PTK2

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
Y Sites Probabilities
Log-Odds: Y Sites / Y Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0MZ66 Y24 Sugiyama SHTN1 KIAA1598 sDEEKQLQLITsLKEQAIGEyEDLRAENQKTKEKCDKIRQE
A5A3E0 Y1062 Sugiyama POTEF A26C1B GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
O00401 Y256 GPS6|EPSD WASL FDMCGIsEAQLKDRETSKVIyDFIEKTGGVEAVKNELRRQA
O00410 Y820 Sugiyama IPO5 KPNB3 RANBP5 KLEEHFKNQELRQVKRQDEDyDEQVEEsLQDEDDNDVyILT
O00469 Y444 Sugiyama PLOD2 LWSNFWGALSPDGYYARsEDyVDIVQGNRVGVWNVPYMANV
O15357 Y1135 Sugiyama INPPL1 SHIP2 SGDDRSCSVLQMAKTLSEVDyAPAGPARSALLPGPLELQPP
O43164 Y63 Sugiyama PJA2 KIAA0438 RNF131 VSFKPCMTRHERSLGRAGDDyEVLELDDVPKENssGssPLD
O43237 Y184 Sugiyama DYNC1LI2 DNCLI2 LIC2 KIPPEKMRELERKFVKDFQDyMEPEEGCQGsPQRRGPLtsG
O43314 Y256 Sugiyama PPIP5K2 HISPPD1 KIAA0433 VIP2 YEEFMPTDGTDVKVytVGPDyAHAEARKSPALDGKVERDSE
O43390 Y376 Sugiyama HNRNPR HNRPR ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG
O43390 Y434 Sugiyama HNRNPR HNRPR KKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGG
O43390 Y435 Sugiyama HNRNPR HNRPR KRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGRGRGGGR
O43707 Y212 Sugiyama ACTN4 WKDGLAFNALIHRHRPELIEyDKLRKDDPVTNLNNAFEVAE
O43707 Y265 SIGNOR ACTN4 DIVNtARPDEKAIMTyVssFyHAFsGAQKAETAANRICKVL
O43707 Y31 SIGNOR ACTN4 yQyGPSSAGNGAGGGGSMGDyMAQEDDWDRDLLLDPAWEKQ
O43707 Y4 SIGNOR ACTN4 _________________MVDyHAANQSyQyGPSSAGNGAGG
O43719 Y650 Sugiyama HTATSF1 EEDtyEKVFDDEsDEKEDEEyADEKGLEAADKKAEEGDADE
O43823 Y311 Sugiyama AKAP8 AKAP95 RGFDRFGPDGTGRKRKQFQLyEEPDtKLARVDsEGDFsEND
O43852 Y185 Sugiyama CALU KDGDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNAD
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O43852 Y47 Sugiyama CALU RVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQLtPE
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60506 Y373 Sugiyama SYNCRIP HNRPQ NSAP1 ILEKAFsQFGKLERVKKLKDyAFIHFDERDGAVKAMEEMNG
O60568 Y444 Sugiyama PLOD3 LWSNFWGALSPDEYYARSEDyVELVQRKRVGVWNVPYISQA
O60664 Y95 Sugiyama PLIN3 M6PRBP1 TIP47 VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE
O60716 Y228 Sugiyama CTNND1 KIAA0384 yPPDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGy
O60716 Y280 Sugiyama CTNND1 KIAA0384 QPQVRVGGssVDLHRFHPEPyGLEDDQRsMGyDDLDyGMMs
O60739 Y30 Sugiyama EIF1B FDPFADATKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI
O60927 T75 Sugiyama PPP1R11 HCGV TCTE5 RRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHR
O60934 Y679 Sugiyama NBN NBS NBS1 P95 FRSLVIKNSTSRNPSGINDDyGQLKNFKKFKKVTYPGAGKL
O75116 Y936 Sugiyama ROCK2 KIAA0619 EITLTKADSEQLARsIAEEQysDLEKEKIMKELEIKEMMAR
O75208 Y93 Sugiyama COQ9 C16orf49 HSPC326 PSEC0129 PEssHsPPRYTDQGGEEEEDyEsEEQLQHRILTAALEFVPA
O75347 Y75 Sugiyama TBCA EILQEsRMMIPDCQRRLEAAyLDLQRILENEKDLEEAEEyK
O75369 Y902 Sugiyama FLNB FLN1L FLN3 TABP TAP VQFNsPLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLV
O75369 Y904 Sugiyama FLNB FLN1L FLN3 TABP TAP FNsPLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLVTY
O75508 Y191 PSP CLDN11 OSP OTM GGCVILCCAGDAQAFGENRFyyTAGsssPtHAKSAHV____
O75508 Y192 PSP CLDN11 OSP OTM GCVILCCAGDAQAFGENRFyyTAGsssPtHAKSAHV_____
O75718 Y390 Sugiyama CRTAP CASP ELyDFAKENIMDDDEGEVVEyVDDLLELEETS_________
O75962 Y2796 GPS6|SIGNOR|iPTMNet|EPSD|PSP TRIO VLGPGMDGIMVTWKDNFDSFySEVAELGRGRFSVVKKCDQK
O94906 Y105 Sugiyama PRPF6 C20orf14 AGSLFSSGPYEKDDEEADAIyAALDKRMDERRKERREQREK
O95340 Y182 Sugiyama PAPSS2 ATPSK2 GLYKRARAGEIKGFTGIDsDyEKPEtPERVLKTNLSTVSDC
O95347 Y938 Sugiyama SMC2 CAPE SMC2L1 PRO0324 SKHKREAEDGAAKVSKMLKDyDWINAERHLFGQPNSAYDFK
P00338 Y239 Sugiyama LDHA PIG19 GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL
P00491 Y249 Sugiyama PNP NP RHCGLRVFGFSLITNKVIMDyESLEKANHEEVLAAGKQAAQ
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P04406 Y314 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P04406 Y320 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04818 Y153 Sugiyama TYMS TS OK/SW-cl.29 PVyGFQWRHFGAEyRDMEsDysGQGVDQLQRVIDTIKtNPD
P06733 Y189 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD
P06733 Y270 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV
P06733 Y280 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07205 Y196 Sugiyama PGK2 PGKB MVGVNLPHKASGFLMKKELDyFAKALENPVRPFLAILGGAK
P07237 Y94 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK
P07355 Y188 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07355 Y199 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RAEDGsVIDyELIDQDARDLyDAGVKRKGTDVPKWIsIMTE
P07384 Y42 Sugiyama CAPN1 CANPL1 PIG30 RARELGLGRHENAIKyLGQDyEQLRVRCLQSGTLFRDEAFP
P07437 Y50 Sugiyama TUBB TUBB5 OK/SW-cl.56 IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP
P07814 Y827 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK
P07900 Y160 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPM
P07900 Y284 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P07900 Y309 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF
P07900 Y313 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG
P07900 Y61 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KEIFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLI
P07949 Y905 SIGNOR|EPSD|PSP RET CDHF12 CDHR16 PTC GRKMKIsDFGLsRDVyEEDsyVKRsQGRIPVKWMAIESLFD
P08238 Y155 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB SAYLVAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPI
P08238 Y276 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238 Y301 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF
P08238 Y305 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08238 Y484 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR
P08238 Y485 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK
P08238 Y56 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEIFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDII
P08708 Y84 Sugiyama RPS17 RPS17L GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09234 Y8 Sugiyama SNRPC _____________MPKFyCDyCDtyLtHDsPsVRKTHCSGR
P0CG38 Y1062 Sugiyama POTEI GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG39 Y1025 Sugiyama POTEJ GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P10809 Y385 Sugiyama HSPD1 HSP60 AQIEKRIQEIIEQLDVttsEyEKEKLNERLAKLsDGVAVLK
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 Y431 Sugiyama HSPA8 HSC70 HSP73 HSPA10 TVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMTK
P11142 Y443 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KQtQtFttysDNQPGVLIQVyEGERAMTKDNNLLGKFELTG
P11142 Y545 Sugiyama HSPA8 HSC70 HSP73 HSPA10 YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE
P11274 Y246 Sugiyama BCR BCR1 D22S11 ASRPPYRGRssEssCGVDGDyEDAELNPRFLKDNLIDANGG
P12277 Y125 Sugiyama CKB CKBB EHKTDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPH
P12277 Y39 Sugiyama CKB CKBB EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT
P12814 Y12 GPS6|SIGNOR|ELM|EPSD|PSP ACTN1 _________MDHyDsQQTNDyMQPEEDWDRDLLLDPAWEKQ
P12814 Y422 Sugiyama ACTN1 KAsIHEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEs
P13667 Y448 Sugiyama PDIA4 ERP70 ERP72 RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs
P13667 Y458 Sugiyama PDIA4 ERP70 ERP72 VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P14625 Y258 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GNTLGRGTTITLVLKEEAsDyLELDTIKNLVKKYSQFINFP
P15259 Y92 Sugiyama PGAM2 PGAMM DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV
P15374 Y141 Sugiyama UCHL3 KFLEEsVsMsPEERARyLENyDAIRVtHEtsAHEGQTEAPs
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17812 Y473 Sugiyama CTPS1 CTPS RRtLFQTKNsVMRKLyGDADyLEERHRHRFEVNPVWKKCLE
P17980 Y381 Sugiyama PSMC3 TBP1 ARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQCKAVCV
P17987 Y545 Sugiyama TCP1 CCT1 CCTA LRIDDLIKLHPESKDDKHGsyEDAVHsGALND_________
P18669 Y92 Sugiyama PGAM1 PGAMA CDABP0006 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
P18858 T183 Sugiyama LIG1 sLTEAEVAtEKEGEDGDQPttPPKPLKTSKAEtPtEsVsEP
P19174 Y771 Sugiyama PLCG1 PLC1 KLRYPINEEALEKIGTAEPDyGALyEGRNPGFyVEANPMPT
P19174 Y775 Sugiyama PLCG1 PLC1 PINEEALEKIGTAEPDyGALyEGRNPGFyVEANPMPTFKCA
P19387 Y142 Sugiyama POLR2C A-152E5.7 SNsPRVIPVTSRNRDNDPNDyVEQDDILIVKLRKGQELRLR
P20042 Y176 Sugiyama EIF2S2 EIF2B GIsFsNQtGPAWAGSERDytyEELLNRVFNIMREKNPDMVA
P21980 T368 Sugiyama TGM2 QPGYEGWQALDPTPQEKsEGtyCCGPVPVRAIKEGDLstKy
P22234 Y22 Sugiyama PAICS ADE2 AIRC PAIS AtAEVLNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAG
P22314 S56 Sugiyama UBA1 A1S9T UBE1 VPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSVL
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P23246 Y488 Sugiyama SFPQ PSF PMYQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQV
P23246 Y490 Sugiyama SFPQ PSF YQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEK
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P23528 Y85 Sugiyama CFL1 CFL DDPyAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWA
P23528 Y89 Sugiyama CFL1 CFL AtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPESA
P23588 Y609 Sugiyama EIF4B sASKyAALsVDGEDENEGEDyAE__________________
P24752 Y214 Sugiyama ACAT1 ACAT MAT GsCAENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNE
P25205 Y19 Sugiyama MCM3 __MAGtVVLDDVELREAQRDyLDFLDDEEDQGIyQsKVREL
P25398 Y127 Sugiyama RPS12 sCVVVKDYGKESQAKDVIEEyFKCKK_______________
P26010 Y753 EPSD|PSP ITGB7 GGIVAVGLGLVLAYRLSVEIyDRREySRFEKEQQQLNWKQD
P26010 Y758 EPSD|PSP ITGB7 VGLGLVLAYRLSVEIyDRREySRFEKEQQQLNWKQDsNPLY
P26640 Y601 Sugiyama VARS1 G7A VARS VARS2 VDMDFGTGAVKITPAHDQNDyEVGQRHGLEAIsIMDsRGAL
P27348 Y149 Sugiyama YWHAQ LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG
P27348 Y48 Sugiyama YWHAQ AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK
P27695 Y45 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 KSKTAAKKNDKEAAGEGPALyEDPPDQKtsPsGKPAtLKIC
P27797 Y338 Sugiyama CALR CRTC LWQVKSGTIFDNFLITNDEAyAEEFGNETWGVtKAAEKQMK
P29353 Y427 SIGNOR|Sugiyama SHC1 SHC SHCA RKQMPPPPPCPGRELFDDPsyVNVQNLDKARQAVGGAGPPN
P29401 Y481 Sugiyama TKT AANTKGICFIRTsRPENAIIyNNNEDFQVGQAKVVLKSKDD
P29692 S162 Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P30086 Y176 Sugiyama PEBP1 PBP PEBP KKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK_________
P30101 Y115 Sugiyama PDIA3 ERP57 ERP60 GRP58 yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA
P30101 Y264 Sugiyama PDIA3 ERP57 ERP60 GRP58 CPHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVM
P30101 Y265 Sugiyama PDIA3 ERP57 ERP60 GRP58 PHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVMM
P30101 Y269 Sugiyama PDIA3 ERP57 ERP60 GRP58 EDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVMMVAKK
P30101 Y67 Sugiyama PDIA3 ERP57 ERP60 GRP58 LMLVEFFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTA
P31153 Y242 Sugiyama MAT2A AMS2 MATA2 LKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLt
P31943 Y266 Sugiyama HNRNPH1 HNRPH HNRPH1 yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst
P31946 Y21 Sugiyama YWHAB MTMDKsELVQKAKLAEQAERyDDMAAAMKAVtEQGHELsNE
P31946 Y50 Sugiyama YWHAB AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P31947 Y48 Sugiyama SFN HME1 GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK
P32119 Y115 Sugiyama PRDX2 NKEFB TDPX1 GLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFIIDGK
P32121 Y404 Sugiyama ARRB2 ARB2 ARR2 DDIVFEDFARLRLKGMKDDDyDDQLC_______________
P32969 Y180 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________
P33176 Y516 Sugiyama KIF5B KNS KNS1 EELAVNyDQKSQEVEDKTKEyELLSDELNQKsATLAsIDAE
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34932 S31 Sugiyama HSPA4 APG2 HSPH2 QSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGAA
P35221 S641 Sugiyama CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35222 Y142 SIGNOR|PSP CTNNB1 CTNNB OK/SW-cl.35 PRO2286 VQRLAEPSQMLKHAVVNLINyQDDAELATRAIPELTKLLND
P36871 T426 Sugiyama PGM1 KQsVEDILKDHWQKYGRNFFtRyDyEEVEAEGANKMMKDLE
P36871 Y157 Sugiyama PGM1 GPAPEAITDKIFQISKTIEEyAVCPDLKVDLGVLGKQQFDL
P36871 Y428 Sugiyama PGM1 sVEDILKDHWQKYGRNFFtRyDyEEVEAEGANKMMKDLEAL
P36871 Y430 Sugiyama PGM1 EDILKDHWQKYGRNFFtRyDyEEVEAEGANKMMKDLEALMF
P36871 Y476 Sugiyama PGM1 GKQFSANDKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTD
P39019 Y48 Sugiyama RPS19 LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P41252 Y148 Sugiyama IARS1 IARS SAEWKSTVsRLGRWIDFDNDyKTLYPQFMESVWWVFKQLYD
P41567 Y30 Sugiyama EIF1 SUI1 FDPFADAsKGDDLLPAGTEDyIHIRIQQRNGRKtLttVQGI
P43243 Y202 Sugiyama MATR3 KIAA0723 RHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDD
P43243 Y219 Sugiyama MATR3 KIAA0723 VLDyDHGsRsQEsGyyDRMDyEDDRLRDGERCRDDsFFGEt
P47712 Y456 Sugiyama PLA2G4A CPLA2 PLA2G4 DsDDEsHEPKGtENEDAGsDyQsDNQASWIHRMIMALVSDS
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P49023 Y118 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama PXN sNPQDsVGsPCsRVGEEEHVysFPNKQKsAEPsPtVMstsL
P49023 Y31 GPS6|SIGNOR|ELM|iPTMNet|EPSD PXN LESTTSHISKRPVFLSEETPySYPTGNHTyQEIAVPPPVPP
P49327 Y2034 Sugiyama FASN FAS DYFVVFSSVSCGRGNAGQsNyGFANsAMERICEKRRHEGLP
P49327 Y45 Sugiyama FASN FAS NLIGGVDMVTDDDRRWKAGLyGLPRRsGKLKDLSRFDAsFF
P49736 Y234 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 VFKERIsDMCKENREsLVVNyEDLAAREHVLAYFLPEAPAE
P49840 Y279 Sugiyama GSK3A LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841 Y216 Sugiyama GSK3B LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P50402 Y94 Sugiyama EMD EDMD STA yDLPKKEDALLyQsKGyNDDyyEEsyFTTRTyGEPEsAGPS
P50991 Y269 Sugiyama CCT4 CCTD SRB IQFCLSAPKTDMDNQIVVSDyAQMDRVLREERAYILNLVKQ
P51580 Y13 Sugiyama TPMT ________MDGTRTSLDIEEysDtEVQKNQVLTLEEWQDKW
P51813 Y40 iPTMNet|EPSD BMX KMSPNNYKERLFVLTKTNLSyyEyDKMKRGSRKGSIEIKKI
P52565 Y156 Sugiyama ARHGDIA GDIA1 GVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYs
P54105 Y214 Sugiyama CLNS1A CLCI ICLN QsVssQYNMAGVRtEDsIRDyEDGMEVDttPtVAGQFEDAD
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P55072 Y805 Sugiyama VCP HEL-220 HEL-S-70 QGsGGGtGGsVYTEDNDDDLyG___________________
P55795 Y266 Sugiyama HNRNPH2 FTP3 HNRPH2 YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst
P56945 Y165 PSP BCAR1 CAS CASS1 CRKAS TSTFSKQTPHHPFPSPATDLyQVPPGPGGPAQDIyQVPPSA
P56945 Y234 Sugiyama BCAR1 CAS CASS1 CRKAS VPtRVGQGyVyEAAQPEQDEyDIPRHLLAPGPQDIyDVPPV
P56945 Y410 EPSD|PSP BCAR1 CAS CASS1 CRKAS PRERVLPPEVADGGVVDsGVyAVPPPAEREAPAEGKRLsAs
P56945 Y664 SIGNOR|iPTMNet|EPSD BCAR1 CAS CASS1 CRKAS tsQDsPDGQyENSEGGWMEDyDyVHLQGKEEFEKTQKELLE
P56945 Y666 SIGNOR|iPTMNet|EPSD BCAR1 CAS CASS1 CRKAS QDsPDGQyENSEGGWMEDyDyVHLQGKEEFEKTQKELLEKG
P60660 Y86 Sugiyama MYL6 DFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMG
P60660 Y89 Sugiyama MYL6 HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI
P60709 T297 Sugiyama ACTB TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709 Y218 Sugiyama ACTB ysFtttAEREIVRDIKEKLCyVALDFEQEMAtAAssssLEK
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y306 Sugiyama ACTB DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P60709 Y362 Sugiyama ACTB GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P61158 Y400 Sugiyama ACTR3 ARP3 GGSMLASTPEFYQVCHTKKDyEEIGPsICRHNPVFGVMs__
P61247 Y256 Sugiyama RPS3A FTE1 MFTL sssGKAtGDEtGAKVERADGyEPPVQEsV____________
P61981 Y20 Sugiyama YWHAG _MVDREQLVQKARLAEQAERyDDMAAAMKNVtELNEPLsNE
P61981 Y49 Sugiyama YWHAG NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P62191 Y184 Sugiyama PSMC1 MDDTDPLVTVMKVEKAPQETyADIGGLDNQIQEIKESVELP
P62191 Y439 Sugiyama PSMC1 FKKSKENVLyKKQEGtPEGLyL___________________
P62258 Y49 Sugiyama YWHAE KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62280 Y55 Sugiyama RPS11 RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG
P62333 Y328 Sugiyama PSMC6 SUG2 ARLDILKIHAGPITKHGEIDyEAIVKLSDGFNGADLRNVCT
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 Y144 Sugiyama RPL23A VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________
P62826 Y146 Sugiyama RAN ARA24 OK/SW-cl.81 IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR
P62906 Y11 Sugiyama RPL10A NEDD6 __________MSSKVsRDtLyEAVREVLHGNQRKRRKFLET
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P63000 Y64 EPSD|PSP RAC1 TC25 MIG5 VMVDGKPVNLGLWDTAGQEDyDRLRPLsYPQTDVFLICFSL
P63104 Y19 Sugiyama YWHAZ __MDKNELVQKAKLAEQAERyDDMAACMKsVtEQGAELsNE
P63104 Y48 Sugiyama YWHAZ sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK
P63261 T297 Sugiyama ACTG1 ACTG TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261 Y218 Sugiyama ACTG1 ACTG ysFtttAEREIVRDIKEKLCyVALDFEQEMAtAAssssLEK
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y306 Sugiyama ACTG1 ACTG DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P63261 Y362 Sugiyama ACTG1 ACTG GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 Y432 Sugiyama TUBA1B GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
P68363 Y451 Sugiyama TUBA1B DyEEVGVDsVEGEGEEEGEEy____________________
Q00169 Y140 Sugiyama PITPNA PITPN GTQENVHKLEPEAWKHVEAVyIDIADRSQVLSKDYKAEEDP
Q00839 Y260 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED
Q02809 Y434 Sugiyama PLOD1 LLH PLOD LWSNFWGALSADGYYARSEDyVDIVQGRRVGVWNVPYISNI
Q04446 Y657 Sugiyama GBE1 RVGTALPGKFKIVLDSDAAEyGGHQRLDHSTDFFSEAFEHN
Q04837 Y73 Sugiyama SSBP1 SSBP PVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPG
Q04917 Y49 Sugiyama YWHAH YWHA1 AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK
Q05397 S390 iPTMNet|EPSD|Sugiyama PTK2 FAK FAK1 LPSIPKLANSEKQGMRtHAVsVsEtDDyAEIIDEEDtytMP
Q05397 S392 Sugiyama PTK2 FAK FAK1 SIPKLANSEKQGMRtHAVsVsEtDDyAEIIDEEDtytMPST
Q05397 S677 Sugiyama PTK2 FAK FAK1 KCWAYDPSRRPRFTELKAQLsTILEEEKAQQEERMRMEsRR
Q05397 S850 iPTMNet|EPSD PTK2 FAK FAK1 ERFLKPDVRLsRGsIDREDGsLQGPIGNQHIyQPVGKPDPA
Q05397 S910 Sugiyama PTK2 FAK FAK1 sLssPADsyNEGVKLQPQEIsPPPtANLDRSNDKVyENVTG
Q05397 T394 Sugiyama PTK2 FAK FAK1 PKLANSEKQGMRtHAVsVsEtDDyAEIIDEEDtytMPSTRD
Q05397 Y397 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama PTK2 FAK FAK1 ANSEKQGMRtHAVsVsEtDDyAEIIDEEDtytMPSTRDYEI
Q05397 Y407 SIGNOR|EPSD|PSP|Sugiyama PTK2 FAK FAK1 HAVsVsEtDDyAEIIDEEDtytMPSTRDYEIQRERIELGRC
Q05397 Y570 Sugiyama PTK2 FAK FAK1 RNVLVSSNDCVKLGDFGLsRyMEDstyyKAsKGKLPIKWMA
Q05397 Y576 GPS6|SIGNOR|ELM|EPSD|PSP PTK2 FAK FAK1 SNDCVKLGDFGLsRyMEDstyyKAsKGKLPIKWMAPESINF
Q05397 Y577 GPS6|SIGNOR|ELM|EPSD|PSP PTK2 FAK FAK1 NDCVKLGDFGLsRyMEDstyyKAsKGKLPIKWMAPESINFR
Q05397 Y861 SIGNOR PTK2 FAK FAK1 RGsIDREDGsLQGPIGNQHIyQPVGKPDPAAPPKKPPRPGA
Q05397 Y925 iPTMNet|EPSD|Sugiyama PTK2 FAK FAK1 QPQEIsPPPtANLDRSNDKVyENVTGLVKAVIEMSSKIQPA
Q06830 Y116 Sugiyama PRDX1 PAGA PAGB TDPX2 GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK
Q07666 Y145 Sugiyama KHDRBS1 SAM68 LtAEIEKIQKGDSKKDDEENyLDLFsHKNMKLKERVLIPVK
Q12874 T475 Sugiyama SF3A3 SAP61 AVSLWAKLKLQKASERWQPDtEEEyEDssGNVVNKKTYEDL
Q12874 Y479 Sugiyama SF3A3 SAP61 WAKLKLQKASERWQPDtEEEyEDssGNVVNKKTYEDLKRQG
Q13098 S468 Sugiyama GPS1 COPS1 CSN1 RRAKAMMLRAAVLRNQIHVKsPPREGsQGELtPANsQsRMs
Q13263 Y133 Sugiyama TRIM28 KAP1 RNF96 TIF1B TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC
Q13263 Y242 Sugiyama TRIM28 KAP1 RNF96 TIF1B ESCDTLTCRDCQLNAHKDHQyQFLEDAVRNQRKLLAsLVKR
Q13442 Y70 Sugiyama PDAP1 HASPP28 DPKKEKKsLDsDEsEDEEDDyQQKRKGVEGLIDIENPNRVA
Q13561 S83 Sugiyama DCTN2 DCTN50 GTKGLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKY
Q13561 Y6 Sugiyama DCTN2 DCTN50 _______________MADPKyADLPGIARNEPDVYETSDLP
Q13561 Y86 Sugiyama DCTN2 DCTN50 GLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKYQRL
Q13765 T119 Sugiyama NACA HSD48 SKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAA
Q13765 Y120 Sugiyama NACA HSD48 KNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAAA
Q14155 S518 Sugiyama ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314 ERYLLLFPNVLLMLSASPRMsGFIyQGKLPtTGMTITKLED
Q14161 S590 Sugiyama GIT2 KIAA0148 sRDEsARRASRLEKQNstPEsDYDNTPNDMEPDGMGSSRKG
Q14257 Y311 Sugiyama RCN2 ERC55 NPDLFLtsEAtDyGRQLHDDyFyHDEL______________
Q14257 Y313 Sugiyama RCN2 ERC55 DLFLtsEAtDyGRQLHDDyFyHDEL________________
Q14451 Y188 GPS6|EPSD|PSP GRB7 QAAWPVGGDSRFVFRKNFAKyELFKssPHSLFPEKMVSSCL
Q14451 Y338 GPS6|EPSD|PSP GRB7 FCSEDEQSRTCWLAAFRLFKyGVQLYKNYQQAQSRHLHPsC
Q14457 Y233 EPSD|PSP BECN1 GT197 EKVQAEAERLDQEEAQyQREysEFKRQQLELDDELKSVENQ
Q14568 Y160 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERM
Q14568 Y283 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q15052 S488 Sugiyama ARHGEF6 COOL2 KIAA0006 PIXA ERYLMLFSNVLIMLSASPRMsGFIYQGKIPIAGTVVTRLDE
Q15054 Y119 Sugiyama POLD3 KIAA0039 HVYSIQKAMLKDSGPLFNTDyDILKSNLQNCSKFSAIQCAA
Q15149 Y3362 Sugiyama PLEC PLEC1 TGLsLLPLSEKAARARQEELySELQAREtFEKTPVEVPVGG
Q15181 Y169 Sugiyama PPA1 IOPPP PP EGETDWKVIAINVDDPDAANyNDINDVKRLKPGYLEATVDW
Q15293 Y278 Sugiyama RCN1 RCN LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE
Q15369 Y18 Sugiyama ELOC TCEB1 ___MDGEEKtyGGCEGPDAMyVKLISSDGHEFIVKREHALt
Q15369 Y8 Sugiyama ELOC TCEB1 _____________MDGEEKtyGGCEGPDAMyVKLISSDGHE
Q15459 Y456 Sugiyama SF3A1 SAP114 PRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAERRtDI
Q15650 T280 Sugiyama TRIP4 RQT4 EKAIKHKDKLLEFDRtsIRRtQVIDDESDyFASDSNQWLSK
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF6 Y32 Sugiyama HSP90AB4P KEIFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDII
Q58FF7 Y56 Sugiyama HSP90AB3P HSP90BC EEIFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FF8 Y198 Sugiyama HSP90AB2P HSP90BB DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q58FF8 Y260 Sugiyama HSP90AB2P HSP90BB VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW
Q58FF8 Y261 Sugiyama HSP90AB2P HSP90BB RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK
Q58FF8 Y56 Sugiyama HSP90AB2P HSP90BB KEIFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q5JTH9 Y1251 Sugiyama RRP12 KIAA0690 AEYKAKKAKGDVKKKGRPDPyAyIPLNRSKLNRRKKMKLQG
Q5T035 Y67 Sugiyama FAM120A2P C9orf129 SEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERSLPIN
Q5VV41 Y216 Sugiyama ARHGEF16 EPHEXIN4 NBR KKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQEsDDDILD
Q5XKE5 Y341 Sugiyama KRT79 K6L KB38 KRT6L QYELIAQRSRAEAEAWYQTKyEELQVTAGKHGDNLRDTKNE
Q6PCE3 S175 Sugiyama PGM2L1 BM32A PFVPYAVQKLKAVAGVMItAsHNRKEDNGYKVYWETGAQIT
Q6PFW1 Y267 Sugiyama PPIP5K1 HISPPD2A IP6K IPS1 KIAA0377 VIP1 YEEFMPTDGTDVKVytVGPDyAHAEARKSPALDGKVERDSE
Q6PKG0 Y633 Sugiyama LARP1 KIAA0731 LARP MEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVtQtPHyM
Q6S8J3 Y1062 Sugiyama POTEE A26C1A POTE2 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q6S8J3 Y918 Sugiyama POTEE A26C1A POTE2 YRFTTMAEREIVRDIKEKLCyVALDFEQEMAtAAssssLEK
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q71U36 Y432 Sugiyama TUBA1A TUBA3 GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
Q71U36 Y451 Sugiyama TUBA1A TUBA3 DyEEVGVDsVEGEGEEEGEEy____________________
Q7KZF4 Y476 Sugiyama SND1 TDRD11 SKGLATVIRYRQDDDQRssHyDELLAAEARAIKNGKGLHSK
Q86UK7 Y306 Sugiyama ZNF598 QFSYAPRHSRRNEGVVGGEDyEEVDRysRQGRVARAGTRGA
Q8N0Y7 Y92 Sugiyama PGAM4 PGAM3 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
Q8NEY8 Y58 Sugiyama PPHLN1 HSPC206 HSPC232 PPLLDRPGEGsYNRYYSHVDyRDYDEGRSFSHDRRSGPPHR
Q8NFD5 S1744 Sugiyama ARID1B BAF250B DAN15 KIAA1235 OSA2 ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI
Q8NI22 Y138 Sugiyama MCFD2 SDNSF INIIDGVLRDDDKNNDGyIDyAEFAKSLQ____________
Q8WVV9 Y34 Sugiyama HNRNPLL HNRPLL SRRF BLOCK24 EDREYESQAKRLKTEEGEIDysAEEGENRREAtPRGGGDGG
Q92882 Y207 Sugiyama OSTF1 sLLKKKQGTDAVRtLsNAEDyLDDEDsD_____________
Q96AE4 Y58 Sugiyama FUBP1 ARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQPDAKKV
Q96G46 T273 Sugiyama DUS3L GAPRQENCGAQQVPAGPGtstPPssPVRtCGPLtDEDVVRL
Q96P70 Y889 Sugiyama IPO9 IMP9 KIAA1192 RANBP9 HSPC273 HGINADDKRLQDIRVKGEEIysMDEGIRTRSKSAKNPERWT
Q96QK1 Y791 Sugiyama VPS35 MEM3 TCCCTA00141 HNtLEHLRLRREsPEsEGPIyEGLIL_______________
Q99426 Y98 Sugiyama TBCB CG22 CKAP1 PVDDGCRIHVIDHsGARLGEyEDVSRVEKytIsQEAyDQRQ
Q99459 Y459 Sugiyama CDC5L KIAA0432 PCDC5RP PGRtPLRDKLNINPEDGMADysDPsyVKQMERESREHLRLG
Q99848 Y265 Sugiyama EBNA1BP2 EBP2 NQKFGFGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPG
Q99961 Y315 GPS6|SIGNOR|ELM|EPSD|PSP SH3GL1 CNSA1 SH3D2B PIRtPSRSMPPLDQPSCKALyDFEPENDGELGFHEGDVITL
Q9BQE3 Y432 Sugiyama TUBA1C TUBA6 GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___
Q9BQE3 Y449 Sugiyama TUBA1C TUBA6 EKDyEEVGADsADGEDEGEEy____________________
Q9BRS2 T509 Sugiyama RIOK1 RIO1 QVEERtCsDsEDIGssECsDtDSEEQGDHARPKKHTTDPDI
Q9BUP3 Y62 Sugiyama HTATIP2 CC3 TIP30 GLFSKVTLIGRRKLTFDEEAyKNVNQEVVDFEKLDDYASAF
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BYX7 Y362 Sugiyama POTEKP ACTBL3 FKSG30 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q9H1E3 Y146 Sugiyama NUCKS1 NUCKS JC7 QEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPERKE
Q9H1E3 Y26 Sugiyama NUCKS1 NUCKS JC7 RNRKVVDysQFQEsDDADEDyGRDsGPPtKKIRSsPREAKN
Q9H4F8 Y407 Sugiyama SMOC1 FKRYVKKKAKPKKCARRFtDyCDLNKDKVISLPELKGCLGV
Q9H5V8 Y734 EPSD|PSP CDCP1 TRASK UNQ2486/PRO5773 EMPRQPKKFQKGRKDNDSHVyAVIEDTMVyGHLLQDSSGSF
Q9H6T3 Y90 Sugiyama RPAP3 KESSKKTREENTKNRIKsyDyEAWAKLDVDRILDELDKDDs
Q9H9S0 Y174 SIGNOR|EPSD|PSP NANOG QKNNWPKNSNGVTQKASAPTyPSLYSSYHQGCLVNPTGNLP
Q9H9S0 Y35 SIGNOR|EPSD|PSP NANOG EASDCKESSPMPVICGPEENyPSLQMSSAEMPHTETVsPLP
Q9NPI1 Y190 Sugiyama BRD7 BP75 CELTIX1 MIIKHPMDFSTMKEKIKNNDyQsIEELKDNFKLMCTNAMIY
Q9NRX4 Y116 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 AyGPAQHAISTEKIKAKyPDyEVtWANDGy___________
Q9NUL3 Y326 Sugiyama STAU2 MNPISRLAQIQQAKKEKEPDyVLLSERGMPRRREFVMQVKV
Q9NVS9 Y256 Sugiyama PNPO LPtGDsPLGPMTHRGEEDWLyERLAP_______________
Q9NYU2 Y449 Sugiyama UGGT1 GT UGCGL1 UGGT UGT1 UGTR IEGLSLHNVLKLNIQPsEADyAVDIRSPAISWVNNLEVDSR
Q9NZB2 Y418 Sugiyama FAM120A C9orf10 KIAA0183 OSSA SEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERssPIN
Q9UBR2 Y76 Sugiyama CTSZ YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA
Q9UK59 Y533 Sugiyama DBR1 LsDEHEPEQRKKIKRRNQAIyAAVDDDDDDAA_________
Q9UKV3 S388 Sugiyama ACIN1 ACINUS KIAA0670 EEEEREIKssQGLKEKsKsPsPPRLtEDRKKAsLVALPEQt
Q9UKV3 Y1086 Sugiyama ACIN1 ACINUS KIAA0670 RTALHGVKWPQSNPKFLCADyAEQDELDyHRGLLVDRPsEt
Q9UPR0 T584 Sugiyama PLCL2 KIAA1092 PLCE2 KILIKAKKLsSNCSGVEGDVtDEDEGAEMSQRMGKENMEQP
Q9UQL6 Y642 PSP HDAC5 KIAA0600 PGAGYKKLFSDAQPLQPLQVyQAPLSLATVPHQALGRTQss
Q9Y281 Y85 Sugiyama CFL2 EDPYtsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWA
Q9Y281 Y89 Sugiyama CFL2 tsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPESA
Q9Y2X7 Y321 EPSD|PSP GIT1 NHSTLVTERSAVPFLPVNPEySATRNQGRQKLARFNAREFA
Q9Y450 Y58 Sugiyama HBS1L HBS1 KIAA1038 AQFIYSRRDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQ
Q9Y490 Y1893 Sugiyama TLN1 KIAA1027 TLN TKsNtsPEELGPLANQLTsDyGRLAsEAKPAAVAAENEEIG
Q9Y4H2 Y632 Sugiyama IRS2 LCPsCPAssPKVAyHPyPEDyGDIEIGsHRssssNLGADDG
Q9Y4L1 Y759 Sugiyama HYOU1 GRP170 HSPH4 ORP150 AANsLEAFIFEtQDKLyQPEyQEVsTEEQREEISGKLSAAS
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y5S9 Y96 Sugiyama RBM8A RBM8 HSPC114 MDS014 FVTGVHEEATEEDIHDKFAEyGEIKNIHLNLDRRTGYLKGy
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 1.801696e-08 7.744 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 9.769851e-08 7.010 1 1
Apoptotic execution phase R-HSA-75153 1.008320e-06 5.996 1 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 4.292937e-06 5.367 0 0
EPH-Ephrin signaling R-HSA-2682334 6.763680e-06 5.170 1 0
Developmental Biology R-HSA-1266738 2.861000e-05 4.543 1 0
Ephrin signaling R-HSA-3928664 7.515287e-05 4.124 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.423688e-04 3.847 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.498398e-04 3.824 1 1
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.939123e-04 3.712 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.130781e-04 3.671 0 0
mRNA Splicing R-HSA-72172 3.072515e-04 3.513 0 0
Regulation of gene expression in beta cells R-HSA-210745 3.692155e-04 3.433 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 6.907562e-04 3.161 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.256923e-03 2.901 1 1
Signaling by Hippo R-HSA-2028269 1.256923e-03 2.901 0 0
Apoptosis R-HSA-109581 1.725157e-03 2.763 1 0
Signal Transduction R-HSA-162582 1.835262e-03 2.736 1 0
Formation of the cornified envelope R-HSA-6809371 2.119843e-03 2.674 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.493714e-03 2.603 0 0
Regulation of beta-cell development R-HSA-186712 3.931236e-03 2.405 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 4.160122e-03 2.381 0 0
Cell-Cell communication R-HSA-1500931 4.878524e-03 2.312 1 0
Programmed Cell Death R-HSA-5357801 5.809107e-03 2.236 1 0
Integrin signaling R-HSA-354192 6.232526e-03 2.205 1 1
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 5.917228e-03 2.228 0 0
TCR signaling R-HSA-202403 6.306952e-03 2.200 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 7.626651e-03 2.118 1 1
Mitotic Telophase/Cytokinesis R-HSA-68884 9.076698e-03 2.042 0 0
Generation of second messenger molecules R-HSA-202433 1.032998e-02 1.986 0 0
Nervous system development R-HSA-9675108 1.231566e-02 1.910 1 0
Signal regulatory protein family interactions R-HSA-391160 1.283211e-02 1.892 1 1
DCC mediated attractive signaling R-HSA-418885 1.421020e-02 1.847 1 1
Cell-extracellular matrix interactions R-HSA-446353 1.421020e-02 1.847 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.422140e-02 1.847 1 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.564930e-02 1.806 1 1
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 1.714816e-02 1.766 0 0
Axon guidance R-HSA-422475 1.901033e-02 1.721 1 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.977949e-02 1.704 0 0
Nephron development R-HSA-9831926 2.032024e-02 1.692 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.032024e-02 1.692 0 0
Keratinization R-HSA-6805567 2.098998e-02 1.678 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 2.371676e-02 1.625 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 2.768114e-02 1.558 0 0
Signaling by PTK6 R-HSA-8848021 3.027725e-02 1.519 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 3.027725e-02 1.519 0 0
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909 3.705755e-02 1.431 0 0
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046 3.705755e-02 1.431 0 0
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357 3.705755e-02 1.431 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 5.507145e-02 1.259 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 5.507145e-02 1.259 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 6.395246e-02 1.194 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 6.395246e-02 1.194 0 0
NTRK2 activates RAC1 R-HSA-9032759 6.395246e-02 1.194 0 0
NGF-independant TRKA activation R-HSA-187024 7.275054e-02 1.138 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 7.275054e-02 1.138 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 7.275054e-02 1.138 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 8.146646e-02 1.089 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 8.146646e-02 1.089 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 9.010100e-02 1.045 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 9.865489e-02 1.006 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 9.865489e-02 1.006 0 0
Type I hemidesmosome assembly R-HSA-446107 9.865489e-02 1.006 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 9.865489e-02 1.006 0 0
Lipophagy R-HSA-9613354 1.071289e-01 0.970 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.155237e-01 0.937 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.320789e-01 0.879 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.402407e-01 0.853 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 1.402407e-01 0.853 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 1.402407e-01 0.853 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.483263e-01 0.829 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.483263e-01 0.829 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.563362e-01 0.806 0 0
Erythropoietin activates RAS R-HSA-9027284 1.642714e-01 0.784 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.642714e-01 0.784 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 5.302129e-02 1.276 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 1.721324e-01 0.764 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 1.721324e-01 0.764 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 5.789713e-02 1.237 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 1.799199e-01 0.745 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 1.799199e-01 0.745 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 1.876347e-01 0.727 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 1.876347e-01 0.727 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.028486e-01 0.693 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 8.158120e-02 1.088 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.103490e-01 0.677 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 2.177794e-01 0.662 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 4.204129e-02 1.376 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 9.291268e-02 1.032 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 2.251403e-01 0.648 0 0
FGFR2 alternative splicing R-HSA-6803529 2.324323e-01 0.634 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 2.396562e-01 0.620 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 2.396562e-01 0.620 0 0
Termination of O-glycan biosynthesis R-HSA-977068 2.396562e-01 0.620 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 5.430800e-02 1.265 0 0
mRNA 3'-end processing R-HSA-72187 1.106904e-01 0.956 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.468126e-01 0.608 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.137351e-01 0.944 0 0
MET activates PTK2 signaling R-HSA-8874081 2.609251e-01 0.583 1 1
Signaling by NTRK2 (TRKB) R-HSA-9006115 2.678826e-01 0.572 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 2.678826e-01 0.572 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 2.678826e-01 0.572 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 2.747750e-01 0.561 0 0
Formation of the Early Elongation Complex R-HSA-113418 2.747750e-01 0.561 0 0
HIV elongation arrest and recovery R-HSA-167287 2.747750e-01 0.561 0 0
Pausing and recovery of HIV elongation R-HSA-167290 2.747750e-01 0.561 0 0
Late endosomal microautophagy R-HSA-9615710 2.816029e-01 0.550 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.883669e-01 0.540 0 0
Post-translational protein phosphorylation R-HSA-8957275 8.506319e-02 1.070 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 2.950677e-01 0.530 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 2.950677e-01 0.530 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.649485e-01 0.783 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.082818e-01 0.511 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.082818e-01 0.511 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 3.723897e-02 1.429 0 0
mRNA Capping R-HSA-72086 2.816029e-01 0.550 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 9.010100e-02 1.045 0 0
Nephrin family interactions R-HSA-373753 2.103490e-01 0.677 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 2.158423e-01 0.666 0 0
Regulation of gap junction activity R-HSA-191650 5.507145e-02 1.259 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 9.865489e-02 1.006 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 3.936354e-02 1.405 0 0
Formation of axial mesoderm R-HSA-9796292 1.483263e-01 0.829 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 2.678826e-01 0.572 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.103490e-01 0.677 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 2.883669e-01 0.540 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 2.992462e-01 0.524 0 0
Activation of HOX genes during differentiation R-HSA-5619507 2.992462e-01 0.524 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.749630e-01 0.757 0 0
MET promotes cell motility R-HSA-8875878 6.808883e-02 1.167 1 0
Myogenesis R-HSA-525793 2.609251e-01 0.583 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.716136e-01 0.765 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 1.563362e-01 0.806 0 0
UCH proteinases R-HSA-5689603 1.884608e-01 0.725 0 0
Syndecan interactions R-HSA-3000170 3.114586e-02 1.507 0 0
DAP12 signaling R-HSA-2424491 2.883669e-01 0.540 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 5.507145e-02 1.259 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 5.507145e-02 1.259 0 0
Activation of TRKA receptors R-HSA-187015 9.010100e-02 1.045 0 0
Regulation of CDH11 function R-HSA-9762292 1.155237e-01 0.937 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.155237e-01 0.937 0 0
NF-kB is activated and signals survival R-HSA-209560 1.320789e-01 0.879 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.402407e-01 0.853 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 1.642714e-01 0.784 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 1.952774e-01 0.709 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 2.028486e-01 0.693 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.388129e-01 0.858 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 2.574789e-01 0.589 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 2.888215e-01 0.539 0 0
Nucleotide Excision Repair R-HSA-5696398 3.027161e-01 0.519 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.952774e-01 0.709 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 2.816029e-01 0.550 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.468126e-01 0.608 0 0
Attachment and Entry R-HSA-9694614 2.251403e-01 0.648 0 0
Developmental Cell Lineages R-HSA-9734767 5.283687e-02 1.277 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.883669e-01 0.540 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.716136e-01 0.765 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.071289e-01 0.970 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.155237e-01 0.937 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.516046e-02 1.454 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.516046e-02 1.454 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 1.563362e-01 0.806 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.563362e-01 0.806 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.642714e-01 0.784 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 3.017058e-01 0.520 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.749630e-01 0.757 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 2.173018e-01 0.663 0 0
HS-GAG degradation R-HSA-2024096 3.017058e-01 0.520 0 0
Diseases of Immune System R-HSA-5260271 7.339052e-02 1.134 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 7.339052e-02 1.134 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.246797e-01 0.648 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.071289e-01 0.970 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 2.177794e-01 0.662 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.020968e-01 0.694 0 0
Signaling by Erythropoietin R-HSA-9006335 2.816029e-01 0.550 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.320506e-01 0.879 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.261225e-01 0.899 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.320506e-01 0.879 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 1.384620e-01 0.859 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 1.384620e-01 0.859 0 0
Netrin-1 signaling R-HSA-373752 8.719091e-02 1.060 1 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.876347e-01 0.727 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 2.678826e-01 0.572 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 7.275054e-02 1.138 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 9.865489e-02 1.006 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 1.320789e-01 0.879 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.402407e-01 0.853 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.642714e-01 0.784 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 7.072324e-02 1.150 0 0
Deadenylation of mRNA R-HSA-429947 2.468126e-01 0.608 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 2.468126e-01 0.608 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 2.747750e-01 0.561 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.388129e-01 0.858 0 0
Trafficking of AMPA receptors R-HSA-399719 2.950677e-01 0.530 0 0
Metabolism of RNA R-HSA-8953854 3.252113e-02 1.488 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.850723e-01 0.733 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.075482e-01 0.683 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.581367e-02 1.019 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.236721e-01 0.908 1 1
Signaling by ERBB2 in Cancer R-HSA-1227990 2.883669e-01 0.540 0 0
Termination of translesion DNA synthesis R-HSA-5656169 2.816029e-01 0.550 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.082818e-01 0.511 0 0
Cell junction organization R-HSA-446728 6.444012e-02 1.191 0 0
Signaling by VEGF R-HSA-194138 1.471720e-01 0.832 1 0
Gene expression (Transcription) R-HSA-74160 1.783305e-01 0.749 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 7.275054e-02 1.138 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 7.275054e-02 1.138 0 0
CHL1 interactions R-HSA-447041 9.010100e-02 1.045 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 1.238402e-01 0.907 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 2.251403e-01 0.648 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 2.609251e-01 0.583 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 2.678826e-01 0.572 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 2.883669e-01 0.540 0 0
Interleukin-1 signaling R-HSA-9020702 2.853426e-01 0.545 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.082818e-01 0.511 0 0
Platelet degranulation R-HSA-114608 1.515930e-01 0.819 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 6.292204e-02 1.201 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 2.816029e-01 0.550 0 0
Signaling by BMP R-HSA-201451 2.678826e-01 0.572 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.692179e-01 0.772 1 1
Platelet activation, signaling and aggregation R-HSA-76002 6.121012e-02 1.213 1 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.642714e-01 0.784 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.952774e-01 0.709 0 0
The NLRP3 inflammasome R-HSA-844456 2.028486e-01 0.693 0 0
Cargo concentration in the ER R-HSA-5694530 2.950677e-01 0.530 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.766261e-01 0.753 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.801570e-01 0.744 1 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.679301e-01 0.572 0 0
Frs2-mediated activation R-HSA-170968 1.483263e-01 0.829 0 0
p75NTR signals via NF-kB R-HSA-193639 1.642714e-01 0.784 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 2.853426e-01 0.545 1 1
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.485059e-01 0.828 0 0
ESR-mediated signaling R-HSA-8939211 9.752148e-02 1.011 1 0
Respiratory syncytial virus genome transcription R-HSA-9828642 1.563362e-01 0.806 0 0
Regulation of signaling by CBL R-HSA-912631 2.028486e-01 0.693 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.251403e-01 0.648 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 2.950677e-01 0.530 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.673898e-01 0.776 0 0
Deubiquitination R-HSA-5688426 1.202669e-01 0.920 0 0
Signaling by MET R-HSA-6806834 2.020968e-01 0.694 1 0
Influenza Infection R-HSA-168255 2.876868e-01 0.541 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.469693e-01 0.833 1 0
Nectin/Necl trans heterodimerization R-HSA-420597 6.395246e-02 1.194 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 2.539020e-01 0.595 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 2.609251e-01 0.583 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.020968e-01 0.694 0 0
Ub-specific processing proteases R-HSA-5689880 2.723775e-01 0.565 0 0
Other interleukin signaling R-HSA-449836 2.028486e-01 0.693 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 2.177794e-01 0.662 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.602917e-02 1.018 1 0
C-type lectin receptors (CLRs) R-HSA-5621481 2.672943e-01 0.573 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.748975e-01 0.561 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 3.027161e-01 0.519 0 0
Adaptive Immune System R-HSA-1280218 2.088103e-01 0.680 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.748975e-01 0.561 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.748975e-01 0.561 0 0
Transport of RCbl within the body R-HSA-9758890 1.238402e-01 0.907 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.402407e-01 0.853 0 0
Protein methylation R-HSA-8876725 1.642714e-01 0.784 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.799199e-01 0.745 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 2.028486e-01 0.693 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.082818e-01 0.511 0 0
RSV-host interactions R-HSA-9833110 2.992462e-01 0.524 0 0
Inflammasomes R-HSA-622312 2.747750e-01 0.561 0 0
Selective autophagy R-HSA-9663891 2.331379e-01 0.632 0 0
MAPK family signaling cascades R-HSA-5683057 2.666371e-01 0.574 1 0
Prolonged ERK activation events R-HSA-169893 1.721324e-01 0.764 0 0
SARS-CoV-2-host interactions R-HSA-9705683 2.079637e-01 0.682 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.175219e-01 0.930 1 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 4.600333e-02 1.337 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.952774e-01 0.709 0 0
GAB1 signalosome R-HSA-180292 1.952774e-01 0.709 0 0
Cytoprotection by HMOX1 R-HSA-9707564 2.123971e-01 0.673 0 0
Signaling by Nuclear Receptors R-HSA-9006931 2.955731e-01 0.529 1 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.396562e-01 0.620 1 1
Neurotransmitter release cycle R-HSA-112310 2.400815e-01 0.620 0 0
DNA Repair R-HSA-73894 2.901026e-01 0.537 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 2.324323e-01 0.634 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.324323e-01 0.634 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 1.195589e-01 0.922 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 2.099166e-01 0.678 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.106904e-01 0.956 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 2.539020e-01 0.595 0 0
Laminin interactions R-HSA-3000157 2.539020e-01 0.595 0 0
Downstream signal transduction R-HSA-186763 4.830194e-02 1.316 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 1.721324e-01 0.764 0 0
Differentiation of T cells R-HSA-9945266 1.721324e-01 0.764 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 2.747750e-01 0.561 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.017185e-01 0.993 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.783803e-01 0.555 0 0
Signaling by ERBB4 R-HSA-1236394 1.816928e-01 0.741 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 6.808883e-02 1.167 0 0
SARS-CoV-2 Infection R-HSA-9694516 2.702192e-01 0.568 0 0
Signaling by NOTCH3 R-HSA-9012852 1.198884e-01 0.921 0 0
MITF-M-dependent gene expression R-HSA-9856651 2.124125e-01 0.673 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.401767e-01 0.853 0 0
SARS-CoV Infections R-HSA-9679506 9.651437e-02 1.015 0 0
Kidney development R-HSA-9830369 1.583316e-01 0.800 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.789573e-01 0.747 0 0
Signaling by Interleukins R-HSA-449147 8.652330e-02 1.063 0 0
G0 and Early G1 R-HSA-1538133 3.017058e-01 0.520 0 0
Death Receptor Signaling R-HSA-73887 2.222148e-01 0.653 0 0
Signaling by PDGF R-HSA-186797 1.420282e-01 0.848 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 9.874041e-02 1.006 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.517671e-01 0.819 0 0
SARS-CoV-1 Infection R-HSA-9678108 2.774713e-01 0.557 0 0
Interleukin-12 signaling R-HSA-9020591 1.884608e-01 0.725 0 0
Interleukin-12 family signaling R-HSA-447115 2.296707e-01 0.639 0 0
Gene Silencing by RNA R-HSA-211000 3.096470e-01 0.509 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.096470e-01 0.509 0 0
Signaling by ALK in cancer R-HSA-9700206 3.096470e-01 0.509 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 3.131075e-01 0.504 0 0
Antigen processing-Cross presentation R-HSA-1236975 3.131075e-01 0.504 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.147963e-01 0.502 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 3.147963e-01 0.502 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.147963e-01 0.502 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.147963e-01 0.502 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 3.147963e-01 0.502 0 0
Heme degradation R-HSA-189483 3.147963e-01 0.502 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 3.165644e-01 0.500 0 0
Toll-like Receptor Cascades R-HSA-168898 3.184808e-01 0.497 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 3.200173e-01 0.495 0 0
MyD88-independent TLR4 cascade R-HSA-166166 3.200173e-01 0.495 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 3.212498e-01 0.493 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.212498e-01 0.493 0 0
Nuclear import of Rev protein R-HSA-180746 3.212498e-01 0.493 0 0
NOD1/2 Signaling Pathway R-HSA-168638 3.212498e-01 0.493 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 3.212498e-01 0.493 0 0
Mitophagy R-HSA-5205647 3.212498e-01 0.493 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.276430e-01 0.485 0 0
Signalling to ERKs R-HSA-187687 3.276430e-01 0.485 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 3.303507e-01 0.481 0 0
HS-GAG biosynthesis R-HSA-2022928 3.339763e-01 0.476 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.339763e-01 0.476 0 0
RUNX2 regulates bone development R-HSA-8941326 3.339763e-01 0.476 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 3.339763e-01 0.476 0 0
GPVI-mediated activation cascade R-HSA-114604 3.339763e-01 0.476 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 3.339763e-01 0.476 0 0
FGFR2 mutant receptor activation R-HSA-1839126 3.339763e-01 0.476 0 0
RNA Polymerase III Transcription R-HSA-74158 3.339763e-01 0.476 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.402503e-01 0.468 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.402503e-01 0.468 0 0
SLC-mediated transport of organic cations R-HSA-549127 3.402503e-01 0.468 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 3.406412e-01 0.468 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.464657e-01 0.460 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 3.464657e-01 0.460 0 0
PIP3 activates AKT signaling R-HSA-1257604 3.467331e-01 0.460 0 0
L1CAM interactions R-HSA-373760 3.474749e-01 0.459 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 3.493317e-01 0.457 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.526228e-01 0.453 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.526228e-01 0.453 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.526228e-01 0.453 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.526228e-01 0.453 0 0
RAS processing R-HSA-9648002 3.526228e-01 0.453 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 3.526228e-01 0.453 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.542855e-01 0.451 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 3.576816e-01 0.447 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.587223e-01 0.445 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.587223e-01 0.445 0 0
HIV Transcription Elongation R-HSA-167169 3.587223e-01 0.445 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.587223e-01 0.445 0 0
Attenuation phase R-HSA-3371568 3.587223e-01 0.445 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 3.587223e-01 0.445 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.587223e-01 0.445 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 3.587223e-01 0.445 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.587223e-01 0.445 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 3.587223e-01 0.445 0 0
Mitotic Prophase R-HSA-68875 3.610713e-01 0.442 0 0
Cellular response to heat stress R-HSA-3371556 3.644545e-01 0.438 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 3.644545e-01 0.438 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 3.647648e-01 0.438 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.647648e-01 0.438 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 3.647648e-01 0.438 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 3.647648e-01 0.438 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 3.707506e-01 0.431 0 0
HIV Transcription Initiation R-HSA-167161 3.707506e-01 0.431 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 3.707506e-01 0.431 0 0
MAP2K and MAPK activation R-HSA-5674135 3.707506e-01 0.431 0 0
Signaling by RAF1 mutants R-HSA-9656223 3.707506e-01 0.431 0 0
Intra-Golgi traffic R-HSA-6811438 3.707506e-01 0.431 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 3.712006e-01 0.430 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.712006e-01 0.430 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 3.766805e-01 0.424 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.766805e-01 0.424 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 3.774963e-01 0.423 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 3.825548e-01 0.417 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 3.825548e-01 0.417 0 0
Cell Cycle R-HSA-1640170 3.831495e-01 0.417 0 0
Mitotic Anaphase R-HSA-68882 3.851399e-01 0.414 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.876832e-01 0.412 0 0
DAP12 interactions R-HSA-2172127 3.883741e-01 0.411 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 3.883741e-01 0.411 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.883741e-01 0.411 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 3.883741e-01 0.411 0 0
Adherens junctions interactions R-HSA-418990 3.902241e-01 0.409 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.912644e-01 0.408 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 3.941389e-01 0.404 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 3.941389e-01 0.404 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 3.941389e-01 0.404 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 3.941389e-01 0.404 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.946275e-01 0.404 0 0
Immune System R-HSA-168256 3.954209e-01 0.403 1 0
Negative regulation of the PI3K/AKT network R-HSA-199418 3.978901e-01 0.400 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 3.998498e-01 0.398 0 0
Signaling downstream of RAS mutants R-HSA-9649948 3.998498e-01 0.398 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 3.998498e-01 0.398 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 3.998498e-01 0.398 0 0
Signaling by RAS mutants R-HSA-6802949 3.998498e-01 0.398 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 3.998498e-01 0.398 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.998498e-01 0.398 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 3.998498e-01 0.398 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 3.998498e-01 0.398 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 3.998498e-01 0.398 0 0
Viral Infection Pathways R-HSA-9824446 4.004013e-01 0.398 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.064161e-01 0.391 0 0
Transmission across Chemical Synapses R-HSA-112315 4.064161e-01 0.391 0 0
Degradation of CDH1 R-HSA-9766229 4.166634e-01 0.380 0 0
Gap junction trafficking and regulation R-HSA-157858 4.166634e-01 0.380 0 0
DNA Damage Bypass R-HSA-73893 4.166634e-01 0.380 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.221633e-01 0.375 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.221633e-01 0.375 0 0
HSF1-dependent transactivation R-HSA-3371571 4.276117e-01 0.369 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 4.276117e-01 0.369 0 0
The phototransduction cascade R-HSA-2514856 4.276117e-01 0.369 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.330090e-01 0.364 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 4.330090e-01 0.364 0 0
Neurexins and neuroligins R-HSA-6794361 4.330090e-01 0.364 0 0
PTEN Regulation R-HSA-6807070 4.337120e-01 0.363 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.383558e-01 0.358 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.383558e-01 0.358 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.383558e-01 0.358 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 4.401046e-01 0.356 1 1
Macroautophagy R-HSA-1632852 4.401046e-01 0.356 0 0
Translation initiation complex formation R-HSA-72649 4.436525e-01 0.353 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.436525e-01 0.353 0 0
Membrane Trafficking R-HSA-199991 4.451865e-01 0.351 0 0
Signaling by NOTCH R-HSA-157118 4.453415e-01 0.351 0 0
Intracellular signaling by second messengers R-HSA-9006925 4.463877e-01 0.350 0 0
Late Phase of HIV Life Cycle R-HSA-162599 4.464580e-01 0.350 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 4.464580e-01 0.350 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.488995e-01 0.348 0 0
HDACs deacetylate histones R-HSA-3214815 4.488995e-01 0.348 0 0
Paracetamol ADME R-HSA-9753281 4.488995e-01 0.348 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.496198e-01 0.347 0 0
FCERI mediated NF-kB activation R-HSA-2871837 4.527714e-01 0.344 0 0
RNA Polymerase II Transcription R-HSA-73857 4.536894e-01 0.343 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.540974e-01 0.343 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.540974e-01 0.343 0 0
NRAGE signals death through JNK R-HSA-193648 4.540974e-01 0.343 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 4.540974e-01 0.343 0 0
Signaling by EGFR R-HSA-177929 4.540974e-01 0.343 0 0
TNF signaling R-HSA-75893 4.540974e-01 0.343 0 0
Regulation of CDH1 Function R-HSA-9764561 4.592466e-01 0.338 0 0
Dectin-2 family R-HSA-5621480 4.592466e-01 0.338 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 4.592466e-01 0.338 0 0
Cytokine Signaling in Immune system R-HSA-1280215 4.603627e-01 0.337 0 0
Visual phototransduction R-HSA-2187338 4.621649e-01 0.335 0 0
Dual incision in TC-NER R-HSA-6782135 4.643475e-01 0.333 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 4.643475e-01 0.333 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 4.643475e-01 0.333 0 0
Signaling by NTRKs R-HSA-166520 4.652753e-01 0.332 0 0
Chromatin organization R-HSA-4839726 4.673453e-01 0.330 0 0
Gastrulation R-HSA-9758941 4.683752e-01 0.329 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 4.694007e-01 0.328 0 0
snRNP Assembly R-HSA-191859 4.694007e-01 0.328 0 0
Metabolism of non-coding RNA R-HSA-194441 4.694007e-01 0.328 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 4.694007e-01 0.328 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 4.694007e-01 0.328 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 4.694007e-01 0.328 0 0
Amino acid transport across the plasma membrane R-HSA-352230 4.694007e-01 0.328 0 0
Potential therapeutics for SARS R-HSA-9679191 4.714644e-01 0.327 0 0
Neutrophil degranulation R-HSA-6798695 4.716233e-01 0.326 0 0
Cell-cell junction organization R-HSA-421270 4.721839e-01 0.326 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 4.744064e-01 0.324 0 0
Signaling by ERBB2 R-HSA-1227986 4.744064e-01 0.324 0 0
Regulation of PTEN gene transcription R-HSA-8943724 4.744064e-01 0.324 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 4.744064e-01 0.324 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 4.745430e-01 0.324 0 0
Interleukin-1 family signaling R-HSA-446652 4.776109e-01 0.321 0 0
MAP kinase activation R-HSA-450294 4.793653e-01 0.319 0 0
Cell Cycle, Mitotic R-HSA-69278 4.797779e-01 0.319 0 0
DNA Double-Strand Break Repair R-HSA-5693532 4.806679e-01 0.318 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 4.837141e-01 0.315 0 0
NCAM signaling for neurite out-growth R-HSA-375165 4.842777e-01 0.315 1 1
tRNA processing in the nucleus R-HSA-6784531 4.842777e-01 0.315 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 4.842777e-01 0.315 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 4.842777e-01 0.315 0 0
Semaphorin interactions R-HSA-373755 4.891440e-01 0.311 0 0
Autophagy R-HSA-9612973 4.897735e-01 0.310 0 0
HIV Life Cycle R-HSA-162587 4.927866e-01 0.307 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 4.987402e-01 0.302 0 0
Signaling by TGFB family members R-HSA-9006936 5.017589e-01 0.300 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 5.034709e-01 0.298 0 0
DNA Double Strand Break Response R-HSA-5693606 5.081573e-01 0.294 0 0
SLC-mediated transport of amino acids R-HSA-9958863 5.081573e-01 0.294 0 0
Innate Immune System R-HSA-168249 5.120258e-01 0.291 1 0
Cellular response to chemical stress R-HSA-9711123 5.124771e-01 0.290 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 5.127998e-01 0.290 0 0
O-linked glycosylation of mucins R-HSA-913709 5.127998e-01 0.290 0 0
Transcription of the HIV genome R-HSA-167172 5.127998e-01 0.290 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.127998e-01 0.290 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 5.127998e-01 0.290 0 0
COPII-mediated vesicle transport R-HSA-204005 5.219545e-01 0.282 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.219545e-01 0.282 0 0
Interleukin-17 signaling R-HSA-448424 5.219545e-01 0.282 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.219545e-01 0.282 0 0
Generic Transcription Pathway R-HSA-212436 5.232223e-01 0.281 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 5.264675e-01 0.279 0 0
Retinoid metabolism and transport R-HSA-975634 5.264675e-01 0.279 0 0
Metabolism of porphyrins R-HSA-189445 5.264675e-01 0.279 0 0
M Phase R-HSA-68886 5.294197e-01 0.276 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 5.309382e-01 0.275 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 5.309382e-01 0.275 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 5.337772e-01 0.273 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 5.353670e-01 0.271 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 5.353670e-01 0.271 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.397543e-01 0.268 0 0
Signaling by FGFR in disease R-HSA-1226099 5.397543e-01 0.268 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 5.441003e-01 0.264 0 0
ISG15 antiviral mechanism R-HSA-1169408 5.441003e-01 0.264 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 5.450698e-01 0.264 1 0
RNA Polymerase I Promoter Clearance R-HSA-73854 5.484057e-01 0.261 0 0
Nuclear Receptor transcription pathway R-HSA-383280 5.568955e-01 0.254 0 0
RNA Polymerase I Transcription R-HSA-73864 5.568955e-01 0.254 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 5.568955e-01 0.254 0 0
G alpha (12/13) signalling events R-HSA-416482 5.568955e-01 0.254 0 0
Integrin cell surface interactions R-HSA-216083 5.568955e-01 0.254 0 0
Sensory processing of sound R-HSA-9659379 5.610808e-01 0.251 0 0
Signaling by FGFR2 R-HSA-5654738 5.652268e-01 0.248 0 0
PKR-mediated signaling R-HSA-9833482 5.652268e-01 0.248 0 0
Processing of DNA double-strand break ends R-HSA-5693607 5.693338e-01 0.245 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 5.693338e-01 0.245 0 0
Amyloid fiber formation R-HSA-977225 5.693338e-01 0.245 0 0
Diseases of glycosylation R-HSA-3781865 5.724661e-01 0.242 0 0
Peptide ligand-binding receptors R-HSA-375276 5.778009e-01 0.238 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 5.814253e-01 0.236 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 5.814253e-01 0.236 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 5.830873e-01 0.234 0 0
Oncogenic MAPK signaling R-HSA-6802957 5.853803e-01 0.233 0 0
Protein-protein interactions at synapses R-HSA-6794362 5.853803e-01 0.233 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 5.931794e-01 0.227 0 0
Post NMDA receptor activation events R-HSA-438064 5.970241e-01 0.224 0 0
Peptide chain elongation R-HSA-156902 6.008327e-01 0.221 0 0
ER-Phagosome pathway R-HSA-1236974 6.046055e-01 0.219 0 0
Downstream TCR signaling R-HSA-202424 6.083429e-01 0.216 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 6.120453e-01 0.213 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 6.120453e-01 0.213 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 6.137869e-01 0.212 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 6.157128e-01 0.211 0 0
Eukaryotic Translation Elongation R-HSA-156842 6.193459e-01 0.208 0 0
Collagen formation R-HSA-1474290 6.265101e-01 0.203 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 6.300417e-01 0.201 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 6.300417e-01 0.201 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.335402e-01 0.198 0 0
Eukaryotic Translation Termination R-HSA-72764 6.335402e-01 0.198 0 0
Telomere Maintenance R-HSA-157579 6.404390e-01 0.194 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.404390e-01 0.194 0 0
Hemostasis R-HSA-109582 6.406998e-01 0.193 1 0
Signaling by FGFR R-HSA-190236 6.438398e-01 0.191 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 6.450773e-01 0.190 0 0
Extracellular matrix organization R-HSA-1474244 6.461034e-01 0.190 0 0
FOXO-mediated transcription R-HSA-9614085 6.472086e-01 0.189 0 0
Glycolysis R-HSA-70171 6.505458e-01 0.187 0 0
ABC-family proteins mediated transport R-HSA-382556 6.505458e-01 0.187 0 0
Selenocysteine synthesis R-HSA-2408557 6.538517e-01 0.185 0 0
Regulation of endogenous retroelements R-HSA-9842860 6.571265e-01 0.182 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 6.571265e-01 0.182 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.571265e-01 0.182 0 0
PI Metabolism R-HSA-1483255 6.571265e-01 0.182 0 0
Viral mRNA Translation R-HSA-192823 6.603705e-01 0.180 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 6.635840e-01 0.178 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 6.635840e-01 0.178 0 0
Cellular responses to stimuli R-HSA-8953897 6.683755e-01 0.175 1 0
Vesicle-mediated transport R-HSA-5653656 6.709665e-01 0.173 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 6.761387e-01 0.170 0 0
HIV Infection R-HSA-162906 6.786725e-01 0.168 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 6.792040e-01 0.168 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 6.792040e-01 0.168 0 0
Neuronal System R-HSA-112316 6.809026e-01 0.167 0 0
rRNA processing R-HSA-72312 6.892847e-01 0.162 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 6.911795e-01 0.160 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 6.911795e-01 0.160 0 0
FCERI mediated MAPK activation R-HSA-2871796 6.911795e-01 0.160 0 0
Inositol phosphate metabolism R-HSA-1483249 6.911795e-01 0.160 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 6.941033e-01 0.159 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 6.969996e-01 0.157 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 7.055261e-01 0.151 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.083149e-01 0.150 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.083149e-01 0.150 0 0
Glucose metabolism R-HSA-70326 7.110775e-01 0.148 0 0
Homology Directed Repair R-HSA-5693538 7.138142e-01 0.146 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 7.218705e-01 0.142 0 0
Chromosome Maintenance R-HSA-73886 7.218705e-01 0.142 0 0
Host Interactions of HIV factors R-HSA-162909 7.297014e-01 0.137 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.369613e-01 0.133 0 0
G2/M Checkpoints R-HSA-69481 7.398030e-01 0.131 0 0
Infectious disease R-HSA-5663205 7.523829e-01 0.124 1 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.542563e-01 0.122 0 0
SLC-mediated transmembrane transport R-HSA-425407 7.576608e-01 0.121 0 0
O-linked glycosylation R-HSA-5173105 7.679118e-01 0.115 0 0
Ribosome-associated quality control R-HSA-9948299 7.701132e-01 0.113 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 7.744541e-01 0.111 1 1
Parasite infection R-HSA-9664407 7.744541e-01 0.111 1 0
Leishmania phagocytosis R-HSA-9664417 7.744541e-01 0.111 1 0
Parasitic Infection Pathways R-HSA-9824443 7.787188e-01 0.109 1 0
Leishmania infection R-HSA-9658195 7.787188e-01 0.109 1 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 7.802857e-01 0.108 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 7.890157e-01 0.103 0 0
ER to Golgi Anterograde Transport R-HSA-199977 7.910182e-01 0.102 0 0
S Phase R-HSA-69242 7.930018e-01 0.101 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.007511e-01 0.097 0 0
Arachidonate metabolism R-HSA-2142753 8.007511e-01 0.097 0 0
Protein localization R-HSA-9609507 8.026429e-01 0.095 0 0
HCMV Late Events R-HSA-9610379 8.100335e-01 0.091 0 0
Cellular response to starvation R-HSA-9711097 8.118378e-01 0.091 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 8.118378e-01 0.091 0 0
Separation of Sister Chromatids R-HSA-2467813 8.223114e-01 0.085 0 0
Selenoamino acid metabolism R-HSA-2408522 8.223114e-01 0.085 0 0
SLC transporter disorders R-HSA-5619102 8.273289e-01 0.082 0 0
tRNA processing R-HSA-72306 8.338007e-01 0.079 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 8.369456e-01 0.077 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 8.384958e-01 0.076 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 8.384958e-01 0.076 0 0
Cellular Senescence R-HSA-2559583 8.489449e-01 0.071 0 0
G2/M Transition R-HSA-69275 8.573649e-01 0.067 0 0
Mitotic G2-G2/M phases R-HSA-453274 8.600666e-01 0.065 0 0
Cellular responses to stress R-HSA-2262752 8.657688e-01 0.063 0 0
Mitotic Prometaphase R-HSA-68877 8.666005e-01 0.062 0 0
Glycosaminoglycan metabolism R-HSA-1630316 8.666005e-01 0.062 0 0
HCMV Early Events R-HSA-9609690 8.703745e-01 0.060 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 8.703745e-01 0.060 0 0
Co-inhibition by PD-1 R-HSA-389948 8.752418e-01 0.058 0 0
Sphingolipid metabolism R-HSA-428157 8.764300e-01 0.057 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 8.776070e-01 0.057 0 0
Signaling by ROBO receptors R-HSA-376176 8.787728e-01 0.056 0 0
Post-translational protein modification R-HSA-597592 8.793979e-01 0.056 0 0
Metabolism of vitamins and cofactors R-HSA-196854 8.797538e-01 0.056 0 0
Drug ADME R-HSA-9748784 8.959938e-01 0.048 0 0
Interferon Signaling R-HSA-913531 8.967401e-01 0.047 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.051097e-01 0.043 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.072937e-01 0.042 0 0
Chromatin modifying enzymes R-HSA-3247509 9.107823e-01 0.041 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.133129e-01 0.039 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.212442e-01 0.036 0 0
HCMV Infection R-HSA-9609646 9.234799e-01 0.035 0 0
Diseases of metabolism R-HSA-5668914 9.265873e-01 0.033 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.277638e-01 0.033 0 0
Cell Cycle Checkpoints R-HSA-69620 9.291381e-01 0.032 0 0
G alpha (q) signalling events R-HSA-416476 9.331072e-01 0.030 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.411476e-01 0.026 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 9.456529e-01 0.024 0 0
Disease R-HSA-1643685 9.474902e-01 0.023 1 0
Phospholipid metabolism R-HSA-1483257 9.503534e-01 0.022 0 0
GPCR ligand binding R-HSA-500792 9.802798e-01 0.009 0 0
GPCR downstream signalling R-HSA-388396 9.818801e-01 0.008 0 0
G alpha (i) signalling events R-HSA-418594 9.833385e-01 0.007 0 0
Fatty acid metabolism R-HSA-8978868 9.833385e-01 0.007 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.855950e-01 0.006 0 0
Translation R-HSA-72766 9.865414e-01 0.006 0 0
Transport of small molecules R-HSA-382551 9.868379e-01 0.006 0 0
Signaling by GPCR R-HSA-372790 9.904613e-01 0.004 0 0
Metabolism of proteins R-HSA-392499 9.941859e-01 0.003 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.978763e-01 0.001 0 0
Sensory Perception R-HSA-9709957 9.995889e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.999947e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.411093e-13 12.850 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 5.663019e-10 9.247 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.213436e-09 8.916 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.213436e-09 8.916 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.213436e-09 8.916 0 0
EPH-Ephrin signaling R-HSA-2682334 8.055009e-09 8.094 1 0
EPHB-mediated forward signaling R-HSA-3928662 6.497275e-08 7.187 1 1
Activation of BH3-only proteins R-HSA-114452 9.247259e-08 7.034 0 0
Gluconeogenesis R-HSA-70263 1.137026e-07 6.944 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.821479e-07 6.740 0 0
Axon guidance R-HSA-422475 2.246567e-07 6.648 1 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 3.531338e-07 6.452 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.589474e-07 6.181 0 0
Semaphorin interactions R-HSA-373755 6.702224e-07 6.174 0 0
Nervous system development R-HSA-9675108 6.232201e-07 6.205 1 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 7.850094e-07 6.105 1 1
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.377619e-06 5.861 1 0
SARS-CoV-2-host interactions R-HSA-9705683 1.365144e-06 5.865 0 0
Signaling by VEGF R-HSA-194138 1.622492e-06 5.790 1 0
Glycolysis R-HSA-70171 1.972538e-06 5.705 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.222241e-06 5.653 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.122209e-06 5.385 0 0
Regulation of CDH1 Function R-HSA-9764561 4.557178e-06 5.341 0 0
Glucose metabolism R-HSA-70326 7.414166e-06 5.130 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 8.048435e-06 5.094 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 8.048435e-06 5.094 0 0
Infectious disease R-HSA-5663205 9.557181e-06 5.020 1 0
AURKA Activation by TPX2 R-HSA-8854518 1.049131e-05 4.979 0 0
Signal Transduction R-HSA-162582 1.171747e-05 4.931 1 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.864915e-05 4.729 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.015574e-05 4.696 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.072295e-05 4.684 0 0
Centrosome maturation R-HSA-380287 2.176139e-05 4.662 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 2.209964e-05 4.656 0 0
Cell-Cell communication R-HSA-1500931 3.368039e-05 4.473 1 0
Smooth Muscle Contraction R-HSA-445355 3.674397e-05 4.435 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 4.294162e-05 4.367 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 4.155420e-05 4.381 0 0
Cell-extracellular matrix interactions R-HSA-446353 4.294162e-05 4.367 0 0
Platelet activation, signaling and aggregation R-HSA-76002 4.101103e-05 4.387 1 0
G2/M Transition R-HSA-69275 4.264904e-05 4.370 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.621731e-05 4.335 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 4.663043e-05 4.331 0 0
L1CAM interactions R-HSA-373760 5.192212e-05 4.285 0 0
Mitotic Prometaphase R-HSA-68877 5.627149e-05 4.250 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 6.556108e-05 4.183 0 0
Viral Infection Pathways R-HSA-9824446 6.286048e-05 4.202 0 0
SARS-CoV Infections R-HSA-9679506 6.272814e-05 4.203 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 7.802341e-05 4.108 0 0
SARS-CoV-2 Infection R-HSA-9694516 8.619341e-05 4.065 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.217568e-04 3.915 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.446590e-04 3.840 1 0
Gap junction trafficking R-HSA-190828 1.847501e-04 3.733 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.918122e-04 3.717 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 1.961539e-04 3.707 1 1
Signaling downstream of RAS mutants R-HSA-9649948 2.196254e-04 3.658 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.196254e-04 3.658 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.196254e-04 3.658 0 0
Signaling by RAS mutants R-HSA-6802949 2.196254e-04 3.658 0 0
Cytokine Signaling in Immune system R-HSA-1280215 2.033835e-04 3.692 0 0
Recycling pathway of L1 R-HSA-437239 2.388368e-04 3.622 0 0
Cilium Assembly R-HSA-5617833 2.593511e-04 3.586 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.776244e-04 3.557 0 0
Gap junction trafficking and regulation R-HSA-157858 2.810685e-04 3.551 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.029150e-04 3.519 0 0
CASP4 inflammasome assembly R-HSA-9948001 3.147808e-04 3.502 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 3.926312e-04 3.406 0 0
Hemostasis R-HSA-109582 4.059062e-04 3.392 1 0
Immune System R-HSA-168256 4.199709e-04 3.377 1 0
Manipulation of host energy metabolism R-HSA-9636667 4.275573e-04 3.369 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 4.375516e-04 3.359 0 0
Programmed Cell Death R-HSA-5357801 4.410743e-04 3.355 1 0
Apoptosis R-HSA-109581 4.642350e-04 3.333 1 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 5.381991e-04 3.269 0 0
Muscle contraction R-HSA-397014 5.483202e-04 3.261 0 0
G2/M Checkpoints R-HSA-69481 5.763081e-04 3.239 0 0
Disease R-HSA-1643685 6.750648e-04 3.171 1 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 6.838906e-04 3.165 0 0
Signaling by Interleukins R-HSA-449147 7.152160e-04 3.146 0 0
Striated Muscle Contraction R-HSA-390522 7.185415e-04 3.144 0 0
Signal regulatory protein family interactions R-HSA-391160 8.059839e-04 3.094 1 1
Non-canonical inflammasome activation R-HSA-9686114 8.059839e-04 3.094 0 0
Cell junction organization R-HSA-446728 8.263119e-04 3.083 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 8.537949e-04 3.069 0 0
GPVI-mediated activation cascade R-HSA-114604 9.379298e-04 3.028 0 0
Cell Cycle R-HSA-1640170 9.443434e-04 3.025 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.020479e-03 2.991 0 0
Membrane Trafficking R-HSA-199991 1.030693e-03 2.987 0 0
Axonal growth stimulation R-HSA-209563 1.172367e-03 2.931 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.083322e-03 2.965 1 1
MAPK family signaling cascades R-HSA-5683057 1.138180e-03 2.944 1 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.208954e-03 2.918 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.278565e-03 2.893 1 0
Generation of second messenger molecules R-HSA-202433 1.298618e-03 2.887 0 0
Aggrephagy R-HSA-9646399 1.298618e-03 2.887 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.402025e-03 2.853 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 1.429773e-03 2.845 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.511043e-03 2.821 0 0
MAP2K and MAPK activation R-HSA-5674135 1.511043e-03 2.821 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.622029e-03 2.790 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.625831e-03 2.789 0 0
Potential therapeutics for SARS R-HSA-9679191 1.513235e-03 2.820 0 0
Signaling by SCF-KIT R-HSA-1433557 1.746546e-03 2.758 0 0
Developmental Biology R-HSA-1266738 1.576555e-03 2.802 1 0
Interleukin-12 signaling R-HSA-9020591 1.579924e-03 2.801 0 0
Cell Cycle Checkpoints R-HSA-69620 1.907942e-03 2.719 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.053297e-03 2.688 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 2.053297e-03 2.688 0 0
Organelle biogenesis and maintenance R-HSA-1852241 2.177217e-03 2.662 0 0
IRS activation R-HSA-74713 2.268297e-03 2.644 0 0
M Phase R-HSA-68886 2.357987e-03 2.627 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.449285e-03 2.611 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 2.559974e-03 2.592 0 0
Extracellular matrix organization R-HSA-1474244 2.731923e-03 2.564 0 0
Post NMDA receptor activation events R-HSA-438064 2.804072e-03 2.552 0 0
Interleukin-12 family signaling R-HSA-447115 2.804072e-03 2.552 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.114269e-03 2.507 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 3.423041e-03 2.466 0 0
Platelet degranulation R-HSA-114608 3.049987e-03 2.516 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 3.375797e-03 2.472 0 0
Vesicle-mediated transport R-HSA-5653656 3.605810e-03 2.443 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.171599e-03 2.499 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.171599e-03 2.499 0 0
SARS-CoV-1 Infection R-HSA-9678108 3.355411e-03 2.474 0 0
STAT5 Activation R-HSA-9645135 3.701503e-03 2.432 0 0
Nef and signal transduction R-HSA-164944 3.701503e-03 2.432 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 3.701503e-03 2.432 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 3.713529e-03 2.430 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 3.849709e-03 2.415 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.930567e-03 2.406 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 4.540367e-03 2.343 0 0
FOXO-mediated transcription R-HSA-9614085 4.965075e-03 2.304 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.106687e-03 2.292 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 5.407163e-03 2.267 0 0
Formation of annular gap junctions R-HSA-196025 5.458538e-03 2.263 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 5.458538e-03 2.263 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 5.548838e-03 2.256 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 5.639285e-03 2.249 0 0
Signaling by PTK6 R-HSA-8848021 5.639285e-03 2.249 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 6.454398e-03 2.190 0 0
Gap junction degradation R-HSA-190873 6.454398e-03 2.190 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 6.207748e-03 2.207 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.454398e-03 2.190 0 0
IGF1R signaling cascade R-HSA-2428924 5.918969e-03 2.228 0 0
Insulin receptor signalling cascade R-HSA-74751 5.918969e-03 2.228 0 0
DAP12 signaling R-HSA-2424491 5.666357e-03 2.247 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 6.454398e-03 2.190 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 7.051544e-03 2.152 0 0
Cell-cell junction organization R-HSA-421270 5.808739e-03 2.236 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 5.813458e-03 2.236 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 6.207748e-03 2.207 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 7.340028e-03 2.134 0 0
PI3K/AKT activation R-HSA-198203 7.526350e-03 2.123 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 7.526350e-03 2.123 0 0
Signal attenuation R-HSA-74749 7.526350e-03 2.123 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 7.526350e-03 2.123 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 7.585470e-03 2.120 0 0
Gap junction assembly R-HSA-190861 8.076911e-03 2.093 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 8.494109e-03 2.071 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 8.620760e-03 2.064 1 1
vRNP Assembly R-HSA-192905 8.672822e-03 2.062 0 0
PECAM1 interactions R-HSA-210990 8.672822e-03 2.062 0 0
Drug resistance of FLT3 mutants R-HSA-9702506 9.825653e-03 2.008 0 0
FLT3 mutants bind TKIs R-HSA-9702509 9.825653e-03 2.008 0 0
ponatinib-resistant FLT3 mutants R-HSA-9702614 9.825653e-03 2.008 0 0
KW2449-resistant FLT3 mutants R-HSA-9702569 9.825653e-03 2.008 0 0
lestaurtinib-resistant FLT3 mutants R-HSA-9702596 9.825653e-03 2.008 0 0
linifanib-resistant FLT3 mutants R-HSA-9702998 9.825653e-03 2.008 0 0
sunitinib-resistant FLT3 mutants R-HSA-9702632 9.825653e-03 2.008 0 0
pexidartinib-resistant FLT3 mutants R-HSA-9702605 9.825653e-03 2.008 0 0
sorafenib-resistant FLT3 mutants R-HSA-9702624 9.825653e-03 2.008 0 0
tamatinib-resistant FLT3 mutants R-HSA-9703009 9.825653e-03 2.008 0 0
quizartinib-resistant FLT3 mutants R-HSA-9702620 9.825653e-03 2.008 0 0
gilteritinib-resistant FLT3 mutants R-HSA-9702590 9.825653e-03 2.008 0 0
crenolanib-resistant FLT3 mutants R-HSA-9702581 9.825653e-03 2.008 0 0
tandutinib-resistant FLT3 mutants R-HSA-9702636 9.825653e-03 2.008 0 0
midostaurin-resistant FLT3 mutants R-HSA-9702600 9.825653e-03 2.008 0 0
semaxanib-resistant FLT3 mutants R-HSA-9702577 9.825653e-03 2.008 0 0
MET promotes cell motility R-HSA-8875878 1.037901e-02 1.984 1 0
HSF1 activation R-HSA-3371511 9.185619e-03 2.037 0 0
Leishmania infection R-HSA-9658195 1.053479e-02 1.977 1 0
Parasitic Infection Pathways R-HSA-9824443 1.053479e-02 1.977 1 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 9.892265e-03 2.005 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.138269e-02 1.944 0 0
RET signaling R-HSA-8853659 9.185619e-03 2.037 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.027680e-02 1.988 0 0
Adherens junctions interactions R-HSA-418990 9.836746e-03 2.007 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.171113e-02 1.931 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.041227e-02 1.982 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 8.826601e-03 2.054 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.302432e-02 1.885 0 0
Innate Immune System R-HSA-168249 1.390671e-02 1.857 1 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.397327e-02 1.855 0 0
Cell Cycle, Mitotic R-HSA-69278 1.410308e-02 1.851 0 0
Netrin-1 signaling R-HSA-373752 1.523805e-02 1.817 1 0
DAP12 interactions R-HSA-2172127 1.523805e-02 1.817 0 0
DCC mediated attractive signaling R-HSA-418885 1.546957e-02 1.811 1 1
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.546957e-02 1.811 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.562187e-02 1.806 0 0
Selective autophagy R-HSA-9663891 1.616172e-02 1.792 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.765117e-02 1.753 0 0
Intraflagellar transport R-HSA-5620924 1.850012e-02 1.733 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.865742e-02 1.729 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 1.865742e-02 1.729 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.898402e-02 1.722 0 0
Signaling by Insulin receptor R-HSA-74752 1.903620e-02 1.720 0 0
Protein folding R-HSA-391251 1.903620e-02 1.720 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.977866e-02 1.704 0 0
PI3K Cascade R-HSA-109704 2.026511e-02 1.693 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.034618e-02 1.692 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.034618e-02 1.692 0 0
Signaling by Hippo R-HSA-2028269 2.034618e-02 1.692 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 2.042824e-02 1.690 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 2.042859e-02 1.690 1 1
Parasite infection R-HSA-9664407 2.042859e-02 1.690 1 0
Leishmania phagocytosis R-HSA-9664417 2.042859e-02 1.690 1 0
Neutrophil degranulation R-HSA-6798695 2.095500e-02 1.679 0 0
Ephrin signaling R-HSA-3928664 2.209632e-02 1.656 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.209632e-02 1.656 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.209632e-02 1.656 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 2.211972e-02 1.655 0 0
COPI-mediated anterograde transport R-HSA-6807878 2.220863e-02 1.653 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 2.919006e-02 1.535 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.577533e-02 1.589 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.770157e-02 1.557 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.770157e-02 1.557 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 3.172103e-02 1.499 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.172103e-02 1.499 0 0
mRNA Splicing R-HSA-72172 2.453559e-02 1.610 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.979864e-02 1.526 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.381173e-02 1.471 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.189648e-02 1.496 0 0
TCR signaling R-HSA-202403 3.357513e-02 1.474 0 0
IRS-mediated signalling R-HSA-112399 2.714846e-02 1.566 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 2.361883e-02 1.627 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.792081e-02 1.554 1 0
Rap1 signalling R-HSA-392517 2.390648e-02 1.621 0 0
Signal transduction by L1 R-HSA-445144 2.577533e-02 1.589 0 0
Signaling by ERBB2 R-HSA-1227986 3.043394e-02 1.517 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 2.568585e-02 1.590 1 1
Ribavirin ADME R-HSA-9755088 2.968389e-02 1.527 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.425800e-02 1.615 0 0
Autophagy R-HSA-9612973 2.997200e-02 1.523 0 0
Signaling by NTRKs R-HSA-166520 2.518801e-02 1.599 0 0
Kinesins R-HSA-983189 3.043394e-02 1.517 0 0
Syndecan interactions R-HSA-3000170 3.381173e-02 1.471 0 0
Mitotic Anaphase R-HSA-68882 3.053838e-02 1.515 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.107831e-02 1.508 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.770157e-02 1.557 0 0
Growth hormone receptor signaling R-HSA-982772 3.381173e-02 1.471 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.381173e-02 1.471 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.107614e-02 1.508 0 0
Signaling by ALK in cancer R-HSA-9700206 3.107614e-02 1.508 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 2.316184e-02 1.635 0 0
Separation of Sister Chromatids R-HSA-2467813 3.529388e-02 1.452 0 0
Adaptive Immune System R-HSA-1280218 3.529759e-02 1.452 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 3.595476e-02 1.444 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.595476e-02 1.444 0 0
Neurodegenerative Diseases R-HSA-8863678 3.595476e-02 1.444 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.595476e-02 1.444 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 3.708478e-02 1.431 1 0
PIP3 activates AKT signaling R-HSA-1257604 3.778559e-02 1.423 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.814889e-02 1.419 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.814889e-02 1.419 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.814889e-02 1.419 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 3.873067e-02 1.412 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 3.873067e-02 1.412 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 3.873067e-02 1.412 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 3.873067e-02 1.412 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 3.873067e-02 1.412 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 3.985071e-02 1.400 0 0
Cellular responses to stimuli R-HSA-8953897 3.995100e-02 1.398 1 0
MET activates PTK2 signaling R-HSA-8874081 4.039294e-02 1.394 1 1
Signaling by EGFR in Cancer R-HSA-1643713 4.039294e-02 1.394 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.268572e-02 1.370 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.268572e-02 1.370 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.268572e-02 1.370 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 4.268572e-02 1.370 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 4.417704e-02 1.355 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.431185e-02 1.353 0 0
Cellular response to heat stress R-HSA-3371556 4.572689e-02 1.340 0 0
Signaling by Erythropoietin R-HSA-9006335 4.741285e-02 1.324 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 4.741285e-02 1.324 0 0
MHC class II antigen presentation R-HSA-2132295 4.778756e-02 1.321 0 0
PLC-gamma1 signalling R-HSA-167021 4.817811e-02 1.317 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 4.817811e-02 1.317 0 0
MET interacts with TNS proteins R-HSA-8875513 4.817811e-02 1.317 0 0
Interferon Signaling R-HSA-913531 4.823610e-02 1.317 0 0
Signaling by NOTCH4 R-HSA-9013694 4.837818e-02 1.315 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.982068e-02 1.303 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 4.984494e-02 1.302 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 4.984494e-02 1.302 0 0
Interleukin-37 signaling R-HSA-9008059 4.984494e-02 1.302 0 0
Bacterial Infection Pathways R-HSA-9824439 5.231843e-02 1.281 0 0
Downstream signal transduction R-HSA-186763 5.232122e-02 1.281 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 5.427423e-02 1.265 0 0
Signaling by MET R-HSA-6806834 5.734357e-02 1.242 1 0
PKR-mediated signaling R-HSA-9833482 5.734357e-02 1.242 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 5.740202e-02 1.241 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 5.753327e-02 1.240 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 5.753327e-02 1.240 0 0
Nucleotide catabolism defects R-HSA-9735786 5.753327e-02 1.240 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 5.753327e-02 1.240 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 5.753327e-02 1.240 0 0
NADE modulates death signalling R-HSA-205025 5.753327e-02 1.240 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 6.002661e-02 1.222 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 6.679705e-02 1.175 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.679705e-02 1.175 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 7.597035e-02 1.119 0 0
Erythropoietin activates STAT5 R-HSA-9027283 8.505404e-02 1.070 0 0
SOS-mediated signalling R-HSA-112412 9.404898e-02 1.027 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.404898e-02 1.027 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 1.029560e-01 0.987 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.029560e-01 0.987 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.029560e-01 0.987 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.205099e-01 0.919 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.205099e-01 0.919 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 6.264672e-02 1.203 0 0
RAF activation R-HSA-5673000 6.264672e-02 1.203 0 0
FLT3 Signaling R-HSA-9607240 8.217697e-02 1.085 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.029560e-01 0.987 0 0
Regulation of CDH11 function R-HSA-9762292 1.205099e-01 0.919 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.205099e-01 0.919 0 0
FLT3 signaling in disease R-HSA-9682385 6.804707e-02 1.167 0 0
PTK6 Expression R-HSA-8849473 9.404898e-02 1.027 0 0
Calcineurin activates NFAT R-HSA-2025928 1.117761e-01 0.952 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 8.806066e-02 1.055 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 7.597035e-02 1.119 0 0
HCMV Early Events R-HSA-9609690 6.314265e-02 1.200 0 0
DAG and IP3 signaling R-HSA-1489509 9.711193e-02 1.013 0 0
NTRK2 activates RAC1 R-HSA-9032759 6.679705e-02 1.175 0 0
Cam-PDE 1 activation R-HSA-111957 7.597035e-02 1.119 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 7.597035e-02 1.119 0 0
eNOS activation R-HSA-203615 6.264672e-02 1.203 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.286618e-02 1.082 0 0
PTK6 Activates STAT3 R-HSA-8849474 6.679705e-02 1.175 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.117761e-01 0.952 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 7.359506e-02 1.133 0 0
LDL remodeling R-HSA-8964041 9.404898e-02 1.027 0 0
ARMS-mediated activation R-HSA-170984 1.117761e-01 0.952 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.205099e-01 0.919 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 8.123014e-02 1.090 0 0
Developmental Cell Lineages R-HSA-9734767 6.291826e-02 1.201 0 0
Co-inhibition by BTLA R-HSA-9927353 6.679705e-02 1.175 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 1.117761e-01 0.952 0 0
HSF1-dependent transactivation R-HSA-3371571 1.159433e-01 0.936 0 0
Signaling by FGFR1 in disease R-HSA-5655302 8.510318e-02 1.070 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 7.597035e-02 1.119 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 7.597035e-02 1.119 0 0
VLDL assembly R-HSA-8866423 8.505404e-02 1.070 0 0
CHL1 interactions R-HSA-447041 9.404898e-02 1.027 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 1.117761e-01 0.952 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.205099e-01 0.919 0 0
Attenuation phase R-HSA-3371568 7.928294e-02 1.101 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 9.037208e-02 1.044 0 0
Negative regulation of MAPK pathway R-HSA-5675221 8.510318e-02 1.070 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 9.711193e-02 1.013 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 9.404898e-02 1.027 0 0
Azathioprine ADME R-HSA-9748787 1.127427e-01 0.948 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 8.217697e-02 1.085 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 1.029560e-01 0.987 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 6.717127e-02 1.173 0 0
ESR-mediated signaling R-HSA-8939211 1.122883e-01 0.950 1 0
Signaling by Leptin R-HSA-2586552 1.205099e-01 0.919 0 0
Somitogenesis R-HSA-9824272 9.711193e-02 1.013 0 0
Interleukin-2 family signaling R-HSA-451927 7.928294e-02 1.101 0 0
Interleukin-23 signaling R-HSA-9020933 1.029560e-01 0.987 0 0
Gene Silencing by RNA R-HSA-211000 1.144821e-01 0.941 0 0
Signaling by ALK R-HSA-201556 7.642199e-02 1.117 0 0
Death Receptor Signaling R-HSA-73887 9.189046e-02 1.037 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.104853e-02 1.041 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.064135e-01 0.973 0 0
Hedgehog 'off' state R-HSA-5610787 9.815129e-02 1.008 0 0
Macroautophagy R-HSA-1632852 7.246236e-02 1.140 0 0
Gene expression (Transcription) R-HSA-74160 8.300321e-02 1.081 0 0
ER to Golgi Anterograde Transport R-HSA-199977 8.188892e-02 1.087 0 0
Signaling by Hedgehog R-HSA-5358351 6.860279e-02 1.164 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 9.406590e-02 1.027 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 7.642199e-02 1.117 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.224129e-01 0.912 0 0
FCERI mediated MAPK activation R-HSA-2871796 1.251766e-01 0.902 0 0
Inositol phosphate metabolism R-HSA-1483249 1.251766e-01 0.902 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.291585e-01 0.889 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.291585e-01 0.889 0 0
Chylomicron assembly R-HSA-8963888 1.291585e-01 0.889 0 0
Bicarbonate transporters R-HSA-425381 1.291585e-01 0.889 0 0
Dissolution of Fibrin Clot R-HSA-75205 1.291585e-01 0.889 0 0
HCMV Infection R-HSA-9609646 1.304094e-01 0.885 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.322768e-01 0.879 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 1.322768e-01 0.879 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.356045e-01 0.868 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.356045e-01 0.868 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.377224e-01 0.861 0 0
Activation of RAC1 R-HSA-428540 1.377224e-01 0.861 0 0
Sodium/Calcium exchangers R-HSA-425561 1.377224e-01 0.861 0 0
Metabolism of RNA R-HSA-8953854 1.413759e-01 0.850 0 0
Generic Transcription Pathway R-HSA-212436 1.450332e-01 0.839 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.456968e-01 0.837 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.462027e-01 0.835 0 0
Scavenging by Class F Receptors R-HSA-3000484 1.462027e-01 0.835 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 1.462027e-01 0.835 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.462027e-01 0.835 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 1.462027e-01 0.835 0 0
Regulation of IFNG signaling R-HSA-877312 1.462027e-01 0.835 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.462027e-01 0.835 0 0
Pervasive developmental disorders R-HSA-9005895 1.462027e-01 0.835 0 0
Disorders of Nervous System Development R-HSA-9697154 1.462027e-01 0.835 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 1.462027e-01 0.835 0 0
Interleukin-15 signaling R-HSA-8983432 1.462027e-01 0.835 0 0
Cellular responses to stress R-HSA-2262752 1.478952e-01 0.830 0 0
Formation of paraxial mesoderm R-HSA-9793380 1.490951e-01 0.827 0 0
Signaling by PDGF R-HSA-186797 1.525094e-01 0.817 0 0
NCAM signaling for neurite out-growth R-HSA-375165 1.525094e-01 0.817 1 1
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.546002e-01 0.811 0 0
Frs2-mediated activation R-HSA-170968 1.546002e-01 0.811 0 0
Diseases of nucleotide metabolism R-HSA-9735804 1.546002e-01 0.811 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.546002e-01 0.811 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.546002e-01 0.811 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.546002e-01 0.811 0 0
Host Interactions of HIV factors R-HSA-162909 1.568837e-01 0.804 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.570899e-01 0.804 0 0
CD22 mediated BCR regulation R-HSA-5690714 1.593836e-01 0.798 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 1.629155e-01 0.788 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 1.629155e-01 0.788 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.629155e-01 0.788 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.629155e-01 0.788 0 0
Regulation of KIT signaling R-HSA-1433559 1.629155e-01 0.788 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 1.639793e-01 0.785 0 0
Erythropoietin activates RAS R-HSA-9027284 1.711496e-01 0.767 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.711496e-01 0.767 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 1.711496e-01 0.767 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.711496e-01 0.767 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.711496e-01 0.767 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 1.711496e-01 0.767 0 0
Other semaphorin interactions R-HSA-416700 1.711496e-01 0.767 0 0
Protein methylation R-HSA-8876725 1.711496e-01 0.767 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.732967e-01 0.761 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.732967e-01 0.761 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 1.760358e-01 0.754 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.768059e-01 0.753 0 0
Negative regulation of FLT3 R-HSA-9706369 1.793031e-01 0.746 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.793031e-01 0.746 1 1
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 1.793031e-01 0.746 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 1.793031e-01 0.746 0 0
Killing mechanisms R-HSA-9664420 1.793031e-01 0.746 0 0
Prolonged ERK activation events R-HSA-169893 1.793031e-01 0.746 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.793031e-01 0.746 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.838574e-01 0.736 0 0
Metabolism of cofactors R-HSA-8978934 1.838574e-01 0.736 0 0
Fibronectin matrix formation R-HSA-1566977 1.873770e-01 0.727 0 0
Disorders of Developmental Biology R-HSA-9675151 1.873770e-01 0.727 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.873986e-01 0.727 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.873986e-01 0.727 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 1.873986e-01 0.727 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.909493e-01 0.719 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 1.932547e-01 0.714 0 0
Signaling by FGFR in disease R-HSA-1226099 1.945091e-01 0.711 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.953719e-01 0.709 1 1
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 1.953719e-01 0.709 0 0
Uptake and function of anthrax toxins R-HSA-5210891 1.953719e-01 0.709 0 0
UCH proteinases R-HSA-5689603 2.016539e-01 0.695 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.032887e-01 0.692 0 0
PKA activation R-HSA-163615 2.032887e-01 0.692 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.032887e-01 0.692 0 0
Platelet sensitization by LDL R-HSA-432142 2.032887e-01 0.692 0 0
Nuclear Receptor transcription pathway R-HSA-383280 2.088288e-01 0.680 0 0
G alpha (12/13) signalling events R-HSA-416482 2.088288e-01 0.680 0 0
PCP/CE pathway R-HSA-4086400 2.088288e-01 0.680 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.111280e-01 0.675 0 0
The NLRP3 inflammasome R-HSA-844456 2.111280e-01 0.675 0 0
Other interleukin signaling R-HSA-449836 2.111280e-01 0.675 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 2.111280e-01 0.675 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 2.111280e-01 0.675 0 0
Sensory processing of sound R-HSA-9659379 2.124263e-01 0.673 0 0
Signaling by FGFR2 R-HSA-5654738 2.160299e-01 0.665 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 2.188907e-01 0.660 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.188907e-01 0.660 0 0
Nephrin family interactions R-HSA-373753 2.188907e-01 0.660 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 2.265775e-01 0.645 0 0
Basigin interactions R-HSA-210991 2.265775e-01 0.645 0 0
HIV Infection R-HSA-162906 2.285149e-01 0.641 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.341891e-01 0.630 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.341891e-01 0.630 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.341891e-01 0.630 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.341891e-01 0.630 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.341891e-01 0.630 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.341891e-01 0.630 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.377542e-01 0.624 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.377542e-01 0.624 0 0
FGFR2 alternative splicing R-HSA-6803529 2.417263e-01 0.617 0 0
mTORC1-mediated signalling R-HSA-166208 2.417263e-01 0.617 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.445198e-01 0.612 0 0
Metabolism of nucleotides R-HSA-15869 2.475452e-01 0.606 0 0
RNA Polymerase II Transcription R-HSA-73857 2.486178e-01 0.604 0 0
Diseases of programmed cell death R-HSA-9645723 2.486628e-01 0.604 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 2.491897e-01 0.603 0 0
Formation of the ureteric bud R-HSA-9830674 2.491897e-01 0.603 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.491897e-01 0.603 1 1
Transmission across Chemical Synapses R-HSA-112315 2.521224e-01 0.598 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 2.524035e-01 0.598 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.565802e-01 0.591 0 0
Plasma lipoprotein assembly R-HSA-8963898 2.565802e-01 0.591 0 0
Mitochondrial RNA degradation R-HSA-9836573 2.565802e-01 0.591 0 0
Long-term potentiation R-HSA-9620244 2.638983e-01 0.579 0 0
Laminin interactions R-HSA-3000157 2.638983e-01 0.579 0 0
Tight junction interactions R-HSA-420029 2.638983e-01 0.579 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 2.638983e-01 0.579 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 2.638983e-01 0.579 0 0
Interleukin-7 signaling R-HSA-1266695 2.638983e-01 0.579 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.711449e-01 0.567 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.778056e-01 0.556 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 2.783206e-01 0.555 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 2.783206e-01 0.555 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 2.783206e-01 0.555 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 2.783206e-01 0.555 0 0
Signaling by FGFR3 in disease R-HSA-5655332 2.783206e-01 0.555 0 0
Insulin processing R-HSA-264876 2.783206e-01 0.555 0 0
HIV elongation arrest and recovery R-HSA-167287 2.854260e-01 0.545 0 0
Pausing and recovery of HIV elongation R-HSA-167290 2.854260e-01 0.545 0 0
Insulin receptor recycling R-HSA-77387 2.854260e-01 0.545 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 2.854260e-01 0.545 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 2.854260e-01 0.545 0 0
Inflammasomes R-HSA-622312 2.854260e-01 0.545 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.887263e-01 0.540 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 2.909391e-01 0.536 0 0
Post-translational protein phosphorylation R-HSA-8957275 2.923629e-01 0.534 0 0
Signaling by FGFR R-HSA-190236 2.923629e-01 0.534 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 2.924620e-01 0.534 0 0
DARPP-32 events R-HSA-180024 2.924620e-01 0.534 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 2.924620e-01 0.534 0 0
Platelet calcium homeostasis R-HSA-418360 2.924620e-01 0.534 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 2.924620e-01 0.534 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 2.949722e-01 0.530 0 0
Leishmania parasite growth and survival R-HSA-9664433 2.949722e-01 0.530 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.994291e-01 0.524 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.994291e-01 0.524 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 2.994291e-01 0.524 0 0
Mitotic Spindle Checkpoint R-HSA-69618 2.996289e-01 0.523 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.063280e-01 0.514 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.063280e-01 0.514 0 0
Molecules associated with elastic fibres R-HSA-2129379 3.063280e-01 0.514 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 3.063280e-01 0.514 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.063280e-01 0.514 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 3.068831e-01 0.513 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.068831e-01 0.513 0 0
Influenza Infection R-HSA-168255 3.110771e-01 0.507 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 3.131594e-01 0.504 1 1
RSV-host interactions R-HSA-9833110 3.177373e-01 0.498 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.199239e-01 0.495 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.199239e-01 0.495 0 0
Integrin signaling R-HSA-354192 3.199239e-01 0.495 1 1
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.199239e-01 0.495 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.199239e-01 0.495 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.199239e-01 0.495 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.199239e-01 0.495 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.199239e-01 0.495 0 0
Regulation of necroptotic cell death R-HSA-5675482 3.199239e-01 0.495 0 0
G-protein beta:gamma signalling R-HSA-397795 3.199239e-01 0.495 0 0
Platelet homeostasis R-HSA-418346 3.249523e-01 0.488 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.266223e-01 0.486 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.266223e-01 0.486 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.266223e-01 0.486 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.280817e-01 0.484 1 0
Nuclear import of Rev protein R-HSA-180746 3.332550e-01 0.477 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.398229e-01 0.469 0 0
Signalling to ERKs R-HSA-187687 3.398229e-01 0.469 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 3.398229e-01 0.469 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 3.398229e-01 0.469 0 0
CaM pathway R-HSA-111997 3.463264e-01 0.461 0 0
Calmodulin induced events R-HSA-111933 3.463264e-01 0.461 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 3.527663e-01 0.453 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.527663e-01 0.453 0 0
Ovarian tumor domain proteases R-HSA-5689896 3.527663e-01 0.453 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 3.571515e-01 0.447 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.591431e-01 0.445 0 0
Elastic fibre formation R-HSA-1566948 3.591431e-01 0.445 0 0
Purine salvage R-HSA-74217 3.591431e-01 0.445 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 3.591431e-01 0.445 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 3.591431e-01 0.445 0 0
Interferon alpha/beta signaling R-HSA-909733 3.642363e-01 0.439 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 3.642363e-01 0.439 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.654575e-01 0.437 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.654575e-01 0.437 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.654575e-01 0.437 0 0
RAS processing R-HSA-9648002 3.654575e-01 0.437 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.654575e-01 0.437 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.654575e-01 0.437 0 0
Co-inhibition by PD-1 R-HSA-389948 3.674818e-01 0.435 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.717101e-01 0.430 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.717101e-01 0.430 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.717101e-01 0.430 0 0
HIV Transcription Elongation R-HSA-167169 3.717101e-01 0.430 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.717101e-01 0.430 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.717101e-01 0.430 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 3.717101e-01 0.430 0 0
Glycogen metabolism R-HSA-8982491 3.717101e-01 0.430 0 0
Infection with Enterobacteria R-HSA-9640148 3.754990e-01 0.425 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 3.779014e-01 0.423 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.779014e-01 0.423 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 3.779014e-01 0.423 0 0
Mitotic Prophase R-HSA-68875 3.818164e-01 0.418 0 0
Intra-Golgi traffic R-HSA-6811438 3.840321e-01 0.416 0 0
Signaling by WNT R-HSA-195721 3.843870e-01 0.415 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 3.853083e-01 0.414 0 0
Ca-dependent events R-HSA-111996 3.901028e-01 0.409 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 3.901028e-01 0.409 0 0
MTOR signalling R-HSA-165159 3.901028e-01 0.409 0 0
Signaling by FGFR4 R-HSA-5654743 3.961140e-01 0.402 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 3.961140e-01 0.402 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 4.079604e-01 0.389 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 4.079604e-01 0.389 1 0
Signaling by FGFR3 R-HSA-5654741 4.079604e-01 0.389 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.137967e-01 0.383 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 4.137967e-01 0.383 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 4.137967e-01 0.383 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 4.137967e-01 0.383 0 0
Regulation of pyruvate metabolism R-HSA-9861718 4.137967e-01 0.383 0 0
Apoptotic execution phase R-HSA-75153 4.137967e-01 0.383 1 0
Drug ADME R-HSA-9748784 4.178587e-01 0.379 0 0
Co-stimulation by CD28 R-HSA-389356 4.252983e-01 0.371 0 0
GPER1 signaling R-HSA-9634597 4.252983e-01 0.371 0 0
Metal ion SLC transporters R-HSA-425410 4.252983e-01 0.371 0 0
Plasma lipoprotein remodeling R-HSA-8963899 4.252983e-01 0.371 0 0
Degradation of CDH1 R-HSA-9766229 4.309647e-01 0.366 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.365756e-01 0.360 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 4.387034e-01 0.358 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.421316e-01 0.354 0 0
The phototransduction cascade R-HSA-2514856 4.421316e-01 0.354 0 0
Estrogen-dependent gene expression R-HSA-9018519 4.465662e-01 0.350 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 4.476330e-01 0.349 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.476330e-01 0.349 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.530806e-01 0.344 0 0
Nucleotide biosynthesis R-HSA-8956320 4.530806e-01 0.344 0 0
Cell surface interactions at the vascular wall R-HSA-202733 4.668955e-01 0.331 0 0
NRAGE signals death through JNK R-HSA-193648 4.691050e-01 0.329 0 0
Ion homeostasis R-HSA-5578775 4.691050e-01 0.329 0 0
Signaling by FGFR1 R-HSA-5654736 4.691050e-01 0.329 0 0
Signaling by EGFR R-HSA-177929 4.691050e-01 0.329 0 0
Late Phase of HIV Life Cycle R-HSA-162599 4.694709e-01 0.328 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.726973e-01 0.325 0 0
Signaling by NOTCH R-HSA-157118 4.744784e-01 0.324 0 0
snRNP Assembly R-HSA-191859 4.846628e-01 0.315 0 0
Metabolism of non-coding RNA R-HSA-194441 4.846628e-01 0.315 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 4.846628e-01 0.315 0 0
Regulation of PTEN gene transcription R-HSA-8943724 4.897474e-01 0.310 0 0
Gastrulation R-HSA-9758941 4.918064e-01 0.308 0 0
PLC beta mediated events R-HSA-112043 4.947821e-01 0.306 0 0
Viral Messenger RNA Synthesis R-HSA-168325 4.947821e-01 0.306 0 0
Nucleotide salvage R-HSA-8956321 4.947821e-01 0.306 0 0
MITF-M-dependent gene expression R-HSA-9856651 4.949491e-01 0.305 0 0
Mitochondrial protein import R-HSA-1268020 4.997675e-01 0.301 0 0
tRNA processing in the nucleus R-HSA-6784531 4.997675e-01 0.301 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 4.997675e-01 0.301 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 5.011978e-01 0.300 0 0
Interleukin-1 family signaling R-HSA-446652 5.011978e-01 0.300 0 0
Protein localization R-HSA-9609507 5.043036e-01 0.297 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.095920e-01 0.293 0 0
Ion transport by P-type ATPases R-HSA-936837 5.095920e-01 0.293 0 0
Deubiquitination R-HSA-5688426 5.116273e-01 0.291 0 0
HIV Life Cycle R-HSA-162587 5.166021e-01 0.287 0 0
G-protein mediated events R-HSA-112040 5.239704e-01 0.281 0 0
DNA Double Strand Break Response R-HSA-5693606 5.239704e-01 0.281 0 0
Kidney development R-HSA-9830369 5.239704e-01 0.281 0 0
Signaling by TGFB family members R-HSA-9006936 5.256935e-01 0.279 0 0
Transcription of the HIV genome R-HSA-167172 5.286694e-01 0.277 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 5.286694e-01 0.277 0 0
Regulated Necrosis R-HSA-5218859 5.286694e-01 0.277 0 0
Neuronal System R-HSA-112316 5.312066e-01 0.275 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.379298e-01 0.269 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 5.424919e-01 0.266 0 0
ECM proteoglycans R-HSA-3000178 5.424919e-01 0.266 0 0
Cellular response to chemical stress R-HSA-9711123 5.426888e-01 0.265 0 0
SLC transporter disorders R-HSA-5619102 5.464581e-01 0.262 0 0
Purine catabolism R-HSA-74259 5.470093e-01 0.262 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 5.514823e-01 0.258 0 0
Ca2+ pathway R-HSA-4086398 5.514823e-01 0.258 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.559115e-01 0.255 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 5.646398e-01 0.248 0 0
Integrin cell surface interactions R-HSA-216083 5.731976e-01 0.242 0 0
RNA Polymerase I Transcription R-HSA-73864 5.731976e-01 0.242 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 5.731976e-01 0.242 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 5.815883e-01 0.235 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.815883e-01 0.235 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 5.857219e-01 0.232 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 5.898150e-01 0.229 0 0
Cytoprotection by HMOX1 R-HSA-9707564 5.938678e-01 0.226 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 5.978809e-01 0.223 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 6.018546e-01 0.221 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 6.057893e-01 0.218 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 6.057893e-01 0.218 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.096853e-01 0.215 0 0
Pyruvate metabolism R-HSA-70268 6.135430e-01 0.212 0 0
Downstream TCR signaling R-HSA-202424 6.248904e-01 0.204 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 6.285988e-01 0.202 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 6.359066e-01 0.197 0 0
Asparagine N-linked glycosylation R-HSA-446203 6.393999e-01 0.194 0 0
FCGR activation R-HSA-2029481 6.395067e-01 0.194 0 0
Mitochondrial protein degradation R-HSA-9837999 6.430715e-01 0.192 0 0
Collagen formation R-HSA-1474290 6.430715e-01 0.192 0 0
Signaling by ROBO receptors R-HSA-376176 6.455040e-01 0.190 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 6.466012e-01 0.189 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 6.466012e-01 0.189 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 6.535570e-01 0.185 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 6.535570e-01 0.185 0 0
Epigenetic regulation of gene expression R-HSA-212165 6.605948e-01 0.180 0 0
HATs acetylate histones R-HSA-3214847 6.637363e-01 0.178 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 6.736184e-01 0.172 0 0
PI Metabolism R-HSA-1483255 6.736184e-01 0.172 0 0
Opioid Signalling R-HSA-111885 6.800456e-01 0.167 0 0
Nucleotide Excision Repair R-HSA-5696398 6.863470e-01 0.163 0 0
Stimuli-sensing channels R-HSA-2672351 6.955685e-01 0.158 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 7.064911e-01 0.151 0 0
Rab regulation of trafficking R-HSA-9007101 7.271344e-01 0.138 0 0
Peptide hormone metabolism R-HSA-2980736 7.271344e-01 0.138 0 0
Mitochondrial biogenesis R-HSA-1592230 7.271344e-01 0.138 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.421338e-01 0.130 0 0
Chromatin organization R-HSA-4839726 7.458584e-01 0.127 0 0
Nucleotide catabolism R-HSA-8956319 7.602701e-01 0.119 0 0
Cardiac conduction R-HSA-5576891 7.673300e-01 0.115 0 0
Ribosome-associated quality control R-HSA-9948299 7.851625e-01 0.105 0 0
PTEN Regulation R-HSA-6807070 7.872939e-01 0.104 0 0
Visual phototransduction R-HSA-2187338 8.055546e-01 0.094 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 8.112884e-01 0.091 0 0
DNA Double-Strand Break Repair R-HSA-5693532 8.168541e-01 0.088 0 0
HCMV Late Events R-HSA-9610379 8.240221e-01 0.084 0 0
Interferon gamma signaling R-HSA-877300 8.275008e-01 0.082 0 0
Regulation of TP53 Activity R-HSA-5633007 8.292145e-01 0.081 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 8.469839e-01 0.072 0 0
tRNA processing R-HSA-72306 8.469839e-01 0.072 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 8.485051e-01 0.071 0 0
G alpha (s) signalling events R-HSA-418555 8.485051e-01 0.071 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 8.500114e-01 0.071 0 0
Cellular Senescence R-HSA-2559583 8.615375e-01 0.065 0 0
TCF dependent signaling in response to WNT R-HSA-201681 8.656290e-01 0.063 0 0
Peptide ligand-binding receptors R-HSA-375276 8.696004e-01 0.061 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 8.721830e-01 0.059 0 0
Ion channel transport R-HSA-983712 8.734551e-01 0.059 0 0
DNA Repair R-HSA-73894 8.913461e-01 0.050 0 0
Metabolism of vitamins and cofactors R-HSA-196854 8.947611e-01 0.048 0 0
GPCR downstream signalling R-HSA-388396 8.973612e-01 0.047 0 0
Post-translational protein modification R-HSA-597592 9.118239e-01 0.040 0 0
rRNA processing R-HSA-72312 9.185615e-01 0.037 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.200228e-01 0.036 0 0
Chromatin modifying enzymes R-HSA-3247509 9.201791e-01 0.036 0 0
G alpha (i) signalling events R-HSA-418594 9.262982e-01 0.033 0 0
Signaling by GPCR R-HSA-372790 9.379626e-01 0.028 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.486967e-01 0.023 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.507204e-01 0.022 0 0
Phospholipid metabolism R-HSA-1483257 9.567654e-01 0.019 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.728140e-01 0.012 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.824019e-01 0.008 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.842578e-01 0.007 0 0
Fatty acid metabolism R-HSA-8978868 9.862019e-01 0.006 0 0
Diseases of metabolism R-HSA-5668914 9.887369e-01 0.005 0 0
Translation R-HSA-72766 9.889634e-01 0.005 0 0
Metabolism of proteins R-HSA-392499 9.932723e-01 0.003 0 0
Biological oxidations R-HSA-211859 9.957645e-01 0.002 0 0
Transport of small molecules R-HSA-382551 9.975518e-01 0.001 0 0
GPCR ligand binding R-HSA-500792 9.978454e-01 0.001 0 0
Sensory Perception R-HSA-9709957 9.997471e-01 0.000 0 0
Metabolism R-HSA-1430728 9.997944e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.999972e-01 0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways