PKCA

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities

T Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

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substrate_uniprot site source substrate_genes site_seq
A0A2R8Y4L2 S95 Sugiyama HNRNPA1L3 HNRNPA1P48 RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NMY6 S26 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI
B6ZGS9 S135 GPS6 NR1H4 hCG_20893 GASAGRIKGDELCVVCGDRAsGYHYNALTCEGCKGFFRRsI
B6ZGS9 S154 GPS6 NR1H4 hCG_20893 AsGYHYNALTCEGCKGFFRRsITKNAVYKCKNGGNCVMDMY
O00161 S161 GPS6|SIGNOR|ELM|iPTMNet|EPSD SNAP23 KRItNDAREDEMEENLtQVGsILGNLKDMALNIGNEIDAQN
O00161 S23 GPS6|SIGNOR|ELM|iPTMNet|EPSD SNAP23 NLssEEIQQRAHQITDEsLEstRRILGLAIEsQDAGIKtIt
O00161 T24 GPS6|SIGNOR|ELM|iPTMNet|EPSD SNAP23 LssEEIQQRAHQITDEsLEstRRILGLAIEsQDAGIKtItM
O00168 S88 EPSD|PSP FXYD1 PLM QRTGEPDEEEGtFRssIRRLstRRR________________
O00571 S82 Sugiyama DDX3X DBX DDX3 ssKDKDAyssFGsRsDsRGKssFFsDRGsGsRGRFDDRGRs
O14493 S194 EPSD|PSP CLDN4 CPER CPETR1 WBSCR8 LLLGGGLLCCNCPPRtDKPYsAKYSAARsAAAsNyV_____
O14745 S162 GPS6|ELM|EPSD|PSP NHERF1 NHERF SLC9A3R1 KSHPEQRELRPRLCtMKKGPsGYGFNLHSDKSKPGQFIRsV
O14745 S339 EPSD|PSP NHERF1 NHERF SLC9A3R1 PILDFNISLAMAKERAHQKRssKRAPQMDWSKKNELFSNL_
O14745 S340 EPSD|PSP NHERF1 NHERF SLC9A3R1 ILDFNISLAMAKERAHQKRssKRAPQMDWSKKNELFSNL__
O14745 S77 EPSD|PSP NHERF1 NHERF SLC9A3R1 DRLVEVNGENVEKETHQQVVsRIRAALNAVRLLVVDPEtDE
O14920 S177 EPSD|PSP IKBKB IKKB EQRLIHKIIDLGYAKELDQGsLCTsFVGTLQyLAPELLEQQ
O14920 S181 EPSD|PSP IKBKB IKKB IHKIIDLGYAKELDQGsLCTsFVGTLQyLAPELLEQQKyTV
O14939 S243 GPS6|SIGNOR|ELM|EPSD|PSP PLD2 CCGRDQVCYRWSKRWLVVKDsFLLYMCLEtGAISFVQLFDP
O14939 T252 GPS6|SIGNOR|ELM|EPSD|PSP PLD2 RWSKRWLVVKDsFLLYMCLEtGAISFVQLFDPGFEVQVGKR
O14974 S910 Sugiyama PPP1R12A MBS MYPT1 yETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDST
O14986 S413 SIGNOR PIP5K1B STM7 SRVFKKIQALKASPSKKRCNsIAALKATSQEIVSSISQEWK
O15217 T193 SIGNOR|EPSD|PSP GSTA4 NILSAFPFLQEYTVKLsNIPtIKRFLEPGSKKKPPPDEIYV
O15350 S388 SIGNOR|EPSD|PSP TP73 P73 LMKLKESLELMELVPQPLVDsYRQQQQLLQRPSHLQPPSYG
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O15446 S64 Sugiyama POLR1G ASE1 CAST CD3EAP PAF49 LIQAPADFAPECFNGRHVPLsGsQIVKGKLAGKRHRyRVLS
O15519 S193 SIGNOR|EPSD|PSP CFLAR CASH CASP8AP1 CLARP MRIT QSVQGAGTSYRNVLQAAIQKsLKDPSNNFRLHNGRSKEQRL
O43526 S551 SIGNOR|iPTMNet|EPSD KCNQ2 DLTPGLKVSIRAVCVMRFLVsKRKFKEsLRPYDVMDVIEQY
O43526 S558 SIGNOR|iPTMNet|EPSD KCNQ2 VSIRAVCVMRFLVsKRKFKEsLRPYDVMDVIEQYSAGHLDM
O43526 T217 PSP KCNQ2 LRSLRFLQILRMIRMDRRGGtWKLLGSVVYAHSKELVTAWY
O43823 S323 Sugiyama AKAP8 AKAP95 RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE
O60220 S94 Sugiyama TIMM8A DDP DDP1 TIM8A SQFILNRLEQTQKSKPVFSEsLsD_________________
O60479 S137 iPTMNet|EPSD DLX3 AEVRMVNGKPKKVRKPRtIYssYQLAALQRRFQKAQYLALP
O60479 S138 SIGNOR|iPTMNet|EPSD DLX3 EVRMVNGKPKKVRKPRtIYssYQLAALQRRFQKAQYLALPE
O60479 S182 iPTMNet|EPSD DLX3 LAAQLGLTQTQVKIWFQNRRsKFKKLYKNGEVPLEHSPNNS
O60479 T134 SIGNOR|iPTMNet|EPSD DLX3 EPEAEVRMVNGKPKKVRKPRtIYssYQLAALQRRFQKAQYL
O60500 T1120 SIGNOR|EPSD|PSP NPHS1 NPHN KTEAGSEEDRVRNEYEESQWtGERDtQSSTVSTTEAEPYYR
O60500 T1125 SIGNOR|EPSD|PSP NPHS1 NPHN SEEDRVRNEYEESQWtGERDtQSSTVSTTEAEPYYRSLRDF
O60674 S518 SIGNOR|PSP JAK2 CCPPKPKDKSNLLVFRTNGVsDVPtsPTLQRPTHMNQMVFH
O60674 T174 SIGNOR|PSP JAK2 FAQWRHDFVHGWIKVPVTHEtQEECLGMAVLDMMRIAKEND
O60716 S879 EPSD|PSP CTNND1 KIAA0384 sQssHsyDDstLPLIDRNQKsDKKPDREEIQMSNMGsNtKs
O60825 T475 SIGNOR|iPTMNet|EPSD PFKFB2 KNQTPVRMRRNsFtPLsssNtIRRPRNYsVGsRPLKPLsPL
O60841 S196 Sugiyama EIF5B IF2 KIAA0741 ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN
O60841 S222 Sugiyama EIF5B IF2 KIAA0741 KNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAEKKERERKK
O60869 T91 SIGNOR|iPTMNet|EPSD EDF1 DRVTLEVGKVIQQGRQSKGLtQKDLATKINEKPQVIADyES
O60928 S201 SIGNOR|EPSD|PSP KCNJ13 MDGKPNLIFQVANTRPSPLTsVRVSAVLYQERENGKLYQTS
O60941 T179 EPSD|PSP DTNB NGLMIFSKFDQFLKEVLKLPtAVFEGPSFGYTEHSVRTCFP
O60941 T212 EPSD|PSP DTNB HSVRTCFPQQRKIMLNMFLDtMMADPPPQCLVWLPLMHRLA
O60941 T69 EPSD|PSP DTNB NLHLVDIWNMIEAFRDNGLNtLDHTTEISVSRLETVISSIY
O75144 S285 SIGNOR|PSP ICOSLG B7H2 B7RP1 ICOSL KIAA0653 LLVVVAVAIGWVCRDRCLQHsYAGAWAVsPETELTGHV___
O75376 S70 EPSD|PSP NCOR1 KIAA1047 VSQASQLLQQQQQQQLRRRPsLLSEFHPGSDRPQERRtsyE
O75385 S423 SIGNOR ULK1 KIAA0722 sPsPPCsssPsPsGRAGPFSsSRCGASVPIPVPTQVQNYQR
O75400 T948 Sugiyama PRPF40A FBP11 FLAF1 FNBP3 HIP10 HYPA HSPC225 GNWDtsGsELsEGELEKRRRtLLEQLDDDQ___________
O75469 T408 EPSD|PSP NR1I2 PXR FLFLKIMAMLTELRSINAQHtQRLLRIQDIHPFAtPLMQEL
O75643 S26 Sugiyama SNRNP200 ASCC3L1 BRR2 HELIC2 KIAA0788 ARsLQYEYKANsNLVLQADRsLIDRTRRDEPTGEVLsLVGK
O75689 S87 SIGNOR|iPTMNet|EPSD|PSP ADAP1 CENTA1 EAQVEFMASHGNDAARARFEsKVPSFYYRPTPSDCQLLREQ
O75689 T276 SIGNOR|iPTMNet|EPSD|PSP ADAP1 CENTA1 EGYMEKTGPKQTEGFRKRWFtMDDRRLMYFKDPLDAFARGE
O75955 S315 PSP FLOT1 ERLAEAEKSQLIMQAEAEAAsVRMRGEAEAFAIGARARAEA
O76090 S358 EPSD|PSP BEST1 VMD2 WNKPEPQPPYTAASAQFRRAsFMGSTFNISLNKEEMEFQPN
O94759 S39 PSP TRPM2 EREG1 KNP3 LTRPC2 TRPC7 GLPRRVTDLGMVSNLRRSNssLFKSWRLQCPFGNNDKQESL
O94806 S731 EPSD|PSP PRKD3 EPK2 PRKCN EPFPQVKLCDFGFARIIGEKsFRRsVVGtPAyLAPEVLRSK
O94901 S113 SIGNOR SUN1 KIAA0810 UNC84A QRRSTNKSAFSINHVSRQVTsSGVSHGGTVSLQDAVTRRPP
O94901 S55 EPSD|PSP SUN1 KIAA0810 UNC84A DFETEHKLDPVFDsPRMSRRsLRLATTACTLGDGEAVGADS
O94992 S158 EPSD HEXIM1 CLP1 EDG1 HIS1 MAQ1 EEEWGQQQRQLGKKKHRRRPsKKKRHWKPYYKLTWEEKKKF
O95243 S165 SIGNOR|EPSD|PSP MBD4 MED1 VLSKRGIKSRYKDCSMAALTsHLQNQSNNSNWNLRTRSKCK
O95243 S262 SIGNOR|EPSD|PSP MBD4 MED1 PIKKTKKGCRKsCSGFVQSDsKRESVCNKADAESEPVAQKS
O95471 S204 EPSD|PSP CLDN7 CEPTRL2 CPETRL2 CSCPGNESKAGYRVPRSYPKsNssKEYV_____________
O95644 S245 EPSD NFATC1 NFAT2 NFATC LGACtLLGsPRHsPstsPRAsVTEESWLGARssRPAsPCNK
O95644 S256 iPTMNet|EPSD NFATC1 NFAT2 NFATC HsPstsPRAsVTEESWLGARssRPAsPCNKRKYsLNGRQPP
O95644 S269 EPSD NFATC1 NFAT2 NFATC ESWLGARssRPAsPCNKRKYsLNGRQPPysPHHsPtPSPHG
O95644 S294 SIGNOR|EPSD NFATC1 NFAT2 NFATC QPPysPHHsPtPSPHGsPRVsVTDDSWLGNTTQYTSSAIVA
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95714 S2928 Sugiyama HERC2 ILLGRIRAEEEDLAAVPFLAsDNEEEEDEKGNSGsLIRKKA
O95757 S587 Sugiyama HSPA4L APG1 HSPH3 OSP94 RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM
O95786 S8 EPSD|PSP RIGI DDX58 _____________MTTEQRRsLQAFQDYIRKTLDPTYILSY
O95786 T170 EPSD|PSP RIGI DDX58 AGAEKLVECLLRSDKENWPKtLKLALEKERNKFSELWIVEK
O95832 T191 PSP CLDN1 CLD1 SEMP1 UNQ481/PRO944 AASLCLLGGALLCCSCPRKTtSYPTPRPYPKPAPSSGKDyV
O96004 S109 SIGNOR|ELM|iPTMNet|EPSD HAND1 BHLHA27 EHAND GGRLGRRKGsGPKKERRRtEsINSAFAELRECIPNVPADTK
O96004 S98 SIGNOR|ELM|iPTMNet|EPSD HAND1 BHLHA27 EHAND PGQSPGRLEALGGRLGRRKGsGPKKERRRtEsINSAFAELR
O96004 T107 SIGNOR|ELM|iPTMNet|EPSD HAND1 BHLHA27 EHAND ALGGRLGRRKGsGPKKERRRtEsINSAFAELRECIPNVPAD
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00491 S176 Sugiyama PNP NP GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA
P00533 T678 GPS6|SIGNOR|ELM|EPSD|PSP EGFR ERBB ERBB1 HER1 LVVALGIGLFMRRRHIVRKRtLRRLLQERELVEPLtPsGEA
P00558 S415 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GGGAsLELLEGKVLPGVDALsNI__________________
P00749 S158 GPS6|ELM|EPSD|PSP PLAU GLKLLVQECMVHDCADGKKPsSPPEELKFQCGQKTLRPRFK
P00749 S323 GPS6|ELM|EPSD|PSP PLAU MYNDPQFGTSCEITGFGKENsTDYLYPEQLKMTVVKLISHR
P01589 S268 SIGNOR|ELM|EPSD|PSP IL2RA FLLISVLLLSGLTWQRRQRKsRRtI________________
P01589 T271 SIGNOR|ELM|EPSD|PSP IL2RA ISVLLLSGLTWQRRQRKsRRtI___________________
P01730 S433 EPSD|PSP CD4 GLGIFFCVRCRHRRRQAERMsQIKRLLsEKKTCQCPHRFQK
P01730 S440 EPSD|PSP CD4 VRCRHRRRQAERMsQIKRLLsEKKTCQCPHRFQKTCSPI__
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02545 S403 SIGNOR|ELM|iPTMNet|EPSD LMNA LMN1 EEERLRLsPsPtsQRsRGRAssHssQtQGGGsVtKKRKLEs
P02545 S404 SIGNOR|ELM|iPTMNet|EPSD LMNA LMN1 EERLRLsPsPtsQRsRGRAssHssQtQGGGsVtKKRKLEst
P02545 S437 Sugiyama LMNA LMN1 KKRKLEstEsRssFsQHARtsGRVAVEEVDEEGKFVRLRNK
P02545 S5 ELM LMNA LMN1 ________________METPsQRRAtRsGAQAsstPLsPtR
P02545 S525 SIGNOR|iPTMNet|EPSD LMNA LMN1 tHsPPTDLVWKAQNtWGCGNsLRtALINstGEEVAMRKLVR
P02545 S625 ELM LMNA LMN1 AQVGGPIssGssAssVtVtRsYRsVGGsGGGsFGDNLVtRS
P02545 T19 iPTMNet|EPSD LMNA LMN1 __METPsQRRAtRsGAQAsstPLsPtRItRLQEKEDLQELN
P02545 T199 ELM LMNA LMN1 AKKQLQDEMLRRVDAENRLQtMKEELDFQKNIysEELREtK
P02545 T416 ELM LMNA LMN1 QRsRGRAssHssQtQGGGsVtKKRKLEstEsRssFsQHARt
P02545 T480 ELM LMNA LMN1 EDQsMGNWQIKRQNGDDPLLtYRFPPKFTLKAGQVVTIWAA
P02671 S576 ELM FGA NtKEsssHHPGIAEFPsRGKsssYSKQFTssTSYNRGDstF
P02671 S577 ELM FGA tKEsssHHPGIAEFPsRGKsssYSKQFTssTSYNRGDstFE
P02671 S578 ELM FGA KEsssHHPGIAEFPsRGKsssYSKQFTssTSYNRGDstFES
P02671 S618 ELM FGA SKSYKMADEAGsEADHEGTHsTKRGHAKSRPVRDCDDVLQT
P02686 S141 SIGNOR|EPSD MBP QEDSAATSESLDVMASQKRPsQRHGsKyLATAstMDHARHG
P02686 S146 SIGNOR|EPSD MBP ATSESLDVMASQKRPsQRHGsKyLATAstMDHARHGFLPRH
P02686 S190 SIGNOR|EPSD MBP GILDsIGRFFGGDRGAPKRGsGKDSHHPARTAHyGsLPQKS
P02686 S249 SIGNOR|EPSD MBP tPRtPPPSQGKGRGLSLSRFsWGAEGQRPGFGYGGRAsDYK
P02686 S266 SIGNOR|EPSD MBP SRFsWGAEGQRPGFGYGGRAsDYKSAHKGFKGVDAQGtLsK
P02686 S285 SIGNOR|EPSD MBP AsDYKSAHKGFKGVDAQGtLsKIFKLGGRDsRSGsPMARR_
P02686 S295 SIGNOR|EPSD MBP FKGVDAQGtLsKIFKLGGRDsRSGsPMARR___________
P02786 S159 Sugiyama TFRC DFTGtIKLLNENsyVPREAGsQKDENLALyVENQFREFKLS
P02786 S24 GPS6|ELM|EPSD|PSP TFRC QARsAFsNLFGGEPLsytRFsLARQVDGDNsHVEMKLAVDE
P02786 S361 Sugiyama TFRC AAEKLFGNMEGDCPSDWKTDstCRMVTSESKNVKLTVSNVL
P02786 T143 Sugiyama TFRC yWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAGsQKDE
P04004 S381 SIGNOR|iPTMNet|EPSD|PSP VTN PRPsLAKKQRFRHRNRKGYRsQRGHsRGRNQNsRRPsRAtW
P04004 S386 EPSD|PSP VTN AKKQRFRHRNRKGYRsQRGHsRGRNQNsRRPsRAtWLsLFs
P04004 S393 EPSD|PSP VTN HRNRKGYRsQRGHsRGRNQNsRRPsRAtWLsLFssEEsNLG
P04004 S397 EPSD|PSP VTN KGYRsQRGHsRGRNQNsRRPsRAtWLsLFssEEsNLGANNY
P04049 S233 SIGNOR RAF1 RAF TMRRMRESVSRMPVssQHRystPHAFtFNtssPSSEGSLSQ
P04049 S43 SIGNOR|EPSD|PSP RAF1 RAF DGssCIsPtIVQQFGYQRRAsDDGKLtDPSKTSNTIRVFLP
P04049 S497 SIGNOR RAF1 RAF HEGLtVKIGDFGLAtVKsRWsGsQQVEQPTGSVLWMAPEVI
P04049 S499 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP RAF1 RAF GLtVKIGDFGLAtVKsRWsGsQQVEQPTGSVLWMAPEVIRM
P04049 S619 SIGNOR RAF1 RAF FPQILssIELLQHsLPKINRsAsEPsLHRAAHtEDINACtL
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04083 S27 GPS6|SIGNOR|ELM|EPSD|PSP ANXA1 ANX1 LPC1 FLKQAWFIENEEQEyVQtVKssKGGPGsAVsPyPtFNPssD
P04083 S28 ELM|EPSD|PSP ANXA1 ANX1 LPC1 LKQAWFIENEEQEyVQtVKssKGGPGsAVsPyPtFNPssDV
P04083 T24 ELM ANXA1 ANX1 LPC1 VsEFLKQAWFIENEEQEyVQtVKssKGGPGsAVsPyPtFNP
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04439 S359 SIGNOR|ELM|EPSD HLA-A HLAA RKGGsyTQAASSDSAQGSDVsLTACKV______________
P04626 T686 EPSD|PSP ERBB2 HER2 MLN19 NEU NGL VLGVVFGILIKRRQQKIRKYtMRRLLQETELVEPLtPsGAM
P04637 S371 SIGNOR|iPTMNet|EPSD|PSP TP53 P53 KDAQAGKEPGGSRAHssHLKsKKGQstsRHKKLMFKtEGPD
P04637 S376 EPSD|PSP TP53 P53 GKEPGGSRAHssHLKsKKGQstsRHKKLMFKtEGPDsD___
P04637 S378 iPTMNet|EPSD|PSP TP53 P53 EPGGSRAHssHLKsKKGQstsRHKKLMFKtEGPDsD_____
P04637 T377 EPSD|PSP TP53 P53 KEPGGSRAHssHLKsKKGQstsRHKKLMFKtEGPDsD____
P04792 S15 PSP HSPB1 HSP27 HSP28 ______MTERRVPFsLLRGPsWDPFRDWyPHsRLFDQAFGL
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792 S86 Sugiyama HSPB1 HSP27 HSP28 PAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAP
P05023 S16 SIGNOR ATP1A1 _____MGKGVGRDKyEPAAVsEQGDKKGKKGKKDRDMDELK
P05107 S745 GPS6|ELM|EPSD|PSP ITGB2 CD18 MFI7 ALIHLSDLREyRRFEKEKLKsQWNNDNPLFKsAtttVMNPK
P05107 S756 ELM ITGB2 CD18 MFI7 RRFEKEKLKsQWNNDNPLFKsAtttVMNPKFAES_______
P05107 T758 GPS6|SIGNOR|ELM|EPSD|PSP ITGB2 CD18 MFI7 FEKEKLKsQWNNDNPLFKsAtttVMNPKFAES_________
P05107 T760 GPS6|SIGNOR|ELM|EPSD|PSP ITGB2 CD18 MFI7 KEKLKsQWNNDNPLFKsAtttVMNPKFAES___________
P05114 S21 SIGNOR|ELM|iPTMNet|EPSD HMGN1 HMG14 MPKRKVssAEGAAKEEPKRRsARLsAKPPAKVEAKPKKAAA
P05114 S25 SIGNOR|ELM|iPTMNet|EPSD HMGN1 HMG14 KVssAEGAAKEEPKRRsARLsAKPPAKVEAKPKKAAAKDKS
P05114 S7 iPTMNet|EPSD HMGN1 HMG14 ______________MPKRKVssAEGAAKEEPKRRsARLsAK
P05204 S25 SIGNOR|iPTMNet|EPSD HMGN2 HMG17 KAEGDAKGDKAKVKDEPQRRsARLsAKPAPPKPEPKPKKAP
P05204 S29 SIGNOR|iPTMNet|EPSD HMGN2 HMG17 DAKGDKAKVKDEPQRRsARLsAKPAPPKPEPKPKKAPAKKG
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05455 S94 Sugiyama SSB KSKAELMEIsEDKTKIRRsPsKPLPEVTDEyKNDVKNRsVY
P05556 S785 EPSD|PSP ITGB1 FNRB MDF2 MSK12 KFEKEKMNAKWDtGENPIyKsAVttVVNPKyEGK_______
P05783 S53 SIGNOR|ELM|iPTMNet|EPSD KRT18 CYK18 PIG46 AsVyAGAGGsGsRIsVsRstsFRGGMGsGGLAtGIAGGLAG
P05783 S93 Sugiyama KRT18 CYK18 PIG46 GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S410 Sugiyama KRT8 CYK8 TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P06127 T434 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP CD5 LEU1 QRQWIGPTGMNQNMsFHRNHtAtVRsHAENPtASHVDNEys
P06127 T436 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP CD5 LEU1 QWIGPTGMNQNMsFHRNHtAtVRsHAENPtASHVDNEysQP
P06213 S1062 GPS6|SIGNOR|ELM|EPSD|PSP INSR ARDIIKGEAETRVAVKTVNEsAsLRERIEFLNEAsVMKGFT
P06213 S1064 GPS6|SIGNOR|ELM|EPSD|PSP INSR DIIKGEAETRVAVKTVNEsAsLRERIEFLNEAsVMKGFTCH
P06213 T1362 SIGNOR|EPSD INSR GRDGGSsLGFKRsyEEHIPytHMNGGKKNGRILtLPRSNPS
P06213 T1375 GPS6|ELM|EPSD INSR yEEHIPytHMNGGKKNGRILtLPRSNPS_____________
P06239 S42 SIGNOR|iPTMNet|EPSD|PSP LCK NCHYPIVPLDGKGTLLIRNGsEVRDPLVTYEGsNPPAsPLQ
P06401 S400 PSP PGR NR3C3 FQPPALKIKEEEEGAEASARsPRSYLVAGANPAAFPDFPLG
P06730 S209 SIGNOR|iPTMNet|EPSD EIF4E EIF4EL1 EIF4F LPPKIVIGyQsHADTAtKsGsttKNRFVV____________
P06748 S227 ELM NPM1 NPM SNQNGKDsKPsstPRsKGQEsFKKQEKtPKtPKGPssVEDI
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07307 S12 ELM ASGR2 CLEC4H2 _________MAKDFQDIQQLsSEENDHPFHQGEGPGTRRLN
P07355 S12 EPSD|PSP ANXA2 ANX2 ANX2L4 CAL1H LPC2D _________MstVHEILCKLsLEGDHstPPsAyGsVKAytN
P07355 S26 GPS6|SIGNOR|ELM|EPSD|PSP|Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07737 T65 Sugiyama PFN1 PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs
P07737 Y60 Sugiyama PFN1 FVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQ
P07814 S330 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KHRKNPIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGC
P07814 S739 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07949 T675 EPSD|PSP RET CDHF12 CDHR16 PTC FCIHCYHKFAHKPPISSAEMtFRRPAQAFPVsysssGARRP
P08034 S229 SIGNOR|ELM|iPTMNet|EPSD GJB1 CX32 VVYLIIRACARRAQRRSNPPsRKGsGFGHRLSPEyKQNEIN
P08034 S233 SIGNOR|ELM|iPTMNet|EPSD GJB1 CX32 IIRACARRAQRRSNPPsRKGsGFGHRLSPEyKQNEINKLLS
P08100 S334 SIGNOR|iPTMNet|EPSD RHO OPN2 RNCMLTTICCGKNPLGDDEAsAtVsKtETsQVAPA______
P08100 S338 SIGNOR RHO OPN2 LTTICCGKNPLGDDEAsAtVsKtETsQVAPA__________
P08100 S343 SIGNOR RHO OPN2 CGKNPLGDDEAsAtVsKtETsQVAPA_______________
P08100 T336 SIGNOR|iPTMNet|EPSD RHO OPN2 CMLTTICCGKNPLGDDEAsAtVsKtETsQVAPA________
P08183 S661 ELM|EPSD|PSP ABCB1 MDR1 PGY1 ADESKSEIDALEMssNDsRssLIRKRsTRRsVRGSQAQDRK
P08183 S667 ELM|EPSD|PSP ABCB1 MDR1 PGY1 EIDALEMssNDsRssLIRKRsTRRsVRGSQAQDRKLsTKEA
P08183 S671 ELM|EPSD|PSP ABCB1 MDR1 PGY1 LEMssNDsRssLIRKRsTRRsVRGSQAQDRKLsTKEALDES
P08195 S253 Sugiyama SLC3A2 MDU1 FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA
P08195 S296 Sugiyama SLC3A2 MDU1 DLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNYRGEN
P08238 S482 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER
P08238 T637 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL
P08253 S160 EPSD|PSP MMP2 CLG4A VDDAFARAFQVWSDVTPLRFsRIHDGEADIMINFGRWEHGD
P08253 S365 EPSD|PSP MMP2 CLG4A EGAPCVFPFTFLGNKYESCTsAGRSDGKMWCAttANYDDDR
P08253 T250 EPSD|PSP MMP2 CLG4A GEYCKFPFLFNGKEYNSCTDtGRSDGFLWCSTTYNFEKDGK
P08253 T377 EPSD|PSP MMP2 CLG4A GNKYESCTsAGRSDGKMWCAttANYDDDRKWGFCPDQGYSL
P08253 T378 EPSD|PSP MMP2 CLG4A NKYESCTsAGRSDGKMWCAttANYDDDRKWGFCPDQGYSLF
P08567 S113 GPS6|SIGNOR|ELM|EPSD|PSP PLEK P47 VRDIKKAIKCIEGGQKFARKstRRsIRLPEtIDLGALYLsM
P08567 S117 GPS6|SIGNOR|ELM|EPSD|PSP PLEK P47 KKAIKCIEGGQKFARKstRRsIRLPEtIDLGALYLsMKDTE
P08567 T114 ELM PLEK P47 RDIKKAIKCIEGGQKFARKstRRsIRLPEtIDLGALYLsMK
P08581 S985 SIGNOR|ELM|EPSD|PSP MET GsELVRYDARVHtPHLDRLVsARsVsPttEMVsNEsVDyRA
P08670 S10 SIGNOR|iPTMNet|EPSD|PSP VIM ___________MstRsVssssYRRMFGGPGtAsRPsssRsY
P08670 S22 SIGNOR VIM stRsVssssYRRMFGGPGtAsRPsssRsYVttsTRtYsLGs
P08670 S25 iPTMNet|EPSD VIM sVssssYRRMFGGPGtAsRPsssRsYVttsTRtYsLGsALR
P08670 S26 SIGNOR|iPTMNet|EPSD VIM VssssYRRMFGGPGtAsRPsssRsYVttsTRtYsLGsALRP
P08670 S27 SIGNOR VIM ssssYRRMFGGPGtAsRPsssRsYVttsTRtYsLGsALRPs
P08670 S34 SIGNOR|iPTMNet|EPSD VIM MFGGPGtAsRPsssRsYVttsTRtYsLGsALRPstsRsLyA
P08670 S39 SIGNOR|iPTMNet|EPSD VIM GtAsRPsssRsYVttsTRtYsLGsALRPstsRsLyAssPGG
P08670 S42 SIGNOR|iPTMNet|EPSD VIM sRPsssRsYVttsTRtYsLGsALRPstsRsLyAssPGGVyA
P08670 S5 EPSD|PSP VIM ________________MstRsVssssYRRMFGGPGtAsRPs
P08670 S51 SIGNOR VIM VttsTRtYsLGsALRPstsRsLyAssPGGVyAtRssAVRLR
P08670 S66 SIGNOR VIM PstsRsLyAssPGGVyAtRssAVRLRssVPGVRLLQDsVDF
P08670 S7 SIGNOR|iPTMNet|EPSD|PSP VIM ______________MstRsVssssYRRMFGGPGtAsRPsss
P08670 S8 EPSD|PSP VIM _____________MstRsVssssYRRMFGGPGtAsRPsssR
P08670 S9 SIGNOR|iPTMNet|EPSD|PSP VIM ____________MstRsVssssYRRMFGGPGtAsRPsssRs
P08684 S100 EPSD|PSP CYP3A4 CYP3A3 PVLAITDPDMIKtVLVKECYsVFtNRRPFGPVGFMKsAIsI
P08684 S116 EPSD|PSP CYP3A4 CYP3A3 KECYsVFtNRRPFGPVGFMKsAIsIAEDEEWKRLRsLLsPt
P08684 S119 EPSD|PSP CYP3A4 CYP3A3 YsVFtNRRPFGPVGFMKsAIsIAEDEEWKRLRsLLsPtFts
P08684 S131 EPSD|PSP CYP3A4 CYP3A3 VGFMKsAIsIAEDEEWKRLRsLLsPtFtsGKLKEMVPIIAQ
P08684 S134 EPSD|PSP CYP3A4 CYP3A3 MKsAIsIAEDEEWKRLRsLLsPtFtsGKLKEMVPIIAQYGD
P08684 S139 EPSD|PSP CYP3A4 CYP3A3 sIAEDEEWKRLRsLLsPtFtsGKLKEMVPIIAQYGDVLVRN
P08684 S259 EPSD|PSP CYP3A4 CYP3A3 CVFPREVTNFLRKSVKRMKEsRLEDtQKHRVDFLQLMIDSQ
P08684 S398 EPSD|PSP CYP3A4 CYP3A3 KKDVEINGMFIPKGVVVMIPsYALHRDPKYWTEPEKFLPER
P08684 S420 EPSD|PSP CYP3A4 CYP3A3 ALHRDPKYWTEPEKFLPERFsKKNKDNIDPYIYTPFGSGPR
P08684 T103 EPSD|PSP CYP3A4 CYP3A3 AITDPDMIKtVLVKECYsVFtNRRPFGPVGFMKsAIsIAED
P08684 T136 EPSD|PSP CYP3A4 CYP3A3 sAIsIAEDEEWKRLRsLLsPtFtsGKLKEMVPIIAQYGDVL
P08684 T264 EPSD|PSP CYP3A4 CYP3A3 EVTNFLRKSVKRMKEsRLEDtQKHRVDFLQLMIDSQNSKEt
P08684 T284 EPSD|PSP CYP3A4 CYP3A3 tQKHRVDFLQLMIDSQNSKEtESHKALSDLELVAQSIIFIF
P08684 T92 EPSD|PSP CYP3A4 CYP3A3 WGFYDGQQPVLAITDPDMIKtVLVKECYsVFtNRRPFGPVG
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P08754 S153 Sugiyama GNAI3 DGGVQACFSRsREYQLNDSAsyyLNDLDRISQSNyIPTQQD
P08833 S123 PSP IGFBP1 IBP1 ACVQESDASAPHAAEAGSPEsPEsTEITEEELLDNFHLMAP
P08833 S126 EPSD|PSP IGFBP1 IBP1 QESDASAPHAAEAGSPEsPEsTEITEEELLDNFHLMAPsEE
P08833 S144 EPSD|PSP IGFBP1 IBP1 PEsTEITEEELLDNFHLMAPsEEDHSILWDAISTYDGSKAL
P08833 S194 EPSD|PSP IGFBP1 IBP1 EPCRIELYRVVESLAKAQETsGEEIsKFYLPNCNKNGFYHS
P09038 S206 GPS6|EPSD FGF2 FGFB REKSDPHIKLQLQAEERGVVsIKGVCANRyLAMKEDGRLLA
P09211 S185 SIGNOR|EPSD|PSP GSTP1 FAEES3 GST3 VLAPGCLDAFPLLSAYVGRLsARPKLKAFLASPEyVNLPIN
P09211 S43 SIGNOR GSTP1 FAEES3 GST3 ADQGQSWKEEVVTVETWQEGsLKASCLyGQLPKFQDGDLtL
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09543 S9 ELM CNP ____________MNRGFsRKsHTFLPKIFFRKMsSSGAKDK
P09651 S360 Sugiyama HNRNPA1 HNRPA1 PyGGGGQyFAKPRNQGGyGGssssssyGsGRRF________
P09651 S368 Sugiyama HNRNPA1 HNRPA1 FAKPRNQGGyGGssssssyGsGRRF________________
P09651 S95 SIGNOR|Sugiyama HNRNPA1 HNRPA1 RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
P09693 S148 ELM|EPSD|PSP CD3G T3G VLAVGVYFIAGQDGVRQsRAsDKQTLLPNDQLyQPLKDRED
P09758 S303 GPS6|ELM|EPSD|PSP TACSTD2 GA733-1 M1S1 TROP2 VVVVALVAGMAVLVITNRRKsGKYKKVEIKELGELRKEPsL
P09758 S322 SIGNOR|PSP TACSTD2 GA733-1 M1S1 TROP2 KsGKYKKVEIKELGELRKEPsL___________________
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P10275 S579 EPSD|PSP AR DHTR NR3C4 TCLICGDEASGCHYGALTCGsCKVFFKRAAEGKQKYLCASR
P10276 S157 GPS6 RARA NR1B1 RNRCQYCRLQKCFEVGMSKEsVRNDRNKKKKEVPKPECSES
P10415 S24 iPTMNet|EPSD BCL2 AGRTGYDNREIVMKYIHYKLsQRGYEWDAGDVGAAPPGAAP
P10415 S70 GPS6|SIGNOR|EPSD|PSP BCL2 SSQPGHtPHPAASRDPVARtsPLQtPAAPGAAAGPALsPVP
P10588 S83 EPSD|PSP NR2F6 EAR2 ERBAL2 SSGKHYGVFTCEGCKSFFKRsIRRNLSYTCRSNRDCQIDQH
P10599 T100 EPSD|PSP TXN TRDX TRX TRX1 FKKGQKVGEFSGANKEKLEAtINELV_______________
P10721 S741 GPS6|SIGNOR|ELM|EPSD|PSP KIT SCFR yMDMKPGVsyVVPTKADKRRsVRIGsyIERDVTPAIMEDDE
P10721 S746 GPS6|SIGNOR|ELM|EPSD|PSP KIT SCFR PGVsyVVPTKADKRRsVRIGsyIERDVTPAIMEDDELALDL
P10721 S821 GPS6|SIGNOR|ELM|EPSD KIT SCFR THGRITKICDFGLARDIKNDsNyVVKGNARLPVKWMAPESI
P10721 S959 GPS6|SIGNOR|ELM|EPSD KIT SCFR LANCsPNRQKPVVDHSVRINsVGstAsSSQPLLVHDDV___
P11142 S153 Sugiyama HSPA8 HSC70 HSP73 HSPA10 AyLGKtVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNVLRII
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 T158 Sugiyama HSPA8 HSC70 HSP73 HSPA10 tVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtA
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11234 S198 SIGNOR|EPSD|PSP RALB TKKMSENKDKNGKKSSKNKKsFKERCCLL____________
P11387 S21 SIGNOR|EPSD|PSP TOP1 MsGDHLHNDsQIEADFRLNDsHKHKDKHKDREHRHKEHKKE
P11388 S29 ELM|iPTMNet|EPSD TOP2A TOP2 VNENMQVNKIKKNEDAKKRLsVERIYQKKTQLEHILLRPDT
P11473 S51 EPSD|PSP VDR NR1I1 ATGFHFNAMTCEGCKGFFRRsMKRKALFTCPFNGDCRITKD
P11831 S162 SIGNOR|EPSD|PSP SRF GRVKIKMEFIDNKLRRYttFsKRKTGIMKKAYELSTLTGTQ
P11831 T159 GPS6|SIGNOR|ELM|EPSD|PSP SRF KTRGRVKIKMEFIDNKLRRYttFsKRKTGIMKKAYELSTLT
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12931 S12 SIGNOR|iPTMNet|EPSD SRC SRC1 _________MGSNKSKPKDAsQRRRsLEPAENVHGAGGGAF
P12956 S77 PSP XRCC6 G22P1 LTPFDMSIQCIQSVYISKIIssDRDLLAVVFYGTEKDKNSV
P12956 S78 PSP XRCC6 G22P1 TPFDMSIQCIQSVYISKIIssDRDLLAVVFYGTEKDKNSVN
P13498 T147 SIGNOR|EPSD|PSP CYBA RGEQWTPIEPKPRERPQIGGtIKQPPsNPPPRPPAEARKKP
P13569 S641 PSP CFTR ABCC7 EGSSYFYGTFSELQNLQPDFsSKLMGCDSFDQFSAERRNsI
P13569 S660 EPSD|PSP CFTR ABCC7 FsSKLMGCDSFDQFSAERRNsILTETLHRFsLEGDAPVSWT
P13569 S686 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP CFTR ABCC7 LHRFsLEGDAPVSWTEtKKQsFKQTGEFGEKRKNsILNPIN
P13569 S737 EPSD|PSP CFTR ABCC7 TPLQMNGIEEDSDEPLERRLsLVPDSEQGEAILPRIsVIST
P13569 S790 SIGNOR|ELM|iPTMNet|EPSD CFTR ABCC7 LNLMTHSVNQGQNIHRKTTAsTRKVsLAPQANLTELDIYsR
P13569 S795 EPSD|PSP CFTR ABCC7 HSVNQGQNIHRKTTAsTRKVsLAPQANLTELDIYsRRLsQE
P13569 S813 EPSD|PSP CFTR ABCC7 KVsLAPQANLTELDIYsRRLsQEtGLEISEEINEEDLKECF
P13569 T682 PSP CFTR ABCC7 LTETLHRFsLEGDAPVSWTEtKKQsFKQTGEFGEKRKNsIL
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13726 S285 SIGNOR|ELM|EPSD|PSP F3 ILVIILAISLHKCRKAGVGQsWKENsPLNVs__________
P13726 S290 ELM|EPSD|PSP F3 LAISLHKCRKAGVGQsWKENsPLNVs_______________
P13796 S5 PSP LCP1 PLS2 ________________MARGsVsDEEMMELREAFAKVDtDG
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13987 T76 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF
P14136 S13 SIGNOR|ELM|iPTMNet|EPSD GFAP ________MERRRItsAARRsYVssGEMMVGGLAPGRRLGP
P14136 S17 ELM|iPTMNet|EPSD GFAP ____MERRRItsAARRsYVssGEMMVGGLAPGRRLGPGTRL
P14136 S38 SIGNOR|ELM|iPTMNet|EPSD GFAP GEMMVGGLAPGRRLGPGTRLsLARMPPPLPTRVDFSLAGAL
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314 T479 Sugiyama PRKCSH G19P1 KFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPSR
P14416 S228 PSP DRD2 VYIKIYIVLRRRRKRVNtKRssRAFRAHLRAPLKGNCTHPE
P14416 S229 PSP DRD2 YIKIYIVLRRRRKRVNtKRssRAFRAHLRAPLKGNCTHPED
P14598 S303 GPS6|SIGNOR|ELM|EPSD|PSP NCF1 NOXO2 SH3PXD1A sGQDVsQAQRQIKRGAPPRRssIRNAHsIHQRsRKRLsQDA
P14598 S304 GPS6|SIGNOR|ELM|EPSD|PSP NCF1 NOXO2 SH3PXD1A GQDVsQAQRQIKRGAPPRRssIRNAHsIHQRsRKRLsQDAY
P14598 S315 GPS6|SIGNOR|ELM|EPSD|PSP NCF1 NOXO2 SH3PXD1A KRGAPPRRssIRNAHsIHQRsRKRLsQDAYRRNsVRFLQQR
P14598 S320 GPS6|SIGNOR|ELM|EPSD|PSP NCF1 NOXO2 SH3PXD1A PRRssIRNAHsIHQRsRKRLsQDAYRRNsVRFLQQRRRQAR
P14598 S328 GPS6|SIGNOR|ELM|EPSD|PSP NCF1 NOXO2 SH3PXD1A AHsIHQRsRKRLsQDAYRRNsVRFLQQRRRQARPGPQsPGs
P14598 S348 GPS6|ELM|EPSD NCF1 NOXO2 SH3PXD1A sVRFLQQRRRQARPGPQsPGsPLEEERQtQRsKPQPAVPPR
P14598 S359 GPS6|SIGNOR|ELM|EPSD|PSP NCF1 NOXO2 SH3PXD1A ARPGPQsPGsPLEEERQtQRsKPQPAVPPRPsADLILNRCs
P14598 S370 GPS6|SIGNOR|ELM|EPSD|PSP NCF1 NOXO2 SH3PXD1A LEEERQtQRsKPQPAVPPRPsADLILNRCsESTKRKLASAV
P14598 S379 GPS6|SIGNOR|EPSD|PSP NCF1 NOXO2 SH3PXD1A sKPQPAVPPRPsADLILNRCsESTKRKLASAV_________
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14625 S514 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK
P14625 S515 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ
P14625 S64 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14625 S680 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 RIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDMLRR
P14625 T519 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 DHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIy
P15172 T115 SIGNOR|ELM|iPTMNet|EPSD MYOD1 BHLHC1 MYF3 MYOD LWACKACKRKTTNADRRKAAtMRERRRLSKVNEAFETLKRC
P15311 S535 Sugiyama EZR VIL2 EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P15311 S539 Sugiyama EZR VIL2 TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR
P15311 T533 Sugiyama EZR VIL2 NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15311 T567 SIGNOR|iPTMNet|EPSD|PSP EZR VIL2 RTHNDIIHNENMRQGRDKYKtLRQIRQGNTKQRIDEFEAL_
P15328 S79 Sugiyama FOLR1 FOLR PWRKNACCSTNTSQEAHKDVsyLyRFNWNHCGEMAPACKRH
P15336 S121 EPSD|PSP ATF2 CREB2 CREBP1 EDDIKKMPLDLsPLAtPIIRsKIEEPsVVEttHQDsPLPHP
P15382 S102 SIGNOR|iPTMNet|EPSD KCNE1 IESDAWQEKDKAYVQARVLEsYRSCYVVENHLAIEQPNTHL
P16070 S291 ELM CD44 LHR MDU2 MDU3 MIC4 TISAGWEPNEENEDERDRHLsFSGSGIDDDEDFISSTISTT
P16070 S672 GPS6|ELM|EPSD|PSP CD44 LHR MDU2 MDU3 MIC4 IILASLLALALILAVCIAVNsRRRCGQKKKLVINsGNGAVE
P16144 S1356 GPS6|ELM|EPSD|PSP ITGB4 DAQSGEDYDSFLMYSDDVLRsPSGsQRPsVSDDTGCGWKFE
P16144 S1360 GPS6|SIGNOR|ELM|EPSD|PSP ITGB4 GEDYDSFLMYSDDVLRsPSGsQRPsVSDDTGCGWKFEPLLG
P16144 S1364 GPS6|ELM|EPSD|PSP ITGB4 DSFLMYSDDVLRsPSGsQRPsVSDDTGCGWKFEPLLGEELD
P16144 S1494 SIGNOR|EPSD|PSP ITGB4 sPHVPHRVLstsstLTRDyNsLtRsEHsHsttLPRDystLt
P16150 S351 GPS6|ELM|EPSD|PSP SPN CD43 PDGEGssRRPtLtTFFGRRKsRQGsLAMEELKsGsGPsLKG
P16671 T92 EPSD|PSP CD36 GP3B GP4 NPQEVMMNSSNIQVKQRGPYtYRVRFLAKENVTQDAEDNTV
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17252 S657 GPS6|SIGNOR|ELM|EPSD PRKCA PKCA PRKACA LtPPDQLVIANIDQsDFEGFsyVNPQFVHPILQSAV_____
P17252 T250 GPS6|EPSD PRKCA PKCA PRKACA KLKPSDKDRRLsVEIWDWDRtTRNDFMGSLSFGVSELMKMP
P17252 T638 GPS6|SIGNOR|EPSD PRKCA PKCA PRKACA VCGKGAENFDKFFTRGQPVLtPPDQLVIANIDQsDFEGFsy
P17302 S262 SIGNOR GJA1 GJAL GKSDPyHATsGALsPAKDCGsQKyAyFNGCssPtAPLsPMs
P17302 S368 SIGNOR|iPTMNet|EPSD|PSP GJA1 GJAL AAGHELQPLAIVDQRPssRAssRAssRPRPDDLEI______
P17302 S372 PSP GJA1 GJAL ELQPLAIVDQRPssRAssRAssRPRPDDLEI__________
P17812 S462 SIGNOR|EPSD|PSP CTPS1 CTPS GQMGGTMRLGKRRtLFQTKNsVMRKLyGDADyLEERHRHRF
P17812 T455 SIGNOR|EPSD|PSP CTPS1 CTPS DMPEHNPGQMGGTMRLGKRRtLFQTKNsVMRKLyGDADyLE
P17844 S520 Sugiyama DDX5 G17P1 HELR HLR1 GKRGGFNTFRDRENYDRGYssLLKRDFGAKTQNGVYSAANY
P17844 S557 SIGNOR|ELM|iPTMNet|EPSD DDX5 G17P1 HELR HLR1 AANYTNGSFGSNFVSAGIQTsFRTGNPtGTYQNGYDSTQQY
P17987 S374 Sugiyama TCP1 CCT1 CCTA ERICDDELILIKNTKARTsAsIILRGANDFMCDEMERSLHD
P18031 S378 GPS6|ELM|EPSD|PSP PTPN1 PTP1B PYGIEsMsQDtEVRSRVVGGsLRGAQAAsPAKGEPsLPEKD
P18206 S1101 GPS6|SIGNOR|ELM|EPSD VCL DEESEQATEMLVHNAQNLMQsVKETVREAEAAsIKIRtDAG
P18206 S1113 GPS6|SIGNOR|ELM|EPSD VCL HNAQNLMQsVKETVREAEAAsIKIRtDAGFtLRWVRKTPWy
P18505 S434 ELM GABRB1 YGRALDRHGVPSKGRIRRRAsQLKVKIPDLTDVNSIDKWSR
P18507 S366 ELM|iPTMNet|EPSD GABRG2 VFSALVEYGTLHYFVSNRKPsKDKDKKKKNPLLRMFSFKAP
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P19021 S929 ELM PAM VLGRFRGKGsGGLNLGNFFAsRKGYsRKGFDRLstEGsDQE
P19021 S934 ELM PAM RGKGsGGLNLGNFFAsRKGYsRKGFDRLstEGsDQEKEDDG
P19086 S16 GPS6|SIGNOR|ELM|EPSD|PSP GNAZ _____MGCRQSSEEKEAARRsRRIDRHLRSEsQRQRREIKL
P19086 S27 GPS6|SIGNOR|ELM|EPSD|PSP GNAZ SEEKEAARRsRRIDRHLRSEsQRQRREIKLLLLGTSNSGKS
P19174 S1248 GPS6|SIGNOR|ELM|EPSD|PSP PLCG1 PLC1 LRERGsDASGQLFHGRAREGsFEsRyQQPFEDFRIsQEHLA
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P19429 S166 SIGNOR TNNI3 TNNC1 RVRIsADAMMQALLGARAKEsLDLRAHLKQVKKEDTEKENR
P19429 S199 EPSD|PSP TNNI3 TNNC1 EDTEKENREVGDWRKNIDALsGMEGRKKKFES_________
P19429 S23 SIGNOR|iPTMNet|EPSD|PSP TNNI3 TNNC1 DGSSDAAREPRPAPAPIRRRssNyRAYAtEPHAKKKsKIsA
P19429 S24 SIGNOR|iPTMNet|EPSD|PSP TNNI3 TNNC1 GSSDAAREPRPAPAPIRRRssNyRAYAtEPHAKKKsKIsAs
P19429 S39 SIGNOR TNNI3 TNNC1 IRRRssNyRAYAtEPHAKKKsKIsAsRKLQLKtLLLQIAKQ
P19429 S42 SIGNOR|iPTMNet|EPSD|PSP TNNI3 TNNC1 RssNyRAYAtEPHAKKKsKIsAsRKLQLKtLLLQIAKQELE
P19429 S44 SIGNOR|iPTMNet|EPSD|PSP TNNI3 TNNC1 sNyRAYAtEPHAKKKsKIsAsRKLQLKtLLLQIAKQELERE
P19429 S77 SIGNOR|iPTMNet|EPSD TNNI3 TNNC1 AKQELEREAEERRGEKGRALsTRCQPLELAGLGFAELQDLC
P19429 T143 iPTMNet|EPSD|PSP TNNI3 TNNC1 TEIADLtQKIFDLRGKFKRPtLRRVRIsADAMMQALLGARA
P20020 T1116 iPTMNet|EPSD ATP2B1 PMCA1 AERELRRGQILWFRGLNRIQtQIRVVNAFRSSLYEGLEKPE
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20618 S162 Sugiyama PSMB1 PSC5 DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG
P20700 S396 ELM LMNB1 LMN2 LMNB AYRKLLEGEEERLKLsPsPssRVtVsRAsssRsVRTTRGKR
P20700 S406 ELM LMNB1 LMN2 LMNB ERLKLsPsPssRVtVsRAsssRsVRTTRGKRKRVDVEESEA
P21399 S138 GPS6|ELM|EPSD|PSP ACO1 IREB1 CPADLVIDHSIQVDFNRRADsLQKNQDLEFERNRERFEFLK
P21399 S711 GPS6|SIGNOR|ELM|EPSD|PSP ACO1 IREB1 PAARYLTNRGLTPREFNSYGsRRGNDAVMARGTFANIRLLN
P21730 S314 GPS6|ELM|EPSD|PSP C5AR1 C5AR C5R1 CINPIIYVVAGQGFQGRLRKsLPsLLRNVLTEEsVVREsKs
P21730 S317 GPS6|ELM|EPSD|PSP C5AR1 C5AR C5R1 PIIYVVAGQGFQGRLRKsLPsLLRNVLTEEsVVREsKsFTR
P21730 S327 EPSD|PSP C5AR1 C5AR C5R1 FQGRLRKsLPsLLRNVLTEEsVVREsKsFTRsTVDTMAQKT
P21730 S332 GPS6|ELM|EPSD|PSP C5AR1 C5AR C5R1 RKsLPsLLRNVLTEEsVVREsKsFTRsTVDTMAQKTQAV__
P21730 S334 GPS6|ELM|EPSD|PSP C5AR1 C5AR C5R1 sLPsLLRNVLTEEsVVREsKsFTRsTVDTMAQKTQAV____
P21730 S338 GPS6|ELM|EPSD|PSP C5AR1 C5AR C5R1 LLRNVLTEEsVVREsKsFTRsTVDTMAQKTQAV________
P21731 S145 SIGNOR|PSP TBXA2R AMASERYLGITRPFSRPAVAsQRRAWATVGLVWAAALALGL
P21731 S324 EPSD|PSP TBXA2R DPWVYILFRRAVLRRLQPRLsTRPRsLsLQPQLtQRSGLQ_
P21731 S329 EPSD|PSP TBXA2R ILFRRAVLRRLQPRLsTRPRsLsLQPQLtQRSGLQ______
P21731 S331 EPSD|PSP TBXA2R FRRAVLRRLQPRLsTRPRsLsLQPQLtQRSGLQ________
P21731 T337 EPSD|PSP TBXA2R RRLQPRLsTRPRsLsLQPQLtQRSGLQ______________
P22460 T15 EPSD|PSP KCNA5 ______MEIALVPLENGGAMtVRGGDEARAGCGQATGGELQ
P22626 S212 Sugiyama HNRNPA2B1 HNRPA2B1 EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD
P22681 S619 SIGNOR|iPTMNet|EPSD CBL CBL2 RNF55 PVSAPSSSDPWTGRELtNRHsLPFsLPSQMEPRPDVPRLGs
P22681 S623 SIGNOR|iPTMNet|EPSD CBL CBL2 RNF55 PSSSDPWTGRELtNRHsLPFsLPSQMEPRPDVPRLGstFsL
P22681 S639 SIGNOR|iPTMNet|EPSD CBL CBL2 RNF55 sLPFsLPSQMEPRPDVPRLGstFsLDtsMsMNssPLVGPEC
P22681 S642 SIGNOR|iPTMNet|EPSD CBL CBL2 RNF55 FsLPSQMEPRPDVPRLGstFsLDtsMsMNssPLVGPECDHP
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23396 S104 Sugiyama RPS3 OK/SW-cl.26 VELyAEKVAtRGLCAIAQAEsLRyKLLGGLAVRRACyGVLR
P23528 S23 SIGNOR|EPSD|PSP CFL1 CFL sGVAVsDGVIKVFNDMKVRKsstPEEVKKRKKAVLFCLsED
P23528 S24 SIGNOR|EPSD|PSP CFL1 CFL GVAVsDGVIKVFNDMKVRKsstPEEVKKRKKAVLFCLsEDK
P23588 S207 Sugiyama EIF4B DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR
P23677 T311 ELM|iPTMNet|EPSD ITPKA KMLAVDPEAPTEEEHAQRAVtKPRYMQWREGISSSTTLGFR
P23975 S259 PSP SLC6A2 NAT1 NET1 SLC6A5 LCLMVVVIVLYFSLWKGVKtsGKVVWITATLPYFVLFVLLV
P23975 T258 PSP SLC6A2 NAT1 NET1 SLC6A5 LLCLMVVVIVLYFSLWKGVKtsGKVVWITATLPYFVLFVLL
P24046 S431 iPTMNet|EPSD GABRR1 NYMPENGEKPDRMMVQLTLAsERssPQRKsQRssYVsMRID
P24046 S440 SIGNOR|iPTMNet|EPSD GABRR1 PDRMMVQLTLAsERssPQRKsQRssYVsMRIDTHAIDKYSR
P24046 S443 SIGNOR|iPTMNet|EPSD GABRR1 MMVQLTLAsERssPQRKsQRssYVsMRIDTHAIDKYSRIIF
P24046 S444 SIGNOR|iPTMNet|EPSD GABRR1 MVQLTLAsERssPQRKsQRssYVsMRIDTHAIDKYSRIIFP
P24046 S447 SIGNOR|iPTMNet|EPSD GABRR1 LTLAsERssPQRKsQRssYVsMRIDTHAIDKYSRIIFPAAY
P24534 S141 Sugiyama EEF1B2 EEF1B EF1B ERLAQYESKKAKKPALVAKssILLDVKPWDDEtDMAKLEEC
P24844 S2 SIGNOR|EPSD|PSP MYL9 MLC2 MRLC1 MYRL2 ___________________MssKRAKAKtTKKRPQRAtsNV
P24844 S3 SIGNOR|EPSD|PSP MYL9 MLC2 MRLC1 MYRL2 __________________MssKRAKAKtTKKRPQRAtsNVF
P24844 T10 SIGNOR|EPSD|PSP MYL9 MLC2 MRLC1 MYRL2 ___________MssKRAKAKtTKKRPQRAtsNVFAMFDQSQ
P25098 S29 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP GRK2 ADRBK1 BARK BARK1 ADVSyLMAMEKSKATPAARAsKKILLPEPSIRSVMQKYLED
P25100 S300 PSP ADRA1D ADRA1A VARSTTRSLEAGVKRERGKAsEVVLRIHCRGAATGADGAHG
P25100 S323 PSP ADRA1D ADRA1A VLRIHCRGAATGADGAHGMRsAKGHtFRssLsVRLLKFSRE
P25100 S332 PSP ADRA1D ADRA1A ATGADGAHGMRsAKGHtFRssLsVRLLKFSREKKAAKTLAI
P25100 S334 PSP ADRA1D ADRA1A GADGAHGMRsAKGHtFRssLsVRLLKFSREKKAAKTLAIVV
P25100 S516 PSP ADRA1D ADRA1A EWRLLGPFRRPtTQLRAKVssLsHKIRAGGAQRAEAACAQR
P25100 S518 PSP ADRA1D ADRA1A RLLGPFRRPtTQLRAKVssLsHKIRAGGAQRAEAACAQRSE
P25205 S447 Sugiyama MCM3 EQGRVTIAKAGIHARLNARCsVLAAANPVyGRyDQyKTPME
P25789 T10 Sugiyama PSMA4 HC9 PSC9 ___________MSRRyDsRttIFsPEGRLYQVEYAMEAIGH
P25789 Y5 Sugiyama PSMA4 HC9 PSC9 ________________MSRRyDsRttIFsPEGRLYQVEYAM
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T24 Sugiyama RPL13 BBC1 OK/SW-cl.46 SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27348 S63 Sugiyama YWHAQ LLsVAyKNVVGGRRSAWRVIsSIEQKTDTSDKKLQLIKDYR
P27635 S137 EPSD RPL10 DXS648E QM GAFGKPQGTVARVHIGQVIMsIRTKLQNKEHVIEALRRAKF
P27635 S168 SIGNOR|EPSD RPL10 DXS648E QM VIEALRRAKFKFPGRQKIHIsKKWGFTKFNADEFEDMVAEK
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27824 S583 ELM CANX VsQEEEDRKPKAEEDEILNRsPRNRKPRRE___________
P28329 S464 SIGNOR|EPSD CHAT PFDGIVLVQCTEHLLKHVTQssRKLIRADsVSELPAPRRLR
P28329 S465 SIGNOR|EPSD CHAT FDGIVLVQCTEHLLKHVTQssRKLIRADsVSELPAPRRLRW
P28329 S558 SIGNOR|EPSD CHAT ALQLAFYRLHRRLVPTYESAsIRRFQEGRVDNIRSAtPEAL
P28329 S594 SIGNOR|EPSD CHAT tPEALAFVRAVTDHKAAVPAsEKLLLLKDAIRAQTAYTVMA
P28329 T373 SIGNOR|EPSD CHAT LTSDGRSEWAEARTVLVKDStNRDSLDMIERCICLVCLDAP
P29317 S892 PSP EPHA2 ECK DKLIRAPDSLKTLADFDPRVsIRLPstsGsEGVPFRTVsEW
P29350 S591 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP PTPN6 HCP PTP1C NKREEKVKKQRSADKEKSKGsLKRK________________
P29353 S139 SIGNOR|EPSD SHC1 SHC SHCA GRRTRVEGGQLGGEEWTRHGsFVNKPTRGWLHPNDKVMGPG
P29474 T495 SIGNOR|EPSD|PSP NOS3 YQPDPWKGSAAKGTGITRKKtFKEVANAVKISASLMGTVMA
P29475 S852 iPTMNet|EPSD NOS1 EMRHPNSVQEERKSYKVRFNsVSSYSDsQKSSGDGPDLRDN
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29966 S101 SIGNOR|iPTMNet|EPSD MARCKS MACS PRKCSL sPsAAEKGEPAAAAAPEAGAsPVEKEAPAEGEAAEPGsPtA
P29966 S118 SIGNOR|iPTMNet|EPSD MARCKS MACS PRKCSL AGAsPVEKEAPAEGEAAEPGsPtAAEGEAAsAAsstssPKA
P29966 S159 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP MARCKS MACS PRKCSL EDGAtPsPsNEtPKKKKKRFsFKKsFKLsGFsFKKNKKEAG
P29966 S163 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP MARCKS MACS PRKCSL tPsPsNEtPKKKKKRFsFKKsFKLsGFsFKKNKKEAGEGGE
P29966 S167 ELM|iPTMNet|EPSD|PSP MARCKS MACS PRKCSL sNEtPKKKKKRFsFKKsFKLsGFsFKKNKKEAGEGGEAEAP
P29966 S170 SIGNOR|ELM|iPTMNet|EPSD|PSP MARCKS MACS PRKCSL tPKKKKKRFsFKKsFKLsGFsFKKNKKEAGEGGEAEAPAAE
P29966 S27 iPTMNet|EPSD MARCKS MACS PRKCSL KTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAsP
P29966 S46 SIGNOR|iPTMNet|EPSD MARCKS MACS PRKCSL ssPsKANGQENGHVKVNGDAsPAAAEsGAKEELQANGsAPA
P29966 S81 SIGNOR|iPTMNet|EPSD MARCKS MACS PRKCSL NGsAPAADKEEPAAAGsGAAsPsAAEKGEPAAAAAPEAGAs
P29972 T157 SIGNOR|ELM|EPSD|PSP AQP1 CHIP28 QGLGIEIIGTLQLVLCVLATtDRRRRDLGGSAPLAIGLSVA
P29972 T239 SIGNOR|ELM|EPSD|PSP AQP1 CHIP28 GGALAVLIYDFILAPRSSDLtDRVKVWtsGQVEEyDLDADD
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30086 S153 GPS6|ELM|iPTMNet|EPSD|PSP PEBP1 PBP PEBP CDEPILsNRsGDHRGKFKVAsFRKKyELRAPVAGtCyQAEW
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30411 S373 GPS6|ELM|EPSD|PSP BDKRB2 BKR2 KGGCRSEPIQMENsMGTLRTsIsVERQIHKLQDWAGSRQ__
P30622 S204 Sugiyama CLIP1 CYLN1 RSN PISNLTKtAsEsIsNLsEAGsIKKGERELKIGDRVLVGGTK
P30622 S312 SIGNOR CLIP1 CYLN1 RSN KANAVRRVMATtsAsLKRsPsAssLsSMSSVASSVSSRPSR
P30679 S336 ELM|EPSD GNA15 GNA16 YTRMYTGCVDGPEGsKKGARsRRLFSHYTCATDTQNIRKVF
P31146 T412 PSP CORO1A CORO1 LKDGYVPPKSRELRVNRGLDtGRRRAAPEAsGtPssDAVSR
P31153 S247 Sugiyama MAT2A AMS2 MATA2 IKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLtGRKII
P31431 S179 SIGNOR|iPTMNet|EPSD SDC4 LFAVFLILLLMYRMKKKDEGsyDLGKKPIYKKAPTNEFyA_
P31645 S149 EPSD|PSP SLC6A4 HTT SERT GIPLFYMELALGQyHRNGCIsIWRKICPIFKGIGYAICIIA
P31645 S277 EPSD|PSP SLC6A4 HTT SERT LCIMLIFTVIYFSIWKGVKtsGKVVWVTATFPYIILSVLLV
P31645 T603 EPSD|PSP SLC6A4 HTT SERT TSSFICIPTYIAYRLIITPGtFKERIIKsItPEtPTEIPCG
P31749 S473 EPSD|PSP AKT1 PKB RAC DQDDSMECVDSERRPHFPQFsysAsGtA_____________
P31749 T308 EPSD|PSP AKT1 PKB RAC IKITDFGLCKEGIKDGAtMKtFCGtPEyLAPEVLEDNDyGR
P31751 S474 Sugiyama AKT2 DRyDsLGLLELDQRTHFPQFsysAsIRE_____________
P31751 S476 Sugiyama AKT2 yDsLGLLELDQRTHFPQFsysAsIRE_______________
P31751 S478 Sugiyama AKT2 sLGLLELDQRTHFPQFsysAsIRE_________________
P31751 Y475 Sugiyama AKT2 RyDsLGLLELDQRTHFPQFsysAsIRE______________
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31946 S65 Sugiyama YWHAB LLsVAyKNVVGARRSsWRVIsSIEQKTERNEKKQQMGKEYR
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P32004 T1172 SIGNOR|EPSD|PSP L1CAM CAML1 MIC5 sVKDKEDtQVDsEARPMKDEtFGEyRsLEsDNEEKAFGssQ
P32119 T142 Sugiyama PRDX2 NKEFB TDPX1 EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF
P33316 S120 Sugiyama DUT PsKRARPAEVGGMQLRFARLsEHAtAPTRGsARAAGYDLYS
P33778 S33 EPSD H2BC3 H2BFF HIST1H2BB KGsKKAITKAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDT
P33992 S424 Sugiyama MCM5 CDC46 tsGKGSSAAGLtAsVMRDPssRNFIMEGGAMVLADGGVVCI
P34741 S187 SIGNOR|ELM|iPTMNet|EPSD SDC2 HSPG1 LVYRMRKKDEGsyDLGERKPssAAYQKAPTKEFYA______
P34741 S188 SIGNOR|ELM|iPTMNet|EPSD SDC2 HSPG1 VYRMRKKDEGsyDLGERKPssAAYQKAPTKEFYA_______
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P35221 S641 Sugiyama CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35367 S396 GPS6|ELM|EPSD|PSP HRH1 LRsGsNtGLDYIKFTWKRLRsHsRQYVSGLHMNRERKAAKQ
P35367 S398 GPS6|SIGNOR|ELM|EPSD|PSP HRH1 sGsNtGLDYIKFTWKRLRsHsRQYVSGLHMNRERKAAKQLG
P35367 T478 GPS6|SIGNOR|ELM|EPSD|PSP HRH1 YINSTLNPLIYPLCNENFKKtFKRILHIRS___________
P35368 S396 SIGNOR|iPTMNet|EPSD ADRA1B RRRRRLGGCAYTYRPWTRGGsLERSQsRKDsLDDsGsCLSG
P35368 S402 SIGNOR|iPTMNet|EPSD ADRA1B GGCAYTYRPWTRGGsLERSQsRKDsLDDsGsCLSGSQRTLP
P35368 S406 SIGNOR|iPTMNet|EPSD ADRA1B YTYRPWTRGGsLERSQsRKDsLDDsGsCLSGSQRTLPSASP
P35368 S410 SIGNOR|iPTMNet|EPSD ADRA1B PWTRGGsLERSQsRKDsLDDsGsCLSGSQRTLPSASPSPGY
P35368 S412 SIGNOR|iPTMNet|EPSD ADRA1B TRGGsLERSQsRKDsLDDsGsCLSGSQRTLPSASPSPGYLG
P35398 S100 PSP RORA NR1F1 RZRA SSGIHYGVITCEGCKGFFRRsQQSNATYSCPRQKNCLIDRT
P35398 S35 SIGNOR|EPSD|PSP RORA NR1F1 RZRA PGSSGADAAAGSRETPLNQEsARKSEPPAPVRRQSYSSTSR
P35408 S259 ELM PTGER4 PTGER2 RGHPAAsPALPRLSDFRRRRsFRRIAGAEIQMVILLIATSL
P35408 S354 ELM PTGER4 PTGER2 KTVLSKAIEKIKCLFCRIGGsRRERSGQHCSDSQRTSSAMs
P35408 S430 ELM PTGER4 PTGER2 GGRNLLPGVPGMGLAQEDttsLRtLRISETSDSSQGQDSES
P35408 S460 ELM PTGER4 PTGER2 SDSSQGQDSESVLLVDEAGGsGRAGPAPKGSSLQVTFPSET
P35408 S484 ELM PTGER4 PTGER2 GPAPKGSSLQVTFPSETLNLsEKCI________________
P35408 T433 ELM PTGER4 PTGER2 NLLPGVPGMGLAQEDttsLRtLRISETSDSSQGQDSESVLL
P35503 S43 SIGNOR|PSP UGT1A3 GNT1 UGT1 QPWAESGKVLVVPIDGSHWLsMREVLRELHARGHQAVVLTP
P35568 S24 SIGNOR IRS1 PPEsDGFSDVRKVGYLRKPKsMHKRFFVLRAAsEAGGPARL
P35579 S1916 GPS6|ELM|EPSD|PSP MYH9 LQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMAR
P35611 S5 GPS6|ELM|EPSD ADD1 ADDA ________________MNGDsRAAVVtsPPPttAPHKERyF
P35611 S716 GPS6|ELM|EPSD|PSP ADD1 ADDA AVEEGAAADPGsDGSPGKSPsKKKKKFRtPsFLKKSKKKSD
P35611 S726 GPS6|SIGNOR|ELM|EPSD|PSP ADD1 ADDA GsDGSPGKSPsKKKKKFRtPsFLKKSKKKSDS_________
P35612 S703 GPS6|ELM|EPSD ADD2 ADDB KTESVTSGPMsPEGsPsKsPsKKKKKFRTPsFLKKSKKKEK
P35612 S713 SIGNOR|ELM|EPSD|PSP ADD2 ADDB sPEGsPsKsPsKKKKKFRTPsFLKKSKKKEKVEs_______
P35612 S726 ELM|EPSD|PSP ADD2 ADDB KKKFRTPsFLKKSKKKEKVEs____________________
P35869 S12 GPS6|ELM|EPSD|PSP AHR BHLHE76 _________MNSSSANITYAsRKRRKPVQKTVKPIPAEGIK
P35869 S36 GPS6|ELM|EPSD|PSP AHR BHLHE76 RKPVQKTVKPIPAEGIKSNPsKRHRDRLNTELDRLASLLPF
P35900 S13 EPSD|PSP KRT20 ________MDFSRRSFHRSLsSSLQAPVVSTVGMQRLGTTP
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36542 S146 EPSD|PSP ATP5F1C ATP5C ATP5C1 ATP5CL1 KEVMLVGIGDKIRGILYRtHsDQFLVAFKEVGRKPPTFGDA
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P36871 S483 Sugiyama PGM1 DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR
P36897 T200 EPSD|PSP TGFBR1 ALK5 SKR4 LIyDMttsGsGsGLPLLVQRtIARtIVLQESIGKGRFGEVW
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37231 T166 PSP PPARG NR1C3 ASGFHYGVHACEGCKGFFRRtIRLKLIYDRCDLNCRIHKKS
P37802 S11 EPSD|PSP TAGLN2 KIAA0120 CDABP0035 __________MANRGPAyGLsREVQQKIEKQyDADLEQILI
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 S185 EPSD|PSP|Sugiyama TAGLN2 KIAA0120 CDABP0035 NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______
P37802 T180 EPSD|PSP|Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P38646 S200 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 NyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNVLRVI
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T192 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 MKMKEtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIs
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 Y196 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 EtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNV
P38936 S146 GPS6|ELM|EPSD|PSP CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 QAEGsPGGPGDSQGRKRRQtsMTDFYHsKRRLIFSKRKP__
P38936 S153 SIGNOR|EPSD|PSP CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 GPGDSQGRKRRQtsMTDFYHsKRRLIFSKRKP_________
P38936 T145 GPS6|ELM|EPSD CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 EQAEGsPGGPGDSQGRKRRQtsMTDFYHsKRRLIFSKRKP_
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40818 S719 Sugiyama USP8 KIAA0055 UBPY KPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtPT
P41091 T22 Sugiyama EIF2S3 EIF2G AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
P41091 T66 EPSD|PSP EIF2S3 EIF2G tIGHVAHGKSTVVKAISGVHtVRFKNELERNITIKLGYANA
P41143 S344 SIGNOR|ELM|iPTMNet|EPSD OPRD1 OPRD NFKRCFRQLCRKPCGRPDPSsFSRAREATARERVtACtPsD
P41180 S875 PSP CASR GPRC2A PCAR1 NKIYIILFKPSRNTIEEVRCsTAAHAFKVAARAtLRRsNVs
P41180 T888 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP CASR GPRC2A PCAR1 TIEEVRCsTAAHAFKVAARAtLRRsNVsRKRsssLGGSTGS
P41181 S256 PSP AQP2 VLKGLEPDTDWEEREVRRRQsVELHsPQsLPRGtKA_____
P41594 S840 SIGNOR|iPTMNet|EPSD GRM5 GPRC1E MGLUR5 PKVYIILAKPERNVRSAFTTstVVRMHVGDGKSSSAASRSS
P41594 T841 SIGNOR|iPTMNet|EPSD GRM5 GPRC1E MGLUR5 KVYIILAKPERNVRSAFTTstVVRMHVGDGKSSSAASRSSS
P42261 S832 SIGNOR GRIA1 GLUA1 GLUH1 GLUR1 ILIGGLGLAMLVALIEFCYKsRsEsKRMKGFCLIPQQsINE
P42261 S834 EPSD|PSP GRIA1 GLUA1 GLUH1 GLUR1 IGGLGLAMLVALIEFCYKsRsEsKRMKGFCLIPQQsINEAI
P42261 S836 EPSD|PSP GRIA1 GLUA1 GLUH1 GLUR1 GLGLAMLVALIEFCYKsRsEsKRMKGFCLIPQQsINEAIRT
P42261 S849 GPS6|ELM|iPTMNet|EPSD|PSP GRIA1 GLUA1 GLUH1 GLUR1 CYKsRsEsKRMKGFCLIPQQsINEAIRTStLPRNsGAGASS
P42262 S683 SIGNOR|iPTMNet|EPSD GRIA2 GluA2 GLUR2 QTEIAYGTLDSGSTKEFFRRsKIAVFDKMWTYMRSAEPSVF
P42262 S717 SIGNOR|iPTMNet|EPSD GRIA2 GluA2 GLUR2 SAEPSVFVRTTAEGVARVRKsKGKYAYLLESTMNEYIEQRK
P42262 S880 SIGNOR|iPTMNet|EPSD GRIA2 GluA2 GLUR2 SQNSQNFATYKEGYNVyGIEsVKI_________________
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P43119 S328 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP PTGIR PRIPR CCLCLGPAHGDSQTPLSQLAsGRRDPRAPSAPVGKEGSCVP
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P43629 S415 SIGNOR|EPSD|PSP KIR3DL1 CD158E NKAT3 NKB1 EVTYAQLDHCVFTQRKITRPsQRPKtPPTDTILYTELPNAK
P45379 S189 EPSD|PSP TNNT2 REEEENRRKAEDEARKKKALsNMMHFGGYIQKQAQtERKsG
P46013 S2299 Sugiyama MKI67 MKAFMGtPVQKLDLPGNLPGsKRWPQTPKEKAQALEDLAGF
P46060 S24 Sugiyama RANGAP1 KIAA1835 SD EDIAKLAETLAKTQVAGGQLsFKGKSLKLNTAEDAKDVIKE
P46087 S40 Sugiyama NOP2 NOL1 NSUN1 KQKGAEtELVRFLPAVsDENsKRLsSRARKRAAKRRLGsVE
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46777 T177 Sugiyama RPL5 MSTP030 NKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRK
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46940 S1443 SIGNOR|EPSD|PSP IQGAP1 KIAA0051 AMQRRAIRDAKTPDKMKKsKsVKEDsNLtLQEKKEKIQTGL
P47712 S727 Sugiyama PLA2G4A CPLA2 PLA2G4 VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P48048 S201 SIGNOR|EPSD|PSP KCNJ1 ROMK1 KIsRPKKRAKtItFSKNAVIsKRGGKLCLLIRVANLRKsLL
P48048 S4 SIGNOR|EPSD|PSP KCNJ1 ROMK1 _________________MNAsSRNVFDTLIRVLTESMFKHL
P48048 T193 SIGNOR|PSP KCNJ1 ROMK1 FMCGAILAKIsRPKKRAKtItFSKNAVIsKRGGKLCLLIRV
P48050 T53 SIGNOR|EPSD|PSP KCNJ4 IRK3 ANLSNKSQRYMADIFTTCVDtRWRYMLMIFSAAFLVSWLFF
P48058 S862 SIGNOR|ELM|iPTMNet|EPSD GRIA4 GluA4 GLUR4 AEAKRMKLtFSEAIRNKARLsITGSVGENGRVLTPDCPKAV
P48058 T850 SIGNOR|ELM|iPTMNet|EPSD GRIA4 GluA4 GLUR4 LVALIEFCYKSRAEAKRMKLtFSEAIRNKARLsITGSVGEN
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48730 S181 GPS6|SIGNOR|PSP CSNK1D HCKID tHQHIPYRENKNLtGtARYAsINtHLGIEQsRRDDLESLGY
P48730 S191 PSP CSNK1D HCKID KNLtGtARYAsINtHLGIEQsRRDDLESLGYVLMYFNLGSL
P48730 S298 PSP CSNK1D HCKID HRQGFSYDYVFDWNMLKFGAsRAADDAERERRDREERLRHS
P48730 S53 GPS6|SIGNOR|PSP CSNK1D HCKID EEVAIKLECVKTKHPQLHIEsKIYKMMQGGVGIPTIRWCGA
P48730 T161 PSP CSNK1D HCKID KGNLVyIIDFGLAKKyRDARtHQHIPYRENKNLtGtARYAs
P48730 T174 PSP CSNK1D HCKID KKyRDARtHQHIPYRENKNLtGtARYAsINtHLGIEQsRRD
P48730 T176 GPS6|SIGNOR|PSP CSNK1D HCKID yRDARtHQHIPYRENKNLtGtARYAsINtHLGIEQsRRDDL
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P49407 S163 SIGNOR|PSP ARRB1 ARR1 DYEVKAFCAENLEEKIHKRNsVRLVIRKVQYAPERPGPQPT
P49685 S357 EPSD|PSP GPR15 LTKALstFIHAEDFARRRKRsVsL_________________
P49768 S346 GPS6|SIGNOR|ELM|EPSD PSEN1 AD3 PS1 PSNL1 DtVAENDDGGFsEEWEAQRDsHLGPHRstPEsRAAVQELss
P49795 S24 iPTMNet|EPSD RGS19 GAIP GNAI3IP PHEAEKQITGPEEADRPPsMssHDTASPAAPSRNPCCLCWC
P49795 T201 ELM|iPTMNet|EPSD RGS19 GAIP GNAI3IP QLQIYTLMHRDSYPRFLSSPtYRALLLQGPSQsssEA____
P49802 S434 GPS6|ELM|iPTMNet|EPSD|PSP RGS7 PGRYTFEDAQEHIYKLMKSDsYPRFIRSSAYQELLQAKKKS
P49840 S21 SIGNOR|ELM|iPTMNet|EPSD|PSP GSK3A MsGGGPsGGGPGGsGRARtssFAEPGGGGGGGGGGPGGsAs
P49841 S9 SIGNOR|EPSD|PSP GSK3B ____________MSGRPRttsFAEsCKPVQQPsAFGsMKVS
P50552 S157 GPS6|EPSD|PSP VASP EVEQQKRQQPGPSEHIERRVsNAGGPPAPPAGGPPPPPGPP
P51116 S601 Sugiyama FXR2 FMR1L2 RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ
P51674 T10 GPS6|SIGNOR|ELM|iPTMNet|EPSD GPM6A M6A ___________MEENMEEGQtQKGCFECCIKCLGGIPYASL
P51811 S63 ELM XK XKR1 XRG1 FSLLPCALVQLTLLFVHRDLsRDRPLVLLLHLLQLGPLFRC
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P52565 S34 EPSD|PSP ARHGDIA GDIA1 IAAENEEDEHsVNyKPPAQKsIQEIQELDKDDEsLRKyKEA
P52565 S96 EPSD|PSP ARHGDIA GDIA1 TLVCSSAPGPLELDLtGDLEsFKKQsFVLKEGVEYRIKISF
P52566 S31 SIGNOR|EPSD|PSP ARHGDIB GDIA2 GDID4 RAP1GN1 EEDDDDELDsKLNyKPPPQKsLKELQEMDKDDEsLIKYKKT
P53004 S149 EPSD BLVRA BLVR BVR LMEEFAFLKKEVVGKDLLKGsLLFTAGPLEEERFGFPAFSG
P53004 S230 EPSD BLVRA BLVR BVR KsPLSWIEEKGPGLKRNRyLsFHFKsGsLENVPNVGVNKNI
P53396 S455 Sugiyama ACLY ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P55042 S214 SIGNOR|iPTMNet|EPSD|PSP RRAD RAD DDVPIILVGNKSDLVRSREVsVDEGRACAVVFDCKFIETSA
P55042 S257 SIGNOR|iPTMNet|EPSD|PSP RRAD RAD HHNVQALFEGVVRQIRLRRDsKEANARRQAGTRRREsLGKK
P55042 S273 SIGNOR|EPSD|PSP RRAD RAD LRRDsKEANARRQAGTRRREsLGKKAKRFLGRIVARNsRKM
P55042 S290 SIGNOR|iPTMNet|EPSD|PSP RRAD RAD RREsLGKKAKRFLGRIVARNsRKMAFRAKsKsCHDLSVL__
P55042 S299 SIGNOR|iPTMNet|EPSD|PSP RRAD RAD KRFLGRIVARNsRKMAFRAKsKsCHDLSVL___________
P55087 S180 SIGNOR|EPSD|PSP AQP4 LLVELIITFQLVFTIFASCDsKRTDVTGSIALAIGFSVAIG
P55209 T269 Sugiyama NAP1L1 NRP GPEIMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVT
P55209 T272 Sugiyama NAP1L1 NRP IMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVTKTV
P55273 S76 SIGNOR CDKN2D IALELLKQGAsPNVQDTSGTsPVHDAARTGFLDTLKVLVEH
P55273 T141 SIGNOR CDKN2D AVVSFLAAESDLHRRDARGLtPLELALQRGAQDLVDILQGH
P56537 S235 GPS6|SIGNOR|ELM|EPSD|PSP EIF6 EIF3A ITGB4BP OK/SW-cl.27 LSVVESVFKLNEAQPstIAtsMRDsLIDsLt__________
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60880 S187 SIGNOR|iPTMNet|EPSD|PSP SNAP25 SNAP MGNEIDTQNRQIDRIMEKADsNKTRIDEANQRATKMLGSG_
P60880 T138 SIGNOR|iPTMNet|EPSD|PSP SNAP25 SNAP ARVVDEREQMAISGGFIRRVtNDARENEMDENLEQVsGIIG
P60983 S53 SIGNOR GMFB IMKIDKDKRLVVLDEELEGIsPDELKDELPERQPRFIVYsY
P60983 S72 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP GMFB IsPDELKDELPERQPRFIVYsYKYQHDDGRVsYPLCFIFSS
P60983 T27 SIGNOR GMFB VCDVAEDLVEKLRKFRFRKEtNNAAIIMKIDKDKRLVVLDE
P61081 S175 Sugiyama UBE2M UBC12 NNRRLFEQNVQRSMRGGyIGstyFERCLK____________
P61221 S186 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 AIIKPQYVDQIPKAAKGtVGsILDRKDETKTQAIVCQQLDL
P61254 S9 Sugiyama RPL26 ____________MKFNPFVtsDRsKNRKRHFNAPsHIRRKI
P61353 S86 Sugiyama RPL27 SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL
P61353 T94 Sugiyama RPL27 VyNyNHLMPtRysVDIPLDKtVVNKDVFRDPALKRKARREA
P61513 S21 Sugiyama RPL37A MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQHAKYTCSF
P61513 Y14 Sugiyama RPL37A _______MAKRTKKVGIVGKyGtRYGAsLRKMVKKIEISQH
P61764 S306 SIGNOR|iPTMNet|EPSD STXBP1 UNC18A DLWIALRHKHIAEVSQEVTRsLKDFSSsKRMNTGEKTTMRD
P61764 S313 iPTMNet|EPSD STXBP1 UNC18A HKHIAEVSQEVTRsLKDFSSsKRMNTGEKTTMRDLSQMLKK
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981 S64 Sugiyama YWHAG LLsVAyKNVVGARRSsWRVIsSIEQKtsADGNEKKIEMVRA
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 S67 Sugiyama RPS11 PKEAIEGtyIDKKCPFTGNVsIRGRILsGVVTKMKMQRTIV
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62491 S177 SIGNOR RAB11A RAB11 DSTNVEAAFQTILTEIYRIVsQKQMSDRRENDMsPsNNVVP
P62701 T247 Sugiyama RPS4X CCG2 RPS4 SCAR VIGKGNKPWIsLPRGKGIRLtIAEERDKRLAAKQSSG____
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62857 S39 Sugiyama RPS28 GRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLL
P62899 S15 Sugiyama RPL31 ______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62906 S64 Sugiyama RPL10A NEDD6 QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 S51 Sugiyama PPIA CYPA KtAENFRALSTGEKGFGYKGsCFHRIIPGFMCQGGDFtRHN
P62937 T157 Sugiyama PPIA CYPA NIVEAMERFGsRNGKTSKKItIADCGQLE____________
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 S134 Sugiyama RPS27A UBA80 UBCEP1 IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T432 ELM|Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P68431 T7 EPSD H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ______________MARtKQtARKstGGKAPRKQLATKAAR
P78314 S225 GPS6|ELM|EPSD SH3BP2 3BP2 RES4-23 PPPPVPTPRKPAFSDMPRAHsFTSKGPGPLLPPPPPKHGLP
P78345 S253 Sugiyama RPP38 DtsFEDLsKPKRKLADGRQAsVtLQPLKIKKLIPNPNKIRK
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P78417 S23 Sugiyama GSTO1 GSTTLP28 GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK
P78536 T735 EPSD|PSP ADAM17 CSVP TACE MLSSMDSASVRIIKPFPAPQtPGRLQPAPVIPSAPAAPKLD
P81274 S408 EPSD|PSP GPSM2 LGN ENTEIDSSLNGVRPKLGRRHsMENMELMKLtPEKVQNWNSE
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S7 Sugiyama RPL24 ______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 S9 Sugiyama RPL24 ____________MKVELCsFsGyKIYPGHGRRYARTDGKVF
P83731 T52 Sugiyama RPL24 LNAKCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRT
P84098 S12 Sugiyama RPL19 _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098 S13 Sugiyama RPL19 ________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEIA
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P98082 S24 ELM DAB2 DOC2 EVEtSATNGQPDQQAAPKAPsKKEKKKGPEKTDEyLLARFK
Q00169 S165 GPS6|ELM|EPSD PITPNA PITPN DRSQVLSKDYKAEEDPAKFKsIKTGRGPLGPNWKQELVNQK
Q00341 S904 Sugiyama HDLBP HBP VGL FHRSVMGPKGSRIQQITRDFsVQIKFPDREENAVHSTEPVV
Q00613 S307 GPS6 HSF1 HSTF1 RPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDtLLsP
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q01814 T1139 iPTMNet|EPSD ATP2B2 PMCA2 AERELRRGQILWFRGLNRIQtQIRVVKAFRssLyEGLEKPE
Q01826 S185 PSP SATB1 TLKIQLHSCPKLEDLPPEQWsHTtVRNALKDLLKDMNQSSL
Q01844 S266 SIGNOR|ELM|iPTMNet|EPSD|PSP EWSR1 EWS SYSQAPSQYSQQSSSYGQQSsFRQDHPssMGVyGQESGGFS
Q01954 S541 GPS6|ELM|EPSD|PSP BNC1 BNC QLISNEMPFDALPKKKsRKSsMPIKIEKEAVEIANEKRHNL
Q01959 S12 EPSD|PSP SLC6A3 DAT1 _________MsKsKCsVGLMssVVAPAKEPNAVGPKEVELI
Q01959 S7 EPSD|PSP SLC6A3 DAT1 ______________MsKsKCsVGLMssVVAPAKEPNAVGPK
Q01970 S1105 SIGNOR|EPSD|PSP PLCB3 EMNEREKKELQKILDRKRHNsIsEAKMRDKHKKEAELTEIN
Q01995 S181 ELM|EPSD|PSP TAGLN SM22 WS3-10 REFtEsQLQEGKHVIGLQMGsNRGAsQAGMTGYGRPRQIIS
Q02156 S234 EPSD|PSP PRKCE PKCE ELIITKCAGLKKQEtPDQVGsQRFsVNMPHKFGIHNYKVPT
Q02156 S316 EPSD|PSP PRKCE PKCE ARGIAKVLADLGVtPDKItNsGQRRKKLIAGAEsPQPAsGs
Q02156 S368 EPSD|PSP PRKCE PKCE PtsPCDQEIKELENNIRKALsFDNRGEEHRAAssPDGQLMs
Q02543 S123 Sugiyama RPL18A AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK
Q03721 S15 GPS6|ELM|EPSD|PSP KCNC4 C1orf30 ______MISSVCVssYRGRKsGNKPPsKTCLKEEMAKGEAS
Q03721 S21 GPS6|ELM|EPSD|PSP KCNC4 C1orf30 MISSVCVssYRGRKsGNKPPsKTCLKEEMAKGEASEKIIIN
Q03721 S8 GPS6|ELM|EPSD KCNC4 C1orf30 _____________MISSVCVssYRGRKsGNKPPsKTCLKEE
Q03721 S9 GPS6|ELM|EPSD KCNC4 C1orf30 ____________MISSVCVssYRGRKsGNKPPsKTCLKEEM
Q04206 S536 EPSD|PSP RELA NFKB3 APLGAPGLPNGLLsGDEDFSsIADMDFsALLSQISS_____
Q04637 S1185 GPS6|SIGNOR|EPSD|PSP EIF4G1 EIF4F EIF4G EIF4GI ERGGDRGDRLDRARTPATKRsFsKEVEERsRERPsQPEGLR
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q04917 S64 Sugiyama YWHAH YWHA1 LLsVAyKNVVGARRSsWRVIsSIEQKTMADGNEKKLEKVKA
Q05193 S778 EPSD|PSP DNM1 DNM VDDSWLQVQSVPAGRRsPTSsPtPQRRAPAVPPARPGsRGP
Q05193 S795 SIGNOR|iPTMNet|EPSD DNM1 DNM PTSsPtPQRRAPAVPPARPGsRGPAPGPPPAGSALGGAPPV
Q05209 S39 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP PTPN12 sPDHNGEDNFARDFMRLRRLsTKYRTEKIyPTATGEKEENV
Q05209 S435 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP PTPN12 LPGKNESTIEQIDKKLERNLsFEIKKVPLQEGPKsFDGNtL
Q05586 S889 ELM GRIN1 NMDAR1 RAEPDPKKKATFRAITSTLAssFKRRRssKDTSTGGGRGAL
Q05586 S890 ELM GRIN1 NMDAR1 AEPDPKKKATFRAITSTLAssFKRRRssKDTSTGGGRGALQ
Q05586 S896 SIGNOR|ELM GRIN1 NMDAR1 KKATFRAITSTLAssFKRRRssKDTSTGGGRGALQNQKDTV
Q05586 S897 ELM GRIN1 NMDAR1 KATFRAITSTLAssFKRRRssKDTSTGGGRGALQNQKDTVL
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q05682 S643 SIGNOR CALD1 CAD CDM PEDGLsDDKKPFKCFTPKGSsLKIEERAEFLNKsVQKsSGV
Q05682 S656 SIGNOR CALD1 CAD CDM CFTPKGSsLKIEERAEFLNKsVQKsSGVKSTHQAAIVSKID
Q05682 S677 SIGNOR CALD1 CAD CDM VQKsSGVKSTHQAAIVSKIDsRLEQyTSAIEGTKsAKPTKP
Q05940 S15 EPSD|PSP SLC18A2 SVMT VMAT2 ______MALSELALVRWLQEsRRsRKLILFIVFLALLLDNM
Q05940 S18 EPSD|PSP SLC18A2 SVMT VMAT2 ___MALSELALVRWLQEsRRsRKLILFIVFLALLLDNMLLT
Q06124 S576 PSP PTPN11 PTP2C SHPTP2 DQSPLPPCTPTPPCAEMREDsARVyENVGLMQQQKsFR___
Q06124 S591 PSP PTPN11 PTP2C SHPTP2 EMREDsARVyENVGLMQQQKsFR__________________
Q06210 S205 SIGNOR|iPTMNet|EPSD GFPT1 GFAT GFPT FALVFKSVHFPGQAVGTRRGsPLLIGVRSEHKLSTDHIPIL
Q06210 S235 iPTMNet|EPSD GFPT1 GFAT GFPT HKLSTDHIPILYRTARTQIGsKFTRWGsQGERGKDKKGSCN
Q06481 T723 SIGNOR|ELM|iPTMNet|EPSD|PSP APLP2 APPL2 VAIATVIVISLVMLRKRQYGtISHGIVEVDPMLtPEERHLN
Q06830 T143 Sugiyama PRDX1 PAGA PAGB TDPX2 EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q07617 S317 iPTMNet|EPSD SPAG1 EDLSKVLDVEPDNDLAKKTLsEVERDLKNsEAASETQTKGK
Q07617 S326 SIGNOR SPAG1 EPDNDLAKKTLsEVERDLKNsEAASETQTKGKRMVIQEIEN
Q07866 S524 Sugiyama KLC1 KLC KNS2 QRVAEVLNDPENMEKRRsREsLNVDVVKYESGPDGGEEVSM
Q07869 S179 GPS6|EPSD|PSP PPARA NR1C1 PPAR HKCLSVGMSHNAIRFGRMPRsEKAKLKAEILTCEHDIEDSE
Q07869 S230 GPS6|EPSD|PSP PPARA NR1C1 PPAR IYEAYLKNFNMNKVKARVILsGKASNNPPFVIHDMETLCMA
Q07954 S4517 SIGNOR|EPSD|PSP LRP1 A2MR APR DKPTNFTNPVyATLYMGGHGsRHsLAsTDEKRELLGRGPED
Q07954 S4520 SIGNOR|EPSD|PSP LRP1 A2MR APR TNFTNPVyATLYMGGHGsRHsLAsTDEKRELLGRGPEDEIG
Q07954 S4523 SIGNOR|EPSD|PSP LRP1 A2MR APR TNPVyATLYMGGHGsRHsLAsTDEKRELLGRGPEDEIGDPL
Q07954 T4460 SIGNOR|EPSD|PSP LRP1 A2MR APR VVFWYKRRVQGAKGFQHQRMtNGAMNVEIGNPTyKMYEGGE
Q09472 S89 GPS6|ELM|EPSD|PSP EP300 P300 GMVQDAASKHKQLSELLRsGssPNLNMGVGGPGQVMAsQAQ
Q12791 S1200 SIGNOR|EPSD|PSP KCNMA1 KCNMA SLO HNAGQSRASLSHSSHSSQSSsKKsssVHSIPSTANRQNRPK
Q12809 S890 EPSD KCNH2 ERG ERG1 HERG GSPGSTELEGGFSRQRKRKLsFRRRtDKDTEQPGEVSALGP
Q12879 S1416 SIGNOR|iPTMNet GRIN2A NMDAR2A VNDSYLRSSLRSTASYCSRDsRGHNDVyISEHVMPYAANKN
Q12879 S929 PSP GRIN2A NMDAR2A NMNSSRMDSPKRAADFIQRGsLIMDMVSDKGNLMySDNRSF
Q12959 T657 EPSD|PSP DLG1 EVGVIPSKRRVEKKERARLKtVKFNSKTRDKGEIPDDMGSK
Q13002 S868 EPSD|PSP GRIK2 GLUR6 KNAQLEKRSFCSAMVEELRMsLKCQRRLKHKPQAPVIVKTE
Q13131 S496 SIGNOR|EPSD|PSP PRKAA1 AMPK1 sIDDEItEAKsGtAtPQRsGsVsNYRSCQRsDsDAEAQGKs
Q13224 S1303 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP GRIN2B NMDAR2B QSPTNSKAQKKNRNKLRRQHsYDTFVDLQKEEAALAPRSVs
Q13224 S1323 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP GRIN2B NMDAR2B sYDTFVDLQKEEAALAPRSVsLKDKGRFMDGSPyAHMFEMS
Q13224 S1415 PSP GRIN2B NMDAR2B QCLLHGSKSYFFRQPTVAGAsKARPDFRALVTNKPVVSALH
Q13247 S297 Sugiyama SRSF6 SFRS6 SRP55 RSRSPKENGKGDIKsKSRsRsQsRsNsPLPVPPsKARsVsP
Q13255 T695 SIGNOR|ELM|EPSD GRM1 GPRC1A MGLUR1 LVTKTNRIARILAGSKKKICtRKPRFMSAWAQVIIASILIS
Q13303 S266 EPSD|PSP KCNAB2 KCNA2B KCNK2 LACGIVSGKYDSGIPPYSRAsLKGyQWLKDKILSEEGRRQQ
Q13393 S2 SIGNOR|iPTMNet|EPSD PLD1 ___________________MsLKNEPRVNTSALQKIAADMs
Q13393 S561 SIGNOR|iPTMNet|EPSD PLD1 IDDVDSKLKGIGKPRKFSKFsLYKQLHRHHLHDADSISSID
Q13393 T147 SIGNOR|iPTMNet|EPSD PLD1 HRELLKYKAFIRIPIPTRRHtFRRQNVREEPREMPSLPRSS
Q13418 T173 EPSD|PSP ILK ILK1 ILK2 EKMGQNLNRIPYKDTFWKGttRTRPRNGtLNKHsGIDFKQL
Q13418 T181 EPSD|PSP ILK ILK1 ILK2 RIPYKDTFWKGttRTRPRNGtLNKHsGIDFKQLNFLTKLNE
Q13507 S785 PSP TRPC3 TRP3 LWLSYFDDGKTLPPPFsLVPsPKSFVYFIMRIVNFPKCRRR
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13522 S67 EPSD|PSP PPP1R1A IPP1 sPEIDEDRIPNPHLKSTLAMsPRQRKKMtRITPTMKELQMM
Q13522 T75 GPS6|EPSD|PSP PPP1R1A IPP1 IPNPHLKSTLAMsPRQRKKMtRITPTMKELQMMVEHHLGQQ
Q13574 S265 SIGNOR DGKZ DAGK6 ILRARRPQNTLKASKKKKRAsFKRKSSKKGPEEGRWRPFII
Q13769 S5 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP THOC5 C22orf19 KIAA0983 ________________MSSEssKKRKPKVIRsDGAPAEGKR
Q13769 S6 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP THOC5 C22orf19 KIAA0983 _______________MSSEssKKRKPKVIRsDGAPAEGKRN
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13887 S153 ELM KLF5 BTEB2 CKLF IKLF SINMNVFLPDITHLRTGLYKsQRPCVTHIKTEPVAIFSHQS
Q13976 T59 GPS6|SIGNOR|ELM|EPSD|PSP PRKG1 PRKG1B PRKGR1A PRKGR1B KLHKCQSVLPVPsTHIGPRTtRAQGIsAEPQTYRsFHDLRQ
Q14011 S159 Sugiyama CIRBP A18HNRNP CIRP RDyySSRsQsGGYSDRssGGsyRDsyDsyATHNE_______
Q14151 S827 Sugiyama SAFB2 KIAA0138 HGGPPERHGRDsRDGWGGyGsDKRLsEGRGLPPPPRGGRDW
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S492 Sugiyama EIF3A EIF3S10 KIAA0139 VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14152 S988 Sugiyama EIF3A EIF3S10 KIAA0139 PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN
Q14315 S2236 SIGNOR FLNC ABPL FLN2 DPFPAVFGDFLGRERLGsFGsITRQQEGEAsSQDMTAQVTs
Q14315 S2623 PSP FLNC ABPL FLN2 LHETSTVLVEtVTKSSssRGssyssIPKFsSDASKVVTRGP
Q14315 S2624 PSP FLNC ABPL FLN2 HETSTVLVEtVTKSSssRGssyssIPKFsSDASKVVTRGPG
Q14432 S292 EPSD|PSP PDE3A GsQLIAGTKEDIPVFKRRRRsssVVsAEMSGCSSKSHRRts
Q14432 S293 EPSD|PSP PDE3A sQLIAGTKEDIPVFKRRRRsssVVsAEMSGCSSKSHRRtsL
Q14432 S312 GPS6|SIGNOR|EPSD|PSP PDE3A sssVVsAEMSGCSSKSHRRtsLPCIPREQLMGHSEWDHKRG
Q14432 S428 GPS6|SIGNOR|EPSD|PSP PDE3A sDsEESSEKDKLAIPKRLRRsLPPGLLRRVsstWttttsAT
Q14432 S438 GPS6|SIGNOR|EPSD|PSP PDE3A KLAIPKRLRRsLPPGLLRRVsstWttttsATGLPTLEPAPV
Q14432 S465 GPS6|SIGNOR|EPSD|PSP PDE3A tsATGLPTLEPAPVRRDRSTsIKLQEAPsssPDsWNNPVMM
Q14432 S492 SIGNOR|EPSD|PSP PDE3A PsssPDsWNNPVMMtLTKsRsFtssyAISAANHVKAKKQSR
Q14432 T568 GPS6 PDE3A PEsADTTAKQSLGSHRALtYtQsAPDLsPQILtPPVICSSC
Q14469 S37 SIGNOR|ELM|iPTMNet|EPSD HES1 BHLHB39 HL HRY tPAsVNttPDKPKTASEHRKssKPIMEKRRRARINESLSQL
Q14469 S38 SIGNOR|ELM|iPTMNet|EPSD HES1 BHLHB39 HL HRY PAsVNttPDKPKTASEHRKssKPIMEKRRRARINESLSQLK
Q14524 S1503 PSP SCN5A QDIFMTEEQKKyyNAMKKLGsKKPQKPIPRPLNKYQGFIFD
Q14749 S10 PSP GNMT ___________MVDSVYRtRsLGVAAEGLPDQYADGEAARV
Q14994 T38 EPSD|PSP NR1I3 CAR ATGYHFNALTCEGCKGFFRRtVSKSIGPTCPFAGSCEVSKT
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15021 S1310 Sugiyama NCAPD2 CAPD2 CNAP1 KIAA0159 RACHTRGLDGIKELEIGQAGsQRAPsAKKPSTGSRyQPLAs
Q15052 S640 SIGNOR ARHGEF6 COOL2 KIAA0006 PIXA sKsPKTMKKFLHKRKTERKPsEEEyVIRKstAALEEDAQIL
Q15052 S684 SIGNOR ARHGEF6 COOL2 KIAA0006 PIXA EAYCTSANFQQGHGsstRKDsIPQVLLPEEEKLIIEETRsN
Q15056 S66 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 VGNLPFNTVQGDIDAIFKDLsIRsVRLVRDKDTDKFKGFCy
Q15056 S69 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 LPFNTVQGDIDAIFKDLsIRsVRLVRDKDTDKFKGFCyVEF
Q15080 S315 GPS6|ELM|EPSD|PSP NCF4 SH3PXD4 VRLLSDEDVALMVRQARGLPsQKRLFPWKLHITQKDNYRVY
Q15080 T154 GPS6|SIGNOR|ELM|EPSD|PSP NCF4 SH3PXD4 YQSPYDSEQVPQALRRLRPRtRKVKsVsPQGNsVDRMAAPR
Q15121 S104 SIGNOR|ELM|iPTMNet|EPSD PEA15 TRVLKIsEEDELDtKLtRIPsAKKYKDIIRQPsEEEIIKLA
Q15139 S249 ELM PRKD1 PKD PKD1 PRKCM EPLLQKsPsEsFIGREKRsNsQsyIGRPIHLDKILMSKVKV
Q15139 S412 PSP PRKD1 PKD PKD1 PRKCM ANRtIsPstsNNIPLMRVVQsVKHTKRKSsTVMKEGWMVHy
Q15139 S738 GPS6|SIGNOR|ELM|EPSD|PSP PRKD1 PKD PKD1 PRKCM DPFPQVKLCDFGFARIIGEKsFRRsVVGtPAyLAPEVLRNK
Q15139 S742 GPS6|SIGNOR|ELM|EPSD|PSP PRKD1 PKD PKD1 PRKCM QVKLCDFGFARIIGEKsFRRsVVGtPAyLAPEVLRNKGYNR
Q15172 S41 SIGNOR|EPSD|PSP PPP2R5A VDGFTRKsVRKAQRQKRsQGssQFRsQGsQAELHPLPQLKD
Q15185 S113 Sugiyama PTGES3 P23 TEBP RAKLNWLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGD
Q15185 S72 Sugiyama PTGES3 P23 TEBP EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15311 S118 EPSD|PSP RALBP1 RLIP RLIP1 RLIP76 EsPSKMKRSKGIHVFKKPsFsKKKEKDFKIKEKPKEEKHKE
Q15311 S353 EPSD|PSP RALBP1 RLIP RLIP1 RLIP76 LETKMNIQNISIVLSPTVQIsNRVLYVFFTHVQELFGNVVL
Q15311 S509 EPSD|PSP RALBP1 RLIP RLIP1 RLIP76 ILTEQEELLAMEQFLRRQIAsEKEEIERLRAEIAEIQSRQQ
Q15311 T297 SIGNOR|iPTMNet|EPSD|PSP RALBP1 RLIP RLIP1 RLIP76 NLLTKELMPRFEEACGRTTEtEKVQEFQRLLKELPECNYLL
Q15417 S259 Sugiyama CNN3 DNSTISLQMGTNKVAsQKGMsVyGLGRQVYDPKYCAAPTEP
Q15424 S803 Sugiyama SAFB HAP HET SAFB1 RHGGPERHGRDsRDGWGGyGsDKRMsEGRGLPPPPRRDWGD
Q15438 S394 ELM CYTH1 D17S811E PSCD1 AAISRDPFYEMLAARKKKVSstKRH________________
Q15438 T395 ELM CYTH1 D17S811E PSCD1 AISRDPFYEMLAARKKKVSstKRH_________________
Q15672 S144 SIGNOR|PSP TWIST1 BHLHA38 TWIST LNEAFAALRKIIPTLPSDKLsKIQTLKLAARYIDFLYQVLQ
Q15717 S158 EPSD|PSP ELAVL1 HUR LVDQTTGLSRGVAFIRFDKRsEAEEAITSFNGHKPPGSSEP
Q15717 S221 EPSD|PSP ELAVL1 HUR HsPARRFGGPVHHQAQRFRFsPMGVDHMSGLSGVNVPGNAS
Q15717 S318 EPSD|PSP ELAVL1 HUR AAMAIAsLNGYRLGDKILQVsFKTNKSHK____________
Q15762 S329 GPS6|ELM|EPSD|PSP CD226 DNAM1 PtNQsMDDTREDIyVNyPtFsRRPKTRV_____________
Q15906 S132 ELM VPS72 TCFL1 YL1 REEKALLPLELQDDGsDsRKsMRQStAEHTRQTFLRVQERQ
Q16236 S40 SIGNOR|ELM NFE2L2 NRF2 IDILWRQDIDLGVSREVFDFsQRRKEYELEKQKKLEKERQE
Q16625 S340 SIGNOR|ELM|iPTMNet|EPSD OCLN DsPMAYSsNGKVNDKRFYPEssyKstPVPEVVQELPLtsPV
Q16629 S183 Sugiyama SRSF7 SFRS7 sRSISLRRSRSASLRRSRSGsIKGsRyFQsPsRsRsRSRSI
Q16629 S187 Sugiyama SRSF7 SFRS7 SLRRSRSASLRRSRSGsIKGsRyFQsPsRsRsRSRSISRPR
Q16637 S31 Sugiyama SMN1 SMN SMNT; SMN2 SMNC GVPEQEDsVLFRRGtGQsDDsDIWDDtALIKAYDKAVAsFK
Q16658 S39 ELM|EPSD|PSP FSCN1 FAN1 HSN SNL CGNKyLTAEAFGFKVNASAssLKKKQIWTLEQPPDEAGSAA
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q16760 S66 GPS6|SIGNOR|ELM|EPSD DGKD KIAA0145 SGQIRQKTIIKEGMLTKQNNsFQRsKRRYFKLRGRTLYYAK
Q16760 S70 GPS6|SIGNOR|ELM|EPSD DGKD KIAA0145 RQKTIIKEGMLTKQNNsFQRsKRRYFKLRGRTLYYAKTAKS
Q16820 S687 SIGNOR|ELM MEP1B MLIITLVSVYCTRKKYRERMsSNRPNLTPQNQHAF______
Q16875 S461 EPSD|PSP PFKFB3 THRERSEDAKKGPNPLMRRNsVtPLAsPEPtKKPRINsFEE
Q2VIR3 T22 Sugiyama EIF2S3B AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
Q32P51 S95 Sugiyama HNRNPA1L2 HNRNPA1L TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
Q38SD2 S1064 SIGNOR|PSP LRRK1 KIAA1790 LQLFENKKNTKSRNRKVTIYsFTGNQRNRCstFRVKRNQTI
Q38SD2 S1074 SIGNOR|PSP LRRK1 KIAA1790 KSRNRKVTIYsFTGNQRNRCstFRVKRNQTIYWQEGLLVTF
Q38SD2 T1075 SIGNOR|PSP LRRK1 KIAA1790 SRNRKVTIYsFTGNQRNRCstFRVKRNQTIYWQEGLLVTFD
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q4G0X9 S553 Sugiyama CCDC40 KIAA1640 EIEAYKKSIMKEEEKNEKLAsILNRTETEATLLQKLTTQCL
Q53EL6 S49 Sugiyama PDCD4 H731 ENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNssR
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF8 S258 Sugiyama HSP90AB2P HSP90BB LAVRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQ
Q5JVS0 T354 SIGNOR|iPTMNet|EPSD|PSP HABP4 MVKDDYEDDSHVFRKPANDItSQLEINFGNLPRPGRGARGG
Q5JVS0 T375 SIGNOR|iPTMNet|EPSD|PSP HABP4 SQLEINFGNLPRPGRGARGGtRGGRGRIRRAENYGPRAEVV
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5VV41 S208 Sugiyama ARHGEF16 EPHEXIN4 NBR HtRsPAKNKKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQ
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q68EM7 S702 SIGNOR ARHGAP17 RICH1 MSTP066 MSTP110 tGQPPGQPSAPSQLSAPRRysssLsPIQAPNHPPPQPPTQA
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UVK1 T2252 SIGNOR CSPG4 MCSP VLLLLALILPLLFYLRKRNKtGKHDVQVLtAKPRNGLAGDT
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q6ZN44 S352 SIGNOR UNC5A KIAA1976 UNC5H1 EGLDSDVADSSILTSGFQPVsIKPSKADNPHLLTIQPDLST
Q6ZN44 S532 SIGNOR UNC5A KIAA1976 UNC5H1 LTRPVILAMDHCGEPSPDSWsLRLKKQSCEGSWEDVLHLGE
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36 S165 PSP TUBA1A TUBA3 TGSGFTSLLMERLsVDYGKKsKLEFSIYPAPQVSTAVVEPY
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7KZI7 T596 GPS6|ELM|EPSD MARK2 EMK1 sssGGAPDRTNFPRGVssRstFHAGQLRQVRDQQNLPyGVt
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z417 S652 Sugiyama NUFIP2 KIAA1321 PIG1 NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86UR1 S172 SIGNOR|EPSD|PSP NOXA1 P51NOX WPEGSLNGLDSALDQVQRRGsLPPRQVPRGEVFRPHRWHLK
Q86UX7 S484 SIGNOR|PSP FERMT3 KIND3 MIG2B URP2 SSYTSEVQAILAFLsLQRtGsGGPGNHPHGPDAsAEGLNPy
Q86VB7 S1084 SIGNOR|EPSD CD163 M130 IFVALFFLtKKRRQRQRLAVsSRGENLVHQIQYREMNSCLN
Q86VB7 T1072 EPSD CD163 M130 IAVGILGVVLLAIFVALFFLtKKRRQRQRLAVsSRGENLVH
Q86VQ1 S223 Sugiyama GLCCI1 QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IWX8 S904 Sugiyama CHERP DAN26 SCAF6 KGVGVALDDPyENyRRNKsysFIARMKARDECK________
Q8N0W4 T707 EPSD|PSP NLGN4X KIAA1260 NLGN4 UNQ365/PRO701 FLNILAFAALYYKKDKRRHEtHRRPSPQRNTTNDIAHIQNE
Q8N556 S277 EPSD|PSP AFAP1 AFAP SECPPPPssPVHKAELEKKLssERPssDGEGVVENGITTCN
Q8N5J4 Y191 PSP SPIC RALRNYGRSGEITKIRRKLTyQFSEAILQRLSPSYFLGKEI
Q8N726 T8 EPSD|PSP CDKN2A CDKN2 MLM _____________MVRRFLVtLRIRRACGPPRVRVFVVHIP
Q8NAF0 S455 Sugiyama ZNF579 AGGPAPHPCPRCPRRFSRAYsLLRHQRCHRAELERAAALQA
Q8NBJ7 S256 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG
Q8NER1 S502 EPSD|PSP TRPV1 VR1 VLGGVYFFFRGIQYFLQRRPsMKTLFVDSYSEMLFFLQSLF
Q8NER1 S801 EPSD|PSP TRPV1 VR1 SRVSGRHWKNFALVPLLREAsARDRQSAQPEEVYLRQFSGs
Q8NF50 S2077 EPSD|PSP DOCK8 LRPMIERKIPELYKPIFRVEsQKRDsFHRssFRKCETQLsQ
Q8NF50 S2082 EPSD|PSP DOCK8 ERKIPELYKPIFRVEsQKRDsFHRssFRKCETQLsQGs___
Q8NF50 S2087 EPSD|PSP DOCK8 ELYKPIFRVEsQKRDsFHRssFRKCETQLsQGs________
Q8NFA2 S159 SIGNOR NOXO1 P41NOX SH3PXD5 SRVILPTPEEQPLSRAAGRLsIHsLEAQSLRCLQPFCTQDT
Q8NFA2 T346 SIGNOR NOXO1 P41NOX SH3PXD5 APPPTVPtRPsPGAIQSRCCtVTRRALERRPRRQGRPRGCV
Q8TD43 S1145 SIGNOR|EPSD|PSP TRPM4 LTRPC4 ESVHKENFLLARARDKRESDsERLKRTsQKVDLALKQLGHI
Q8TD43 S1152 SIGNOR|EPSD|PSP TRPM4 LTRPC4 FLLARARDKRESDsERLKRTsQKVDLALKQLGHIREYEQRL
Q8TD47 T247 Sugiyama RPS4Y2 RPS4Y2P VIGNGNKPWISLPRGKGIRLtIAEERDKRLAAKQSSG____
Q8TDQ1 T221 PSP CD300LF CD300F CLM1 IGSF13 IREM1 NKIR UNQ3105/PRO10111 GDLCyADLTLQLAGTsPQKAtTKLSSAQVDQVEVEyVTMAS
Q8WTQ7 S36 EPSD|PSP GRK7 GPRK7 YLQARKPsDCDSKELQRRRRsLALPGLQGCAELRQKLSLNF
Q8WX93 S479 Sugiyama PALLD KIAA0992 CGI-151 VLECRVRGAPPLQVQWFRQGsEIQDsPDFRILQKKPRSTAE
Q8WZ42 S11878 EPSD|PSP TTN KVRKLLPERKPEPKEEVVLKsVLRKRPEEEEPKVEPKKLEK
Q8WZ42 S12022 EPSD|PSP TTN GVPKKTPSPIEAERRKLRPGsGGEKPPDEAPFTYQLKAVPL
Q92681 S366 EPSD|PSP RSC1A1 EESCPSITAALKELHELLVVsSKPASENTSEEVICQSETIA
Q92686 S36 SIGNOR|ELM|iPTMNet|EPSD|PSP NRGN ILDIPLDDPGANAAAAKIQAsFRGHMARKKIKSGERGRKGP
Q92793 S437 ELM CREBBP CBP SHWKNCTRHDCPVCLPLKNAsDKRNQQTILGSPASGIQNTI
Q92837 S188 EPSD|PSP FRAT1 CRRGWLRGAAASRRLQQRRGsQPETRTGDDDPHRLLQQLVL
Q92847 T261 PSP GHSR RRRRGDAVVGAsLRDQNHKQtVKMLAVVVFAFILCWLPFHV
Q92879 S178 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 RAMAQTAIKAMHQAQtMEGCssPMVVKFADTQKDKEQKRMA
Q92879 S179 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 AMAQTAIKAMHQAQtMEGCssPMVVKFADTQKDKEQKRMAQ
Q92879 S241 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 NTLGPQYLALYLQLLQQTASsGNLNTLSSLHPMGGLNAMQL
Q92879 S28 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 PDQPDLDAIKMFVGQVPRtWsEKDLRELFEQYGAVYEINVL
Q92879 S300 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 GTNALTTSSSPLSVLTSSGSsPsSSSSNSVNPIASLGALQT
Q92879 S302 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 NALTTSSSPLSVLTSSGSsPsSSSSNSVNPIASLGALQTLA
Q92879 S52 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 LRELFEQYGAVYEINVLRDRsQNPPQSKGCCFVTFYTRKAA
Q92879 T173 PSP CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 VTFTTRAMAQTAIKAMHQAQtMEGCssPMVVKFADTQKDKE
Q92888 S240 SIGNOR|PSP ARHGEF1 NAIGLYMRHLGVRTKSGDKKsGRNFFRKKVMGNRRsDEPAK
Q92890 S299 Sugiyama UFD1 UFD1L KKVEEDEAGGRFVAFsGEGQsLRKKGRKP____________
Q969H0 S10 EPSD|PSP FBXW7 FBW7 FBX30 SEL10 ___________MNQELLSVGsKRRRTGGsLRGNPSssQVDE
Q969H0 S18 SIGNOR|EPSD|PSP FBXW7 FBW7 FBX30 SEL10 ___MNQELLSVGsKRRRTGGsLRGNPSssQVDEEQMNRVVE
Q96A00 T38 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP PPP1R14A CPI17 PPP1INL SRARGPGGsPGGLQKRHARVtVKYDRRELQRRLDVEKWIDG
Q96AX2 T172 SIGNOR|EPSD|PSP RAB37 VIRSEDGETLAREYGVPFLEtSAKTGMNVELAFLAIAKELK
Q96C90 T57 SIGNOR|EPSD|PSP PPP1R14B PLCB3N PNG AGEGPGGADDEGPVRRQGKVtVKYDRKELRKRLNLEEWILE
Q96KS0 S132 SIGNOR|EPSD|PSP EGLN2 EIT6 ARPEAPKRKWAEDGGDAPsPsKRPWARQENQEAEREGGMSC
Q96KS0 S226 EPSD|PSP EGLN2 EIT6 VLAEVEALKRGGRLRDGQLVsQRAIPPRsIRGDQIAWVEGH
Q96KS0 S234 SIGNOR|EPSD|PSP EGLN2 EIT6 KRGGRLRDGQLVsQRAIPPRsIRGDQIAWVEGHEPGCRSIG
Q96MS0 S1330 EPSD|PSP ROBO3 LAAQRVLHPDEEAWLPYSRPsFLSRGQGTSTCSTAGSNSSR
Q96PH1 S536 SIGNOR NOX5 NRLYEsFKASDPLGRGSKRLsRSVtMRKsQRssKGSEILLE
Q96PH1 S544 SIGNOR NOX5 ASDPLGRGSKRLsRSVtMRKsQRssKGSEILLEKHKFCNIK
Q96PH1 T540 SIGNOR NOX5 EsFKASDPLGRGSKRLsRSVtMRKsQRssKGSEILLEKHKF
Q96PX8 S695 SIGNOR SLITRK1 KIAA1910 LRRC12 UNQ233/PRO266 NGPYNADGAHRVYDCGSHSLsD___________________
Q96PY5 S1072 SIGNOR|EPSD FMNL2 FHOD2 KIAA1902 EDIITVLKTVPFTARTAKRGsRFFCEPVLTEEYHY______
Q96QS3 S174 SIGNOR|PSP ARX AAWDTLKISQAPQVSISRSKsYRENGAPFVPPPPALDELGG
Q96RD7 Y199 PSP PANX1 MRS1 UNQ2529/PRO6028 LGQsLWEVSESHFKYPIVEQyLKTKKNSNNLIIKYISCRLL
Q96RI1 S145 SIGNOR NR1H4 BAR FXR HRR1 RIP14 GASAGRIKGDELCVVCGDRAsGYHYNALTCEGCKGFFRRsI
Q96RI1 S164 SIGNOR NR1H4 BAR FXR HRR1 RIP14 AsGYHYNALTCEGCKGFFRRsITKNAVYKCKNGGNCVMDMY
Q96T49 S331 SIGNOR|EPSD|PSP PPP1R16B ANKRD4 KIAA0823 LLELKHKHDVIMKSQLRHKSsLsRRTsSAGSRGKVVRRAsL
Q99418 S392 GPS6|SIGNOR|ELM|EPSD|PSP CYTH2 ARNO PSCD2 PSCD2L QAAVSVDPFYEMLAARKKRIsVKKKQEQP____________
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99623 S39 PSP PHB2 BAP REA MGTALKLLLGAGAVAYGVREsVFTVEGGHRAIFFNRIGGVQ
Q99801 S48 SIGNOR|EPSD|PSP NKX3-1 NKX3.1 NKX3A SFLIQDILRDGAQRQGGRTSsQRQRDPEPEPEPEPEGGRSR
Q99848 S270 Sugiyama EBNA1BP2 EBP2 FGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPGKKGSN
Q9BPZ7 S128 PSP MAPKAP1 MIP1 SIN1 WKERNSKQSAQELKSLFEKKsLKEKPPISGKQSILSVRLEQ
Q9BQE3 S158 EPSD|PSP TUBA1C TUBA6 FHSFGGGTGSGFTSLLMERLsVDYGKKsKLEFSIYPAPQVS
Q9BQE3 S165 GPS6|EPSD|PSP TUBA1C TUBA6 TGSGFTSLLMERLsVDYGKKsKLEFSIYPAPQVSTAVVEPY
Q9BR39 S165 EPSD|PSP JPH2 JP2 QSVPYGMAVVVRsPLRtsLssLRsEHsNGtVAPDSPAsPAS
Q9BR76 S2 SIGNOR|iPTMNet|EPSD|PSP CORO1B ___________________MsFRKVVRQSKFRHVFGQPVKN
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BX40 S349 Sugiyama LSM14B C20orf40 FAM61B RAP55B SSRRTTWAEERKLNtEtFGVsGRFLRGRSSRGGFRGGRGNG
Q9BXS6 S363 Sugiyama NUSAP1 ANKT BM-037 PRO0310 TtEAtQtPVsNKKPVFDLKAsLsRPLNyEPHKGKLKPWGQS
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BZL6 S706 SIGNOR|EPSD|PSP PRKD2 PKD2 HSPC187 DPFPQVKLCDFGFARIIGEKsFRRsVVGtPAyLAPEVLLNQ
Q9BZL6 S710 SIGNOR|EPSD|PSP PRKD2 PKD2 HSPC187 QVKLCDFGFARIIGEKsFRRsVVGtPAyLAPEVLLNQGyNR
Q9BZL6 S876 SIGNOR|EPSD|PSP PRKD2 PKD2 HSPC187 DLGGACPPQDHDMQGLAERIsVL__________________
Q9C0K0 S2 EPSD|PSP BCL11B CTIP2 RIT1 ___________________MsRRKQGNPQHLSQRELITPEA
Q9GZT3 S15 Sugiyama SLIRP C14orf156 DC23 DC50 PD04872 ______MAASAARGAAALRRsINQPVAFVRRIPWTAASSQL
Q9H0B6 S539 Sugiyama KLC2 sEsDLEDVGPTAEWNGDGsGsLRRSGsFGKLRDALRRsSEM
Q9H0H5 T251 Sugiyama RACGAP1 KIAA1478 MGCRACGAP EAVSTIETVPYWtRSRRKtGtLQPWNsDstLNSRQLEPRTE
Q9H1D0 T742 EPSD|PSP TRPV6 ECAC2 PSVSRStSRssANWERLRQGtLRRDLRGIINRGLEDGESWE
Q9H3Q1 S18 SIGNOR|PSP CDC42EP4 BORG4 CEP4 ___MPILKQLVSssVHSKRRsRADLtAEMISAPLGDFRHTM
Q9H3Q1 S80 SIGNOR|PSP CDC42EP4 BORG4 CEP4 PDGEsLDEQPsSsssKRsLLsRKFRGSKRSQSVTRGEREQR
Q9H788 S315 Sugiyama SH2D4A PPP1R38 SH2A LNSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRA
Q9HAN9 S136 EPSD|PSP NMNAT1 NMNAT NsPtLERPGRKRKWTETQDssQKKSLEPKTKAVPKVKLLCG
Q9HBA0 S162 SIGNOR TRPV4 VRL2 VROAC PPPILKVFNRPILFDIVSRGsTADLDGLLPFLLtHKKRLTD
Q9HBA0 S189 SIGNOR TRPV4 VRL2 VROAC LLPFLLtHKKRLTDEEFREPsTGKTCLPKALLNLSNGRNDT
Q9HBA0 T175 SIGNOR TRPV4 VRL2 VROAC FDIVSRGsTADLDGLLPFLLtHKKRLTDEEFREPsTGKTCL
Q9NPC2 T341 SIGNOR|PSP KCNK9 TASK3 KLAPHYFHSISYKIEEISPStLKNSLFPSPISSISPGLHSF
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ66 S887 SIGNOR|ELM|iPTMNet|EPSD PLCB1 KIAA0581 TTTLTPKPPSQALHSQPAPGsVKAPAKTEDLIQSVLTEVEA
Q9NQA5 S299 SIGNOR|EPSD|PSP TRPV5 ECAC1 DLTEIDSWGEELSFLELVVSsDKREARQILEQTPVKELVSF
Q9NQA5 S654 SIGNOR|EPSD|PSP TRPV5 ECAC1 ENHNDQNPLRVLRyVEVFKNsDKEDDQEHPSEKQPSGAESG
Q9NRF2 S161 EPSD|PSP SH2B1 KIAA1299 SH2B STTSSKPKLKKRFSLRSVGRsVRGsVRGILQWRGTVDPPSS
Q9NRF2 S165 EPSD|PSP SH2B1 KIAA1299 SH2B SKPKLKKRFSLRSVGRsVRGsVRGILQWRGTVDPPSSAGPL
Q9NRY4 S1221 GPS6|EPSD|PSP ARHGAP35 GRF1 GRLF1 KIAA1722 P190A p190ARHOGAP DNAVIPYETDEDPRRRNILRsLRRNtKKPKPKPRPsITKAT
Q9NRY4 S1236 GPS6|EPSD|PSP ARHGAP35 GRF1 GRLF1 KIAA1722 P190A p190ARHOGAP RNILRsLRRNtKKPKPKPRPsITKATWESNYFGVPLTTVVT
Q9NRY4 T1226 GPS6|EPSD|PSP ARHGAP35 GRF1 GRLF1 KIAA1722 P190A p190ARHOGAP PYETDEDPRRRNILRsLRRNtKKPKPKPRPsITKATWESNY
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NTW7 S226 PSP ZFP64 ZNF338 KTCDYAAADSSSLNKHLRIHsDERPFKCQICPYASRNSSQL
Q9NXH3 T58 GPS6|ELM|EPSD PPP1R14D GBPI ESKSHPDSSKIPRSRRPSRLtVKYDRGQLQRWLEMEQWVDA
Q9NZ01 S49 Sugiyama TECR GPSN2 SC2 IAEIKNLFTKTHPQWYPARQsLRLDPKGKsLKDEDVLQKLP
Q9P286 S99 PSP PAK5 KIAA1264 PAK7 ETSINGLLEDFDNISVTRSNsLRKESPPTPDQGASSHGPGH
Q9UBS0 S473 GPS6|SIGNOR|ELM|EPSD|PSP RPS6KB2 STK14B PPPPSTTAPLPIRPPSGTKKsKRGRGRPGR___________
Q9UEY8 S693 SIGNOR|ELM|iPTMNet|EPSD ADD3 ADDL sPEGsPsKsPsKKKKKFRTPsFLKKNKKKEKVEA_______
Q9UGV2 S327 Sugiyama NDRG3 KYFLQGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsV
Q9UGV2 S333 Sugiyama NDRG3 MGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsD
Q9UGV2 T329 Sugiyama NDRG3 FLQGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVts
Q9UGV2 T332 Sugiyama NDRG3 GMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQs
Q9UH77 S433 SIGNOR|EPSD|PSP KLHL3 KIAA1129 AYSYKTNEWFFVAPMNTRRSsVGVGVVEGKLYAVGGYDGAS
Q9UI15 S185 Sugiyama TAGLN3 NP25 EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______
Q9UI26 S214 Sugiyama IPO11 RANBP11 QEVSSGNEAAILSSLERTLLsLKVLRKLTVNGFVEPHKNME
Q9UII2 S39 Sugiyama ATP5IF1 ATPI ATPIF1 TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF
Q9UJY1 S14 SIGNOR|ELM|iPTMNet|EPSD HSPB8 CRYAC E2IG1 HSP22 PP1629 _______MADGQMPFSCHYPsRLRRDPFRDsPLsSRLLDDG
Q9UJY1 T63 SIGNOR|ELM|iPTMNet|EPSD HSPB8 CRYAC E2IG1 HSP22 PP1629 DLTASWPDWALPRLsSAWPGtLRSGMVPRGPTATARFGVPA
Q9UKF7 S274 SIGNOR|PSP PITPNC1 PAISISSIPLLPSSVRsAPssAPstPLSTDAPEFLSVPKDR
Q9UKF7 S299 SIGNOR|PSP PITPNC1 PLSTDAPEFLSVPKDRPRKKsAPEtLTLPDPEKKATLNLPG
Q9UKG1 S430 EPSD|PSP APPL1 APPL DIP13A KIAA1428 sLRPAAGQSRPPTARTSSSGsLGSESTNLAALSLDSLVAPD
Q9UKV8 S387 Sugiyama AGO2 EIF2C2 ATARSAPDRQEEISKLMRsAsFNTDPyVREFGIMVKDEMTD
Q9ULW6 T342 Sugiyama NAP1L2 BPX GTAIEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVT
Q9ULW6 T345 Sugiyama NAP1L2 BPX IEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVTEDF
Q9UNF0 S313 PSP PACSIN2 GMAMNWPQFEEWsADLNRtLsRREKKKAtDGVTLTGINQTG
Q9UNX3 S9 Sugiyama RPL26L1 RPL26P1 ____________MKFNPFVtsDRsKNRKRHFNAPSHVRRKI
Q9UNZ2 S74 Sugiyama NSFL1C UBXN2C SQATPssVsRGTAPSDNRVtsFRDLIHDQDEDEEEEEGQRF
Q9UQ13 S297 SIGNOR|EPSD|PSP SHOC2 KIAA0862 PDTIGNLSSLSRLGLRYNRLsAIPRSLAKCSALEELNLENN
Q9UQ13 T71 SIGNOR|EPSD|PSP SHOC2 KIAA0862 KDGKKDSSAAQPGVAFSVDNtIKRPNPAPGTRKKSSNAEVI
Q9UQ35 S2692 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS
Q9UQ35 S854 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sHSsssPHPKVKsGtPPRQGsItsPQANEQsVtPQRRsCFE
Q9UQ80 S360 EPSD|PSP PA2G4 EBP1 PDLyKsEMEVQDAELKALLQssAsRKtQKKKKKKAsKtAEN
Q9UQ80 S363 SIGNOR|iPTMNet|EPSD PA2G4 EBP1 yKsEMEVQDAELKALLQssAsRKtQKKKKKKAsKtAENAts
Q9UQ80 T366 SIGNOR|iPTMNet|EPSD|PSP PA2G4 EBP1 EMEVQDAELKALLQssAsRKtQKKKKKKAsKtAENAtsGEt
Q9UQL6 S259 SIGNOR HDAC5 KIAA0600 KLPLPGPYDSRDDFPLRKTAsEPNLKVRSRLKQKVAERRss
Q9UQL6 S498 SIGNOR HDAC5 KIAA0600 ATSMRTVGKLPRHRPLSRtQssPLPQSPQALQQLVMQQQHQ
Q9Y271 S313 PSP CYSLTR1 CYSLT1 LLYFFSGGNFRKRLSTFRKHsLssVTYVPRKKAsLPEKGEE
Q9Y271 S315 PSP CYSLTR1 CYSLT1 YFFSGGNFRKRLSTFRKHsLssVTYVPRKKAsLPEKGEEIC
Q9Y271 S316 PSP CYSLTR1 CYSLT1 FFSGGNFRKRLSTFRKHsLssVTYVPRKKAsLPEKGEEICK
Q9Y2B0 S55 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDELEWEIAQVDPKKTIQMGsFRINPDGsQsVVEVPyARsE
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2R2 S751 PSP PTPN22 PTPN8 NSTSSKQTLKTPGKSFTRSKsLKILRNMKKSICNSCPPNKP
Q9Y2W1 S257 Sugiyama THRAP3 BCLAF2 TRAP150 sAVsELsPRERsPALKsPLQsVVVRRRsPRPsPVPKPSPPL
Q9Y2X3 S440 Sugiyama NOP58 NOL5 NOP5 HSPC120 EHKSEVKtyDPSGDstLPtCsKKRKIEQVDKEDEITEKKAK
Q9Y3B8 S203 Sugiyama REXO2 SFN SMFN CGI-114 EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK
Q9Y5B9 S650 Sugiyama SUPT16H FACT140 FACTP140 KRYKTREAEEKEKEGIVKQDsLVINLNRsNPKLKDLYIRPN
Q9Y624 S284 SIGNOR|EPSD|PSP F11R JAM1 JCAM UNQ264/PRO301 GHFDRTKKGtSSKKVIysQPsARsEGEFKQTSsFLV_____
Q9Y624 T70 iPTMNet|EPSD F11R JAM1 JCAM UNQ264/PRO301 CAYSGFSSPRVEWKFDQGDTtRLVCYNNKITASYEDRVTFL
Q9Y624 T92 SIGNOR|iPTMNet|EPSD F11R JAM1 JCAM UNQ264/PRO301 LVCYNNKITASYEDRVTFLPtGITFKSVTREDTGTYTCMVS
Q9Y6H6 S82 EPSD|PSP KCNE3 LFVMFLFAVTVGSLILGYTRsRKVDKRSDPYHVYIKNRVSM
Q9Y6K9 S141 GPS6 IKBKG FIP3 NEMO ALREVEHLKRCQQQMAEDKAsVKAQVTSLLGELQESQSRLE
Q9Y6K9 S85 GPS6 IKBKG FIP3 NEMO IRQsNQILRERCEELLHFQAsQREEKEFLMCKFQEARKLVE
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Cell Cycle R-HSA-1640170 3.839151e-13 12.416 1 0
Signal Transduction R-HSA-162582 1.410424e-10 9.851 1 0
Cellular Senescence R-HSA-2559583 2.678154e-10 9.572 0 0
Cell Cycle Checkpoints R-HSA-69620 6.113072e-10 9.214 0 0
Cell Cycle, Mitotic R-HSA-69278 6.924004e-10 9.160 1 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.521629e-09 8.818 0 0
Apoptotic execution phase R-HSA-75153 2.729391e-09 8.564 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.483531e-08 7.829 0 0
Meiotic synapsis R-HSA-1221632 3.661445e-08 7.436 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 6.015597e-08 7.221 0 0
M Phase R-HSA-68886 6.216715e-08 7.206 1 0
DNA methylation R-HSA-5334118 6.642281e-08 7.178 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.126864e-07 6.948 0 0
Axon guidance R-HSA-422475 1.094265e-07 6.961 1 0
PRC2 methylates histones and DNA R-HSA-212300 1.218238e-07 6.914 0 0
Meiosis R-HSA-1500620 1.418915e-07 6.848 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.841226e-07 6.735 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.969235e-07 6.706 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 2.149438e-07 6.668 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.810392e-07 6.551 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 3.793903e-07 6.421 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.167307e-07 6.380 0 0
Nervous system development R-HSA-9675108 4.068044e-07 6.391 1 0
Packaging Of Telomere Ends R-HSA-171306 5.036293e-07 6.298 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 5.036293e-07 6.298 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 5.538641e-07 6.257 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 5.870879e-07 6.231 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 6.726384e-07 6.172 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 7.621664e-07 6.118 0 0
Chromatin organization R-HSA-4839726 9.534072e-07 6.021 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.658665e-06 5.780 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.780646e-06 5.749 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.958238e-06 5.708 0 0
Chromatin modifying enzymes R-HSA-3247509 1.941070e-06 5.712 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.357414e-06 5.628 0 0
Meiotic recombination R-HSA-912446 2.332070e-06 5.632 0 0
HDACs deacetylate histones R-HSA-3214815 2.364088e-06 5.626 0 0
HATs acetylate histones R-HSA-3214847 2.497823e-06 5.602 0 0
Diseases of programmed cell death R-HSA-9645723 2.651666e-06 5.576 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 2.726050e-06 5.564 0 0
Mitotic Prophase R-HSA-68875 3.096036e-06 5.509 1 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.078154e-06 5.512 0 0
NRAGE signals death through JNK R-HSA-193648 3.116656e-06 5.506 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.697914e-06 5.432 0 0
Nucleosome assembly R-HSA-774815 3.961687e-06 5.402 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 3.961687e-06 5.402 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 3.804491e-06 5.420 0 0
G alpha (12/13) signalling events R-HSA-416482 4.152359e-06 5.382 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 4.996530e-06 5.301 0 0
DNA Double Strand Break Response R-HSA-5693606 6.309291e-06 5.200 0 0
Defective pyroptosis R-HSA-9710421 6.957398e-06 5.158 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 7.509678e-06 5.124 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 8.509311e-06 5.070 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 8.514761e-06 5.070 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.041943e-06 5.044 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 8.855631e-06 5.053 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 9.094422e-06 5.041 0 0
Amplification of signal from the kinetochores R-HSA-141424 9.094422e-06 5.041 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 9.422468e-06 5.026 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.086603e-05 4.964 0 0
Apoptosis R-HSA-109581 2.015196e-05 4.696 0 0
Reproduction R-HSA-1474165 2.260484e-05 4.646 0 0
Mitotic Prometaphase R-HSA-68877 2.394292e-05 4.621 0 0
G2/M Checkpoints R-HSA-69481 2.590793e-05 4.587 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.612380e-05 4.583 0 0
Cleavage of the damaged purine R-HSA-110331 2.804215e-05 4.552 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.976781e-05 4.526 0 0
Regulation of TP53 Activity R-HSA-5633007 3.055875e-05 4.515 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.597826e-05 4.444 0 0
Depurination R-HSA-73927 3.769813e-05 4.424 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.984354e-05 4.400 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 4.620272e-05 4.335 0 0
DNA Double-Strand Break Repair R-HSA-5693532 4.669038e-05 4.331 0 0
mRNA Splicing - Major Pathway R-HSA-72163 5.093504e-05 4.293 0 0
Processing of DNA double-strand break ends R-HSA-5693607 4.985355e-05 4.302 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 5.388734e-05 4.269 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 6.151352e-05 4.211 0 0
Mitotic Anaphase R-HSA-68882 6.288255e-05 4.201 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 6.811602e-05 4.167 0 0
Signaling by ALK in cancer R-HSA-9700206 6.811602e-05 4.167 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 7.021199e-05 4.154 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 7.577999e-05 4.120 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 8.407420e-05 4.075 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 8.749827e-05 4.058 0 0
EPH-Ephrin signaling R-HSA-2682334 9.734293e-05 4.012 0 0
mRNA Splicing R-HSA-72172 9.799323e-05 4.009 0 0
ESR-mediated signaling R-HSA-8939211 1.052896e-04 3.978 0 0
Homology Directed Repair R-HSA-5693538 1.113200e-04 3.953 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.384363e-04 3.859 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.450597e-04 3.838 0 0
Depyrimidination R-HSA-73928 1.450597e-04 3.838 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.483950e-04 3.829 1 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.644850e-04 3.784 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.861587e-04 3.730 0 0
Separation of Sister Chromatids R-HSA-2467813 1.873291e-04 3.727 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.926526e-04 3.715 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.038778e-04 3.691 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.211287e-04 3.655 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.434364e-04 3.614 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.465224e-04 3.608 0 0
Interleukin-12 signaling R-HSA-9020591 2.584026e-04 3.588 0 0
Cellular responses to stimuli R-HSA-8953897 2.640918e-04 3.578 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 2.642533e-04 3.578 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 3.146802e-04 3.502 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 3.211064e-04 3.493 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.316054e-04 3.479 0 0
Programmed Cell Death R-HSA-5357801 3.413567e-04 3.467 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.492325e-04 3.457 0 0
Signaling by Hippo R-HSA-2028269 3.939448e-04 3.405 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 4.008176e-04 3.397 0 0
Cellular responses to stress R-HSA-2262752 4.453449e-04 3.351 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.107672e-04 3.292 0 0
mRNA 3'-end processing R-HSA-72187 5.164698e-04 3.287 0 0
Deubiquitination R-HSA-5688426 5.770280e-04 3.239 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 5.840143e-04 3.234 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 6.147631e-04 3.211 0 0
Signaling by VEGF R-HSA-194138 6.509280e-04 3.186 1 0
Chromosome Maintenance R-HSA-73886 6.667633e-04 3.176 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 7.037904e-04 3.153 0 0
RNA Polymerase I Transcription R-HSA-73864 8.083058e-04 3.092 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 8.432907e-04 3.074 0 0
Metalloprotease DUBs R-HSA-5689901 8.432907e-04 3.074 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.004362e-03 2.998 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.004362e-03 2.998 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.022404e-03 2.990 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.107937e-03 2.955 0 0
Recycling pathway of L1 R-HSA-437239 1.167419e-03 2.933 0 0
L1CAM interactions R-HSA-373760 1.303806e-03 2.885 0 0
Cell-Cell communication R-HSA-1500931 1.221424e-03 2.913 0 0
Gene Silencing by RNA R-HSA-211000 1.211504e-03 2.917 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.475491e-03 2.831 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.582754e-03 2.801 0 0
Interleukin-12 family signaling R-HSA-447115 1.710802e-03 2.767 0 0
Ub-specific processing proteases R-HSA-5689880 1.722991e-03 2.764 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.774321e-03 2.751 0 0
Signaling by NOTCH R-HSA-157118 1.779895e-03 2.750 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.811863e-03 2.742 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.859562e-03 2.731 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 1.979175e-03 2.704 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.106865e-03 2.676 0 0
Death Receptor Signaling R-HSA-73887 2.106865e-03 2.676 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.998409e-03 2.699 0 0
Regulation of endogenous retroelements R-HSA-9842860 2.107754e-03 2.676 0 0
Telomere Maintenance R-HSA-157579 2.160973e-03 2.665 0 0
Kinesins R-HSA-983189 2.227529e-03 2.652 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 2.299990e-03 2.638 0 0
Cell junction organization R-HSA-446728 2.302209e-03 2.638 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.619684e-03 2.582 0 0
FOXO-mediated transcription R-HSA-9614085 2.776136e-03 2.557 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 2.887867e-03 2.539 0 0
HCMV Early Events R-HSA-9609690 3.005389e-03 2.522 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.036534e-03 2.518 0 0
Epigenetic regulation of gene expression R-HSA-212165 3.006578e-03 2.522 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 3.005389e-03 2.522 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 2.887867e-03 2.539 0 0
Oncogene Induced Senescence R-HSA-2559585 3.315183e-03 2.479 0 0
MECP2 regulates transcription factors R-HSA-9022707 3.367532e-03 2.473 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.367532e-03 2.473 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 3.515776e-03 2.454 0 0
RMTs methylate histone arginines R-HSA-3214858 3.822935e-03 2.418 0 0
Metabolism of RNA R-HSA-8953854 3.978638e-03 2.400 1 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 4.002439e-03 2.398 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 4.002439e-03 2.398 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 4.002439e-03 2.398 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.543766e-03 2.343 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.543766e-03 2.343 0 0
Gene expression (Transcription) R-HSA-74160 4.515252e-03 2.345 0 0
DNA Repair R-HSA-73894 4.700313e-03 2.328 0 0
Amyloid fiber formation R-HSA-977225 5.254501e-03 2.279 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 5.304456e-03 2.275 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 5.304456e-03 2.275 0 0
DNA Replication Pre-Initiation R-HSA-69002 5.345148e-03 2.272 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 5.583378e-03 2.253 0 0
Activation of HOX genes during differentiation R-HSA-5619507 5.583378e-03 2.253 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 5.590252e-03 2.253 0 0
Signaling by Nuclear Receptors R-HSA-9006931 5.615584e-03 2.251 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 6.112816e-03 2.214 0 0
Activation of RAC1 R-HSA-428540 6.189957e-03 2.208 0 0
Activation of BH3-only proteins R-HSA-114452 6.241228e-03 2.205 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 6.269361e-03 2.203 0 0
Ephrin signaling R-HSA-3928664 6.328824e-03 2.199 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 7.149744e-03 2.146 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 7.134019e-03 2.147 0 0
Nuclear Envelope Breakdown R-HSA-2980766 6.498416e-03 2.187 1 0
Transcriptional Regulation by E2F6 R-HSA-8953750 7.134019e-03 2.147 0 0
RNA Polymerase II Transcription R-HSA-73857 7.208604e-03 2.142 0 0
Selective autophagy R-HSA-9663891 7.352782e-03 2.134 0 0
Semaphorin interactions R-HSA-373755 7.439642e-03 2.128 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 7.617264e-03 2.118 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 7.870339e-03 2.104 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 7.952656e-03 2.099 0 0
Rap1 signalling R-HSA-392517 8.214539e-03 2.085 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 8.594707e-03 2.066 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 8.594707e-03 2.066 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 8.616257e-03 2.065 0 0
Base Excision Repair R-HSA-73884 9.250371e-03 2.034 0 0
Breakdown of the nuclear lamina R-HSA-352238 9.311981e-03 2.031 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 9.828088e-03 2.008 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 1.109303e-02 1.955 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 1.109303e-02 1.955 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.143920e-02 1.942 0 0
Integrin signaling R-HSA-354192 1.120810e-02 1.950 0 0
Post NMDA receptor activation events R-HSA-438064 1.207697e-02 1.918 0 0
Adherens junctions interactions R-HSA-418990 1.120506e-02 1.951 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.281289e-02 1.892 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.360593e-02 1.866 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.474450e-02 1.831 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.485699e-02 1.828 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.552899e-02 1.809 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.588506e-02 1.799 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.591726e-02 1.798 0 0
Nuclear import of Rev protein R-HSA-180746 1.592147e-02 1.798 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.632523e-02 1.787 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.651357e-02 1.782 0 0
Netrin-1 signaling R-HSA-373752 1.863551e-02 1.730 0 0
Aggrephagy R-HSA-9646399 1.881508e-02 1.725 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 1.881508e-02 1.725 0 0
Generic Transcription Pathway R-HSA-212436 1.920212e-02 1.717 0 0
Cell-cell junction organization R-HSA-421270 1.983258e-02 1.703 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.990583e-02 1.701 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 2.014678e-02 1.696 0 0
Notch-HLH transcription pathway R-HSA-350054 2.022388e-02 1.694 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.117815e-02 1.674 0 0
Adrenoceptors R-HSA-390696 2.136894e-02 1.670 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.183593e-02 1.661 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 2.572564e-02 1.590 0 0
Signaling by EGFR R-HSA-177929 2.301997e-02 1.638 0 0
MHC class II antigen presentation R-HSA-2132295 2.414398e-02 1.617 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 2.572564e-02 1.590 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 2.572564e-02 1.590 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.545963e-02 1.594 1 0
Developmental Biology R-HSA-1266738 2.554144e-02 1.593 1 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 2.600033e-02 1.585 0 0
Membrane Trafficking R-HSA-199991 2.688885e-02 1.570 0 0
MITF-M-dependent gene expression R-HSA-9856651 2.756828e-02 1.560 0 0
Signaling by ROBO receptors R-HSA-376176 2.776960e-02 1.556 1 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.818928e-02 1.550 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 2.818928e-02 1.550 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 2.818928e-02 1.550 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 2.950078e-02 1.530 0 0
Gap junction degradation R-HSA-190873 2.950078e-02 1.530 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.955419e-02 1.529 0 0
Neurodegenerative Diseases R-HSA-8863678 2.955419e-02 1.529 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.959219e-02 1.529 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.963499e-02 1.528 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 3.006059e-02 1.522 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 3.006059e-02 1.522 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 3.009245e-02 1.522 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 3.326238e-02 1.478 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 3.326238e-02 1.478 0 0
Diseases of Telomere Maintenance R-HSA-9673013 3.326238e-02 1.478 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 3.326238e-02 1.478 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 3.326238e-02 1.478 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 3.326238e-02 1.478 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 3.326238e-02 1.478 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 3.326238e-02 1.478 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 3.326238e-02 1.478 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 3.509026e-02 1.455 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.208655e-02 1.494 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.519741e-02 1.453 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.519741e-02 1.453 0 0
Translation initiation complex formation R-HSA-72649 3.443930e-02 1.463 0 0
Signal amplification R-HSA-392518 3.489338e-02 1.457 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.375496e-02 1.472 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 3.045155e-02 1.516 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.409916e-02 1.467 0 0
DNA Replication R-HSA-69306 3.398257e-02 1.469 0 0
ISG15 antiviral mechanism R-HSA-1169408 3.109929e-02 1.507 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.532036e-02 1.452 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.540961e-02 1.451 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 3.601274e-02 1.444 0 0
Gap junction trafficking and regulation R-HSA-157858 3.604641e-02 1.443 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.614542e-02 1.442 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 3.635637e-02 1.439 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.667169e-02 1.436 0 0
EPHB-mediated forward signaling R-HSA-3928662 3.759350e-02 1.425 0 0
Receptor Mediated Mitophagy R-HSA-8934903 3.935281e-02 1.405 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 4.024840e-02 1.395 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.052707e-02 1.392 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 4.114850e-02 1.386 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 4.114850e-02 1.386 0 0
Nuclear Receptor transcription pathway R-HSA-383280 4.169758e-02 1.380 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 4.254792e-02 1.371 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 4.316871e-02 1.365 0 0
FLT3 Signaling R-HSA-9607240 4.442395e-02 1.352 0 0
Regulation of TP53 Degradation R-HSA-6804757 4.614769e-02 1.336 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.690948e-02 1.329 0 0
Diseases of mitotic cell cycle R-HSA-9675126 4.760200e-02 1.322 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 4.785412e-02 1.320 1 0
Polo-like kinase mediated events R-HSA-156711 4.801611e-02 1.319 0 0
Regulation of gap junction activity R-HSA-191650 5.477328e-02 1.261 0 0
TNFR1-mediated ceramide production R-HSA-5626978 5.477328e-02 1.261 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 5.477328e-02 1.261 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 5.477328e-02 1.261 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 5.477328e-02 1.261 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 5.477328e-02 1.261 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 5.477328e-02 1.261 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.547649e-02 1.256 0 0
DCC mediated attractive signaling R-HSA-418885 5.583733e-02 1.253 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.583733e-02 1.253 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 5.758030e-02 1.240 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.470233e-02 1.262 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 5.673140e-02 1.246 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 5.406338e-02 1.267 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 5.406338e-02 1.267 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 5.336123e-02 1.273 0 0
G2/M Transition R-HSA-69275 6.128039e-02 1.213 0 0
Cell-extracellular matrix interactions R-HSA-446353 5.583733e-02 1.253 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 5.477328e-02 1.261 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 5.470233e-02 1.262 0 0
NGF-stimulated transcription R-HSA-9031628 6.010967e-02 1.221 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 6.228154e-02 1.206 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 5.436747e-02 1.265 0 0
Protein ubiquitination R-HSA-8852135 5.347553e-02 1.272 0 0
Signaling by NTRKs R-HSA-166520 5.388130e-02 1.269 0 0
Striated Muscle Contraction R-HSA-390522 6.246698e-02 1.204 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 6.246698e-02 1.204 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 6.254683e-02 1.204 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 6.442742e-02 1.191 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 6.442742e-02 1.191 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.501351e-02 1.187 1 0
CD209 (DC-SIGN) signaling R-HSA-5621575 6.708254e-02 1.173 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 6.729041e-02 1.172 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 6.779526e-02 1.169 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.824181e-02 1.166 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 6.824181e-02 1.166 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.824181e-02 1.166 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.824181e-02 1.166 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.824181e-02 1.166 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.824181e-02 1.166 0 0
Oligomerization of connexins into connexons R-HSA-190704 6.829804e-02 1.166 0 0
Transport of glycerol from adipocytes to the liver by Aquaporins R-HSA-432030 6.829804e-02 1.166 0 0
Transport of connexins along the secretory pathway R-HSA-190827 6.829804e-02 1.166 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 6.829804e-02 1.166 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 6.829804e-02 1.166 0 0
HCMV Infection R-HSA-9609646 6.905905e-02 1.161 0 0
Mitophagy R-HSA-5205647 7.090922e-02 1.149 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 7.090922e-02 1.149 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 7.090922e-02 1.149 0 0
Gap junction trafficking R-HSA-190828 7.113569e-02 1.148 0 0
Type I hemidesmosome assembly R-HSA-446107 7.299654e-02 1.137 0 0
Formation of annular gap junctions R-HSA-196025 7.299654e-02 1.137 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 7.299654e-02 1.137 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 7.299654e-02 1.137 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 7.553063e-02 1.122 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.611713e-02 1.119 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 7.659410e-02 1.116 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 7.863523e-02 1.104 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 7.863523e-02 1.104 0 0
G2 Phase R-HSA-68911 7.863523e-02 1.104 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 9.297671e-02 1.032 0 0
ALK mutants bind TKIs R-HSA-9700645 9.297671e-02 1.032 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 7.966144e-02 1.099 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 7.966144e-02 1.099 0 0
Pervasive developmental disorders R-HSA-9005895 7.966144e-02 1.099 0 0
Disorders of Nervous System Development R-HSA-9697154 7.966144e-02 1.099 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 7.966144e-02 1.099 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 7.966144e-02 1.099 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 9.664309e-02 1.015 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 9.664309e-02 1.015 0 0
Disorders of Developmental Biology R-HSA-9675151 8.112495e-02 1.091 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.580791e-02 1.019 0 0
TRP channels R-HSA-3295583 8.894193e-02 1.051 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 9.384474e-02 1.028 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 9.405898e-02 1.027 0 0
G0 and Early G1 R-HSA-1538133 9.551869e-02 1.020 0 0
EGFR downregulation R-HSA-182971 8.456366e-02 1.073 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.257686e-02 1.083 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 9.664309e-02 1.015 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 8.894193e-02 1.051 0 0
GP1b-IX-V activation signalling R-HSA-430116 9.297671e-02 1.032 0 0
Neurexins and neuroligins R-HSA-6794361 9.023960e-02 1.045 0 0
Long-term potentiation R-HSA-9620244 7.755111e-02 1.110 0 0
Muscle contraction R-HSA-397014 9.254701e-02 1.034 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 7.871459e-02 1.104 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.013374e-02 1.045 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 9.664309e-02 1.015 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 9.287479e-02 1.032 0 0
UCH proteinases R-HSA-5689603 9.504576e-02 1.022 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 8.573514e-02 1.067 0 0
Cytokine Signaling in Immune system R-HSA-1280215 8.697798e-02 1.061 0 0
Signaling by Interleukins R-HSA-449147 8.424047e-02 1.074 0 0
HCMV Late Events R-HSA-9610379 9.097548e-02 1.041 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.003788e-02 1.097 0 0
Diseases of DNA repair R-HSA-9675135 8.771106e-02 1.057 0 0
Specification of primordial germ cells R-HSA-9827857 9.580791e-02 1.019 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.003670e-01 0.998 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.003670e-01 0.998 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.012490e-01 0.995 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.025156e-01 0.989 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 1.062132e-01 0.974 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.062132e-01 0.974 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 1.062132e-01 0.974 0 0
GPER1 signaling R-HSA-9634597 1.064879e-01 0.973 0 0
mTORC1-mediated signalling R-HSA-166208 1.068245e-01 0.971 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.072581e-01 0.970 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.102098e-01 0.958 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.105735e-01 0.956 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.109341e-01 0.955 0 0
Regulation of TP53 Expression R-HSA-6804754 1.109341e-01 0.955 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.109341e-01 0.955 0 0
Diseases of cellular response to stress R-HSA-9675132 1.109341e-01 0.955 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.109341e-01 0.955 0 0
Diseases of Cellular Senescence R-HSA-9630747 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.109341e-01 0.955 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.109341e-01 0.955 0 0
Potassium transport channels R-HSA-1296067 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.109341e-01 0.955 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.109341e-01 0.955 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 1.115623e-01 0.952 0 0
Synaptic adhesion-like molecules R-HSA-8849932 1.118074e-01 0.952 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.118074e-01 0.952 0 0
Apoptotic factor-mediated response R-HSA-111471 1.118074e-01 0.952 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.134859e-01 0.945 0 0
Pyroptosis R-HSA-5620971 1.144582e-01 0.941 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 1.152502e-01 0.938 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 1.152502e-01 0.938 0 0
Regulation of CDH11 function R-HSA-9762292 1.152502e-01 0.938 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.152502e-01 0.938 0 0
Signaling by Leptin R-HSA-2586552 1.152502e-01 0.938 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.152965e-01 0.938 0 0
Drug resistance of KIT mutants R-HSA-9669937 1.320255e-01 0.879 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.320255e-01 0.879 0 0
KIT mutants bind TKIs R-HSA-9669921 1.320255e-01 0.879 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.320255e-01 0.879 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 1.320255e-01 0.879 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.320255e-01 0.879 0 0
Imatinib-resistant KIT mutants R-HSA-9669917 1.320255e-01 0.879 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.320255e-01 0.879 0 0
Nilotinib-resistant KIT mutants R-HSA-9669926 1.320255e-01 0.879 0 0
Masitinib-resistant KIT mutants R-HSA-9669924 1.320255e-01 0.879 0 0
Sorafenib-resistant KIT mutants R-HSA-9669936 1.320255e-01 0.879 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.320255e-01 0.879 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 1.320255e-01 0.879 0 0
Regorafenib-resistant KIT mutants R-HSA-9669929 1.320255e-01 0.879 0 0
Sunitinib-resistant KIT mutants R-HSA-9669934 1.320255e-01 0.879 0 0
Dasatinib-resistant KIT mutants R-HSA-9669914 1.320255e-01 0.879 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 1.320255e-01 0.879 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.320255e-01 0.879 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 1.320255e-01 0.879 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.320255e-01 0.879 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.320255e-01 0.879 0 0
CREB phosphorylation R-HSA-199920 1.369638e-01 0.863 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.355200e-01 0.868 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.218288e-01 0.914 0 0
Deadenylation of mRNA R-HSA-429947 1.378487e-01 0.861 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.378487e-01 0.861 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 1.548352e-01 0.810 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 1.434866e-01 0.843 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.434866e-01 0.843 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 1.502195e-01 0.823 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.191836e-01 0.924 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.389319e-01 0.857 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.389319e-01 0.857 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.384184e-01 0.859 0 0
Centrosome maturation R-HSA-380287 1.376152e-01 0.861 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.340252e-01 0.873 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.333790e-01 0.875 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.190140e-01 0.924 0 0
HDMs demethylate histones R-HSA-3214842 1.548352e-01 0.810 0 0
Specification of the neural plate border R-HSA-9834899 1.290699e-01 0.889 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.197704e-01 0.922 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.218288e-01 0.914 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.190140e-01 0.924 0 0
Clathrin-mediated endocytosis R-HSA-8856828 1.172329e-01 0.931 0 0
G1 Phase R-HSA-69236 1.258924e-01 0.900 0 0
Cyclin D associated events in G1 R-HSA-69231 1.258924e-01 0.900 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.228827e-01 0.911 1 0
G-protein mediated events R-HSA-112040 1.191973e-01 0.924 1 0
Opioid Signalling R-HSA-111885 1.473964e-01 0.832 1 0
Transcriptional Regulation by VENTX R-HSA-8853884 1.491445e-01 0.826 0 0
Interleukin-2 signaling R-HSA-9020558 1.396068e-01 0.855 0 0
Signaling by TGFBR3 R-HSA-9839373 1.502195e-01 0.823 0 0
Macroautophagy R-HSA-1632852 1.388127e-01 0.858 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.355200e-01 0.868 0 0
PECAM1 interactions R-HSA-210990 1.396068e-01 0.855 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.355200e-01 0.868 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.359670e-01 0.867 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.491445e-01 0.826 0 0
Interleukin-37 signaling R-HSA-9008059 1.434866e-01 0.843 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.565180e-01 0.805 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.585547e-01 0.800 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 1.585547e-01 0.800 0 0
Axonal growth stimulation R-HSA-209563 1.585547e-01 0.800 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.585547e-01 0.800 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 1.585547e-01 0.800 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 1.585547e-01 0.800 0 0
Downstream signal transduction R-HSA-186763 1.592397e-01 0.798 0 0
Co-inhibition by PD-1 R-HSA-389948 1.599450e-01 0.796 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.607584e-01 0.794 0 0
RET signaling R-HSA-8853659 1.617420e-01 0.791 1 1
Metabolism of non-coding RNA R-HSA-194441 1.619853e-01 0.791 0 0
snRNP Assembly R-HSA-191859 1.619853e-01 0.791 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.657752e-01 0.780 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 1.658057e-01 0.780 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.664411e-01 0.779 0 0
Glycolysis R-HSA-70171 1.677088e-01 0.775 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 1.702674e-01 0.769 0 0
Netrin mediated repulsion signals R-HSA-418886 1.703099e-01 0.769 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.703099e-01 0.769 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 1.703099e-01 0.769 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 1.703099e-01 0.769 0 0
Myogenesis R-HSA-525793 1.727307e-01 0.763 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.733735e-01 0.761 0 0
Co-stimulation by CD28 R-HSA-389356 1.767736e-01 0.753 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.771174e-01 0.752 0 0
Voltage gated Potassium channels R-HSA-1296072 1.771174e-01 0.752 0 0
MTOR signalling R-HSA-165159 1.773389e-01 0.751 0 0
Cilium Assembly R-HSA-5617833 1.802835e-01 0.744 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.804212e-01 0.744 0 0
Defective Mismatch Repair Associated With MLH1 R-HSA-5545483 2.466269e-01 0.608 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 2.466269e-01 0.608 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 2.466269e-01 0.608 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 2.466269e-01 0.608 0 0
Defective Mismatch Repair Associated With PMS2 R-HSA-5632987 2.466269e-01 0.608 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 2.466269e-01 0.608 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 2.091019e-01 0.680 0 0
NADE modulates death signalling R-HSA-205025 2.091019e-01 0.680 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 2.091019e-01 0.680 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.091019e-01 0.680 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.091019e-01 0.680 0 0
PI and PC transport between ER and Golgi membranes R-HSA-1483196 3.461028e-01 0.461 0 0
Signaling by extracellular domain mutants of KIT R-HSA-9680187 3.461028e-01 0.461 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 3.461028e-01 0.461 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 3.461028e-01 0.461 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 3.461028e-01 0.461 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 3.461028e-01 0.461 0 0
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935 3.461028e-01 0.461 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 3.461028e-01 0.461 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 3.461028e-01 0.461 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 3.461028e-01 0.461 0 0
MPS IIID - Sanfilippo syndrome D R-HSA-2206305 3.461028e-01 0.461 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 3.461028e-01 0.461 0 0
Signaling by kinase domain mutants of KIT R-HSA-9669933 3.461028e-01 0.461 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 3.461028e-01 0.461 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 3.461028e-01 0.461 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 3.461028e-01 0.461 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 3.461028e-01 0.461 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.609736e-01 0.583 0 0
IRS activation R-HSA-74713 2.609736e-01 0.583 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.609736e-01 0.583 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 2.609736e-01 0.583 0 0
FGFR1b ligand binding and activation R-HSA-190370 2.056737e-01 0.687 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.935860e-01 0.713 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 2.424997e-01 0.615 1 1
Inactivation of CDC42 and RAC1 R-HSA-428543 2.424997e-01 0.615 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 3.129396e-01 0.505 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 3.129396e-01 0.505 0 0
GLI proteins bind promoters of Hh responsive genes to promote transcription R-HSA-5635851 3.129396e-01 0.505 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 3.129396e-01 0.505 0 0
Phosphorylation of Emi1 R-HSA-176417 3.129396e-01 0.505 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 3.129396e-01 0.505 0 0
HHAT G278V doesn't palmitoylate Hh-Np R-HSA-5658034 4.324489e-01 0.364 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 4.324489e-01 0.364 0 0
Defective visual phototransduction due to STRA6 loss of function R-HSA-9918449 4.324489e-01 0.364 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 4.324489e-01 0.364 0 0
TWIK related potassium channel (TREK) R-HSA-1299503 4.324489e-01 0.364 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 2.226769e-01 0.652 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.226769e-01 0.652 0 0
MAPK3 (ERK1) activation R-HSA-110056 2.802700e-01 0.552 0 0
Folding of actin by CCT/TriC R-HSA-390450 2.802700e-01 0.552 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 2.043019e-01 0.690 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.876900e-01 0.727 0 0
Regulation of KIT signaling R-HSA-1433559 2.528055e-01 0.597 1 1
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 2.528055e-01 0.597 0 0
Retrograde neurotrophin signalling R-HSA-177504 2.528055e-01 0.597 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 3.640713e-01 0.439 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 3.640713e-01 0.439 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.640713e-01 0.439 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 3.640713e-01 0.439 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.185143e-01 0.497 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 3.185143e-01 0.497 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.837041e-01 0.547 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.837041e-01 0.547 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 2.109814e-01 0.676 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.930101e-01 0.714 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 2.109255e-01 0.676 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.820061e-01 0.550 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 3.151152e-01 0.502 0 0
Phase 4 - resting membrane potential R-HSA-5576886 3.151152e-01 0.502 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 3.151152e-01 0.502 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 3.568142e-01 0.448 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 3.568142e-01 0.448 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.568142e-01 0.448 0 0
Signaling by GSK3beta mutants R-HSA-5339716 3.568142e-01 0.448 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 4.136833e-01 0.383 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 4.136833e-01 0.383 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 4.136833e-01 0.383 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 4.136833e-01 0.383 0 0
IFNG signaling activates MAPKs R-HSA-9732724 4.136833e-01 0.383 0 0
SOS-mediated signalling R-HSA-112412 4.136833e-01 0.383 0 0
TFAP2 (AP-2) family regulates transcription of other transcription factors R-HSA-8866906 5.073974e-01 0.295 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 5.073974e-01 0.295 0 0
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023 5.073974e-01 0.295 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 5.073974e-01 0.295 0 0
Defective GCLC causes HAGGSD R-HSA-5578999 5.073974e-01 0.295 0 0
Classical Kir channels R-HSA-1296053 5.073974e-01 0.295 0 0
MET activates PTPN11 R-HSA-8865999 5.073974e-01 0.295 0 0
Invadopodia formation R-HSA-8941237 5.073974e-01 0.295 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 2.097288e-01 0.678 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 2.520105e-01 0.599 1 1
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.091237e-01 0.510 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 3.091237e-01 0.510 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 3.467957e-01 0.460 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 2.733640e-01 0.563 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.022654e-01 0.520 0 0
p75NTR recruits signalling complexes R-HSA-209543 3.948052e-01 0.404 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 3.948052e-01 0.404 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 3.948052e-01 0.404 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 3.948052e-01 0.404 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 3.948052e-01 0.404 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 3.948052e-01 0.404 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 3.948052e-01 0.404 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.402437e-01 0.619 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.402437e-01 0.619 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.402437e-01 0.619 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.365789e-01 0.473 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 3.365789e-01 0.473 0 0
MAP2K and MAPK activation R-HSA-5674135 2.626316e-01 0.581 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.571182e-01 0.590 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 3.785202e-01 0.422 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 3.785202e-01 0.422 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 4.612856e-01 0.336 1 1
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 4.612856e-01 0.336 0 0
RSK activation R-HSA-444257 4.612856e-01 0.336 0 0
Activation of RAS in B cells R-HSA-1169092 4.612856e-01 0.336 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 3.173251e-01 0.498 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.614834e-01 0.583 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.614834e-01 0.583 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.614834e-01 0.583 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.614834e-01 0.583 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.614834e-01 0.583 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 3.514080e-01 0.454 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 4.100826e-01 0.387 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 4.100826e-01 0.387 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.918941e-01 0.407 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 3.762403e-01 0.425 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.574764e-01 0.589 0 0
Activation of the pre-replicative complex R-HSA-68962 4.011062e-01 0.397 0 0
Thromboxane signalling through TP receptor R-HSA-428930 4.194718e-01 0.377 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 4.194718e-01 0.377 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 4.194718e-01 0.377 0 0
cGMP effects R-HSA-418457 4.686678e-01 0.329 0 0
Regulated proteolysis of p75NTR R-HSA-193692 5.065442e-01 0.295 0 0
WNT mediated activation of DVL R-HSA-201688 5.065442e-01 0.295 0 0
Signaling by RAF1 mutants R-HSA-9656223 3.920104e-01 0.407 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 3.473813e-01 0.459 0 0
Trafficking of AMPA receptors R-HSA-399719 4.259069e-01 0.371 1 0
Post-chaperonin tubulin folding pathway R-HSA-389977 4.720020e-01 0.326 0 0
Signaling by NOTCH4 R-HSA-9013694 3.794428e-01 0.421 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.040674e-01 0.298 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 5.040674e-01 0.298 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 5.040674e-01 0.298 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 4.738384e-01 0.324 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 4.749484e-01 0.323 1 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 5.020525e-01 0.299 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 5.020525e-01 0.299 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 5.492478e-01 0.260 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 5.492478e-01 0.260 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 5.492478e-01 0.260 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 4.182231e-01 0.379 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 5.004089e-01 0.301 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 5.004089e-01 0.301 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 5.004089e-01 0.301 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.213903e-01 0.375 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 5.382071e-01 0.269 0 0
Phosphorylation of the APC/C R-HSA-176412 5.382071e-01 0.269 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 4.978236e-01 0.303 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 5.313274e-01 0.275 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.958025e-01 0.305 0 0
Telomere Extension By Telomerase R-HSA-171319 5.264447e-01 0.279 0 0
HIV elongation arrest and recovery R-HSA-167287 5.264447e-01 0.279 0 0
Pausing and recovery of HIV elongation R-HSA-167290 5.264447e-01 0.279 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 5.227043e-01 0.282 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 5.227043e-01 0.282 0 0
G alpha (z) signalling events R-HSA-418597 5.340110e-01 0.272 1 1
Viral mRNA Translation R-HSA-192823 5.475883e-01 0.262 0 0
PKR-mediated signaling R-HSA-9833482 3.676297e-01 0.435 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 5.518654e-01 0.258 0 0
Signaling by NOTCH2 R-HSA-1980145 3.623901e-01 0.441 0 0
Signaling by NOTCH1 R-HSA-1980143 2.179294e-01 0.662 0 0
Chaperonin-mediated protein folding R-HSA-390466 4.920012e-01 0.308 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 1.931267e-01 0.714 0 0
IGF1R signaling cascade R-HSA-2428924 4.413174e-01 0.355 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 4.749484e-01 0.323 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 3.079268e-01 0.512 0 0
Signaling by FGFR3 R-HSA-5654741 4.760971e-01 0.322 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.092031e-01 0.679 0 0
Signaling by FGFR4 R-HSA-5654743 4.342323e-01 0.362 0 0
p75NTR signals via NF-kB R-HSA-193639 2.837041e-01 0.547 0 0
RAF activation R-HSA-5673000 2.294524e-01 0.639 0 0
COPI-mediated anterograde transport R-HSA-6807878 5.500175e-01 0.260 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.553865e-01 0.593 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.935860e-01 0.713 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 1.914699e-01 0.718 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 3.568142e-01 0.448 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 3.467957e-01 0.460 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 2.919600e-01 0.535 0 0
TGFBR3 expression R-HSA-9839394 2.781758e-01 0.556 0 0
p75NTR regulates axonogenesis R-HSA-193697 5.065442e-01 0.295 0 0
Activation of GABAB receptors R-HSA-991365 4.131374e-01 0.384 0 0
Signaling by ERBB2 R-HSA-1227986 2.614834e-01 0.583 1 0
Developmental Cell Lineages R-HSA-9734767 5.259998e-01 0.279 0 0
Signal attenuation R-HSA-74749 2.802700e-01 0.552 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.686678e-01 0.329 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 5.020525e-01 0.299 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.958025e-01 0.305 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.259869e-01 0.371 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 2.130602e-01 0.671 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 4.590097e-01 0.338 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 5.500175e-01 0.260 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 2.424997e-01 0.615 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 4.612856e-01 0.336 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.908321e-01 0.719 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.908321e-01 0.719 0 0
GAB1 signalosome R-HSA-180292 4.100826e-01 0.387 0 0
Gap junction assembly R-HSA-190861 2.294524e-01 0.639 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 2.494461e-01 0.603 1 0
Signaling by PDGF R-HSA-186797 5.311625e-01 0.275 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 2.091019e-01 0.680 0 0
Formation of lateral plate mesoderm R-HSA-9758920 3.129396e-01 0.505 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 2.837041e-01 0.547 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 4.136833e-01 0.383 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 3.267135e-01 0.486 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 3.642177e-01 0.439 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.397618e-01 0.469 0 0
Peptide chain elongation R-HSA-156902 3.042359e-01 0.517 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 3.528639e-01 0.452 0 0
Signalling to RAS R-HSA-167044 5.020525e-01 0.299 0 0
PI3K/AKT activation R-HSA-198203 5.492478e-01 0.260 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 4.598140e-01 0.337 0 0
Transcription of the HIV genome R-HSA-167172 5.114767e-01 0.291 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 5.227043e-01 0.282 0 0
Signaling by RAS mutants R-HSA-6802949 2.402437e-01 0.619 0 0
GABA B receptor activation R-HSA-977444 4.131374e-01 0.384 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 4.933696e-01 0.307 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 5.510321e-01 0.259 0 0
Dopamine receptors R-HSA-390651 2.091019e-01 0.680 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.609736e-01 0.583 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 1.935860e-01 0.713 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.935860e-01 0.713 0 0
NADPH regeneration R-HSA-389542 3.640713e-01 0.439 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.640713e-01 0.439 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 2.109814e-01 0.676 0 0
NF-kB is activated and signals survival R-HSA-209560 3.568142e-01 0.448 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 3.948052e-01 0.404 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 4.100826e-01 0.387 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 2.700992e-01 0.568 0 0
Platelet calcium homeostasis R-HSA-418360 3.762403e-01 0.425 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 5.020525e-01 0.299 0 0
GABA receptor activation R-HSA-977443 4.949279e-01 0.305 0 0
S Phase R-HSA-69242 2.004720e-01 0.698 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 2.485299e-01 0.605 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 4.621613e-01 0.335 0 0
PTEN Regulation R-HSA-6807070 4.511004e-01 0.346 0 0
Circadian clock R-HSA-9909396 3.554318e-01 0.449 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 4.926654e-01 0.307 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 3.948052e-01 0.404 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 2.337763e-01 0.631 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 4.766116e-01 0.322 0 0
Organelle biogenesis and maintenance R-HSA-1852241 3.060538e-01 0.514 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 3.151152e-01 0.502 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.920104e-01 0.407 0 0
Ion homeostasis R-HSA-5578775 4.207320e-01 0.376 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 2.226769e-01 0.652 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.869006e-01 0.728 0 0
Potassium Channels R-HSA-1296071 2.634397e-01 0.579 0 0
Cellular response to chemical stress R-HSA-9711123 2.243088e-01 0.649 0 0
PLC beta mediated events R-HSA-112043 3.880997e-01 0.411 1 0
GPVI-mediated activation cascade R-HSA-114604 4.078971e-01 0.389 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.892626e-01 0.723 0 0
Interferon Signaling R-HSA-913531 5.290458e-01 0.277 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.609736e-01 0.583 0 0
Ca2+ activated K+ channels R-HSA-1296052 4.136833e-01 0.383 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 2.294524e-01 0.639 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 4.612856e-01 0.336 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 4.612856e-01 0.336 0 0
TGFBR3 PTM regulation R-HSA-9839383 4.612856e-01 0.336 0 0
Intraflagellar transport R-HSA-5620924 2.743714e-01 0.562 0 0
FGFR1c ligand binding and activation R-HSA-190373 4.321764e-01 0.364 0 0
Effects of PIP2 hydrolysis R-HSA-114508 3.397618e-01 0.469 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 3.384961e-01 0.470 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.830187e-01 0.548 0 0
Calcineurin activates NFAT R-HSA-2025928 5.065442e-01 0.295 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.809831e-01 0.551 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 4.468249e-01 0.350 1 1
Nuclear RNA decay R-HSA-9930044 4.749484e-01 0.323 0 0
Killing mechanisms R-HSA-9664420 5.382071e-01 0.269 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.382071e-01 0.269 0 0
Transmission across Chemical Synapses R-HSA-112315 4.944959e-01 0.306 1 0
Neuronal System R-HSA-112316 2.199128e-01 0.658 1 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 4.990239e-01 0.302 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.553865e-01 0.593 0 0
Signal transduction by L1 R-HSA-445144 2.820061e-01 0.550 0 0
Cardiac conduction R-HSA-5576891 3.437336e-01 0.464 0 0
Ca-dependent events R-HSA-111996 4.131374e-01 0.384 1 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 2.226769e-01 0.652 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 2.130602e-01 0.671 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 5.065442e-01 0.295 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 4.078971e-01 0.389 0 0
Acyl chain remodelling of PS R-HSA-1482801 4.468249e-01 0.350 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.382071e-01 0.269 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 3.315394e-01 0.479 0 0
DNA Damage Bypass R-HSA-73893 4.173162e-01 0.380 0 0
HIV Life Cycle R-HSA-162587 4.293322e-01 0.367 0 0
Signaling by WNT R-HSA-195721 2.460974e-01 0.609 1 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 3.851283e-01 0.414 0 0
Calmodulin induced events R-HSA-111933 4.078971e-01 0.389 1 1
DAG and IP3 signaling R-HSA-1489509 4.760971e-01 0.322 1 0
Regulated Necrosis R-HSA-5218859 5.114767e-01 0.291 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 3.378712e-01 0.471 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 2.056737e-01 0.687 0 0
Signaling by LTK R-HSA-9842663 1.935860e-01 0.713 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 3.129396e-01 0.505 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.837041e-01 0.547 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 3.151152e-01 0.502 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 3.568142e-01 0.448 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 4.612856e-01 0.336 0 0
p38MAPK events R-HSA-171007 5.040674e-01 0.298 0 0
TET1,2,3 and TDG demethylate DNA R-HSA-5221030 5.492478e-01 0.260 0 0
Eukaryotic Translation Termination R-HSA-72764 4.327717e-01 0.364 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.618488e-01 0.336 0 0
Cardiogenesis R-HSA-9733709 3.173251e-01 0.498 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 3.378712e-01 0.471 0 0
Autophagy R-HSA-9612973 2.735829e-01 0.563 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 5.171787e-01 0.286 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 3.748493e-01 0.426 0 0
DARPP-32 events R-HSA-180024 3.762403e-01 0.425 0 0
CaM pathway R-HSA-111997 4.078971e-01 0.389 1 0
Late Phase of HIV Life Cycle R-HSA-162599 3.376531e-01 0.472 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 3.748493e-01 0.426 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.173251e-01 0.498 0 0
Adaptive Immune System R-HSA-1280218 4.145639e-01 0.382 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.609736e-01 0.583 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.445299e-01 0.612 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 2.843285e-01 0.546 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.762403e-01 0.425 0 0
Rab regulation of trafficking R-HSA-9007101 3.981202e-01 0.400 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.796793e-01 0.553 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.930101e-01 0.714 0 0
mRNA Editing R-HSA-75072 5.065442e-01 0.295 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.603928e-01 0.584 0 0
Signaling by PTK6 R-HSA-8848021 2.130602e-01 0.671 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 2.130602e-01 0.671 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.780090e-01 0.556 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 3.467957e-01 0.460 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 5.040674e-01 0.298 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.802700e-01 0.552 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.365789e-01 0.473 0 0
G-protein beta:gamma signalling R-HSA-397795 4.749484e-01 0.323 0 0
Stimuli-sensing channels R-HSA-2672351 1.930932e-01 0.714 0 0
Signalling to ERKs R-HSA-187687 3.851283e-01 0.414 0 0
MAPK family signaling cascades R-HSA-5683057 2.159087e-01 0.666 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 1.996784e-01 0.700 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 2.466269e-01 0.608 0 0
Inhibition of PKR R-HSA-169131 2.466269e-01 0.608 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.091019e-01 0.680 0 0
MTF1 activates gene expression R-HSA-5660489 2.091019e-01 0.680 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 3.461028e-01 0.461 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 3.461028e-01 0.461 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.609736e-01 0.583 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 2.056737e-01 0.687 0 0
Regulation of IFNG signaling R-HSA-877312 1.935860e-01 0.713 0 0
Unwinding of DNA R-HSA-176974 2.424997e-01 0.615 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 2.424997e-01 0.615 0 0
mRNA Editing: A to I Conversion R-HSA-75064 4.324489e-01 0.364 0 0
C6 deamination of adenosine R-HSA-75102 4.324489e-01 0.364 0 0
Regulation of cortical dendrite branching R-HSA-8985801 4.324489e-01 0.364 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 2.226769e-01 0.652 0 0
Mitochondrial calcium ion transport R-HSA-8949215 1.876900e-01 0.727 0 0
Negative regulation of FLT3 R-HSA-9706369 3.151152e-01 0.502 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 3.151152e-01 0.502 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 4.136833e-01 0.383 0 0
MET interacts with TNS proteins R-HSA-8875513 5.073974e-01 0.295 0 0
Interleukin-7 signaling R-HSA-1266695 2.781758e-01 0.556 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.237896e-01 0.650 0 0
Amine ligand-binding receptors R-HSA-375280 3.191187e-01 0.496 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.093618e-01 0.510 0 0
Degradation of CDH1 R-HSA-9766229 4.173162e-01 0.380 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.040674e-01 0.298 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.670200e-01 0.435 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 4.624204e-01 0.335 0 0
Smooth Muscle Contraction R-HSA-445355 4.958025e-01 0.305 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 5.518654e-01 0.258 0 0
MyD88-independent TLR4 cascade R-HSA-166166 4.624204e-01 0.335 0 0
Host Interactions of HIV factors R-HSA-162909 2.440446e-01 0.613 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 4.901997e-01 0.310 0 0
Hemostasis R-HSA-109582 4.363302e-01 0.360 1 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 5.317157e-01 0.274 0 0
Frs2-mediated activation R-HSA-170968 4.321764e-01 0.364 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 3.177922e-01 0.498 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.264447e-01 0.279 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 5.382071e-01 0.269 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.811324e-01 0.551 0 0
Platelet sensitization by LDL R-HSA-432142 4.100826e-01 0.387 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 4.259869e-01 0.371 0 0
Heme signaling R-HSA-9707616 5.311625e-01 0.275 0 0
Suppression of apoptosis R-HSA-9635465 3.185143e-01 0.497 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 4.612856e-01 0.336 0 0
TBC/RABGAPs R-HSA-8854214 2.999794e-01 0.523 0 0
tRNA processing in the nucleus R-HSA-6784531 2.929021e-01 0.533 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 5.004089e-01 0.301 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.553865e-01 0.593 0 0
Formation of the nephric duct R-HSA-9830364 2.781758e-01 0.556 0 0
Prolonged ERK activation events R-HSA-169893 5.382071e-01 0.269 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 5.313274e-01 0.275 0 0
Cellular response to heat stress R-HSA-3371556 4.498640e-01 0.347 0 0
Uptake and function of anthrax toxins R-HSA-5210891 3.785202e-01 0.422 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 4.612856e-01 0.336 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 5.065442e-01 0.295 0 0
Interleukin-1 processing R-HSA-448706 5.065442e-01 0.295 0 0
Protein hydroxylation R-HSA-9629569 4.720020e-01 0.326 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 3.777973e-01 0.423 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 4.280507e-01 0.369 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 3.777973e-01 0.423 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 3.777973e-01 0.423 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.237896e-01 0.650 0 0
Nephrin family interactions R-HSA-373753 4.720020e-01 0.326 0 0
Pexophagy R-HSA-9664873 5.492478e-01 0.260 0 0
PI Metabolism R-HSA-1483255 3.402801e-01 0.468 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 5.453482e-01 0.263 0 0
SARS-CoV-2-host interactions R-HSA-9705683 2.761809e-01 0.559 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.114767e-01 0.291 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.318329e-01 0.479 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 4.978236e-01 0.303 0 0
Diseases of Immune System R-HSA-5260271 4.978236e-01 0.303 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.011251e-01 0.521 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 4.517127e-01 0.345 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 2.609736e-01 0.583 0 0
DSCAM interactions R-HSA-376172 4.324489e-01 0.364 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.294296e-01 0.639 1 1
Cytochrome c-mediated apoptotic response R-HSA-111461 3.568142e-01 0.448 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 2.951641e-01 0.530 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.173251e-01 0.498 0 0
Syndecan interactions R-HSA-3000170 3.918941e-01 0.407 1 1
ARMS-mediated activation R-HSA-170984 5.065442e-01 0.295 0 0
MAPK1 (ERK2) activation R-HSA-112411 5.065442e-01 0.295 0 0
Tandem pore domain potassium channels R-HSA-1296346 5.492478e-01 0.260 0 0
Activation of SMO R-HSA-5635838 5.382071e-01 0.269 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 5.150265e-01 0.288 0 0
Viral Messenger RNA Synthesis R-HSA-168325 5.131460e-01 0.290 0 0
Signaling by TGFB family members R-HSA-9006936 5.431834e-01 0.265 0 0
Signaling by ALK R-HSA-201556 3.290526e-01 0.483 0 0
Interleukin-1 family signaling R-HSA-446652 5.332862e-01 0.273 0 0
Signaling by NOTCH3 R-HSA-9012852 5.340110e-01 0.272 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 3.091237e-01 0.510 0 0
Other interleukin signaling R-HSA-449836 4.412978e-01 0.355 0 0
SARS-CoV-1-host interactions R-HSA-9692914 2.396399e-01 0.620 0 0
Histamine receptors R-HSA-390650 5.073974e-01 0.295 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.965821e-01 0.706 0 0
Selenocysteine synthesis R-HSA-2408557 5.193974e-01 0.285 0 0
Formation of the anterior neural plate R-HSA-9823739 5.040674e-01 0.298 0 0
NrCAM interactions R-HSA-447038 2.609736e-01 0.583 0 0
Co-inhibition by BTLA R-HSA-9927353 2.609736e-01 0.583 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 3.129396e-01 0.505 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 5.073974e-01 0.295 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.365789e-01 0.473 0 0
Interleukin-18 signaling R-HSA-9012546 4.612856e-01 0.336 0 0
Growth hormone receptor signaling R-HSA-982772 3.918941e-01 0.407 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 4.756494e-01 0.323 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.382071e-01 0.269 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 5.004089e-01 0.301 0 0
Sensory processing of sound R-HSA-9659379 2.570646e-01 0.590 0 0
IRE1alpha activates chaperones R-HSA-381070 4.614726e-01 0.336 0 0
Inositol phosphate metabolism R-HSA-1483249 4.896507e-01 0.310 0 0
Influenza Infection R-HSA-168255 2.494546e-01 0.603 0 0
Signal regulatory protein family interactions R-HSA-391160 2.528055e-01 0.597 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 2.402437e-01 0.619 0 0
Glucose metabolism R-HSA-70326 3.981202e-01 0.400 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 4.100826e-01 0.387 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 3.151152e-01 0.502 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.098149e-01 0.387 0 0
XBP1(S) activates chaperone genes R-HSA-381038 4.765471e-01 0.322 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 4.321764e-01 0.364 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 4.686678e-01 0.329 0 0
Signaling by FGFR1 R-HSA-5654736 5.527206e-01 0.257 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 5.597250e-01 0.252 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 5.597250e-01 0.252 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 5.597250e-01 0.252 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 5.643342e-01 0.248 0 0
rRNA processing R-HSA-72312 5.685809e-01 0.245 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 5.686283e-01 0.245 0 0
RNA Polymerase III Transcription R-HSA-74158 5.686283e-01 0.245 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 5.708736e-01 0.243 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.709584e-01 0.243 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.709584e-01 0.243 0 0
Phase 2 - plateau phase R-HSA-5576893 5.709584e-01 0.243 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.709584e-01 0.243 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 5.709584e-01 0.243 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.709584e-01 0.243 1 1
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 5.709584e-01 0.243 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.709584e-01 0.243 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 5.709584e-01 0.243 0 0
Regulation of CDH1 Function R-HSA-9764561 5.711224e-01 0.243 0 0
HCN channels R-HSA-1296061 5.724523e-01 0.242 0 0
Nucleotide catabolism defects R-HSA-9735786 5.724523e-01 0.242 0 0
ATP sensitive Potassium channels R-HSA-1296025 5.724523e-01 0.242 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 5.724523e-01 0.242 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 5.724523e-01 0.242 0 0
Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate R-HSA-2978092 5.724523e-01 0.242 0 0
Signaling by MAP2K mutants R-HSA-9652169 5.724523e-01 0.242 0 0
Alanine metabolism R-HSA-8964540 5.724523e-01 0.242 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 5.724523e-01 0.242 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 5.724523e-01 0.242 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 5.724523e-01 0.242 0 0
Regulation of RAS by GAPs R-HSA-5658442 5.765343e-01 0.239 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 5.766021e-01 0.239 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 5.766021e-01 0.239 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 5.766021e-01 0.239 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 5.766021e-01 0.239 0 0
Toll-like Receptor Cascades R-HSA-168898 5.788656e-01 0.237 0 0
Protein folding R-HSA-391251 5.820416e-01 0.235 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 5.871620e-01 0.231 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 5.871620e-01 0.231 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 5.871620e-01 0.231 0 0
HIV Infection R-HSA-162906 5.889469e-01 0.230 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 5.891866e-01 0.230 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 5.892822e-01 0.230 0 0
FGFR2b ligand binding and activation R-HSA-190377 5.892822e-01 0.230 0 0
Signaling by APC mutants R-HSA-4839744 5.892822e-01 0.230 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 5.892822e-01 0.230 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 5.892822e-01 0.230 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 5.892822e-01 0.230 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 5.892822e-01 0.230 0 0
Formation of the posterior neural plate R-HSA-9832991 5.892822e-01 0.230 0 0
Chylomicron assembly R-HSA-8963888 5.892822e-01 0.230 0 0
Ionotropic activity of kainate receptors R-HSA-451306 5.892822e-01 0.230 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 5.892822e-01 0.230 0 0
Synthesis of PI R-HSA-1483226 5.892822e-01 0.230 0 0
Prostanoid ligand receptors R-HSA-391908 5.892822e-01 0.230 0 0
ChREBP activates metabolic gene expression R-HSA-163765 5.892822e-01 0.230 0 0
Ovarian tumor domain proteases R-HSA-5689896 5.907645e-01 0.229 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 5.907645e-01 0.229 0 0
HSF1-dependent transactivation R-HSA-3371571 5.955618e-01 0.225 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 5.984771e-01 0.223 0 0
Cargo concentration in the ER R-HSA-5694530 6.005967e-01 0.221 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 6.005967e-01 0.221 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 6.022279e-01 0.220 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 6.022279e-01 0.220 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 6.022279e-01 0.220 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 6.022279e-01 0.220 0 0
Vesicle-mediated transport R-HSA-5653656 6.023622e-01 0.220 0 0
G1/S Transition R-HSA-69206 6.041426e-01 0.219 0 0
Ribosome-associated quality control R-HSA-9948299 6.094968e-01 0.215 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 6.135729e-01 0.212 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 6.135729e-01 0.212 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 6.135729e-01 0.212 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 6.135729e-01 0.212 0 0
Plasma lipoprotein assembly R-HSA-8963898 6.135729e-01 0.212 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 6.238014e-01 0.205 0 0
DNA strand elongation R-HSA-69190 6.238014e-01 0.205 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 6.266074e-01 0.203 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 6.266074e-01 0.203 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 6.266074e-01 0.203 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 6.266074e-01 0.203 0 0
Signaling by AXIN mutants R-HSA-4839735 6.266074e-01 0.203 0 0
Signaling by AMER1 mutants R-HSA-4839748 6.266074e-01 0.203 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 6.266074e-01 0.203 0 0
Activation of AMPA receptors R-HSA-399710 6.289191e-01 0.201 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 6.289191e-01 0.201 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 6.289191e-01 0.201 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 6.289191e-01 0.201 0 0
PTK6 Down-Regulation R-HSA-8849472 6.289191e-01 0.201 0 0
Activation of AKT2 R-HSA-165158 6.289191e-01 0.201 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 6.289191e-01 0.201 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 6.289191e-01 0.201 0 0
Trafficking of myristoylated proteins to the cilium R-HSA-5624138 6.289191e-01 0.201 0 0
Muscarinic acetylcholine receptors R-HSA-390648 6.289191e-01 0.201 0 0
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403 6.289191e-01 0.201 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 6.289191e-01 0.201 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 6.289191e-01 0.201 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 6.289191e-01 0.201 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 6.289191e-01 0.201 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.319535e-01 0.199 0 0
PKA activation in glucagon signalling R-HSA-164378 6.319535e-01 0.199 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 6.319535e-01 0.199 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 6.319535e-01 0.199 0 0
Mismatch Repair R-HSA-5358508 6.319535e-01 0.199 0 0
PKA activation R-HSA-163615 6.319535e-01 0.199 0 0
FGFR1 ligand binding and activation R-HSA-190242 6.319535e-01 0.199 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.319535e-01 0.199 0 0
Chaperone Mediated Autophagy R-HSA-9613829 6.319535e-01 0.199 0 0
Tie2 Signaling R-HSA-210993 6.319535e-01 0.199 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.323118e-01 0.199 0 0
Parasite infection R-HSA-9664407 6.323118e-01 0.199 0 0
Leishmania phagocytosis R-HSA-9664417 6.323118e-01 0.199 0 0
Stabilization of p53 R-HSA-69541 6.331704e-01 0.198 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 6.365152e-01 0.196 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 6.389084e-01 0.195 0 0
Tight junction interactions R-HSA-420029 6.389084e-01 0.195 0 0
MAP kinase activation R-HSA-450294 6.410978e-01 0.193 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 6.418478e-01 0.193 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 6.434820e-01 0.191 0 0
FGFR1 mutant receptor activation R-HSA-1839124 6.461782e-01 0.190 0 0
Interferon alpha/beta signaling R-HSA-909733 6.487946e-01 0.188 0 0
Interleukin-2 family signaling R-HSA-451927 6.533743e-01 0.185 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 6.533743e-01 0.185 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 6.533743e-01 0.185 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 6.575701e-01 0.182 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.600995e-01 0.180 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.600995e-01 0.180 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 6.600995e-01 0.180 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.600995e-01 0.180 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.600995e-01 0.180 1 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.600995e-01 0.180 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 6.612407e-01 0.180 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 6.612407e-01 0.180 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 6.612407e-01 0.180 0 0
Interleukin-15 signaling R-HSA-8983432 6.612407e-01 0.180 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 6.612407e-01 0.180 0 0
OAS antiviral response R-HSA-8983711 6.612407e-01 0.180 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 6.631336e-01 0.178 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 6.631336e-01 0.178 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 6.631336e-01 0.178 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 6.631336e-01 0.178 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 6.653143e-01 0.177 0 0
Miscellaneous transport and binding events R-HSA-5223345 6.676983e-01 0.175 0 0
Mitochondrial biogenesis R-HSA-1592230 6.727017e-01 0.172 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 6.735978e-01 0.172 0 0
Plus-strand DNA synthesis R-HSA-164525 6.779311e-01 0.169 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 6.779311e-01 0.169 0 0
PDE3B signalling R-HSA-165160 6.779311e-01 0.169 0 0
PKB-mediated events R-HSA-109703 6.779311e-01 0.169 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 6.779311e-01 0.169 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 6.779311e-01 0.169 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 6.779311e-01 0.169 0 0
Signaling by MAPK mutants R-HSA-9652817 6.779311e-01 0.169 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 6.779311e-01 0.169 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 6.779311e-01 0.169 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 6.779311e-01 0.169 0 0
Ceramide signalling R-HSA-193681 6.779311e-01 0.169 0 0
Synthesis of PS R-HSA-1483101 6.779311e-01 0.169 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 6.779311e-01 0.169 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 6.779311e-01 0.169 0 0
Formation of the Editosome R-HSA-75094 6.779311e-01 0.169 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 6.779311e-01 0.169 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 6.779311e-01 0.169 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 6.779311e-01 0.169 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 6.798395e-01 0.168 0 0
Regulation of mitotic cell cycle R-HSA-453276 6.798395e-01 0.168 0 0
TNF signaling R-HSA-75893 6.837497e-01 0.165 0 0
Adipogenesis R-HSA-9843745 6.851920e-01 0.164 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 6.862270e-01 0.164 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 6.862270e-01 0.164 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 6.862270e-01 0.164 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.866531e-01 0.163 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 6.866531e-01 0.163 0 0
Formation of definitive endoderm R-HSA-9823730 6.866531e-01 0.163 0 0
Negative regulation of MET activity R-HSA-6807004 6.866531e-01 0.163 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 6.883413e-01 0.162 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 6.883413e-01 0.162 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 6.883413e-01 0.162 0 0
Signaling by Hedgehog R-HSA-5358351 6.910605e-01 0.160 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 6.916660e-01 0.160 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 6.916660e-01 0.160 0 0
Neutrophil degranulation R-HSA-6798695 6.919588e-01 0.160 0 0
Adenylate cyclase activating pathway R-HSA-170660 6.932421e-01 0.159 0 0
FGFR2c ligand binding and activation R-HSA-190375 6.932421e-01 0.159 0 0
Interleukin-6 signaling R-HSA-1059683 6.932421e-01 0.159 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 6.932421e-01 0.159 0 0
Chylomicron remodeling R-HSA-8963901 6.932421e-01 0.159 0 0
FGFR4 ligand binding and activation R-HSA-190322 6.932421e-01 0.159 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 6.932421e-01 0.159 0 0
Maturation of nucleoprotein R-HSA-9683610 6.932421e-01 0.159 0 0
FGFR3 mutant receptor activation R-HSA-2033514 6.932421e-01 0.159 0 0
CD28 dependent Vav1 pathway R-HSA-389359 6.932421e-01 0.159 0 0
SARS-CoV-2 Infection R-HSA-9694516 6.942820e-01 0.158 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 6.956064e-01 0.158 0 0
Ion channel transport R-HSA-983712 7.005012e-01 0.155 0 0
Hedgehog 'off' state R-HSA-5610787 7.025976e-01 0.153 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 7.080945e-01 0.150 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 7.080945e-01 0.150 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 7.081789e-01 0.150 0 0
Switching of origins to a post-replicative state R-HSA-69052 7.087339e-01 0.150 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 7.116208e-01 0.148 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 7.116208e-01 0.148 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 7.116208e-01 0.148 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 7.116208e-01 0.148 0 0
Basigin interactions R-HSA-210991 7.116208e-01 0.148 0 0
PI3K Cascade R-HSA-109704 7.123045e-01 0.147 0 0
ER to Golgi Anterograde Transport R-HSA-199977 7.166746e-01 0.145 0 0
Signaling by LTK in cancer R-HSA-9842640 7.204720e-01 0.142 0 0
Erythropoietin activates STAT5 R-HSA-9027283 7.204720e-01 0.142 0 0
STAT5 Activation R-HSA-9645135 7.204720e-01 0.142 0 0
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors R-HSA-629587 7.204720e-01 0.142 0 0
Uncoating of the HIV Virion R-HSA-162585 7.204720e-01 0.142 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 7.204720e-01 0.142 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 7.204720e-01 0.142 0 0
Defective CHST3 causes SEDCJD R-HSA-3595172 7.204720e-01 0.142 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 7.204720e-01 0.142 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 7.204720e-01 0.142 0 0
Intracellular metabolism of fatty acids regulates insulin secretion R-HSA-434313 7.204720e-01 0.142 0 0
Abacavir transmembrane transport R-HSA-2161517 7.204720e-01 0.142 0 0
VLDL assembly R-HSA-8866423 7.204720e-01 0.142 0 0
Lipid particle organization R-HSA-8964572 7.204720e-01 0.142 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 7.204720e-01 0.142 0 0
Nef and signal transduction R-HSA-164944 7.204720e-01 0.142 0 0
Removal of the Flap Intermediate R-HSA-69166 7.227025e-01 0.141 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 7.227025e-01 0.141 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 7.227025e-01 0.141 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 7.227025e-01 0.141 0 0
FGFR3c ligand binding and activation R-HSA-190372 7.227025e-01 0.141 0 0
Prolactin receptor signaling R-HSA-1170546 7.227025e-01 0.141 0 0
HDL assembly R-HSA-8963896 7.227025e-01 0.141 0 0
Zinc transporters R-HSA-435354 7.227025e-01 0.141 0 0
Non-canonical inflammasome activation R-HSA-9686114 7.227025e-01 0.141 0 0
RUNX2 regulates bone development R-HSA-8941326 7.269523e-01 0.138 0 0
Signaling by SCF-KIT R-HSA-1433557 7.270456e-01 0.138 1 1
Signaling by Erythropoietin R-HSA-9006335 7.289898e-01 0.137 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 7.289898e-01 0.137 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 7.289898e-01 0.137 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 7.289898e-01 0.137 0 0
Extension of Telomeres R-HSA-180786 7.304666e-01 0.136 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 7.339050e-01 0.134 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 7.350248e-01 0.134 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 7.350248e-01 0.134 0 0
Signaling by PDGFR in disease R-HSA-9671555 7.350248e-01 0.134 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 7.359160e-01 0.133 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 7.359160e-01 0.133 1 0
G alpha (s) signalling events R-HSA-418555 7.395144e-01 0.131 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 7.438192e-01 0.129 0 0
Orc1 removal from chromatin R-HSA-68949 7.438192e-01 0.129 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 7.438192e-01 0.129 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 7.449153e-01 0.128 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 7.454726e-01 0.128 0 0
DAP12 signaling R-HSA-2424491 7.486690e-01 0.126 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.486690e-01 0.126 0 0
Erythropoietin activates RAS R-HSA-9027284 7.497347e-01 0.125 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 7.497347e-01 0.125 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.497347e-01 0.125 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 7.497347e-01 0.125 0 0
Processive synthesis on the lagging strand R-HSA-69183 7.497347e-01 0.125 0 0
Telomere C-strand synthesis initiation R-HSA-174430 7.497347e-01 0.125 0 0
FGFR3 ligand binding and activation R-HSA-190239 7.497347e-01 0.125 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 7.497347e-01 0.125 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 7.497347e-01 0.125 0 0
Protein methylation R-HSA-8876725 7.497347e-01 0.125 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 7.512962e-01 0.124 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 7.569005e-01 0.121 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 7.569005e-01 0.121 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 7.569005e-01 0.121 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 7.569005e-01 0.121 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 7.573961e-01 0.121 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 7.573961e-01 0.121 0 0
CHL1 interactions R-HSA-447041 7.573961e-01 0.121 0 0
Recycling of eIF2:GDP R-HSA-72731 7.573961e-01 0.121 0 0
Defective CHSY1 causes TPBS R-HSA-3595177 7.573961e-01 0.121 0 0
FGFR3b ligand binding and activation R-HSA-190371 7.573961e-01 0.121 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 7.573961e-01 0.121 0 0
mRNA Editing: C to U Conversion R-HSA-72200 7.573961e-01 0.121 0 0
Disinhibition of SNARE formation R-HSA-114516 7.573961e-01 0.121 1 1
LDL remodeling R-HSA-8964041 7.573961e-01 0.121 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 7.573961e-01 0.121 0 0
VLDL clearance R-HSA-8964046 7.573961e-01 0.121 0 0
Regulation of PTEN localization R-HSA-8948747 7.573961e-01 0.121 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 7.573961e-01 0.121 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 7.573961e-01 0.121 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 7.586314e-01 0.120 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 7.588784e-01 0.120 0 0
Formation of paraxial mesoderm R-HSA-9793380 7.588784e-01 0.120 0 0
Somitogenesis R-HSA-9824272 7.594725e-01 0.119 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 7.672337e-01 0.115 0 0
Regulation of insulin secretion R-HSA-422356 7.675950e-01 0.115 1 0
Interleukin-17 signaling R-HSA-448424 7.725383e-01 0.112 0 0
Unfolded Protein Response (UPR) R-HSA-381119 7.742769e-01 0.111 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 7.744661e-01 0.111 0 0
Atorvastatin ADME R-HSA-9754706 7.744661e-01 0.111 0 0
Regulation of BACH1 activity R-HSA-9708530 7.744661e-01 0.111 0 0
Regulation of TNFR1 signaling R-HSA-5357905 7.745847e-01 0.111 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 7.781861e-01 0.109 0 0
Platelet homeostasis R-HSA-418346 7.801567e-01 0.108 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.803695e-01 0.108 1 1
Inwardly rectifying K+ channels R-HSA-1296065 7.847074e-01 0.105 0 0
Hedgehog 'on' state R-HSA-5632684 7.847302e-01 0.105 0 0
Platelet degranulation R-HSA-114608 7.868186e-01 0.104 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 7.869474e-01 0.104 0 0
Reverse Transcription of HIV RNA R-HSA-162589 7.894445e-01 0.103 0 0
Minus-strand DNA synthesis R-HSA-164516 7.894445e-01 0.103 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 7.894445e-01 0.103 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 7.894445e-01 0.103 0 0
phospho-PLA2 pathway R-HSA-111995 7.894445e-01 0.103 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 7.894445e-01 0.103 0 0
Highly calcium permeable nicotinic acetylcholine receptors R-HSA-629597 7.894445e-01 0.103 0 0
Interleukin-9 signaling R-HSA-8985947 7.894445e-01 0.103 0 0
Regulation by c-FLIP R-HSA-3371378 7.894445e-01 0.103 0 0
Co-stimulation by ICOS R-HSA-9927354 7.894445e-01 0.103 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 7.894445e-01 0.103 0 0
Dimerization of procaspase-8 R-HSA-69416 7.894445e-01 0.103 0 0
Alpha-defensins R-HSA-1462054 7.894445e-01 0.103 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 7.894445e-01 0.103 0 0
Sodium/Proton exchangers R-HSA-425986 7.894445e-01 0.103 0 0
Interleukin-23 signaling R-HSA-9020933 7.894445e-01 0.103 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 7.935204e-01 0.100 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 7.935204e-01 0.100 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 7.935204e-01 0.100 0 0
HIV Transcription Elongation R-HSA-167169 7.935204e-01 0.100 0 0
Attenuation phase R-HSA-3371568 7.935204e-01 0.100 0 0
Generation of second messenger molecules R-HSA-202433 7.935204e-01 0.100 0 0
Signaling by FGFR2 R-HSA-5654738 7.962082e-01 0.099 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 7.962570e-01 0.099 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 7.962570e-01 0.099 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 7.962570e-01 0.099 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 7.970328e-01 0.099 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 7.970328e-01 0.099 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 7.970328e-01 0.099 0 0
Passive transport by Aquaporins R-HSA-432047 7.970328e-01 0.099 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 7.970328e-01 0.099 0 0
Synthesis of PG R-HSA-1483148 7.970328e-01 0.099 0 0
Response to metal ions R-HSA-5660526 7.970328e-01 0.099 0 0
Insulin receptor signalling cascade R-HSA-74751 7.973876e-01 0.098 0 0
Interleukin-1 signaling R-HSA-9020702 7.982370e-01 0.098 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 7.993225e-01 0.097 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 8.071290e-01 0.093 0 0
Ca2+ pathway R-HSA-4086398 8.076689e-01 0.093 1 1
Regulation of HSF1-mediated heat shock response R-HSA-3371453 8.077766e-01 0.093 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 8.080113e-01 0.093 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 8.080113e-01 0.093 0 0
Cellular response to hypoxia R-HSA-1234174 8.091458e-01 0.092 0 0
IRS-mediated signalling R-HSA-112399 8.116619e-01 0.091 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 8.138508e-01 0.089 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 8.138508e-01 0.089 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 8.138508e-01 0.089 0 0
Integration of energy metabolism R-HSA-163685 8.140671e-01 0.089 1 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 8.165019e-01 0.088 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 8.172609e-01 0.088 0 0
Interleukin-21 signaling R-HSA-9020958 8.172609e-01 0.088 0 0
CASP8 activity is inhibited R-HSA-5218900 8.172609e-01 0.088 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 8.172609e-01 0.088 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 8.172609e-01 0.088 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 8.172609e-01 0.088 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 8.172609e-01 0.088 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 8.172609e-01 0.088 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 8.172609e-01 0.088 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 8.172609e-01 0.088 0 0
Lipophagy R-HSA-9613354 8.172609e-01 0.088 0 0
Cellular response to mitochondrial stress R-HSA-9840373 8.172609e-01 0.088 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 8.172609e-01 0.088 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 8.175750e-01 0.087 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.175750e-01 0.087 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 8.175750e-01 0.087 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 8.175750e-01 0.087 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 8.175750e-01 0.087 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 8.175750e-01 0.087 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 8.175750e-01 0.087 0 0
Signaling by ERBB4 R-HSA-1236394 8.184266e-01 0.087 0 0
HIV Transcription Initiation R-HSA-167161 8.216808e-01 0.085 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.216808e-01 0.085 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.216808e-01 0.085 0 0
Intra-Golgi traffic R-HSA-6811438 8.216808e-01 0.085 0 0
Signaling by FGFR1 in disease R-HSA-5655302 8.216808e-01 0.085 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.216808e-01 0.085 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.216808e-01 0.085 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 8.234065e-01 0.084 0 0
Parasitic Infection Pathways R-HSA-9824443 8.274575e-01 0.082 0 0
Leishmania infection R-HSA-9658195 8.274575e-01 0.082 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 8.301386e-01 0.081 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 8.301386e-01 0.081 0 0
Dual Incision in GG-NER R-HSA-5696400 8.308925e-01 0.080 0 0
NOD1/2 Signaling Pathway R-HSA-168638 8.308925e-01 0.080 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 8.345535e-01 0.079 0 0
Activated point mutants of FGFR2 R-HSA-2033519 8.362336e-01 0.078 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 8.362336e-01 0.078 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 8.362336e-01 0.078 0 0
Binding and entry of HIV virion R-HSA-173107 8.414038e-01 0.075 0 0
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors R-HSA-629594 8.414038e-01 0.075 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 8.414038e-01 0.075 1 1
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 8.414038e-01 0.075 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 8.414038e-01 0.075 0 0
Interleukin-27 signaling R-HSA-9020956 8.414038e-01 0.075 0 0
Formation of intermediate mesoderm R-HSA-9761174 8.414038e-01 0.075 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 8.414038e-01 0.075 0 0
Maturation of spike protein R-HSA-9683686 8.414038e-01 0.075 0 0
Formation of apoptosome R-HSA-111458 8.414038e-01 0.075 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 8.414038e-01 0.075 0 0
Josephin domain DUBs R-HSA-5689877 8.414038e-01 0.075 0 0
Regulation of the apoptosome activity R-HSA-9627069 8.414038e-01 0.075 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 8.414038e-01 0.075 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 8.424666e-01 0.074 0 0
PERK regulates gene expression R-HSA-381042 8.443302e-01 0.073 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 8.451867e-01 0.073 0 0
Cristae formation R-HSA-8949613 8.451867e-01 0.073 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 8.457399e-01 0.073 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.466559e-01 0.072 0 0
Response of Mtb to phagocytosis R-HSA-9637690 8.466559e-01 0.072 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 8.505411e-01 0.070 0 0
Regulation of signaling by CBL R-HSA-912631 8.531478e-01 0.069 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 8.531478e-01 0.069 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 8.531478e-01 0.069 0 0
Translesion Synthesis by POLH R-HSA-110320 8.531478e-01 0.069 0 0
Maturation of nucleoprotein R-HSA-9694631 8.531478e-01 0.069 0 0
G1/S-Specific Transcription R-HSA-69205 8.568561e-01 0.067 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.568561e-01 0.067 0 0
FLT3 signaling in disease R-HSA-9682385 8.568561e-01 0.067 0 0
HSF1 activation R-HSA-3371511 8.568561e-01 0.067 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 8.580161e-01 0.067 0 0
DAP12 interactions R-HSA-2172127 8.580161e-01 0.067 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 8.590631e-01 0.066 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.590631e-01 0.066 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 8.590631e-01 0.066 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 8.623583e-01 0.064 0 0
Dissolution of Fibrin Clot R-HSA-75205 8.623583e-01 0.064 0 0
FGFRL1 modulation of FGFR1 signaling R-HSA-5658623 8.623583e-01 0.064 0 0
vRNA Synthesis R-HSA-192814 8.623583e-01 0.064 0 0
Bicarbonate transporters R-HSA-425381 8.623583e-01 0.064 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 8.623583e-01 0.064 0 0
Transport of RCbl within the body R-HSA-9758890 8.623583e-01 0.064 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 8.623583e-01 0.064 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 8.623583e-01 0.064 0 0
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290 8.623583e-01 0.064 0 0
LGI-ADAM interactions R-HSA-5682910 8.623583e-01 0.064 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 8.623583e-01 0.064 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 8.623583e-01 0.064 0 0
Cellular response to starvation R-HSA-9711097 8.644277e-01 0.063 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 8.654231e-01 0.063 0 0
Immune System R-HSA-168256 8.654729e-01 0.063 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 8.684526e-01 0.061 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 8.684526e-01 0.061 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 8.684526e-01 0.061 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 8.684526e-01 0.061 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 8.686635e-01 0.061 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 8.686635e-01 0.061 0 0
Interferon gamma signaling R-HSA-877300 8.703156e-01 0.060 0 0
Late endosomal microautophagy R-HSA-9615710 8.718361e-01 0.060 0 0
SARS-CoV Infections R-HSA-9679506 8.727885e-01 0.059 0 0
Signaling by MET R-HSA-6806834 8.735347e-01 0.059 0 0
Viral Infection Pathways R-HSA-9824446 8.743010e-01 0.058 0 0
MET promotes cell motility R-HSA-8875878 8.793428e-01 0.056 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 8.798520e-01 0.056 0 0
DS-GAG biosynthesis R-HSA-2022923 8.805453e-01 0.055 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 8.805453e-01 0.055 0 0
Presynaptic nicotinic acetylcholine receptors R-HSA-622323 8.805453e-01 0.055 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 8.805453e-01 0.055 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 8.805453e-01 0.055 0 0
ERKs are inactivated R-HSA-202670 8.805453e-01 0.055 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 8.805453e-01 0.055 0 0
Sodium/Calcium exchangers R-HSA-425561 8.805453e-01 0.055 0 0
Integration of provirus R-HSA-162592 8.805453e-01 0.055 0 0
G-protein activation R-HSA-202040 8.822780e-01 0.054 0 0
FGFR2 ligand binding and activation R-HSA-190241 8.822780e-01 0.054 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 8.822780e-01 0.054 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 8.822780e-01 0.054 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 8.822780e-01 0.054 0 0
Early Phase of HIV Life Cycle R-HSA-162594 8.822780e-01 0.054 0 0
Lagging Strand Synthesis R-HSA-69186 8.822780e-01 0.054 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 8.822780e-01 0.054 0 0
Acyl chain remodelling of PG R-HSA-1482925 8.822780e-01 0.054 0 0
ERK/MAPK targets R-HSA-198753 8.822780e-01 0.054 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 8.822780e-01 0.054 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 8.835735e-01 0.054 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.835735e-01 0.054 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 8.879412e-01 0.052 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.879412e-01 0.052 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 8.884805e-01 0.051 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.943422e-01 0.048 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 8.943422e-01 0.048 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 8.947477e-01 0.048 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 8.947477e-01 0.048 0 0
Attachment and Entry R-HSA-9694614 8.947477e-01 0.048 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 8.947477e-01 0.048 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 8.963300e-01 0.048 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 8.963300e-01 0.048 0 0
IRAK1 recruits IKK complex R-HSA-937039 8.963300e-01 0.048 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 8.963300e-01 0.048 0 0
Repression of WNT target genes R-HSA-4641265 8.963300e-01 0.048 0 0
GRB2 events in EGFR signaling R-HSA-179812 8.963300e-01 0.048 0 0
Interleukin-35 Signalling R-HSA-8984722 8.963300e-01 0.048 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 8.963300e-01 0.048 0 0
VLDLR internalisation and degradation R-HSA-8866427 8.963300e-01 0.048 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.963300e-01 0.048 0 0
MET activates RAS signaling R-HSA-8851805 8.963300e-01 0.048 0 0
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286 8.963300e-01 0.048 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 8.963300e-01 0.048 0 0
Polymerase switching R-HSA-69091 8.963300e-01 0.048 0 0
Leading Strand Synthesis R-HSA-69109 8.963300e-01 0.048 0 0
Estrogen biosynthesis R-HSA-193144 8.963300e-01 0.048 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 8.963300e-01 0.048 0 0
Plasma lipoprotein remodeling R-HSA-8963899 8.966329e-01 0.047 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 8.986968e-01 0.046 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 8.986968e-01 0.046 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 8.986968e-01 0.046 0 0
Glycogen metabolism R-HSA-8982491 8.986968e-01 0.046 0 0
Nucleotide Excision Repair R-HSA-5696398 8.995114e-01 0.046 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.018877e-01 0.045 0 0
Signaling by FGFR R-HSA-190236 9.018877e-01 0.045 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.019702e-01 0.045 0 0
Gastrulation R-HSA-9758941 9.025267e-01 0.045 0 0
Signaling by WNT in cancer R-HSA-4791275 9.042070e-01 0.044 0 0
Signaling by KIT in disease R-HSA-9669938 9.059784e-01 0.043 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.059784e-01 0.043 0 0
FGFR2 alternative splicing R-HSA-6803529 9.059784e-01 0.043 0 0
Free fatty acid receptors R-HSA-444209 9.059784e-01 0.043 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 9.059784e-01 0.043 0 0
LDL clearance R-HSA-8964038 9.059784e-01 0.043 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.059784e-01 0.043 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 9.059784e-01 0.043 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.066157e-01 0.043 0 0
Potential therapeutics for SARS R-HSA-9679191 9.072530e-01 0.042 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.085316e-01 0.042 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 9.100298e-01 0.041 0 0
Acetylcholine binding and downstream events R-HSA-181431 9.100298e-01 0.041 0 0
Postsynaptic nicotinic acetylcholine receptors R-HSA-622327 9.100298e-01 0.041 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 9.100298e-01 0.041 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 9.100298e-01 0.041 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 9.100298e-01 0.041 0 0
Diseases of nucleotide metabolism R-HSA-9735804 9.100298e-01 0.041 0 0
Mtb iron assimilation by chelation R-HSA-1222449 9.100298e-01 0.041 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 9.100298e-01 0.041 0 0
Formation of axial mesoderm R-HSA-9796292 9.100298e-01 0.041 0 0
Processing of SMDT1 R-HSA-8949664 9.100298e-01 0.041 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 9.100298e-01 0.041 0 0
Synthesis of DNA R-HSA-69239 9.106312e-01 0.041 0 0
Regulation of necroptotic cell death R-HSA-5675482 9.132311e-01 0.039 0 0
GPCR downstream signalling R-HSA-388396 9.151142e-01 0.039 1 0
Interleukin-20 family signaling R-HSA-8854691 9.160799e-01 0.038 0 0
Biosynthesis of maresins R-HSA-9018682 9.160799e-01 0.038 0 0
RAB geranylgeranylation R-HSA-8873719 9.179099e-01 0.037 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.192880e-01 0.037 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 9.214748e-01 0.036 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.214748e-01 0.036 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 9.219198e-01 0.035 0 0
CRMPs in Sema3A signaling R-HSA-399956 9.219198e-01 0.035 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 9.219198e-01 0.035 0 0
Hydrolysis of LPC R-HSA-1483115 9.219198e-01 0.035 0 0
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661 9.219198e-01 0.035 0 0
N-glycan trimming and elongation in the cis-Golgi R-HSA-964739 9.219198e-01 0.035 0 0
Physiological factors R-HSA-5578768 9.219198e-01 0.035 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 9.219198e-01 0.035 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 9.219198e-01 0.035 0 0
Acyl chain remodeling of CL R-HSA-1482798 9.219198e-01 0.035 0 0
P2Y receptors R-HSA-417957 9.219198e-01 0.035 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.225977e-01 0.035 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.225977e-01 0.035 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.225977e-01 0.035 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 9.236643e-01 0.034 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.241133e-01 0.034 0 0
Interleukin-6 family signaling R-HSA-6783589 9.251543e-01 0.034 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.251543e-01 0.034 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.257999e-01 0.033 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.257999e-01 0.033 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.257999e-01 0.033 0 0
PPARA activates gene expression R-HSA-1989781 9.281517e-01 0.032 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.289958e-01 0.032 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.289958e-01 0.032 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.293596e-01 0.032 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.299011e-01 0.032 0 0
Mitochondrial protein import R-HSA-1268020 9.299011e-01 0.032 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.299011e-01 0.032 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.300300e-01 0.032 0 0
Selenoamino acid metabolism R-HSA-2408522 9.308526e-01 0.031 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.318406e-01 0.031 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.318406e-01 0.031 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 9.322391e-01 0.030 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 9.322391e-01 0.030 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 9.322391e-01 0.030 0 0
G beta:gamma signalling through BTK R-HSA-8964315 9.322391e-01 0.030 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 9.322391e-01 0.030 0 0
Translesion synthesis by REV1 R-HSA-110312 9.322391e-01 0.030 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 9.322391e-01 0.030 0 0
Synthesis of 12-eicosatetraenoic acid derivatives R-HSA-2142712 9.322391e-01 0.030 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 9.322391e-01 0.030 0 0
DNA Damage Reversal R-HSA-73942 9.322391e-01 0.030 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 9.332966e-01 0.030 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 9.332966e-01 0.030 0 0
G protein gated Potassium channels R-HSA-1296059 9.332966e-01 0.030 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 9.332966e-01 0.030 0 0
Laminin interactions R-HSA-3000157 9.332966e-01 0.030 0 0
Regulation of Apoptosis R-HSA-169911 9.358492e-01 0.029 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.358492e-01 0.029 0 0
Ion transport by P-type ATPases R-HSA-936837 9.403180e-01 0.027 0 0
MET activates PTK2 signaling R-HSA-8874081 9.405947e-01 0.027 0 0
Signaling by EGFR in Cancer R-HSA-1643713 9.405947e-01 0.027 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.405947e-01 0.027 0 0
Translesion synthesis by POLI R-HSA-5656121 9.411951e-01 0.026 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 9.411951e-01 0.026 0 0
Activation of the phototransduction cascade R-HSA-2485179 9.411951e-01 0.026 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 9.411951e-01 0.026 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 9.411951e-01 0.026 1 1
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 9.411951e-01 0.026 0 0
Differentiation of T cells R-HSA-9945266 9.411951e-01 0.026 0 0
Fructose catabolism R-HSA-70350 9.411951e-01 0.026 0 0
Attachment and Entry R-HSA-9678110 9.411951e-01 0.026 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.413049e-01 0.026 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.413049e-01 0.026 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.420868e-01 0.026 0 0
Glycosphingolipid transport R-HSA-9845576 9.420868e-01 0.026 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.431286e-01 0.025 0 0
G alpha (q) signalling events R-HSA-416476 9.436814e-01 0.025 1 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.465593e-01 0.024 1 1
Signaling by FGFR3 in disease R-HSA-5655332 9.471295e-01 0.024 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 9.471295e-01 0.024 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 9.471295e-01 0.024 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.471295e-01 0.024 0 0
Degradation of DVL R-HSA-4641258 9.477576e-01 0.023 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.489679e-01 0.023 0 0
Translesion synthesis by POLK R-HSA-5655862 9.489679e-01 0.023 0 0
Scavenging by Class B Receptors R-HSA-3000471 9.489679e-01 0.023 0 0
Vitamin B6 activation to pyridoxal phosphate R-HSA-964975 9.489679e-01 0.023 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 9.489679e-01 0.023 0 0
Galactose catabolism R-HSA-70370 9.489679e-01 0.023 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 9.489679e-01 0.023 0 0
Signaling by Insulin receptor R-HSA-74752 9.506972e-01 0.022 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.506972e-01 0.022 0 0
ABC-family proteins mediated transport R-HSA-382556 9.508259e-01 0.022 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.512609e-01 0.022 0 0
Synthesis of PA R-HSA-1483166 9.518346e-01 0.021 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.529078e-01 0.021 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.529078e-01 0.021 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 9.529078e-01 0.021 0 0
Prednisone ADME R-HSA-9757110 9.529751e-01 0.021 0 0
Kidney development R-HSA-9830369 9.533616e-01 0.021 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.545268e-01 0.020 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 9.557136e-01 0.020 0 0
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265 9.557136e-01 0.020 0 0
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770 9.557136e-01 0.020 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 9.557136e-01 0.020 0 0
Sulfide oxidation to sulfate R-HSA-1614517 9.557136e-01 0.020 0 0
Metal ion SLC transporters R-HSA-425410 9.557968e-01 0.020 0 0
TCR signaling R-HSA-202403 9.573937e-01 0.019 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.575802e-01 0.019 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.581996e-01 0.019 0 0
Termination of translesion DNA synthesis R-HSA-5656169 9.581996e-01 0.019 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.581996e-01 0.019 0 0
Integrin cell surface interactions R-HSA-216083 9.588685e-01 0.018 0 0
Regulation of beta-cell development R-HSA-186712 9.596834e-01 0.018 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 9.615680e-01 0.017 1 1
G beta:gamma signalling through PLC beta R-HSA-418217 9.615680e-01 0.017 0 0
Presynaptic function of Kainate receptors R-HSA-500657 9.615680e-01 0.017 0 0
Biosynthesis of Lipoxins (LX) R-HSA-2142700 9.615680e-01 0.017 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.615680e-01 0.017 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 9.615680e-01 0.017 0 0
Neurotransmitter clearance R-HSA-112311 9.628650e-01 0.016 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.628650e-01 0.016 0 0
Glutathione conjugation R-HSA-156590 9.631515e-01 0.016 0 0
Azathioprine ADME R-HSA-9748787 9.635402e-01 0.016 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.656498e-01 0.015 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.656498e-01 0.015 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.656498e-01 0.015 0 0
Maturation of spike protein R-HSA-9694548 9.656498e-01 0.015 0 0
Aquaporin-mediated transport R-HSA-445717 9.663432e-01 0.015 0 0
ER-Phagosome pathway R-HSA-1236974 9.665364e-01 0.015 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 9.666487e-01 0.015 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.666487e-01 0.015 0 0
Methionine salvage pathway R-HSA-1237112 9.666487e-01 0.015 0 0
HDL remodeling R-HSA-8964058 9.666487e-01 0.015 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 9.666487e-01 0.015 0 0
The NLRP3 inflammasome R-HSA-844456 9.666487e-01 0.015 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.668470e-01 0.015 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.669205e-01 0.015 0 0
The phototransduction cascade R-HSA-2514856 9.669205e-01 0.015 1 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.670277e-01 0.015 0 0
Budding and maturation of HIV virion R-HSA-162588 9.670277e-01 0.015 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.670277e-01 0.015 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.672861e-01 0.014 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.691191e-01 0.014 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.691191e-01 0.014 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.691191e-01 0.014 0 0
Translation of Structural Proteins R-HSA-9683701 9.691191e-01 0.014 0 0
HS-GAG degradation R-HSA-2024096 9.707391e-01 0.013 0 0
Phospholipid metabolism R-HSA-1483257 9.710353e-01 0.013 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 9.710581e-01 0.013 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 9.710581e-01 0.013 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.710581e-01 0.013 0 0
Creatine metabolism R-HSA-71288 9.710581e-01 0.013 0 0
Keratan sulfate degradation R-HSA-2022857 9.710581e-01 0.013 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.710581e-01 0.013 0 0
Signaling by NODAL R-HSA-1181150 9.710581e-01 0.013 0 0
Glycogen synthesis R-HSA-3322077 9.710581e-01 0.013 0 0
Formation of the cornified envelope R-HSA-6809371 9.736777e-01 0.012 0 0
Defective B3GALTL causes PpS R-HSA-5083635 9.740458e-01 0.011 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 9.744497e-01 0.011 0 0
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896 9.748847e-01 0.011 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.748847e-01 0.011 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 9.748847e-01 0.011 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 9.750875e-01 0.011 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.753884e-01 0.011 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.754554e-01 0.011 0 0
Heme degradation R-HSA-189483 9.769899e-01 0.010 0 0
Surfactant metabolism R-HSA-5683826 9.776437e-01 0.010 0 0
CS-GAG biosynthesis R-HSA-2022870 9.782055e-01 0.010 0 0
Glutathione synthesis and recycling R-HSA-174403 9.782055e-01 0.010 0 0
Ribavirin ADME R-HSA-9755088 9.782055e-01 0.010 0 0
Assembly Of The HIV Virion R-HSA-175474 9.782055e-01 0.010 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.796094e-01 0.009 0 0
eNOS activation R-HSA-203615 9.796094e-01 0.009 0 0
Hyaluronan metabolism R-HSA-2142845 9.796094e-01 0.009 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 9.796094e-01 0.009 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 9.798525e-01 0.009 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.799487e-01 0.009 0 0
Fanconi Anemia Pathway R-HSA-6783310 9.799487e-01 0.009 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.799487e-01 0.009 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.810874e-01 0.008 0 0
Biosynthesis of D-series resolvins R-HSA-9018676 9.810874e-01 0.008 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 9.810874e-01 0.008 0 0
Fructose metabolism R-HSA-5652084 9.810874e-01 0.008 0 0
Ethanol oxidation R-HSA-71384 9.810874e-01 0.008 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.819387e-01 0.008 0 0
Cholesterol biosynthesis R-HSA-191273 9.820164e-01 0.008 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.820258e-01 0.008 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 9.820258e-01 0.008 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.820258e-01 0.008 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 9.825579e-01 0.008 1 0
Regulation of PTEN mRNA translation R-HSA-8943723 9.835884e-01 0.007 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 9.835884e-01 0.007 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 9.835884e-01 0.007 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 9.835884e-01 0.007 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.835884e-01 0.007 0 0
Formation of the ureteric bud R-HSA-9830674 9.835884e-01 0.007 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 9.835884e-01 0.007 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.835884e-01 0.007 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.840086e-01 0.007 0 0
Triglyceride catabolism R-HSA-163560 9.840086e-01 0.007 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.840086e-01 0.007 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.851400e-01 0.007 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 9.855052e-01 0.006 0 0
COPII-mediated vesicle transport R-HSA-204005 9.855052e-01 0.006 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.857588e-01 0.006 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.857588e-01 0.006 0 0
Synthesis of dolichyl-phosphate R-HSA-446199 9.857588e-01 0.006 0 0
Complex III assembly R-HSA-9865881 9.857588e-01 0.006 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.858471e-01 0.006 0 0
O-glycosylation of TSR domain-containing proteins R-HSA-5173214 9.858471e-01 0.006 0 0
NCAM1 interactions R-HSA-419037 9.858471e-01 0.006 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.858973e-01 0.006 0 0
tRNA Aminoacylation R-HSA-379724 9.865881e-01 0.006 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.868369e-01 0.006 0 0
Purine salvage R-HSA-74217 9.874792e-01 0.005 0 0
Elastic fibre formation R-HSA-1566948 9.874792e-01 0.005 0 0
Hyaluronan degradation R-HSA-2160916 9.876423e-01 0.005 0 0
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives R-HSA-9027604 9.876423e-01 0.005 0 0
Retinoid cycle disease events R-HSA-2453864 9.876423e-01 0.005 0 0
Diseases associated with visual transduction R-HSA-2474795 9.876423e-01 0.005 0 0
Diseases of the neuronal system R-HSA-9675143 9.876423e-01 0.005 0 0
Signaling by GPCR R-HSA-372790 9.879172e-01 0.005 1 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.885962e-01 0.005 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.889272e-01 0.005 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.889272e-01 0.005 0 0
Urea cycle R-HSA-70635 9.892767e-01 0.005 0 0
Abacavir ADME R-HSA-2161522 9.892767e-01 0.005 0 0
Neddylation R-HSA-8951664 9.894229e-01 0.005 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.896747e-01 0.005 0 0
Signaling by FGFR in disease R-HSA-1226099 9.901715e-01 0.004 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.902114e-01 0.004 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.902443e-01 0.004 0 0
tRNA processing R-HSA-72306 9.904058e-01 0.004 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.906951e-01 0.004 0 0
Biosynthesis of DPAn-3 SPMs R-HSA-9025094 9.906951e-01 0.004 0 0
Triglyceride biosynthesis R-HSA-75109 9.906951e-01 0.004 0 0
Insulin processing R-HSA-264876 9.906951e-01 0.004 0 0
Synthesis of PE R-HSA-1483213 9.906951e-01 0.004 0 0
Signaling by BMP R-HSA-201451 9.906951e-01 0.004 0 0
Collagen formation R-HSA-1474290 9.910829e-01 0.004 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 9.910921e-01 0.004 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.917633e-01 0.004 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 9.919259e-01 0.004 0 0
Formation of the Early Elongation Complex R-HSA-113418 9.919259e-01 0.004 0 0
Insulin receptor recycling R-HSA-77387 9.919259e-01 0.004 0 0
Pyrimidine salvage R-HSA-73614 9.919259e-01 0.004 0 0
Inflammasomes R-HSA-622312 9.919259e-01 0.004 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.921486e-01 0.003 0 0
RSV-host interactions R-HSA-9833110 9.924199e-01 0.003 0 0
Translation of Structural Proteins R-HSA-9694635 9.926930e-01 0.003 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.928248e-01 0.003 0 0
Pyruvate metabolism R-HSA-70268 9.928564e-01 0.003 0 0
mRNA Capping R-HSA-72086 9.929940e-01 0.003 0 0
Thyroxine biosynthesis R-HSA-209968 9.929940e-01 0.003 0 0
Biosynthesis of EPA-derived SPMs R-HSA-9018679 9.929940e-01 0.003 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 9.929940e-01 0.003 0 0
SLC transporter disorders R-HSA-5619102 9.933245e-01 0.003 0 0
Interleukin-10 signaling R-HSA-6783783 9.933866e-01 0.003 0 0
ABC transporter disorders R-HSA-5619084 9.933866e-01 0.003 0 0
Paracetamol ADME R-HSA-9753281 9.934275e-01 0.003 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.939209e-01 0.003 0 0
Mucopolysaccharidoses R-HSA-2206281 9.939209e-01 0.003 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.941965e-01 0.003 0 0
Neurotransmitter release cycle R-HSA-112310 9.946336e-01 0.002 0 0
Biosynthesis of DPA-derived SPMs R-HSA-9018683 9.947251e-01 0.002 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.947251e-01 0.002 0 0
Peptide hormone metabolism R-HSA-2980736 9.950390e-01 0.002 0 0
Dual incision in TC-NER R-HSA-6782135 9.953362e-01 0.002 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.953603e-01 0.002 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.953603e-01 0.002 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.954230e-01 0.002 0 0
Retinoid metabolism and transport R-HSA-975634 9.957917e-01 0.002 0 0
Metabolism of cofactors R-HSA-8978934 9.957917e-01 0.002 0 0
Triglyceride metabolism R-HSA-8979227 9.958433e-01 0.002 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.959074e-01 0.002 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.959074e-01 0.002 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.960287e-01 0.002 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.962223e-01 0.002 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.962966e-01 0.002 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.962966e-01 0.002 0 0
Synthesis of PC R-HSA-1483191 9.963911e-01 0.002 0 0
CS/DS degradation R-HSA-2024101 9.965542e-01 0.001 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.965542e-01 0.001 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.965542e-01 0.001 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.965542e-01 0.001 0 0
Nucleotide salvage R-HSA-8956321 9.967017e-01 0.001 0 0
Collagen degradation R-HSA-1442490 9.967017e-01 0.001 0 0
Gluconeogenesis R-HSA-70263 9.968184e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.969593e-01 0.001 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.970102e-01 0.001 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.970102e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.972516e-01 0.001 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.972735e-01 0.001 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.974058e-01 0.001 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.975292e-01 0.001 0 0
HS-GAG biosynthesis R-HSA-2022928 9.977492e-01 0.001 0 0
Protein localization R-HSA-9609507 9.978525e-01 0.001 0 0
PCP/CE pathway R-HSA-4086400 9.980386e-01 0.001 1 0
Degradation of AXIN R-HSA-4641257 9.980471e-01 0.001 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.980471e-01 0.001 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.980471e-01 0.001 0 0
Collagen chain trimerization R-HSA-8948216 9.980471e-01 0.001 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.980700e-01 0.001 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.980700e-01 0.001 0 0
Post-translational protein modification R-HSA-597592 9.981546e-01 0.001 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.982438e-01 0.001 0 0
Downstream TCR signaling R-HSA-202424 9.982578e-01 0.001 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.983056e-01 0.001 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.983121e-01 0.001 0 0
Pentose phosphate pathway R-HSA-71336 9.985299e-01 0.001 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.985299e-01 0.001 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.985299e-01 0.001 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.985934e-01 0.001 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.987308e-01 0.001 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.988933e-01 0.000 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.988933e-01 0.000 0 0
ECM proteoglycans R-HSA-3000178 9.989825e-01 0.000 0 0
Dectin-2 family R-HSA-5621480 9.989877e-01 0.000 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.991528e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.991528e-01 0.000 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.992170e-01 0.000 0 0
Peroxisomal protein import R-HSA-9033241 9.992170e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.992324e-01 0.000 0 0
Defensins R-HSA-1461973 9.992773e-01 0.000 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.992827e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.993346e-01 0.000 1 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.993730e-01 0.000 0 0
Proteasome assembly R-HSA-9907900 9.993730e-01 0.000 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.993730e-01 0.000 0 0
The canonical retinoid cycle in rods (twilight vision) R-HSA-2453902 9.994560e-01 0.000 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.994560e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.994772e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.995666e-01 0.000 0 0
Xenobiotics R-HSA-211981 9.995893e-01 0.000 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.995906e-01 0.000 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.995906e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.995940e-01 0.000 0 0
Keratan sulfate/keratin metabolism R-HSA-1638074 9.996918e-01 0.000 0 0
Translation R-HSA-72766 9.997000e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.997183e-01 0.000 1 0
Nicotinate metabolism R-HSA-196807 9.997218e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.997218e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.997438e-01 0.000 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.997442e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.997442e-01 0.000 0 0
Complex IV assembly R-HSA-9864848 9.997681e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.997797e-01 0.000 1 0
Glycosphingolipid catabolism R-HSA-9840310 9.998117e-01 0.000 0 0
Nucleotide biosynthesis R-HSA-8956320 9.998255e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.998348e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.998550e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.998653e-01 0.000 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.998686e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.998860e-01 0.000 0 0
Disease R-HSA-1643685 9.999243e-01 0.000 0 0
Sialic acid metabolism R-HSA-4085001 9.999256e-01 0.000 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.999256e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999345e-01 0.000 0 0
Metabolism of polyamines R-HSA-351202 9.999355e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.999440e-01 0.000 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.999555e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.999579e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.999635e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.999668e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999668e-01 0.000 0 0
Latent infection - Other responses of Mtb to phagocytosis R-HSA-1222499 9.999683e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999701e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.999724e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999726e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999742e-01 0.000 0 0
Metabolism of steroid hormones R-HSA-196071 9.999762e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.999772e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.999799e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.999844e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999846e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999846e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999862e-01 0.000 0 0
Aspirin ADME R-HSA-9749641 9.999898e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.999898e-01 0.000 0 0
Iron uptake and transport R-HSA-917937 9.999924e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.999931e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999943e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999949e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999950e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.999957e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999973e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999977e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999985e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999988e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999988e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999990e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.999995e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999995e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999996e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.999996e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999997e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999999e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999999e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 1.000000e+00 0.000 0 0
Metabolism of nucleotides R-HSA-15869 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
O-linked glycosylation R-HSA-5173105 1.000000e+00 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 1.000000e+00 0.000 0 0
Regulation of Complement cascade R-HSA-977606 1.000000e+00 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Respiratory electron transport R-HSA-611105 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Complement cascade R-HSA-166658 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 1 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 1 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 1 0
Cell Cycle, Mitotic R-HSA-69278 1.110223e-16 15.955 1 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 1 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 1 0
M Phase R-HSA-68886 2.553513e-15 14.593 1 0
Signal Transduction R-HSA-162582 5.750955e-14 13.240 1 0
Cellular responses to stimuli R-HSA-8953897 5.373479e-14 13.270 0 0
Mitotic Prophase R-HSA-68875 2.654543e-13 12.576 1 0
Cellular responses to stress R-HSA-2262752 4.949374e-13 12.305 0 0
Cell Cycle Checkpoints R-HSA-69620 6.966649e-13 12.157 0 0
Signaling by ROBO receptors R-HSA-376176 6.319389e-12 11.199 1 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.404288e-11 10.853 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.404288e-11 10.853 0 0
Attenuation phase R-HSA-3371568 2.227440e-11 10.652 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 9.176704e-11 10.037 0 0
HSF1-dependent transactivation R-HSA-3371571 1.223162e-10 9.913 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.174664e-10 9.930 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.609227e-10 9.793 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.609227e-10 9.793 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 2.548862e-10 9.594 0 0
Peptide chain elongation R-HSA-156902 2.485836e-10 9.605 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.608869e-10 9.584 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.299782e-10 9.482 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 4.103580e-10 9.387 0 0
Cellular response to heat stress R-HSA-3371556 4.939307e-10 9.306 0 0
Metabolism of RNA R-HSA-8953854 5.975330e-10 9.224 1 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 7.136218e-10 9.147 0 0
Formation of a pool of free 40S subunits R-HSA-72689 7.256108e-10 9.139 0 0
G2/M DNA damage checkpoint R-HSA-69473 7.340335e-10 9.134 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 9.508844e-10 9.022 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.220298e-09 8.914 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 1.930245e-09 8.714 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.936301e-09 8.713 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.869434e-09 8.728 0 0
DNA methylation R-HSA-5334118 2.532830e-09 8.596 0 0
HSF1 activation R-HSA-3371511 3.018948e-09 8.520 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 3.838410e-09 8.416 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 4.462961e-09 8.350 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 4.906865e-09 8.309 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 5.947593e-09 8.226 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 6.699144e-09 8.174 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 8.169642e-09 8.088 0 0
Eukaryotic Translation Termination R-HSA-72764 8.145695e-09 8.089 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.763201e-09 8.010 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.081672e-08 7.966 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.495317e-08 7.825 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.662159e-08 7.779 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 2.071775e-08 7.684 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 2.195766e-08 7.658 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.234227e-08 7.651 0 0
Nucleosome assembly R-HSA-774815 2.658541e-08 7.575 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.658541e-08 7.575 0 0
Packaging Of Telomere Ends R-HSA-171306 3.100612e-08 7.509 0 0
Selenocysteine synthesis R-HSA-2408557 3.073274e-08 7.512 0 0
Influenza Infection R-HSA-168255 3.550372e-08 7.450 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.974159e-08 7.401 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.974159e-08 7.401 0 0
Cellular Senescence R-HSA-2559583 4.131466e-08 7.384 0 0
Meiotic recombination R-HSA-912446 4.385588e-08 7.358 0 0
Viral mRNA Translation R-HSA-192823 4.676509e-08 7.330 0 0
Mitotic Prometaphase R-HSA-68877 4.705420e-08 7.327 0 0
G2/M Checkpoints R-HSA-69481 5.161474e-08 7.287 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 6.527554e-08 7.185 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 6.527554e-08 7.185 0 0
Meiotic synapsis R-HSA-1221632 8.008718e-08 7.096 0 0
mRNA Splicing R-HSA-72172 1.068426e-07 6.971 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.159924e-07 6.936 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.275478e-07 6.894 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.390094e-07 6.857 0 0
Meiosis R-HSA-1500620 1.493290e-07 6.826 0 0
Depurination R-HSA-73927 1.442585e-07 6.841 0 0
Apoptotic execution phase R-HSA-75153 1.529681e-07 6.815 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.569690e-07 6.804 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.599825e-07 6.796 0 0
Ribosome-associated quality control R-HSA-9948299 1.811275e-07 6.742 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 2.440917e-07 6.612 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 2.992086e-07 6.524 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 3.138805e-07 6.503 0 0
Developmental Biology R-HSA-1266738 3.270920e-07 6.485 1 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 3.291621e-07 6.483 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 3.584674e-07 6.446 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 4.339488e-07 6.363 0 0
Cleavage of the damaged purine R-HSA-110331 4.475171e-07 6.349 0 0
HDACs deacetylate histones R-HSA-3214815 5.275551e-07 6.278 0 0
DNA Replication Pre-Initiation R-HSA-69002 5.279763e-07 6.277 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 5.437213e-07 6.265 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 6.959437e-07 6.157 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 8.222501e-07 6.085 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.600841e-07 6.065 0 0
DNA Double Strand Break Response R-HSA-5693606 8.818185e-07 6.055 0 0
Defective pyroptosis R-HSA-9710421 9.782564e-07 6.010 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.066819e-06 5.972 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.067850e-06 5.971 0 0
Mitotic Anaphase R-HSA-68882 1.119958e-06 5.951 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.105938e-06 5.956 0 0
Diseases of programmed cell death R-HSA-9645723 1.069194e-06 5.971 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.183479e-06 5.927 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.194665e-06 5.923 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.228421e-06 5.911 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.262289e-06 5.899 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.447050e-06 5.840 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.159229e-06 5.666 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.320956e-06 5.634 0 0
ESR-mediated signaling R-HSA-8939211 2.763969e-06 5.558 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 2.822199e-06 5.549 0 0
Gene Silencing by RNA R-HSA-211000 2.756308e-06 5.560 0 0
Depyrimidination R-HSA-73928 2.822199e-06 5.549 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 2.937855e-06 5.532 0 0
HATs acetylate histones R-HSA-3214847 4.247093e-06 5.372 0 0
Reproduction R-HSA-1474165 4.608777e-06 5.336 0 0
Translation initiation complex formation R-HSA-72649 5.018038e-06 5.299 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 8.033628e-06 5.095 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 9.144402e-06 5.039 0 0
Cellular response to starvation R-HSA-9711097 9.260482e-06 5.033 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.008659e-05 4.996 1 0
Semaphorin interactions R-HSA-373755 1.183835e-05 4.927 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.260177e-05 4.900 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.416973e-05 4.849 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.416973e-05 4.849 0 0
Chromosome Maintenance R-HSA-73886 1.333982e-05 4.875 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.331753e-05 4.876 0 0
Ub-specific processing proteases R-HSA-5689880 1.361977e-05 4.866 0 0
Apoptosis R-HSA-109581 1.526859e-05 4.816 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.578959e-05 4.802 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.656054e-05 4.781 0 0
Deubiquitination R-HSA-5688426 1.761374e-05 4.754 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.833877e-05 4.737 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.939218e-05 4.712 0 0
Separation of Sister Chromatids R-HSA-2467813 1.946117e-05 4.711 0 0
HCMV Early Events R-HSA-9609690 1.972554e-05 4.705 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.989890e-05 4.701 0 0
Cell-Cell communication R-HSA-1500931 2.703258e-05 4.568 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.778564e-05 4.556 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 3.688904e-05 4.433 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 3.960453e-05 4.402 0 0
Processing of DNA double-strand break ends R-HSA-5693607 4.385272e-05 4.358 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.996673e-05 4.301 0 0
rRNA processing R-HSA-72312 5.330506e-05 4.273 0 0
DNA Double-Strand Break Repair R-HSA-5693532 5.353164e-05 4.271 0 0
Telomere Maintenance R-HSA-157579 5.386033e-05 4.269 0 0
RNA Polymerase I Transcription R-HSA-73864 7.055876e-05 4.151 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 7.237455e-05 4.140 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.237455e-05 4.140 0 0
Cell junction organization R-HSA-446728 7.443213e-05 4.128 0 0
NRAGE signals death through JNK R-HSA-193648 7.844647e-05 4.105 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 8.339380e-05 4.079 0 0
Base Excision Repair R-HSA-73884 8.556085e-05 4.068 0 0
L1CAM interactions R-HSA-373760 8.801852e-05 4.055 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 9.130384e-05 4.040 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 9.970574e-05 4.001 0 0
DNA Replication R-HSA-69306 1.135540e-04 3.945 0 0
Homology Directed Repair R-HSA-5693538 1.142020e-04 3.942 0 0
Amyloid fiber formation R-HSA-977225 1.157176e-04 3.937 0 0
G2/M Transition R-HSA-69275 1.172870e-04 3.931 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.193840e-04 3.923 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.242888e-04 3.906 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.247573e-04 3.904 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.247573e-04 3.904 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.268434e-04 3.897 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.431172e-04 3.844 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.484820e-04 3.828 0 0
DNA Repair R-HSA-73894 1.493280e-04 3.826 0 0
Signaling by Hippo R-HSA-2028269 1.517006e-04 3.819 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.643838e-04 3.784 0 0
G alpha (12/13) signalling events R-HSA-416482 1.847968e-04 3.733 0 0
Selenoamino acid metabolism R-HSA-2408522 1.802572e-04 3.744 0 0
Gene expression (Transcription) R-HSA-74160 1.866699e-04 3.729 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.876865e-04 3.727 0 0
Programmed Cell Death R-HSA-5357801 2.118122e-04 3.674 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.145766e-04 3.668 0 0
Chromatin modifying enzymes R-HSA-3247509 2.259462e-04 3.646 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.373917e-04 3.625 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.373917e-04 3.625 0 0
SARS-CoV-2-host interactions R-HSA-9705683 2.487519e-04 3.604 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.520801e-04 3.598 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 2.832015e-04 3.548 0 0
mRNA 3'-end processing R-HSA-72187 3.087473e-04 3.510 0 0
RNA Polymerase II Transcription R-HSA-73857 3.273617e-04 3.485 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 3.435068e-04 3.464 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 3.831493e-04 3.417 0 0
Chromatin organization R-HSA-4839726 4.283773e-04 3.368 0 0
AURKA Activation by TPX2 R-HSA-8854518 4.688439e-04 3.329 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 4.857185e-04 3.314 0 0
Viral Infection Pathways R-HSA-9824446 4.687998e-04 3.329 0 0
Gap junction trafficking and regulation R-HSA-157858 5.041905e-04 3.297 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.444150e-04 3.264 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 5.733006e-04 3.242 0 0
Activation of BH3-only proteins R-HSA-114452 5.759801e-04 3.240 0 0
Sema4D in semaphorin signaling R-HSA-400685 5.814171e-04 3.236 0 0
SARS-CoV-1 Infection R-HSA-9678108 5.824236e-04 3.235 0 0
Metalloprotease DUBs R-HSA-5689901 7.507060e-04 3.125 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 7.507060e-04 3.125 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 7.507073e-04 3.125 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 7.507073e-04 3.125 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 7.794590e-04 3.108 0 0
HCMV Infection R-HSA-9609646 8.105465e-04 3.091 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 8.386345e-04 3.076 0 0
Interleukin-12 signaling R-HSA-9020591 8.449115e-04 3.073 0 0
Selective autophagy R-HSA-9663891 8.933801e-04 3.049 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 9.159934e-04 3.038 1 1
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.035977e-03 2.985 0 0
Recycling pathway of L1 R-HSA-437239 9.858441e-04 3.006 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.098529e-03 2.959 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.098529e-03 2.959 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.134567e-03 2.945 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.147797e-03 2.940 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.154358e-03 2.938 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.176921e-03 2.929 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.215717e-03 2.915 0 0
Rap1 signalling R-HSA-392517 1.225424e-03 2.912 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.258102e-03 2.900 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.301928e-03 2.885 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.301928e-03 2.885 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.301928e-03 2.885 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.304376e-03 2.885 0 0
HCMV Late Events R-HSA-9610379 1.334823e-03 2.875 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.399397e-03 2.854 0 0
PKR-mediated signaling R-HSA-9833482 1.454499e-03 2.837 0 0
Cell-cell junction organization R-HSA-421270 1.491622e-03 2.826 0 0
Gap junction trafficking R-HSA-190828 1.606560e-03 2.794 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.707895e-03 2.768 1 0
Nuclear import of Rev protein R-HSA-180746 1.713292e-03 2.766 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.739391e-03 2.760 0 0
Post NMDA receptor activation events R-HSA-438064 1.770569e-03 2.752 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.804453e-03 2.744 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.804453e-03 2.744 0 0
Oncogene Induced Senescence R-HSA-2559585 2.082855e-03 2.681 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.082855e-03 2.681 0 0
Adherens junctions interactions R-HSA-418990 2.014165e-03 2.696 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.947730e-03 2.710 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.254363e-03 2.647 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.254363e-03 2.647 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.254363e-03 2.647 0 0
Signaling by RAS mutants R-HSA-6802949 2.254363e-03 2.647 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 2.284755e-03 2.641 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.344076e-03 2.630 1 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.379246e-03 2.624 1 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.495031e-03 2.603 0 0
TRP channels R-HSA-3295583 2.538285e-03 2.595 0 0
MAP2K and MAPK activation R-HSA-5674135 2.618250e-03 2.582 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 2.686038e-03 2.571 0 0
Generic Transcription Pathway R-HSA-212436 2.883465e-03 2.540 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 3.053409e-03 2.515 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.074448e-03 2.512 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.166635e-03 2.499 0 0
Signaling by NOTCH R-HSA-157118 3.286689e-03 2.483 0 0
Synaptic adhesion-like molecules R-HSA-8849932 3.524021e-03 2.453 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 3.566137e-03 2.448 0 0
PIP3 activates AKT signaling R-HSA-1257604 3.590248e-03 2.445 0 0
Muscle contraction R-HSA-397014 3.802570e-03 2.420 0 0
Interleukin-12 family signaling R-HSA-447115 3.829415e-03 2.417 0 0
Centrosome maturation R-HSA-380287 3.937052e-03 2.405 0 0
FOXO-mediated transcription R-HSA-9614085 4.027468e-03 2.395 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 4.036860e-03 2.394 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 4.036860e-03 2.394 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.066088e-03 2.391 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 4.548506e-03 2.342 0 0
RAF activation R-HSA-5673000 4.956032e-03 2.305 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 4.267026e-03 2.370 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 4.666682e-03 2.331 0 0
RMTs methylate histone arginines R-HSA-3214858 4.274949e-03 2.369 0 0
Signaling by VEGF R-HSA-194138 4.905012e-03 2.309 1 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 4.964892e-03 2.304 0 0
Signaling by ALK in cancer R-HSA-9700206 4.964892e-03 2.304 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 4.267026e-03 2.370 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.030926e-03 2.298 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 5.030926e-03 2.298 0 0
Regulation of endogenous retroelements R-HSA-9842860 5.447419e-03 2.264 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 5.700467e-03 2.244 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 5.727786e-03 2.242 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 5.732422e-03 2.242 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.464345e-03 2.189 1 0
Transcriptional Regulation by TP53 R-HSA-3700989 6.570197e-03 2.182 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.727591e-03 2.172 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.727591e-03 2.172 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 6.727591e-03 2.172 1 1
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 6.838990e-03 2.165 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 6.838990e-03 2.165 0 0
Signaling by RAF1 mutants R-HSA-9656223 6.883937e-03 2.162 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 6.888949e-03 2.162 0 0
Membrane Trafficking R-HSA-199991 6.973542e-03 2.157 0 0
EPH-Ephrin signaling R-HSA-2682334 7.229661e-03 2.141 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 7.690219e-03 2.114 0 0
MITF-M-dependent gene expression R-HSA-9856651 8.134198e-03 2.090 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 8.163214e-03 2.088 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 8.207181e-03 2.086 0 0
Glycolysis R-HSA-70171 8.781195e-03 2.056 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 8.863363e-03 2.052 0 0
UCH proteinases R-HSA-5689603 9.451074e-03 2.025 0 0
Interaction between L1 and Ankyrins R-HSA-445095 9.460124e-03 2.024 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 9.530260e-03 2.021 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 9.548675e-03 2.020 0 0
Gap junction degradation R-HSA-190873 9.548675e-03 2.020 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 9.548675e-03 2.020 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 9.637371e-03 2.016 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.723515e-03 2.012 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.040754e-02 1.983 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.054314e-02 1.977 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 1.082895e-02 1.965 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 1.082895e-02 1.965 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.082895e-02 1.965 0 0
Death Receptor Signaling R-HSA-73887 1.090049e-02 1.963 0 0
Receptor Mediated Mitophagy R-HSA-8934903 1.309211e-02 1.883 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.309211e-02 1.883 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.215017e-02 1.915 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.278679e-02 1.893 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.132824e-02 1.946 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.312259e-02 1.882 0 0
Interferon Signaling R-HSA-913531 1.320287e-02 1.879 0 0
Gap junction assembly R-HSA-190861 1.323446e-02 1.878 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.423538e-02 1.847 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.470187e-02 1.833 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 1.470187e-02 1.833 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.470187e-02 1.833 0 0
Kinesins R-HSA-983189 1.520913e-02 1.818 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.573931e-02 1.803 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.577692e-02 1.802 1 1
Activation of the pre-replicative complex R-HSA-68962 1.577692e-02 1.802 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 1.598849e-02 1.796 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.662532e-02 1.779 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.682522e-02 1.774 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.705708e-02 1.768 0 0
RET signaling R-HSA-8853659 1.775545e-02 1.751 1 1
GPER1 signaling R-HSA-9634597 1.785090e-02 1.748 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.785090e-02 1.748 0 0
Long-term potentiation R-HSA-9620244 1.871379e-02 1.728 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.877840e-02 1.726 0 0
Co-inhibition by PD-1 R-HSA-389948 1.897360e-02 1.722 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.933685e-02 1.714 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.933685e-02 1.714 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.933685e-02 1.714 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.933685e-02 1.714 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.933685e-02 1.714 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 2.045862e-02 1.689 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 2.061614e-02 1.686 0 0
Signaling by EGFR R-HSA-177929 2.072254e-02 1.684 0 0
Ion homeostasis R-HSA-5578775 2.072254e-02 1.684 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 2.074754e-02 1.683 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.074754e-02 1.683 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 2.074754e-02 1.683 0 0
Autophagy R-HSA-9612973 2.085233e-02 1.681 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 2.206958e-02 1.656 0 0
Regulation of PTEN localization R-HSA-8948747 2.246968e-02 1.648 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 2.246968e-02 1.648 0 0
MECP2 regulates transcription factors R-HSA-9022707 2.246968e-02 1.648 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 2.262640e-02 1.645 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.293070e-02 1.640 0 0
Nuclear Receptor transcription pathway R-HSA-383280 2.307295e-02 1.637 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.327503e-02 1.633 0 0
IRE1alpha activates chaperones R-HSA-381070 2.426385e-02 1.615 0 0
Activation of ATR in response to replication stress R-HSA-176187 2.474484e-02 1.607 0 0
Regulation of gap junction activity R-HSA-191650 2.643921e-02 1.578 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 2.643921e-02 1.578 0 0
Formation of annular gap junctions R-HSA-196025 3.034437e-02 1.518 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 2.873248e-02 1.542 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 2.873248e-02 1.542 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.873248e-02 1.542 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.840818e-02 1.547 0 0
snRNP Assembly R-HSA-191859 2.846647e-02 1.546 0 0
Metabolism of non-coding RNA R-HSA-194441 2.846647e-02 1.546 0 0
Chaperonin-mediated protein folding R-HSA-390466 2.939783e-02 1.532 0 0
Protein folding R-HSA-391251 2.635671e-02 1.579 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.551180e-02 1.593 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 2.643921e-02 1.578 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 2.873248e-02 1.542 0 0
Signaling by LTK R-HSA-9842663 2.873248e-02 1.542 0 0
Aggrephagy R-HSA-9646399 3.005271e-02 1.522 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.653562e-02 1.576 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 3.034437e-02 1.518 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.099919e-02 1.509 0 0
Specification of primordial germ cells R-HSA-9827857 3.095295e-02 1.509 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.582896e-02 1.588 0 0
FGFR2 alternative splicing R-HSA-6803529 3.104303e-02 1.508 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.104303e-02 1.508 0 0
mTORC1-mediated signalling R-HSA-166208 3.104303e-02 1.508 0 0
Signaling by ERBB2 R-HSA-1227986 3.146449e-02 1.502 1 0
Mitophagy R-HSA-5205647 3.243592e-02 1.489 0 0
Macroautophagy R-HSA-1632852 3.277538e-02 1.484 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.388696e-02 1.470 0 0
Hemostasis R-HSA-109582 3.487305e-02 1.458 1 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 3.578948e-02 1.446 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 3.578948e-02 1.446 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 3.684276e-02 1.434 0 0
Signalling to ERKs R-HSA-187687 3.684276e-02 1.434 0 0
PKA activation in glucagon signalling R-HSA-164378 3.710029e-02 1.431 0 0
Ephrin signaling R-HSA-3928664 3.710029e-02 1.431 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 3.710029e-02 1.431 0 0
Polo-like kinase mediated events R-HSA-156711 3.710029e-02 1.431 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 3.710029e-02 1.431 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.890751e-02 1.410 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 3.890751e-02 1.410 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.890882e-02 1.410 0 0
GP1b-IX-V activation signalling R-HSA-430116 3.965484e-02 1.402 0 0
Calcineurin activates NFAT R-HSA-2025928 3.965484e-02 1.402 0 0
Interleukin-37 signaling R-HSA-9008059 3.972639e-02 1.401 0 0
Response of endothelial cells to shear stress R-HSA-9860931 4.017598e-02 1.396 0 0
Defective Base Excision Repair Associated with OGG1 R-HSA-9656249 4.062111e-02 1.391 0 0
Oligomerization of connexins into connexons R-HSA-190704 4.062111e-02 1.391 0 0
Transport of connexins along the secretory pathway R-HSA-190827 4.062111e-02 1.391 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 4.062111e-02 1.391 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 4.062111e-02 1.391 0 0
Breakdown of the nuclear lamina R-HSA-352238 4.062111e-02 1.391 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 4.092402e-02 1.388 0 0
Regulation of TP53 Degradation R-HSA-6804757 4.164200e-02 1.380 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.187124e-02 1.378 0 0
Glucose metabolism R-HSA-70326 4.212059e-02 1.376 0 0
Deadenylation of mRNA R-HSA-429947 4.227333e-02 1.374 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 4.227333e-02 1.374 0 0
MTOR signalling R-HSA-165159 4.255374e-02 1.371 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 4.327959e-02 1.364 0 0
Cardiac conduction R-HSA-5576891 4.342280e-02 1.362 0 0
MAPK family signaling cascades R-HSA-5683057 4.367622e-02 1.360 0 0
CRMPs in Sema3A signaling R-HSA-399956 4.382645e-02 1.358 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 4.528819e-02 1.344 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 4.528819e-02 1.344 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.553585e-02 1.342 0 0
Unfolded Protein Response (UPR) R-HSA-381119 4.653590e-02 1.332 0 0
Voltage gated Potassium channels R-HSA-1296072 4.684546e-02 1.329 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 5.027661e-02 1.299 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 5.041554e-02 1.297 0 0
Signaling by Leptin R-HSA-2586552 5.041554e-02 1.297 0 0
Diseases of mitotic cell cycle R-HSA-9675126 5.133727e-02 1.290 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 5.160083e-02 1.287 0 0
S Phase R-HSA-69242 5.236273e-02 1.281 0 0
Signaling by NTRKs R-HSA-166520 5.236273e-02 1.281 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 5.246335e-02 1.280 0 0
DCC mediated attractive signaling R-HSA-418885 5.286062e-02 1.277 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 5.286062e-02 1.277 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 6.746677e-02 1.171 0 0
Regulation of TP53 Expression R-HSA-6804754 6.746677e-02 1.171 0 0
Diseases of Cellular Senescence R-HSA-9630747 6.746677e-02 1.171 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 6.746677e-02 1.171 0 0
Diseases of cellular response to stress R-HSA-9675132 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 6.746677e-02 1.171 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 6.746677e-02 1.171 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 6.746677e-02 1.171 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 5.384618e-02 1.269 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 5.384618e-02 1.269 0 0
CREB phosphorylation R-HSA-199920 7.111521e-02 1.148 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 7.111521e-02 1.148 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 7.111521e-02 1.148 0 0
Phosphorylation of the APC/C R-HSA-176412 6.289765e-02 1.201 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 6.912588e-02 1.160 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 6.353978e-02 1.197 0 0
Striated Muscle Contraction R-HSA-390522 6.493473e-02 1.188 0 0
Regulation of TP53 Activity R-HSA-5633007 6.457558e-02 1.190 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 5.384618e-02 1.269 0 0
Prolonged ERK activation events R-HSA-169893 6.289765e-02 1.201 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 6.140608e-02 1.212 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 5.384618e-02 1.269 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 5.845695e-02 1.233 0 0
RAF/MAP kinase cascade R-HSA-5673001 6.164631e-02 1.210 0 0
Rab regulation of trafficking R-HSA-9007101 6.832929e-02 1.165 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 5.819751e-02 1.235 0 0
Effects of PIP2 hydrolysis R-HSA-114508 6.493473e-02 1.188 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 6.353978e-02 1.197 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 5.727745e-02 1.242 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 5.998218e-02 1.222 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.184569e-02 1.144 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 7.204753e-02 1.142 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 7.213066e-02 1.142 0 0
Activation of RAC1 R-HSA-428540 7.622087e-02 1.118 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.903047e-02 1.102 0 0
Negative regulation of MAPK pathway R-HSA-5675221 7.922282e-02 1.101 0 0
DARPP-32 events R-HSA-180024 8.076482e-02 1.093 0 0
Platelet calcium homeostasis R-HSA-418360 8.076482e-02 1.093 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 8.122667e-02 1.090 0 0
SARS-CoV Infections R-HSA-9679506 8.244714e-02 1.084 0 0
HIV Life Cycle R-HSA-162587 8.313712e-02 1.080 0 0
Ion channel transport R-HSA-983712 8.335841e-02 1.079 0 0
Ion transport by P-type ATPases R-HSA-936837 8.428257e-02 1.074 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 8.536797e-02 1.069 0 0
Signaling by WNT R-HSA-195721 8.572113e-02 1.067 1 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 8.594795e-02 1.066 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 8.656112e-02 1.063 1 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 8.700460e-02 1.060 0 0
Netrin mediated repulsion signals R-HSA-418886 9.052998e-02 1.043 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 9.052998e-02 1.043 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 9.052998e-02 1.043 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 9.055697e-02 1.043 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 9.117840e-02 1.040 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 9.117840e-02 1.040 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 9.117840e-02 1.040 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.527463e-02 1.021 0 0
MET interacts with TNS proteins R-HSA-8875513 9.854878e-02 1.006 0 0
MET activates PTPN11 R-HSA-8865999 9.854878e-02 1.006 0 0
Chaperone Mediated Autophagy R-HSA-9613829 9.891975e-02 1.005 0 0
Platelet sensitization by LDL R-HSA-432142 9.891975e-02 1.005 0 0
Neutrophil degranulation R-HSA-6798695 9.900450e-02 1.004 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.000801e-01 1.000 0 0
Defective OGG1 Substrate Binding R-HSA-9656255 1.000801e-01 1.000 0 0
Defective OGG1 Localization R-HSA-9657050 1.000801e-01 1.000 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 1.000801e-01 1.000 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 1.000801e-01 1.000 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 1.000801e-01 1.000 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 1.000801e-01 1.000 0 0
Host Interactions of HIV factors R-HSA-162909 1.003465e-01 0.998 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.010868e-01 0.995 0 0
Neurodegenerative Diseases R-HSA-8863678 1.010868e-01 0.995 0 0
Netrin-1 signaling R-HSA-373752 1.038802e-01 0.983 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.038802e-01 0.983 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.063752e-01 0.973 1 0
Protein ubiquitination R-HSA-8852135 1.063752e-01 0.973 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.074180e-01 0.969 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 1.074180e-01 0.969 0 0
Frs2-mediated activation R-HSA-170968 1.074180e-01 0.969 0 0
Neurexins and neuroligins R-HSA-6794361 1.078513e-01 0.967 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.105960e-01 0.956 0 0
G1/S Transition R-HSA-69206 1.109943e-01 0.955 0 0
Type I hemidesmosome assembly R-HSA-446107 1.118764e-01 0.951 0 0
Adrenoceptors R-HSA-390696 1.118764e-01 0.951 0 0
The NLRP3 inflammasome R-HSA-844456 1.128132e-01 0.948 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 1.129670e-01 0.947 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.129670e-01 0.947 0 0
HDMs demethylate histones R-HSA-3214842 1.132068e-01 0.946 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.140372e-01 0.943 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.179314e-01 0.928 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.187828e-01 0.925 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 1.224598e-01 0.912 0 0
Integrin signaling R-HSA-354192 1.224598e-01 0.912 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 1.224598e-01 0.912 0 0
Nuclear RNA decay R-HSA-9930044 1.224598e-01 0.912 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.224598e-01 0.912 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.224598e-01 0.912 0 0
Platelet homeostasis R-HSA-418346 1.262772e-01 0.899 0 0
tRNA processing in the nucleus R-HSA-6784531 1.273013e-01 0.895 0 0
Co-inhibition by CTLA4 R-HSA-389513 1.275862e-01 0.894 0 0
Nephrin family interactions R-HSA-373753 1.275862e-01 0.894 0 0
Defective OGG1 Substrate Processing R-HSA-9656256 1.901494e-01 0.721 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 1.901494e-01 0.721 0 0
Defective ACTH causes obesity and POMCD R-HSA-5579031 1.901494e-01 0.721 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.901494e-01 0.721 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 1.901494e-01 0.721 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 1.901494e-01 0.721 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 1.901494e-01 0.721 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.327513e-01 0.877 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 1.327513e-01 0.877 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 1.327513e-01 0.877 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 1.327513e-01 0.877 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 1.327513e-01 0.877 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 1.327513e-01 0.877 0 0
IRS activation R-HSA-74713 1.691393e-01 0.772 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 1.691393e-01 0.772 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 1.691393e-01 0.772 0 0
ARMS-mediated activation R-HSA-170984 1.349229e-01 0.870 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 1.349229e-01 0.870 0 0
Binding and entry of HIV virion R-HSA-173107 1.594301e-01 0.797 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.594301e-01 0.797 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.594301e-01 0.797 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.851579e-01 0.732 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.433982e-01 0.843 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.433982e-01 0.843 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.629420e-01 0.788 0 0
Phase 4 - resting membrane potential R-HSA-5576886 1.629420e-01 0.788 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 1.629420e-01 0.788 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.395139e-01 0.855 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.395139e-01 0.855 0 0
HIV elongation arrest and recovery R-HSA-167287 1.536408e-01 0.813 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.536408e-01 0.813 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.343287e-01 0.872 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.836636e-01 0.736 0 0
G alpha (z) signalling events R-HSA-418597 1.348132e-01 0.870 1 1
Early Phase of HIV Life Cycle R-HSA-162594 1.431901e-01 0.844 0 0
IGF1R signaling cascade R-HSA-2428924 1.453123e-01 0.838 0 0
DNA Damage Bypass R-HSA-73893 1.534759e-01 0.814 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.804029e-01 0.744 0 0
Signal amplification R-HSA-392518 1.467406e-01 0.833 0 0
Signal attenuation R-HSA-74749 1.594301e-01 0.797 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 1.431901e-01 0.844 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 1.766676e-01 0.753 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 1.547919e-01 0.810 0 0
Nucleotide Excision Repair R-HSA-5696398 1.802415e-01 0.744 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 1.343287e-01 0.872 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.944191e-01 0.711 0 0
Signaling by FGFR2 R-HSA-5654738 1.448894e-01 0.839 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 1.349229e-01 0.870 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.602441e-01 0.795 0 0
Dopamine receptors R-HSA-390651 1.327513e-01 0.877 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.749542e-01 0.757 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.846694e-01 0.734 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 1.757282e-01 0.755 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.534759e-01 0.814 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.534759e-01 0.814 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 1.691393e-01 0.772 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 1.833792e-01 0.737 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.836636e-01 0.736 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 1.361464e-01 0.866 0 0
Regulation of CDH1 Function R-HSA-9764561 1.545916e-01 0.811 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.448894e-01 0.839 0 0
Translation R-HSA-72766 1.498522e-01 0.824 0 0
Inhibition of PKR R-HSA-169131 1.901494e-01 0.721 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.327513e-01 0.877 0 0
MTF1 activates gene expression R-HSA-5660489 1.327513e-01 0.877 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 1.691393e-01 0.772 0 0
Unwinding of DNA R-HSA-176974 1.349229e-01 0.870 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 1.629420e-01 0.788 0 0
TBC/RABGAPs R-HSA-8854214 1.753741e-01 0.756 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.361464e-01 0.866 0 0
Potassium Channels R-HSA-1296071 1.665976e-01 0.778 0 0
Adaptive Immune System R-HSA-1280218 1.893191e-01 0.723 0 0
Syndecan interactions R-HSA-3000170 1.944191e-01 0.711 1 1
Protein methylation R-HSA-8876725 1.433982e-01 0.843 0 0
Ca-dependent events R-HSA-111996 1.630061e-01 0.788 1 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.349229e-01 0.870 1 1
PECAM1 interactions R-HSA-210990 1.851579e-01 0.732 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.850289e-01 0.733 0 0
RAB geranylgeranylation R-HSA-8873719 1.867774e-01 0.729 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.630061e-01 0.788 0 0
Calmodulin induced events R-HSA-111933 1.731000e-01 0.762 1 1
CaM pathway R-HSA-111997 1.731000e-01 0.762 1 0
Immune System R-HSA-168256 1.527973e-01 0.816 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 1.691393e-01 0.772 0 0
FLT3 Signaling R-HSA-9607240 1.395549e-01 0.855 0 0
Infectious disease R-HSA-5663205 1.360132e-01 0.866 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.594301e-01 0.797 0 0
Co-inhibition by BTLA R-HSA-9927353 1.691393e-01 0.772 0 0
NrCAM interactions R-HSA-447038 1.691393e-01 0.772 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.595702e-01 0.797 0 0
Growth hormone receptor signaling R-HSA-982772 1.944191e-01 0.711 0 0
Other semaphorin interactions R-HSA-416700 1.433982e-01 0.843 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 1.349229e-01 0.870 0 0
EGFR downregulation R-HSA-182971 1.994793e-01 0.700 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 1.996019e-01 0.700 0 0
Smooth Muscle Contraction R-HSA-445355 2.000889e-01 0.699 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 2.012940e-01 0.696 0 0
DAG and IP3 signaling R-HSA-1489509 2.012940e-01 0.696 1 0
TP53 Regulates Metabolic Genes R-HSA-5628897 2.014268e-01 0.696 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 2.023091e-01 0.694 1 0
Stimuli-sensing channels R-HSA-2672351 2.058622e-01 0.686 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.069334e-01 0.684 0 0
PKB-mediated events R-HSA-109703 2.069334e-01 0.684 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.069334e-01 0.684 0 0
Phosphorylation of Emi1 R-HSA-176417 2.069334e-01 0.684 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.069334e-01 0.684 0 0
PDE3B signalling R-HSA-165160 2.069334e-01 0.684 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.069334e-01 0.684 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 2.069334e-01 0.684 0 0
Diseases of Base Excision Repair R-HSA-9605308 2.069334e-01 0.684 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.069334e-01 0.684 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 2.118713e-01 0.674 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 2.118713e-01 0.674 0 0
Signaling by GSK3beta mutants R-HSA-5339716 2.118713e-01 0.674 0 0
Integration of provirus R-HSA-162592 2.118713e-01 0.674 0 0
Thromboxane signalling through TP receptor R-HSA-428930 2.127593e-01 0.672 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.127593e-01 0.672 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 2.127593e-01 0.672 0 0
G alpha (s) signalling events R-HSA-418555 2.136530e-01 0.670 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 2.148009e-01 0.668 0 0
Signaling by TGFBR3 R-HSA-9839373 2.148009e-01 0.668 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 2.150002e-01 0.668 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.264872e-01 0.645 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 2.264872e-01 0.645 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.264872e-01 0.645 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.264872e-01 0.645 0 0
GAB1 signalosome R-HSA-180292 2.264872e-01 0.645 0 0
PKA activation R-HSA-163615 2.264872e-01 0.645 0 0
Tight junction interactions R-HSA-420029 2.316206e-01 0.635 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 2.325019e-01 0.634 0 0
PI and PC transport between ER and Golgi membranes R-HSA-1483196 2.712088e-01 0.567 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 2.712088e-01 0.567 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 2.712088e-01 0.567 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 2.712088e-01 0.567 0 0
SMAD4 MH2 Domain Mutants in Cancer R-HSA-3311021 2.712088e-01 0.567 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.712088e-01 0.567 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 2.712088e-01 0.567 0 0
IKBKB deficiency causes SCID R-HSA-5602636 2.712088e-01 0.567 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.712088e-01 0.567 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.712088e-01 0.567 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 2.712088e-01 0.567 0 0
SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-3315487 2.712088e-01 0.567 0 0
Loss of Function of SMAD4 in Cancer R-HSA-3304347 2.712088e-01 0.567 0 0
Defective GFPT1 causes CMSTA1 R-HSA-4085023 2.712088e-01 0.567 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 2.712088e-01 0.567 0 0
MPS IIID - Sanfilippo syndrome D R-HSA-2206305 2.712088e-01 0.567 0 0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 2.712088e-01 0.567 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 3.441592e-01 0.463 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 3.441592e-01 0.463 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 3.441592e-01 0.463 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 3.441592e-01 0.463 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.441592e-01 0.463 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 3.441592e-01 0.463 0 0
Potassium transport channels R-HSA-1296067 3.441592e-01 0.463 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 3.441592e-01 0.463 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 3.441592e-01 0.463 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 2.454881e-01 0.610 0 0
STAT5 Activation R-HSA-9645135 2.454881e-01 0.610 0 0
G2/M DNA replication checkpoint R-HSA-69478 2.454881e-01 0.610 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 2.454881e-01 0.610 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 2.842731e-01 0.546 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 2.842731e-01 0.546 0 0
SOS-mediated signalling R-HSA-112412 2.842731e-01 0.546 0 0
Axonal growth stimulation R-HSA-209563 4.098112e-01 0.387 0 0
TFAP2 (AP-2) family regulates transcription of other transcription factors R-HSA-8866906 4.098112e-01 0.387 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 4.098112e-01 0.387 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 4.098112e-01 0.387 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 4.098112e-01 0.387 0 0
Classical Kir channels R-HSA-1296053 4.098112e-01 0.387 0 0
Adrenaline signalling through Alpha-2 adrenergic receptor R-HSA-392023 4.098112e-01 0.387 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 4.098112e-01 0.387 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 2.393447e-01 0.621 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 2.393447e-01 0.621 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 2.393447e-01 0.621 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 2.393447e-01 0.621 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 2.393447e-01 0.621 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 2.393447e-01 0.621 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 3.228563e-01 0.491 0 0
FGFR1b ligand binding and activation R-HSA-190370 3.228563e-01 0.491 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 2.673648e-01 0.573 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 2.673648e-01 0.573 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 2.673648e-01 0.573 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 2.673648e-01 0.573 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.489326e-01 0.604 0 0
Lipophagy R-HSA-9613354 3.608898e-01 0.443 0 0
WNT mediated activation of DVL R-HSA-201688 3.608898e-01 0.443 0 0
ALK mutants bind TKIs R-HSA-9700645 3.608898e-01 0.443 0 0
HCN channels R-HSA-1296061 4.688947e-01 0.329 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 4.688947e-01 0.329 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.688947e-01 0.329 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 4.688947e-01 0.329 0 0
Signaling by MAP2K mutants R-HSA-9652169 4.688947e-01 0.329 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 4.688947e-01 0.329 0 0
Erythropoietin activates RAS R-HSA-9027284 3.242654e-01 0.489 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 3.242654e-01 0.489 0 0
MAPK3 (ERK1) activation R-HSA-110056 3.980973e-01 0.400 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.980973e-01 0.400 0 0
2-LTR circle formation R-HSA-164843 3.980973e-01 0.400 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 3.980973e-01 0.400 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 3.527959e-01 0.452 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.185172e-01 0.497 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.185172e-01 0.497 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 2.906444e-01 0.537 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 2.670726e-01 0.573 0 0
Termination of translesion DNA synthesis R-HSA-5656169 3.109047e-01 0.507 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 3.811743e-01 0.419 0 0
Phase 2 - plateau phase R-HSA-5576893 3.811743e-01 0.419 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 4.342631e-01 0.362 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 4.342631e-01 0.362 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 4.342631e-01 0.362 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 4.342631e-01 0.362 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.313468e-01 0.480 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.657582e-01 0.437 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.210040e-01 0.493 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 4.092670e-01 0.388 0 0
Trafficking of AMPA receptors R-HSA-399719 3.519069e-01 0.454 1 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.893545e-01 0.410 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 3.577936e-01 0.446 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 4.369564e-01 0.360 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.931377e-01 0.405 1 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.763028e-01 0.424 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.048712e-01 0.516 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 4.360929e-01 0.360 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 4.641405e-01 0.333 0 0
Dual Incision in GG-NER R-HSA-5696400 4.341399e-01 0.362 0 0
Orc1 removal from chromatin R-HSA-68949 4.461301e-01 0.351 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.461301e-01 0.351 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.629048e-01 0.335 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.629048e-01 0.335 0 0
Signaling by NOTCH2 R-HSA-1980145 2.670726e-01 0.573 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 3.385094e-01 0.470 0 0
Specification of the neural plate border R-HSA-9834899 2.489326e-01 0.604 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.466436e-01 0.608 0 0
HIV Transcription Elongation R-HSA-167169 3.763028e-01 0.424 0 0
Formation of definitive endoderm R-HSA-9823730 2.718239e-01 0.566 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 4.423940e-01 0.354 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 2.509344e-01 0.600 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 2.466436e-01 0.608 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.608898e-01 0.443 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.763028e-01 0.424 0 0
PTEN Regulation R-HSA-6807070 2.952883e-01 0.530 0 0
Signaling by FGFR R-HSA-190236 2.658100e-01 0.575 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.454881e-01 0.610 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 3.811743e-01 0.419 1 1
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 3.893545e-01 0.410 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 4.590923e-01 0.338 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 3.980973e-01 0.400 1 1
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.953758e-01 0.403 0 0
PI3K Cascade R-HSA-109704 4.123366e-01 0.385 0 0
COPI-mediated anterograde transport R-HSA-6807878 4.545580e-01 0.342 0 0
Regulation of mitotic cell cycle R-HSA-453276 4.535610e-01 0.343 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 4.535610e-01 0.343 0 0
Cyclin D associated events in G1 R-HSA-69231 3.111954e-01 0.507 0 0
G1 Phase R-HSA-69236 3.111954e-01 0.507 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.489326e-01 0.604 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 2.842731e-01 0.546 0 0
Signalling to RAS R-HSA-167044 2.950533e-01 0.530 0 0
Regulation of CDH11 function R-HSA-9762292 3.980973e-01 0.400 0 0
PI3K/AKT activation R-HSA-198203 3.980973e-01 0.400 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.342631e-01 0.362 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 4.092670e-01 0.388 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 3.577936e-01 0.446 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 3.113911e-01 0.507 0 0
Switching of origins to a post-replicative state R-HSA-69052 3.522245e-01 0.453 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.670726e-01 0.573 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 3.798740e-01 0.420 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.424679e-01 0.465 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.342631e-01 0.362 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 3.060504e-01 0.514 0 0
Signaling by FGFR4 R-HSA-5654743 4.501241e-01 0.347 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 2.842731e-01 0.546 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.489326e-01 0.604 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.811743e-01 0.419 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 2.784457e-01 0.555 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 3.313468e-01 0.480 0 0
Translesion Synthesis by POLH R-HSA-110320 4.641405e-01 0.333 0 0
HIV Infection R-HSA-162906 2.421316e-01 0.616 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.948307e-01 0.404 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 3.421167e-01 0.466 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.509344e-01 0.600 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 4.590923e-01 0.338 0 0
TCR signaling R-HSA-202403 4.119977e-01 0.385 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.388753e-01 0.358 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 4.092670e-01 0.388 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 4.641405e-01 0.333 1 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 2.947198e-01 0.531 0 0
Apoptotic factor-mediated response R-HSA-111471 4.369564e-01 0.360 0 0
Developmental Cell Lineages R-HSA-9734767 4.400164e-01 0.357 0 0
Interleukin-2 signaling R-HSA-9020558 4.342631e-01 0.362 0 0
Regulation of KIT signaling R-HSA-1433559 2.957328e-01 0.529 1 1
Opioid Signalling R-HSA-111885 3.315315e-01 0.479 1 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.228563e-01 0.491 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 4.688947e-01 0.329 0 0
p38MAPK events R-HSA-171007 3.242654e-01 0.489 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 4.092670e-01 0.388 0 0
DNA strand elongation R-HSA-69190 3.725234e-01 0.429 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.931377e-01 0.405 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 4.641405e-01 0.333 0 0
Signaling by SCF-KIT R-HSA-1433557 2.947198e-01 0.531 1 1
G-protein mediated events R-HSA-112040 3.946476e-01 0.404 1 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 3.893545e-01 0.410 0 0
Signaling by TGFB family members R-HSA-9006936 4.182736e-01 0.379 0 0
Vesicle-mediated transport R-HSA-5653656 2.844343e-01 0.546 0 0
Integration of energy metabolism R-HSA-163685 4.473201e-01 0.349 1 0
Neuronal System R-HSA-112316 2.389659e-01 0.622 1 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 4.545580e-01 0.342 0 0
Mismatch Repair R-HSA-5358508 4.369564e-01 0.360 0 0
Signaling by PTK6 R-HSA-8848021 3.360484e-01 0.474 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 3.360484e-01 0.474 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 2.848205e-01 0.545 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 3.278373e-01 0.484 0 0
Signaling by NOTCH1 R-HSA-1980143 3.937716e-01 0.405 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.712088e-01 0.567 0 0
Manipulation of host energy metabolism R-HSA-9636667 2.712088e-01 0.567 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 3.441592e-01 0.463 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 3.441592e-01 0.463 0 0
Regulation of cortical dendrite branching R-HSA-8985801 3.441592e-01 0.463 0 0
MET activates STAT3 R-HSA-8875791 4.098112e-01 0.387 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 3.228563e-01 0.491 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.608898e-01 0.443 0 0
Electric Transmission Across Gap Junctions R-HSA-112303 4.688947e-01 0.329 0 0
Transmission across Electrical Synapses R-HSA-112307 4.688947e-01 0.329 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 3.242654e-01 0.489 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 3.242654e-01 0.489 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 3.527959e-01 0.452 0 0
Disorders of Developmental Biology R-HSA-9675151 3.811743e-01 0.419 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 3.811743e-01 0.419 0 0
Ionotropic activity of kainate receptors R-HSA-451306 4.342631e-01 0.362 0 0
Signaling by APC mutants R-HSA-4839744 4.342631e-01 0.362 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.657582e-01 0.437 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 3.134308e-01 0.504 1 1
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 4.681861e-01 0.330 0 0
FLT3 signaling in disease R-HSA-9682385 3.028133e-01 0.519 0 0
Co-stimulation by CD28 R-HSA-389356 3.784130e-01 0.422 0 0
Generation of second messenger molecules R-HSA-202433 3.763028e-01 0.424 0 0
PLC beta mediated events R-HSA-112043 3.072978e-01 0.512 1 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 3.106673e-01 0.508 0 0
NGF-stimulated transcription R-HSA-9031628 3.784130e-01 0.422 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 2.906444e-01 0.537 0 0
MyD88-independent TLR4 cascade R-HSA-166166 3.106673e-01 0.508 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 3.542447e-01 0.451 0 0
Aquaporin-mediated transport R-HSA-445717 4.423940e-01 0.354 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 3.722998e-01 0.429 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.608898e-01 0.443 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.931377e-01 0.405 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 3.481701e-01 0.458 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 3.661375e-01 0.436 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 3.661375e-01 0.436 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 3.661375e-01 0.436 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.185172e-01 0.497 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 4.128243e-01 0.384 1 1
Hedgehog 'off' state R-HSA-5610787 3.901665e-01 0.409 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 2.842731e-01 0.546 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 2.842731e-01 0.546 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 3.228563e-01 0.491 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.608898e-01 0.443 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 4.688947e-01 0.329 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 3.527959e-01 0.452 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 3.811743e-01 0.419 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 4.342631e-01 0.362 0 0
Inflammasomes R-HSA-622312 2.906444e-01 0.537 0 0
TGFBR3 expression R-HSA-9839394 4.128243e-01 0.384 0 0
Signal transduction by L1 R-HSA-445144 2.718239e-01 0.566 0 0
Spry regulation of FGF signaling R-HSA-1295596 3.242654e-01 0.489 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 3.313468e-01 0.480 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 3.216088e-01 0.493 0 0
Platelet degranulation R-HSA-114608 3.328832e-01 0.478 0 0
Cilium Assembly R-HSA-5617833 3.651658e-01 0.438 0 0
Signaling by NOTCH3 R-HSA-9012852 3.481701e-01 0.458 0 0
Signaling by NOTCH4 R-HSA-9013694 2.526311e-01 0.598 0 0
DSCAM interactions R-HSA-376172 3.441592e-01 0.463 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 2.842731e-01 0.546 0 0
Intracellular oxygen transport R-HSA-8981607 4.098112e-01 0.387 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 4.098112e-01 0.387 0 0
Alpha-defensins R-HSA-1462054 3.228563e-01 0.491 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.957328e-01 0.529 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 3.608898e-01 0.443 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.608898e-01 0.443 0 0
NADE modulates death signalling R-HSA-205025 4.688947e-01 0.329 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 4.688947e-01 0.329 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.688947e-01 0.329 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 3.980973e-01 0.400 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 3.811743e-01 0.419 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 4.342631e-01 0.362 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 3.328823e-01 0.478 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.489326e-01 0.604 0 0
Downstream signal transduction R-HSA-186763 3.519069e-01 0.454 0 0
Pexophagy R-HSA-9664873 3.980973e-01 0.400 0 0
Sensory processing of sound R-HSA-9659379 3.145398e-01 0.502 0 0
Mitochondrial calcium ion transport R-HSA-8949215 3.185172e-01 0.497 0 0
Histamine receptors R-HSA-390650 4.098112e-01 0.387 0 0
Suppression of apoptosis R-HSA-9635465 4.342631e-01 0.362 0 0
Amine ligand-binding receptors R-HSA-375280 4.683340e-01 0.329 0 0
Regulation of IFNG signaling R-HSA-877312 2.393447e-01 0.621 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 2.496173e-01 0.603 0 0
Prostanoid ligand receptors R-HSA-391908 4.342631e-01 0.362 0 0
Triglyceride metabolism R-HSA-8979227 4.109747e-01 0.386 0 0
FasL/ CD95L signaling R-HSA-75157 4.098112e-01 0.387 0 0
Signal regulatory protein family interactions R-HSA-391160 2.957328e-01 0.529 0 0
Signaling by Interleukins R-HSA-449147 2.494727e-01 0.603 0 0
Signaling by ALK R-HSA-201556 3.577936e-01 0.446 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.590923e-01 0.338 0 0
Inositol phosphate metabolism R-HSA-1483249 3.322120e-01 0.479 0 0
Triglyceride catabolism R-HSA-163560 3.028133e-01 0.519 0 0
Tandem pore domain potassium channels R-HSA-1296346 3.980973e-01 0.400 0 0
ChREBP activates metabolic gene expression R-HSA-163765 4.342631e-01 0.362 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.648641e-01 0.333 0 0
Interleukin-7 signaling R-HSA-1266695 4.128243e-01 0.384 0 0
HDL assembly R-HSA-8963896 2.957328e-01 0.529 0 0
Maturation of hRSV A proteins R-HSA-9828806 4.590923e-01 0.338 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 3.577936e-01 0.446 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.692232e-01 0.329 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 4.692232e-01 0.329 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 4.692232e-01 0.329 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.692232e-01 0.329 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.692232e-01 0.329 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.692232e-01 0.329 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.692232e-01 0.329 0 0
Signaling by AMER1 mutants R-HSA-4839748 4.692232e-01 0.329 0 0
Signaling by AXIN mutants R-HSA-4839735 4.692232e-01 0.329 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.692232e-01 0.329 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 4.692232e-01 0.329 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 4.692232e-01 0.329 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 4.745077e-01 0.324 0 0
RNA Polymerase III Transcription R-HSA-74158 4.745077e-01 0.324 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 4.745077e-01 0.324 0 0
RUNX2 regulates bone development R-HSA-8941326 4.745077e-01 0.324 0 0
Regulation of insulin secretion R-HSA-422356 4.796481e-01 0.319 1 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 4.816544e-01 0.317 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.817609e-01 0.317 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 4.817609e-01 0.317 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 4.846416e-01 0.315 0 0
Signaling by FGFR3 R-HSA-5654741 4.863762e-01 0.313 0 0
Synthesis of DNA R-HSA-69239 4.866942e-01 0.313 0 0
Insulin receptor signalling cascade R-HSA-74751 4.890057e-01 0.311 0 0
Ovarian tumor domain proteases R-HSA-5689896 4.943418e-01 0.306 0 0
Signaling by ERBB4 R-HSA-1236394 4.971821e-01 0.303 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 4.986244e-01 0.302 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 4.995987e-01 0.301 0 0
MET activates RAS signaling R-HSA-8851805 5.028564e-01 0.299 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 5.028564e-01 0.299 0 0
IRAK1 recruits IKK complex R-HSA-937039 5.028564e-01 0.299 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 5.028564e-01 0.299 0 0
Pervasive developmental disorders R-HSA-9005895 5.028564e-01 0.299 0 0
Disorders of Nervous System Development R-HSA-9697154 5.028564e-01 0.299 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 5.028564e-01 0.299 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 5.028564e-01 0.299 0 0
Interleukin-15 signaling R-HSA-8983432 5.028564e-01 0.299 0 0
Signaling by Erythropoietin R-HSA-9006335 5.040436e-01 0.298 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 5.040436e-01 0.298 0 0
Late endosomal microautophagy R-HSA-9615710 5.040436e-01 0.298 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 5.040436e-01 0.298 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 5.040436e-01 0.298 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 5.040436e-01 0.298 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 5.040436e-01 0.298 0 0
Glucagon-type ligand receptors R-HSA-420092 5.040436e-01 0.298 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 5.040436e-01 0.298 0 0
Diseases of DNA repair R-HSA-9675135 5.042197e-01 0.297 0 0
Parasitic Infection Pathways R-HSA-9824443 5.056000e-01 0.296 0 0
Leishmania infection R-HSA-9658195 5.056000e-01 0.296 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 5.104900e-01 0.292 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.124219e-01 0.290 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 5.124219e-01 0.290 0 0
Signaling by FGFR1 R-HSA-5654736 5.124219e-01 0.290 0 0
MET promotes cell motility R-HSA-8875878 5.138904e-01 0.289 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 5.166559e-01 0.287 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 5.166559e-01 0.287 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 5.166559e-01 0.287 0 0
Basigin interactions R-HSA-210991 5.166559e-01 0.287 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 5.218357e-01 0.282 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 5.218357e-01 0.282 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 5.220666e-01 0.282 0 0
Activation of AMPA receptors R-HSA-399710 5.220666e-01 0.282 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 5.220666e-01 0.282 0 0
G2 Phase R-HSA-68911 5.220666e-01 0.282 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 5.220666e-01 0.282 0 0
Defective F9 activation R-HSA-9673221 5.220666e-01 0.282 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 5.220666e-01 0.282 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 5.220666e-01 0.282 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 5.220666e-01 0.282 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 5.220666e-01 0.282 0 0
PTK6 Down-Regulation R-HSA-8849472 5.220666e-01 0.282 0 0
Activation of AKT2 R-HSA-165158 5.220666e-01 0.282 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 5.220666e-01 0.282 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 5.220666e-01 0.282 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 5.220666e-01 0.282 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 5.220666e-01 0.282 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 5.258917e-01 0.279 0 0
IRS-mediated signalling R-HSA-112399 5.285786e-01 0.277 0 0
PI Metabolism R-HSA-1483255 5.290674e-01 0.276 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 5.333745e-01 0.273 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 5.350783e-01 0.272 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 5.350783e-01 0.272 0 0
Formation of axial mesoderm R-HSA-9796292 5.350783e-01 0.272 0 0
FGFR1c ligand binding and activation R-HSA-190373 5.350783e-01 0.272 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 5.350783e-01 0.272 0 0
Maturation of nucleoprotein R-HSA-9683610 5.350783e-01 0.272 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 5.350783e-01 0.272 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.350783e-01 0.272 0 0
Intraflagellar transport R-HSA-5620924 5.391979e-01 0.268 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 5.418522e-01 0.266 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 5.418522e-01 0.266 0 0
Signaling by PDGFR in disease R-HSA-9671555 5.418522e-01 0.266 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 5.472626e-01 0.262 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 5.519947e-01 0.258 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 5.519947e-01 0.258 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 5.519947e-01 0.258 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 5.532268e-01 0.257 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 5.571230e-01 0.254 0 0
Removal of the Flap Intermediate R-HSA-69166 5.658342e-01 0.247 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 5.658342e-01 0.247 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 5.658342e-01 0.247 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 5.658342e-01 0.247 0 0
Prolactin receptor signaling R-HSA-1170546 5.658342e-01 0.247 0 0
Malate-aspartate shuttle R-HSA-9856872 5.658342e-01 0.247 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 5.658342e-01 0.247 0 0
Zinc transporters R-HSA-435354 5.658342e-01 0.247 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.658342e-01 0.247 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 5.662712e-01 0.247 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 5.662712e-01 0.247 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 5.662712e-01 0.247 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 5.662712e-01 0.247 0 0
G0 and Early G1 R-HSA-1538133 5.681195e-01 0.246 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 5.681195e-01 0.246 0 0
Plus-strand DNA synthesis R-HSA-164525 5.699179e-01 0.244 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 5.699179e-01 0.244 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 5.699179e-01 0.244 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 5.699179e-01 0.244 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 5.699179e-01 0.244 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 5.699179e-01 0.244 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 5.699179e-01 0.244 0 0
NGF-independant TRKA activation R-HSA-187024 5.699179e-01 0.244 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 5.699179e-01 0.244 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.699179e-01 0.244 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 5.699179e-01 0.244 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 5.699179e-01 0.244 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 5.699179e-01 0.244 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 5.699179e-01 0.244 0 0
TRAIL signaling R-HSA-75158 5.699179e-01 0.244 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 5.699179e-01 0.244 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.757089e-01 0.240 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.757089e-01 0.240 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.757089e-01 0.240 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.757089e-01 0.240 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.757089e-01 0.240 0 0
Organelle biogenesis and maintenance R-HSA-1852241 5.801888e-01 0.236 0 0
MHC class II antigen presentation R-HSA-2132295 5.826226e-01 0.235 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 5.834614e-01 0.234 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 5.884313e-01 0.230 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.884313e-01 0.230 0 0
Cardiogenesis R-HSA-9733709 5.884313e-01 0.230 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 5.884313e-01 0.230 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 5.885829e-01 0.230 0 0
Signaling by FGFR1 in disease R-HSA-5655302 5.885829e-01 0.230 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 5.898741e-01 0.229 0 0
MAP kinase activation R-HSA-450294 5.909131e-01 0.228 0 0
Interferon gamma signaling R-HSA-877300 5.929596e-01 0.227 0 0
SHC1 events in EGFR signaling R-HSA-180336 5.950947e-01 0.225 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 5.950947e-01 0.225 0 0
Processive synthesis on the lagging strand R-HSA-69183 5.950947e-01 0.225 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 5.950947e-01 0.225 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 5.950947e-01 0.225 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.950947e-01 0.225 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 6.056568e-01 0.218 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 6.058386e-01 0.218 0 0
Signaling by PDGF R-HSA-186797 6.058386e-01 0.218 0 0
Miscellaneous transport and binding events R-HSA-5223345 6.081720e-01 0.216 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 6.126319e-01 0.213 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 6.126319e-01 0.213 0 0
Plasma lipoprotein assembly R-HSA-8963898 6.126319e-01 0.213 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 6.129808e-01 0.213 0 0
Signaling by LTK in cancer R-HSA-9842640 6.129808e-01 0.213 0 0
Erythropoietin activates STAT5 R-HSA-9027283 6.129808e-01 0.213 0 0
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors R-HSA-629587 6.129808e-01 0.213 0 0
Uncoating of the HIV Virion R-HSA-162585 6.129808e-01 0.213 0 0
Autointegration results in viral DNA circles R-HSA-177539 6.129808e-01 0.213 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 6.129808e-01 0.213 0 0
MET Receptor Activation R-HSA-6806942 6.129808e-01 0.213 0 0
Abacavir transmembrane transport R-HSA-2161517 6.129808e-01 0.213 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 6.129808e-01 0.213 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 6.129808e-01 0.213 0 0
NADPH regeneration R-HSA-389542 6.129808e-01 0.213 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 6.129808e-01 0.213 0 0
Lipid particle organization R-HSA-8964572 6.129808e-01 0.213 0 0
Nef and signal transduction R-HSA-164944 6.129808e-01 0.213 0 0
Interleukin-1 family signaling R-HSA-446652 6.192802e-01 0.208 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 6.228509e-01 0.206 1 1
Regulation of NF-kappa B signaling R-HSA-9758274 6.228509e-01 0.206 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 6.228509e-01 0.206 0 0
Differentiation of T cells R-HSA-9945266 6.228509e-01 0.206 0 0
Atorvastatin ADME R-HSA-9754706 6.228509e-01 0.206 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 6.273207e-01 0.203 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 6.273207e-01 0.203 0 0
Signaling by Insulin receptor R-HSA-74752 6.330098e-01 0.199 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 6.336542e-01 0.198 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 6.345242e-01 0.198 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 6.345242e-01 0.198 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 6.345242e-01 0.198 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 6.348021e-01 0.197 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 6.447572e-01 0.191 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 6.447572e-01 0.191 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 6.458611e-01 0.190 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 6.458611e-01 0.190 0 0
PERK regulates gene expression R-HSA-381042 6.458611e-01 0.190 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 6.491107e-01 0.188 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 6.491107e-01 0.188 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 6.491107e-01 0.188 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 6.491107e-01 0.188 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 6.491107e-01 0.188 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 6.491107e-01 0.188 0 0
Synthesis of PG R-HSA-1483148 6.491107e-01 0.188 0 0
Response to metal ions R-HSA-5660526 6.491107e-01 0.188 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 6.517343e-01 0.186 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 6.517343e-01 0.186 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 6.517343e-01 0.186 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 6.517343e-01 0.186 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 6.517343e-01 0.186 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 6.517343e-01 0.186 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 6.517343e-01 0.186 0 0
IFNG signaling activates MAPKs R-HSA-9732724 6.517343e-01 0.186 0 0
PTK6 Expression R-HSA-8849473 6.517343e-01 0.186 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 6.517343e-01 0.186 0 0
Disinhibition of SNARE formation R-HSA-114516 6.517343e-01 0.186 1 1
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 6.517343e-01 0.186 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 6.517343e-01 0.186 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 6.517343e-01 0.186 0 0
DAG1 core M1 glycosylations R-HSA-8932506 6.517343e-01 0.186 0 0
Recycling of eIF2:GDP R-HSA-72731 6.517343e-01 0.186 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 6.517343e-01 0.186 0 0
TRIF-mediated programmed cell death R-HSA-2562578 6.517343e-01 0.186 0 0
Activation of TRKA receptors R-HSA-187015 6.517343e-01 0.186 0 0
CHL1 interactions R-HSA-447041 6.517343e-01 0.186 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 6.517343e-01 0.186 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 6.518677e-01 0.186 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 6.553082e-01 0.184 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 6.555386e-01 0.183 0 0
Myogenesis R-HSA-525793 6.555386e-01 0.183 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 6.555386e-01 0.183 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 6.555386e-01 0.183 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 6.555386e-01 0.183 0 0
Disease R-HSA-1643685 6.568058e-01 0.183 0 0
GPVI-mediated activation cascade R-HSA-114604 6.637811e-01 0.178 0 0
G1/S-Specific Transcription R-HSA-69205 6.637811e-01 0.178 0 0
Signaling by Hedgehog R-HSA-5358351 6.647810e-01 0.177 0 0
ER to Golgi Anterograde Transport R-HSA-199977 6.648533e-01 0.177 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 6.665099e-01 0.176 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 6.679618e-01 0.175 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.698048e-01 0.174 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.723348e-01 0.172 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.723348e-01 0.172 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 6.738955e-01 0.171 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 6.738955e-01 0.171 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 6.738955e-01 0.171 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 6.738955e-01 0.171 0 0
Sulfide oxidation to sulfate R-HSA-1614517 6.738955e-01 0.171 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 6.738955e-01 0.171 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 6.738955e-01 0.171 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 6.751583e-01 0.171 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 6.751583e-01 0.171 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 6.756695e-01 0.170 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 6.756695e-01 0.170 0 0
Cristae formation R-HSA-8949613 6.756695e-01 0.170 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 6.756695e-01 0.170 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 6.756695e-01 0.170 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 6.756695e-01 0.170 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 6.758749e-01 0.170 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 6.810726e-01 0.167 0 0
GPCR downstream signalling R-HSA-388396 6.815524e-01 0.167 1 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.832945e-01 0.165 0 0
Leishmania phagocytosis R-HSA-9664417 6.832945e-01 0.165 0 0
Parasite infection R-HSA-9664407 6.832945e-01 0.165 0 0
Reverse Transcription of HIV RNA R-HSA-162589 6.866092e-01 0.163 0 0
Minus-strand DNA synthesis R-HSA-164516 6.866092e-01 0.163 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 6.866092e-01 0.163 0 0
DAG1 core M2 glycosylations R-HSA-8932504 6.866092e-01 0.163 0 0
phospho-PLA2 pathway R-HSA-111995 6.866092e-01 0.163 0 0
Highly calcium permeable nicotinic acetylcholine receptors R-HSA-629597 6.866092e-01 0.163 0 0
MET receptor recycling R-HSA-8875656 6.866092e-01 0.163 0 0
Activation of RAS in B cells R-HSA-1169092 6.866092e-01 0.163 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 6.866092e-01 0.163 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.866092e-01 0.163 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 6.866092e-01 0.163 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 6.866092e-01 0.163 0 0
Sodium/Proton exchangers R-HSA-425986 6.866092e-01 0.163 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 6.866092e-01 0.163 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 6.866092e-01 0.163 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 6.876556e-01 0.163 0 0
Transcription of the HIV genome R-HSA-167172 6.889017e-01 0.162 0 0
Circadian clock R-HSA-9909396 6.933064e-01 0.159 0 0
Dual incision in TC-NER R-HSA-6782135 6.946026e-01 0.158 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 6.946026e-01 0.158 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 6.949174e-01 0.158 0 0
Formation of the Early Elongation Complex R-HSA-113418 6.949174e-01 0.158 0 0
Telomere Extension By Telomerase R-HSA-171319 6.949174e-01 0.158 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 6.949174e-01 0.158 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 6.949174e-01 0.158 0 0
Pyroptosis R-HSA-5620971 6.949174e-01 0.158 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 6.972372e-01 0.157 1 1
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.972372e-01 0.157 0 0
FGFR1 ligand binding and activation R-HSA-190242 6.972372e-01 0.157 0 0
Tie2 Signaling R-HSA-210993 6.972372e-01 0.157 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.972372e-01 0.157 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 6.972372e-01 0.157 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 6.977312e-01 0.156 0 0
Toll-like Receptor Cascades R-HSA-168898 7.059235e-01 0.151 0 0
Extension of Telomeres R-HSA-180786 7.080425e-01 0.150 0 0
Signaling by MET R-HSA-6806834 7.084660e-01 0.150 0 0
Stabilization of p53 R-HSA-69541 7.137555e-01 0.146 0 0
Interleukin-17 signaling R-HSA-448424 7.139272e-01 0.146 0 0
Downstream TCR signaling R-HSA-202424 7.151750e-01 0.146 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 7.179937e-01 0.144 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 7.179937e-01 0.144 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 7.179937e-01 0.144 0 0
p75NTR regulates axonogenesis R-HSA-193697 7.179937e-01 0.144 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 7.179937e-01 0.144 0 0
MAPK1 (ERK2) activation R-HSA-112411 7.179937e-01 0.144 0 0
Regulation of signaling by NODAL R-HSA-1433617 7.179937e-01 0.144 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 7.179937e-01 0.144 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 7.179937e-01 0.144 0 0
Interleukin-1 processing R-HSA-448706 7.179937e-01 0.144 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 7.179937e-01 0.144 0 0
Cellular response to mitochondrial stress R-HSA-9840373 7.179937e-01 0.144 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 7.191764e-01 0.143 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 7.191764e-01 0.143 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 7.191764e-01 0.143 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 7.191764e-01 0.143 0 0
Maturation of nucleoprotein R-HSA-9694631 7.191764e-01 0.143 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 7.191764e-01 0.143 0 0
Transmission across Chemical Synapses R-HSA-112315 7.256654e-01 0.139 1 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 7.259195e-01 0.139 0 0
Diseases of Immune System R-HSA-5260271 7.291474e-01 0.137 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 7.291474e-01 0.137 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 7.291474e-01 0.137 0 0
Interleukin-2 family signaling R-HSA-451927 7.291474e-01 0.137 0 0
Regulation of RAS by GAPs R-HSA-5658442 7.306460e-01 0.136 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 7.307920e-01 0.136 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.307920e-01 0.136 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.307920e-01 0.136 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 7.397597e-01 0.131 0 0
Negative regulation of MET activity R-HSA-6807004 7.397597e-01 0.131 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 7.397597e-01 0.131 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 7.397597e-01 0.131 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 7.397597e-01 0.131 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 7.397597e-01 0.131 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 7.397597e-01 0.131 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 7.397597e-01 0.131 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 7.397597e-01 0.131 0 0
Signaling by NODAL R-HSA-1181150 7.397597e-01 0.131 0 0
Protein hydroxylation R-HSA-9629569 7.397597e-01 0.131 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 7.397597e-01 0.131 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 7.430610e-01 0.129 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 7.439826e-01 0.128 0 0
Mitochondrial protein import R-HSA-1268020 7.459056e-01 0.127 0 0
Heme signaling R-HSA-9707616 7.459056e-01 0.127 0 0
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors R-HSA-629594 7.462369e-01 0.127 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.462369e-01 0.127 0 0
Formation of apoptosome R-HSA-111458 7.462369e-01 0.127 0 0
Regulation of the apoptosome activity R-HSA-9627069 7.462369e-01 0.127 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 7.462369e-01 0.127 0 0
DNA replication initiation R-HSA-68952 7.462369e-01 0.127 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 7.462369e-01 0.127 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 7.462369e-01 0.127 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 7.462369e-01 0.127 0 0
Formation of intermediate mesoderm R-HSA-9761174 7.462369e-01 0.127 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 7.462369e-01 0.127 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 7.462369e-01 0.127 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 7.462369e-01 0.127 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 7.462369e-01 0.127 0 0
Josephin domain DUBs R-HSA-5689877 7.462369e-01 0.127 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 7.462369e-01 0.127 0 0
Budding and maturation of HIV virion R-HSA-162588 7.474435e-01 0.126 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.474435e-01 0.126 0 0
Cargo concentration in the ER R-HSA-5694530 7.474435e-01 0.126 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 7.568255e-01 0.121 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 7.580533e-01 0.120 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 7.580533e-01 0.120 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 7.580533e-01 0.120 0 0
G-protein activation R-HSA-202040 7.590387e-01 0.120 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 7.590387e-01 0.120 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 7.590387e-01 0.120 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 7.590387e-01 0.120 0 0
Lagging Strand Synthesis R-HSA-69186 7.590387e-01 0.120 0 0
ERK/MAPK targets R-HSA-198753 7.590387e-01 0.120 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 7.590387e-01 0.120 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 7.590387e-01 0.120 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 7.626156e-01 0.118 0 0
Inwardly rectifying K+ channels R-HSA-1296065 7.632601e-01 0.117 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.632601e-01 0.117 0 0
Signaling by WNT in cancer R-HSA-4791275 7.632601e-01 0.117 0 0
Regulation of PTEN stability and activity R-HSA-8948751 7.691790e-01 0.114 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.691790e-01 0.114 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 7.691790e-01 0.114 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 7.703924e-01 0.113 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 7.715830e-01 0.113 0 0
DAG1 core M3 glycosylations R-HSA-8932505 7.716530e-01 0.113 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 7.716530e-01 0.113 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 7.716530e-01 0.113 0 0
FGFR2b ligand binding and activation R-HSA-190377 7.716530e-01 0.113 0 0
FGFRL1 modulation of FGFR1 signaling R-HSA-5658623 7.716530e-01 0.113 0 0
vRNA Synthesis R-HSA-192814 7.716530e-01 0.113 0 0
Bicarbonate transporters R-HSA-425381 7.716530e-01 0.113 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 7.716530e-01 0.113 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 7.716530e-01 0.113 0 0
LGI-ADAM interactions R-HSA-5682910 7.716530e-01 0.113 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 7.716530e-01 0.113 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 7.770680e-01 0.110 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 7.770680e-01 0.110 0 0
Attachment and Entry R-HSA-9694614 7.770680e-01 0.110 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 7.770680e-01 0.110 0 0
Assembly Of The HIV Virion R-HSA-175474 7.770680e-01 0.110 0 0
G-protein beta:gamma signalling R-HSA-397795 7.782624e-01 0.109 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 7.782624e-01 0.109 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.782624e-01 0.109 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 7.782624e-01 0.109 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 7.810487e-01 0.107 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 7.813002e-01 0.107 0 0
Response of Mtb to phagocytosis R-HSA-9637690 7.845106e-01 0.105 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 7.905440e-01 0.102 0 0
Resolution of D-Loop Structures R-HSA-5693537 7.924728e-01 0.101 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 7.924728e-01 0.101 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 7.924728e-01 0.101 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 7.939046e-01 0.100 0 0
Notch-HLH transcription pathway R-HSA-350054 7.939046e-01 0.100 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 7.939046e-01 0.100 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 7.939046e-01 0.100 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.939046e-01 0.100 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 7.939046e-01 0.100 0 0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy R-HSA-9857377 7.939046e-01 0.100 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 7.939046e-01 0.100 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 7.945248e-01 0.100 0 0
Presynaptic nicotinic acetylcholine receptors R-HSA-622323 7.945248e-01 0.100 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 7.945248e-01 0.100 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 7.945248e-01 0.100 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 7.945248e-01 0.100 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 7.945248e-01 0.100 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 7.945248e-01 0.100 0 0
NF-kB is activated and signals survival R-HSA-209560 7.945248e-01 0.100 0 0
ERKs are inactivated R-HSA-202670 7.945248e-01 0.100 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 7.945248e-01 0.100 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 7.945248e-01 0.100 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 7.968483e-01 0.099 0 0
Interferon alpha/beta signaling R-HSA-909733 7.975317e-01 0.098 0 0
TNF signaling R-HSA-75893 8.033647e-01 0.095 0 0
Innate Immune System R-HSA-168249 8.050252e-01 0.094 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.059159e-01 0.094 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.059159e-01 0.094 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 8.086098e-01 0.092 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 8.086098e-01 0.092 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 8.096065e-01 0.092 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 8.096065e-01 0.092 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 8.096065e-01 0.092 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 8.096065e-01 0.092 0 0
Biosynthesis of maresins R-HSA-9018682 8.096065e-01 0.092 0 0
Regulated Necrosis R-HSA-5218859 8.106842e-01 0.091 0 0
Mitochondrial biogenesis R-HSA-1592230 8.127096e-01 0.090 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 8.151070e-01 0.089 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 8.151070e-01 0.089 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 8.151070e-01 0.089 0 0
Repression of WNT target genes R-HSA-4641265 8.151070e-01 0.089 0 0
GRB2 events in EGFR signaling R-HSA-179812 8.151070e-01 0.089 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 8.151070e-01 0.089 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.151070e-01 0.089 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 8.151070e-01 0.089 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 8.151070e-01 0.089 0 0
Polymerase switching R-HSA-69091 8.151070e-01 0.089 0 0
VLDLR internalisation and degradation R-HSA-8866427 8.151070e-01 0.089 0 0
Leading Strand Synthesis R-HSA-69109 8.151070e-01 0.089 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 8.151070e-01 0.089 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 8.151070e-01 0.089 0 0
Estrogen biosynthesis R-HSA-193144 8.151070e-01 0.089 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 8.151070e-01 0.089 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.186175e-01 0.087 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.198095e-01 0.086 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 8.198095e-01 0.086 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 8.201085e-01 0.086 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 8.238406e-01 0.084 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 8.242320e-01 0.084 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 8.242320e-01 0.084 0 0
Complex III assembly R-HSA-9865881 8.242320e-01 0.084 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 8.267989e-01 0.083 0 0
COPII-mediated vesicle transport R-HSA-204005 8.291576e-01 0.081 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.304632e-01 0.081 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 8.306045e-01 0.081 0 0
Interleukin-1 signaling R-HSA-9020702 8.330491e-01 0.079 0 0
Regulation of beta-cell development R-HSA-186712 8.334130e-01 0.079 0 0
Acetylcholine binding and downstream events R-HSA-181431 8.336285e-01 0.079 0 0
Adenylate cyclase activating pathway R-HSA-170660 8.336285e-01 0.079 0 0
Postsynaptic nicotinic acetylcholine receptors R-HSA-622327 8.336285e-01 0.079 0 0
FGFR2c ligand binding and activation R-HSA-190375 8.336285e-01 0.079 0 0
FGFR4 ligand binding and activation R-HSA-190322 8.336285e-01 0.079 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 8.336285e-01 0.079 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 8.336285e-01 0.079 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 8.336285e-01 0.079 0 0
Mtb iron assimilation by chelation R-HSA-1222449 8.336285e-01 0.079 0 0
FGFR3 mutant receptor activation R-HSA-2033514 8.336285e-01 0.079 0 0
Processing of SMDT1 R-HSA-8949664 8.336285e-01 0.079 0 0
CD28 dependent Vav1 pathway R-HSA-389359 8.336285e-01 0.079 0 0
Interleukin-6 signaling R-HSA-1059683 8.336285e-01 0.079 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 8.336285e-01 0.079 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 8.336285e-01 0.079 0 0
Signaling by GPCR R-HSA-372790 8.340026e-01 0.079 1 0
FRS-mediated FGFR1 signaling R-HSA-5654693 8.378391e-01 0.077 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 8.378391e-01 0.077 0 0
G protein gated Potassium channels R-HSA-1296059 8.378391e-01 0.077 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 8.378391e-01 0.077 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 8.378391e-01 0.077 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 8.378391e-01 0.077 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 8.378391e-01 0.077 0 0
Formation of the nephric duct R-HSA-9830364 8.378391e-01 0.077 0 0
Metal ion SLC transporters R-HSA-425410 8.405871e-01 0.075 0 0
Degradation of DVL R-HSA-4641258 8.419045e-01 0.075 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 8.425563e-01 0.074 0 0
G alpha (q) signalling events R-HSA-416476 8.427505e-01 0.074 1 0
trans-Golgi Network Vesicle Budding R-HSA-199992 8.461607e-01 0.073 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.484405e-01 0.071 0 0
Degradation of CDH1 R-HSA-9766229 8.501981e-01 0.070 0 0
NRIF signals cell death from the nucleus R-HSA-205043 8.502957e-01 0.070 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 8.502957e-01 0.070 0 0
FGFR3c ligand binding and activation R-HSA-190372 8.502957e-01 0.070 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 8.502957e-01 0.070 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 8.502957e-01 0.070 0 0
Hydrolysis of LPC R-HSA-1483115 8.502957e-01 0.070 0 0
Biosynthesis of protectins R-HSA-9018681 8.502957e-01 0.070 0 0
cGMP effects R-HSA-418457 8.502957e-01 0.070 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 8.502957e-01 0.070 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.502957e-01 0.070 0 0
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661 8.502957e-01 0.070 0 0
Acyl chain remodeling of CL R-HSA-1482798 8.502957e-01 0.070 0 0
P2Y receptors R-HSA-417957 8.502957e-01 0.070 0 0
MET activates PTK2 signaling R-HSA-8874081 8.504851e-01 0.070 0 0
Signaling by EGFR in Cancer R-HSA-1643713 8.504851e-01 0.070 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 8.504851e-01 0.070 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.525455e-01 0.069 0 0
NCAM signaling for neurite out-growth R-HSA-375165 8.596020e-01 0.066 0 0
Signaling by FGFR in disease R-HSA-1226099 8.617603e-01 0.065 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 8.622258e-01 0.064 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 8.622258e-01 0.064 0 0
Triglyceride biosynthesis R-HSA-75109 8.622258e-01 0.064 0 0
Insulin processing R-HSA-264876 8.622258e-01 0.064 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.625558e-01 0.064 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 8.652940e-01 0.063 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 8.652940e-01 0.063 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 8.652940e-01 0.063 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 8.652940e-01 0.063 0 0
G beta:gamma signalling through BTK R-HSA-8964315 8.652940e-01 0.063 0 0
Translesion synthesis by REV1 R-HSA-110312 8.652940e-01 0.063 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 8.652940e-01 0.063 0 0
Signaling by Activin R-HSA-1502540 8.652940e-01 0.063 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 8.652940e-01 0.063 0 0
FGFR3 ligand binding and activation R-HSA-190239 8.652940e-01 0.063 0 0
Synthesis of 12-eicosatetraenoic acid derivatives R-HSA-2142712 8.652940e-01 0.063 0 0
p75NTR signals via NF-kB R-HSA-193639 8.652940e-01 0.063 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 8.652940e-01 0.063 0 0
Formation of the anterior neural plate R-HSA-9823739 8.652940e-01 0.063 0 0
DNA Damage Reversal R-HSA-73942 8.652940e-01 0.063 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 8.679513e-01 0.062 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 8.719636e-01 0.060 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 8.719636e-01 0.060 0 0
Glycogen metabolism R-HSA-8982491 8.719636e-01 0.060 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 8.731158e-01 0.059 0 0
Insulin receptor recycling R-HSA-77387 8.731158e-01 0.059 0 0
Prednisone ADME R-HSA-9757110 8.731158e-01 0.059 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.740080e-01 0.058 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 8.749758e-01 0.058 0 0
Translesion synthesis by POLI R-HSA-5656121 8.787905e-01 0.056 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 8.787905e-01 0.056 0 0
Killing mechanisms R-HSA-9664420 8.787905e-01 0.056 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 8.787905e-01 0.056 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 8.787905e-01 0.056 0 0
Activation of SMO R-HSA-5635838 8.787905e-01 0.056 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 8.787905e-01 0.056 0 0
Attachment and Entry R-HSA-9678110 8.787905e-01 0.056 0 0
Negative regulation of FLT3 R-HSA-9706369 8.787905e-01 0.056 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 8.807970e-01 0.055 0 0
Cellular response to hypoxia R-HSA-1234174 8.822512e-01 0.054 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 8.832075e-01 0.054 0 0
mRNA Capping R-HSA-72086 8.832075e-01 0.054 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 8.832075e-01 0.054 0 0
Regulation of gene expression in beta cells R-HSA-210745 8.832075e-01 0.054 0 0
Post-translational protein phosphorylation R-HSA-8957275 8.867413e-01 0.052 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.890835e-01 0.051 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 8.890835e-01 0.051 0 0
Intra-Golgi traffic R-HSA-6811438 8.890835e-01 0.051 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 8.909354e-01 0.050 0 0
Translesion synthesis by POLK R-HSA-5655862 8.909354e-01 0.050 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 8.909354e-01 0.050 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 8.909354e-01 0.050 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 8.909354e-01 0.050 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 8.909354e-01 0.050 0 0
Vitamin B6 activation to pyridoxal phosphate R-HSA-964975 8.909354e-01 0.050 0 0
Passive transport by Aquaporins R-HSA-432047 8.909354e-01 0.050 0 0
Fibronectin matrix formation R-HSA-1566977 8.909354e-01 0.050 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 8.909354e-01 0.050 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 8.909354e-01 0.050 0 0
DAP12 signaling R-HSA-2424491 8.925517e-01 0.049 0 0
Activation of GABAB receptors R-HSA-991365 8.968505e-01 0.047 0 0
GABA B receptor activation R-HSA-977444 8.968505e-01 0.047 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 8.968505e-01 0.047 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.011966e-01 0.045 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 9.011966e-01 0.045 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 9.018641e-01 0.045 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 9.018641e-01 0.045 0 0
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770 9.018641e-01 0.045 0 0
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265 9.018641e-01 0.045 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 9.018641e-01 0.045 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 9.018641e-01 0.045 0 0
Uptake and function of anthrax toxins R-HSA-5210891 9.018641e-01 0.045 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.045959e-01 0.044 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.091887e-01 0.041 0 0
Synthesis of PA R-HSA-1483166 9.107399e-01 0.041 0 0
Surfactant metabolism R-HSA-5683826 9.109312e-01 0.041 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 9.116983e-01 0.040 0 0
Activated point mutants of FGFR2 R-HSA-2033519 9.116983e-01 0.040 0 0
Presynaptic function of Kainate receptors R-HSA-500657 9.116983e-01 0.040 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 9.116983e-01 0.040 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.116983e-01 0.040 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 9.116983e-01 0.040 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 9.130580e-01 0.040 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.172960e-01 0.037 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.172960e-01 0.037 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.176844e-01 0.037 0 0
SLC transporter disorders R-HSA-5619102 9.205212e-01 0.036 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 9.205475e-01 0.036 0 0
Pyrimidine biosynthesis R-HSA-500753 9.205475e-01 0.036 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 9.205475e-01 0.036 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.205475e-01 0.036 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 9.205475e-01 0.036 0 0
Regulation of signaling by CBL R-HSA-912631 9.205475e-01 0.036 0 0
Diseases of hemostasis R-HSA-9671793 9.205475e-01 0.036 0 0
Other interleukin signaling R-HSA-449836 9.205475e-01 0.036 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.232433e-01 0.035 0 0
Regulation of TNFR1 signaling R-HSA-5357905 9.232433e-01 0.035 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.233878e-01 0.035 0 0
GABA receptor activation R-HSA-977443 9.271096e-01 0.033 0 0
tRNA Aminoacylation R-HSA-379724 9.271096e-01 0.033 0 0
Ca2+ pathway R-HSA-4086398 9.279318e-01 0.032 1 1
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.285104e-01 0.032 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 9.285104e-01 0.032 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 9.285104e-01 0.032 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.285104e-01 0.032 0 0
Keratan sulfate degradation R-HSA-2022857 9.285104e-01 0.032 0 0
Synthesis of PC R-HSA-1483191 9.287963e-01 0.032 0 0
NOD1/2 Signaling Pathway R-HSA-168638 9.296761e-01 0.032 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.296761e-01 0.032 0 0
Cellular response to chemical stress R-HSA-9711123 9.303690e-01 0.031 0 0
Gluconeogenesis R-HSA-70263 9.339779e-01 0.030 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 9.356756e-01 0.029 0 0
FGFR2 ligand binding and activation R-HSA-190241 9.356756e-01 0.029 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 9.356756e-01 0.029 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 9.356756e-01 0.029 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 9.356756e-01 0.029 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 9.356756e-01 0.029 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.356756e-01 0.029 0 0
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896 9.356756e-01 0.029 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.356756e-01 0.029 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 9.356756e-01 0.029 0 0
Gastrulation R-HSA-9758941 9.357580e-01 0.029 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.361026e-01 0.029 0 0
Pyruvate metabolism R-HSA-70268 9.379641e-01 0.028 0 0
Potential therapeutics for SARS R-HSA-9679191 9.386834e-01 0.027 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.407222e-01 0.027 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.408167e-01 0.026 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.408167e-01 0.026 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.413279e-01 0.026 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.413279e-01 0.026 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.421231e-01 0.026 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 9.421231e-01 0.026 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.421231e-01 0.026 0 0
ER-Phagosome pathway R-HSA-1236974 9.450509e-01 0.025 0 0
Adipogenesis R-HSA-9843745 9.456085e-01 0.024 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.457370e-01 0.024 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.461621e-01 0.024 0 0
Integrin cell surface interactions R-HSA-216083 9.477392e-01 0.023 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.479246e-01 0.023 0 0
Signaling by KIT in disease R-HSA-9669938 9.479246e-01 0.023 0 0
Biosynthesis of D-series resolvins R-HSA-9018676 9.479246e-01 0.023 0 0
Ethanol oxidation R-HSA-71384 9.479246e-01 0.023 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.483149e-01 0.023 0 0
Elastic fibre formation R-HSA-1566948 9.502660e-01 0.022 0 0
Purine salvage R-HSA-74217 9.502660e-01 0.022 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 9.502660e-01 0.022 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.514086e-01 0.022 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.514086e-01 0.022 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.531449e-01 0.021 0 0
Synthesis of UDP-N-acetyl-glucosamine R-HSA-446210 9.531449e-01 0.021 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 9.531449e-01 0.021 0 0
Organic anion transport by SLCO transporters R-HSA-879518 9.531449e-01 0.021 0 0
Carnitine shuttle R-HSA-200425 9.531449e-01 0.021 0 0
Interleukin-20 family signaling R-HSA-8854691 9.531449e-01 0.021 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.544326e-01 0.020 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.550988e-01 0.020 0 0
CYP2E1 reactions R-HSA-211999 9.578422e-01 0.019 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.578422e-01 0.019 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.578422e-01 0.019 0 0
Interleukin-6 family signaling R-HSA-6783589 9.578422e-01 0.019 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 9.582640e-01 0.019 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.582640e-01 0.019 0 0
RSV-host interactions R-HSA-9833110 9.602603e-01 0.018 0 0
tRNA processing R-HSA-72306 9.605674e-01 0.017 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.617854e-01 0.017 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.617854e-01 0.017 0 0
Acyl chain remodelling of PS R-HSA-1482801 9.620688e-01 0.017 0 0
Hyaluronan degradation R-HSA-2160916 9.620688e-01 0.017 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.620688e-01 0.017 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 9.650206e-01 0.015 0 0
HIV Transcription Initiation R-HSA-167161 9.650206e-01 0.015 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 9.650206e-01 0.015 0 0
Translation of Structural Proteins R-HSA-9683701 9.650206e-01 0.015 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.658719e-01 0.015 0 0
Urea cycle R-HSA-70635 9.658719e-01 0.015 0 0
Abacavir ADME R-HSA-2161522 9.658719e-01 0.015 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.658719e-01 0.015 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.688163e-01 0.014 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.692939e-01 0.014 0 0
Synthesis of PE R-HSA-1483213 9.692939e-01 0.014 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.693805e-01 0.014 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 9.707185e-01 0.013 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.707185e-01 0.013 0 0
Defensins R-HSA-1461973 9.707185e-01 0.013 0 0
Metabolism of proteins R-HSA-392499 9.713812e-01 0.013 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.720050e-01 0.012 0 0
Pyrimidine salvage R-HSA-73614 9.723730e-01 0.012 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.730749e-01 0.012 0 0
Proteasome assembly R-HSA-9907900 9.732206e-01 0.012 0 0
DAP12 interactions R-HSA-2172127 9.732206e-01 0.012 0 0
Thyroxine biosynthesis R-HSA-209968 9.751434e-01 0.011 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 9.751434e-01 0.011 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.751434e-01 0.011 0 0
Biosynthesis of EPA-derived SPMs R-HSA-9018679 9.751434e-01 0.011 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 9.755156e-01 0.011 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.755156e-01 0.011 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.755156e-01 0.011 0 0
Somitogenesis R-HSA-9824272 9.755156e-01 0.011 0 0
Fanconi Anemia Pathway R-HSA-6783310 9.755156e-01 0.011 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.761604e-01 0.010 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.761604e-01 0.010 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.776198e-01 0.010 1 1
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.776362e-01 0.010 0 0
Neurotransmitter clearance R-HSA-112311 9.776362e-01 0.010 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.776362e-01 0.010 0 0
Mucopolysaccharidoses R-HSA-2206281 9.776362e-01 0.010 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.795484e-01 0.009 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.798791e-01 0.009 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.798791e-01 0.009 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.798791e-01 0.009 0 0
PCP/CE pathway R-HSA-4086400 9.800074e-01 0.009 1 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.809608e-01 0.008 0 0
Xenobiotics R-HSA-211981 9.813104e-01 0.008 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.814562e-01 0.008 0 0
DAG1 glycosylations R-HSA-8931838 9.818972e-01 0.008 0 0
HS-GAG degradation R-HSA-2024096 9.818972e-01 0.008 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.824549e-01 0.008 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.829338e-01 0.007 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.829338e-01 0.007 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.837130e-01 0.007 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.844157e-01 0.007 0 0
Protein localization R-HSA-9609507 9.852686e-01 0.006 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.853468e-01 0.006 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.853468e-01 0.006 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.853468e-01 0.006 0 0
Heme degradation R-HSA-189483 9.853468e-01 0.006 0 0
Extracellular matrix organization R-HSA-1474244 9.855750e-01 0.006 1 0
Hedgehog ligand biogenesis R-HSA-5358346 9.857721e-01 0.006 0 0
The phototransduction cascade R-HSA-2514856 9.857721e-01 0.006 1 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.861772e-01 0.006 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.863164e-01 0.006 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.868167e-01 0.006 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.868167e-01 0.006 0 0
eNOS activation R-HSA-203615 9.868167e-01 0.006 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.868167e-01 0.006 0 0
Hyaluronan metabolism R-HSA-2142845 9.868167e-01 0.006 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.868167e-01 0.006 0 0
Post-translational protein modification R-HSA-597592 9.874023e-01 0.006 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.879467e-01 0.005 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.881393e-01 0.005 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.881393e-01 0.005 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.881393e-01 0.005 0 0
Regulation of Apoptosis R-HSA-169911 9.881393e-01 0.005 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.881393e-01 0.005 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.881487e-01 0.005 0 0
Nucleotide biosynthesis R-HSA-8956320 9.881487e-01 0.005 0 0
HS-GAG biosynthesis R-HSA-2022928 9.893293e-01 0.005 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.893293e-01 0.005 0 0
ECM proteoglycans R-HSA-3000178 9.895142e-01 0.005 0 0
Hedgehog 'on' state R-HSA-5632684 9.895142e-01 0.005 0 0
G alpha (i) signalling events R-HSA-418594 9.897560e-01 0.004 1 0
Formation of the cornified envelope R-HSA-6809371 9.901107e-01 0.004 0 0
Degradation of AXIN R-HSA-4641257 9.903999e-01 0.004 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.903999e-01 0.004 0 0
NCAM1 interactions R-HSA-419037 9.903999e-01 0.004 0 0
Collagen chain trimerization R-HSA-8948216 9.903999e-01 0.004 0 0
Metabolism of folate and pterines R-HSA-196757 9.903999e-01 0.004 0 0
ABC-family proteins mediated transport R-HSA-382556 9.908374e-01 0.004 0 0
Peptide ligand-binding receptors R-HSA-375276 9.909759e-01 0.004 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.910011e-01 0.004 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 9.910096e-01 0.004 1 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.913632e-01 0.004 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.922299e-01 0.003 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.922299e-01 0.003 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.922299e-01 0.003 0 0
Iron uptake and transport R-HSA-917937 9.925063e-01 0.003 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.928545e-01 0.003 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.929461e-01 0.003 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.930096e-01 0.003 0 0
Translation of Structural Proteins R-HSA-9694635 9.936740e-01 0.003 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.937111e-01 0.003 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.937111e-01 0.003 0 0
Maturation of spike protein R-HSA-9694548 9.937111e-01 0.003 0 0
Metabolism of polyamines R-HSA-351202 9.937882e-01 0.003 0 0
Peptide hormone metabolism R-HSA-2980736 9.938791e-01 0.003 0 0
PPARA activates gene expression R-HSA-1989781 9.940855e-01 0.003 0 0
ABC transporter disorders R-HSA-5619084 9.941897e-01 0.003 0 0
Cholesterol biosynthesis R-HSA-191273 9.941897e-01 0.003 0 0
Nucleotide salvage R-HSA-8956321 9.943399e-01 0.002 0 0
Collagen degradation R-HSA-1442490 9.943399e-01 0.002 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.943423e-01 0.002 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.943423e-01 0.002 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.947918e-01 0.002 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.949102e-01 0.002 0 0
Phospholipid metabolism R-HSA-1483257 9.949385e-01 0.002 0 0
Mitochondrial protein degradation R-HSA-9837999 9.950553e-01 0.002 0 0
Collagen formation R-HSA-1474290 9.950553e-01 0.002 0 0
Complex I biogenesis R-HSA-6799198 9.953030e-01 0.002 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.955039e-01 0.002 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.957223e-01 0.002 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.958639e-01 0.002 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.958807e-01 0.002 0 0
Antimicrobial peptides R-HSA-6803157 9.962714e-01 0.002 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.962942e-01 0.002 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.964536e-01 0.002 0 0
Nicotinate metabolism R-HSA-196807 9.967717e-01 0.001 0 0
Kidney development R-HSA-9830369 9.967717e-01 0.001 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.970616e-01 0.001 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.973021e-01 0.001 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.973225e-01 0.001 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.973225e-01 0.001 0 0
Keratan sulfate/keratin metabolism R-HSA-1638074 9.975730e-01 0.001 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.975730e-01 0.001 0 0
Neddylation R-HSA-8951664 9.976347e-01 0.001 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.976507e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.977863e-01 0.001 0 0
Metabolism of cofactors R-HSA-8978934 9.977863e-01 0.001 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.978167e-01 0.001 0 0
Complex IV assembly R-HSA-9864848 9.980360e-01 0.001 0 0
Neurotransmitter release cycle R-HSA-112310 9.981118e-01 0.001 0 0
Aspirin ADME R-HSA-9749641 9.981684e-01 0.001 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.982332e-01 0.001 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.985307e-01 0.001 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.985497e-01 0.001 0 0
Paracetamol ADME R-HSA-9753281 9.987139e-01 0.001 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.988431e-01 0.001 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.988620e-01 0.000 0 0
Dectin-2 family R-HSA-5621480 9.989593e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.990686e-01 0.000 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.991579e-01 0.000 0 0
Peroxisomal protein import R-HSA-9033241 9.991579e-01 0.000 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.991579e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.991772e-01 0.000 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.992950e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.993186e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.993923e-01 0.000 0 0
Latent infection - Other responses of Mtb to phagocytosis R-HSA-1222499 9.995539e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.996045e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.996257e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.996391e-01 0.000 0 0
Metabolism of steroid hormones R-HSA-196071 9.996391e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.997374e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.997374e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.997638e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.997638e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.997789e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.997875e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.997906e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.997988e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.998089e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.998454e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.998635e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.998772e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.998882e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.998920e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999125e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.999182e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999656e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999825e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999835e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999864e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999917e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.999936e-01 0.000 0 0
Regulation of Complement cascade R-HSA-977606 9.999936e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999941e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999946e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999953e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.999955e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999956e-01 0.000 1 0
GPCR ligand binding R-HSA-500792 9.999978e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999989e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999991e-01 0.000 0 0
Complement cascade R-HSA-166658 9.999994e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999995e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999995e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999996e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999998e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999998e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999998e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999999e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999999e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 1 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 1 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways