PLK1

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA

Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included

S Sites Probabilities

T Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Sites with acceptor types representing >8% and count ≥10 are included

Download Data Table

Motif clusters with count ≥ 10 are shown

Download

substrate_uniprot	site	source	substrate_genes	site_seq
A5A3E0	S1065	Sugiyama	POTEF A26C1B	ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________
A5A3E0	S1068	Sugiyama	POTEF A26C1B	SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0	S939	Sugiyama	POTEF A26C1B	VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A6NMY6	S164	Sugiyama	ANXA2P2 ANX2L2 ANX2P2 LPC2B	NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGS
O00115	S57	Sugiyama	DNASE2 DNASE2A DNL2	ALRGSGEAAQRGLQYKyLDEssGGWRDGRALINsPEGAVGR
O00139	T554	EPSD\|PSP	KIF2A KIF2 KNS2	MASCENTLNTLRYANRVKELtVDPTAAGDVRPIMHHPPNQI
O00410	S827	Sugiyama	IPO5 KPNB3 RANBP5	NQELRQVKRQDEDyDEQVEEsLQDEDDNDVyILTKVSDILH
O00505	S60	Sugiyama	KPNA3 QIP2	KRDEHLLKKRNVPQEEsLEDsDVDADFKAQNVTLEAILQNA
O14641	T206	SIGNOR\|EPSD\|PSP	DVL2	ERHLAGYESSSTLMTSELEStSLGDsDEEDTMSRFSSStEQ
O14920	S733	GPS6\|SIGNOR\|EPSD\|PSP	IKBKB IKKB	HNLCTLLENAIQDTVREQDQsFTALDWsWLQTEEEEHsCLE
O14920	S740	GPS6\|SIGNOR\|EPSD\|PSP	IKBKB IKKB	ENAIQDTVREQDQsFTALDWsWLQTEEEEHsCLEQAs____
O14920	S750	GPS6\|SIGNOR\|EPSD\|PSP	IKBKB IKKB	QDQsFTALDWsWLQTEEEEHsCLEQAs______________
O14980	T1030	Sugiyama	XPO1 CRM1	AFKEHLRDFLVQIKEFAGEDtsDLFLEEREIALRQADEEKH
O14981	S261	Sugiyama	BTAF1 TAF172	EPEEKRRKIANVVINQsANDsKVLIDNIPDSSSLIEETNEW
O15350	T27	GPS6\|SIGNOR\|EPSD\|PSP	TP73 P73	TSPDGGTTFEHLWSSLEPDStyFDLPQSSRGNNEVVGGTDs
O15355	S349	Sugiyama	PPM1G PPM1C	tTAVVALIRGKQLIVANAGDsRCVVsEAGKALDMsyDHKPE
O15392	S20	SIGNOR\|EPSD\|PSP	BIRC5 API4 IAP4	_MGAPTLPPAWQPFLKDHRIstFKNWPFLEGCACtPERMAE
O15392	T21	EPSD\|PSP	BIRC5 API4 IAP4	MGAPTLPPAWQPFLKDHRIstFKNWPFLEGCACtPERMAEA
O43379	S897	EPSD\|PSP	WDR62 C19orf14	LDAQDLDCYFTPMKPESLENsILDSLEPQSLASLLSESESP
O43390	T134	Sugiyama	HNRNPR HNRPR	KVQESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O43390	Y136	Sugiyama	HNRNPR HNRPR	QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O43399	S21	Sugiyama	TPD52L2	MDsAGQDINLNsPNKGLLsDsMtDVPVDTGVAARtPAVEGL
O43474	S234	SIGNOR\|PSP	KLF4 EZF GKLF	PPQQPQPPGGGLMGKFVLKAsLsAPGsEYGsPsVIsVsKGs
O43615	S193	Sugiyama	TIMM44 MIMT44 TIM44	TAAFRALsQGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEF
O43663	S615	EPSD\|PSP	PRC1	GLQRELsKASKSDATsGILNstNIQs_______________
O43663	T616	GPS6\|EPSD\|PSP	PRC1	LQRELsKASKSDATsGILNstNIQs________________
O43719	S713	Sugiyama	HTATSF1	DEKLFEDDDsNEKLFDEEEDssEKLFDDsDERGTLGGFGSV
O43852	S44	Sugiyama	CALU	KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL
O43852	S69	Sugiyama	CALU	HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt
O43852	T196	Sugiyama	CALU	FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD
O43852	T89	Sugiyama	CALU	sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60216	S175	PSP	RAD21 HR21 KIAA0078 NXP1 SCC1	LQENDFGDFGMDDREIMREGsAFEDDDMLVstttsNLLLES
O60216	S454	PSP	RAD21 HR21 KIAA0078 NXP1 SCC1	HQQRDVIDEPIIEEPsRLQEsVMEAsRTNIDESAMPPPPPQ
O60220	S94	Sugiyama	TIMM8A DDP DDP1 TIM8A	SQFILNRLEQTQKSKPVFSEsLsD_________________
O60260	S378	SIGNOR\|EPSD\|PSP	PRKN PARK2	LGCGFAFCRECKEAYHEGECsAVFEASGTTTQAYRVDERAA
O60285	S476	EPSD\|PSP	NUAK1 ARK5 KIAA0537 OMPHK1	PKQSATMPKKGILKKTQQREsGYYssPERsESsELLDSNDV
O60285	S480	EPSD\|PSP	NUAK1 ARK5 KIAA0537 OMPHK1	ATMPKKGILKKTQQREsGYYssPERsESsELLDSNDVMGSS
O60341	S126	EPSD\|PSP	KDM1A AOF2 KDM1 KIAA0601 LSD1	EGRRTsRRKRAKVEyREMDEsLANLsEDEyysEEERNAKAE
O60343	S304	Sugiyama	TBC1D4 AS160 KIAA0603	ASQPALTSSRVCFPERILEDsGFDEQQEFRsRCssVTGVQR
O60506	T131	Sugiyama	SYNCRIP HNRPQ NSAP1	KVADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O60506	Y133	Sugiyama	SYNCRIP HNRPQ NSAP1	ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O60563	S564	SIGNOR\|EPSD\|PSP	CCNT1	DPKHSSQTSNLAHKTYSLSssFsSSsSTRKRGPsEEtGGAV
O60566	S676	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	BUB1B BUBR1 MAD3L SSK1	CGtIysQtLsIKKLsPIIEDsREAtHSsGFsGSSAsVAstS
O60566	T1008	GPS6\|SIGNOR\|EPSD\|PSP	BUB1B BUBR1 MAD3L SSK1	KDGELWNKFFVRILNANDEAtVSVLGELAAEMNGVFDTTFQ
O60566	T680	SIGNOR\|EPSD\|PSP	BUB1B BUBR1 MAD3L SSK1	ysQtLsIKKLsPIIEDsREAtHSsGFsGSSAsVAstSsIKC
O60566	T792	GPS6\|SIGNOR\|EPSD\|PSP	BUB1B BUBR1 MAD3L SSK1	YLICEDYKLFWVAPRNSAELtVIKVSSQPVPWDFYINLKLK
O60610	S542	Sugiyama	DIAPH1 DIAP1	ALHSEKQQIATEKQDLEAEVsQLtGEVAKLTKELEDAKKEM
O60716	S920	Sugiyama	CTNND1 KIAA0384	LDNNystPNERGDHNRtLDRsGDLGDMEPLKGttPLMQDEG
O60716	T916	Sugiyama	CTNND1 KIAA0384	NtKsLDNNystPNERGDHNRtLDRsGDLGDMEPLKGttPLM
O60749	S302	Sugiyama	SNX2 TRG9	LRMVNKAADAVNKMTIKMNEsDAWFEEKQQQFENLDQQLRK
O60841	S182	Sugiyama	EIF5B IF2 KIAA0741	DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK
O60841	S66	Sugiyama	EIF5B IF2 KIAA0741	KEKKKQDFDEDDILKELEELsLEAQGIKADREtVAVKPTEN
O75116	T567	Sugiyama	ROCK2 KIAA0619	NQNSQISTEKVNQLQRQLDEtNALLRtESDTAARLRKTQAE
O75122	S1027	PSP	CLASP2 KIAA0627	sMPtHssPRsRDyNPyNysDsIsPFNKsALKEAMFDDDADQ
O75122	S1034	PSP	CLASP2 KIAA0627	PRsRDyNPyNysDsIsPFNKsALKEAMFDDDADQFPDDLsL
O75122	S1053	PSP	CLASP2 KIAA0627	KsALKEAMFDDDADQFPDDLsLDHsDLVAELLKELSNHNER
O75122	S1092	PSP	CLASP2 KIAA0627	ERVEERKIALYELMKLTQEEsFSVWDEHFKTILLLLLETLG
O75170	S289	EPSD\|PSP	PPP6R2 KIAA0685 PP6R2 SAPS2	TQVLLTLLETRRVGtEGLVDsFsQGLERSYAVSSSVLHGIE
O75170	T10	EPSD\|PSP	PPP6R2 KIAA0685 PP6R2 SAPS2	___________MFWKFDLNTtSHVDKLLDKEHVTLQELMDE
O75534	T761	Sugiyama	CSDE1 D1S155E KIAA0885 NRU UNR	GPKAVAAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDN
O75821	S189	Sugiyama	EIF3G EIF3S4	CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK
O75821	T27	Sugiyama	EIF3G EIF3S4	DsKPsWADQVEEEGEDDKCVtsELLKGIPLAtGDtsPEPEL
O75822	S127	Sugiyama	EIF3J EIF3S1 PRO0391	VLtPEEQLADKLRLKKLQEEsDLELAKEtFGVNNAVyGIDA
O76094	S616	Sugiyama	SRP72	DQIGKGtQGAtAGAssELDAsKtVssPPtsPRPGsAAtVsA
O94901	S138	SIGNOR\|PSP	SUN1 KIAA0810 UNC84A	HGGTVSLQDAVTRRPPVLDEsWIREQTTVDHFWGLDDDGDL
O95218	S165	Sugiyama	ZRANB2 ZIS ZNF265	LKEVEDKEsEGEEEDEDEDLsKyKLDEDEDEDDADLsKyNL
O95218	S181	Sugiyama	ZRANB2 ZIS ZNF265	DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95218	S188	Sugiyama	ZRANB2 ZIS ZNF265	KLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRRSRSKSRS
O95235	S528	GPS6\|EPSD	KIF20A MKLP2 RAB6KIFL	VHAPPMQLGFPSLHSFIKEHsLQVsPsLEKGAKADTGLDDD
O95251	S57	SIGNOR\|EPSD\|PSP	KAT7 HBO1 HBOa MYST2	RRSARVTRssARLsQssQDssPVRNLQsFGTEEPAYstRRV
O95271	S978	SIGNOR\|PSP	TNKS PARP5A PARPL TIN1 TINF1 TNKS1	PEALPTCFKPQATVVSASLIsPAStPSCLsAASsIDNLTGP
O95271	T1128	SIGNOR\|PSP	TNKS PARP5A PARPL TIN1 TINF1 TNKS1	LLDLAPEDKEYQSVEEEMQStIREHRDGGNAGGIFNRYNVI
O95271	T839	SIGNOR\|PSP	TNKS PARP5A PARPL TIN1 TINF1 TNKS1	VQKLCTPENINCRDTQGRNStPLHLAAGYNNLEVAEYLLEH
O95271	T930	SIGNOR\|PSP	TNKS PARP5A PARPL TIN1 TINF1 TNKS1	AAQKGRTQLCALLLAHGADPtMKNQEGQTPLDLATADDIRA
O95271	T982	SIGNOR\|PSP	TNKS PARP5A PARPL TIN1 TINF1 TNKS1	PTCFKPQATVVSASLIsPAStPSCLsAASsIDNLTGPLAEL
O95425	S238	SIGNOR\|EPSD\|PSP\|Sugiyama	SVIL	HDLsPAAEsssTFsFSGRDssFtEVPRsPKHAHSssLQQAA
O95433	T20	Sugiyama	AHSA1 C14orf3 HSPC322	_MAKWGEGDPRWIVEERADAtNVNNWHWtERDASNWSTDKL
O95613	S1235	EPSD\|PSP	PCNT KIAA0402 PCNT2	LPELDRtLSECAEMSSVAEIsSHMREsFLMsPESVRECEQP
O95613	S1241	EPSD\|PSP	PCNT KIAA0402 PCNT2	tLSECAEMSSVAEIsSHMREsFLMsPESVRECEQPIRRVFQ
O95613	T1209	EPSD\|PSP	PCNT KIAA0402 PCNT2	LCLDDAGAGLALSTAPALEEtWSDVALPELDRtLSECAEMS
O95613	T1221	EPSD\|PSP	PCNT KIAA0402 PCNT2	STAPALEEtWSDVALPELDRtLSECAEMSSVAEIsSHMREs
O95678	S162	Sugiyama	KRT75 K6HF KB18	IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95757	S599	Sugiyama	HSPA4L APG1 HSPH3 OSP94	sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND
O95757	Y600	Sugiyama	HSPA4L APG1 HSPH3 OSP94	IDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERNDA
O96017	S164	EPSD\|PSP	CHEK2 CDS1 CHK2 RAD53	FRIFREVGPKNSyIAYIEDHsGNGTFVNTELVGKGKRRPLN
O96017	S210	EPSD\|PSP	CHEK2 CDS1 CHK2 RAD53	ALSLSRNKVFVFFDLtVDDQsVYPKALRDEYIMSKtLGSGA
O96017	T205	EPSD\|PSP	CHEK2 CDS1 CHK2 RAD53	NNSEIALSLSRNKVFVFFDLtVDDQsVYPKALRDEYIMSKt
O96017	T26	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	CHEK2 CDS1 CHK2 RAD53	DVEAQQSHGSSACsQPHGSVtQsQGSSsQsQGISSSSTSTM
O96017	T68	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CHEK2 CDS1 CHK2 RAD53	NSsQSSHSSSGTLSsLETVStQELYsIPEDQEPEDQEPEEP
P00338	S161	Sugiyama	LDHA PIG19	DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00558	S393	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA
P00558	S399	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558	T394	Sugiyama	PGK1 PGKA MIG10 OK/SW-cl.110	GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL
P01106	S77	PSP	MYC BHLHE39	PPAPSEDIWKKFELLPtPPLsPsRRsGLCsPSyVAVTPFsL
P02538	S176	Sugiyama	KRT6A K6A KRT6D	IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02786	S151	Sugiyama	TFRC	LsEKLDstDFTGtIKLLNENsyVPREAGsQKDENLALyVEN
P04075	S17	Sugiyama	ALDOA ALDA	____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst
P04075	S336	Sugiyama	ALDOA ALDA	GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075	S356	Sugiyama	ALDOA ALDA	sLACQGKytPsGQAGAAAsEsLFVsNHAy____________
P04075	S36	Sugiyama	ALDOA ALDA	LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075	S360	Sugiyama	ALDOA ALDA	QGKytPsGQAGAAAsEsLFVsNHAy________________
P04075	S46	Sugiyama	ALDOA ALDA	PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075	T123	Sugiyama	ALDOA ALDA	GVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGA
P04075	T37	Sugiyama	ALDOA ALDA	sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04083	S173	Sugiyama	ANXA1 ANX1 LPC1	NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG
P04083	S189	Sugiyama	ANXA1 ANX1 LPC1	tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA
P04083	T169	Sugiyama	ANXA1 ANX1 LPC1	IRDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRs
P04259	S176	Sugiyama	KRT6B K6B KRTL1	IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406	S241	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406	S312	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA
P04406	S321	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406	T237	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406	T246	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04406	Y314	Sugiyama	GAPDH GAPD CDABP0047 OK/SW-cl.12	tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P05362	T454	Sugiyama	ICAM1	DGtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTRKVTVNV
P05386	S101	Sugiyama	RPLP1 RRP1	APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386	S104	Sugiyama	RPLP1 RRP1	tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387	S102	Sugiyama	RPLP2 D11S2243E RPP2	PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387	S105	Sugiyama	RPLP2 D11S2243E RPP2	GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05388	S307	Sugiyama	RPLP0	AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
P05455	S325	Sugiyama	SSB	VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05556	S503	Sugiyama	ITGB1 FNRB MDF2 MSK12	TFECGACRCNEGRVGRHCECstDEVNsEDMDAYCRKENSSE
P05787	S104	Sugiyama	KRT8 CYK8	IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787	S291	Sugiyama	KRT8 CYK8	ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P05787	S410	Sugiyama	KRT8 CYK8	TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P05787	S475	Sugiyama	KRT8 CYK8	TSSSRAVVVKKIETRDGKLVsEssDVLPK____________
P06400	S758	PSP	RB1	TFKRVLIKEEEYDSIIVFYNsVFMQRLKtNILQyAstRPPt
P06733	T100	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733	T205	Sugiyama	ENO1 ENO1L1 MBPB1 MPB1	GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06748	S4	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NPM1 NPM	_________________MEDsMDMDMsPLRPQNyLFGCELK
P07195	S162	Sugiyama	LDHB	DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195	S303	Sugiyama	LDHB	GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195	T323	Sugiyama	LDHB	sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205	S393	Sugiyama	PGK2 PGKB	GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA
P07205	S399	Sugiyama	PGK2 PGKB	CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205	T394	Sugiyama	PGK2 PGKB	GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL
P07237	S88	Sugiyama	P4HB ERBA2L PDI PDIA1 PO4DB	GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG
P07237	T428	Sugiyama	P4HB ERBA2L PDI PDIA1 PO4DB	DKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFPA
P07237	T85	Sugiyama	P4HB ERBA2L PDI PDIA1 PO4DB	KAAGKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFF
P07355	S164	Sugiyama	ANXA2 ANX2 ANX2L4 CAL1H LPC2D	NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGs
P07355	S184	Sugiyama	ANXA2 ANX2 ANX2L4 CAL1H LPC2D	sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07355	Y188	Sugiyama	ANXA2 ANX2 ANX2L4 CAL1H LPC2D	RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07737	S30	Sugiyama	PFN1	NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07864	S161	Sugiyama	LDHC LDH3 LDHX	DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900	S399	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK
P07900	S505	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900	S53	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900	S63	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P07900	S68	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	LIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQDRt
P07900	S72	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	ssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQDRtLtIV
P07900	T195	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG
P07900	T305	Sugiyama	HSP90AA1 HSP90A HSPC1 HSPCA	IDQEELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLA
P07942	S448	Sugiyama	LAMB1	CKLNVEGEHCDVCKEGFyDLssEDPFGCKSCACNPLGTIPG
P08238	S391	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK
P08238	S45	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238	S462	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238	S468	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238	S497	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238	S58	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238	S63	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	LIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERt
P08238	S67	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	AsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERtLtLV
P08238	T190	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
P08238	T297	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	IDQEELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLA
P08238	T467	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238	Y457	Sugiyama	HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB	LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08621	S410	Sugiyama	SNRNP70 RNPU1Z RPU1 SNRP70 U1AP1	DEARGGGGGQDNGLEGLGNDsRDMYMESEGGDGYLAPENGY
P08670	S339	PSP	VIM	YRRQVQsLtCEVDALKGtNEsLERQMREMEENFAVEAANyQ
P08670	S459	PSP\|Sugiyama	VIM	KRTLLIKtVEtRDGQVINEtsQHHDDLE_____________
P08670	S56	EPSD\|PSP	VIM	RtYsLGsALRPstsRsLyAssPGGVyAtRssAVRLRssVPG
P08670	S83	SIGNOR\|EPSD\|PSP	VIM	tRssAVRLRssVPGVRLLQDsVDFsLADAINTEFKNTRTNE
P08670	T327	PSP	VIM	DALRQAKQESTEYRRQVQsLtCEVDALKGtNEsLERQMREM
P08670	T336	PSP	VIM	STEYRRQVQsLtCEVDALKGtNEsLERQMREMEENFAVEAA
P08708	S89	Sugiyama	RPS17 RPS17L	ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL
P08729	S104	Sugiyama	KRT7 SCL	LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P08758	S136	Sugiyama	ANXA5 ANX5 ENX2 PP4	sRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYYQRMLVVL
P09661	S212	Sugiyama	SNRPA1	KKGGPsPGDVEAIKNAIANAstLAEVERLKGLLQsGQIPGR
P09960	S486	Sugiyama	LTA4H LTA4	TNACIALSQRWITAKEDDLNsFNAtDLKDLsSHQLNEFLAQ
P09960	T490	Sugiyama	LTA4H LTA4	IALSQRWITAKEDDLNsFNAtDLKDLsSHQLNEFLAQtLQR
P09972	T124	Sugiyama	ALDOC ALDC	VVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGAD
P0CG38	S1065	Sugiyama	POTEI	ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG38	S1068	Sugiyama	POTEI	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39	S1028	Sugiyama	POTEJ	ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG39	S1031	Sugiyama	POTEJ	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DMV8	S631	PSP	HSPA1A HSP72 HSPA1 HSX70	yQGAGGPGPGGFGAQGPKGGsGsGPtIEEVD__________
P0DMV8	S633	PSP	HSPA1A HSP72 HSPA1 HSX70	GAGGPGPGGFGAQGPKGGsGsGPtIEEVD____________
P0DPH7	S48	Sugiyama	TUBA3C TUBA2	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7	T41	Sugiyama	TUBA3C TUBA2	WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P0DPH7	T51	Sugiyama	TUBA3C TUBA2	QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P10412	S55	Sugiyama	H1-4 H1F4 HIST1H1E	AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10809	S488	Sugiyama	HSPD1 HSP60	IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P10809	T105	Sugiyama	HSPD1 HSP60	DLKDKYKNIGAKLVQDVANNtNEEAGDGtttAtVLARSIAK
P11047	S942	Sugiyama	LAMC1 LAMB2	GFYNLQSGQGCERCDCHALGstNGQCDIRTGQCECQPGITG
P11047	T1127	Sugiyama	LAMC1 LAMB2	NNTLSSQISRLQNIRNTIEEtGNLAEQARAHVENTERLIEI
P11142	S40	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142	T226	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142	T37	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P11142	Y41	Sugiyama	HSPA8 HSC70 HSP73 HSPA10	FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11388	S1337	SIGNOR\|EPSD\|PSP	TOP2A TOP2	PRRAATKTKFTMDLDsDEDFsDFDEKtDDEDFVPsDAsPPK
P11388	S1525	SIGNOR\|EPSD\|PSP	TOP2A TOP2	AVAPRAKSVRAKKPIKYLEEsDEDDLF______________
P11388	T1343	EPSD\|PSP	TOP2A TOP2	KTKFTMDLDsDEDFsDFDEKtDDEDFVPsDAsPPKtKTsPK
P11413	T406	SIGNOR	G6PD	KRNELVIRVQPNEAVyTKMMtKKPGMFFNPEESELDLTYGN
P11413	T466	SIGNOR	G6PD	CGSQMHFVRSDELREAWRIFtPLLHQIELEKPKPIPYIYGs
P11586	S129	Sugiyama	MTHFD1 MTHFC MTHFD	INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP
P11586	S323	Sugiyama	MTHFD1 MTHFC MTHFD	WMIQYNNLNLKTPVPsDIDIsRSCKPKPIGKLAREIGLLSE
P11717	S1378	Sugiyama	IGF2R MPRI	QYACPPFDLTECSFKDGAGNsFDLsSLSRYSDNWEAITGTG
P12035	S211	Sugiyama	KRT3	IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12270	S2048	Sugiyama	TPR	NHRAADsQNsGEGNtGAAEssFsQEVsREQQPSsASERQAP
P12270	S2050	Sugiyama	TPR	RAADsQNsGEGNtGAAEssFsQEVsREQQPSsASERQAPRA
P12830	S146	SIGNOR	CDH1 CDHE UVO	PPHQASVSGIQAELLTFPNSsPGLRRQKRDWVIPPISCPEN
P13489	S178	Sugiyama	RNH1 PRI RNH	SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13489	S290	Sugiyama	RNH1 PRI RNH	AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE
P13489	T176	Sugiyama	RNH1 PRI RNH	AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD
P13639	S23	Sugiyama	EEF2 EF2	NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639	S587	Sugiyama	EEF2 EF2	CIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKAR
P13639	T5	Sugiyama	EEF2 EF2	________________MVNFtVDQIRAIMDKKANIRNMsVI
P13647	S181	Sugiyama	KRT5	IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667	S135	Sugiyama	PDIA4 ERP70 ERP72	IPVAKIDAtsAsVLAsRFDVsGyPtIKILKKGQAVDyEGsR
P13667	S470	Sugiyama	PDIA4 ERP70 ERP72	FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP
P13667	S482	Sugiyama	PDIA4 ERP70 ERP72	VKDLGLsEsGEDVNAAILDEsGKKFAMEPEEFDsDtLREFV
P13693	S46	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	TPT1	GLCLEVEGKMVSRTEGNIDDsLIGGNASAEGPEGEGTEstV
P13693	S64	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD	TPT1	DDsLIGGNASAEGPEGEGTEstVITGVDIVMNHHLQETSFT
P13798	S185	Sugiyama	APEH D3F15S2 D3S48E DNF15S2	VAEKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQ
P13861	S99	Sugiyama	PRKAR2A PKR2 PRKAR2	EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13861	Y105	Sugiyama	PRKAR2A PKR2 PRKAR2	DLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVIHPKTDE
P13987	T76	Sugiyama	CD59 MIC11 MIN1 MIN2 MIN3 MSK21	AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF
P14314	S108	Sugiyama	PRKCSH G19P1	PSNRVNDGVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQ
P14314	S126	Sugiyama	PRKCSH G19P1	yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314	T134	Sugiyama	PRKCSH G19P1	NtCKEKGRKEREsLQQMAEVtREGFRLKKILIEDWKKAREE
P14625	S106	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625	S64	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14625	T522	Sugiyama	HSP90B1 GRP94 HSPC4 TRA1	NRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMA
P14635	S126	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CCNB1 CCNB	EPEPVKEEKLsPEPILVDTAsPsPMETsGCAPAEEDLCQAF
P14635	S128	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CCNB1 CCNB	EPVKEEKLsPEPILVDTAsPsPMETsGCAPAEEDLCQAFsD
P14635	S133	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CCNB1 CCNB	EKLsPEPILVDTAsPsPMETsGCAPAEEDLCQAFsDVILAV
P14635	S147	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CCNB1 CCNB	PsPMETsGCAPAEEDLCQAFsDVILAVNDVDAEDGADPNLC
P14854	S52	Sugiyama	COX6B1 COX6B	QNyLDFHRCQKAMTAKGGDIsVCEWyQRVYQsLCPtsWVTD
P15311	S535	Sugiyama	EZR VIL2	EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P15311	T533	Sugiyama	EZR VIL2	NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15374	S126	Sugiyama	UCHL3	NNKDKMHFESGSTLKKFLEEsVsMsPEERARyLENyDAIRV
P15374	S151	Sugiyama	UCHL3	PEERARyLENyDAIRVtHEtsAHEGQTEAPsIDEKVDLHFI
P15531	S120	Sugiyama	NME1 NDPKA NM23	KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P15531	S122	Sugiyama	NME1 NDPKA NM23	GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15924	S1259	Sugiyama	DSP	LDRLSRENRDLKDEIVRLNDsILQATEQRRRAEENALQQKA
P16402	S56	Sugiyama	H1-3 H1F3 HIST1H1D	AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403	S55	Sugiyama	H1-2 H1F2 HIST1H1C	AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P17066	S42	Sugiyama	HSPA6 HSP70B'	VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17066	T228	Sugiyama	HSPA6 HSP70B'	DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17987	S551	Sugiyama	TCP1 CCT1 CCTA	IKLHPESKDDKHGsyEDAVHsGALND_______________
P17987	Y545	Sugiyama	TCP1 CCT1 CCTA	LRIDDLIKLHPESKDDKHGsyEDAVHsGALND_________
P18031	S286	SIGNOR\|EPSD\|PSP	PTPN1 PTP1B	QLRFSYLAVIEGAKFIMGDSsVQDQWKELsHEDLEPPPEHI
P18031	S393	EPSD\|PSP	PTPN1 PTP1B	RVVGGsLRGAQAAsPAKGEPsLPEKDEDHALSYWKPFLVNM
P18615	S135	Sugiyama	NELFE RD RDBP	sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG
P18669	T146	Sugiyama	PGAM1 PGAMA CDABP0006	MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF
P19338	S460	Sugiyama	NCL	ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P20042	T175	Sugiyama	EIF2S2 EIF2B	DGIsFsNQtGPAWAGSERDytyEELLNRVFNIMREKNPDMV
P21333	S1029	Sugiyama	FLNA FLN FLN1	VGPSGAAVPCKVEPGLGADNsVVRFLPREEGPYEVEVTYDG
P22314	S820	Sugiyama	UBA1 A1S9T UBE1	tPKsGVKIHVsDQELQsANAsVDDsRLEELKATLPsPDKLP
P22314	S824	Sugiyama	UBA1 A1S9T UBE1	GVKIHVsDQELQsANAsVDDsRLEELKATLPsPDKLPGFKM
P22314	T233	Sugiyama	UBA1 A1S9T UBE1	GEQPLSAMVSMVTKDNPGVVtCLDEARHGFESGDFVSFSEV
P22692	S255	Sugiyama	IGFBP4 IBP4	VKLPGGLEPKGELDCHQLADsFRE_________________
P23246	S283	Sugiyama	SFPQ PSF	GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23381	S358	Sugiyama	WARS1 IFI53 WARS WRS	TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23526	S183	Sugiyama	AHCY SAHH	NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23528	T63	Sugiyama	CFL1 CFL	DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528	T70	Sugiyama	CFL1 CFL	EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23588	S122	Sugiyama	EIF4B	NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P23588	S207	Sugiyama	EIF4B	DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR
P25490	T39	SIGNOR\|EPSD\|PSP	YY1 INO80S	EIVELHEIEVETIPVETIETtVVGEEEEEDDDDEDGGGGDH
P25705	S53	Sugiyama	ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM	ARNFHASNTHLQKtGtAEMssILEERILGADtsVDLEETGR
P25705	S65	Sugiyama	ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM	KtGtAEMssILEERILGADtsVDLEETGRVLsIGDGIARVH
P25786	S211	Sugiyama	PSMA1 HC2 NU PROS30 PSC2	GLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDDDVsP
P25786	T11	Sugiyama	PSMA1 HC2 NU PROS30 PSC2	__________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ
P26038	S576	Sugiyama	MSN	YKtLRQIRQGNTKQRIDEFEsM___________________
P26373	S181	Sugiyama	RPL13 BBC1 OK/SW-cl.46	YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373	S77	Sugiyama	RPL13 BBC1 OK/SW-cl.46	PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26639	S522	Sugiyama	TARS1 TARS	PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP
P26639	S70	Sugiyama	TARS1 TARS	WPEyIytRLEMYNILKAEHDsILAEKAEKDSKPIKVTLPDG
P27348	S145	Sugiyama	YWHAQ	YFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHP
P27348	S156	Sugiyama	YWHAQ	DDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLGLALNFSV
P27348	S37	Sugiyama	YWHAQ	ERyDDMAtCMKAVtEQGAELsNEERNLLsVAyKNVVGGRRS
P27348	S45	Sugiyama	YWHAQ	CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27797	S214	Sugiyama	CALR CRTC	GsLEDDWDFLPPKKIKDPDAsKPEDWDERAKIDDPtDsKPE
P27797	S52	Sugiyama	CALR CRTC	GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P29692	S44	Sugiyama	EEF1D EF1D	RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P30050	S157	Sugiyama	RPL12	QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P30050	S26	Sugiyama	RPL12	DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI
P30084	S107	Sugiyama	ECHS1	LTGGDKAFAAGADIKEMQNLsFQDCySSKFLKHWDHLTQVK
P30101	T437	Sugiyama	PDIA3 ERP57 ERP60 GRP58	KELGEKLsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsP
P30260	S426	EPSD\|PSP	CDC27 ANAPC3 D0S1430E D17S978E	NRKTKSKTNKGGITQPNINDsLEItKLDssIIsEGKIStIt
P30260	S434	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	CDC27 ANAPC3 D0S1430E D17S978E	NKGGITQPNINDsLEItKLDssIIsEGKIStItPQIQAFNL
P30260	S435	EPSD\|PSP	CDC27 ANAPC3 D0S1430E D17S978E	KGGITQPNINDsLEItKLDssIIsEGKIStItPQIQAFNLQ
P30260	T205	EPSD\|PSP	CDC27 ANAPC3 D0S1430E D17S978E	TTQVPNHsLSHRQPEtVLTEtPQDtIELNRLNLEssNsKYS
P30260	T209	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	CDC27 ANAPC3 D0S1430E D17S978E	PNHsLSHRQPEtVLTEtPQDtIELNRLNLEssNsKYSLNTD
P30260	T430	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	CDC27 ANAPC3 D0S1430E D17S978E	KSKTNKGGITQPNINDsLEItKLDssIIsEGKIStItPQIQ
P30260	T446	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	CDC27 ANAPC3 D0S1430E D17S978E	sLEItKLDssIIsEGKIStItPQIQAFNLQKAAAEGLMSLL
P30291	S123	SIGNOR	WEE1	DEAGGGAEGDSWEEEGFGsSsPVKsPAAPyFLGssFsPVRC
P30291	S53	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	WEE1	CEEEEEEEEEEGSGHSTGEDsAFQEPDSPLPPARsPTEPGP
P30305	S209	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	GEDKENDGFVFKMPWKPTHPsSTHALAEWAsRREAFAQRPs
P30305	S291	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	FVDILESDLKDDDAVPPGMEsLISAPLVKTLEKEEEKDLVM
P30305	S353	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	LKRLERPQDRDTPVQNKRRRsVtPPEEQQEAEEPKARVLRs
P30305	S375	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	tPPEEQQEAEEPKARVLRsKsLCHDEIENLLDSDHRELIGD
P30305	S397	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	CHDEIENLLDSDHRELIGDYsKAFLLQtVDGKHQDLKYISP
P30305	S465	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	EYEGGHIKTAVNLPLERDAEsFLLKSPIAPCSLDKRVILIF
P30305	S50	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	PGLLLGSHGLLGsPVRAAASsPVttLtQtMHDLAGLGSETP
P30305	S513	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	RGPRMCRFIRERDRAVNDYPsLYYPEMYILKGGYKEFFPQH
P30305	T127	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	SDAGLCMDSPSPMDPHMAEQtFEQAIQAASRIIRNEQFAIR
P30305	T167	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	RRFQsMPVRLLGHsPVLRNItNsQAPDGRRKsEAGSGAAss
P30305	T265	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	VEELsPLALGRFSLTPAEGDtEEDDGFVDILESDLKDDDAV
P30305	T404	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	LLDSDHRELIGDYsKAFLLQtVDGKHQDLKYISPETMVALL
P30305	T58	GPS6\|EPSD\|PSP	CDC25B CDC25HU2	GLLGsPVRAAASsPVttLtQtMHDLAGLGSETPKSQVGTLL
P30307	S198	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	CDC25C	KNPNLGEDQAEEIsDELMEFsLKDQEAKVSRsGLYRsPsMP
P30307	S75	EPSD\|PSP	CDC25C	GDSANLsILsGGtPKRCLDLsNLSSGEITATQLTTSADLDE
P30622	S1364	EPSD\|PSP	CLIP1 CYLN1 RSN	VEMMSEAALNGNGDDLNNYDsDDQEKQsKKKPRLFCDICDC
P30622	S195	SIGNOR\|EPSD\|PSP	CLIP1 CYLN1 RSN	AAKEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIG
P30622	S312	SIGNOR\|EPSD\|PSP	CLIP1 CYLN1 RSN	KANAVRRVMATtsAsLKRsPsAssLsSMSSVASSVSSRPSR
P30626	T155	SIGNOR\|EPSD\|PSP	SRI	RLsPQAVNSIAKRYstNGKItFDDyIACCVKLRALtDSFRR
P31327	S808	Sugiyama	CPS1	IGSSMKsVGEVMAIGRTFEEsFQKALRMCHPsIEGFTPRLP
P31327	S863	Sugiyama	CPS1	LSEPSsTRIyAIAKAIDDNMsLDEIEKLTYIDKWFLYKMRD
P31327	S898	Sugiyama	CPS1	LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31327	T326	Sugiyama	CPS1	AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP
P31946	S47	Sugiyama	YWHAB	AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947	S45	Sugiyama	SFN HME1	FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948	S460	Sugiyama	STIP1	AMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRHD
P33981	S108	SIGNOR\|PSP	TTK MPS1 MPS1L1	IGRYSQAIEALPPDKYGQNEsFARIQVRFAELKAIQEPDDA
P33981	S214	SIGNOR\|PSP	TTK MPS1 MPS1L1	LLSEEEKKNLSASTVLtAQEsFSGSLGHLQNRNNSCDSRGQ
P33981	S291	SIGNOR\|PSP	TTK MPS1 MPS1L1	FGRVPVNLLNsPDCDVKtDDsVVPCFMKRQTSRSECRDLVV
P33981	S321	SIGNOR\|PSP	TTK MPS1 MPS1L1	TSRSECRDLVVPGSKPsGNDsCELRNLKSVQNsHFKEPLVS
P33981	S333	SIGNOR\|PSP	TTK MPS1 MPS1L1	GSKPsGNDsCELRNLKSVQNsHFKEPLVSDEKsSELIITDS
P33981	S345	SIGNOR\|PSP	TTK MPS1 MPS1L1	RNLKSVQNsHFKEPLVSDEKsSELIITDSITLKNKtEssLL
P33981	S362	SIGNOR\|PSP	TTK MPS1 MPS1L1	DEKsSELIITDSITLKNKtEssLLAKLEEtKEyQEPEVPEs
P33981	S363	SIGNOR\|PSP	TTK MPS1 MPS1L1	EKsSELIITDSITLKNKtEssLLAKLEEtKEyQEPEVPEsN
P33981	S37	SIGNOR\|PSP	TTK MPS1 MPS1L1	MNKVRDIKNKFKNEDLtDELsLNKIsADttDNsGtVNQIMM
P33981	T12	SIGNOR\|PSP	TTK MPS1 MPS1L1	_________MESEDLsGRELtIDsIMNKVRDIKNKFKNEDL
P33981	T210	SIGNOR\|PSP	TTK MPS1 MPS1L1	QKKQLLSEEEKKNLSASTVLtAQEsFSGSLGHLQNRNNSCD
P33981	T33	SIGNOR\|PSP	TTK MPS1 MPS1L1	IDsIMNKVRDIKNKFKNEDLtDELsLNKIsADttDNsGtVN
P33981	T371	SIGNOR\|PSP	TTK MPS1 MPS1L1	TDSITLKNKtEssLLAKLEEtKEyQEPEVPEsNQKQWQSKR
P33981	T458	SIGNOR\|PSP	TTK MPS1 MPS1L1	PISTSKWFDPKSICKtPssNtLDDYMsCFRtPVVKNDFPPA
P33981	T46	SIGNOR\|PSP	TTK MPS1 MPS1L1	KFKNEDLtDELsLNKIsADttDNsGtVNQIMMMANNPEDWL
P33981	T564	SIGNOR\|PSP	TTK MPS1 MPS1L1	NEKKQIYAIKYVNLEEADNQtLDSYRNEIAYLNKLQQHsDK
P33981	T594	SIGNOR\|PSP	TTK MPS1 MPS1L1	YLNKLQQHsDKIIRLYDYEItDQYIYMVMECGNIDLNSWLK
P33981	T676	PSP	TTK MPS1 MPS1L1	VDGMLKLIDFGIANQMQPDttsVVKDSQVGtVNYMPPEAIK
P34897	S417	Sugiyama	SHMT2	ERVLELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFR
P34931	S42	Sugiyama	HSPA1L	VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931	T228	Sugiyama	HSPA1L	DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931	T39	Sugiyama	HSPA1L	CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P34931	Y43	Sugiyama	HSPA1L	FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932	T365	Sugiyama	HSPA4 APG2 HSPH2	TRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAILsP
P35222	S60	PSP	CTNNB1 CTNNB OK/SW-cl.35 PRO2286	TtTAPsLsGKGNPEEEDVDTsQVLyEWEQGFSQsFTQEQVA
P35222	S718	SIGNOR\|EPSD\|PSP	CTNNB1 CTNNB OK/SW-cl.35 PRO2286	LDIGAQGEPLGYRQDDPsyRsFHSGGYGQDALGMDPMMEHE
P35568	S24	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	IRS1	PPEsDGFSDVRKVGYLRKPKsMHKRFFVLRAAsEAGGPARL
P35579	S1154	Sugiyama	MYH9	KRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKK
P35579	S1308	Sugiyama	MYH9	LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs
P35579	S1714	Sugiyama	MYH9	RAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQL
P35579	T1146	Sugiyama	MYH9	sRNKAEKQKRDLGEELEALKtELEDtLDstAAQQELRSKRE
P35579	T1151	Sugiyama	MYH9	EKQKRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNI
P35579	T1155	Sugiyama	MYH9	RDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKKT
P35579	T1313	Sugiyama	MYH9	DSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLstKLKQ
P35579	T1904	Sugiyama	MYH9	EEAQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRG
P35613	S278	Sugiyama	BSG UNQ6505/PRO21383	ITDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQ
P35613	S279	Sugiyama	BSG UNQ6505/PRO21383	TDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQy
P35869	S489	SIGNOR	AHR BHLHE76	LYPASSTSSTAPFENNFFNEsMNECRNWQDNTAPMGNDTIL
P35908	S191	Sugiyama	KRT2 KRT2A KRT2E	IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36507	S222	EPSD\|PSP	MAP2K2 MEK2 MKK2 PRKMK2	VNSRGEIKLCDFGVsGQLIDsMANsFVGtRSYMAPERLQGT
P36507	S226	EPSD\|PSP	MAP2K2 MEK2 MKK2 PRKMK2	GEIKLCDFGVsGQLIDsMANsFVGtRSYMAPERLQGTHYSV
P37840	S129	GPS6\|SIGNOR\|EPSD\|PSP	SNCA NACP PARK1	QEGILEDMPVDPDNEAyEMPsEEGyQDyEPEA_________
P38398	S1164	EPSD\|PSP	BRCA1 RNF53	QVCSETPDDLLDDGEIKEDtsFAENDIKESsAVFSKsVQKG
P38646	S212	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646	S89	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646	T116	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646	T120	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646	T94	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38646	Y118	Sugiyama	HSPA9 GRP75 HSPA9B mt-HSP70	ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39687	S27	Sugiyama	ANP32A C15orf1 LANP MAPM PHAP1	IHLELRNRtPsDVKELVLDNsRsNEGKLEGLTDEFEELEFL
P41091	T21	Sugiyama	EIF2S3 EIF2G	MAGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAt
P41227	S213	Sugiyama	NAA10 ARD1 ARD1A TE2	ACREEKGLAAEDsGGDsKDLsEVsEtTEstDVKDssEAsDs
P42677	S78	Sugiyama	RPS27 MPS1	GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42695	S1419	PSP	NCAPD3 CAPD3 KIAA0056	QESNGEIEHVTKRAIStPEKsISDVTFGAGVSYIGtPRtPs
P42898	T549	EPSD\|PSP	MTHFR	LKKYELRVNYHLVNVKGENItNAPELQPNAVTWGIFPGREI
P43034	S157	Sugiyama	PAFAH1B1 LIS1 MDCR MDS PAFAHA	yEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADMTIKLW
P43490	S180	Sugiyama	NAMPT PBEF PBEF1	TVATNSREQKKILAKyLLEtsGNLDGLEyKLHDFGyRGVSS
P45974	S783	Sugiyama	USP5 ISOT	IDDLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQL
P46531	S1791	SIGNOR\|PSP	NOTCH1 TAN1	EGFKVSEASKKKRREPLGEDsVGLKPLKNAsDGALMDDNQN
P46531	S2439	SIGNOR\|PSP	NOTCH1 TAN1	LGVSSAASGHLGRSFLSGEPsQADVQPLGPSSLAVHTILPQ
P46777	S224	Sugiyama	RPL5 MSTP030	VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46937	S405	Sugiyama	YAP1 YAP65	FLNsGtyHsRDEstDsGLsMssysVPRtPDDFLNsVDEMDT
P46937	T77	EPSD\|PSP	YAP1 YAP65	VRGDsEtDLEALFNAVMNPKtANVPQtVPMRLRKLPDsFFK
P47736	S525	SIGNOR\|EPSD\|PSP	RAP1GAP KIAA0474 RAP1GA1	NIQEVQEKREsPPAGQKtPDsGHVSQEPKSENSStQssPEM
P48643	S51	Sugiyama	CCT5 CCTE KIAA0098	LEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtVT
P48643	T269	Sugiyama	CCT5 CCTE KIAA0098	AILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMI
P48668	S176	Sugiyama	KRT6C KRT6E	IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741	S42	Sugiyama	HSPA7 HSP70B	VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P48741	T228	Sugiyama	HSPA7 HSP70B	DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P49023	S272	GPS6	PXN	QQQtRIsAssAtRELDELMAsLsDFKIQGLEQRADGERCWA
P49321	S497	Sugiyama	NASP	tEGsEEDDKENDKtEEMPNDsVLENKsLQENEEEEIGNLEL
P49327	S2465	Sugiyama	FASN FAS	LLRAKtGGAyGEDLGADyNLsQVCDGKVsVHVIEGDHRTLL
P49327	T2215	Sugiyama	FASN FAS	DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49411	T433	Sugiyama	TUFM	LRQPMILEKGQRFTLRDGNRtIGTGLVTNTLAMTEEEKNIK
P49588	T164	Sugiyama	AARS1 AARS	AGLEADLECKQIWQNLGLDDtKILPGNMKDNFWEMGDtGPC
P49589	S305	Sugiyama	CARS1 CARS	KLVPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKA
P49589	S746	Sugiyama	CARS1 CARS	KLFEAQEKLYKEyLQMAQNGsFQ__________________
P49792	S1613	Sugiyama	RANBP2 NUP358	KAPKSGFEGMFTKKEGQWDCsVCLVRNEASATKCIACQNPG
P49840	Y279	Sugiyama	GSK3A	LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841	Y216	Sugiyama	GSK3B	LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49959	S649	SIGNOR\|EPSD\|PSP	MRE11 HNGS1 MRE11A	QQPSRNVTTKNYsEVIEVDEsDVEEDIFPTTSKTDQRWSST
P49959	S688	EPSD\|PSP	MRE11 HNGS1 MRE11A	STSSSKIMsQsQVsKGVDFEssEDDDDDPFMNTSSLRRNRR
P50395	T407	Sugiyama	GDI2 RABGDIB	LVPKDLGtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGs
P50395	T408	Sugiyama	GDI2 RABGDIB	VPKDLGtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsE
P50395	T412	Sugiyama	GDI2 RABGDIB	LGtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFE
P50395	T413	Sugiyama	GDI2 RABGDIB	GtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFEE
P50416	T370	Sugiyama	CPT1A CPT1	DGRLLKPREMEQQMQRILDNtsEPQPGEARLAALTAGDRVP
P50542	S167	Sugiyama	PEX5 PXR1	EVTDPLSVSPARWAEEyLEQsEEKLWLGEPEGTATDRWYDE
P50570	T642	Sugiyama	DNM2 DYN2	RAGVYPEKDQAENEDGAQENtFsMDPQLERQVETIRNLVDS
P50851	S1247	Sugiyama	LRBA BGL CDC4L LBA	DCHGsVSEAssEQKIAKLDVsNVAtDtERLELKAsPNVEAP
P50897	S262	Sugiyama	PPT1 CLN1 PPT	EWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLVF
P50990	S23	Sugiyama	CCT8 C21orf112 CCTQ KIAA0002	LHVPKAPGFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTT
P51532	S1380	Sugiyama	SMARCA4 BAF190A BRG1 SNF2B SNF2L4	EEEEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEI
P51532	S1382	Sugiyama	SMARCA4 BAF190A BRG1 SNF2B SNF2L4	EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE
P51587	S193	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	BRCA2 FACD FANCD1	GRQTPKHISESLGAEVDPDMsWSSSLATPPtLsstVLIVRN
P51587	S205	SIGNOR\|EPSD\|PSP	BRCA2 FACD FANCD1	GAEVDPDMsWSSSLATPPtLsstVLIVRNEEASETVFPHDT
P51587	S206	SIGNOR\|EPSD\|PSP	BRCA2 FACD FANCD1	AEVDPDMsWSSSLATPPtLsstVLIVRNEEASETVFPHDTT
P51587	S239	iPTMNet\|EPSD	BRCA2 FACD FANCD1	TVFPHDTTANVKSYFSNHDEsLKKNDRFIASVTDsENTNQR
P51587	T203	SIGNOR\|EPSD\|PSP	BRCA2 FACD FANCD1	SLGAEVDPDMsWSSSLATPPtLsstVLIVRNEEASETVFPH
P51587	T207	SIGNOR\|EPSD\|PSP	BRCA2 FACD FANCD1	EVDPDMsWSSSLATPPtLsstVLIVRNEEASETVFPHDTTA
P52565	T7	SIGNOR	ARHGDIA GDIA1	______________MAEQEPtAEQLAQIAAENEEDEHsVNy
P52565	T91	SIGNOR	ARHGDIA GDIA1	VVTGLTLVCSSAPGPLELDLtGDLEsFKKQsFVLKEGVEYR
P52789	S889	Sugiyama	HK2	PHFAKVMHETVKDLAPKCDVsFLQsEDGSGKGAALITAVAC
P52907	S215	Sugiyama	CAPZA1	QVHYYEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENA
P52948	S683	Sugiyama	NUP98 ADAR2	IAKPIPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEG
P53350	S450	Sugiyama	PLK1 PLK	NSVGVLFNDSTRLILyNDGDsLQYIERDGTESYLTVSSHPN
P53350	S71	Sugiyama	PLK1 PLK	RRYVRGRFLGKGGFAKCFEIsDADTKEVFAGKIVPKSLLLK
P53350	T210	PSP	PLK1 PLK	VKIGDFGLATKVEYDGERKKtLCGtPNyIAPEVLSKKGHSF
P53999	S118	Sugiyama	SUB1 PC4 RPO2TC1	PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P53999	S12	Sugiyama	SUB1 PC4 RPO2TC1	_________MPKSKELVsssssGsDsDsEVDKKLKRKKQVA
P54105	T223	Sugiyama	CLNS1A CLCI ICLN	AGVRtEDsIRDyEDGMEVDttPtVAGQFEDADVDH______
P54274	S435	GPS6\|SIGNOR\|EPSD\|PSP	TERF1 PIN2 TRBF1 TRF TRF1	RTSVMLKDRWRTMKKLKLISsDsED________________
P54646	T172	PSP	PRKAA2 AMPK AMPK2	NAKIADFGLSNMMsDGEFLRtsCGsPNyAAPEVISGRLYAG
P54652	S41	Sugiyama	HSPA2	VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652	T229	Sugiyama	HSPA2	DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652	T38	Sugiyama	HSPA2	CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P54652	Y42	Sugiyama	HSPA2	FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55010	T227	Sugiyama	EIF5	ttEEAQRRRMDEISDHAKVLtLsDDLERtIEERVNILFDFV
P55010	T235	Sugiyama	EIF5	RMDEISDHAKVLtLsDDLERtIEERVNILFDFVKKKKEEGV
P55036	S266	Sugiyama	PSMD4 MCB1	AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ
P55060	S366	Sugiyama	CSE1L CAS XPO2	KVIVPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAA
P55072	T76	PSP	VCP HEL-220 HEL-S-70	TVLLKGKKRREAVCIVLSDDtCSDEKIRMNRVVRNNLRVRL
P55884	S185	Sugiyama	EIF3B EIF3S9	EEELLGDVLKDRPQEADGIDsVIVVDNVPQVGPDRLEKLKN
P57721	S82	Sugiyama	PCBP3 PCBP3-OT1 PCBP3OT	GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK
P60484	S380	EPSD\|PSP	PTEN MMAC1 TEP1	SSsTSVtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQI
P60484	T382	EPSD\|PSP	PTEN MMAC1 TEP1	sTSVtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQItK
P60484	T383	EPSD\|PSP	PTEN MMAC1 TEP1	TSVtPDVsDNEPDHyRYsDttDsDPENEPFDEDQHtQItKV
P60660	T103	Sugiyama	MYL6	QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660	T22	Sugiyama	MYL6	CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN
P60709	S199	Sugiyama	ACTB	DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709	S239	Sugiyama	ACTB	VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709	S300	Sugiyama	ACTB	NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P60709	S323	Sugiyama	ACTB	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709	S365	Sugiyama	ACTB	ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P60709	S368	Sugiyama	ACTB	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709	S52	Sugiyama	ACTB	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709	S60	Sugiyama	ACTB	HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709	T297	Sugiyama	ACTB	TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709	T303	Sugiyama	ACTB	MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P60709	T304	Sugiyama	ACTB	KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709	T318	Sugiyama	ACTB	VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709	Y294	Sugiyama	ACTB	IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ
P60709	Y53	Sugiyama	ACTB	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P61769	S75	Sugiyama	B2M CDABP0092 HDCMA22P	IEVDLLKNGERIEKVEHsDLsFsKDWSFYLLYYTEFTPTEK
P61978	S401	Sugiyama	HNRNPK HNRPK	GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978	S75	Sugiyama	HNRNPK HNRPK	GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61978	S77	Sugiyama	HNRNPK HNRPK	VIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIETI
P61981	S46	Sugiyama	YWHAG	AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981	T231	Sugiyama	YWHAG	LNEDsyKDstLIMQLLRDNLtLWtsDQQDDDGGEGNN____
P61981	T31	Sugiyama	YWHAG	ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN
P62249	S9	Sugiyama	RPS16	____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258	S148	Sugiyama	YWHAE	YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258	S46	Sugiyama	YWHAE	SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62277	S14	Sugiyama	RPS13	_______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280	T54	Sugiyama	RPS11	PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62736	S241	Sugiyama	ACTA2 ACTSA ACTVS GIG46	VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736	S325	Sugiyama	ACTA2 ACTSA ACTVS GIG46	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736	S54	Sugiyama	ACTA2 ACTSA ACTVS GIG46	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736	S62	Sugiyama	ACTA2 ACTSA ACTVS GIG46	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736	T320	Sugiyama	ACTA2 ACTSA ACTVS GIG46	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736	Y55	Sugiyama	ACTA2 ACTSA ACTVS GIG46	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62826	S135	SIGNOR\|EPSD\|PSP	RAN ARA24 OK/SW-cl.81	IPIVLCGNKVDIKDRKVKAKsIVFHRKKNLQyyDIsAKSNy
P62826	T66	Sugiyama	RAN ARA24 OK/SW-cl.81	EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62857	T38	Sugiyama	RPS28	LGRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtL
P62899	S15	Sugiyama	RPL31	______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG
P62937	T157	Sugiyama	PPIA CYPA	NIVEAMERFGsRNGKTSKKItIADCGQLE____________
P62942	T7	Sugiyama	FKBP1A FKBP1 FKBP12	______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979	S134	Sugiyama	RPS27A UBA80 UBCEP1	IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P63104	S145	Sugiyama	YWHAZ	YYRyLAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHP
P63104	S156	Sugiyama	YWHAZ	DDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV
P63104	S28	Sugiyama	YWHAZ	QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104	S45	Sugiyama	YWHAZ	CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63146	S148	Sugiyama	UBE2B RAD6B UBCH1	QLYQENKREYEKRVsAIVEQsWNDS________________
P63167	S14	Sugiyama	DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1	_______MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNI
P63220	S68	Sugiyama	RPS21	GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261	S199	Sugiyama	ACTG1 ACTG	DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261	S239	Sugiyama	ACTG1 ACTG	VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261	S300	Sugiyama	ACTG1 ACTG	NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P63261	S323	Sugiyama	ACTG1 ACTG	ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261	S365	Sugiyama	ACTG1 ACTG	ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P63261	S368	Sugiyama	ACTG1 ACTG	sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261	S52	Sugiyama	ACTG1 ACTG	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261	S60	Sugiyama	ACTG1 ACTG	HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261	T297	Sugiyama	ACTG1 ACTG	TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261	T303	Sugiyama	ACTG1 ACTG	MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P63261	T304	Sugiyama	ACTG1 ACTG	KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261	T318	Sugiyama	ACTG1 ACTG	VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261	Y294	Sugiyama	ACTG1 ACTG	IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ
P63261	Y53	Sugiyama	ACTG1 ACTG	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267	S240	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267	S324	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267	S53	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267	S61	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267	T319	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267	Y54	Sugiyama	ACTG2 ACTA3 ACTL3 ACTSG	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809	S136	Sugiyama	YBX1 NSEP1 YB1	GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P67809	S314	Sugiyama	YBX1 NSEP1 YB1	NPKPQDGKETKAADPPAENssAPEAEQGGAE__________
P67809	T126	Sugiyama	YBX1 NSEP1 YB1	GEtVEFDVVEGEKGAEAANVtGPGGVPVQGsKYAADRNHYR
P67936	T237	Sugiyama	TPM4	IDDLEEKLAQAKEENVGLHQtLDQtLNELNCI_________
P67936	T241	Sugiyama	TPM4	EEKLAQAKEENVGLHQtLDQtLNELNCI_____________
P68032	S241	Sugiyama	ACTC1 ACTC	VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032	S325	Sugiyama	ACTC1 ACTC	tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032	S54	Sugiyama	ACTC1 ACTC	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032	S62	Sugiyama	ACTC1 ACTC	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032	T320	Sugiyama	ACTC1 ACTC	VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032	Y55	Sugiyama	ACTC1 ACTC	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68133	S241	Sugiyama	ACTA1 ACTA	VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133	S325	Sugiyama	ACTA1 ACTA	TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133	S54	Sugiyama	ACTA1 ACTA	PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133	S62	Sugiyama	ACTA1 ACTA	HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133	T320	Sugiyama	ACTA1 ACTA	VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133	Y55	Sugiyama	ACTA1 ACTA	sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363	S439	Sugiyama	TUBA1B	SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
P68363	S48	Sugiyama	TUBA1B	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363	T41	Sugiyama	TUBA1B	WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P68363	T51	Sugiyama	TUBA1B	QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P68363	T73	Sugiyama	TUBA1B	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363	T80	Sugiyama	TUBA1B	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P78371	S60	Sugiyama	CCT2 99D8.1 CCTB	KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371	T474	Sugiyama	CCT2 99D8.1 CCTB	AGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGIT
P78371	T475	Sugiyama	CCT2 99D8.1 CCTB	GYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGITE
P78371	T69	Sugiyama	CCT2 99D8.1 CCTB	DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P78527	S3205	PSP	PRKDC HYRC HYRC1	NRCFFLSKIEEKLtPLPEDNsMNVDQDGDPsDRMEVQEQEE
P83731	S38	Sugiyama	RPL24	GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P84098	S37	Sugiyama	RPL19	CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098	T29	Sugiyama	RPL19	RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
Q00613	S216	SIGNOR\|EPSD\|PSP	HSF1 HSTF1	LVQSNRILGVKRKIPLMLNDsGsAHSMPKYSRQFsLEHVHG
Q00613	S419	GPS6\|PSP	HSF1 HSTF1	QTMLSSHGFSVDTSALLDLFsPSVTVPDMSLPDLDSSLASI
Q00839	S59	EPSD\|PSP	HNRNPU C1orf199 HNRPU SAFA U21.1	QAALDDEEAGGRPAMEPGNGsLDLGGDsAGRSGAGLEQEAA
Q00987	S260	SIGNOR\|EPSD\|PSP	MDM2	sVsDQFsVEFEVEsLDsEDYsLsEEGQELsDEDDEVyQVtV
Q01082	S1388	Sugiyama	SPTBN1 SPTB2	TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy
Q01105	S161	Sugiyama	SET	FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01105	T169	Sugiyama	SET	NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q01518	S338	Sugiyama	CAP1 CAP	EPAVLELEGKKWRVENQENVsNLVIEDTELKQVAYIYKCVN
Q01538	S429	EPSD	MYT1 KIAA0835 KIAA1050 MTF1 MYTI PLPB1	GLGEPGKAAKPLDTVRKSYYsKDPSRAEKREIKCPTPGCDG
Q01546	S196	Sugiyama	KRT76 KRT2B KRT2P	IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q02750	S218	EPSD\|PSP	MAP2K1 MEK1 PRKMK1	VNSRGEIKLCDFGVsGQLIDsMANsFVGtRSYMsPERLQGT
Q02750	S222	EPSD\|PSP	MAP2K1 MEK1 PRKMK1	GEIKLCDFGVsGQLIDsMANsFVGtRSYMsPERLQGTHYSV
Q04760	T35	Sugiyama	GLO1	AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM
Q04917	S46	Sugiyama	YWHAH YWHA1	AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q06323	S55	Sugiyama	PSME1 IFI5111	KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE
Q06609	S14	EPSD\|PSP	RAD51 RAD51A RECA	_______MAMQMQLEANADtsVEEESFGPQPISRLEQCGIN
Q07020	T136	Sugiyama	RPL18	AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07021	S210	Sugiyama	C1QBP GC1QBP HABP1 SF2P32	EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS
Q07817	S62	EPSD\|PSP	BCL2L1 BCL2L BCLX	ESEMEtPsAINGNPSWHLADsPAVNGATGHSSSLDAREVIP
Q08050	S730	GPS6\|SIGNOR\|EPSD\|PSP	FOXM1 FKHL16 HFH11 MPP2 WIN	sGLAANRsLtEGLVLDtMNDsLsKILLDIsFPGLDEDPLGP
Q08050	S739	GPS6\|SIGNOR\|EPSD\|PSP	FOXM1 FKHL16 HFH11 MPP2 WIN	tEGLVLDtMNDsLsKILLDIsFPGLDEDPLGPDNINWSQFI
Q08211	S625	Sugiyama	DHX9 DDX9 LKP NDH2	DANCNLICGDEyGPETRLsMsQLNEKETPFELIEALLKYIE
Q08J23	T755	Sugiyama	NSUN2 SAKI TRM4	GQRAGEPNsPDAEEANsPDVtAGCDPAGVHPPR________
Q12834	S170	SIGNOR\|PSP	CDC20	VLYsQKAtPGSsRKTCRYIPsLPDRILDAPEIRNDYYLNLV
Q12888	S1618	SIGNOR\|EPSD\|PSP	TP53BP1	EQYGLGPYEAVtPLtKAADIsLDNLVEGKRKRRsNVssPAt
Q13042	S112	EPSD\|PSP	CDC16 ANAPC6	VLDMEEPINKRLFEKYLKDEsGFKDPSSDWEMSQSSIKSSI
Q13127	S1030	PSP	REST NRSF XBR	GIHSHEGSDLSDNMsEGsDDsGLHGARPVPQESSRKNAKEA
Q13158	S194	SIGNOR\|EPSD\|PSP	FADD MORT1 GIG3	ADLVQEVQQARDLQNRsGAMsPMsWNsDAsTSEAS______
Q13188	S15	SIGNOR\|PSP	STK3 KRS1 MST2	______MEQPPAPKSKLKKLsEDsLtKQPEEVFDVLEKLGE
Q13188	S18	PSP	STK3 KRS1 MST2	___MEQPPAPKSKLKKLsEDsLtKQPEEVFDVLEKLGEGsY
Q13188	S316	PSP	STK3 KRS1 MST2	EIKAKRHEEQQRELEEEEENsDEDELDsHtMVKTSVESVGt
Q13263	S479	Sugiyama	TRIM28 KAP1 RNF96 TIF1B	ssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERLDLDLtA
Q13416	S188	EPSD\|PSP	ORC2 ORC2L	KRLIVPRSHSDSESEYSASNsEDDEGVAQEHEEDTNAVIFS
Q13485	T197	SIGNOR\|PSP	SMAD4 DPC4 MADH4	HSIQTIQHPPSNRASTETyStPALLAPSESNATSTANFPNI
Q13526	S65	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	PIN1	GKNGQGEPARVRCSHLLVKHsQSRRPsSWRQEKITRTKEEA
Q13541	S112	Sugiyama	EIF4EBP1	EAsQsHLRNsPEDKRAGGEEsQFEMDI______________
Q13765	S132	Sugiyama	NACA HSD48	YKSPAsDtyIVFGEAKIEDLsQQAQLAAAEKFKVQGEAVsN
Q13765	S186	Sugiyama	NACA HSD48	sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI
Q13765	S191	Sugiyama	NACA HSD48	VDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDIVNAIM
Q13765	T119	Sugiyama	NACA HSD48	SKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAA
Q14151	S194	Sugiyama	SAFB2 KIAA0138	PAQPPEHAVDGEGFKNtLEtssLNFKVtPDIEEsLLEPENE
Q14157	T256	Sugiyama	UBAP2L KIAA0144 NICE4	AWRtAtEEWGtEDWNEDLsEtKIFtAsNVssVPLPAENVtI
Q14203	S179	SIGNOR\|EPSD\|PSP	DCTN1	GVAGASSSLGPSGSASAGELsSSEPSTPAQTPLAAPIIPTP
Q14204	T1307	Sugiyama	DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325	FGRLKDDREKCAKAKEALELtDtGLLsGSEERVQVALEELQ
Q14247	T328	Sugiyama	CTTN EMS1	GKyGVQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKts
Q14257	S146	Sugiyama	RCN2 ERC55	MyDRVIDFDENtALDDAEEEsFRKLHLKDKKRFEKANQDSG
Q14257	T137	Sugiyama	RCN2 ERC55	VTWDEyNIQMyDRVIDFDENtALDDAEEEsFRKLHLKDKKR
Q14444	T303	Sugiyama	CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105	YTEQSEVESTEYVNRQFMAEtQFtsGEKEQVDEWTVETVEV
Q14568	S53	Sugiyama	HSP90AA2P HSP90AA2 HSPC2 HSPCAL3	IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14674	S1399	SIGNOR\|EPSD\|PSP	ESPL1 ESP1 KIAA0165	QAPRVQQRVQTRLKVNFsDDsDLEDPVSAEAWLAEEPKRRG
Q14674	T1363	SIGNOR\|EPSD\|PSP	ESPL1 ESP1 KIAA0165	LPCtPKPPDRIRQAGPHVPFtVFEEVCPTESKPEVPQAPRV
Q14676	S20	PSP	MDC1 KIAA0170 NFBD1	_MEDtQAIDWDVEEEEETEQsSESLRCNVEPVGRLHIFSGA
Q14676	T4	PSP	MDC1 KIAA0170 NFBD1	_________________MEDtQAIDWDVEEEEETEQsSESL
Q14676	T847	PSP	MDC1 KIAA0170 NFBD1	ERGPLERETEKLLPERQTDVtGEEELTKGKQDREQKQLLAR
Q14677	S164	Sugiyama	CLINT1 ENTH EPN4 EPNR KIAA0171	RLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKW
Q14677	S166	Sugiyama	CLINT1 ENTH EPN4 EPNR KIAA0171	REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14677	T215	Sugiyama	CLINT1 ENTH EPN4 EPNR KIAA0171	FPFSDKLGELsDKIGstIDDtIsKFRRKDREDsPERCsDsD
Q14697	S913	Sugiyama	GANAB G2AN KIAA0088	VIIGAGKPAAVVLQTKGSPEsRLsFQHDPEtsVLVLRKPGI
Q14697	T923	Sugiyama	GANAB G2AN KIAA0088	VVLQTKGSPEsRLsFQHDPEtsVLVLRKPGINVASDWSIHL
Q14790	S305	SIGNOR\|PSP	CASP8 MCH5	DDCTVEQIYEILKIYQLMDHsNMDCFICCILSHGDKGIIYG
Q14978	S637	Sugiyama	NOLC1 KIAA0035 NS5ATP13	GEKRAssPFRRVREEEIEVDsRVADNsFDAKRGAAGDWGER
Q14980	S1183	Sugiyama	NUMA1 NMP22 NUMA	ALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQDHS
Q14CN4	S138	Sugiyama	KRT72 K6IRS2 KB35 KRT6 KRT6IRS2	IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15013	S102	GPS6\|SIGNOR\|PSP	MAD2L1BP CMT2 KIAA0110	YQRQQLPLPYEQLKHFYRKPsPQAEEMLKKKPRATTEVSSR
Q15013	S246	GPS6	MAD2L1BP CMT2 KIAA0110	FRPKLNYRVPSRGHKLTVTLsCGRPSIRTTAWEDYIWFQAP
Q15022	S539	SIGNOR\|EPSD\|PSP	SUZ12 CHET9 JJAZ1 KIAA0160	PVKRTPITHILVCRPKRTKAsMsEFLEsEDGEVEQQRTYSS
Q15022	S541	SIGNOR\|EPSD\|PSP	SUZ12 CHET9 JJAZ1 KIAA0160	KRTPITHILVCRPKRTKAsMsEFLEsEDGEVEQQRTYSSGH
Q15022	S546	SIGNOR\|EPSD\|PSP	SUZ12 CHET9 JJAZ1 KIAA0160	THILVCRPKRTKAsMsEFLEsEDGEVEQQRTYSSGHNRLYF
Q15056	S110	Sugiyama	EIF4H KIAA0038 WBSCR1 WSCR1	DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15084	S169	Sugiyama	PDIA6 ERP5 P5 TXNDC7	GKQGRSDsSSKKDVIELtDDsFDKNVLDSEDVWMVEFYAPW
Q15185	S118	Sugiyama	PTGES3 P23 TEBP	WLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGDEDVDL
Q15208	T183	SIGNOR\|PSP	STK38 NDR1	YLIMEFLPGGDMMTLLMKKDtLTEEETQFYIAETVLAIDSI
Q15208	T407	SIGNOR\|PSP	STK38 NDR1	WEHIRERPAAIsIEIKSIDDtSNFDEFPESDILKPTVATSN
Q15208	T7	SIGNOR\|PSP	STK38 NDR1	______________MAMTGstPCssMSNHTKERVTMTKVTL
Q15293	S69	Sugiyama	RCN1 RCN	PPEDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVD
Q15365	S50	Sugiyama	PCBP1	GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK
Q15366	S50	Sugiyama	PCBP2	GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK
Q15398	S777	Sugiyama	DLGAP5 DLG7 KIAA0008	sItSQDVLMssPEKNTAsQNsILEEGEtKIsQsELFDNKsL
Q15427	T14	Sugiyama	SF3B4 SAP49	_______MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFL
Q15435	S24	EPSD\|PSP	PPP1R7 SDS22	ERGAGQQQsQEMMEVDRRVEsEEsGDEEGKKHssGIVADLs
Q15435	S27	EPSD\|PSP	PPP1R7 SDS22	AGQQQsQEMMEVDRRVEsEEsGDEEGKKHssGIVADLsEQs
Q15435	S44	EPSD\|PSP	PPP1R7 SDS22	sEEsGDEEGKKHssGIVADLsEQsLKDGEERGEEDPEEEHE
Q15435	S47	EPSD\|PSP	PPP1R7 SDS22	sGDEEGKKHssGIVADLsEQsLKDGEERGEEDPEEEHELPV
Q15435	T277	EPSD\|PSP	PPP1R7 SDS22	LYLSHNGIEVIEGLENNNKLtMLDIASNRIKKIENISHLTE
Q15468	S1108	EPSD\|PSP	STIL SIL	NNCDPFSLLHINTDRSTVGLsLIsPNNMsFATKKYMKRYGL
Q15468	S1116	EPSD\|PSP	STIL SIL	LHINTDRSTVGLsLIsPNNMsFATKKYMKRYGLLQssDNsE
Q15545	S200	Sugiyama	TAF7 TAF2F TAFII55	RWEIIAEDETKEAENQGLDIssPGMsGHRQGHDsLEHDELR
Q15785	S51	Sugiyama	TOMM34 URCC3	LyGRALRVLQAQGssDPEEEsVLysNRAACHLKDGNCRDCI
Q16143	S118	SIGNOR\|EPSD\|PSP	SNCB	VAQEAAEEPLIEPLMEPEGEsYEDPPQEEyQEYEPEA____
Q16513	S590	Sugiyama	PKN2 PRK2 PRKCL2	LEPEPPPAPPRAssLGEIDEssELRVLDIPGQDsEtVFDIQ
Q16531	T1125	Sugiyama	DDB1 XAP1	MQEVVANLQYDDGSGMKREAtADDLIKVVEELtRIH_____
Q16576	T10	Sugiyama	RBBP7 RBAP46	___________MAsKEMFEDtVEERVINEEYKIWKKNTPFL
Q17RH5	S1010	PSP	RAPGEF2	PATNTLPKNPGDKKPVKSETsPVAPRAGSQQKAQSLPQPQQ
Q17RH5	S1164	PSP	RAPGEF2	SNSSFDSVPVSLHDERRQRHsVSIVETNLGMGRMERRTMIE
Q17RH5	S794	PSP	RAPGEF2	KIIKHFIKIALHCRECKNFNsMFAIISGLNLAPVARLRTTW
Q17RH5	S921	PSP	RAPGEF2	VNMDPALMFRTRKKKWRSLGsLSQGSTNATVLDVAQTGGHK
Q17RH5	T632	PSP	RAPGEF2	ISKDTTAKEVVIQAIREFAVtATPDQYSLCEVSVTPEGVIK
Q27J81	S1202	Sugiyama	INF2 C14orf151 C14orf173	EsALDtsLDKsFsEDAVtDssGsGtLPRARGRASKGTGKRR
Q27J81	T1039	Sugiyama	INF2 C14orf151 C14orf173	PAGDPVGSTRCPASEPGLDAtTASESRGWDLVDAVtPGPQP
Q2M2Z5	T379	GPS6\|SIGNOR\|EPSD\|PSP	KIZ C20orf19 NCRNA00153 PLK1S1 HT013	KPFRKMQEEEEESWSTSSDLtISISEDDLILESPEPQPNPG
Q2NKX8	T1063	GPS6\|EPSD\|PSP	ERCC6L PICH	INPFNTSLFQFSsVKQFDAStPKNDIsPPGRFFssQIPssV
Q2VIR3	T21	Sugiyama	EIF2S3B	MAGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAt
Q38SD2	S1817	SIGNOR\|EPSD\|PSP	LRRK1 KIAA1790	PAASHTANPKVPEGDSIADVsIMYSEELGTQILIHQESLTD
Q3KR16	T574	SIGNOR\|EPSD\|PSP	PLEKHG6	AEGRTPEFSTIIPHLVVTEDtDEDAPLVPDDTSDSGYGTLI
Q3SY84	S143	Sugiyama	KRT71 K6IRS1 KB34 KRT6IRS1	IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q49MG5	S289	GPS6\|SIGNOR\|EPSD\|PSP	MAP9 ASAP	PNEEITENHNSLKSDENKENsFSADHVTTAVEKSKEsQVTA
Q53EZ4	S436	GPS6\|SIGNOR\|iPTMNet\|EPSD\|PSP	CEP55 C10orf3 URCC6	TENREKVAAsPKsPtAALNEsLVECPKCNIQYPATEHRDLL
Q53GL7	T601	SIGNOR\|PSP	PARP10	DSTGGDQEDVSLEEVRELLAtLEGLDLDGEDWLPRELEEEG
Q562R1	S240	Sugiyama	ACTBL2	VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q58FF6	T165	Sugiyama	HSP90AB4P	DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG
Q58FF7	S370	Sugiyama	HSP90AB3P HSP90BC	KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7	S58	Sugiyama	HSP90AB3P HSP90BC	IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF7	S63	Sugiyama	HSP90AB3P HSP90BC	LISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERT
Q58FF7	S67	Sugiyama	HSP90AB3P HSP90BC	ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERTLALV
Q58FF7	T169	Sugiyama	HSP90AB3P HSP90BC	DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
Q58FF8	S58	Sugiyama	HSP90AB2P HSP90BB	IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8	S63	Sugiyama	HSP90AB2P HSP90BB	LISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQEHT
Q58FF8	S67	Sugiyama	HSP90AB2P HSP90BB	ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQEHTLTLV
Q5H9R7	S579	Sugiyama	PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3	IDQFGFNDEKFADQDDIGNVsFDRVSDINFTLNTNESGNIA
Q5H9R7	S868	Sugiyama	PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3	RPPsssPEQRTGQPSAPGDtsVNGPV_______________
Q5T035	T62	Sugiyama	FAM120A2P C9orf129	yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER
Q5T3I0	S272	Sugiyama	GPATCH4 GPATC4	VsDEREGTTKGNEKEDAAGtsGLGELNSREQtNQSLRKGKK
Q5XKE5	S155	Sugiyama	KRT79 K6L KB38 KRT6L	IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6IBW4	S288	EPSD\|PSP	NCAPH2 CAPH2	PEASAPKAALEPKEsRsPQQsAALPRRYMLREREGAPEPAs
Q6PEY2	S48	Sugiyama	TUBA3E	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2	T41	Sugiyama	TUBA3E	WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q6PEY2	T51	Sugiyama	TUBA3E	QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q6PGQ7	S497	SIGNOR\|EPSD\|PSP	BORA C13orf34	MSPLAESSVIPCESSNIQMDsGYNtQNCGSNIMDTVGAESY
Q6PGQ7	T501	SIGNOR\|EPSD\|PSP	BORA C13orf34	AESSVIPCESSNIQMDsGYNtQNCGSNIMDTVGAESYCKES
Q6S8J3	S1065	Sugiyama	POTEE A26C1A POTE2	ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q6S8J3	S1068	Sugiyama	POTEE A26C1A POTE2	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3	S939	Sugiyama	POTEE A26C1A POTE2	VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6UXH1	S295	Sugiyama	CRELD2 UNQ185/PRO211	KECISGYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSY
Q6UXH1	T300	Sugiyama	CRELD2 UNQ185/PRO211	GYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSYVCVCP
Q6ZMR3	S161	Sugiyama	LDHAL6A LDHL2	DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q71F23	S77	SIGNOR\|EPSD\|PSP	CENPU ICEN24 KLIP1 MLF1IP PBIP1	RLGENEKDEETYETFDPPLHstAIYADEEEFSKHCGLsLss
Q71F23	T78	GPS6\|SIGNOR\|EPSD\|PSP	CENPU ICEN24 KLIP1 MLF1IP PBIP1	LGENEKDEETYETFDPPLHstAIYADEEEFSKHCGLsLsst
Q71U36	S439	Sugiyama	TUBA1A TUBA3	SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
Q71U36	S48	Sugiyama	TUBA1A TUBA3	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36	T41	Sugiyama	TUBA1A TUBA3	WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q71U36	T51	Sugiyama	TUBA1A TUBA3	QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q71U36	T73	Sugiyama	TUBA1A TUBA3	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36	T80	Sugiyama	TUBA1A TUBA3	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71UM5	S78	Sugiyama	RPS27L	GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q76N32	S332	SIGNOR\|PSP	CEP68 KIAA0582	GPQLPKHLDSRVPADPVLQDsGVDLDSFSVSPASTLKsPtN
Q7L2Z9	S138	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	LQQCEtLKVPPKKMEDLtNVssLLNMERARDKANEEGLALL
Q7L2Z9	S139	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	QQCEtLKVPPKKMEDLtNVssLLNMERARDKANEEGLALLQ
Q7L2Z9	S248	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	ILALIPNQNALLKDLDILHNssQMKsMstFIEEAYKKLDAS
Q7L2Z9	S249	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	LALIPNQNALLKDLDILHNssQMKsMstFIEEAYKKLDAS_
Q7L2Z9	S253	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	PNQNALLKDLDILHNssQMKsMstFIEEAYKKLDAS_____
Q7L2Z9	S255	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	QNALLKDLDILHNssQMKsMstFIEEAYKKLDAS_______
Q7L2Z9	T123	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	KEEIQYHLNFLKKRLLQQCEtLKVPPKKMEDLtNVssLLNM
Q7L2Z9	T135	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	KRLLQQCEtLKVPPKKMEDLtNVssLLNMERARDKANEEGL
Q7L2Z9	T256	SIGNOR\|EPSD\|PSP	CENPQ C6orf139	NALLKDLDILHNssQMKsMstFIEEAYKKLDAS________
Q7RTS7	S153	Sugiyama	KRT74 K6IRS4 KB37 KRT5C KRT6IRS4	IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z2W4	S492	Sugiyama	ZC3HAV1 ZC3HDC2 PRO1677	VQATGRIADDADPRVALVNDsLsDVtsTtssRVDDHDSEEI
Q7Z3K3	S28	Sugiyama	POGZ KIAA0461 SUHW5 ZNF280E ZNF635 Nbla00003	MECEEEELEPWQKISDVIEDsVVEDyNsVDKTTTVSVSQQP
Q7Z794	S177	Sugiyama	KRT77 KRT1B	IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86VS8	S230	Sugiyama	HOOK3	QEEKSSLLAENQVLMERLNQsDsIEDPNsPAGRRHLQLQTQ
Q86Y46	S145	Sugiyama	KRT73 K6IRS3 KB36 KRT6IRS3	IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IUD2	S824	Sugiyama	ERC1 ELKS KIAA1081 RAB6IP2	KKKsAQMLEEARRREDNLNDsSQQLQDSLRKKDDRIEELEE
Q8IWB6	S437	SIGNOR\|EPSD\|PSP	TEX14 SGK307	TQLYNWAAPEVILQKAATVKsDIYSFSMIMQEILTDDIPWK
Q8IYE1	S680	Sugiyama	CCDC13	LTTRLAIQVEENEMLKAALGsALRGKEEDFRMYHEILGQVK
Q8IZD2	S861	EPSD\|PSP	KMT2E MLL5	ERsRsPAVNGENKsPLLLNDsCSLPDLTTPLKKRRFYQLLD
Q8N1F7	S72	Sugiyama	NUP93 KIAA0095	sQETADVKASVLLGsRGLDIsHIsQRLEsLsAAtTFEPLEP
Q8N4N8	S200	PSP	KIF2B	TRNPNYEIMHMIEEYRRHLDssKIsVLEPPQEHRICVCVRK
Q8N4N8	S201	PSP	KIF2B	RNPNYEIMHMIEEYRRHLDssKIsVLEPPQEHRICVCVRKR
Q8N4N8	S204	SIGNOR\|EPSD\|PSP	KIF2B	NYEIMHMIEEYRRHLDssKIsVLEPPQEHRICVCVRKRPLN
Q8N4N8	T125	SIGNOR\|EPSD\|PSP	KIF2B	AIRDQRTATKWVAMIPQKNQtASGDSLDVRVPSKPCLMKQK
Q8N684	S166	Sugiyama	CPSF7	PGKVLNGEKVDVRPAtRQNLsQFEAQARKRECVRVPRGGIP
Q8NBJ7	S256	Sugiyama	SUMF2 PSEC0171 UNQ1968/PRO4500	EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG
Q8NHV4	S397	GPS6\|SIGNOR\|EPSD\|PSP	NEDD1	sINTDtLSKEtDsGKNQDFssFDDtGKssLGDMFsPIRDDA
Q8NHV4	S426	GPS6\|SIGNOR\|EPSD\|PSP	NEDD1	LGDMFsPIRDDAVVNKGsDEsIGKGDGFDFLPQLNSVFPPR
Q8NHV4	S637	GPS6\|SIGNOR\|EPSD\|PSP	NEDD1	EMIKQFHMQLNEMHSLLERYsVNEGLVAEIERLREENKRLR
Q8NHV4	T382	GPS6\|SIGNOR\|EPSD\|PSP	NEDD1	GKGTVAVQEKAGLPRsINTDtLSKEtDsGKNQDFssFDDtG
Q8NHW5	S307	Sugiyama	RPLP0P6	AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
Q8TAM6	S280	Sugiyama	ERMN KIAA1189	TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TCG1	S904	EPSD\|PSP	CIP2A KIAA1524	MIAMIHSLSGGKINPETVNLsI___________________
Q8TD19	T210	SIGNOR\|PSP	NEK9 KIAA1995 NEK8 NERCC	IKLGDYGLAKKLNSEYSMAEtLVGtPYYMSPELCQGVKYNF
Q8TEP8	T44	SIGNOR\|PSP	CEP192 KIAA1569 PP8407	SGILENVTLSSNLGLPVAVStLARDRSSTDNRYPDIQASYL
Q8WU90	T345	Sugiyama	ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730	DsVsVNDIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDEN
Q8WVJ2	S153	Sugiyama	NUDCD2	GFDFsGAEIsGNytKGGPDFsNLEK________________
Q92574	S468	EPSD\|PSP	TSC1 KIAA0243 TSC	PGSKGSVTLSDLPGFLGDLAsEEDsIEKDKEEAAIsRELsE
Q92574	S579	EPSD\|PSP	TSC1 KIAA0243 TSC	CGSADESPAGDRECQTSLETsIFTPsPCKIPPPTRVGFGsG
Q92598	T795	Sugiyama	HSPH1 HSP105 HSP110 KIAA0201	DQDPVVRAQEIKTKIKELNNtCEPVVTQPKPKIEsPKLERt
Q92994	S450	EPSD\|PSP	BRF1 BRF GTF3B TAF3B2 TAF3C	CIssQssDPKDAsGDGELDLsGIDDLEIDRYILNESEARVK
Q92994	T270	PSP	BRF1 BRF GTF3B TAF3B2 TAF3C	ISVVKVCESTLRKRLTEFEDtPTSQLTIDEFMKIDLEEECD
Q96A49	S313	Sugiyama	SYAP1 PRO3113	EMEQLVLDKKQEEtAVLEEDsADWEKELQQELQEyEVVtES
Q96A49	T306	Sugiyama	SYAP1 PRO3113	NQEDLRKEMEQLVLDKKQEEtAVLEEDsADWEKELQQELQE
Q96AC1	S666	Sugiyama	FERMT2 KIND2 MIG2 PLEKHC1	VHEFIGGYIFLSTRAKDQNEsLDEEMFyKLTSGWV______
Q96BK5	S110	SIGNOR\|EPSD\|PSP	PINX1 LPTL LPTS	ELNTCHGQETTDSSDKKEKKsFSLEEKsKISKNRVHYMKFT
Q96BK5	S117	SIGNOR\|EPSD\|PSP	PINX1 LPTL LPTS	QETTDSSDKKEKKsFSLEEKsKISKNRVHYMKFTKGKDLSS
Q96BK5	S226	SIGNOR\|EPSD\|PSP	PINX1 LPTL LPTS	QVERKRGKKRNKEATGKDVEsyLQPKAKRHTEGKPERAEAQ
Q96BK5	T141	SIGNOR\|EPSD\|PSP	PINX1 LPTL LPTS	KNRVHYMKFTKGKDLSSRSKtDLDCIFGKRQSKKtPEGDAs
Q96BK5	T317	SIGNOR\|EPSD\|PSP	PINX1 LPTL LPTS	RGKKKLQKPVEIAEDATLEEtLVKKKKKKDSK_________
Q96BM9	S150	Sugiyama	ARL8A ARL10B GIE2	NKRDLPGALDEKELIEKMNLsAIQDREICCYSISCKEKDNI
Q96CT7	S122	Sugiyama	CCDC124	DtLRRDHQLREAPDTAEKAKsHLEVPLEENVNRRVLEEGsV
Q96CV9	S177	SIGNOR\|EPSD\|PSP\|Sugiyama	OPTN FIP2 GLC1E HIP7 HYPL NRP	LLGIVSELQLKLNssGssEDsFVEIRMAEGEAEGsVKEIKH
Q96FC3	S204	GPS6	TPX2	IRKYQGLEIKSSDQPLTVPVsPKFSTRFHC___________
Q96FF9	T115	PSP	CDCA5	RELTKEDLFKtHsVPAtPtstPVPNPEAEsssKEGELDARD
Q96FF9	T151	SIGNOR\|PSP	CDCA5	LDARDLEMsKKVRRsYsRLEtLGsAststPGRRsCFGFEGL
Q96GD4	T236	PSP	AURKB AIK2 AIM1 AIRK2 ARK2 STK1 STK12 STK5	IADFGWSVHAPsLRRKtMCGtLDYLPPEMIEGRMHNEKVDL
Q96HE7	S143	Sugiyama	ERO1A ERO1L UNQ434/PRO865	EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q96HE7	T148	Sugiyama	ERO1A ERO1L UNQ434/PRO865	IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA
Q96T23	S1359	SIGNOR\|EPSD\|PSP	RSF1 HBXAP XAP8	KPyRIEsDEEEDFENVGKVGsPLDysLVDLPstNGQsPGKA
Q99497	S57	Sugiyama	PARK7	GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL
Q99613	S865	Sugiyama	EIF3C EIF3S8	HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99614	S90	Sugiyama	TTC1 TPR1	FEEEPGADKVENKsNEDVNssELDEEyLIELEKNMSDEEKQ
Q99615	S94	Sugiyama	DNAJC7 TPR2 TTC2	MLGRFREALGDAQQsVRLDDsFVRGHLREGKCHLSLGNAMA
Q99640	S426	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	PKMYT1 MYT1	PLGPPAtPPGsPPCSLLLDSsLSSNWDDDSLGPSLsPEAVL
Q99640	T495	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	PKMYT1 MYT1	PPRGsFPsFEPRNLLSLFEDtLDPT________________
Q99661	S621	SIGNOR\|PSP	KIF2C KNSL6	QMETEEMEACSNGALIPGNLsKEEEELssQMssFNEAMTQI
Q99661	S632	SIGNOR\|PSP	KIF2C KNSL6	NGALIPGNLsKEEEELssQMssFNEAMTQIRELEEKAMEEL
Q99661	S633	SIGNOR\|PSP	KIF2C KNSL6	GALIPGNLsKEEEELssQMssFNEAMTQIRELEEKAMEELK
Q99661	S715	SIGNOR\|EPSD\|PSP	KIF2C KNSL6	SALRDVIKALRLAMQLEEQAsRQISSKKRPQ__________
Q99708	S723	PSP	RBBP8 CTIP	MKKQEQKGEKSSNEERKMNDsLEDMFDRtTHEEYESCLADS
Q99708	T693	PSP	RBBP8 CTIP	IDTKDGSQSKLGGETVDMDCtLVSETVLLKMKKQEQKGEKS
Q99708	T731	PSP	RBBP8 CTIP	EKSSNEERKMNDsLEDMFDRtTHEEYESCLADSFsQAADEE
Q99741	T37	SIGNOR\|EPSD\|PSP	CDC6 CDC18L	RKLSRALNKAKNSSDAKLEPtNVQTVtCsPRVKALPLsPRK
Q99832	T351	Sugiyama	CCT7 CCTH NIP7-1	QtSVNALSADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCt
Q9BQE3	S439	Sugiyama	TUBA1C TUBA6	SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BQE3	S48	Sugiyama	TUBA1C TUBA6	HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3	T41	Sugiyama	TUBA1C TUBA6	WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q9BQE3	T51	Sugiyama	TUBA1C TUBA6	QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q9BQE3	T73	Sugiyama	TUBA1C TUBA6	FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3	T80	Sugiyama	TUBA1C TUBA6	KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQQ3	S189	EPSD\|PSP	GORASP1 GOLPH5 GRASP65	KSDSCREVTVTPNAAWGGEGsLGCGIGYGYLHRIPTQPPSY
Q9BRS2	T128	Sugiyama	RIOK1 RIO1	PADKVLRKFENKINLDKLNVtDsVINKVTEKSRQKEADMYR
Q9BVS4	S335	SIGNOR\|EPSD\|PSP\|Sugiyama	RIOK2 RIO2	LLHPLGPDDKNIETKEGsEFsFsDGEVAEKAEVyGsENEsE
Q9BVS4	S380	SIGNOR\|EPSD\|PSP	RIOK2 RIO2	EEsEGCYCRssGDPEQIKEDsLsEEsADARsFEMTEFNQAL
Q9BVS4	S412	Sugiyama	RIOK2 RIO2	EMTEFNQALEEIKGQVVENNsVTEFsEEKNRTENYNRQDGQ
Q9BVS4	S548	SIGNOR\|EPSD\|PSP	RIOK2 RIO2	IFTKQRRENMQNIKssLEAAsFWGE________________
Q9BXJ9	S855	Sugiyama	NAA15 GA19 NARG1 NATH TBDN100	ALAFMPPGYEEDMKItVNGDssAEAEELANEI_________
Q9BY44	S526	Sugiyama	EIF2A CDA02 MSTP004 MSTP089	sPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKLKA
Q9BYX7	S239	Sugiyama	POTEKP ACTBL3 FKSG30	VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9BYX7	S365	Sugiyama	POTEKP ACTBL3 FKSG30	ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q9BYX7	S368	Sugiyama	POTEKP ACTBL3 FKSG30	SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BZI7	S166	Sugiyama	UPF3B RENT3B UPF3X	KRDTKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIE
Q9C0C2	S1046	Sugiyama	TNKS1BP1 KIAA1741 TAB182	GLFsPstAHVPDGALGQRDQssWQNsDAsQEVGGHQERQQA
Q9C0C2	S1173	Sugiyama	TNKS1BP1 KIAA1741 TAB182	KttAGsVDWTDQLGLRNLEVssCVGsGGssEAREsAVGQMG
Q9C0C2	S1371	Sugiyama	TNKS1BP1 KIAA1741 TAB182	QNVELFGAPSEAREHGVGGVsQCPEPGLRHNGsLsPGLEAR
Q9C0C2	S936	Sugiyama	TNKS1BP1 KIAA1741 TAB182	GRyssQDADEQDWEFQKRDVsLGTyGSRAAEPQEQEFGKSA
Q9C0C2	T1323	Sugiyama	TNKS1BP1 KIAA1741 TAB182	ELGVGQMDWGNNLGLRDLEVtCDPDsGGsQGLRGCGVGQMD
Q9H0D6	S499	Sugiyama	XRN2	sFtsDGsPsPLGGIKRKAEDsDsEPEPEDNVRLWEAGWKQR
Q9H0H5	S149	GPS6\|EPSD\|PSP	RACGAP1 KIAA1478 MGCRACGAP	NRGQPSSSNAGNKRLstIDEsGsILsDIsFDKtDEsLDWDs
Q9H0H5	S157	GPS6\|SIGNOR\|EPSD\|PSP	RACGAP1 KIAA1478 MGCRACGAP	NAGNKRLstIDEsGsILsDIsFDKtDEsLDWDssLVKTFKL
Q9H0H5	S164	GPS6\|EPSD\|PSP	RACGAP1 KIAA1478 MGCRACGAP	stIDEsGsILsDIsFDKtDEsLDWDssLVKTFKLKKREKRR
Q9H0H5	S170	GPS6\|SIGNOR\|EPSD\|PSP	RACGAP1 KIAA1478 MGCRACGAP	GsILsDIsFDKtDEsLDWDssLVKTFKLKKREKRRstsRQF
Q9H0H5	S214	SIGNOR\|EPSD\|PSP	RACGAP1 KIAA1478 MGCRACGAP	PPGPVKKtRsIGsAVDQGNEsIVAKTTVTVPNDGGPIEAVS
Q9H0H5	T260	SIGNOR\|EPSD\|PSP	RACGAP1 KIAA1478 MGCRACGAP	PYWtRSRRKtGtLQPWNsDstLNSRQLEPRTETDsVGtPQs
Q9H1A4	S355	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	ANAPC1 TSG24	PsLHsRsPsISNMAALsRAHsPALGVHsFsGVQRFNIssHN
Q9H1A4	S373	EPSD\|PSP	ANAPC1 TSG24	AHsPALGVHsFsGVQRFNIssHNQsPKRHSISHSPNSNSNG
Q9H1A4	S377	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	ANAPC1 TSG24	ALGVHsFsGVQRFNIssHNQsPKRHSISHSPNSNSNGSFLA
Q9H1A4	S547	EPSD\|PSP	ANAPC1 TSG24	RPstPLDGVstPKPLSKLLGsLDEVVLLsPVPELRDssKLH
Q9H1A4	S686	GPS6\|ELM\|iPTMNet\|EPSD	ANAPC1 TSG24	NMMGYNTDRLAWTRNFDFEGsLsPVIAPKKARPsEtGsDDD
Q9H1A4	S688	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	ANAPC1 TSG24	MGYNTDRLAWTRNFDFEGsLsPVIAPKKARPsEtGsDDDWE
Q9H1A4	T291	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	ANAPC1 TSG24	LRRVKSEEENVVLKFsEQGGtPQNVAtsssLTAHLRsLsKG
Q9H1A4	T520	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	ANAPC1 TSG24	YTGVVRVGKVFIPGLPAPsLtMsNtMPRPstPLDGVstPKP
Q9H1A4	T530	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	ANAPC1 TSG24	FIPGLPAPsLtMsNtMPRPstPLDGVstPKPLSKLLGsLDE
Q9H1A4	T701	EPSD\|PSP	ANAPC1 TSG24	FDFEGsLsPVIAPKKARPsEtGsDDDWEYLLNSDYHQNVES
Q9H2D6	T2229	SIGNOR	TRIOBP KIAA1662 TARA HRIHFB2122	YSQKCLEIGALMRQAEEREHtLRRCQQEGQELLRHNQELHG
Q9H2D6	T447	SIGNOR	TRIOBP KIAA1662 TARA HRIHFB2122	NPRTSCAQRDNPRASSPSRAtRDNPTTSCAQRDNPRASRTS
Q9H2G2	S344	Sugiyama	SLK KIAA0204 STK2	EEEtENsLPIPAsKRAssDLsIAssEEDKLsQNACILEsVS
Q9H6R7	S686	SIGNOR\|PSP	WDCP C2orf44 PP384	ATQEIIIRDGSLSRSDVFRDsFsHsPGAVsSLKVFTGLAAP
Q9H6R7	S695	SIGNOR\|PSP	WDCP C2orf44 PP384	GSLSRSDVFRDsFsHsPGAVsSLKVFTGLAAPSLDTTGCCN
Q9HAW4	S30	SIGNOR\|EPSD\|PSP	CLSPN	HLEINDPNVISQEEADSPSDsGQGsYETIGPLSEGDSDEEI
Q9HBU6	T109	Sugiyama	ETNK1 EKI1	AMANYIHVPPGSPEVPKLNVtVQDQEEHRCREGALSLLQHL
Q9NQ48	S209	Sugiyama	LZTFL1	LQDLQLDQGNQKDFIKAQDLsNLENtVAALKSEFQKTLNDK
Q9NQ48	T214	Sugiyama	LZTFL1	LDQGNQKDFIKAQDLsNLENtVAALKSEFQKTLNDKTENQK
Q9NQP4	T16	Sugiyama	PFDN4 PFD4	_____MAATMKKAAAEDVNVtFEDQQKINKFARNTSRITEL
Q9NRF8	S574	Sugiyama	CTPS2	YLQQGCKLsssDRysDAsDDsFSEPRIAELEIS________
Q9NRX4	T119	Sugiyama	PHPT1 PHP14 CGI-202 HSPC141	PAQHAISTEKIKAKyPDyEVtWANDGy______________
Q9NS56	S718	GPS6\|SIGNOR\|EPSD\|PSP	TOPORS LUN TP53BPL	SRYKWEYTYYSRNKDRDGYEsSYRRRTLSRAHYSRQsssPE
Q9NSB2	S178	Sugiyama	KRT84 KRTHB4	AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NSG2	S43	PSP	FIRRM APOLO1 C1orf112	TVKLFDDMMYELTSQARGLssQNLEIQTTLRNILQTMVQLL
Q9NSG2	S744	PSP	FIRRM APOLO1 C1orf112	NHEEIVPQCLSSEETKNKVVsFLEKTGFVDETEAAKVERVK
Q9NVJ2	S150	Sugiyama	ARL8B ARL10C GIE1	NKRDLPNALDEKQLIEKMNLsAIQDREICCYSISCKEKDNI
Q9NVR5	S773	Sugiyama	DNAAF2 C14orf104 KTU	EFIKEKSATCSNEEKDNLNEsVITEEKETDGDHLsSLLNKT
Q9NYZ3	S223	EPSD	GTSE1	PGPPHSAHALPRESCTAHAAsQAATQRKPGTKLLLPRAASV
Q9NZB2	T413	Sugiyama	FAM120A C9orf10 KIAA0183 OSSA	yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER
Q9UBB4	S77	SIGNOR\|EPSD\|PSP	ATXN10 SCA10	SSHAVELACRDPSQVENLASsLQLItECFRCLRNACIECSV
Q9UBB4	T82	SIGNOR\|EPSD\|PSP	ATXN10 SCA10	ELACRDPSQVENLASsLQLItECFRCLRNACIECSVNQNSI
Q9UBW7	S303	SIGNOR\|EPSD\|PSP	ZMYM2 FIM RAMP ZNF198	DSWISQSASFPRNQKQPGVDsLsPVAsLPKQIFQPSVQQQP
Q9UBW7	S305	SIGNOR\|EPSD\|PSP	ZMYM2 FIM RAMP ZNF198	WISQSASFPRNQKQPGVDsLsPVAsLPKQIFQPSVQQQPTK
Q9UBW7	S309	SIGNOR\|EPSD\|PSP	ZMYM2 FIM RAMP ZNF198	SASFPRNQKQPGVDsLsPVAsLPKQIFQPSVQQQPTKPVKV
Q9UJX2	T562	GPS6\|EPSD\|PSP	CDC23 ANAPC8	tREEGKALLRQILQLRNQGEtPttEVPAPFFLPAsLsANNt
Q9UJX2	T565	EPSD\|PSP	CDC23 ANAPC8	EGKALLRQILQLRNQGEtPttEVPAPFFLPAsLsANNtPtR
Q9UJX3	S17	ELM\|PSP	ANAPC7 APC7	____MNVIDHVRDMAAAGLHsNVRLLsSLLLTMsNNNPELF
Q9UJX3	S23	ELM\|PSP	ANAPC7 APC7	VIDHVRDMAAAGLHsNVRLLsSLLLTMsNNNPELFSPPQKY
Q9UJX3	S30	ELM\|PSP	ANAPC7 APC7	MAAAGLHsNVRLLsSLLLTMsNNNPELFSPPQKYQLLVYHA
Q9UJX3	S64	GPS6\|EPSD	ANAPC7 APC7	QLLVYHADSLFHDKEYRNAVsKYTMALQQKKALSKTSKVRP
Q9UJX5	S779	GPS6\|ELM\|iPTMNet\|EPSD\|PSP	ANAPC4 APC4	DEEEEASNKPVKIKEEVLsEsEAENQQAGAAALAPEIVIKV
Q9UK45	S16	Sugiyama	LSM7	_____MADKEKKKKEsILDLsKYIDKTIRVKFQGGREASGI
Q9UKT4	S145	EPSD\|PSP	FBXO5 EMI1 FBX5	QTLNSTNEIEALETSRLyEDsGYSsFSLQSGLSEHEEGSLL
Q9UKT4	S149	EPSD\|PSP	FBXO5 EMI1 FBX5	STNEIEALETSRLyEDsGYSsFSLQSGLSEHEEGSLLEENF
Q9UNF0	S273	Sugiyama	PACSIN2	KHLDLSNVAGYKAIyHDLEQsIRAADAVEDLRWFRANHGPG
Q9UPQ0	S201	Sugiyama	LIMCH1 KIAA1102	DCWDsERsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVV
Q9UQ80	T200	Sugiyama	PA2G4 EBP1	TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV
Q9UQ80	T386	Sugiyama	PA2G4 EBP1	tQKKKKKKAsKtAENAtsGEtLEENEAGD____________
Q9UQE7	S886	Sugiyama	SMC3 BAM BMH CSPG6 SMC3L1	LEAINKRVKDTMARSEDLDNsIDKTEAGIKELQKSMERWKN
Q9Y265	S29	Sugiyama	RUVBL1 INO80H NMP238 TIP49 TIP49A	TTKTQRIAsHSHVKGLGLDEsGLAKQAASGLVGQENAREAC
Q9Y265	T239	EPSD\|PSP	RUVBL1 INO80H NMP238 TIP49 TIP49A	EyVPLPKGDVHKKKEIIQDVtLHDLDVANARPQGGQDILSM
Q9Y266	S274	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NUDC	WSRLVssDPEINtKKINPENsKLsDLDsEtRsMVEKMMYDQ
Q9Y266	S326	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NUDC	EQKKQEILKKFMDQHPEMDFsKAKFN_______________
Q9Y266	T145	Sugiyama	NUDC	AENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKLKPNLGN
Q9Y2B0	S116	Sugiyama	CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426	IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA
Q9Y2B0	S178	Sugiyama	CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426	NVKDKLCSKRtDLCDHALHIsHDEL________________
Q9Y2B0	S63	Sugiyama	CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426	AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2I6	S686	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NINL KIAA0980 NLP	RREVSVLEGQKADLEELHEKsQEVIWGLQEQLQDTARGPEP
Q9Y2I6	S87	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NINL KIAA0980 NLP	KEGFVAVLSSNAGVRPSDEDssSLESAASSAIPPKYVNGSK
Q9Y2I6	S88	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NINL KIAA0980 NLP	EGFVAVLSSNAGVRPSDEDssSLESAASSAIPPKYVNGSKW
Q9Y2I6	T161	GPS6\|SIGNOR\|ELM\|iPTMNet\|EPSD\|PSP	NINL KIAA0980 NLP	WRSASLESVESPKSDEEAEStKEAQNELFEAQGQLQTWDSE
Q9Y2L5	S377	Sugiyama	TRAPPC8 KIAA1012	FRGLLPHIEKTIRQLNDQLIsRKGLSRSLFSATKKWFSGSK
Q9Y2R5	S128	Sugiyama	MRPS17 RPMS17 HSPC011	SPLSSETTQLSKNLEELNIssAQ__________________
Q9Y2T1	S311	SIGNOR\|EPSD\|PSP	AXIN2	FAPATSANDSEISSDALTDDsMSMTDSSVDGIPPYRVGSKK
Q9Y2Z0	S331	SIGNOR\|EPSD\|PSP	SUGT1	RLFQQIysDGsDEVKRAMNKsFMESGGTVLSTNWSDVGKRK
Q9Y394	S329	Sugiyama	DHRS7 DHRS7A RETSDR4 SDR34C1 CGI-86 UNQ285/PRO3448	TNKMGKKRIENFKSGVDADssyFKIFKTKHD__________
Q9Y3U8	S91	Sugiyama	RPL36	KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y5S9	S56	Sugiyama	RBM8A RBM8 HSPC114 MDS014	KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y5T5	S330	SIGNOR\|EPSD\|PSP	USP16 MSTP039	GMRAEEHQRVSKGILKAFGNsTEKLDEELKNKVKDYEKKKS
Q9Y5T5	S386	SIGNOR\|EPSD\|PSP	USP16 MSTP039	MIMCDQCRTVSLVHESFLDLsLPVLDDQSGKKSVNDKNLKK
Q9Y5T5	S486	SIGNOR\|EPSD\|PSP	USP16 MSTP039	HLNDICTIDHPEDSEYEAEMsLQGEVNIKSNHISQEGVMHK
Q9Y6D9	S22	EPSD\|PSP	MAD1L1 MAD1 TXBP181	EDLGENtMVLSTLRsLNNFIsQRVEGGsGLDISTSAPGSLQ
Q9Y6D9	S29	EPSD\|PSP	MAD1L1 MAD1 TXBP181	MVLSTLRsLNNFIsQRVEGGsGLDISTSAPGSLQMQYQQSM
Q9Y6D9	T680	SIGNOR\|EPSD\|PSP	MAD1L1 MAD1 TXBP181	GDCLIFKATSPSGSKMQLLEtEFSHTVGELIEVHLRRQDsI

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

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name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Cell Cycle	R-HSA-1640170	1.345590e-13	12.871	1	0
Mitotic Prometaphase	R-HSA-68877	1.831901e-11	10.737	1	1
Cell Cycle, Mitotic	R-HSA-69278	1.709483e-10	9.767	1	0
M Phase	R-HSA-68886	1.255827e-09	8.901	1	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	5.205833e-09	8.284	1	1
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	2.055964e-08	7.687	0	0
Apoptotic cleavage of cellular proteins	R-HSA-111465	8.945470e-08	7.048	0	0
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	1.778982e-07	6.750	1	1
Mitotic Anaphase	R-HSA-68882	1.790369e-07	6.747	1	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	2.077256e-07	6.683	1	0
Cell Cycle Checkpoints	R-HSA-69620	2.615742e-07	6.582	1	0
Membrane Trafficking	R-HSA-199991	4.897477e-07	6.310	0	0
Separation of Sister Chromatids	R-HSA-2467813	6.362831e-07	6.196	1	1
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	7.312987e-07	6.136	0	0
Signaling by ALK in cancer	R-HSA-9700206	7.312987e-07	6.136	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	8.521187e-07	6.069	1	1
Amplification of signal from the kinetochores	R-HSA-141424	8.521187e-07	6.069	1	0
Mitotic Spindle Checkpoint	R-HSA-69618	8.471363e-07	6.072	1	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	2.026865e-06	5.693	0	0
Apoptotic execution phase	R-HSA-75153	2.457806e-06	5.609	0	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	6.468780e-06	5.189	0	0
Regulation of TP53 Activity	R-HSA-5633007	6.727963e-06	5.172	0	0
Axon guidance	R-HSA-422475	2.399914e-05	4.620	0	0
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	2.594289e-05	4.586	1	1
Signaling by Hippo	R-HSA-2028269	2.947966e-05	4.530	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	3.658732e-05	4.437	1	1
Regulation of localization of FOXO transcription factors	R-HSA-9614399	5.172649e-05	4.286	0	0
AURKA Activation by TPX2	R-HSA-8854518	5.247307e-05	4.280	1	1
VEGFA-VEGFR2 Pathway	R-HSA-4420097	5.366843e-05	4.270	0	0
Centrosome maturation	R-HSA-380287	5.517532e-05	4.258	1	0
L1CAM interactions	R-HSA-373760	6.274723e-05	4.202	0	0
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	6.988744e-05	4.156	1	1
Loss of Nlp from mitotic centrosomes	R-HSA-380259	6.988744e-05	4.156	1	1
Transcriptional Regulation by E2F6	R-HSA-8953750	6.796857e-05	4.168	0	0
Apoptosis	R-HSA-109581	6.932989e-05	4.159	0	0
Recycling pathway of L1	R-HSA-437239	8.648831e-05	4.063	0	0
Nervous system development	R-HSA-9675108	9.641594e-05	4.016	0	0
Signal Transduction	R-HSA-162582	1.246395e-04	3.904	1	0
Cohesin Loading onto Chromatin	R-HSA-2470946	1.336127e-04	3.874	0	0
Signaling by VEGF	R-HSA-194138	1.343414e-04	3.872	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	1.402882e-04	3.853	0	0
Signaling by RAS mutants	R-HSA-6802949	1.860125e-04	3.730	0	0
Signaling downstream of RAS mutants	R-HSA-9649948	1.860125e-04	3.730	0	0
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	1.860125e-04	3.730	0	0
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	1.860125e-04	3.730	0	0
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	1.940696e-04	3.712	1	1
G2/M Transition	R-HSA-69275	2.176557e-04	3.662	1	0
Signaling by ERBB2	R-HSA-1227986	2.337887e-04	3.631	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	2.450172e-04	3.611	0	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	2.601887e-04	3.585	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	2.698283e-04	3.569	0	0
Mitotic G2-G2/M phases	R-HSA-453274	2.711367e-04	3.567	1	0
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	2.902403e-04	3.537	1	1
mRNA Splicing - Major Pathway	R-HSA-72163	2.929122e-04	3.533	0	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	3.816693e-04	3.418	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	3.866683e-04	3.413	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	3.866683e-04	3.413	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	3.866683e-04	3.413	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	3.866683e-04	3.413	0	0
Signaling by RAF1 mutants	R-HSA-9656223	4.170449e-04	3.380	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	4.280036e-04	3.369	1	1
Transcriptional Regulation by TP53	R-HSA-3700989	4.304198e-04	3.366	0	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	4.562314e-04	3.341	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	5.143275e-04	3.289	0	0
Kinesins	R-HSA-983189	5.637960e-04	3.249	0	0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways	R-HSA-9755779	5.765507e-04	3.239	0	0
G2/M DNA damage checkpoint	R-HSA-69473	5.789278e-04	3.237	0	0
Metabolism of RNA	R-HSA-8953854	6.069858e-04	3.217	0	0
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	7.137861e-04	3.146	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	7.503391e-04	3.125	0	0
Oncogenic MAPK signaling	R-HSA-6802957	7.371040e-04	3.132	0	0
Nuclear Envelope Breakdown	R-HSA-2980766	7.549017e-04	3.122	1	0
ATP-dependent chromatin remodelers	R-HSA-9932444	7.829487e-04	3.106	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	7.829487e-04	3.106	0	0
mRNA Splicing	R-HSA-72172	8.840779e-04	3.054	0	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	9.213796e-04	3.036	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	9.975045e-04	3.001	0	0
Gene expression (Transcription)	R-HSA-74160	1.022161e-03	2.990	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	1.024440e-03	2.990	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	1.006432e-03	2.997	0	0
Activation of BH3-only proteins	R-HSA-114452	1.024851e-03	2.989	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	1.049211e-03	2.979	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	1.075001e-03	2.969	0	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	1.178847e-03	2.929	0	0
Post NMDA receptor activation events	R-HSA-438064	1.158489e-03	2.936	0	0
MITF-M-regulated melanocyte development	R-HSA-9730414	1.224734e-03	2.912	1	0
Selective autophagy	R-HSA-9663891	1.339115e-03	2.873	0	0
Regulation of TP53 Expression and Degradation	R-HSA-6806003	1.468838e-03	2.833	0	0
Regulation of KIT signaling	R-HSA-1433559	1.509938e-03	2.821	0	0
Chromatin organization	R-HSA-4839726	1.540345e-03	2.812	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	1.653597e-03	2.782	0	0
Signaling by SCF-KIT	R-HSA-1433557	1.658067e-03	2.780	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	1.718021e-03	2.765	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	1.816592e-03	2.741	0	0
Regulation of TP53 Degradation	R-HSA-6804757	1.974384e-03	2.705	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	2.164971e-03	2.665	0	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	2.117309e-03	2.674	0	0
Semaphorin interactions	R-HSA-373755	2.163725e-03	2.665	0	0
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	2.123899e-03	2.673	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	2.164971e-03	2.665	0	0
Autophagy	R-HSA-9612973	2.240165e-03	2.650	0	0
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	2.254065e-03	2.647	0	0
Macroautophagy	R-HSA-1632852	2.263581e-03	2.645	0	0
Ephrin signaling	R-HSA-3928664	2.337849e-03	2.631	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	2.349053e-03	2.629	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	2.445264e-03	2.612	0	0
Golgi-to-ER retrograde transport	R-HSA-8856688	2.423116e-03	2.616	0	0
Metabolism of non-coding RNA	R-HSA-194441	2.452450e-03	2.610	0	0
snRNP Assembly	R-HSA-191859	2.452450e-03	2.610	0	0
Programmed Cell Death	R-HSA-5357801	2.600992e-03	2.585	0	0
EPH-Ephrin signaling	R-HSA-2682334	2.652507e-03	2.576	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	2.855584e-03	2.544	0	0
Vesicle-mediated transport	R-HSA-5653656	2.951141e-03	2.530	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	3.279090e-03	2.484	0	0
Cellular response to heat stress	R-HSA-3371556	3.315060e-03	2.480	0	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	3.279079e-03	2.484	0	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	3.667246e-03	2.436	0	0
Regulation of CDH1 Function	R-HSA-9764561	3.856669e-03	2.414	0	0
NrCAM interactions	R-HSA-447038	3.878095e-03	2.411	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	3.996093e-03	2.398	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	4.174549e-03	2.379	0	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	4.174549e-03	2.379	0	0
Nephrin family interactions	R-HSA-373753	4.174549e-03	2.379	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	4.443741e-03	2.352	0	0
Aggrephagy	R-HSA-9646399	4.443741e-03	2.352	0	0
Cell-Cell communication	R-HSA-1500931	4.718772e-03	2.326	0	0
Cellular responses to stress	R-HSA-2262752	4.414327e-03	2.355	0	0
Cellular responses to stimuli	R-HSA-8953897	4.512242e-03	2.346	0	0
RUNX2 regulates genes involved in cell migration	R-HSA-8941332	4.873312e-03	2.312	0	0
PECAM1 interactions	R-HSA-210990	4.873312e-03	2.312	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	4.931798e-03	2.307	0	0
Formation of tubulin folding intermediates by CCT/TriC	R-HSA-389960	5.182324e-03	2.285	0	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	5.411097e-03	2.267	0	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	5.483621e-03	2.261	0	0
Formation of annular gap junctions	R-HSA-196025	5.921142e-03	2.228	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	5.921142e-03	2.228	0	0
Sema4D in semaphorin signaling	R-HSA-400685	6.543368e-03	2.184	0	0
Impaired BRCA2 binding to RAD51	R-HSA-9709570	6.023595e-03	2.220	0	0
MAP2K and MAPK activation	R-HSA-5674135	6.397694e-03	2.194	0	0
Long-term potentiation	R-HSA-9620244	6.543368e-03	2.184	0	0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	R-HSA-8950505	6.152205e-03	2.211	0	0
Resolution of D-Loop Structures	R-HSA-5693537	6.698455e-03	2.174	0	0
RUNX1 regulates expression of components of tight junctions	R-HSA-8935964	6.725049e-03	2.172	0	0
G2/M Checkpoints	R-HSA-69481	6.823058e-03	2.166	0	0
Signaling by EGFR	R-HSA-177929	7.014298e-03	2.154	0	0
DCC mediated attractive signaling	R-HSA-418885	7.367789e-03	2.133	0	0
Cell-extracellular matrix interactions	R-HSA-446353	7.367789e-03	2.133	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	7.430030e-03	2.129	0	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	7.430030e-03	2.129	0	0
mRNA 3'-end processing	R-HSA-72187	8.043806e-03	2.095	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	8.853543e-03	2.053	0	0
Gap junction degradation	R-HSA-190873	8.853543e-03	2.053	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	8.117591e-03	2.091	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	8.117591e-03	2.091	0	0
Myogenesis	R-HSA-525793	8.169488e-03	2.088	0	0
Nuclear import of Rev protein	R-HSA-180746	8.117591e-03	2.091	0	0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	R-HSA-389958	9.082083e-03	2.042	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	9.082083e-03	2.042	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	9.082083e-03	2.042	0	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	9.261528e-03	2.033	0	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	9.629814e-03	2.016	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	9.763296e-03	2.010	0	0
EPHA-mediated growth cone collapse	R-HSA-3928663	1.009283e-02	1.996	0	0
Signaling by TGF-beta Receptor Complex in Cancer	R-HSA-3304351	1.078427e-02	1.967	0	0
EPHB-mediated forward signaling	R-HSA-3928662	1.056363e-02	1.976	0	0
Cilium Assembly	R-HSA-5617833	1.084999e-02	1.965	1	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	1.111002e-02	1.954	0	0
Prefoldin mediated transfer of substrate to CCT/TriC	R-HSA-389957	1.111002e-02	1.954	0	0
PKR-mediated signaling	R-HSA-9833482	1.138707e-02	1.944	0	0
RET signaling	R-HSA-8853659	1.165848e-02	1.933	0	0
ISG15 antiviral mechanism	R-HSA-1169408	1.169051e-02	1.932	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	1.183656e-02	1.927	0	0
AKT-mediated inactivation of FOXO1A	R-HSA-211163	1.199400e-02	1.921	0	0
Co-inhibition by CTLA4	R-HSA-389513	1.206133e-02	1.919	0	0
PKMTs methylate histone lysines	R-HSA-3214841	1.209237e-02	1.917	0	0
Cellular Senescence	R-HSA-2559583	1.209531e-02	1.917	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	1.234629e-02	1.908	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	1.235736e-02	1.908	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	1.316132e-02	1.881	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	1.316132e-02	1.881	0	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	1.323134e-02	1.878	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	1.323134e-02	1.878	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	1.323134e-02	1.878	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	1.409908e-02	1.851	0	0
Ion homeostasis	R-HSA-5578775	1.428640e-02	1.845	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	1.270136e-02	1.896	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	1.418682e-02	1.848	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	1.383770e-02	1.859	0	0
Interleukin-12 signaling	R-HSA-9020591	1.317381e-02	1.880	0	0
Chromatin modifying enzymes	R-HSA-3247509	1.469768e-02	1.833	0	0
RNA Polymerase II Transcription	R-HSA-73857	1.473416e-02	1.832	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	1.496309e-02	1.825	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	1.496309e-02	1.825	0	0
Mitotic Prophase	R-HSA-68875	1.509634e-02	1.821	1	0
MITF-M-dependent gene expression	R-HSA-9856651	1.548841e-02	1.810	1	0
COPI-mediated anterograde transport	R-HSA-6807878	1.576635e-02	1.802	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	1.578378e-02	1.802	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	1.578378e-02	1.802	0	0
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	1.578378e-02	1.802	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	1.626041e-02	1.789	0	0
IFNG signaling activates MAPKs	R-HSA-9732724	1.626041e-02	1.789	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	1.629098e-02	1.788	0	0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	R-HSA-190840	1.644718e-02	1.784	0	0
RAF activation	R-HSA-5673000	1.869173e-02	1.728	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	1.658673e-02	1.780	0	0
HIV Life Cycle	R-HSA-162587	1.714438e-02	1.766	0	0
Signaling by PDGFR in disease	R-HSA-9671555	1.880289e-02	1.726	0	0
Initiation of Nuclear Envelope (NE) Reformation	R-HSA-2995383	1.880289e-02	1.726	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	1.907547e-02	1.720	0	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	1.920257e-02	1.717	0	0
RUNX1 regulates transcription of genes involved in BCR signaling	R-HSA-8939245	1.986879e-02	1.702	0	0
Loss of Function of TGFBR1 in Cancer	R-HSA-3656534	1.986879e-02	1.702	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	2.040460e-02	1.690	0	0
Ion transport by P-type ATPases	R-HSA-936837	2.049557e-02	1.688	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	2.076221e-02	1.683	0	0
Chaperone Mediated Autophagy	R-HSA-9613829	2.076221e-02	1.683	0	0
Transport of connexons to the plasma membrane	R-HSA-190872	2.076221e-02	1.683	0	0
DNA Repair	R-HSA-73894	2.078876e-02	1.682	0	0
Drug resistance in ERBB2 KD mutants	R-HSA-9665230	2.114720e-02	1.675	0	0
Drug-mediated inhibition of ERBB2 signaling	R-HSA-9652282	2.114720e-02	1.675	0	0
RUNX3 regulates RUNX1-mediated transcription	R-HSA-8951911	2.114720e-02	1.675	0	0
Drug resistance in ERBB2 TMD/JMD mutants	R-HSA-9665737	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to afatinib	R-HSA-9665249	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to osimertinib	R-HSA-9665247	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to neratinib	R-HSA-9665246	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to tesevatinib	R-HSA-9665245	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to lapatinib	R-HSA-9665251	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to trastuzumab	R-HSA-9665233	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to sapitinib	R-HSA-9665244	2.114720e-02	1.675	0	0
Resistance of ERBB2 KD mutants to AEE788	R-HSA-9665250	2.114720e-02	1.675	0	0
Gap junction trafficking and regulation	R-HSA-157858	2.193016e-02	1.659	0	0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	R-HSA-8939246	2.332780e-02	1.632	0	0
Downregulation of ERBB4 signaling	R-HSA-1253288	2.332780e-02	1.632	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	2.449550e-02	1.611	0	0
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	2.545575e-02	1.594	0	0
Nucleosome assembly	R-HSA-774815	2.545575e-02	1.594	0	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	2.304441e-02	1.637	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	2.198255e-02	1.658	0	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	2.445834e-02	1.612	0	0
Signalling to ERKs	R-HSA-187687	2.198255e-02	1.658	0	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	2.198255e-02	1.658	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	2.490631e-02	1.604	0	0
IRE1alpha activates chaperones	R-HSA-381070	2.560117e-02	1.592	0	0
FLT3 Signaling	R-HSA-9607240	2.569747e-02	1.590	0	0
Interleukin-12 family signaling	R-HSA-447115	2.686180e-02	1.571	0	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	2.782738e-02	1.556	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	2.792830e-02	1.554	0	0
Prolonged ERK activation events	R-HSA-169893	2.857652e-02	1.544	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	2.891211e-02	1.539	0	0
Diseases of DNA repair	R-HSA-9675135	2.909574e-02	1.536	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	2.971656e-02	1.527	0	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	2.971656e-02	1.527	1	1
Vpr-mediated nuclear import of PICs	R-HSA-180910	2.981850e-02	1.526	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	3.032799e-02	1.518	0	0
Loss of Function of SMAD2/3 in Cancer	R-HSA-3304349	3.032799e-02	1.518	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	3.093950e-02	1.509	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	3.115584e-02	1.506	0	0
MHC class II antigen presentation	R-HSA-2132295	3.121955e-02	1.506	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	3.470523e-02	1.460	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	3.470523e-02	1.460	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	3.470523e-02	1.460	0	0
Defective DNA double strand break response due to BRCA1 loss of function	R-HSA-9663199	3.470523e-02	1.460	0	0
Loss of MECP2 binding ability to 5hmC-DNA	R-HSA-9022534	3.470523e-02	1.460	0	0
Defective DNA double strand break response due to BARD1 loss of function	R-HSA-9699150	3.470523e-02	1.460	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	3.470523e-02	1.460	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	3.470523e-02	1.460	0	0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins	R-HSA-9673766	3.719143e-02	1.430	0	0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	R-HSA-5368598	3.719143e-02	1.430	0	0
Loss of MECP2 binding ability to 5mC-DNA	R-HSA-9022538	3.719143e-02	1.430	0	0
Lipophagy	R-HSA-9613354	3.212378e-02	1.493	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	3.212378e-02	1.493	0	0
ERK/MAPK targets	R-HSA-198753	3.839929e-02	1.416	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	3.349671e-02	1.475	0	0
Striated Muscle Contraction	R-HSA-390522	3.463065e-02	1.461	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	3.310314e-02	1.480	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	3.303132e-02	1.481	0	0
MTOR signalling	R-HSA-165159	3.387217e-02	1.470	0	0
Homology Directed Repair	R-HSA-5693538	3.303132e-02	1.481	0	0
GP1b-IX-V activation signalling	R-HSA-430116	3.212378e-02	1.493	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	3.566255e-02	1.448	0	0
Cellular response to mitochondrial stress	R-HSA-9840373	3.212378e-02	1.493	0	0
Intracellular signaling by second messengers	R-HSA-9006925	3.802306e-02	1.420	0	0
Frs2-mediated activation	R-HSA-170968	3.957397e-02	1.403	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	3.957397e-02	1.403	0	0
HDMs demethylate histones	R-HSA-3214842	3.978749e-02	1.400	0	0
Folding of actin by CCT/TriC	R-HSA-390450	4.274481e-02	1.369	0	0
Signal attenuation	R-HSA-74749	4.274481e-02	1.369	0	0
Organelle biogenesis and maintenance	R-HSA-1852241	4.300117e-02	1.367	1	0
Signaling by LTK in cancer	R-HSA-9842640	4.349600e-02	1.362	0	0
Nef and signal transduction	R-HSA-164944	4.349600e-02	1.362	0	0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	R-HSA-8869496	4.349600e-02	1.362	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	4.376389e-02	1.359	0	0
Gap junction trafficking	R-HSA-190828	4.376389e-02	1.359	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	4.382130e-02	1.358	0	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	4.382130e-02	1.358	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	4.494978e-02	1.347	0	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	4.507199e-02	1.346	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	4.600160e-02	1.337	0	0
Listeria monocytogenes entry into host cells	R-HSA-8876384	4.600160e-02	1.337	0	0
Downstream signal transduction	R-HSA-186763	4.677385e-02	1.330	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	4.761899e-02	1.322	0	0
Muscle contraction	R-HSA-397014	4.765346e-02	1.322	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	4.830907e-02	1.316	0	0
Deubiquitination	R-HSA-5688426	4.869231e-02	1.313	0	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	4.939899e-02	1.306	0	0
Ribosomal scanning and start codon recognition	R-HSA-72702	5.076263e-02	1.294	0	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	5.117468e-02	1.291	0	0
Unfolded Protein Response (UPR)	R-HSA-381119	5.306719e-02	1.275	0	0
Depolymerization of the Nuclear Lamina	R-HSA-4419969	5.309400e-02	1.275	0	0
Heme signaling	R-HSA-9707616	5.359977e-02	1.271	0	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	5.393031e-02	1.268	0	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	5.393031e-02	1.268	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	5.466181e-02	1.262	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	5.551435e-02	1.256	0	0
Regulation of gap junction activity	R-HSA-191650	5.791978e-02	1.237	0	0
PLCG1 events in ERBB2 signaling	R-HSA-1251932	5.791978e-02	1.237	0	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	5.791978e-02	1.237	0	0
RUNX2 regulates genes involved in differentiation of myeloid cells	R-HSA-8941333	5.791978e-02	1.237	0	0
TGFBR1 KD Mutants in Cancer	R-HSA-3656532	5.791978e-02	1.237	0	0
Role of ABL in ROBO-SLIT signaling	R-HSA-428890	5.939809e-02	1.226	0	0
Recycling of eIF2:GDP	R-HSA-72731	5.939809e-02	1.226	0	0
Disinhibition of SNARE formation	R-HSA-114516	5.939809e-02	1.226	0	0
ERKs are inactivated	R-HSA-202670	6.963792e-02	1.157	0	0
Signaling by AMER1 mutants	R-HSA-4839748	6.963792e-02	1.157	0	0
Spry regulation of FGF signaling	R-HSA-1295596	6.105089e-02	1.214	0	0
Regulation of signaling by CBL	R-HSA-912631	6.350854e-02	1.197	0	0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	6.241315e-02	1.205	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	6.689263e-02	1.175	0	0
Co-stimulation by CD28	R-HSA-389356	6.923615e-02	1.160	0	0
Golgi Associated Vesicle Biogenesis	R-HSA-432722	6.577458e-02	1.182	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	6.105089e-02	1.214	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	6.350854e-02	1.197	0	0
FLT3 signaling through SRC family kinases	R-HSA-9706374	5.791978e-02	1.237	0	0
Cell junction organization	R-HSA-446728	6.050875e-02	1.218	0	0
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	6.923615e-02	1.160	0	0
Smooth Muscle Contraction	R-HSA-445355	6.577458e-02	1.182	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	6.185616e-02	1.209	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	7.045368e-02	1.152	0	0
SMAD2/3 MH2 Domain Mutants in Cancer	R-HSA-3315487	7.111134e-02	1.148	0	0
SMAD4 MH2 Domain Mutants in Cancer	R-HSA-3311021	7.111134e-02	1.148	0	0
Loss of Function of SMAD4 in Cancer	R-HSA-3304347	7.111134e-02	1.148	0	0
Chaperonin-mediated protein folding	R-HSA-390466	7.246062e-02	1.140	0	0
Translation initiation complex formation	R-HSA-72649	7.278025e-02	1.138	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	7.367719e-02	1.133	0	0
Post-chaperonin tubulin folding pathway	R-HSA-389977	7.507906e-02	1.124	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	7.630446e-02	1.117	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	7.646554e-02	1.117	0	0
Interferon Signaling	R-HSA-913531	7.665941e-02	1.115	0	0
Adrenoceptors	R-HSA-390696	7.797236e-02	1.108	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	7.797236e-02	1.108	0	0
MAPK family signaling cascades	R-HSA-5683057	7.939956e-02	1.100	0	0
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	7.977011e-02	1.098	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	8.028444e-02	1.095	0	0
Netrin-1 signaling	R-HSA-373752	8.109077e-02	1.091	0	0
IRS activation	R-HSA-74713	8.296524e-02	1.081	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	8.296524e-02	1.081	0	0
SMAD2/3 Phosphorylation Motif Mutants in Cancer	R-HSA-3304356	8.296524e-02	1.081	0	0
DAP12 signaling	R-HSA-2424491	8.302142e-02	1.081	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	8.302142e-02	1.081	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	8.338430e-02	1.079	0	0
Generation of second messenger molecules	R-HSA-202433	8.542836e-02	1.068	0	0
VEGFR2 mediated cell proliferation	R-HSA-5218921	8.582927e-02	1.066	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	8.589678e-02	1.066	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	8.772982e-02	1.057	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	8.780594e-02	1.056	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	8.780594e-02	1.056	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	8.826366e-02	1.054	0	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	8.826366e-02	1.054	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	8.826366e-02	1.054	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	8.981025e-02	1.047	0	0
tRNA processing in the nucleus	R-HSA-6784531	9.081792e-02	1.042	0	0
EGFR downregulation	R-HSA-182971	9.412677e-02	1.026	0	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	9.412677e-02	1.026	0	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	9.519499e-02	1.021	0	0
PIP3 activates AKT signaling	R-HSA-1257604	9.573413e-02	1.019	0	0
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	9.598341e-02	1.018	0	0
Signaling by FLT3 fusion proteins	R-HSA-9703465	9.819092e-02	1.008	0	0
Regulation of commissural axon pathfinding by SLIT and ROBO	R-HSA-428542	9.908396e-02	1.004	0	0
ALK mutants bind TKIs	R-HSA-9700645	9.908396e-02	1.004	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	9.947310e-02	1.002	0	0
HIV Infection	R-HSA-162906	1.000864e-01	1.000	0	0
Regulation of TP53 Expression	R-HSA-6804754	1.152682e-01	0.938	0	0
Regulation of cortical dendrite branching	R-HSA-8985801	1.152682e-01	0.938	0	0
TGFBR1 LBD Mutants in Cancer	R-HSA-3656535	1.152682e-01	0.938	0	0
RUNX3 regulates CDKN1A transcription	R-HSA-8941855	1.118144e-01	0.952	0	0
CDH11 homotypic and heterotypic interactions	R-HSA-9833576	1.118144e-01	0.952	0	0
Loss of MECP2 binding ability to the NCoR/SMRT complex	R-HSA-9022537	1.118144e-01	0.952	0	0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation	R-HSA-2151209	1.225400e-01	0.912	0	0
ERBB2 Activates PTK6 Signaling	R-HSA-8847993	1.237354e-01	0.908	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	1.039865e-01	0.983	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	1.039865e-01	0.983	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	1.016761e-01	0.993	0	0
mTORC1-mediated signalling	R-HSA-166208	1.166634e-01	0.933	0	0
Degradation of CDH1	R-HSA-9766229	1.313497e-01	0.882	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	1.149403e-01	0.940	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	1.248045e-01	0.904	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	1.210618e-01	0.917	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	1.210618e-01	0.917	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	1.166634e-01	0.933	0	0
Signal regulatory protein family interactions	R-HSA-391160	1.237354e-01	0.908	0	0
Protein folding	R-HSA-391251	1.123881e-01	0.949	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	1.115022e-01	0.953	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	1.187947e-01	0.925	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	1.060551e-01	0.974	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	1.118144e-01	0.952	0	0
Regulation of CDH11 function	R-HSA-9762292	1.225400e-01	0.912	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	1.265955e-01	0.898	0	0
RAF/MAP kinase cascade	R-HSA-5673001	1.236979e-01	0.908	0	0
Signaling by FGFR4	R-HSA-5654743	1.283213e-01	0.892	0	0
CD28 dependent PI3K/Akt signaling	R-HSA-389357	1.115022e-01	0.953	0	0
Interleukin-6 signaling	R-HSA-1059683	1.039602e-01	0.983	0	0
ER to Golgi Anterograde Transport	R-HSA-199977	1.271554e-01	0.896	0	0
Specification of primordial germ cells	R-HSA-9827857	1.039865e-01	0.983	0	0
Signaling by FGFR4 in disease	R-HSA-5655291	1.237354e-01	0.908	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	1.166484e-01	0.933	0	0
S Phase	R-HSA-69242	1.337021e-01	0.874	0	0
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	1.120556e-01	0.951	0	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	1.045863e-01	0.981	0	0
Death Receptor Signaling	R-HSA-73887	1.323155e-01	0.878	0	0
Adherens junctions interactions	R-HSA-418990	1.167616e-01	0.933	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	1.290909e-01	0.889	0	0
Signaling by NTRKs	R-HSA-166520	1.337021e-01	0.874	0	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	1.016761e-01	0.993	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	1.092756e-01	0.961	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	1.152322e-01	0.938	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	1.137445e-01	0.944	0	0
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	1.225400e-01	0.912	0	0
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	1.166484e-01	0.933	0	0
Signaling by KIT in disease	R-HSA-9669938	1.166634e-01	0.933	0	0
Potential therapeutics for SARS	R-HSA-9679191	1.079431e-01	0.967	0	0
SARS-CoV-2-host interactions	R-HSA-9705683	1.045895e-01	0.981	0	0
Regulation of CDH19 Expression and Function	R-HSA-9764302	1.118144e-01	0.952	0	0
Drug resistance of PDGFR mutants	R-HSA-9674415	1.349314e-01	0.870	0	0
PDGFR mutants bind TKIs	R-HSA-9674428	1.349314e-01	0.870	0	0
Deletions in the AMER1 gene destabilize the destruction complex	R-HSA-5467343	1.349314e-01	0.870	0	0
Imatinib-resistant PDGFR mutants	R-HSA-9674396	1.349314e-01	0.870	0	0
Loss of Function of TP53 in Cancer	R-HSA-9723907	1.349314e-01	0.870	0	0
Loss of function of TP53 in cancer due to loss of tetramerization ability	R-HSA-9723905	1.349314e-01	0.870	0	0
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	1.349314e-01	0.870	0	0
Sunitinib-resistant PDGFR mutants	R-HSA-9674401	1.349314e-01	0.870	0	0
Sorafenib-resistant PDGFR mutants	R-HSA-9674404	1.349314e-01	0.870	0	0
Regorafenib-resistant PDGFR mutants	R-HSA-9674403	1.349314e-01	0.870	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	1.351382e-01	0.869	0	0
Nucleotide Excision Repair	R-HSA-5696398	1.353880e-01	0.868	0	0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes	R-HSA-9856532	1.394233e-01	0.856	0	0
Generic Transcription Pathway	R-HSA-212436	1.401350e-01	0.853	0	0
Late endosomal microautophagy	R-HSA-9615710	1.408778e-01	0.851	0	0
Regulation of gene expression in beta cells	R-HSA-210745	1.408778e-01	0.851	0	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	1.451034e-01	0.838	0	0
p38MAPK events	R-HSA-171007	1.451034e-01	0.838	0	0
ERBB2 Regulates Cell Motility	R-HSA-6785631	1.451034e-01	0.838	0	0
InlB-mediated entry of Listeria monocytogenes into host cell	R-HSA-8875360	1.451034e-01	0.838	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	1.464896e-01	0.834	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	1.468373e-01	0.833	0	0
Signaling by APC mutants	R-HSA-4839744	1.481040e-01	0.829	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	1.481040e-01	0.829	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	1.481040e-01	0.829	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	1.481040e-01	0.829	0	0
Suppression of apoptosis	R-HSA-9635465	1.481040e-01	0.829	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	1.498263e-01	0.824	0	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	1.498263e-01	0.824	0	0
Neurodegenerative Diseases	R-HSA-8863678	1.498263e-01	0.824	0	0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	1.498263e-01	0.824	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	1.498263e-01	0.824	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	1.506825e-01	0.822	0	0
Signaling by FGFR3	R-HSA-5654741	1.534962e-01	0.814	0	0
DAG and IP3 signaling	R-HSA-1489509	1.534962e-01	0.814	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	1.567862e-01	0.805	0	0
RNA Polymerase III Transcription Initiation	R-HSA-76046	1.568741e-01	0.804	0	0
Interleukin-37 signaling	R-HSA-9008059	1.568741e-01	0.804	0	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	1.572173e-01	0.803	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	1.573715e-01	0.803	0	0
Signal transduction by L1	R-HSA-445144	1.589898e-01	0.799	0	0
Negative regulation of MET activity	R-HSA-6807004	1.589898e-01	0.799	0	0
Signaling by NODAL	R-HSA-1181150	1.589898e-01	0.799	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	1.607193e-01	0.794	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	1.622165e-01	0.790	0	0
Regulation of MITF-M dependent genes involved in metabolism	R-HSA-9854907	1.644232e-01	0.784	0	0
Formation of the ternary complex, and subsequently, the 43S complex	R-HSA-72695	1.669619e-01	0.777	0	0
Regulation of PAK-2p34 activity by PS-GAP/RHG10	R-HSA-211728	2.516630e-01	0.599	0	0
TICAM1 deficiency - HSE	R-HSA-5602566	2.516630e-01	0.599	0	0
Impaired BRCA2 binding to SEM1 (DSS1)	R-HSA-9763198	2.516630e-01	0.599	0	0
Hereditary fructose intolerance	R-HSA-5657560	2.516630e-01	0.599	0	0
Defective Mismatch Repair Associated With MSH3	R-HSA-5632927	2.516630e-01	0.599	0	0
Defective Mismatch Repair Associated With MSH6	R-HSA-5632968	2.516630e-01	0.599	0	0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function	R-HSA-9645722	2.516630e-01	0.599	0	0
Impaired BRCA2 translocation to the nucleus	R-HSA-9709275	2.516630e-01	0.599	0	0
MECP2 regulates transcription of genes involved in GABA signaling	R-HSA-9022927	2.164248e-01	0.665	0	0
TLR3-mediated TICAM1-dependent programmed cell death	R-HSA-9013957	2.164248e-01	0.665	0	0
Inhibition of TSC complex formation by PKB	R-HSA-165181	2.164248e-01	0.665	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	2.164248e-01	0.665	0	0
Signaling by MAP2K mutants	R-HSA-9652169	2.164248e-01	0.665	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	2.164248e-01	0.665	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	1.785254e-01	0.748	0	0
Activated NTRK3 signals through PI3K	R-HSA-9603381	1.785254e-01	0.748	0	0
RUNX3 regulates WNT signaling	R-HSA-8951430	1.785254e-01	0.748	0	0
TRIF-mediated programmed cell death	R-HSA-2562578	1.785254e-01	0.748	0	0
SOS-mediated signalling	R-HSA-112412	1.785254e-01	0.748	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	1.785254e-01	0.748	0	0
Type I hemidesmosome assembly	R-HSA-446107	2.151496e-01	0.667	0	0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	R-HSA-9828211	2.151496e-01	0.667	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	2.151496e-01	0.667	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	2.151496e-01	0.667	0	0
Activation of RAC1	R-HSA-428540	1.755096e-01	0.756	0	0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	R-HSA-9824878	1.755096e-01	0.756	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	1.755096e-01	0.756	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	1.679237e-01	0.775	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	2.044721e-01	0.689	0	0
Pervasive developmental disorders	R-HSA-9005895	2.044721e-01	0.689	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	2.044721e-01	0.689	0	0
Disorders of Nervous System Development	R-HSA-9697154	2.044721e-01	0.689	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	2.044721e-01	0.689	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	2.044721e-01	0.689	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	2.044721e-01	0.689	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	2.044721e-01	0.689	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	2.044721e-01	0.689	0	0
Disorders of Developmental Biology	R-HSA-9675151	1.920398e-01	0.717	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	1.920398e-01	0.717	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	2.172834e-01	0.663	0	0
RNA Polymerase III Transcription Initiation From Type 2 Promoter	R-HSA-76066	2.013509e-01	0.696	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	1.868637e-01	0.728	0	0
GAB1 signalosome	R-HSA-180292	2.434791e-01	0.614	0	0
Notch-HLH transcription pathway	R-HSA-350054	2.239284e-01	0.650	0	0
Developmental Lineage of Mammary Stem Cells	R-HSA-9938206	2.239284e-01	0.650	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	2.066617e-01	0.685	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	2.066617e-01	0.685	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	2.066617e-01	0.685	0	0
RUNX2 regulates bone development	R-HSA-8941326	1.774129e-01	0.751	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	1.774129e-01	0.751	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	2.472814e-01	0.607	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	2.272065e-01	0.644	0	0
Negative regulation of FGFR3 signaling	R-HSA-5654732	2.272065e-01	0.644	0	0
HIV elongation arrest and recovery	R-HSA-167287	2.272065e-01	0.644	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	2.272065e-01	0.644	0	0
Signaling by Erythropoietin	R-HSA-9006335	2.484124e-01	0.605	0	0
Negative regulation of FGFR4 signaling	R-HSA-5654733	2.484124e-01	0.605	0	0
DNA Double Strand Break Response	R-HSA-5693606	2.064249e-01	0.685	0	0
Transcriptional regulation by RUNX1	R-HSA-8878171	2.041129e-01	0.690	0	0
RNA Polymerase III Transcription	R-HSA-74158	1.774129e-01	0.751	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	2.013509e-01	0.696	0	0
Chromosome Maintenance	R-HSA-73886	2.461115e-01	0.609	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	1.868637e-01	0.728	0	0
Polo-like kinase mediated events	R-HSA-156711	2.434791e-01	0.614	1	1
Regulation of endogenous retroelements	R-HSA-9842860	2.144263e-01	0.669	0	0
Meiosis	R-HSA-1500620	2.002500e-01	0.698	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	1.921577e-01	0.716	0	0
WNT5A-dependent internalization of FZD4	R-HSA-5099900	1.679237e-01	0.775	0	0
KSRP (KHSRP) binds and destabilizes mRNA	R-HSA-450604	1.679237e-01	0.775	0	0
RNA Polymerase III Transcription Initiation From Type 1 Promoter	R-HSA-76061	2.239284e-01	0.650	0	0
MyD88-independent TLR4 cascade	R-HSA-166166	1.789560e-01	0.747	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	2.239284e-01	0.650	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	1.789560e-01	0.747	0	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	1.908773e-01	0.719	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	1.678935e-01	0.775	0	0
TNF signaling	R-HSA-75893	2.242363e-01	0.649	0	0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	R-HSA-8849469	2.151496e-01	0.667	0	0
Trafficking of AMPA receptors	R-HSA-399719	1.736851e-01	0.760	0	0
Epigenetic regulation of gene expression	R-HSA-212165	2.425339e-01	0.615	0	0
Rab regulation of trafficking	R-HSA-9007101	2.051771e-01	0.688	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	2.396110e-01	0.620	0	0
Repression of WNT target genes	R-HSA-4641265	2.044721e-01	0.689	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	2.021698e-01	0.694	0	0
Signaling by FGFR1	R-HSA-5654736	2.242363e-01	0.649	0	0
Activation and oligomerization of BAK protein	R-HSA-111452	2.516630e-01	0.599	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	2.044721e-01	0.689	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	1.920398e-01	0.717	0	0
DAP12 interactions	R-HSA-2172127	2.275670e-01	0.643	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	2.220791e-01	0.653	0	0
Signaling by FGFR1 in disease	R-HSA-5655302	1.797105e-01	0.745	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	1.809833e-01	0.742	0	0
Ub-specific processing proteases	R-HSA-5689880	2.369492e-01	0.625	0	0
Signaling by TGFB family members	R-HSA-9006936	2.272717e-01	0.643	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	2.184623e-01	0.661	0	0
Signaling by MET	R-HSA-6806834	2.146062e-01	0.668	0	0
CHL1 interactions	R-HSA-447041	1.785254e-01	0.748	0	0
Estrogen-dependent gene expression	R-HSA-9018519	2.336475e-01	0.631	0	0
Protein-protein interactions at synapses	R-HSA-6794362	2.002500e-01	0.698	0	0
Gap junction assembly	R-HSA-190861	2.479748e-01	0.606	0	0
PLC beta mediated events	R-HSA-112043	2.081304e-01	0.682	0	0
Activation of ATR in response to replication stress	R-HSA-176187	2.095409e-01	0.679	0	0
Cell-cell junction organization	R-HSA-421270	1.981670e-01	0.703	0	0
Signaling by Interleukins	R-HSA-449147	2.320403e-01	0.634	0	0
Formation of editosomes by ADAR proteins	R-HSA-77042	2.516630e-01	0.599	0	0
Activation, translocation and oligomerization of BAX	R-HSA-114294	2.516630e-01	0.599	0	0
Inhibition of PKR	R-HSA-169131	2.516630e-01	0.599	0	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	2.164248e-01	0.665	0	0
Signaling by AXIN mutants	R-HSA-4839735	1.755096e-01	0.756	0	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	2.484124e-01	0.605	0	0
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	1.945825e-01	0.711	0	0
Ca-dependent events	R-HSA-111996	1.951228e-01	0.710	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	2.066617e-01	0.685	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	2.472814e-01	0.607	0	0
Host Interactions of HIV factors	R-HSA-162909	2.117754e-01	0.674	0	0
FLT3 signaling in disease	R-HSA-9682385	1.774129e-01	0.751	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	1.831057e-01	0.737	0	0
Signaling by ALK	R-HSA-201556	2.284442e-01	0.641	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	1.785254e-01	0.748	0	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	1.921577e-01	0.716	0	0
Downregulation of ERBB2:ERBB3 signaling	R-HSA-1358803	2.044721e-01	0.689	0	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	2.284677e-01	0.641	0	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	2.045090e-01	0.689	0	0
Cytochrome c-mediated apoptotic response	R-HSA-111461	1.755096e-01	0.756	0	0
Syndecan interactions	R-HSA-3000170	2.472814e-01	0.607	0	0
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	2.095409e-01	0.679	0	0
Apoptotic factor-mediated response	R-HSA-111471	2.434791e-01	0.614	0	0
Glycolysis	R-HSA-70171	1.932761e-01	0.714	0	0
SLC-mediated transport of inorganic anions	R-HSA-9958790	2.108466e-01	0.676	0	0
Cation-coupled Chloride cotransporters	R-HSA-426117	1.785254e-01	0.748	0	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	2.013509e-01	0.696	1	1
ARMS-mediated activation	R-HSA-170984	2.531604e-01	0.597	0	0
MAPK1 (ERK2) activation	R-HSA-112411	2.531604e-01	0.597	0	0
Unwinding of DNA	R-HSA-176974	2.531604e-01	0.597	0	0
HuR (ELAVL1) binds and stabilizes mRNA	R-HSA-450520	2.531604e-01	0.597	0	0
Regulation of CDH11 gene transcription	R-HSA-9762293	2.531604e-01	0.597	0	0
NOTCH4 Activation and Transmission of Signal to the Nucleus	R-HSA-9013700	2.531604e-01	0.597	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	2.569041e-01	0.590	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	2.584144e-01	0.588	0	0
Neurexins and neuroligins	R-HSA-6794361	2.584144e-01	0.588	0	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	2.616330e-01	0.582	0	0
Defective Mismatch Repair Associated With MSH2	R-HSA-5632928	3.526488e-01	0.453	0	0
IKBKB deficiency causes SCID	R-HSA-5602636	3.526488e-01	0.453	0	0
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)	R-HSA-5619039	3.526488e-01	0.453	0	0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	R-HSA-5603027	3.526488e-01	0.453	0	0
TRAF3 deficiency - HSE	R-HSA-5602571	3.526488e-01	0.453	0	0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	R-HSA-5619054	3.526488e-01	0.453	0	0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)	R-HSA-5619050	3.526488e-01	0.453	0	0
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)	R-HSA-5619045	3.526488e-01	0.453	0	0
Signaling by TCF7L2 mutants	R-HSA-5339700	3.526488e-01	0.453	0	0
Defective SLC34A2 causes PALM	R-HSA-5687583	3.526488e-01	0.453	0	0
Defective SLC17A5 causes Salla disease (SD) and ISSD	R-HSA-5619035	3.526488e-01	0.453	0	0
Defective GFPT1 causes CMSTA1	R-HSA-4085023	3.526488e-01	0.453	0	0
RUNX2 regulates chondrocyte maturation	R-HSA-8941284	2.696108e-01	0.569	0	0
Loss of phosphorylation of MECP2 at T308	R-HSA-9022535	2.696108e-01	0.569	0	0
SLIT2:ROBO1 increases RHOA activity	R-HSA-8985586	3.227153e-01	0.491	0	0
CDC6 association with the ORC:origin complex	R-HSA-68689	3.227153e-01	0.491	0	0
IkBA variant leads to EDA-ID	R-HSA-5603029	3.227153e-01	0.491	0	0
Stimulation of the cell death response by PAK-2p34	R-HSA-211736	4.400119e-01	0.357	0	0
Activation, myristolyation of BID and translocation to mitochondria	R-HSA-75108	4.400119e-01	0.357	0	0
Signalling to ERK5	R-HSA-198765	4.400119e-01	0.357	0	0
Signaling by RAS GAP mutants	R-HSA-9753510	4.400119e-01	0.357	0	0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)	R-HSA-5655799	4.400119e-01	0.357	0	0
TGFBR2 Kinase Domain Mutants in Cancer	R-HSA-3645790	4.400119e-01	0.357	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	2.920155e-01	0.535	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	2.920155e-01	0.535	0	0
Erythropoietin activates Phospholipase C gamma (PLCG)	R-HSA-9027277	2.920155e-01	0.535	0	0
CRMPs in Sema3A signaling	R-HSA-399956	2.659003e-01	0.575	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	3.747925e-01	0.426	0	0
Erythropoietin activates STAT5	R-HSA-9027283	3.747925e-01	0.426	0	0
RAS signaling downstream of NF1 loss-of-function variants	R-HSA-6802953	3.747925e-01	0.426	0	0
E2F-enabled inhibition of pre-replication complex formation	R-HSA-113507	3.747925e-01	0.426	0	0
InlA-mediated entry of Listeria monocytogenes into host cells	R-HSA-8876493	3.312265e-01	0.480	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	3.312265e-01	0.480	0	0
Erythropoietin activates RAS	R-HSA-9027284	2.977914e-01	0.526	0	0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	R-HSA-2173791	2.977914e-01	0.526	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	2.977914e-01	0.526	0	0
RIP-mediated NFkB activation via ZBP1	R-HSA-1810476	2.977914e-01	0.526	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	2.977914e-01	0.526	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	2.980142e-01	0.526	0	0
Regulation of NF-kappa B signaling	R-HSA-9758274	3.301028e-01	0.481	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	3.301028e-01	0.481	0	0
Phosphorylation of the APC/C	R-HSA-176412	3.301028e-01	0.481	1	1
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	3.301028e-01	0.481	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	3.703631e-01	0.431	0	0
PI3K events in ERBB4 signaling	R-HSA-1250342	3.703631e-01	0.431	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	3.703631e-01	0.431	0	0
MECP2 regulates transcription factors	R-HSA-9022707	4.251528e-01	0.371	0	0
MET activates PI3K/AKT signaling	R-HSA-8851907	4.251528e-01	0.371	0	0
Netrin mediated repulsion signals	R-HSA-418886	4.251528e-01	0.371	0	0
PLC-gamma1 signalling	R-HSA-167021	5.155893e-01	0.288	0	0
Activated NTRK3 signals through PLCG1	R-HSA-9034793	5.155893e-01	0.288	0	0
Axonal growth stimulation	R-HSA-209563	5.155893e-01	0.288	0	0
TFAP2 (AP-2) family regulates transcription of other transcription factors	R-HSA-8866906	5.155893e-01	0.288	0	0
Defective ABCA1 causes TGD	R-HSA-5682113	5.155893e-01	0.288	0	0
Loss of Function of KMT2D in Kabuki Syndrome	R-HSA-9944971	5.155893e-01	0.288	0	0
Adrenaline signalling through Alpha-2 adrenergic receptor	R-HSA-392023	5.155893e-01	0.288	0	0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome	R-HSA-9944997	5.155893e-01	0.288	0	0
Defective ABCC2 causes DJS	R-HSA-5679001	5.155893e-01	0.288	0	0
MET activates PTPN11	R-HSA-8865999	5.155893e-01	0.288	0	0
Activation of the pre-replicative complex	R-HSA-68962	2.701903e-01	0.568	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	3.260012e-01	0.487	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	3.260012e-01	0.487	0	0
SHC1 events in ERBB4 signaling	R-HSA-1250347	3.625821e-01	0.441	0	0
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	4.090540e-01	0.388	0	0
RUNX3 regulates p14-ARF	R-HSA-8951936	4.090540e-01	0.388	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	4.090540e-01	0.388	0	0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	R-HSA-9820865	4.090540e-01	0.388	0	0
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	3.542417e-01	0.451	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	3.459996e-01	0.461	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	3.949976e-01	0.403	0	0
Activated NTRK2 signals through FYN	R-HSA-9032500	4.733114e-01	0.325	0	0
Nef mediated downregulation of MHC class I complex cell surface expression	R-HSA-164940	4.733114e-01	0.325	0	0
phospho-PLA2 pathway	R-HSA-111995	4.733114e-01	0.325	0	0
Formyl peptide receptors bind formyl peptides and many other ligands	R-HSA-444473	4.733114e-01	0.325	0	0
EGFR interacts with phospholipase C-gamma	R-HSA-212718	4.733114e-01	0.325	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	4.733114e-01	0.325	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	2.751299e-01	0.560	0	0
RNA Polymerase III Transcription Initiation From Type 3 Promoter	R-HSA-76071	3.825757e-01	0.417	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	4.469863e-01	0.350	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	4.469863e-01	0.350	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	4.271394e-01	0.369	0	0
Signaling by ERBB4	R-HSA-1236394	3.061112e-01	0.514	0	0
Negative regulation of FGFR2 signaling	R-HSA-5654727	3.844696e-01	0.415	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	3.082979e-01	0.511	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	3.627464e-01	0.440	0	0
ADP signalling through P2Y purinoceptor 1	R-HSA-418592	4.389355e-01	0.358	0	0
Deadenylation of mRNA	R-HSA-429947	4.389355e-01	0.358	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	4.588212e-01	0.338	0	0
IKK complex recruitment mediated by RIP1	R-HSA-937041	4.588212e-01	0.338	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	4.588212e-01	0.338	0	0
MASTL Facilitates Mitotic Progression	R-HSA-2465910	5.189455e-01	0.285	0	0
Inactivation of CDC42 and RAC1	R-HSA-428543	5.189455e-01	0.285	0	0
WNT mediated activation of DVL	R-HSA-201688	5.189455e-01	0.285	0	0
Calcineurin activates NFAT	R-HSA-2025928	5.189455e-01	0.285	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	2.959475e-01	0.529	0	0
Meiotic synapsis	R-HSA-1221632	3.916730e-01	0.407	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	3.916730e-01	0.407	0	0
Cap-dependent Translation Initiation	R-HSA-72737	3.388429e-01	0.470	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	4.898798e-01	0.310	0	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	3.809299e-01	0.419	0	0
Signaling by PDGFRA extracellular domain mutants	R-HSA-9673770	5.195922e-01	0.284	0	0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants	R-HSA-9673767	5.195922e-01	0.284	0	0
TICAM1, RIP1-mediated IKK complex recruitment	R-HSA-168927	5.195922e-01	0.284	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	4.940190e-01	0.306	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	4.042479e-01	0.393	0	0
RNA Polymerase I Transcription Termination	R-HSA-73863	5.208043e-01	0.283	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	5.221404e-01	0.282	0	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	5.221404e-01	0.282	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	5.221404e-01	0.282	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	5.221404e-01	0.282	0	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	5.071935e-01	0.295	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	5.228198e-01	0.282	0	0
Transcription of the HIV genome	R-HSA-167172	3.127546e-01	0.505	0	0
Eukaryotic Translation Initiation	R-HSA-72613	3.388429e-01	0.470	0	0
DNA Damage Bypass	R-HSA-73893	3.161626e-01	0.500	0	0
Mismatch Repair	R-HSA-5358508	4.271394e-01	0.369	0	0
Negative regulation of FGFR1 signaling	R-HSA-5654726	3.380433e-01	0.471	0	0
DNA strand elongation	R-HSA-69190	4.725194e-01	0.326	0	0
HIV Transcription Elongation	R-HSA-167169	5.221404e-01	0.282	0	0
Formation of definitive endoderm	R-HSA-9823730	2.980142e-01	0.526	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	3.825757e-01	0.417	0	0
MET promotes cell motility	R-HSA-8875878	4.771138e-01	0.321	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	3.949976e-01	0.403	0	0
Sensing of DNA Double Strand Breaks	R-HSA-5693548	3.703631e-01	0.431	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	3.260012e-01	0.487	0	0
FOXO-mediated transcription	R-HSA-9614085	3.350625e-01	0.475	0	0
Integrin signaling	R-HSA-354192	3.380433e-01	0.471	0	0
HSF1-dependent transactivation	R-HSA-3371571	4.841145e-01	0.315	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	5.221404e-01	0.282	0	0
TICAM1-dependent activation of IRF3/IRF7	R-HSA-9013973	3.703631e-01	0.431	0	0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	R-HSA-936964	3.625821e-01	0.441	0	0
G-protein beta:gamma signalling	R-HSA-397795	4.971965e-01	0.303	0	0
Fanconi Anemia Pathway	R-HSA-6783310	5.019937e-01	0.299	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	4.222588e-01	0.374	0	0
TP53 Regulates Transcription of Death Receptors and Ligands	R-HSA-6803211	4.839015e-01	0.315	0	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	4.490152e-01	0.348	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	2.920155e-01	0.535	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	4.352514e-01	0.361	0	0
Negative regulation of MAPK pathway	R-HSA-5675221	2.841402e-01	0.546	0	0
UCH proteinases	R-HSA-5689603	4.441068e-01	0.353	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	5.019937e-01	0.299	0	0
Signaling by PDGF	R-HSA-186797	3.197224e-01	0.495	0	0
PI3K/AKT activation	R-HSA-198203	2.920155e-01	0.535	0	0
G alpha (12/13) signalling events	R-HSA-416482	2.711756e-01	0.567	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	4.997900e-01	0.301	0	0
RNA Polymerase I Transcription	R-HSA-73864	4.772014e-01	0.321	0	0
Signaling by FGFR2	R-HSA-5654738	2.997594e-01	0.523	0	0
Interferon gamma signaling	R-HSA-877300	4.210394e-01	0.376	0	0
Insulin receptor signalling cascade	R-HSA-74751	3.535653e-01	0.452	0	0
MAPK3 (ERK1) activation	R-HSA-110056	2.920155e-01	0.535	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	3.625821e-01	0.441	0	0
Regulation of IFNG signaling	R-HSA-877312	4.090540e-01	0.388	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	3.732969e-01	0.428	0	0
AMPK inhibits chREBP transcriptional activation activity	R-HSA-163680	5.189455e-01	0.285	0	0
Activation of the TFAP2 (AP-2) family of transcription factors	R-HSA-8866907	5.189455e-01	0.285	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	4.940190e-01	0.306	0	0
Interleukin-6 family signaling	R-HSA-6783589	4.389355e-01	0.358	0	0
Germ layer formation at gastrulation	R-HSA-9754189	2.704487e-01	0.568	0	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	4.509218e-01	0.346	0	0
Signaling by ROBO receptors	R-HSA-376176	3.966805e-01	0.402	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	2.651456e-01	0.577	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	3.197224e-01	0.495	1	1
Signaling by WNT in cancer	R-HSA-4791275	4.725194e-01	0.326	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	4.647464e-01	0.333	0	0
Signaling by FGFR	R-HSA-190236	5.134338e-01	0.290	0	0
Hydroxycarboxylic acid-binding receptors	R-HSA-3296197	2.696108e-01	0.569	0	0
Diseases of Mismatch Repair (MMR)	R-HSA-5423599	5.155893e-01	0.288	0	0
Metalloprotease DUBs	R-HSA-5689901	3.207691e-01	0.494	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	3.949976e-01	0.403	0	0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	R-HSA-8866904	4.733114e-01	0.325	0	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	4.839015e-01	0.315	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	4.839015e-01	0.315	0	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	4.647464e-01	0.333	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	5.042711e-01	0.297	0	0
rRNA processing in the nucleus and cytosol	R-HSA-8868773	5.249712e-01	0.280	0	0
G-protein mediated events	R-HSA-112040	2.969495e-01	0.527	0	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	5.042711e-01	0.297	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	3.296814e-01	0.482	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	2.977914e-01	0.526	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	3.147817e-01	0.502	0	0
Opioid Signalling	R-HSA-111885	5.002803e-01	0.301	0	0
p75NTR regulates axonogenesis	R-HSA-193697	5.189455e-01	0.285	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	3.809299e-01	0.419	0	0
Reproduction	R-HSA-1474165	3.726422e-01	0.429	0	0
Aryl hydrocarbon receptor signalling	R-HSA-8937144	3.227153e-01	0.491	0	0
ATF6 (ATF6-alpha) activates chaperone genes	R-HSA-381183	3.703631e-01	0.431	0	0
Signalling to RAS	R-HSA-167044	3.260012e-01	0.487	0	0
Transcriptional regulation by small RNAs	R-HSA-5578749	2.762072e-01	0.559	0	0
Intra-Golgi traffic	R-HSA-6811438	4.165269e-01	0.380	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	4.725194e-01	0.326	0	0
HATs acetylate histones	R-HSA-3214847	4.284236e-01	0.368	0	0
ESR-mediated signaling	R-HSA-8939211	2.892021e-01	0.539	0	0
Interleukin-7 signaling	R-HSA-1266695	2.958249e-01	0.529	0	0
Neurofascin interactions	R-HSA-447043	3.747925e-01	0.426	0	0
Rap1 signalling	R-HSA-392517	2.704487e-01	0.568	0	0
ROBO receptors bind AKAP5	R-HSA-9010642	4.733114e-01	0.325	0	0
Developmental Biology	R-HSA-1266738	2.775745e-01	0.557	1	0
MAP kinase activation	R-HSA-450294	3.030925e-01	0.518	0	0
PI Metabolism	R-HSA-1483255	2.892687e-01	0.539	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	3.611967e-01	0.442	0	0
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	5.236069e-01	0.281	0	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	4.940190e-01	0.306	0	0
Gene Silencing by RNA	R-HSA-211000	4.599382e-01	0.337	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	4.971965e-01	0.303	0	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	4.140025e-01	0.383	0	0
Interleukin-17 signaling	R-HSA-448424	4.572370e-01	0.340	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	2.904148e-01	0.537	0	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	4.140025e-01	0.383	0	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	4.140025e-01	0.383	0	0
Manipulation of host energy metabolism	R-HSA-9636667	3.526488e-01	0.453	0	0
Transport of connexins along the secretory pathway	R-HSA-190827	3.526488e-01	0.453	0	0
Reelin signalling pathway	R-HSA-8866376	2.696108e-01	0.569	0	0
Sodium-coupled phosphate cotransporters	R-HSA-427652	3.227153e-01	0.491	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	3.227153e-01	0.491	0	0
mRNA Editing: A to I Conversion	R-HSA-75064	4.400119e-01	0.357	0	0
tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis	R-HSA-9708296	4.400119e-01	0.357	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	4.400119e-01	0.357	0	0
Loss of Function of TGFBR2 in Cancer	R-HSA-3642278	4.400119e-01	0.357	0	0
Neurophilin interactions with VEGF and VEGFR	R-HSA-194306	4.400119e-01	0.357	0	0
C6 deamination of adenosine	R-HSA-75102	4.400119e-01	0.357	0	0
Bicarbonate transporters	R-HSA-425381	3.312265e-01	0.480	0	0
Regulation of PTEN localization	R-HSA-8948747	4.251528e-01	0.371	0	0
MET interacts with TNS proteins	R-HSA-8875513	5.155893e-01	0.288	0	0
Type II Na+/Pi cotransporters	R-HSA-427589	5.155893e-01	0.288	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	3.207691e-01	0.494	0	0
Signaling by LTK	R-HSA-9842663	4.090540e-01	0.388	0	0
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	4.090540e-01	0.388	0	0
Axonal growth inhibition (RHOA activation)	R-HSA-193634	4.733114e-01	0.325	0	0
Synaptic adhesion-like molecules	R-HSA-8849932	4.271394e-01	0.369	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	4.271394e-01	0.369	0	0
Estrogen-stimulated signaling through PRKCZ	R-HSA-9634635	5.189455e-01	0.285	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	3.944342e-01	0.404	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	5.087643e-01	0.293	0	0
GPVI-mediated activation cascade	R-HSA-114604	4.310373e-01	0.365	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	5.208043e-01	0.283	0	0
Signaling by NTRK3 (TRKC)	R-HSA-9034015	3.542417e-01	0.451	0	0
p75NTR signals via NF-kB	R-HSA-193639	5.195922e-01	0.284	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	3.380433e-01	0.471	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	3.985309e-01	0.400	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	4.488165e-01	0.348	0	0
CD163 mediating an anti-inflammatory response	R-HSA-9662834	3.312265e-01	0.480	0	0
p75NTR recruits signalling complexes	R-HSA-209543	4.090540e-01	0.388	0	0
The NLRP3 inflammasome	R-HSA-844456	4.588212e-01	0.338	0	0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	R-HSA-8866652	3.459996e-01	0.461	0	0
Calmodulin induced events	R-HSA-111933	2.884560e-01	0.540	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	4.533814e-01	0.344	0	0
Signaling by PTK6	R-HSA-8848021	4.533814e-01	0.344	0	0
NRIF signals cell death from the nucleus	R-HSA-205043	4.839015e-01	0.315	0	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	4.975095e-01	0.303	0	0
CaM pathway	R-HSA-111997	2.884560e-01	0.540	0	0
Signaling by Activin	R-HSA-1502540	2.977914e-01	0.526	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	3.949014e-01	0.404	0	0
TGFBR3 expression	R-HSA-9839394	2.958249e-01	0.529	0	0
Platelet Adhesion to exposed collagen	R-HSA-75892	4.469863e-01	0.350	0	0
rRNA modification in the nucleus and cytosol	R-HSA-6790901	3.365584e-01	0.473	0	0
ZBP1(DAI) mediated induction of type I IFNs	R-HSA-1606322	4.271394e-01	0.369	0	0
Breakdown of the nuclear lamina	R-HSA-352238	3.526488e-01	0.453	0	0
Oligomerization of connexins into connexons	R-HSA-190704	3.526488e-01	0.453	0	0
DSCAM interactions	R-HSA-376172	4.400119e-01	0.357	0	0
Regulation of the apoptosome activity	R-HSA-9627069	2.920155e-01	0.535	0	0
TGFBR3 PTM regulation	R-HSA-9839383	4.733114e-01	0.325	0	0
Maturation of nucleoprotein	R-HSA-9683610	4.469863e-01	0.350	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	4.469863e-01	0.350	1	1
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	5.201753e-01	0.284	0	0
Formation of apoptosome	R-HSA-111458	2.920155e-01	0.535	0	0
ATF6 (ATF6-alpha) activates chaperones	R-HSA-381033	4.469863e-01	0.350	0	0
Maturation of nucleoprotein	R-HSA-9694631	2.704487e-01	0.568	0	0
NRAGE signals death through JNK	R-HSA-193648	3.270540e-01	0.485	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	3.127546e-01	0.505	0	0
PTEN Regulation	R-HSA-6807070	2.636000e-01	0.579	0	0
Formation of the anterior neural plate	R-HSA-9823739	5.195922e-01	0.284	0	0
Regulation of MITF-M-dependent genes involved in apoptosis	R-HSA-9824594	5.201753e-01	0.284	0	0
Early Phase of HIV Life Cycle	R-HSA-162594	5.201753e-01	0.284	0	0
Inositol phosphate metabolism	R-HSA-1483249	4.351989e-01	0.361	0	0
Nectin/Necl trans heterodimerization	R-HSA-420597	2.696108e-01	0.569	0	0
RSK activation	R-HSA-444257	4.733114e-01	0.325	0	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	5.189455e-01	0.285	0	0
Glucose metabolism	R-HSA-70326	4.382387e-01	0.358	0	0
CaMK IV-mediated phosphorylation of CREB	R-HSA-111932	2.920155e-01	0.535	0	0
Sensory processing of sound	R-HSA-9659379	4.936294e-01	0.307	0	0
Signaling by TGFBR3	R-HSA-9839373	3.832599e-01	0.417	0	0
Uptake and function of diphtheria toxin	R-HSA-5336415	4.251528e-01	0.371	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	3.844696e-01	0.415	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	5.189455e-01	0.285	0	0
Respiratory syncytial virus genome replication	R-HSA-9834752	5.189455e-01	0.285	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	5.195922e-01	0.284	0	0
Regulation of beta-cell development	R-HSA-186712	5.056371e-01	0.296	0	0
SARS-CoV-1-host interactions	R-HSA-9692914	4.459438e-01	0.351	0	0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	R-HSA-9926550	4.271394e-01	0.369	0	0
Sealing of the nuclear envelope (NE) by ESCRT-III	R-HSA-9668328	3.380433e-01	0.471	0	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	3.270540e-01	0.485	0	0
Growth hormone receptor signaling	R-HSA-982772	4.108533e-01	0.386	0	0
STING mediated induction of host immune responses	R-HSA-1834941	4.588212e-01	0.338	0	0
Signaling by FGFR in disease	R-HSA-1226099	5.254778e-01	0.279	0	0
HCMV Early Events	R-HSA-9609690	5.360253e-01	0.271	0	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	5.421538e-01	0.266	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	5.424635e-01	0.266	0	0
SARS-CoV-2 modulates host translation machinery	R-HSA-9754678	5.428053e-01	0.265	0	0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	R-HSA-6814122	5.452550e-01	0.263	0	0
Dual Incision in GG-NER	R-HSA-5696400	5.452550e-01	0.263	0	0
Mitophagy	R-HSA-5205647	5.452550e-01	0.263	0	0
Phase 0 - rapid depolarisation	R-HSA-5576892	5.469626e-01	0.262	0	0
PINK1-PRKN Mediated Mitophagy	R-HSA-5205685	5.469626e-01	0.262	0	0
Inactivation of CSF3 (G-CSF) signaling	R-HSA-9705462	5.495901e-01	0.260	0	0
Mitochondrial calcium ion transport	R-HSA-8949215	5.495901e-01	0.260	0	0
Class I peroxisomal membrane protein import	R-HSA-9603798	5.538973e-01	0.257	0	0
Killing mechanisms	R-HSA-9664420	5.538973e-01	0.257	0	0
WNT5:FZD7-mediated leishmania damping	R-HSA-9673324	5.538973e-01	0.257	0	0
TP53 Regulates Transcription of Caspase Activators and Caspases	R-HSA-6803207	5.538973e-01	0.257	0	0
Caspase activation via Death Receptors in the presence of ligand	R-HSA-140534	5.538973e-01	0.257	0	0
Negative regulation of FLT3	R-HSA-9706369	5.538973e-01	0.257	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	5.538973e-01	0.257	0	0
Cardiac conduction	R-HSA-5576891	5.558995e-01	0.255	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	5.566623e-01	0.254	0	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	5.586241e-01	0.253	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	5.604976e-01	0.251	0	0
HDACs deacetylate histones	R-HSA-3214815	5.618097e-01	0.250	0	0
2-LTR circle formation	R-HSA-164843	5.618593e-01	0.250	0	0
Activation of Ca-permeable Kainate Receptor	R-HSA-451308	5.618593e-01	0.250	0	0
Pexophagy	R-HSA-9664873	5.618593e-01	0.250	0	0
Interleukin-27 signaling	R-HSA-9020956	5.618593e-01	0.250	0	0
Josephin domain DUBs	R-HSA-5689877	5.618593e-01	0.250	0	0
Assembly and release of respiratory syncytial virus (RSV) virions	R-HSA-9820962	5.618593e-01	0.250	0	0
Signaling by Leptin	R-HSA-2586552	5.618593e-01	0.250	0	0
Intraflagellar transport	R-HSA-5620924	5.634808e-01	0.249	0	0
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	5.656431e-01	0.247	0	0
HIV Transcription Initiation	R-HSA-167161	5.656431e-01	0.247	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	5.656431e-01	0.247	0	0
Cellular response to chemical stress	R-HSA-9711123	5.674276e-01	0.246	0	0
PERK regulates gene expression	R-HSA-381042	5.685049e-01	0.245	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	5.685049e-01	0.245	0	0
Oncogene Induced Senescence	R-HSA-2559585	5.685049e-01	0.245	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	5.701067e-01	0.244	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	5.724172e-01	0.242	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	5.724172e-01	0.242	0	0
Endosomal Sorting Complex Required For Transport (ESCRT)	R-HSA-917729	5.724172e-01	0.242	0	0
Signaling by CSF3 (G-CSF)	R-HSA-9674555	5.724172e-01	0.242	0	0
Platelet calcium homeostasis	R-HSA-418360	5.724172e-01	0.242	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	5.763977e-01	0.239	0	0
FGFR2 alternative splicing	R-HSA-6803529	5.780275e-01	0.238	0	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	5.780275e-01	0.238	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	5.780275e-01	0.238	0	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	5.780275e-01	0.238	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	5.804759e-01	0.236	0	0
Alternative complement activation	R-HSA-173736	5.809704e-01	0.236	0	0
Activated NTRK2 signals through PLCG1	R-HSA-9026527	5.809704e-01	0.236	0	0
p75NTR negatively regulates cell cycle via SC1	R-HSA-193670	5.809704e-01	0.236	0	0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine	R-HSA-9735763	5.809704e-01	0.236	0	0
Nucleotide catabolism defects	R-HSA-9735786	5.809704e-01	0.236	0	0
Defective LFNG causes SCDO3	R-HSA-5083630	5.809704e-01	0.236	0	0
TFAP2 (AP-2) family regulates transcription of cell cycle factors	R-HSA-8866911	5.809704e-01	0.236	0	0
TNFR1-mediated ceramide production	R-HSA-5626978	5.809704e-01	0.236	0	0
SARS-CoV-1-mediated effects on programmed cell death	R-HSA-9692913	5.809704e-01	0.236	0	0
Transcriptional activation of cell cycle inhibitor p21	R-HSA-69895	5.809704e-01	0.236	0	0
Transcriptional activation of p53 responsive genes	R-HSA-69560	5.809704e-01	0.236	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	5.809704e-01	0.236	0	0
NADE modulates death signalling	R-HSA-205025	5.809704e-01	0.236	0	0
Regulation of HMOX1 expression and activity	R-HSA-9707587	5.809704e-01	0.236	0	0
Platelet degranulation	R-HSA-114608	5.811458e-01	0.236	0	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	5.818802e-01	0.235	0	0
Developmental Cell Lineages	R-HSA-9734767	5.851617e-01	0.233	0	0
mRNA decay by 5' to 3' exoribonuclease	R-HSA-430039	5.866971e-01	0.232	0	0
tRNA modification in the mitochondrion	R-HSA-6787450	5.866971e-01	0.232	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	5.873556e-01	0.231	0	0
PCP/CE pathway	R-HSA-4086400	5.908564e-01	0.229	0	0
HSF1 activation	R-HSA-3371511	5.911607e-01	0.228	0	0
G1/S-Specific Transcription	R-HSA-69205	5.911607e-01	0.228	0	0
IGF1R signaling cascade	R-HSA-2428924	5.956601e-01	0.225	0	0
TCR signaling	R-HSA-202403	5.970296e-01	0.224	0	0
Thrombin signalling through proteinase activated receptors (PARs)	R-HSA-456926	5.971038e-01	0.224	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	5.971038e-01	0.224	0	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	5.971038e-01	0.224	0	0
IRS-mediated signalling	R-HSA-112399	5.987734e-01	0.223	0	0
Adaptive Immune System	R-HSA-1280218	5.991436e-01	0.222	0	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	5.997246e-01	0.222	0	0
RHOBTB3 ATPase cycle	R-HSA-9706019	6.019560e-01	0.220	0	0
Formation of the posterior neural plate	R-HSA-9832991	6.019560e-01	0.220	0	0
Synthesis of PI	R-HSA-1483226	6.019560e-01	0.220	0	0
Interleukin-2 signaling	R-HSA-9020558	6.019560e-01	0.220	0	0
Ionotropic activity of kainate receptors	R-HSA-451306	6.019560e-01	0.220	0	0
ChREBP activates metabolic gene expression	R-HSA-163765	6.019560e-01	0.220	0	0
PI3K Cascade	R-HSA-109704	6.025548e-01	0.220	0	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	6.054110e-01	0.218	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	6.054110e-01	0.218	0	0
G beta:gamma signalling through PI3Kgamma	R-HSA-392451	6.054110e-01	0.218	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	6.072360e-01	0.217	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	6.126809e-01	0.213	0	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	6.127371e-01	0.213	0	0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	6.131764e-01	0.212	0	0
Ovarian tumor domain proteases	R-HSA-5689896	6.131764e-01	0.212	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	6.179080e-01	0.209	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	6.179080e-01	0.209	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	6.209695e-01	0.207	0	0
Mitochondrial biogenesis	R-HSA-1592230	6.212522e-01	0.207	0	0
Meiotic recombination	R-HSA-912446	6.214123e-01	0.207	0	0
SARS-CoV Infections	R-HSA-9679506	6.245384e-01	0.204	0	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	6.264635e-01	0.203	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	6.274011e-01	0.202	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	6.280466e-01	0.202	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	6.316820e-01	0.200	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	6.371348e-01	0.196	0	0
RUNX1 regulates transcription of genes involved in interleukin signaling	R-HSA-8939247	6.375302e-01	0.195	0	0
NTRK2 activates RAC1	R-HSA-9032759	6.375302e-01	0.195	0	0
FLT3 signaling by CBL mutants	R-HSA-9706377	6.375302e-01	0.195	0	0
Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA)	R-HSA-5619067	6.375302e-01	0.195	0	0
Activation of C3 and C5	R-HSA-174577	6.375302e-01	0.195	0	0
Resolution of AP sites via the single-nucleotide replacement pathway	R-HSA-110381	6.375302e-01	0.195	0	0
Activation of AKT2	R-HSA-165158	6.375302e-01	0.195	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	6.375302e-01	0.195	0	0
Muscarinic acetylcholine receptors	R-HSA-390648	6.375302e-01	0.195	0	0
Pyrophosphate hydrolysis	R-HSA-71737	6.375302e-01	0.195	0	0
Inositol transporters	R-HSA-429593	6.375302e-01	0.195	0	0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	R-HSA-111464	6.375302e-01	0.195	0	0
SMAC (DIABLO) binds to IAPs	R-HSA-111463	6.375302e-01	0.195	0	0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	R-HSA-3134963	6.375302e-01	0.195	0	0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	R-HSA-9623433	6.392141e-01	0.194	0	0
Sema4D mediated inhibition of cell attachment and migration	R-HSA-416550	6.392141e-01	0.194	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	6.392141e-01	0.194	0	0
Endosomal/Vacuolar pathway	R-HSA-1236977	6.392141e-01	0.194	0	0
Reduction of cytosolic Ca++ levels	R-HSA-418359	6.392141e-01	0.194	0	0
NF-kB is activated and signals survival	R-HSA-209560	6.392141e-01	0.194	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	6.392141e-01	0.194	0	0
Integration of provirus	R-HSA-162592	6.392141e-01	0.194	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	6.397799e-01	0.194	0	0
Signaling by NOTCH4	R-HSA-9013694	6.411396e-01	0.193	0	0
G1/S Transition	R-HSA-69206	6.436582e-01	0.191	0	0
G0 and Early G1	R-HSA-1538133	6.439721e-01	0.191	0	0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells	R-HSA-9937080	6.439721e-01	0.191	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	6.466213e-01	0.189	0	0
RNA Polymerase III Transcription Termination	R-HSA-73980	6.474784e-01	0.189	0	0
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	6.474784e-01	0.189	0	0
Platelet sensitization by LDL	R-HSA-432142	6.474784e-01	0.189	0	0
Tie2 Signaling	R-HSA-210993	6.474784e-01	0.189	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9679504	6.474784e-01	0.189	0	0
Diseases of programmed cell death	R-HSA-9645723	6.479670e-01	0.188	0	0
Influenza Infection	R-HSA-168255	6.507069e-01	0.187	0	0
SARS-CoV-2 Infection	R-HSA-9694516	6.533167e-01	0.185	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	6.564741e-01	0.183	0	0
Protein ubiquitination	R-HSA-8852135	6.564741e-01	0.183	0	0
Acyl chain remodelling of PS	R-HSA-1482801	6.567988e-01	0.183	0	0
Formation of the nephric duct	R-HSA-9830364	6.567988e-01	0.183	0	0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	6.616947e-01	0.179	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	6.653826e-01	0.177	0	0
Nuclear RNA decay	R-HSA-9930044	6.660796e-01	0.176	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	6.660796e-01	0.176	0	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	6.729600e-01	0.172	0	0
Leishmania phagocytosis	R-HSA-9664417	6.729600e-01	0.172	0	0
Parasite infection	R-HSA-9664407	6.729600e-01	0.172	0	0
Leading Strand Synthesis	R-HSA-69109	6.736694e-01	0.172	0	0
Polymerase switching	R-HSA-69091	6.736694e-01	0.172	0	0
Scavenging by Class F Receptors	R-HSA-3000484	6.736694e-01	0.172	0	0
Interleukin-15 signaling	R-HSA-8983432	6.736694e-01	0.172	0	0
SHC-related events triggered by IGF1R	R-HSA-2428933	6.736694e-01	0.172	0	0
Role of second messengers in netrin-1 signaling	R-HSA-418890	6.736694e-01	0.172	0	0
VLDLR internalisation and degradation	R-HSA-8866427	6.736694e-01	0.172	0	0
Activated NTRK2 signals through FRS2 and FRS3	R-HSA-9028731	6.736694e-01	0.172	0	0
GRB2 events in EGFR signaling	R-HSA-179812	6.736694e-01	0.172	0	0
Interleukin-35 Signalling	R-HSA-8984722	6.736694e-01	0.172	0	0
Reversal of alkylation damage by DNA dioxygenases	R-HSA-73943	6.736694e-01	0.172	0	0
MET activates RAS signaling	R-HSA-8851805	6.736694e-01	0.172	0	0
Diseases of Immune System	R-HSA-5260271	6.750324e-01	0.171	0	0
Diseases associated with the TLR signaling cascade	R-HSA-5602358	6.750324e-01	0.171	0	0
Translesion Synthesis by POLH	R-HSA-110320	6.753836e-01	0.170	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	6.753836e-01	0.170	0	0
Specification of the neural plate border	R-HSA-9834899	6.753836e-01	0.170	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	6.753836e-01	0.170	0	0
Other interleukin signaling	R-HSA-449836	6.753836e-01	0.170	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	6.807343e-01	0.167	0	0
Caspase activation via extrinsic apoptotic signalling pathway	R-HSA-5357769	6.807343e-01	0.167	0	0
Carboxyterminal post-translational modifications of tubulin	R-HSA-8955332	6.835850e-01	0.165	0	0
Inhibition of Signaling by Overexpressed EGFR	R-HSA-5638303	6.864585e-01	0.163	0	0
Signaling by Overexpressed Wild-Type EGFR in Cancer	R-HSA-5638302	6.864585e-01	0.163	0	0
Signaling by MAPK mutants	R-HSA-9652817	6.864585e-01	0.163	0	0
Loss-of-function mutations in DBT cause MSUD2	R-HSA-9865113	6.864585e-01	0.163	0	0
Loss-of-function mutations in DLD cause MSUD3/DLDD	R-HSA-9907570	6.864585e-01	0.163	0	0
Signaling by MST1	R-HSA-8852405	6.864585e-01	0.163	0	0
PKA-mediated phosphorylation of key metabolic factors	R-HSA-163358	6.864585e-01	0.163	0	0
Activation of caspases through apoptosome-mediated cleavage	R-HSA-111459	6.864585e-01	0.163	0	0
Synthesis of PS	R-HSA-1483101	6.864585e-01	0.163	0	0
PKB-mediated events	R-HSA-109703	6.864585e-01	0.163	0	0
PDE3B signalling	R-HSA-165160	6.864585e-01	0.163	0	0
Signalling to p38 via RIT and RIN	R-HSA-187706	6.864585e-01	0.163	0	0
SMAC, XIAP-regulated apoptotic response	R-HSA-111469	6.864585e-01	0.163	0	0
Epithelial-Mesenchymal Transition (EMT) during gastrulation	R-HSA-9758919	6.864585e-01	0.163	0	0
SLC15A4:TASL-dependent IRF5 activation	R-HSA-9860276	6.864585e-01	0.163	0	0
G alpha (z) signalling events	R-HSA-418597	6.917342e-01	0.160	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	6.922735e-01	0.160	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	6.926887e-01	0.159	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	6.941714e-01	0.159	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	6.941714e-01	0.159	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	6.994996e-01	0.155	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	7.016218e-01	0.154	0	0
BBSome-mediated cargo-targeting to cilium	R-HSA-5620922	7.016218e-01	0.154	0	0
Protein hydroxylation	R-HSA-9629569	7.016218e-01	0.154	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	7.034751e-01	0.153	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	7.034751e-01	0.153	0	0
Insulin processing	R-HSA-264876	7.034751e-01	0.153	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	7.048316e-01	0.152	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	7.048316e-01	0.152	0	0
Formation of axial mesoderm	R-HSA-9796292	7.053996e-01	0.152	0	0
IL-6-type cytokine receptor ligand interactions	R-HSA-6788467	7.053996e-01	0.152	0	0
Membrane binding and targetting of GAG proteins	R-HSA-174490	7.053996e-01	0.152	0	0
NoRC negatively regulates rRNA expression	R-HSA-427413	7.069078e-01	0.151	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	7.075273e-01	0.150	0	0
Signaling by NOTCH2	R-HSA-1980145	7.075273e-01	0.150	0	0
Signal amplification	R-HSA-392518	7.075273e-01	0.150	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	7.075273e-01	0.150	0	0
SARS-CoV-1 modulates host translation machinery	R-HSA-9735869	7.075273e-01	0.150	0	0
Detoxification of Reactive Oxygen Species	R-HSA-3299685	7.079513e-01	0.150	0	0
Post-translational protein phosphorylation	R-HSA-8957275	7.095985e-01	0.149	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	7.125449e-01	0.147	0	0
Signaling by Insulin receptor	R-HSA-74752	7.148782e-01	0.146	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	7.236006e-01	0.141	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	7.250193e-01	0.140	0	0
Formation of the Early Elongation Complex	R-HSA-113418	7.250193e-01	0.140	0	0
Activation of kainate receptors upon glutamate binding	R-HSA-451326	7.250193e-01	0.140	0	0
Inflammasomes	R-HSA-622312	7.250193e-01	0.140	0	0
Lagging Strand Synthesis	R-HSA-69186	7.262101e-01	0.139	0	0
MyD88 deficiency (TLR2/4)	R-HSA-5602498	7.262101e-01	0.139	0	0
NOTCH2 Activation and Transmission of Signal to the Nucleus	R-HSA-2979096	7.262101e-01	0.139	0	0
Basigin interactions	R-HSA-210991	7.262101e-01	0.139	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	7.268470e-01	0.139	0	0
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	7.273616e-01	0.138	0	0
PTK6 promotes HIF1A stabilization	R-HSA-8857538	7.287846e-01	0.137	0	0
RUNX1 regulates transcription of genes involved in WNT signaling	R-HSA-8939256	7.287846e-01	0.137	0	0
STAT5 Activation	R-HSA-9645135	7.287846e-01	0.137	0	0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD	R-HSA-9865125	7.287846e-01	0.137	0	0
Defective CHST14 causes EDS, musculocontractural type	R-HSA-3595174	7.287846e-01	0.137	0	0
Branched-chain ketoacid dehydrogenase kinase deficiency	R-HSA-9912481	7.287846e-01	0.137	0	0
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)	R-HSA-5619070	7.287846e-01	0.137	0	0
Defective CHST3 causes SEDCJD	R-HSA-3595172	7.287846e-01	0.137	0	0
H139Hfs13* PPM1K causes a mild variant of MSUD	R-HSA-9912529	7.287846e-01	0.137	0	0
Small interfering RNA (siRNA) biogenesis	R-HSA-426486	7.287846e-01	0.137	0	0
G2/M DNA replication checkpoint	R-HSA-69478	7.287846e-01	0.137	0	0
Abacavir transmembrane transport	R-HSA-2161517	7.287846e-01	0.137	0	0
CREB phosphorylation	R-HSA-199920	7.287846e-01	0.137	0	0
Activation of NIMA Kinases NEK9, NEK6, NEK7	R-HSA-2980767	7.287846e-01	0.137	1	1
HDL clearance	R-HSA-8964011	7.287846e-01	0.137	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	7.301459e-01	0.137	0	0
ABC-family proteins mediated transport	R-HSA-382556	7.334917e-01	0.135	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	7.342098e-01	0.134	0	0
Retrograde neurotrophin signalling	R-HSA-177504	7.345124e-01	0.134	0	0
HDL assembly	R-HSA-8963896	7.345124e-01	0.134	0	0
Synthesis And Processing Of GAG, GAGPOL Polyproteins	R-HSA-174495	7.345124e-01	0.134	0	0
Malate-aspartate shuttle	R-HSA-9856872	7.345124e-01	0.134	0	0
Glycerophospholipid catabolism	R-HSA-6814848	7.345124e-01	0.134	0	0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	R-HSA-975163	7.345124e-01	0.134	0	0
Ca2+ pathway	R-HSA-4086398	7.348260e-01	0.134	0	0
Dual incision in TC-NER	R-HSA-6782135	7.386766e-01	0.132	0	0
Ion channel transport	R-HSA-983712	7.428614e-01	0.129	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	7.452291e-01	0.128	0	0
mRNA Capping	R-HSA-72086	7.453751e-01	0.128	0	0
DARPP-32 events	R-HSA-180024	7.453751e-01	0.128	0	0
SARS-CoV-1 Infection	R-HSA-9678108	7.486460e-01	0.126	0	0
Signaling by WNT	R-HSA-195721	7.486912e-01	0.126	0	0
IRAK4 deficiency (TLR2/4)	R-HSA-5603041	7.491814e-01	0.125	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	7.491814e-01	0.125	0	0
Ribavirin ADME	R-HSA-9755088	7.491814e-01	0.125	0	0
Deadenylation-dependent mRNA decay	R-HSA-429914	7.531763e-01	0.123	0	0
Amino acid transport across the plasma membrane	R-HSA-352230	7.531763e-01	0.123	0	0
TCF dependent signaling in response to WNT	R-HSA-201681	7.540853e-01	0.123	0	0
SLC-mediated transport of amino acids	R-HSA-9958863	7.569422e-01	0.121	0	0
ER-Phagosome pathway	R-HSA-1236974	7.576059e-01	0.121	0	0
Toll-like Receptor Cascades	R-HSA-168898	7.593400e-01	0.120	0	0
Processive synthesis on the lagging strand	R-HSA-69183	7.611363e-01	0.119	0	0
TRAF6-mediated induction of TAK1 complex within TLR4 complex	R-HSA-937072	7.611363e-01	0.119	0	0
SHC1 events in EGFR signaling	R-HSA-180336	7.611363e-01	0.119	0	0
RNA Polymerase III Chain Elongation	R-HSA-73780	7.611363e-01	0.119	0	0
G beta:gamma signalling through BTK	R-HSA-8964315	7.611363e-01	0.119	0	0
Lysosphingolipid and LPA receptors	R-HSA-419408	7.611363e-01	0.119	0	0
DNA Damage Reversal	R-HSA-73942	7.611363e-01	0.119	0	0
Protein methylation	R-HSA-8876725	7.611363e-01	0.119	0	0
RMTs methylate histone arginines	R-HSA-3214858	7.630266e-01	0.117	0	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	7.645595e-01	0.117	0	0
GABA synthesis, release, reuptake and degradation	R-HSA-888590	7.645595e-01	0.117	0	0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	R-HSA-9931269	7.646680e-01	0.117	0	0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	R-HSA-2892245	7.653991e-01	0.116	0	0
Defective HLCS causes multiple carboxylase deficiency	R-HSA-3371599	7.653991e-01	0.116	0	0
PP2A-mediated dephosphorylation of key metabolic factors	R-HSA-163767	7.653991e-01	0.116	0	0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake	R-HSA-9031525	7.653991e-01	0.116	0	0
Defective CHSY1 causes TPBS	R-HSA-3595177	7.653991e-01	0.116	0	0
Pre-NOTCH Processing in the Endoplasmic Reticulum	R-HSA-1912399	7.653991e-01	0.116	0	0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose	R-HSA-9031528	7.653991e-01	0.116	0	0
SLBP independent Processing of Histone Pre-mRNAs	R-HSA-111367	7.653991e-01	0.116	0	0
RUNX1 regulates estrogen receptor mediated transcription	R-HSA-8931987	7.653991e-01	0.116	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	7.653991e-01	0.116	0	0
Insulin effects increased synthesis of Xylulose-5-Phosphate	R-HSA-163754	7.653991e-01	0.116	0	0
PTK6 Expression	R-HSA-8849473	7.653991e-01	0.116	0	0
Microbial modulation of RIPK1-mediated regulated necrosis	R-HSA-9686347	7.653991e-01	0.116	0	0
VLDL clearance	R-HSA-8964046	7.653991e-01	0.116	0	0
Nef Mediated CD4 Down-regulation	R-HSA-167590	7.653991e-01	0.116	0	0
TGFBR3 regulates TGF-beta signaling	R-HSA-9839389	7.653991e-01	0.116	0	0
tRNA processing	R-HSA-72306	7.687684e-01	0.114	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	7.705806e-01	0.113	0	0
Translation of Replicase and Assembly of the Replication Transcription Complex	R-HSA-9694676	7.705806e-01	0.113	0	0
Maternal to zygotic transition (MZT)	R-HSA-9816359	7.706589e-01	0.113	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	7.783151e-01	0.109	0	0
Regulation of PTEN stability and activity	R-HSA-8948751	7.789111e-01	0.109	0	0
Transcriptional regulation of pluripotent stem cells	R-HSA-452723	7.792120e-01	0.108	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	7.804490e-01	0.108	0	0
Respiratory syncytial virus (RSV) attachment and entry	R-HSA-9820960	7.825966e-01	0.106	0	0
Budding and maturation of HIV virion	R-HSA-162588	7.825966e-01	0.106	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	7.854125e-01	0.105	0	0
Regulation of BACH1 activity	R-HSA-9708530	7.854125e-01	0.105	0	0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	R-HSA-9634600	7.854125e-01	0.105	0	0
Differentiation of T cells	R-HSA-9945266	7.854125e-01	0.105	0	0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells)	R-HSA-9942503	7.854125e-01	0.105	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	7.854125e-01	0.105	0	0
Atorvastatin ADME	R-HSA-9754706	7.854125e-01	0.105	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	7.879892e-01	0.103	0	0
Interleukin receptor SHC signaling	R-HSA-912526	7.904624e-01	0.102	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	7.928479e-01	0.101	0	0
Stabilization of p53	R-HSA-69541	7.948415e-01	0.100	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	7.948415e-01	0.100	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	7.948415e-01	0.100	0	0
rRNA processing	R-HSA-72312	7.968664e-01	0.099	0	0
ALKBH3 mediated reversal of alkylation damage	R-HSA-112126	7.970724e-01	0.099	0	0
MET receptor recycling	R-HSA-8875656	7.970724e-01	0.099	0	0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	R-HSA-8939242	7.970724e-01	0.099	0	0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	R-HSA-77588	7.970724e-01	0.099	0	0
Interleukin-9 signaling	R-HSA-8985947	7.970724e-01	0.099	0	0
Regulation by c-FLIP	R-HSA-3371378	7.970724e-01	0.099	0	0
Fructose biosynthesis	R-HSA-5652227	7.970724e-01	0.099	0	0
Co-stimulation by ICOS	R-HSA-9927354	7.970724e-01	0.099	0	0
Activation of RAS in B cells	R-HSA-1169092	7.970724e-01	0.099	0	0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	R-HSA-111453	7.970724e-01	0.099	0	0
Neurotransmitter uptake and metabolism In glial cells	R-HSA-112313	7.970724e-01	0.099	0	0
Astrocytic Glutamate-Glutamine Uptake And Metabolism	R-HSA-210455	7.970724e-01	0.099	0	0
Dimerization of procaspase-8	R-HSA-69416	7.970724e-01	0.099	0	0
Modulation by Mtb of host immune system	R-HSA-9637628	7.970724e-01	0.099	0	0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	R-HSA-442729	7.970724e-01	0.099	0	0
G1/S DNA Damage Checkpoints	R-HSA-69615	8.054451e-01	0.094	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	8.066381e-01	0.093	0	0
Hemostasis	R-HSA-109582	8.074379e-01	0.093	0	0
Transcriptional regulation of testis differentiation	R-HSA-9690406	8.074895e-01	0.093	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	8.074895e-01	0.093	0	0
Regulation of T cell activation by CD28 family	R-HSA-388841	8.084956e-01	0.092	0	0
Translocation of ZAP-70 to Immunological synapse	R-HSA-202430	8.088887e-01	0.092	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	8.088887e-01	0.092	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	8.088887e-01	0.092	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	8.095893e-01	0.092	0	0
Attenuation phase	R-HSA-3371568	8.095893e-01	0.092	0	0
Transmission across Chemical Synapses	R-HSA-112315	8.123839e-01	0.090	0	0
Hedgehog 'off' state	R-HSA-5610787	8.135838e-01	0.090	0	0
Synthesis of DNA	R-HSA-69239	8.159652e-01	0.088	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	8.171067e-01	0.088	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	8.173004e-01	0.088	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	8.181120e-01	0.087	0	0
NGF-stimulated transcription	R-HSA-9031628	8.197015e-01	0.086	0	0
Gluconeogenesis	R-HSA-70263	8.197015e-01	0.086	0	0
Interleukin-21 signaling	R-HSA-9020958	8.244711e-01	0.084	0	0
CASP8 activity is inhibited	R-HSA-5218900	8.244711e-01	0.084	0	0
Defects in biotin (Btn) metabolism	R-HSA-3323169	8.244711e-01	0.084	0	0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	R-HSA-5649702	8.244711e-01	0.084	0	0
Caspase activation via Dependence Receptors in the absence of ligand	R-HSA-418889	8.244711e-01	0.084	0	0
mRNA Editing	R-HSA-75072	8.244711e-01	0.084	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	8.244711e-01	0.084	0	0
Regulation of signaling by NODAL	R-HSA-1433617	8.244711e-01	0.084	0	0
Regulation of NPAS4 gene transcription	R-HSA-9768777	8.244711e-01	0.084	0	0
Interleukin-1 processing	R-HSA-448706	8.244711e-01	0.084	0	0
Zinc influx into cells by the SLC39 gene family	R-HSA-442380	8.244711e-01	0.084	0	0
Antigen processing-Cross presentation	R-HSA-1236975	8.248016e-01	0.084	0	0
PI-3K cascade:FGFR2	R-HSA-5654695	8.259268e-01	0.083	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	8.259268e-01	0.083	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	8.259268e-01	0.083	0	0
PIWI-interacting RNA (piRNA) biogenesis	R-HSA-5601884	8.259268e-01	0.083	0	0
Laminin interactions	R-HSA-3000157	8.259268e-01	0.083	0	0
Tight junction interactions	R-HSA-420029	8.259268e-01	0.083	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	8.275186e-01	0.082	0	0
Modulation of host responses by IFN-stimulated genes	R-HSA-9909505	8.275186e-01	0.082	0	0
Switching of origins to a post-replicative state	R-HSA-69052	8.278810e-01	0.082	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	8.292433e-01	0.081	0	0
Glucagon signaling in metabolic regulation	R-HSA-163359	8.301511e-01	0.081	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	8.320563e-01	0.080	0	0
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	8.365376e-01	0.078	0	0
MET activates PTK2 signaling	R-HSA-8874081	8.416471e-01	0.075	0	0
TRP channels	R-HSA-3295583	8.416471e-01	0.075	0	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	8.416471e-01	0.075	0	0
Synthesis of IP2, IP, and Ins in the cytosol	R-HSA-1855183	8.416471e-01	0.075	0	0
Regulation of RAS by GAPs	R-HSA-5658442	8.437224e-01	0.074	0	0
Calnexin/calreticulin cycle	R-HSA-901042	8.439461e-01	0.074	0	0
NOD1/2 Signaling Pathway	R-HSA-168638	8.439461e-01	0.074	0	0
Cytosolic iron-sulfur cluster assembly	R-HSA-2564830	8.456503e-01	0.073	0	0
G beta:gamma signalling through PLC beta	R-HSA-418217	8.456503e-01	0.073	0	0
PKA activation in glucagon signalling	R-HSA-164378	8.456503e-01	0.073	0	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	8.456503e-01	0.073	0	0
PKA activation	R-HSA-163615	8.456503e-01	0.073	0	0
Presynaptic function of Kainate receptors	R-HSA-500657	8.456503e-01	0.073	0	0
Organic anion transport by SLC5/17/25 transporters	R-HSA-428643	8.456503e-01	0.073	0	0
Nephron development	R-HSA-9831926	8.456503e-01	0.073	0	0
TICAM1,TRAF6-dependent induction of TAK1 complex	R-HSA-9014325	8.481719e-01	0.072	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	8.481719e-01	0.072	0	0
Binding and entry of HIV virion	R-HSA-173107	8.481719e-01	0.072	0	0
Defective RIPK1-mediated regulated necrosis	R-HSA-9693928	8.481719e-01	0.072	0	0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	R-HSA-5140745	8.481719e-01	0.072	0	0
DNA replication initiation	R-HSA-68952	8.481719e-01	0.072	0	0
Ion influx/efflux at host-pathogen interface	R-HSA-6803544	8.481719e-01	0.072	0	0
Arachidonate production from DAG	R-HSA-426048	8.481719e-01	0.072	0	0
Cross-presentation of particulate exogenous antigens (phagosomes)	R-HSA-1236973	8.481719e-01	0.072	0	0
Receptor Mediated Mitophagy	R-HSA-8934903	8.481719e-01	0.072	0	0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	R-HSA-381676	8.487937e-01	0.071	0	0
Cytosolic tRNA aminoacylation	R-HSA-379716	8.487937e-01	0.071	0	0
Extension of Telomeres	R-HSA-180786	8.511109e-01	0.070	0	0
Phosphorylation of CD3 and TCR zeta chains	R-HSA-202427	8.561223e-01	0.067	0	0
ER Quality Control Compartment (ERQC)	R-HSA-901032	8.561223e-01	0.067	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	8.569969e-01	0.067	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	8.569969e-01	0.067	0	0
HCMV Infection	R-HSA-9609646	8.587373e-01	0.066	0	0
TBC/RABGAPs	R-HSA-8854214	8.602776e-01	0.065	0	0
Response of Mtb to phagocytosis	R-HSA-9637690	8.602776e-01	0.065	0	0
Circadian clock	R-HSA-9909396	8.604098e-01	0.065	0	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	8.610616e-01	0.065	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	8.610616e-01	0.065	0	0
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	8.610616e-01	0.065	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	8.610616e-01	0.065	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	8.610616e-01	0.065	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	8.610616e-01	0.065	0	0
Pre-NOTCH Processing in Golgi	R-HSA-1912420	8.620316e-01	0.064	0	0
Signaling by FGFR2 IIIa TM	R-HSA-8851708	8.620316e-01	0.064	0	0
Erythrocytes take up carbon dioxide and release oxygen	R-HSA-1237044	8.620316e-01	0.064	0	0
O2/CO2 exchange in erythrocytes	R-HSA-1480926	8.620316e-01	0.064	0	0
Parasitic Infection Pathways	R-HSA-9824443	8.632973e-01	0.064	0	0
Leishmania infection	R-HSA-9658195	8.632973e-01	0.064	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	8.650765e-01	0.063	0	0
Presynaptic depolarization and calcium channel opening	R-HSA-112308	8.686736e-01	0.061	0	0
Alpha-protein kinase 1 signaling pathway	R-HSA-9645460	8.686736e-01	0.061	0	0
Synthesis of PIPs at the ER membrane	R-HSA-1483248	8.686736e-01	0.061	0	0
vRNA Synthesis	R-HSA-192814	8.686736e-01	0.061	0	0
vRNP Assembly	R-HSA-192905	8.686736e-01	0.061	0	0
Activated NTRK3 signals through RAS	R-HSA-9034864	8.686736e-01	0.061	0	0
Transport of RCbl within the body	R-HSA-9758890	8.686736e-01	0.061	0	0
Inorganic anion exchange by SLC26 transporters	R-HSA-427601	8.686736e-01	0.061	0	0
SARS-CoV-2 modulates autophagy	R-HSA-9754560	8.686736e-01	0.061	0	0
Prostanoid ligand receptors	R-HSA-391908	8.686736e-01	0.061	0	0
Dissolution of Fibrin Clot	R-HSA-75205	8.686736e-01	0.061	0	0
PRC2 methylates histones and DNA	R-HSA-212300	8.687114e-01	0.061	0	0
Telomere Extension By Telomerase	R-HSA-171319	8.694256e-01	0.061	0	0
Amine ligand-binding receptors	R-HSA-375280	8.710211e-01	0.060	0	0
G1 Phase	R-HSA-69236	8.710211e-01	0.060	0	0
Cyclin D associated events in G1	R-HSA-69231	8.710211e-01	0.060	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	8.723291e-01	0.059	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	8.743537e-01	0.058	0	0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	8.748113e-01	0.058	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	8.760645e-01	0.057	0	0
Cyclin E associated events during G1/S transition	R-HSA-69202	8.760645e-01	0.057	0	0
Regulation of PD-L1(CD274) translation	R-HSA-9909620	8.768046e-01	0.057	0	0
Formation of ATP by chemiosmotic coupling	R-HSA-163210	8.768046e-01	0.057	0	0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	R-HSA-9609523	8.768046e-01	0.057	0	0
Common Pathway of Fibrin Clot Formation	R-HSA-140875	8.768046e-01	0.057	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	8.779271e-01	0.057	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	8.779778e-01	0.057	0	0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	8.788302e-01	0.056	0	0
p53-Independent G1/S DNA Damage Checkpoint	R-HSA-69613	8.810567e-01	0.055	0	0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	R-HSA-69601	8.810567e-01	0.055	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	8.816822e-01	0.055	0	0
DS-GAG biosynthesis	R-HSA-2022923	8.864080e-01	0.052	0	0
Proton-coupled monocarboxylate transport	R-HSA-433692	8.864080e-01	0.052	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	8.864080e-01	0.052	0	0
Sodium/Calcium exchangers	R-HSA-425561	8.864080e-01	0.052	0	0
Activated NTRK2 signals through RAS	R-HSA-9026519	8.864080e-01	0.052	0	0
Cellular response to starvation	R-HSA-9711097	8.876358e-01	0.052	0	0
PD-L1(CD274) glycosylation and translocation to plasma membrane	R-HSA-9931295	8.901049e-01	0.051	0	0
PKA-mediated phosphorylation of CREB	R-HSA-111931	8.901049e-01	0.051	0	0
Synthesis, secretion, and deacylation of Ghrelin	R-HSA-422085	8.901049e-01	0.051	0	0
Zygotic genome activation (ZGA)	R-HSA-9819196	8.901049e-01	0.051	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	8.904173e-01	0.050	0	0
Cell recruitment (pro-inflammatory response)	R-HSA-9664424	8.904173e-01	0.050	0	0
Purinergic signaling in leishmaniasis infection	R-HSA-9660826	8.904173e-01	0.050	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	8.918578e-01	0.050	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	8.925189e-01	0.049	0	0
Signaling by NOTCH3	R-HSA-9012852	8.925189e-01	0.049	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	8.964078e-01	0.047	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	8.972399e-01	0.047	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	8.989354e-01	0.046	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	8.991361e-01	0.046	0	0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	R-HSA-381771	8.994871e-01	0.046	0	0
Plasma lipoprotein clearance	R-HSA-8964043	8.994871e-01	0.046	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	9.005420e-01	0.045	1	0
Maple Syrup Urine Disease	R-HSA-9865114	9.017484e-01	0.045	0	0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex	R-HSA-9931530	9.017484e-01	0.045	0	0
Serotonin clearance from the synaptic cleft	R-HSA-380615	9.017484e-01	0.045	0	0
Trafficking and processing of endosomal TLR	R-HSA-1679131	9.017484e-01	0.045	0	0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	R-HSA-975144	9.017484e-01	0.045	0	0
IRAK1 recruits IKK complex	R-HSA-937039	9.017484e-01	0.045	0	0
Erythrocytes take up oxygen and release carbon dioxide	R-HSA-1247673	9.017484e-01	0.045	0	0
Diseases associated with surfactant metabolism	R-HSA-5687613	9.017484e-01	0.045	0	0
OAS antiviral response	R-HSA-8983711	9.017484e-01	0.045	0	0
FRS-mediated FGFR3 signaling	R-HSA-5654706	9.020607e-01	0.045	0	0
Assembly Of The HIV Virion	R-HSA-175474	9.020607e-01	0.045	0	0
Serine metabolism	R-HSA-977347	9.020607e-01	0.045	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	9.029064e-01	0.044	0	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	9.030276e-01	0.044	0	0
Cargo concentration in the ER	R-HSA-5694530	9.030276e-01	0.044	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	9.049913e-01	0.043	0	0
GPER1 signaling	R-HSA-9634597	9.072461e-01	0.042	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	9.082307e-01	0.042	0	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	9.082307e-01	0.042	0	0
Interleukin-2 family signaling	R-HSA-451927	9.082307e-01	0.042	0	0
Negative regulation of NOTCH4 signaling	R-HSA-9604323	9.082307e-01	0.042	0	0
Regulation of IFNA/IFNB signaling	R-HSA-912694	9.127925e-01	0.040	0	0
FRS-mediated FGFR4 signaling	R-HSA-5654712	9.127925e-01	0.040	0	0
Fructose metabolism	R-HSA-5652084	9.127925e-01	0.040	0	0
Ethanol oxidation	R-HSA-71384	9.127925e-01	0.040	0	0
LDL clearance	R-HSA-8964038	9.127925e-01	0.040	0	0
p53-Dependent G1 DNA Damage Response	R-HSA-69563	9.147799e-01	0.039	0	0
p53-Dependent G1/S DNA damage checkpoint	R-HSA-69580	9.147799e-01	0.039	0	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	9.147799e-01	0.039	0	0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)	R-HSA-8877330	9.150179e-01	0.039	0	0
Adenylate cyclase activating pathway	R-HSA-170660	9.150179e-01	0.039	0	0
CREB1 phosphorylation through the activation of Adenylate Cyclase	R-HSA-442720	9.150179e-01	0.039	0	0
Processing of SMDT1	R-HSA-8949664	9.150179e-01	0.039	0	0
Diseases of nucleotide metabolism	R-HSA-9735804	9.150179e-01	0.039	0	0
PI5P Regulates TP53 Acetylation	R-HSA-6811555	9.150179e-01	0.039	0	0
NFE2L2 regulating tumorigenic genes	R-HSA-9818030	9.150179e-01	0.039	0	0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	R-HSA-9029569	9.150535e-01	0.039	0	0
Signaling by NOTCH1	R-HSA-1980143	9.184192e-01	0.037	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	9.202590e-01	0.036	0	0
Regulation of necroptotic cell death	R-HSA-5675482	9.208660e-01	0.036	0	0
ABC transporters in lipid homeostasis	R-HSA-1369062	9.224128e-01	0.035	0	0
Carnitine shuttle	R-HSA-200425	9.224128e-01	0.035	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	9.241099e-01	0.034	0	0
Removal of the Flap Intermediate	R-HSA-69166	9.264959e-01	0.033	0	0
Phospholipase C-mediated cascade; FGFR3	R-HSA-5654227	9.264959e-01	0.033	0	0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV	R-HSA-9859138	9.264959e-01	0.033	0	0
Hydrolysis of LPC	R-HSA-1483115	9.264959e-01	0.033	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	9.264959e-01	0.033	0	0
cGMP effects	R-HSA-418457	9.264959e-01	0.033	0	0
Formation of the active cofactor, UDP-glucuronate	R-HSA-173599	9.264959e-01	0.033	0	0
Physiological factors	R-HSA-5578768	9.264959e-01	0.033	0	0
Respiratory syncytial virus genome transcription	R-HSA-9828642	9.264959e-01	0.033	0	0
Acyl chain remodeling of CL	R-HSA-1482798	9.264959e-01	0.033	0	0
P2Y receptors	R-HSA-417957	9.264959e-01	0.033	0	0
Zinc transporters	R-HSA-435354	9.264959e-01	0.033	0	0
tRNA Aminoacylation	R-HSA-379724	9.276850e-01	0.033	0	0
SLC transporter disorders	R-HSA-5619102	9.278011e-01	0.033	0	0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane	R-HSA-9768727	9.286114e-01	0.032	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	9.286114e-01	0.032	0	0
Miscellaneous transport and binding events	R-HSA-5223345	9.286114e-01	0.032	0	0
Integration of energy metabolism	R-HSA-163685	9.290504e-01	0.032	0	0
Integrin cell surface interactions	R-HSA-216083	9.294540e-01	0.032	0	0
Incretin synthesis, secretion, and inactivation	R-HSA-400508	9.305384e-01	0.031	0	0
Replacement of protamines by nucleosomes in the male pronucleus	R-HSA-9821993	9.310260e-01	0.031	0	0
Plasma lipoprotein assembly	R-HSA-8963898	9.310260e-01	0.031	0	0
Mitochondrial RNA degradation	R-HSA-9836573	9.310260e-01	0.031	0	0
DNA Replication Pre-Initiation	R-HSA-69002	9.334361e-01	0.030	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	9.342415e-01	0.030	0	0
Autodegradation of the E3 ubiquitin ligase COP1	R-HSA-349425	9.356542e-01	0.029	0	0
Adenylate cyclase inhibitory pathway	R-HSA-170670	9.364242e-01	0.029	0	0
Phospholipase C-mediated cascade; FGFR4	R-HSA-5654228	9.364242e-01	0.029	0	0
Translesion synthesis by REV1	R-HSA-110312	9.364242e-01	0.029	0	0
Telomere C-strand synthesis initiation	R-HSA-174430	9.364242e-01	0.029	0	0
Biotin transport and metabolism	R-HSA-196780	9.364242e-01	0.029	0	0
Protein repair	R-HSA-5676934	9.364242e-01	0.029	0	0
Protein lipoylation	R-HSA-9857492	9.364242e-01	0.029	0	0
Other semaphorin interactions	R-HSA-416700	9.364242e-01	0.029	0	0
Ribosome-associated quality control	R-HSA-9948299	9.366431e-01	0.028	0	0
Adipogenesis	R-HSA-9843745	9.374911e-01	0.028	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	9.375382e-01	0.028	0	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	9.386309e-01	0.028	1	0
FRS-mediated FGFR1 signaling	R-HSA-5654693	9.387287e-01	0.027	0	0
Hyaluronan degradation	R-HSA-2160916	9.387287e-01	0.027	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.397838e-01	0.027	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	9.397838e-01	0.027	1	1
Regulation of Apoptosis	R-HSA-169911	9.420502e-01	0.026	0	0
Surfactant metabolism	R-HSA-5683826	9.425554e-01	0.026	0	0
Neutrophil degranulation	R-HSA-6798695	9.440395e-01	0.025	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	9.449021e-01	0.025	0	0
Translesion synthesis by POLI	R-HSA-5656121	9.450120e-01	0.025	0	0
Entry of Influenza Virion into Host Cell via Endocytosis	R-HSA-168275	9.450120e-01	0.025	0	0
Defective GALNT3 causes HFTC	R-HSA-5083625	9.450120e-01	0.025	0	0
Defective GALNT12 causes CRCS1	R-HSA-5083636	9.450120e-01	0.025	0	0
Phase 4 - resting membrane potential	R-HSA-5576886	9.450120e-01	0.025	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	9.450120e-01	0.025	0	0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	R-HSA-434316	9.450120e-01	0.025	0	0
Fructose catabolism	R-HSA-70350	9.450120e-01	0.025	0	0
Attachment and Entry	R-HSA-9678110	9.450120e-01	0.025	0	0
Adrenaline,noradrenaline inhibits insulin secretion	R-HSA-400042	9.456095e-01	0.024	0	0
Sphingolipid catabolism	R-HSA-9845614	9.456095e-01	0.024	0	0
Defective CFTR causes cystic fibrosis	R-HSA-5678895	9.478233e-01	0.023	0	0
Vasopressin regulates renal water homeostasis via Aquaporins	R-HSA-432040	9.478233e-01	0.023	0	0
Glycosphingolipid transport	R-HSA-9845576	9.478520e-01	0.023	0	0
Formation of Fibrin Clot (Clotting Cascade)	R-HSA-140877	9.478520e-01	0.023	0	0
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	9.482642e-01	0.023	0	0
Gastrulation	R-HSA-9758941	9.489434e-01	0.023	0	0
Telomere Maintenance	R-HSA-157579	9.492919e-01	0.023	0	0
Neuronal System	R-HSA-112316	9.502712e-01	0.022	0	0
Cristae formation	R-HSA-8949613	9.517499e-01	0.021	0	0
Signaling by BMP	R-HSA-201451	9.517499e-01	0.021	0	0
Synthesis of PE	R-HSA-1483213	9.517499e-01	0.021	0	0
Maturation of hRSV A proteins	R-HSA-9828806	9.517499e-01	0.021	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	9.519729e-01	0.021	0	0
Pre-NOTCH Transcription and Translation	R-HSA-1912408	9.519729e-01	0.021	0	0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	R-HSA-2892247	9.524402e-01	0.021	0	0
Translesion synthesis by POLK	R-HSA-5655862	9.524402e-01	0.021	0	0
Antigen processing: Ub, ATP-independent proteasomal degradation	R-HSA-9912633	9.524402e-01	0.021	0	0
Defective B4GALT7 causes EDS, progeroid type	R-HSA-3560783	9.524402e-01	0.021	0	0
Defective B3GALT6 causes EDSP2 and SEMDJL1	R-HSA-4420332	9.524402e-01	0.021	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	9.524402e-01	0.021	0	0
Phase 2 - plateau phase	R-HSA-5576893	9.524402e-01	0.021	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	9.524402e-01	0.021	0	0
Fibronectin matrix formation	R-HSA-1566977	9.524402e-01	0.021	0	0
STAT5 activation downstream of FLT3 ITD mutants	R-HSA-9702518	9.524402e-01	0.021	0	0
Synthesis of PG	R-HSA-1483148	9.524402e-01	0.021	0	0
Galactose catabolism	R-HSA-70370	9.524402e-01	0.021	0	0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	R-HSA-400511	9.524402e-01	0.021	0	0
Regulation of innate immune responses to cytosolic DNA	R-HSA-3134975	9.524402e-01	0.021	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	9.526448e-01	0.021	1	1
Degradation of AXIN	R-HSA-4641257	9.531089e-01	0.021	0	0
Degradation of DVL	R-HSA-4641258	9.531089e-01	0.021	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	9.551270e-01	0.020	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.561934e-01	0.019	0	0
Co-inhibition by PD-1	R-HSA-389948	9.565037e-01	0.019	0	0
Synthesis of PC	R-HSA-1483191	9.570530e-01	0.019	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	9.572244e-01	0.019	0	0
Insulin receptor recycling	R-HSA-77387	9.572244e-01	0.019	0	0
FRS-mediated FGFR2 signaling	R-HSA-5654700	9.572244e-01	0.019	0	0
RIPK1-mediated regulated necrosis	R-HSA-5213460	9.578671e-01	0.019	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	9.578671e-01	0.019	0	0
Elastic fibre formation	R-HSA-1566948	9.578671e-01	0.019	0	0
Eukaryotic Translation Elongation	R-HSA-156842	9.585989e-01	0.018	0	0
Phospholipase C-mediated cascade: FGFR1	R-HSA-5654219	9.588653e-01	0.018	0	0
Defective B3GAT3 causes JDSSDHD	R-HSA-3560801	9.588653e-01	0.018	0	0
Defective C1GALT1C1 causes TNPS	R-HSA-5083632	9.588653e-01	0.018	0	0
Regulation of NPAS4 gene expression	R-HSA-9768759	9.588653e-01	0.018	0	0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se	R-HSA-2408550	9.588653e-01	0.018	0	0
Kidney development	R-HSA-9830369	9.598049e-01	0.018	0	0
Metal ion SLC transporters	R-HSA-425410	9.610792e-01	0.017	0	0
Signaling by Hedgehog	R-HSA-5358351	9.615143e-01	0.017	0	0
Assembly of the pre-replicative complex	R-HSA-68867	9.615953e-01	0.017	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	9.619121e-01	0.017	0	0
DNA methylation	R-HSA-5334118	9.621007e-01	0.017	0	0
Glucagon-type ligand receptors	R-HSA-420092	9.621007e-01	0.017	0	0
Nitric oxide stimulates guanylate cyclase	R-HSA-392154	9.621007e-01	0.017	0	0
GSK3B-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929356	9.621695e-01	0.017	0	0
PPARA activates gene expression	R-HSA-1989781	9.641276e-01	0.016	0	0
Nucleotide-like (purinergic) receptors	R-HSA-418038	9.644227e-01	0.016	0	0
Vitamin D (calciferol) metabolism	R-HSA-196791	9.644227e-01	0.016	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	9.647501e-01	0.016	0	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	9.664406e-01	0.015	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	9.664406e-01	0.015	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	9.670110e-01	0.015	0	0
Azathioprine ADME	R-HSA-9748787	9.681019e-01	0.014	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	9.690725e-01	0.014	0	0
Prostacyclin signalling through prostacyclin receptor	R-HSA-392851	9.692296e-01	0.014	0	0
Strand-asynchronous mitochondrial DNA replication	R-HSA-9913635	9.692296e-01	0.014	0	0
Pyrimidine biosynthesis	R-HSA-500753	9.692296e-01	0.014	0	0
Methionine salvage pathway	R-HSA-1237112	9.692296e-01	0.014	0	0
SPOP-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929491	9.695633e-01	0.013	0	0
NIK-->noncanonical NF-kB signaling	R-HSA-5676590	9.695633e-01	0.013	0	0
Hh mutants are degraded by ERAD	R-HSA-5362768	9.695633e-01	0.013	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	9.695633e-01	0.013	0	0
Peptide chain elongation	R-HSA-156902	9.697562e-01	0.013	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	9.701076e-01	0.013	0	0
Regulation of activated PAK-2p34 by proteasome mediated degradation	R-HSA-211733	9.702999e-01	0.013	0	0
Molecules associated with elastic fibres	R-HSA-2129379	9.702999e-01	0.013	0	0
Regulation of mitotic cell cycle	R-HSA-453276	9.716962e-01	0.012	1	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	9.716962e-01	0.012	1	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	9.727257e-01	0.012	0	0
GLI3 is processed to GLI3R by the proteasome	R-HSA-5610785	9.727257e-01	0.012	0	0
Degradation of GLI2 by the proteasome	R-HSA-5610783	9.727257e-01	0.012	0	0
Translation of Structural Proteins	R-HSA-9683701	9.727257e-01	0.012	0	0
Phospholipase C-mediated cascade; FGFR2	R-HSA-5654221	9.733872e-01	0.012	0	0
Creatine metabolism	R-HSA-71288	9.733872e-01	0.012	0	0
Acyl chain remodelling of PI	R-HSA-1482922	9.733872e-01	0.012	0	0
Pregnenolone biosynthesis	R-HSA-196108	9.733872e-01	0.012	0	0
Eicosanoid ligand-binding receptors	R-HSA-391903	9.733872e-01	0.012	0	0
Mitochondrial protein import	R-HSA-1268020	9.736213e-01	0.012	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	9.736213e-01	0.012	0	0
Orc1 removal from chromatin	R-HSA-68949	9.739273e-01	0.011	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	9.744595e-01	0.011	0	0
Interleukin-1 family signaling	R-HSA-446652	9.744595e-01	0.011	0	0
Platelet homeostasis	R-HSA-418346	9.756193e-01	0.011	0	0
Regulation of insulin secretion	R-HSA-422356	9.758233e-01	0.011	0	0
DNA Replication	R-HSA-69306	9.760456e-01	0.011	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	9.764581e-01	0.010	0	0
Cardiogenesis	R-HSA-9733709	9.767745e-01	0.010	0	0
G-protein activation	R-HSA-202040	9.769833e-01	0.010	0	0
ADP signalling through P2Y purinoceptor 12	R-HSA-392170	9.769833e-01	0.010	0	0
Matriglycan biosynthesis on DAG1	R-HSA-9939291	9.769833e-01	0.010	0	0
SHC-mediated cascade:FGFR3	R-HSA-5654704	9.769833e-01	0.010	0	0
Intrinsic Pathway of Fibrin Clot Formation	R-HSA-140837	9.769833e-01	0.010	0	0
Vitamin C (ascorbate) metabolism	R-HSA-196836	9.769833e-01	0.010	0	0
Acyl chain remodelling of PG	R-HSA-1482925	9.769833e-01	0.010	0	0
Hh mutants abrogate ligand secretion	R-HSA-5387390	9.781393e-01	0.010	0	0
Defective pyroptosis	R-HSA-9710421	9.781393e-01	0.010	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	9.781741e-01	0.010	0	0
Formation of the cornified envelope	R-HSA-6809371	9.790406e-01	0.009	0	0
Viral Infection Pathways	R-HSA-9824446	9.793226e-01	0.009	0	0
Acyl chain remodelling of PC	R-HSA-1482788	9.794766e-01	0.009	0	0
Vitamin B5 (pantothenate) metabolism	R-HSA-199220	9.794766e-01	0.009	0	0
Phospholipid metabolism	R-HSA-1483257	9.796692e-01	0.009	0	0
CS-GAG biosynthesis	R-HSA-2022870	9.800937e-01	0.009	0	0
SHC-mediated cascade:FGFR4	R-HSA-5654719	9.800937e-01	0.009	0	0
Metabolism of Angiotensinogen to Angiotensins	R-HSA-2022377	9.800937e-01	0.009	0	0
Attachment and Entry	R-HSA-9694614	9.800937e-01	0.009	0	0
Developmental Lineage of Mammary Gland Alveolar Cells	R-HSA-9927426	9.818727e-01	0.008	0	0
Glycosaminoglycan-protein linkage region biosynthesis	R-HSA-1971475	9.818727e-01	0.008	0	0
Regulation of TLR by endogenous ligand	R-HSA-5686938	9.818727e-01	0.008	0	0
eNOS activation	R-HSA-203615	9.818727e-01	0.008	0	0
Ubiquitin-dependent degradation of Cyclin D	R-HSA-75815	9.818727e-01	0.008	0	0
Hyaluronan metabolism	R-HSA-2142845	9.818727e-01	0.008	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	9.818727e-01	0.008	0	0
Dectin-1 mediated noncanonical NF-kB signaling	R-HSA-5607761	9.825191e-01	0.008	0	0
ADORA2B mediated anti-inflammatory cytokines production	R-HSA-9660821	9.825191e-01	0.008	0	0
Translation of Structural Proteins	R-HSA-9694635	9.835801e-01	0.007	0	0
Transferrin endocytosis and recycling	R-HSA-917977	9.839962e-01	0.007	0	0
Acyl chain remodelling of PE	R-HSA-1482839	9.839962e-01	0.007	0	0
Inactivation, recovery and regulation of the phototransduction cascade	R-HSA-2514859	9.843809e-01	0.007	0	0
ABC transporter disorders	R-HSA-5619084	9.850345e-01	0.007	0	0
Termination of O-glycan biosynthesis	R-HSA-977068	9.851106e-01	0.007	0	0
Interleukin-20 family signaling	R-HSA-8854691	9.851106e-01	0.007	0	0
Free fatty acids regulate insulin secretion	R-HSA-400451	9.851106e-01	0.007	0	0
Formation of the ureteric bud	R-HSA-9830674	9.851106e-01	0.007	0	0
Synthesis of UDP-N-acetyl-glucosamine	R-HSA-446210	9.851106e-01	0.007	0	0
Synthesis of pyrophosphates in the cytosol	R-HSA-1855167	9.851106e-01	0.007	0	0
Mitochondrial mRNA modification	R-HSA-9937008	9.851106e-01	0.007	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	9.856592e-01	0.006	0	0
Eukaryotic Translation Termination	R-HSA-72764	9.856592e-01	0.006	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	9.858475e-01	0.006	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	9.858770e-01	0.006	0	0
Vif-mediated degradation of APOBEC3G	R-HSA-180585	9.858770e-01	0.006	0	0
Triglyceride catabolism	R-HSA-163560	9.858770e-01	0.006	0	0
FGFR2 mutant receptor activation	R-HSA-1839126	9.858770e-01	0.006	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	9.859696e-01	0.006	0	0
RSV-host interactions	R-HSA-9833110	9.862489e-01	0.006	0	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	9.868350e-01	0.006	0	0
Thromboxane signalling through TP receptor	R-HSA-428930	9.871230e-01	0.006	0	0
SHC-mediated cascade:FGFR1	R-HSA-5654688	9.871230e-01	0.006	0	0
Assembly of active LPL and LIPC lipase complexes	R-HSA-8963889	9.871230e-01	0.006	0	0
TNFs bind their physiological receptors	R-HSA-5669034	9.871230e-01	0.006	0	0
Neddylation	R-HSA-8951664	9.873374e-01	0.006	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	9.875419e-01	0.005	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	9.875419e-01	0.005	0	0
Disorders of transmembrane transporters	R-HSA-5619115	9.878488e-01	0.005	0	0
COPII-mediated vesicle transport	R-HSA-204005	9.878704e-01	0.005	0	0
Downstream TCR signaling	R-HSA-202424	9.887055e-01	0.005	0	0
Neurotransmitter release cycle	R-HSA-112310	9.887055e-01	0.005	0	0
Base Excision Repair	R-HSA-73884	9.887055e-01	0.005	0	0
Activation of G protein gated Potassium channels	R-HSA-1296041	9.888635e-01	0.005	0	0
G protein gated Potassium channels	R-HSA-1296059	9.888635e-01	0.005	0	0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	R-HSA-997272	9.888635e-01	0.005	0	0
Chemokine receptors bind chemokines	R-HSA-380108	9.888934e-01	0.005	0	0
tRNA processing in the mitochondrion	R-HSA-6785470	9.890148e-01	0.005	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.897370e-01	0.004	0	0
Aquaporin-mediated transport	R-HSA-445717	9.897846e-01	0.004	0	0
HCMV Late Events	R-HSA-9610379	9.899070e-01	0.004	0	0
Stimuli-sensing channels	R-HSA-2672351	9.901466e-01	0.004	0	0
RAS processing	R-HSA-9648002	9.903173e-01	0.004	0	0
Diseases of branched-chain amino acid catabolism	R-HSA-9865118	9.903689e-01	0.004	0	0
Urea cycle	R-HSA-70635	9.903689e-01	0.004	0	0
Abacavir ADME	R-HSA-2161522	9.903689e-01	0.004	0	0
Cytoprotection by HMOX1	R-HSA-9707564	9.906616e-01	0.004	0	0
Activation of NF-kappaB in B cells	R-HSA-1169091	9.911731e-01	0.004	0	0
Hedgehog ligand biogenesis	R-HSA-5358346	9.911731e-01	0.004	0	0
The phototransduction cascade	R-HSA-2514856	9.911731e-01	0.004	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	9.914052e-01	0.004	0	0
rRNA processing in the mitochondrion	R-HSA-8868766	9.914685e-01	0.004	0	0
Mitochondrial tRNA aminoacylation	R-HSA-379726	9.914685e-01	0.004	0	0
Interleukin-1 signaling	R-HSA-9020702	9.914793e-01	0.004	0	0
Selenocysteine synthesis	R-HSA-2408557	9.914793e-01	0.004	0	0
Packaging Of Telomere Ends	R-HSA-171306	9.916708e-01	0.004	0	0
RNA Polymerase I Promoter Opening	R-HSA-73728	9.916708e-01	0.004	0	0
SHC-mediated cascade:FGFR2	R-HSA-5654699	9.916708e-01	0.004	0	0
Triglyceride biosynthesis	R-HSA-75109	9.916708e-01	0.004	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	9.921364e-01	0.003	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	9.921364e-01	0.003	0	0
Iron uptake and transport	R-HSA-917937	9.926655e-01	0.003	0	0
Prednisone ADME	R-HSA-9757110	9.927968e-01	0.003	0	0
Iron assimilation using enterobactin	R-HSA-9638334	9.927968e-01	0.003	0	0
Pyrimidine salvage	R-HSA-73614	9.927968e-01	0.003	0	0
Pyroptosis	R-HSA-5620971	9.927968e-01	0.003	0	0
Viral mRNA Translation	R-HSA-192823	9.928638e-01	0.003	0	0
Translation	R-HSA-72766	9.929665e-01	0.003	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.929913e-01	0.003	0	0
Degradation of CRY and PER proteins	R-HSA-9932298	9.933834e-01	0.003	0	0
SLC-mediated transport of neurotransmitters	R-HSA-442660	9.933834e-01	0.003	0	0
Activation of GABAB receptors	R-HSA-991365	9.941761e-01	0.003	0	0
GABA B receptor activation	R-HSA-977444	9.941761e-01	0.003	0	0
Paracetamol ADME	R-HSA-9753281	9.944546e-01	0.002	0	0
Neurotransmitter clearance	R-HSA-112311	9.946129e-01	0.002	0	0
Immune System	R-HSA-168256	9.948641e-01	0.002	0	0
Regulated Necrosis	R-HSA-5218859	9.952106e-01	0.002	0	0
Aspartate and asparagine metabolism	R-HSA-8963693	9.953413e-01	0.002	0	0
G alpha (q) signalling events	R-HSA-416476	9.956091e-01	0.002	0	0
Dectin-2 family	R-HSA-5621480	9.956155e-01	0.002	0	0
Inwardly rectifying K+ channels	R-HSA-1296065	9.959713e-01	0.002	0	0
Regulation of ornithine decarboxylase (ODC)	R-HSA-350562	9.959713e-01	0.002	0	0
DAG1 glycosylations	R-HSA-8931838	9.959713e-01	0.002	0	0
Recognition and association of DNA glycosylase with site containing an affected purine	R-HSA-110330	9.959713e-01	0.002	0	0
Somitogenesis	R-HSA-9824272	9.960357e-01	0.002	0	0
Signaling by NOTCH	R-HSA-157118	9.961598e-01	0.002	0	0
Peptide hormone metabolism	R-HSA-2980736	9.962023e-01	0.002	0	0
FCGR3A-mediated IL10 synthesis	R-HSA-9664323	9.962464e-01	0.002	0	0
Assembly of the ORC complex at the origin of replication	R-HSA-68616	9.965161e-01	0.002	0	0
Diseases associated with glycosylation precursor biosynthesis	R-HSA-5609975	9.965161e-01	0.002	0	0
Recycling of bile acids and salts	R-HSA-159418	9.965161e-01	0.002	0	0
Peroxisomal protein import	R-HSA-9033241	9.965388e-01	0.002	0	0
Triglyceride metabolism	R-HSA-8979227	9.965388e-01	0.002	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	9.965388e-01	0.002	0	0
ECM proteoglycans	R-HSA-3000178	9.965610e-01	0.001	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	9.968269e-01	0.001	0	0
RAB geranylgeranylation	R-HSA-8873719	9.969264e-01	0.001	0	0
CS/DS degradation	R-HSA-2024101	9.969872e-01	0.001	0	0
Vpu mediated degradation of CD4	R-HSA-180534	9.969872e-01	0.001	0	0
Heme degradation	R-HSA-189483	9.969872e-01	0.001	0	0
Formation of paraxial mesoderm	R-HSA-9793380	9.972716e-01	0.001	0	0
Phosphate bond hydrolysis by NUDT proteins	R-HSA-2393930	9.973947e-01	0.001	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	9.973947e-01	0.001	0	0
Mitochondrial protein degradation	R-HSA-9837999	9.974068e-01	0.001	0	0
Glyoxylate metabolism and glycine degradation	R-HSA-389661	9.976358e-01	0.001	0	0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	R-HSA-8854050	9.977470e-01	0.001	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	9.977470e-01	0.001	0	0
Defects in vitamin and cofactor metabolism	R-HSA-3296482	9.977470e-01	0.001	0	0
HS-GAG biosynthesis	R-HSA-2022928	9.980518e-01	0.001	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	9.981770e-01	0.001	0	0
Branched-chain amino acid catabolism	R-HSA-70895	9.981770e-01	0.001	0	0
Interferon alpha/beta signaling	R-HSA-909733	9.982113e-01	0.001	0	0
SIRT1 negatively regulates rRNA expression	R-HSA-427359	9.983153e-01	0.001	0	0
Cleavage of the damaged purine	R-HSA-110331	9.983153e-01	0.001	0	0
NCAM1 interactions	R-HSA-419037	9.983153e-01	0.001	0	0
SLC-mediated transport of organic cations	R-HSA-549127	9.983153e-01	0.001	0	0
Metabolism of folate and pterines	R-HSA-196757	9.983153e-01	0.001	0	0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	9.983211e-01	0.001	0	0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	9.983211e-01	0.001	0	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	9.983211e-01	0.001	0	0
Uptake and actions of bacterial toxins	R-HSA-5339562	9.983998e-01	0.001	0	0
Protein localization	R-HSA-9609507	9.984622e-01	0.001	0	0
Depurination	R-HSA-73927	9.985432e-01	0.001	0	0
Purine salvage	R-HSA-74217	9.985432e-01	0.001	0	0
Nucleotide biosynthesis	R-HSA-8956320	9.985957e-01	0.001	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	9.986531e-01	0.001	0	0
Leishmania parasite growth and survival	R-HSA-9664433	9.986531e-01	0.001	0	0
Cross-presentation of soluble exogenous antigens (endosomes)	R-HSA-1236978	9.987403e-01	0.001	0	0
Pentose phosphate pathway	R-HSA-71336	9.987403e-01	0.001	0	0
Amyloid fiber formation	R-HSA-977225	9.988878e-01	0.000	0	0
Tryptophan catabolism	R-HSA-71240	9.989107e-01	0.000	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	9.990581e-01	0.000	0	0
Maturation of spike protein	R-HSA-9694548	9.990581e-01	0.000	0	0
Purine ribonucleoside monophosphate biosynthesis	R-HSA-73817	9.990581e-01	0.000	0	0
Mitochondrial ribosome-associated quality control	R-HSA-9937383	9.990758e-01	0.000	0	0
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	9.991162e-01	0.000	0	0
FCGR activation	R-HSA-2029481	9.991199e-01	0.000	0	0
Synthesis of PA	R-HSA-1483166	9.991689e-01	0.000	0	0
Scavenging by Class A Receptors	R-HSA-3000480	9.991855e-01	0.000	0	0
Hedgehog 'on' state	R-HSA-5632684	9.991857e-01	0.000	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	9.992957e-01	0.000	0	0
Depyrimidination	R-HSA-73928	9.992957e-01	0.000	0	0
Cell surface interactions at the vascular wall	R-HSA-202733	9.992994e-01	0.000	0	0
Aspirin ADME	R-HSA-9749641	9.993629e-01	0.000	0	0
Selenoamino acid metabolism	R-HSA-2408522	9.994098e-01	0.000	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.994366e-01	0.000	0	0
GABA receptor activation	R-HSA-977443	9.994404e-01	0.000	0	0
Proteasome assembly	R-HSA-9907900	9.994735e-01	0.000	0	0
SCF(Skp2)-mediated degradation of p27/p21	R-HSA-187577	9.994735e-01	0.000	0	0
Cobalamin (Cbl, vitamin B12) transport and metabolism	R-HSA-196741	9.994735e-01	0.000	0	0
Synthesis of Leukotrienes (LT) and Eoxins (EX)	R-HSA-2142691	9.994735e-01	0.000	0	0
Nucleotide salvage	R-HSA-8956321	9.995097e-01	0.000	0	0
Diseases associated with glycosaminoglycan metabolism	R-HSA-3560782	9.995447e-01	0.000	0	0
Interleukin-10 signaling	R-HSA-6783783	9.996565e-01	0.000	0	0
SLC-mediated transport of organic anions	R-HSA-9955298	9.996565e-01	0.000	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	9.996967e-01	0.000	0	0
Plasma lipoprotein remodeling	R-HSA-8963899	9.997057e-01	0.000	0	0
Cellular response to hypoxia	R-HSA-1234174	9.997116e-01	0.000	0	0
G alpha (s) signalling events	R-HSA-418555	9.997126e-01	0.000	0	0
Post-translational protein modification	R-HSA-597592	9.997577e-01	0.000	0	0
Nicotinate metabolism	R-HSA-196807	9.997791e-01	0.000	0	0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	R-HSA-2162123	9.997800e-01	0.000	0	0
Complex IV assembly	R-HSA-9864848	9.998098e-01	0.000	0	0
Cytosolic sulfonation of small molecules	R-HSA-156584	9.998098e-01	0.000	0	0
Peptide ligand-binding receptors	R-HSA-375276	9.998134e-01	0.000	0	0
Extracellular matrix organization	R-HSA-1474244	9.998419e-01	0.000	0	0
Asparagine N-linked glycosylation	R-HSA-446203	9.998628e-01	0.000	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.998652e-01	0.000	0	0
Diseases associated with O-glycosylation of proteins	R-HSA-3906995	9.998706e-01	0.000	0	0
Metabolism of cofactors	R-HSA-8978934	9.998706e-01	0.000	0	0
Retinoid metabolism and transport	R-HSA-975634	9.998706e-01	0.000	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	9.998771e-01	0.000	0	0
Glucuronidation	R-HSA-156588	9.998771e-01	0.000	0	0
Purine catabolism	R-HSA-74259	9.998868e-01	0.000	0	0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	R-HSA-163841	9.998887e-01	0.000	0	0
Chondroitin sulfate/dermatan sulfate metabolism	R-HSA-1793185	9.998937e-01	0.000	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.998987e-01	0.000	0	0
Infection with Mycobacterium tuberculosis	R-HSA-9635486	9.999046e-01	0.000	0	0
Class B/2 (Secretin family receptors)	R-HSA-373080	9.999329e-01	0.000	0	0
G alpha (i) signalling events	R-HSA-418594	9.999385e-01	0.000	0	0
Sialic acid metabolism	R-HSA-4085001	9.999406e-01	0.000	0	0
Heparan sulfate/heparin (HS-GAG) metabolism	R-HSA-1638091	9.999406e-01	0.000	0	0
Metabolism of polyamines	R-HSA-351202	9.999487e-01	0.000	0	0
Cholesterol biosynthesis	R-HSA-191273	9.999495e-01	0.000	0	0
Role of phospholipids in phagocytosis	R-HSA-2029485	9.999539e-01	0.000	0	0
Collagen degradation	R-HSA-1442490	9.999556e-01	0.000	0	0
Collagen formation	R-HSA-1474290	9.999645e-01	0.000	0	0
Metabolism of fat-soluble vitamins	R-HSA-6806667	9.999663e-01	0.000	0	0
Complex I biogenesis	R-HSA-6799198	9.999668e-01	0.000	0	0
CD22 mediated BCR regulation	R-HSA-5690714	9.999713e-01	0.000	0	0
Mitochondrial translation elongation	R-HSA-5389840	9.999758e-01	0.000	0	0
Bile acid and bile salt metabolism	R-HSA-194068	9.999781e-01	0.000	0	0
Mitochondrial translation initiation	R-HSA-5368286	9.999813e-01	0.000	0	0
Metabolism of steroid hormones	R-HSA-196071	9.999815e-01	0.000	0	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.999836e-01	0.000	0	0
O-linked glycosylation of mucins	R-HSA-913709	9.999840e-01	0.000	0	0
Fatty acyl-CoA biosynthesis	R-HSA-75105	9.999880e-01	0.000	0	0
Metal ion assimilation from the host	R-HSA-9638482	9.999897e-01	0.000	0	0
Metabolism of porphyrins	R-HSA-189445	9.999897e-01	0.000	0	0
Mitochondrial translation	R-HSA-5368287	9.999901e-01	0.000	0	0
Keratinization	R-HSA-6805567	9.999908e-01	0.000	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	9.999923e-01	0.000	0	0
GPCR downstream signalling	R-HSA-388396	9.999933e-01	0.000	0	0
Citric acid cycle (TCA cycle)	R-HSA-71403	9.999942e-01	0.000	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.999952e-01	0.000	0	0
Metabolism of nucleotides	R-HSA-15869	9.999959e-01	0.000	0	0
Mitochondrial translation termination	R-HSA-5419276	9.999960e-01	0.000	0	0
Mitochondrial Fatty Acid Beta-Oxidation	R-HSA-77289	9.999962e-01	0.000	0	0
Infectious disease	R-HSA-5663205	9.999969e-01	0.000	0	0
Innate Immune System	R-HSA-168249	9.999974e-01	0.000	0	0
Sulfur amino acid metabolism	R-HSA-1614635	9.999990e-01	0.000	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	9.999991e-01	0.000	0	0
Pyruvate metabolism	R-HSA-70268	9.999991e-01	0.000	0	0
SLC-mediated transmembrane transport	R-HSA-425407	9.999992e-01	0.000	0	0
Visual phototransduction	R-HSA-2187338	9.999994e-01	0.000	0	0
Disease	R-HSA-1643685	9.999994e-01	0.000	0	0
Transport of small molecules	R-HSA-382551	9.999995e-01	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	9.999996e-01	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	9.999998e-01	0.000	0	0
Potassium Channels	R-HSA-1296071	9.999998e-01	0.000	0	0
Metabolism of proteins	R-HSA-392499	9.999999e-01	0.000	0	0
Signaling by GPCR	R-HSA-372790	9.999999e-01	0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	9.999999e-01	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	9.999999e-01	0.000	0	0
Drug ADME	R-HSA-9748784	9.999999e-01	0.000	0	0
Post-translational modification: synthesis of GPI-anchored proteins	R-HSA-163125	1.000000e+00	0.000	0	0
Regulation of Complement cascade	R-HSA-977606	1.000000e+00	0.000	0	0
Antimicrobial peptides	R-HSA-6803157	1.000000e+00	0.000	0	0
Synthesis of substrates in N-glycan biosythesis	R-HSA-446219	1.000000e+00	0.000	0	0
Initial triggering of complement	R-HSA-166663	1.000000e+00	0.000	0	0
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	1.000000e+00	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	1.000000e+00	0.000	0	0
O-linked glycosylation	R-HSA-5173105	1.000000e+00	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	1.000000e+00	0.000	0	0
Sensory perception of sweet, bitter, and umami (glutamate) taste	R-HSA-9717207	1.000000e+00	0.000	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	1.000000e+00	0.000	0	0
Glycosaminoglycan metabolism	R-HSA-1630316	1.000000e+00	0.000	0	0
Metabolism of steroids	R-HSA-8957322	1.000000e+00	0.000	0	0
Respiratory electron transport	R-HSA-611105	1.000000e+00	0.000	0	0
Complement cascade	R-HSA-166658	1.000000e+00	0.000	0	0
Diseases of glycosylation	R-HSA-3781865	1.000000e+00	0.000	0	0
Sensory perception of taste	R-HSA-9717189	1.000000e+00	0.000	0	0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	R-HSA-446193	1.000000e+00	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	1.000000e+00	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	1.000000e+00	0.000	0	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	0.000	0	0
Infection with Enterobacteria	R-HSA-9640148	1.000000e+00	0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	0.000	0	0
Phase II - Conjugation of compounds	R-HSA-156580	1.000000e+00	0.000	0	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	1.000000e+00	0.000	0	0
Expression and translocation of olfactory receptors	R-HSA-9752946	1.000000e+00	-0.000	0	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	-0.000	0	0
Olfactory Signaling Pathway	R-HSA-381753	1.000000e+00	-0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	-0.000	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	-0.000	0	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	-0.000	0	0
Phosphorylation of Emi1	R-HSA-176417	1.000000e+00	0.000	1	1
Mitotic Metaphase/Anaphase Transition	R-HSA-68881	1.000000e+00	0.000	1	1

Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download

name	reactome_id	p	-log10p	ref_path	ref_path_lowest
Cell Cycle	R-HSA-1640170	1.110223e-16	15.955	1	0
M Phase	R-HSA-68886	1.953993e-14	13.709	1	0
Cell Cycle, Mitotic	R-HSA-69278	5.728751e-14	13.242	1	0
Mitotic Prometaphase	R-HSA-68877	9.936496e-14	13.003	1	1
Separation of Sister Chromatids	R-HSA-2467813	1.667000e-12	11.778	1	1
Mitotic Anaphase	R-HSA-68882	3.282263e-12	11.484	1	0
Mitotic Metaphase and Anaphase	R-HSA-2555396	3.918199e-12	11.407	1	0
Cell Cycle Checkpoints	R-HSA-69620	2.499201e-11	10.602	1	0
Metabolism of RNA	R-HSA-8953854	5.098122e-11	10.293	0	0
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	6.777789e-11	10.169	1	1
Apoptotic cleavage of cellular proteins	R-HSA-111465	1.991045e-10	9.701	0	0
Translocation of SLC2A4 (GLUT4) to the plasma membrane	R-HSA-1445148	2.860422e-10	9.544	0	0
Recycling pathway of L1	R-HSA-437239	3.430954e-10	9.465	0	0
Cellular responses to stress	R-HSA-2262752	5.358550e-10	9.271	0	0
Apoptosis	R-HSA-109581	7.695444e-10	9.114	0	0
Cellular responses to stimuli	R-HSA-8953897	1.040254e-09	8.983	0	0
Apoptotic execution phase	R-HSA-75153	1.124134e-09	8.949	0	0
Aggrephagy	R-HSA-9646399	1.846921e-09	8.734	0	0
G2/M Transition	R-HSA-69275	2.702255e-09	8.568	1	0
Processing of Capped Intron-Containing Pre-mRNA	R-HSA-72203	2.882438e-09	8.540	0	0
Mitotic G2-G2/M phases	R-HSA-453274	3.718332e-09	8.430	1	0
Formation of tubulin folding intermediates by CCT/TriC	R-HSA-389960	4.980286e-09	8.303	0	0
L1CAM interactions	R-HSA-373760	7.412088e-09	8.130	0	0
EML4 and NUDC in mitotic spindle formation	R-HSA-9648025	1.100101e-08	7.959	1	1
Recruitment of NuMA to mitotic centrosomes	R-HSA-380320	1.935859e-08	7.713	1	1
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding	R-HSA-389958	2.180898e-08	7.661	0	0
Cell-Cell communication	R-HSA-1500931	2.329730e-08	7.633	0	0
Antiviral mechanism by IFN-stimulated genes	R-HSA-1169410	2.972895e-08	7.527	0	0
Regulation of CDH1 Function	R-HSA-9764561	4.006368e-08	7.397	0	0
Programmed Cell Death	R-HSA-5357801	5.322405e-08	7.274	0	0
G2/M Checkpoints	R-HSA-69481	7.212808e-08	7.142	0	0
Regulation of TP53 Activity	R-HSA-5633007	7.749078e-08	7.111	0	0
Prefoldin mediated transfer of substrate to CCT/TriC	R-HSA-389957	1.067426e-07	6.972	0	0
Diseases of signal transduction by growth factor receptors and second messengers	R-HSA-5663202	1.152896e-07	6.938	0	0
The role of GTSE1 in G2/M progression after G2 checkpoint	R-HSA-8852276	1.577927e-07	6.802	1	1
Transcriptional Regulation by TP53	R-HSA-3700989	2.359295e-07	6.627	0	0
Cellular response to heat stress	R-HSA-3371556	4.449739e-07	6.352	0	0
Cilium Assembly	R-HSA-5617833	4.500762e-07	6.347	1	0
mRNA Splicing	R-HSA-72172	5.886523e-07	6.230	0	0
Cell junction organization	R-HSA-446728	6.239577e-07	6.205	0	0
Selective autophagy	R-HSA-9663891	6.314465e-07	6.200	0	0
Axon guidance	R-HSA-422475	6.895089e-07	6.161	0	0
mRNA Splicing - Major Pathway	R-HSA-72163	7.570860e-07	6.121	0	0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	R-HSA-190840	7.683117e-07	6.114	0	0
Regulation of TP53 Degradation	R-HSA-6804757	9.409816e-07	6.026	0	0
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	9.407467e-07	6.027	1	1
Nuclear Envelope (NE) Reassembly	R-HSA-2995410	9.384038e-07	6.028	0	0
Nervous system development	R-HSA-9675108	1.131349e-06	5.946	0	0
Kinesins	R-HSA-983189	1.199612e-06	5.921	0	0
Transport of connexons to the plasma membrane	R-HSA-190872	1.247071e-06	5.904	0	0
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	2.119419e-06	5.674	1	1
Regulation of TP53 Expression and Degradation	R-HSA-6806003	2.382238e-06	5.623	0	0
PKR-mediated signaling	R-HSA-9833482	2.881982e-06	5.540	0	0
Post-chaperonin tubulin folding pathway	R-HSA-389977	3.058396e-06	5.515	0	0
Regulation of CDH1 Expression and Function	R-HSA-9764265	3.240472e-06	5.489	0	0
Regulation of Expression and Function of Type I Classical Cadherins	R-HSA-9764274	3.240472e-06	5.489	0	0
Gap junction trafficking	R-HSA-190828	3.353957e-06	5.474	0	0
Gap junction trafficking and regulation	R-HSA-157858	3.399777e-06	5.469	0	0
SARS-CoV-1-host interactions	R-HSA-9692914	3.638956e-06	5.439	0	0
Signaling by ERBB2	R-HSA-1227986	4.057390e-06	5.392	0	0
Membrane Trafficking	R-HSA-199991	4.284120e-06	5.368	0	0
Interferon Signaling	R-HSA-913531	4.442280e-06	5.352	0	0
Developmental Lineage of Mammary Gland Myoepithelial Cells	R-HSA-9927432	5.585728e-06	5.253	0	0
Assembly and cell surface presentation of NMDA receptors	R-HSA-9609736	5.587308e-06	5.253	0	0
Chaperone Mediated Autophagy	R-HSA-9613829	7.011561e-06	5.154	0	0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand	R-HSA-3371497	7.196100e-06	5.143	0	0
Downregulation of ERBB2 signaling	R-HSA-8863795	7.758225e-06	5.110	0	0
Regulation of TP53 Activity through Phosphorylation	R-HSA-6804756	1.075732e-05	4.968	0	0
Activation of AMPK downstream of NMDARs	R-HSA-9619483	1.749167e-05	4.757	0	0
Signal Transduction	R-HSA-162582	1.747273e-05	4.758	1	0
Ribosomal scanning and start codon recognition	R-HSA-72702	1.770257e-05	4.752	0	0
Regulation of localization of FOXO transcription factors	R-HSA-9614399	1.964286e-05	4.707	0	0
Mitotic Spindle Checkpoint	R-HSA-69618	2.139396e-05	4.670	1	0
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	2.444677e-05	4.612	1	1
Loss of Nlp from mitotic centrosomes	R-HSA-380259	2.444677e-05	4.612	1	1
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	R-HSA-72662	2.708443e-05	4.567	0	0
Adherens junctions interactions	R-HSA-418990	2.772368e-05	4.557	0	0
Signaling by ALK fusions and activated point mutants	R-HSA-9725370	2.840675e-05	4.547	0	0
Signaling by ALK in cancer	R-HSA-9700206	2.840675e-05	4.547	0	0
DNA Double-Strand Break Repair	R-HSA-5693532	3.100160e-05	4.509	0	0
MITF-M-regulated melanocyte development	R-HSA-9730414	3.376366e-05	4.472	1	0
Translation initiation complex formation	R-HSA-72649	3.668060e-05	4.436	0	0
Activation of BAD and translocation to mitochondria	R-HSA-111447	3.714679e-05	4.430	0	0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways	R-HSA-9755779	3.714679e-05	4.430	0	0
Degradation of CDH1	R-HSA-9766229	3.984031e-05	4.400	0	0
Cell-cell junction organization	R-HSA-421270	4.363108e-05	4.360	0	0
AURKA Activation by TPX2	R-HSA-8854518	4.381405e-05	4.358	1	1
Regulation of Homotypic Cell-Cell Adhesion	R-HSA-9759476	4.498424e-05	4.347	0	0
Major pathway of rRNA processing in the nucleolus and cytosol	R-HSA-6791226	5.235985e-05	4.281	0	0
HSF1-dependent transactivation	R-HSA-3371571	6.134829e-05	4.212	0	0
G2/M DNA damage checkpoint	R-HSA-69473	6.554180e-05	4.183	0	0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	R-HSA-141444	6.668476e-05	4.176	1	1
Amplification of signal from the kinetochores	R-HSA-141424	6.668476e-05	4.176	1	0
Sealing of the nuclear envelope (NE) by ESCRT-III	R-HSA-9668328	7.485940e-05	4.126	0	0
Deactivation of the beta-catenin transactivating complex	R-HSA-3769402	7.431837e-05	4.129	0	0
Josephin domain DUBs	R-HSA-5689877	7.599284e-05	4.119	0	0
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	8.933321e-05	4.049	0	0
SARS-CoV-1 Infection	R-HSA-9678108	8.933321e-05	4.049	0	0
Post NMDA receptor activation events	R-HSA-438064	9.130397e-05	4.040	0	0
Autophagy	R-HSA-9612973	9.450952e-05	4.025	0	0
Regulation of PTEN localization	R-HSA-8948747	9.682214e-05	4.014	0	0
Signaling by BRAF and RAF1 fusions	R-HSA-6802952	1.046335e-04	3.980	0	0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	R-HSA-8950505	1.046335e-04	3.980	0	0
PTEN Regulation	R-HSA-6807070	1.215899e-04	3.915	0	0
Regulation of mRNA stability by proteins that bind AU-rich elements	R-HSA-450531	1.273247e-04	3.895	0	0
Cap-dependent Translation Initiation	R-HSA-72737	1.281296e-04	3.892	0	0
Eukaryotic Translation Initiation	R-HSA-72613	1.281296e-04	3.892	0	0
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	1.503043e-04	3.823	1	1
rRNA processing in the nucleus and cytosol	R-HSA-8868773	1.635151e-04	3.786	0	0
Macroautophagy	R-HSA-1632852	1.526781e-04	3.816	0	0
Regulation of HSF1-mediated heat shock response	R-HSA-3371453	1.744061e-04	3.758	0	0
S Phase	R-HSA-69242	1.745524e-04	3.758	0	0
Organelle biogenesis and maintenance	R-HSA-1852241	1.817162e-04	3.741	1	0
GTP hydrolysis and joining of the 60S ribosomal subunit	R-HSA-72706	1.878337e-04	3.726	0	0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	R-HSA-8866652	2.116901e-04	3.674	0	0
Formation of the ternary complex, and subsequently, the 43S complex	R-HSA-72695	2.112975e-04	3.675	0	0
Centrosome maturation	R-HSA-380287	2.074895e-04	3.683	1	0
Protein folding	R-HSA-391251	2.206674e-04	3.656	0	0
Chaperonin-mediated protein folding	R-HSA-390466	2.298284e-04	3.639	0	0
VEGFA-VEGFR2 Pathway	R-HSA-4420097	2.554529e-04	3.593	0	0
Intra-Golgi and retrograde Golgi-to-ER traffic	R-HSA-6811442	2.582229e-04	3.588	0	0
SARS-CoV-2-host interactions	R-HSA-9705683	2.597192e-04	3.585	0	0
MHC class II antigen presentation	R-HSA-2132295	2.995707e-04	3.524	0	0
Downregulation of ERBB2:ERBB3 signaling	R-HSA-1358803	3.061653e-04	3.514	0	0
Transcriptional Regulation by E2F6	R-HSA-8953750	3.936430e-04	3.405	0	0
COPI-independent Golgi-to-ER retrograde traffic	R-HSA-6811436	3.939499e-04	3.405	0	0
HDR through Homologous Recombination (HRR)	R-HSA-5685942	3.992772e-04	3.399	0	0
Gap junction assembly	R-HSA-190861	4.294759e-04	3.367	0	0
COPI-dependent Golgi-to-ER retrograde traffic	R-HSA-6811434	4.322016e-04	3.364	0	0
HIV Life Cycle	R-HSA-162587	4.416723e-04	3.355	0	0
APC-Cdc20 mediated degradation of Nek2A	R-HSA-179409	4.523838e-04	3.344	0	0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	R-HSA-75035	4.549381e-04	3.342	0	0
Activation of BH3-only proteins	R-HSA-114452	4.563559e-04	3.341	0	0
Folding of actin by CCT/TriC	R-HSA-390450	4.667241e-04	3.331	0	0
Attenuation phase	R-HSA-3371568	4.847988e-04	3.314	0	0
Protein ubiquitination	R-HSA-8852135	5.293969e-04	3.276	0	0
EPH-Ephrin signaling	R-HSA-2682334	5.238442e-04	3.281	0	0
Nuclear Envelope Breakdown	R-HSA-2980766	5.555686e-04	3.255	1	0
Signaling by Hippo	R-HSA-2028269	5.576745e-04	3.254	0	0
Transport of Mature Transcript to Cytoplasm	R-HSA-72202	5.853719e-04	3.233	0	0
Interleukin-12 signaling	R-HSA-9020591	6.120659e-04	3.213	0	0
Formation of the polybromo-BAF (pBAF) complex	R-HSA-9933939	6.575993e-04	3.182	0	0
HSF1 activation	R-HSA-3371511	6.632175e-04	3.178	0	0
Cytokine Signaling in Immune system	R-HSA-1280215	6.734335e-04	3.172	0	0
Cohesin Loading onto Chromatin	R-HSA-2470946	6.757016e-04	3.170	0	0
InlA-mediated entry of Listeria monocytogenes into host cells	R-HSA-8876493	7.183067e-04	3.144	0	0
Transcriptional and post-translational regulation of MITF-M expression and activity	R-HSA-9856649	7.351080e-04	3.134	0	0
Regulation of PTEN stability and activity	R-HSA-8948751	7.719914e-04	3.112	0	0
Homology Directed Repair	R-HSA-5693538	7.819453e-04	3.107	0	0
Downregulation of TGF-beta receptor signaling	R-HSA-2173788	7.919371e-04	3.101	0	0
HIV Infection	R-HSA-162906	7.906303e-04	3.102	0	0
TP53 Regulates Transcription of DNA Repair Genes	R-HSA-6796648	8.113726e-04	3.091	0	0
Drug resistance in ERBB2 KD mutants	R-HSA-9665230	8.522784e-04	3.069	0	0
Drug-mediated inhibition of ERBB2 signaling	R-HSA-9652282	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to osimertinib	R-HSA-9665247	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to lapatinib	R-HSA-9665251	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to tesevatinib	R-HSA-9665245	8.522784e-04	3.069	0	0
Drug resistance in ERBB2 TMD/JMD mutants	R-HSA-9665737	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to sapitinib	R-HSA-9665244	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to trastuzumab	R-HSA-9665233	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to neratinib	R-HSA-9665246	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to AEE788	R-HSA-9665250	8.522784e-04	3.069	0	0
Resistance of ERBB2 KD mutants to afatinib	R-HSA-9665249	8.522784e-04	3.069	0	0
FLT3 signaling by CBL mutants	R-HSA-9706377	8.780002e-04	3.057	0	0
MITF-M-dependent gene expression	R-HSA-9856651	8.774749e-04	3.057	1	0
Intraflagellar transport	R-HSA-5620924	9.036549e-04	3.044	0	0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	R-HSA-5693567	8.553469e-04	3.068	0	0
Signaling by VEGF	R-HSA-194138	8.818168e-04	3.055	0	0
Activation of NMDA receptors and postsynaptic events	R-HSA-442755	9.048385e-04	3.043	0	0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	R-HSA-2173791	9.274419e-04	3.033	0	0
Cell-extracellular matrix interactions	R-HSA-446353	9.274419e-04	3.033	0	0
p75NTR signals via NF-kB	R-HSA-193639	9.274419e-04	3.033	0	0
L13a-mediated translational silencing of Ceruloplasmin expression	R-HSA-156827	9.336455e-04	3.030	0	0
Switching of origins to a post-replicative state	R-HSA-69052	9.793284e-04	3.009	0	0
COPI-mediated anterograde transport	R-HSA-6807878	9.798216e-04	3.009	0	0
TGF-beta receptor signaling activates SMADs	R-HSA-2173789	1.050140e-03	2.979	0	0
ATF6 (ATF6-alpha) activates chaperone genes	R-HSA-381183	1.066783e-03	2.972	0	0
NF-kB is activated and signals survival	R-HSA-209560	1.066783e-03	2.972	0	0
Mitotic Telophase/Cytokinesis	R-HSA-68884	1.066783e-03	2.972	1	1
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation	R-HSA-9828211	1.098532e-03	2.959	0	0
Formation of annular gap junctions	R-HSA-196025	1.098532e-03	2.959	0	0
DNA Damage Recognition in GG-NER	R-HSA-5696394	1.119566e-03	2.951	0	0
Striated Muscle Contraction	R-HSA-390522	1.119566e-03	2.951	0	0
Transport of Mature mRNA Derived from an Intronless Transcript	R-HSA-159231	1.208860e-03	2.918	0	0
Processing of DNA double-strand break ends	R-HSA-5693607	1.214074e-03	2.916	0	0
Apoptotic cleavage of cell adhesion proteins	R-HSA-351906	1.098532e-03	2.959	0	0
Signaling by Receptor Tyrosine Kinases	R-HSA-9006934	1.108158e-03	2.955	0	0
ISG15 antiviral mechanism	R-HSA-1169408	1.289886e-03	2.889	0	0
Gene expression (Transcription)	R-HSA-74160	1.314933e-03	2.881	0	0
Recognition of DNA damage by PCNA-containing replication complex	R-HSA-110314	1.317748e-03	2.880	0	0
Nephrin family interactions	R-HSA-373753	1.346672e-03	2.871	0	0
rRNA modification in the nucleus and cytosol	R-HSA-6790901	1.421694e-03	2.847	0	0
Transport of Mature mRNAs Derived from Intronless Transcripts	R-HSA-159234	1.458296e-03	2.836	0	0
Interactions of Rev with host cellular proteins	R-HSA-177243	1.458296e-03	2.836	0	0
Regulation of MITF-M-dependent genes involved in pigmentation	R-HSA-9824585	1.495670e-03	2.825	0	0
DNA Repair	R-HSA-73894	1.498324e-03	2.824	0	0
p75NTR recruits signalling complexes	R-HSA-209543	1.535918e-03	2.814	0	0
Late Phase of HIV Life Cycle	R-HSA-162599	1.574008e-03	2.803	0	0
SARS-CoV Infections	R-HSA-9679506	1.613450e-03	2.792	0	0
ATP-dependent chromatin remodelers	R-HSA-9932444	1.671314e-03	2.777	0	0
SWI/SNF chromatin remodelers	R-HSA-9932451	1.671314e-03	2.777	0	0
Gap junction degradation	R-HSA-190873	1.699524e-03	2.770	0	0
Caspase-mediated cleavage of cytoskeletal proteins	R-HSA-264870	1.699524e-03	2.770	0	0
Viral Infection Pathways	R-HSA-9824446	1.714607e-03	2.766	0	0
Epigenetic regulation of gene expression	R-HSA-212165	1.738694e-03	2.760	0	0
Autodegradation of Cdh1 by Cdh1:APC/C	R-HSA-174084	1.771679e-03	2.752	0	0
APC/C-mediated degradation of cell cycle proteins	R-HSA-174143	1.789664e-03	2.747	1	0
Regulation of mitotic cell cycle	R-HSA-453276	1.789664e-03	2.747	1	0
Oncogenic MAPK signaling	R-HSA-6802957	2.007356e-03	2.697	0	0
Golgi-to-ER retrograde transport	R-HSA-8856688	1.948158e-03	2.710	0	0
Cellular Senescence	R-HSA-2559583	1.953138e-03	2.709	0	0
KEAP1-NFE2L2 pathway	R-HSA-9755511	1.848900e-03	2.733	0	0
Cargo trafficking to the periciliary membrane	R-HSA-5620920	1.789664e-03	2.747	0	0
Cyclin A:Cdk2-associated events at S phase entry	R-HSA-69656	2.043946e-03	2.690	0	0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	R-HSA-174178	2.049568e-03	2.688	1	1
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	R-HSA-179419	2.049568e-03	2.688	0	0
Signaling by RAF1 mutants	R-HSA-9656223	2.086026e-03	2.681	0	0
Intracellular signaling by second messengers	R-HSA-9006925	2.098239e-03	2.678	0	0
Formation of the non-canonical BAF (ncBAF) complex	R-HSA-9933947	2.151941e-03	2.667	0	0
ATF6 (ATF6-alpha) activates chaperones	R-HSA-381033	2.151941e-03	2.667	0	0
Chromatin organization	R-HSA-4839726	2.235398e-03	2.651	0	0
Regulation of PTEN gene transcription	R-HSA-8943724	2.287657e-03	2.641	0	0
Negative Regulation of CDH1 Gene Transcription	R-HSA-9764725	2.287657e-03	2.641	0	0
Transport of Mature mRNA derived from an Intron-Containing Transcript	R-HSA-159236	2.327921e-03	2.633	0	0
Vesicle-mediated transport	R-HSA-5653656	2.350073e-03	2.629	0	0
CDK-mediated phosphorylation and removal of Cdc6	R-HSA-69017	2.384400e-03	2.623	0	0
Nonhomologous End-Joining (NHEJ)	R-HSA-5693571	2.451280e-03	2.611	0	0
Establishment of Sister Chromatid Cohesion	R-HSA-2468052	2.522119e-03	2.598	0	0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	R-HSA-428359	2.522119e-03	2.598	0	0
TNFR1-induced NF-kappa-B signaling pathway	R-HSA-5357956	2.608308e-03	2.584	0	0
RNA Polymerase II Pre-transcription Events	R-HSA-674695	2.644223e-03	2.578	0	0
APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176409	2.763309e-03	2.559	0	0
Formation of the canonical BAF (cBAF) complex	R-HSA-9933937	2.943235e-03	2.531	0	0
Ephrin signaling	R-HSA-3928664	3.003090e-03	2.522	0	0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	R-HSA-176814	3.190560e-03	2.496	1	0
Regulation of APC/C activators between G1/S and early anaphase	R-HSA-176408	3.021100e-03	2.520	1	0
Rev-mediated nuclear export of HIV RNA	R-HSA-165054	2.914044e-03	2.536	0	0
Host Interactions of HIV factors	R-HSA-162909	2.908861e-03	2.536	0	0
Intrinsic Pathway for Apoptosis	R-HSA-109606	3.190560e-03	2.496	0	0
Regulation of TP53 Activity through Acetylation	R-HSA-6804758	2.819382e-03	2.550	0	0
Influenza Infection	R-HSA-168255	3.232629e-03	2.490	0	0
Interleukin-12 family signaling	R-HSA-447115	2.857489e-03	2.544	0	0
Hedgehog 'off' state	R-HSA-5610787	3.281571e-03	2.484	0	0
Deubiquitination	R-HSA-5688426	3.307942e-03	2.480	0	0
Stabilization of p53	R-HSA-69541	3.463174e-03	2.461	0	0
NS1 Mediated Effects on Host Pathways	R-HSA-168276	3.463174e-03	2.461	0	0
Constitutive Signaling by AKT1 E17K in Cancer	R-HSA-5674400	3.584229e-03	2.446	0	0
Regulation of CDH1 Gene Transcription	R-HSA-9764560	3.661470e-03	2.436	0	0
Cyclin E associated events during G1/S transition	R-HSA-69202	3.661470e-03	2.436	0	0
Chromatin modifying enzymes	R-HSA-3247509	3.848898e-03	2.415	0	0
APC/C:Cdc20 mediated degradation of Cyclin B	R-HSA-174048	3.865516e-03	2.413	0	0
Impaired BRCA2 binding to PALB2	R-HSA-9709603	3.865516e-03	2.413	0	0
Late endosomal microautophagy	R-HSA-9615710	3.925221e-03	2.406	0	0
Impaired BRCA2 binding to RAD51	R-HSA-9709570	3.925221e-03	2.406	0	0
TICAM1, RIP1-mediated IKK complex recruitment	R-HSA-168927	3.939972e-03	2.405	0	0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	R-HSA-9735871	3.939972e-03	2.405	0	0
Unfolded Protein Response (UPR)	R-HSA-381119	3.972781e-03	2.401	0	0
SARS-CoV-1 modulates host translation machinery	R-HSA-9735869	4.078190e-03	2.390	0	0
Diseases of DNA Double-Strand Break Repair	R-HSA-9675136	4.078190e-03	2.390	0	0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function	R-HSA-9701190	4.078190e-03	2.390	0	0
Positive epigenetic regulation of rRNA expression	R-HSA-5250913	4.143102e-03	2.383	0	0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7	R-HSA-9824878	5.019238e-03	2.299	0	0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)	R-HSA-9934037	4.907624e-03	2.309	0	0
Defective homologous recombination repair (HRR) due to PALB2 loss of function	R-HSA-9701193	4.907624e-03	2.309	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function	R-HSA-9704646	4.907624e-03	2.309	0	0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function	R-HSA-9701192	4.907624e-03	2.309	0	0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function	R-HSA-9704331	4.907624e-03	2.309	0	0
Signaling downstream of RAS mutants	R-HSA-9649948	4.666318e-03	2.331	0	0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A	R-HSA-174184	4.456857e-03	2.351	0	0
Developmental Lineages of the Mammary Gland	R-HSA-9924644	4.675610e-03	2.330	0	0
Response of EIF2AK4 (GCN2) to amino acid deficiency	R-HSA-9633012	4.906671e-03	2.309	0	0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	R-HSA-5693565	4.808436e-03	2.318	0	0
TICAM1-dependent activation of IRF3/IRF7	R-HSA-9013973	5.019238e-03	2.299	0	0
Signaling by moderate kinase activity BRAF mutants	R-HSA-6802946	4.666318e-03	2.331	0	0
Paradoxical activation of RAF signaling by kinase inactive BRAF	R-HSA-6802955	4.666318e-03	2.331	0	0
Golgi Associated Vesicle Biogenesis	R-HSA-432722	5.124446e-03	2.290	0	0
Regulation of NF-kappa B signaling	R-HSA-9758274	5.173691e-03	2.286	0	0
trans-Golgi Network Vesicle Budding	R-HSA-199992	4.675610e-03	2.330	0	0
Signaling by RAS mutants	R-HSA-6802949	4.666318e-03	2.331	0	0
Orc1 removal from chromatin	R-HSA-68949	4.456857e-03	2.351	0	0
Signaling by TGF-beta Receptor Complex	R-HSA-170834	4.937240e-03	2.307	0	0
Smooth Muscle Contraction	R-HSA-445355	5.124446e-03	2.290	0	0
Diseases of DNA repair	R-HSA-9675135	4.666318e-03	2.331	0	0
SARS-CoV-2 Infection	R-HSA-9694516	4.790897e-03	2.320	0	0
Carboxyterminal post-translational modifications of tubulin	R-HSA-8955332	5.406205e-03	2.267	0	0
APC/C:Cdc20 mediated degradation of Securin	R-HSA-174154	5.406205e-03	2.267	0	0
Eukaryotic Translation Elongation	R-HSA-156842	5.474007e-03	2.262	0	0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)	R-HSA-9845323	5.476211e-03	2.262	0	0
rRNA processing	R-HSA-72312	5.577843e-03	2.254	0	0
DNA Double Strand Break Response	R-HSA-5693606	5.733521e-03	2.242	0	0
Signaling by NOTCH4	R-HSA-9013694	5.908935e-03	2.228	0	0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence	R-HSA-9825895	6.029219e-03	2.220	0	0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	R-HSA-8849469	6.029219e-03	2.220	0	0
Modulation by Mtb of host immune system	R-HSA-9637628	6.029219e-03	2.220	0	0
Signaling by Ligand-Responsive EGFR Variants in Cancer	R-HSA-5637815	6.152256e-03	2.211	0	0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	R-HSA-1236382	6.152256e-03	2.211	0	0
G1/S Transition	R-HSA-69206	6.614201e-03	2.180	0	0
Ribosome-associated quality control	R-HSA-9948299	6.711190e-03	2.173	0	0
Diseases of mitotic cell cycle	R-HSA-9675126	6.828518e-03	2.166	0	0
p53-Dependent G1/S DNA damage checkpoint	R-HSA-69580	7.166448e-03	2.145	0	0
p53-Dependent G1 DNA Damage Response	R-HSA-69563	7.166448e-03	2.145	0	0
UCH proteinases	R-HSA-5689603	7.394234e-03	2.131	0	0
Mitotic Prophase	R-HSA-68875	7.417193e-03	2.130	1	0
Listeria monocytogenes entry into host cells	R-HSA-8876384	7.622861e-03	2.118	0	0
Homologous DNA Pairing and Strand Exchange	R-HSA-5693579	7.916007e-03	2.101	0	0
Semaphorin interactions	R-HSA-373755	7.939647e-03	2.100	0	0
Regulation of endogenous retroelements	R-HSA-9842860	7.992566e-03	2.097	0	0
EPHA-mediated growth cone collapse	R-HSA-3928663	8.041014e-03	2.095	0	0
Transport of the SLBP independent Mature mRNA	R-HSA-159227	8.097254e-03	2.092	0	0
Regulation of necroptotic cell death	R-HSA-5675482	8.097254e-03	2.092	0	0
Resolution of D-loop Structures through Holliday Junction Intermediates	R-HSA-5693568	8.097254e-03	2.092	0	0
HDR through Single Strand Annealing (SSA)	R-HSA-5685938	8.097254e-03	2.092	0	0
Activation of ATR in response to replication stress	R-HSA-176187	8.097254e-03	2.092	0	0
Cytosolic sensors of pathogen-associated DNA	R-HSA-1834949	8.139559e-03	2.089	0	0
PIP3 activates AKT signaling	R-HSA-1257604	8.444989e-03	2.073	0	0
AKT phosphorylates targets in the nucleus	R-HSA-198693	8.576100e-03	2.067	0	0
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	R-HSA-2559584	8.976681e-03	2.047	0	0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition	R-HSA-9926550	1.062300e-02	1.974	0	0
Transport of the SLBP Dependant Mature mRNA	R-HSA-159230	9.539893e-03	2.020	0	0
Association of TriC/CCT with target proteins during biosynthesis	R-HSA-390471	9.539893e-03	2.020	0	0
GSK3B-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929356	9.213985e-03	2.036	0	0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	R-HSA-73779	1.067030e-02	1.972	0	0
E3 ubiquitin ligases ubiquitinate target proteins	R-HSA-8866654	1.062446e-02	1.974	0	0
mRNA 3'-end processing	R-HSA-72187	1.062446e-02	1.974	0	0
EPHB-mediated forward signaling	R-HSA-3928662	8.746782e-03	2.058	0	0
Resolution of D-Loop Structures	R-HSA-5693537	9.539893e-03	2.020	0	0
Activation of NF-kappaB in B cells	R-HSA-1169091	9.352093e-03	2.029	0	0
MAPK6/MAPK4 signaling	R-HSA-5687128	9.150265e-03	2.039	0	0
DNA Replication Pre-Initiation	R-HSA-69002	8.550213e-03	2.068	0	0
TCR signaling	R-HSA-202403	9.330308e-03	2.030	0	0
RUNX1 regulates expression of components of tight junctions	R-HSA-8935964	9.895164e-03	2.005	0	0
Negative regulation of NOTCH4 signaling	R-HSA-9604323	1.067030e-02	1.972	0	0
Depolymerization of the Nuclear Lamina	R-HSA-4419969	1.062300e-02	1.974	0	0
Maturation of protein E	R-HSA-9683683	9.895164e-03	2.005	0	0
Maturation of protein E	R-HSA-9694493	9.895164e-03	2.005	0	0
Nuclear import of Rev protein	R-HSA-180746	1.117083e-02	1.952	0	0
Regulation of TNFR1 signaling	R-HSA-5357905	1.148159e-02	1.940	0	0
MAP3K8 (TPL2)-dependent MAPK1/3 activation	R-HSA-5684264	1.162404e-02	1.935	0	0
NRIF signals cell death from the nucleus	R-HSA-205043	1.162404e-02	1.935	0	0
p75 NTR receptor-mediated signalling	R-HSA-193704	1.174098e-02	1.930	0	0
TICAM1,TRAF6-dependent induction of TAK1 complex	R-HSA-9014325	1.178406e-02	1.929	0	0
Pexophagy	R-HSA-9664873	1.178406e-02	1.929	0	0
Assembly of the pre-replicative complex	R-HSA-68867	1.202983e-02	1.920	0	0
VEGFR2 mediated vascular permeability	R-HSA-5218920	1.229672e-02	1.910	0	0
SPOP-mediated proteasomal degradation of PD-L1(CD274)	R-HSA-9929491	1.229672e-02	1.910	0	0
Hh mutants are degraded by ERAD	R-HSA-5362768	1.229672e-02	1.910	0	0
SCF-beta-TrCP mediated degradation of Emi1	R-HSA-174113	1.300455e-02	1.886	0	0
Formation of WDR5-containing histone-modifying complexes	R-HSA-9772755	1.300455e-02	1.886	0	0
Regulation of Apoptosis	R-HSA-169911	1.300455e-02	1.886	0	0
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-5693616	1.300455e-02	1.886	0	0
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	1.307457e-02	1.884	0	0
IKK complex recruitment mediated by RIP1	R-HSA-937041	1.313118e-02	1.882	0	0
Regulation of signaling by CBL	R-HSA-912631	1.313118e-02	1.882	0	0
Mitotic G1 phase and G1/S transition	R-HSA-453279	1.315428e-02	1.881	0	0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)	R-HSA-5619107	1.350229e-02	1.870	0	0
Synthesis of DNA	R-HSA-69239	1.352008e-02	1.869	0	0
RNA Polymerase II HIV Promoter Escape	R-HSA-167162	1.410508e-02	1.851	0	0
HIV Transcription Initiation	R-HSA-167161	1.410508e-02	1.851	0	0
RNA Polymerase II Transcription Initiation	R-HSA-75953	1.410508e-02	1.851	0	0
Influenza Viral RNA Transcription and Replication	R-HSA-168273	1.436144e-02	1.843	0	0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	R-HSA-9954716	1.439788e-02	1.842	0	0
Nuclear events mediated by NFE2L2	R-HSA-9759194	1.467770e-02	1.833	0	0
Developmental Cell Lineages of the Integumentary System	R-HSA-9734779	1.468207e-02	1.833	0	0
Sema3A PAK dependent Axon repulsion	R-HSA-399954	1.477865e-02	1.830	0	0
Formation of the embryonic stem cell BAF (esBAF) complex	R-HSA-9933946	1.477865e-02	1.830	0	0
STAT3 nuclear events downstream of ALK signaling	R-HSA-9701898	1.477865e-02	1.830	0	0
AUF1 (hnRNP D0) binds and destabilizes mRNA	R-HSA-450408	1.505551e-02	1.822	0	0
HDACs deacetylate histones	R-HSA-3214815	1.525898e-02	1.816	0	0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins	R-HSA-9673766	1.539470e-02	1.813	0	0
Formation of a pool of free 40S subunits	R-HSA-72689	1.571183e-02	1.804	0	0
Alpha-protein kinase 1 signaling pathway	R-HSA-9645460	1.572257e-02	1.803	0	0
IP3 and IP4 transport between cytosol and nucleus	R-HSA-1855196	1.582286e-02	1.801	0	0
Regulation of activated PAK-2p34 by proteasome mediated degradation	R-HSA-211733	1.582286e-02	1.801	0	0
IP6 and IP7 transport between cytosol and nucleus	R-HSA-1855229	1.582286e-02	1.801	0	0
Sema4D induced cell migration and growth-cone collapse	R-HSA-416572	1.603821e-02	1.795	0	0
RNA Polymerase I Transcription Initiation	R-HSA-73762	1.610719e-02	1.793	0	0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	R-HSA-5693554	1.624052e-02	1.789	0	0
Sema4D in semaphorin signaling	R-HSA-400685	1.624052e-02	1.789	0	0
HCMV Early Events	R-HSA-9609690	1.694728e-02	1.771	0	0
Cellular response to chemical stress	R-HSA-9711123	1.711878e-02	1.767	0	0
G1/S DNA Damage Checkpoints	R-HSA-69615	1.720737e-02	1.764	0	0
Vpr-mediated nuclear import of PICs	R-HSA-180910	1.733803e-02	1.761	0	0
Ovarian tumor domain proteases	R-HSA-5689896	1.733803e-02	1.761	0	0
Degradation of DVL	R-HSA-4641258	1.733803e-02	1.761	0	0
Signaling by high-kinase activity BRAF mutants	R-HSA-6802948	1.733803e-02	1.761	0	0
Formation of editosomes by ADAR proteins	R-HSA-77042	1.839242e-02	1.735	0	0
Defective Inhibition of DNA Recombination at Telomere	R-HSA-9670621	1.839242e-02	1.735	0	0
Alternative Lengthening of Telomeres (ALT)	R-HSA-9006821	1.839242e-02	1.735	0	0
Diseases of Telomere Maintenance	R-HSA-9673013	1.839242e-02	1.735	0	0
Defective Mismatch Repair Associated With MSH6	R-HSA-5632968	1.839242e-02	1.735	0	0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations	R-HSA-9670615	1.839242e-02	1.735	0	0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations	R-HSA-9670613	1.839242e-02	1.735	0	0
Recycling of eIF2:GDP	R-HSA-72731	2.061770e-02	1.686	0	0
Aberrant regulation of mitotic exit in cancer due to RB1 defects	R-HSA-9687136	1.848319e-02	1.733	0	0
RNA Polymerase III Transcription Initiation From Type 2 Promoter	R-HSA-76066	2.316663e-02	1.635	0	0
Signaling by EGFR in Cancer	R-HSA-1643713	1.919554e-02	1.717	0	0
Interaction between L1 and Ankyrins	R-HSA-445095	2.251522e-02	1.648	0	0
IPs transport between nucleus and cytosol	R-HSA-1855170	2.132075e-02	1.671	0	0
RNA Polymerase II Promoter Escape	R-HSA-73776	1.831476e-02	1.737	0	0
RNA Polymerase II Transcription Initiation And Promoter Clearance	R-HSA-76042	2.339226e-02	1.631	0	0
Nucleosome assembly	R-HSA-774815	2.339226e-02	1.631	0	0
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	2.339226e-02	1.631	0	0
Neutrophil degranulation	R-HSA-6798695	2.145770e-02	1.668	0	0
RIPK1-mediated regulated necrosis	R-HSA-5213460	1.986619e-02	1.702	0	0
Ub-specific processing proteases	R-HSA-5689880	1.780517e-02	1.749	0	0
Meiosis	R-HSA-1500620	1.817053e-02	1.741	0	0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	R-HSA-936964	2.277668e-02	1.643	0	0
Death Receptor Signaling	R-HSA-73887	2.239773e-02	1.650	0	0
Hh mutants abrogate ligand secretion	R-HSA-5387390	1.831476e-02	1.737	0	0
Defective CFTR causes cystic fibrosis	R-HSA-5678895	2.339226e-02	1.631	0	0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A	R-HSA-69601	2.339226e-02	1.631	0	0
p53-Independent G1/S DNA Damage Checkpoint	R-HSA-69613	2.339226e-02	1.631	0	0
Muscle contraction	R-HSA-397014	1.791625e-02	1.747	0	0
Cyclin A/B1/B2 associated events during G2/M transition	R-HSA-69273	2.132075e-02	1.671	1	1
snRNP Assembly	R-HSA-191859	2.365816e-02	1.626	0	0
Metabolism of non-coding RNA	R-HSA-194441	2.365816e-02	1.626	0	0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	R-HSA-9931269	2.368874e-02	1.625	0	0
Vpu mediated degradation of CD4	R-HSA-180534	2.453181e-02	1.610	0	0
Regulation of Glucokinase by Glucokinase Regulatory Protein	R-HSA-170822	2.453181e-02	1.610	0	0
Transcriptional regulation by RUNX1	R-HSA-8878171	2.454465e-02	1.610	0	0
SARS-CoV-2 targets PDZ proteins in cell-cell junction	R-HSA-9705677	2.468972e-02	1.607	0	0
TLR3-mediated TICAM1-dependent programmed cell death	R-HSA-9013957	2.468972e-02	1.607	0	0
AKT-mediated inactivation of FOXO1A	R-HSA-211163	2.468972e-02	1.607	0	0
Interactions of Vpr with host cellular proteins	R-HSA-176033	2.571389e-02	1.590	0	0
Regulation of RUNX3 expression and activity	R-HSA-8941858	2.571389e-02	1.590	0	0
Peptide chain elongation	R-HSA-156902	2.574036e-02	1.589	0	0
Constitutive Signaling by Overexpressed ERBB2	R-HSA-9634285	2.602749e-02	1.585	0	0
VLDLR internalisation and degradation	R-HSA-8866427	2.602749e-02	1.585	0	0
IRAK1 recruits IKK complex	R-HSA-937039	2.602749e-02	1.585	0	0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	R-HSA-975144	2.602749e-02	1.585	0	0
PINK1-PRKN Mediated Mitophagy	R-HSA-5205685	2.621990e-02	1.581	0	0
mTORC1-mediated signalling	R-HSA-166208	2.744196e-02	1.562	0	0
Notch-HLH transcription pathway	R-HSA-350054	2.744196e-02	1.562	0	0
RNA Polymerase III Transcription Initiation From Type 1 Promoter	R-HSA-76061	2.744196e-02	1.562	0	0
Type I hemidesmosome assembly	R-HSA-446107	2.790049e-02	1.554	0	0
Myoclonic epilepsy of Lafora	R-HSA-3785653	2.790049e-02	1.554	0	0
Downregulation of ERBB4 signaling	R-HSA-1253288	2.790049e-02	1.554	0	0
Dual Incision in GG-NER	R-HSA-5696400	2.807220e-02	1.552	0	0
Autodegradation of the E3 ubiquitin ligase COP1	R-HSA-349425	2.807220e-02	1.552	0	0
Ubiquitin-dependent degradation of Cyclin D	R-HSA-75815	2.807220e-02	1.552	0	0
Calnexin/calreticulin cycle	R-HSA-901042	2.807220e-02	1.552	0	0
RNA Polymerase II Transcription Termination	R-HSA-73856	2.895705e-02	1.538	0	0
FLT3 Signaling	R-HSA-9607240	2.905938e-02	1.537	0	0
PKMTs methylate histone lysines	R-HSA-3214841	2.905938e-02	1.537	0	0
Clathrin-mediated endocytosis	R-HSA-8856828	3.024966e-02	1.519	0	0
Global Genome Nucleotide Excision Repair (GG-NER)	R-HSA-5696399	3.160330e-02	1.500	0	0
Nuclear Pore Complex (NPC) Disassembly	R-HSA-3301854	3.195668e-02	1.495	0	0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	R-HSA-9860927	3.195668e-02	1.495	0	0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	R-HSA-8854050	3.195668e-02	1.495	0	0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling	R-HSA-9634638	3.222332e-02	1.492	0	0
Membrane binding and targetting of GAG proteins	R-HSA-174490	3.248812e-02	1.488	0	0
Signaling by NOTCH3	R-HSA-9012852	3.252038e-02	1.488	0	0
MAP2K and MAPK activation	R-HSA-5674135	3.270221e-02	1.485	0	0
Degradation of GLI1 by the proteasome	R-HSA-5610780	3.270221e-02	1.485	0	0
Degradation of GLI2 by the proteasome	R-HSA-5610783	3.270221e-02	1.485	0	0
GLI3 is processed to GLI3R by the proteasome	R-HSA-5610785	3.270221e-02	1.485	0	0
Signaling by ERBB2 ECD mutants	R-HSA-9665348	3.326490e-02	1.478	0	0
Regulation of TP53 Activity through Methylation	R-HSA-6804760	3.326490e-02	1.478	0	0
Downstream signaling events of B Cell Receptor (BCR)	R-HSA-1168372	3.402363e-02	1.468	0	0
Signaling by Hedgehog	R-HSA-5358351	3.409727e-02	1.467	0	0
Aberrant regulation of mitotic cell cycle due to RB1 defects	R-HSA-9687139	3.485837e-02	1.458	0	0
RNA Polymerase III Transcription Initiation	R-HSA-76046	3.485837e-02	1.458	0	0
Signaling by Non-Receptor Tyrosine Kinases	R-HSA-9006927	3.507169e-02	1.455	0	0
Signaling by PTK6	R-HSA-8848021	3.507169e-02	1.455	0	0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	R-HSA-975956	3.546569e-02	1.450	0	0
PCP/CE pathway	R-HSA-4086400	3.575417e-02	1.447	0	0
TNF signaling	R-HSA-75893	3.592843e-02	1.445	0	0
RNA Polymerase III Abortive And Retractive Initiation	R-HSA-749476	3.619890e-02	1.441	0	0
RNA Polymerase III Transcription	R-HSA-74158	3.619890e-02	1.441	0	0
Vif-mediated degradation of APOBEC3G	R-HSA-180585	3.619890e-02	1.441	0	0
Regulation of MITF-M dependent genes involved in invasion	R-HSA-9854909	3.640365e-02	1.439	0	0
Loss of Function of TGFBR1 in Cancer	R-HSA-3656534	3.640365e-02	1.439	0	0
Nectin/Necl trans heterodimerization	R-HSA-420597	3.640365e-02	1.439	0	0
DNA Damage Bypass	R-HSA-73893	3.650001e-02	1.438	0	0
IRAK2 mediated activation of TAK1 complex	R-HSA-937042	3.653521e-02	1.437	0	0
Unwinding of DNA	R-HSA-176974	3.653521e-02	1.437	0	0
HuR (ELAVL1) binds and stabilizes mRNA	R-HSA-450520	3.653521e-02	1.437	0	0
Cellular response to mitochondrial stress	R-HSA-9840373	3.653521e-02	1.437	0	0
Signaling by ROBO receptors	R-HSA-376176	3.838185e-02	1.416	0	0
ER to Golgi Anterograde Transport	R-HSA-199977	3.845022e-02	1.415	0	0
Response to elevated platelet cytosolic Ca2+	R-HSA-76005	3.845477e-02	1.415	0	0
Defective Mismatch Repair Associated With MSH2	R-HSA-5632928	3.870599e-02	1.412	0	0
Breakdown of the nuclear lamina	R-HSA-352238	3.870599e-02	1.412	0	0
Translesion Synthesis by POLH	R-HSA-110320	3.951448e-02	1.403	0	0
Formation of the dystrophin-glycoprotein complex (DGC)	R-HSA-9913351	3.982496e-02	1.400	0	0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	R-HSA-975163	3.986651e-02	1.399	0	0
Synthesis And Processing Of GAG, GAGPOL Polyproteins	R-HSA-174495	3.986651e-02	1.399	0	0
Degradation of AXIN	R-HSA-4641257	4.081134e-02	1.389	0	0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	R-HSA-9762114	4.081134e-02	1.389	0	0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	R-HSA-1234176	4.468656e-02	1.350	0	0
Hedgehog ligand biogenesis	R-HSA-5358346	4.468656e-02	1.350	0	0
mRNA Editing: A to I Conversion	R-HSA-75064	6.439836e-02	1.191	0	0
C6 deamination of adenosine	R-HSA-75102	6.439836e-02	1.191	0	0
Signalling to ERK5	R-HSA-198765	6.439836e-02	1.191	0	0
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	R-HSA-1299308	6.439836e-02	1.191	0	0
TGFBR1 LBD Mutants in Cancer	R-HSA-3656535	6.439836e-02	1.191	0	0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	R-HSA-8869496	6.679255e-02	1.175	0	0
Positive Regulation of CDH1 Gene Transcription	R-HSA-9764790	4.654281e-02	1.332	0	0
2-LTR circle formation	R-HSA-164843	4.654281e-02	1.332	0	0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	R-HSA-933543	5.792061e-02	1.237	0	0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	R-HSA-450385	4.818360e-02	1.317	0	0
TRAF6-mediated induction of TAK1 complex within TLR4 complex	R-HSA-937072	4.818360e-02	1.317	0	0
Negative regulation of FLT3	R-HSA-9706369	5.744980e-02	1.241	0	0
Translesion synthesis by POLI	R-HSA-5656121	5.744980e-02	1.241	0	0
Translesion synthesis by POLK	R-HSA-5655862	6.766531e-02	1.170	0	0
Inactivation of APC/C via direct inhibition of the APC/C complex	R-HSA-141430	6.766531e-02	1.170	0	0
Antigen processing: Ub, ATP-independent proteasomal degradation	R-HSA-9912633	6.766531e-02	1.170	0	0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation	R-HSA-9825892	6.250126e-02	1.204	1	1
Gap-filling DNA repair synthesis and ligation in GG-NER	R-HSA-5696397	6.250126e-02	1.204	0	0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	R-HSA-427389	5.697389e-02	1.244	0	0
NEP/NS2 Interacts with the Cellular Export Machinery	R-HSA-168333	5.045896e-02	1.297	0	0
Formation of TC-NER Pre-Incision Complex	R-HSA-6781823	5.573919e-02	1.254	0	0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide	R-HSA-9954709	5.109365e-02	1.292	0	0
Transcription of the HIV genome	R-HSA-167172	5.428430e-02	1.265	0	0
Nucleotide Excision Repair	R-HSA-5696398	6.266056e-02	1.203	0	0
Signaling by NOTCH2	R-HSA-1980145	6.429769e-02	1.192	0	0
NOTCH2 Activation and Transmission of Signal to the Nucleus	R-HSA-2979096	5.412162e-02	1.267	0	0
Formation of Incision Complex in GG-NER	R-HSA-5696395	5.697389e-02	1.244	0	0
SCF(Skp2)-mediated degradation of p27/p21	R-HSA-187577	4.552306e-02	1.342	0	0
Metalloprotease DUBs	R-HSA-5689901	4.979341e-02	1.303	0	0
Signal transduction by L1	R-HSA-445144	4.646210e-02	1.333	0	0
Translesion synthesis by REV1	R-HSA-110312	4.818360e-02	1.317	0	0
Postmitotic nuclear pore complex (NPC) reformation	R-HSA-9615933	4.979341e-02	1.303	0	0
CD28 dependent PI3K/Akt signaling	R-HSA-389357	5.677281e-02	1.246	0	0
Prolonged ERK activation events	R-HSA-169893	5.744980e-02	1.241	0	0
Downstream TCR signaling	R-HSA-202424	5.405453e-02	1.267	0	0
Protein methylation	R-HSA-8876725	4.818360e-02	1.317	0	0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	R-HSA-141405	6.766531e-02	1.170	0	0
Fanconi Anemia Pathway	R-HSA-6783310	5.045896e-02	1.297	0	0
Cargo recognition for clathrin-mediated endocytosis	R-HSA-8856825	5.513665e-02	1.259	0	0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	R-HSA-446388	5.047765e-02	1.297	0	0
Nuclear events stimulated by ALK signaling in cancer	R-HSA-9725371	6.735650e-02	1.172	0	0
Signaling by TGF-beta Receptor Complex in Cancer	R-HSA-3304351	6.679255e-02	1.175	0	0
M-decay: degradation of maternal mRNAs by maternally stored factors	R-HSA-9820841	6.316374e-02	1.200	0	0
Platelet degranulation	R-HSA-114608	6.563790e-02	1.183	0	0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	R-HSA-446343	6.439836e-02	1.191	0	0
Estrogen-dependent gene expression	R-HSA-9018519	4.878964e-02	1.312	0	0
Downregulation of SMAD2/3:SMAD4 transcriptional activity	R-HSA-2173795	4.524183e-02	1.344	0	0
Iron uptake and transport	R-HSA-917937	5.174740e-02	1.286	0	0
Mitophagy	R-HSA-5205647	6.429769e-02	1.192	0	0
Transcriptional regulation by RUNX3	R-HSA-8878159	5.852577e-02	1.233	0	0
Oxidative Stress Induced Senescence	R-HSA-2559580	4.826787e-02	1.316	0	0
Negative regulation of MET activity	R-HSA-6807004	4.646210e-02	1.333	0	0
RNA Polymerase II Transcription	R-HSA-73857	5.321453e-02	1.274	0	0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	R-HSA-8939243	5.112044e-02	1.291	0	0
Export of Viral Ribonucleoproteins from Nucleus	R-HSA-168274	5.573919e-02	1.254	0	0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	R-HSA-8864260	4.552306e-02	1.342	0	0
CaMK IV-mediated phosphorylation of CREB	R-HSA-111932	4.654281e-02	1.332	0	0
InlB-mediated entry of Listeria monocytogenes into host cell	R-HSA-8875360	4.818360e-02	1.317	0	0
SARS-CoV-1 activates/modulates innate immune responses	R-HSA-9692916	4.921739e-02	1.308	0	0
MECP2 regulates neuronal receptors and channels	R-HSA-9022699	4.979341e-02	1.303	0	0
Potential therapeutics for SARS	R-HSA-9679191	4.561002e-02	1.341	0	0
Regulation of expression of SLITs and ROBOs	R-HSA-9010553	5.089612e-02	1.293	0	0
Initiation of Nuclear Envelope (NE) Reformation	R-HSA-2995383	6.250126e-02	1.204	0	0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	R-HSA-8866910	6.766531e-02	1.170	0	0
Transport of Ribonucleoproteins into the Host Nucleus	R-HSA-168271	6.316374e-02	1.200	0	0
Transcriptional Regulation by MECP2	R-HSA-8986944	5.798626e-02	1.237	0	0
NIK-->noncanonical NF-kB signaling	R-HSA-5676590	6.316374e-02	1.200	0	0
IRF3-mediated induction of type I IFN	R-HSA-3270619	4.818360e-02	1.317	0	0
IRE1alpha activates chaperones	R-HSA-381070	6.211010e-02	1.207	0	0
NoRC negatively regulates rRNA expression	R-HSA-427413	6.872558e-02	1.163	0	0
Degradation of CRY and PER proteins	R-HSA-9932298	6.976442e-02	1.156	0	0
XBP1(S) activates chaperone genes	R-HSA-381038	7.058677e-02	1.151	0	0
Integration of provirus	R-HSA-162592	7.064471e-02	1.151	0	0
ABC-family proteins mediated transport	R-HSA-382556	7.101889e-02	1.149	0	0
Glycolysis	R-HSA-70171	7.101889e-02	1.149	0	0
Developmental Lineage of Mammary Stem Cells	R-HSA-9938206	7.160362e-02	1.145	0	0
NOTCH3 Activation and Transmission of Signal to the Nucleus	R-HSA-9013507	7.160362e-02	1.145	0	0
PERK regulates gene expression	R-HSA-381042	7.160801e-02	1.145	0	0
NOTCH1 Intracellular Domain Regulates Transcription	R-HSA-2122947	7.370251e-02	1.133	0	0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	R-HSA-532668	7.370251e-02	1.133	0	0
Signaling by TGFB family members	R-HSA-9006936	7.646409e-02	1.117	0	0
MTOR signalling	R-HSA-165159	7.677926e-02	1.115	0	0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	R-HSA-176407	7.882060e-02	1.103	0	0
FLT3 signaling in disease	R-HSA-9682385	7.940335e-02	1.100	0	0
Cell death signalling via NRAGE, NRIF and NADE	R-HSA-204998	7.963396e-02	1.099	0	0
Signaling by ERBB2 in Cancer	R-HSA-1227990	8.118322e-02	1.091	0	0
Activation of the pre-replicative complex	R-HSA-68962	8.118322e-02	1.091	0	0
Response of EIF2AK1 (HRI) to heme deficiency	R-HSA-9648895	8.142583e-02	1.089	0	0
DNA Replication	R-HSA-69306	8.164219e-02	1.088	0	0
Dual incision in TC-NER	R-HSA-6782135	8.289749e-02	1.081	0	0
AKT phosphorylates targets in the cytosol	R-HSA-198323	8.467247e-02	1.072	0	0
Constitutive Signaling by NOTCH1 HD Domain Mutants	R-HSA-2691232	8.467247e-02	1.072	0	0
Signaling by NOTCH1 HD Domain Mutants in Cancer	R-HSA-2691230	8.467247e-02	1.072	0	0
ESR-mediated signaling	R-HSA-8939211	8.505623e-02	1.070	0	0
TRIF-mediated programmed cell death	R-HSA-2562578	8.518590e-02	1.070	0	0
Uptake and function of diphtheria toxin	R-HSA-5336415	8.518590e-02	1.070	0	0
Cation-coupled Chloride cotransporters	R-HSA-426117	8.518590e-02	1.070	0	0
Translation	R-HSA-72766	8.537653e-02	1.069	0	0
Eukaryotic Translation Termination	R-HSA-72764	8.570211e-02	1.067	0	0
Senescence-Associated Secretory Phenotype (SASP)	R-HSA-2559582	8.592656e-02	1.066	0	0
ER-Phagosome pathway	R-HSA-1236974	8.597229e-02	1.066	0	0
Response of endothelial cells to shear stress	R-HSA-9860931	9.028185e-02	1.044	0	0
EGFR downregulation	R-HSA-182971	9.047916e-02	1.043	0	0
Trafficking of AMPA receptors	R-HSA-399719	9.047916e-02	1.043	0	0
Evasion by RSV of host interferon responses	R-HSA-9833109	9.047916e-02	1.043	0	0
CLEC7A (Dectin-1) signaling	R-HSA-5607764	9.102852e-02	1.041	0	0
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	R-HSA-6781827	9.158816e-02	1.038	0	0
Non-integrin membrane-ECM interactions	R-HSA-3000171	9.158816e-02	1.038	0	0
Diseases of Mismatch Repair (MMR)	R-HSA-5423599	9.422790e-02	1.026	0	0
Loss of MECP2 binding ability to 5mC-DNA	R-HSA-9022538	9.422790e-02	1.026	0	0
Nonsense-Mediated Decay (NMD)	R-HSA-927802	9.441804e-02	1.025	0	0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	R-HSA-975957	9.441804e-02	1.025	0	0
Signaling by NOTCH	R-HSA-157118	9.526475e-02	1.021	0	0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	R-HSA-2894858	9.667955e-02	1.015	0	0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	R-HSA-2894862	9.667955e-02	1.015	0	0
Constitutive Signaling by NOTCH1 PEST Domain Mutants	R-HSA-2644606	9.667955e-02	1.015	0	0
Signaling by NOTCH1 PEST Domain Mutants in Cancer	R-HSA-2644602	9.667955e-02	1.015	0	0
Signaling by NOTCH1 in Cancer	R-HSA-2644603	9.667955e-02	1.015	0	0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	R-HSA-9954714	9.733207e-02	1.012	0	0
Drug resistance of FLT3 mutants	R-HSA-9702506	9.756162e-02	1.011	0	0
FLT3 mutants bind TKIs	R-HSA-9702509	9.756162e-02	1.011	0	0
Defective translocation of RB1 mutants to the nucleus	R-HSA-9661070	9.756162e-02	1.011	0	0
quizartinib-resistant FLT3 mutants	R-HSA-9702620	9.756162e-02	1.011	0	0
linifanib-resistant FLT3 mutants	R-HSA-9702998	9.756162e-02	1.011	0	0
gilteritinib-resistant FLT3 mutants	R-HSA-9702590	9.756162e-02	1.011	0	0
midostaurin-resistant FLT3 mutants	R-HSA-9702600	9.756162e-02	1.011	0	0
APC truncation mutants are not K63 polyubiquitinated	R-HSA-5467333	9.756162e-02	1.011	0	0
pexidartinib-resistant FLT3 mutants	R-HSA-9702605	9.756162e-02	1.011	0	0
sunitinib-resistant FLT3 mutants	R-HSA-9702632	9.756162e-02	1.011	0	0
sorafenib-resistant FLT3 mutants	R-HSA-9702624	9.756162e-02	1.011	0	0
lestaurtinib-resistant FLT3 mutants	R-HSA-9702596	9.756162e-02	1.011	0	0
tamatinib-resistant FLT3 mutants	R-HSA-9703009	9.756162e-02	1.011	0	0
crenolanib-resistant FLT3 mutants	R-HSA-9702581	9.756162e-02	1.011	0	0
KW2449-resistant FLT3 mutants	R-HSA-9702569	9.756162e-02	1.011	0	0
tandutinib-resistant FLT3 mutants	R-HSA-9702636	9.756162e-02	1.011	0	0
semaxanib-resistant FLT3 mutants	R-HSA-9702577	9.756162e-02	1.011	0	0
ponatinib-resistant FLT3 mutants	R-HSA-9702614	9.756162e-02	1.011	0	0
RUNX1 regulates transcription of genes involved in differentiation of HSCs	R-HSA-8939236	9.782576e-02	1.010	0	0
HCMV Infection	R-HSA-9609646	9.993344e-02	1.000	0	0
HDR through MMEJ (alt-NHEJ)	R-HSA-5685939	9.994524e-02	1.000	0	0
Frs2-mediated activation	R-HSA-170968	9.994524e-02	1.000	0	0
Regulation of TP53 Activity through Association with Co-factors	R-HSA-6804759	9.994524e-02	1.000	0	0
Somitogenesis	R-HSA-9824272	1.003167e-01	0.999	0	0
DAG and IP3 signaling	R-HSA-1489509	1.003167e-01	0.999	0	0
Asymmetric localization of PCP proteins	R-HSA-4608870	1.003167e-01	0.999	0	0
Dectin-1 mediated noncanonical NF-kB signaling	R-HSA-5607761	1.003167e-01	0.999	0	0
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	1.010558e-01	0.995	0	0
Meiotic synapsis	R-HSA-1221632	1.027151e-01	0.988	0	0
B-WICH complex positively regulates rRNA expression	R-HSA-5250924	1.027151e-01	0.988	0	0
Cellular response to starvation	R-HSA-9711097	1.028494e-01	0.988	0	0
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	1.038678e-01	0.984	0	0
The NLRP3 inflammasome	R-HSA-844456	1.038678e-01	0.984	0	0
Maturation of nucleoprotein	R-HSA-9694631	1.038678e-01	0.984	0	0
STING mediated induction of host immune responses	R-HSA-1834941	1.038678e-01	0.984	0	0
Cellular responses to mechanical stimuli	R-HSA-9855142	1.050896e-01	0.978	0	0
SARS-CoV-2 activates/modulates innate and adaptive immune responses	R-HSA-9705671	1.074041e-01	0.969	0	0
Regulation of PD-L1(CD274) Post-translational modification	R-HSA-9909615	1.106884e-01	0.956	0	0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling	R-HSA-442742	1.107774e-01	0.956	0	0
Glutamate binding, activation of AMPA receptors and synaptic plasticity	R-HSA-399721	1.107774e-01	0.956	0	0
Regulation of MECP2 expression and activity	R-HSA-9022692	1.107774e-01	0.956	0	0
SARS-CoV-2 modulates host translation machinery	R-HSA-9754678	1.108725e-01	0.955	0	0
RNA Polymerase I Transcription	R-HSA-73864	1.114924e-01	0.953	0	0
Degradation of beta-catenin by the destruction complex	R-HSA-195253	1.118916e-01	0.951	0	0
SRP-dependent cotranslational protein targeting to membrane	R-HSA-1799339	1.125971e-01	0.948	0	0
Regulation of KIT signaling	R-HSA-1433559	1.163910e-01	0.934	0	0
TP53 Regulates Metabolic Genes	R-HSA-5628897	1.164797e-01	0.934	0	0
Transcription of E2F targets under negative control by DREAM complex	R-HSA-1362277	1.176983e-01	0.929	0	0
Co-inhibition by CTLA4	R-HSA-389513	1.176983e-01	0.929	0	0
TAK1-dependent IKK and NF-kappa-B activation	R-HSA-445989	1.180642e-01	0.928	0	0
Retrograde transport at the Trans-Golgi-Network	R-HSA-6811440	1.180642e-01	0.928	0	0
Interleukin-1 signaling	R-HSA-9020702	1.207451e-01	0.918	0	0
NFE2L2 regulating anti-oxidant/detoxification enzymes	R-HSA-9818027	1.217577e-01	0.915	0	0
Regulation of T cell activation by CD28 family	R-HSA-388841	1.229933e-01	0.910	0	0
Platelet activation, signaling and aggregation	R-HSA-76002	1.244312e-01	0.905	0	0
Signaling by Interleukins	R-HSA-449147	1.258568e-01	0.900	0	0
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	1.260682e-01	0.899	0	0
TICAM1 deficiency - HSE	R-HSA-5602566	1.856102e-01	0.731	0	0
SARS-CoV-1 targets PDZ proteins in cell-cell junction	R-HSA-9692912	1.856102e-01	0.731	0	0
Defective DNA double strand break response due to BARD1 loss of function	R-HSA-9699150	1.856102e-01	0.731	0	0
Defective Mismatch Repair Associated With MSH3	R-HSA-5632927	1.856102e-01	0.731	0	0
Defective DNA double strand break response due to BRCA1 loss of function	R-HSA-9663199	1.856102e-01	0.731	0	0
Hereditary fructose intolerance	R-HSA-5657560	1.856102e-01	0.731	0	0
FLT3 signaling through SRC family kinases	R-HSA-9706374	1.271438e-01	0.896	0	0
NFE2L2 regulating ER-stress associated genes	R-HSA-9818035	1.271438e-01	0.896	0	0
PLCG1 events in ERBB2 signaling	R-HSA-1251932	1.271438e-01	0.896	0	0
TGFBR1 KD Mutants in Cancer	R-HSA-3656532	1.271438e-01	0.896	0	0
Signaling by MAP2K mutants	R-HSA-9652169	1.271438e-01	0.896	0	0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	R-HSA-69200	1.271438e-01	0.896	0	0
SMAC (DIABLO) binds to IAPs	R-HSA-111463	1.622608e-01	0.790	0	0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes	R-HSA-111464	1.622608e-01	0.790	0	0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	R-HSA-9673768	1.622608e-01	0.790	0	0
SMAD2/3 Phosphorylation Motif Mutants in Cancer	R-HSA-3304356	1.622608e-01	0.790	0	0
ALK mutants bind TKIs	R-HSA-9700645	1.274221e-01	0.895	0	0
SMAC, XIAP-regulated apoptotic response	R-HSA-111469	1.988366e-01	0.702	0	0
CDH11 homotypic and heterotypic interactions	R-HSA-9833576	1.988366e-01	0.702	0	0
IkBA variant leads to EDA-ID	R-HSA-5603029	1.988366e-01	0.702	0	0
Activation of caspases through apoptosome-mediated cleavage	R-HSA-111459	1.988366e-01	0.702	0	0
MET activates RAP1 and RAC1	R-HSA-8875555	1.508352e-01	0.821	0	0
PTK6 promotes HIF1A stabilization	R-HSA-8857538	2.362530e-01	0.627	0	0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	R-HSA-450513	1.339270e-01	0.873	0	0
Phosphorylation of the APC/C	R-HSA-176412	1.524619e-01	0.817	1	1
Activation of RAC1	R-HSA-428540	2.011472e-01	0.696	0	0
Condensation of Prometaphase Chromosomes	R-HSA-2514853	2.011472e-01	0.696	0	0
PD-L1(CD274) glycosylation and translocation to plasma membrane	R-HSA-9931295	1.323476e-01	0.878	0	0
TNFR1-induced proapoptotic signaling	R-HSA-5357786	1.323476e-01	0.878	0	0
Processing of Intronless Pre-mRNAs	R-HSA-77595	1.718986e-01	0.765	0	0
NOTCH2 intracellular domain regulates transcription	R-HSA-2197563	2.276152e-01	0.643	0	0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors	R-HSA-9820865	2.276152e-01	0.643	0	0
Scavenging by Class F Receptors	R-HSA-3000484	2.276152e-01	0.643	0	0
Unblocking of NMDA receptors, glutamate binding and activation	R-HSA-438066	1.477687e-01	0.830	0	0
Ras activation upon Ca2+ influx through NMDA receptor	R-HSA-442982	1.477687e-01	0.830	0	0
Constitutive Signaling by EGFRvIII	R-HSA-5637810	1.921356e-01	0.716	0	0
Signaling by EGFRvIII in Cancer	R-HSA-5637812	1.921356e-01	0.716	0	0
GAB1 signalosome	R-HSA-180292	2.130693e-01	0.671	0	0
Signaling by ERBB2 KD Mutants	R-HSA-9664565	1.546824e-01	0.811	0	0
Termination of translesion DNA synthesis	R-HSA-5656169	1.546824e-01	0.811	0	0
RAF activation	R-HSA-5673000	1.332725e-01	0.875	0	0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex	R-HSA-9843970	1.332725e-01	0.875	0	0
SHC1 events in ERBB2 signaling	R-HSA-1250196	1.690553e-01	0.772	0	0
Signaling by ERBB2 TMD/JMD mutants	R-HSA-9665686	1.981282e-01	0.703	0	0
Pre-NOTCH Processing in Golgi	R-HSA-1912420	2.345956e-01	0.630	0	0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells	R-HSA-9927418	1.472623e-01	0.832	0	0
G0 and Early G1	R-HSA-1538133	1.993605e-01	0.700	0	0
Gap-filling DNA repair synthesis and ligation in TC-NER	R-HSA-6782210	1.282509e-01	0.892	0	0
RNA Polymerase I Transcription Termination	R-HSA-73863	2.533825e-01	0.596	0	0
Formation of RNA Pol II elongation complex	R-HSA-112382	1.692451e-01	0.771	0	0
Regulation of PD-L1(CD274) transcription	R-HSA-9909649	1.456619e-01	0.837	0	0
RNA Polymerase II Transcription Elongation	R-HSA-75955	1.805638e-01	0.743	0	0
Viral mRNA Translation	R-HSA-192823	2.010303e-01	0.697	0	0
Regulation of PD-L1(CD274) expression	R-HSA-9909648	1.343676e-01	0.872	0	0
Co-inhibition by PD-1	R-HSA-389948	2.541168e-01	0.595	0	0
PI3K/AKT Signaling in Cancer	R-HSA-2219528	1.413984e-01	0.850	0	0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2	R-HSA-9844594	2.124072e-01	0.673	0	0
Transcriptional regulation of brown and beige adipocyte differentiation	R-HSA-9843743	2.124072e-01	0.673	0	0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	R-HSA-110313	2.270316e-01	0.644	0	0
NOTCH3 Intracellular Domain Regulates Transcription	R-HSA-9013508	1.690553e-01	0.772	0	0
Signaling by EGFR	R-HSA-177929	1.282509e-01	0.892	0	0
Sensing of DNA Double Strand Breaks	R-HSA-5693548	2.011472e-01	0.696	0	0
NOTCH4 Intracellular Domain Regulates Transcription	R-HSA-9013695	1.323476e-01	0.878	0	0
DNA strand elongation	R-HSA-69190	1.993605e-01	0.700	0	0
Nuclear RNA decay	R-HSA-9930044	2.152145e-01	0.667	0	0
Meiotic recombination	R-HSA-912446	1.582703e-01	0.801	0	0
Co-stimulation by CD28	R-HSA-389356	1.275397e-01	0.894	0	0
Chromosome Maintenance	R-HSA-73886	1.619160e-01	0.791	0	0
Signaling by CSF1 (M-CSF) in myeloid cells	R-HSA-9680350	1.332725e-01	0.875	0	0
RIP-mediated NFkB activation via ZBP1	R-HSA-1810476	1.339270e-01	0.873	0	0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	R-HSA-6814122	2.481170e-01	0.605	0	0
DNA Damage/Telomere Stress Induced Senescence	R-HSA-2559586	1.883925e-01	0.725	0	0
Long-term potentiation	R-HSA-9620244	2.160851e-01	0.665	0	0
FOXO-mediated transcription	R-HSA-9614085	2.458337e-01	0.609	0	0
MyD88-independent TLR4 cascade	R-HSA-166166	1.313417e-01	0.882	0	0
RNA Polymerase I Promoter Clearance	R-HSA-73854	1.614453e-01	0.792	0	0
TRIF (TICAM1)-mediated TLR4 signaling	R-HSA-937061	1.313417e-01	0.882	0	0
TCF dependent signaling in response to WNT	R-HSA-201681	1.993880e-01	0.700	0	0
SLC15A4:TASL-dependent IRF5 activation	R-HSA-9860276	1.988366e-01	0.702	0	0
Modulation of host responses by IFN-stimulated genes	R-HSA-9909505	1.921356e-01	0.716	0	0
Negative regulators of DDX58/IFIH1 signaling	R-HSA-936440	1.839607e-01	0.735	0	0
Aryl hydrocarbon receptor signalling	R-HSA-8937144	1.988366e-01	0.702	0	0
Transcriptional regulation by small RNAs	R-HSA-5578749	2.052490e-01	0.688	0	0
Formation of paraxial mesoderm	R-HSA-9793380	1.775883e-01	0.751	0	0
MAPK family signaling cascades	R-HSA-5683057	1.314071e-01	0.881	0	0
Signaling by NOTCH1	R-HSA-1980143	2.499237e-01	0.602	0	0
Ca-dependent events	R-HSA-111996	1.472623e-01	0.832	0	0
Signaling by MET	R-HSA-6806834	1.997116e-01	0.700	0	0
Inhibition of PKR	R-HSA-169131	1.856102e-01	0.731	0	0
Loss of Function of SMAD2/3 in Cancer	R-HSA-3304349	1.988366e-01	0.702	0	0
Negative regulation of NMDA receptor-mediated neuronal transmission	R-HSA-9617324	1.477687e-01	0.830	0	0
Regulation of FZD by ubiquitination	R-HSA-4641263	1.921356e-01	0.716	0	0
VEGFR2 mediated cell proliferation	R-HSA-5218921	2.160851e-01	0.665	0	0
Glutamate Neurotransmitter Release Cycle	R-HSA-210500	2.345243e-01	0.630	0	0
Viral Messenger RNA Synthesis	R-HSA-168325	1.775883e-01	0.751	0	0
Developmental Biology	R-HSA-1266738	1.556982e-01	0.808	1	0
MyD88 cascade initiated on plasma membrane	R-HSA-975871	2.359157e-01	0.627	0	0
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	2.359157e-01	0.627	0	0
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	2.359157e-01	0.627	0	0
Calmodulin induced events	R-HSA-111933	1.578304e-01	0.802	0	0
Mitochondrial unfolded protein response (UPRmt)	R-HSA-9841251	1.276756e-01	0.894	0	0
RAF/MAP kinase cascade	R-HSA-5673001	2.440004e-01	0.613	0	0
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	2.209503e-01	0.656	0	0
CaM pathway	R-HSA-111997	1.578304e-01	0.802	0	0
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	2.481854e-01	0.605	0	0
Cellular response to hypoxia	R-HSA-1234174	1.367229e-01	0.864	0	0
Regulation of innate immune responses to cytosolic DNA	R-HSA-3134975	1.718986e-01	0.765	0	0
MAP kinase activation	R-HSA-450294	1.775883e-01	0.751	0	0
Cyclin D associated events in G1	R-HSA-69231	1.706411e-01	0.768	0	0
G1 Phase	R-HSA-69236	1.706411e-01	0.768	0	0
Epithelial-Mesenchymal Transition (EMT) during gastrulation	R-HSA-9758919	1.988366e-01	0.702	0	0
Disorders of Nervous System Development	R-HSA-9697154	2.276152e-01	0.643	0	0
Pervasive developmental disorders	R-HSA-9005895	2.276152e-01	0.643	0	0
Loss of function of MECP2 in Rett syndrome	R-HSA-9005891	2.276152e-01	0.643	0	0
Regulation of RAS by GAPs	R-HSA-5658442	1.476531e-01	0.831	0	0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	R-HSA-168643	1.280875e-01	0.892	0	0
Activated NOTCH1 Transmits Signal to the Nucleus	R-HSA-2122948	2.345243e-01	0.630	0	0
Generic Transcription Pathway	R-HSA-212436	2.257453e-01	0.646	0	0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	R-HSA-2173793	2.164308e-01	0.665	0	0
Immune System	R-HSA-168256	1.525205e-01	0.817	0	0
Regulation of pyruvate metabolism	R-HSA-9861718	1.955718e-01	0.709	0	0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	R-HSA-6804115	1.639102e-01	0.785	0	0
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	2.052490e-01	0.688	0	0
Negative regulation of MAPK pathway	R-HSA-5675221	1.361991e-01	0.866	0	0
Signaling by NTRK1 (TRKA)	R-HSA-187037	2.237259e-01	0.650	0	0
Neurotransmitter receptors and postsynaptic signal transmission	R-HSA-112314	2.191364e-01	0.659	0	0
p75NTR negatively regulates cell cycle via SC1	R-HSA-193670	1.271438e-01	0.896	0	0
Negative feedback regulation of MAPK pathway	R-HSA-5674499	1.988366e-01	0.702	0	0
NOD1/2 Signaling Pathway	R-HSA-168638	2.481170e-01	0.605	0	0
TP53 Regulates Transcription of Cell Cycle Genes	R-HSA-6791312	2.289676e-01	0.640	0	0
NGF-stimulated transcription	R-HSA-9031628	2.218931e-01	0.654	0	0
Signaling by ERBB4	R-HSA-1236394	2.271516e-01	0.644	0	0
PECAM1 interactions	R-HSA-210990	1.754833e-01	0.756	0	0
Sensory processing of sound by inner hair cells of the cochlea	R-HSA-9662360	1.644238e-01	0.784	0	0
tRNA processing in the nucleus	R-HSA-6784531	1.883925e-01	0.725	0	0
Selenocysteine synthesis	R-HSA-2408557	1.837738e-01	0.736	0	0
Regulation of RUNX2 expression and activity	R-HSA-8939902	1.775883e-01	0.751	0	0
Prevention of phagosomal-lysosomal fusion	R-HSA-9636383	1.323476e-01	0.878	0	0
ZBP1(DAI) mediated induction of type I IFNs	R-HSA-1606322	2.130693e-01	0.671	0	0
Oncogene Induced Senescence	R-HSA-2559585	1.453036e-01	0.838	0	0
CREB phosphorylation	R-HSA-199920	2.362530e-01	0.627	0	0
Assembly Of The HIV Virion	R-HSA-175474	1.477687e-01	0.830	0	0
Plasma lipoprotein clearance	R-HSA-8964043	1.981459e-01	0.703	0	0
Glucose metabolism	R-HSA-70326	1.974529e-01	0.705	0	0
Response of Mtb to phagocytosis	R-HSA-9637690	1.587484e-01	0.799	0	0
RMTs methylate histone arginines	R-HSA-3214858	1.706411e-01	0.768	0	0
ER Quality Control Compartment (ERQC)	R-HSA-901032	1.276756e-01	0.894	0	0
Regulation of CDH19 Expression and Function	R-HSA-9764302	1.988366e-01	0.702	0	0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	R-HSA-975110	1.718986e-01	0.765	0	0
Spry regulation of FGF signaling	R-HSA-1295596	1.339270e-01	0.873	0	0
Suppression of phagosomal maturation	R-HSA-9637687	2.345243e-01	0.630	0	0
Apoptosis induced DNA fragmentation	R-HSA-140342	1.508352e-01	0.821	0	0
Signaling by PDGFR in disease	R-HSA-9671555	1.477687e-01	0.830	0	0
Interleukin-3, Interleukin-5 and GM-CSF signaling	R-HSA-512988	1.472623e-01	0.832	0	0
RUNX2 regulates genes involved in cell migration	R-HSA-8941332	1.754833e-01	0.756	0	0
Regulation of BACH1 activity	R-HSA-9708530	1.524619e-01	0.817	0	0
Sensory processing of sound by outer hair cells of the cochlea	R-HSA-9662361	1.282509e-01	0.892	0	0
Translation of Structural Proteins	R-HSA-9683701	1.361991e-01	0.866	0	0
Glycogen storage diseases	R-HSA-3229121	1.921356e-01	0.716	0	0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	R-HSA-9659787	2.546854e-01	0.594	0	0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	R-HSA-9661069	2.546854e-01	0.594	0	0
Replication of the SARS-CoV-1 genome	R-HSA-9682706	2.546854e-01	0.594	0	0
Maturation of nucleoprotein	R-HSA-9683610	2.546854e-01	0.594	0	0
Formation of ATP by chemiosmotic coupling	R-HSA-163210	2.566110e-01	0.591	0	0
BBSome-mediated cargo-targeting to cilium	R-HSA-5620922	2.566110e-01	0.591	0	0
Glycogen synthesis	R-HSA-3322077	2.566110e-01	0.591	0	0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	2.568992e-01	0.590	0	0
Antigen processing-Cross presentation	R-HSA-1236975	2.568992e-01	0.590	0	0
Interferon alpha/beta signaling	R-HSA-909733	2.575457e-01	0.589	0	0
Regulated Necrosis	R-HSA-5218859	2.587327e-01	0.587	0	0
PTEN Loss of Function in Cancer	R-HSA-5674404	2.650727e-01	0.577	0	0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)	R-HSA-5619054	2.650727e-01	0.577	0	0
IKBKB deficiency causes SCID	R-HSA-5602636	2.650727e-01	0.577	0	0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3	R-HSA-5083628	2.650727e-01	0.577	0	0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	R-HSA-5603027	2.650727e-01	0.577	0	0
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)	R-HSA-5619039	2.650727e-01	0.577	0	0
TRAF3 deficiency - HSE	R-HSA-5602571	2.650727e-01	0.577	0	0
Manipulation of host energy metabolism	R-HSA-9636667	2.650727e-01	0.577	0	0
Signaling by NTRKs	R-HSA-166520	2.661225e-01	0.575	0	0
MyD88 dependent cascade initiated on endosome	R-HSA-975155	2.667378e-01	0.574	0	0
Inflammasomes	R-HSA-622312	2.725962e-01	0.564	0	0
ABC transporter disorders	R-HSA-5619084	2.734620e-01	0.563	0	0
Disinhibition of SNARE formation	R-HSA-114516	2.739980e-01	0.562	0	0
Microbial modulation of RIPK1-mediated regulated necrosis	R-HSA-9686347	2.739980e-01	0.562	0	0
CHL1 interactions	R-HSA-447041	2.739980e-01	0.562	0	0
RUNX3 Regulates Immune Response and Cell Migration	R-HSA-8949275	2.739980e-01	0.562	0	0
Adaptive Immune System	R-HSA-1280218	2.743562e-01	0.562	0	0
RNA polymerase II transcribes snRNA genes	R-HSA-6807505	2.749765e-01	0.561	0	0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1	R-HSA-450321	2.790143e-01	0.554	0	0
Early Phase of HIV Life Cycle	R-HSA-162594	2.790143e-01	0.554	0	0
PLC beta mediated events	R-HSA-112043	2.815278e-01	0.550	0	0
SARS-CoV-1 Genome Replication and Transcription	R-HSA-9679514	2.821684e-01	0.549	0	0
Lysosome Vesicle Biogenesis	R-HSA-432720	2.823240e-01	0.549	0	0
Interleukin-17 signaling	R-HSA-448424	2.839236e-01	0.547	0	0
Sensory processing of sound	R-HSA-9659379	2.854845e-01	0.544	0	0
MAPK1/MAPK3 signaling	R-HSA-5684996	2.867263e-01	0.543	0	0
Proteasome assembly	R-HSA-9907900	2.885367e-01	0.540	0	0
Endosomal Sorting Complex Required For Transport (ESCRT)	R-HSA-917729	2.921022e-01	0.534	0	0
Transcriptional regulation by RUNX2	R-HSA-8878166	2.962184e-01	0.528	0	0
Hedgehog 'on' state	R-HSA-5632684	2.967738e-01	0.528	0	0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	R-HSA-2173796	2.998072e-01	0.523	0	0
Interleukin-1 family signaling	R-HSA-446652	3.005587e-01	0.522	0	0
activated TAK1 mediates p38 MAPK activation	R-HSA-450302	3.017071e-01	0.520	0	0
Inactivation of CSF3 (G-CSF) signaling	R-HSA-9705462	3.017071e-01	0.520	0	0
ERBB2 Regulates Cell Motility	R-HSA-6785631	3.098883e-01	0.509	0	0
DCC mediated attractive signaling	R-HSA-418885	3.098883e-01	0.509	0	0
Regulation by c-FLIP	R-HSA-3371378	3.116517e-01	0.506	0	0
RSK activation	R-HSA-444257	3.116517e-01	0.506	0	0
Nef mediated downregulation of MHC class I complex cell surface expression	R-HSA-164940	3.116517e-01	0.506	0	0
Dimerization of procaspase-8	R-HSA-69416	3.116517e-01	0.506	0	0
Formyl peptide receptors bind formyl peptides and many other ligands	R-HSA-444473	3.116517e-01	0.506	0	0
Astrocytic Glutamate-Glutamine Uptake And Metabolism	R-HSA-210455	3.116517e-01	0.506	0	0
Neurotransmitter uptake and metabolism In glial cells	R-HSA-112313	3.116517e-01	0.506	0	0
ROBO receptors bind AKAP5	R-HSA-9010642	3.116517e-01	0.506	0	0
Axonal growth inhibition (RHOA activation)	R-HSA-193634	3.116517e-01	0.506	0	0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde	R-HSA-442729	3.116517e-01	0.506	0	0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells	R-HSA-8939246	3.116517e-01	0.506	0	0
Beta-catenin independent WNT signaling	R-HSA-3858494	3.128856e-01	0.505	0	0
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	3.169849e-01	0.499	0	0
mRNA Splicing - Minor Pathway	R-HSA-72165	3.206417e-01	0.494	0	0
Ion transport by P-type ATPases	R-HSA-936837	3.229254e-01	0.491	0	0
Budding and maturation of HIV virion	R-HSA-162588	3.317443e-01	0.479	0	0
Post-translational protein phosphorylation	R-HSA-8957275	3.318487e-01	0.479	0	0
Reproduction	R-HSA-1474165	3.341986e-01	0.476	0	0
Cross-presentation of soluble exogenous antigens (endosomes)	R-HSA-1236978	3.353150e-01	0.475	0	0
Signaling by ALK	R-HSA-201556	3.353150e-01	0.475	0	0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1	R-HSA-5083633	3.367861e-01	0.473	0	0
TGFBR2 Kinase Domain Mutants in Cancer	R-HSA-3645790	3.367861e-01	0.473	0	0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2	R-HSA-5083629	3.367861e-01	0.473	0	0
Loss of Function of TGFBR2 in Cancer	R-HSA-3642278	3.367861e-01	0.473	0	0
Regulation of cortical dendrite branching	R-HSA-8985801	3.367861e-01	0.473	0	0
Activation, myristolyation of BID and translocation to mitochondria	R-HSA-75108	3.367861e-01	0.473	0	0
ATF6B (ATF6-beta) activates chaperones	R-HSA-8874177	3.367861e-01	0.473	0	0
Detoxification of Reactive Oxygen Species	R-HSA-3299685	3.373356e-01	0.472	0	0
Ion homeostasis	R-HSA-5578775	3.373356e-01	0.472	0	0
Caspase activation via Death Receptors in the presence of ligand	R-HSA-140534	3.376838e-01	0.471	0	0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	R-HSA-1362300	3.376838e-01	0.471	0	0
GRB2:SOS provides linkage to MAPK signaling for Integrins	R-HSA-354194	3.376838e-01	0.471	0	0
WNT5A-dependent internalization of FZD4	R-HSA-5099900	3.376838e-01	0.471	0	0
KSRP (KHSRP) binds and destabilizes mRNA	R-HSA-450604	3.376838e-01	0.471	0	0
Class I peroxisomal membrane protein import	R-HSA-9603798	3.376838e-01	0.471	0	0
Transport to the Golgi and subsequent modification	R-HSA-948021	3.399542e-01	0.469	0	0
HATs acetylate histones	R-HSA-3214847	3.433316e-01	0.464	0	0
Syndecan interactions	R-HSA-3000170	3.475879e-01	0.459	0	0
ARMS-mediated activation	R-HSA-170984	3.488729e-01	0.457	0	0
Lipophagy	R-HSA-9613354	3.488729e-01	0.457	0	0
MASTL Facilitates Mitotic Progression	R-HSA-2465910	3.488729e-01	0.457	0	0
CASP8 activity is inhibited	R-HSA-5218900	3.488729e-01	0.457	0	0
mRNA Editing	R-HSA-75072	3.488729e-01	0.457	0	0
p75NTR regulates axonogenesis	R-HSA-193697	3.488729e-01	0.457	0	0
GP1b-IX-V activation signalling	R-HSA-430116	3.488729e-01	0.457	0	0
NOTCH4 Activation and Transmission of Signal to the Nucleus	R-HSA-9013700	3.488729e-01	0.457	0	0
Zinc influx into cells by the SLC39 gene family	R-HSA-442380	3.488729e-01	0.457	0	0
NFE2L2 regulating MDR associated enzymes	R-HSA-9818032	3.488729e-01	0.457	0	0
Respiratory syncytial virus genome replication	R-HSA-9834752	3.488729e-01	0.457	0	0
Butyrophilin (BTN) family interactions	R-HSA-8851680	3.488729e-01	0.457	0	0
Neddylation	R-HSA-8951664	3.500519e-01	0.456	0	0
Regulation of ornithine decarboxylase (ODC)	R-HSA-350562	3.517607e-01	0.454	0	0
Generation of second messenger molecules	R-HSA-202433	3.532545e-01	0.452	0	0
Nuclear signaling by ERBB4	R-HSA-1251985	3.532545e-01	0.452	0	0
Interferon gamma signaling	R-HSA-877300	3.637541e-01	0.439	0	0
G-protein mediated events	R-HSA-112040	3.654027e-01	0.437	0	0
mRNA decay by 5' to 3' exoribonuclease	R-HSA-430039	3.654085e-01	0.437	0	0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	R-HSA-6804114	3.654085e-01	0.437	0	0
Disorders of Developmental Biology	R-HSA-9675151	3.654085e-01	0.437	0	0
Deadenylation of mRNA	R-HSA-429947	3.706011e-01	0.431	0	0
Processing of Capped Intronless Pre-mRNA	R-HSA-75067	3.706011e-01	0.431	0	0
Neurodegenerative Diseases	R-HSA-8863678	3.706011e-01	0.431	0	0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	R-HSA-8862803	3.706011e-01	0.431	0	0
Transcriptional Regulation by VENTX	R-HSA-8853884	3.712626e-01	0.430	0	0
Integrin signaling	R-HSA-354192	3.718311e-01	0.430	0	0
Translation of Structural Proteins	R-HSA-9694635	3.763662e-01	0.424	0	0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	R-HSA-8936459	3.797059e-01	0.421	0	0
Deadenylation-dependent mRNA decay	R-HSA-429914	3.830259e-01	0.417	0	0
EGFR Transactivation by Gastrin	R-HSA-2179392	3.853875e-01	0.414	0	0
Regulation of CDH11 function	R-HSA-9762292	3.853875e-01	0.414	0	0
Defective RIPK1-mediated regulated necrosis	R-HSA-9693928	3.853875e-01	0.414	0	0
Ion influx/efflux at host-pathogen interface	R-HSA-6803544	3.853875e-01	0.414	0	0
MECP2 regulates transcription of neuronal ligands	R-HSA-9022702	3.853875e-01	0.414	0	0
Assembly and release of respiratory syncytial virus (RSV) virions	R-HSA-9820962	3.853875e-01	0.414	0	0
Tandem pore domain potassium channels	R-HSA-1296346	3.853875e-01	0.414	0	0
Intra-Golgi traffic	R-HSA-6811438	3.892992e-01	0.410	0	0
EGR2 and SOX10-mediated initiation of Schwann cell myelination	R-HSA-9619665	3.919011e-01	0.407	0	0
PI3K events in ERBB2 signaling	R-HSA-1963642	3.929310e-01	0.406	0	0
p130Cas linkage to MAPK signaling for integrins	R-HSA-372708	3.929310e-01	0.406	0	0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	R-HSA-5358565	3.929310e-01	0.406	0	0
Replication of the SARS-CoV-2 genome	R-HSA-9694686	3.929310e-01	0.406	0	0
Tight junction interactions	R-HSA-420029	3.935551e-01	0.405	0	0
DDX58/IFIH1-mediated induction of interferon-alpha/beta	R-HSA-168928	3.942152e-01	0.404	0	0
Inositol phosphate metabolism	R-HSA-1483249	3.970534e-01	0.401	0	0
Pyruvate metabolism	R-HSA-70268	3.987161e-01	0.399	0	0
Regulation of MITF-M dependent genes involved in metabolism	R-HSA-9854907	4.015056e-01	0.396	0	0
Axonal growth stimulation	R-HSA-209563	4.015056e-01	0.396	0	0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins	R-HSA-5368598	4.015056e-01	0.396	0	0
MET activates PTPN11	R-HSA-8865999	4.015056e-01	0.396	0	0
Activation of BIM and translocation to mitochondria	R-HSA-111446	4.015056e-01	0.396	0	0
MET interacts with TNS proteins	R-HSA-8875513	4.015056e-01	0.396	0	0
Intracellular oxygen transport	R-HSA-8981607	4.015056e-01	0.396	0	0
FasL/ CD95L signaling	R-HSA-75157	4.015056e-01	0.396	0	0
Diseases of programmed cell death	R-HSA-9645723	4.115907e-01	0.386	0	0
Uptake and actions of bacterial toxins	R-HSA-5339562	4.192822e-01	0.377	0	0
Mismatch Repair	R-HSA-5358508	4.201344e-01	0.377	0	0
Serotonin Neurotransmitter Release Cycle	R-HSA-181429	4.201344e-01	0.377	0	0
Formation of the posterior neural plate	R-HSA-9832991	4.209794e-01	0.376	0	0
vRNP Assembly	R-HSA-192905	4.209794e-01	0.376	0	0
RHOBTB3 ATPase cycle	R-HSA-9706019	4.209794e-01	0.376	0	0
Synthesis of PI	R-HSA-1483226	4.209794e-01	0.376	0	0
Suppression of apoptosis	R-HSA-9635465	4.209794e-01	0.376	0	0
TBC/RABGAPs	R-HSA-8854214	4.253063e-01	0.371	0	0
Signaling by WNT	R-HSA-195721	4.289334e-01	0.368	0	0
Signalling to ERKs	R-HSA-187687	4.318372e-01	0.365	0	0
Cristae formation	R-HSA-8949613	4.389964e-01	0.358	0	0
Defective Intrinsic Pathway for Apoptosis	R-HSA-9734009	4.389964e-01	0.358	0	0
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	4.398649e-01	0.357	0	0
Infectious disease	R-HSA-5663205	4.401003e-01	0.356	0	0
Signaling by the B Cell Receptor (BCR)	R-HSA-983705	4.440307e-01	0.353	0	0
Abortive elongation of HIV-1 transcript in the absence of Tat	R-HSA-167242	4.469160e-01	0.350	0	0
E2F mediated regulation of DNA replication	R-HSA-113510	4.469160e-01	0.350	0	0
Rap1 signalling	R-HSA-392517	4.469160e-01	0.350	0	0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes	R-HSA-9856532	4.469160e-01	0.350	0	0
SARS-CoV-2 Genome Replication and Transcription	R-HSA-9694682	4.469160e-01	0.350	0	0
Gene Silencing by RNA	R-HSA-211000	4.487619e-01	0.348	0	0
PRC2 methylates histones and DNA	R-HSA-212300	4.516090e-01	0.345	0	0
Developmental Cell Lineages	R-HSA-9734767	4.545852e-01	0.342	0	0
Inhibition of replication initiation of damaged DNA by RB1/E2F1	R-HSA-113501	4.554808e-01	0.342	0	0
Cytochrome c-mediated apoptotic response	R-HSA-111461	4.554808e-01	0.342	0	0
NFE2L2 regulates pentose phosphate pathway genes	R-HSA-9818028	4.554808e-01	0.342	0	0
RUNX3 regulates BCL2L11 (BIM) transcription	R-HSA-8952158	4.599129e-01	0.337	0	0
Inhibition of TSC complex formation by PKB	R-HSA-165181	4.599129e-01	0.337	0	0
GRB7 events in ERBB2 signaling	R-HSA-1306955	4.599129e-01	0.337	0	0
Defective LFNG causes SCDO3	R-HSA-5083630	4.599129e-01	0.337	0	0
Extrinsic Pathway of Fibrin Clot Formation	R-HSA-140834	4.599129e-01	0.337	0	0
Regulation of gap junction activity	R-HSA-191650	4.599129e-01	0.337	0	0
TNFR1-mediated ceramide production	R-HSA-5626978	4.599129e-01	0.337	0	0
SARS-CoV-1-mediated effects on programmed cell death	R-HSA-9692913	4.599129e-01	0.337	0	0
Activation of NOXA and translocation to mitochondria	R-HSA-111448	4.599129e-01	0.337	0	0
NADE modulates death signalling	R-HSA-205025	4.599129e-01	0.337	0	0
Formation of the HIV-1 Early Elongation Complex	R-HSA-167158	4.613538e-01	0.336	0	0
Formation of the Early Elongation Complex	R-HSA-113418	4.613538e-01	0.336	0	0
Negative regulation of FGFR3 signaling	R-HSA-5654732	4.613538e-01	0.336	0	0
Protein hydroxylation	R-HSA-9629569	4.731870e-01	0.325	0	0
Rab regulation of trafficking	R-HSA-9007101	4.762146e-01	0.322	0	0
Regulation of gene expression in beta cells	R-HSA-210745	4.833923e-01	0.316	0	0
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	4.833923e-01	0.316	0	0
Negative regulation of FGFR4 signaling	R-HSA-5654733	4.833923e-01	0.316	0	0
Signaling by CSF3 (G-CSF)	R-HSA-9674555	4.833923e-01	0.316	0	0
Polymerase switching	R-HSA-69091	4.887659e-01	0.311	0	0
Leading Strand Synthesis	R-HSA-69109	4.887659e-01	0.311	0	0
RUNX3 regulates NOTCH signaling	R-HSA-8941856	4.887659e-01	0.311	0	0
Repression of WNT target genes	R-HSA-4641265	4.887659e-01	0.311	0	0
Regulation of FOXO transcriptional activity by acetylation	R-HSA-9617629	4.887659e-01	0.311	0	0
MET promotes cell motility	R-HSA-8875878	4.905476e-01	0.309	0	0
SLC-mediated transport of inorganic anions	R-HSA-9958790	4.905476e-01	0.309	0	0
RAB GEFs exchange GTP for GDP on RABs	R-HSA-8876198	4.977396e-01	0.303	0	0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	R-HSA-166058	4.986226e-01	0.302	0	0
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	4.986226e-01	0.302	0	0
Regulation of MITF-M-dependent genes involved in apoptosis	R-HSA-9824594	4.988709e-01	0.302	0	0
ERK/MAPK targets	R-HSA-198753	4.988709e-01	0.302	0	0
Acetylcholine Neurotransmitter Release Cycle	R-HSA-264642	4.988709e-01	0.302	0	0
Epigenetic regulation by WDR5-containing histone modifying complexes	R-HSA-9917777	4.992228e-01	0.302	0	0
Hemostasis	R-HSA-109582	4.992960e-01	0.302	0	0
GABA synthesis, release, reuptake and degradation	R-HSA-888590	5.050614e-01	0.297	0	0
Interleukin-37 signaling	R-HSA-9008059	5.050614e-01	0.297	0	0
RAS processing	R-HSA-9648002	5.096390e-01	0.293	0	0
G2 Phase	R-HSA-68911	5.126233e-01	0.290	0	0
NTRK2 activates RAC1	R-HSA-9032759	5.126233e-01	0.290	0	0
Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA)	R-HSA-5619067	5.126233e-01	0.290	0	0
Defective SLC1A3 causes episodic ataxia 6 (EA6)	R-HSA-5619062	5.126233e-01	0.290	0	0
PTK6 Down-Regulation	R-HSA-8849472	5.126233e-01	0.290	0	0
Activation of AKT2	R-HSA-165158	5.126233e-01	0.290	0	0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	R-HSA-3134963	5.126233e-01	0.290	0	0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	R-HSA-3134973	5.126233e-01	0.290	0	0
Toxicity of botulinum toxin type G (botG)	R-HSA-5250989	5.126233e-01	0.290	0	0
Suppression of autophagy	R-HSA-9636569	5.126233e-01	0.290	0	0
Muscarinic acetylcholine receptors	R-HSA-390648	5.126233e-01	0.290	0	0
Reelin signalling pathway	R-HSA-8866376	5.126233e-01	0.290	0	0
NrCAM interactions	R-HSA-447038	5.126233e-01	0.290	0	0
Toxicity of botulinum toxin type C (botC)	R-HSA-5250971	5.126233e-01	0.290	0	0
PTK6 Regulates Proteins Involved in RNA Processing	R-HSA-8849468	5.126233e-01	0.290	0	0
Assembly of Viral Components at the Budding Site	R-HSA-168316	5.126233e-01	0.290	0	0
Fcgamma receptor (FCGR) dependent phagocytosis	R-HSA-2029480	5.133862e-01	0.290	0	0
Respiratory Syncytial Virus Infection Pathway	R-HSA-9820952	5.145232e-01	0.289	0	0
Formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	5.165005e-01	0.287	0	0
CD28 dependent Vav1 pathway	R-HSA-389359	5.207434e-01	0.283	0	0
Formation of axial mesoderm	R-HSA-9796292	5.207434e-01	0.283	0	0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	R-HSA-9029558	5.207434e-01	0.283	0	0
Molecules associated with elastic fibres	R-HSA-2129379	5.263167e-01	0.279	0	0
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	5.318069e-01	0.274	0	0
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	5.318069e-01	0.274	0	0
Developmental Lineage of Pancreatic Ductal Cells	R-HSA-9925563	5.338918e-01	0.273	0	0
Transmission across Chemical Synapses	R-HSA-112315	5.374039e-01	0.270	0	0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	R-HSA-381426	5.413815e-01	0.266	0	0
Signaling by Nuclear Receptors	R-HSA-9006931	5.423278e-01	0.266	0	0
Gastrulation	R-HSA-9758941	5.465229e-01	0.262	0	0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	R-HSA-9857377	5.482320e-01	0.261	0	0
FGFR2 alternative splicing	R-HSA-6803529	5.482320e-01	0.261	0	0
RNA Polymerase III Transcription Initiation From Type 3 Promoter	R-HSA-76071	5.482320e-01	0.261	0	0
Dopamine Neurotransmitter Release Cycle	R-HSA-212676	5.482320e-01	0.261	0	0
Regulation of endogenous retroelements by KRAB-ZFP proteins	R-HSA-9843940	5.483333e-01	0.261	0	0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	R-HSA-9856530	5.491047e-01	0.260	0	0
Class I MHC mediated antigen processing & presentation	R-HSA-983169	5.510302e-01	0.259	0	0
Retrograde neurotrophin signalling	R-HSA-177504	5.513515e-01	0.259	0	0
ERBB2 Activates PTK6 Signaling	R-HSA-8847993	5.513515e-01	0.259	0	0
Regulation of CDH1 mRNA translation by microRNAs	R-HSA-9764562	5.513515e-01	0.259	0	0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	R-HSA-77310	5.513515e-01	0.259	0	0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA	R-HSA-77350	5.513515e-01	0.259	0	0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA	R-HSA-77348	5.513515e-01	0.259	0	0
Malate-aspartate shuttle	R-HSA-9856872	5.513515e-01	0.259	0	0
Signal regulatory protein family interactions	R-HSA-391160	5.513515e-01	0.259	0	0
Acyl chain remodeling of CL	R-HSA-1482798	5.513515e-01	0.259	0	0
Zinc transporters	R-HSA-435354	5.513515e-01	0.259	0	0
Signaling by Overexpressed Wild-Type EGFR in Cancer	R-HSA-5638302	5.601922e-01	0.252	0	0
CDC6 association with the ORC:origin complex	R-HSA-68689	5.601922e-01	0.252	0	0
Inhibition of Signaling by Overexpressed EGFR	R-HSA-5638303	5.601922e-01	0.252	0	0
Phosphorylation of Emi1	R-HSA-176417	5.601922e-01	0.252	1	1
PTK6 Regulates Cell Cycle	R-HSA-8849470	5.601922e-01	0.252	0	0
Loss of MECP2 binding ability to the NCoR/SMRT complex	R-HSA-9022537	5.601922e-01	0.252	0	0
CLEC7A/inflammasome pathway	R-HSA-5660668	5.601922e-01	0.252	0	0
PKA-mediated phosphorylation of key metabolic factors	R-HSA-163358	5.601922e-01	0.252	0	0
PDE3B signalling	R-HSA-165160	5.601922e-01	0.252	0	0
PKB-mediated events	R-HSA-109703	5.601922e-01	0.252	0	0
Noncanonical activation of NOTCH3	R-HSA-9017802	5.601922e-01	0.252	0	0
Sodium-coupled phosphate cotransporters	R-HSA-427652	5.601922e-01	0.252	0	0
Orexin and neuropeptides FF and QRFP bind to their respective receptors	R-HSA-389397	5.601922e-01	0.252	0	0
Toxicity of botulinum toxin type E (botE)	R-HSA-5250992	5.601922e-01	0.252	0	0
TRAIL signaling	R-HSA-75158	5.601922e-01	0.252	0	0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	R-HSA-9615017	5.650168e-01	0.248	0	0
G-protein beta:gamma signalling	R-HSA-397795	5.674344e-01	0.246	0	0
Negative regulation of FGFR1 signaling	R-HSA-5654726	5.674344e-01	0.246	0	0
RNA Pol II CTD phosphorylation and interaction with CE	R-HSA-77075	5.718132e-01	0.243	0	0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	R-HSA-167160	5.718132e-01	0.243	0	0
The role of Nef in HIV-1 replication and disease pathogenesis	R-HSA-164952	5.718132e-01	0.243	0	0
G beta:gamma signalling through PI3Kgamma	R-HSA-392451	5.718132e-01	0.243	0	0
C-type lectin receptors (CLRs)	R-HSA-5621481	5.765166e-01	0.239	0	0
Synthesis of PIPs at the plasma membrane	R-HSA-1660499	5.779383e-01	0.238	0	0
Transcriptional regulation of granulopoiesis	R-HSA-9616222	5.779383e-01	0.238	0	0
Neurexins and neuroligins	R-HSA-6794361	5.798632e-01	0.237	0	0
Formation of the anterior neural plate	R-HSA-9823739	5.805531e-01	0.236	0	0
Interleukin-4 and Interleukin-13 signaling	R-HSA-6785807	5.860556e-01	0.232	0	0
Effects of PIP2 hydrolysis	R-HSA-114508	5.872340e-01	0.231	0	0
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	5.888715e-01	0.230	0	0
TRAF6 mediated NF-kB activation	R-HSA-933542	5.946137e-01	0.226	0	0
Norepinephrine Neurotransmitter Release Cycle	R-HSA-181430	5.946137e-01	0.226	0	0
CD209 (DC-SIGN) signaling	R-HSA-5621575	5.946137e-01	0.226	0	0
Selenoamino acid metabolism	R-HSA-2408522	5.946513e-01	0.226	0	0
Late SARS-CoV-2 Infection Events	R-HSA-9772573	5.999366e-01	0.222	0	0
Defective pyroptosis	R-HSA-9710421	6.000962e-01	0.222	0	0
Signaling by FGFR4	R-HSA-5654743	6.000962e-01	0.222	0	0
Signaling by LTK in cancer	R-HSA-9842640	6.031208e-01	0.220	0	0
STAT5 Activation	R-HSA-9645135	6.031208e-01	0.220	0	0
RUNX3 regulates YAP1-mediated transcription	R-HSA-8951671	6.031208e-01	0.220	0	0
Autointegration results in viral DNA circles	R-HSA-177539	6.031208e-01	0.220	0	0
E2F-enabled inhibition of pre-replication complex formation	R-HSA-113507	6.031208e-01	0.220	0	0
Neurofascin interactions	R-HSA-447043	6.031208e-01	0.220	0	0
Integration of viral DNA into host genomic DNA	R-HSA-175567	6.031208e-01	0.220	0	0
Abacavir transmembrane transport	R-HSA-2161517	6.031208e-01	0.220	0	0
NADPH regeneration	R-HSA-389542	6.031208e-01	0.220	0	0
HDL clearance	R-HSA-8964011	6.031208e-01	0.220	0	0
Nef and signal transduction	R-HSA-164944	6.031208e-01	0.220	0	0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	R-HSA-983170	6.064937e-01	0.217	0	0
Negative regulation of FGFR2 signaling	R-HSA-5654727	6.064937e-01	0.217	0	0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	R-HSA-399955	6.083309e-01	0.216	0	0
Phase 4 - resting membrane potential	R-HSA-5576886	6.083309e-01	0.216	0	0
Atorvastatin ADME	R-HSA-9754706	6.083309e-01	0.216	0	0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	R-HSA-210744	6.083309e-01	0.216	0	0
Interleukin-7 signaling	R-HSA-1266695	6.166087e-01	0.210	0	0
Acyl chain remodelling of PS	R-HSA-1482801	6.166087e-01	0.210	0	0
Netrin-1 signaling	R-HSA-373752	6.170222e-01	0.210	0	0
Platelet Aggregation (Plug Formation)	R-HSA-76009	6.335181e-01	0.198	0	0
Signaling by FGFR3	R-HSA-5654741	6.335181e-01	0.198	0	0
GRB2 events in ERBB2 signaling	R-HSA-1963640	6.346848e-01	0.197	0	0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	R-HSA-77346	6.346848e-01	0.197	0	0
Synthesis of PG	R-HSA-1483148	6.346848e-01	0.197	0	0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	R-HSA-2892247	6.346848e-01	0.197	0	0
Myogenesis	R-HSA-525793	6.377808e-01	0.195	0	0
Signaling by FLT3 fusion proteins	R-HSA-9703465	6.377808e-01	0.195	0	0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway	R-HSA-110373	6.377808e-01	0.195	0	0
Caspase activation via extrinsic apoptotic signalling pathway	R-HSA-5357769	6.377808e-01	0.195	0	0
Synthesis of IP2, IP, and Ins in the cytosol	R-HSA-1855183	6.377808e-01	0.195	0	0
Synthesis of PIPs at the Golgi membrane	R-HSA-1660514	6.377808e-01	0.195	0	0
Signaling by FGFR1	R-HSA-5654736	6.414577e-01	0.193	0	0
NRAGE signals death through JNK	R-HSA-193648	6.414577e-01	0.193	0	0
MET activates PI3K/AKT signaling	R-HSA-8851907	6.418616e-01	0.193	0	0
RUNX3 regulates WNT signaling	R-HSA-8951430	6.418616e-01	0.193	0	0
Binding of TCF/LEF:CTNNB1 to target gene promoters	R-HSA-4411364	6.418616e-01	0.193	0	0
Pre-NOTCH Processing in the Endoplasmic Reticulum	R-HSA-1912399	6.418616e-01	0.193	0	0
DAG1 core M1 glycosylations	R-HSA-8932506	6.418616e-01	0.193	0	0
SHOC2 M1731 mutant abolishes MRAS complex function	R-HSA-9726840	6.418616e-01	0.193	0	0
NOSTRIN mediated eNOS trafficking	R-HSA-203641	6.418616e-01	0.193	0	0
Insulin effects increased synthesis of Xylulose-5-Phosphate	R-HSA-163754	6.418616e-01	0.193	0	0
Activation of PUMA and translocation to mitochondria	R-HSA-139915	6.418616e-01	0.193	0	0
VLDL clearance	R-HSA-8964046	6.418616e-01	0.193	0	0
Displacement of DNA glycosylase by APEX1	R-HSA-110357	6.418616e-01	0.193	0	0
TGFBR3 regulates TGF-beta signaling	R-HSA-9839389	6.418616e-01	0.193	0	0
G1/S-Specific Transcription	R-HSA-69205	6.433190e-01	0.192	0	0
RET signaling	R-HSA-8853659	6.433190e-01	0.192	0	0
Cell recruitment (pro-inflammatory response)	R-HSA-9664424	6.495713e-01	0.187	0	0
Purinergic signaling in leishmaniasis infection	R-HSA-9660826	6.495713e-01	0.187	0	0
Post-translational protein modification	R-HSA-597592	6.516186e-01	0.186	0	0
Circadian clock	R-HSA-9909396	6.558841e-01	0.183	0	0
G alpha (12/13) signalling events	R-HSA-416482	6.561785e-01	0.183	0	0
Tat-mediated HIV elongation arrest and recovery	R-HSA-167243	6.581197e-01	0.182	0	0
Pausing and recovery of Tat-mediated HIV elongation	R-HSA-167238	6.581197e-01	0.182	0	0
Insulin processing	R-HSA-264876	6.581197e-01	0.182	0	0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	R-HSA-5358606	6.596281e-01	0.181	0	0
Elevation of cytosolic Ca2+ levels	R-HSA-139853	6.596281e-01	0.181	0	0
Synthesis of PIPs at the late endosome membrane	R-HSA-1660517	6.596281e-01	0.181	0	0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	R-HSA-164938	6.596281e-01	0.181	0	0
Uptake and function of anthrax toxins	R-HSA-5210891	6.596281e-01	0.181	0	0
Toll-like Receptor Cascades	R-HSA-168898	6.617360e-01	0.179	0	0
Activated NTRK2 signals through FYN	R-HSA-9032500	6.768227e-01	0.170	0	0
ALKBH3 mediated reversal of alkylation damage	R-HSA-112126	6.768227e-01	0.170	0	0
phospho-PLA2 pathway	R-HSA-111995	6.768227e-01	0.170	0	0
EGFR interacts with phospholipase C-gamma	R-HSA-212718	6.768227e-01	0.170	0	0
DAG1 core M2 glycosylations	R-HSA-8932504	6.768227e-01	0.170	0	0
MET receptor recycling	R-HSA-8875656	6.768227e-01	0.170	0	0
Activated NTRK2 signals through PI3K	R-HSA-9028335	6.768227e-01	0.170	0	0
Signaling by MRAS-complex mutants	R-HSA-9660537	6.768227e-01	0.170	0	0
Gain-of-function MRAS complexes activate RAF signaling	R-HSA-9726842	6.768227e-01	0.170	0	0
Toxicity of botulinum toxin type B (botB)	R-HSA-5250958	6.768227e-01	0.170	0	0
TGFBR3 PTM regulation	R-HSA-9839383	6.768227e-01	0.170	0	0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors	R-HSA-8866904	6.768227e-01	0.170	0	0
ATF4 activates genes in response to endoplasmic reticulum stress	R-HSA-380994	6.776209e-01	0.169	0	0
HIV elongation arrest and recovery	R-HSA-167287	6.776209e-01	0.169	0	0
Pausing and recovery of HIV elongation	R-HSA-167290	6.776209e-01	0.169	0	0
Insulin receptor recycling	R-HSA-77387	6.776209e-01	0.169	0	0
Phase 0 - rapid depolarisation	R-HSA-5576892	6.776209e-01	0.169	0	0
RUNX2 regulates osteoblast differentiation	R-HSA-8940973	6.776209e-01	0.169	0	0
Elastic fibre formation	R-HSA-1566948	6.778015e-01	0.169	0	0
Gluconeogenesis	R-HSA-70263	6.803120e-01	0.167	0	0
Signaling by FGFR2	R-HSA-5654738	6.806419e-01	0.167	0	0
PCNA-Dependent Long Patch Base Excision Repair	R-HSA-5651801	6.831849e-01	0.165	0	0
Cytosolic iron-sulfur cluster assembly	R-HSA-2564830	6.831849e-01	0.165	0	0
RNA Polymerase III Transcription Termination	R-HSA-73980	6.831849e-01	0.165	0	0
Polo-like kinase mediated events	R-HSA-156711	6.831849e-01	0.165	1	1
Trafficking of GluR2-containing AMPA receptors	R-HSA-416993	6.831849e-01	0.165	0	0
Signaling by cytosolic FGFR1 fusion mutants	R-HSA-1839117	6.831849e-01	0.165	0	0
Apoptotic factor-mediated response	R-HSA-111471	6.831849e-01	0.165	0	0
Regulation of beta-cell development	R-HSA-186712	6.839124e-01	0.165	0	0
Formation of HIV-1 elongation complex containing HIV-1 Tat	R-HSA-167200	6.941461e-01	0.159	0	0
Expression of BMAL (ARNTL), CLOCK, and NPAS2	R-HSA-9931509	6.941461e-01	0.159	0	0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	R-HSA-9725554	6.941461e-01	0.159	0	0
Respiratory syncytial virus (RSV) genome replication, transcription and translation	R-HSA-9820965	6.941461e-01	0.159	0	0
mRNA Capping	R-HSA-72086	6.962856e-01	0.157	0	0
Platelet calcium homeostasis	R-HSA-418360	6.962856e-01	0.157	0	0
Regulation of CDH11 Expression and Function	R-HSA-9759475	6.962856e-01	0.157	0	0
Germ layer formation at gastrulation	R-HSA-9754189	7.053882e-01	0.152	0	0
Other interleukin signaling	R-HSA-449836	7.053882e-01	0.152	0	0
Estrogen-stimulated signaling through PRKCZ	R-HSA-9634635	7.083729e-01	0.150	0	0
WNT mediated activation of DVL	R-HSA-201688	7.083729e-01	0.150	0	0
MAPK1 (ERK2) activation	R-HSA-112411	7.083729e-01	0.150	0	0
Calcineurin activates NFAT	R-HSA-2025928	7.083729e-01	0.150	0	0
5-Phosphoribose 1-diphosphate biosynthesis	R-HSA-73843	7.083729e-01	0.150	0	0
Activation of the AP-1 family of transcription factors	R-HSA-450341	7.083729e-01	0.150	0	0
Activation of RAC1 downstream of NMDARs	R-HSA-9619229	7.083729e-01	0.150	0	0
Activation of the TFAP2 (AP-2) family of transcription factors	R-HSA-8866907	7.083729e-01	0.150	0	0
Regulation of NPAS4 gene transcription	R-HSA-9768777	7.083729e-01	0.150	0	0
Regulation of CDH11 gene transcription	R-HSA-9762293	7.083729e-01	0.150	0	0
Regulated proteolysis of p75NTR	R-HSA-193692	7.083729e-01	0.150	0	0
Toxicity of botulinum toxin type A (botA)	R-HSA-5250968	7.083729e-01	0.150	0	0
Formation of HIV elongation complex in the absence of HIV Tat	R-HSA-167152	7.098896e-01	0.149	0	0
HIV Transcription Elongation	R-HSA-167169	7.098896e-01	0.149	0	0
Tat-mediated elongation of the HIV-1 transcript	R-HSA-167246	7.098896e-01	0.149	0	0
Glycogen metabolism	R-HSA-8982491	7.098896e-01	0.149	0	0
Extra-nuclear estrogen signaling	R-HSA-9009391	7.117662e-01	0.148	0	0
Interconversion of nucleotide di- and triphosphates	R-HSA-499943	7.124799e-01	0.147	0	0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression	R-HSA-9933387	7.141196e-01	0.146	0	0
Plasma lipoprotein assembly, remodeling, and clearance	R-HSA-174824	7.183947e-01	0.144	0	0
PI Metabolism	R-HSA-1483255	7.217638e-01	0.142	0	0
NCAM signaling for neurite out-growth	R-HSA-375165	7.229430e-01	0.141	0	0
Signaling by PDGF	R-HSA-186797	7.229430e-01	0.141	0	0
Resolution of Abasic Sites (AP sites)	R-HSA-73933	7.250330e-01	0.140	0	0
Ion channel transport	R-HSA-983712	7.254624e-01	0.139	0	0
Regulation of PD-L1(CD274) translation	R-HSA-9909620	7.262778e-01	0.139	0	0
Formation of definitive endoderm	R-HSA-9823730	7.262778e-01	0.139	0	0
Downstream signal transduction	R-HSA-186763	7.311326e-01	0.136	0	0
Pre-NOTCH Expression and Processing	R-HSA-1912422	7.345488e-01	0.134	0	0
MAPK3 (ERK1) activation	R-HSA-110056	7.368447e-01	0.133	0	0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2	R-HSA-5140745	7.368447e-01	0.133	0	0
Maturation of spike protein	R-HSA-9683686	7.368447e-01	0.133	0	0
Metal sequestration by antimicrobial proteins	R-HSA-6799990	7.368447e-01	0.133	0	0
Regulation of the apoptosome activity	R-HSA-9627069	7.368447e-01	0.133	0	0
Formation of apoptosome	R-HSA-111458	7.368447e-01	0.133	0	0
Adipogenesis	R-HSA-9843745	7.409157e-01	0.130	0	0
Opioid Signalling	R-HSA-111885	7.410726e-01	0.130	0	0
Lagging Strand Synthesis	R-HSA-69186	7.458984e-01	0.127	0	0
Basigin interactions	R-HSA-210991	7.458984e-01	0.127	0	0
Maternal to zygotic transition (MZT)	R-HSA-9816359	7.463513e-01	0.127	0	0
RSV-host interactions	R-HSA-9833110	7.503812e-01	0.125	0	0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	R-HSA-381676	7.535352e-01	0.123	0	0
DAG1 core M3 glycosylations	R-HSA-8932505	7.625382e-01	0.118	0	0
Signaling by APC mutants	R-HSA-4839744	7.625382e-01	0.118	0	0
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	7.625382e-01	0.118	0	0
Truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	7.625382e-01	0.118	0	0
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	7.625382e-01	0.118	0	0
vRNA Synthesis	R-HSA-192814	7.625382e-01	0.118	0	0
Bicarbonate transporters	R-HSA-425381	7.625382e-01	0.118	0	0
SARS-CoV-2 modulates autophagy	R-HSA-9754560	7.625382e-01	0.118	0	0
CD163 mediating an anti-inflammatory response	R-HSA-9662834	7.625382e-01	0.118	0	0
Dissolution of Fibrin Clot	R-HSA-75205	7.625382e-01	0.118	0	0
Regulation of Expression and Function of Type II Classical Cadherins	R-HSA-9764260	7.627520e-01	0.118	0	0
Synthesis of IP3 and IP4 in the cytosol	R-HSA-1855204	7.627520e-01	0.118	0	0
Mitochondrial calcium ion transport	R-HSA-8949215	7.642987e-01	0.117	0	0
Serine metabolism	R-HSA-977347	7.642987e-01	0.117	0	0
Ribavirin ADME	R-HSA-9755088	7.642987e-01	0.117	0	0
Signaling by SCF-KIT	R-HSA-1433557	7.669073e-01	0.115	0	0
Disorders of transmembrane transporters	R-HSA-5619115	7.701838e-01	0.113	0	0
Metabolism of proteins	R-HSA-392499	7.729162e-01	0.112	0	0
G alpha (z) signalling events	R-HSA-418597	7.731684e-01	0.112	0	0
FCERI mediated NF-kB activation	R-HSA-2871837	7.749811e-01	0.111	0	0
Regulation of IFNA/IFNB signaling	R-HSA-912694	7.815299e-01	0.107	0	0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants	R-HSA-9670439	7.815299e-01	0.107	0	0
RAF-independent MAPK1/3 activation	R-HSA-112409	7.815299e-01	0.107	0	0
Signaling by KIT in disease	R-HSA-9669938	7.815299e-01	0.107	0	0
WNT ligand biogenesis and trafficking	R-HSA-3238698	7.815299e-01	0.107	0	0
Neurotoxicity of clostridium toxins	R-HSA-168799	7.815299e-01	0.107	0	0
LDL clearance	R-HSA-8964038	7.815299e-01	0.107	0	0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	R-HSA-6803205	7.815299e-01	0.107	0	0
Signaling by FGFR	R-HSA-190236	7.852802e-01	0.105	0	0
Synthesis of diphthamide-EEF2	R-HSA-5358493	7.857245e-01	0.105	0	0
ERKs are inactivated	R-HSA-202670	7.857245e-01	0.105	0	0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters	R-HSA-9931512	7.857245e-01	0.105	0	0
Signaling by GSK3beta mutants	R-HSA-5339716	7.857245e-01	0.105	0	0
Endosomal/Vacuolar pathway	R-HSA-1236977	7.857245e-01	0.105	0	0
POLB-Dependent Long Patch Base Excision Repair	R-HSA-110362	7.857245e-01	0.105	0	0
Signaling by AXIN mutants	R-HSA-4839735	7.857245e-01	0.105	0	0
Signaling by AMER1 mutants	R-HSA-4839748	7.857245e-01	0.105	0	0
Sema4D mediated inhibition of cell attachment and migration	R-HSA-416550	7.857245e-01	0.105	0	0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis	R-HSA-9623433	7.857245e-01	0.105	0	0
Reduction of cytosolic Ca++ levels	R-HSA-418359	7.857245e-01	0.105	0	0
APOBEC3G mediated resistance to HIV-1 infection	R-HSA-180689	7.857245e-01	0.105	0	0
Developmental Lineage of Mammary Gland Alveolar Cells	R-HSA-9927426	7.912831e-01	0.102	0	0
NPAS4 regulates expression of target genes	R-HSA-9768919	7.912831e-01	0.102	0	0
Synthesis of PA	R-HSA-1483166	7.955329e-01	0.099	0	0
Regulation of PTEN mRNA translation	R-HSA-8943723	7.976448e-01	0.098	0	0
Pre-NOTCH Transcription and Translation	R-HSA-1912408	8.035655e-01	0.095	0	0
Condensation of Prophase Chromosomes	R-HSA-2299718	8.036218e-01	0.095	1	1
Signaling by TGFBR3	R-HSA-9839373	8.036218e-01	0.095	0	0
Transferrin endocytosis and recycling	R-HSA-917977	8.044435e-01	0.095	0	0
Amyloid fiber formation	R-HSA-977225	8.060837e-01	0.094	0	0
Signaling by CTNNB1 phospho-site mutants	R-HSA-4839743	8.066481e-01	0.093	0	0
CTNNB1 S45 mutants aren't phosphorylated	R-HSA-5358751	8.066481e-01	0.093	0	0
CTNNB1 S33 mutants aren't phosphorylated	R-HSA-5358747	8.066481e-01	0.093	0	0
CTNNB1 T41 mutants aren't phosphorylated	R-HSA-5358752	8.066481e-01	0.093	0	0
CTNNB1 S37 mutants aren't phosphorylated	R-HSA-5358749	8.066481e-01	0.093	0	0
Beta oxidation of myristoyl-CoA to lauroyl-CoA	R-HSA-77285	8.066481e-01	0.093	0	0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA	R-HSA-77305	8.066481e-01	0.093	0	0
GRB2 events in EGFR signaling	R-HSA-179812	8.066481e-01	0.093	0	0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	R-HSA-9027276	8.066481e-01	0.093	0	0
Reversal of alkylation damage by DNA dioxygenases	R-HSA-73943	8.066481e-01	0.093	0	0
Trafficking and processing of endosomal TLR	R-HSA-1679131	8.066481e-01	0.093	0	0
Advanced glycosylation endproduct receptor signaling	R-HSA-879415	8.066481e-01	0.093	0	0
Regulation of IFNG signaling	R-HSA-877312	8.066481e-01	0.093	0	0
MET activates RAS signaling	R-HSA-8851805	8.066481e-01	0.093	0	0
Signaling by LTK	R-HSA-9842663	8.066481e-01	0.093	0	0
OAS antiviral response	R-HSA-8983711	8.066481e-01	0.093	0	0
Negative regulation of the PI3K/AKT network	R-HSA-199418	8.086733e-01	0.092	0	0
Translocation of ZAP-70 to Immunological synapse	R-HSA-202430	8.126970e-01	0.090	0	0
ADP signalling through P2Y purinoceptor 1	R-HSA-418592	8.126970e-01	0.090	0	0
Complex III assembly	R-HSA-9865881	8.126970e-01	0.090	0	0
Replacement of protamines by nucleosomes in the male pronucleus	R-HSA-9821993	8.126970e-01	0.090	0	0
Extension of Telomeres	R-HSA-180786	8.161287e-01	0.088	0	0
Peroxisomal protein import	R-HSA-9033241	8.161287e-01	0.088	0	0
Assembly of collagen fibrils and other multimeric structures	R-HSA-2022090	8.161287e-01	0.088	0	0
GPVI-mediated activation cascade	R-HSA-114604	8.168983e-01	0.088	0	0
RUNX2 regulates bone development	R-HSA-8941326	8.168983e-01	0.088	0	0
Regulation of actin dynamics for phagocytic cup formation	R-HSA-2029482	8.222638e-01	0.085	0	0
CREB1 phosphorylation through the activation of Adenylate Cyclase	R-HSA-442720	8.255296e-01	0.083	0	0
Processing of SMDT1	R-HSA-8949664	8.255296e-01	0.083	0	0
Platelet Adhesion to exposed collagen	R-HSA-75892	8.255296e-01	0.083	0	0
Metabolism of polyamines	R-HSA-351202	8.257847e-01	0.083	0	0
Polymerase switching on the C-strand of the telomere	R-HSA-174411	8.267405e-01	0.083	0	0
TGFBR3 expression	R-HSA-9839394	8.267405e-01	0.083	0	0
HDMs demethylate histones	R-HSA-3214842	8.267405e-01	0.083	0	0
Synthesis of PIPs at the early endosome membrane	R-HSA-1660516	8.267405e-01	0.083	0	0
Mitochondrial protein degradation	R-HSA-9837999	8.354720e-01	0.078	0	0
Constitutive Signaling by Aberrant PI3K in Cancer	R-HSA-2219530	8.354720e-01	0.078	0	0
Protein-protein interactions at synapses	R-HSA-6794362	8.393528e-01	0.076	0	0
Activation of anterior HOX genes in hindbrain development during early embryogenesis	R-HSA-5617472	8.397772e-01	0.076	0	0
Activation of HOX genes during differentiation	R-HSA-5619507	8.397772e-01	0.076	0	0
Metabolism of nitric oxide: NOS3 activation and regulation	R-HSA-202131	8.397907e-01	0.076	0	0
TRP channels	R-HSA-3295583	8.398285e-01	0.076	0	0
CRMPs in Sema3A signaling	R-HSA-399956	8.425683e-01	0.074	0	0
Removal of the Flap Intermediate	R-HSA-69166	8.425683e-01	0.074	0	0
YAP1- and WWTR1 (TAZ)-stimulated gene expression	R-HSA-2032785	8.425683e-01	0.074	0	0
Hydrolysis of LPC	R-HSA-1483115	8.425683e-01	0.074	0	0
CLEC7A (Dectin-1) induces NFAT activation	R-HSA-5607763	8.425683e-01	0.074	0	0
Signaling by FGFR4 in disease	R-HSA-5655291	8.425683e-01	0.074	0	0
Physiological factors	R-HSA-5578768	8.425683e-01	0.074	0	0
Respiratory syncytial virus genome transcription	R-HSA-9828642	8.425683e-01	0.074	0	0
HDL assembly	R-HSA-8963896	8.425683e-01	0.074	0	0
P2Y receptors	R-HSA-417957	8.425683e-01	0.074	0	0
Heme signaling	R-HSA-9707616	8.438616e-01	0.074	0	0
Mitochondrial protein import	R-HSA-1268020	8.438616e-01	0.074	0	0
Processive synthesis on the C-strand of the telomere	R-HSA-174414	8.520138e-01	0.070	0	0
Phosphorylation of CD3 and TCR zeta chains	R-HSA-202427	8.520138e-01	0.070	0	0
Disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	8.520138e-01	0.070	0	0
Signaling by NTRK2 (TRKB)	R-HSA-9006115	8.520138e-01	0.070	0	0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	R-HSA-6803204	8.520138e-01	0.070	0	0
Erythropoietin activates RAS	R-HSA-9027284	8.579439e-01	0.067	0	0
Beta-catenin phosphorylation cascade	R-HSA-196299	8.579439e-01	0.067	0	0
SHC1 events in EGFR signaling	R-HSA-180336	8.579439e-01	0.067	0	0
RNA Polymerase III Chain Elongation	R-HSA-73780	8.579439e-01	0.067	0	0
Processive synthesis on the lagging strand	R-HSA-69183	8.579439e-01	0.067	0	0
DNA Damage Reversal	R-HSA-73942	8.579439e-01	0.067	0	0
Protein repair	R-HSA-5676934	8.579439e-01	0.067	0	0
Beta oxidation of butanoyl-CoA to acetyl-CoA	R-HSA-77352	8.579439e-01	0.067	0	0
Inhibition of DNA recombination at telomere	R-HSA-9670095	8.601646e-01	0.065	0	0
Diseases of Immune System	R-HSA-5260271	8.601646e-01	0.065	0	0
Diseases associated with the TLR signaling cascade	R-HSA-5602358	8.601646e-01	0.065	0	0
Mitochondrial biogenesis	R-HSA-1592230	8.627872e-01	0.064	0	0
RNA Polymerase I Promoter Escape	R-HSA-73772	8.629238e-01	0.064	0	0
Transcriptional Regulation by NPAS4	R-HSA-9634815	8.629238e-01	0.064	0	0
Telomere Maintenance	R-HSA-157579	8.631588e-01	0.064	0	0
Telomere Extension By Telomerase	R-HSA-171319	8.633477e-01	0.064	0	0
Prednisone ADME	R-HSA-9757110	8.633477e-01	0.064	0	0
Neuronal System	R-HSA-112316	8.663478e-01	0.062	0	0
NR1H2 and NR1H3-mediated signaling	R-HSA-9024446	8.672615e-01	0.062	0	0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	R-HSA-5625886	8.694721e-01	0.061	0	0
Entry of Influenza Virion into Host Cell via Endocytosis	R-HSA-168275	8.718187e-01	0.060	0	0
WNT5:FZD7-mediated leishmania damping	R-HSA-9673324	8.718187e-01	0.060	0	0
Killing mechanisms	R-HSA-9664420	8.718187e-01	0.060	0	0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism	R-HSA-9634600	8.718187e-01	0.060	0	0
Activation of SMO	R-HSA-5635838	8.718187e-01	0.060	0	0
Fructose catabolism	R-HSA-70350	8.718187e-01	0.060	0	0
Receptor-type tyrosine-protein phosphatases	R-HSA-388844	8.718187e-01	0.060	0	0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	R-HSA-6804116	8.718187e-01	0.060	0	0
Attachment and Entry	R-HSA-9678110	8.718187e-01	0.060	0	0
Virus Assembly and Release	R-HSA-168268	8.718187e-01	0.060	0	0
DNA methylation	R-HSA-5334118	8.738804e-01	0.059	0	0
DARPP-32 events	R-HSA-180024	8.738804e-01	0.059	0	0
Signaling by Erythropoietin	R-HSA-9006335	8.738804e-01	0.059	0	0
Integrin cell surface interactions	R-HSA-216083	8.741316e-01	0.058	0	0
Telomere C-strand (Lagging Strand) Synthesis	R-HSA-174417	8.782281e-01	0.056	0	0
Scavenging by Class A Receptors	R-HSA-3000480	8.782281e-01	0.056	0	0
Signaling by FGFR1 in disease	R-HSA-5655302	8.782281e-01	0.056	0	0
DAP12 signaling	R-HSA-2424491	8.836601e-01	0.054	0	0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	R-HSA-1474151	8.836601e-01	0.054	0	0
G beta:gamma signalling through CDC42	R-HSA-8964616	8.843390e-01	0.053	0	0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex	R-HSA-9931521	8.843390e-01	0.053	0	0
TRAF3-dependent IRF activation pathway	R-HSA-918233	8.843390e-01	0.053	0	0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	R-HSA-77288	8.843390e-01	0.053	0	0
STAT5 activation downstream of FLT3 ITD mutants	R-HSA-9702518	8.843390e-01	0.053	0	0
Acetylcholine regulates insulin secretion	R-HSA-399997	8.843390e-01	0.053	0	0
Biosynthesis of maresin-like SPMs	R-HSA-9027307	8.843390e-01	0.053	0	0
Coenzyme A biosynthesis	R-HSA-196783	8.843390e-01	0.053	0	0
Cytosolic tRNA aminoacylation	R-HSA-379716	8.864580e-01	0.052	0	0
Cardiac conduction	R-HSA-5576891	8.869343e-01	0.052	0	0
Protein localization	R-HSA-9609507	8.919003e-01	0.050	0	0
Respiratory syncytial virus (RSV) attachment and entry	R-HSA-9820960	8.927335e-01	0.049	0	0
Cargo concentration in the ER	R-HSA-5694530	8.927335e-01	0.049	0	0
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	8.929760e-01	0.049	0	0
Removal of the Flap Intermediate from the C-strand	R-HSA-174437	8.956371e-01	0.048	0	0
Regulation of NPAS4 gene expression	R-HSA-9768759	8.956371e-01	0.048	0	0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se	R-HSA-2408550	8.956371e-01	0.048	0	0
Innate Immune System	R-HSA-168249	8.956391e-01	0.048	0	0
Cytoprotection by HMOX1	R-HSA-9707564	9.041571e-01	0.044	0	0
FOXO-mediated transcription of cell death genes	R-HSA-9614657	9.058321e-01	0.043	0	0
PKA activation	R-HSA-163615	9.058321e-01	0.043	0	0
PKA activation in glucagon signalling	R-HSA-164378	9.058321e-01	0.043	0	0
Platelet sensitization by LDL	R-HSA-432142	9.058321e-01	0.043	0	0
Nucleotide-like (purinergic) receptors	R-HSA-418038	9.058321e-01	0.043	0	0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	R-HSA-9029569	9.061837e-01	0.043	0	0
Early SARS-CoV-2 Infection Events	R-HSA-9772572	9.061837e-01	0.043	0	0
Disease	R-HSA-1643685	9.072013e-01	0.042	0	0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes	R-HSA-9818564	9.080114e-01	0.042	0	0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	R-HSA-9841922	9.080114e-01	0.042	0	0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes	R-HSA-9851695	9.080114e-01	0.042	0	0
FGFR1 mutant receptor activation	R-HSA-1839124	9.089376e-01	0.041	0	0
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	9.128639e-01	0.040	0	0
PI-3K cascade:FGFR3	R-HSA-5654710	9.150318e-01	0.039	0	0
Signaling by FGFR2 IIIa TM	R-HSA-8851708	9.150318e-01	0.039	0	0
mRNA decay by 3' to 5' exoribonuclease	R-HSA-429958	9.150318e-01	0.039	0	0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane	R-HSA-9768727	9.161516e-01	0.038	0	0
Glucagon signaling in metabolic regulation	R-HSA-163359	9.161516e-01	0.038	0	0
Acyl chain remodelling of PC	R-HSA-1482788	9.161516e-01	0.038	0	0
tRNA processing	R-HSA-72306	9.170963e-01	0.038	0	0
Diseases of carbohydrate metabolism	R-HSA-5663084	9.175565e-01	0.037	0	0
RAB geranylgeranylation	R-HSA-8873719	9.176459e-01	0.037	0	0
tRNA Aminoacylation	R-HSA-379724	9.176459e-01	0.037	0	0
Sphingolipid de novo biosynthesis	R-HSA-1660661	9.176459e-01	0.037	0	0
eNOS activation	R-HSA-203615	9.228259e-01	0.035	0	0
Signal amplification	R-HSA-392518	9.228259e-01	0.035	0	0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	R-HSA-110328	9.228259e-01	0.035	0	0
BMAL1:CLOCK,NPAS2 activates circadian expression	R-HSA-1368108	9.228259e-01	0.035	0	0
PI-3K cascade:FGFR4	R-HSA-5654720	9.233332e-01	0.035	0	0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	R-HSA-9609523	9.233332e-01	0.035	0	0
VxPx cargo-targeting to cilium	R-HSA-5620916	9.233332e-01	0.035	0	0
Creatine metabolism	R-HSA-71288	9.233332e-01	0.035	0	0
Acyl chain remodelling of PI	R-HSA-1482922	9.233332e-01	0.035	0	0
Signaling by NODAL	R-HSA-1181150	9.233332e-01	0.035	0	0
Common Pathway of Fibrin Clot Formation	R-HSA-140875	9.233332e-01	0.035	0	0
Stimuli-sensing channels	R-HSA-2672351	9.242600e-01	0.034	0	0
Metal ion SLC transporters	R-HSA-425410	9.261650e-01	0.033	0	0
Parasite infection	R-HSA-9664407	9.274586e-01	0.033	0	0
Leishmania phagocytosis	R-HSA-9664417	9.274586e-01	0.033	0	0
FCGR3A-mediated phagocytosis	R-HSA-9664422	9.274586e-01	0.033	0	0
Acyl chain remodelling of PE	R-HSA-1482839	9.289970e-01	0.032	0	0
Downstream signaling of activated FGFR1	R-HSA-5654687	9.289970e-01	0.032	0	0
Regulation of insulin secretion	R-HSA-422356	9.294895e-01	0.032	0	0
Matriglycan biosynthesis on DAG1	R-HSA-9939291	9.308240e-01	0.031	0	0
PKA-mediated phosphorylation of CREB	R-HSA-111931	9.308240e-01	0.031	0	0
Synthesis, secretion, and deacylation of Ghrelin	R-HSA-422085	9.308240e-01	0.031	0	0
Zygotic genome activation (ZGA)	R-HSA-9819196	9.308240e-01	0.031	0	0
Vitamin C (ascorbate) metabolism	R-HSA-196836	9.308240e-01	0.031	0	0
Acyl chain remodelling of PG	R-HSA-1482925	9.308240e-01	0.031	0	0
Activation of gene expression by SREBF (SREBP)	R-HSA-2426168	9.324954e-01	0.030	0	0
Infection with Mycobacterium tuberculosis	R-HSA-9635486	9.342831e-01	0.030	0	0
Triglyceride catabolism	R-HSA-163560	9.346994e-01	0.029	0	0
Formation of Fibrin Clot (Clotting Cascade)	R-HSA-140877	9.346994e-01	0.029	0	0
PI3K Cascade	R-HSA-109704	9.362654e-01	0.029	0	0
FOXO-mediated transcription of cell cycle genes	R-HSA-9617828	9.375832e-01	0.028	0	0
Metabolism of Angiotensinogen to Angiotensins	R-HSA-2022377	9.375832e-01	0.028	0	0
Attachment and Entry	R-HSA-9694614	9.375832e-01	0.028	0	0
Neurotransmitter release cycle	R-HSA-112310	9.393714e-01	0.027	0	0
Collagen chain trimerization	R-HSA-8948216	9.399657e-01	0.027	0	0
SLC transporter disorders	R-HSA-5619102	9.402377e-01	0.027	0	0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	R-HSA-6811558	9.406091e-01	0.027	0	0
PI-3K cascade:FGFR1	R-HSA-5654689	9.436824e-01	0.025	0	0
Fructose metabolism	R-HSA-5652084	9.436824e-01	0.025	0	0
Cellular hexose transport	R-HSA-189200	9.436824e-01	0.025	0	0
Transcriptional regulation of pluripotent stem cells	R-HSA-452723	9.448269e-01	0.025	0	0
tRNA modification in the nucleus and cytosol	R-HSA-6782315	9.448779e-01	0.025	0	0
Nicotinate metabolism	R-HSA-196807	9.485197e-01	0.023	0	0
ABC transporters in lipid homeostasis	R-HSA-1369062	9.491860e-01	0.023	0	0
Growth hormone receptor signaling	R-HSA-982772	9.491860e-01	0.023	0	0
Biosynthesis of maresins	R-HSA-9018682	9.491860e-01	0.023	0	0
Signaling by Insulin receptor	R-HSA-74752	9.492633e-01	0.023	0	0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	R-HSA-381771	9.493116e-01	0.023	0	0
Pentose phosphate pathway	R-HSA-71336	9.493116e-01	0.023	0	0
Mitochondrial tRNA aminoacylation	R-HSA-379726	9.534471e-01	0.021	0	0
Signaling by FLT3 ITD and TKD mutants	R-HSA-9703648	9.541519e-01	0.020	0	0
Assembly of active LPL and LIPC lipase complexes	R-HSA-8963889	9.541519e-01	0.020	0	0
Mitochondrial RNA degradation	R-HSA-9836573	9.541519e-01	0.020	0	0
Plasma lipoprotein assembly	R-HSA-8963898	9.541519e-01	0.020	0	0
Collagen formation	R-HSA-1474290	9.550255e-01	0.020	0	0
Asparagine N-linked glycosylation	R-HSA-446203	9.551961e-01	0.020	0	0
PI-3K cascade:FGFR2	R-HSA-5654695	9.586329e-01	0.018	0	0
Hyaluronan degradation	R-HSA-2160916	9.586329e-01	0.018	0	0
MicroRNA (miRNA) biogenesis	R-HSA-203927	9.586329e-01	0.018	0	0
Laminin interactions	R-HSA-3000157	9.586329e-01	0.018	0	0
PIWI-interacting RNA (piRNA) biogenesis	R-HSA-5601884	9.586329e-01	0.018	0	0
IRS-mediated signalling	R-HSA-112399	9.623885e-01	0.017	0	0
Transcriptional regulation of white adipocyte differentiation	R-HSA-381340	9.625631e-01	0.017	0	0
MET activates PTK2 signaling	R-HSA-8874081	9.626761e-01	0.017	0	0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes	R-HSA-9931510	9.626761e-01	0.017	0	0
Sphingolipid catabolism	R-HSA-9845614	9.626761e-01	0.017	0	0
Abacavir ADME	R-HSA-2161522	9.626761e-01	0.017	0	0
Regulation of RUNX1 Expression and Activity	R-HSA-8934593	9.626761e-01	0.017	0	0
Incretin synthesis, secretion, and inactivation	R-HSA-400508	9.640041e-01	0.016	0	0
Cleavage of the damaged pyrimidine	R-HSA-110329	9.640041e-01	0.016	0	0
Depyrimidination	R-HSA-73928	9.640041e-01	0.016	0	0
Ca2+ pathway	R-HSA-4086398	9.661074e-01	0.015	0	0
Packaging Of Telomere Ends	R-HSA-171306	9.663244e-01	0.015	0	0
RNA Polymerase I Promoter Opening	R-HSA-73728	9.663244e-01	0.015	0	0
Signaling by BMP	R-HSA-201451	9.663244e-01	0.015	0	0
Signaling by FGFR3 in disease	R-HSA-5655332	9.663244e-01	0.015	0	0
Maturation of hRSV A proteins	R-HSA-9828806	9.663244e-01	0.015	0	0
Extracellular matrix organization	R-HSA-1474244	9.672722e-01	0.014	0	0
Signaling by FGFR in disease	R-HSA-1226099	9.684275e-01	0.014	0	0
DAP12 interactions	R-HSA-2172127	9.697196e-01	0.013	0	0
Surfactant metabolism	R-HSA-5683826	9.697196e-01	0.013	0	0
HCMV Late Events	R-HSA-9610379	9.697482e-01	0.013	0	0
TP53 Regulates Transcription of Cell Death Genes	R-HSA-5633008	9.705987e-01	0.013	0	0
mitochondrial fatty acid beta-oxidation of saturated fatty acids	R-HSA-77286	9.722388e-01	0.012	0	0
Vasopressin regulates renal water homeostasis via Aquaporins	R-HSA-432040	9.722388e-01	0.012	0	0
IRS-related events triggered by IGF1R	R-HSA-2428928	9.723925e-01	0.012	0	0
Collagen degradation	R-HSA-1442490	9.723925e-01	0.012	0	0
Glucagon-type ligand receptors	R-HSA-420092	9.725865e-01	0.012	0	0
Downstream signaling of activated FGFR3	R-HSA-5654708	9.725865e-01	0.012	0	0
Regulation of pyruvate dehydrogenase (PDH) complex	R-HSA-204174	9.725865e-01	0.012	0	0
Base Excision Repair	R-HSA-73884	9.740003e-01	0.011	0	0
Inactivation, recovery and regulation of the phototransduction cascade	R-HSA-2514859	9.745550e-01	0.011	0	0
Thrombin signalling through proteinase activated receptors (PARs)	R-HSA-456926	9.752665e-01	0.011	0	0
Downstream signaling of activated FGFR4	R-HSA-5654716	9.752665e-01	0.011	0	0
Energy dependent regulation of mTOR by LKB1-AMPK	R-HSA-380972	9.752665e-01	0.011	0	0
Aspartate and asparagine metabolism	R-HSA-8963693	9.776847e-01	0.010	0	0
Regulation of cholesterol biosynthesis by SREBP (SREBF)	R-HSA-1655829	9.779612e-01	0.010	0	0
Phospholipid metabolism	R-HSA-1483257	9.781743e-01	0.010	0	0
IGF1R signaling cascade	R-HSA-2428924	9.781797e-01	0.010	0	0
Insulin receptor signalling cascade	R-HSA-74751	9.781797e-01	0.010	0	0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	9.798374e-01	0.009	0	0
Developmental Cell Lineages of the Exocrine Pancreas	R-HSA-9820448	9.798501e-01	0.009	0	0
DAG1 glycosylations	R-HSA-8931838	9.798666e-01	0.009	0	0
Signaling by WNT in cancer	R-HSA-4791275	9.798666e-01	0.009	0	0
Recognition and association of DNA glycosylase with site containing an affected purine	R-HSA-110330	9.798666e-01	0.009	0	0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	R-HSA-983695	9.801830e-01	0.009	0	0
Assembly of the ORC complex at the origin of replication	R-HSA-68616	9.818352e-01	0.008	0	0
Cardiogenesis	R-HSA-9733709	9.818352e-01	0.008	0	0
Recycling of bile acids and salts	R-HSA-159418	9.818352e-01	0.008	0	0
Signaling by FGFR2 in disease	R-HSA-5655253	9.820859e-01	0.008	0	0
Azathioprine ADME	R-HSA-9748787	9.820859e-01	0.008	0	0
SLC-mediated transport of amino acids	R-HSA-9958863	9.827992e-01	0.008	0	0
The phototransduction cascade	R-HSA-2514856	9.836001e-01	0.007	0	0
Vitamin B5 (pantothenate) metabolism	R-HSA-199220	9.836115e-01	0.007	0	0
Miscellaneous transport and binding events	R-HSA-5223345	9.836115e-01	0.007	0	0
Heme degradation	R-HSA-189483	9.836115e-01	0.007	0	0
Collagen biosynthesis and modifying enzymes	R-HSA-1650814	9.841193e-01	0.007	0	0
Degradation of the extracellular matrix	R-HSA-1474228	9.842450e-01	0.007	0	0
Hyaluronan metabolism	R-HSA-2142845	9.852142e-01	0.006	0	0
Amino acids regulate mTORC1	R-HSA-9639288	9.862642e-01	0.006	0	0
Downstream signaling of activated FGFR2	R-HSA-5654696	9.866602e-01	0.006	0	0
Base-Excision Repair, AP Site Formation	R-HSA-73929	9.874332e-01	0.005	0	0
ECM proteoglycans	R-HSA-3000178	9.875221e-01	0.005	0	0
Metabolism of cofactors	R-HSA-8978934	9.875221e-01	0.005	0	0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation	R-HSA-163841	9.877931e-01	0.005	0	0
FGFR2 mutant receptor activation	R-HSA-1839126	9.879649e-01	0.005	0	0
Integration of energy metabolism	R-HSA-163685	9.883734e-01	0.005	0	0
Voltage gated Potassium channels	R-HSA-1296072	9.891420e-01	0.005	0	0
SIRT1 negatively regulates rRNA expression	R-HSA-427359	9.891420e-01	0.005	0	0
TRAF6 mediated IRF7 activation	R-HSA-933541	9.891420e-01	0.005	0	0
Cleavage of the damaged purine	R-HSA-110331	9.891420e-01	0.005	0	0
NCAM1 interactions	R-HSA-419037	9.891420e-01	0.005	0	0
SLC-mediated transport of organic cations	R-HSA-549127	9.891420e-01	0.005	0	0
Metabolism of folate and pterines	R-HSA-196757	9.891420e-01	0.005	0	0
Depurination	R-HSA-73927	9.902041e-01	0.004	0	0
Leishmania infection	R-HSA-9658195	9.917966e-01	0.004	0	0
Parasitic Infection Pathways	R-HSA-9824443	9.917966e-01	0.004	0	0
Triglyceride metabolism	R-HSA-8979227	9.919681e-01	0.004	0	0
Maturation of TCA enzymes and regulation of TCA cycle	R-HSA-9854311	9.920269e-01	0.003	0	0
Peptide hormone metabolism	R-HSA-2980736	9.921797e-01	0.003	0	0
Chromatin modifications during the maternal to zygotic transition (MZT)	R-HSA-9821002	9.928069e-01	0.003	0	0
Aflatoxin activation and detoxification	R-HSA-5423646	9.928069e-01	0.003	0	0
Maturation of spike protein	R-HSA-9694548	9.928069e-01	0.003	0	0
Nuclear Receptor transcription pathway	R-HSA-383280	9.929521e-01	0.003	0	0
Aquaporin-mediated transport	R-HSA-445717	9.932934e-01	0.003	0	0
Pyrimidine catabolism	R-HSA-73621	9.947185e-01	0.002	0	0
Amine ligand-binding receptors	R-HSA-375280	9.952353e-01	0.002	0	0
Glycerophospholipid biosynthesis	R-HSA-1483206	9.952454e-01	0.002	0	0
ADORA2B mediated anti-inflammatory cytokines production	R-HSA-9660821	9.957016e-01	0.002	0	0
Synthesis of PC	R-HSA-1483191	9.965018e-01	0.002	0	0
GPER1 signaling	R-HSA-9634597	9.968442e-01	0.001	0	0
Plasma lipoprotein remodeling	R-HSA-8963899	9.968442e-01	0.001	0	0
Role of phospholipids in phagocytosis	R-HSA-2029485	9.969427e-01	0.001	0	0
Fatty acyl-CoA biosynthesis	R-HSA-75105	9.970442e-01	0.001	0	0
Chemokine receptors bind chemokines	R-HSA-380108	9.971531e-01	0.001	0	0
G alpha (q) signalling events	R-HSA-416476	9.971632e-01	0.001	0	0
Diseases associated with O-glycosylation of proteins	R-HSA-3906995	9.973033e-01	0.001	0	0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	R-HSA-2162123	9.974318e-01	0.001	0	0
Cytosolic sulfonation of small molecules	R-HSA-156584	9.976832e-01	0.001	0	0
Aspirin ADME	R-HSA-9749641	9.977564e-01	0.001	0	0
Platelet homeostasis	R-HSA-418346	9.979536e-01	0.001	0	0
ROS and RNS production in phagocytes	R-HSA-1222556	9.979539e-01	0.001	0	0
Paracetamol ADME	R-HSA-9753281	9.984658e-01	0.001	0	0
Bile acid and bile salt metabolism	R-HSA-194068	9.985163e-01	0.001	0	0
Mitochondrial Fatty Acid Beta-Oxidation	R-HSA-77289	9.985781e-01	0.001	0	0
Interleukin-10 signaling	R-HSA-6783783	9.985864e-01	0.001	0	0
Antimicrobial peptides	R-HSA-6803157	9.986315e-01	0.001	0	0
Developmental Lineage of Pancreatic Acinar Cells	R-HSA-9925561	9.987117e-01	0.001	0	0
Dectin-2 family	R-HSA-5621480	9.987516e-01	0.001	0	0
Potassium Channels	R-HSA-1296071	9.988029e-01	0.001	0	0
Regulation of lipid metabolism by PPARalpha	R-HSA-400206	9.989776e-01	0.000	0	0
Amino acid transport across the plasma membrane	R-HSA-352230	9.989841e-01	0.000	0	0
Synthesis of bile acids and bile salts	R-HSA-192105	9.990763e-01	0.000	0	0
Aerobic respiration and respiratory electron transport	R-HSA-1428517	9.992492e-01	0.000	0	0
Mitochondrial ribosome-associated quality control	R-HSA-9937383	9.993476e-01	0.000	0	0
Xenobiotics	R-HSA-211981	9.993933e-01	0.000	0	0
PPARA activates gene expression	R-HSA-1989781	9.996320e-01	0.000	0	0
COPII-mediated vesicle transport	R-HSA-204005	9.996732e-01	0.000	0	0
FCGR3A-mediated IL10 synthesis	R-HSA-9664323	9.996891e-01	0.000	0	0
Retinoid metabolism and transport	R-HSA-975634	9.997053e-01	0.000	0	0
Metabolism of porphyrins	R-HSA-189445	9.997053e-01	0.000	0	0
FCGR activation	R-HSA-2029481	9.997120e-01	0.000	0	0
Mitochondrial translation elongation	R-HSA-5389840	9.998027e-01	0.000	0	0
Citric acid cycle (TCA cycle)	R-HSA-71403	9.998049e-01	0.000	0	0
Mitochondrial translation initiation	R-HSA-5368286	9.998368e-01	0.000	0	0
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	9.998556e-01	0.000	0	0
Cholesterol biosynthesis	R-HSA-191273	9.998569e-01	0.000	0	0
Metabolism of fat-soluble vitamins	R-HSA-6806667	9.998950e-01	0.000	0	0
Biosynthesis of DHA-derived SPMs	R-HSA-9018677	9.998950e-01	0.000	0	0
Formation of the cornified envelope	R-HSA-6809371	9.999223e-01	0.000	0	0
Peroxisomal lipid metabolism	R-HSA-390918	9.999229e-01	0.000	0	0
Mitochondrial translation termination	R-HSA-5419276	9.999480e-01	0.000	0	0
Bacterial Infection Pathways	R-HSA-9824439	9.999560e-01	0.000	0	0
Class B/2 (Secretin family receptors)	R-HSA-373080	9.999626e-01	0.000	0	0
Peptide ligand-binding receptors	R-HSA-375276	9.999703e-01	0.000	0	0
Metabolism of carbohydrates and carbohydrate derivatives	R-HSA-71387	9.999758e-01	0.000	0	0
Anti-inflammatory response favouring Leishmania parasite infection	R-HSA-9662851	9.999801e-01	0.000	0	0
Leishmania parasite growth and survival	R-HSA-9664433	9.999801e-01	0.000	0	0
Mitochondrial translation	R-HSA-5368287	9.999834e-01	0.000	0	0
Role of LAT2/NTAL/LAB on calcium mobilization	R-HSA-2730905	9.999836e-01	0.000	0	0
Metabolism of nucleotides	R-HSA-15869	9.999921e-01	0.000	0	0
Visual phototransduction	R-HSA-2187338	9.999934e-01	0.000	0	0
Transport of small molecules	R-HSA-382551	9.999945e-01	0.000	0	0
G alpha (s) signalling events	R-HSA-418555	9.999955e-01	0.000	0	0
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	9.999968e-01	0.000	0	0
FCERI mediated MAPK activation	R-HSA-2871796	9.999972e-01	0.000	0	0
Respiratory electron transport	R-HSA-611105	9.999976e-01	0.000	0	0
Sphingolipid metabolism	R-HSA-428157	9.999982e-01	0.000	0	0
FCERI mediated Ca+2 mobilization	R-HSA-2871809	9.999983e-01	0.000	0	0
G alpha (i) signalling events	R-HSA-418594	9.999991e-01	0.000	0	0
Arachidonate metabolism	R-HSA-2142753	9.999996e-01	0.000	0	0
Cell surface interactions at the vascular wall	R-HSA-202733	9.999996e-01	0.000	0	0
Drug ADME	R-HSA-9748784	9.999996e-01	0.000	0	0
Nucleotide catabolism	R-HSA-8956319	9.999996e-01	0.000	0	0
GPCR downstream signalling	R-HSA-388396	9.999997e-01	0.000	0	0
O-linked glycosylation	R-HSA-5173105	9.999999e-01	0.000	0	0
Biosynthesis of specialized proresolving mediators (SPMs)	R-HSA-9018678	9.999999e-01	0.000	0	0
Metabolism of steroids	R-HSA-8957322	1.000000e+00	0.000	0	0
Keratinization	R-HSA-6805567	1.000000e+00	0.000	0	0
Metabolism of vitamins and cofactors	R-HSA-196854	1.000000e+00	0.000	0	0
SLC-mediated transmembrane transport	R-HSA-425407	1.000000e+00	0.000	0	0
Diseases of glycosylation	R-HSA-3781865	1.000000e+00	0.000	0	0
Metabolism of amino acids and derivatives	R-HSA-71291	1.000000e+00	0.000	0	0
Cytochrome P450 - arranged by substrate type	R-HSA-211897	1.000000e+00	0.000	0	0
Signaling by GPCR	R-HSA-372790	1.000000e+00	0.000	0	0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	R-HSA-198933	1.000000e+00	0.000	0	0
Glycosaminoglycan metabolism	R-HSA-1630316	1.000000e+00	0.000	0	0
Phase I - Functionalization of compounds	R-HSA-211945	1.000000e+00	0.000	0	0
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	1.000000e+00	0.000	0	0
Fatty acid metabolism	R-HSA-8978868	1.000000e+00	0.000	0	0
Phase II - Conjugation of compounds	R-HSA-156580	1.000000e+00	0.000	0	0
Diseases of metabolism	R-HSA-5668914	1.000000e+00	0.000	0	0
Metabolism of lipids	R-HSA-556833	1.000000e+00	-0.000	0	0
Metabolism	R-HSA-1430728	1.000000e+00	-0.000	0	0
Biological oxidations	R-HSA-211859	1.000000e+00	-0.000	0	0
GPCR ligand binding	R-HSA-500792	1.000000e+00	-0.000	0	0
Sensory Perception	R-HSA-9709957	1.000000e+00	-0.000	0	0
Golgi Cisternae Pericentriolar Stack Reorganization	R-HSA-162658	1.000000e+00	0.000	1	1
Activation of NIMA Kinases NEK9, NEK6, NEK7	R-HSA-2980767	1.000000e+00	0.000	1	1
Mitotic Metaphase/Anaphase Transition	R-HSA-68881	1.000000e+00	0.000	1	1