QIK

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 S939 Sugiyama POTEF A26C1B VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A6NMY6 T163 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
O00165 S162 Sugiyama HAX1 HS1BP1 GGVLESDARSEsPQPAPDWGsQRPFHRFDDVWPMDPHPRtR
O00231 S298 Sugiyama PSMD11 RYAGRQTEALKCVAQASKNRsLADFEKALTDYRAELRDDPI
O00410 S239 Sugiyama IPO5 KPNB3 RANBP5 PGFLQAVNDSCYQNDDSVLKsLVEIADTVPKYLRPHLEATL
O00468 S738 Sugiyama AGRN AGRIN CGSDGVTYSTECELKKARCEsQRGLYVAAQGACRGPTFAPL
O00571 S71 Sugiyama DDX3X DBX DDX3 GFyDKDSSGWsssKDKDAyssFGsRsDsRGKssFFsDRGsG
O00571 S74 Sugiyama DDX3X DBX DDX3 DKDSSGWsssKDKDAyssFGsRsDsRGKssFFsDRGsGsRG
O14639 S452 Sugiyama ABLIM1 ABLIM KIAA0059 LIMAB1 PtPsAEGyQDVRDRMIHRstsQGsINsPVySRHsYtPTTSR
O14893 S126 Sugiyama GEMIN2 SIP1 QVAQFSTVRQNVNKHRSHWKsQQLDsNVTMPKSEDEEGWKK
O14910 S135 Sugiyama LIN7A MALS1 VELI1 DEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLKRGDQL
O14974 S445 Sugiyama PPP1R12A MBS MYPT1 EEERKDEsPATWRLGLRKtGsyGALAEItASKEGQKEKDTA
O14974 S910 Sugiyama PPP1R12A MBS MYPT1 yETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDST
O15042 S302 Sugiyama U2SURP KIAA0332 SR140 NPQMNEEMLCQEFGRFGPLAsVKIMWPRTDEERARERNCGF
O15067 S215 Sugiyama PFAS KIAA0361 LDSWDLDFYTKRFQELQRNPstVEAFDLAQsNsEHSRHWFF
O15143 S328 Sugiyama ARPC1B ARC41 KAssEGGtAAGAGLDsLHKNsVsQIsVLsGGKAKCSQFCTT
O15226 S618 Sugiyama NKRF ITBA4 NRF VNKIAKRDIEQIIRNYARsEsHtDLtFsRELTNDERKQIHQ
O15523 S71 Sugiyama DDX3Y DBY GFHDKDSSGWSCSKDKDAyssFGsRDSRGKPGYFSERGSGS
O15523 S74 Sugiyama DDX3Y DBY DKDSSGWSCSKDKDAyssFGsRDSRGKPGYFSERGSGSRGR
O43290 S378 Sugiyama SART1 DGLRERELEEIRAKLRLQAQsLSTVGPRLASEYLtPEEMVT
O43707 S763 Sugiyama ACTN4 IARTINEVENQILtRDAKGIsQEQMQEFRASFNHFDKDHGG
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43823 S323 Sugiyama AKAP8 AKAP95 RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE
O43852 S69 Sugiyama CALU HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt
O60220 S94 Sugiyama TIMM8A DDP DDP1 TIM8A SQFILNRLEQTQKSKPVFSEsLsD_________________
O60291 S515 Sugiyama MGRN1 KIAA0544 RNF156 sFItEEVDESssPQQGTRAAsIENVLQDssPEHCGRGPPAD
O60343 S588 Sugiyama TBC1D4 AS160 KIAA0603 tssLENIFSRGANRMRGRLGsVDsFERsNsLASEKDYsPGD
O60664 S175 Sugiyama PLIN3 M6PRBP1 TIP47 RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK
O60664 S179 Sugiyama PLIN3 M6PRBP1 TIP47 QSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGKsEEW
O60664 S217 Sugiyama PLIN3 M6PRBP1 TIP47 EEWADNHLPLTDAELARIAtsLDGFDVAsVQQQRQEQSyFV
O60664 Y95 Sugiyama PLIN3 M6PRBP1 TIP47 VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE
O60716 S230 Sugiyama CTNND1 KIAA0384 PDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRA
O60716 S252 Sugiyama CTNND1 KIAA0384 sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL
O60749 S119 Sugiyama SNX2 TRG9 AVtPVtPttLIAPRIESKsMsAPVIFDRsREEIEEEANGDI
O60814 S39 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
O60927 T75 Sugiyama PPP1R11 HCGV TCTE5 RRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHR
O75122 S313 Sugiyama CLASP2 KIAA0627 YNSLEPSYQKSLQTYLKssGsVAsLPQsDRsssssQEsLNR
O75122 S327 Sugiyama CLASP2 KIAA0627 YLKssGsVAsLPQsDRsssssQEsLNRPFSSKWSTANPSTV
O75347 S60 Sugiyama TBCA MRAEDGENyDIKKQAEILQEsRMMIPDCQRRLEAAyLDLQR
O75390 S453 Sugiyama CS LAQLIWSRALGFPLERPKSMsTEGLMKFVDSKSG_______
O75390 S97 Sugiyama CS GLVyEtsVLDPDEGIRFRGFsIPECQKLLPKAKGGEEPLPE
O75534 S584 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR YSLSKGKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRP
O75581 S1420 PSP LRP6 PRMKGDGETMTNDYVVHGPAsVPLGYVPHPssLSGSLPGMS
O75581 S1490 SIGNOR|PSP LRP6 SSSSssTKGtYFPAILNPPPsPAtERsHYTMEFGYSsNsPs
O75822 S127 Sugiyama EIF3J EIF3S1 PRO0391 VLtPEEQLADKLRLKKLQEEsDLELAKEtFGVNNAVyGIDA
O75822 S202 Sugiyama EIF3J EIF3S1 PRO0391 VLVRDVCISLEIDDLKKITNsLTVLCsEKQKQEKQSKAKKK
O75828 S69 Sugiyama CBR3 SDR21C2 QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLNVLVN
O94776 S54 Sugiyama MTA2 MTA1L1 PID ANGNVEAKVVCLFRRRDIsssLNSLADSNAREFEEESKQPG
O94874 S778 Sugiyama UFL1 KIAA0776 MAXER NLBP RCAD DKEQEDVASTTRKELQELSssIKDLVLKSRKSsVTEE____
O95155 S105 Sugiyama UBE4B HDNB1 KIAA0684 UFD2 LsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsMsQVDVDsG
O95218 S181 Sugiyama ZRANB2 ZIS ZNF265 DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95218 S75 Sugiyama ZRANB2 ZIS ZNF265 tLAEKSRGLFsANDWQCKTCsNVNWARRsECNMCNtPKYAK
O95302 S277 Sugiyama FKBP9 FKBP60 FKBP63 KDSISIENKVVPENCERIsQsGDFLRYHYNGTLLDGTLFDS
O95347 S315 Sugiyama SMC2 CAPE SMC2L1 PRO0324 ILRSLEDALAEAQRVNTKSQsAFDLKKKNLACEESKRKELE
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
P00338 S105 Sugiyama LDHA PIG19 VTANsKLVIItAGARQQEGEsRLNLVQRNVNIFKFIIPNVV
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S237 Sugiyama LDHA PIG19 DLGtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVA
P00338 S319 Sugiyama LDHA PIG19 GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00558 S174 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL
P00558 S175 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN
P00568 S38 Sugiyama AK1 GSGKGTQCEKIVQKyGytHLstGDLLRSEVSSGSARGKKLs
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02545 S295 Sugiyama LMNA LMN1 RQsAERNsNLVGAAHEELQQsRIRIDsLsAQLsQLQKQLAA
P02786 S137 Sugiyama TFRC PAARRLyWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREA
P04040 S515 Sugiyama CAT ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________
P04040 S517 Sugiyama CAT LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________
P04075 S17 Sugiyama ALDOA ALDA ____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst
P04075 S176 Sugiyama ALDOA ALDA EHtPsALAIMENANVLARyAsICQQNGIVPIVEPEILPDGD
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04083 S173 Sugiyama ANXA1 ANX1 LPC1 NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 S321 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04792 S187 Sugiyama HSPB1 HSP27 HSP28 APMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAAK__
P04792 S78 Sugiyama HSPB1 HSP27 HSP28 LPPAAIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVs
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792 T174 Sugiyama HSPB1 HSP27 HSP28 SSsLsPEGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGP
P05023 S369 Sugiyama ATP1A1 KRMARKNCLVKNLEAVETLGstsTICSDKTGTLTQNRMTVA
P05187 S192 Sugiyama ALPP PLAP RVQHAsPAGtyAHtVNRNWysDADVPASARQEGCQDIATQL
P05198 S219 Sugiyama EIF2S1 EIF2A CYGYEGIDAVKEALRAGLNCsTENMPIKINLIAPPRYVMTT
P05362 S43 Sugiyama ICAM1 GPGNAQTSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETP
P05388 S37 Sugiyama RPLP0 IIQLLDDyPKCFIVGADNVGsKQMQQIRMSLRGKAVVLMGK
P05455 S94 Sugiyama SSB KSKAELMEIsEDKTKIRRsPsKPLPEVTDEyKNDVKNRsVY
P05783 S312 Sugiyama KRT18 CYK18 PIG46 AETTLTELRRtVQsLEIDLDsMRNLKAsLENsLREVEARYA
P05783 S399 Sugiyama KRT18 CYK18 PIG46 TYRRLLEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVV
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S410 Sugiyama KRT8 CYK8 TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P05787 S477 Sugiyama KRT8 CYK8 SSRAVVVKKIETRDGKLVsEssDVLPK______________
P05787 T413 Sugiyama KRT8 CYK8 KLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGLtsP
P06733 S27 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06744 T109 Sugiyama GPI KINyTEGRAVLHVALRNRsNtPILVDGKDVMPEVNKVLDKM
P06748 S243 Sugiyama NPM1 NPM KGQEsFKKQEKtPKtPKGPssVEDIKAKMQAsIEKGGsLPK
P07195 S106 Sugiyama LDHB VtANSKIVVVtAGVRQQEGEsRLNLVQRNVNVFKFIIPQIV
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 S320 Sugiyama LDHB GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07237 S439 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB NIVIAKMDstANEVEAVKVHsFPtLKFFPAsADRtVIDyNG
P07237 T442 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB IAKMDstANEVEAVKVHsFPtLKFFPAsADRtVIDyNGERt
P07339 S37 Sugiyama CTSD CPSD PASALVRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQ
P07339 S42 Sugiyama CTSD CPSD VRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQAVPAV
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07355 T163 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
P07384 S474 Sugiyama CAPN1 CANPL1 PIG30 GQPAVHLKRDFFLANAsRARsEQFINLREVSTRFRLPPGEY
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07602 S29 Sugiyama PSAP GLBA SAP1 SLLGAALAGPVLGLKECtRGsAVWCQNVKTASDCGAVKHCL
P07711 S329 Sugiyama CTSL CTSL1 GGyVKMAKDRRNHCGIAsAAsyPtV________________
P07737 S30 Sugiyama PFN1 NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07737 S57 Sugiyama PFN1 GKtFVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDs
P07737 S58 Sugiyama PFN1 KtFVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsL
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 S739 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07814 S747 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 ETSAPFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVREL
P07814 T737 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EKTKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRV
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900 S164 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGT
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S399 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK
P07900 S468 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA GIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQ
P07900 S52 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P07900 S63 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P08195 S252 Sugiyama SLC3A2 MDU1 AFQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDV
P08195 S286 Sugiyama SLC3A2 MDU1 KNQKDDVAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVIL
P08238 S159 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGT
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S391 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK
P08238 S460 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S58 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T94 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSGtKAFM
P08670 S438 Sugiyama VIM FssLNLREtNLDsLPLVDtHsKRTLLIKtVEtRDGQVINEt
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P09651 S360 Sugiyama HNRNPA1 HNRPA1 PyGGGGQyFAKPRNQGGyGGssssssyGsGRRF________
P09651 S368 Sugiyama HNRNPA1 HNRPA1 FAKPRNQGGyGGssssssyGsGRRF________________
P09923 S189 Sugiyama ALPI RVQHAsPAGtyAHtVNRNWysDADMPASARQEGCQDIATQL
P09972 S176 Sugiyama ALDOC ALDC ERTPSALAILENANVLARyAsICQQNGIVPIVEPEILPDGD
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG47 S57 Sugiyama UBB PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0CG48 S57 Sugiyama UBC PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0DPB6 S78 Sugiyama POLR1D MIMKNPEVEFCGyTTTHPSEsKINLRIQTRGTLPAVEPFQR
P10696 S189 Sugiyama ALPG ALPPL ALPPL2 RVQHASPAGAYAHTVNRNWysDADVPASARQEGCQDIATQL
P10768 S189 Sugiyama ESD VSAFAPICNPVLCPWGKKAFsGyLGTDQsKWKAyDAtHLVK
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P11142 S85 Sugiyama HSPA8 HSC70 HSP73 HSPA10 NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11279 S141 Sugiyama LAMP1 NLSDTHLFPNASSKEIKtVEsITDIRADIDKKYRCVSGTQV
P11532 S3623 Sugiyama DMD EAKVNGttVssPstsLQRsDssQPMLLRVVGSQTSDSMGEE
P11586 S318 Sugiyama MTHFD1 MTHFC MTHFD FKPGKWMIQYNNLNLKTPVPsDIDIsRSCKPKPIGKLAREI
P11586 S765 Sugiyama MTHFD1 MTHFC MTHFD ARMFGIPVVVAVNAFKTDTEsELDLIsRLSREHGAFDAVKC
P12004 S172 Sugiyama PCNA sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12268 S416 Sugiyama IMPDH2 IMPD2 APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12814 S744 Sugiyama ACTN1 IARTINEVENQILtRDAKGIsQEQMNEFRAsFNHFDRDHsG
P13010 S318 Sugiyama XRCC5 G22P2 NDDDETEVLKEDIIQGFRyGsDIVPFSKVDEEQMKYKSEGK
P13473 S155 Sugiyama LAMP2 LTVDELLAIRIPLNDLFRCNsLSTLEKNDVVQHYWDVLVQA
P13489 S178 Sugiyama RNH1 PRI RNH SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13489 S225 Sugiyama RNH1 PRI RNH KLEsCGVTSDNCRDLCGIVAsKASLRELALGSNKLGDVGMA
P13637 S359 Sugiyama ATP1A3 KRMARKNCLVKNLEAVETLGstsTICSDKTGTLTQNRMTVA
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S587 Sugiyama EEF2 EF2 CIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKAR
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13674 S149 Sugiyama P4HA1 P4HA GAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDCFE
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13797 S339 Sugiyama PLS3 PRIDINMsGFNETDDLKRAEsMLQQADKLGCRQFVTPADVV
P13797 S540 Sugiyama PLS3 NDDIIVNWVNRTLSEAGKSTsIQSFKDKTISSSLAVVDLID
P13798 S187 Sugiyama APEH D3F15S2 D3S48E DNF15S2 EKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQFV
P13798 S27 Sugiyama APEH D3F15S2 D3S48E DNF15S2 LsEPEEAAALyRGLSRQPALsAACLGPEVtTQyGGQyRTVH
P13798 S303 Sugiyama APEH D3F15S2 D3S48E DNF15S2 YYVDLIGGKCELLSDDsLAVssPRLSPDQCRIVYLQYPSLI
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314 S478 Sugiyama PRKCSH G19P1 DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S100 Sugiyama PKM OIP3 PK2 PK3 PKM2 tHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGPEIR
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S447 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 PKyLNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRK
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P14649 S87 Sugiyama MYL6B MLC1SA EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK
P14866 S544 Sugiyama HNRNPL HNRPL P/OKcl.14 LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH
P15311 S535 Sugiyama EZR VIL2 EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P15880 S190 Sugiyama RPS2 RPS4 WGNKIGKPHTVPCKVTGRCGsVLVRLIPAPRGtGIVsAPVP
P15880 S249 Sugiyama RPS2 RPS4 CtAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQEF
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P15924 S2526 Sugiyama DSP ITITGSDGSTRVVLVDRKtGsQyDIQDAIDKGLVDRKFFDQ
P16070 S71 Sugiyama CD44 LHR MDU2 MDU3 MIC4 DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI
P16152 S69 Sugiyama CBR1 CBR CRN SDR21C1 QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLDVLVN
P16949 S46 Sugiyama STMN1 C1orf215 LAP18 OP18 PRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAEERRKsHEA
P17544 S44 Sugiyama ATF7 ATFA LAVHKHKHEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEV
P17987 S34 Sugiyama TCP1 CCT1 CCTA GEtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTI
P17987 S374 Sugiyama TCP1 CCT1 CCTA ERICDDELILIKNTKARTsAsIILRGANDFMCDEMERSLHD
P18615 S115 Sugiyama NELFE RD RDBP KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs
P18615 S135 Sugiyama NELFE RD RDBP sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18754 S85 Sugiyama RCC1 CHC1 IPEDVVQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsV
P19338 S328 Sugiyama NCL NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK
P19338 S356 Sugiyama NCL LAVVDVRIGMTRKFGyVDFEsAEDLEKALELtGLKVFGNEI
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20674 S104 Sugiyama COX5A PEPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYP
P20674 T105 Sugiyama COX5A EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY
P21108 S10 Sugiyama PRPS1L1 PRPS3 PRPSL ___________MPNIKIFsGssHQDLSQKIADRLGLELGKV
P21333 S2152 Sugiyama FLNA FLN FLN1 VKVTGEGRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQ
P21333 S2158 Sugiyama FLNA FLN FLN1 GRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQDMtAQV
P22059 S190 Sugiyama OSBP OSBP1 QRWVTALELAKAKAVKMLAEsDEsGDEEsVsQtDKTELQNT
P22059 S382 Sugiyama OSBP OSBP1 APEIITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLEETK
P22059 S385 Sugiyama OSBP OSBP1 IITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLEETKKEK
P22059 S386 Sugiyama OSBP OSBP1 ITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLEETKKEKR
P22314 S46 Sugiyama UBA1 A1S9T UBE1 AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA
P22626 S189 Sugiyama HNRNPA2B1 HNRPA2B1 IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF
P22626 S212 Sugiyama HNRNPA2B1 HNRPA2B1 EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23284 S150 Sugiyama PPIB CYPB LKHyGPGWVsMANAGKDTNGsQFFITTVKTAWLDGKHVVFG
P23381 S139 Sugiyama WARS1 IFI53 WARS WRS RIERATGQRPHHFLRRGIFFsHRDMNQVLDAyENKKPFYLY
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23588 S122 Sugiyama EIF4B NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P24534 S174 Sugiyama EEF1B2 EEF1B EF1B DMAKLEECVRsIQADGLVWGssKLVPVGyGIKKLQIQCVVE
P25054 S1389 Sugiyama APC DP2.5 PKsPPEHYVQETPLMFsRCTsVSsLDSFESRSIASSVQSEP
P25054 S2569 Sugiyama APC DP2.5 REHSKHSSSLPRVSTWRRtGsSSSILSASSESSEKAKSEDE
P25054 S960 Sugiyama APC DP2.5 SENSNRTCSMPYAKLEYKRSsNDsLNSVSsSDGYGKRGQMK
P25205 S277 Sugiyama MCM3 RTVLIACNVKQMSKDAQPsFsAEDIAKIKKFSKTRsKDIFD
P25398 S107 Sugiyama RPS12 EWVGLCKIDREGKPRKVVGCsCVVVKDYGKESQAKDVIEEy
P25705 S198 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK
P25705 S76 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV
P25789 S7 Sugiyama PSMA4 HC9 PSC9 ______________MSRRyDsRttIFsPEGRLYQVEYAMEA
P26038 T526 Sugiyama MSN EERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHA
P26232 S667 Sugiyama CTNNA2 CAPR YDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEEKAKIAEQV
P26373 S106 Sugiyama RPL13 BBC1 OK/SW-cl.46 IHKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLIL
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T107 Sugiyama RPL13 BBC1 OK/SW-cl.46 HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF
P26639 S522 Sugiyama TARS1 TARS PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27816 T521 Sugiyama MAP4 GLLKDMsPLsEtEMALGKDVtPPPEtEVVLIKNVCLPPEME
P27986 S154 SIGNOR|EPSD|PSP PIK3R1 GRB1 KLVEAIEKKGLECSTLyRtQssSNLAELRQLLDCDTPSVDL
P27986 S541 EPSD|PSP PIK3R1 GRB1 IQRIMHNyDKLKSRISEIIDsRRRLEEDLKKQAAEyREIDK
P28066 S172 Sugiyama PSMA5 QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK
P28066 S174 Sugiyama PSMA5 FHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEA
P28066 S180 Sugiyama PSMA5 GtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSLI
P28838 S180 Sugiyama LAP3 LAPEP PEPS YEYDDLKQKKKMAVSAKLyGsGDQEAWQKGVLFAsGQNLAR
P28838 S194 Sugiyama LAP3 LAPEP PEPS SAKLyGsGDQEAWQKGVLFAsGQNLARQLMETPANEMTPtR
P29144 S176 Sugiyama TPP2 FDVANNGSsQANKLIKEELQsQVELLNsFEKKYSDPGPVYD
P29401 S105 Sugiyama TKT VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL
P29401 S443 Sugiyama TKT EDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAAN
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 S60 Sugiyama EEF1D EF1D ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P30041 S186 Sugiyama PRDX6 AOP2 KIAA0106 SLQLTAEKRVAtPVDWKDGDsVMVLPtIPEEEAKKLFPKGV
P30048 S199 Sugiyama PRDX3 AOP1 SGLALRGLFIIDPNGVIKHLsVNDLPVGRSVEETLRLVKAF
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 S26 Sugiyama RPL12 DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI
P30622 S195 Sugiyama CLIP1 CYLN1 RSN AAKEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIG
P30622 S197 Sugiyama CLIP1 CYLN1 RSN KEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIGDR
P31153 S247 Sugiyama MAT2A AMS2 MATA2 IKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLtGRKII
P31327 S898 Sugiyama CPS1 LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31327 T45 Sugiyama CPS1 AHQKWKFSRPGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPS
P31327 T900 Sugiyama CPS1 KMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKC
P31943 S23 Sugiyama HNRNPH1 HNRPH HNRPH1 LGTEGGEGFVVKVRGLPWsCsADEVQRFFSDCKIQNGAQGI
P31943 S269 Sugiyama HNRNPH1 HNRPH HNRPH1 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH
P31943 Y266 Sugiyama HNRNPH1 HNRPH HNRPH1 yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948 S16 Sugiyama STIP1 _____MEQVNELKEKGNKALsVGNIDDALQCysEAIKLDPH
P31949 S35 Sugiyama S100A11 MLN70 S100C ESLIAVFQKYAGKDGyNytLsKtEFLsFMNTELAAFTKNQK
P34897 S90 Sugiyama SHMT2 GLELIAsENFCsRAALEALGsCLNNKYSEGYPGKRyyGGAE
P34932 S363 Sugiyama HSPA4 APG2 HSPH2 GATRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAIL
P34932 S414 Sugiyama HSPA4 APG2 HSPH2 ITDVVPYPISLRWNsPAEEGssDCEVFSKNHAAPFSKVLTF
P35221 S668 Sugiyama CTNNA1 FDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEQKAKIAEQV
P35237 S306 Sugiyama SERPINB6 PI6 PTI LRNLGMTDAFELGKADFSGMsQTDLSLSKVVHKSFVEVNEE
P35241 S532 Sugiyama RDX EERVTETQKNERVKKQLQALssELAQARDETKKTQNDVLHA
P35241 S533 Sugiyama RDX ERVTETQKNERVKKQLQALssELAQARDETKKTQNDVLHAE
P35568 S794 GPS6|SIGNOR|iPTMNet|EPSD IRS1 tQRPGEPEEGARHQHLRLSTsSGRLLYAATADDSSSStSSD
P35606 S350 Sugiyama COPB2 MGDAEIKDGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVC
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36578 S365 Sugiyama RPL4 RPL1 RNHKLRVDKAAAAAAALQAKsDEKAAVAGKKPVVGKKGKKA
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 S185 Sugiyama TAGLN2 KIAA0120 CDABP0035 NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______
P37802 S83 Sugiyama TAGLN2 KIAA0120 CDABP0035 CELINALYPEGQAPVKKIQAstMAFKQMEQIsQFLQAAERY
P38117 T241 Sugiyama ETFB FP585 KLSVIsVEDPPQRTAGVKVEtTEDLVAKLKEIGRI______
P38646 S549 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P39748 S255 Sugiyama FEN1 RAD2 CESIRGIGPKRAVDLIQKHKsIEEIVRRLDPNKYPVPENWL
P40227 S246 Sugiyama CCT6A CCT6 CCTZ EDAyILTCNVSLEYEKTEVNsGFFyKSAEEREKLVKAERKF
P40818 S718 Sugiyama USP8 KIAA0055 UBPY AKPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtP
P41091 S282 Sugiyama EIF2S3 EIF2G FDVNKPGCEVDDLKGGVAGGsILKGVLKVGQEIEVRPGIVS
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P43034 S152 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P46013 S1098 Sugiyama MKI67 PAARVTGMKKWPRtPKEEAQsLEDLAGFKELFQtPGPsEEs
P46013 S651 Sugiyama MKI67 ISRsQHDILQMICSKRRsGAsEANLIVAKSWADVVKLGAKQ
P46060 S454 Sugiyama RANGAP1 KIAA1835 SD VstFLAFPsPEKLLRLGPKssVLIAQQTDTSDPEKVVSAFL
P46108 S41 Sugiyama CRK QEAVALLQGQRHGVFLVRDsstsPGDyVLSVSENSRVSHYI
P46459 S298 Sugiyama NSF NAREPKVVNGPEILNKyVGEsEANIRKLFADAEEEQRRLGA
P46459 Y294 Sugiyama NSF GKMLNAREPKVVNGPEILNKyVGEsEANIRKLFADAEEEQR
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46779 S115 Sugiyama RPL28 HMIRKNKYRPDLRMAAIRRAsAILRSQKPVMVKRKRTRPTK
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P47712 S729 Sugiyama PLA2G4A CPLA2 PLA2G4 KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P48637 S276 Sugiyama GSS VDGQEIAVVYFRDGYMPRQYsLQNWEARLLLERSHAAKCPD
P48643 S154 Sugiyama CCT5 CCTE KIAA0098 ADGYEQAARVAIEHLDKISDsVLVDIKDTEPLIQTAKTTLG
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P49005 S75 Sugiyama POLD2 ATRLIQMRPFLENRAQQHWGsGVGVKKLCELQPEEKCCVVG
P49321 S659 Sugiyama NASP IEELKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsst
P49321 S662 Sugiyama NASP LKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsstsGF
P49327 S265 Sugiyama FASN FAS TILNAGTNTDGFKEQGVtFPsGDIQEQLIRSLyQsAGVAPE
P49327 T2215 Sugiyama FASN FAS DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49368 S458 Sugiyama CCT3 CCTG TRIC5 RAVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtW
P49588 S627 Sugiyama AARS1 AARS ATHILNFALRSVLGEADQKGsLVAPDRLRFDFTAKGAMSTQ
P49588 S775 Sugiyama AARS1 AARS VTGAEAQKALRKAESLKKCLsVMEAKVKAQTAPNKDVQREI
P49589 S307 Sugiyama CARS1 CARS VPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKASK
P49790 S607 Sugiyama NUP153 KtPPEDCEGPFRPAEILKEGsVLDILKsPGFAsPKIDSVAA
P49840 Y279 Sugiyama GSK3A LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841 Y216 Sugiyama GSK3B LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49915 S332 Sugiyama GMPS IsDEDRtPRKRISKTLNMttsPEEKRKIIGDTFVKIANEVI
P50395 S396 Sugiyama GDI2 RABGDIB IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD
P50395 T425 Sugiyama GDI2 RABGDIB DAttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED
P50402 T30 Sugiyama EMD EDMD STA tELttLLRRyNIPHGPVVGstRRLyEKKIFEyEtQRRRLsP
P50454 S138 Sugiyama SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 LSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEH
P50454 S139 Sugiyama SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS
P50454 S141 Sugiyama SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI
P50990 S380 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 VVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDDGVNtFK
P50993 S367 Sugiyama ATP1A2 KIAA0778 KRMARKNCLVKNLEAVETLGstsTICSDKTGTLTQNRMTVA
P51116 S504 Sugiyama FXR2 FMR1L2 PTGGRGRGPPPAPRPTSRYNsSsISSVLKDPDsNPYSLLDt
P51532 S1382 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P52298 S13 Sugiyama NCBP2 CBP20 PIG55 ________MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQE
P52594 S359 Sugiyama AGFG1 HRB RAB RIP AGQGGDQGSGFGTTGKAPVGsVVsVPsQssAssDKYAALAE
P52597 S187 Sugiyama HNRNPF HNRPF KALGKHKERIGHRYIEVFKssQEEVRsysDPPLKFMsVQRP
P52597 S54 Sugiyama HNRNPF HNRPF CtIHDGAAGVHFIYTREGRQsGEAFVELGsEDDVKMALKKD
P52597 S63 Sugiyama HNRNPF HNRPF VHFIYTREGRQsGEAFVELGsEDDVKMALKKDRESMGHRyI
P52907 S123 Sugiyama CAPZA1 KEAsDPQPEEADGGLKsWREsCDsALRAYVKDHYSNGFCTV
P52907 S215 Sugiyama CAPZA1 QVHYYEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENA
P53041 S403 Sugiyama PPP5C PPP5 DLLWSDPQPQNGRSISKRGVsCQFGPDVTKAFLEENNLDyI
P53396 S656 Sugiyama ACLY IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR
P53621 S389 Sugiyama COPA SYNPAENAVLLCTRAsNLENstyDLytIPKDADsQNPDAPE
P53999 S118 Sugiyama SUB1 PC4 RPO2TC1 PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P54252 S260 Sugiyama ATXN3 ATX3 MJD MJD1 SCA3 IDMEDEEADLRRAIQLsMQGssRNIsQDMtQtsGTNLTSEE
P55010 S10 Sugiyama EIF5 ___________MSVNVNRsVsDQFyRyKMPRLIAKVEGKGN
P55036 S266 Sugiyama PSMD4 MCB1 AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ
P55036 S358 Sugiyama PSMD4 MCB1 VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55072 S282 Sugiyama VCP HEL-220 HEL-S-70 TGAFFFLINGPEIMSKLAGEsEsNLRKAFEEAEKNAPAIIF
P55072 S765 Sugiyama VCP HEL-220 HEL-S-70 RsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGAGPsQ
P55196 S216 Sugiyama AFDN AF6 MLLT4 SRLAAEVYKDMPETSFTRtIsNPEVVMKRRRQQKLEKRMQE
P55735 S184 Sugiyama SEC13 D3S1231E SEC13A SEC13L1 SEC13R PGsLIDHPSGQKPNYIKRFAsGGCDNLIKLWKEEEDGQWKE
P55769 S122 Sugiyama SNU13 NHP2L1 CSVTIKEGSQLKQQIQsIQQsIERLLV______________
P55795 S269 Sugiyama HNRNPH2 FTP3 HNRPH2 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH
P55795 Y266 Sugiyama HNRNPH2 FTP3 HNRPH2 YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst
P55854 S27 Sugiyama SUMO3 SMT3A SMT3H1 KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P55957 S78 Sugiyama BID QtDGNRssHsRLGRIEADsEsQEDIIRNIARHLAQVGDsMD
P57053 S39 Sugiyama H2BC12L H2BFS H2BS1 VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P57721 S82 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK
P58876 S39 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P60174 S106 Sugiyama TPI1 TPI DCGAtWVVLGHsERRHVFGEsDELIGQKVAHALAEGLGVIA
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60520 S39 Sugiyama GABARAPL2 FLC3A GEF2 AKIRAKYPDRVPVIVEKVSGsQIVDIDKRKYLVPSDITVAQ
P60660 S30 Sugiyama MYL6 AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S239 Sugiyama ACTB VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60891 S10 Sugiyama PRPS1 ___________MPNIKIFsGssHQDLSQKIADRLGLELGKV
P60900 S175 Sugiyama PSMA6 PROS27 DPAGyyCGFKATAAGVKQtEstsFLEKKVKKKFDWTFEQTV
P61081 S175 Sugiyama UBE2M UBC12 NNRRLFEQNVQRSMRGGyIGstyFERCLK____________
P61163 S247 Sugiyama ACTR1A CTRN1 NPQKDETLETEKAQyyLPDGstIEIGPSRFRAPELLFRPDL
P61221 Y594 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 RPRINKLNsIKDVEQKKsGNyFFLDD_______________
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61313 S97 Sugiyama RPL15 EC45 TCBAP0781 KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN
P61326 S106 Sugiyama MAGOH MAGOHA QELEIVIGDEHISFTTSKIGsLIDVNQSKDPEGLRVFYYLV
P61353 S86 Sugiyama RPL27 SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL
P61769 S108 Sugiyama B2M CDABP0092 HDCMA22P TEFTPTEKDEYACRVNHVtLsQPKIVKWDRDM_________
P61916 S29 Sugiyama NPC2 HE1 LLLALSTAAQAEPVQFKDCGsVDGVIKEVNVsPCPtQPCQL
P61956 S28 Sugiyama SUMO2 SMT3B SMT3H2 EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S117 Sugiyama YWHAE CCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAEFAt
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62316 T40 Sugiyama SNRPD2 SNRPD1 EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62736 S241 Sugiyama ACTA2 ACTSA ACTVS GIG46 VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62807 S39 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA
P62906 S6 Sugiyama RPL10A NEDD6 _______________MSSKVsRDtLyEAVREVLHGNQRKRR
P62906 S64 Sugiyama RPL10A NEDD6 QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH
P62937 T157 Sugiyama PPIA CYPA NIVEAMERFGsRNGKTSKKItIADCGQLE____________
P62979 S57 Sugiyama RPS27A UBA80 UBCEP1 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA
P62987 S57 Sugiyama UBA52 UBCEP2 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63165 S61 Sugiyama SUMO1 SMT3C SMT3H3 UBL1 OK/SW-cl.43 TTHLKKLKESYCQRQGVPMNsLRFLFEGQRIADNHtPKELG
P63220 S65 Sugiyama RPS21 RFNGQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF__
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S239 Sugiyama ACTG1 ACTG VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S240 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P68032 S241 Sugiyama ACTC1 ACTC VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68133 S241 Sugiyama ACTA1 ACTA VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P78345 S253 Sugiyama RPP38 DtsFEDLsKPKRKLADGRQAsVtLQPLKIKKLIPNPNKIRK
P78371 S144 Sugiyama CCT2 99D8.1 CCTB QTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIAG
P78371 S150 Sugiyama CCT2 99D8.1 CCTB WREATKAAREALLssAVDHGsDEVKFRQDLMNIAGTTLssK
P78371 S470 Sugiyama CCT2 99D8.1 CCTB IADNAGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAI
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P84098 S12 Sugiyama RPL19 _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
Q00610 S1466 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 PLVKPYLRSVQNHNNKsVNEsLNNLFITEEDyQALRTsIDA
Q00613 S375 Sugiyama HSF1 HSTF1 TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL
Q00688 S34 Sugiyama FKBP3 FKBP25 QLRSEQLPKKDIIKFLQEHGsDsFLAEHKLLGNIKNVAKTA
Q01081 S19 Sugiyama U2AF1 U2AF35 U2AFBP FP793 __MAEyLAsIFGtEKDKVNCsFYFKIGACRHGDRCsRLHNK
Q01082 S1388 Sugiyama SPTBN1 SPTB2 TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy
Q01082 S2048 Sugiyama SPTBN1 SPTB2 VAEAWLLGQEPyLssREIGQsVDEVEKLIKRHEAFEKSAAT
Q01105 S161 Sugiyama SET FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q01581 S404 Sugiyama HMGCS1 HMGCS YSLKVTQDATPGSALDKITAsLCDLKSRLDSRTGVAPDVFA
Q02878 S255 Sugiyama RPL6 TXREB1 tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF
Q04637 S1238 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI RDAVKREAALPPVsPLKAALsEEELEKKsKAIIEEyLHLND
Q04726 S622 Sugiyama TLE3 KIAA1547 VWDLHNQTLVRQFQGHTDGAsCIDISHDGTKLWTGGLDNTV
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q06124 S134 Sugiyama PTPN11 PTP2C SHPTP2 HGHLSGKEAEKLLTEKGKHGsFLVREsQsHPGDFVLSVRTG
Q06210 S261 Sugiyama GFPT1 GFAT GFPT GsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDA
Q06323 S55 Sugiyama PSME1 IFI5111 KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07021 S164 Sugiyama C1QBP GC1QBP HABP1 SF2P32 DGEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVL
Q07021 S213 Sugiyama C1QBP GC1QBP HABP1 SF2P32 VGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDSLDW
Q07021 T165 Sugiyama C1QBP GC1QBP HABP1 SF2P32 GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD
Q08209 S492 Sugiyama PPP3CA CALNA CNA EAKGLDRINERMPPRRDAMPsDANLNsINKALTSETNGTDS
Q08378 S1036 Sugiyama GOLGA3 AKEAADAELGQLRAQGGSSDsSLALHERIQALEAELQAVSH
Q08378 S500 Sugiyama GOLGA3 LERAMTDLQNMLEAKNAsLAssNNDLQVAEEQyQRLMAKVE
Q09028 S146 Sugiyama RBBP4 RBAP48 EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE
Q09666 S220 Sugiyama AHNAK PM227 QsGKtVIRLPsGsGAAsPtGsAVDIRAGAIsAsGPELQGAG
Q10471 S536 Sugiyama GALNT2 NDSRQKWEQIEGNSKLRHVGsNLCLDSRTAKSGGLSVEVCG
Q12888 S1618 Sugiyama TP53BP1 EQYGLGPYEAVtPLtKAADIsLDNLVEGKRKRRsNVssPAt
Q12931 S361 Sugiyama TRAP1 HSP75 HSPC5 SIFYVPDMKPSMFDVSRELGsSVALYSRKVLIQTKATDILP
Q13098 S474 Sugiyama GPS1 COPS1 CSN1 MLRAAVLRNQIHVKsPPREGsQGELtPANsQsRMstNM___
Q13098 S483 Sugiyama GPS1 COPS1 CSN1 QIHVKsPPREGsQGELtPANsQsRMstNM____________
Q13136 S668 Sugiyama PPFIA1 LIP1 EEKENTEQRAEEIESRVGsGsLDNLGRFRSMssIPPYPAss
Q13136 T572 Sugiyama PPFIA1 LIP1 LRRPQKGRLAALRDEPSKVQtLNEQDWERAQQASVLANVAQ
Q13243 S153 Sugiyama SRSF5 HRS SFRS5 SRP40 EVTFADAHRPKLNEGVVEFAsYGDLKNAIEKLSGKEINGRK
Q13263 S473 Sugiyama TRIM28 KAP1 RNF96 TIF1B sGDDPyssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERL
Q13283 S250 Sugiyama G3BP1 G3BP sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI
Q13283 S253 Sugiyama G3BP1 G3BP PAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPH
Q13283 S362 Sugiyama G3BP1 G3BP LFIGNLPHEVDKSELKDFFQsyGNVVELRINsGGKLPNFGF
Q13283 S67 Sugiyama G3BP1 G3BP sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN
Q13347 S217 Sugiyama EIF3I EIF3S2 TRIP1 sRDMtMFVtASKDNTAKLFDsttLEHQKTFRTERPVNSAAL
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13573 S182 Sugiyama SNW1 SKIIP SKIP AMPVRAADKLAPAQyIRytPsQQGVAFNsGAKQRVIRMVEM
Q13586 S512 Sugiyama STIM1 GOK SPSLQSSVRQRLTEPQHGLGsQRDLtHsDsEssLHMSDRQR
Q13615 S906 Sugiyama MTMR3 KIAA0371 ZFYVE10 ETSLVERPQVGSVVHRTsLGstLsLTRsPCALPLAECKEGL
Q13625 S480 Sugiyama TP53BP2 ASPP2 BBP FDAVDQSNAPPSFGTLRKNQssEDILRDAQVANKNVAKVPP
Q13733 S377 Sugiyama ATP1A4 ATP1AL2 KRMARKNCLVKNLEAVETLGstsTICSDKTGTLTQNRMTVA
Q13765 S186 Sugiyama NACA HSD48 sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q14008 S1873 Sugiyama CKAP5 KIAA0097 LyEyKKKYsDADIEPFLKNSsQFFQSYVERGLRVIEMEREG
Q14103 S271 Sugiyama HNRNPD AUF1 HNRPD KCEIKVAMSKEQyQQQQQWGsRGGFAGRARGRGGGPSQNWN
Q14151 S827 Sugiyama SAFB2 KIAA0138 HGGPPERHGRDsRDGWGGyGsDKRLsEGRGLPPPPRGGRDW
Q14151 Y825 Sugiyama SAFB2 KIAA0138 HGHGGPPERHGRDsRDGWGGyGsDKRLsEGRGLPPPPRGGR
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S1258 Sugiyama EIF3A EIF3S10 KIAA0139 RFRRPRDEGGWRRGPAEEsssWRDssRRDDRDRDDRRRERD
Q14152 S492 Sugiyama EIF3A EIF3S10 KIAA0139 VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14157 S356 Sugiyama UBAP2L KIAA0144 NICE4 HsMVsMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLA
Q14157 S360 Sugiyama UBAP2L KIAA0144 NICE4 sMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLAAQHS
Q14192 S257 Sugiyama FHL2 DRAL SLIM3 IsFEERQWHNDCFNCKKCsLsLVGRGFLTERDDILCPDCGK
Q14204 S3257 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 NDKLKKMVKDQQEAEKKKVMsQEIQEQLHKQQEVIADKQMS
Q14204 S4162 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 GRIFVFEPPPGVKANMLRTFssIPVSRICKSPNERARLYFL
Q14432 S273 Sugiyama PDE3A RYVEQILPQSAEAAPREHLGsQLIAGTKEDIPVFKRRRRss
Q14432 S312 Sugiyama PDE3A sssVVsAEMSGCSSKSHRRtsLPCIPREQLMGHSEWDHKRG
Q14432 T311 Sugiyama PDE3A RsssVVsAEMSGCSSKSHRRtsLPCIPREQLMGHSEWDHKR
Q14444 S120 Sugiyama CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 QEVtNNLEFAKELQRsFMALsQDIQKTIKKTARREQLMREE
Q14498 S334 Sugiyama RBM39 HCC1 RNPC2 FELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtT
Q14568 S164 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGT
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 S52 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q14677 S163 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 DRLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSK
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14677 S210 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 KNKSAFPFSDKLGELsDKIGstIDDtIsKFRRKDREDsPER
Q14980 S1181 Sugiyama NUMA1 NMP22 NUMA DsALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQD
Q14C86 S902 Sugiyama GAPVD1 GAPEX5 KIAA1521 RAP6 AEMEAFKQRHSYPERLVRsRssDIVSSVRRPMSDPSWNRRP
Q14C86 S903 Sugiyama GAPVD1 GAPEX5 KIAA1521 RAP6 EMEAFKQRHSYPERLVRsRssDIVSSVRRPMSDPSWNRRPG
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15021 S1333 Sugiyama NCAPD2 CAPD2 CNAP1 KIAA0159 APsAKKPSTGSRyQPLAstAsDNDFVtPEPRRTTRRHPNTQ
Q15021 T1331 Sugiyama NCAPD2 CAPD2 CNAP1 KIAA0159 QRAPsAKKPSTGSRyQPLAstAsDNDFVtPEPRRTTRRHPN
Q15029 S948 Sugiyama EFTUD2 KIAA0031 SNRP116 HLAREFMIKTRRRKGLsEDVsIsKFFDDPMLLELAKQDVVL
Q15029 S950 Sugiyama EFTUD2 KIAA0031 SNRP116 AREFMIKTRRRKGLsEDVsIsKFFDDPMLLELAKQDVVLNY
Q15078 S91 SIGNOR|EPSD|PSP CDK5R1 CDK5R NCK5A NSSYQNNITHLNNENLKKSLsCANLSTFAQPPPAQPPAPPA
Q15084 S377 Sugiyama PDIA6 ERP5 P5 TXNDC7 PAMAAINARKMKFALLKGsFsEQGINEFLRELsFGRGstAP
Q15121 S116 Sugiyama PEA15 DtKLtRIPsAKKYKDIIRQPsEEEIIKLAPPPKKA______
Q15154 S580 Sugiyama PCM1 VNSHSNAQCVSNNRDGRTVNsNCEINNRsAANIRALNMPPS
Q15154 S588 Sugiyama PCM1 CVSNNRDGRTVNsNCEINNRsAANIRALNMPPSLDCRYNRE
Q15185 S113 Sugiyama PTGES3 P23 TEBP RAKLNWLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGD
Q15185 S82 Sugiyama PTGES3 P23 TEBP NDsKHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVD
Q15185 S85 Sugiyama PTGES3 P23 TEBP KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN
Q15276 S407 Sugiyama RABEP1 RAB5EP RABPT5 RABPT5A GDPFSKSDNDMFKDGLRRAQstDsLGtsGsLQSKALGYNYK
Q15293 S80 Sugiyama RCN1 RCN HEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGDGFVt
Q15365 S50 Sugiyama PCBP1 GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK
Q15366 S50 Sugiyama PCBP2 GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK
Q15424 S803 Sugiyama SAFB HAP HET SAFB1 RHGGPERHGRDsRDGWGGyGsDKRMsEGRGLPPPPRRDWGD
Q15424 Y801 Sugiyama SAFB HAP HET SAFB1 PERHGGPERHGRDsRDGWGGyGsDKRMsEGRGLPPPPRRDW
Q15642 S296 Sugiyama TRIP10 CIP4 STOT STP FARPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRS
Q15746 S343 PSP MYLK MLCK MLCK1 MYLK1 ESCKDSPRTAPQtPVLQKTSsSITLQAARVQPEPRAPGLGV
Q15751 S1512 Sugiyama HERC1 LtAESRLVHtsPNYRLIKsRsEsDLsQPEsDEEGYALsGRR
Q15751 S1514 Sugiyama HERC1 AESRLVHtsPNYRLIKsRsEsDLsQPEsDEEGYALsGRRNV
Q15818 S91 Sugiyama NPTX1 TILSQKETIRELTAKLGRCEsQsTLDPGAGEARAGGGRKQP
Q16513 S583 Sugiyama PKN2 PRK2 PRKCL2 VTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQDs
Q16576 S145 Sugiyama RBBP7 RBAP46 EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE
Q16658 S237 Sugiyama FSCN1 FAN1 HSN SNL RsGKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALE
Q16719 S443 Sugiyama KYNU VVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAET
Q16836 S196 Sugiyama HADH HAD HAD1 HADHSC SCHAD PVMKLVEVIKTPMTSQKTFEsLVDFSKALGKHPVSCKDTPG
Q2VIR3 S282 Sugiyama EIF2S3B FDVNKPGCEVDDLKGGVAGGsILKGVLKVGQETEVRPGIVS
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3V6T2 S1702 Sugiyama CCDC88A APE GRDN KIAA1212 TLQQFLEEsNKLTSVQIKsssQENLLDEVMKSLsVssDFLG
Q53EL6 S46 Sugiyama PDCD4 H731 GDEENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKN
Q53ET0 S171 GPS6|SIGNOR|iPTMNet|EPSD CRTC2 TORC2 NFPAEKGQLFRLPSALNRtssDsALHtsVMNPsPQDtYPGP
Q562R1 S240 Sugiyama ACTBL2 VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q58FF6 S34 Sugiyama HSP90AB4P IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S58 Sugiyama HSP90AB3P HSP90BC IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 S58 Sugiyama HSP90AB2P HSP90BB IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q5JSH3 S565 Sugiyama WDR44 RPH11 DYFNNMRMKYNtEGRVsPsPsQEsLsssKsDTDtGVCsGtD
Q5JVF3 S24 Sugiyama PCID2 HT004 ITINQYLQQVYEAIDSRDGAsCAELVSFKHPHVANPRLQMA
Q5QNW6 S39 Sugiyama H2BC18 HIST2H2BF VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q5SSJ5 S227 Sugiyama HP1BP3 LKRELNRGVIKQVKGKGAsGsFVVVQKSRKTPQKSRNRKNR
Q5T035 S66 Sugiyama FAM120A2P C9orf129 LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERSLPI
Q5VT25 S222 Sugiyama CDC42BPA KIAA0451 IKPDNILMDMNGHIRLADFGsCLKLMEDGTVQsSVAVGtPD
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6EEV6 S28 Sugiyama SUMO4 SMT3H4 EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC
Q6GYQ0 S797 Sugiyama RALGAPA1 GARNL1 KIAA0884 TULIP1 EtGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDM
Q6NVY1 S381 Sugiyama HIBCH PADLKEVtEEDLNNHFKSLGsSDLKF_______________
Q6P996 S721 Sugiyama PDXDC1 KIAA0251 LPGQKPFKRsLRGsDALsEtssVsHIEDLEKVERLssGPEQ
Q6PID6 S19 Sugiyama TTC33 __MASFGWKRKIGEKVSKVTsQQFEAEAADEKDVVDNDEGN
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 S939 Sugiyama POTEE A26C1A POTE2 VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6UUV9 S151 GPS6|EPSD CRTC1 KIAA0616 MECT1 TORC1 WAMTP1 CPYGTMYLsPPADTSWRRtNsDsALHQstMtPtQPEsFssG
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z417 S652 Sugiyama NUFIP2 KIAA1321 PIG1 NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI
Q7Z417 S655 Sugiyama NUFIP2 KIAA1321 PIG1 LGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsIWNL
Q7Z417 S671 Sugiyama NUFIP2 KIAA1321 PIG1 DsWGsFDLRAAIVYHTKEMEsIWNLQKQDPKRIItyNEAMD
Q7Z460 S545 Sugiyama CLASP1 KIAA0622 MAST1 yHTLESSyQKALQSHLKNSDsIVsLPQsDRsssssQEsLNR
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86VQ1 S226 Sugiyama GLCCI1 sCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQRSKQ
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IYB3 T239 Sugiyama SRRM1 SRM160 KtPELPEPsVKVKEPsVQEAtstsDILKVPKPEPIPEPKEP
Q8IZP0 S22 Sugiyama ABI1 SSH3BP1 AELQMLLEEEIPSGKRALIEsyQNLTRVADyCENNyIQATD
Q8N684 T203 Sugiyama CPSF7 GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP
Q8N806 S265 Sugiyama UBR7 C14orf130 KDDVREVKVEQNsEPCAGsssEsDLQtVFKNESLNAESKSG
Q8NBJ7 S256 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG
Q8NHW5 S37 Sugiyama RPLP0P6 IIQLLDDyPKCFIVGADNVGsKQMQQIRMSLRGKVVVLMGK
Q8TDD1 S581 Sugiyama DDX54 RLVDSIKNYRSRATIFEINAsSRDLCsQVMRAKRQKDRKAI
Q8WU68 S19 Sugiyama U2AF1L4 U2AF1-RS3 U2AF1L3 __MAEyLAsIFGtEKDKVNCsFYFKIGVCRHGDRCSRLHNK
Q8WU90 S351 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 DIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLsEAs
Q8WUF5 S102 Sugiyama PPP1R13L IASPP NKIP1 PPP1R13BL RAI RGsPRKAATDGADtPFGRsEsAPtLHPysPLsPKGRPssPR
Q8WWH5 S268 Sugiyama TRUB1 PUS4 ECGGGFYIRSLVSDIGKELSsCANVLELTRTKQGPFTLEEH
Q8WWI1 S1510 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 RsAsVNKEPVSLPGIMRRGEsLDNLDsPRSNSWRQPPWLNQ
Q8WWI1 S704 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 KKRLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEM
Q8WXH0 S2781 Sugiyama SYNE2 KIAA1011 NUA ILSQIRKCKVTHDGILARQQsVEsLAEEVKDKVPSLTTYEG
Q92499 S541 Sugiyama DDX1 NLEQYFIQQGGGPDKKGHQFsCVCLHGDRKPHERKQNLERF
Q92526 S246 Sugiyama CCT6B EDAFILICNVSLEYEKTEVNsGFFyKTAEEKEKLVKAERKF
Q92609 S541 Sugiyama TBC1D5 KIAA0210 EsMPVQLNKGLSSKNIsssPsVEsLPGGREFtGsPPssAtK
Q92626 S1300 Sugiyama PXDN KIAA0230 MG50 PRG2 PXD01 VPO VPO1 NITRVQSDVFRVAEFPHGyGsCDEIPRVDLRVWQDCCEDCR
Q92974 S711 Sugiyama ARHGEF2 KIAA0651 LFP40 sGGNtsPGVtANGEARTFNGsIELCRADsDssQRDRNGNQL
Q93045 S80 Sugiyama STMN2 SCG10 SCGN10 PPsPISEAPRTLAsPKKKDLsLEEIQKKLEAAEERRKsQEA
Q93079 S39 Sugiyama H2BC9 H2BFJ HIST1H2BH VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q96A72 S108 Sugiyama MAGOHB MAGOH2 QELEIVIGDEHISFTTSKIGsLIDVNQSKDPEGLRVFYYLV
Q96AC1 S255 Sugiyama FERMT2 KIND2 MIG2 PLEKHC1 KMFKPQALLDKAKINQGWLDsSRSLMEQDVKENEALLLRFK
Q96AE4 S270 Sugiyama FUBP1 MVLELIRDQGGFREVRNEyGsRIGGNEGIDVPIPRFAVGIV
Q96D15 S98 Sugiyama RCN3 UNQ239/PRO272 ARLGRIVDRMDRAGDGDGWVsLAELRAWIAHTQQRHIRDsV
Q96EP5 S208 Sugiyama DAZAP1 AEPRDsKsQAPGQPGAsQWGsRVVPNAANGWAGQPPPTWQQ
Q96ES7 S31 Sugiyama SGF29 CCDC101 AELLTELHQLIKQTQEERsRsEHNLVNIQKTHERMQTENKI
Q96EY7 S651 Sugiyama PTCD3 MRPS39 TRG15 VELASAFSLPICEGLTQRVMsDFAINQEQKEALsNLtALts
Q96HP0 S190 Sugiyama DOCK6 KIAA1395 NDSRRGsGsPEDtPRssGASsIFDLRNLAADSLLPSLLERA
Q96IR7 S360 Sugiyama HPDL GLOXD1 LIQRQGATGFGQGNIRALWQsVQEQsARSQEA_________
Q96L92 S51 Sugiyama SNX27 KIAA0488 My014 AGNGGGGGGGPRVVRIVKsEsGYGFNVRGQVsEGGQLRSIN
Q96N67 S1438 Sugiyama DOCK7 KIAA1771 LGTYTIAsPPERsPsGsAFGsQENLRWRKDMTHWRQNTEKL
Q96PK6 S520 Sugiyama RBM14 SIP AAAAYGAQPSATLAAPYRtQssAsLAAsYAAQQHPQAAASY
Q96PK6 S620 Sugiyama RBM14 SIP KRYGSDRRLAELsDYRRLsEsQLsFRRsPtKSSLDYRRLPD
Q96S59 S181 Sugiyama RANBP9 RANBPM QEtPLPRSWsPKDKFsYIGLsQNNLRVHYKGHGKTPKDAAS
Q96S59 S613 Sugiyama RANBP9 RANBPM DCDtEMEVDSsQLRRQLCGGsQAAIERMIHFGRELQAMSEQ
Q99439 S217 Sugiyama CNN2 ILPPMDHSTISLQMGTNKCAsQVGMTAPGTRRHIyDTKLGT
Q99613 S754 Sugiyama EIF3C EIF3S8 REHVVAASKAMKMGDWKTCHsFIINEKMNGKVWDLFPEADK
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99627 S157 Sugiyama COPS8 CSN8 VGLPVEEAVKGILEQGWQADstTRMVLPRKPVAGALDVsFN
Q99877 S39 Sugiyama H2BC15 H2BFD HIST1H2BN VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99879 S39 Sugiyama H2BC14 H2BFE HIST1H2BM INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99880 S39 Sugiyama H2BC13 H2BFC HIST1H2BL VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q9BRG2 S180 Sugiyama SH2D3A NSP1 UNQ175/PRO201 EDPAGMEASTMPISALPRtssDPVLLKAPAPLGTVADsLRA
Q9BRS2 T509 Sugiyama RIOK1 RIO1 QVEERtCsDsEDIGssECsDtDSEEQGDHARPKKHTTDPDI
Q9BT78 S297 Sugiyama COPS4 CSN4 QLQEFAAMLMPHQKATTADGssILDRAVIEHNLLSASKLYN
Q9BT78 S340 Sugiyama COPS4 CSN4 TFEELGALLEIPAAKAEKIAsQMITEGRMNGFIDQIDGIVH
Q9BV73 S2392 SIGNOR|EPSD|PSP CEP250 CEP2 CNAP1 DYITRSAQTSRELAGLHHsLsHsLLAVAQAPEATVLEAETR
Q9BV73 S2394 SIGNOR|EPSD|PSP CEP250 CEP2 CNAP1 ITRSAQTSRELAGLHHsLsHsLLAVAQAPEATVLEAETRRL
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BX40 S165 Sugiyama LSM14B C20orf40 FAM61B RAP55B GFPSIPVGKsPMVEQAVQtGsADNLNAKKLLPGKGTTGTQL
Q9BX40 T163 Sugiyama LSM14B C20orf40 FAM61B RAP55B GAGFPSIPVGKsPMVEQAVQtGsADNLNAKKLLPGKGTTGT
Q9BYX7 S239 Sugiyama POTEKP ACTBL3 FKSG30 VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BZ72 S644 Sugiyama PITPNM2 KIAA1457 NIR3 SGGGGSSGGSSLESSRHLsRsNVDIPRSNGTEDPKRQLPRK
Q9C0C2 S1229 Sugiyama TNKS1BP1 KIAA1741 TAB182 LESGGSEEPGGIGVGEKDWtsDVNVKSKDLAEVGEGGGHsQ
Q9C0C9 S115 Sugiyama UBE2O KIAA1734 GRGssGCSEAGGAGHEEGRAsPLRRGYVRVQWYPEGVKQHV
Q9H0H5 S257 Sugiyama RACGAP1 KIAA1478 MGCRACGAP ETVPYWtRSRRKtGtLQPWNsDstLNSRQLEPRTETDsVGt
Q9H0K1 S342 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 SYNHFAAIYFLLVERLKSHRssFPVEQRLDGRQRRPstIAE
Q9H0K1 S343 SIGNOR|EPSD|PSP|Sugiyama SIK2 KIAA0781 QIK SNF1LK2 YNHFAAIYFLLVERLKSHRssFPVEQRLDGRQRRPstIAEQ
Q9H0K1 S358 EPSD|PSP|Sugiyama SIK2 KIAA0781 QIK SNF1LK2 KSHRssFPVEQRLDGRQRRPstIAEQtVAKAQtVGLPVTMH
Q9H0K1 S379 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 tIAEQtVAKAQtVGLPVTMHsPNMRLLRSALLPQASNVEAF
Q9H0K1 S486 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 PAHAFEAFQSTRSGQRRHtLsEVtNQLVVMPGAGKIFSMND
Q9H0K1 S534 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 DSEYDMGSVQRDLNFLEDNPsLKDIMLANQPsPRMTSPFIS
Q9H0K1 S545 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 DLNFLEDNPsLKDIMLANQPsPRMTSPFISLRPTNPAMQAL
Q9H0K1 S576 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 RPTNPAMQALSSQKREVHNRsPVsFREGRRAsDtsLtQGIV
Q9H0K1 S579 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 NPAMQALSSQKREVHNRsPVsFREGRRAsDtsLtQGIVAFR
Q9H0K1 S587 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 SQKREVHNRsPVsFREGRRAsDtsLtQGIVAFRQHLQNLAR
Q9H0K1 S590 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 REVHNRsPVsFREGRRAsDtsLtQGIVAFRQHLQNLARTKG
Q9H0K1 S674 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 QQESVSTLPASVHPQLSPRQsLEtQYLQHRLQKPSLLSKAQ
Q9H0K1 S707 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 PSLLSKAQNtCQLYCKEPPRsLEQQLQEHRLQQKRLFLQKQ
Q9H0K1 S90 EPSD|PSP SIK2 KIAA0781 QIK SNF1LK2 IMKMLDHPHIIKLYQVMETKsMLYLVTEYAKNGEIFDYLAN
Q9H0K1 T359 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 SHRssFPVEQRLDGRQRRPstIAEQtVAKAQtVGLPVTMHs
Q9H0K1 T364 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 FPVEQRLDGRQRRPstIAEQtVAKAQtVGLPVTMHsPNMRL
Q9H0K1 T370 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 LDGRQRRPstIAEQtVAKAQtVGLPVTMHsPNMRLLRSALL
Q9H0K1 T484 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 EDPAHAFEAFQSTRSGQRRHtLsEVtNQLVVMPGAGKIFSM
Q9H0K1 T489 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 AFEAFQSTRSGQRRHtLsEVtNQLVVMPGAGKIFSMNDSPS
Q9H0K1 T589 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 KREVHNRsPVsFREGRRAsDtsLtQGIVAFRQHLQNLARTK
Q9H0K1 T592 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 VHNRsPVsFREGRRAsDtsLtQGIVAFRQHLQNLARTKGIL
Q9H0K1 T677 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 SVSTLPASVHPQLSPRQsLEtQYLQHRLQKPSLLSKAQNtC
Q9H0K1 T696 Sugiyama SIK2 KIAA0781 QIK SNF1LK2 EtQYLQHRLQKPSLLSKAQNtCQLYCKEPPRsLEQQLQEHR
Q9H173 S128 Sugiyama SIL1 UNQ545/PRO836 DKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEMESsK
Q9H299 S14 Sugiyama SH3BGRL3 P1725 _______MSGLRVYSTSVTGsREIKSQQsEVTRILDGKRIQ
Q9H2G2 S341 Sugiyama SLK KIAA0204 STK2 EDEEEEtENsLPIPAsKRAssDLsIAssEEDKLsQNACILE
Q9H2J4 S151 Sugiyama PDCL3 PhLP2A VIAF1 NQHLSGLARKFPDVKFIKAIsTTCIPNYPDRNLPTIFVYLE
Q9H3N1 S228 Sugiyama TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 PSKRRRPQPYPYPSKKLLsEsAQPLKKVEEEQEADEEDVsE
Q9H501 S77 Sugiyama ESF1 ABTAP C20orf6 HDCMC28P GRPISHSTTEDLKRFyDLsDsDsNLsGEDSKALSQKKIKKK
Q9H6H4 S152 Sugiyama REEP4 C8orf20 PP432 AAVQAATKSQGALAGRLRsFsMQDLRSISDAPAPAyHDPLy
Q9H788 S315 Sugiyama SH2D4A PPP1R38 SH2A LNSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRA
Q9H7D7 S121 Sugiyama WDR26 CDW2 MIP2 PRO0852 ASSSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLN
Q9H7E9 T40 Sugiyama C8orf33 PCAsRGARLPGPVsSARNPstVCLCPEQPTCSNADSRAHPL
Q9HA77 T546 Sugiyama CARS2 OK/SW-cl.10 CDTLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG__
Q9HA77 T547 Sugiyama CARS2 OK/SW-cl.10 DTLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG___
Q9HAP6 S120 Sugiyama LIN7B MALS2 VELI2 UNQ3116/PRO10200 DEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLKRGDQL
Q9HCN4 S301 Sugiyama GPN1 MBDIN RPAP4 XAB1 HUSSY-23 ANAESQQQREQLERLRKDMGsVALDAGtAKDsLsPVLHPsD
Q9HCN8 S40 Sugiyama SDF2L1 UNQ1941/PRO4424 ALLVPGGGAAKTGAELVTCGsVLKLLNTHHRVRLHSHDIKY
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NRY5 S209 Sugiyama FAM114A2 C5orf3 AEGDPGFKRTKGLMNRNATLsQVLREAKEKEEIRTSNEVTV
Q9NRZ9 T166 Sugiyama HELLS PASG SMARCA6 Nbla10143 EILSVAKKNKKENEDENssstNLCVEDLQKNKDSNSIIKDR
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NTX5 S113 Sugiyama ECHDC1 LENWTEGKGLIVRGAKNTFSsGSDLNAVKSLGTPEDGMAVC
Q9NUP9 S120 Sugiyama LIN7C MALS3 VELI3 EEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLKRGDQL
Q9NWU1 S108 Sugiyama OXSM VAAYVPRGSDEGQFNEQNFVsKSDIKSMSSPTIMAIGAAEL
Q9NYB9 S22 Sugiyama ABI2 ARGBPIA AELQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSAD
Q9NZB2 S417 Sugiyama FAM120A C9orf10 KIAA0183 OSSA LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERssPI
Q9P265 S203 Sugiyama DIP2B KIAA1463 stsssASSTLSHGEVKGtsGsLADVFANtRIENFSAPPDVT
Q9P2E9 S896 Sugiyama RRBP1 KIAA1398 SEEALQKRLDEVSRELCHTQsSHASLRADAEKAQEQQQQMA
Q9UBF8 T426 Sugiyama PI4KB PIK4CB CENFDTTSVPARIPENRIRstRsVENLPECGItHEQRAGSF
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UGU0 S1187 Sugiyama TCF20 KIAA0292 SPBP sDGLPNKGMELKHGSQKLQEsCWDLsRQTsPAKSSGPPGMS
Q9UGV2 S331 Sugiyama NDRG3 QGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQ
Q9UI15 S185 Sugiyama TAGLN3 NP25 EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______
Q9UJU6 T270 Sugiyama DBNL CMAP SH3P7 PP5423 EQESAVHPREIFKQKERAMsttsIssPQPGKLRsPFLQKQL
Q9UKV8 S387 Sugiyama AGO2 EIF2C2 ATARSAPDRQEEISKLMRsAsFNTDPyVREFGIMVKDEMTD
Q9UNH7 S316 Sugiyama SNX6 LKYYLRESQAAKDLLYRRsRsLVDYENANKALDKARAKNKD
Q9UPQ0 S1054 Sugiyama LIMCH1 KIAA1102 YFHIQCFRCGICKGQLGDAVsGTDVRIRNGLLNCNDCyMRS
Q9UPQ0 S201 Sugiyama LIMCH1 KIAA1102 DCWDsERsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVV
Q9UQ35 S1541 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ssVDQKtVARtPLGQRsRsGssQELDVKPsAsPQERsEsDs
Q9UQ35 S2692 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS
Q9UQL6 S259 PSP HDAC5 KIAA0600 KLPLPGPYDSRDDFPLRKTAsEPNLKVRSRLKQKVAERRss
Q9Y2B0 S116 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA
Q9Y2B0 S178 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NVKDKLCSKRtDLCDHALHIsHDEL________________
Q9Y2B0 S55 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDELEWEIAQVDPKKTIQMGsFRINPDGsQsVVEVPyARsE
Q9Y2B0 S63 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2B0 T79 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGEQIDPs
Q9Y2I7 S307 Sugiyama PIKFYVE KIAA0981 PIP5K3 TRLVSVQEDAGKsPARNRsAsItNLsLDRsGsPMVPSYEts
Q9Y2L1 S633 Sugiyama DIS3 KIAA1008 RRP44 LNKLAKILKKRRIEKGALTLssPEVRFHMDSETHDPIDLQT
Q9Y2U5 S239 Sugiyama MAP3K2 MAPKKK2 MEKK2 SLDSPLDGESYPKSRMPRAQsyPDNHQEFSDyDNPIFEKFG
Q9Y316 S91 Sugiyama MEMO1 C2orf4 MEMO NS5ATP7 CGI-27 TRRIFILGPSHHVPLsRCALsSVDIYRTPLYDLRIDQKIYG
Q9Y394 S328 Sugiyama DHRS7 DHRS7A RETSDR4 SDR34C1 CGI-86 UNQ285/PRO3448 ITNKMGKKRIENFKSGVDADssyFKIFKTKHD_________
Q9Y3B8 S203 Sugiyama REXO2 SFN SMFN CGI-114 EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK
Q9Y3F4 T109 Sugiyama STRAP MAWD UNRIP VSGDELMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDL
Q9Y3F4 Y114 Sugiyama STRAP MAWD UNRIP LMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDLNKPEA
Q9Y3S2 S27 Sugiyama ZNF330 NOA36 GARKKAENRREREKQLRAsRstIDLAKHPCNASMECDKCQR
Q9Y3S2 S310 Sugiyama ZNF330 NOA36 DsDtEssDLFTNLNLGRTYAsGYAHyEEQEN__________
Q9Y450 S69 Sugiyama HBS1L HBS1 KIAA1038 sVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCLDHMR
Q9Y490 S1535 Sugiyama TLN1 KIAA1027 TLN RTTNPTAKRQFVQSAKEVANsTANLVKTIKALDGAFTEENR
Q9Y4G6 S1537 Sugiyama TLN2 KIAA0320 KTANPVAKRHFVQSAKEVANsTANLVKTIKALDGDFSEDNR
Q9Y4L1 S742 Sugiyama HYOU1 GRP170 HSPH4 ORP150 KLQDLTLRDLEKQEREKAANsLEAFIFEtQDKLyQPEyQEV
Q9Y4L1 T750 Sugiyama HYOU1 GRP170 HSPH4 ORP150 DLEKQEREKAANsLEAFIFEtQDKLyQPEyQEVsTEEQREE
Q9Y4W2 S636 Sugiyama LAS1L MSTP060 EsPtAENARLLAQKRGALQGsAWQVssEDVRWDTFPLGRMP
Q9Y4X5 S517 Sugiyama ARIH1 ARI MOP6 UBCH7BP HUSSY-27 DLENATEVLSGYLERDIsQDsLQDIKQKVQDKYRYCESRRR
Q9Y5S2 S221 Sugiyama CDC42BPB KIAA1124 IKPDNVLLDVNGHIRLADFGsCLKMNDDGTVQSSVAVGTPD
Q9Y5S2 S474 Sugiyama CDC42BPB KIAA1124 KLELSRKLQESTQTVQsLHGsSRALSNsNRDKEIKKLNEEI
Q9Y696 S226 Sugiyama CLIC4 RNFDIPKEMTGIWRYLtNAysRDEFtNtCPsDKEVEIAysD
Q9Y6E0 S400 Sugiyama STK24 MST3 STK3 ISPLFAELKEKsQACGGNLGsIEELRGAIYLAEEACPGISD
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Signal Transduction R-HSA-162582 6.046386e-12 11.219 0 0
Axon guidance R-HSA-422475 5.496927e-09 8.260 0 0
Cell Cycle R-HSA-1640170 1.088710e-08 7.963 0 0
Mitotic Prometaphase R-HSA-68877 6.810057e-08 7.167 0 0
Nervous system development R-HSA-9675108 6.925823e-08 7.160 0 0
Cell Cycle, Mitotic R-HSA-69278 2.079072e-07 6.682 0 0
NRAGE signals death through JNK R-HSA-193648 9.332579e-07 6.030 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 9.305406e-07 6.031 0 0
Kinesins R-HSA-983189 2.821147e-06 5.550 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.292869e-06 5.482 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.256399e-06 5.487 0 0
Intracellular signaling by second messengers R-HSA-9006925 3.741052e-06 5.427 0 0
Cell Cycle Checkpoints R-HSA-69620 4.619060e-06 5.335 0 0
Post NMDA receptor activation events R-HSA-438064 4.962863e-06 5.304 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.005385e-05 4.998 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.109344e-05 4.955 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.517202e-05 4.819 0 0
M Phase R-HSA-68886 2.242088e-05 4.649 0 0
Separation of Sister Chromatids R-HSA-2467813 2.347566e-05 4.629 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.473753e-05 4.607 0 0
G2/M Transition R-HSA-69275 3.213391e-05 4.493 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.629750e-05 4.440 0 0
Apoptotic execution phase R-HSA-75153 4.549076e-05 4.342 0 0
Amplification of signal from the kinetochores R-HSA-141424 4.949025e-05 4.305 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 4.949025e-05 4.305 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 5.684212e-05 4.245 0 0
G alpha (12/13) signalling events R-HSA-416482 6.218059e-05 4.206 0 0
Nuclear Receptor transcription pathway R-HSA-383280 6.218059e-05 4.206 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 5.684212e-05 4.245 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 6.184932e-05 4.209 0 0
Mitotic Anaphase R-HSA-68882 5.535726e-05 4.257 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 6.811867e-05 4.167 0 0
AURKA Activation by TPX2 R-HSA-8854518 8.536411e-05 4.069 0 0
Centrosome maturation R-HSA-380287 8.433751e-05 4.074 0 0
Death Receptor Signaling R-HSA-73887 9.343148e-05 4.030 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.026397e-04 3.989 0 0
Regulation of TP53 Activity R-HSA-5633007 1.035836e-04 3.985 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.158913e-04 3.936 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.158913e-04 3.936 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.123684e-04 3.949 0 0
Neurodegenerative Diseases R-HSA-8863678 1.317923e-04 3.880 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.317923e-04 3.880 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.511738e-04 3.821 0 0
L1CAM interactions R-HSA-373760 1.565902e-04 3.805 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.860595e-04 3.730 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.987967e-04 3.702 0 0
Apoptosis R-HSA-109581 2.481866e-04 3.605 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 3.146177e-04 3.502 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 3.750092e-04 3.426 0 0
Ion homeostasis R-HSA-5578775 4.368195e-04 3.360 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 4.320686e-04 3.364 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 5.444617e-04 3.264 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 7.384309e-04 3.132 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 8.103219e-04 3.091 0 0
TRP channels R-HSA-3295583 8.075658e-04 3.093 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 8.100272e-04 3.092 0 0
Interleukin-37 signaling R-HSA-9008059 7.865567e-04 3.104 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 8.336938e-04 3.079 0 0
Programmed Cell Death R-HSA-5357801 8.960883e-04 3.048 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 9.684640e-04 3.014 0 0
Muscle contraction R-HSA-397014 1.019047e-03 2.992 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 1.106059e-03 2.956 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.105159e-03 2.957 0 0
Recycling pathway of L1 R-HSA-437239 1.107393e-03 2.956 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.116642e-03 2.952 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.199051e-03 2.921 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.267952e-03 2.897 0 0
Aggrephagy R-HSA-9646399 1.372762e-03 2.862 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.513217e-03 2.820 0 0
Membrane Trafficking R-HSA-199991 1.559211e-03 2.807 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 1.787175e-03 2.748 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 1.787175e-03 2.748 0 0
DAG and IP3 signaling R-HSA-1489509 1.839912e-03 2.735 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 1.965951e-03 2.706 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.925970e-03 2.715 0 0
Signaling by ROBO receptors R-HSA-376176 1.886321e-03 2.724 0 0
Signaling by RAF1 mutants R-HSA-9656223 2.070457e-03 2.684 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.223874e-03 2.653 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.223874e-03 2.653 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.223874e-03 2.653 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.142327e-03 2.669 0 0
Signaling by RAS mutants R-HSA-6802949 2.223874e-03 2.653 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.518788e-03 2.599 0 0
Rap1 signalling R-HSA-392517 2.585601e-03 2.587 0 0
Cardiac conduction R-HSA-5576891 2.473523e-03 2.607 0 0
FOXO-mediated transcription R-HSA-9614085 2.599487e-03 2.585 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.812757e-03 2.551 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 3.280881e-03 2.484 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.333772e-03 2.477 0 0
Semaphorin interactions R-HSA-373755 3.396446e-03 2.469 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 3.891281e-03 2.410 0 0
G2/M DNA damage checkpoint R-HSA-69473 3.884962e-03 2.411 0 0
RET signaling R-HSA-8853659 3.894169e-03 2.410 0 0
Calmodulin induced events R-HSA-111933 3.894169e-03 2.410 0 0
CaM pathway R-HSA-111997 3.894169e-03 2.410 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 3.842322e-03 2.415 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 4.224828e-03 2.374 0 0
PKMTs methylate histone lysines R-HSA-3214841 4.166929e-03 2.380 0 0
Cilium Assembly R-HSA-5617833 4.340879e-03 2.362 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.369235e-03 2.360 0 0
Signaling by Hippo R-HSA-2028269 4.650612e-03 2.332 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 5.184837e-03 2.285 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 5.061517e-03 2.296 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 5.184837e-03 2.285 0 0
Signaling by NTRKs R-HSA-166520 5.391596e-03 2.268 0 0
Cellular responses to stimuli R-HSA-8953897 5.429667e-03 2.265 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 5.469476e-03 2.262 0 0
MyD88-independent TLR4 cascade R-HSA-166166 5.586871e-03 2.253 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 5.586871e-03 2.253 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 5.855881e-03 2.232 0 0
Neuronal System R-HSA-112316 5.513713e-03 2.259 0 0
Cytokine Signaling in Immune system R-HSA-1280215 5.557251e-03 2.255 0 0
Ca-dependent events R-HSA-111996 5.965799e-03 2.224 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 6.035683e-03 2.219 0 0
RAF activation R-HSA-5673000 6.512282e-03 2.186 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 6.793749e-03 2.168 0 0
Diseases of programmed cell death R-HSA-9645723 6.957592e-03 2.158 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 6.856459e-03 2.164 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 6.856459e-03 2.164 0 0
PI Metabolism R-HSA-1483255 6.840239e-03 2.165 0 0
Signaling by ALK R-HSA-201556 6.856459e-03 2.164 0 0
mTORC1-mediated signalling R-HSA-166208 7.379324e-03 2.132 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 7.381813e-03 2.132 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 8.044962e-03 2.094 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 8.044962e-03 2.094 0 0
MAPK family signaling cascades R-HSA-5683057 8.188638e-03 2.087 0 0
MHC class II antigen presentation R-HSA-2132295 8.336425e-03 2.079 0 0
ISG15 antiviral mechanism R-HSA-1169408 8.764829e-03 2.057 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 8.895428e-03 2.051 0 0
Chromatin modifying enzymes R-HSA-3247509 9.124099e-03 2.040 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 9.271466e-03 2.033 0 0
Regulation of TP53 Degradation R-HSA-6804757 9.416575e-03 2.026 0 0
Cellular responses to stress R-HSA-2262752 9.466758e-03 2.024 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.003895e-02 1.998 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 1.091501e-02 1.962 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 1.091501e-02 1.962 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 1.091501e-02 1.962 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.020071e-02 1.991 0 0
Integrin signaling R-HSA-354192 1.082690e-02 1.965 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.082690e-02 1.965 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.082690e-02 1.965 0 0
PLC beta mediated events R-HSA-112043 1.090245e-02 1.962 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.027030e-02 1.988 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.098915e-02 1.959 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 1.117503e-02 1.952 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.120539e-02 1.951 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.130015e-02 1.947 0 0
Cellular response to heat stress R-HSA-3371556 1.169785e-02 1.932 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 1.286186e-02 1.891 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 1.240523e-02 1.906 0 0
Platelet calcium homeostasis R-HSA-418360 1.240523e-02 1.906 0 0
Selective autophagy R-HSA-9663891 1.279939e-02 1.893 0 0
Interleukin-1 family signaling R-HSA-446652 1.239580e-02 1.907 0 0
Signaling by Interleukins R-HSA-449147 1.273218e-02 1.895 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.414312e-02 1.849 0 0
HDMs demethylate histones R-HSA-3214842 1.414312e-02 1.849 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 1.414504e-02 1.849 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.458141e-02 1.836 0 0
Regulation of PTEN localization R-HSA-8948747 1.458141e-02 1.836 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 1.555202e-02 1.808 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.600678e-02 1.796 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.600678e-02 1.796 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.545883e-02 1.811 0 0
RNA Polymerase II Transcription R-HSA-73857 1.632554e-02 1.787 0 0
NGF-stimulated transcription R-HSA-9031628 1.531661e-02 1.815 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.600678e-02 1.796 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.600678e-02 1.796 0 0
Translation initiation complex formation R-HSA-72649 1.714900e-02 1.766 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 1.719728e-02 1.765 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.965804e-02 1.706 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.965804e-02 1.706 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.965804e-02 1.706 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.965804e-02 1.706 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 1.813580e-02 1.741 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 1.813580e-02 1.741 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.955176e-02 1.709 0 0
Polo-like kinase mediated events R-HSA-156711 1.791381e-02 1.747 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 1.816825e-02 1.741 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.813580e-02 1.741 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.791381e-02 1.747 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.967461e-02 1.706 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.968758e-02 1.706 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 2.033980e-02 1.692 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.058124e-02 1.687 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.062520e-02 1.686 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.062520e-02 1.686 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 2.070952e-02 1.684 0 0
Signaling by GSK3beta mutants R-HSA-5339716 2.096335e-02 1.679 0 0
Sodium/Calcium exchangers R-HSA-425561 2.096335e-02 1.679 0 0
Regulation by c-FLIP R-HSA-3371378 2.098350e-02 1.678 0 0
Dimerization of procaspase-8 R-HSA-69416 2.098350e-02 1.678 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 2.098350e-02 1.678 0 0
Diseases of mitotic cell cycle R-HSA-9675126 2.120206e-02 1.674 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 2.215285e-02 1.655 0 0
EPH-Ephrin signaling R-HSA-2682334 2.137317e-02 1.670 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.392950e-02 1.621 0 0
G-protein mediated events R-HSA-112040 2.281549e-02 1.642 0 0
Chromatin organization R-HSA-4839726 2.333237e-02 1.632 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.215285e-02 1.655 0 0
Heme signaling R-HSA-9707616 2.393065e-02 1.621 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.428929e-02 1.615 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.428929e-02 1.615 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.428929e-02 1.615 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.776499e-02 1.557 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.776499e-02 1.557 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 2.752375e-02 1.560 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 2.752375e-02 1.560 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 2.752375e-02 1.560 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 2.752375e-02 1.560 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 2.752375e-02 1.560 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 2.507318e-02 1.601 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 2.751498e-02 1.560 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 2.751498e-02 1.560 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.480706e-02 1.605 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 2.480706e-02 1.605 0 0
Prolonged ERK activation events R-HSA-169893 2.507318e-02 1.601 0 0
MTOR signalling R-HSA-165159 2.800276e-02 1.553 0 0
Signaling by LTK R-HSA-9842663 2.752375e-02 1.560 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 2.507318e-02 1.601 0 0
Toll-like Receptor Cascades R-HSA-168898 2.615314e-02 1.582 0 0
Autophagy R-HSA-9612973 2.611696e-02 1.583 0 0
Generic Transcription Pathway R-HSA-212436 2.594398e-02 1.586 0 0
Signaling by PTK6 R-HSA-8848021 2.684723e-02 1.571 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 2.684723e-02 1.571 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.495986e-02 1.603 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 2.752375e-02 1.560 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 2.786924e-02 1.555 0 0
Nephrin family interactions R-HSA-373753 2.751498e-02 1.560 0 0
PKR-mediated signaling R-HSA-9833482 2.815302e-02 1.550 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 2.818958e-02 1.550 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 2.872346e-02 1.542 0 0
CASP8 activity is inhibited R-HSA-5218900 2.898361e-02 1.538 0 0
ALK mutants bind TKIs R-HSA-9700645 2.898361e-02 1.538 0 0
Signaling by VEGF R-HSA-194138 2.905710e-02 1.537 0 0
Hedgehog 'off' state R-HSA-5610787 2.906441e-02 1.537 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 2.923691e-02 1.534 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 3.080760e-02 1.511 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 3.297143e-02 1.482 0 0
Diseases of Telomere Maintenance R-HSA-9673013 3.297143e-02 1.482 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 3.297143e-02 1.482 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 3.297143e-02 1.482 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 3.297143e-02 1.482 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 3.297143e-02 1.482 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 3.297143e-02 1.482 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 3.467000e-02 1.460 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 3.531346e-02 1.452 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 3.138868e-02 1.503 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 3.436923e-02 1.464 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 3.389581e-02 1.470 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 3.389581e-02 1.470 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.536961e-02 1.451 0 0
Formation of a pool of free 40S subunits R-HSA-72689 3.100057e-02 1.509 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.156469e-02 1.501 0 0
Signaling by ERBB2 R-HSA-1227986 3.536961e-02 1.451 0 0
G2/M Checkpoints R-HSA-69481 3.384763e-02 1.470 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.211128e-02 1.493 0 0
Frs2-mediated activation R-HSA-170968 3.531346e-02 1.452 0 0
Eukaryotic Translation Elongation R-HSA-156842 3.614787e-02 1.442 0 0
Long-term potentiation R-HSA-9620244 3.430904e-02 1.465 0 0
Potassium Channels R-HSA-1296071 3.385255e-02 1.470 0 0
Gene expression (Transcription) R-HSA-74160 3.305919e-02 1.481 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 3.531346e-02 1.452 0 0
Rab regulation of trafficking R-HSA-9007101 3.592821e-02 1.445 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.508424e-02 1.455 0 0
Signaling by ALK in cancer R-HSA-9700206 3.508424e-02 1.455 0 0
RAB geranylgeranylation R-HSA-8873719 3.536961e-02 1.451 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 3.731617e-02 1.428 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 3.868265e-02 1.412 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 3.868968e-02 1.412 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 3.911901e-02 1.408 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 4.121523e-02 1.385 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.212588e-02 1.375 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 4.256063e-02 1.371 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.312830e-02 1.365 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 4.379592e-02 1.359 0 0
HSF1-dependent transactivation R-HSA-3371571 4.409314e-02 1.356 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 4.479864e-02 1.349 0 0
Deubiquitination R-HSA-5688426 4.495266e-02 1.347 0 0
Macroautophagy R-HSA-1632852 4.512684e-02 1.346 0 0
Nuclear Envelope Breakdown R-HSA-2980766 4.649538e-02 1.333 0 0
Chaperone Mediated Autophagy R-HSA-9613829 4.702110e-02 1.328 0 0
Ephrin signaling R-HSA-3928664 4.702110e-02 1.328 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 4.820794e-02 1.317 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 4.820794e-02 1.317 0 0
MAP2K and MAPK activation R-HSA-5674135 4.888061e-02 1.311 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 5.014405e-02 1.300 0 0
Signaling by APC mutants R-HSA-4839744 5.014405e-02 1.300 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 5.014405e-02 1.300 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 5.014405e-02 1.300 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 5.014405e-02 1.300 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 5.414266e-02 1.266 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 5.414266e-02 1.266 0 0
TRIF-mediated programmed cell death R-HSA-2562578 5.469533e-02 1.262 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.480943e-02 1.261 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 5.331502e-02 1.273 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 5.331502e-02 1.273 0 0
Voltage gated Potassium channels R-HSA-1296072 5.118952e-02 1.291 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 6.091499e-02 1.215 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 5.428937e-02 1.265 0 0
mRNA Splicing R-HSA-72172 5.903253e-02 1.229 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 5.715573e-02 1.243 0 0
IGF1R signaling cascade R-HSA-2428924 5.356080e-02 1.271 0 0
p75NTR signals via NF-kB R-HSA-193639 5.480943e-02 1.261 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.567070e-02 1.254 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 5.897036e-02 1.229 0 0
Regulation of necroptotic cell death R-HSA-5675482 5.331502e-02 1.273 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 5.971804e-02 1.224 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 5.331502e-02 1.273 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 5.977041e-02 1.224 0 0
MECP2 regulates transcription factors R-HSA-9022707 5.469533e-02 1.262 0 0
IRE1alpha activates chaperones R-HSA-381070 5.428937e-02 1.265 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 5.897036e-02 1.229 0 0
XBP1(S) activates chaperone genes R-HSA-381038 5.357988e-02 1.271 0 0
Peptide chain elongation R-HSA-156902 6.315070e-02 1.200 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 6.339378e-02 1.198 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 6.339378e-02 1.198 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 6.339378e-02 1.198 0 0
Activation of RAC1 R-HSA-428540 6.339378e-02 1.198 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 6.339378e-02 1.198 0 0
Signaling by AMER1 mutants R-HSA-4839748 6.339378e-02 1.198 0 0
Signaling by AXIN mutants R-HSA-4839735 6.339378e-02 1.198 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 6.395231e-02 1.194 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 6.395231e-02 1.194 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 6.411770e-02 1.193 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 6.416547e-02 1.193 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 6.564285e-02 1.183 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 6.605848e-02 1.180 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 6.658092e-02 1.177 0 0
Breakdown of the nuclear lamina R-HSA-352238 6.772960e-02 1.169 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 6.772960e-02 1.169 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 6.772960e-02 1.169 0 0
MyD88 deficiency (TLR5) R-HSA-5602680 6.772960e-02 1.169 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 6.772960e-02 1.169 0 0
Adrenoceptors R-HSA-390696 7.200338e-02 1.143 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 7.200338e-02 1.143 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 7.271270e-02 1.138 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 7.271270e-02 1.138 0 0
Activation of BH3-only proteins R-HSA-114452 7.271270e-02 1.138 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 7.271270e-02 1.138 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 7.776566e-02 1.109 0 0
ARMS-mediated activation R-HSA-170984 9.175525e-02 1.037 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 9.175525e-02 1.037 0 0
p75NTR recruits signalling complexes R-HSA-209543 7.842198e-02 1.106 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 7.842198e-02 1.106 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 7.842198e-02 1.106 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 7.971175e-02 1.098 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 7.847095e-02 1.105 0 0
G1/S-Specific Transcription R-HSA-69205 8.776199e-02 1.057 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 8.542569e-02 1.068 0 0
mRNA 3'-end processing R-HSA-72187 8.779100e-02 1.057 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 7.961919e-02 1.099 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.887978e-02 1.103 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.887978e-02 1.103 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 8.268998e-02 1.083 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 7.740376e-02 1.111 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 7.609405e-02 1.119 0 0
Homology Directed Repair R-HSA-5693538 8.908091e-02 1.050 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 8.986542e-02 1.046 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 9.175525e-02 1.037 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 8.171768e-02 1.088 0 0
Signalling to ERKs R-HSA-187687 7.813112e-02 1.107 0 0
Interferon Signaling R-HSA-913531 8.071526e-02 1.093 0 0
Trafficking of AMPA receptors R-HSA-399719 8.268998e-02 1.083 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.787785e-02 1.109 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.787785e-02 1.109 0 0
Neurexins and neuroligins R-HSA-6794361 8.779100e-02 1.057 0 0
Platelet activation, signaling and aggregation R-HSA-76002 8.069801e-02 1.093 0 0
Calcineurin activates NFAT R-HSA-2025928 9.175525e-02 1.037 0 0
Signaling by Hedgehog R-HSA-5358351 8.054559e-02 1.094 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 8.425317e-02 1.074 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 7.776566e-02 1.109 0 0
NrCAM interactions R-HSA-447038 7.776566e-02 1.109 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 9.175525e-02 1.037 0 0
FLT3 Signaling R-HSA-9607240 8.227548e-02 1.085 0 0
Glycolysis R-HSA-70171 7.406289e-02 1.130 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 7.435600e-02 1.129 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 9.175525e-02 1.037 0 0
Unfolded Protein Response (UPR) R-HSA-381119 8.539195e-02 1.069 0 0
Chaperonin-mediated protein folding R-HSA-390466 9.226548e-02 1.035 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 9.345010e-02 1.029 0 0
Specification of primordial germ cells R-HSA-9827857 9.418554e-02 1.026 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.435050e-02 1.025 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 9.518564e-02 1.021 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 9.518564e-02 1.021 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 9.922773e-02 1.003 0 0
Interaction between L1 and Ankyrins R-HSA-445095 9.922773e-02 1.003 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 9.922773e-02 1.003 0 0
G1/S Transition R-HSA-69206 9.946150e-02 1.002 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.015527e-01 0.993 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.314323e-01 0.881 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 1.314323e-01 0.881 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 1.314323e-01 0.881 0 0
Regulation of TP53 Expression R-HSA-6804754 1.100566e-01 0.958 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.100566e-01 0.958 0 0
Potassium transport channels R-HSA-1296067 1.100566e-01 0.958 0 0
TRAIL signaling R-HSA-75158 1.050860e-01 0.978 0 0
GLI proteins bind promoters of Hh responsive genes to promote transcription R-HSA-5635851 1.050860e-01 0.978 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 1.355702e-01 0.868 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 1.355702e-01 0.868 0 0
CREB phosphorylation R-HSA-199920 1.355702e-01 0.868 0 0
Formation of apoptosome R-HSA-111458 1.137892e-01 0.944 0 0
Regulation of the apoptosome activity R-HSA-9627069 1.137892e-01 0.944 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.137892e-01 0.944 0 0
DCC mediated attractive signaling R-HSA-418885 1.336033e-01 0.874 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.336033e-01 0.874 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.099679e-01 0.959 0 0
PKA activation R-HSA-163615 1.099679e-01 0.959 0 0
PKA activation in glucagon signalling R-HSA-164378 1.099679e-01 0.959 0 0
Notch-HLH transcription pathway R-HSA-350054 1.048768e-01 0.979 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 1.270077e-01 0.896 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.207398e-01 0.918 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.330663e-01 0.876 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 1.353647e-01 0.868 0 0
PTEN Regulation R-HSA-6807070 1.205627e-01 0.919 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.230033e-01 0.910 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.191655e-01 0.924 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.326608e-01 0.877 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.129452e-01 0.947 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.172950e-01 0.931 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.049886e-01 0.979 0 0
DNA Double Strand Break Response R-HSA-5693606 1.158945e-01 0.936 0 0
Interleukin-1 signaling R-HSA-9020702 1.191655e-01 0.924 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.090725e-01 0.962 0 0
Netrin-1 signaling R-HSA-373752 1.230033e-01 0.910 0 0
PI3K Cascade R-HSA-109704 1.243865e-01 0.905 0 0
Apoptotic factor-mediated response R-HSA-111471 1.099679e-01 0.959 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.050860e-01 0.978 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.073151e-01 0.969 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.283666e-01 0.892 0 0
S Phase R-HSA-69242 1.050910e-01 0.978 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.099679e-01 0.959 0 0
MAP kinase activation R-HSA-450294 1.156835e-01 0.937 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 1.050860e-01 0.978 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 1.050860e-01 0.978 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 1.136122e-01 0.945 0 0
Protein-protein interactions at synapses R-HSA-6794362 1.147149e-01 0.940 0 0
Host Interactions of HIV factors R-HSA-162909 1.266121e-01 0.898 0 0
Regulated Necrosis R-HSA-5218859 1.251029e-01 0.903 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.353647e-01 0.868 0 0
Transmission across Chemical Synapses R-HSA-112315 1.190333e-01 0.924 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 1.050860e-01 0.978 0 0
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization R-HSA-180897 1.100566e-01 0.958 0 0
The NLRP3 inflammasome R-HSA-844456 1.270077e-01 0.896 0 0
Co-stimulation by CD28 R-HSA-389356 1.038211e-01 0.984 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.336033e-01 0.874 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.067206e-01 0.972 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.177457e-01 0.929 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.354680e-01 0.868 0 0
TBC/RABGAPs R-HSA-8854214 1.119194e-01 0.951 0 0
Glucose metabolism R-HSA-70326 1.215622e-01 0.915 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.049886e-01 0.979 0 0
Signaling by Leptin R-HSA-2586552 1.137892e-01 0.944 0 0
Gap junction assembly R-HSA-190861 1.303533e-01 0.885 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.365224e-01 0.865 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.379004e-01 0.860 0 0
Protein folding R-HSA-391251 1.383858e-01 0.859 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.408313e-01 0.851 0 0
Signaling by NOTCH1 R-HSA-1980143 1.433871e-01 0.843 0 0
Interleukin-12 signaling R-HSA-9020591 1.433871e-01 0.843 0 0
Influenza Infection R-HSA-168255 1.435662e-01 0.843 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.447441e-01 0.839 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 1.452394e-01 0.838 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 1.452394e-01 0.838 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 1.452394e-01 0.838 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 1.452394e-01 0.838 0 0
Signal transduction by L1 R-HSA-445144 1.452394e-01 0.838 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.458633e-01 0.836 0 0
Ion transport by P-type ATPases R-HSA-936837 1.458633e-01 0.836 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.460351e-01 0.836 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.460351e-01 0.836 0 0
Diseases of DNA repair R-HSA-9675135 1.469194e-01 0.833 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.470681e-01 0.832 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 1.470681e-01 0.832 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 1.522345e-01 0.817 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 1.522345e-01 0.817 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.550397e-01 0.810 0 0
Phosphorylation of the APC/C R-HSA-176412 1.550397e-01 0.810 0 0
Phase 4 - resting membrane potential R-HSA-5576886 1.550397e-01 0.810 0 0
Activation of SMO R-HSA-5635838 1.550397e-01 0.810 0 0
Downstream signal transduction R-HSA-186763 1.563687e-01 0.806 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 1.573642e-01 0.803 0 0
FasL/ CD95L signaling R-HSA-75157 1.573642e-01 0.803 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 1.591737e-01 0.798 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 1.596252e-01 0.797 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.596252e-01 0.797 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.076132e-01 0.683 0 0
Signaling by MAP2K mutants R-HSA-9652169 2.076132e-01 0.683 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.686500e-01 0.773 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.686500e-01 0.773 0 0
PTK6 Expression R-HSA-8849473 1.686500e-01 0.773 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 1.686500e-01 0.773 0 0
Type I hemidesmosome assembly R-HSA-446107 2.037553e-01 0.691 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 2.037553e-01 0.691 0 0
FGFR1b ligand binding and activation R-HSA-190370 2.037553e-01 0.691 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.638531e-01 0.786 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.913910e-01 0.718 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.913910e-01 0.718 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 2.403369e-01 0.619 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 2.403369e-01 0.619 0 0
Lipophagy R-HSA-9613354 2.403369e-01 0.619 0 0
WNT mediated activation of DVL R-HSA-201688 2.403369e-01 0.619 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 1.777849e-01 0.750 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 2.202478e-01 0.657 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.645841e-01 0.784 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.016898e-01 0.695 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.016898e-01 0.695 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 2.016898e-01 0.695 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 1.726776e-01 0.763 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 2.074176e-01 0.683 0 0
Striated Muscle Contraction R-HSA-390522 2.074176e-01 0.683 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 2.074176e-01 0.683 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 2.277301e-01 0.643 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 2.277301e-01 0.643 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.277301e-01 0.643 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.824588e-01 0.739 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 1.743417e-01 0.759 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 2.266432e-01 0.645 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.656479e-01 0.781 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.779962e-01 0.750 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 2.219319e-01 0.654 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 2.211788e-01 0.655 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.939281e-01 0.712 0 0
ESR-mediated signaling R-HSA-8939211 1.861479e-01 0.730 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.265969e-01 0.645 0 0
Circadian clock R-HSA-9909396 2.073507e-01 0.683 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 1.824588e-01 0.739 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 1.686500e-01 0.773 0 0
G0 and Early G1 R-HSA-1538133 1.726776e-01 0.763 0 0
IRS-mediated signalling R-HSA-112399 2.122958e-01 0.673 0 0
DNA Damage Bypass R-HSA-73893 1.869147e-01 0.728 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.828130e-01 0.738 0 0
Insulin receptor signalling cascade R-HSA-74751 2.219951e-01 0.654 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.775420e-01 0.751 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.894823e-01 0.722 0 0
Cellular response to starvation R-HSA-9711097 1.701279e-01 0.769 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 1.737978e-01 0.760 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 2.257410e-01 0.646 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.887064e-01 0.724 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.076132e-01 0.683 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 1.686500e-01 0.773 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 2.403369e-01 0.619 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.065418e-01 0.685 0 0
Opioid Signalling R-HSA-111885 2.015610e-01 0.696 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 2.084310e-01 0.681 0 0
Effects of PIP2 hydrolysis R-HSA-114508 2.074176e-01 0.683 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.884319e-01 0.725 0 0
TNF signaling R-HSA-75893 1.983515e-01 0.703 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.076132e-01 0.683 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 2.037553e-01 0.691 0 0
Synaptic adhesion-like molecules R-HSA-8849932 2.265969e-01 0.645 0 0
DARPP-32 events R-HSA-180024 2.277301e-01 0.643 0 0
HIV Infection R-HSA-162906 2.082562e-01 0.681 0 0
TCF dependent signaling in response to WNT R-HSA-201681 2.192395e-01 0.659 0 0
Regulation of TNFR1 signaling R-HSA-5357905 2.359135e-01 0.627 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.869147e-01 0.728 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 1.884319e-01 0.725 0 0
Nuclear import of Rev protein R-HSA-180746 2.257410e-01 0.646 0 0
Cellular Senescence R-HSA-2559583 1.957616e-01 0.708 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 1.895979e-01 0.722 0 0
Signaling by WNT in cancer R-HSA-4791275 1.726776e-01 0.763 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 2.229433e-01 0.652 0 0
GP1b-IX-V activation signalling R-HSA-430116 2.403369e-01 0.619 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 1.777849e-01 0.750 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.257410e-01 0.646 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 2.257410e-01 0.646 0 0
Interleukin-17 signaling R-HSA-448424 2.173898e-01 0.663 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 2.277301e-01 0.643 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.196532e-01 0.658 0 0
Signaling by TGFBR3 R-HSA-9839373 2.359135e-01 0.627 0 0
Eukaryotic Translation Termination R-HSA-72764 1.753303e-01 0.756 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 1.967142e-01 0.706 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.897112e-01 0.722 0 0
Vesicle-mediated transport R-HSA-5653656 2.032252e-01 0.692 0 0
mRNA Editing R-HSA-75072 2.403369e-01 0.619 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.777849e-01 0.750 0 0
Co-stimulation by ICOS R-HSA-9927354 2.037553e-01 0.691 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 2.403369e-01 0.619 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.265969e-01 0.645 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 2.265969e-01 0.645 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 2.077302e-01 0.683 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 1.738119e-01 0.760 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 2.059941e-01 0.686 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.257410e-01 0.646 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 2.229433e-01 0.652 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.976006e-01 0.704 0 0
Signaling by TGFB family members R-HSA-9006936 1.853513e-01 0.732 0 0
Signaling by SCF-KIT R-HSA-1433557 1.885669e-01 0.725 0 0
Gap junction trafficking and regulation R-HSA-157858 1.869147e-01 0.728 0 0
Platelet homeostasis R-HSA-418346 2.333411e-01 0.632 0 0
Interleukin-6 signaling R-HSA-1059683 2.202478e-01 0.657 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.884319e-01 0.725 0 0
Selenocysteine synthesis R-HSA-2408557 1.720366e-01 0.764 0 0
Interleukin-1 processing R-HSA-448706 2.403369e-01 0.619 0 0
Syndecan interactions R-HSA-3000170 2.283607e-01 0.641 0 0
Gap junction trafficking R-HSA-190828 2.038587e-01 0.691 0 0
Platelet sensitization by LDL R-HSA-432142 2.265969e-01 0.645 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 1.699101e-01 0.770 0 0
OAS antiviral response R-HSA-8983711 1.913910e-01 0.718 0 0
Interleukin-12 family signaling R-HSA-447115 2.040134e-01 0.690 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.446218e-01 0.612 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 2.446218e-01 0.612 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 2.455968e-01 0.610 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 2.455968e-01 0.610 0 0
TICAM1 deficiency - HSE R-HSA-5602566 2.455968e-01 0.610 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 2.455968e-01 0.610 0 0
Inhibition of PKR R-HSA-169131 2.455968e-01 0.610 0 0
Ub-specific processing proteases R-HSA-5689880 2.469272e-01 0.607 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.469375e-01 0.607 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 2.483528e-01 0.605 0 0
Activation of the pre-replicative complex R-HSA-68962 2.483528e-01 0.605 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.483528e-01 0.605 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.483528e-01 0.605 0 0
PI and PC transport between ER and Golgi membranes R-HSA-1483196 3.447613e-01 0.462 0 0
ARL13B-mediated ciliary trafficking of INPP5E R-HSA-5624958 3.447613e-01 0.462 0 0
Mitochondrial transcription initiation R-HSA-163282 3.447613e-01 0.462 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 3.447613e-01 0.462 0 0
TRAF3 deficiency - HSE R-HSA-5602571 3.447613e-01 0.462 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 3.447613e-01 0.462 0 0
Defective GFPT1 causes CMSTA1 R-HSA-4085023 3.447613e-01 0.462 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 3.447613e-01 0.462 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 3.447613e-01 0.462 0 0
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420 3.447613e-01 0.462 0 0
Intestinal infectious diseases R-HSA-8942233 3.447613e-01 0.462 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 3.447613e-01 0.462 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 3.447613e-01 0.462 0 0
IRS activation R-HSA-74713 2.592142e-01 0.586 0 0
G2 Phase R-HSA-68911 2.592142e-01 0.586 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.592142e-01 0.586 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 2.592142e-01 0.586 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 3.109443e-01 0.507 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 3.109443e-01 0.507 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 3.109443e-01 0.507 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 3.109443e-01 0.507 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 3.109443e-01 0.507 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 4.308958e-01 0.366 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 4.308958e-01 0.366 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 4.308958e-01 0.366 0 0
Essential pentosuria R-HSA-5662853 4.308958e-01 0.366 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 4.308958e-01 0.366 0 0
HHAT G278V doesn't palmitoylate Hh-Np R-HSA-5658034 4.308958e-01 0.366 0 0
TWIK related potassium channel (TREK) R-HSA-1299503 4.308958e-01 0.366 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 2.778824e-01 0.556 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 2.778824e-01 0.556 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 2.778824e-01 0.556 0 0
Folding of actin by CCT/TriC R-HSA-390450 2.778824e-01 0.556 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 2.501545e-01 0.602 0 0
STAT5 Activation R-HSA-9645135 3.618786e-01 0.441 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 3.618786e-01 0.441 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 3.618786e-01 0.441 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.808464e-01 0.552 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.808464e-01 0.552 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 2.523434e-01 0.598 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.511862e-01 0.600 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 2.787654e-01 0.555 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 3.120687e-01 0.506 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 3.120687e-01 0.506 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 3.540489e-01 0.451 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 3.540489e-01 0.451 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.540489e-01 0.451 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 3.540489e-01 0.451 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 4.113328e-01 0.386 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 4.113328e-01 0.386 0 0
CHL1 interactions R-HSA-447041 4.113328e-01 0.386 0 0
Netrin mediated repulsion signals R-HSA-418886 4.113328e-01 0.386 0 0
SOS-mediated signalling R-HSA-112412 4.113328e-01 0.386 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 4.113328e-01 0.386 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 4.113328e-01 0.386 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 2.746102e-01 0.561 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 3.057001e-01 0.515 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 3.057001e-01 0.515 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 3.057001e-01 0.515 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 3.435803e-01 0.464 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.435803e-01 0.464 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 2.695164e-01 0.569 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 2.695164e-01 0.569 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 2.985196e-01 0.525 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 3.918912e-01 0.407 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 3.918912e-01 0.407 0 0
HSF1 activation R-HSA-3371511 2.639980e-01 0.578 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 3.228014e-01 0.491 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 3.228014e-01 0.491 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 3.751572e-01 0.426 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 3.751572e-01 0.426 0 0
RSK activation R-HSA-444257 4.588162e-01 0.338 0 0
Activation of RAS in B cells R-HSA-1169092 4.588162e-01 0.338 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 4.588162e-01 0.338 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 4.588162e-01 0.338 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 4.588162e-01 0.338 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.131313e-01 0.504 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.131313e-01 0.504 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 3.604786e-01 0.443 0 0
FGFR2 alternative splicing R-HSA-6803529 3.604786e-01 0.443 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.604786e-01 0.443 0 0
Telomere Extension By Telomerase R-HSA-171319 3.473447e-01 0.459 0 0
HIV elongation arrest and recovery R-HSA-167287 3.473447e-01 0.459 0 0
Pausing and recovery of HIV elongation R-HSA-167290 3.473447e-01 0.459 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 4.291415e-01 0.367 0 0
Formation of axial mesoderm R-HSA-9796292 4.291415e-01 0.367 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.244522e-01 0.489 0 0
Signaling by Erythropoietin R-HSA-9006335 3.720419e-01 0.429 0 0
Late endosomal microautophagy R-HSA-9615710 3.720419e-01 0.429 0 0
Dual Incision in GG-NER R-HSA-5696400 3.579026e-01 0.446 0 0
HIV Transcription Elongation R-HSA-167169 3.451597e-01 0.462 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.451597e-01 0.462 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.451597e-01 0.462 0 0
Viral mRNA Translation R-HSA-192823 2.623421e-01 0.581 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.299137e-01 0.482 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 3.805158e-01 0.420 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 3.805158e-01 0.420 0 0
Deadenylation of mRNA R-HSA-429947 4.154916e-01 0.381 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 4.377069e-01 0.359 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 4.377069e-01 0.359 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 4.655398e-01 0.332 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 4.655398e-01 0.332 0 0
snRNP Assembly R-HSA-191859 3.472114e-01 0.459 0 0
Metabolism of non-coding RNA R-HSA-194441 3.472114e-01 0.459 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 3.870177e-01 0.412 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 3.870177e-01 0.412 0 0
EGFR downregulation R-HSA-182971 4.214889e-01 0.375 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 4.427532e-01 0.354 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 4.683311e-01 0.329 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 4.683311e-01 0.329 0 0
Co-inhibition by CTLA4 R-HSA-389513 4.683311e-01 0.329 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.997183e-01 0.523 0 0
Signaling by EGFR in Cancer R-HSA-1643713 4.696948e-01 0.328 0 0
HATs acetylate histones R-HSA-3214847 3.843505e-01 0.415 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 4.983237e-01 0.302 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 4.983237e-01 0.302 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.962128e-01 0.304 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 4.165426e-01 0.380 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 4.165426e-01 0.380 0 0
Neutrophil degranulation R-HSA-6798695 3.424848e-01 0.465 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.901055e-01 0.310 0 0
Meiotic synapsis R-HSA-1221632 4.901055e-01 0.310 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 4.165426e-01 0.380 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 3.039788e-01 0.517 0 0
Signaling by EGFR R-HSA-177929 2.959092e-01 0.529 0 0
Specification of the neural plate border R-HSA-9834899 2.523434e-01 0.598 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 3.451597e-01 0.462 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 3.451597e-01 0.462 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.214889e-01 0.375 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 4.291415e-01 0.367 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.523434e-01 0.598 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.696948e-01 0.328 0 0
Ribosome-associated quality control R-HSA-9948299 3.492321e-01 0.457 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 3.660362e-01 0.436 0 0
Signaling by FGFR2 R-HSA-5654738 3.610881e-01 0.442 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 3.435803e-01 0.464 0 0
Termination of translesion DNA synthesis R-HSA-5656169 3.720419e-01 0.429 0 0
TGFBR3 expression R-HSA-9839394 2.746102e-01 0.561 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 3.918912e-01 0.407 0 0
Meiosis R-HSA-1500620 4.384429e-01 0.358 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 4.196109e-01 0.377 0 0
Signal attenuation R-HSA-74749 2.778824e-01 0.556 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 2.501545e-01 0.602 0 0
Myogenesis R-HSA-525793 2.985196e-01 0.525 0 0
Inwardly rectifying K+ channels R-HSA-1296065 4.460480e-01 0.351 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 4.253302e-01 0.371 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.696948e-01 0.328 0 0
Signaling by FGFR3 R-HSA-5654741 3.335210e-01 0.477 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 2.738940e-01 0.562 0 0
Josephin domain DUBs R-HSA-5689877 2.778824e-01 0.556 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.511862e-01 0.600 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 4.065944e-01 0.391 0 0
Signaling by FGFR4 R-HSA-5654743 2.953120e-01 0.530 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 3.100092e-01 0.509 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 3.109443e-01 0.507 0 0
Regulation of CDH11 function R-HSA-9762292 2.778824e-01 0.556 0 0
PI3K/AKT activation R-HSA-198203 2.778824e-01 0.556 0 0
CRMPs in Sema3A signaling R-HSA-399956 2.501545e-01 0.602 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 3.751572e-01 0.426 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 3.604786e-01 0.443 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.429805e-01 0.465 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 4.928210e-01 0.307 0 0
Signaling by FGFR1 R-HSA-5654736 4.149609e-01 0.382 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 4.398111e-01 0.357 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 4.377069e-01 0.359 0 0
Interleukin-9 signaling R-HSA-8985947 4.588162e-01 0.338 0 0
Late Phase of HIV Life Cycle R-HSA-162599 3.291141e-01 0.483 0 0
HIV Life Cycle R-HSA-162587 3.441426e-01 0.463 0 0
Triglyceride catabolism R-HSA-163560 4.031749e-01 0.395 0 0
Mitotic Prophase R-HSA-68875 4.285343e-01 0.368 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.592142e-01 0.586 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.618786e-01 0.441 0 0
NF-kB is activated and signals survival R-HSA-209560 3.540489e-01 0.451 0 0
VLDLR internalisation and degradation R-HSA-8866427 3.918912e-01 0.407 0 0
Regulation of IFNG signaling R-HSA-877312 3.918912e-01 0.407 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 3.918912e-01 0.407 0 0
cGMP effects R-HSA-418457 4.655398e-01 0.332 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 3.330663e-01 0.477 0 0
Ca2+ pathway R-HSA-4086398 4.700751e-01 0.328 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.985196e-01 0.525 0 0
Repression of WNT target genes R-HSA-4641265 3.918912e-01 0.407 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.870177e-01 0.412 0 0
Hedgehog 'on' state R-HSA-5632684 4.364691e-01 0.360 0 0
GPER1 signaling R-HSA-9634597 3.921735e-01 0.407 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 4.683311e-01 0.329 0 0
Glycogen metabolism R-HSA-8982491 3.451597e-01 0.462 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 3.412482e-01 0.467 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 4.118724e-01 0.385 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 4.118724e-01 0.385 0 0
Signaling by WNT R-HSA-195721 3.349513e-01 0.475 0 0
Transcription from mitochondrial promoters R-HSA-75944 4.308958e-01 0.366 0 0
mRNA Editing: C to U Conversion R-HSA-72200 4.113328e-01 0.386 0 0
Ca2+ activated K+ channels R-HSA-1296052 4.113328e-01 0.386 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 3.751572e-01 0.426 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 3.751572e-01 0.426 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 4.588162e-01 0.338 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 4.588162e-01 0.338 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 4.588162e-01 0.338 0 0
FGFR1c ligand binding and activation R-HSA-190373 4.291415e-01 0.367 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 2.795764e-01 0.553 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 4.983237e-01 0.302 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 4.944071e-01 0.306 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 3.435803e-01 0.464 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 3.473447e-01 0.459 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 3.720419e-01 0.429 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 3.451597e-01 0.462 0 0
Diseases of Immune System R-HSA-5260271 3.451597e-01 0.462 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 3.587344e-01 0.445 0 0
Mitochondrial biogenesis R-HSA-1592230 3.899870e-01 0.409 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 3.120687e-01 0.506 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 2.985196e-01 0.525 0 0
DNA Repair R-HSA-73894 2.868979e-01 0.542 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 3.646558e-01 0.438 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 3.646558e-01 0.438 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 3.646558e-01 0.438 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 3.646558e-01 0.438 0 0
Formation of definitive endoderm R-HSA-9823730 2.787654e-01 0.555 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 3.540489e-01 0.451 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 4.113328e-01 0.386 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 3.751572e-01 0.426 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.131313e-01 0.504 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 4.655398e-01 0.332 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 4.683311e-01 0.329 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 4.703805e-01 0.328 0 0
Adaptive Immune System R-HSA-1280218 2.986558e-01 0.525 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 4.154916e-01 0.381 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.592142e-01 0.586 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.720419e-01 0.429 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.696948e-01 0.328 0 0
Protein methylation R-HSA-8876725 2.808464e-01 0.552 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.542825e-01 0.343 0 0
Metabolism of RNA R-HSA-8953854 4.615031e-01 0.336 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 3.751572e-01 0.426 0 0
Platelet degranulation R-HSA-114608 3.566545e-01 0.448 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 4.080417e-01 0.389 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 4.703805e-01 0.328 0 0
Immune System R-HSA-168256 4.110649e-01 0.386 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 2.592142e-01 0.586 0 0
Formation of the Editosome R-HSA-75094 3.109443e-01 0.507 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 3.109443e-01 0.507 0 0
mRNA Editing: A to I Conversion R-HSA-75064 4.308958e-01 0.366 0 0
Influenza Virus Induced Apoptosis R-HSA-168277 4.308958e-01 0.366 0 0
C6 deamination of adenosine R-HSA-75102 4.308958e-01 0.366 0 0
Regulation of cortical dendrite branching R-HSA-8985801 4.308958e-01 0.366 0 0
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177 4.308958e-01 0.366 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 4.113328e-01 0.386 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 4.113328e-01 0.386 0 0
Metalloprotease DUBs R-HSA-5689901 2.985196e-01 0.525 0 0
FLT3 signaling in disease R-HSA-9682385 2.639980e-01 0.578 0 0
Mitochondrial calcium ion transport R-HSA-8949215 3.329887e-01 0.478 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 4.588162e-01 0.338 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 4.588162e-01 0.338 0 0
Intraflagellar transport R-HSA-5620924 2.696740e-01 0.569 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.880248e-01 0.411 0 0
Prolactin receptor signaling R-HSA-1170546 4.655398e-01 0.332 0 0
Smooth Muscle Contraction R-HSA-445355 3.593257e-01 0.445 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 4.258046e-01 0.371 0 0
Mitochondrial protein degradation R-HSA-9837999 3.964171e-01 0.402 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 4.707804e-01 0.327 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 3.998356e-01 0.398 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 3.100092e-01 0.509 0 0
GPVI-mediated activation cascade R-HSA-114604 4.031749e-01 0.395 0 0
Malate-aspartate shuttle R-HSA-9856872 2.501545e-01 0.602 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.808464e-01 0.552 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.329887e-01 0.478 0 0
Amine ligand-binding receptors R-HSA-375280 4.499794e-01 0.347 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 3.646558e-01 0.438 0 0
Hemostasis R-HSA-109582 3.429722e-01 0.465 0 0
Uptake and function of anthrax toxins R-HSA-5210891 3.751572e-01 0.426 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 4.588162e-01 0.338 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 3.131313e-01 0.504 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 3.604786e-01 0.443 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.354141e-01 0.474 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 4.707804e-01 0.327 0 0
Phospholipid metabolism R-HSA-1483257 4.833589e-01 0.316 0 0
Regulation of KIT signaling R-HSA-1433559 4.655398e-01 0.332 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 4.258046e-01 0.371 0 0
Inositol phosphate metabolism R-HSA-1483249 3.882998e-01 0.411 0 0
Ion channel transport R-HSA-983712 2.699443e-01 0.569 0 0
Stimuli-sensing channels R-HSA-2672351 2.556555e-01 0.592 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 3.109443e-01 0.507 0 0
DSCAM interactions R-HSA-376172 4.308958e-01 0.366 0 0
Tandem pore domain potassium channels R-HSA-1296346 2.778824e-01 0.556 0 0
Synthesis of PI R-HSA-1483226 3.159250e-01 0.500 0 0
Regulation of gene expression in beta cells R-HSA-210745 3.720419e-01 0.429 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.707230e-01 0.327 0 0
Inflammasomes R-HSA-622312 3.473447e-01 0.459 0 0
STING mediated induction of host immune responses R-HSA-1834941 4.377069e-01 0.359 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 4.420862e-01 0.354 0 0
MITF-M-dependent gene expression R-HSA-9856651 2.720847e-01 0.565 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 4.291415e-01 0.367 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 4.291415e-01 0.367 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 3.329887e-01 0.478 0 0
Tie2 Signaling R-HSA-210993 4.065944e-01 0.391 0 0
Interleukin-7 signaling R-HSA-1266695 4.427532e-01 0.354 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 4.308958e-01 0.366 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 4.113328e-01 0.386 0 0
Sodium/Proton exchangers R-HSA-425986 4.588162e-01 0.338 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.131313e-01 0.504 0 0
Growth hormone receptor signaling R-HSA-982772 3.880248e-01 0.411 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 3.640736e-01 0.439 0 0
HDL assembly R-HSA-8963896 2.501545e-01 0.602 0 0
Metal ion SLC transporters R-HSA-425410 2.696740e-01 0.569 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 3.109443e-01 0.507 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 4.113328e-01 0.386 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.913995e-01 0.309 0 0
Plasma lipoprotein assembly R-HSA-8963898 4.154916e-01 0.381 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.748850e-01 0.323 0 0
Insulin processing R-HSA-264876 4.962128e-01 0.304 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.008732e-01 0.300 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 5.008732e-01 0.300 0 0
Translesion synthesis by REV1 R-HSA-110312 5.008732e-01 0.300 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 5.008732e-01 0.300 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.008732e-01 0.300 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 5.008732e-01 0.300 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.008732e-01 0.300 0 0
Formation of the anterior neural plate R-HSA-9823739 5.008732e-01 0.300 0 0
Regulated proteolysis of p75NTR R-HSA-193692 5.039925e-01 0.298 0 0
MAPK1 (ERK2) activation R-HSA-112411 5.039925e-01 0.298 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 5.039925e-01 0.298 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 5.039925e-01 0.298 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 5.039925e-01 0.298 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 5.039925e-01 0.298 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 5.039925e-01 0.298 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 5.039925e-01 0.298 0 0
Adipogenesis R-HSA-9843745 5.042798e-01 0.297 0 0
Transcription of the HIV genome R-HSA-167172 5.051324e-01 0.297 0 0
TFAP2 (AP-2) family regulates transcription of other transcription factors R-HSA-8866906 5.057118e-01 0.296 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 5.057118e-01 0.296 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 5.057118e-01 0.296 0 0
Axonal growth stimulation R-HSA-209563 5.057118e-01 0.296 0 0
Defective GCLC causes HAGGSD R-HSA-5578999 5.057118e-01 0.296 0 0
MET activates PTPN11 R-HSA-8865999 5.057118e-01 0.296 0 0
Classical Kir channels R-HSA-1296053 5.057118e-01 0.296 0 0
Invadopodia formation R-HSA-8941237 5.057118e-01 0.296 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 5.057118e-01 0.296 0 0
Defective CYP1B1 causes Glaucoma R-HSA-5579000 5.057118e-01 0.296 0 0
Defective CYP7B1 causes SPG5A and CBAS3 R-HSA-5579013 5.057118e-01 0.296 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 5.057118e-01 0.296 0 0
MET interacts with TNS proteins R-HSA-8875513 5.057118e-01 0.296 0 0
Activation of BMF and translocation to mitochondria R-HSA-139910 5.057118e-01 0.296 0 0
Histamine receptors R-HSA-390650 5.057118e-01 0.296 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 5.057118e-01 0.296 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 5.093005e-01 0.293 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 5.117880e-01 0.291 0 0
Co-inhibition by PD-1 R-HSA-389948 5.141612e-01 0.289 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 5.146586e-01 0.288 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 5.180555e-01 0.286 0 0
SARS-CoV-2 Infection R-HSA-9694516 5.187548e-01 0.285 0 0
Pyroptosis R-HSA-5620971 5.222148e-01 0.282 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 5.222997e-01 0.282 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 5.275624e-01 0.278 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 5.275624e-01 0.278 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 5.275624e-01 0.278 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.275624e-01 0.278 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 5.275624e-01 0.278 0 0
Translesion synthesis by POLI R-HSA-5656121 5.349723e-01 0.272 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.349723e-01 0.272 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.349723e-01 0.272 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 5.349723e-01 0.272 0 0
Negative regulation of FLT3 R-HSA-9706369 5.349723e-01 0.272 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 5.361522e-01 0.271 0 0
PERK regulates gene expression R-HSA-381042 5.412606e-01 0.267 0 0
Binding and entry of HIV virion R-HSA-173107 5.466477e-01 0.262 0 0
MAPK3 (ERK1) activation R-HSA-110056 5.466477e-01 0.262 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 5.466477e-01 0.262 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 5.466477e-01 0.262 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 5.466477e-01 0.262 0 0
Arachidonate production from DAG R-HSA-426048 5.466477e-01 0.262 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 5.466477e-01 0.262 0 0
Receptor Mediated Mitophagy R-HSA-8934903 5.466477e-01 0.262 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 5.466477e-01 0.262 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 5.466477e-01 0.262 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 5.466477e-01 0.262 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.469762e-01 0.262 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 5.476200e-01 0.262 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 5.476200e-01 0.262 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.486530e-01 0.261 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.488123e-01 0.261 0 0
TCR signaling R-HSA-202403 5.509227e-01 0.259 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 5.559441e-01 0.255 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 5.559441e-01 0.255 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.560438e-01 0.255 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.560438e-01 0.255 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 5.639645e-01 0.249 0 0
Translesion synthesis by POLK R-HSA-5655862 5.677070e-01 0.246 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.677070e-01 0.246 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 5.677070e-01 0.246 0 0
Disorders of Developmental Biology R-HSA-9675151 5.677070e-01 0.246 0 0
Developmental Biology R-HSA-1266738 5.681851e-01 0.246 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 5.683644e-01 0.245 0 0
NADE modulates death signalling R-HSA-205025 5.706960e-01 0.244 0 0
TNFR1-mediated ceramide production R-HSA-5626978 5.706960e-01 0.244 0 0
HCN channels R-HSA-1296061 5.706960e-01 0.244 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 5.706960e-01 0.244 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 5.706960e-01 0.244 0 0
ATP sensitive Potassium channels R-HSA-1296025 5.706960e-01 0.244 0 0
Regulation of gap junction activity R-HSA-191650 5.706960e-01 0.244 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 5.706960e-01 0.244 0 0
Electric Transmission Across Gap Junctions R-HSA-112303 5.706960e-01 0.244 0 0
Transmission across Electrical Synapses R-HSA-112307 5.706960e-01 0.244 0 0
MDK and PTN in ALK signaling R-HSA-9851151 5.706960e-01 0.244 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 5.706960e-01 0.244 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 5.706960e-01 0.244 0 0
Dopamine receptors R-HSA-390651 5.706960e-01 0.244 0 0
Interleukin-38 signaling R-HSA-9007892 5.706960e-01 0.244 0 0
Signaling by FGFR R-HSA-190236 5.710657e-01 0.243 0 0
Regulation of RAS by GAPs R-HSA-5658442 5.711380e-01 0.243 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 5.725703e-01 0.242 0 0
Signaling by Insulin receptor R-HSA-74752 5.748874e-01 0.240 0 0
Integration of energy metabolism R-HSA-163685 5.773325e-01 0.239 0 0
Reproduction R-HSA-1474165 5.803405e-01 0.236 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 5.833845e-01 0.234 0 0
Interleukin receptor SHC signaling R-HSA-912526 5.833845e-01 0.234 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 5.833845e-01 0.234 0 0
Dual incision in TC-NER R-HSA-6782135 5.834745e-01 0.234 0 0
Signaling by MET R-HSA-6806834 5.836930e-01 0.234 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 5.866639e-01 0.232 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 5.866639e-01 0.232 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 5.866639e-01 0.232 0 0
FGFR2b ligand binding and activation R-HSA-190377 5.866639e-01 0.232 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 5.866639e-01 0.232 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 5.866639e-01 0.232 0 0
Formation of the posterior neural plate R-HSA-9832991 5.866639e-01 0.232 0 0
Interleukin-2 signaling R-HSA-9020558 5.866639e-01 0.232 0 0
Ionotropic activity of kainate receptors R-HSA-451306 5.866639e-01 0.232 0 0
PECAM1 interactions R-HSA-210990 5.866639e-01 0.232 0 0
Suppression of apoptosis R-HSA-9635465 5.866639e-01 0.232 0 0
Bicarbonate transporters R-HSA-425381 5.866639e-01 0.232 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 5.866639e-01 0.232 0 0
Budding and maturation of HIV virion R-HSA-162588 5.963713e-01 0.224 0 0
Cyclin D associated events in G1 R-HSA-69231 5.981071e-01 0.223 0 0
G1 Phase R-HSA-69236 5.981071e-01 0.223 0 0
Extension of Telomeres R-HSA-180786 6.012081e-01 0.221 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 6.012081e-01 0.221 0 0
Signaling by ERBB4 R-HSA-1236394 6.048197e-01 0.218 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 6.098169e-01 0.215 0 0
Complex III assembly R-HSA-9865881 6.098169e-01 0.215 0 0
Interleukin-6 family signaling R-HSA-6783589 6.098169e-01 0.215 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 6.142446e-01 0.212 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 6.160896e-01 0.210 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 6.177876e-01 0.209 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 6.177876e-01 0.209 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 6.177876e-01 0.209 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 6.205030e-01 0.207 0 0
rRNA processing R-HSA-72312 6.237028e-01 0.205 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 6.239977e-01 0.205 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 6.239977e-01 0.205 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 6.239977e-01 0.205 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 6.239977e-01 0.205 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 6.239977e-01 0.205 0 0
Integration of provirus R-HSA-162592 6.239977e-01 0.205 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 6.258477e-01 0.204 0 0
Regulation of PTEN stability and activity R-HSA-8948751 6.270080e-01 0.203 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 6.271400e-01 0.203 0 0
Defective CYP17A1 causes AH5 R-HSA-5579028 6.271400e-01 0.203 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 6.271400e-01 0.203 0 0
Defective F9 activation R-HSA-9673221 6.271400e-01 0.203 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 6.271400e-01 0.203 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 6.271400e-01 0.203 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 6.271400e-01 0.203 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.271400e-01 0.203 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 6.271400e-01 0.203 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 6.271400e-01 0.203 0 0
Activation of AKT2 R-HSA-165158 6.271400e-01 0.203 0 0
PTK6 Down-Regulation R-HSA-8849472 6.271400e-01 0.203 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 6.271400e-01 0.203 0 0
Activation of C3 and C5 R-HSA-174577 6.271400e-01 0.203 0 0
Trafficking of myristoylated proteins to the cilium R-HSA-5624138 6.271400e-01 0.203 0 0
Muscarinic acetylcholine receptors R-HSA-390648 6.271400e-01 0.203 0 0
Inositol transporters R-HSA-429593 6.271400e-01 0.203 0 0
Co-inhibition by BTLA R-HSA-9927353 6.271400e-01 0.203 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 6.271400e-01 0.203 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 6.275327e-01 0.202 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.287334e-01 0.202 0 0
GAB1 signalosome R-HSA-180292 6.287334e-01 0.202 0 0
FGFR1 ligand binding and activation R-HSA-190242 6.287334e-01 0.202 0 0
Nephron development R-HSA-9831926 6.287334e-01 0.202 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.287334e-01 0.202 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 6.288321e-01 0.201 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 6.351902e-01 0.197 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 6.351902e-01 0.197 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 6.351902e-01 0.197 0 0
G protein gated Potassium channels R-HSA-1296059 6.351902e-01 0.197 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 6.351902e-01 0.197 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 6.351902e-01 0.197 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.369303e-01 0.196 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.369303e-01 0.196 0 0
G-protein beta:gamma signalling R-HSA-397795 6.420338e-01 0.192 0 0
Cardiogenesis R-HSA-9733709 6.420338e-01 0.192 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 6.482740e-01 0.188 0 0
Attenuation phase R-HSA-3371568 6.488551e-01 0.188 0 0
Interleukin-2 family signaling R-HSA-451927 6.488551e-01 0.188 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 6.519282e-01 0.186 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 6.520583e-01 0.186 0 0
Mitochondrial protein import R-HSA-1268020 6.520583e-01 0.186 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 6.520583e-01 0.186 0 0
Signaling by PDGF R-HSA-186797 6.520583e-01 0.186 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 6.555104e-01 0.183 0 0
Regulation of signaling by CBL R-HSA-912631 6.569229e-01 0.182 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 6.569229e-01 0.182 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 6.569229e-01 0.182 0 0
Translesion Synthesis by POLH R-HSA-110320 6.569229e-01 0.182 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.569229e-01 0.182 0 0
Maturation of nucleoprotein R-HSA-9694631 6.569229e-01 0.182 0 0
Polymerase switching R-HSA-69091 6.586627e-01 0.181 0 0
Leading Strand Synthesis R-HSA-69109 6.586627e-01 0.181 0 0
IRAK1 recruits IKK complex R-HSA-937039 6.586627e-01 0.181 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 6.586627e-01 0.181 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 6.586627e-01 0.181 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 6.586627e-01 0.181 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 6.586627e-01 0.181 0 0
MET activates RAS signaling R-HSA-8851805 6.586627e-01 0.181 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 6.586627e-01 0.181 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 6.586627e-01 0.181 0 0
Disorders of Nervous System Development R-HSA-9697154 6.586627e-01 0.181 0 0
Pervasive developmental disorders R-HSA-9005895 6.586627e-01 0.181 0 0
Interleukin-15 signaling R-HSA-8983432 6.586627e-01 0.181 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 6.586627e-01 0.181 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 6.594682e-01 0.181 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 6.619499e-01 0.179 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 6.636145e-01 0.178 0 0
Miscellaneous transport and binding events R-HSA-5223345 6.636145e-01 0.178 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 6.684268e-01 0.175 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 6.684268e-01 0.175 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 6.736713e-01 0.172 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 6.741464e-01 0.171 0 0
Plus-strand DNA synthesis R-HSA-164525 6.761658e-01 0.170 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 6.761658e-01 0.170 0 0
PKB-mediated events R-HSA-109703 6.761658e-01 0.170 0 0
PDE3B signalling R-HSA-165160 6.761658e-01 0.170 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 6.761658e-01 0.170 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 6.761658e-01 0.170 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 6.761658e-01 0.170 0 0
Signaling by RNF43 mutants R-HSA-5340588 6.761658e-01 0.170 0 0
NGF-independant TRKA activation R-HSA-187024 6.761658e-01 0.170 0 0
Phosphorylation of Emi1 R-HSA-176417 6.761658e-01 0.170 0 0
Ceramide signalling R-HSA-193681 6.761658e-01 0.170 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 6.761658e-01 0.170 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 6.761658e-01 0.170 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 6.761658e-01 0.170 0 0
Acetylcholine inhibits contraction of outer hair cells R-HSA-9667769 6.761658e-01 0.170 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 6.761658e-01 0.170 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 6.761658e-01 0.170 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 6.761658e-01 0.170 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 6.786695e-01 0.168 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 6.786695e-01 0.168 0 0
Sensory processing of sound R-HSA-9659379 6.799158e-01 0.168 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 6.826279e-01 0.166 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 6.826279e-01 0.166 0 0
Signaling by FGFR3 in disease R-HSA-5655332 6.826279e-01 0.166 0 0
Acyl chain remodelling of PI R-HSA-1482922 6.835358e-01 0.165 0 0
Negative regulation of MET activity R-HSA-6807004 6.835358e-01 0.165 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 6.843298e-01 0.165 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 6.843298e-01 0.165 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.854810e-01 0.164 0 0
Intra-Golgi traffic R-HSA-6811438 6.872919e-01 0.163 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 6.884237e-01 0.162 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 6.888922e-01 0.162 0 0
FGFR2c ligand binding and activation R-HSA-190375 6.907153e-01 0.161 0 0
FGFR4 ligand binding and activation R-HSA-190322 6.907153e-01 0.161 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 6.907153e-01 0.161 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 6.907153e-01 0.161 0 0
Processing of SMDT1 R-HSA-8949664 6.907153e-01 0.161 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 6.907153e-01 0.161 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 6.907153e-01 0.161 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 6.907153e-01 0.161 0 0
Maturation of nucleoprotein R-HSA-9683610 6.907153e-01 0.161 0 0
FGFR3 mutant receptor activation R-HSA-2033514 6.907153e-01 0.161 0 0
Switching of origins to a post-replicative state R-HSA-69052 7.032240e-01 0.153 0 0
Oncogene Induced Senescence R-HSA-2559585 7.041658e-01 0.152 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.046578e-01 0.152 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 7.046578e-01 0.152 0 0
Formation of the Early Elongation Complex R-HSA-113418 7.046578e-01 0.152 0 0
Lagging Strand Synthesis R-HSA-69186 7.085763e-01 0.150 0 0
Early Phase of HIV Life Cycle R-HSA-162594 7.085763e-01 0.150 0 0
Signalling to RAS R-HSA-167044 7.085763e-01 0.150 0 0
Basigin interactions R-HSA-210991 7.085763e-01 0.150 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 7.085763e-01 0.150 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.106600e-01 0.148 0 0
Signaling by FGFR in disease R-HSA-1226099 7.171339e-01 0.144 0 0
Erythropoietin activates STAT5 R-HSA-9027283 7.187477e-01 0.143 0 0
Uncoating of the HIV Virion R-HSA-162585 7.187477e-01 0.143 0 0
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors R-HSA-629587 7.187477e-01 0.143 0 0
Hydrolysis of LPE R-HSA-1483152 7.187477e-01 0.143 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 7.187477e-01 0.143 0 0
G2/M DNA replication checkpoint R-HSA-69478 7.187477e-01 0.143 0 0
Neurofascin interactions R-HSA-447043 7.187477e-01 0.143 0 0
Abacavir transmembrane transport R-HSA-2161517 7.187477e-01 0.143 0 0
Signaling by LTK in cancer R-HSA-9842640 7.187477e-01 0.143 0 0
Leukotriene receptors R-HSA-391906 7.187477e-01 0.143 0 0
Nef and signal transduction R-HSA-164944 7.187477e-01 0.143 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 7.202429e-01 0.143 0 0
Removal of the Flap Intermediate R-HSA-69166 7.202429e-01 0.143 0 0
Retrograde neurotrophin signalling R-HSA-177504 7.202429e-01 0.143 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 7.202429e-01 0.143 0 0
Hydrolysis of LPC R-HSA-1483115 7.202429e-01 0.143 0 0
NRIF signals cell death from the nucleus R-HSA-205043 7.202429e-01 0.143 0 0
FGFR3c ligand binding and activation R-HSA-190372 7.202429e-01 0.143 0 0
Signaling by FGFR4 in disease R-HSA-5655291 7.202429e-01 0.143 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 7.202429e-01 0.143 0 0
Physiological factors R-HSA-5578768 7.202429e-01 0.143 0 0
P2Y receptors R-HSA-417957 7.202429e-01 0.143 0 0
Zinc transporters R-HSA-435354 7.202429e-01 0.143 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 7.231156e-01 0.141 0 0
RUNX2 regulates bone development R-HSA-8941326 7.231156e-01 0.141 0 0
Meiotic recombination R-HSA-912446 7.238680e-01 0.140 0 0
DNA Replication Pre-Initiation R-HSA-69002 7.240242e-01 0.140 0 0
Triglyceride metabolism R-HSA-8979227 7.256707e-01 0.139 0 0
Regulation of beta-cell development R-HSA-186712 7.256707e-01 0.139 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 7.306160e-01 0.136 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 7.314304e-01 0.136 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 7.320647e-01 0.135 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 7.320647e-01 0.135 0 0
Assembly Of The HIV Virion R-HSA-175474 7.320647e-01 0.135 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 7.394162e-01 0.131 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.394162e-01 0.131 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 7.395130e-01 0.131 0 0
RMTs methylate histone arginines R-HSA-3214858 7.395393e-01 0.131 0 0
GABA receptor activation R-HSA-977443 7.402601e-01 0.131 0 0
Degradation of DVL R-HSA-4641258 7.411785e-01 0.130 0 0
Collagen chain trimerization R-HSA-8948216 7.411785e-01 0.130 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 7.414340e-01 0.130 0 0
Clathrin-mediated endocytosis R-HSA-8856828 7.431986e-01 0.129 0 0
DAP12 signaling R-HSA-2424491 7.453331e-01 0.128 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.453331e-01 0.128 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 7.458883e-01 0.127 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 7.473554e-01 0.126 0 0
Erythropoietin activates RAS R-HSA-9027284 7.473554e-01 0.126 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.473554e-01 0.126 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 7.473554e-01 0.126 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 7.473554e-01 0.126 0 0
Processive synthesis on the lagging strand R-HSA-69183 7.473554e-01 0.126 0 0
Telomere C-strand synthesis initiation R-HSA-174430 7.473554e-01 0.126 0 0
FGFR3 ligand binding and activation R-HSA-190239 7.473554e-01 0.126 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 7.473554e-01 0.126 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 7.473554e-01 0.126 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 7.473554e-01 0.126 0 0
Biotin transport and metabolism R-HSA-196780 7.473554e-01 0.126 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 7.540343e-01 0.123 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.540343e-01 0.123 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 7.540343e-01 0.123 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 7.540343e-01 0.123 0 0
Fructose metabolism R-HSA-5652084 7.540343e-01 0.123 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 7.540343e-01 0.123 0 0
Signaling by KIT in disease R-HSA-9669938 7.540343e-01 0.123 0 0
LDL clearance R-HSA-8964038 7.540343e-01 0.123 0 0
Viral Messenger RNA Synthesis R-HSA-168325 7.543047e-01 0.122 0 0
Collagen degradation R-HSA-1442490 7.543047e-01 0.122 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.543047e-01 0.122 0 0
Aquaporin-mediated transport R-HSA-445717 7.543047e-01 0.122 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.543400e-01 0.122 0 0
Amino acids regulate mTORC1 R-HSA-9639288 7.543400e-01 0.122 0 0
Fanconi Anemia Pathway R-HSA-6783310 7.554931e-01 0.122 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 7.557326e-01 0.122 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 7.557326e-01 0.122 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 7.557326e-01 0.122 0 0
Disinhibition of SNARE formation R-HSA-114516 7.557326e-01 0.122 0 0
FGFR3b ligand binding and activation R-HSA-190371 7.557326e-01 0.122 0 0
Recycling of eIF2:GDP R-HSA-72731 7.557326e-01 0.122 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 7.557326e-01 0.122 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 7.557326e-01 0.122 0 0
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974 7.557326e-01 0.122 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 7.557326e-01 0.122 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 7.557326e-01 0.122 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 7.557326e-01 0.122 0 0
VLDL clearance R-HSA-8964046 7.557326e-01 0.122 0 0
Activation of TRKA receptors R-HSA-187015 7.557326e-01 0.122 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 7.557326e-01 0.122 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 7.557326e-01 0.122 0 0
Maturation of replicase proteins R-HSA-9694301 7.557326e-01 0.122 0 0
MET promotes cell motility R-HSA-8875878 7.583595e-01 0.120 0 0
Regulation of insulin secretion R-HSA-422356 7.619138e-01 0.118 0 0
Nucleotide Excision Repair R-HSA-5696398 7.641570e-01 0.117 0 0
tRNA processing in the nucleus R-HSA-6784531 7.678047e-01 0.115 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 7.707199e-01 0.113 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 7.707199e-01 0.113 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 7.707199e-01 0.113 0 0
Killing mechanisms R-HSA-9664420 7.721773e-01 0.112 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 7.721773e-01 0.112 0 0
Fructose catabolism R-HSA-70350 7.721773e-01 0.112 0 0
Differentiation of T cells R-HSA-9945266 7.721773e-01 0.112 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 7.721773e-01 0.112 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 7.721773e-01 0.112 0 0
Serotonin and melatonin biosynthesis R-HSA-209931 7.721773e-01 0.112 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.745287e-01 0.111 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 7.745287e-01 0.111 0 0
Interleukin-20 family signaling R-HSA-8854691 7.745287e-01 0.111 0 0
Stabilization of p53 R-HSA-69541 7.746686e-01 0.111 0 0
PPARA activates gene expression R-HSA-1989781 7.814963e-01 0.107 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 7.815860e-01 0.107 0 0
Assembly of the pre-replicative complex R-HSA-68867 7.817111e-01 0.107 0 0
Signaling by NOTCH3 R-HSA-9012852 7.823230e-01 0.107 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 7.852273e-01 0.105 0 0
Reverse Transcription of HIV RNA R-HSA-162589 7.878558e-01 0.104 0 0
Minus-strand DNA synthesis R-HSA-164516 7.878558e-01 0.104 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 7.878558e-01 0.104 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 7.878558e-01 0.104 0 0
phospho-PLA2 pathway R-HSA-111995 7.878558e-01 0.104 0 0
Formation of annular gap junctions R-HSA-196025 7.878558e-01 0.104 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 7.878558e-01 0.104 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 7.878558e-01 0.104 0 0
Highly calcium permeable nicotinic acetylcholine receptors R-HSA-629597 7.878558e-01 0.104 0 0
MET receptor recycling R-HSA-8875656 7.878558e-01 0.104 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 7.878558e-01 0.104 0 0
Fructose biosynthesis R-HSA-5652227 7.878558e-01 0.104 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 7.878558e-01 0.104 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 7.878558e-01 0.104 0 0
TGFBR3 PTM regulation R-HSA-9839383 7.878558e-01 0.104 0 0
Alpha-defensins R-HSA-1462054 7.878558e-01 0.104 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 7.901199e-01 0.102 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 7.901199e-01 0.102 0 0
Generation of second messenger molecules R-HSA-202433 7.901199e-01 0.102 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.935998e-01 0.100 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 7.935998e-01 0.100 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 7.940298e-01 0.100 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 7.948419e-01 0.100 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 7.948419e-01 0.100 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 7.948419e-01 0.100 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 7.948419e-01 0.100 0 0
Galactose catabolism R-HSA-70370 7.948419e-01 0.100 0 0
tRNA modification in the mitochondrion R-HSA-6787450 7.948419e-01 0.100 0 0
Synthesis of PG R-HSA-1483148 7.948419e-01 0.100 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 7.975791e-01 0.098 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 7.981124e-01 0.098 0 0
Nuclear RNA decay R-HSA-9930044 7.981124e-01 0.098 0 0
Signaling by NOTCH R-HSA-157118 8.019549e-01 0.096 0 0
Interferon alpha/beta signaling R-HSA-909733 8.043289e-01 0.095 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 8.043945e-01 0.095 0 0
Cellular response to hypoxia R-HSA-1234174 8.050681e-01 0.094 0 0
HCMV Early Events R-HSA-9609690 8.080640e-01 0.093 0 0
Interferon gamma signaling R-HSA-877300 8.128213e-01 0.090 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.136134e-01 0.090 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.154874e-01 0.089 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 8.154874e-01 0.089 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 8.154874e-01 0.089 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 8.154874e-01 0.089 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 8.157562e-01 0.088 0 0
Gap junction degradation R-HSA-190873 8.157562e-01 0.088 0 0
p75NTR regulates axonogenesis R-HSA-193697 8.157562e-01 0.088 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 8.157562e-01 0.088 0 0
Interleukin-21 signaling R-HSA-9020958 8.157562e-01 0.088 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 8.157562e-01 0.088 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 8.157562e-01 0.088 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 8.157562e-01 0.088 0 0
Cellular response to mitochondrial stress R-HSA-9840373 8.157562e-01 0.088 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 8.157562e-01 0.088 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 8.161042e-01 0.088 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 8.161919e-01 0.088 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.185242e-01 0.087 0 0
HIV Transcription Initiation R-HSA-167161 8.185242e-01 0.087 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.185242e-01 0.087 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.185242e-01 0.087 0 0
Downstream TCR signaling R-HSA-202424 8.217750e-01 0.085 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.245515e-01 0.084 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.246564e-01 0.084 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 8.277079e-01 0.082 0 0
Mitophagy R-HSA-5205647 8.281245e-01 0.082 0 0
Signal amplification R-HSA-392518 8.281245e-01 0.082 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 8.281245e-01 0.082 0 0
RSV-host interactions R-HSA-9833110 8.296684e-01 0.081 0 0
Telomere Maintenance R-HSA-157579 8.301542e-01 0.081 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 8.315218e-01 0.080 0 0
Activation of GABAB receptors R-HSA-991365 8.315218e-01 0.080 0 0
GABA B receptor activation R-HSA-977444 8.315218e-01 0.080 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 8.342527e-01 0.079 0 0
Activated point mutants of FGFR2 R-HSA-2033519 8.342527e-01 0.079 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 8.342527e-01 0.079 0 0
Mismatch Repair R-HSA-5358508 8.342527e-01 0.079 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 8.342527e-01 0.079 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 8.342527e-01 0.079 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.363116e-01 0.078 0 0
Epigenetic regulation of gene expression R-HSA-212165 8.398006e-01 0.076 0 0
2-LTR circle formation R-HSA-164843 8.399886e-01 0.076 0 0
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors R-HSA-629594 8.399886e-01 0.076 0 0
TET1,2,3 and TDG demethylate DNA R-HSA-5221030 8.399886e-01 0.076 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 8.399886e-01 0.076 0 0
CASP4 inflammasome assembly R-HSA-9948001 8.399886e-01 0.076 0 0
Formation of intermediate mesoderm R-HSA-9761174 8.399886e-01 0.076 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 8.399886e-01 0.076 0 0
Interleukin-27 signaling R-HSA-9020956 8.399886e-01 0.076 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 8.399886e-01 0.076 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 8.399886e-01 0.076 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 8.399886e-01 0.076 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 8.399886e-01 0.076 0 0
Serotonin receptors R-HSA-390666 8.399886e-01 0.076 0 0
Cristae formation R-HSA-8949613 8.428724e-01 0.074 0 0
Packaging Of Telomere Ends R-HSA-171306 8.428724e-01 0.074 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 8.428724e-01 0.074 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 8.428724e-01 0.074 0 0
Signaling by BMP R-HSA-201451 8.428724e-01 0.074 0 0
Cell-Cell communication R-HSA-1500931 8.428749e-01 0.074 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.437500e-01 0.074 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 8.437500e-01 0.074 0 0
Selenoamino acid metabolism R-HSA-2408522 8.473012e-01 0.072 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 8.474279e-01 0.072 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 8.485293e-01 0.071 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 8.505344e-01 0.070 0 0
Other interleukin signaling R-HSA-449836 8.512752e-01 0.070 0 0
Crosslinking of collagen fibrils R-HSA-2243919 8.512752e-01 0.070 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 8.512752e-01 0.070 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 8.512752e-01 0.070 0 0
Chromosome Maintenance R-HSA-73886 8.524668e-01 0.069 0 0
PCP/CE pathway R-HSA-4086400 8.532382e-01 0.069 0 0
Synthesis of DNA R-HSA-69239 8.538277e-01 0.069 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.543321e-01 0.068 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 8.552363e-01 0.068 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 8.568292e-01 0.067 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 8.568657e-01 0.067 0 0
Potential therapeutics for SARS R-HSA-9679191 8.589920e-01 0.066 0 0
FGFRL1 modulation of FGFR1 signaling R-HSA-5658623 8.610351e-01 0.065 0 0
vRNP Assembly R-HSA-192905 8.610351e-01 0.065 0 0
vRNA Synthesis R-HSA-192814 8.610351e-01 0.065 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 8.610351e-01 0.065 0 0
Transport of RCbl within the body R-HSA-9758890 8.610351e-01 0.065 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 8.610351e-01 0.065 0 0
Inorganic anion exchange by SLC26 transporters R-HSA-427601 8.610351e-01 0.065 0 0
LGI-ADAM interactions R-HSA-5682910 8.610351e-01 0.065 0 0
Chylomicron assembly R-HSA-8963888 8.610351e-01 0.065 0 0
Prostanoid ligand receptors R-HSA-391908 8.610351e-01 0.065 0 0
SARS-CoV Infections R-HSA-9679506 8.635065e-01 0.064 0 0
Collagen formation R-HSA-1474290 8.645527e-01 0.063 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 8.660092e-01 0.062 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 8.661104e-01 0.062 0 0
Cleavage of the damaged purine R-HSA-110331 8.661104e-01 0.062 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 8.666886e-01 0.062 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 8.666886e-01 0.062 0 0
Glycogen synthesis R-HSA-3322077 8.666886e-01 0.062 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 8.666886e-01 0.062 0 0
Pregnenolone biosynthesis R-HSA-196108 8.666886e-01 0.062 0 0
Protein hydroxylation R-HSA-9629569 8.666886e-01 0.062 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 8.666886e-01 0.062 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 8.678118e-01 0.062 0 0
mRNA Capping R-HSA-72086 8.697551e-01 0.061 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 8.697551e-01 0.061 0 0
Depurination R-HSA-73927 8.770612e-01 0.057 0 0
Elastic fibre formation R-HSA-1566948 8.770612e-01 0.057 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.770612e-01 0.057 0 0
HDACs deacetylate histones R-HSA-3214815 8.771227e-01 0.057 0 0
Presynaptic nicotinic acetylcholine receptors R-HSA-622323 8.793144e-01 0.056 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 8.793144e-01 0.056 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 8.793144e-01 0.056 0 0
Plasmalogen biosynthesis R-HSA-75896 8.793144e-01 0.056 0 0
ERKs are inactivated R-HSA-202670 8.793144e-01 0.056 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 8.793144e-01 0.056 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 8.793144e-01 0.056 0 0
FGFR2 ligand binding and activation R-HSA-190241 8.806216e-01 0.055 0 0
ERK/MAPK targets R-HSA-198753 8.806216e-01 0.055 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 8.806216e-01 0.055 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 8.806216e-01 0.055 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.816076e-01 0.055 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 8.816076e-01 0.055 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.816076e-01 0.055 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 8.855338e-01 0.053 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 8.858765e-01 0.053 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 8.872272e-01 0.052 0 0
Plasma lipoprotein clearance R-HSA-8964043 8.872272e-01 0.052 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.924893e-01 0.049 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 8.931969e-01 0.049 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 8.931969e-01 0.049 0 0
Scavenging by Class F Receptors R-HSA-3000484 8.951901e-01 0.048 0 0
GRB2 events in EGFR signaling R-HSA-179812 8.951901e-01 0.048 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.951901e-01 0.048 0 0
Interleukin-35 Signalling R-HSA-8984722 8.951901e-01 0.048 0 0
Proline catabolism R-HSA-70688 8.951901e-01 0.048 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 8.951901e-01 0.048 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 8.951901e-01 0.048 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 8.951901e-01 0.048 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 8.951901e-01 0.048 0 0
Estrogen biosynthesis R-HSA-193144 8.951901e-01 0.048 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 8.951901e-01 0.048 0 0
DNA strand elongation R-HSA-69190 9.024646e-01 0.045 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.025654e-01 0.045 0 0
Cellular response to chemical stress R-HSA-9711123 9.030463e-01 0.044 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.045306e-01 0.044 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 9.045306e-01 0.044 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 9.045306e-01 0.044 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.045306e-01 0.044 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.053740e-01 0.043 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.053740e-01 0.043 0 0
Acetylcholine binding and downstream events R-HSA-181431 9.089783e-01 0.041 0 0
Postsynaptic nicotinic acetylcholine receptors R-HSA-622327 9.089783e-01 0.041 0 0
Adenylate cyclase activating pathway R-HSA-170660 9.089783e-01 0.041 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 9.089783e-01 0.041 0 0
Chylomicron remodeling R-HSA-8963901 9.089783e-01 0.041 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 9.089783e-01 0.041 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 9.089783e-01 0.041 0 0
Mtb iron assimilation by chelation R-HSA-1222449 9.089783e-01 0.041 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 9.089783e-01 0.041 0 0
CD28 dependent Vav1 pathway R-HSA-389359 9.089783e-01 0.041 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 9.089783e-01 0.041 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.090260e-01 0.041 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.091213e-01 0.041 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.134531e-01 0.039 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 9.147315e-01 0.039 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 9.147315e-01 0.039 0 0
Carnitine shuttle R-HSA-200425 9.147315e-01 0.039 0 0
Synthesis of UDP-N-acetyl-glucosamine R-HSA-446210 9.147315e-01 0.039 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 9.157826e-01 0.038 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.157826e-01 0.038 0 0
G alpha (q) signalling events R-HSA-416476 9.167812e-01 0.038 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.199431e-01 0.036 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.199431e-01 0.036 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 9.199431e-01 0.036 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 9.208833e-01 0.036 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.208833e-01 0.036 0 0
Depyrimidination R-HSA-73928 9.208833e-01 0.036 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 9.209533e-01 0.036 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 9.209533e-01 0.036 0 0
Transport of fatty acids R-HSA-804914 9.209533e-01 0.036 0 0
Non-canonical inflammasome activation R-HSA-9686114 9.209533e-01 0.036 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 9.209533e-01 0.036 0 0
Signal regulatory protein family interactions R-HSA-391160 9.209533e-01 0.036 0 0
Acyl chain remodeling of CL R-HSA-1482798 9.209533e-01 0.036 0 0
HCMV Infection R-HSA-9609646 9.231227e-01 0.035 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.239016e-01 0.034 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.239016e-01 0.034 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 9.239016e-01 0.034 0 0
Orc1 removal from chromatin R-HSA-68949 9.239664e-01 0.034 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 9.239664e-01 0.034 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.242659e-01 0.034 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.275640e-01 0.033 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.275640e-01 0.033 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.275640e-01 0.033 0 0
Signaling by NOTCH2 R-HSA-1980145 9.275640e-01 0.033 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.275640e-01 0.033 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.277487e-01 0.033 0 0
Defective pyroptosis R-HSA-9710421 9.277487e-01 0.033 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 9.313534e-01 0.031 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 9.313534e-01 0.031 0 0
G beta:gamma signalling through BTK R-HSA-8964315 9.313534e-01 0.031 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 9.313534e-01 0.031 0 0
p38MAPK events R-HSA-171007 9.313534e-01 0.031 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 9.313534e-01 0.031 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 9.313534e-01 0.031 0 0
DNA Damage Reversal R-HSA-73942 9.313534e-01 0.031 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.314310e-01 0.031 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 9.321355e-01 0.031 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 9.321355e-01 0.031 0 0
Tight junction interactions R-HSA-420029 9.321355e-01 0.031 0 0
Acyl chain remodelling of PS R-HSA-1482801 9.321355e-01 0.031 0 0
Formation of the nephric duct R-HSA-9830364 9.321355e-01 0.031 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 9.323844e-01 0.030 0 0
Viral Infection Pathways R-HSA-9824446 9.338394e-01 0.030 0 0
DAP12 interactions R-HSA-2172127 9.340719e-01 0.030 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.343147e-01 0.030 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.343147e-01 0.030 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.345130e-01 0.029 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.345130e-01 0.029 0 0
Cell junction organization R-HSA-446728 9.348088e-01 0.029 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.358102e-01 0.029 0 0
GPCR downstream signalling R-HSA-388396 9.362442e-01 0.029 0 0
Base Excision Repair R-HSA-73884 9.369643e-01 0.028 0 0
Developmental Cell Lineages R-HSA-9734767 9.376405e-01 0.028 0 0
Urea cycle R-HSA-70635 9.395206e-01 0.027 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.398891e-01 0.027 0 0
Nucleosome assembly R-HSA-774815 9.398891e-01 0.027 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 9.398891e-01 0.027 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.398891e-01 0.027 0 0
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-HSA-2142816 9.403857e-01 0.027 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 9.403857e-01 0.027 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 9.403857e-01 0.027 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 9.403857e-01 0.027 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 9.403857e-01 0.027 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 9.403857e-01 0.027 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 9.403857e-01 0.027 0 0
Synthesis of wybutosine at G37 of tRNA(Phe) R-HSA-6782861 9.403857e-01 0.027 0 0
Attachment and Entry R-HSA-9678110 9.403857e-01 0.027 0 0
Atorvastatin ADME R-HSA-9754706 9.403857e-01 0.027 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.408420e-01 0.026 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 9.408420e-01 0.026 0 0
RNA Polymerase III Transcription R-HSA-74158 9.408420e-01 0.026 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 9.408420e-01 0.026 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 9.412013e-01 0.026 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.412665e-01 0.026 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.436551e-01 0.025 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 9.452349e-01 0.024 0 0
Gene Silencing by RNA R-HSA-211000 9.459043e-01 0.024 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 9.461378e-01 0.024 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.461378e-01 0.024 0 0
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane R-HSA-83936 9.461378e-01 0.024 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.461831e-01 0.024 0 0
Protein ubiquitination R-HSA-8852135 9.462269e-01 0.024 0 0
DNA Replication R-HSA-69306 9.466889e-01 0.024 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 9.482300e-01 0.023 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 9.482300e-01 0.023 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.482300e-01 0.023 0 0
Phase 2 - plateau phase R-HSA-5576893 9.482300e-01 0.023 0 0
Formation of xylulose-5-phosphate R-HSA-5661270 9.482300e-01 0.023 0 0
Coenzyme A biosynthesis R-HSA-196783 9.482300e-01 0.023 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 9.482300e-01 0.023 0 0
Synthesis of PC R-HSA-1483191 9.501423e-01 0.022 0 0
UCH proteinases R-HSA-5689603 9.502457e-01 0.022 0 0
Synthesis of PA R-HSA-1483166 9.504862e-01 0.022 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.518327e-01 0.021 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 9.520613e-01 0.021 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.520613e-01 0.021 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 9.520613e-01 0.021 0 0
G alpha (s) signalling events R-HSA-418555 9.524493e-01 0.021 0 0
Gluconeogenesis R-HSA-70263 9.546426e-01 0.020 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 9.546426e-01 0.020 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.546551e-01 0.020 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 9.550425e-01 0.020 0 0
Glycogen storage diseases R-HSA-3229121 9.550425e-01 0.020 0 0
Catecholamine biosynthesis R-HSA-209905 9.550425e-01 0.020 0 0
Pentose phosphate pathway R-HSA-71336 9.565834e-01 0.019 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.565834e-01 0.019 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 9.565834e-01 0.019 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.565834e-01 0.019 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.573590e-01 0.019 0 0
Degradation of CDH1 R-HSA-9766229 9.587657e-01 0.018 0 0
Gastrulation R-HSA-9758941 9.589034e-01 0.018 0 0
Pyruvate metabolism R-HSA-70268 9.595381e-01 0.018 0 0
Parasitic Infection Pathways R-HSA-9824443 9.595437e-01 0.018 0 0
Leishmania infection R-HSA-9658195 9.595437e-01 0.018 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 9.608921e-01 0.017 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.608921e-01 0.017 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 9.608921e-01 0.017 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.608921e-01 0.017 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 9.608921e-01 0.017 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.609589e-01 0.017 0 0
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670 9.609589e-01 0.017 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.609589e-01 0.017 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.620929e-01 0.017 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.638383e-01 0.016 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.647964e-01 0.016 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.647964e-01 0.016 0 0
Maturation of spike protein R-HSA-9694548 9.647964e-01 0.016 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.653115e-01 0.015 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 9.656383e-01 0.015 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.659904e-01 0.015 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.659904e-01 0.015 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.660970e-01 0.015 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.660970e-01 0.015 0 0
Diseases of hemostasis R-HSA-9671793 9.660970e-01 0.015 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.660970e-01 0.015 0 0
HDL remodeling R-HSA-8964058 9.660970e-01 0.015 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.663198e-01 0.015 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 9.663198e-01 0.015 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.663198e-01 0.015 0 0
Cargo concentration in the ER R-HSA-5694530 9.663198e-01 0.015 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.663198e-01 0.015 0 0
Protein localization R-HSA-9609507 9.676357e-01 0.014 0 0
Neurotransmitter release cycle R-HSA-112310 9.678739e-01 0.014 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.683311e-01 0.014 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.683311e-01 0.014 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.693791e-01 0.014 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.700909e-01 0.013 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 9.705592e-01 0.013 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 9.705592e-01 0.013 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.705592e-01 0.013 0 0
Signaling by NODAL R-HSA-1181150 9.705592e-01 0.013 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 9.720215e-01 0.012 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.734532e-01 0.012 0 0
Signaling by NOTCH4 R-HSA-9013694 9.734555e-01 0.012 0 0
ABC-family proteins mediated transport R-HSA-382556 9.736715e-01 0.012 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 9.738837e-01 0.011 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 9.738837e-01 0.011 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.744180e-01 0.011 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 9.744343e-01 0.011 0 0
G-protein activation R-HSA-202040 9.744343e-01 0.011 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.744343e-01 0.011 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.744343e-01 0.011 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 9.744343e-01 0.011 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 9.744343e-01 0.011 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.756725e-01 0.011 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 9.764487e-01 0.010 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.764487e-01 0.010 0 0
Proteasome assembly R-HSA-9907900 9.770277e-01 0.010 0 0
Androgen biosynthesis R-HSA-193048 9.777995e-01 0.010 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.777995e-01 0.010 0 0
Serine metabolism R-HSA-977347 9.777995e-01 0.010 0 0
Glucocorticoid biosynthesis R-HSA-194002 9.777995e-01 0.010 0 0
Glutathione synthesis and recycling R-HSA-174403 9.777995e-01 0.010 0 0
Attachment and Entry R-HSA-9694614 9.777995e-01 0.010 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.780802e-01 0.010 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 9.791158e-01 0.009 0 0
eNOS activation R-HSA-203615 9.791158e-01 0.009 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 9.791158e-01 0.009 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.792180e-01 0.009 0 0
Somitogenesis R-HSA-9824272 9.793826e-01 0.009 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.793826e-01 0.009 0 0
Translation of Structural Proteins R-HSA-9694635 9.796008e-01 0.009 0 0
Kidney development R-HSA-9830369 9.800380e-01 0.009 0 0
Innate Immune System R-HSA-168249 9.802650e-01 0.009 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 9.807219e-01 0.008 0 0
Ethanol oxidation R-HSA-71384 9.807219e-01 0.008 0 0
Regulation of CDH1 Function R-HSA-9764561 9.812006e-01 0.008 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 9.812247e-01 0.008 0 0
RNA Polymerase I Transcription R-HSA-73864 9.813357e-01 0.008 0 0
Integrin cell surface interactions R-HSA-216083 9.813357e-01 0.008 0 0
Cholesterol biosynthesis R-HSA-191273 9.813357e-01 0.008 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.814891e-01 0.008 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.814891e-01 0.008 0 0
Regulation of Apoptosis R-HSA-169911 9.814891e-01 0.008 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.815061e-01 0.008 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.815061e-01 0.008 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.829321e-01 0.007 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.832598e-01 0.007 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.832598e-01 0.007 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.832598e-01 0.007 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.835996e-01 0.007 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.840281e-01 0.007 0 0
ER-Phagosome pathway R-HSA-1236974 9.842447e-01 0.007 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.851426e-01 0.007 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 9.854637e-01 0.006 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.854637e-01 0.006 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.854637e-01 0.006 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.854637e-01 0.006 0 0
Degradation of AXIN R-HSA-4641257 9.854754e-01 0.006 0 0
Metabolism of folate and pterines R-HSA-196757 9.854754e-01 0.006 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 9.861292e-01 0.006 0 0
Signaling by GPCR R-HSA-372790 9.861358e-01 0.006 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 9.863443e-01 0.006 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.869827e-01 0.006 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.873775e-01 0.006 0 0
Beta-oxidation of pristanoyl-CoA R-HSA-389887 9.873775e-01 0.006 0 0
Laminin interactions R-HSA-3000157 9.873775e-01 0.006 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.873775e-01 0.006 0 0
Endogenous sterols R-HSA-211976 9.874790e-01 0.005 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.881256e-01 0.005 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.887031e-01 0.005 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.888722e-01 0.005 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.890395e-01 0.005 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.890395e-01 0.005 0 0
Abacavir ADME R-HSA-2161522 9.890395e-01 0.005 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.890395e-01 0.005 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 9.891687e-01 0.005 0 0
The phototransduction cascade R-HSA-2514856 9.893407e-01 0.005 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 9.904664e-01 0.004 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 9.904828e-01 0.004 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.904828e-01 0.004 0 0
Triglyceride biosynthesis R-HSA-75109 9.904828e-01 0.004 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 9.904828e-01 0.004 0 0
Synthesis of PE R-HSA-1483213 9.904828e-01 0.004 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.904828e-01 0.004 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 9.916007e-01 0.004 0 0
Prednisone ADME R-HSA-9757110 9.917360e-01 0.004 0 0
Insulin receptor recycling R-HSA-77387 9.917360e-01 0.004 0 0
Pyrimidine salvage R-HSA-73614 9.917360e-01 0.004 0 0
Adherens junctions interactions R-HSA-418990 9.920723e-01 0.003 0 0
Translation of Structural Proteins R-HSA-9683701 9.921309e-01 0.003 0 0
DNA methylation R-HSA-5334118 9.928243e-01 0.003 0 0
Thyroxine biosynthesis R-HSA-209968 9.928243e-01 0.003 0 0
Glucagon-type ligand receptors R-HSA-420092 9.928243e-01 0.003 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.930193e-01 0.003 0 0
Leishmania phagocytosis R-HSA-9664417 9.930607e-01 0.003 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.930607e-01 0.003 0 0
Parasite infection R-HSA-9664407 9.930607e-01 0.003 0 0
ABC transporter disorders R-HSA-5619084 9.931073e-01 0.003 0 0
G alpha (z) signalling events R-HSA-418597 9.931967e-01 0.003 0 0
Metabolism of steroid hormones R-HSA-196071 9.932936e-01 0.003 0 0
Neurotransmitter clearance R-HSA-112311 9.937693e-01 0.003 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 9.943537e-01 0.002 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.945900e-01 0.002 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.947532e-01 0.002 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.951212e-01 0.002 0 0
COPII-mediated vesicle transport R-HSA-204005 9.951212e-01 0.002 0 0
Metabolism of steroids R-HSA-8957322 9.954151e-01 0.002 0 0
ECM proteoglycans R-HSA-3000178 9.956157e-01 0.002 0 0
Recycling of bile acids and salts R-HSA-159418 9.959213e-01 0.002 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.961537e-01 0.002 0 0
HCMV Late Events R-HSA-9610379 9.963506e-01 0.002 0 0
Heme degradation R-HSA-189483 9.964586e-01 0.002 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.968258e-01 0.001 0 0
RA biosynthesis pathway R-HSA-5365859 9.969251e-01 0.001 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.969251e-01 0.001 0 0
Hyaluronan metabolism R-HSA-2142845 9.969251e-01 0.001 0 0
Cell-cell junction organization R-HSA-421270 9.969493e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.970791e-01 0.001 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.970969e-01 0.001 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.973302e-01 0.001 0 0
tRNA processing R-HSA-72306 9.973815e-01 0.001 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.974902e-01 0.001 0 0
Glycosphingolipid transport R-HSA-9845576 9.976820e-01 0.001 0 0
Interleukin-10 signaling R-HSA-6783783 9.979470e-01 0.001 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.979874e-01 0.001 0 0
NCAM1 interactions R-HSA-419037 9.979874e-01 0.001 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.979874e-01 0.001 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.979874e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.980787e-01 0.001 0 0
Neddylation R-HSA-8951664 9.980934e-01 0.001 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.981605e-01 0.001 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.982526e-01 0.001 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.982942e-01 0.001 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.984829e-01 0.001 0 0
RAS processing R-HSA-9648002 9.984829e-01 0.001 0 0
Amyloid fiber formation R-HSA-977225 9.985247e-01 0.001 0 0
Regulation of endogenous retroelements R-HSA-9842860 9.985772e-01 0.001 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.988564e-01 0.000 0 0
Formation of the cornified envelope R-HSA-6809371 9.989114e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.989353e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.989460e-01 0.000 0 0
Dectin-2 family R-HSA-5621480 9.989462e-01 0.000 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.990071e-01 0.000 0 0
Translation R-HSA-72766 9.990307e-01 0.000 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.990543e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.991074e-01 0.000 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.991380e-01 0.000 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.991380e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.991397e-01 0.000 0 0
Peroxisomal protein import R-HSA-9033241 9.991838e-01 0.000 0 0
Defensins R-HSA-1461973 9.992516e-01 0.000 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 9.992545e-01 0.000 0 0
Glutathione conjugation R-HSA-156590 9.992819e-01 0.000 0 0
Metabolism of polyamines R-HSA-351202 9.992819e-01 0.000 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.993503e-01 0.000 0 0
Surfactant metabolism R-HSA-5683826 9.993503e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.994323e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.995387e-01 0.000 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.995748e-01 0.000 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.996796e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.997084e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.997084e-01 0.000 0 0
SLC transporter disorders R-HSA-5619102 9.997178e-01 0.000 0 0
Azathioprine ADME R-HSA-9748787 9.997218e-01 0.000 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.997218e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.997438e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.997789e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.998023e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.998079e-01 0.000 0 0
Nucleotide biosynthesis R-HSA-8956320 9.998180e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.998264e-01 0.000 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.998448e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.998514e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.998514e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.998611e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.998661e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.998783e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.998809e-01 0.000 0 0
Digestion R-HSA-8935690 9.998809e-01 0.000 0 0
Iron uptake and transport R-HSA-917937 9.998969e-01 0.000 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.999221e-01 0.000 0 0
tRNA Aminoacylation R-HSA-379724 9.999324e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.999413e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.999530e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.999558e-01 0.000 0 0
Digestion and absorption R-HSA-8963743 9.999558e-01 0.000 0 0
Post-translational protein modification R-HSA-597592 9.999572e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.999616e-01 0.000 0 0
Glycosphingolipid biosynthesis R-HSA-9840309 9.999616e-01 0.000 0 0
Xenobiotics R-HSA-211981 9.999616e-01 0.000 0 0
Latent infection - Other responses of Mtb to phagocytosis R-HSA-1222499 9.999667e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999683e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.999784e-01 0.000 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.999858e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.999858e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999874e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.999876e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999930e-01 0.000 0 0
Disease R-HSA-1643685 9.999941e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.999943e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.999947e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999952e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999956e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.999957e-01 0.000 0 0
Regulation of Complement cascade R-HSA-977606 9.999957e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999964e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999967e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999974e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999977e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999983e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999984e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999985e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999989e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999989e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999993e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999995e-01 0.000 0 0
Complement cascade R-HSA-166658 9.999998e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999998e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999999e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999999e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999999e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 1.000000e+00 0.000 0 0
Initial triggering of complement R-HSA-166663 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
O-linked glycosylation R-HSA-5173105 1.000000e+00 0.000 0 0
Mitochondrial translation R-HSA-5368287 1.000000e+00 0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 1.000000e+00 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 1.000000e+00 0.000 0 0
Nucleotide catabolism R-HSA-8956319 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Sensory perception of taste R-HSA-9717189 1.000000e+00 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Diseases of glycosylation R-HSA-3781865 1.000000e+00 0.000 0 0
Metabolism of nucleotides R-HSA-15869 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 9.287016e-13 12.032 0 0
Cellular responses to stimuli R-HSA-8953897 4.121570e-11 10.385 0 0
Cell Cycle R-HSA-1640170 1.221753e-10 9.913 0 0
Cellular responses to stress R-HSA-2262752 3.197322e-10 9.495 0 0
Nervous system development R-HSA-9675108 7.386465e-10 9.132 0 0
Cell Cycle Checkpoints R-HSA-69620 7.676283e-10 9.115 0 0
Cell Cycle, Mitotic R-HSA-69278 1.371475e-09 8.863 0 0
M Phase R-HSA-68886 1.708677e-09 8.767 0 0
Axon guidance R-HSA-422475 1.629193e-09 8.788 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.144265e-09 8.383 0 0
Apoptosis R-HSA-109581 4.588285e-09 8.338 0 0
G2/M Checkpoints R-HSA-69481 1.042616e-08 7.982 0 0
Signaling by RAF1 mutants R-HSA-9656223 2.409190e-08 7.618 0 0
Signaling by RAS mutants R-HSA-6802949 2.715374e-08 7.566 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.715374e-08 7.566 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.715374e-08 7.566 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.715374e-08 7.566 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.239564e-08 7.650 0 0
Apoptotic execution phase R-HSA-75153 2.715374e-08 7.566 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 4.350178e-08 7.361 0 0
Membrane Trafficking R-HSA-199991 4.391021e-08 7.357 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 5.258700e-08 7.279 0 0
Oncogenic MAPK signaling R-HSA-6802957 5.943005e-08 7.226 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 6.899973e-08 7.161 0 0
Programmed Cell Death R-HSA-5357801 7.578239e-08 7.120 0 0
Eukaryotic Translation Initiation R-HSA-72613 9.247926e-08 7.034 0 0
Cap-dependent Translation Initiation R-HSA-72737 9.247926e-08 7.034 0 0
HSF1-dependent transactivation R-HSA-3371571 1.220574e-07 6.913 0 0
Cell-Cell communication R-HSA-1500931 1.411236e-07 6.850 0 0
Cellular response to heat stress R-HSA-3371556 2.209358e-07 6.656 0 0
Signal Transduction R-HSA-162582 2.885461e-07 6.540 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.306881e-07 6.481 0 0
Signaling by ALK in cancer R-HSA-9700206 3.306881e-07 6.481 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 3.164579e-07 6.500 0 0
Interleukin-12 signaling R-HSA-9020591 3.218934e-07 6.492 0 0
Eukaryotic Translation Elongation R-HSA-156842 3.863302e-07 6.413 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 3.951061e-07 6.403 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 4.538547e-07 6.343 0 0
DNA Double Strand Break Response R-HSA-5693606 5.065240e-07 6.295 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 5.655227e-07 6.248 0 0
Attenuation phase R-HSA-3371568 1.141883e-06 5.942 0 0
Kinesins R-HSA-983189 1.245981e-06 5.904 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.387319e-06 5.858 0 0
HSF1 activation R-HSA-3371511 1.473910e-06 5.832 0 0
MAP2K and MAPK activation R-HSA-5674135 2.026960e-06 5.693 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.301641e-06 5.638 0 0
Formation of a pool of free 40S subunits R-HSA-72689 2.434039e-06 5.614 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.919240e-06 5.535 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 3.311566e-06 5.480 0 0
Chaperone Mediated Autophagy R-HSA-9613829 3.328955e-06 5.478 0 0
RAF activation R-HSA-5673000 3.485009e-06 5.458 0 0
Interleukin-12 family signaling R-HSA-447115 3.549889e-06 5.450 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 5.882205e-06 5.230 0 0
Mitotic Prometaphase R-HSA-68877 5.759038e-06 5.240 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 6.082174e-06 5.216 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 6.691232e-06 5.174 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 8.190268e-06 5.087 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 8.230081e-06 5.085 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 8.510326e-06 5.070 0 0
Striated Muscle Contraction R-HSA-390522 1.102763e-05 4.958 0 0
Ribosome-associated quality control R-HSA-9948299 1.126662e-05 4.948 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.271674e-05 4.896 0 0
Peptide chain elongation R-HSA-156902 1.231666e-05 4.910 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.409111e-05 4.851 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.483636e-05 4.829 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.483636e-05 4.829 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 1.555992e-05 4.808 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 1.555992e-05 4.808 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.685492e-05 4.773 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.833691e-05 4.737 0 0
Cell junction organization R-HSA-446728 1.923253e-05 4.716 0 0
Meiotic recombination R-HSA-912446 2.380702e-05 4.623 0 0
Separation of Sister Chromatids R-HSA-2467813 2.382318e-05 4.623 0 0
DNA Replication Pre-Initiation R-HSA-69002 2.594841e-05 4.586 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 2.594841e-05 4.586 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.637404e-05 4.579 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.641219e-05 4.578 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 2.951014e-05 4.530 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.207992e-05 4.494 0 0
Assembly of the pre-replicative complex R-HSA-68867 3.239541e-05 4.490 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 3.200996e-05 4.495 0 0
Mitotic Anaphase R-HSA-68882 3.297023e-05 4.482 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 3.639820e-05 4.439 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.629311e-05 4.440 0 0
Vesicle-mediated transport R-HSA-5653656 3.488588e-05 4.457 0 0
Signaling by ROBO receptors R-HSA-376176 3.570796e-05 4.447 0 0
Late endosomal microautophagy R-HSA-9615710 4.568772e-05 4.340 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 4.604087e-05 4.337 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 4.629981e-05 4.334 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.604087e-05 4.337 0 0
Homology Directed Repair R-HSA-5693538 4.670341e-05 4.331 0 0
Autophagy R-HSA-9612973 4.794573e-05 4.319 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 4.894675e-05 4.310 0 0
Meiosis R-HSA-1500620 4.981343e-05 4.303 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 5.418091e-05 4.266 0 0
HDACs deacetylate histones R-HSA-3214815 5.458887e-05 4.263 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 5.468701e-05 4.262 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 5.775952e-05 4.238 0 0
Mitotic Prophase R-HSA-68875 6.043592e-05 4.219 0 0
Aggrephagy R-HSA-9646399 6.738888e-05 4.171 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 6.639744e-05 4.178 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 6.699166e-05 4.174 0 0
Cellular Senescence R-HSA-2559583 6.802784e-05 4.167 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 6.858385e-05 4.164 0 0
Nucleosome assembly R-HSA-774815 7.427860e-05 4.129 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 7.427860e-05 4.129 0 0
Protein ubiquitination R-HSA-8852135 7.591654e-05 4.120 0 0
DNA Double-Strand Break Repair R-HSA-5693532 7.583676e-05 4.120 0 0
ISG15 antiviral mechanism R-HSA-1169408 7.591654e-05 4.120 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.619967e-05 4.064 0 0
L1CAM interactions R-HSA-373760 8.675875e-05 4.062 0 0
TCF dependent signaling in response to WNT R-HSA-201681 9.178067e-05 4.037 0 0
Muscle contraction R-HSA-397014 9.246430e-05 4.034 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.464131e-05 4.024 0 0
Packaging Of Telomere Ends R-HSA-171306 1.073280e-04 3.969 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.073280e-04 3.969 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.071151e-04 3.970 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.126295e-04 3.948 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 1.208623e-04 3.918 0 0
Meiotic synapsis R-HSA-1221632 1.162105e-04 3.935 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.220643e-04 3.913 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.208623e-04 3.918 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.197645e-04 3.922 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.245253e-04 3.905 0 0
Influenza Infection R-HSA-168255 1.281657e-04 3.892 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 1.301393e-04 3.886 0 0
Eukaryotic Translation Termination R-HSA-72764 1.301393e-04 3.886 0 0
Translation initiation complex formation R-HSA-72649 1.404096e-04 3.853 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.420412e-04 3.848 0 0
Ub-specific processing proteases R-HSA-5689880 1.472093e-04 3.832 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.476366e-04 3.831 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.663362e-04 3.779 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.548488e-04 3.810 0 0
Signaling by MET R-HSA-6806834 1.669286e-04 3.777 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.551552e-04 3.809 0 0
DNA methylation R-HSA-5334118 1.832584e-04 3.737 0 0
Metabolism of RNA R-HSA-8953854 1.843843e-04 3.734 0 0
Nephrin family interactions R-HSA-373753 1.864507e-04 3.729 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.908709e-04 3.719 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.011591e-04 3.696 0 0
Signaling by EGFR R-HSA-177929 2.023241e-04 3.694 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 2.262747e-04 3.645 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 2.345229e-04 3.630 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 2.244164e-04 3.649 0 0
Selective autophagy R-HSA-9663891 2.370659e-04 3.625 0 0
Diseases of programmed cell death R-HSA-9645723 2.370659e-04 3.625 0 0
Regulation of CDH1 Function R-HSA-9764561 2.413603e-04 3.617 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.536773e-04 3.596 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.536773e-04 3.596 0 0
Deubiquitination R-HSA-5688426 2.549824e-04 3.593 0 0
Cellular response to starvation R-HSA-9711097 2.714154e-04 3.566 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 2.754118e-04 3.560 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 2.867219e-04 3.543 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 2.867832e-04 3.542 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 2.986242e-04 3.525 0 0
Josephin domain DUBs R-HSA-5689877 3.001245e-04 3.523 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 3.009391e-04 3.522 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 3.275882e-04 3.485 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 3.524815e-04 3.453 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.251877e-04 3.488 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.510816e-04 3.455 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.524815e-04 3.453 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 3.805467e-04 3.420 0 0
Signaling by ERBB2 R-HSA-1227986 4.002648e-04 3.398 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 4.128582e-04 3.384 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 4.274107e-04 3.369 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 4.497826e-04 3.347 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 4.589396e-04 3.338 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 4.647725e-04 3.333 0 0
PECAM1 interactions R-HSA-210990 4.647725e-04 3.333 0 0
ChREBP activates metabolic gene expression R-HSA-163765 4.647725e-04 3.333 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.772603e-04 3.321 0 0
Defective pyroptosis R-HSA-9710421 5.174560e-04 3.286 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.755358e-04 3.240 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.755358e-04 3.240 0 0
MAPK family signaling cascades R-HSA-5683057 5.456131e-04 3.263 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 5.755358e-04 3.240 0 0
Signaling by WNT R-HSA-195721 5.590504e-04 3.253 0 0
Cell-extracellular matrix interactions R-HSA-446353 5.755358e-04 3.240 0 0
Adherens junctions interactions R-HSA-418990 5.683432e-04 3.245 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 5.774390e-04 3.238 0 0
Regulation of signaling by CBL R-HSA-912631 6.073321e-04 3.217 0 0
Cytokine Signaling in Immune system R-HSA-1280215 6.115265e-04 3.214 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.301612e-04 3.201 0 0
SARS-CoV-2-host interactions R-HSA-9705683 6.680074e-04 3.175 0 0
Selenocysteine synthesis R-HSA-2408557 6.694271e-04 3.174 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 6.876658e-04 3.163 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 7.335383e-04 3.135 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 7.335383e-04 3.135 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 7.418681e-04 3.130 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 7.506727e-04 3.125 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 7.506727e-04 3.125 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 7.579714e-04 3.120 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 7.527282e-04 3.123 0 0
Viral mRNA Translation R-HSA-192823 8.434481e-04 3.074 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 7.506727e-04 3.125 0 0
Macroautophagy R-HSA-1632852 8.499227e-04 3.071 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 8.523092e-04 3.069 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 8.900683e-04 3.051 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 8.900683e-04 3.051 0 0
mRNA Splicing - Major Pathway R-HSA-72163 9.454274e-04 3.024 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.006111e-03 2.997 0 0
Signaling by Interleukins R-HSA-449147 1.015963e-03 2.993 0 0
Recycling pathway of L1 R-HSA-437239 1.056112e-03 2.976 0 0
Viral Infection Pathways R-HSA-9824446 1.056259e-03 2.976 0 0
Protein folding R-HSA-391251 1.084167e-03 2.965 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.087239e-03 2.964 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.090638e-03 2.962 0 0
FLT3 signaling in disease R-HSA-9682385 1.095953e-03 2.960 0 0
Signaling by EGFR in Cancer R-HSA-1643713 1.222097e-03 2.913 0 0
Post NMDA receptor activation events R-HSA-438064 1.224909e-03 2.912 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.308372e-03 2.883 0 0
Cleavage of the damaged purine R-HSA-110331 1.326553e-03 2.877 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.344287e-03 2.872 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 1.366115e-03 2.865 0 0
Gap junction trafficking and regulation R-HSA-157858 1.466894e-03 2.834 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.418292e-03 2.848 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.548962e-03 2.810 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.546744e-03 2.811 0 0
Depurination R-HSA-73927 1.595861e-03 2.797 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.619572e-03 2.791 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.670981e-03 2.777 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.744377e-03 2.758 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.744377e-03 2.758 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.744377e-03 2.758 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.744377e-03 2.758 0 0
Signaling by NTRKs R-HSA-166520 1.752303e-03 2.756 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.895452e-03 2.722 0 0
Cell-cell junction organization R-HSA-421270 1.912858e-03 2.718 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 1.951672e-03 2.710 0 0
RNA Polymerase I Transcription R-HSA-73864 1.988743e-03 2.701 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.000702e-03 2.699 0 0
HCMV Early Events R-HSA-9609690 2.025691e-03 2.693 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.130280e-03 2.672 0 0
mRNA Splicing R-HSA-72172 2.173148e-03 2.663 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.225639e-03 2.653 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.225639e-03 2.653 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 2.326680e-03 2.633 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 2.513606e-03 2.600 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 2.628514e-03 2.580 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.750323e-03 2.561 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.840680e-03 2.547 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.936354e-03 2.532 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.536884e-03 2.596 0 0
Chaperonin-mediated protein folding R-HSA-390466 2.790502e-03 2.554 0 0
Interferon Signaling R-HSA-913531 2.746814e-03 2.561 0 0
DNA Replication R-HSA-69306 2.662441e-03 2.575 0 0
Signaling by FGFR2 R-HSA-5654738 2.529086e-03 2.597 0 0
HATs acetylate histones R-HSA-3214847 2.629804e-03 2.580 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 2.685245e-03 2.571 0 0
Activation of BH3-only proteins R-HSA-114452 2.840680e-03 2.547 0 0
Co-inhibition by PD-1 R-HSA-389948 2.705521e-03 2.568 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 2.628514e-03 2.580 0 0
SARS-CoV-1 Infection R-HSA-9678108 2.524475e-03 2.598 0 0
DNA Repair R-HSA-73894 3.027641e-03 2.519 0 0
HCMV Infection R-HSA-9609646 3.046870e-03 2.516 0 0
Translation R-HSA-72766 3.108142e-03 2.507 0 0
G2/M Transition R-HSA-69275 3.153524e-03 2.501 0 0
Negative regulation of MET activity R-HSA-6807004 3.160419e-03 2.500 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 3.187039e-03 2.497 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 3.238887e-03 2.490 0 0
Neutrophil degranulation R-HSA-6798695 3.357187e-03 2.474 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.437250e-03 2.464 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.561674e-03 2.448 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.638327e-03 2.439 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 3.645023e-03 2.438 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 3.700995e-03 2.432 0 0
Depyrimidination R-HSA-73928 3.700995e-03 2.432 0 0
DNA Damage Bypass R-HSA-73893 3.941713e-03 2.404 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 3.986153e-03 2.399 0 0
Metalloprotease DUBs R-HSA-5689901 4.167929e-03 2.380 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 4.430109e-03 2.354 0 0
Type I hemidesmosome assembly R-HSA-446107 4.430109e-03 2.354 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 4.430109e-03 2.354 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 4.430109e-03 2.354 0 0
Reproduction R-HSA-1474165 4.454457e-03 2.351 0 0
Regulation of TP53 Activity R-HSA-5633007 4.593095e-03 2.338 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 4.649528e-03 2.333 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 4.649528e-03 2.333 0 0
Platelet activation, signaling and aggregation R-HSA-76002 4.687000e-03 2.329 0 0
rRNA processing R-HSA-72312 4.702513e-03 2.328 0 0
p75NTR recruits signalling complexes R-HSA-209543 4.781501e-03 2.320 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 4.804929e-03 2.318 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 4.849515e-03 2.314 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.926696e-03 2.307 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 4.969048e-03 2.304 0 0
Assembly Of The HIV Virion R-HSA-175474 4.969048e-03 2.304 0 0
Gap junction trafficking R-HSA-190828 5.005410e-03 2.301 0 0
Interaction between L1 and Ankyrins R-HSA-445095 5.062961e-03 2.296 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 5.761935e-03 2.239 0 0
mRNA 3'-end processing R-HSA-72187 5.954325e-03 2.225 0 0
PKR-mediated signaling R-HSA-9833482 5.675951e-03 2.246 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 5.452884e-03 2.263 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.675951e-03 2.246 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 6.338006e-03 2.198 0 0
GP1b-IX-V activation signalling R-HSA-430116 6.338006e-03 2.198 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 6.338006e-03 2.198 0 0
Amyloid fiber formation R-HSA-977225 6.310904e-03 2.200 0 0
Gene Silencing by RNA R-HSA-211000 6.260461e-03 2.203 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 6.353815e-03 2.197 0 0
Glycogen metabolism R-HSA-8982491 6.353815e-03 2.197 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 6.357797e-03 2.197 0 0
Adaptive Immune System R-HSA-1280218 6.608987e-03 2.180 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.701406e-03 2.174 0 0
Smooth Muscle Contraction R-HSA-445355 6.782674e-03 2.169 0 0
Dual Incision in GG-NER R-HSA-5696400 6.880673e-03 2.162 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 6.880673e-03 2.162 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 6.938301e-03 2.159 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 6.938301e-03 2.159 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 6.938301e-03 2.159 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 6.938301e-03 2.159 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 7.259188e-03 2.139 0 0
GAB1 signalosome R-HSA-180292 7.259188e-03 2.139 0 0
Transport of connexons to the plasma membrane R-HSA-190872 7.259188e-03 2.139 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 7.259188e-03 2.139 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 7.293753e-03 2.137 0 0
FLT3 Signaling R-HSA-9607240 7.367463e-03 2.133 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 7.492826e-03 2.125 0 0
Maturation of protein E R-HSA-9683683 7.682037e-03 2.115 0 0
Maturation of protein E R-HSA-9694493 7.682037e-03 2.115 0 0
MHC class II antigen presentation R-HSA-2132295 7.703654e-03 2.113 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 9.026508e-03 2.044 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 9.026508e-03 2.044 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.624605e-03 2.017 0 0
Translesion Synthesis by POLH R-HSA-110320 9.026508e-03 2.044 0 0
COPI-mediated anterograde transport R-HSA-6807878 8.451754e-03 2.073 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 8.281185e-03 2.082 0 0
Opioid Signalling R-HSA-111885 8.686178e-03 2.061 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 8.281185e-03 2.082 0 0
Semaphorin interactions R-HSA-373755 9.624605e-03 2.017 0 0
Regulation of TP53 Degradation R-HSA-6804757 9.387094e-03 2.027 0 0
Ion homeostasis R-HSA-5578775 9.826180e-03 2.008 0 0
Regulation of KIT signaling R-HSA-1433559 8.281185e-03 2.082 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 9.624605e-03 2.017 0 0
Signaling by PTK6 R-HSA-8848021 9.624605e-03 2.017 0 0
Signaling by NOTCH3 R-HSA-9012852 8.712227e-03 2.060 0 0
Unfolded Protein Response (UPR) R-HSA-381119 9.721274e-03 2.012 0 0
Interleukin-37 signaling R-HSA-9008059 8.657917e-03 2.063 0 0
Budding and maturation of HIV virion R-HSA-162588 1.020723e-02 1.991 0 0
ESR-mediated signaling R-HSA-8939211 1.033197e-02 1.986 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.059010e-02 1.975 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.059010e-02 1.975 0 0
p75NTR signals via NF-kB R-HSA-193639 1.059010e-02 1.975 0 0
EPH-Ephrin signaling R-HSA-2682334 1.076571e-02 1.968 0 0
Long-term potentiation R-HSA-9620244 1.084395e-02 1.965 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.087593e-02 1.964 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.104828e-02 1.957 0 0
Co-inhibition by CTLA4 R-HSA-389513 1.109007e-02 1.955 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.109007e-02 1.955 0 0
Signaling by FGFR4 R-HSA-5654743 1.117607e-02 1.952 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.132428e-02 1.946 0 0
Nef and signal transduction R-HSA-164944 1.142915e-02 1.942 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.142938e-02 1.942 0 0
HCMV Late Events R-HSA-9610379 1.171212e-02 1.931 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 1.175317e-02 1.930 0 0
Glycolysis R-HSA-70171 1.201985e-02 1.920 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.208952e-02 1.918 0 0
Signaling by NOTCH R-HSA-157118 1.216862e-02 1.915 0 0
Cilium Assembly R-HSA-5617833 1.221925e-02 1.913 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.224326e-02 1.912 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.253725e-02 1.902 0 0
Negative regulation of FLT3 R-HSA-9706369 1.332163e-02 1.875 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.347556e-02 1.870 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.391962e-02 1.856 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.401180e-02 1.854 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.438263e-02 1.842 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.438263e-02 1.842 0 0
Signaling by FGFR3 R-HSA-5654741 1.444843e-02 1.840 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.458695e-02 1.836 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.501725e-02 1.823 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 1.599306e-02 1.796 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 1.599306e-02 1.796 0 0
MECP2 regulates transcription factors R-HSA-9022707 1.618417e-02 1.791 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.618417e-02 1.791 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.537613e-02 1.813 0 0
Signaling by GSK3beta mutants R-HSA-5339716 1.537613e-02 1.813 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 1.967720e-02 1.706 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 1.967720e-02 1.706 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 1.967720e-02 1.706 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 1.967720e-02 1.706 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 1.967720e-02 1.706 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.019063e-02 1.695 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.019063e-02 1.695 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.620789e-02 1.790 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.620789e-02 1.790 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 1.620789e-02 1.790 0 0
FGFR2 alternative splicing R-HSA-6803529 1.931083e-02 1.714 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 1.521285e-02 1.818 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.521285e-02 1.818 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 1.521285e-02 1.818 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.611162e-02 1.793 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.642355e-02 1.785 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.715140e-02 1.766 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 1.867137e-02 1.729 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 1.854639e-02 1.732 0 0
Gap junction assembly R-HSA-190861 1.854639e-02 1.732 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.537613e-02 1.813 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.651092e-02 1.782 0 0
VLDLR internalisation and degradation R-HSA-8866427 1.967720e-02 1.706 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.782054e-02 1.749 0 0
tRNA processing in the nucleus R-HSA-6784531 1.901439e-02 1.721 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 1.620789e-02 1.790 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.669077e-02 1.778 0 0
Regulation of PTEN localization R-HSA-8948747 1.618417e-02 1.791 0 0
IRAK1 recruits IKK complex R-HSA-937039 1.967720e-02 1.706 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 1.967720e-02 1.706 0 0
Host Interactions of HIV factors R-HSA-162909 1.535106e-02 1.814 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.521285e-02 1.818 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 1.931083e-02 1.714 0 0
Signaling by FGFR R-HSA-190236 1.949991e-02 1.710 0 0
Signaling by Hippo R-HSA-2028269 2.019063e-02 1.695 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.782151e-02 1.749 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 1.620789e-02 1.790 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.785686e-02 1.748 0 0
Platelet degranulation R-HSA-114608 2.035777e-02 1.691 0 0
Regulation of gap junction activity R-HSA-191650 2.037547e-02 1.691 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.037547e-02 1.691 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.037547e-02 1.691 0 0
Co-stimulation by CD28 R-HSA-389356 2.064519e-02 1.685 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.064519e-02 1.685 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 2.073403e-02 1.683 0 0
Termination of translesion DNA synthesis R-HSA-5656169 2.073403e-02 1.683 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 2.073403e-02 1.683 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 2.073403e-02 1.683 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.102560e-02 1.677 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.102560e-02 1.677 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.123765e-02 1.673 0 0
Oncogene Induced Senescence R-HSA-2559585 2.123765e-02 1.673 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 2.202057e-02 1.657 0 0
Modulation by Mtb of host immune system R-HSA-9637628 2.202057e-02 1.657 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.212337e-02 1.655 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 2.230994e-02 1.652 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 2.235475e-02 1.651 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.270396e-02 1.644 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.280681e-02 1.642 0 0
Ion transport by P-type ATPases R-HSA-936837 2.319156e-02 1.635 0 0
Signaling by TGFB family members R-HSA-9006936 2.391301e-02 1.621 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.397010e-02 1.620 0 0
G1/S-Specific Transcription R-HSA-69205 2.419862e-02 1.616 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 2.419862e-02 1.616 0 0
Ephrin signaling R-HSA-3928664 2.439049e-02 1.613 0 0
Platelet sensitization by LDL R-HSA-432142 2.439049e-02 1.613 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 2.469894e-02 1.607 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 2.469894e-02 1.607 0 0
Immune System R-HSA-168256 2.474067e-02 1.607 0 0
Regulation of RAS by GAPs R-HSA-5658442 2.574239e-02 1.589 0 0
Interferon alpha/beta signaling R-HSA-909733 2.583515e-02 1.588 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.617244e-02 1.582 0 0
Signaling by SCF-KIT R-HSA-1433557 2.676555e-02 1.572 0 0
Dual incision in TC-NER R-HSA-6782135 2.709962e-02 1.567 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.744192e-02 1.562 0 0
EGFR downregulation R-HSA-182971 2.754453e-02 1.560 0 0
Death Receptor Signaling R-HSA-73887 2.769901e-02 1.558 0 0
AURKA Activation by TPX2 R-HSA-8854518 2.801334e-02 1.553 0 0
Signaling by ERBB4 R-HSA-1236394 2.857309e-02 1.544 0 0
ARMS-mediated activation R-HSA-170984 2.899165e-02 1.538 0 0
Gap junction degradation R-HSA-190873 2.899165e-02 1.538 0 0
Rap1 signalling R-HSA-392517 2.913691e-02 1.536 0 0
Chromatin organization R-HSA-4839726 2.938537e-02 1.532 0 0
RNA Polymerase II Transcription R-HSA-73857 2.957035e-02 1.529 0 0
G1 Phase R-HSA-69236 2.994852e-02 1.524 0 0
Cyclin D associated events in G1 R-HSA-69231 2.994852e-02 1.524 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.994852e-02 1.524 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 3.047656e-02 1.516 0 0
NRIF signals cell death from the nucleus R-HSA-205043 3.047656e-02 1.516 0 0
G1/S Transition R-HSA-69206 3.090472e-02 1.510 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.097947e-02 1.509 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 3.124122e-02 1.505 0 0
Base Excision Repair R-HSA-73884 3.124122e-02 1.505 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.162805e-02 1.500 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 3.206507e-02 1.494 0 0
Chromatin modifying enzymes R-HSA-3247509 3.336154e-02 1.477 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 3.336367e-02 1.477 0 0
Oligomerization of connexins into connexons R-HSA-190704 3.381586e-02 1.471 0 0
Transport of connexins along the secretory pathway R-HSA-190827 3.381586e-02 1.471 0 0
Manipulation of host energy metabolism R-HSA-9636667 3.381586e-02 1.471 0 0
Glycogen synthesis R-HSA-3322077 3.445265e-02 1.463 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.482238e-02 1.458 0 0
Hemostasis R-HSA-109582 3.482565e-02 1.458 0 0
Integrin signaling R-HSA-354192 3.576593e-02 1.447 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 3.576593e-02 1.447 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.576593e-02 1.447 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 3.585132e-02 1.445 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 3.703755e-02 1.431 0 0
Translesion synthesis by REV1 R-HSA-110312 3.703755e-02 1.431 0 0
DCC mediated attractive signaling R-HSA-418885 3.703755e-02 1.431 0 0
Protein methylation R-HSA-8876725 3.703755e-02 1.431 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.713097e-02 1.430 0 0
Pexophagy R-HSA-9664873 3.713097e-02 1.430 0 0
Developmental Biology R-HSA-1266738 3.799840e-02 1.420 0 0
Chromosome Maintenance R-HSA-73886 3.834058e-02 1.416 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 3.846412e-02 1.415 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 3.898089e-02 1.409 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.898089e-02 1.409 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 5.652355e-02 1.248 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 5.652355e-02 1.248 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 5.652355e-02 1.248 0 0
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) R-HSA-1299308 5.652355e-02 1.248 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 5.652355e-02 1.248 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.208664e-02 1.376 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 4.208664e-02 1.376 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.645330e-02 1.333 0 0
Signaling by APC mutants R-HSA-4839744 4.645330e-02 1.333 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 4.645330e-02 1.333 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 4.645330e-02 1.333 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 4.645330e-02 1.333 0 0
Translesion synthesis by POLI R-HSA-5656121 4.440149e-02 1.353 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 4.440149e-02 1.353 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.258008e-02 1.279 0 0
Disorders of Developmental Biology R-HSA-9675151 5.258008e-02 1.279 0 0
Translesion synthesis by POLK R-HSA-5655862 5.258008e-02 1.279 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 4.043837e-02 1.393 0 0
RET signaling R-HSA-8853659 5.682471e-02 1.245 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 5.343762e-02 1.272 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.640537e-02 1.333 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 5.064806e-02 1.295 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 5.398416e-02 1.268 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 3.978532e-02 1.400 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 4.649754e-02 1.333 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 5.398416e-02 1.268 0 0
MTOR signalling R-HSA-165159 5.343762e-02 1.272 0 0
TNF signaling R-HSA-75893 4.640537e-02 1.333 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 4.684073e-02 1.329 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 5.095955e-02 1.293 0 0
Prolonged ERK activation events R-HSA-169893 4.440149e-02 1.353 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 4.466681e-02 1.350 0 0
NOD1/2 Signaling Pathway R-HSA-168638 4.549990e-02 1.342 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 4.549990e-02 1.342 0 0
mTORC1-mediated signalling R-HSA-166208 5.398416e-02 1.268 0 0
MyD88-independent TLR4 cascade R-HSA-166166 4.893501e-02 1.310 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 4.893501e-02 1.310 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.208664e-02 1.376 0 0
Degradation of CDH1 R-HSA-9766229 4.990991e-02 1.302 0 0
NGF-stimulated transcription R-HSA-9031628 4.535193e-02 1.343 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.235887e-02 1.373 0 0
Mitophagy R-HSA-5205647 4.549990e-02 1.342 0 0
HIV Life Cycle R-HSA-162587 5.239511e-02 1.281 0 0
HIV Infection R-HSA-162906 5.404618e-02 1.267 0 0
Gene expression (Transcription) R-HSA-74160 3.928067e-02 1.406 0 0
Signaling by AMER1 mutants R-HSA-4839748 5.695599e-02 1.244 0 0
Signaling by AXIN mutants R-HSA-4839735 5.695599e-02 1.244 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 3.978532e-02 1.400 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 4.682372e-02 1.330 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 4.440149e-02 1.353 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 4.640537e-02 1.333 0 0
Telomere Maintenance R-HSA-157579 5.885194e-02 1.230 0 0
Signaling by FGFR1 R-HSA-5654736 4.640537e-02 1.333 0 0
Signaling by PDGFR in disease R-HSA-9671555 4.686352e-02 1.329 0 0
Organelle biogenesis and maintenance R-HSA-1852241 5.721045e-02 1.243 0 0
Signaling by KIT in disease R-HSA-9669938 5.398416e-02 1.268 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 5.387961e-02 1.269 0 0
Glucose metabolism R-HSA-70326 5.046534e-02 1.297 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 4.110775e-02 1.386 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.110775e-02 1.386 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 5.070763e-02 1.295 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 5.258008e-02 1.279 0 0
NF-kB is activated and signals survival R-HSA-209560 5.695599e-02 1.244 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 5.876721e-02 1.231 0 0
SARS-CoV Infections R-HSA-9679506 4.473927e-02 1.349 0 0
XBP1(S) activates chaperone genes R-HSA-381038 4.261715e-02 1.370 0 0
Selenoamino acid metabolism R-HSA-2408522 4.786031e-02 1.320 0 0
Centrosome maturation R-HSA-380287 5.892748e-02 1.230 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 5.892748e-02 1.230 0 0
TBC/RABGAPs R-HSA-8854214 5.894073e-02 1.230 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 5.971480e-02 1.224 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.974289e-02 1.224 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 5.977317e-02 1.223 0 0
Nucleotide Excision Repair R-HSA-5696398 6.075226e-02 1.216 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 6.075226e-02 1.216 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 6.157736e-02 1.211 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 6.157736e-02 1.211 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 6.157736e-02 1.211 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 6.158355e-02 1.211 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 6.172499e-02 1.210 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 6.172499e-02 1.210 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.203713e-02 1.207 0 0
Clathrin-mediated endocytosis R-HSA-8856828 6.290071e-02 1.201 0 0
Intracellular signaling by second messengers R-HSA-9006925 6.433763e-02 1.192 0 0
Regulated Necrosis R-HSA-5218859 6.448075e-02 1.191 0 0
IRE1alpha activates chaperones R-HSA-381070 6.461426e-02 1.190 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 6.537927e-02 1.185 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 6.698467e-02 1.174 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 6.698467e-02 1.174 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 6.698467e-02 1.174 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 6.698467e-02 1.174 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 6.862062e-02 1.164 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 6.862062e-02 1.164 0 0
Pervasive developmental disorders R-HSA-9005895 6.862062e-02 1.164 0 0
Disorders of Nervous System Development R-HSA-9697154 6.862062e-02 1.164 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 6.862062e-02 1.164 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 6.862062e-02 1.164 0 0
Regulation of IFNG signaling R-HSA-877312 6.862062e-02 1.164 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 6.862062e-02 1.164 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 6.862062e-02 1.164 0 0
Signaling by Nuclear Receptors R-HSA-9006931 6.930614e-02 1.159 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 7.008833e-02 1.154 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.008833e-02 1.154 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 7.008833e-02 1.154 0 0
MAP kinase activation R-HSA-450294 7.056781e-02 1.151 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 7.101733e-02 1.149 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.114841e-02 1.148 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 7.114841e-02 1.148 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 7.138990e-02 1.146 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 7.173863e-02 1.144 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 7.173863e-02 1.144 0 0
TRIF-mediated programmed cell death R-HSA-2562578 7.173863e-02 1.144 0 0
SOS-mediated signalling R-HSA-112412 7.173863e-02 1.144 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 7.173863e-02 1.144 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 7.173863e-02 1.144 0 0
G alpha (12/13) signalling events R-HSA-416482 7.297320e-02 1.137 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.469676e-02 1.127 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 7.530812e-02 1.123 0 0
Developmental Cell Lineages R-HSA-9734767 7.564221e-02 1.121 0 0
ER to Golgi Anterograde Transport R-HSA-199977 7.668948e-02 1.115 0 0
Stabilization of p53 R-HSA-69541 7.690184e-02 1.114 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 7.722874e-02 1.112 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 7.757007e-02 1.110 0 0
Regulation of TNFR1 signaling R-HSA-5357905 7.757007e-02 1.110 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 7.757007e-02 1.110 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 7.907242e-02 1.102 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 7.907242e-02 1.102 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 7.907242e-02 1.102 0 0
Hedgehog 'on' state R-HSA-5632684 8.024719e-02 1.096 0 0
S Phase R-HSA-69242 8.043221e-02 1.095 0 0
Frs2-mediated activation R-HSA-170968 8.141473e-02 1.089 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 8.141473e-02 1.089 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 8.200728e-02 1.086 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 8.290902e-02 1.081 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 8.290902e-02 1.081 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 8.290902e-02 1.081 0 0
FasL/ CD95L signaling R-HSA-75157 8.308236e-02 1.080 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 8.308236e-02 1.080 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 8.308236e-02 1.080 0 0
MET interacts with TNS proteins R-HSA-8875513 8.308236e-02 1.080 0 0
MET activates PTPN11 R-HSA-8865999 8.308236e-02 1.080 0 0
Signaling by VEGF R-HSA-194138 8.315926e-02 1.080 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 8.362178e-02 1.078 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.449442e-02 1.073 0 0
PIP3 activates AKT signaling R-HSA-1257604 8.712782e-02 1.060 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 8.867155e-02 1.052 0 0
Regulation by c-FLIP R-HSA-3371378 8.925308e-02 1.049 0 0
Dimerization of procaspase-8 R-HSA-69416 8.925308e-02 1.049 0 0
Formation of annular gap junctions R-HSA-196025 8.925308e-02 1.049 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 9.032811e-02 1.044 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 9.086775e-02 1.042 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 9.086775e-02 1.042 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 9.161853e-02 1.038 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 9.161853e-02 1.038 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.199982e-02 1.036 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.237283e-02 1.034 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 9.237283e-02 1.034 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 9.237283e-02 1.034 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 9.238524e-02 1.034 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 9.341252e-02 1.030 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 9.341252e-02 1.030 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 9.341252e-02 1.030 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 9.341252e-02 1.030 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 9.341252e-02 1.030 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 9.341252e-02 1.030 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 9.341252e-02 1.030 0 0
Signal transduction by L1 R-HSA-445144 9.341252e-02 1.030 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 9.341252e-02 1.030 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 9.341252e-02 1.030 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.453992e-02 1.024 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.453992e-02 1.024 0 0
RSV-host interactions R-HSA-9833110 9.453992e-02 1.024 0 0
Zinc transporters R-HSA-435354 9.529368e-02 1.021 0 0
Signaling by NOTCH4 R-HSA-9013694 9.825096e-02 1.008 0 0
Cristae formation R-HSA-8949613 9.887622e-02 1.005 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 1.008199e-01 0.996 0 0
Signal amplification R-HSA-392518 1.008199e-01 0.996 0 0
Nuclear import of Rev protein R-HSA-180746 1.008199e-01 0.996 0 0
Signaling by NOTCH2 R-HSA-1980145 1.008199e-01 0.996 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.011059e-01 0.995 0 0
Ion channel transport R-HSA-983712 1.026706e-01 0.989 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.734834e-01 0.761 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.734834e-01 0.761 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.734834e-01 0.761 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.734834e-01 0.761 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.734834e-01 0.761 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.734834e-01 0.761 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.734834e-01 0.761 0 0
Hereditary fructose intolerance R-HSA-5657560 1.734834e-01 0.761 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 1.734834e-01 0.761 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 1.734834e-01 0.761 0 0
TGFBR2 MSI Frameshift Mutants in Cancer R-HSA-3642279 1.734834e-01 0.761 0 0
TICAM1 deficiency - HSE R-HSA-5602566 1.734834e-01 0.761 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.126058e-01 0.948 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.126058e-01 0.948 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 1.126058e-01 0.948 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.126058e-01 0.948 0 0
IRS activation R-HSA-74713 1.443367e-01 0.841 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.443367e-01 0.841 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 1.443367e-01 0.841 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 1.443367e-01 0.841 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 1.083559e-01 0.965 0 0
Lipophagy R-HSA-9613354 1.083559e-01 0.965 0 0
CASP8 activity is inhibited R-HSA-5218900 1.083559e-01 0.965 0 0
ALK mutants bind TKIs R-HSA-9700645 1.083559e-01 0.965 0 0
Pentose phosphate pathway disease R-HSA-6791465 1.776306e-01 0.750 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 1.776306e-01 0.750 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.776306e-01 0.750 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 1.776306e-01 0.750 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 1.288772e-01 0.890 0 0
MAPK3 (ERK1) activation R-HSA-110056 1.288772e-01 0.890 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.288772e-01 0.890 0 0
G beta:gamma signalling through BTK R-HSA-8964315 1.102025e-01 0.958 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 1.260775e-01 0.899 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.260775e-01 0.899 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.428484e-01 0.845 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 1.428484e-01 0.845 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.320988e-01 0.879 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 1.787713e-01 0.748 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 1.210464e-01 0.917 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.329759e-01 0.876 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 1.767541e-01 0.753 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 1.767541e-01 0.753 0 0
G protein gated Potassium channels R-HSA-1296059 1.767541e-01 0.753 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 1.767541e-01 0.753 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.244415e-01 0.905 0 0
Orc1 removal from chromatin R-HSA-68949 1.244415e-01 0.905 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 2.046070e-01 0.689 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.991011e-01 0.701 0 0
MET promotes cell motility R-HSA-8875878 1.423549e-01 0.847 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 1.734701e-01 0.761 0 0
Activation of the pre-replicative complex R-HSA-68962 1.329759e-01 0.876 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.927683e-01 0.715 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.381832e-01 0.860 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 1.847290e-01 0.733 0 0
Polo-like kinase mediated events R-HSA-156711 1.787713e-01 0.748 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.944754e-01 0.711 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.857734e-01 0.731 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.102025e-01 0.958 0 0
G-protein activation R-HSA-202040 1.055826e-01 0.976 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 1.927683e-01 0.715 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.718664e-01 0.765 0 0
Ca-dependent events R-HSA-111996 1.094975e-01 0.961 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.443367e-01 0.841 0 0
PI3K/AKT activation R-HSA-198203 1.288772e-01 0.890 0 0
Regulation of Apoptosis R-HSA-169911 1.105053e-01 0.957 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.718664e-01 0.765 0 0
Regulation of mitotic cell cycle R-HSA-453276 1.394483e-01 0.856 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 1.394483e-01 0.856 0 0
CaM pathway R-HSA-111997 1.206647e-01 0.918 0 0
Calmodulin induced events R-HSA-111933 1.206647e-01 0.918 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.718664e-01 0.765 0 0
Degradation of CRY and PER proteins R-HSA-9932298 1.907593e-01 0.720 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.734701e-01 0.761 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 1.055826e-01 0.976 0 0
E2F mediated regulation of DNA replication R-HSA-113510 1.977620e-01 0.704 0 0
Trafficking of AMPA receptors R-HSA-399719 1.454394e-01 0.837 0 0
G-protein mediated events R-HSA-112040 1.840106e-01 0.735 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.816098e-01 0.741 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 1.381832e-01 0.860 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.054147e-01 0.687 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.054147e-01 0.687 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.054147e-01 0.687 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.054147e-01 0.687 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 1.288772e-01 0.890 0 0
Activation and oligomerization of BAK protein R-HSA-111452 1.734834e-01 0.761 0 0
Calcineurin activates NFAT R-HSA-2025928 1.083559e-01 0.965 0 0
Synthesis of PI R-HSA-1483226 1.506411e-01 0.822 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.734701e-01 0.761 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 1.428484e-01 0.845 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 1.718664e-01 0.765 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 1.780775e-01 0.749 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.787713e-01 0.748 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.612739e-01 0.792 0 0
Neurodegenerative Diseases R-HSA-8863678 1.612739e-01 0.792 0 0
UCH proteinases R-HSA-5689603 1.115009e-01 0.953 0 0
Signaling by WNT in cancer R-HSA-4791275 1.584120e-01 0.800 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.454394e-01 0.837 0 0
Protein-protein interactions at synapses R-HSA-6794362 1.829792e-01 0.738 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 1.977620e-01 0.704 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 1.907593e-01 0.720 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 1.907593e-01 0.720 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 1.920339e-01 0.717 0 0
Signalling to ERKs R-HSA-187687 1.105053e-01 0.957 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.463741e-01 0.835 0 0
DARPP-32 events R-HSA-180024 1.210464e-01 0.917 0 0
Circadian clock R-HSA-9909396 1.218814e-01 0.914 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.184891e-01 0.926 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.907593e-01 0.720 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 1.478206e-01 0.830 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 2.001023e-01 0.699 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 1.977620e-01 0.704 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 1.971890e-01 0.705 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 1.313359e-01 0.882 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.734834e-01 0.761 0 0
Inhibition of PKR R-HSA-169131 1.734834e-01 0.761 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.126058e-01 0.948 0 0
Reelin signalling pathway R-HSA-8866376 1.443367e-01 0.841 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 1.083559e-01 0.965 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.083559e-01 0.965 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 1.776306e-01 0.750 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.260775e-01 0.899 0 0
Signaling by LTK R-HSA-9842663 1.971890e-01 0.705 0 0
Presynaptic function of Kainate receptors R-HSA-500657 1.787713e-01 0.748 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.312860e-01 0.882 0 0
RMTs methylate histone arginines R-HSA-3214858 1.282323e-01 0.892 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 1.657693e-01 0.780 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 2.001023e-01 0.699 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 1.591979e-01 0.798 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.370587e-01 0.863 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 2.037925e-01 0.691 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.054147e-01 0.687 0 0
Generic Transcription Pathway R-HSA-212436 1.049372e-01 0.979 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.409430e-01 0.851 0 0
Potential therapeutics for SARS R-HSA-9679191 1.308805e-01 0.883 0 0
Signaling by Hedgehog R-HSA-5358351 1.633153e-01 0.787 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.816098e-01 0.741 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.816098e-01 0.741 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 1.584120e-01 0.800 0 0
Vpu mediated degradation of CD4 R-HSA-180534 1.857734e-01 0.731 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.485090e-01 0.828 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 2.001023e-01 0.699 0 0
Hedgehog ligand biogenesis R-HSA-5358346 2.052990e-01 0.688 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.054147e-01 0.687 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 1.419247e-01 0.848 0 0
Calnexin/calreticulin cycle R-HSA-901042 2.001023e-01 0.699 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 1.927683e-01 0.715 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 1.083559e-01 0.965 0 0
TGFBR3 expression R-HSA-9839394 1.767541e-01 0.753 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 1.184891e-01 0.926 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 1.381832e-01 0.860 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 1.381832e-01 0.860 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.288772e-01 0.890 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.313359e-01 0.882 0 0
Signaling by TGFBR3 R-HSA-9839373 1.485090e-01 0.828 0 0
Hedgehog 'off' state R-HSA-5610787 1.801672e-01 0.744 0 0
Interleukin-17 signaling R-HSA-448424 1.313359e-01 0.882 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 1.776306e-01 0.750 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.718664e-01 0.765 0 0
snRNP Assembly R-HSA-191859 1.942742e-01 0.712 0 0
Metabolism of non-coding RNA R-HSA-194441 1.942742e-01 0.712 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 1.329759e-01 0.876 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.478206e-01 0.830 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 1.055826e-01 0.976 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.767541e-01 0.753 0 0
Gluconeogenesis R-HSA-70263 1.702363e-01 0.769 0 0
Interleukin-1 family signaling R-HSA-446652 2.005110e-01 0.698 0 0
CASP4 inflammasome assembly R-HSA-9948001 1.288772e-01 0.890 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 1.055826e-01 0.976 0 0
Growth hormone receptor signaling R-HSA-982772 1.463741e-01 0.835 0 0
Metal ion SLC transporters R-HSA-425410 1.702363e-01 0.769 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.047517e-01 0.980 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 1.857734e-01 0.731 0 0
Co-inhibition by BTLA R-HSA-9927353 1.443367e-01 0.841 0 0
Plasma lipoprotein clearance R-HSA-8964043 1.538552e-01 0.813 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.657693e-01 0.780 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.780775e-01 0.749 0 0
Pyruvate metabolism R-HSA-70268 1.343894e-01 0.872 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 1.744400e-01 0.758 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.394483e-01 0.856 0 0
Signaling by Leptin R-HSA-2586552 1.288772e-01 0.890 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.776306e-01 0.750 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.428484e-01 0.845 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.787713e-01 0.748 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.282323e-01 0.892 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 2.001023e-01 0.699 0 0
Regulation of BACH1 activity R-HSA-9708530 1.260775e-01 0.899 0 0
Glycogen storage diseases R-HSA-3229121 1.604395e-01 0.795 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.080584e-01 0.682 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.092680e-01 0.679 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 2.092680e-01 0.679 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 2.092680e-01 0.679 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 2.092680e-01 0.679 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.119419e-01 0.674 0 0
CREB phosphorylation R-HSA-199920 2.119419e-01 0.674 0 0
Signaling by LTK in cancer R-HSA-9842640 2.119419e-01 0.674 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 2.119419e-01 0.674 0 0
STAT5 Activation R-HSA-9645135 2.119419e-01 0.674 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.119419e-01 0.674 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 2.119419e-01 0.674 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 2.119419e-01 0.674 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.119419e-01 0.674 0 0
Abacavir transmembrane transport R-HSA-2161517 2.119419e-01 0.674 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 2.119419e-01 0.674 0 0
Cellular response to chemical stress R-HSA-9711123 2.131700e-01 0.671 0 0
PERK regulates gene expression R-HSA-381042 2.148208e-01 0.668 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 2.148208e-01 0.668 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 2.148208e-01 0.668 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 2.148208e-01 0.668 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 2.152908e-01 0.667 0 0
Integration of energy metabolism R-HSA-163685 2.152908e-01 0.667 0 0
Infectious disease R-HSA-5663205 2.165485e-01 0.664 0 0
PLC beta mediated events R-HSA-112043 2.168093e-01 0.664 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 2.171541e-01 0.663 0 0
Response of Mtb to phagocytosis R-HSA-9637690 2.171541e-01 0.663 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.173284e-01 0.663 0 0
Protein hydroxylation R-HSA-9629569 2.173284e-01 0.663 0 0
Formation of definitive endoderm R-HSA-9823730 2.173284e-01 0.663 0 0
Neurexins and neuroligins R-HSA-6794361 2.175807e-01 0.662 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.216276e-01 0.654 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 2.216276e-01 0.654 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 2.216276e-01 0.654 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 2.216276e-01 0.654 0 0
Interleukin-6 signaling R-HSA-1059683 2.216276e-01 0.654 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 2.216276e-01 0.654 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 2.262036e-01 0.646 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 2.272796e-01 0.643 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.298955e-01 0.638 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 2.308200e-01 0.637 0 0
Netrin-1 signaling R-HSA-373752 2.308200e-01 0.637 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 2.373874e-01 0.625 0 0
Basigin interactions R-HSA-210991 2.373874e-01 0.625 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 2.373874e-01 0.625 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.373874e-01 0.625 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 2.401662e-01 0.619 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 2.403033e-01 0.619 0 0
Platelet homeostasis R-HSA-418346 2.408603e-01 0.618 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.414315e-01 0.617 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 2.429280e-01 0.615 0 0
Signaling by Erythropoietin R-HSA-9006335 2.435247e-01 0.613 0 0
Cardiac conduction R-HSA-5576891 2.435885e-01 0.613 0 0
DAG and IP3 signaling R-HSA-1489509 2.447655e-01 0.611 0 0
Fanconi Anemia Pathway R-HSA-6783310 2.447655e-01 0.611 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 2.447655e-01 0.611 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.447655e-01 0.611 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.447655e-01 0.611 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 2.447655e-01 0.611 0 0
Degradation of DVL R-HSA-4641258 2.452923e-01 0.610 0 0
Degradation of AXIN R-HSA-4641257 2.452923e-01 0.610 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 2.452923e-01 0.610 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 2.466230e-01 0.608 0 0
CRMPs in Sema3A signaling R-HSA-399956 2.466230e-01 0.608 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 2.466230e-01 0.608 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 2.466230e-01 0.608 0 0
Signaling by FGFR4 in disease R-HSA-5655291 2.466230e-01 0.608 0 0
Signal regulatory protein family interactions R-HSA-391160 2.466230e-01 0.608 0 0
Non-canonical inflammasome activation R-HSA-9686114 2.466230e-01 0.608 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 2.468113e-01 0.608 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 2.468113e-01 0.608 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 2.468113e-01 0.608 0 0
IFNG signaling activates MAPKs R-HSA-9732724 2.468113e-01 0.608 0 0
Recycling of eIF2:GDP R-HSA-72731 2.468113e-01 0.608 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 2.468113e-01 0.608 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 2.468113e-01 0.608 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 2.468113e-01 0.608 0 0
Netrin mediated repulsion signals R-HSA-418886 2.468113e-01 0.608 0 0
CHL1 interactions R-HSA-447041 2.468113e-01 0.608 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 2.468113e-01 0.608 0 0
IKBKB deficiency causes SCID R-HSA-5602636 2.485960e-01 0.605 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.485960e-01 0.605 0 0
TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P R-HSA-6791055 2.485960e-01 0.605 0 0
MyD88 deficiency (TLR5) R-HSA-5602680 2.485960e-01 0.605 0 0
TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P R-HSA-6791462 2.485960e-01 0.605 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.485960e-01 0.605 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 2.485960e-01 0.605 0 0
Defective HK1 causes hexokinase deficiency (HK deficiency) R-HSA-5619056 2.485960e-01 0.605 0 0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 2.485960e-01 0.605 0 0
Defective GFPT1 causes CMSTA1 R-HSA-4085023 2.485960e-01 0.605 0 0
TRAF3 deficiency - HSE R-HSA-5602571 2.485960e-01 0.605 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 2.485960e-01 0.605 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.485960e-01 0.605 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.485960e-01 0.605 0 0
NTRK3 as a dependence receptor R-HSA-9603505 2.485960e-01 0.605 0 0
Synthesis of DNA R-HSA-69239 2.501352e-01 0.602 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 2.523730e-01 0.598 0 0
Mitochondrial calcium ion transport R-HSA-8949215 2.578565e-01 0.589 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 2.578565e-01 0.589 0 0
Disease R-HSA-1643685 2.586204e-01 0.587 0 0
Diseases of DNA repair R-HSA-9675135 2.589653e-01 0.587 0 0
Regulation of pyruvate metabolism R-HSA-9861718 2.589653e-01 0.587 0 0
Stimuli-sensing channels R-HSA-2672351 2.595421e-01 0.586 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 2.609764e-01 0.583 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.611804e-01 0.583 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 2.611804e-01 0.583 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 2.611804e-01 0.583 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.662363e-01 0.575 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.662363e-01 0.575 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.662363e-01 0.575 0 0
NRAGE signals death through JNK R-HSA-193648 2.691929e-01 0.570 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.691929e-01 0.570 0 0
Erythropoietin activates RAS R-HSA-9027284 2.720209e-01 0.565 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 2.720209e-01 0.565 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 2.720209e-01 0.565 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 2.720209e-01 0.565 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.720209e-01 0.565 0 0
DNA Damage Reversal R-HSA-73942 2.720209e-01 0.565 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 2.733936e-01 0.563 0 0
RAS processing R-HSA-9648002 2.769130e-01 0.558 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 2.769130e-01 0.558 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 2.769130e-01 0.558 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.786549e-01 0.555 0 0
TCR signaling R-HSA-202403 2.787250e-01 0.555 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 2.818543e-01 0.550 0 0
ALKBH3 mediated reversal of alkylation damage R-HSA-112126 2.818543e-01 0.550 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 2.818543e-01 0.550 0 0
MET receptor recycling R-HSA-8875656 2.818543e-01 0.550 0 0
Adrenoceptors R-HSA-390696 2.818543e-01 0.550 0 0
Intraflagellar transport R-HSA-5620924 2.880246e-01 0.541 0 0
GPER1 signaling R-HSA-9634597 2.880246e-01 0.541 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.895804e-01 0.538 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 2.910874e-01 0.536 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 2.930668e-01 0.533 0 0
G0 and Early G1 R-HSA-1538133 2.972938e-01 0.527 0 0
Inwardly rectifying K+ channels R-HSA-1296065 2.972938e-01 0.527 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 2.976772e-01 0.526 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 2.976772e-01 0.526 0 0
Phosphorylation of the APC/C R-HSA-176412 2.976772e-01 0.526 0 0
Activation of SMO R-HSA-5635838 2.976772e-01 0.526 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.997039e-01 0.523 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 2.997039e-01 0.523 0 0
Syndecan interactions R-HSA-3000170 2.997039e-01 0.523 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.024361e-01 0.519 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 3.028320e-01 0.519 0 0
PCP/CE pathway R-HSA-4086400 3.072560e-01 0.512 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.094029e-01 0.509 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 3.094029e-01 0.509 0 0
G-protein beta:gamma signalling R-HSA-397795 3.156517e-01 0.501 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.156517e-01 0.501 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 3.167517e-01 0.499 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 3.167517e-01 0.499 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.167517e-01 0.499 0 0
MAPK1 (ERK2) activation R-HSA-112411 3.167517e-01 0.499 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.167517e-01 0.499 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.167517e-01 0.499 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 3.167517e-01 0.499 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 3.168866e-01 0.499 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 3.168866e-01 0.499 0 0
Signaling by RAS GAP mutants R-HSA-9753510 3.168866e-01 0.499 0 0
mRNA Editing: A to I Conversion R-HSA-75064 3.168866e-01 0.499 0 0
C6 deamination of adenosine R-HSA-75102 3.168866e-01 0.499 0 0
Signalling to ERK5 R-HSA-198765 3.168866e-01 0.499 0 0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis R-HSA-9708296 3.168866e-01 0.499 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 3.209281e-01 0.494 0 0
Thromboxane signalling through TP receptor R-HSA-428930 3.209281e-01 0.494 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 3.209281e-01 0.494 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 3.233170e-01 0.490 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 3.234581e-01 0.490 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 3.234581e-01 0.490 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 3.234581e-01 0.490 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.234581e-01 0.490 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.250617e-01 0.488 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 3.258866e-01 0.487 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 3.328719e-01 0.478 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 3.341459e-01 0.476 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 3.378196e-01 0.471 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.422549e-01 0.466 0 0
Interleukin-7 signaling R-HSA-1266695 3.422549e-01 0.466 0 0
Activation of GABAB receptors R-HSA-991365 3.424840e-01 0.465 0 0
GABA B receptor activation R-HSA-977444 3.424840e-01 0.465 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 3.424840e-01 0.465 0 0
Downstream TCR signaling R-HSA-202424 3.459388e-01 0.461 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 3.473277e-01 0.459 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 3.473277e-01 0.459 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 3.473277e-01 0.459 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 3.480528e-01 0.458 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 3.480528e-01 0.458 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 3.480528e-01 0.458 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 3.492409e-01 0.457 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 3.492409e-01 0.457 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 3.492409e-01 0.457 0 0
Binding and entry of HIV virion R-HSA-173107 3.512407e-01 0.454 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.512407e-01 0.454 0 0
Regulation of CDH11 function R-HSA-9762292 3.512407e-01 0.454 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 3.512407e-01 0.454 0 0
Signal attenuation R-HSA-74749 3.512407e-01 0.454 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 3.512407e-01 0.454 0 0
Tandem pore domain potassium channels R-HSA-1296346 3.512407e-01 0.454 0 0
Toll-like Receptor Cascades R-HSA-168898 3.561670e-01 0.448 0 0
FOXO-mediated transcription R-HSA-9614085 3.585625e-01 0.445 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 3.624979e-01 0.441 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 3.633070e-01 0.440 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.636157e-01 0.439 0 0
Myogenesis R-HSA-525793 3.636157e-01 0.439 0 0
TRP channels R-HSA-3295583 3.636157e-01 0.439 0 0
Suppression of phagosomal maturation R-HSA-9637687 3.636157e-01 0.439 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.660294e-01 0.436 0 0
Rab regulation of trafficking R-HSA-9007101 3.696786e-01 0.432 0 0
Mismatch Repair R-HSA-5358508 3.749140e-01 0.426 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 3.749140e-01 0.426 0 0
Tie2 Signaling R-HSA-210993 3.749140e-01 0.426 0 0
Axonal growth stimulation R-HSA-209563 3.789742e-01 0.421 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 3.789742e-01 0.421 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 3.789742e-01 0.421 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.789742e-01 0.421 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.789742e-01 0.421 0 0
STAT6-mediated induction of chemokines R-HSA-3249367 3.789742e-01 0.421 0 0
Intracellular oxygen transport R-HSA-8981607 3.789742e-01 0.421 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 3.789742e-01 0.421 0 0
Histamine receptors R-HSA-390650 3.789742e-01 0.421 0 0
Insulin processing R-HSA-264876 3.849458e-01 0.415 0 0
Formation of the posterior neural plate R-HSA-9832991 3.851074e-01 0.414 0 0
vRNP Assembly R-HSA-192905 3.851074e-01 0.414 0 0
GPVI-mediated activation cascade R-HSA-114604 3.899860e-01 0.409 0 0
Triglyceride catabolism R-HSA-163560 3.899860e-01 0.409 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 3.926282e-01 0.406 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 3.926282e-01 0.406 0 0
G alpha (z) signalling events R-HSA-418597 3.939369e-01 0.405 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 3.940122e-01 0.404 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 4.003769e-01 0.398 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 4.003769e-01 0.398 0 0
STING mediated induction of host immune responses R-HSA-1834941 4.003769e-01 0.398 0 0
Other interleukin signaling R-HSA-449836 4.003769e-01 0.398 0 0
Maturation of nucleoprotein R-HSA-9694631 4.003769e-01 0.398 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 4.061848e-01 0.391 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.061848e-01 0.391 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 4.061848e-01 0.391 0 0
Signaling by NOTCH1 R-HSA-1980143 4.077305e-01 0.390 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 4.092646e-01 0.388 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.181802e-01 0.379 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 4.181802e-01 0.379 0 0
Integration of provirus R-HSA-162592 4.181802e-01 0.379 0 0
Sodium/Calcium exchangers R-HSA-425561 4.181802e-01 0.379 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 4.191807e-01 0.378 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 4.210603e-01 0.376 0 0
IRS-mediated signalling R-HSA-112399 4.245701e-01 0.372 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 4.255396e-01 0.371 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 4.255396e-01 0.371 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 4.260387e-01 0.371 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 4.272763e-01 0.369 0 0
Platelet calcium homeostasis R-HSA-418360 4.272763e-01 0.369 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.272763e-01 0.369 0 0
Glucagon-type ligand receptors R-HSA-420092 4.272763e-01 0.369 0 0
Transmission across Chemical Synapses R-HSA-112315 4.311183e-01 0.365 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 4.343756e-01 0.362 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 4.354222e-01 0.361 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 4.354222e-01 0.361 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 4.354222e-01 0.361 0 0
Signaling by MAP2K mutants R-HSA-9652169 4.354222e-01 0.361 0 0
Defective FMO3 causes TMAU R-HSA-5579019 4.354222e-01 0.361 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 4.354222e-01 0.361 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 4.354222e-01 0.361 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 4.354222e-01 0.361 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.354222e-01 0.361 0 0
NADE modulates death signalling R-HSA-205025 4.354222e-01 0.361 0 0
Dopamine receptors R-HSA-390651 4.354222e-01 0.361 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 4.354222e-01 0.361 0 0
Neuronal System R-HSA-112316 4.367223e-01 0.360 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 4.454748e-01 0.351 0 0
Signaling by ALK R-HSA-201556 4.454748e-01 0.351 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 4.462418e-01 0.350 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 4.462418e-01 0.350 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 4.469268e-01 0.350 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 4.471433e-01 0.350 0 0
Sensory processing of sound R-HSA-9659379 4.476619e-01 0.349 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 4.481686e-01 0.349 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 4.481686e-01 0.349 0 0
Early Phase of HIV Life Cycle R-HSA-162594 4.503228e-01 0.346 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 4.503238e-01 0.346 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 4.503238e-01 0.346 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.503238e-01 0.346 0 0
Repression of WNT target genes R-HSA-4641265 4.503238e-01 0.346 0 0
Interleukin-15 signaling R-HSA-8983432 4.503238e-01 0.346 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 4.503238e-01 0.346 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.503238e-01 0.346 0 0
GRB2 events in EGFR signaling R-HSA-179812 4.503238e-01 0.346 0 0
MET activates RAS signaling R-HSA-8851805 4.503238e-01 0.346 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 4.503238e-01 0.346 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.503238e-01 0.346 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 4.503238e-01 0.346 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 4.503238e-01 0.346 0 0
ER-Phagosome pathway R-HSA-1236974 4.568593e-01 0.340 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 4.603466e-01 0.337 0 0
Downstream signal transduction R-HSA-186763 4.688142e-01 0.329 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 4.722829e-01 0.326 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 4.740056e-01 0.324 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 4.746570e-01 0.324 0 0
PI3K Cascade R-HSA-109704 4.755544e-01 0.323 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 4.814339e-01 0.317 0 0
CD28 dependent Vav1 pathway R-HSA-389359 4.814339e-01 0.317 0 0
Formation of axial mesoderm R-HSA-9796292 4.814339e-01 0.317 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 4.814339e-01 0.317 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 4.817727e-01 0.317 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 4.817727e-01 0.317 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 4.835833e-01 0.316 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 4.851411e-01 0.314 0 0
Viral Messenger RNA Synthesis R-HSA-168325 4.851411e-01 0.314 0 0
Aquaporin-mediated transport R-HSA-445717 4.851411e-01 0.314 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 4.867423e-01 0.313 0 0
NTRK2 activates RAC1 R-HSA-9032759 4.867423e-01 0.313 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 4.867423e-01 0.313 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.867423e-01 0.313 0 0
PTK6 Down-Regulation R-HSA-8849472 4.867423e-01 0.313 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 4.867423e-01 0.313 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 4.867423e-01 0.313 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.867423e-01 0.313 0 0
Inositol transporters R-HSA-429593 4.867423e-01 0.313 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 4.867423e-01 0.313 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 4.867423e-01 0.313 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 4.867423e-01 0.313 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 4.867423e-01 0.313 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 4.867423e-01 0.313 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 4.917975e-01 0.308 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 4.932252e-01 0.307 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 4.984821e-01 0.302 0 0
Notch-HLH transcription pathway R-HSA-350054 4.984821e-01 0.302 0 0
Fructose metabolism R-HSA-5652084 4.984821e-01 0.302 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 4.984821e-01 0.302 0 0
LDL clearance R-HSA-8964038 4.984821e-01 0.302 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 4.984821e-01 0.302 0 0
Translation of Structural Proteins R-HSA-9683701 4.996164e-01 0.301 0 0
NCAM signaling for neurite out-growth R-HSA-375165 5.000219e-01 0.301 0 0
Interleukin-1 signaling R-HSA-9020702 5.003832e-01 0.301 0 0
Ca2+ pathway R-HSA-4086398 5.070345e-01 0.295 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 5.091969e-01 0.293 0 0
Nuclear RNA decay R-HSA-9930044 5.091969e-01 0.293 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.091969e-01 0.293 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 5.091969e-01 0.293 0 0
Cardiogenesis R-HSA-9733709 5.091969e-01 0.293 0 0
Removal of the Flap Intermediate R-HSA-69166 5.114328e-01 0.291 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 5.114328e-01 0.291 0 0
Hydrolysis of LPC R-HSA-1483115 5.114328e-01 0.291 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 5.114328e-01 0.291 0 0
Physiological factors R-HSA-5578768 5.114328e-01 0.291 0 0
Inositol phosphate metabolism R-HSA-1483249 5.171595e-01 0.286 0 0
PTEN Regulation R-HSA-6807070 5.204604e-01 0.284 0 0
Signaling by FGFR in disease R-HSA-1226099 5.207226e-01 0.283 0 0
Interleukin-20 family signaling R-HSA-8854691 5.217472e-01 0.283 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 5.237545e-01 0.281 0 0
Regulation of PTEN stability and activity R-HSA-8948751 5.237545e-01 0.281 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 5.282168e-01 0.277 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 5.288606e-01 0.277 0 0
IGF1R signaling cascade R-HSA-2428924 5.293442e-01 0.276 0 0
Insulin receptor signalling cascade R-HSA-74751 5.293442e-01 0.276 0 0
Plus-strand DNA synthesis R-HSA-164525 5.334002e-01 0.273 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 5.334002e-01 0.273 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 5.334002e-01 0.273 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 5.334002e-01 0.273 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 5.334002e-01 0.273 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 5.334002e-01 0.273 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 5.334002e-01 0.273 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 5.334002e-01 0.273 0 0
TRAIL signaling R-HSA-75158 5.334002e-01 0.273 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 5.334002e-01 0.273 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 5.334002e-01 0.273 0 0
Cam-PDE 1 activation R-HSA-111957 5.334002e-01 0.273 0 0
Intestinal hexose absorption R-HSA-8981373 5.334002e-01 0.273 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.334002e-01 0.273 0 0
Signaling by MST1 R-HSA-8852405 5.334002e-01 0.273 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 5.334002e-01 0.273 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 5.334002e-01 0.273 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 5.334002e-01 0.273 0 0
Iron uptake and transport R-HSA-917937 5.342760e-01 0.272 0 0
SHC1 events in EGFR signaling R-HSA-180336 5.402656e-01 0.267 0 0
Processive synthesis on the lagging strand R-HSA-69183 5.402656e-01 0.267 0 0
p38MAPK events R-HSA-171007 5.402656e-01 0.267 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 5.402656e-01 0.267 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 5.402656e-01 0.267 0 0
Biotin transport and metabolism R-HSA-196780 5.402656e-01 0.267 0 0
Formation of the anterior neural plate R-HSA-9823739 5.402656e-01 0.267 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 5.437539e-01 0.265 0 0
Cellular response to hypoxia R-HSA-1234174 5.437539e-01 0.265 0 0
Deadenylation of mRNA R-HSA-429947 5.444091e-01 0.264 0 0
Interleukin-6 family signaling R-HSA-6783589 5.444091e-01 0.264 0 0
Mitochondrial RNA degradation R-HSA-9836573 5.444091e-01 0.264 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 5.481303e-01 0.261 0 0
Amine ligand-binding receptors R-HSA-375280 5.516027e-01 0.258 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 5.664329e-01 0.247 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 5.664329e-01 0.247 0 0
HDMs demethylate histones R-HSA-3214842 5.664329e-01 0.247 0 0
Formation of the nephric duct R-HSA-9830364 5.664329e-01 0.247 0 0
Potassium Channels R-HSA-1296071 5.664602e-01 0.247 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 5.669793e-01 0.246 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 5.669793e-01 0.246 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 5.669793e-01 0.246 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 5.678963e-01 0.246 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 5.678963e-01 0.246 0 0
Attachment and Entry R-HSA-9678110 5.678963e-01 0.246 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 5.678963e-01 0.246 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.678963e-01 0.246 0 0
Fructose catabolism R-HSA-70350 5.678963e-01 0.246 0 0
Mineralocorticoid biosynthesis R-HSA-193993 5.678963e-01 0.246 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.678963e-01 0.246 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 5.758192e-01 0.240 0 0
Uncoating of the HIV Virion R-HSA-162585 5.758192e-01 0.240 0 0
Hydrolysis of LPE R-HSA-1483152 5.758192e-01 0.240 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 5.758192e-01 0.240 0 0
VLDL assembly R-HSA-8866423 5.758192e-01 0.240 0 0
MET Receptor Activation R-HSA-6806942 5.758192e-01 0.240 0 0
Neurofascin interactions R-HSA-447043 5.758192e-01 0.240 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 5.853846e-01 0.233 0 0
RNA Polymerase III Transcription R-HSA-74158 5.853846e-01 0.233 0 0
RUNX2 regulates bone development R-HSA-8941326 5.853846e-01 0.233 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 5.877902e-01 0.231 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 5.877902e-01 0.231 0 0
Antigen processing-Cross presentation R-HSA-1236975 5.911003e-01 0.228 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 5.943053e-01 0.226 0 0
Heme assimilation R-HSA-9927020 5.943053e-01 0.226 0 0
tRNA modification in the mitochondrion R-HSA-6787450 5.943053e-01 0.226 0 0
Galactose catabolism R-HSA-70370 5.943053e-01 0.226 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 6.033266e-01 0.219 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 6.084594e-01 0.216 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 6.084594e-01 0.216 0 0
Signaling by FGFR3 in disease R-HSA-5655332 6.084594e-01 0.216 0 0
Maturation of hRSV A proteins R-HSA-9828806 6.084594e-01 0.216 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 6.140854e-01 0.212 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 6.143841e-01 0.212 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 6.143841e-01 0.212 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 6.143841e-01 0.212 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 6.143841e-01 0.212 0 0
LDL remodeling R-HSA-8964041 6.143841e-01 0.212 0 0
VLDL clearance R-HSA-8964046 6.143841e-01 0.212 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 6.143841e-01 0.212 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 6.143841e-01 0.212 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.143841e-01 0.212 0 0
Interferon gamma signaling R-HSA-877300 6.168272e-01 0.210 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 6.194862e-01 0.208 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 6.194862e-01 0.208 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 6.194862e-01 0.208 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 6.194862e-01 0.208 0 0
Specification of primordial germ cells R-HSA-9827857 6.194862e-01 0.208 0 0
Uptake and function of anthrax toxins R-HSA-5210891 6.194862e-01 0.208 0 0
tRNA processing R-HSA-72306 6.263916e-01 0.203 0 0
GABA receptor activation R-HSA-977443 6.281807e-01 0.202 0 0
HIV elongation arrest and recovery R-HSA-167287 6.284246e-01 0.202 0 0
Pausing and recovery of HIV elongation R-HSA-167290 6.284246e-01 0.202 0 0
Leishmania phagocytosis R-HSA-9664417 6.334947e-01 0.198 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.334947e-01 0.198 0 0
Parasite infection R-HSA-9664407 6.334947e-01 0.198 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 6.350441e-01 0.197 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 6.377594e-01 0.195 0 0
Adipogenesis R-HSA-9843745 6.427882e-01 0.192 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.434441e-01 0.191 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 6.434441e-01 0.191 0 0
Apoptotic factor-mediated response R-HSA-111471 6.434441e-01 0.191 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 6.434441e-01 0.191 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.434441e-01 0.191 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 6.462935e-01 0.190 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 6.476755e-01 0.189 0 0
Reverse Transcription of HIV RNA R-HSA-162589 6.494449e-01 0.187 0 0
Minus-strand DNA synthesis R-HSA-164516 6.494449e-01 0.187 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 6.494449e-01 0.187 0 0
phospho-PLA2 pathway R-HSA-111995 6.494449e-01 0.187 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 6.494449e-01 0.187 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 6.494449e-01 0.187 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 6.494449e-01 0.187 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 6.494449e-01 0.187 0 0
Interleukin-9 signaling R-HSA-8985947 6.494449e-01 0.187 0 0
Sodium/Proton exchangers R-HSA-425986 6.494449e-01 0.187 0 0
Activation of RAS in B cells R-HSA-1169092 6.494449e-01 0.187 0 0
Co-stimulation by ICOS R-HSA-9927354 6.494449e-01 0.187 0 0
Fructose biosynthesis R-HSA-5652227 6.494449e-01 0.187 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 6.494449e-01 0.187 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.494449e-01 0.187 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.494449e-01 0.187 0 0
Intestinal absorption R-HSA-8963676 6.494449e-01 0.187 0 0
Interleukin-23 signaling R-HSA-9020933 6.494449e-01 0.187 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 6.513160e-01 0.186 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 6.542271e-01 0.184 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 6.542271e-01 0.184 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 6.542271e-01 0.184 0 0
Interleukin-2 family signaling R-HSA-451927 6.542271e-01 0.184 0 0
Mitochondrial protein import R-HSA-1268020 6.554534e-01 0.183 0 0
Heme signaling R-HSA-9707616 6.554534e-01 0.183 0 0
Protein localization R-HSA-9609507 6.600180e-01 0.180 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 6.636515e-01 0.178 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 6.661932e-01 0.176 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 6.661932e-01 0.176 0 0
DAP12 signaling R-HSA-2424491 6.662062e-01 0.176 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 6.701849e-01 0.174 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 6.755602e-01 0.170 0 0
Interleukin-21 signaling R-HSA-9020958 6.813198e-01 0.167 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 6.813198e-01 0.167 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 6.813198e-01 0.167 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 6.813198e-01 0.167 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.813198e-01 0.167 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 6.813198e-01 0.167 0 0
mRNA Editing R-HSA-75072 6.813198e-01 0.167 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.813198e-01 0.167 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 6.813198e-01 0.167 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 6.813198e-01 0.167 0 0
Regulated proteolysis of p75NTR R-HSA-193692 6.813198e-01 0.167 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 6.813198e-01 0.167 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 6.813198e-01 0.167 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 6.813198e-01 0.167 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 6.856279e-01 0.164 0 0
Scavenging by Class A Receptors R-HSA-3000480 6.856279e-01 0.164 0 0
Acyl chain remodelling of PI R-HSA-1482922 6.877551e-01 0.163 0 0
Pregnenolone biosynthesis R-HSA-196108 6.877551e-01 0.163 0 0
Metabolism of proteins R-HSA-392499 6.886483e-01 0.162 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 6.892794e-01 0.162 0 0
Nucleotide biosynthesis R-HSA-8956320 6.893335e-01 0.162 0 0
Translation of Structural Proteins R-HSA-9694635 6.990200e-01 0.156 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 7.005537e-01 0.155 0 0
Mitochondrial biogenesis R-HSA-1592230 7.019133e-01 0.154 0 0
Lagging Strand Synthesis R-HSA-69186 7.081578e-01 0.150 0 0
Signalling to RAS R-HSA-167044 7.081578e-01 0.150 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 7.081578e-01 0.150 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 7.081578e-01 0.150 0 0
ABC transporter disorders R-HSA-5619084 7.102511e-01 0.149 0 0
2-LTR circle formation R-HSA-164843 7.102981e-01 0.149 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 7.102981e-01 0.149 0 0
Regulation of the apoptosome activity R-HSA-9627069 7.102981e-01 0.149 0 0
Formation of apoptosome R-HSA-111458 7.102981e-01 0.149 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 7.102981e-01 0.149 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.102981e-01 0.149 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 7.102981e-01 0.149 0 0
Interleukin-27 signaling R-HSA-9020956 7.102981e-01 0.149 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 7.102981e-01 0.149 0 0
Receptor Mediated Mitophagy R-HSA-8934903 7.102981e-01 0.149 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.199122e-01 0.143 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.199122e-01 0.143 0 0
MITF-M-dependent gene expression R-HSA-9856651 7.270942e-01 0.138 0 0
Attachment and Entry R-HSA-9694614 7.274336e-01 0.138 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 7.274336e-01 0.138 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 7.274336e-01 0.138 0 0
Glucocorticoid biosynthesis R-HSA-194002 7.274336e-01 0.138 0 0
Serine metabolism R-HSA-977347 7.274336e-01 0.138 0 0
Androgen biosynthesis R-HSA-193048 7.274336e-01 0.138 0 0
Proteasome assembly R-HSA-9907900 7.288535e-01 0.137 0 0
ABC-family proteins mediated transport R-HSA-382556 7.288758e-01 0.137 0 0
Acyl chain remodelling of PC R-HSA-1482788 7.331520e-01 0.135 0 0
Effects of PIP2 hydrolysis R-HSA-114508 7.331520e-01 0.135 0 0
Heme degradation R-HSA-189483 7.331520e-01 0.135 0 0
Interleukin-2 signaling R-HSA-9020558 7.366430e-01 0.133 0 0
Ionotropic activity of kainate receptors R-HSA-451306 7.366430e-01 0.133 0 0
vRNA Synthesis R-HSA-192814 7.366430e-01 0.133 0 0
Chylomicron assembly R-HSA-8963888 7.366430e-01 0.133 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 7.366430e-01 0.133 0 0
Bicarbonate transporters R-HSA-425381 7.366430e-01 0.133 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 7.366430e-01 0.133 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 7.366430e-01 0.133 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 7.366430e-01 0.133 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 7.366430e-01 0.133 0 0
Suppression of apoptosis R-HSA-9635465 7.366430e-01 0.133 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.366430e-01 0.133 0 0
Dissolution of Fibrin Clot R-HSA-75205 7.366430e-01 0.133 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.455732e-01 0.128 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.455732e-01 0.128 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.456187e-01 0.127 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 7.456187e-01 0.127 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 7.456187e-01 0.127 0 0
Cellular hexose transport R-HSA-189200 7.456187e-01 0.127 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 7.456187e-01 0.127 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 7.481289e-01 0.126 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 7.521277e-01 0.124 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 7.521277e-01 0.124 0 0
Signaling by Insulin receptor R-HSA-74752 7.540138e-01 0.123 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 7.540138e-01 0.123 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 7.551032e-01 0.122 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 7.605935e-01 0.119 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 7.605935e-01 0.119 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 7.605935e-01 0.119 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 7.605935e-01 0.119 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 7.605935e-01 0.119 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 7.605935e-01 0.119 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 7.605935e-01 0.119 0 0
ERKs are inactivated R-HSA-202670 7.605935e-01 0.119 0 0
FMO oxidises nucleophiles R-HSA-217271 7.605935e-01 0.119 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 7.605935e-01 0.119 0 0
Activation of RAC1 R-HSA-428540 7.605935e-01 0.119 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 7.605935e-01 0.119 0 0
Neddylation R-HSA-8951664 7.615311e-01 0.118 0 0
Acyl chain remodelling of PE R-HSA-1482839 7.624248e-01 0.118 0 0
Formation of the ureteric bud R-HSA-9830674 7.627521e-01 0.118 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 7.627521e-01 0.118 0 0
Carnitine shuttle R-HSA-200425 7.627521e-01 0.118 0 0
Mitochondrial mRNA modification R-HSA-9937008 7.627521e-01 0.118 0 0
Triglyceride metabolism R-HSA-8979227 7.634756e-01 0.117 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 7.634756e-01 0.117 0 0
tRNA Aminoacylation R-HSA-379724 7.744261e-01 0.111 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 7.744261e-01 0.111 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 7.788747e-01 0.109 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 7.788747e-01 0.109 0 0
Complex III assembly R-HSA-9865881 7.788747e-01 0.109 0 0
Interleukin-35 Signalling R-HSA-8984722 7.823671e-01 0.107 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 7.823671e-01 0.107 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 7.823671e-01 0.107 0 0
Leading Strand Synthesis R-HSA-69109 7.823671e-01 0.107 0 0
Polymerase switching R-HSA-69091 7.823671e-01 0.107 0 0
Synthesis of GDP-mannose R-HSA-446205 7.823671e-01 0.107 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 7.823671e-01 0.107 0 0
OAS antiviral response R-HSA-8983711 7.823671e-01 0.107 0 0
Formation of paraxial mesoderm R-HSA-9793380 7.849839e-01 0.105 0 0
Voltage gated Potassium channels R-HSA-1296072 7.890357e-01 0.103 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.940284e-01 0.100 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.940284e-01 0.100 0 0
Laminin interactions R-HSA-3000157 7.940284e-01 0.100 0 0
Tight junction interactions R-HSA-420029 7.940284e-01 0.100 0 0
Signaling by PDGF R-HSA-186797 7.951543e-01 0.100 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 7.951543e-01 0.100 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 7.985318e-01 0.098 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.013850e-01 0.096 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.013850e-01 0.096 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.016483e-01 0.096 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 8.021617e-01 0.096 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 8.021617e-01 0.096 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 8.021617e-01 0.096 0 0
Processing of SMDT1 R-HSA-8949664 8.021617e-01 0.096 0 0
Maturation of nucleoprotein R-HSA-9683610 8.021617e-01 0.096 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 8.021617e-01 0.096 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.021617e-01 0.096 0 0
MET activates PTK2 signaling R-HSA-8874081 8.082562e-01 0.092 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 8.082562e-01 0.092 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 8.082562e-01 0.092 0 0
Abacavir ADME R-HSA-2161522 8.082562e-01 0.092 0 0
Sphingolipid catabolism R-HSA-9845614 8.082562e-01 0.092 0 0
Urea cycle R-HSA-70635 8.082562e-01 0.092 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 8.131216e-01 0.090 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 8.131216e-01 0.090 0 0
Pentose phosphate pathway R-HSA-71336 8.131216e-01 0.090 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.131216e-01 0.090 0 0
Post-translational protein phosphorylation R-HSA-8957275 8.132782e-01 0.090 0 0
Regulation of insulin secretion R-HSA-422356 8.132782e-01 0.090 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.199342e-01 0.086 0 0
Retrograde neurotrophin signalling R-HSA-177504 8.201569e-01 0.086 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 8.201569e-01 0.086 0 0
Prolactin receptor signaling R-HSA-1170546 8.201569e-01 0.086 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.201569e-01 0.086 0 0
Ciprofloxacin ADME R-HSA-9793528 8.201569e-01 0.086 0 0
Acyl chain remodeling of CL R-HSA-1482798 8.201569e-01 0.086 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 8.201569e-01 0.086 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.208288e-01 0.086 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 8.216010e-01 0.085 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 8.216010e-01 0.085 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 8.216010e-01 0.085 0 0
Signaling by BMP R-HSA-201451 8.216010e-01 0.085 0 0
HIV Transcription Elongation R-HSA-167169 8.242650e-01 0.084 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 8.242650e-01 0.084 0 0
Diseases of Immune System R-HSA-5260271 8.242650e-01 0.084 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.242650e-01 0.084 0 0
Generation of second messenger molecules R-HSA-202433 8.242650e-01 0.084 0 0
Cholesterol biosynthesis R-HSA-191273 8.264961e-01 0.083 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 8.341057e-01 0.079 0 0
Pyroptosis R-HSA-5620971 8.341057e-01 0.079 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 8.365163e-01 0.078 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 8.365163e-01 0.078 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 8.365163e-01 0.078 0 0
Other semaphorin interactions R-HSA-416700 8.365163e-01 0.078 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 8.365163e-01 0.078 0 0
PI Metabolism R-HSA-1483255 8.418747e-01 0.075 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.448532e-01 0.073 0 0
Intra-Golgi traffic R-HSA-6811438 8.448532e-01 0.073 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 8.464096e-01 0.072 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 8.513884e-01 0.070 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 8.513884e-01 0.070 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 8.513884e-01 0.070 0 0
Activation of the phototransduction cascade R-HSA-2485179 8.513884e-01 0.070 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 8.513884e-01 0.070 0 0
Carnitine synthesis R-HSA-71262 8.513884e-01 0.070 0 0
Atorvastatin ADME R-HSA-9754706 8.513884e-01 0.070 0 0
Virus Assembly and Release R-HSA-168268 8.513884e-01 0.070 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.543392e-01 0.068 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.567637e-01 0.067 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.567637e-01 0.067 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 8.633963e-01 0.064 0 0
Mitochondrial protein degradation R-HSA-9837999 8.647261e-01 0.063 0 0
Collagen formation R-HSA-1474290 8.647261e-01 0.063 0 0
Fibronectin matrix formation R-HSA-1566977 8.649084e-01 0.063 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 8.649084e-01 0.063 0 0
Passive transport by Aquaporins R-HSA-432047 8.649084e-01 0.063 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 8.649084e-01 0.063 0 0
Synthesis of PG R-HSA-1483148 8.649084e-01 0.063 0 0
Coenzyme A biosynthesis R-HSA-196783 8.649084e-01 0.063 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.669992e-01 0.062 0 0
Molecules associated with elastic fibres R-HSA-2129379 8.669992e-01 0.062 0 0
Innate Immune System R-HSA-168249 8.683375e-01 0.061 0 0
DAP12 interactions R-HSA-2172127 8.717994e-01 0.060 0 0
Leishmania parasite growth and survival R-HSA-9664433 8.730816e-01 0.059 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 8.730816e-01 0.059 0 0
Peptide hormone metabolism R-HSA-2980736 8.749523e-01 0.058 0 0
DNA strand elongation R-HSA-69190 8.765587e-01 0.057 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 8.765587e-01 0.057 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.765587e-01 0.057 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 8.771992e-01 0.057 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 8.771992e-01 0.057 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 8.771992e-01 0.057 0 0
Sulfide oxidation to sulfate R-HSA-1614517 8.771992e-01 0.057 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.771992e-01 0.057 0 0
Somitogenesis R-HSA-9824272 8.798150e-01 0.056 0 0
Peroxisomal protein import R-HSA-9033241 8.803238e-01 0.055 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 8.854805e-01 0.053 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 8.873816e-01 0.052 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 8.883724e-01 0.051 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 8.883724e-01 0.051 0 0
Synaptic adhesion-like molecules R-HSA-8849932 8.883724e-01 0.051 0 0
PKA activation R-HSA-163615 8.883724e-01 0.051 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 8.883724e-01 0.051 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 8.938015e-01 0.049 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.938015e-01 0.049 0 0
PPARA activates gene expression R-HSA-1989781 8.963455e-01 0.048 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 8.985295e-01 0.046 0 0
Germ layer formation at gastrulation R-HSA-9754189 8.985295e-01 0.046 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 8.985295e-01 0.046 0 0
Specification of the neural plate border R-HSA-9834899 8.985295e-01 0.046 0 0
The NLRP3 inflammasome R-HSA-844456 8.985295e-01 0.046 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 8.985295e-01 0.046 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 8.985295e-01 0.046 0 0
eNOS activation R-HSA-203615 9.015570e-01 0.045 0 0
RA biosynthesis pathway R-HSA-5365859 9.015570e-01 0.045 0 0
Metabolism of steroids R-HSA-8957322 9.041574e-01 0.044 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.041624e-01 0.044 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 9.077630e-01 0.042 0 0
Signaling by NODAL R-HSA-1181150 9.077630e-01 0.042 0 0
Creatine metabolism R-HSA-71288 9.077630e-01 0.042 0 0
Azathioprine ADME R-HSA-9748787 9.135540e-01 0.039 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 9.155063e-01 0.038 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.155438e-01 0.038 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 9.161568e-01 0.038 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 9.161568e-01 0.038 0 0
ERK/MAPK targets R-HSA-198753 9.161568e-01 0.038 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 9.161568e-01 0.038 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.161568e-01 0.038 0 0
Leishmania infection R-HSA-9658195 9.165996e-01 0.038 0 0
Parasitic Infection Pathways R-HSA-9824443 9.165996e-01 0.038 0 0
The phototransduction cascade R-HSA-2514856 9.191689e-01 0.037 0 0
Gastrulation R-HSA-9758941 9.205202e-01 0.036 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 9.237872e-01 0.034 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 9.237872e-01 0.034 0 0
Ribavirin ADME R-HSA-9755088 9.237872e-01 0.034 0 0
Glutathione synthesis and recycling R-HSA-174403 9.237872e-01 0.034 0 0
Metabolism of steroid hormones R-HSA-196071 9.259326e-01 0.033 0 0
Kidney development R-HSA-9830369 9.259326e-01 0.033 0 0
FCGR activation R-HSA-2029481 9.260965e-01 0.033 0 0
tRNA processing in the mitochondrion R-HSA-6785470 9.275820e-01 0.033 0 0
Elastic fibre formation R-HSA-1566948 9.275820e-01 0.033 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.294106e-01 0.032 0 0
Post-translational protein modification R-HSA-597592 9.303677e-01 0.031 0 0
Transcription of the HIV genome R-HSA-167172 9.303684e-01 0.031 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.307236e-01 0.031 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 9.307236e-01 0.031 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 9.307236e-01 0.031 0 0
Ethanol oxidation R-HSA-71384 9.307236e-01 0.031 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.333148e-01 0.030 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.370290e-01 0.028 0 0
Synthesis of UDP-N-acetyl-glucosamine R-HSA-446210 9.370290e-01 0.028 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.380140e-01 0.028 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 9.427609e-01 0.026 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 9.427609e-01 0.026 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.427609e-01 0.026 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.438783e-01 0.025 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 9.439857e-01 0.025 0 0
Dectin-2 family R-HSA-5621480 9.464019e-01 0.024 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 9.479713e-01 0.023 0 0
Alpha-oxidation of phytanate R-HSA-389599 9.479713e-01 0.023 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.479713e-01 0.023 0 0
Formation of the cornified envelope R-HSA-6809371 9.506400e-01 0.022 0 0
Extension of Telomeres R-HSA-180786 9.533919e-01 0.021 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.533919e-01 0.021 0 0
Regulation of beta-cell development R-HSA-186712 9.533919e-01 0.021 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.535668e-01 0.021 0 0
RAB geranylgeranylation R-HSA-8873719 9.565583e-01 0.019 0 0
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane R-HSA-83936 9.570133e-01 0.019 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 9.570133e-01 0.019 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.576245e-01 0.019 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.583879e-01 0.018 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 9.609270e-01 0.017 0 0
Formation of the Early Elongation Complex R-HSA-113418 9.609270e-01 0.017 0 0
Prednisone ADME R-HSA-9757110 9.609270e-01 0.017 0 0
Insulin receptor recycling R-HSA-77387 9.609270e-01 0.017 0 0
Inflammasomes R-HSA-622312 9.609270e-01 0.017 0 0
Integrin cell surface interactions R-HSA-216083 9.631620e-01 0.016 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.644846e-01 0.016 0 0
mRNA Capping R-HSA-72086 9.644846e-01 0.016 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.673144e-01 0.014 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.677185e-01 0.014 0 0
Neurotransmitter clearance R-HSA-112311 9.677185e-01 0.014 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.694972e-01 0.013 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 9.697551e-01 0.013 0 0
Cargo concentration in the ER R-HSA-5694530 9.706581e-01 0.013 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.708720e-01 0.013 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.716975e-01 0.012 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.720012e-01 0.012 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.723842e-01 0.012 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.736743e-01 0.012 0 0
G alpha (q) signalling events R-HSA-416476 9.742073e-01 0.011 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.755196e-01 0.011 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.779669e-01 0.010 0 0
COPII-mediated vesicle transport R-HSA-204005 9.788478e-01 0.009 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.788478e-01 0.009 0 0
G alpha (i) signalling events R-HSA-418594 9.788631e-01 0.009 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 9.799738e-01 0.009 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 9.799738e-01 0.009 0 0
Metabolism of porphyrins R-HSA-189445 9.803456e-01 0.009 0 0
Glucuronidation R-HSA-156588 9.813499e-01 0.008 0 0
SLC transporter disorders R-HSA-5619102 9.816665e-01 0.008 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.817418e-01 0.008 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.817979e-01 0.008 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.817979e-01 0.008 0 0
Paracetamol ADME R-HSA-9753281 9.828160e-01 0.008 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.834560e-01 0.007 0 0
Neurotransmitter release cycle R-HSA-112310 9.846048e-01 0.007 0 0
Collagen chain trimerization R-HSA-8948216 9.849632e-01 0.007 0 0
Synthesis of PA R-HSA-1483166 9.854198e-01 0.006 0 0
Extracellular matrix organization R-HSA-1474244 9.861437e-01 0.006 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 9.863331e-01 0.006 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.886201e-01 0.005 0 0
Metabolism of polyamines R-HSA-351202 9.886201e-01 0.005 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.887101e-01 0.005 0 0
Tryptophan catabolism R-HSA-71240 9.887101e-01 0.005 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.887101e-01 0.005 0 0
Collagen degradation R-HSA-1442490 9.895260e-01 0.005 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.906739e-01 0.004 0 0
Heme biosynthesis R-HSA-189451 9.906739e-01 0.004 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.911870e-01 0.004 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.919665e-01 0.004 0 0
Surfactant metabolism R-HSA-5683826 9.929985e-01 0.003 0 0
G alpha (s) signalling events R-HSA-418555 9.935805e-01 0.003 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.936366e-01 0.003 0 0
Nicotinate metabolism R-HSA-196807 9.936536e-01 0.003 0 0
O-linked glycosylation of mucins R-HSA-913709 9.941650e-01 0.003 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.942167e-01 0.003 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.942167e-01 0.003 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.952231e-01 0.002 0 0
ECM proteoglycans R-HSA-3000178 9.954688e-01 0.002 0 0
Metal ion assimilation from the host R-HSA-9638482 9.954688e-01 0.002 0 0
Metabolism of cofactors R-HSA-8978934 9.954688e-01 0.002 0 0
Transport of small molecules R-HSA-382551 9.956866e-01 0.002 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.961396e-01 0.002 0 0
Phospholipid metabolism R-HSA-1483257 9.963997e-01 0.002 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.971331e-01 0.001 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.974996e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.981773e-01 0.001 0 0
Glutathione conjugation R-HSA-156590 9.984837e-01 0.001 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.985046e-01 0.001 0 0
Complex I biogenesis R-HSA-6799198 9.988621e-01 0.000 0 0
Digestion and absorption R-HSA-8963743 9.988621e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.989270e-01 0.000 0 0
Glycosphingolipid biosynthesis R-HSA-9840309 9.989659e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.990525e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.993031e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.994073e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.994177e-01 0.000 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.994708e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.994978e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.995191e-01 0.000 0 0
Scavenging of heme from plasma R-HSA-2168880 9.995554e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.995796e-01 0.000 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 9.996029e-01 0.000 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.996054e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.996054e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.996392e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.996641e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.996947e-01 0.000 0 0
Interleukin-10 signaling R-HSA-6783783 9.997293e-01 0.000 0 0
Keratinization R-HSA-6805567 9.997450e-01 0.000 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.997540e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.997540e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.998835e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.998857e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999020e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999245e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999638e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999701e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999712e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999803e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999815e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999846e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999864e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999882e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999906e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999919e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999922e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999937e-01 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 9.999940e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999943e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999965e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999980e-01 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 9.999991e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999992e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999993e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999996e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999999e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999999e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999999e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways