLKGLLQsGQIPGRERRsGPtDDGEEEMEEDtVtNGS_ |
| P09972 | S132 | Sugiyama | ALDOC ALDC | GVVPLAGtDGEtttQGLDGLsERCAQYKKDGADFAKWRCVL |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG41 | S140 | Sugiyama | CTAGE8 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| P0CG47 | S57 | Sugiyama | UBB | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P0CG48 | S57 | Sugiyama | UBC | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | S54 | Sugiyama | TUBA3C TUBA2 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P10809 | S398 | Sugiyama | HSPD1 HSP60 | LDVttsEyEKEKLNERLAKLsDGVAVLKVGGtsDVEVNEKK |
| P10809 | S488 | Sugiyama | HSPD1 HSP60 | IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG |
| P11047 | T332 | Sugiyama | LAMC1 LAMB2 | YGVDCEKCLPFFNDRPWRRAtAEsASECLPCDCNGRsQECy |
| P11142 | S221 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | GGGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHF |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | S544 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KYKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKIND |
| P11274 | S371 | Sugiyama | BCR BCR1 D22S11 | SRVsPsPTTyRMFRDKsRsPsQNsQQsFDSssPPtPQCHKR |
| P11532 | S3623 | Sugiyama | DMD | EAKVNGttVssPstsLQRsDssQPMLLRVVGSQTSDSMGEE |
| P11586 | S318 | Sugiyama | MTHFD1 MTHFC MTHFD | FKPGKWMIQYNNLNLKTPVPsDIDIsRSCKPKPIGKLAREI |
| P11717 | S2479 | Sugiyama | IGF2R MPRI | ARKGKSSSAQQKTVSStKLVsFHDDsDEDLLHI________ |
| P11831 | S103 | ELM|EPSD | SRF | sEsGEEEELGAERRGLKRsLsEMEIGMVVGGPEASAAATGG |
| P12268 | S416 | Sugiyama | IMPDH2 IMPD2 | APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK |
| P12814 | S404 | Sugiyama | ACTN1 | NEIRRLERLDHLAEKFRQKAsIHEAWtDGKEAMLRQKDyEt |
| P13010 | T715 | Sugiyama | XRCC5 G22P2 | sVtAEEAKKFLAPKDKPsGDtAAVFEEGGDVDDLLDMI___ |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S732 | Sugiyama | EEF2 EF2 | DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP |
| P13639 | Y730 | Sugiyama | EEF2 EF2 | HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ |
| P13667 | S468 | Sugiyama | PDIA4 ERP70 ERP72 | ytFAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAM |
| P13667 | S470 | Sugiyama | PDIA4 ERP70 ERP72 | FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP |
| P13798 | S27 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | LsEPEEAAALyRGLSRQPALsAACLGPEVtTQyGGQyRTVH |
| P13798 | S8 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | _____________MERQVLLsEPEEAAALyRGLSRQPALsA |
| P13804 | S192 | Sugiyama | ETFA | sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL |
| P13861 | S58 | Sugiyama | PRKAR2A PKR2 PRKAR2 | TRLREARAPAsVLPAAtPRQsLGHPPPEPGPDRVADAKGDs |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S205 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD |
| P14618 | S55 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | IDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMNVARLN |
| P14618 | S97 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP |
| P14618 | T95 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | NFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTK |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S514 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK |
| P14625 | S64 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR |
| P14625 | S746 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | GyLLPDTKAYGDRIERMLRLsLNIDPDAKVEEEPEEEPEET |
| P14866 | S471 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | VCVSKQPAIMPGQSyGLEDGsCsyKDFSESRNNRFstPEQA |
| P14866 | S544 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH |
| P15104 | S322 | Sugiyama | GLUL GLNS | GFHETSNINDFSAGVANRsAsIRIPRTVGQEKKGYFEDRRP |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15311 | S536 | Sugiyama | EZR VIL2 | KRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNE |
| P15311 | S539 | Sugiyama | EZR VIL2 | TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR |
| P15531 | S120 | Sugiyama | NME1 NDPKA NM23 | KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P16220 | S119 | PSP | CREB1 | EsVDsVTDsQKRREILsRRPsYRKILNDLssDAPGVPRIEE |
| P16333 | S85 | Sugiyama | NCK1 NCK | ASIVKNLKDTLGIGKVKRKPsVPDsAsPADDsFVDPGERLy |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17676 | T235 | GPS6|EPSD | CEBPB TCF5 PP9092 | AVPsGssGsLstsssssPPGtPsPADAKAPPTACyAGAAPA |
| P17676 | T266 | GPS6|EPSD | CEBPB TCF5 PP9092 | TACyAGAAPAPsQVKSKAKKtVDKHSDEYKIRRERNNIAVR |
| P17812 | S573 | Sugiyama | CTPS1 CTPS | HYLQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD__ |
| P17812 | S587 | Sugiyama | CTPS1 CTPS | ysDRsGsssPDsEItELKFPsINHD________________ |
| P17987 | S372 | Sugiyama | TCP1 CCT1 CCTA | VQERICDDELILIKNTKARTsAsIILRGANDFMCDEMERSL |
| P17987 | S544 | Sugiyama | TCP1 CCT1 CCTA | ILRIDDLIKLHPESKDDKHGsyEDAVHsGALND________ |
| P18615 | S115 | Sugiyama | NELFE RD RDBP | KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs |
| P18615 | S131 | Sugiyama | NELFE RD RDBP | QRsIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGE |
| P18615 | S135 | Sugiyama | NELFE RD RDBP | sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG |
| P18621 | S5 | Sugiyama | RPL17 | ________________MVRysLDPENPtKsCKSRGSNLRVH |
| P19338 | S458 | Sugiyama | NCL | TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P19338 | S580 | Sugiyama | NCL | PRGsPNARSQPSKTLFVKGLsEDttEEtLKEsFDGsVRARI |
| P19338 | Y462 | Sugiyama | NCL | AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs |
| P19634 | S703 | ELM | SLC9A1 APNH1 NHE1 | yLtVPAHKLDsPtMsRARIGsDPLAyEPKEDLPVItIDPAs |
| P20042 | S67 | Sugiyama | EIF2S2 EIF2B | EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK |
| P20290 | S173 | Sugiyama | BTF3 NACB OK/SW-cl.8 | QLGADsLtsLRRLAEALPKQsVDGKAPLAtGEDDDDEVPDL |
| P20618 | S162 | Sugiyama | PSMB1 PSC5 | DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG |
| P21333 | S2152 | ELM|Sugiyama | FLNA FLN FLN1 | VKVTGEGRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQ |
| P21333 | S2158 | Sugiyama | FLNA FLN FLN1 | GRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQDMtAQV |
| P22033 | S481 | Sugiyama | MMUT MUT | EGIPKLRIEECAARRQARIDsGSEVIVGVNKYQLEKEDAVE |
| P22059 | S379 | Sugiyama | OSBP OSBP1 | FFDAPEIITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLE |
| P22090 | S204 | Sugiyama | RPS4Y1 RPS4Y PRO2646 | IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN |
| P22314 | S46 | Sugiyama | UBA1 A1S9T UBE1 | AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA |
| P22314 | S820 | Sugiyama | UBA1 A1S9T UBE1 | tPKsGVKIHVsDQELQsANAsVDDsRLEELKATLPsPDKLP |
| P22626 | S189 | Sugiyama | HNRNPA2B1 HNRPA2B1 | IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF |
| P22736 | S351 | SIGNOR|EPSD | NR4A1 GFRP1 HMR NAK1 | GMVKEVVRTDsLKGRRGRLPsKPKQPPDAsPANLLtSLVRA |
| P23142 | S246 | Sugiyama | FBLN1 PP213 | SCRLGESCINTVGSFRCQRDssCGtGYELTEDNSCKDIDEC |
| P23381 | S351 | Sugiyama | WARS1 IFI53 WARS WRS | KPALLHSTFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTK |
| P23381 | S358 | Sugiyama | WARS1 IFI53 WARS WRS | TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs |
| P23588 | S207 | Sugiyama | EIF4B | DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR |
| P23588 | S422 | EPSD | EIF4B | ERHPsWRsEEtQERERsRtGsEssQtGtstTssRNARRREs |
| P24534 | S141 | Sugiyama | EEF1B2 EEF1B EF1B | ERLAQYESKKAKKPALVAKssILLDVKPWDDEtDMAKLEEC |
| P25054 | S1861 | Sugiyama | APC DP2.5 | DsPHHytPIEGTPYCFsRNDsLssLDFDDDDVDLSREKAEL |
| P25205 | S447 | Sugiyama | MCM3 | EQGRVTIAKAGIHARLNARCsVLAAANPVyGRyDQyKTPME |
| P25705 | S76 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV |
| P25788 | Y239 | Sugiyama | PSMA3 HC8 PSC8 | ELTNGRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM____ |
| P25963 | S32 | SIGNOR|EPSD | NFKBIA IKBA MAD3 NFKBI | AMEGPRDGLKKERLLDDRHDsGLDsMKDEEyEQMVKELQEI |
| P26038 | S527 | Sugiyama | MSN | ERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHAE |
| P26038 | S576 | Sugiyama | MSN | YKtLRQIRQGNTKQRIDEFEsM___________________ |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | T107 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF |
| P26639 | S702 | Sugiyama | TARS1 TARS | ISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEE |
| P26885 | S108 | Sugiyama | FKBP2 FKBP13 | GWDQGLLGMCEGEKRKLVIPsELGyGERGAPPKIPGGATLV |
| P27708 | S1859 | Sugiyama | CAD | RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP |
| P27824 | S362 | Sugiyama | CANX | WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK |
| P28066 | S172 | Sugiyama | PSMA5 | QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK |
| P28066 | S174 | Sugiyama | PSMA5 | FHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEA |
| P29353 | S426 | Sugiyama | SHC1 SHC SHCA | VRKQMPPPPPCPGRELFDDPsyVNVQNLDKARQAVGGAGPP |
| P29353 | Y427 | Sugiyama | SHC1 SHC SHCA | RKQMPPPPPCPGRELFDDPsyVNVQNLDKARQAVGGAGPPN |
| P29401 | S104 | Sugiyama | TKT | AVWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGs |
| P29401 | S105 | Sugiyama | TKT | VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL |
| P29401 | S190 | Sugiyama | TKT | ASIYKLDNLVAILDINRLGQsDPAPLQHQMDIyQKRCEAFG |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | S305 | Sugiyama | TKT | LAtPPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQAL |
| P29401 | S473 | Sugiyama | TKT | AtEKAVELAANTKGICFIRTsRPENAIIyNNNEDFQVGQAK |
| P29401 | T444 | Sugiyama | TKT | DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S86 | Sugiyama | EEF1D EF1D | GPGAssGtsGDHGELVVRIAsLEVENQsLRGVVQELQQAIs |
| P30043 | S198 | Sugiyama | BLVRB FLR SCAN | KHDLGHFMLRCLttDEyDGHstyPsHQyQ____________ |
| P30048 | S199 | Sugiyama | PRDX3 AOP1 | SGLALRGLFIIDPNGVIKHLsVNDLPVGRSVEETLRLVKAF |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30050 | S157 | Sugiyama | RPL12 | QsVGCNVDGRHPHDIIDDINsGAVECPAs____________ |
| P30084 | S186 | Sugiyama | ECHS1 | LIGtIPGAGGtQRLTRAVGKsLAMEMVLTGDRISAQDAKQA |
| P30085 | S180 | Sugiyama | CMPK1 CMK CMPK UCK UMK UMPK | KPIIDLyEEMGKVKKIDASKsVDEVFDEVVQIFDKEG____ |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | T51 | Sugiyama | PEBP1 PBP PEBP | GAAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDP |
| P30101 | S367 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KALERFLQDyFDGNLKRyLKsEPIPESNDGPVKVVVAENFD |
| P30101 | Y364 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | RDGKALERFLQDyFDGNLKRyLKsEPIPESNDGPVKVVVAE |
| P30533 | S242 | Sugiyama | LRPAP1 A2MRAP | TELKEKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWD |
| P31946 | S132 | Sugiyama | YWHAB | TQPESKVFyLKMKGDYFRyLsEVAsGDNKQTtVsNsQQAyQ |
| P31948 | S16 | Sugiyama | STIP1 | _____MEQVNELKEKGNKALsVGNIDDALQCysEAIKLDPH |
| P32004 | S1152 | SIGNOR|iPTMNet|EPSD | L1CAM CAML1 MIC5 | LLLLVLLILCFIKRSKGGKysVKDKEDtQVDsEARPMKDEt |
| P32119 | S112 | Sugiyama | PRDX2 NKEFB TDPX1 | KEGGLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFII |
| P32119 | S151 | Sugiyama | PRDX2 NKEFB TDPX1 | IIDGKGVLRQItVNDLPVGRsVDEALRLVQAFQYTDEHGEV |
| P33176 | S57 | Sugiyama | KIF5B KNS KNS1 | DTVVIASKPYAFDRVFQSsTsQEQVyNDCAKKIVKDVLEGy |
| P33316 | S120 | Sugiyama | DUT | PsKRARPAEVGGMQLRFARLsEHAtAPTRGsARAAGYDLYS |
| P33316 | S130 | Sugiyama | DUT | GGMQLRFARLsEHAtAPTRGsARAAGYDLYSAYDYTIPPME |
| P33316 | S164 | Sugiyama | DUT | YTIPPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDV |
| P33993 | S392 | Sugiyama | MCM7 CDC47 MCM2 | RGNINICLMGDPGVAKSQLLsyIDRLAPRSQYTTGRGssGV |
| P34897 | S50 | Sugiyama | SHMT2 | NAAQTQTGEANRGWtGQEsLsDsDPEMWELLQREKDRQCRG |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34932 | S363 | Sugiyama | HSPA4 APG2 HSPH2 | GATRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAIL |
| P34932 | S76 | Sugiyama | HSPA4 APG2 HSPH2 | VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT |
| P35221 | S641 | Sugiyama | CTNNA1 | GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD |
| P35269 | T154 | Sugiyama | GTF2F1 RAP74 | AFEAFPVHNWYNFTPLARHRtLtAEEAEEEWERRNKVLNHF |
| P35568 | S1101 | GPS6 | IRS1 | RNQSAKVIRADPQGCRRRHssEtFsstPSATRVGNTVPFGA |
| P35579 | S1304 | Sugiyama | MYH9 | NVtGLLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQK |
| P35579 | S169 | Sugiyama | MYH9 | HIyAITDtAyRSMMQDREDQsILCTGESGAGKTENTKKVIQ |
| P35580 | S1952 | Sugiyama | MYH10 | GPIsFsssRSGRRQLHLEGAsLELsDDDtEsKtsDVNEtQP |
| P35606 | S350 | Sugiyama | COPB2 | MGDAEIKDGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVC |
| P35613 | S228 | Sugiyama | BSG UNQ6505/PRO21383 | EPMGTANIQLHGPPRVKAVKssEHINEGEtAMLVCKSEsVP |
| P35613 | S229 | Sugiyama | BSG UNQ6505/PRO21383 | PMGTANIQLHGPPRVKAVKssEHINEGEtAMLVCKSEsVPP |
| P35659 | S301 | Sugiyama | DEK | NVKKADSSTTKKNQNSSKKEsEsEDssDDEPLIKKLKKPPT |
| P36551 | S112 | Sugiyama | CPOX CPO CPX | AFGHVQRAEMLPKTSGTRAtsLGRPEEEEDELAHRCSSFMA |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P36578 | T84 | Sugiyama | RPL4 RPL1 | AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP |
| P37802 | S163 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37837 | S13 | Sugiyama | TALDO1 TAL TALDO TALDOR | ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA |
| P38646 | S148 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | YDDPEVQKDIKNVPFKIVRAsNGDAWVEAHGKLYSPSQIGA |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P39023 | S265 | Sugiyama | RPL3 OK/SW-cl.32 | HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY |
| P39023 | S304 | Sugiyama | RPL3 OK/SW-cl.32 | IYKIGQGyLIKDGKLIKNNAstDyDLSDKSINPLGGFVHYG |
| P41567 | T46 | Sugiyama | EIF1 SUI1 | GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK |
| P42345 | S2448 | EPSD | MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1 | NWRLMDTNTKGNKRsRtRtDsYsAGQsVEILDGVELGEPAH |
| P42345 | T2446 | EPSD | MTOR FRAP FRAP1 FRAP2 RAFT1 RAPT1 | LLNWRLMDTNTKGNKRsRtRtDsYsAGQsVEILDGVELGEP |
| P42566 | S746 | Sugiyama | EPS15 AF1P | DFSTLSKVNNEDPFRSATSssVsNVVITKNVFEETSVKSED |
| P42677 | S78 | Sugiyama | RPS27 MPS1 | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| P43243 | S188 | Sugiyama | MATR3 KIAA0723 | EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs |
| P43243 | S195 | Sugiyama | MATR3 KIAA0723 | RDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyD |
| P43243 | S234 | Sugiyama | MATR3 KIAA0723 | yDRMDyEDDRLRDGERCRDDsFFGEtsHNyHKFDsEyERMG |
| P43354 | S347 | EPSD | NR4A2 NOT NURR1 TINUR | GMVKEVVRTDsLKGRRGRLPsKPKsPQEPsPPsPPVSLISA |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P43490 | S472 | Sugiyama | NAMPT PBEF PBEF1 | EYGQDLLHTVFKNGKVTKsysFDEIRKNAQLNIELEAAHH_ |
| P45974 | S783 | Sugiyama | USP5 ISOT | IDDLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQL |
| P46060 | S454 | Sugiyama | RANGAP1 KIAA1835 SD | VstFLAFPsPEKLLRLGPKssVLIAQQTDTSDPEKVVSAFL |
| P46527 | T198 | ELM|EPSD | CDKN1B KIP1 p27 | sPNAGSVEQtPKKPGLRRRQt____________________ |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46937 | T110 | Sugiyama | YAP1 YAP65 | KLPDsFFKPPEPKsHsRQAstDAGtAGALtPQHVRAHssPA |
| P46937 | T114 | Sugiyama | YAP1 YAP65 | sFFKPPEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQL |
| P47712 | S415 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | SAFSILFNRVLGVSGSQsRGstMEEELENIttKHIVsNDss |
| P47712 | S727 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP |
| P47712 | T416 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | AFSILFNRVLGVSGSQsRGstMEEELENIttKHIVsNDssD |
| P47756 | S192 | Sugiyama | CAPZB | TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P49327 | S1129 | Sugiyama | FASN FAS | QQVPILEKFCFtPHTEEGCLsERAALQEELQLCKGLVQALQ |
| P49419 | S84 | Sugiyama | ALDH7A1 ATQ1 | EVIttyCPANNEPIARVRQAsVADyEEtVKKAREAWKIWAD |
| P49815 | S1798 | ELM|EPSD | TSC2 TSC4 | AQTPAEPTPGyEVGQRKRLIssVEDFTEFV___________ |
| P49815 | S939 | GPS6 | TSC2 TSC4 | NVLLsFDDtPEKDsFRARsTsLNERPKSLRIARPPKQGLNN |
| P49815 | T1462 | GPS6 | TSC2 TSC4 | EGPLPsssPRsPsGLRPRGYtIsDsAPsRRGKRVERDALKS |
| P49841 | S9 | ELM | GSK3B | ____________MSGRPRttsFAEsCKPVQQPsAFGsMKVS |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50454 | S141 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI |
| P50549 | S191 | EPSD | ETV1 ER81 | PSQSIPDSSYPMDHRFRRQLsEPCNSFPPLPTMPREGRPMY |
| P50549 | S216 | EPSD | ETV1 ER81 | SFPPLPTMPREGRPMYQRQMsEPNIPFPPQGFKQEYHDPVY |
| P50549 | S334 | EPSD | ETV1 ER81 | GDIKQEPGMYREGPTYQRRGsLQLWQFLVALLDDPSNSHFI |
| P51116 | S601 | Sugiyama | FXR2 FMR1L2 | RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ |
| P51812 | S432 | Sugiyama | RPS6KA3 ISPK1 MAPKAPK1B RSK2 | HRNsIQFTDGYEVKEDIGVGsysVCKRCIHKATNMEFAVKI |
| P51812 | S434 | Sugiyama | RPS6KA3 ISPK1 MAPKAPK1B RSK2 | NsIQFTDGYEVKEDIGVGsysVCKRCIHKATNMEFAVKIID |
| P51812 | S66 | Sugiyama | RPS6KA3 ISPK1 MAPKAPK1B RSK2 | SIKEIAITHHVKEGHEKADPsQFELLKVLGQGsFGKVFLVK |
| P51812 | Y433 | Sugiyama | RPS6KA3 ISPK1 MAPKAPK1B RSK2 | RNsIQFTDGYEVKEDIGVGsysVCKRCIHKATNMEFAVKII |
| P51858 | S107 | Sugiyama | HDGF HMG1L2 | WEIENNPtVKASGYQSsQKKsCVEEPEPEPEAAEGDGDKKG |
| P51858 | S83 | Sugiyama | HDGF HMG1L2 | LFPyEEsKEKFGKPNKRKGFsEGLWEIENNPtVKASGYQSs |
| P51858 | T94 | Sugiyama | HDGF HMG1L2 | GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP |
| P52298 | S13 | Sugiyama | NCBP2 CBP20 PIG55 | ________MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQE |
| P53355 | S289 | ELM|EPSD | DAPK1 DAPK | SLQHPWIKPKDTQQALSRKAsAVNMEKFKKFAARKKWKQsV |
| P53365 | S260 | Sugiyama | ARFIP2 POR1 | TDLEELsLGPRDAGTRGRLEsAQATFQAHRDKYEKLRGDVA |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P53621 | S266 | Sugiyama | COPA | RGHyNNVSCAVFHPRQELILsNsEDKSIRVWDMSKRTGVQT |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P53999 | S57 | Sugiyama | SUB1 PC4 RPO2TC1 | VKKQKTGETsRALsssKQssssRDDNMFQIGKMRYVSVRDF |
| P54253 | S775 | PSP | ATXN1 ATX1 SCA1 | APFLTKIEPSKPAATRKRRWsAPESRKLEKSEDEPPLTLPK |
| P54652 | S224 | Sugiyama | HSPA2 | GGGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHL |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P55036 | S358 | Sugiyama | PSMD4 MCB1 | VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_ |
| P55060 | S342 | Sugiyama | CSE1L CAS XPO2 | ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF |
| P55072 | S718 | Sugiyama | VCP HEL-220 HEL-S-70 | AIREsIEsEIRRERERQtNPsAMEVEEDDPVPEIRRDHFEE |
| P56537 | S6 | Sugiyama | EIF6 EIF3A ITGB4BP OK/SW-cl.27 | _______________MAVRAsFENNCEIGCFAKLTNTYCLV |
| P57053 | S37 | Sugiyama | H2BC12L H2BFS H2BS1 | KAVTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| P57721 | S82 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK |
| P57721 | T159 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | sQCGsLIGKGGSKIKEIREstGAQVQVAGDMLPNstERAVT |
| P58876 | S37 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | Y53 | Sugiyama | ACTB | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P60983 | T27 | ELM|EPSD | GMFB | VCDVAEDLVEKLRKFRFRKEtNNAAIIMKIDKDKRLVVLDE |
| P61081 | S175 | Sugiyama | UBE2M UBC12 | NNRRLFEQNVQRSMRGGyIGstyFERCLK____________ |
| P61247 | S236 | Sugiyama | RPS3A FTE1 MFTL | KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61313 | S100 | Sugiyama | RPL15 EC45 TCBAP0781 | tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW |
| P61353 | S86 | Sugiyama | RPL27 | SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL |
| P61916 | S29 | Sugiyama | NPC2 HE1 | LLLALSTAAQAEPVQFKDCGsVDGVIKEVNVsPCPtQPCQL |
| P61962 | S38 | Sugiyama | DCAF7 HAN11 WDR68 | TVYAMNWSVRPDKRFRLALGsFVEEYNNKVQLVGLDEESSE |
| P61978 | S417 | Sugiyama | HNRNPK HNRPK | DLAGsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITI |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P62081 | T121 | Sugiyama | RPS7 | LPKPTRKSRTKNKQKRPRsRtLtAVHDAILEDLVFPsEIVG |
| P62081 | T123 | Sugiyama | RPS7 | KPTRKSRTKNKQKRPRsRtLtAVHDAILEDLVFPsEIVGKR |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62263 | S137 | Sugiyama | RPS14 PRO2640 | RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______ |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62277 | S12 | Sugiyama | RPS13 | _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD |
| P62304 | S89 | Sugiyama | SNRPE | KSRKQLGRIMLKGDNITLLQsVsN_________________ |
| P62333 | S244 | Sugiyama | PSMC6 SUG2 | DHQPCIIFMDEIDAIGGRRFsEGTSADREIQRTLMELLNQM |
| P62701 | S204 | Sugiyama | RPS4X CCG2 RPS4 SCAR | tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | Y55 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P62753 | S148 | Sugiyama | RPS6 OK/SW-cl.2 | tVPRRLGPKRASRIRKLFNLsKEDDVRQyVVRKPLNKEGKK |
| P62753 | S235 | ELM|EPSD | RPS6 OK/SW-cl.2 | KRMKEAKEKRQEQIAKRRRLssLRAstsKsEssQK______ |
| P62753 | S236 | ELM|EPSD | RPS6 OK/SW-cl.2 | RMKEAKEKRQEQIAKRRRLssLRAstsKsEssQK_______ |
| P62807 | S37 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | KAVTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIss |
| P62899 | S15 | Sugiyama | RPL31 | ______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG |
| P62906 | S64 | Sugiyama | RPL10A NEDD6 | QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62937 | S21 | Sugiyama | PPIA CYPA | MVNPTVFFDIAVDGEPLGRVsFELFADKVPKtAENFRALST |
| P62937 | T157 | Sugiyama | PPIA CYPA | NIVEAMERFGsRNGKTSKKItIADCGQLE____________ |
| P62979 | S123 | Sugiyama | RPS27A UBA80 UBCEP1 | LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK |
| P62979 | S57 | Sugiyama | RPS27A UBA80 UBCEP1 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA |
| P62987 | S57 | Sugiyama | UBA52 UBCEP2 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI |
| P63104 | T30 | Sugiyama | YWHAZ | AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | Y53 | Sugiyama | ACTG1 ACTG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | Y54 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P67809 | S102 | Sugiyama | YBX1 NSEP1 YB1 | EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA |
| P67809 | S136 | Sugiyama | YBX1 NSEP1 YB1 | GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR |
| P67809 | S209 | Sugiyama | YBX1 NSEP1 YB1 | RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ |
| P67809 | T108 | Sugiyama | YBX1 NSEP1 YB1 | QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP |
| P67809 | Y99 | Sugiyama | YBX1 NSEP1 YB1 | DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | Y55 | Sugiyama | ACTC1 ACTC | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | Y55 | Sugiyama | ACTA1 ACTA | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68363 | S439 | Sugiyama | TUBA1B | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | S54 | Sugiyama | TUBA1B | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T82 | Sugiyama | TUBA1B | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| P68400 | T13 | Sugiyama | CSNK2A1 CK2A1 | ________MSGPVPSRARVytDVNTHRPREYWDYESHVVEW |
| P78345 | S253 | Sugiyama | RPP38 | DtsFEDLsKPKRKLADGRQAsVtLQPLKIKKLIPNPNKIRK |
| P78362 | S494 | Sugiyama | SRPK2 | GSPLTEQEESSPSHDRSRtVsAsstGDLPKAKTRAADLLVN |
| P78371 | S143 | Sugiyama | CCT2 99D8.1 CCTB | PQTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIA |
| P78371 | S144 | Sugiyama | CCT2 99D8.1 CCTB | QTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIAG |
| P78371 | S470 | Sugiyama | CCT2 99D8.1 CCTB | IADNAGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAI |
| P83731 | S7 | Sugiyama | RPL24 | ______________MKVELCsFsGyKIYPGHGRRYARTDGK |
| P83731 | S86 | Sugiyama | RPL24 | EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE |
| P83731 | T83 | Sugiyama | RPL24 | QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA |
| P84098 | S12 | Sugiyama | RPL19 | _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI |
| Q00587 | S350 | Sugiyama | CDC42EP1 BORG5 CEP1 MSE55 | HyPEMDARQERVEVLPQARAsWEsLDEEWRAPQAGsRtPVP |
| Q00610 | S146 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | AVYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLL |
| Q00610 | S1483 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | VNEsLNNLFITEEDyQALRTsIDAyDNFDNIsLAQRLEKHE |
| Q00613 | S375 | Sugiyama | HSF1 HSTF1 | TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL |
| Q01105 | S161 | Sugiyama | SET | FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q02543 | S123 | Sugiyama | RPL18A | AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK |
| Q02790 | S11 | Sugiyama | FKBP4 FKBP52 | __________MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDE |
| Q02790 | S15 | Sugiyama | FKBP4 FKBP52 | ______MTAEEMKAtEsGAQsAPLPMEGVDIsPKQDEGVLK |
| Q02790 | S78 | Sugiyama | FKBP4 FKBP52 | TGWLLDGTKFDSSLDRKDKFsFDLGKGEVIKAWDIAIATMK |
| Q02818 | S193 | Sugiyama | NUCB1 NUC | HEEFKRyEMLKEHERRRyLEsLGEEQRKEAERKLEEQQRRH |
| Q04917 | S145 | Sugiyama | YWHAH YWHA1 | KMKGDYYRYLAEVASGEKKNsVVEAsEAAyKEAFEISKEQM |
| Q06210 | S261 | Sugiyama | GFPT1 GFAT GFPT | GsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDA |
| Q06830 | S152 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV |
| Q06830 | T143 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF |
| Q06830 | T156 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG |
| Q07021 | S106 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | LsDEIKEERKIQKHKTLPKMsGGWELELNGTEAKLVRKVAG |
| Q07021 | S213 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | VGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDSLDW |
| Q08209 | S492 | Sugiyama | PPP3CA CALNA CNA | EAKGLDRINERMPPRRDAMPsDANLNsINKALTSETNGTDS |
| Q08378 | S465 | Sugiyama | GOLGA3 | LSTKLQAQVECSHSSQQRQDsLsSEVDTLKQsCWDLERAMT |
| Q08AD1 | S1313 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | sLNtGDNEsVHsGKRtPRsEsVEGFLsPsRCGsRNGEKDWE |
| Q09028 | S146 | Sugiyama | RBBP4 RBAP48 | EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE |
| Q09161 | S22 | Sugiyama | NCBP1 CBP80 NCBP | SRRRHsDENDGGQPHKRRKtsDANEtEDHLEsLICKVGEKS |
| Q09666 | S135 | Sugiyama | AHNAK PM227 | sGDDEEyQRIYttKIKPRLKsEDGVEGDLGEtQsRTITVTR |
| Q12789 | S844 | Sugiyama | GTF3C1 | SFISERRTIKQESGRAGVRPsssGsAWEACSEAPSKGSQDG |
| Q12789 | S845 | Sugiyama | GTF3C1 | FISERRTIKQESGRAGVRPsssGsAWEACSEAPSKGSQDGV |
| Q12789 | S846 | Sugiyama | GTF3C1 | ISERRTIKQESGRAGVRPsssGsAWEACSEAPSKGSQDGVT |
| Q13085 | S1766 | Sugiyama | ACACA ACAC ACC1 ACCA | KGYRYLYLTPQDYKRVsALNsVHCEHVEDEGESRYKITDII |
| Q13098 | S474 | Sugiyama | GPS1 COPS1 CSN1 | MLRAAVLRNQIHVKsPPREGsQGELtPANsQsRMstNM___ |
| Q13247 | S297 | Sugiyama | SRSF6 SFRS6 SRP55 | RSRSPKENGKGDIKsKSRsRsQsRsNsPLPVPPsKARsVsP |
| Q13247 | S299 | Sugiyama | SRSF6 SFRS6 SRP55 | RSPKENGKGDIKsKSRsRsQsRsNsPLPVPPsKARsVsPPP |
| Q13263 | S471 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | FGsGDDPyssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLE |
| Q13263 | S473 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | sGDDPyssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERL |
| Q13283 | S67 | Sugiyama | G3BP1 G3BP | sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN |
| Q13283 | T71 | Sugiyama | G3BP1 G3BP | PADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLNDGVV |
| Q13347 | S301 | Sugiyama | EIF3I EIF3S2 TRIP1 | VKGHFGPINSVAFHPDGKSYssGGEDGyVRIHYFDPQYFEF |
| Q13442 | S176 | Sugiyama | PDAP1 HASPP28 | KKEEERKAKDDATLsGKRMQsLsLNK_______________ |
| Q13442 | S19 | Sugiyama | PDAP1 HASPP28 | __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE |
| Q13442 | S63 | Sugiyama | PDAP1 HASPP28 | GGDGAAGDPKKEKKsLDsDEsEDEEDDyQQKRKGVEGLIDI |
| Q13442 | T18 | Sugiyama | PDAP1 HASPP28 | ___MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEE |
| Q13501 | S28 | Sugiyama | SQSTM1 ORCA OSIL | AYLLGKEDAAREIRRFsFCCsPEPEAEAEAAAGPGPCERLL |
| Q13509 | S75 | Sugiyama | TUBB3 TUBB4 | SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS |
| Q13561 | S83 | Sugiyama | DCTN2 DCTN50 | GTKGLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKY |
| Q13561 | T79 | Sugiyama | DCTN2 DCTN50 | DKRVGTKGLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETP |
| Q13885 | S75 | Sugiyama | TUBB2A TUBB2 | AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q14135 | S59 | Sugiyama | VGLL4 KIAA0121 | SALsSHRTGPPPIsPSKRKFsMEPGDEDLDCDNDHVSKMSR |
| Q14152 | S1028 | Sugiyama | EIF3A EIF3S10 KIAA0139 | NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP |
| Q14152 | S492 | Sugiyama | EIF3A EIF3S10 KIAA0139 | VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14152 | S988 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN |
| Q14155 | S694 | Sugiyama | ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314 | SKsPKTMKKLLPKRKPERKPsDEEFASRKstAALEEDAQIL |
| Q14155 | T704 | Sugiyama | ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314 | LPKRKPERKPsDEEFASRKstAALEEDAQILKVIEAYCTSA |
| Q14204 | T695 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | NHVEGQKLKQDGDsFRMKLNtQEIFDDWARKVQQRNLGVSG |
| Q14257 | S284 | Sugiyama | RCN2 ERC55 | AQEEALHLIDEMDLNGDKKLsEEEILENPDLFLtsEAtDyG |
| Q14257 | T297 | Sugiyama | RCN2 ERC55 | LNGDKKLsEEEILENPDLFLtsEAtDyGRQLHDDyFyHDEL |
| Q14498 | S334 | Sugiyama | RBM39 HCC1 RNPC2 | FELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtT |
| Q14568 | S50 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL |
| Q14697 | S190 | Sugiyama | GANAB G2AN KIAA0088 | VNARGLLEFEHQRAPRVsQGsKDPAEGDGAQPEEtPRDGDK |
| Q14847 | S146 | Sugiyama | LASP1 MLN50 | FEKSRMGPsGGEGMEPERRDsQDGssyRRPLEQQQPHHIPt |
| Q14847 | S99 | Sugiyama | LASP1 MLN50 | ELQsQVRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsN |
| Q14934 | S676 | ELM | NFATC4 NFAT3 | KRVSRPVQVYFYVSNGRRKRsPTQSFRFLPVICKEEPLPDS |
| Q14C86 | S740 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | LPSDSEAPDLKQEERLQELEsCsGLGstSDDTDVREVSSRP |
| Q14C86 | S746 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | APDLKQEERLQELEsCsGLGstSDDTDVREVSSRPSTPGLS |
| Q14C86 | T747 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | PDLKQEERLQELEsCsGLGstSDDTDVREVSSRPSTPGLSV |
| Q15021 | S1330 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | sQRAPsAKKPSTGSRyQPLAstAsDNDFVtPEPRRTTRRHP |
| Q15021 | T1331 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | QRAPsAKKPSTGSRyQPLAstAsDNDFVtPEPRRTTRRHPN |
| Q15021 | T586 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | LGLIFKGPAASTQEKNPREstGNMVTGQTVCKNKPNMsDPE |
| Q15029 | S944 | Sugiyama | EFTUD2 KIAA0031 SNRP116 | QPAPHLAREFMIKTRRRKGLsEDVsIsKFFDDPMLLELAKQ |
| Q15042 | S676 | Sugiyama | RAB3GAP1 KIAA0066 RAB3GAP | EVLAKLGtsAEGAHLRARMQsACLLSDMESFKAANPGCSLE |
| Q15054 | S407 | Sugiyama | POLD3 KIAA0039 | LKSKTYLDGEGCIVTEKVyEsEsCtDsEEELNMKTSsVHRP |
| Q15054 | Y405 | Sugiyama | POLD3 KIAA0039 | RVLKSKTYLDGEGCIVTEKVyEsEsCtDsEEELNMKTSsVH |
| Q15056 | S21 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | MADFDtyDDRAyssFGGGRGsRGsAGGHGsRSQKELPTEPP |
| Q15056 | S24 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | FDtyDDRAyssFGGGRGsRGsAGGHGsRSQKELPTEPPytA |
| Q15084 | S156 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | KDRLGGRSGGYSSGKQGRSDsSSKKDVIELtDDsFDKNVLD |
| Q15084 | S375 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | GYPAMAAINARKMKFALLKGsFsEQGINEFLRELsFGRGst |
| Q15349 | S15 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | ______MDLSMKKFAVRRFFsVYLRRKSRSKSSSLSRLEEE |
| Q15349 | S218 | EPSD|PSP | RPS6KA2 MAPKAPK1C RSK3 | IKITDFGLSKEAIDHDKRAYsFCGtIEYMAPEVVNRRGHTQ |
| Q15349 | S360 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | GRPEDTFHFDPEFTARTPTDsPGVPPsANAHHLFRGFsFVA |
| Q15349 | S366 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | FHFDPEFTARTPTDsPGVPPsANAHHLFRGFsFVAsSLIQE |
| Q15349 | S377 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | PTDsPGVPPsANAHHLFRGFsFVAsSLIQEPsQQDLHKVPV |
| Q15349 | S381 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | PGVPPsANAHHLFRGFsFVAsSLIQEPsQQDLHKVPVHPIV |
| Q15349 | S388 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | NAHHLFRGFsFVAsSLIQEPsQQDLHKVPVHPIVQQLHGNN |
| Q15349 | S425 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | HGNNIHFTDGYEIKEDIGVGsysVCKRCVHKAtDTEYAVKI |
| Q15349 | S427 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | NNIHFTDGYEIKEDIGVGsysVCKRCVHKAtDTEYAVKIID |
| Q15349 | S44 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | SKSSSLSRLEEEGVVKEIDIsHHVKEGFEKADPsQFELLKV |
| Q15349 | S454 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | HKAtDTEYAVKIIDKSKRDPsEEIEILLRYGQHPNIITLKD |
| Q15349 | S525 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | SEREASDVLCTITKTMDYLHsQGVVHRDLKPSNILYRDESG |
| Q15349 | S57 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | VVKEIDIsHHVKEGFEKADPsQFELLKVLGQGSYGKVFLVR |
| Q15349 | S634 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | GPDDTPEEILARIGSGKyALsGGNWDsISDAAKDVVSKMLH |
| Q15349 | S640 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | EEILARIGSGKyALsGGNWDsISDAAKDVVSKMLHVDPHQR |
| Q15349 | S679 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | QRLTAMQVLKHPWVVNREYLsPNQLsRQDVHLVKGAMAAtY |
| Q15349 | S684 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | MQVLKHPWVVNREYLsPNQLsRQDVHLVKGAMAAtYFALNR |
| Q15349 | S716 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | AAtYFALNRtPQAPRLEPVLssNLAQRRGMKRLTSTRL___ |
| Q15349 | S717 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | AtYFALNRtPQAPRLEPVLssNLAQRRGMKRLTSTRL____ |
| Q15349 | S82 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | LKVLGQGSYGKVFLVRKVKGsDAGQLYAMKVLKKATLKVRD |
| Q15349 | T222 | EPSD | RPS6KA2 MAPKAPK1C RSK3 | DFGLSKEAIDHDKRAYsFCGtIEYMAPEVVNRRGHTQSADW |
| Q15349 | T437 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | IKEDIGVGsysVCKRCVHKAtDTEYAVKIIDKSKRDPsEEI |
| Q15349 | T570 | EPSD|PSP|Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | IRVCDFGFAKQLRAGNGLLMtPCytANFVAPEVLKRQGYDA |
| Q15349 | T574 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | DFGFAKQLRAGNGLLMtPCytANFVAPEVLKRQGYDAACDI |
| Q15349 | T698 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | LsPNQLsRQDVHLVKGAMAAtYFALNRtPQAPRLEPVLssN |
| Q15349 | T705 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | RQDVHLVKGAMAAtYFALNRtPQAPRLEPVLssNLAQRRGM |
| Q15349 | Y426 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | GNNIHFTDGYEIKEDIGVGsysVCKRCVHKAtDTEYAVKII |
| Q15349 | Y573 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | CDFGFAKQLRAGNGLLMtPCytANFVAPEVLKRQGYDAACD |
| Q15349 | Y631 | Sugiyama | RPS6KA2 MAPKAPK1C RSK3 | FANGPDDTPEEILARIGSGKyALsGGNWDsISDAAKDVVSK |
| Q15365 | S50 | Sugiyama | PCBP1 | GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK |
| Q15365 | T127 | Sugiyama | PCBP1 | TQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT |
| Q15366 | S50 | Sugiyama | PCBP2 | GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK |
| Q15366 | T127 | Sugiyama | PCBP2 | sQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT |
| Q15418 | S221 | ELM | RPS6KA1 MAPKAPK1A RSK1 | IKLTDFGLSKEAIDHEKKAysFCGtVEYMAPEVVNRQGHSH |
| Q15418 | S307 | Sugiyama | RPS6KA1 MAPKAPK1A RSK1 | TEAQSLLRALFKRNPANRLGsGPDGAEEIKRHVFYSTIDWN |
| Q15418 | S380 | GPS6|EPSD | RPS6KA1 MAPKAPK1A RSK1 | PKDsPGIPPsAGAHQLFRGFsFVAtGLMEDDGKPRAPQAPL |
| Q15418 | S457 | Sugiyama | RPS6KA1 MAPKAPK1A RSK1 | HKATNMEYAVKVIDKSKRDPsEEIEILLRYGQHPNIITLKD |
| Q15418 | T225 | EPSD | RPS6KA1 MAPKAPK1A RSK1 | DFGLSKEAIDHEKKAysFCGtVEYMAPEVVNRQGHSHSADW |
| Q15418 | T577 | EPSD | RPS6KA1 MAPKAPK1A RSK1 | DFGFAKQLRAENGLLMtPCytANFVAPEVLKRQGYDEGCDI |
| Q15428 | S153 | Sugiyama | SF3A2 SAP62 | LFQIDYPEIAEGIMPRHRFMsAyEQRIEPPDRRWQYLLMAA |
| Q15642 | S296 | Sugiyama | TRIP10 CIP4 STOT STP | FARPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRS |
| Q15653 | S19 | GPS6 | NFKBIB IKBB TRIP9 | __MAGVACLGKAADADEWCDsGLGsLGPDAAAPGGPGLGAE |
| Q15653 | S23 | GPS6 | NFKBIB IKBB TRIP9 | GVACLGKAADADEWCDsGLGsLGPDAAAPGGPGLGAELGPG |
| Q15785 | S45 | Sugiyama | TOMM34 URCC3 | yAEASALyGRALRVLQAQGssDPEEEsVLysNRAACHLKDG |
| Q15818 | S91 | Sugiyama | NPTX1 | TILSQKETIRELTAKLGRCEsQsTLDPGAGEARAGGGRKQP |
| Q15818 | S93 | Sugiyama | NPTX1 | LSQKETIRELTAKLGRCEsQsTLDPGAGEARAGGGRKQPGS |
| Q15831 | S428 | GPS6|ELM | STK11 LKB1 PJS | GRAPNPARKACSASSKIRRLsACKQQ_______________ |
| Q16513 | S582 | Sugiyama | PKN2 PRK2 PRKCL2 | tVTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQD |
| Q16513 | S583 | Sugiyama | PKN2 PRK2 PRKCL2 | VTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQDs |
| Q16576 | S145 | Sugiyama | RBBP7 RBAP46 | EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE |
| Q16821 | S46 | EPSD | PPP1R3A PP1G | CEDEEVTFQPGFSPQPSRRGsDsSEDIYLDTPSSGTRRVsF |
| Q16821 | S48 | GPS6 | PPP1R3A PP1G | DEEVTFQPGFSPQPSRRGsDsSEDIYLDTPSSGTRRVsFAD |
| Q32P51 | S95 | Sugiyama | HNRNPA1L2 HNRNPA1L | TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| Q3KQU3 | S112 | Sugiyama | MAP7D1 KIAA1187 PARCC1 RPRC1 PP2464 | KsRGPtPPAMGPRDARPPRRssQPsPtAVPAsDsPPtKQEV |
| Q4V328 | S666 | Sugiyama | GRIPAP1 KIAA1167 | EELVLsEMNsPSRtQtGDsssIssFsYREILREKEssAVPA |
| Q58FF6 | S34 | Sugiyama | HSP90AB4P | IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN |
| Q58FF7 | S58 | Sugiyama | HSP90AB3P HSP90BC | IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q58FF7 | S63 | Sugiyama | HSP90AB3P HSP90BC | LISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERT |
| Q58FF8 | S58 | Sugiyama | HSP90AB2P HSP90BB | IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q58FF8 | S63 | Sugiyama | HSP90AB2P HSP90BB | LISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQEHT |
| Q5QNW6 | S37 | Sugiyama | H2BC18 HIST2H2BF | KAVTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| Q5T0N5 | S488 | Sugiyama | FNBP1L C1orf39 TOCA1 | NEAWLSEVEGKTGGRGDRRHssDINHLVtQGREsPEGsytD |
| Q5T5C0 | S692 | Sugiyama | STXBP5 LLGL3 | YGSNDPYRREPRSPRKsRQPsGAGLCDIsEGtVVPEDRCKS |
| Q658Y4 | S332 | Sugiyama | FAM91A1 | KNVPSVNRLKSTLDPQKMLLsWDGGESRsPVQEAssAtDtD |
| Q6GYQ0 | T798 | Sugiyama | RALGAPA1 GARNL1 KIAA0884 TULIP1 | tGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDMS |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | S54 | Sugiyama | TUBA3E | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6UX04 | S206 | Sugiyama | CWC27 SDCCAG10 UNQ438/PRO871 | KPEEEVKKLKPKGTKNFsLLsFGEEAEEEEEEVNRVSQSMK |
| Q6VEQ5 | S105 | Sugiyama | WASH2P FAM39B | AIKVFSSAKYPAPERLQEyGsIFTGAQDPGLQRRPRHRIQS |
| Q6VY07 | S534 | Sugiyama | PACS1 KIAA1175 | KERQLsKPLsERtNssDsERsPDLGHsTQIPRKVVYDQLNQ |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZN18 | S206 | Sugiyama | AEBP2 | DEGYGTGGGGSSATSGGRRGsLEMssDGEPLSRMDSEDSIS |
| Q70CQ2 | S3358 | Sugiyama | USP34 KIAA0570 KIAA0729 | AKERKTKDDEGAtPIKRRRVssDEEHtVDSCISDMKTETRE |
| Q70CQ2 | S3359 | Sugiyama | USP34 KIAA0570 KIAA0729 | KERKTKDDEGAtPIKRRRVssDEEHtVDSCISDMKTETREV |
| Q71U36 | S439 | Sugiyama | TUBA1A TUBA3 | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | S54 | Sugiyama | TUBA1A TUBA3 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T82 | Sugiyama | TUBA1A TUBA3 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q71UM5 | S78 | Sugiyama | RPS27L | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| Q7KZ85 | S125 | Sugiyama | SUPT6H KIAA0162 SPT6H | EENLGVKVKRGQKYRRVKKMsDDEDDDEEEYGKEEHEKEAI |
| Q7KZF4 | S150 | Sugiyama | SND1 TDRD11 | EGLAtRREGMRANNPEQNRLsECEEQAKAAKKGMWSEGNGS |
| Q7KZF4 | S473 | Sugiyama | SND1 TDRD11 | ALVSKGLATVIRYRQDDDQRssHyDELLAAEARAIKNGKGL |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q7Z4V5 | S369 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | EKERRRERADRGEAERGsGGssGDELREDDEPVKKRGRKGR |
| Q7Z4V5 | S395 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | REDDEPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKK |
| Q7Z4V5 | S396 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | EDDEPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKKP |
| Q7Z4V5 | S454 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | VRPEEKQQAKPVKVERTRKRsEGFsMDRKVEKKKEPSVEEK |
| Q86UF2 | S140 | Sugiyama | CTAGE6 CTAGE6P | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q86V48 | S957 | Sugiyama | LUZP1 | PTRIGKNVESTNSNAytQRsstDFsELEQPRSCLFEQGTRR |
| Q86V81 | S239 | Sugiyama | ALYREF ALY BEF THOC4 | tRGGARGRGRGAGRNSKQQLsAEELDAQLDAyNARMDts__ |
| Q86VQ1 | S223 | Sugiyama | GLCCI1 | QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR |
| Q8IVD9 | S193 | Sugiyama | NUDCD3 KIAA1068 | EQFQKNPDSYNGAVRENYTWsQDyTDLEVRVPVPKHVVKGK |
| Q8IX94 | S140 | Sugiyama | CTAGE4 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q8N122 | S719 | ELM|EPSD | RPTOR KIAA1303 RAPTOR | TTEGGSLtPVRDsPCtPRLRsVssYGNIRAVATARSLNKSL |
| Q8N122 | S721 | EPSD | RPTOR KIAA1303 RAPTOR | EGGSLtPVRDsPCtPRLRsVssYGNIRAVATARSLNKSLQN |
| Q8N122 | S722 | ELM | RPTOR KIAA1303 RAPTOR | GGSLtPVRDsPCtPRLRsVssYGNIRAVATARSLNKSLQNL |
| Q8N1F7 | S112 | Sugiyama | NUP93 KIAA0095 | PVKDTDIQGFLKNEKDNALLsAIEESRKRtFGMAEEYHRES |
| Q8N201 | S495 | Sugiyama | INTS1 KIAA1440 UNQ1821/PRO3434 | KFLAMVFQDLLTNKDDYLRAsRALLREIIKQTKHEINFQAF |
| Q8N684 | S166 | Sugiyama | CPSF7 | PGKVLNGEKVDVRPAtRQNLsQFEAQARKRECVRVPRGGIP |
| Q8N8S7 | S125 | Sugiyama | ENAH MENA | MHALEVLNSQETGPTLPRQNsQLPAQVQNGPSQEELEIQRR |
| Q8NBJ5 | S607 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | DRAKSQKMREQQALSREAKNsDVLQsPLDsAARDEL_____ |
| Q8NBJ7 | S256 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG |
| Q8NBJ7 | S283 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | GsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL__ |
| Q8NBS9 | S285 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | LLWFRDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETV |
| Q8NE71 | S105 | Sugiyama | ABCF1 ABC50 | KKDVDDDGEEKELMERLKKLsVPtsDEEDEVPAPKPRGGKK |
| Q8TAM6 | S280 | Sugiyama | ERMN KIAA1189 | TISYRKIRKGNTKQRIDEFEsMMHL________________ |
| Q8TBC4 | S417 | Sugiyama | UBA3 UBE1C | MKsPAItATLEGKNRTLYLQsVTsIEERTRPNLSKTLKELG |
| Q8TCD5 | S182 | Sugiyama | NT5C DNT1 UMPH2 | LFTCCHNRHLVLPPTRRRLLsWsDNWREILDSKRGAAQRE_ |
| Q8TD16 | S658 | Sugiyama | BICD2 KIAA0699 | IKHLQAAVDRTTELSRQRIAsQELGPAVDKDKEALMEEILK |
| Q8TD19 | S332 | Sugiyama | NEK9 KIAA1995 NEK8 NERCC | RREMEEKVTLLNAPTKRPRsstVtEAPIAVVTSRTSEVYVW |
| Q8TEW0 | S717 | Sugiyama | PARD3 PAR3 PAR3A | PGPELPIETALDDRERRIsHsLysGIEGLDEsPsRNAALsR |
| Q8WTS1 | S122 | Sugiyama | ABHD5 NCIE2 CGI-58 | RPVYAFDLLGFGRSSRPRFDsDAEEVENQFVESIEEWRCAL |
| Q8WVV9 | S86 | Sugiyama | HNRNPLL HNRPLL SRRF BLOCK24 | GGsHHKVsVsPVVHVRGLCEsVVEADLVEALEKFGTICYVM |
| Q92538 | S174 | Sugiyama | GBF1 KIAA0248 | NESVCEIMQSCFRICFEMRLsELLRKSAEHTLVDMVQLLFT |
| Q92570 | S376 | EPSD | NR4A3 CHN CSMF MINOR NOR1 TEC | GMVKEVVRTDsLKGRRGRLPsKPKsPLQQEPsQPsPPsPPI |
| Q92570 | S387 | EPSD | NR4A3 CHN CSMF MINOR NOR1 TEC | LKGRRGRLPsKPKsPLQQEPsQPsPPsPPICMMNALVRALT |
| Q92731 | S165 | GPS6 | ESR2 ESTRB NR3A2 | DAHFCAVCSDYASGYHYGVWsCEGCKAFFKRsIQGHNDYIC |
| Q92734 | S50 | Sugiyama | TFG | DITyDELVLMMQRVFRGKLLsNDEVTIKYKDEDGDLITIFD |
| Q92766 | S1167 | Sugiyama | RREB1 FINB | AGTSKKRGRKRGMRSRPRANsGGVDLDssGEFASIEKMLAT |
| Q92934 | S118 | GPS6|SIGNOR|iPTMNet|EPSD | BAD BBC6 BCL2L8 | RsAPPNLWAAQRYGRELRRMsDEFVDsFKKGLPRPKsAGtA |
| Q92934 | S153 | EPSD | BAD BBC6 BCL2L8 | KsAGtATQMRQSSSWTRVFQsWWDRNLGRGSSAPSQ_____ |
| Q92934 | S75 | SIGNOR|ELM|iPTMNet|EPSD | BAD BBC6 BCL2L8 | PTSSSHHGGAGAVEIRsRHssyPAGtEDDEGMGEEPsPFRG |
| Q92934 | S99 | ELM|EPSD | BAD BBC6 BCL2L8 | GtEDDEGMGEEPsPFRGRsRsAPPNLWAAQRYGRELRRMsD |
| Q93079 | S37 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| Q969G3 | S262 | Sugiyama | SMARCE1 BAF57 | EAELLQIEERHQEKKRKFLEsTDsFNNELKRLCGLKVEVDM |
| Q96C01 | S135 | Sugiyama | FAM136A | VDDHMHLIPTMTKKMKEALLsIGK_________________ |
| Q96CV9 | S526 | Sugiyama | OPTN FIP2 GLC1E HIP7 HYPL NRP | FEDGGRQsLMEMQsRHGARtsDsDQQAyLVQRGAEDRDWRQ |
| Q96E11 | S239 | Sugiyama | MRRF | LKKSKDTVsEDtIRLIEKQIsQMADDtVAELDRHLAVKTKE |
| Q96E11 | T245 | Sugiyama | MRRF | TVsEDtIRLIEKQIsQMADDtVAELDRHLAVKTKELLG___ |
| Q96G46 | T240 | Sugiyama | DUS3L | KREVRFERAEQALRRFsQGPtPAAAVPEGTAAEGAPRQENC |
| Q96JP5 | S85 | Sugiyama | ZFP91 ZNF757 FKSG11 | AAAVSRRRKAEYPRRRRssPsARPPDVPGQQPQAAKsPsPV |
| Q96KP4 | S58 | Sugiyama | CNDP2 CN2 CPGL HEL-S-13 PEPA | RGEIRRMMEVAAADVKQLGGsVELVDIGKQKLPDGSEIPLP |
| Q96RU3 | S497 | Sugiyama | FNBP1 FBP17 KIAA0554 | AWLAEVEGRLPARSEQARRQsGLyDSQNPPTVNNCAQDREs |
| Q99497 | S57 | Sugiyama | PARK7 | GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL |
| Q99543 | S275 | Sugiyama | DNAJC2 MPHOSPH11 MPP11 ZRF1 | RAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEKAKKEAEK |
| Q99613 | S39 | Sugiyama | EIF3C EIF3S8 | GEELVTKPVGGNyGKQPLLLsEDEEDTKRVVRSAKDKRFEE |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q99615 | S449 | Sugiyama | DNAJC7 TPR2 TTC2 | KEVGEAFTILSDPKKKtRYDsGQDLDEEGMNMGDFDPNNIF |
| Q99615 | T445 | Sugiyama | DNAJC7 TPR2 TTC2 | EKKFKEVGEAFTILSDPKKKtRYDsGQDLDEEGMNMGDFDP |
| Q99733 | S53 | Sugiyama | NAP1L4 NAP2 | QNPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQL |
| Q99877 | S37 | Sugiyama | H2BC15 H2BFD HIST1H2BN | KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| Q99879 | S37 | Sugiyama | H2BC14 H2BFE HIST1H2BM | KAINKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| Q99880 | S37 | Sugiyama | H2BC13 H2BFC HIST1H2BL | KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss |
| Q9BQ52 | S796 | Sugiyama | ELAC2 HPC2 | EEMEERREKRELRQVRAALLsRELAGGLEDGEPQQKRAHTE |
| Q9BQA1 | S185 | Sugiyama | WDR77 MEP50 WD45 HKMT1069 Nbla10071 | AHAAQVTCVAAsPHKDSVFLsCSEDNRILLWDTRCPKPASQ |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | S54 | Sugiyama | TUBA1C TUBA6 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T82 | Sugiyama | TUBA1C TUBA6 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q9BQG0 | S1186 | Sugiyama | MYBBP1A P160 | sKKRKKKGFLPETKKRKKRKsEDGtPAEDGtPAATGGsQPP |
| Q9BTC0 | S1456 | Sugiyama | DIDO1 C20orf158 DATF1 KIAA0333 | EAKVTVDDLPNRMCADVRRNsVERPAEPVAGAAtPsLVEQQ |
| Q9BTE6 | S174 | Sugiyama | AARSD1 | IEQSVNEKIRDRLPVNVRELsLDDPEVEQVsGRGLPDDHAG |
| Q9BVA1 | S75 | Sugiyama | TUBB2B | tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q9BWD1 | S226 | Sugiyama | ACAT2 ACTL | LVstRKGLIEVKtDEFPRHGsNIEAMSKLKPYFLTDGTGTV |
| Q9BX95 | T114 | Sugiyama | SGPP1 SPP1 | AAELGPAsPRRAGALRRNsLtGEEGQLARVSNWPLYCLFCF |
| Q9BXP5 | S675 | Sugiyama | SRRT ARS2 ASR2 | SHGEVLEWQKTFEEKLTPLLsVREsLSEEEAQKMGRKDPEQ |
| Q9BXP5 | S679 | Sugiyama | SRRT ARS2 ASR2 | VLEWQKTFEEKLTPLLsVREsLSEEEAQKMGRKDPEQEVEK |
| Q9BY44 | S526 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | sPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKLKA |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BZ23 | S140 | Sugiyama | PANK2 C20orf48 | LLLRMGGGRLGAPMERHGRAsAtsVssAGEQAAGDPEGRRQ |
| Q9BZ23 | S145 | Sugiyama | PANK2 C20orf48 | GGGRLGAPMERHGRAsAtsVssAGEQAAGDPEGRRQEPLRR |
| Q9BZ23 | T142 | Sugiyama | PANK2 C20orf48 | LRMGGGRLGAPMERHGRAsAtsVssAGEQAAGDPEGRRQEP |
| Q9BZI7 | S166 | Sugiyama | UPF3B RENT3B UPF3X | KRDTKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIE |
| Q9C0C2 | S1620 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | ADsDAHLFQDSTEPRAsRVPssDEEVVEEPQsRRTRMsLGT |
| Q9C0C2 | S882 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LQDQEFGKRDsLGtyssRDVsLGDWEFGKRDsLGAyAsQDA |
| Q9C0C2 | S920 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | QDANEQGQDLGKRDHHGRyssQDADEQDWEFQKRDVsLGTy |
| Q9GZT3 | S15 | Sugiyama | SLIRP C14orf156 DC23 DC50 PD04872 | ______MAASAARGAAALRRsINQPVAFVRRIPWTAASSQL |
| Q9GZZ9 | S44 | Sugiyama | UBA5 UBE1DC1 | sLQVPRSGDGGGGRVRIEKMssEVVDSNPysRLMALKRMGI |
| Q9H0A0 | S934 | Sugiyama | NAT10 ALP KIAA1709 | IEEQMVAAKDVVMEPTMKTLsDDLDEAAKEFQEKHKKEVGK |
| Q9H0B6 | S428 | Sugiyama | KLC2 | NKPIWMHAEEREESKDKRRDsAPyGEyGsWYKACKVDsPtV |
| Q9H0C5 | S273 | Sugiyama | BTBD1 C15orf1 NS5ATP8 | QRQQLPVTFGNKQKVLGKALsLIRFPLMTIEEFAAGPAQSG |
| Q9H0D6 | S678 | Sugiyama | XRN2 | LRAALEEVyPDLTPEEtRRNsLGGDVLFVGKHHPLHDFILE |
| Q9H2U2 | S313 | Sugiyama | PPA2 HSPC124 | VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG |
| Q9H3N1 | S226 | Sugiyama | TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 | LCPSKRRRPQPYPYPSKKLLsEsAQPLKKVEEEQEADEEDV |
| Q9H4A4 | S19 | Sugiyama | RNPEP APB | __MAsGEHsPGsGAARRPLHsAQAVDVAsAsNFRAFELLHL |
| Q9H6S0 | S1201 | Sugiyama | YTHDC2 | PMssEELPLASSWRSNNSRKssADtEFsDECTTAERVLMKs |
| Q9H6S0 | S1202 | Sugiyama | YTHDC2 | MssEELPLASSWRSNNSRKssADtEFsDECTTAERVLMKsP |
| Q9H788 | S315 | Sugiyama | SH2D4A PPP1R38 SH2A | LNSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRA |
| Q9H788 | S316 | Sugiyama | SH2D4A PPP1R38 SH2A | NSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRAG |
| Q9H7D7 | S121 | Sugiyama | WDR26 CDW2 MIP2 PRO0852 | ASSSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLN |
| Q9H7D7 | S123 | Sugiyama | WDR26 CDW2 MIP2 PRO0852 | SSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLNQT |
| Q9HA77 | T546 | Sugiyama | CARS2 OK/SW-cl.10 | CDTLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG__ |
| Q9HCN4 | S301 | Sugiyama | GPN1 MBDIN RPAP4 XAB1 HUSSY-23 | ANAESQQQREQLERLRKDMGsVALDAGtAKDsLsPVLHPsD |
| Q9NP61 | S367 | Sugiyama | ARFGAP3 ARFGAP1 | DsyFTSSSSYFDEPVELRsssFssWDDssDSyWKKETSKDT |
| Q9NPD8 | S184 | Sugiyama | UBE2T HSPC150 PIG50 | DNLPEAGDsRVHNstQKRKAsQLVGIEKKFHPDV_______ |
| Q9NQA3 | S87 | Sugiyama | WASH6P CXYorf1 FAM39A | AIKVFSSAKYPAPERLQEyGsIFTGAQDPGLQRRPRHRIQS |
| Q9NQC3 | S184 | Sugiyama | RTN4 KIAA0886 NOGO My043 SP1507 | PAPAAPPstPAAPKRRGssGsVDEtLFALPAASEPVIRSSA |
| Q9NQX3 | S262 | Sugiyama | GPHN GPH KIAA1385 | AKIPDSIISRGVQVLPRDTAsLsttPsEsPRAQAtsRLstA |
| Q9NTI5 | S1257 | Sugiyama | PDS5B APRIN AS3 KIAA0979 | LVQEQKPKGSQRSRKRGHtAsEsDEQQWPEEKRLKEDILEN |
| Q9NUU7 | T467 | Sugiyama | DDX19A DDX19L | SMNILNRIQEHFNKKIERLDtDDLDEIEKIAN_________ |
| Q9NWS0 | S173 | Sugiyama | PIH1D1 NOP17 | KYNLQLNPEWRMMKNRPFMGsIsQQNIRSEQRPRIQELGDL |
| Q9NY33 | S130 | Sugiyama | DPP3 | GDTKFVPNLPKEKLERVILGsEAAQQHPEEVRGLWQTCGEL |
| Q9NYB0 | S205 | GPS6 | TERF2IP DRIP5 RAP1 PP8000 | LKHLRGQEHKyLLGDAPVsPssQKLKRKAEEDPEAADsGEP |
| Q9NYF8 | Y322 | Sugiyama | BCLAF1 BTF KIAA0164 | AKtIAPQNAPRDEsRGRssFyPDGGDQETAKtGKFLKRFtD |
| Q9UBC2 | S377 | Sugiyama | EPS15L1 EPS15R | DMVPPsERGtPGPDssGsLGsGEFTGVKELDDISQEIAQLQ |
| Q9UBC2 | S672 | Sugiyama | EPS15L1 EPS15R | ttstDPFGGDPFKESDPFRGsAtDDFFKKQTKNDPFTSDPF |
| Q9UBC2 | T366 | Sugiyama | EPS15L1 EPS15R | KGIDPPQVLsPDMVPPsERGtPGPDssGsLGsGEFTGVKEL |
| Q9UBP6 | S27 | EPSD|Sugiyama | METTL1 C12orf1 | NVAGAEAPPPQKRYYRQRAHsNPMADHTLRYPVKPEEMDWS |
| Q9UGV2 | S331 | Sugiyama | NDRG3 | QGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQ |
| Q9UGV2 | T332 | Sugiyama | NDRG3 | GMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQs |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UK32 | S436 | Sugiyama | RPS6KA6 RSK4 | NGNAAQFGEVYELKEDIGVGsysVCKRCIHATTNMEFAVKI |
| Q9UK32 | S438 | Sugiyama | RPS6KA6 RSK4 | NAAQFGEVYELKEDIGVGsysVCKRCIHATTNMEFAVKIID |
| Q9UK32 | Y437 | Sugiyama | RPS6KA6 RSK4 | GNAAQFGEVYELKEDIGVGsysVCKRCIHATTNMEFAVKII |
| Q9UKV3 | S243 | Sugiyama | ACIN1 ACINUS KIAA0670 | KGERRSSRVRQARAAKLsEGsQPAEEEEDQEtPsRNLRVRA |
| Q9ULD2 | T1204 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | ENEELKARMDKHMAISRQLstEQAVLQESLEKESKVNKRLs |
| Q9UMR2 | T468 | Sugiyama | DDX19B DBP5 DDX19 TDBP | SMNILNRIQEHFNKKIERLDtDDLDEIEKIAN_________ |
| Q9UNF1 | S264 | Sugiyama | MAGED2 BCG1 | sLRsPKARRGKARRRAAKLQssQEPEAPPPRDVALLQGRAN |
| Q9UPN3 | S2769 | Sugiyama | MACF1 ABP620 ACF7 KIAA0465 KIAA0754 KIAA1251 | EAIEKRLISPELANMIQIDSsEFSDHRAQIEKQEGIEVCAL |
| Q9UPQ0 | S377 | Sugiyama | LIMCH1 KIAA1102 | LREEDDKWQDDLARWKSRRRsVsQDLIKKEEERKKMEKLLA |
| Q9UPQ0 | S875 | Sugiyama | LIMCH1 KIAA1102 | MNKIDLGNCQDEKQDRRWKKsFQGDDSDLLLKTRESDRLEE |
| Q9UQ35 | S1541 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | ssVDQKtVARtPLGQRsRsGssQELDVKPsAsPQERsEsDs |
| Q9UQ35 | S2692 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS |
| Q9Y2B0 | S115 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF |
| Q9Y2B0 | S55 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDELEWEIAQVDPKKTIQMGsFRINPDGsQsVVEVPyARsE |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2I7 | S307 | Sugiyama | PIKFYVE KIAA0981 PIP5K3 | TRLVSVQEDAGKsPARNRsAsItNLsLDRsGsPMVPSYEts |
| Q9Y2T7 | S137 | Sugiyama | YBX2 CSDA3 MSY2 | EDVFVHQtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEA |
| Q9Y2T7 | T143 | Sugiyama | YBX2 CSDA3 MSY2 | QtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEATNVTGP |
| Q9Y2U5 | S239 | Sugiyama | MAP3K2 MAPKKK2 MEKK2 | SLDSPLDGESYPKSRMPRAQsyPDNHQEFSDyDNPIFEKFG |
| Q9Y2X7 | S592 | Sugiyama | GIT1 | PLLsCsQEGsRHtsKLsRHGsGADsDyENtQSGDPLLGLEG |
| Q9Y3U8 | S91 | Sugiyama | RPL36 | KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______ |
| Q9Y450 | S49 | Sugiyama | HBS1L HBS1 KIAA1038 | DYCIsPsTAAQFIYSRRDKPsVEPVEEyDyEDLKEssNsVs |
| Q9Y534 | S58 | GPS6 | CSDC2 PIPPIN | GGVPPRDLPsPLPTKRTRTYsATARASAGPVFKGVCKQFSR |
| Q9Y5J9 | S50 | Sugiyama | TIMM8B DDP2 DDPL TIM8B | HHFMELCWDKCVEKPGNRLDsRTENCLsSCVDRFIDTTLAI |
| Q9Y5K3 | S260 | GPS6 | PCYT1B CCTB | YRFQNQVDKMKEKVKNVEERsKEFVNRVEEKSHDLIQKWEE |
| Q9Y5M8 | S257 | Sugiyama | SRPRB PSEC0230 | LPLKVEFLECSAKGGRGDVGsADIQDLEKWLAKIA______ |
| Q9Y5S9 | S56 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF |
| Q9Y5X1 | S116 | Sugiyama | SNX9 SH3PX1 SH3PXD3A | SNNHQVGSGNDPWSAWSASKsGNWESsEGWGAQPEGAGAQR |
| Q9Y618 | S67 | Sugiyama | NCOR2 CTG26 | RDYASHLSPGSIIQPQRRRPsLLsEFQPGNERSQELHLRPE |
| Q9Y618 | S70 | Sugiyama | NCOR2 CTG26 | ASHLSPGSIIQPQRRRPsLLsEFQPGNERSQELHLRPESHS |
| Q9Y6D5 | S1511 | Sugiyama | ARFGEF2 ARFGEP2 BIG2 | PVGMEEDssEKHLDVDLDRQsLssIDKNPsERGQsQLsNPT |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Chromatin modifying enzymes | R-HSA-3247509 | 1.482779e-09 | 8.829 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 2.563667e-09 | 8.591 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.299227e-07 | 6.886 | 1 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.517439e-07 | 6.819 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 3.243944e-07 | 6.489 | 1 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 3.677830e-07 | 6.434 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 5.347641e-07 | 6.272 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 5.055109e-07 | 6.296 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 7.438476e-07 | 6.129 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.004339e-06 | 5.998 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 1.423609e-06 | 5.847 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.913848e-06 | 5.718 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.000554e-06 | 5.699 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 3.880963e-06 | 5.411 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 4.495197e-06 | 5.347 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 5.062027e-06 | 5.296 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 5.089374e-06 | 5.293 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 5.704829e-06 | 5.244 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 6.126962e-06 | 5.213 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 5.969497e-06 | 5.224 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 5.819907e-06 | 5.235 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 7.181420e-06 | 5.144 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 8.922359e-06 | 5.050 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.016084e-05 | 4.993 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 1.178193e-05 | 4.929 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.178193e-05 | 4.929 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.381608e-05 | 4.860 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.624093e-05 | 4.789 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.685931e-05 | 4.773 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 2.144463e-05 | 4.669 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 2.225649e-05 | 4.653 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 2.103292e-05 | 4.677 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.292477e-05 | 4.640 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 2.391938e-05 | 4.621 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 2.605672e-05 | 4.584 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 2.605672e-05 | 4.584 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 3.176737e-05 | 4.498 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 3.409520e-05 | 4.467 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 3.783670e-05 | 4.422 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 4.350501e-05 | 4.361 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 4.934965e-05 | 4.307 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 5.541176e-05 | 4.256 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 5.903185e-05 | 4.229 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 5.751502e-05 | 4.240 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 6.101770e-05 | 4.215 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 6.154593e-05 | 4.211 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 7.124049e-05 | 4.147 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 7.323056e-05 | 4.135 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 7.619753e-05 | 4.118 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 8.552729e-05 | 4.068 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.484173e-05 | 4.023 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 9.508591e-05 | 4.022 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 9.403137e-05 | 4.027 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 1.217455e-04 | 3.915 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 1.778634e-04 | 3.750 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 2.013464e-04 | 3.696 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 2.156004e-04 | 3.666 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 2.244114e-04 | 3.649 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 2.749146e-04 | 3.561 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 2.651346e-04 | 3.577 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 2.749146e-04 | 3.561 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.759318e-04 | 3.559 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 3.224458e-04 | 3.492 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 3.200869e-04 | 3.495 | 0 | 0 |
| Depurination | R-HSA-73927 | 3.465501e-04 | 3.460 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 3.483292e-04 | 3.458 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 3.483292e-04 | 3.458 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 3.666846e-04 | 3.436 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 4.127988e-04 | 3.384 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 4.301635e-04 | 3.366 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 4.485844e-04 | 3.348 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 4.891161e-04 | 3.311 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 5.104586e-04 | 3.292 | 1 | 1 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 5.557675e-04 | 3.255 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 6.443120e-04 | 3.191 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 6.443120e-04 | 3.191 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 6.798851e-04 | 3.168 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 6.972992e-04 | 3.157 | 1 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 7.130346e-04 | 3.147 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 8.350342e-04 | 3.078 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 8.840253e-04 | 3.054 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 9.749802e-04 | 3.011 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.118590e-03 | 2.951 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.205860e-03 | 2.919 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.271296e-03 | 2.896 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.212208e-03 | 2.916 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 1.303352e-03 | 2.885 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 1.493765e-03 | 2.826 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 1.493765e-03 | 2.826 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 1.526282e-03 | 2.816 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.469720e-03 | 2.833 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.505693e-03 | 2.822 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.739773e-03 | 2.760 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.990807e-03 | 2.701 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.242270e-03 | 2.649 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 2.134895e-03 | 2.671 | 1 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 2.230301e-03 | 2.652 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 2.330140e-03 | 2.633 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 2.485073e-03 | 2.605 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 2.505199e-03 | 2.601 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 2.505199e-03 | 2.601 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 2.376804e-03 | 2.624 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 2.518493e-03 | 2.599 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 2.553467e-03 | 2.593 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 2.837857e-03 | 2.547 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 3.071031e-03 | 2.513 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 3.107566e-03 | 2.508 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 3.157872e-03 | 2.501 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 3.296220e-03 | 2.482 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 3.643448e-03 | 2.438 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 3.679026e-03 | 2.434 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 3.753750e-03 | 2.426 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 3.969625e-03 | 2.401 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 4.040589e-03 | 2.394 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 4.395809e-03 | 2.357 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 4.225138e-03 | 2.374 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 4.508077e-03 | 2.346 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 4.524117e-03 | 2.344 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 4.561931e-03 | 2.341 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 5.206078e-03 | 2.283 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 5.279624e-03 | 2.277 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 5.674589e-03 | 2.246 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 5.679766e-03 | 2.246 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 6.464328e-03 | 2.189 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 6.688510e-03 | 2.175 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 6.989346e-03 | 2.156 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 6.996536e-03 | 2.155 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 7.059591e-03 | 2.151 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 7.466018e-03 | 2.127 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 7.515263e-03 | 2.124 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 7.938135e-03 | 2.100 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 8.454751e-03 | 2.073 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 8.551317e-03 | 2.068 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 9.546864e-03 | 2.020 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 9.546864e-03 | 2.020 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 9.771649e-03 | 2.010 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 9.897366e-03 | 2.004 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.054175e-02 | 1.977 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.054175e-02 | 1.977 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.064391e-02 | 1.973 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.212870e-02 | 1.916 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.212870e-02 | 1.916 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.212870e-02 | 1.916 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.150718e-02 | 1.939 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 1.144855e-02 | 1.941 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.212870e-02 | 1.916 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.114885e-02 | 1.953 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.119508e-02 | 1.951 | 1 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 1.215292e-02 | 1.915 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.340933e-02 | 1.873 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.378006e-02 | 1.861 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.380884e-02 | 1.860 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 1.488777e-02 | 1.827 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.497749e-02 | 1.825 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.560448e-02 | 1.807 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 1.517570e-02 | 1.819 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 1.517570e-02 | 1.819 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 1.517570e-02 | 1.819 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.488777e-02 | 1.827 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.573185e-02 | 1.803 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.585864e-02 | 1.800 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.598122e-02 | 1.796 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 1.743979e-02 | 1.758 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.751475e-02 | 1.757 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.776690e-02 | 1.750 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 1.815992e-02 | 1.741 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 1.870450e-02 | 1.728 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.895862e-02 | 1.722 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 2.119567e-02 | 1.674 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 2.078864e-02 | 1.682 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 1.940422e-02 | 1.712 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.071538e-02 | 1.684 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 1.993454e-02 | 1.700 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.978827e-02 | 1.704 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 2.020523e-02 | 1.695 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 2.220038e-02 | 1.654 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 2.260844e-02 | 1.646 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.328725e-02 | 1.633 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.373218e-02 | 1.625 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 2.508100e-02 | 1.601 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 2.508100e-02 | 1.601 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 2.557820e-02 | 1.592 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 2.582041e-02 | 1.588 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 2.733376e-02 | 1.563 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 2.779290e-02 | 1.556 | 1 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.790656e-02 | 1.554 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 3.056657e-02 | 1.515 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 3.056657e-02 | 1.515 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 2.890837e-02 | 1.539 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 2.970822e-02 | 1.527 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 2.970822e-02 | 1.527 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 2.868149e-02 | 1.542 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 3.222199e-02 | 1.492 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.079373e-02 | 1.512 | 0 | 0 |
| Kinesins | R-HSA-983189 | 3.080282e-02 | 1.511 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.993310e-02 | 1.524 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 3.104410e-02 | 1.508 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 3.356159e-02 | 1.474 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 3.367473e-02 | 1.473 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 3.367473e-02 | 1.473 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 3.367473e-02 | 1.473 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 3.367473e-02 | 1.473 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 3.396811e-02 | 1.469 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 3.525257e-02 | 1.453 | 1 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 3.537694e-02 | 1.451 | 1 | 0 |
| TRP channels | R-HSA-3295583 | 3.574702e-02 | 1.447 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 3.649349e-02 | 1.438 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.908394e-02 | 1.408 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 3.977702e-02 | 1.400 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 4.075057e-02 | 1.390 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 4.075057e-02 | 1.390 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 4.382938e-02 | 1.358 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 4.560690e-02 | 1.341 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 4.556870e-02 | 1.341 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 4.524875e-02 | 1.344 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 4.130096e-02 | 1.384 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 4.130096e-02 | 1.384 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 4.075057e-02 | 1.390 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 4.057107e-02 | 1.392 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 4.130096e-02 | 1.384 | 1 | 1 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 4.075057e-02 | 1.390 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 4.396779e-02 | 1.357 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 4.678442e-02 | 1.330 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 4.821195e-02 | 1.317 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 4.821195e-02 | 1.317 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 4.919265e-02 | 1.308 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 5.016559e-02 | 1.300 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 5.016559e-02 | 1.300 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 5.016559e-02 | 1.300 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 5.121948e-02 | 1.291 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 5.284779e-02 | 1.277 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 5.284779e-02 | 1.277 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 5.324184e-02 | 1.274 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 5.418234e-02 | 1.266 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 5.418234e-02 | 1.266 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 5.418234e-02 | 1.266 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 5.418234e-02 | 1.266 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 5.445271e-02 | 1.264 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 5.472991e-02 | 1.262 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 5.527740e-02 | 1.257 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 6.758937e-02 | 1.170 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 6.095229e-02 | 1.215 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 6.095229e-02 | 1.215 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 6.377735e-02 | 1.195 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 6.723420e-02 | 1.172 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 6.758937e-02 | 1.170 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 6.723420e-02 | 1.172 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 6.379357e-02 | 1.195 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 6.668179e-02 | 1.176 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 6.372753e-02 | 1.196 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 6.372753e-02 | 1.196 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 6.439927e-02 | 1.191 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 6.694139e-02 | 1.174 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 6.833968e-02 | 1.165 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 6.960692e-02 | 1.157 | 1 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 7.073802e-02 | 1.150 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 7.291946e-02 | 1.137 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 7.291946e-02 | 1.137 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 7.294928e-02 | 1.137 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 7.417399e-02 | 1.130 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 7.417399e-02 | 1.130 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 7.534051e-02 | 1.123 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 7.753774e-02 | 1.110 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 7.766270e-02 | 1.110 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 7.816014e-02 | 1.107 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 7.915779e-02 | 1.102 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 7.954698e-02 | 1.099 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 7.954698e-02 | 1.099 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 7.954698e-02 | 1.099 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 7.954698e-02 | 1.099 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 8.554940e-02 | 1.068 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 8.613719e-02 | 1.065 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 8.863171e-02 | 1.052 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 8.863171e-02 | 1.052 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 9.190236e-02 | 1.037 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 9.218319e-02 | 1.035 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 9.218319e-02 | 1.035 | 0 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 1.095862e-01 | 0.960 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 1.095862e-01 | 0.960 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 1.095862e-01 | 0.960 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 1.095862e-01 | 0.960 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.095862e-01 | 0.960 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 1.095862e-01 | 0.960 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 1.095862e-01 | 0.960 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 1.095862e-01 | 0.960 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 1.095862e-01 | 0.960 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 1.095862e-01 | 0.960 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 1.120391e-01 | 0.951 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.120391e-01 | 0.951 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 9.932428e-02 | 1.003 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 9.782830e-02 | 1.010 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 9.352622e-02 | 1.029 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 9.853548e-02 | 1.006 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 1.004824e-01 | 0.998 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 9.352622e-02 | 1.029 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 1.033154e-01 | 0.986 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.109883e-01 | 0.955 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 9.904679e-02 | 1.004 | 1 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 9.932428e-02 | 1.003 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 9.352622e-02 | 1.029 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 9.782830e-02 | 1.010 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 1.109883e-01 | 0.955 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 9.558344e-02 | 1.020 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 1.152115e-01 | 0.939 | 1 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.071689e-01 | 0.684 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.071689e-01 | 0.684 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.071689e-01 | 0.684 | 0 | 0 |
| Impaired BRCA2 translocation to the nucleus | R-HSA-9709275 | 2.071689e-01 | 0.684 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.071689e-01 | 0.684 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.071689e-01 | 0.684 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.071689e-01 | 0.684 | 0 | 0 |
| Impaired BRCA2 binding to SEM1 (DSS1) | R-HSA-9763198 | 2.071689e-01 | 0.684 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.071689e-01 | 0.684 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.545321e-01 | 0.811 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.545321e-01 | 0.811 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 1.545321e-01 | 0.811 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.545321e-01 | 0.811 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 1.545321e-01 | 0.811 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 1.545321e-01 | 0.811 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 1.545321e-01 | 0.811 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 1.545321e-01 | 0.811 | 0 | 0 |
| PI and PC transport between ER and Golgi membranes | R-HSA-1483196 | 2.940624e-01 | 0.532 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 2.940624e-01 | 0.532 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 2.940624e-01 | 0.532 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 2.940624e-01 | 0.532 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.940624e-01 | 0.532 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.940624e-01 | 0.532 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.940624e-01 | 0.532 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 2.940624e-01 | 0.532 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.940624e-01 | 0.532 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.940624e-01 | 0.532 | 0 | 0 |
| MyD88 deficiency (TLR5) | R-HSA-5602680 | 2.940624e-01 | 0.532 | 0 | 0 |
| Intestinal infectious diseases | R-HSA-8942233 | 2.940624e-01 | 0.532 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5619101 | 2.940624e-01 | 0.532 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 2.940624e-01 | 0.532 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 2.940624e-01 | 0.532 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 2.940624e-01 | 0.532 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.940624e-01 | 0.532 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5660686 | 2.940624e-01 | 0.532 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 2.940624e-01 | 0.532 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.940624e-01 | 0.532 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 2.940624e-01 | 0.532 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 1.956779e-01 | 0.708 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.956779e-01 | 0.708 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.956779e-01 | 0.708 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.179510e-01 | 0.928 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 1.179510e-01 | 0.928 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.179510e-01 | 0.928 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.179510e-01 | 0.928 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.179510e-01 | 0.928 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.179510e-01 | 0.928 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.647066e-01 | 0.783 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 1.647066e-01 | 0.783 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.647066e-01 | 0.783 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 2.379627e-01 | 0.623 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 2.379627e-01 | 0.623 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.379627e-01 | 0.623 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 2.379627e-01 | 0.623 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 2.379627e-01 | 0.623 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 2.379627e-01 | 0.623 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 2.379627e-01 | 0.623 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 3.714370e-01 | 0.430 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 3.714370e-01 | 0.430 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 3.714370e-01 | 0.430 | 0 | 0 |
| HHAT G278V doesn't palmitoylate Hh-Np | R-HSA-5658034 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 3.714370e-01 | 0.430 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 3.714370e-01 | 0.430 | 0 | 0 |
| TWIK related potassium channel (TREK) | R-HSA-1299503 | 3.714370e-01 | 0.430 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 3.714370e-01 | 0.430 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 3.714370e-01 | 0.430 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.379608e-01 | 0.860 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 1.933278e-01 | 0.714 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 1.933278e-01 | 0.714 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 1.933278e-01 | 0.714 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.806434e-01 | 0.552 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 2.806434e-01 | 0.552 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 2.806434e-01 | 0.552 | 1 | 1 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors | R-HSA-629587 | 2.806434e-01 | 0.552 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.324477e-01 | 0.878 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 1.324477e-01 | 0.878 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.230573e-01 | 0.652 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 2.230573e-01 | 0.652 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 2.230573e-01 | 0.652 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 2.230573e-01 | 0.652 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 2.230573e-01 | 0.652 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 2.230573e-01 | 0.652 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.815867e-01 | 0.741 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.815867e-01 | 0.741 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 1.170379e-01 | 0.932 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 1.683493e-01 | 0.774 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 1.683493e-01 | 0.774 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 2.049123e-01 | 0.688 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 2.049123e-01 | 0.688 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 2.535996e-01 | 0.596 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 2.535996e-01 | 0.596 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 3.231255e-01 | 0.491 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 3.231255e-01 | 0.491 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 3.231255e-01 | 0.491 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 3.231255e-01 | 0.491 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 3.231255e-01 | 0.491 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 3.231255e-01 | 0.491 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 3.231255e-01 | 0.491 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 3.231255e-01 | 0.491 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 3.231255e-01 | 0.491 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 4.403349e-01 | 0.356 | 0 | 0 |
| PLC-gamma1 signalling | R-HSA-167021 | 4.403349e-01 | 0.356 | 0 | 0 |
| Activated NTRK3 signals through PLCG1 | R-HSA-9034793 | 4.403349e-01 | 0.356 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 4.403349e-01 | 0.356 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of other transcription factors | R-HSA-8866906 | 4.403349e-01 | 0.356 | 0 | 0 |
| Defective GCLC causes HAGGSD | R-HSA-5578999 | 4.403349e-01 | 0.356 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.403349e-01 | 0.356 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 4.403349e-01 | 0.356 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 4.403349e-01 | 0.356 | 0 | 0 |
| Defective ABCA1 causes TGD | R-HSA-5682113 | 4.403349e-01 | 0.356 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.403349e-01 | 0.356 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.554237e-01 | 0.808 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 1.875852e-01 | 0.727 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 2.290465e-01 | 0.640 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 2.290465e-01 | 0.640 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.433124e-01 | 0.844 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 1.717460e-01 | 0.765 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 2.846790e-01 | 0.546 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 1.574210e-01 | 0.803 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 1.887401e-01 | 0.724 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.887401e-01 | 0.724 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.887401e-01 | 0.724 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 3.649404e-01 | 0.438 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 3.649404e-01 | 0.438 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 3.649404e-01 | 0.438 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 3.649404e-01 | 0.438 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 3.649404e-01 | 0.438 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 3.649404e-01 | 0.438 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 3.649404e-01 | 0.438 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.721346e-01 | 0.764 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.063501e-01 | 0.685 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.063501e-01 | 0.685 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 3.160420e-01 | 0.500 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 1.708095e-01 | 0.767 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 2.791440e-01 | 0.554 | 0 | 0 |
| PKA activation | R-HSA-163615 | 2.791440e-01 | 0.554 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 2.791440e-01 | 0.554 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 2.245168e-01 | 0.649 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.245168e-01 | 0.649 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 2.032298e-01 | 0.692 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 2.032298e-01 | 0.692 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 2.032298e-01 | 0.692 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 1.847270e-01 | 0.733 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 1.847270e-01 | 0.733 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 1.847270e-01 | 0.733 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 2.431793e-01 | 0.614 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 2.431793e-01 | 0.614 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.710622e-01 | 0.567 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.710622e-01 | 0.567 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 3.048178e-01 | 0.516 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.048178e-01 | 0.516 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 3.474587e-01 | 0.459 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 4.057241e-01 | 0.392 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 4.057241e-01 | 0.392 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 4.057241e-01 | 0.392 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 4.057241e-01 | 0.392 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 4.057241e-01 | 0.392 | 0 | 0 |
| Activated NTRK2 signals through PLCG1 | R-HSA-9026527 | 5.016844e-01 | 0.300 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 5.016844e-01 | 0.300 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 5.016844e-01 | 0.300 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 5.016844e-01 | 0.300 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.731524e-01 | 0.762 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.548052e-01 | 0.810 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 3.307247e-01 | 0.481 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 3.307247e-01 | 0.481 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 3.307247e-01 | 0.481 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 3.307247e-01 | 0.481 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 3.787238e-01 | 0.422 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 3.787238e-01 | 0.422 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 3.787238e-01 | 0.422 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 3.787238e-01 | 0.422 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.189687e-01 | 0.925 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.744973e-01 | 0.758 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 2.082879e-01 | 0.681 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 2.082879e-01 | 0.681 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.015127e-01 | 0.521 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 4.452006e-01 | 0.351 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 4.452006e-01 | 0.351 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 2.510292e-01 | 0.600 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.215284e-01 | 0.493 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 4.096561e-01 | 0.388 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 4.096561e-01 | 0.388 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 4.096561e-01 | 0.388 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.557386e-01 | 0.592 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.557386e-01 | 0.592 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.461550e-01 | 0.609 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.028581e-01 | 0.693 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 3.827327e-01 | 0.417 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 3.606466e-01 | 0.443 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 3.606466e-01 | 0.443 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 3.606466e-01 | 0.443 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 2.726813e-01 | 0.564 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 4.086027e-01 | 0.389 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 4.086027e-01 | 0.389 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 4.400983e-01 | 0.356 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 4.400983e-01 | 0.356 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 4.400983e-01 | 0.356 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 5.563121e-01 | 0.255 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 5.563121e-01 | 0.255 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 5.563121e-01 | 0.255 | 0 | 0 |
| Defective SLC1A3 causes episodic ataxia 6 (EA6) | R-HSA-5619062 | 5.563121e-01 | 0.255 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 5.563121e-01 | 0.255 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 5.563121e-01 | 0.255 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 5.563121e-01 | 0.255 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 3.008249e-01 | 0.522 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 4.060008e-01 | 0.391 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 4.060008e-01 | 0.391 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 4.060008e-01 | 0.391 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 4.342447e-01 | 0.362 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.783505e-01 | 0.555 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.783505e-01 | 0.555 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 4.699153e-01 | 0.328 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 4.285480e-01 | 0.368 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 4.285480e-01 | 0.368 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 4.595668e-01 | 0.338 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 5.194787e-01 | 0.284 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 5.194787e-01 | 0.284 | 0 | 0 |
| Presynaptic nicotinic acetylcholine receptors | R-HSA-622323 | 5.194787e-01 | 0.284 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 5.194787e-01 | 0.284 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 5.194787e-01 | 0.284 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 3.657962e-01 | 0.437 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 3.789931e-01 | 0.421 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 4.844867e-01 | 0.315 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 4.730487e-01 | 0.325 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 4.634795e-01 | 0.334 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 4.218864e-01 | 0.375 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 4.218864e-01 | 0.375 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 5.272392e-01 | 0.278 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 5.272392e-01 | 0.278 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 5.540437e-01 | 0.256 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 5.540437e-01 | 0.256 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 5.540437e-01 | 0.256 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 5.540437e-01 | 0.256 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 5.540437e-01 | 0.256 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 5.540437e-01 | 0.256 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.516349e-01 | 0.345 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 4.587498e-01 | 0.338 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 5.030421e-01 | 0.298 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 5.374655e-01 | 0.270 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 5.234551e-01 | 0.281 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 5.581254e-01 | 0.253 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 5.624394e-01 | 0.250 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 5.600354e-01 | 0.252 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 5.788251e-01 | 0.237 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 5.786286e-01 | 0.238 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.109365e-01 | 0.676 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 5.581254e-01 | 0.253 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.788251e-01 | 0.237 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 4.699153e-01 | 0.328 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 4.699153e-01 | 0.328 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 1.499430e-01 | 0.824 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.991118e-01 | 0.701 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 4.180502e-01 | 0.379 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 2.299767e-01 | 0.638 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.060008e-01 | 0.391 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 3.807217e-01 | 0.419 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.229433e-01 | 0.910 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 5.783150e-01 | 0.238 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 2.150799e-01 | 0.667 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 3.606466e-01 | 0.443 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 5.545766e-01 | 0.256 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.434446e-01 | 0.843 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.179510e-01 | 0.928 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.812533e-01 | 0.742 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 3.649404e-01 | 0.438 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 4.140775e-01 | 0.383 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.731524e-01 | 0.762 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 4.410765e-01 | 0.355 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 4.410765e-01 | 0.355 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 2.035569e-01 | 0.691 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 3.280390e-01 | 0.484 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 2.150799e-01 | 0.667 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 1.956779e-01 | 0.708 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 5.545766e-01 | 0.256 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 1.379608e-01 | 0.860 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 3.631501e-01 | 0.440 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.647066e-01 | 0.783 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 1.933278e-01 | 0.714 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 1.933278e-01 | 0.714 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 1.554237e-01 | 0.808 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.321338e-01 | 0.879 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 4.634795e-01 | 0.334 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 2.032298e-01 | 0.692 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 1.561068e-01 | 0.807 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 4.989936e-01 | 0.302 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 2.817406e-01 | 0.550 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 1.647066e-01 | 0.783 | 0 | 0 |
| Formation of lateral plate mesoderm | R-HSA-9758920 | 2.379627e-01 | 0.623 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.933278e-01 | 0.714 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.231255e-01 | 0.491 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 4.452006e-01 | 0.351 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 4.452006e-01 | 0.351 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.086027e-01 | 0.389 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 4.516349e-01 | 0.345 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 4.268796e-01 | 0.370 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.281012e-01 | 0.484 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 5.089316e-01 | 0.293 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 5.163712e-01 | 0.287 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 1.887401e-01 | 0.724 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 3.299883e-01 | 0.482 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 4.917846e-01 | 0.308 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.411548e-01 | 0.850 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 3.215284e-01 | 0.493 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 5.328381e-01 | 0.273 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 5.438331e-01 | 0.265 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 1.545321e-01 | 0.811 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.545321e-01 | 0.811 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 1.375039e-01 | 0.862 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 1.647066e-01 | 0.783 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 1.592202e-01 | 0.798 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 3.649404e-01 | 0.438 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 3.015127e-01 | 0.521 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 3.833430e-01 | 0.416 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 5.563121e-01 | 0.255 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 4.342447e-01 | 0.362 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 3.736836e-01 | 0.427 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 4.086426e-01 | 0.389 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 4.196038e-01 | 0.377 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.694108e-01 | 0.432 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 4.819937e-01 | 0.317 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 4.912540e-01 | 0.309 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 3.015127e-01 | 0.521 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.516571e-01 | 0.258 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 5.415150e-01 | 0.266 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.673688e-01 | 0.573 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 4.400983e-01 | 0.356 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 3.134321e-01 | 0.504 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 3.154475e-01 | 0.501 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 5.438331e-01 | 0.265 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 1.933278e-01 | 0.714 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 2.195308e-01 | 0.659 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.944663e-01 | 0.711 | 1 | 1 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 5.540437e-01 | 0.256 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 5.540437e-01 | 0.256 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 3.067949e-01 | 0.513 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 5.089316e-01 | 0.293 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 2.709222e-01 | 0.567 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 4.452006e-01 | 0.351 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 4.231491e-01 | 0.374 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 3.005103e-01 | 0.522 | 1 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 5.786286e-01 | 0.238 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 2.817406e-01 | 0.550 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.049123e-01 | 0.688 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.275258e-01 | 0.485 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 3.959001e-01 | 0.402 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.647066e-01 | 0.783 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 1.379608e-01 | 0.860 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 3.231255e-01 | 0.491 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 3.231255e-01 | 0.491 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 1.298417e-01 | 0.887 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 3.649404e-01 | 0.438 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 3.048178e-01 | 0.516 | 1 | 1 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 3.474587e-01 | 0.459 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 3.015127e-01 | 0.521 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 4.096561e-01 | 0.388 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 4.096561e-01 | 0.388 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 2.494588e-01 | 0.603 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 4.831665e-01 | 0.316 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 4.699153e-01 | 0.328 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 5.194787e-01 | 0.284 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 4.819937e-01 | 0.317 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 5.321945e-01 | 0.274 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 5.321945e-01 | 0.274 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 5.321945e-01 | 0.274 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 5.321945e-01 | 0.274 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 3.620826e-01 | 0.441 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 4.150075e-01 | 0.382 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.758122e-01 | 0.425 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 4.572255e-01 | 0.340 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 1.867766e-01 | 0.729 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 5.656592e-01 | 0.247 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.721346e-01 | 0.764 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 4.060008e-01 | 0.391 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 4.948835e-01 | 0.305 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 4.983259e-01 | 0.302 | 1 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 4.917846e-01 | 0.308 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 4.917846e-01 | 0.308 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 4.983259e-01 | 0.302 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 4.983259e-01 | 0.302 | 1 | 0 |
| Downstream signal transduction | R-HSA-186763 | 1.433124e-01 | 0.844 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 3.474587e-01 | 0.459 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 2.098993e-01 | 0.678 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 5.328381e-01 | 0.273 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 3.412204e-01 | 0.467 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 1.815867e-01 | 0.741 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 1.721346e-01 | 0.764 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 5.016844e-01 | 0.300 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 5.730532e-01 | 0.242 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 2.195308e-01 | 0.659 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.329556e-01 | 0.478 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.327991e-01 | 0.877 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 5.602565e-01 | 0.252 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 5.602565e-01 | 0.252 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 5.199185e-01 | 0.284 | 1 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.115695e-01 | 0.675 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.222128e-01 | 0.913 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 4.732954e-01 | 0.325 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 5.679432e-01 | 0.246 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 4.502093e-01 | 0.347 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 4.169069e-01 | 0.380 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 2.245168e-01 | 0.649 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 4.400983e-01 | 0.356 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 3.014025e-01 | 0.521 | 1 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.625072e-01 | 0.581 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 4.634795e-01 | 0.334 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 5.030421e-01 | 0.298 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 5.528684e-01 | 0.257 | 0 | 0 |
| PTK6 Activates STAT3 | R-HSA-8849474 | 5.563121e-01 | 0.255 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 3.609274e-01 | 0.443 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 5.475799e-01 | 0.262 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 5.626583e-01 | 0.250 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 2.388310e-01 | 0.622 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.867766e-01 | 0.729 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 4.595668e-01 | 0.338 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 5.106140e-01 | 0.292 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 2.804529e-01 | 0.552 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.015127e-01 | 0.521 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.260861e-01 | 0.899 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 4.529399e-01 | 0.344 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 2.031741e-01 | 0.692 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 2.970939e-01 | 0.527 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 4.509180e-01 | 0.346 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 1.962507e-01 | 0.707 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 1.375039e-01 | 0.862 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 1.647066e-01 | 0.783 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 2.230573e-01 | 0.652 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 2.230573e-01 | 0.652 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 2.049123e-01 | 0.688 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 2.535996e-01 | 0.596 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 2.535996e-01 | 0.596 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 4.403349e-01 | 0.356 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 4.403349e-01 | 0.356 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 2.846790e-01 | 0.546 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 3.649404e-01 | 0.438 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 3.160420e-01 | 0.500 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 2.791440e-01 | 0.554 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 2.245168e-01 | 0.649 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 5.016844e-01 | 0.300 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 2.338458e-01 | 0.631 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 4.400983e-01 | 0.356 | 0 | 0 |
| Trafficking of myristoylated proteins to the cilium | R-HSA-5624138 | 5.563121e-01 | 0.255 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 5.563121e-01 | 0.255 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 5.194787e-01 | 0.284 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 4.582634e-01 | 0.339 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 4.169069e-01 | 0.380 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 5.098143e-01 | 0.293 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 5.561513e-01 | 0.255 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 5.783150e-01 | 0.238 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 5.783150e-01 | 0.238 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 3.605191e-01 | 0.443 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 2.082879e-01 | 0.681 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 1.206528e-01 | 0.918 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.701114e-01 | 0.769 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 3.933280e-01 | 0.405 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 3.827327e-01 | 0.417 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 4.180502e-01 | 0.379 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 5.581254e-01 | 0.253 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 2.264178e-01 | 0.645 | 1 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 2.710622e-01 | 0.567 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 4.806009e-01 | 0.318 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 1.721346e-01 | 0.764 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 4.948835e-01 | 0.305 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 5.201412e-01 | 0.284 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 4.634795e-01 | 0.334 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 2.077696e-01 | 0.682 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 5.485281e-01 | 0.261 | 1 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 2.587324e-01 | 0.587 | 1 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.913115e-01 | 0.718 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.933278e-01 | 0.714 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 4.057241e-01 | 0.392 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 4.452006e-01 | 0.351 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 3.827327e-01 | 0.417 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 4.400983e-01 | 0.356 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 5.561513e-01 | 0.255 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 5.788251e-01 | 0.237 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 3.429057e-01 | 0.465 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 1.554237e-01 | 0.808 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 4.983259e-01 | 0.302 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.991118e-01 | 0.701 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.791440e-01 | 0.554 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 2.291602e-01 | 0.640 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 5.073099e-01 | 0.295 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 2.139337e-01 | 0.670 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.261048e-01 | 0.899 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.744973e-01 | 0.758 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 2.494588e-01 | 0.603 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 2.204272e-01 | 0.657 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 1.647066e-01 | 0.783 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 2.379627e-01 | 0.623 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 1.815867e-01 | 0.741 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 4.057241e-01 | 0.392 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 4.057241e-01 | 0.392 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 3.307247e-01 | 0.481 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 4.086027e-01 | 0.389 | 0 | 0 |
| LGI-ADAM interactions | R-HSA-5682910 | 4.831665e-01 | 0.316 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 5.563121e-01 | 0.255 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 4.342447e-01 | 0.362 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 4.948835e-01 | 0.305 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 1.721606e-01 | 0.764 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 5.602565e-01 | 0.252 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 5.321945e-01 | 0.274 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 4.057241e-01 | 0.392 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 5.089316e-01 | 0.293 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 5.540437e-01 | 0.256 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 4.956645e-01 | 0.305 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 5.788251e-01 | 0.237 | 1 | 0 |
| HCMV Late Events | R-HSA-9610379 | 5.577998e-01 | 0.254 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 1.324477e-01 | 0.878 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 5.485281e-01 | 0.261 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 5.646249e-01 | 0.248 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 4.699153e-01 | 0.328 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 4.989034e-01 | 0.302 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 2.934237e-01 | 0.533 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 3.126140e-01 | 0.505 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 4.218864e-01 | 0.375 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 5.051029e-01 | 0.297 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 2.940624e-01 | 0.532 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 1.956779e-01 | 0.708 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 3.714370e-01 | 0.430 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 1.933278e-01 | 0.714 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 2.230573e-01 | 0.652 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 4.057241e-01 | 0.392 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 5.016844e-01 | 0.300 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 3.015127e-01 | 0.521 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 4.452006e-01 | 0.351 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 4.096561e-01 | 0.388 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 3.827327e-01 | 0.417 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 4.400983e-01 | 0.356 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 4.400983e-01 | 0.356 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 4.831665e-01 | 0.316 | 0 | 0 |
| Biosynthesis of DPAn-3-derived 13-series resolvins | R-HSA-9026403 | 5.563121e-01 | 0.255 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 2.625072e-01 | 0.581 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 5.561513e-01 | 0.255 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 1.636862e-01 | 0.786 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.273305e-01 | 0.643 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 1.499430e-01 | 0.824 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.580177e-01 | 0.588 | 1 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 4.292124e-01 | 0.367 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 4.649425e-01 | 0.333 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 3.160420e-01 | 0.500 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 5.254309e-01 | 0.279 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.273305e-01 | 0.643 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 5.328381e-01 | 0.273 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.298417e-01 | 0.887 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 4.831665e-01 | 0.316 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 2.772541e-01 | 0.557 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 3.889610e-01 | 0.410 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 5.163712e-01 | 0.287 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 5.272392e-01 | 0.278 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 3.787238e-01 | 0.422 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 3.787238e-01 | 0.422 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 4.366566e-01 | 0.360 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 2.887287e-01 | 0.540 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 3.768849e-01 | 0.424 | 1 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.730487e-01 | 0.325 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 1.956779e-01 | 0.708 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 1.375039e-01 | 0.862 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 3.714370e-01 | 0.430 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 3.231255e-01 | 0.491 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 3.231255e-01 | 0.491 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 4.403349e-01 | 0.356 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 3.649404e-01 | 0.438 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 5.563121e-01 | 0.255 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 4.844867e-01 | 0.315 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.649425e-01 | 0.333 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.554237e-01 | 0.808 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 3.154475e-01 | 0.501 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 5.032580e-01 | 0.298 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 5.556461e-01 | 0.255 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 5.540437e-01 | 0.256 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.633612e-01 | 0.579 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 4.060008e-01 | 0.391 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 2.379627e-01 | 0.623 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.379627e-01 | 0.623 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.815867e-01 | 0.741 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 4.403349e-01 | 0.356 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 3.160420e-01 | 0.500 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 5.563121e-01 | 0.255 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 1.466945e-01 | 0.834 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.791440e-01 | 0.554 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 5.540437e-01 | 0.256 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 2.332576e-01 | 0.632 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 5.540437e-01 | 0.256 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 3.855697e-01 | 0.414 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 4.452006e-01 | 0.351 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 5.573837e-01 | 0.254 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 5.794072e-01 | 0.237 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 5.809466e-01 | 0.236 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 5.809466e-01 | 0.236 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 5.809466e-01 | 0.236 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 5.809466e-01 | 0.236 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 5.809466e-01 | 0.236 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 5.809466e-01 | 0.236 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 5.868080e-01 | 0.232 | 0 | 0 |
| Acetylcholine binding and downstream events | R-HSA-181431 | 5.868080e-01 | 0.232 | 0 | 0 |
| Postsynaptic nicotinic acetylcholine receptors | R-HSA-622327 | 5.868080e-01 | 0.232 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 5.868080e-01 | 0.232 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 5.868080e-01 | 0.232 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 5.868080e-01 | 0.232 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 5.868080e-01 | 0.232 | 0 | 0 |
| rRNA modification in the mitochondrion | R-HSA-6793080 | 5.868080e-01 | 0.232 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 5.868080e-01 | 0.232 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 5.879780e-01 | 0.231 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.960307e-01 | 0.225 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 5.960307e-01 | 0.225 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 5.960506e-01 | 0.225 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 5.963860e-01 | 0.224 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 5.966059e-01 | 0.224 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 5.980032e-01 | 0.223 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 5.995815e-01 | 0.222 | 1 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 6.008215e-01 | 0.221 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 6.008215e-01 | 0.221 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 6.008215e-01 | 0.221 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 6.017325e-01 | 0.221 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.049541e-01 | 0.218 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.049541e-01 | 0.218 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.049541e-01 | 0.218 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.049541e-01 | 0.218 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.049541e-01 | 0.218 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 6.049541e-01 | 0.218 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 6.049541e-01 | 0.218 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 6.049541e-01 | 0.218 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 6.049541e-01 | 0.218 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 6.049541e-01 | 0.218 | 0 | 0 |
| NGF-independant TRKA activation | R-HSA-187024 | 6.049541e-01 | 0.218 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 6.049541e-01 | 0.218 | 0 | 0 |
| Formation of the Editosome | R-HSA-75094 | 6.049541e-01 | 0.218 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 6.049541e-01 | 0.218 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 6.049541e-01 | 0.218 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 6.049541e-01 | 0.218 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.049541e-01 | 0.218 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 6.049541e-01 | 0.218 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.049541e-01 | 0.218 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 6.049541e-01 | 0.218 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 6.049541e-01 | 0.218 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.049541e-01 | 0.218 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 6.049541e-01 | 0.218 | 0 | 0 |
| Acetylcholine inhibits contraction of outer hair cells | R-HSA-9667769 | 6.049541e-01 | 0.218 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 6.049541e-01 | 0.218 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 6.049541e-01 | 0.218 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 6.049541e-01 | 0.218 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 6.063050e-01 | 0.217 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 6.063050e-01 | 0.217 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 6.063050e-01 | 0.217 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 6.116024e-01 | 0.214 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 6.123508e-01 | 0.213 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 6.171634e-01 | 0.210 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 6.177512e-01 | 0.209 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 6.177512e-01 | 0.209 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 6.177512e-01 | 0.209 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 6.177512e-01 | 0.209 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 6.177512e-01 | 0.209 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 6.183021e-01 | 0.209 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 6.221096e-01 | 0.206 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 6.234513e-01 | 0.205 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 6.249290e-01 | 0.204 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 6.306211e-01 | 0.200 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 6.306211e-01 | 0.200 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 6.306211e-01 | 0.200 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 6.306211e-01 | 0.200 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 6.312895e-01 | 0.200 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 6.349597e-01 | 0.197 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 6.351207e-01 | 0.197 | 1 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 6.357738e-01 | 0.197 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 6.357738e-01 | 0.197 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 6.357738e-01 | 0.197 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 6.357738e-01 | 0.197 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 6.357738e-01 | 0.197 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 6.357738e-01 | 0.197 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 6.438565e-01 | 0.191 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 6.454695e-01 | 0.190 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 6.466034e-01 | 0.189 | 1 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 6.468786e-01 | 0.189 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 6.468786e-01 | 0.189 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 6.468786e-01 | 0.189 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 6.468786e-01 | 0.189 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 6.468786e-01 | 0.189 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 6.468786e-01 | 0.189 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 6.468786e-01 | 0.189 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 6.468786e-01 | 0.189 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 6.468786e-01 | 0.189 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 6.468786e-01 | 0.189 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 6.468786e-01 | 0.189 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 6.474743e-01 | 0.189 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 6.474743e-01 | 0.189 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 6.479602e-01 | 0.188 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 6.482660e-01 | 0.188 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 6.482660e-01 | 0.188 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 6.482660e-01 | 0.188 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 6.482660e-01 | 0.188 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 6.482660e-01 | 0.188 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 6.482660e-01 | 0.188 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 6.482660e-01 | 0.188 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 6.482660e-01 | 0.188 | 0 | 0 |
| Lipid particle organization | R-HSA-8964572 | 6.482660e-01 | 0.188 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 6.486694e-01 | 0.188 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 6.538166e-01 | 0.185 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 6.538166e-01 | 0.185 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 6.538166e-01 | 0.185 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 6.538759e-01 | 0.185 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 6.538759e-01 | 0.185 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 6.552539e-01 | 0.184 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 6.578931e-01 | 0.182 | 1 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 6.578931e-01 | 0.182 | 1 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 6.624728e-01 | 0.179 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 6.624728e-01 | 0.179 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 6.641645e-01 | 0.178 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 6.706720e-01 | 0.173 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 6.712779e-01 | 0.173 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 6.712779e-01 | 0.173 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 6.712779e-01 | 0.173 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 6.712779e-01 | 0.173 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 6.712779e-01 | 0.173 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 6.712779e-01 | 0.173 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 6.727772e-01 | 0.172 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 6.742165e-01 | 0.171 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 6.742165e-01 | 0.171 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 6.742165e-01 | 0.171 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 6.742165e-01 | 0.171 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 6.742165e-01 | 0.171 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 6.742165e-01 | 0.171 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 6.742165e-01 | 0.171 | 0 | 0 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 6.742165e-01 | 0.171 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 6.742165e-01 | 0.171 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 6.742165e-01 | 0.171 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 6.760608e-01 | 0.170 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 6.760608e-01 | 0.170 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 6.760608e-01 | 0.170 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 6.760608e-01 | 0.170 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 6.781753e-01 | 0.169 | 1 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 6.781753e-01 | 0.169 | 1 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 6.786987e-01 | 0.168 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 6.798916e-01 | 0.168 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 6.815192e-01 | 0.167 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 6.815192e-01 | 0.167 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 6.815192e-01 | 0.167 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 6.815192e-01 | 0.167 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 6.819384e-01 | 0.166 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 6.828616e-01 | 0.166 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 6.828616e-01 | 0.166 | 1 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 6.857127e-01 | 0.164 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 6.868315e-01 | 0.163 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 6.868315e-01 | 0.163 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 6.868315e-01 | 0.163 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 6.868315e-01 | 0.163 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 6.868315e-01 | 0.163 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 6.868315e-01 | 0.163 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 6.868315e-01 | 0.163 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 6.868315e-01 | 0.163 | 0 | 0 |
| mRNA Editing: C to U Conversion | R-HSA-72200 | 6.868315e-01 | 0.163 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.868315e-01 | 0.163 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 6.868315e-01 | 0.163 | 0 | 0 |
| Activation of TRKA receptors | R-HSA-187015 | 6.868315e-01 | 0.163 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 6.868315e-01 | 0.163 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 6.868315e-01 | 0.163 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 6.868315e-01 | 0.163 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 6.875601e-01 | 0.163 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 6.905481e-01 | 0.161 | 1 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 6.951330e-01 | 0.158 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 6.955919e-01 | 0.158 | 1 | 0 |
| Potassium Channels | R-HSA-1296071 | 6.958986e-01 | 0.157 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 6.961399e-01 | 0.157 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 6.961399e-01 | 0.157 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 6.961399e-01 | 0.157 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 6.971762e-01 | 0.157 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 6.971762e-01 | 0.157 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 6.971762e-01 | 0.157 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 6.971762e-01 | 0.157 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 6.971762e-01 | 0.157 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.997987e-01 | 0.155 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 6.997987e-01 | 0.155 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 6.997987e-01 | 0.155 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 6.997987e-01 | 0.155 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 6.998071e-01 | 0.155 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 6.998071e-01 | 0.155 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 6.998071e-01 | 0.155 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 7.044191e-01 | 0.152 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 7.070767e-01 | 0.151 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 7.086303e-01 | 0.150 | 1 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 7.086303e-01 | 0.150 | 1 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 7.102080e-01 | 0.149 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 7.172304e-01 | 0.144 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 7.172304e-01 | 0.144 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 7.172304e-01 | 0.144 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 7.173102e-01 | 0.144 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 7.173102e-01 | 0.144 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 7.173102e-01 | 0.144 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 7.173102e-01 | 0.144 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 7.200889e-01 | 0.143 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 7.211705e-01 | 0.142 | 0 | 0 |
| Highly calcium permeable nicotinic acetylcholine receptors | R-HSA-629597 | 7.211705e-01 | 0.142 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 7.211705e-01 | 0.142 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 7.211705e-01 | 0.142 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.211705e-01 | 0.142 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 7.211705e-01 | 0.142 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 7.211705e-01 | 0.142 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 7.211705e-01 | 0.142 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 7.211705e-01 | 0.142 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 7.211705e-01 | 0.142 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 7.216109e-01 | 0.142 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 7.227845e-01 | 0.141 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 7.237047e-01 | 0.140 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 7.237047e-01 | 0.140 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 7.237047e-01 | 0.140 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 7.237047e-01 | 0.140 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 7.237047e-01 | 0.140 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 7.237047e-01 | 0.140 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 7.241373e-01 | 0.140 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 7.275130e-01 | 0.138 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 7.279255e-01 | 0.138 | 0 | 0 |
| S Phase | R-HSA-69242 | 7.293907e-01 | 0.137 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 7.293907e-01 | 0.137 | 1 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 7.320478e-01 | 0.135 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 7.340565e-01 | 0.134 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 7.340565e-01 | 0.134 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 7.340565e-01 | 0.134 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 7.340565e-01 | 0.134 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 7.342860e-01 | 0.134 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 7.351564e-01 | 0.134 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 7.351564e-01 | 0.134 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 7.351564e-01 | 0.134 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 7.351564e-01 | 0.134 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 7.362381e-01 | 0.133 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 7.362381e-01 | 0.133 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 7.362381e-01 | 0.133 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 7.389079e-01 | 0.131 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 7.459730e-01 | 0.127 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 7.459730e-01 | 0.127 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 7.459730e-01 | 0.127 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 7.459730e-01 | 0.127 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 7.459730e-01 | 0.127 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 7.459730e-01 | 0.127 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 7.496236e-01 | 0.125 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 7.500444e-01 | 0.125 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 7.511557e-01 | 0.124 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 7.517461e-01 | 0.124 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 7.517461e-01 | 0.124 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 7.517461e-01 | 0.124 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 7.517461e-01 | 0.124 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 7.517461e-01 | 0.124 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 7.517461e-01 | 0.124 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 7.517461e-01 | 0.124 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 7.517461e-01 | 0.124 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 7.517461e-01 | 0.124 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 7.517461e-01 | 0.124 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 7.517461e-01 | 0.124 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 7.542198e-01 | 0.123 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 7.542198e-01 | 0.123 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 7.542198e-01 | 0.123 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 7.551340e-01 | 0.122 | 1 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 7.634949e-01 | 0.117 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 7.634949e-01 | 0.117 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 7.634949e-01 | 0.117 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 7.649294e-01 | 0.116 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 7.652839e-01 | 0.116 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 7.654272e-01 | 0.116 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 7.666818e-01 | 0.115 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 7.666818e-01 | 0.115 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 7.666818e-01 | 0.115 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 7.666818e-01 | 0.115 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 7.666818e-01 | 0.115 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 7.680578e-01 | 0.115 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 7.712004e-01 | 0.113 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 7.712004e-01 | 0.113 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 7.721790e-01 | 0.112 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 7.721790e-01 | 0.112 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 7.726542e-01 | 0.112 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 7.767768e-01 | 0.110 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 7.789704e-01 | 0.108 | 0 | 0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | R-HSA-629594 | 7.789704e-01 | 0.108 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 7.789704e-01 | 0.108 | 0 | 0 |
| TET1,2,3 and TDG demethylate DNA | R-HSA-5221030 | 7.789704e-01 | 0.108 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 7.789704e-01 | 0.108 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 7.789704e-01 | 0.108 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 7.789704e-01 | 0.108 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 7.789704e-01 | 0.108 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 7.789704e-01 | 0.108 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 7.789704e-01 | 0.108 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 7.789704e-01 | 0.108 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 7.802652e-01 | 0.108 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 7.850386e-01 | 0.105 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 7.859053e-01 | 0.105 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 7.859053e-01 | 0.105 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 7.859053e-01 | 0.105 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 7.859053e-01 | 0.105 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 7.865217e-01 | 0.104 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 7.872085e-01 | 0.104 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 7.872085e-01 | 0.104 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 7.879855e-01 | 0.103 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 7.879855e-01 | 0.103 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 7.887891e-01 | 0.103 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 7.894779e-01 | 0.103 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 7.935719e-01 | 0.100 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 7.935719e-01 | 0.100 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 7.991621e-01 | 0.097 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 8.013761e-01 | 0.096 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 8.016081e-01 | 0.096 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.022759e-01 | 0.096 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.022759e-01 | 0.096 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 8.032106e-01 | 0.095 | 0 | 0 |
| FGFR2b ligand binding and activation | R-HSA-190377 | 8.032106e-01 | 0.095 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 8.032106e-01 | 0.095 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 8.032106e-01 | 0.095 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 8.032106e-01 | 0.095 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 8.032106e-01 | 0.095 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 8.032106e-01 | 0.095 | 0 | 0 |
| Biosynthesis of DPAn-3-derived maresins | R-HSA-9026290 | 8.032106e-01 | 0.095 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 8.032106e-01 | 0.095 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 8.032106e-01 | 0.095 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 8.037202e-01 | 0.095 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 8.037202e-01 | 0.095 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 8.037202e-01 | 0.095 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 8.037202e-01 | 0.095 | 1 | 1 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 8.037202e-01 | 0.095 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 8.037202e-01 | 0.095 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 8.065143e-01 | 0.093 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 8.066026e-01 | 0.093 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 8.066533e-01 | 0.093 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 8.101316e-01 | 0.091 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 8.190514e-01 | 0.087 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 8.190514e-01 | 0.087 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 8.202042e-01 | 0.086 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 8.202042e-01 | 0.086 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 8.205050e-01 | 0.086 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 8.227424e-01 | 0.085 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 8.240155e-01 | 0.084 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 8.247937e-01 | 0.084 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 8.247937e-01 | 0.084 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 8.247937e-01 | 0.084 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 8.247937e-01 | 0.084 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 8.247937e-01 | 0.084 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 8.247937e-01 | 0.084 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.247937e-01 | 0.084 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.247937e-01 | 0.084 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 8.247937e-01 | 0.084 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.258454e-01 | 0.083 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 8.286761e-01 | 0.082 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 8.297254e-01 | 0.081 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 8.297254e-01 | 0.081 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 8.304243e-01 | 0.081 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 8.304243e-01 | 0.081 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 8.346957e-01 | 0.078 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.349562e-01 | 0.078 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 8.354347e-01 | 0.078 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 8.354347e-01 | 0.078 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 8.354347e-01 | 0.078 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 8.354347e-01 | 0.078 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 8.354347e-01 | 0.078 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 8.421798e-01 | 0.075 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 8.421798e-01 | 0.075 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 8.429669e-01 | 0.074 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 8.440108e-01 | 0.074 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 8.440108e-01 | 0.074 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.440108e-01 | 0.074 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 8.440108e-01 | 0.074 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.440108e-01 | 0.074 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 8.440108e-01 | 0.074 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 8.440108e-01 | 0.074 | 0 | 0 |
| Biosynthesis of DPAn-3-derived protectins and resolvins | R-HSA-9026286 | 8.440108e-01 | 0.074 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 8.440108e-01 | 0.074 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 8.440108e-01 | 0.074 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 8.440108e-01 | 0.074 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 8.440108e-01 | 0.074 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 8.440108e-01 | 0.074 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 8.440108e-01 | 0.074 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 8.440108e-01 | 0.074 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 8.440108e-01 | 0.074 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 8.440108e-01 | 0.074 | 0 | 0 |
| Estrogen biosynthesis | R-HSA-193144 | 8.440108e-01 | 0.074 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.440108e-01 | 0.074 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 8.456806e-01 | 0.073 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.489423e-01 | 0.071 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 8.494885e-01 | 0.071 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 8.494885e-01 | 0.071 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 8.494885e-01 | 0.071 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 8.494885e-01 | 0.071 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 8.523570e-01 | 0.069 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 8.538370e-01 | 0.069 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 8.538370e-01 | 0.069 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 8.568565e-01 | 0.067 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 8.581294e-01 | 0.066 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 8.592539e-01 | 0.066 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 8.592539e-01 | 0.066 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 8.611211e-01 | 0.065 | 0 | 0 |
| FGFR2c ligand binding and activation | R-HSA-190375 | 8.611211e-01 | 0.065 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 8.611211e-01 | 0.065 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 8.611211e-01 | 0.065 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.611211e-01 | 0.065 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 8.611211e-01 | 0.065 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 8.611211e-01 | 0.065 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.611211e-01 | 0.065 | 0 | 0 |
| Mtb iron assimilation by chelation | R-HSA-1222449 | 8.611211e-01 | 0.065 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 8.611211e-01 | 0.065 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 8.611211e-01 | 0.065 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 8.611211e-01 | 0.065 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 8.611211e-01 | 0.065 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 8.611211e-01 | 0.065 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.611211e-01 | 0.065 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 8.622378e-01 | 0.064 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 8.622378e-01 | 0.064 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 8.624404e-01 | 0.064 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 8.624404e-01 | 0.064 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 8.631271e-01 | 0.064 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 8.646747e-01 | 0.063 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 8.647346e-01 | 0.063 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 8.657819e-01 | 0.063 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 8.700466e-01 | 0.060 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 8.700718e-01 | 0.060 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 8.715470e-01 | 0.060 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 8.715470e-01 | 0.060 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 8.715470e-01 | 0.060 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 8.715470e-01 | 0.060 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 8.715470e-01 | 0.060 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 8.743629e-01 | 0.058 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 8.743629e-01 | 0.058 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 8.749101e-01 | 0.058 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 8.749101e-01 | 0.058 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 8.749101e-01 | 0.058 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 8.749101e-01 | 0.058 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.750506e-01 | 0.058 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 8.755153e-01 | 0.058 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.763555e-01 | 0.057 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 8.763555e-01 | 0.057 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 8.763555e-01 | 0.057 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 8.763555e-01 | 0.057 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 8.763555e-01 | 0.057 | 0 | 0 |
| Biosynthesis of E-series 18(R)-resolvins | R-HSA-9023661 | 8.763555e-01 | 0.057 | 0 | 0 |
| Vitamin B2 (riboflavin) metabolism | R-HSA-196843 | 8.763555e-01 | 0.057 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.763555e-01 | 0.057 | 0 | 0 |
| Glycerophospholipid catabolism | R-HSA-6814848 | 8.763555e-01 | 0.057 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 8.763555e-01 | 0.057 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.763555e-01 | 0.057 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 8.763555e-01 | 0.057 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 8.763555e-01 | 0.057 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 8.763555e-01 | 0.057 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 8.763555e-01 | 0.057 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 8.765708e-01 | 0.057 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 8.803085e-01 | 0.055 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 8.833749e-01 | 0.054 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 8.834373e-01 | 0.054 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 8.835581e-01 | 0.054 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 8.844009e-01 | 0.053 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 8.844009e-01 | 0.053 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 8.853260e-01 | 0.053 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 8.853260e-01 | 0.053 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 8.853260e-01 | 0.053 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 8.853260e-01 | 0.053 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 8.859383e-01 | 0.053 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 8.879541e-01 | 0.052 | 1 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 8.885460e-01 | 0.051 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 8.899195e-01 | 0.051 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 8.899195e-01 | 0.051 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 8.899195e-01 | 0.051 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 8.899195e-01 | 0.051 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 8.899195e-01 | 0.051 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 8.899195e-01 | 0.051 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 8.899195e-01 | 0.051 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 8.899195e-01 | 0.051 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 8.899195e-01 | 0.051 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 8.899195e-01 | 0.051 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 8.899195e-01 | 0.051 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 8.899195e-01 | 0.051 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 8.899195e-01 | 0.051 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 8.932436e-01 | 0.049 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 8.932436e-01 | 0.049 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 8.945386e-01 | 0.048 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.947788e-01 | 0.048 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 8.953967e-01 | 0.048 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 8.953967e-01 | 0.048 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 8.953967e-01 | 0.048 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 8.953967e-01 | 0.048 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 8.953967e-01 | 0.048 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 8.953967e-01 | 0.048 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 8.962834e-01 | 0.048 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 8.983841e-01 | 0.047 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.994096e-01 | 0.046 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 9.013436e-01 | 0.045 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 9.014740e-01 | 0.045 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 9.014740e-01 | 0.045 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.014740e-01 | 0.045 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 9.019962e-01 | 0.045 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 9.019962e-01 | 0.045 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 9.019962e-01 | 0.045 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 9.019962e-01 | 0.045 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 9.019962e-01 | 0.045 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.019962e-01 | 0.045 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 9.019962e-01 | 0.045 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 9.019962e-01 | 0.045 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 9.019962e-01 | 0.045 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.021444e-01 | 0.045 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.046387e-01 | 0.044 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.046387e-01 | 0.044 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.046387e-01 | 0.044 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 9.061886e-01 | 0.043 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 9.071548e-01 | 0.042 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.077634e-01 | 0.042 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 9.077634e-01 | 0.042 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.078576e-01 | 0.042 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 9.091272e-01 | 0.041 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 9.091272e-01 | 0.041 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.091272e-01 | 0.041 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 9.100872e-01 | 0.041 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.103512e-01 | 0.041 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 9.127487e-01 | 0.040 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.127487e-01 | 0.040 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.127487e-01 | 0.040 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 9.127487e-01 | 0.040 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.127487e-01 | 0.040 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 9.127487e-01 | 0.040 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 9.127487e-01 | 0.040 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 9.127487e-01 | 0.040 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 9.127487e-01 | 0.040 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 9.127487e-01 | 0.040 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 9.127487e-01 | 0.040 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 9.127487e-01 | 0.040 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.131127e-01 | 0.039 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 9.131127e-01 | 0.039 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 9.131127e-01 | 0.039 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 9.131424e-01 | 0.039 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 9.162369e-01 | 0.038 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.162369e-01 | 0.038 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 9.167274e-01 | 0.038 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.172448e-01 | 0.038 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.172448e-01 | 0.038 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.172448e-01 | 0.038 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.195140e-01 | 0.036 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.208758e-01 | 0.036 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.212940e-01 | 0.036 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.223220e-01 | 0.035 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.223220e-01 | 0.035 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 9.223220e-01 | 0.035 | 0 | 0 |
| Biosynthesis of aspirin-triggered D-series resolvins | R-HSA-9020265 | 9.223220e-01 | 0.035 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 9.223220e-01 | 0.035 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 9.223220e-01 | 0.035 | 0 | 0 |
| GDP-fucose biosynthesis | R-HSA-6787639 | 9.223220e-01 | 0.035 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 9.223220e-01 | 0.035 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 9.223220e-01 | 0.035 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 9.223220e-01 | 0.035 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 9.223220e-01 | 0.035 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 9.226949e-01 | 0.035 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 9.226949e-01 | 0.035 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.226949e-01 | 0.035 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 9.226949e-01 | 0.035 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.228358e-01 | 0.035 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.228358e-01 | 0.035 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 9.279820e-01 | 0.032 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 9.279820e-01 | 0.032 | 0 | 0 |
| Synthesis of glycosylphosphatidylinositol (GPI) | R-HSA-162710 | 9.279820e-01 | 0.032 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 9.279820e-01 | 0.032 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 9.279820e-01 | 0.032 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.282754e-01 | 0.032 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 9.283910e-01 | 0.032 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 9.289554e-01 | 0.032 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.295858e-01 | 0.032 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.299213e-01 | 0.032 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.300323e-01 | 0.032 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 9.308454e-01 | 0.031 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 9.308454e-01 | 0.031 | 0 | 0 |
| Activated point mutants of FGFR2 | R-HSA-2033519 | 9.308454e-01 | 0.031 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 9.308454e-01 | 0.031 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 9.308454e-01 | 0.031 | 0 | 0 |
| Biosynthesis of Lipoxins (LX) | R-HSA-2142700 | 9.308454e-01 | 0.031 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.308454e-01 | 0.031 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 9.308454e-01 | 0.031 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 9.308454e-01 | 0.031 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 9.308454e-01 | 0.031 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 9.308454e-01 | 0.031 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.309856e-01 | 0.031 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.310316e-01 | 0.031 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 9.334896e-01 | 0.030 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.344820e-01 | 0.029 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 9.346259e-01 | 0.029 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.350592e-01 | 0.029 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 9.359595e-01 | 0.029 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 9.383579e-01 | 0.028 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.383579e-01 | 0.028 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.384340e-01 | 0.028 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 9.384340e-01 | 0.028 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 9.384340e-01 | 0.028 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 9.384340e-01 | 0.028 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.384340e-01 | 0.028 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 9.384340e-01 | 0.028 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 9.384340e-01 | 0.028 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.384340e-01 | 0.028 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 9.391110e-01 | 0.027 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 9.397568e-01 | 0.027 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.399712e-01 | 0.027 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 9.404232e-01 | 0.027 | 0 | 0 |
| Defective B3GALTL causes PpS | R-HSA-5083635 | 9.404232e-01 | 0.027 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 9.410648e-01 | 0.026 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 9.427944e-01 | 0.026 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 9.447331e-01 | 0.025 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 9.451903e-01 | 0.024 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.451903e-01 | 0.024 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 9.451903e-01 | 0.024 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 9.451903e-01 | 0.024 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.458499e-01 | 0.024 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.458499e-01 | 0.024 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 9.458499e-01 | 0.024 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 9.471342e-01 | 0.024 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.471342e-01 | 0.024 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.492235e-01 | 0.023 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 9.497993e-01 | 0.022 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.508034e-01 | 0.022 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.508034e-01 | 0.022 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.508034e-01 | 0.022 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 9.508034e-01 | 0.022 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.510790e-01 | 0.022 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 9.510790e-01 | 0.022 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.510790e-01 | 0.022 | 0 | 0 |
| FGFR2 ligand binding and activation | R-HSA-190241 | 9.512055e-01 | 0.022 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.512055e-01 | 0.022 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 9.512055e-01 | 0.022 | 0 | 0 |
| Biosynthesis of E-series 18(S)-resolvins | R-HSA-9018896 | 9.512055e-01 | 0.022 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.512055e-01 | 0.022 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 9.512055e-01 | 0.022 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 9.512055e-01 | 0.022 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.512055e-01 | 0.022 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 9.512055e-01 | 0.022 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.528937e-01 | 0.021 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.542681e-01 | 0.020 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 9.543069e-01 | 0.020 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.547515e-01 | 0.020 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.547515e-01 | 0.020 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.553224e-01 | 0.020 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.553224e-01 | 0.020 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.564319e-01 | 0.019 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 9.565608e-01 | 0.019 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.565608e-01 | 0.019 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 9.565608e-01 | 0.019 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 9.565608e-01 | 0.019 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.565608e-01 | 0.019 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 9.576267e-01 | 0.019 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 9.581682e-01 | 0.019 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.581682e-01 | 0.019 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.582264e-01 | 0.019 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.594423e-01 | 0.018 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.597400e-01 | 0.018 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.608217e-01 | 0.017 | 0 | 0 |
| Biosynthesis of D-series resolvins | R-HSA-9018676 | 9.613287e-01 | 0.017 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.613287e-01 | 0.017 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.613287e-01 | 0.017 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 9.613287e-01 | 0.017 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.613287e-01 | 0.017 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 9.613449e-01 | 0.017 | 0 | 0 |
| O-glycosylation of TSR domain-containing proteins | R-HSA-5173214 | 9.631964e-01 | 0.016 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.631964e-01 | 0.016 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.631964e-01 | 0.016 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.631964e-01 | 0.016 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.655735e-01 | 0.015 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 9.655735e-01 | 0.015 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.655735e-01 | 0.015 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 9.655735e-01 | 0.015 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.655735e-01 | 0.015 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.655735e-01 | 0.015 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 9.659650e-01 | 0.015 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.666154e-01 | 0.015 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.669947e-01 | 0.015 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.684160e-01 | 0.014 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.693526e-01 | 0.014 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 9.693526e-01 | 0.014 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.693526e-01 | 0.014 | 0 | 0 |
| Synthesis of dolichyl-phosphate | R-HSA-446199 | 9.693526e-01 | 0.014 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.697274e-01 | 0.013 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.697274e-01 | 0.013 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 9.697591e-01 | 0.013 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.697591e-01 | 0.013 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 9.697591e-01 | 0.013 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.702482e-01 | 0.013 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 9.707028e-01 | 0.013 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.707070e-01 | 0.013 | 1 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.717480e-01 | 0.012 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.724519e-01 | 0.012 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.725588e-01 | 0.012 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.727170e-01 | 0.012 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.727170e-01 | 0.012 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.727170e-01 | 0.012 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.727170e-01 | 0.012 | 0 | 0 |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | R-HSA-9027604 | 9.727170e-01 | 0.012 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.741281e-01 | 0.011 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.751336e-01 | 0.011 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 9.751336e-01 | 0.011 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.755760e-01 | 0.011 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 9.756040e-01 | 0.011 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.757123e-01 | 0.011 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 9.757123e-01 | 0.011 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.757123e-01 | 0.011 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.757123e-01 | 0.011 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.757123e-01 | 0.011 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 9.761545e-01 | 0.010 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.761545e-01 | 0.010 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 9.767956e-01 | 0.010 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.774740e-01 | 0.010 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.778064e-01 | 0.010 | 0 | 0 |
| Biosynthesis of DPAn-3 SPMs | R-HSA-9025094 | 9.783789e-01 | 0.009 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 9.783789e-01 | 0.009 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.783789e-01 | 0.009 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.783789e-01 | 0.009 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.787728e-01 | 0.009 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.796004e-01 | 0.009 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.796004e-01 | 0.009 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.796004e-01 | 0.009 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.796004e-01 | 0.009 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.802184e-01 | 0.009 | 1 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.807529e-01 | 0.008 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.807529e-01 | 0.008 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.815316e-01 | 0.008 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.828663e-01 | 0.008 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.828663e-01 | 0.008 | 0 | 0 |
| Biosynthesis of EPA-derived SPMs | R-HSA-9018679 | 9.828663e-01 | 0.008 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.828663e-01 | 0.008 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.828663e-01 | 0.008 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 9.832847e-01 | 0.007 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.832847e-01 | 0.007 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.837853e-01 | 0.007 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 9.843228e-01 | 0.007 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 9.847478e-01 | 0.007 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.847478e-01 | 0.007 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.848757e-01 | 0.007 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.848757e-01 | 0.007 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.854999e-01 | 0.006 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 9.864227e-01 | 0.006 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.864227e-01 | 0.006 | 0 | 0 |
| Biosynthesis of DPA-derived SPMs | R-HSA-9018683 | 9.864227e-01 | 0.006 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.864227e-01 | 0.006 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.864741e-01 | 0.006 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 9.864787e-01 | 0.006 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 9.866706e-01 | 0.006 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.876278e-01 | 0.005 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.876525e-01 | 0.005 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 9.879138e-01 | 0.005 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.879138e-01 | 0.005 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.879138e-01 | 0.005 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 9.888142e-01 | 0.005 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 9.896141e-01 | 0.005 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.896664e-01 | 0.005 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.896664e-01 | 0.005 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.896664e-01 | 0.005 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.904230e-01 | 0.004 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 9.912937e-01 | 0.004 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.914750e-01 | 0.004 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.914750e-01 | 0.004 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.914750e-01 | 0.004 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.914750e-01 | 0.004 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.914750e-01 | 0.004 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.916416e-01 | 0.004 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 9.916454e-01 | 0.004 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.917454e-01 | 0.004 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.922083e-01 | 0.003 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.924095e-01 | 0.003 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.924114e-01 | 0.003 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.924114e-01 | 0.003 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.924114e-01 | 0.003 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.924114e-01 | 0.003 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 9.924114e-01 | 0.003 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 9.927143e-01 | 0.003 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.932451e-01 | 0.003 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.932451e-01 | 0.003 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.932451e-01 | 0.003 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.932669e-01 | 0.003 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.936887e-01 | 0.003 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.936887e-01 | 0.003 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 9.939872e-01 | 0.003 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.939872e-01 | 0.003 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.939872e-01 | 0.003 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.939872e-01 | 0.003 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.941094e-01 | 0.003 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.941094e-01 | 0.003 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.942712e-01 | 0.002 | 1 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.943218e-01 | 0.002 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 9.944503e-01 | 0.002 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.945126e-01 | 0.002 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.946367e-01 | 0.002 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.946367e-01 | 0.002 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.946478e-01 | 0.002 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.952359e-01 | 0.002 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.952359e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.952359e-01 | 0.002 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.952660e-01 | 0.002 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.952764e-01 | 0.002 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.952985e-01 | 0.002 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.953829e-01 | 0.002 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.955314e-01 | 0.002 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.955314e-01 | 0.002 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.958587e-01 | 0.002 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.961489e-01 | 0.002 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.962254e-01 | 0.002 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.962254e-01 | 0.002 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.963236e-01 | 0.002 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.963639e-01 | 0.002 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.963692e-01 | 0.002 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.967209e-01 | 0.001 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.967209e-01 | 0.001 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.972374e-01 | 0.001 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.973381e-01 | 0.001 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.973381e-01 | 0.001 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.973381e-01 | 0.001 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.974263e-01 | 0.001 | 1 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.974603e-01 | 0.001 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.976307e-01 | 0.001 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.976307e-01 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.976472e-01 | 0.001 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.978776e-01 | 0.001 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.978911e-01 | 0.001 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.978911e-01 | 0.001 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 9.983293e-01 | 0.001 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.983355e-01 | 0.001 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.984170e-01 | 0.001 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.985070e-01 | 0.001 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.985130e-01 | 0.001 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.985130e-01 | 0.001 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.985743e-01 | 0.001 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.986765e-01 | 0.001 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.986765e-01 | 0.001 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.986765e-01 | 0.001 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.989515e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.989594e-01 | 0.000 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.989915e-01 | 0.000 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.991762e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.992938e-01 | 0.000 | 0 | 0 |
| Digestion | R-HSA-8935690 | 9.994145e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.994295e-01 | 0.000 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.995216e-01 | 0.000 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.995547e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.995872e-01 | 0.000 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.996326e-01 | 0.000 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.996326e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.996388e-01 | 0.000 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.996661e-01 | 0.000 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.997410e-01 | 0.000 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.997617e-01 | 0.000 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.997934e-01 | 0.000 | 0 | 0 |
| Latent infection - Other responses of Mtb to phagocytosis | R-HSA-1222499 | 9.997949e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.998376e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.998703e-01 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.998797e-01 | 0.000 | 1 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.998981e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.998981e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.999093e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.999193e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999288e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999290e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.999361e-01 | 0.000 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.999361e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999477e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999477e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999550e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999578e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.999599e-01 | 0.000 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.999615e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999683e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999755e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999776e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999816e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999843e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999875e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999886e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999901e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999938e-01 | 0.000 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.999967e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999973e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.999974e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999975e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999979e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999980e-01 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.999993e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999993e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999993e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999993e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.999994e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999994e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999996e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.999997e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999997e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999998e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999999e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999999e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999999e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999999e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999999e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999999e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 1.000000e+00 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| RSK activation | R-HSA-444257 | 1.000000e+00 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle, Mitotic | R-HSA-69278 | 3.552714e-15 | 14.449 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.554312e-14 | 13.808 | 0 | 0 |
| M Phase | R-HSA-68886 | 2.753353e-14 | 13.560 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 2.234879e-13 | 12.651 | 1 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 3.638201e-13 | 12.439 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 3.873568e-13 | 12.412 | 1 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 4.160783e-12 | 11.381 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 3.221912e-11 | 10.492 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 7.169842e-11 | 10.144 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.383639e-10 | 9.859 | 1 | 1 |
| Axon guidance | R-HSA-422475 | 2.742573e-10 | 9.562 | 1 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.017995e-09 | 8.992 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 1.024897e-09 | 8.989 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.162507e-09 | 8.935 | 0 | 0 |
| Kinesins | R-HSA-983189 | 2.129093e-09 | 8.672 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 3.500564e-09 | 8.456 | 1 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 4.794839e-09 | 8.319 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 5.503654e-09 | 8.259 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 9.415481e-09 | 8.026 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.108862e-08 | 7.955 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.225046e-08 | 7.912 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.064053e-08 | 7.685 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.986841e-08 | 7.702 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 2.423195e-08 | 7.616 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 4.270301e-08 | 7.370 | 1 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 4.135720e-08 | 7.383 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 5.294631e-08 | 7.276 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 5.739496e-08 | 7.241 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 6.632920e-08 | 7.178 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 9.899269e-08 | 7.004 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.173536e-07 | 6.931 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 1.378336e-07 | 6.861 | 1 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 1.460280e-07 | 6.836 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 1.526365e-07 | 6.816 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.697807e-07 | 6.770 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.145097e-07 | 6.669 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.203411e-07 | 6.657 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 2.491046e-07 | 6.604 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.712771e-07 | 6.567 | 1 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 3.151641e-07 | 6.501 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 3.180252e-07 | 6.498 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 3.416458e-07 | 6.466 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 3.758043e-07 | 6.425 | 1 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 3.905987e-07 | 6.408 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 3.876589e-07 | 6.412 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 4.104588e-07 | 6.387 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 5.743899e-07 | 6.241 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 5.787639e-07 | 6.237 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 7.421343e-07 | 6.130 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.051918e-06 | 5.978 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 1.097839e-06 | 5.959 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.249941e-06 | 5.903 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.314072e-06 | 5.881 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.462148e-06 | 5.835 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.522470e-06 | 5.817 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.842147e-06 | 5.735 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.805229e-06 | 5.743 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.923633e-06 | 5.716 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 2.063318e-06 | 5.685 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 2.177827e-06 | 5.662 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 2.177827e-06 | 5.662 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 2.277774e-06 | 5.642 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.470106e-06 | 5.607 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 2.532482e-06 | 5.596 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 2.776467e-06 | 5.557 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 3.397038e-06 | 5.469 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.397038e-06 | 5.469 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 3.339355e-06 | 5.476 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 3.476374e-06 | 5.459 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 3.487674e-06 | 5.457 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 4.030340e-06 | 5.395 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 3.973571e-06 | 5.401 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.196845e-06 | 5.377 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 4.469126e-06 | 5.350 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 4.517214e-06 | 5.345 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 4.543947e-06 | 5.343 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 4.813943e-06 | 5.317 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.035531e-06 | 5.298 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 8.776279e-06 | 5.057 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 8.916954e-06 | 5.050 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 9.239248e-06 | 5.034 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 9.747372e-06 | 5.011 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 1.036797e-05 | 4.984 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.087686e-05 | 4.963 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 1.184702e-05 | 4.926 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 1.184702e-05 | 4.926 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.144039e-05 | 4.942 | 1 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.208011e-05 | 4.918 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.210648e-05 | 4.917 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.246959e-05 | 4.904 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.361351e-05 | 4.866 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.361351e-05 | 4.866 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.306230e-05 | 4.884 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 1.288601e-05 | 4.890 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.372310e-05 | 4.863 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 1.481619e-05 | 4.829 | 1 | 1 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.507748e-05 | 4.822 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.866777e-05 | 4.729 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.982528e-05 | 4.703 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.141294e-05 | 4.669 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.420312e-05 | 4.616 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.420312e-05 | 4.616 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.573966e-05 | 4.589 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 2.583003e-05 | 4.588 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 2.784614e-05 | 4.555 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 2.795154e-05 | 4.554 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 2.798289e-05 | 4.553 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 2.817605e-05 | 4.550 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 3.058536e-05 | 4.514 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 3.102346e-05 | 4.508 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 2.968690e-05 | 4.527 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 3.141363e-05 | 4.503 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 3.610573e-05 | 4.442 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 3.664597e-05 | 4.436 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 3.917273e-05 | 4.407 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 3.917273e-05 | 4.407 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 3.927420e-05 | 4.406 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 3.937686e-05 | 4.405 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 3.992214e-05 | 4.399 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 4.276531e-05 | 4.369 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 5.301367e-05 | 4.276 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 5.338190e-05 | 4.273 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 5.795794e-05 | 4.237 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 5.880126e-05 | 4.231 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 6.918920e-05 | 4.160 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 6.978889e-05 | 4.156 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 6.918920e-05 | 4.160 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 6.953444e-05 | 4.158 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 7.345203e-05 | 4.134 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 8.205728e-05 | 4.086 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 8.205728e-05 | 4.086 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 8.327338e-05 | 4.079 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 8.463028e-05 | 4.072 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.571420e-05 | 4.019 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 9.634356e-05 | 4.016 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.760010e-05 | 4.011 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 1.190608e-04 | 3.924 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.223892e-04 | 3.912 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 1.202346e-04 | 3.920 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 1.238353e-04 | 3.907 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 1.278774e-04 | 3.893 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 1.278774e-04 | 3.893 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 1.353953e-04 | 3.868 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 1.356073e-04 | 3.868 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.491006e-04 | 3.827 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.560777e-04 | 3.807 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.639821e-04 | 3.785 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.655179e-04 | 3.781 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.717196e-04 | 3.765 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 1.750792e-04 | 3.757 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 1.786249e-04 | 3.748 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.786274e-04 | 3.748 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 1.970382e-04 | 3.705 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 2.134705e-04 | 3.671 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 2.261176e-04 | 3.646 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 2.280016e-04 | 3.642 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 2.372746e-04 | 3.625 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 2.392888e-04 | 3.621 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 2.501259e-04 | 3.602 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 2.928907e-04 | 3.533 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 2.980895e-04 | 3.526 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 3.149064e-04 | 3.502 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 3.153418e-04 | 3.501 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 3.530527e-04 | 3.452 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 3.577420e-04 | 3.446 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 4.233263e-04 | 3.373 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 4.013464e-04 | 3.396 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.233263e-04 | 3.373 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 4.233263e-04 | 3.373 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 3.813201e-04 | 3.419 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 4.629390e-04 | 3.334 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.632865e-04 | 3.334 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.652362e-04 | 3.332 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 4.877421e-04 | 3.312 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 5.180320e-04 | 3.286 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 5.271466e-04 | 3.278 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 5.271466e-04 | 3.278 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 5.299843e-04 | 3.276 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 5.675843e-04 | 3.246 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 5.675843e-04 | 3.246 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 5.675843e-04 | 3.246 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 5.675843e-04 | 3.246 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 6.049253e-04 | 3.218 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 5.914549e-04 | 3.228 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 5.881126e-04 | 3.231 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 6.273193e-04 | 3.203 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 6.483657e-04 | 3.188 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 6.691562e-04 | 3.174 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 6.737555e-04 | 3.171 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 7.074952e-04 | 3.150 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 7.142406e-04 | 3.146 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 7.373709e-04 | 3.132 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 7.452344e-04 | 3.128 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 8.049601e-04 | 3.094 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 8.560433e-04 | 3.068 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 8.560433e-04 | 3.068 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 8.922326e-04 | 3.050 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 8.922326e-04 | 3.050 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 9.186940e-04 | 3.037 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 9.300024e-04 | 3.032 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.007186e-03 | 2.997 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.056074e-03 | 2.976 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 9.712072e-04 | 3.013 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 9.887052e-04 | 3.005 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.056074e-03 | 2.976 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.067691e-03 | 2.972 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.067844e-03 | 2.971 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.077466e-03 | 2.968 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.157268e-03 | 2.937 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.169478e-03 | 2.932 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.170686e-03 | 2.932 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.170686e-03 | 2.932 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.207375e-03 | 2.918 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 1.318738e-03 | 2.880 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 1.318738e-03 | 2.880 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.355970e-03 | 2.868 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.376530e-03 | 2.861 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 1.376530e-03 | 2.861 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.426174e-03 | 2.846 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.426268e-03 | 2.846 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 1.497715e-03 | 2.825 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.509679e-03 | 2.821 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.511550e-03 | 2.821 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.514037e-03 | 2.820 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 1.565565e-03 | 2.805 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.681168e-03 | 2.774 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 1.684445e-03 | 2.774 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.757572e-03 | 2.755 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.833730e-03 | 2.737 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 1.853864e-03 | 2.732 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.855737e-03 | 2.731 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.867351e-03 | 2.729 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 1.990672e-03 | 2.701 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 2.024475e-03 | 2.694 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 2.031149e-03 | 2.692 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 2.342027e-03 | 2.630 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 2.342027e-03 | 2.630 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.376798e-03 | 2.624 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 2.429313e-03 | 2.615 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 2.429313e-03 | 2.615 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 2.498623e-03 | 2.602 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 2.546514e-03 | 2.594 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 2.678799e-03 | 2.572 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 2.739790e-03 | 2.562 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 2.783559e-03 | 2.555 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 2.785463e-03 | 2.555 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 2.792221e-03 | 2.554 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 2.792221e-03 | 2.554 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 2.792221e-03 | 2.554 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 2.903192e-03 | 2.537 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.008777e-03 | 2.522 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.008777e-03 | 2.522 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 3.160341e-03 | 2.500 | 1 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.356669e-03 | 2.474 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 3.433321e-03 | 2.464 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 3.497575e-03 | 2.456 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 3.543250e-03 | 2.451 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 3.634668e-03 | 2.440 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 3.634668e-03 | 2.440 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 3.746624e-03 | 2.426 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 3.764366e-03 | 2.424 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 3.772389e-03 | 2.423 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 3.787459e-03 | 2.422 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 3.867397e-03 | 2.413 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 3.954351e-03 | 2.403 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 4.023769e-03 | 2.395 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 4.065729e-03 | 2.391 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 4.109332e-03 | 2.386 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 4.339412e-03 | 2.363 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 4.523135e-03 | 2.345 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 4.563584e-03 | 2.341 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 4.563584e-03 | 2.341 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 4.880422e-03 | 2.312 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 5.157557e-03 | 2.288 | 1 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 5.089042e-03 | 2.293 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 5.297117e-03 | 2.276 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 5.343622e-03 | 2.272 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 5.437058e-03 | 2.265 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 5.567529e-03 | 2.254 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 5.583044e-03 | 2.253 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 5.606018e-03 | 2.251 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 5.672116e-03 | 2.246 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 5.672116e-03 | 2.246 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 5.679524e-03 | 2.246 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 5.736670e-03 | 2.241 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 5.784543e-03 | 2.238 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 5.821506e-03 | 2.235 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 5.853091e-03 | 2.233 | 1 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 6.011448e-03 | 2.221 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 6.097929e-03 | 2.215 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 6.256846e-03 | 2.204 | 0 | 0 |
| S Phase | R-HSA-69242 | 6.335657e-03 | 2.198 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 6.531365e-03 | 2.185 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 6.531365e-03 | 2.185 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 6.531365e-03 | 2.185 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 6.651948e-03 | 2.177 | 0 | 0 |
| Protein folding | R-HSA-391251 | 6.881007e-03 | 2.162 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 6.887828e-03 | 2.162 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 6.887828e-03 | 2.162 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 6.927532e-03 | 2.159 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 6.950624e-03 | 2.158 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 6.965116e-03 | 2.157 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 7.078217e-03 | 2.150 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 7.236020e-03 | 2.141 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 7.591658e-03 | 2.120 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 7.591658e-03 | 2.120 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 8.092735e-03 | 2.092 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 8.422435e-03 | 2.075 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 9.742931e-03 | 2.011 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 8.536417e-03 | 2.069 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.064202e-02 | 1.973 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 9.945098e-03 | 2.002 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.052758e-02 | 1.978 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 9.701864e-03 | 2.013 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 9.701864e-03 | 2.013 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.003308e-03 | 2.046 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 8.536417e-03 | 2.069 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.032775e-02 | 1.986 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 9.750501e-03 | 2.011 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 8.536417e-03 | 2.069 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.053511e-02 | 1.977 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 9.959520e-03 | 2.002 | 1 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 8.536417e-03 | 2.069 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.071541e-02 | 1.970 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 1.077566e-02 | 1.968 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 1.081134e-02 | 1.966 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.132738e-02 | 1.946 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.144570e-02 | 1.941 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.144570e-02 | 1.941 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 1.177601e-02 | 1.929 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.177601e-02 | 1.929 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 1.177601e-02 | 1.929 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 1.209435e-02 | 1.917 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 1.210879e-02 | 1.917 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.210879e-02 | 1.917 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.222920e-02 | 1.913 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.222920e-02 | 1.913 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 1.261509e-02 | 1.899 | 1 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.284486e-02 | 1.891 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.336814e-02 | 1.874 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 1.340172e-02 | 1.873 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 1.348479e-02 | 1.870 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 1.385139e-02 | 1.859 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 1.386675e-02 | 1.858 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.395073e-02 | 1.855 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.463083e-02 | 1.835 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.463083e-02 | 1.835 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.463083e-02 | 1.835 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.463083e-02 | 1.835 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.463083e-02 | 1.835 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.477199e-02 | 1.831 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.495282e-02 | 1.825 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.495282e-02 | 1.825 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.518875e-02 | 1.818 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.521580e-02 | 1.818 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 1.535756e-02 | 1.814 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 1.584986e-02 | 1.800 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 1.616378e-02 | 1.791 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.623538e-02 | 1.790 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 1.623538e-02 | 1.790 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.623538e-02 | 1.790 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 1.642252e-02 | 1.785 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 1.642252e-02 | 1.785 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 1.642252e-02 | 1.785 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.644499e-02 | 1.784 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.682422e-02 | 1.774 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 1.738075e-02 | 1.760 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.765199e-02 | 1.753 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 1.890826e-02 | 1.723 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 1.890826e-02 | 1.723 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 2.389407e-02 | 1.622 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 2.162414e-02 | 1.665 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 1.907539e-02 | 1.720 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 2.365350e-02 | 1.626 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 2.389407e-02 | 1.622 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.112723e-02 | 1.675 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 2.030346e-02 | 1.692 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 2.068289e-02 | 1.684 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 2.365350e-02 | 1.626 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 2.213813e-02 | 1.655 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 2.213813e-02 | 1.655 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.389407e-02 | 1.622 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.890826e-02 | 1.723 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 1.853820e-02 | 1.732 | 1 | 0 |
| MTOR signalling | R-HSA-165159 | 1.793438e-02 | 1.746 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 1.853820e-02 | 1.732 | 1 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 2.068289e-02 | 1.684 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 1.951366e-02 | 1.710 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.213819e-02 | 1.655 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 1.880035e-02 | 1.726 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.890826e-02 | 1.723 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 2.162414e-02 | 1.665 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.793438e-02 | 1.746 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.269821e-02 | 1.644 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 2.368367e-02 | 1.626 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.139521e-02 | 1.670 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.139521e-02 | 1.670 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 2.179604e-02 | 1.662 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 2.365350e-02 | 1.626 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.336279e-02 | 1.631 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 1.890826e-02 | 1.723 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 1.993380e-02 | 1.700 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 2.399014e-02 | 1.620 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 2.421613e-02 | 1.616 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 2.457430e-02 | 1.610 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 2.457430e-02 | 1.610 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 2.457430e-02 | 1.610 | 1 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 2.497491e-02 | 1.602 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 2.497491e-02 | 1.602 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.497491e-02 | 1.602 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 2.498695e-02 | 1.602 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 2.539616e-02 | 1.595 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 2.560619e-02 | 1.592 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 2.560619e-02 | 1.592 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.585717e-02 | 1.587 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 2.622117e-02 | 1.581 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 2.657215e-02 | 1.576 | 1 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 2.678569e-02 | 1.572 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 2.721950e-02 | 1.565 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 2.722312e-02 | 1.565 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.739256e-02 | 1.562 | 1 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 2.825905e-02 | 1.549 | 1 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 2.827412e-02 | 1.549 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 2.890833e-02 | 1.539 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 2.940464e-02 | 1.532 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 2.942245e-02 | 1.531 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 2.942245e-02 | 1.531 | 1 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 3.032770e-02 | 1.518 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 3.056685e-02 | 1.515 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 3.104328e-02 | 1.508 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.122173e-02 | 1.506 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 3.122173e-02 | 1.506 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 3.122173e-02 | 1.506 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 3.122173e-02 | 1.506 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 3.122173e-02 | 1.506 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 3.149500e-02 | 1.502 | 1 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 3.195032e-02 | 1.496 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.207822e-02 | 1.494 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 3.208950e-02 | 1.494 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 3.208950e-02 | 1.494 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 3.208950e-02 | 1.494 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 3.217527e-02 | 1.492 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 3.325988e-02 | 1.478 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.325988e-02 | 1.478 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 3.331869e-02 | 1.477 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 3.331869e-02 | 1.477 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 3.331869e-02 | 1.477 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 3.362987e-02 | 1.473 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 3.363231e-02 | 1.473 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 3.393334e-02 | 1.469 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.393334e-02 | 1.469 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 3.393334e-02 | 1.469 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 3.744534e-02 | 1.427 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 4.994860e-02 | 1.301 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 4.953583e-02 | 1.305 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 3.755236e-02 | 1.425 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 4.461443e-02 | 1.351 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 4.486730e-02 | 1.348 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 4.322137e-02 | 1.364 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 3.621736e-02 | 1.441 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 4.885294e-02 | 1.311 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 3.782406e-02 | 1.422 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 5.074184e-02 | 1.295 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 3.512554e-02 | 1.454 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 5.095083e-02 | 1.293 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 4.722137e-02 | 1.326 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 3.512337e-02 | 1.454 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 4.691311e-02 | 1.329 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 3.621736e-02 | 1.441 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 3.849558e-02 | 1.415 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 4.655387e-02 | 1.332 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 4.953583e-02 | 1.305 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 5.074184e-02 | 1.295 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 4.070184e-02 | 1.390 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 3.782406e-02 | 1.422 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 3.782406e-02 | 1.422 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 4.865715e-02 | 1.313 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 3.882024e-02 | 1.411 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 4.486730e-02 | 1.348 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 5.074184e-02 | 1.295 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 3.755236e-02 | 1.425 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 4.322137e-02 | 1.364 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 3.621736e-02 | 1.441 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 3.733472e-02 | 1.428 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 5.147012e-02 | 1.288 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 3.894095e-02 | 1.410 | 1 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 3.894095e-02 | 1.410 | 1 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 4.662067e-02 | 1.331 | 1 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 3.755236e-02 | 1.425 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 4.070184e-02 | 1.390 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 4.662067e-02 | 1.331 | 1 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 3.744534e-02 | 1.427 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 3.621736e-02 | 1.441 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 5.095083e-02 | 1.293 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 3.782406e-02 | 1.422 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 3.882024e-02 | 1.411 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.757947e-02 | 1.425 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 3.621736e-02 | 1.441 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 3.621736e-02 | 1.441 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 4.172700e-02 | 1.380 | 1 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 4.461443e-02 | 1.351 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 4.087735e-02 | 1.389 | 1 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 3.492520e-02 | 1.457 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 4.341354e-02 | 1.362 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 4.940634e-02 | 1.306 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 4.655387e-02 | 1.332 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 3.487994e-02 | 1.457 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 3.512554e-02 | 1.454 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 3.882024e-02 | 1.411 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 3.512554e-02 | 1.454 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 4.394934e-02 | 1.357 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 3.882024e-02 | 1.411 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 3.882024e-02 | 1.411 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 5.199941e-02 | 1.284 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 5.199941e-02 | 1.284 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 5.199941e-02 | 1.284 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 5.199941e-02 | 1.284 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 5.199941e-02 | 1.284 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 5.199941e-02 | 1.284 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 5.241776e-02 | 1.281 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 5.241776e-02 | 1.281 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 5.446796e-02 | 1.264 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 5.463810e-02 | 1.263 | 1 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 5.473971e-02 | 1.262 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 5.492941e-02 | 1.260 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 5.492941e-02 | 1.260 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 5.492941e-02 | 1.260 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 5.560119e-02 | 1.255 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 5.563632e-02 | 1.255 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 5.563632e-02 | 1.255 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 5.631161e-02 | 1.249 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 5.639010e-02 | 1.249 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 5.690409e-02 | 1.245 | 1 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 5.691693e-02 | 1.245 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 5.851141e-02 | 1.233 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 5.862545e-02 | 1.232 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 5.863550e-02 | 1.232 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 5.863550e-02 | 1.232 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 5.889769e-02 | 1.230 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 5.986760e-02 | 1.223 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 5.986760e-02 | 1.223 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 5.986760e-02 | 1.223 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 6.096580e-02 | 1.215 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 6.181269e-02 | 1.209 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 6.225507e-02 | 1.206 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 6.225507e-02 | 1.206 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 6.225507e-02 | 1.206 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 6.303203e-02 | 1.200 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 6.303203e-02 | 1.200 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 6.421178e-02 | 1.192 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 6.636677e-02 | 1.178 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 6.636677e-02 | 1.178 | 0 | 0 |
| Translation | R-HSA-72766 | 6.726316e-02 | 1.172 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 6.755648e-02 | 1.170 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 6.843760e-02 | 1.165 | 1 | 1 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 6.843760e-02 | 1.165 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 6.843760e-02 | 1.165 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 6.843760e-02 | 1.165 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 6.843760e-02 | 1.165 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.849375e-02 | 1.164 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 6.857588e-02 | 1.164 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 6.857588e-02 | 1.164 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 6.857588e-02 | 1.164 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.908554e-02 | 1.161 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 6.969371e-02 | 1.157 | 1 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 7.025587e-02 | 1.153 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 7.025587e-02 | 1.153 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 7.124987e-02 | 1.147 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 7.135427e-02 | 1.147 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 7.154160e-02 | 1.145 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 7.362410e-02 | 1.133 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 7.466388e-02 | 1.127 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 7.527622e-02 | 1.123 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 7.582683e-02 | 1.120 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 7.582683e-02 | 1.120 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 7.587423e-02 | 1.120 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 7.587423e-02 | 1.120 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 7.664115e-02 | 1.116 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 7.664115e-02 | 1.116 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 7.907597e-02 | 1.102 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 8.001714e-02 | 1.097 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 8.012434e-02 | 1.096 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 8.027944e-02 | 1.095 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 8.111692e-02 | 1.091 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 8.235685e-02 | 1.084 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 8.365184e-02 | 1.078 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 8.376561e-02 | 1.077 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 8.376561e-02 | 1.077 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 8.376561e-02 | 1.077 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 8.533286e-02 | 1.069 | 1 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 8.669642e-02 | 1.062 | 0 | 0 |
| Drug resistance of FLT3 mutants | R-HSA-9702506 | 8.685031e-02 | 1.061 | 0 | 0 |
| FLT3 mutants bind TKIs | R-HSA-9702509 | 8.685031e-02 | 1.061 | 0 | 0 |
| tamatinib-resistant FLT3 mutants | R-HSA-9703009 | 8.685031e-02 | 1.061 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 8.685031e-02 | 1.061 | 0 | 0 |
| ponatinib-resistant FLT3 mutants | R-HSA-9702614 | 8.685031e-02 | 1.061 | 0 | 0 |
| semaxanib-resistant FLT3 mutants | R-HSA-9702577 | 8.685031e-02 | 1.061 | 0 | 0 |
| KW2449-resistant FLT3 mutants | R-HSA-9702569 | 8.685031e-02 | 1.061 | 0 | 0 |
| midostaurin-resistant FLT3 mutants | R-HSA-9702600 | 8.685031e-02 | 1.061 | 0 | 0 |
| sorafenib-resistant FLT3 mutants | R-HSA-9702624 | 8.685031e-02 | 1.061 | 0 | 0 |
| tandutinib-resistant FLT3 mutants | R-HSA-9702636 | 8.685031e-02 | 1.061 | 0 | 0 |
| lestaurtinib-resistant FLT3 mutants | R-HSA-9702596 | 8.685031e-02 | 1.061 | 0 | 0 |
| sunitinib-resistant FLT3 mutants | R-HSA-9702632 | 8.685031e-02 | 1.061 | 0 | 0 |
| crenolanib-resistant FLT3 mutants | R-HSA-9702581 | 8.685031e-02 | 1.061 | 0 | 0 |
| linifanib-resistant FLT3 mutants | R-HSA-9702998 | 8.685031e-02 | 1.061 | 0 | 0 |
| pexidartinib-resistant FLT3 mutants | R-HSA-9702605 | 8.685031e-02 | 1.061 | 0 | 0 |
| gilteritinib-resistant FLT3 mutants | R-HSA-9702590 | 8.685031e-02 | 1.061 | 0 | 0 |
| quizartinib-resistant FLT3 mutants | R-HSA-9702620 | 8.685031e-02 | 1.061 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 8.721222e-02 | 1.059 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 8.727716e-02 | 1.059 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 9.102252e-02 | 1.041 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.210894e-02 | 1.036 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.210894e-02 | 1.036 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 9.293881e-02 | 1.032 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.378072e-02 | 1.028 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 9.703294e-02 | 1.013 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 9.755662e-02 | 1.011 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 9.755662e-02 | 1.011 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 9.755662e-02 | 1.011 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 9.755662e-02 | 1.011 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 9.755662e-02 | 1.011 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 9.755662e-02 | 1.011 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 9.755662e-02 | 1.011 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 9.765478e-02 | 1.010 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.765478e-02 | 1.010 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 9.765478e-02 | 1.010 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 9.834913e-02 | 1.007 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 9.841093e-02 | 1.007 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 9.945623e-02 | 1.002 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 1.008994e-01 | 0.996 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 1.011493e-01 | 0.995 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.018028e-01 | 0.992 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.024661e-01 | 0.989 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.024661e-01 | 0.989 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 1.029004e-01 | 0.988 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 1.031143e-01 | 0.987 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.036121e-01 | 0.985 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 1.041542e-01 | 0.982 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 1.041542e-01 | 0.982 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.041542e-01 | 0.982 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 1.041542e-01 | 0.982 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 1.042541e-01 | 0.982 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 1.088392e-01 | 0.963 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 1.089146e-01 | 0.963 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 1.101301e-01 | 0.958 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 1.110569e-01 | 0.954 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 1.110569e-01 | 0.954 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.113443e-01 | 0.953 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 1.120066e-01 | 0.951 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.126899e-01 | 0.948 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.133955e-01 | 0.945 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 1.144472e-01 | 0.941 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 1.144472e-01 | 0.941 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 1.144472e-01 | 0.941 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 1.145864e-01 | 0.941 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.163661e-01 | 0.934 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 1.163661e-01 | 0.934 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 1.163661e-01 | 0.934 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 1.168471e-01 | 0.932 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 1.181088e-01 | 0.928 | 1 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.181088e-01 | 0.928 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.661623e-01 | 0.779 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.661623e-01 | 0.779 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.661623e-01 | 0.779 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.661623e-01 | 0.779 | 0 | 0 |
| Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) | R-HSA-5619043 | 1.661623e-01 | 0.779 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.661623e-01 | 0.779 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.385900e-01 | 0.622 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 2.385900e-01 | 0.622 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.385900e-01 | 0.622 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.385900e-01 | 0.622 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.385900e-01 | 0.622 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.385900e-01 | 0.622 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 2.385900e-01 | 0.622 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.385900e-01 | 0.622 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.385900e-01 | 0.622 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.338548e-01 | 0.873 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 1.338548e-01 | 0.873 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 1.651559e-01 | 0.782 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 1.651559e-01 | 0.782 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.651559e-01 | 0.782 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 1.975561e-01 | 0.704 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 1.975561e-01 | 0.704 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 1.975561e-01 | 0.704 | 0 | 0 |
| Branched-chain ketoacid dehydrogenase kinase deficiency | R-HSA-9912481 | 1.975561e-01 | 0.704 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 1.575126e-01 | 0.803 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 2.306286e-01 | 0.637 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 2.306286e-01 | 0.637 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 2.306286e-01 | 0.637 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.265301e-01 | 0.898 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 1.795424e-01 | 0.746 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.425290e-01 | 0.846 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.425290e-01 | 0.846 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.023410e-01 | 0.694 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 1.592753e-01 | 0.798 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 1.592753e-01 | 0.798 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 1.592753e-01 | 0.798 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.947329e-01 | 0.711 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 1.603709e-01 | 0.795 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 1.997384e-01 | 0.700 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 1.997384e-01 | 0.700 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 1.326899e-01 | 0.877 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.741552e-01 | 0.759 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 1.519533e-01 | 0.818 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 2.239472e-01 | 0.650 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 2.278411e-01 | 0.642 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.388982e-01 | 0.857 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.479178e-01 | 0.830 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 1.692289e-01 | 0.772 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 1.359232e-01 | 0.867 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 1.984368e-01 | 0.702 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.403684e-01 | 0.853 | 0 | 0 |
| LGI-ADAM interactions | R-HSA-5682910 | 1.364026e-01 | 0.865 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 1.975561e-01 | 0.704 | 1 | 1 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 1.975561e-01 | 0.704 | 0 | 0 |
| PKA activation | R-HSA-163615 | 1.592753e-01 | 0.798 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 1.244090e-01 | 0.905 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.547130e-01 | 0.810 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 2.174408e-01 | 0.663 | 0 | 0 |
| Activation and oligomerization of BAK protein | R-HSA-111452 | 1.661623e-01 | 0.779 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 1.338548e-01 | 0.873 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 1.479178e-01 | 0.830 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 1.732495e-01 | 0.761 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 1.403684e-01 | 0.853 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 1.403684e-01 | 0.853 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 1.947329e-01 | 0.711 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 2.002341e-01 | 0.698 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.506601e-01 | 0.822 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 1.975561e-01 | 0.704 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.692289e-01 | 0.772 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 2.346707e-01 | 0.630 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 1.842511e-01 | 0.735 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 1.539726e-01 | 0.813 | 1 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 1.661623e-01 | 0.779 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.385900e-01 | 0.622 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 2.385900e-01 | 0.622 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 2.306286e-01 | 0.637 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 1.592753e-01 | 0.798 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 2.257621e-01 | 0.646 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 1.732586e-01 | 0.761 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 2.110485e-01 | 0.676 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 1.813087e-01 | 0.742 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 2.371115e-01 | 0.625 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 1.796096e-01 | 0.746 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 2.305948e-01 | 0.637 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 1.479178e-01 | 0.830 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.903041e-01 | 0.721 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 1.651408e-01 | 0.782 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 2.305948e-01 | 0.637 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 1.547130e-01 | 0.810 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 1.523183e-01 | 0.817 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 1.523183e-01 | 0.817 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 1.975561e-01 | 0.704 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.364026e-01 | 0.865 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 2.306286e-01 | 0.637 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.479178e-01 | 0.830 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.233908e-01 | 0.909 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.564538e-01 | 0.806 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 2.306286e-01 | 0.637 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 1.997384e-01 | 0.700 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 1.958495e-01 | 0.708 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.423356e-01 | 0.847 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 2.021813e-01 | 0.694 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 2.164135e-01 | 0.665 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 1.861325e-01 | 0.730 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 2.385900e-01 | 0.622 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.651559e-01 | 0.782 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 1.512561e-01 | 0.820 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 2.142670e-01 | 0.669 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 2.305948e-01 | 0.637 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 2.168795e-01 | 0.664 | 1 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 2.110485e-01 | 0.676 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 1.278175e-01 | 0.893 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 2.257621e-01 | 0.646 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.654731e-01 | 0.781 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 2.319376e-01 | 0.635 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 1.984368e-01 | 0.702 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.985294e-01 | 0.702 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 2.183897e-01 | 0.661 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 1.874574e-01 | 0.727 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 2.319376e-01 | 0.635 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.306286e-01 | 0.637 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 1.298759e-01 | 0.886 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.512561e-01 | 0.820 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.002341e-01 | 0.698 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 1.364026e-01 | 0.865 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 1.410304e-01 | 0.851 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.985294e-01 | 0.702 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 1.338548e-01 | 0.873 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.265301e-01 | 0.898 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 2.023410e-01 | 0.694 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.779003e-01 | 0.750 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.592753e-01 | 0.798 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 2.133013e-01 | 0.671 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 2.239472e-01 | 0.650 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 1.903201e-01 | 0.721 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 2.133013e-01 | 0.671 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 2.406095e-01 | 0.619 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 2.485621e-01 | 0.605 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 2.490359e-01 | 0.604 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 2.495505e-01 | 0.603 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 2.496656e-01 | 0.603 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.496656e-01 | 0.603 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.496656e-01 | 0.603 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 2.496656e-01 | 0.603 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.496656e-01 | 0.603 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 2.496656e-01 | 0.603 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 2.517566e-01 | 0.599 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 2.517566e-01 | 0.599 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.521221e-01 | 0.598 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 2.559081e-01 | 0.592 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 2.581986e-01 | 0.588 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 2.611473e-01 | 0.583 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 2.640126e-01 | 0.578 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.640126e-01 | 0.578 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 2.640126e-01 | 0.578 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 2.640126e-01 | 0.578 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 2.640126e-01 | 0.578 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 2.640126e-01 | 0.578 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 2.641502e-01 | 0.578 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 2.654778e-01 | 0.576 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 2.654778e-01 | 0.576 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 2.654778e-01 | 0.576 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 2.710267e-01 | 0.567 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 2.715013e-01 | 0.566 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 2.715013e-01 | 0.566 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.733534e-01 | 0.563 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 2.733534e-01 | 0.563 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 2.739190e-01 | 0.562 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 2.739190e-01 | 0.562 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 2.739190e-01 | 0.562 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 2.739190e-01 | 0.562 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 2.739190e-01 | 0.562 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 2.739190e-01 | 0.562 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 2.764604e-01 | 0.558 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 2.779799e-01 | 0.556 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 2.826408e-01 | 0.549 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 2.826408e-01 | 0.549 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 2.844444e-01 | 0.546 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.850683e-01 | 0.545 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 2.854519e-01 | 0.544 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 2.887128e-01 | 0.540 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.914983e-01 | 0.535 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 2.935614e-01 | 0.532 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 2.959991e-01 | 0.529 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 2.959991e-01 | 0.529 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 2.959991e-01 | 0.529 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 2.974047e-01 | 0.527 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 2.974047e-01 | 0.527 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 2.974047e-01 | 0.527 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 2.974047e-01 | 0.527 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 2.974047e-01 | 0.527 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.974047e-01 | 0.527 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 2.974047e-01 | 0.527 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 2.974047e-01 | 0.527 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 2.974047e-01 | 0.527 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 2.983980e-01 | 0.525 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 2.983980e-01 | 0.525 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 2.983980e-01 | 0.525 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.038269e-01 | 0.517 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 3.042467e-01 | 0.517 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.047305e-01 | 0.516 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.047305e-01 | 0.516 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 3.047305e-01 | 0.516 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 3.047305e-01 | 0.516 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.047305e-01 | 0.516 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 3.047305e-01 | 0.516 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.047305e-01 | 0.516 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 3.047305e-01 | 0.516 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 3.047305e-01 | 0.516 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 3.066429e-01 | 0.513 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 3.118739e-01 | 0.506 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 3.168172e-01 | 0.499 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 3.175360e-01 | 0.498 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 3.175360e-01 | 0.498 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 3.199248e-01 | 0.495 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 3.229871e-01 | 0.491 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 3.229871e-01 | 0.491 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 3.229871e-01 | 0.491 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 3.292993e-01 | 0.482 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.305520e-01 | 0.481 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 3.305520e-01 | 0.481 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 3.305520e-01 | 0.481 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 3.305520e-01 | 0.481 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.305520e-01 | 0.481 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.305520e-01 | 0.481 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 3.305520e-01 | 0.481 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 3.305520e-01 | 0.481 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 3.305520e-01 | 0.481 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 3.319853e-01 | 0.479 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 3.319853e-01 | 0.479 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 3.319853e-01 | 0.479 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 3.319853e-01 | 0.479 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 3.348409e-01 | 0.475 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.351837e-01 | 0.475 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 3.351837e-01 | 0.475 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 3.357174e-01 | 0.474 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 3.357174e-01 | 0.474 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 3.357174e-01 | 0.474 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 3.377798e-01 | 0.471 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 3.423178e-01 | 0.466 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 3.465463e-01 | 0.460 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 3.475799e-01 | 0.459 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.493291e-01 | 0.457 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 3.505934e-01 | 0.455 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 3.515953e-01 | 0.454 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 3.515953e-01 | 0.454 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 3.515953e-01 | 0.454 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 3.520704e-01 | 0.453 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 3.523502e-01 | 0.453 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 3.523502e-01 | 0.453 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 3.523502e-01 | 0.453 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 3.523502e-01 | 0.453 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 3.560466e-01 | 0.448 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 3.632450e-01 | 0.440 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 3.632450e-01 | 0.440 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 3.632450e-01 | 0.440 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 3.632450e-01 | 0.440 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 3.632450e-01 | 0.440 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 3.632450e-01 | 0.440 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 3.632450e-01 | 0.440 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.632450e-01 | 0.440 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 3.632450e-01 | 0.440 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 3.632450e-01 | 0.440 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 3.632450e-01 | 0.440 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 3.638821e-01 | 0.439 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 3.638821e-01 | 0.439 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 3.639555e-01 | 0.439 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 3.651292e-01 | 0.438 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 3.651292e-01 | 0.438 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 3.651292e-01 | 0.438 | 0 | 0 |
| Defective HPRT1 disrupts guanine and hypoxanthine salvage | R-HSA-9734281 | 3.651292e-01 | 0.438 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.651292e-01 | 0.438 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.651292e-01 | 0.438 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.651292e-01 | 0.438 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 3.675299e-01 | 0.435 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 3.675299e-01 | 0.435 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 3.675299e-01 | 0.435 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 3.720792e-01 | 0.429 | 1 | 1 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 3.720792e-01 | 0.429 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 3.720792e-01 | 0.429 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 3.720792e-01 | 0.429 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 3.720792e-01 | 0.429 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 3.727178e-01 | 0.429 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 3.727178e-01 | 0.429 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 3.727178e-01 | 0.429 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 3.727178e-01 | 0.429 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 3.730487e-01 | 0.428 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 3.784785e-01 | 0.422 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 3.884458e-01 | 0.411 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 3.910635e-01 | 0.408 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 3.930337e-01 | 0.406 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 3.930337e-01 | 0.406 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 3.930337e-01 | 0.406 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 3.930337e-01 | 0.406 | 1 | 0 |
| DARPP-32 events | R-HSA-180024 | 3.930337e-01 | 0.406 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.933845e-01 | 0.405 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 3.953129e-01 | 0.403 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 3.953129e-01 | 0.403 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 3.953129e-01 | 0.403 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 3.953129e-01 | 0.403 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 3.953129e-01 | 0.403 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 3.953129e-01 | 0.403 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 3.953129e-01 | 0.403 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 3.953129e-01 | 0.403 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 3.963968e-01 | 0.402 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 3.963968e-01 | 0.402 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 3.963968e-01 | 0.402 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 3.963968e-01 | 0.402 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 3.963968e-01 | 0.402 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 3.994589e-01 | 0.399 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 4.006366e-01 | 0.397 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.061810e-01 | 0.391 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 4.061810e-01 | 0.391 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 4.077178e-01 | 0.390 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 4.132466e-01 | 0.384 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 4.132466e-01 | 0.384 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 4.154004e-01 | 0.382 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 4.160320e-01 | 0.381 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 4.202843e-01 | 0.376 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 4.202843e-01 | 0.376 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.202843e-01 | 0.376 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 4.202843e-01 | 0.376 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.202843e-01 | 0.376 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 4.202843e-01 | 0.376 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 4.204536e-01 | 0.376 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.204536e-01 | 0.376 | 0 | 0 |
| Immune System | R-HSA-168256 | 4.219068e-01 | 0.375 | 1 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 4.223202e-01 | 0.374 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 4.223202e-01 | 0.374 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 4.223202e-01 | 0.374 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 4.223202e-01 | 0.374 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 4.223202e-01 | 0.374 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.238482e-01 | 0.373 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.238482e-01 | 0.373 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.238482e-01 | 0.373 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 4.238482e-01 | 0.373 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 4.266175e-01 | 0.370 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 4.266175e-01 | 0.370 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 4.266175e-01 | 0.370 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 4.266175e-01 | 0.370 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 4.266175e-01 | 0.370 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 4.266175e-01 | 0.370 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 4.266175e-01 | 0.370 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 4.266175e-01 | 0.370 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 4.266175e-01 | 0.370 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 4.266175e-01 | 0.370 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 4.266175e-01 | 0.370 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 4.333093e-01 | 0.363 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 4.368852e-01 | 0.360 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 4.414151e-01 | 0.355 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 4.441791e-01 | 0.352 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 4.511688e-01 | 0.346 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 4.570496e-01 | 0.340 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 4.570496e-01 | 0.340 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 4.570496e-01 | 0.340 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 4.570496e-01 | 0.340 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.570496e-01 | 0.340 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 4.570496e-01 | 0.340 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 4.628366e-01 | 0.335 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 4.658297e-01 | 0.332 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 4.675111e-01 | 0.330 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 4.675111e-01 | 0.330 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 4.706507e-01 | 0.327 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 4.706507e-01 | 0.327 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 4.706507e-01 | 0.327 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 4.706507e-01 | 0.327 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 4.706507e-01 | 0.327 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.706507e-01 | 0.327 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 4.706507e-01 | 0.327 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 4.706507e-01 | 0.327 | 0 | 0 |
| Hydroxycarboxylic acid-binding receptors | R-HSA-3296197 | 4.706507e-01 | 0.327 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 4.706507e-01 | 0.327 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 4.706507e-01 | 0.327 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 4.706507e-01 | 0.327 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 4.706507e-01 | 0.327 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 4.706507e-01 | 0.327 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 4.706507e-01 | 0.327 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.728124e-01 | 0.325 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 4.728124e-01 | 0.325 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 4.728124e-01 | 0.325 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 4.728124e-01 | 0.325 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 4.761280e-01 | 0.322 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 4.801743e-01 | 0.319 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 4.801743e-01 | 0.319 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 4.843065e-01 | 0.315 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 4.865245e-01 | 0.313 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 4.865245e-01 | 0.313 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 4.865245e-01 | 0.313 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 4.865245e-01 | 0.313 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 4.903954e-01 | 0.309 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 4.903954e-01 | 0.309 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 4.903954e-01 | 0.309 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 4.921759e-01 | 0.308 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 4.944119e-01 | 0.306 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 4.968995e-01 | 0.304 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 5.079524e-01 | 0.294 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 5.127852e-01 | 0.290 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 5.127852e-01 | 0.290 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 5.127852e-01 | 0.290 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 5.149789e-01 | 0.288 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 5.149789e-01 | 0.288 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 5.149789e-01 | 0.288 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 5.149789e-01 | 0.288 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 5.149789e-01 | 0.288 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.166439e-01 | 0.287 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 5.166439e-01 | 0.287 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 5.166439e-01 | 0.287 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.166439e-01 | 0.287 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.166439e-01 | 0.287 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 5.166439e-01 | 0.287 | 0 | 0 |
| Loss-of-function mutations in DBT cause MSUD2 | R-HSA-9865113 | 5.166439e-01 | 0.287 | 0 | 0 |
| Loss-of-function mutations in DLD cause MSUD3/DLDD | R-HSA-9907570 | 5.166439e-01 | 0.287 | 0 | 0 |
| Signaling by MST1 | R-HSA-8852405 | 5.166439e-01 | 0.287 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 5.166439e-01 | 0.287 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 5.166439e-01 | 0.287 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 5.166439e-01 | 0.287 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 5.166439e-01 | 0.287 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 5.166439e-01 | 0.287 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 5.166439e-01 | 0.287 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 5.166439e-01 | 0.287 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 5.166439e-01 | 0.287 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 5.166439e-01 | 0.287 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 5.166439e-01 | 0.287 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 5.166439e-01 | 0.287 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 5.166439e-01 | 0.287 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 5.166439e-01 | 0.287 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 5.166439e-01 | 0.287 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 5.166439e-01 | 0.287 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 5.210034e-01 | 0.283 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 5.267467e-01 | 0.278 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 5.267467e-01 | 0.278 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 5.339317e-01 | 0.273 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 5.346406e-01 | 0.272 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 5.346406e-01 | 0.272 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 5.346406e-01 | 0.272 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 5.346406e-01 | 0.272 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 5.423676e-01 | 0.266 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 5.423676e-01 | 0.266 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 5.423676e-01 | 0.266 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 5.423676e-01 | 0.266 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 5.483279e-01 | 0.261 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 5.484176e-01 | 0.261 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 5.525176e-01 | 0.258 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 5.559286e-01 | 0.255 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 5.559286e-01 | 0.255 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 5.586435e-01 | 0.253 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.586435e-01 | 0.253 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.586435e-01 | 0.253 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.586435e-01 | 0.253 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.586435e-01 | 0.253 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.586435e-01 | 0.253 | 0 | 0 |
| Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD | R-HSA-9865125 | 5.586435e-01 | 0.253 | 0 | 0 |
| H139Hfs13* PPM1K causes a mild variant of MSUD | R-HSA-9912529 | 5.586435e-01 | 0.253 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 5.586435e-01 | 0.253 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 5.586435e-01 | 0.253 | 0 | 0 |
| Lactose synthesis | R-HSA-5653890 | 5.586435e-01 | 0.253 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.586435e-01 | 0.253 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 5.586435e-01 | 0.253 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 5.586435e-01 | 0.253 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.586435e-01 | 0.253 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 5.686611e-01 | 0.245 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 5.686611e-01 | 0.245 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 5.686611e-01 | 0.245 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 5.686611e-01 | 0.245 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 5.719921e-01 | 0.243 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 5.766219e-01 | 0.239 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 5.766219e-01 | 0.239 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 5.766219e-01 | 0.239 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 5.794791e-01 | 0.237 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 5.838916e-01 | 0.234 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 5.838916e-01 | 0.234 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 5.889111e-01 | 0.230 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 5.938428e-01 | 0.226 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 5.938428e-01 | 0.226 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 5.938428e-01 | 0.226 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 5.966990e-01 | 0.224 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 5.969959e-01 | 0.224 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 5.969959e-01 | 0.224 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 5.969959e-01 | 0.224 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 5.969959e-01 | 0.224 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 5.969959e-01 | 0.224 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 5.969959e-01 | 0.224 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 5.969959e-01 | 0.224 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 5.969959e-01 | 0.224 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 5.969959e-01 | 0.224 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 5.969959e-01 | 0.224 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 5.969959e-01 | 0.224 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 5.969959e-01 | 0.224 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 5.969959e-01 | 0.224 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 5.969959e-01 | 0.224 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 5.969959e-01 | 0.224 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 5.969959e-01 | 0.224 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 6.010519e-01 | 0.221 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 6.010519e-01 | 0.221 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 6.058288e-01 | 0.218 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 6.102029e-01 | 0.215 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 6.106805e-01 | 0.214 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 6.139361e-01 | 0.212 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 6.154750e-01 | 0.211 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 6.161433e-01 | 0.210 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 6.177779e-01 | 0.209 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 6.179074e-01 | 0.209 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 6.179074e-01 | 0.209 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 6.179074e-01 | 0.209 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 6.179074e-01 | 0.209 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 6.179074e-01 | 0.209 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 6.241994e-01 | 0.205 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.317678e-01 | 0.199 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.320177e-01 | 0.199 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.320177e-01 | 0.199 | 0 | 0 |
| RSK activation | R-HSA-444257 | 6.320177e-01 | 0.199 | 1 | 1 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.320177e-01 | 0.199 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.320177e-01 | 0.199 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 6.320177e-01 | 0.199 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 6.320177e-01 | 0.199 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 6.320177e-01 | 0.199 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 6.320177e-01 | 0.199 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 6.320177e-01 | 0.199 | 0 | 0 |
| Nucleotide salvage defects | R-HSA-9734207 | 6.320177e-01 | 0.199 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.320177e-01 | 0.199 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 6.320177e-01 | 0.199 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.320177e-01 | 0.199 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 6.325815e-01 | 0.199 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 6.339919e-01 | 0.198 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 6.349432e-01 | 0.197 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 6.349432e-01 | 0.197 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 6.349432e-01 | 0.197 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 6.374446e-01 | 0.196 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 6.408590e-01 | 0.193 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 6.495809e-01 | 0.187 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 6.530909e-01 | 0.185 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 6.530909e-01 | 0.185 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 6.627091e-01 | 0.179 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 6.627091e-01 | 0.179 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.639980e-01 | 0.178 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 6.639980e-01 | 0.178 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.639980e-01 | 0.178 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 6.639980e-01 | 0.178 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.639980e-01 | 0.178 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.639980e-01 | 0.178 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 6.639980e-01 | 0.178 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 6.639980e-01 | 0.178 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 6.639980e-01 | 0.178 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 6.639980e-01 | 0.178 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 6.639980e-01 | 0.178 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 6.705827e-01 | 0.174 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 6.705827e-01 | 0.174 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 6.767568e-01 | 0.170 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 6.801397e-01 | 0.167 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 6.834759e-01 | 0.165 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 6.834759e-01 | 0.165 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 6.834759e-01 | 0.165 | 1 | 1 |
| Basigin interactions | R-HSA-210991 | 6.834759e-01 | 0.165 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 6.874150e-01 | 0.163 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 6.874184e-01 | 0.163 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 6.875593e-01 | 0.163 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 6.898702e-01 | 0.161 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 6.932006e-01 | 0.159 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 6.932006e-01 | 0.159 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 6.932006e-01 | 0.159 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 6.932006e-01 | 0.159 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 6.932006e-01 | 0.159 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 6.932006e-01 | 0.159 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 6.932006e-01 | 0.159 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 6.932006e-01 | 0.159 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 6.932006e-01 | 0.159 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 6.932006e-01 | 0.159 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 6.945648e-01 | 0.158 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 6.988219e-01 | 0.156 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 7.026165e-01 | 0.153 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 7.031826e-01 | 0.153 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 7.031826e-01 | 0.153 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 7.036004e-01 | 0.153 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 7.072225e-01 | 0.150 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 7.085189e-01 | 0.150 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 7.191342e-01 | 0.143 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 7.191342e-01 | 0.143 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 7.191342e-01 | 0.143 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.198668e-01 | 0.143 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 7.198668e-01 | 0.143 | 0 | 0 |
| Propionyl-CoA catabolism | R-HSA-71032 | 7.198668e-01 | 0.143 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 7.198668e-01 | 0.143 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 7.198668e-01 | 0.143 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.198668e-01 | 0.143 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.198668e-01 | 0.143 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.198668e-01 | 0.143 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.218565e-01 | 0.142 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 7.218565e-01 | 0.142 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 7.218565e-01 | 0.142 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.218565e-01 | 0.142 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 7.218565e-01 | 0.142 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 7.218565e-01 | 0.142 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 7.218565e-01 | 0.142 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 7.247101e-01 | 0.140 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 7.268116e-01 | 0.139 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 7.270018e-01 | 0.138 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 7.328941e-01 | 0.135 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 7.386407e-01 | 0.132 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 7.386407e-01 | 0.132 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 7.395283e-01 | 0.131 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 7.395283e-01 | 0.131 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.395283e-01 | 0.131 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 7.395283e-01 | 0.131 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.442167e-01 | 0.128 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 7.442167e-01 | 0.128 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 7.442167e-01 | 0.128 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.442167e-01 | 0.128 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.442167e-01 | 0.128 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 7.442167e-01 | 0.128 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 7.475686e-01 | 0.126 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 7.475686e-01 | 0.126 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 7.475686e-01 | 0.126 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 7.482901e-01 | 0.126 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 7.482901e-01 | 0.126 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 7.482901e-01 | 0.126 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 7.499119e-01 | 0.125 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 7.499749e-01 | 0.125 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 7.544987e-01 | 0.122 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 7.547388e-01 | 0.122 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 7.562310e-01 | 0.121 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.562310e-01 | 0.121 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.562310e-01 | 0.121 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 7.608178e-01 | 0.119 | 0 | 0 |
| Maple Syrup Urine Disease | R-HSA-9865114 | 7.664513e-01 | 0.116 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 7.664513e-01 | 0.116 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 7.664513e-01 | 0.116 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 7.664513e-01 | 0.116 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 7.664513e-01 | 0.116 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 7.664513e-01 | 0.116 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 7.664513e-01 | 0.116 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.664513e-01 | 0.116 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 7.664513e-01 | 0.116 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 7.664513e-01 | 0.116 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.664513e-01 | 0.116 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 7.664513e-01 | 0.116 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 7.664513e-01 | 0.116 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 7.664513e-01 | 0.116 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 7.664513e-01 | 0.116 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 7.664513e-01 | 0.116 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 7.664513e-01 | 0.116 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.664513e-01 | 0.116 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 7.712956e-01 | 0.113 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 7.718223e-01 | 0.112 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 7.719996e-01 | 0.112 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.719996e-01 | 0.112 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 7.719996e-01 | 0.112 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 7.719996e-01 | 0.112 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 7.749704e-01 | 0.111 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 7.801405e-01 | 0.108 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 7.867544e-01 | 0.104 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 7.867544e-01 | 0.104 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 7.867544e-01 | 0.104 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 7.867544e-01 | 0.104 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 7.867544e-01 | 0.104 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 7.867544e-01 | 0.104 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 7.867544e-01 | 0.104 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 7.867544e-01 | 0.104 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 7.867544e-01 | 0.104 | 0 | 0 |
| Diseases of branched-chain amino acid catabolism | R-HSA-9865118 | 7.868702e-01 | 0.104 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 7.868702e-01 | 0.104 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 7.874154e-01 | 0.104 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 7.874154e-01 | 0.104 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 7.874154e-01 | 0.104 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 8.008797e-01 | 0.096 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 8.008797e-01 | 0.096 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 8.035523e-01 | 0.095 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.052935e-01 | 0.094 | 0 | 0 |
| BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV | R-HSA-9859138 | 8.052935e-01 | 0.094 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 8.052935e-01 | 0.094 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.052935e-01 | 0.094 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 8.052935e-01 | 0.094 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.052935e-01 | 0.094 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 8.052935e-01 | 0.094 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.052935e-01 | 0.094 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 8.052935e-01 | 0.094 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 8.052935e-01 | 0.094 | 0 | 0 |
| Disease | R-HSA-1643685 | 8.089984e-01 | 0.092 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 8.172630e-01 | 0.088 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.173293e-01 | 0.088 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 8.187975e-01 | 0.087 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 8.213564e-01 | 0.085 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 8.213564e-01 | 0.085 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.213564e-01 | 0.085 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.222219e-01 | 0.085 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.222219e-01 | 0.085 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 8.222219e-01 | 0.085 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 8.222219e-01 | 0.085 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 8.264646e-01 | 0.083 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 8.264646e-01 | 0.083 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 8.264646e-01 | 0.083 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 8.288890e-01 | 0.082 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 8.315946e-01 | 0.080 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 8.337114e-01 | 0.079 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.349352e-01 | 0.078 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 8.376794e-01 | 0.077 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 8.376794e-01 | 0.077 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 8.376794e-01 | 0.077 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 8.376794e-01 | 0.077 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 8.376794e-01 | 0.077 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 8.376794e-01 | 0.077 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.376794e-01 | 0.077 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 8.376794e-01 | 0.077 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 8.381144e-01 | 0.077 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 8.381144e-01 | 0.077 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 8.381144e-01 | 0.077 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 8.381144e-01 | 0.077 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 8.432412e-01 | 0.074 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.479350e-01 | 0.072 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 8.490130e-01 | 0.071 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.490513e-01 | 0.071 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 8.490513e-01 | 0.071 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 8.505635e-01 | 0.070 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 8.507601e-01 | 0.070 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 8.517938e-01 | 0.070 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 8.517938e-01 | 0.070 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 8.517938e-01 | 0.070 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.517938e-01 | 0.070 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 8.517938e-01 | 0.070 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.517938e-01 | 0.070 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 8.517938e-01 | 0.070 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 8.517938e-01 | 0.070 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 8.517938e-01 | 0.070 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 8.569523e-01 | 0.067 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 8.575750e-01 | 0.067 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 8.575750e-01 | 0.067 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 8.579771e-01 | 0.067 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 8.579771e-01 | 0.067 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 8.593111e-01 | 0.066 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 8.646816e-01 | 0.063 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 8.646816e-01 | 0.063 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.646816e-01 | 0.063 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.646816e-01 | 0.063 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 8.646816e-01 | 0.063 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 8.646816e-01 | 0.063 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 8.646816e-01 | 0.063 | 0 | 0 |
| GDP-fucose biosynthesis | R-HSA-6787639 | 8.646816e-01 | 0.063 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 8.646816e-01 | 0.063 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 8.646816e-01 | 0.063 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 8.676425e-01 | 0.062 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 8.676425e-01 | 0.062 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 8.676425e-01 | 0.062 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 8.689289e-01 | 0.061 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 8.689289e-01 | 0.061 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.717670e-01 | 0.060 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 8.764494e-01 | 0.057 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 8.764494e-01 | 0.057 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 8.764494e-01 | 0.057 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 8.764494e-01 | 0.057 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 8.764494e-01 | 0.057 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 8.779388e-01 | 0.057 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 8.779388e-01 | 0.057 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 8.779388e-01 | 0.057 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 8.779388e-01 | 0.057 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 8.782040e-01 | 0.056 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 8.786652e-01 | 0.056 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 8.786652e-01 | 0.056 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 8.863736e-01 | 0.052 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 8.863736e-01 | 0.052 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 8.863736e-01 | 0.052 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 8.863736e-01 | 0.052 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 8.863736e-01 | 0.052 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 8.863736e-01 | 0.052 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 8.863736e-01 | 0.052 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 8.866269e-01 | 0.052 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 8.871945e-01 | 0.052 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 8.871945e-01 | 0.052 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 8.871945e-01 | 0.052 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 8.871945e-01 | 0.052 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 8.871945e-01 | 0.052 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 8.871945e-01 | 0.052 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 8.871945e-01 | 0.052 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 8.898098e-01 | 0.051 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 8.898098e-01 | 0.051 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 8.942652e-01 | 0.049 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 8.942652e-01 | 0.049 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 8.970056e-01 | 0.047 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 8.970056e-01 | 0.047 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 8.970056e-01 | 0.047 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 8.970056e-01 | 0.047 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 8.970056e-01 | 0.047 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 8.970056e-01 | 0.047 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 8.970056e-01 | 0.047 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 8.970056e-01 | 0.047 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.970056e-01 | 0.047 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.970056e-01 | 0.047 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.016443e-01 | 0.045 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.028115e-01 | 0.044 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.036225e-01 | 0.044 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.036225e-01 | 0.044 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.036225e-01 | 0.044 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.059640e-01 | 0.043 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 9.059640e-01 | 0.043 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 9.059640e-01 | 0.043 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 9.059640e-01 | 0.043 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.059640e-01 | 0.043 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.085403e-01 | 0.042 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.089674e-01 | 0.041 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.095326e-01 | 0.041 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 9.141437e-01 | 0.039 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.141437e-01 | 0.039 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.141437e-01 | 0.039 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.141437e-01 | 0.039 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 9.141437e-01 | 0.039 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 9.141437e-01 | 0.039 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.141437e-01 | 0.039 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 9.149814e-01 | 0.039 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.149814e-01 | 0.039 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 9.209945e-01 | 0.036 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.215667e-01 | 0.035 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.216123e-01 | 0.035 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 9.216123e-01 | 0.035 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 9.216123e-01 | 0.035 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 9.216123e-01 | 0.035 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.216123e-01 | 0.035 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.216123e-01 | 0.035 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.230984e-01 | 0.035 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.248960e-01 | 0.034 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.264284e-01 | 0.033 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.266053e-01 | 0.033 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 9.266053e-01 | 0.033 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 9.266053e-01 | 0.033 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.266053e-01 | 0.033 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 9.266053e-01 | 0.033 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.284316e-01 | 0.032 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.284316e-01 | 0.032 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.284316e-01 | 0.032 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.284316e-01 | 0.032 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.298108e-01 | 0.032 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.318383e-01 | 0.031 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.346581e-01 | 0.029 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.346581e-01 | 0.029 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.346581e-01 | 0.029 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 9.367168e-01 | 0.028 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 9.367168e-01 | 0.028 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 9.367168e-01 | 0.028 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.367168e-01 | 0.028 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.403431e-01 | 0.027 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 9.403431e-01 | 0.027 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 9.403431e-01 | 0.027 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.403431e-01 | 0.027 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.403431e-01 | 0.027 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.403431e-01 | 0.027 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.421654e-01 | 0.026 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.428648e-01 | 0.026 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.428648e-01 | 0.026 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 9.448440e-01 | 0.025 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.453671e-01 | 0.024 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 9.454970e-01 | 0.024 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.455339e-01 | 0.024 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.455339e-01 | 0.024 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 9.455339e-01 | 0.024 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 9.455339e-01 | 0.024 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.455339e-01 | 0.024 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.458663e-01 | 0.024 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.494395e-01 | 0.023 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.494395e-01 | 0.023 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.502733e-01 | 0.022 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.502733e-01 | 0.022 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.502733e-01 | 0.022 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 9.502733e-01 | 0.022 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.526161e-01 | 0.021 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.531089e-01 | 0.021 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 9.546005e-01 | 0.020 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 9.546005e-01 | 0.020 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.546005e-01 | 0.020 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.546005e-01 | 0.020 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.564455e-01 | 0.019 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.565228e-01 | 0.019 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.585515e-01 | 0.018 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.585515e-01 | 0.018 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.585515e-01 | 0.018 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.588741e-01 | 0.018 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.590532e-01 | 0.018 | 1 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.593609e-01 | 0.018 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.621588e-01 | 0.017 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.621588e-01 | 0.017 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.621588e-01 | 0.017 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.624493e-01 | 0.017 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.624493e-01 | 0.017 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.667466e-01 | 0.015 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.684594e-01 | 0.014 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.684594e-01 | 0.014 | 0 | 0 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 9.703110e-01 | 0.013 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.703110e-01 | 0.013 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.712049e-01 | 0.013 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.715851e-01 | 0.013 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.724963e-01 | 0.012 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.733447e-01 | 0.012 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.737116e-01 | 0.012 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.737116e-01 | 0.012 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 9.737116e-01 | 0.012 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.737116e-01 | 0.012 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.737116e-01 | 0.012 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.745509e-01 | 0.011 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.760002e-01 | 0.011 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.760002e-01 | 0.011 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.761878e-01 | 0.010 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.766960e-01 | 0.010 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.780896e-01 | 0.010 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.780896e-01 | 0.010 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.780896e-01 | 0.010 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.799973e-01 | 0.009 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 9.799973e-01 | 0.009 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.799973e-01 | 0.009 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 9.799973e-01 | 0.009 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.799973e-01 | 0.009 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.813443e-01 | 0.008 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.817390e-01 | 0.008 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.817390e-01 | 0.008 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.817390e-01 | 0.008 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.820800e-01 | 0.008 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.827458e-01 | 0.008 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.831181e-01 | 0.007 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.833291e-01 | 0.007 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.833291e-01 | 0.007 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.840447e-01 | 0.007 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 9.840447e-01 | 0.007 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.847809e-01 | 0.007 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.848117e-01 | 0.007 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.852483e-01 | 0.006 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.873163e-01 | 0.006 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.873163e-01 | 0.006 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.876249e-01 | 0.005 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.890027e-01 | 0.005 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.892383e-01 | 0.005 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.894296e-01 | 0.005 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.899006e-01 | 0.004 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.903504e-01 | 0.004 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.903504e-01 | 0.004 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.908167e-01 | 0.004 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.911910e-01 | 0.004 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.911910e-01 | 0.004 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.917625e-01 | 0.004 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.919584e-01 | 0.004 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.919584e-01 | 0.004 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.921680e-01 | 0.003 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.921969e-01 | 0.003 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.938379e-01 | 0.003 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.938379e-01 | 0.003 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.938826e-01 | 0.003 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.944157e-01 | 0.002 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.947517e-01 | 0.002 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.951573e-01 | 0.002 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.960419e-01 | 0.002 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.960419e-01 | 0.002 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.961224e-01 | 0.002 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.961984e-01 | 0.002 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.964939e-01 | 0.002 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.964939e-01 | 0.002 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.965942e-01 | 0.001 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.970580e-01 | 0.001 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 9.972784e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.973077e-01 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.975961e-01 | 0.001 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.977567e-01 | 0.001 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.979523e-01 | 0.001 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.981309e-01 | 0.001 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.983487e-01 | 0.001 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.984427e-01 | 0.001 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.985785e-01 | 0.001 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.985909e-01 | 0.001 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.989033e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.991277e-01 | 0.000 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.991780e-01 | 0.000 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.992497e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.992497e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.992497e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.992606e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.993089e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.993152e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.993598e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.993598e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.995117e-01 | 0.000 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.995264e-01 | 0.000 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.995885e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.996386e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.996990e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.996990e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.997705e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.997711e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.998260e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.998716e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.998793e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.998824e-01 | 0.000 | 1 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.998906e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999329e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999349e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.999403e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999419e-01 | 0.000 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.999419e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999420e-01 | 0.000 | 1 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999499e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999516e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999626e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999694e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999706e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999758e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999784e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999806e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999839e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999866e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999963e-01 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.999970e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999970e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999972e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999975e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999980e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 9.999981e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999985e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999985e-01 | 0.000 | 1 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999986e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999992e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999992e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999993e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999994e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999996e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999997e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.999997e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999998e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999999e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
