PIM1

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0AVT1 S697 Sugiyama UBA6 MOP4 UBE1L2 HSLEGCFQVIKLLSRRPRNWsQCVELARLKFEKYFNHKALQ
A5A3E0 S1065 Sugiyama POTEF A26C1B ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
O00116 T68 Sugiyama AGPS AAG5 RPREALSTNECKARRAAsAAtAAPtAtPAAQEsGtIPKKRQ
O00165 S153 Sugiyama HAX1 HS1BP1 PDSHQPRIFGGVLESDARSEsPQPAPDWGsQRPFHRFDDVW
O00429 S637 PSP DNM1L DLP1 DRP1 PQKGHAVNLLDVPVPVARKLsAREQRDCEVIERLIKSYFLI
O00571 S594 Sugiyama DDX3X DBX DDX3 MAyEHHyKGssRGRSKssRFsGGFGARDYRQssGAssssFs
O14545 T323 Sugiyama TRAFD1 FLN29 ELLIDHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQNFLQ
O14617 S658 Sugiyama AP3D1 PRO0039 DERPRAVFHEEEQRRPKHRPsEADEEELARRREARKQEQAN
O14618 S267 Sugiyama CCS DGLTIWEERGRPIAGKGRKEsAQPPAHL_____________
O14732 S160 Sugiyama IMPA2 IMP.18P RLYTGRRGRGAFCNGQRLRVsGETDLSKALVLTEIGPKRDP
O14974 S187 Sugiyama PPP1R12A MBS MYPT1 EAARKEEERIMLRDARQWLNsGHINDVRHAKSGGTALHVAA
O14980 S1055 Sugiyama XPO1 CRM1 LEEREIALRQADEEKHKRQMsVPGIFNPHEIPEEMCD____
O15020 S442 Sugiyama SPTBN2 KIAA0302 SCA5 KLEQLAARFDRKAAMRETWLsENQRLVSQDNFGLELAAVEA
O15067 S215 Sugiyama PFAS KIAA0361 LDSWDLDFYTKRFQELQRNPstVEAFDLAQsNsEHSRHWFF
O15143 S336 Sugiyama ARPC1B ARC41 AAGAGLDsLHKNsVsQIsVLsGGKAKCSQFCTTGMDGGMSI
O15234 T13 Sugiyama CASC3 MLN51 ________MADRRRQRAsQDtEDEESGASGsDsGGsPLRGG
O15523 S592 Sugiyama DDX3Y DBY MAyEHHyKGGSRGRSKSNRFsGGFGARDYRQSSGSSSSGFG
O43175 S251 Sugiyama PHGDH PGDH3 VVNCARGGIVDEGALLRALQsGQCAGAALDVFTEEPPRDRA
O43264 S611 Sugiyama ZW10 AQMRAQKGELLERLsSARNFsNMDDEENYSAASKAVRQVLH
O43290 S437 Sugiyama SART1 VVRADDLLPLGDQtQDGDFGsRLRGRGRRRVsEVEEEKEPV
O43390 S426 Sugiyama HNRNPR HNRPR IVLAKPPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPI
O43524 S253 SIGNOR|PSP FOXO3 FKHRL1 FOXO3A WWIINPDGGKsGKAPRRRAVsMDNsNKYTKSRGRAAKKKAA
O43524 T32 SIGNOR|PSP FOXO3 FKHRL1 FOXO3A sPLEVELDPEFEPQSRPRsCtWPLQRPELQAsPAKPSGETA
O60271 S183 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 HTEMIHNYMEHLERTKLHQLsGsDQLEstAHsRIRKERPIs
O60271 S194 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 LERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPAGDG
O60271 T191 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 MEHLERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPA
O60293 S42 Sugiyama ZFC3H1 CCDC131 KIAA0546 PSRC2 LEDGEIsDDDNNSQIRSRsssSsSGGGLLPYPRRRPPHSAR
O60343 S485 Sugiyama TBC1D4 AS160 KIAA0603 CERIEGLYPPRAKLVIQRHLssLtDNEQADIFERVQKMKPV
O60343 S751 Sugiyama TBC1D4 AS160 KIAA0603 EIRQDTASESSDGEGRKRtSstCsNEsLsVGGTSVTPRRIS
O60343 T749 Sugiyama TBC1D4 AS160 KIAA0603 ENEIRQDTASESSDGEGRKRtSstCsNEsLsVGGTSVTPRR
O60381 S372 SIGNOR|PSP HBP1 DTFKSYDFTPMDSSAVYVLSsMARQRRAsLsCGGPGGQDFA
O60381 S380 SIGNOR|PSP HBP1 TPMDSSAVYVLSsMARQRRAsLsCGGPGGQDFARSGFSKNC
O60664 S175 Sugiyama PLIN3 M6PRBP1 TIP47 RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK
O60664 S93 Sugiyama PLIN3 M6PRBP1 TIP47 AAVsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQP
O60739 T45 Sugiyama EIF1B AGTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKK
O60814 S37 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
O60814 Y38 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
O60841 S182 Sugiyama EIF5B IF2 KIAA0741 DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK
O75140 S1530 PSP DEPDC5 KIAA0645 FLQLPYSKRKFSGQQRRRRNstsstNQNMFCEERVGYNWAY
O75534 T761 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR GPKAVAAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDN
O75937 S81 Sugiyama DNAJC8 SPF31 HSPC315 HSPC331 VLQIDPEVTDEEIKKRFRQLsILVHPDKNQDDADRAQKAFE
O76003 S117 Sugiyama GLRX3 PICOT TXNL2 HUSSY-22 IDRLDGAHAPELTKKVQRHAssGsFLPSANEHLKEDLNLRL
O95155 S23 Sugiyama UBE4B HDNB1 KIAA0684 UFD2 ELSADEIRRRRLARLAGGQtsQPttPLtsPQRENPPGPPIA
O95263 S401 Sugiyama PDE8B PIG22 CCTTDNNKQIHKIHRDSGDNsQTEPHSFRYKNRRKESIDVK
O95639 S267 Sugiyama CPSF4 CPSF30 NAR NEB1 KCGEKGHYANRCTKGHLAFLsGQ__________________
O95644 S151 SIGNOR|PSP NFATC1 NFAT2 NFATC NNNQFFHDVEVEDVLPSSKRsPstATLSLPsLEAYRDPsCL
O95644 S153 SIGNOR|PSP NFATC1 NFAT2 NFATC NQFFHDVEVEDVLPSSKRsPstATLSLPsLEAYRDPsCLsP
O95644 S245 SIGNOR|PSP NFATC1 NFAT2 NFATC LGACtLLGsPRHsPstsPRAsVTEESWLGARssRPAsPCNK
O95644 S256 SIGNOR|PSP NFATC1 NFAT2 NFATC HsPstsPRAsVTEESWLGARssRPAsPCNKRKYsLNGRQPP
O95644 S257 SIGNOR|PSP NFATC1 NFAT2 NFATC sPstsPRAsVTEESWLGARssRPAsPCNKRKYsLNGRQPPy
O95644 S269 SIGNOR|PSP NFATC1 NFAT2 NFATC ESWLGARssRPAsPCNKRKYsLNGRQPPysPHHsPtPSPHG
O95644 S278 PSP NFATC1 NFAT2 NFATC RPAsPCNKRKYsLNGRQPPysPHHsPtPSPHGsPRVsVTDD
O95644 S335 SIGNOR|PSP NFATC1 NFAT2 NFATC AINALTTDSsLDLGDGVPVKsRKttLEQPPsVALKVEPVGE
O95644 T154 SIGNOR|PSP NFATC1 NFAT2 NFATC QFFHDVEVEDVLPSSKRsPstATLSLPsLEAYRDPsCLsPA
O95644 T338 SIGNOR|PSP NFATC1 NFAT2 NFATC ALTTDSsLDLGDGVPVKsRKttLEQPPsVALKVEPVGEDLG
O95644 T339 SIGNOR|PSP NFATC1 NFAT2 NFATC LTTDSsLDLGDGVPVKsRKttLEQPPsVALKVEPVGEDLGs
O95757 S587 Sugiyama HSPA4L APG1 HSPH3 OSP94 RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM
O95831 S100 Sugiyama AIFM1 AIF PDCD8 AGAYAYKTMKEDEKRyNERIsGLGLtPEQKQKKAALsAsEG
O95831 S116 Sugiyama AIFM1 AIF PDCD8 NERIsGLGLtPEQKQKKAALsAsEGEEVPQDKAPSHVPFLL
P00338 S161 PSP|Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S319 PSP LDHA PIG19 GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______
P00491 S163 Sugiyama PNP NP GQNPLRGPNDERFGDRFPAMsDAyDRtMRQRALstWKQMGE
P00491 S176 Sugiyama PNP NP GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P01106 S308 PSP MYC BHLHE39 PGKRSESGSPSAGGHSKPPHsPLVLKRCHVSTHQHNYAAPP
P02545 S12 Sugiyama LMNA LMN1 _________METPsQRRAtRsGAQAsstPLsPtRItRLQEK
P02545 S437 Sugiyama LMNA LMN1 KKRKLEstEsRssFsQHARtsGRVAVEEVDEEGKFVRLRNK
P02545 S458 Sugiyama LMNA LMN1 GRVAVEEVDEEGKFVRLRNKsNEDQsMGNWQIKRQNGDDPL
P02545 T10 Sugiyama LMNA LMN1 ___________METPsQRRAtRsGAQAsstPLsPtRItRLQ
P02545 T436 Sugiyama LMNA LMN1 tKKRKLEstEsRssFsQHARtsGRVAVEEVDEEGKFVRLRN
P04040 T29 Sugiyama CAT SDQMQHWKEQRAAQKADVLttGAGNPVGDKLNVItVGPRGP
P04040 T434 Sugiyama CAT QQPSALEHSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEE
P04075 S346 Sugiyama ALDOA ALDA EEYVKRALANsLACQGKytPsGQAGAAAsEsLFVsNHAy__
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T65 Sugiyama ALDOA ALDA QsIGtENtEENRRFyRQLLLtADDRVNPCIGGVILFHETLY
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792 S83 Sugiyama HSPB1 HSP27 HSP28 IEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNH
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P06733 S27 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06899 S37 Sugiyama H2BC11 H2BFR HIST1H2BJ KAVTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISS
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07437 T55 Sugiyama TUBB TUBB5 OK/SW-cl.56 tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs
P07737 S133 Sugiyama PFN1 LMGKEGVHGGLINKKCyEMAsHLRRsQY_____________
P07814 S1336 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 SEEDKEALIAKCNDYRRRLLsVNIRVRADLRDNysPGWKFN
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S470 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA HEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKH
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900 T467 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN
P07900 Y466 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KLGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKE
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S460 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S474 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQV
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 T459 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEt
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08670 S55 Sugiyama VIM TRtYsLGsALRPstsRsLyAssPGGVyAtRssAVRLRssVP
P08670 T63 Sugiyama VIM ALRPstsRsLyAssPGGVyAtRssAVRLRssVPGVRLLQDs
P08670 Y61 Sugiyama VIM GsALRPstsRsLyAssPGGVyAtRssAVRLRssVPGVRLLQ
P08708 Y84 Sugiyama RPS17 RPS17L GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE
P08865 S75 Sugiyama RPSA LAMBR LAMR1 WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG
P08865 T82 Sugiyama RPSA LAMBR LAMR1 ARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPIAGR
P08865 T94 Sugiyama RPSA LAMBR LAMR1 VsVIssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQA
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09110 S206 Sugiyama ACAA1 ACAA PTHIO ENVAERFGISREKQDTFALAsQQKAARAQSKGCFQAEIVPV
P09874 S274 Sugiyama PARP1 ADPRT PPOL KVCstNDLKELLIFNKQQVPsGEsAILDRVADGMVFGALLP
P0CG38 S1065 Sugiyama POTEI ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1028 Sugiyama POTEJ ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG47 S57 Sugiyama UBB PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0CG48 S57 Sugiyama UBC PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0DPH7 S54 Sugiyama TUBA3C TUBA2 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P10275 S215 PSP AR DHTR NR3C4 QQQQQEAVSEGssSGRAREAsGAPTsSKDNyLGGTSTISDN
P10275 S220 PSP AR DHTR NR3C4 EAVSEGssSGRAREAsGAPTsSKDNyLGGTSTISDNAKELC
P10275 T851 PSP AR DHTR NR3C4 LRMNYIKELDRIIACKRKNPtSCSRRFYQLTKLLDSVQPIA
P10412 S36 Sugiyama H1-4 H1F4 HIST1H1E EKtPVKKKARKsAGAAKRKAsGPPVsELItKAVAASKERsG
P10619 S51 Sugiyama CTSA PPGB DQDEIQRLPGLAKQPSFRQYsGYLKGSGSKHLHYWFVESQK
P10809 T422 Sugiyama HSPD1 HSP60 AVLKVGGtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGC
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11277 S439 Sugiyama SPTB SPTB1 KLEQLARRFDRKAAMRETWLsENQRLVAQDNFGYDLAAVEA
P11309 S189 Sugiyama PIM1 KDENILIDLNRGELKLIDFGsGALLKDTVYTDFDGTRVYSP
P11586 S129 Sugiyama MTHFD1 MTHFC MTHFD INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP
P11586 S318 Sugiyama MTHFD1 MTHFC MTHFD FKPGKWMIQYNNLNLKTPVPsDIDIsRSCKPKPIGKLAREI
P11940 T191 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 GRFKSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLF
P11940 T379 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 AtKPLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINP
P12004 S172 Sugiyama PCNA sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE
P12268 S425 Sugiyama IMPDH2 IMPD2 GIRLKKyRGMGsLDAMDKHLssQNRyFsEADKIKVAQGVsG
P12268 S432 Sugiyama IMPDH2 IMPD2 RGMGsLDAMDKHLssQNRyFsEADKIKVAQGVsGAVQDKGS
P12268 Y430 Sugiyama IMPDH2 IMPD2 KyRGMGsLDAMDKHLssQNRyFsEADKIKVAQGVsGAVQDK
P12277 S129 Sugiyama CKB CKBB DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG
P12277 T322 Sugiyama CKB CKBB LGKHEKFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRL
P12277 T327 Sugiyama CKB CKBB KFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRLGFSEV
P13489 S178 Sugiyama RNH1 PRI RNH SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S584 Sugiyama EEF2 EF2 DHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyM
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13674 S387 Sugiyama P4HA1 P4HA NPITGDLETVHYRISKsAWLsGyENPVVsRINMRIQDLTGL
P13674 Y282 Sugiyama P4HA1 P4HA ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP
P13798 S27 Sugiyama APEH D3F15S2 D3S48E DNF15S2 LsEPEEAAALyRGLSRQPALsAACLGPEVtTQyGGQyRTVH
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P14314 S108 Sugiyama PRKCSH G19P1 PSNRVNDGVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQ
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T95 Sugiyama PKM OIP3 PK2 PK3 PKM2 NFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTK
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S514 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK
P14625 S64 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14625 S680 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 RIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDMLRR
P14625 T519 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 DHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIy
P14866 S544 Sugiyama HNRNPL HNRPL P/OKcl.14 LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH
P15259 T96 Sugiyama PGAM2 PGAMM QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQVKIWR
P15311 S144 Sugiyama EZR VIL2 LLGSYAVQAKFGDYNKEVHKsGyLSsERLIPQRVMDQHKLT
P15311 S535 Sugiyama EZR VIL2 EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P16402 S37 Sugiyama H1-3 H1F3 HIST1H1D KtPVKKKAKKAGATAGKRKAsGPPVsELItKAVAASKERsG
P16403 S36 Sugiyama H1-2 H1F2 HIST1H1C EKAPVKKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsG
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17655 S462 Sugiyama CAPN2 CANPL2 GQTNIHLSKNFFLTNRARERsDtFINLREVLNRFKLPPGEY
P17812 S575 Sugiyama CTPS1 CTPS LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18124 T170 Sugiyama RPL7 VNELIyKRGYGKINKKRIALtDNALIARSLGKyGIICMEDL
P18206 S820 Sugiyama VCL DAKAVAGNIsDPGLQKsFLDsGyRILGAVAKVREAFQPQEP
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18669 T146 Sugiyama PGAM1 PGAMA CDABP0006 MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF
P18669 T96 Sugiyama PGAM1 PGAMA CDABP0006 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P21108 S8 Sugiyama PRPS1L1 PRPS3 PRPSL _____________MPNIKIFsGssHQDLSQKIADRLGLELG
P21333 S1084 Sugiyama FLNA FLN FLN1 PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV
P21333 S1301 Sugiyama FLNA FLN FLN1 DARALtQtGGPHVKARVANPsGNLTEtyVQDRGDGMYKVEy
P22033 S481 Sugiyama MMUT MUT EGIPKLRIEECAARRQARIDsGSEVIVGVNKYQLEKEDAVE
P22059 S382 Sugiyama OSBP OSBP1 APEIITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLEETK
P22314 S1020 Sugiyama UBA1 A1S9T UBE1 FFMPAAKLKERLDQPMtEIVsRVSKRKLGRHVRALVLELCC
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P22626 S344 Sugiyama HNRNPA2B1 HNRPA2B1 sRNMGGPyGGGNyGPGGsGGsGGyGGRsRy___________
P22626 Y347 Sugiyama HNRNPA2B1 HNRPA2B1 MGGPyGGGNyGPGGsGGsGGyGGRsRy______________
P23396 T70 Sugiyama RPS3 OK/SW-cl.26 ILATRTQNVLGEKGRRIRELtAVVQKRFGFPEGsVELyAEK
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23527 S37 Sugiyama H2BC17 H2BFH H2BFN HIST1H2BO KAVTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISS
P23588 S406 Sugiyama EIF4B KLQRQLDEPKLERRPRERHPsWRsEEtQERERsRtGsEssQ
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P25786 Y6 Sugiyama PSMA1 HC2 NU PROS30 PSC2 _______________MFRNQyDNDVtVWsPQGRIHQIEYAM
P25789 S7 Sugiyama PSMA4 HC9 PSC9 ______________MSRRyDsRttIFsPEGRLYQVEYAMEA
P26038 S144 Sugiyama MSN LLASyAVQSKYGDFNKEVHKsGYLAGDKLLPQRVLEQHKLN
P26373 S106 Sugiyama RPL13 BBC1 OK/SW-cl.46 IHKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLIL
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 S97 Sugiyama RPL13 BBC1 OK/SW-cl.46 sLEELRVAGIHKKVARTIGIsVDPRRRNKstEsLQANVQRL
P26373 T107 Sugiyama RPL13 BBC1 OK/SW-cl.46 HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF
P26639 S39 Sugiyama TARS1 TARS PIGAGEEKQKEGGKKKNKEGsGDGGRAELNPWPEyIytRLE
P26639 S702 Sugiyama TARS1 TARS ISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEE
P26641 S25 Sugiyama EEF1G EF1G PRO1608 TLyTyPENWRAFKALIAAQYsGAQVRVLsAPPHFHFGQtNR
P26885 S108 Sugiyama FKBP2 FKBP13 GWDQGLLGMCEGEKRKLVIPsELGyGERGAPPKIPGGATLV
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27448 S45 Sugiyama MARK3 CTAK1 EMK2 RQEVTSRTSRSGARCRNsIAsCADEQPHIGNyRLLKTIGKG
P27448 S96 SIGNOR|PSP MARK3 CTAK1 EMK2 ILTGREVAIKIIDKtQLNPtsLQKLFREVRIMKILNHPNIV
P27448 T90 SIGNOR|PSP MARK3 CTAK1 EMK2 VKLARHILTGREVAIKIIDKtQLNPtsLQKLFREVRIMKIL
P27448 T95 SIGNOR|PSP MARK3 CTAK1 EMK2 HILTGREVAIKIIDKtQLNPtsLQKLFREVRIMKILNHPNI
P27708 S1859 Sugiyama CAD RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27824 S362 Sugiyama CANX WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK
P27824 T66 Sugiyama CANX KPDTTAPPSSPKVTYKAPVPtGEVyFADsFDRGTLSGWILS
P29401 S104 Sugiyama TKT AVWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGs
P29401 S332 Sugiyama TKT GDKIATRKAYGQALAKLGHAsDRIIALDGDtKNstFsEIFK
P29474 S633 PSP NOS3 FNsISCSDPLVssWRRKRKEssNtDSAGALGTLRFCVFGLG
P29692 S74 Sugiyama EEF1D EF1D RENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVENQsL
P30041 T49 Sugiyama PRDX6 AOP2 KIAA0106 LGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKLI
P30043 S198 Sugiyama BLVRB FLR SCAN KHDLGHFMLRCLttDEyDGHstyPsHQyQ____________
P30050 S26 Sugiyama RPL12 DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI
P30050 T18 Sugiyama RPL12 ___MPPKFDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLs
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30304 S116 GPS6|ELM CDC25A ENLENPMRRIHsLPQKLLGCsPALKRSHsDSLDHDIFQLID
P30533 S242 Sugiyama LRPAP1 A2MRAP TELKEKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWD
P30876 S882 Sugiyama POLR2B GDDVIIGKTVtLPENEDELEstNRRYTKRDCSTFLRTSETG
P31327 S819 Sugiyama CPS1 MAIGRTFEEsFQKALRMCHPsIEGFTPRLPMNKEWPsNLDL
P31939 S554 Sugiyama ATIC PURH OK/SW-cl.86 VSISSDAFFPFRDNVDRAKRsGVAyIAAPSGsAADKVVIEA
P31943 S269 Sugiyama HNRNPH1 HNRPH HNRPH1 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH
P31943 S54 Sugiyama HNRNPH1 HNRPH HNRPH1 CKIQNGAQGIRFIYTREGRPsGEAFVELEsEDEVKLALKKD
P31946 S132 Sugiyama YWHAB TQPESKVFyLKMKGDYFRyLsEVAsGDNKQTtVsNsQQAyQ
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P32119 S112 Sugiyama PRDX2 NKEFB TDPX1 KEGGLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFII
P32119 T142 Sugiyama PRDX2 NKEFB TDPX1 EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF
P33316 S120 Sugiyama DUT PsKRARPAEVGGMQLRFARLsEHAtAPTRGsARAAGYDLYS
P33316 S164 Sugiyama DUT YTIPPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDV
P33527 S915 Sugiyama ABCC1 MRP MRP1 QMENGMLVTDsAGKQLQRQLsssssysGDISRHHNstAELQ
P33778 S37 Sugiyama H2BC3 H2BFF HIST1H2BB KAITKAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISS
P33992 T404 Sugiyama MCM5 CDC46 GTAKSQLLKFVEKCsPIGVytsGKGSSAAGLtAsVMRDPss
P33993 S678 Sugiyama MCM7 CDC47 MCM2 ADVIFATVRELVSGGRSVRFsEAEQRCVSRGFTPAQFQAAL
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34932 S76 Sugiyama HSPA4 APG2 HSPH2 VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT
P35269 T156 Sugiyama GTF2F1 RAP74 EAFPVHNWYNFTPLARHRtLtAEEAEEEWERRNKVLNHFSI
P35568 S1101 PSP IRS1 RNQSAKVIRADPQGCRRRHssEtFsstPSATRVGNTVPFGA
P35613 S277 Sugiyama BSG UNQ6505/PRO21383 KITDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPG
P35613 S279 Sugiyama BSG UNQ6505/PRO21383 TDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQy
P35658 S974 Sugiyama NUP214 CAIN CAN KIAA0023 RKTPPVRSTAPASLSRSAFLsQRYYEDLDEVSSTSSVSQSL
P36578 S55 Sugiyama RPL4 RPL1 DIVNFVHTNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVAR
P36578 S63 Sugiyama RPL4 RPL1 NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG
P36578 S66 Sugiyama RPL4 RPL1 KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P36871 S483 Sugiyama PGM1 DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR
P36888 Y591 SIGNOR FLT3 CD135 FLK2 STK1 RyESQLQMVQVTGSSDNEyFyVDFREyEyDLKWEFPRENLE
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37837 S13 Sugiyama TALDO1 TAL TALDO TALDOR ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA
P38646 S212 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38936 S146 SIGNOR|ELM|PSP CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 QAEGsPGGPGDSQGRKRRQtsMTDFYHsKRRLIFSKRKP__
P38936 T145 SIGNOR|ELM|iPTMNet|PSP CDKN1A CAP20 CDKN1 CIP1 MDA6 PIC1 SDI1 WAF1 EQAEGsPGGPGDSQGRKRRQtsMTDFYHsKRRLIFSKRKP_
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40227 S49 Sugiyama CCT6A CCT6 CCTZ GLQDVLRTNLGPKGTMKMLVsGAGDIKLTKDGNVLLHEMQI
P40818 S719 Sugiyama USP8 KIAA0055 UBPY KPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtPT
P40925 S153 Sugiyama MDH1 MDHA ANtNCLtAsKSAPSIPKENFsCLtRLDHNRAKAQIALKLGV
P40939 T418 Sugiyama HADHA HADH DRGQQQVFKGLNDKVKKKALtSFERDSIFSNLTGQLDyQGF
P41567 T45 Sugiyama EIF1 SUI1 AGTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKK
P42166 S158 Sugiyama TMPO LAP2 tRKLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsN
P42166 S159 Sugiyama TMPO LAP2 RKLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsND
P42166 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs
P42167 S158 Sugiyama TMPO LAP2 TRKLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSN
P42167 S159 Sugiyama TMPO LAP2 RKLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSND
P42167 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P46013 S299 Sugiyama MKI67 GLQGETQLLVSRKSRPKsGGsGHAVAEPAsPEQELDQNKGK
P46527 T157 SIGNOR|PSP CDKN1B KIP1 p27 PsDsQTGLAEQCAGIRKRPAtDDSSTQNKRANRTEENVsDG
P46527 T198 SIGNOR|PSP CDKN1B KIP1 p27 sPNAGSVEQtPKKPGLRRRQt____________________
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46776 T95 Sugiyama RPL27A LDKLWtLVsEQtRVNAAKNKtGAAPIIDVVRsGyyKVLGKG
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46779 S115 Sugiyama RPL28 HMIRKNKYRPDLRMAAIRRAsAILRSQKPVMVKRKRTRPTK
P47756 S184 Sugiyama CAPZB TAHYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVs
P47756 S192 PSP CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P47756 S226 PSP CAPZB CsPHIANIGRLVEDMENKIRstLNEIyFGKTKDIVNGLRSV
P47756 T186 PSP CAPZB HYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDC
P47756 T194 Sugiyama CAPZB MLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIANIG
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P49321 S662 Sugiyama NASP LKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsstsGF
P49327 S1997 Sugiyama FASN FAS DGLLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFV
P49327 S265 Sugiyama FASN FAS TILNAGTNTDGFKEQGVtFPsGDIQEQLIRSLyQsAGVAPE
P49368 T430 Sugiyama CCT3 CCTG TRIC5 GGGASEMAVAHALTEKSKAMtGVEQWPyRAVAQALEVIPRT
P49411 T276 Sugiyama TUFM DLEKPFLLPVEAVYSVPGRGtVVTGTLERGILKKGDECELL
P49419 S84 Sugiyama ALDH7A1 ATQ1 EVIttyCPANNEPIARVRQAsVADyEEtVKKAREAWKIWAD
P50990 S162 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 ILPNLVCCsAKNLRDIDEVssLLRTSIMSKQyGNEVFLAKL
P50990 S23 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 LHVPKAPGFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTT
P51116 S504 Sugiyama FXR2 FMR1L2 PTGGRGRGPPPAPRPTSRYNsSsISSVLKDPDsNPYSLLDt
P51116 S603 Sugiyama FXR2 FMR1L2 QRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQsR
P51116 Y614 Sugiyama FXR2 FMR1L2 RGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPs
P51692 S731 PSP STAT5B FVNASADAGGGSATyMDQAPsPAVCPQAHyNMyPQNPDSVL
P51991 S358 Sugiyama HNRNPA3 HNRPA3 QQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF
P52209 S129 Sugiyama PGD PGDH TTRRCRDLKAKGILFVGsGVsGGEEGARyGPSLMPGGNKEA
P52597 S54 Sugiyama HNRNPF HNRPF CtIHDGAAGVHFIYTREGRQsGEAFVELGsEDDVKMALKKD
P52907 S106 PSP CAPZA1 RFLDPRNKISFKFDHLRKEAsDPQPEEADGGLKsWREsCDs
P52907 S126 PSP CAPZA1 sDPQPEEADGGLKsWREsCDsALRAYVKDHYSNGFCTVYAK
P53365 S260 Sugiyama ARFIP2 POR1 TDLEELsLGPRDAGTRGRLEsAQATFQAHRDKYEKLRGDVA
P53396 S455 Sugiyama ACLY ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP
P53999 S56 Sugiyama SUB1 PC4 RPO2TC1 PVKKQKTGETsRALsssKQssssRDDNMFQIGKMRYVSVRD
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P55072 S718 Sugiyama VCP HEL-220 HEL-S-70 AIREsIEsEIRRERERQtNPsAMEVEEDDPVPEIRRDHFEE
P55735 S184 Sugiyama SEC13 D3S1231E SEC13A SEC13L1 SEC13R PGsLIDHPSGQKPNYIKRFAsGGCDNLIKLWKEEEDGQWKE
P55795 S269 Sugiyama HNRNPH2 FTP3 HNRPH2 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH
P57053 S37 Sugiyama H2BC12L H2BFS H2BS1 KAVTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIss
P57053 Y38 Sugiyama H2BC12L H2BFS H2BS1 AVTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssK
P57721 S59 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT EGGLNVTLTIRLLMHGKEVGsIIGKKGETVKKMREESGARI
P57721 S82 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK
P57721 T159 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT sQCGsLIGKGGSKIKEIREstGAQVQVAGDMLPNstERAVT
P57723 S31 Sugiyama PCBP4 EPELSITLTLRMLMHGKEVGsIIGKKGETVKRIREQSSARI
P58876 S37 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
P58876 Y38 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S300 Sugiyama ACTB NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P60709 S365 Sugiyama ACTB ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60842 T80 Sugiyama EIF4A1 DDX2A EIF4A QRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDLKA
P60891 S8 Sugiyama PRPS1 _____________MPNIKIFsGssHQDLSQKIADRLGLELG
P61073 S339 PSP CXCR4 sVsRGssLKILsKGKRGGHssVstEsEsssFHss_______
P61221 Y594 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 RPRINKLNsIKDVEQKKsGNyFFLDD_______________
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 S12 Sugiyama RPL26 _________MKFNPFVtsDRsKNRKRHFNAPsHIRRKIMss
P61313 S100 Sugiyama RPL15 EC45 TCBAP0781 tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW
P61769 T106 Sugiyama B2M CDABP0092 HDCMA22P YYTEFTPTEKDEYACRVNHVtLsQPKIVKWDRDM_______
P61978 S417 Sugiyama HNRNPK HNRPK DLAGsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITI
P61978 S420 Sugiyama HNRNPK HNRPK GsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITItGt
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981 T31 Sugiyama YWHAG ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN
P62241 S115 Sugiyama RPS8 OK/SW-cl.83 TLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEE
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S114 Sugiyama RPS14 PRO2640 HIKLRATGGNRtKtPGPGAQsALRALARSGMKIGRIEDVtP
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 S74 Sugiyama RPS11 tyIDKKCPFTGNVsIRGRILsGVVTKMKMQRTIVIRRDYLH
P62280 T15 Sugiyama RPS11 ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62701 T247 Sugiyama RPS4X CCG2 RPS4 SCAR VIGKGNKPWIsLPRGKGIRLtIAEERDKRLAAKQSSG____
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62753 S148 Sugiyama RPS6 OK/SW-cl.2 tVPRRLGPKRASRIRKLFNLsKEDDVRQyVVRKPLNKEGKK
P62753 S53 Sugiyama RPS6 OK/SW-cl.2 AtEVAADALGEEWKGYVVRIsGGNDKQGFPMKQGVLTHGRV
P62805 S48 Sugiyama H4C1 H4/A H4FA HIST1H4A; H4C2 H4/I H4FI HIST1H4B; H4C3 H4/G H4FG HIST1H4C; H4C4 H4/B H4FB HIST1H4D; H4C5 H4/J H4FJ HIST1H4E; H4C6 H4/C H4FC HIST1H4F; H4C8 H4/H H4FH HIST1H4H; H4C9 H4/M H4FM HIST1H4I; H4C11 H4/E H4FE HIST1H4J; H4C12 H4/D H4FD HIST1H4K; H4C13 H4/K H4FK HIST1H4L; H4C14 H4/N H4F2 H4FN HIST2H4 HIST2H4A; H4C15 H4/O H4FO HIST2H4B; H4C16 H4-16 HIST4H4 QGItKPAIRRLARRGGVKRIsGLIyEETRGVLKVFLENVIR
P62807 S37 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI KAVTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIss
P62807 Y38 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI AVTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssK
P62826 T32 Sugiyama RAN ARA24 OK/SW-cl.81 KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62826 Y146 Sugiyama RAN ARA24 OK/SW-cl.81 IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR
P62826 Y147 Sugiyama RAN ARA24 OK/SW-cl.81 KDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARK
P62888 S75 Sugiyama RPL30 LRKsEIEyyAMLAKtGVHHysGNNIELGtACGKyyRVCtLA
P62888 Y74 Sugiyama RPL30 ALRKsEIEyyAMLAKtGVHHysGNNIELGtACGKyyRVCtL
P62910 S105 Sugiyama RPL32 PP9932 LEVLLMCNKsyCAEIAHNVSsKNRKAIVERAAQLAIRVTNP
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62979 S123 Sugiyama RPS27A UBA80 UBCEP1 LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK
P62979 S57 Sugiyama RPS27A UBA80 UBCEP1 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA
P62987 S57 Sugiyama UBA52 UBCEP2 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63104 S63 Sugiyama YWHAZ LLsVAyKNVVGARRssWRVVssIEQKTEGAEKKQQMAREYR
P63104 S64 SIGNOR|PSP YWHAZ LsVAyKNVVGARRssWRVVssIEQKTEGAEKKQQMAREYRE
P63104 T30 Sugiyama YWHAZ AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S300 Sugiyama ACTG1 ACTG NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P63261 S365 Sugiyama ACTG1 ACTG ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P67809 S209 Sugiyama YBX1 NSEP1 YB1 RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809 T126 Sugiyama YBX1 NSEP1 YB1 GEtVEFDVVEGEKGAEAANVtGPGGVPVQGsKYAADRNHYR
P67809 Y196 Sugiyama YBX1 NSEP1 YB1 sAPEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGE
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 S54 Sugiyama TUBA1B GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P68400 T13 Sugiyama CSNK2A1 CK2A1 ________MSGPVPSRARVytDVNTHRPREYWDYESHVVEW
P68431 S11 SIGNOR H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J __________MARtKQtARKstGGKAPRKQLATKAARKsAP
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P78345 S253 Sugiyama RPP38 DtsFEDLsKPKRKLADGRQAsVtLQPLKIKKLIPNPNKIRK
P78371 S144 Sugiyama CCT2 99D8.1 CCTB QTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIAG
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q00534 T49 Sugiyama CDK6 CDKN6 KARDLKNGGRFVALKRVRVQtGEEGMPLsTIREVAVLRHLE
Q00610 S147 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 VYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLLL
Q00839 S585 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRKAVV
Q00839 Y260 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED
Q00987 S166 SIGNOR|PSP MDM2 KPSSSHLVSRPstSSRRRAIsEtEENsDELsGERQRKRHKs
Q00987 S186 SIGNOR|PSP MDM2 sEtEENsDELsGERQRKRHKsDsISLsFDESLALCVIREIC
Q01082 S439 Sugiyama SPTBN1 SPTB2 KLEQLARRFDRKAAMRETWLsENQRLVsQDNFGFDLPAVEA
Q01105 S161 Sugiyama SET FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01844 S274 Sugiyama EWSR1 EWS YSQQSSSYGQQSsFRQDHPssMGVyGQESGGFSGPGENRSM
Q01860 S288 PSP POU5F1 OCT3 OCT4 OTF3 GLEKDVVRVWFCNRRQKGKRssSDYAQREDFEAAGSPFSGG
Q01860 S289 PSP POU5F1 OCT3 OCT4 OTF3 LEKDVVRVWFCNRRQKGKRssSDYAQREDFEAAGSPFSGGP
Q02543 S123 Sugiyama RPL18A AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK
Q02543 T102 Sugiyama RPL18A LRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAH
Q02543 Y97 Sugiyama RPL18A NFGIWLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARH
Q02878 T213 Sugiyama RPL6 TXREB1 FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q04206 S276 SIGNOR|PSP RELA NFKB3 PYADPsLQAPVRVsMQLRRPsDRELsEPMEFQYLPDTDDRH
Q04446 S53 Sugiyama GBE1 EIDPYLKPYAVDFQRRYKQFsQILKNIGENEGGIDKFSRGy
Q04446 T570 Sugiyama GBE1 DFPRKGNNESYHYARRQFHLtDDDLLRYKFLNNFDRDMNRL
Q04695 S32 Sugiyama KRT17 SsIKGSSGLGGGsSRTsCRLsGGLGAGsCRLGSAGGLGSTL
Q04726 S197 Sugiyama TLE3 KIAA1547 HLTVKDEKNHHELDHREREssANNsVsPsEsLRAsEKHRGs
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06830 T143 Sugiyama PRDX1 PAGA PAGB TDPX2 EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF
Q06830 Y116 Sugiyama PRDX1 PAGA PAGB TDPX2 GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK
Q07020 S140 Sugiyama RPL18 ILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAPGtPH
Q07021 S106 Sugiyama C1QBP GC1QBP HABP1 SF2P32 LsDEIKEERKIQKHKTLPKMsGGWELELNGTEAKLVRKVAG
Q08945 S657 Sugiyama SSRP1 FACT80 MEKKSTPSRGsSSKSsSRQLsEsFKSKEFVssDEsssGENK
Q08J23 S593 Sugiyama NSUN2 SAKI TRM4 NNSEKMKVINTGIKVWCRNNsGEEFDCAFRLAQEGIYTLYP
Q09161 S22 Sugiyama NCBP1 CBP80 NCBP SRRRHsDENDGGQPHKRRKtsDANEtEDHLEsLICKVGEKS
Q12792 T345 Sugiyama TWF1 PTK9 KPKGPAGKRGIRRLIRGPAEtEAttD_______________
Q13033 S229 Sugiyama STRN3 GS2NA SG2NA SEPNGsVETKNLEQILNGGEsPKQKGQEIKRSSGDVLETFN
Q13200 S361 SIGNOR|PSP PSMD2 TRAP2 EPKVPDDIyKtHLENNRFGGsGsQVDSARMNLASSFVNGFV
Q13263 S473 Sugiyama TRIM28 KAP1 RNF96 TIF1B sGDDPyssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERL
Q13283 S232 Sugiyama G3BP1 G3BP EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA
Q13309 S64 SIGNOR|PSP SKP2 FBXL1 EEPDsENIPQELLsNLGHPEsPPRKRLKsKGsDKDFVIVRR
Q13309 S72 SIGNOR|PSP SKP2 FBXL1 PQELLsNLGHPEsPPRKRLKsKGsDKDFVIVRRPKLNRENF
Q13309 T417 SIGNOR|PSP SKP2 FBXL1 ARPTIGNKKNQEIWGIKCRLtLQKPSCL_____________
Q13310 S96 Sugiyama PABPC4 APP1 PABP4 VIKGKPIRIMWSQRDPsLRKsGVGNVFIKNLDKSIDNKALy
Q13310 T191 Sugiyama PABPC4 APP1 PABP4 GRFKSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELF
Q13310 T379 Sugiyama PABPC4 APP1 PABP4 GsKPLyVALAQRKEERKAHLtNQyMQRVAGMRALPANAILN
Q13442 S19 Sugiyama PDAP1 HASPP28 __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE
Q13442 T18 Sugiyama PDAP1 HASPP28 ___MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEE
Q13561 S83 Sugiyama DCTN2 DCTN50 GTKGLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKY
Q13561 Y86 Sugiyama DCTN2 DCTN50 GLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKYQRL
Q13761 S149 PSP RUNX3 AML2 CBFA3 PEBP2A3 KNQVARFNDLRFVGRSGRGKsFtLtItVFTNPTQVATYHRA
Q13761 T151 PSP RUNX3 AML2 CBFA3 PEBP2A3 QVARFNDLRFVGRSGRGKsFtLtItVFTNPTQVATYHRAIK
Q13761 T153 PSP RUNX3 AML2 CBFA3 PEBP2A3 ARFNDLRFVGRSGRGKsFtLtItVFTNPTQVATYHRAIKVt
Q13761 T155 PSP RUNX3 AML2 CBFA3 PEBP2A3 FNDLRFVGRSGRGKsFtLtItVFTNPTQVATYHRAIKVtVD
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14152 T1372 Sugiyama EIF3A EIF3S10 KIAA0139 EKASWRAEKDREsLRRTKNEtDEDGWttVRR__________
Q14203 T524 Sugiyama DCTN1 EAAQEtVADyQQTIKKYRQLtAHLQDVNRELTNQQEAsVER
Q14240 T81 Sugiyama EIF4A2 DDX2B EIF4F QRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEFKE
Q14566 S271 Sugiyama MCM6 VPDVSKLSTPGARAEtNsRVsGVDGyEtEGIRGLRALGVRD
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14671 T112 Sugiyama PUM1 KIAA0099 PUMH1 QLGGGGsGGGGyNNsKHRWPtGDNIHAEHQVRsMDELNHDF
Q14697 S187 Sugiyama GANAB G2AN KIAA0088 LLsVNARGLLEFEHQRAPRVsQGsKDPAEGDGAQPEEtPRD
Q14697 S190 Sugiyama GANAB G2AN KIAA0088 VNARGLLEFEHQRAPRVsQGsKDPAEGDGAQPEEtPRDGDK
Q15056 S13 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 ________MADFDtyDDRAyssFGGGRGsRGsAGGHGsRSQ
Q15149 S4386 Sugiyama PLEC PLEC1 ItEFADMLsGNAGGFRsRsssVGssssyPIsPAVsRtQLAs
Q15293 Y278 Sugiyama RCN1 RCN LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE
Q15365 S27 Sugiyama PCBP1 ESGLNVTLTIRLLMHGKEVGsIIGKKGESVKRIREEsGARI
Q15365 S43 Sugiyama PCBP1 KEVGsIIGKKGESVKRIREEsGARINIsEGNCPERIItLTG
Q15365 S50 Sugiyama PCBP1 GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK
Q15365 T127 Sugiyama PCBP1 TQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT
Q15366 S27 Sugiyama PCBP2 EGGLNVTLTIRLLMHGKEVGsIIGKKGESVKKMREESGARI
Q15366 S50 Sugiyama PCBP2 GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK
Q15366 T127 Sugiyama PCBP2 sQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT
Q15428 S153 Sugiyama SF3A2 SAP62 LFQIDYPEIAEGIMPRHRFMsAyEQRIEPPDRRWQYLLMAA
Q15428 Y155 Sugiyama SF3A2 SAP62 QIDYPEIAEGIMPRHRFMsAyEQRIEPPDRRWQYLLMAAEP
Q15785 S186 Sugiyama TOMM34 URCC3 HKEMAKSKSKETTATKNRVPsAGDVEKARVLKEEGNELVKK
Q15811 S315 Sugiyama ITSN1 ITSN SH3D1A LPPVLPPEYIPPSFRRVRsGsGIsVIsSTSVDQRLPEEPVL
Q15831 S334 PSP STK11 LKB1 PJS PPAEAPVPIPPsPDTKDRWRsMtVVPYLEDLHGADEDEDLF
Q16576 S163 Sugiyama RBBP7 RBAP46 tPssDVLVFDyTKHPAKPDPsGECNPDLRLRGHQKEGYGLS
Q16637 S28 Sugiyama SMN1 SMN SMNT; SMN2 SMNC sGGGVPEQEDsVLFRRGtGQsDDsDIWDDtALIKAYDKAVA
Q16637 S31 Sugiyama SMN1 SMN SMNT; SMN2 SMNC GVPEQEDsVLFRRGtGQsDDsDIWDDtALIKAYDKAVAsFK
Q16658 S156 Sugiyama FSCN1 FAN1 HSN SNL IAMHPQVNIYSVTRKRYAHLsARPADEIAVDRDVPWGVDSL
Q16658 S234 Sugiyama FSCN1 FAN1 HSN SNL LEFRsGKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELF
Q16665 T455 SIGNOR|PSP HIF1A BHLHE78 MOP1 PASD8 MLPSPNEKLQNINLAMsPLPtAETPKPLRSsADPALNQEVA
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q16778 S37 Sugiyama H2BC21 H2BFQ HIST2H2BE KAVTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIss
Q27J81 T1206 Sugiyama INF2 C14orf151 C14orf173 DtsLDKsFsEDAVtDssGsGtLPRARGRASKGTGKRRKKRP
Q32P28 T655 Sugiyama P3H1 GROS1 LEPRE1 PSEC0109 KTVTAEVQPQCGRAVGFSSGtENPHGVKAVTRGQRCAIALW
Q4G0J3 S300 Sugiyama LARP7 HDCMA18P DRVEAssLPEVRTGKRKRsssEDAEsLAPRSKVKKIIQKDI
Q53EL6 S94 Sugiyama PDCD4 H731 GDsVsDsGsDALRSGLtVPtsPKGRLLDRRSRSGKGRGLPK
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q5BKZ1 Y93 Sugiyama ZNF326 ZIRD PYESyDsRsSLGGRDLYRsGyGFNEPEQSRFGGSYGGRFES
Q5JQF8 S87 Sugiyama PABPC1L2A PABPC1L2 RBM32A; PABPC1L2B PABPC1L2 RBM32B VIKGRPVRIMWSQRDPsLRKsGVGNVFIKNLGKTIDNKALY
Q5JSH3 T746 Sugiyama WDR44 RPH11 YHTQIHVRSTRGRNKVGRKItGIEPLPGENKILVTSNDSRI
Q5QNW6 S37 Sugiyama H2BC18 HIST2H2BF KAVTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q5QNW6 Y38 Sugiyama H2BC18 HIST2H2BF AVTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q5T5C0 S692 Sugiyama STXBP5 LLGL3 YGSNDPYRREPRSPRKsRQPsGAGLCDIsEGtVVPEDRCKS
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q6DN03 S37 Sugiyama H2BC20P HIST2H2BC KAVTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWC
Q6DRA6 S37 Sugiyama H2BC19P HIST2H2BD KAVTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWC
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6PEY2 S54 Sugiyama TUBA3E GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q6S8J3 S1065 Sugiyama POTEE A26C1A POTE2 ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UWE0 S158 Sugiyama LRSAM1 TAL UNQ6496/PRO21356 KLKELPDTVGELRSLRTLNIsGNEIQRLPQMLAHVRTLEML
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36 S54 Sugiyama TUBA1A TUBA3 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7L2J0 S216 Sugiyama MEPCE BCDIN3 NLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDIt
Q7L2J0 T213 Sugiyama MEPCE BCDIN3 DPLNLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPK
Q7L5Y9 S226 Sugiyama MAEA EMP HLC10 PIG5 IELIRQNKRLDAVRHARKHFsQAEGSQLDEVRQAMGMLAFP
Q86V81 S239 Sugiyama ALYREF ALY BEF THOC4 tRGGARGRGRGAGRNSKQQLsAEELDAQLDAyNARMDts__
Q8IXK0 S754 Sugiyama PHC2 EDR2 PH2 QEDssRCSDNSSYEEPLsPIsASSSTSRRRQGQRDLELPDM
Q8IYE1 S680 Sugiyama CCDC13 LTTRLAIQVEENEMLKAALGsALRGKEEDFRMYHEILGQVK
Q8N0Y7 T96 Sugiyama PGAM4 PGAM3 QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR
Q8N1G4 T27 Sugiyama LRRC47 KIAA1185 SESWPELELAERERRRELLLtGPGLEERVRAAGGQLPPRLF
Q8N257 S37 Sugiyama H2BC26 H2BU1 HIST3H2BB KAVTKAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIss
Q8N684 S166 Sugiyama CPSF7 PGKVLNGEKVDVRPAtRQNLsQFEAQARKRECVRVPRGGIP
Q8N684 S197 Sugiyama CPSF7 CVRVPRGGIPPRAHsRDssDsADGRAtPsENLVPSSARVDK
Q8N684 S205 Sugiyama CPSF7 IPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLPYF
Q8N806 S411 Sugiyama UBR7 C14orf130 ADEGTVVKREDIQQFFEEFQsKKRRRVDGMQYYCS______
Q8NBJ7 T272 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 LRGAsWIDtADGsANHRARVttRMGNtPDsAsDNLGFRCAA
Q8NBP7 S485 Sugiyama PCSK9 NARC1 PSEC0052 SGPTRMATAVARCAPDEELLsCssFSRSGKRRGERMEAQGG
Q8NBS9 S255 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 EHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDGKKVD
Q8TA86 S212 SIGNOR RP9 EKHKKRKKEKKKKKKRKHKSsKsNEGSDSE___________
Q8TA86 S214 SIGNOR RP9 HKKRKKEKKKKKKRKHKSsKsNEGSDSE_____________
Q8TC07 S675 Sugiyama TBC1D15 TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____
Q8TCD5 S182 Sugiyama NT5C DNT1 UMPH2 LFTCCHNRHLVLPPTRRRLLsWsDNWREILDSKRGAAQRE_
Q8TD16 S658 Sugiyama BICD2 KIAA0699 IKHLQAAVDRTTELSRQRIAsQELGPAVDKDKEALMEEILK
Q8TD47 T247 Sugiyama RPS4Y2 RPS4Y2P VIGNGNKPWISLPRGKGIRLtIAEERDKRLAAKQSSG____
Q8TDD1 S587 Sugiyama DDX54 KNYRSRATIFEINAsSRDLCsQVMRAKRQKDRKAIARFQQG
Q8TEW0 S837 Sugiyama PARD3 PAR3 PAR3A AFQREGFGRQsMsEKRtKQFsDAsQLDFVKTRKsKsMDLGI
Q8TEW0 Y719 Sugiyama PARD3 PAR3 PAR3A PELPIETALDDRERRIsHsLysGIEGLDEsPsRNAALsRIM
Q8WUX9 T408 Sugiyama CHMP7 LQDTTKEPLDLPDNPRNRHFtNsVPNPRIsDAELEAELEKL
Q8WZA9 S538 Sugiyama IRGQ IRGQ1 FKSG27 RGLGLEPTALARRERALGLAsGELAARAHFPGPVTRAEVEA
Q92597 S330 PSP|Sugiyama NDRG1 CAP43 DRG1 RTP QGMGYMPsAsMtRLMRsRtAsGssVtsLDGtRsRsHtSEGT
Q92597 T328 Sugiyama NDRG1 CAP43 DRG1 RTP FVQGMGYMPsAsMtRLMRsRtAsGssVtsLDGtRsRsHtSE
Q92597 T366 Sugiyama NDRG1 CAP43 DRG1 RTP tSEGTRsRsHtsEGtRsRsHtsEGAHLDItPNsGAAGNsAG
Q92734 S50 Sugiyama TFG DITyDELVLMMQRVFRGKLLsNDEVTIKYKDEDGDLITIFD
Q92766 S1167 Sugiyama RREB1 FINB AGTSKKRGRKRGMRSRPRANsGGVDLDssGEFASIEKMLAT
Q92785 S151 Sugiyama DPF2 BAF45D REQ UBID4 RGAPDPRVDDDsLGEFPVTNsRARKRILEPDDFLDDLDDED
Q92888 S545 Sugiyama ARHGEF1 QLKAKQRKDPRFCAFVQEAEsRPRCRRLQLKDMIPTEMQRL
Q92890 S294 Sugiyama UFD1 UFD1L SRPLVKKVEEDEAGGRFVAFsGEGQsLRKKGRKP_______
Q92890 S299 Sugiyama UFD1 UFD1L KKVEEDEAGGRFVAFsGEGQsLRKKGRKP____________
Q92934 S118 SIGNOR|iPTMNet BAD BBC6 BCL2L8 RsAPPNLWAAQRYGRELRRMsDEFVDsFKKGLPRPKsAGtA
Q92934 S75 SIGNOR|iPTMNet|PSP BAD BBC6 BCL2L8 PTSSSHHGGAGAVEIRsRHssyPAGtEDDEGMGEEPsPFRG
Q92934 S99 SIGNOR|iPTMNet BAD BBC6 BCL2L8 GtEDDEGMGEEPsPFRGRsRsAPPNLWAAQRYGRELRRMsD
Q93079 S37 Sugiyama H2BC9 H2BFJ HIST1H2BH KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q93079 Y38 Sugiyama H2BC9 H2BFJ HIST1H2BH AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q969S3 S38 Sugiyama ZNF622 ZPR9 MQRAHYKTDWHRYNLRRKVAsMAPVTAEGFQERVRAQRAVA
Q96B36 T246 GPS6 AKT1S1 PRAS40 VLREAEDtQVFGDLPRPRLNtsDFQKLKRKY__________
Q96C19 S74 Sugiyama EFHD2 SWS1 ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI
Q96G46 S236 Sugiyama DUS3L QQLRKREVRFERAEQALRRFsQGPtPAAAVPEGTAAEGAPR
Q96I99 S98 Sugiyama SUCLG2 KEIVLKAQILAGGRGKGVFNsGLKGGVHLTKDPNVVGQLAK
Q96N67 S1432 Sugiyama DOCK7 KIAA1771 RRSRGQLGTYTIAsPPERsPsGsAFGsQENLRWRKDMTHWR
Q96RE7 S330 Sugiyama NACC1 BTBD14B NAC1 MNVGQTAEKVEALPEQVAPEsRNRIRVRQDLASLPAELINQ
Q96S44 T8 Sugiyama TP53RK C20orf64 PRPK _____________MAAARAttPADGEEPAPEAEALAAARER
Q99543 S47 Sugiyama DNAJC2 MPHOSPH11 MPP11 ZRF1 QVEPVGRWFEAFVKRRNRNAsAsFQELEDKKELsEEsEDEE
Q99613 S639 Sugiyama EIF3C EIF3S8 CAFRQGLTKDAHNALLDIQssGRAKELLGQGLLLRSLQERN
Q99613 T157 Sugiyama EIF3C EIF3S8 ALSTLRQKIRKyNRDFEsHItSyKQNPEQsADEDAEKNEED
Q99615 S449 Sugiyama DNAJC7 TPR2 TTC2 KEVGEAFTILSDPKKKtRYDsGQDLDEEGMNMGDFDPNNIF
Q99683 S83 SIGNOR|PSP MAP3K5 ASK1 MAPKKK5 MEKK5 PGIGCPAATSSSSATRGRGSsVGGGSRRTTVAYVINEASQG
Q99733 T111 Sugiyama NAP1L4 NAP2 LERKyAALyQPLFDKRREFItGDVEPtDAEsEWHsENEEEE
Q99801 S185 PSP NKX3-1 NKX3.1 NKX3A EtQVKIWFQNRRYKTKRKQLssELGDLEKHssLPALKEEAF
Q99801 S186 PSP NKX3-1 NKX3.1 NKX3A tQVKIWFQNRRYKTKRKQLssELGDLEKHssLPALKEEAFS
Q99801 S195 PSP NKX3-1 NKX3.1 NKX3A RRYKTKRKQLssELGDLEKHssLPALKEEAFSRASLVSVYN
Q99801 S196 PSP NKX3-1 NKX3.1 NKX3A RYKTKRKQLssELGDLEKHssLPALKEEAFSRASLVSVYNS
Q99801 T89 PSP NKX3-1 NKX3.1 NKX3A AGAQNDQLSTGPRAAPEEAEtLAEtEPERHLGSYLLDSENT
Q99814 S435 SIGNOR|PSP EPAS1 BHLHE73 HIF2A MOP2 PASD2 DFGNQNFEESSAYGKAILPPsQPWATELRSHSTQSEAGSLP
Q99832 S59 Sugiyama CCT7 CCTH NIP7-1 TLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTL
Q99832 T362 Sugiyama CCT7 CCTH NIP7-1 LGRCQVFEEtQIGGERyNFFtGCPKAKTCtFILRGGAEQFM
Q99832 Y358 Sugiyama CCT7 CCTH NIP7-1 SADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCtFILRGGA
Q99877 S37 Sugiyama H2BC15 H2BFD HIST1H2BN KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q99877 Y38 Sugiyama H2BC15 H2BFD HIST1H2BN AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99879 S37 Sugiyama H2BC14 H2BFE HIST1H2BM KAINKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q99879 Y38 Sugiyama H2BC14 H2BFE HIST1H2BM AINKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q99880 S37 Sugiyama H2BC13 H2BFC HIST1H2BL KAVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIss
Q99880 Y38 Sugiyama H2BC13 H2BFC HIST1H2BL AVTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssK
Q9BQ52 S229 Sugiyama ELAC2 HPC2 PERssDsEsNENEPHLPHGVsQRRGVRDssLVVAFICKLHL
Q9BQE3 S54 Sugiyama TUBA1C TUBA6 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q9BTE6 S184 Sugiyama AARSD1 DRLPVNVRELsLDDPEVEQVsGRGLPDDHAGPIRVVNIEGV
Q9BTE6 S242 Sugiyama AARSD1 VIKILGTEKGKKNRTNLIFLsGNRVLKWMERSHGTEKALTA
Q9BUJ2 S512 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 IQIAARKKRNyILDQtNVyGsAQRRKMRPFEGFQRKAIVIC
Q9BYX7 S365 Sugiyama POTEKP ACTBL3 FKSG30 ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BZS1 S422 PSP FOXP3 IPEX JM2 KGAVWTVDELEFRKKRsQRPsRCSNPTPGP___________
Q9C0C2 S1103 Sugiyama TNKS1BP1 KIAA1741 TAB182 KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ
Q9C0C2 S672 Sugiyama TNKS1BP1 KIAA1741 TAB182 TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP
Q9H0A0 S593 Sugiyama NAT10 ALP KIAA1709 VLAVIQVCLEGEISRQSILNsLSRGKKASGDLIPWTVSEQF
Q9H4F8 T405 Sugiyama SMOC1 KPFKRYVKKKAKPKKCARRFtDyCDLNKDKVISLPELKGCL
Q9H6H4 S152 Sugiyama REEP4 C8orf20 PP432 AAVQAATKSQGALAGRLRsFsMQDLRSISDAPAPAyHDPLy
Q9H7D7 S121 Sugiyama WDR26 CDW2 MIP2 PRO0852 ASSSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLN
Q9HC52 S196 PSP CBX8 PC3 RC1 RERERGTSRVDDKPssPGDssKKRGPKPRKELPDPSQRPLG
Q9NR19 S30 Sugiyama ACSS2 ACAS2 sGsGSRGQEEAGAGGRARsWsPPPEVsRSAHVPSLQRYREL
Q9NRL2 S286 Sugiyama BAZ1A ACF1 WCRF180 HSPC317 TFIFsPANRRRGRPPKRIHIsQEDNVANKQTLASYRSKATK
Q9NSE4 S98 Sugiyama IARS2 RQQPDtELEIQQKCGFSELysWQRERKVKTEFCLHDGPPYA
Q9NYV4 S1053 Sugiyama CDK12 CRK7 CRKRS KIAA0904 LPHWQDCHELWSKKRRRQRQsGVVVEEPPPSKTSRKETtsG
Q9NZN8 S242 Sugiyama CNOT2 CDC36 NOT2 HSPC131 MSTP046 VTGLDLSDFPALADRNRREGsGNPtPLINPLAGRAPYVGMV
Q9P032 S35 Sugiyama NDUFAF4 C6orf66 HRPAP20 HSPC125 My013 ENRAEREISKMKPSVAPRHPsTNSLLREQIsLyPEVKGEIA
Q9P2B2 S217 Sugiyama PTGFRN CD9P1 EWIF FPRP KIAA1436 LALTHEGRFHPGLGYEQRYHsGDVRLDTVGSDAYRLSVSRA
Q9UBP6 S27 Sugiyama METTL1 C12orf1 NVAGAEAPPPQKRYYRQRAHsNPMADHTLRYPVKPEEMDWS
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UG63 T307 Sugiyama ABCF2 HUSSY-18 FLNGVCTNIIHMHNKKLKYYtGNYDQYVKTRLELEENQMKR
Q9UGV2 S331 Sugiyama NDRG3 QGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQ
Q9UGV2 S333 Sugiyama NDRG3 MGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsD
Q9UGV2 T332 Sugiyama NDRG3 GMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQs
Q9UHI6 T748 Sugiyama DDX20 DP103 GEMIN3 SQRAKQSRRNLPRRSsFRLQtEAQEDDWyDCHREIRLSFSD
Q9UL25 S143 Sugiyama RAB21 KIAA0118 NEICLCIVGNKIDLEKERHVsIQEAESyAESVGAKHYHTSA
Q9ULD2 S1259 Sugiyama MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 LCsPKRsPtssAIPLQsPRNsGsFPsPsIsPR_________
Q9UNF1 S264 Sugiyama MAGED2 BCG1 sLRsPKARRGKARRRAAKLQssQEPEAPPPRDVALLQGRAN
Q9UNN5 S582 Sugiyama FAF1 UBXD12 UBXN3A CGI-03 PPEPKEENAEPVSKLRIRtPsGEFLERRFLASNKLQIVFDF
Q9UNQ0 T362 SIGNOR|PSP ABCG2 ABCP BCRP BCRP1 MXR YKETKAELHQLsGGEKKKKItVFKEISYTTSFCHQLRWVSK
Q9UNX3 S12 Sugiyama RPL26L1 RPL26P1 _________MKFNPFVtsDRsKNRKRHFNAPSHVRRKIMss
Q9UQ35 S1648 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 APRALPRRSRSGSSSKGRGPsPEGssstEssPEHPPKSRTA
Q9UQ80 S267 Sugiyama PA2G4 EBP1 YKRDPSKQYGLKMKtSRAFFsEVERRFDAMPFtLRAFEDEK
Q9UQ80 S335 Sugiyama PA2G4 EBP1 FVAQFKFTVLLMPNGPMRITsGPFEPDLyKsEMEVQDAELK
Q9UQ80 T377 Sugiyama PA2G4 EBP1 LLQssAsRKtQKKKKKKAsKtAENAtsGEtLEENEAGD___
Q9Y262 S249 Sugiyama EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 NVLHSLVDKSNINRQLEVytsGGDPEsVAGEyGRHSLYKML
Q9Y2B0 S116 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2I7 S307 Sugiyama PIKFYVE KIAA0981 PIP5K3 TRLVSVQEDAGKsPARNRsAsItNLsLDRsGsPMVPSYEts
Q9Y3F4 S254 Sugiyama STRAP MAWD UNRIP EKEFLVAGGEDFKLyKyDyNsGEELEsyKGHFGPIHCVRFS
Q9Y4H2 S1149 PSP IRS2 PHRGAKVIRADPQGGRRRHssEtFsstttVtPVsPsFAHNP
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y697 S283 Sugiyama NFS1 NIFS HUSSY-08 KGVGAIYIRRRPRVRVEALQsGGGQERGMRsGTVPTPLVVG
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Gene expression (Transcription) R-HSA-74160 2.240505e-07 6.650 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.197763e-07 6.495 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 3.915247e-07 6.407 0 0
Chromatin organization R-HSA-4839726 5.235308e-07 6.281 0 0
RNA Polymerase II Transcription R-HSA-73857 5.100830e-07 6.292 0 0
mRNA Splicing R-HSA-72172 7.415567e-07 6.130 0 0
Chromatin modifying enzymes R-HSA-3247509 2.345087e-06 5.630 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 6.580071e-06 5.182 0 0
Apoptotic execution phase R-HSA-75153 7.071097e-06 5.151 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.383411e-05 4.859 0 0
Signal Transduction R-HSA-162582 1.598886e-05 4.796 0 0
G alpha (12/13) signalling events R-HSA-416482 2.613058e-05 4.583 0 0
Generic Transcription Pathway R-HSA-212436 2.505665e-05 4.601 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.021954e-04 3.991 0 0
mRNA 3'-end processing R-HSA-72187 9.571748e-05 4.019 0 0
Axon guidance R-HSA-422475 9.919356e-05 4.004 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.174856e-04 3.930 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.361223e-04 3.866 0 0
NRAGE signals death through JNK R-HSA-193648 2.259894e-04 3.646 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.399141e-04 3.620 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.579168e-04 3.446 1 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 3.666805e-04 3.436 0 0
Death Receptor Signaling R-HSA-73887 4.234949e-04 3.373 0 0
Nervous system development R-HSA-9675108 4.472917e-04 3.349 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 6.736906e-04 3.172 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 7.061269e-04 3.151 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 6.986284e-04 3.156 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 7.317477e-04 3.136 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 8.287014e-04 3.082 0 0
Regulation of TP53 Activity R-HSA-5633007 8.094131e-04 3.092 0 0
Metabolism of RNA R-HSA-8953854 8.679532e-04 3.062 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.013525e-03 2.994 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.229446e-03 2.910 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.308120e-03 2.883 0 0
Germ layer formation at gastrulation R-HSA-9754189 1.797732e-03 2.745 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.719798e-03 2.765 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.849136e-03 2.733 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.277678e-03 2.643 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 2.869739e-03 2.542 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 3.122868e-03 2.505 0 0
Signaling by Hippo R-HSA-2028269 3.355914e-03 2.474 0 0
Specification of primordial germ cells R-HSA-9827857 3.355914e-03 2.474 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 3.400288e-03 2.468 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.730146e-03 2.428 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.473731e-03 2.349 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 4.473731e-03 2.349 0 0
Activation of RAC1 R-HSA-428540 4.612027e-03 2.336 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 4.672129e-03 2.330 0 0
HATs acetylate histones R-HSA-3214847 4.802286e-03 2.319 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 4.856917e-03 2.314 0 0
Signaling by ROBO receptors R-HSA-376176 5.073398e-03 2.295 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 5.612224e-03 2.251 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 7.446219e-03 2.128 0 0
Signaling downstream of RAS mutants R-HSA-9649948 7.446219e-03 2.128 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 7.446219e-03 2.128 0 0
Signaling by RAS mutants R-HSA-6802949 7.446219e-03 2.128 0 0
Signaling by RAF1 mutants R-HSA-9656223 7.564296e-03 2.121 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 7.581744e-03 2.120 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 9.192235e-03 2.037 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 9.015973e-03 2.045 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 8.880097e-03 2.052 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 8.880097e-03 2.052 0 0
Semaphorin interactions R-HSA-373755 8.836061e-03 2.054 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.024487e-02 1.989 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.024487e-02 1.989 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.277612e-02 1.894 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.242458e-02 1.906 0 0
Nuclear Receptor transcription pathway R-HSA-383280 1.425034e-02 1.846 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.535360e-02 1.814 0 0
p75NTR signals via NF-kB R-HSA-193639 1.538610e-02 1.813 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.681489e-02 1.774 0 0
MAP2K and MAPK activation R-HSA-5674135 1.697968e-02 1.770 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 1.721211e-02 1.764 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.760425e-02 1.754 0 0
Cardiogenesis R-HSA-9733709 1.804949e-02 1.744 0 0
Adrenoceptors R-HSA-390696 1.728440e-02 1.762 0 0
Nuclear RNA decay R-HSA-9930044 1.804949e-02 1.744 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.970357e-02 1.705 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.081626e-02 1.682 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.060113e-02 1.686 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 2.009582e-02 1.697 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 2.219725e-02 1.654 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.119539e-02 1.674 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.168817e-02 1.664 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 2.219725e-02 1.654 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 2.219246e-02 1.654 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 2.362760e-02 1.627 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 2.362760e-02 1.627 0 0
PIP3 activates AKT signaling R-HSA-1257604 2.268992e-02 1.644 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.362760e-02 1.627 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.267336e-02 1.644 0 0
ALK mutants bind TKIs R-HSA-9700645 2.400147e-02 1.620 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 2.400147e-02 1.620 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 2.400147e-02 1.620 0 0
Diseases of Telomere Maintenance R-HSA-9673013 3.004175e-02 1.522 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 3.004175e-02 1.522 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 3.004175e-02 1.522 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 3.004175e-02 1.522 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 3.004175e-02 1.522 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 3.050575e-02 1.516 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 2.863315e-02 1.543 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 3.072344e-02 1.513 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 3.133114e-02 1.504 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 3.050575e-02 1.516 0 0
TRP channels R-HSA-3295583 3.094631e-02 1.509 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.130784e-02 1.504 0 0
CREB phosphorylation R-HSA-199920 3.415984e-02 1.466 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.415984e-02 1.466 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 3.220226e-02 1.492 0 0
Intracellular signaling by second messengers R-HSA-9006925 3.282339e-02 1.484 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 3.232291e-02 1.490 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 3.489693e-02 1.457 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 3.755909e-02 1.425 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 3.909442e-02 1.408 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.609971e-02 1.442 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 3.755909e-02 1.425 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 3.762512e-02 1.425 0 0
Integrin signaling R-HSA-354192 4.039950e-02 1.394 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 4.039950e-02 1.394 0 0
DCC mediated attractive signaling R-HSA-418885 4.491522e-02 1.348 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 4.229689e-02 1.374 0 0
Estrogen-dependent gene expression R-HSA-9018519 4.323533e-02 1.364 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 4.558952e-02 1.341 0 0
Rap1 signalling R-HSA-392517 4.530541e-02 1.344 0 0
Signaling by NTRKs R-HSA-166520 4.428345e-02 1.354 0 0
Formation of the anterior neural plate R-HSA-9823739 4.491522e-02 1.348 0 0
Signaling by Interleukins R-HSA-449147 4.226651e-02 1.374 1 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 4.701992e-02 1.328 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 4.701992e-02 1.328 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 4.701992e-02 1.328 0 0
MECP2 regulates transcription factors R-HSA-9022707 4.701992e-02 1.328 0 0
MTF1 activates gene expression R-HSA-5660489 4.787016e-02 1.320 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 5.076955e-02 1.294 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 5.076955e-02 1.294 0 0
Netrin-1 signaling R-HSA-373752 5.137130e-02 1.289 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 4.787016e-02 1.320 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 4.787016e-02 1.320 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.979691e-02 1.303 0 0
Dopamine receptors R-HSA-390651 4.787016e-02 1.320 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 4.787016e-02 1.320 0 0
Cell Cycle R-HSA-1640170 5.239743e-02 1.281 0 0
MITF-M-dependent gene expression R-HSA-9856651 5.021204e-02 1.299 0 0
NF-kB is activated and signals survival R-HSA-209560 5.332250e-02 1.273 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 5.332250e-02 1.273 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 5.364138e-02 1.271 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.484776e-02 1.261 0 0
HDMs demethylate histones R-HSA-3214842 6.042392e-02 1.219 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 6.198375e-02 1.208 0 0
Signaling by TGFB family members R-HSA-9006936 6.210161e-02 1.207 0 0
Type I hemidesmosome assembly R-HSA-446107 6.220764e-02 1.206 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 6.220764e-02 1.206 0 0
EPH-Ephrin signaling R-HSA-2682334 6.271740e-02 1.203 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 6.908328e-02 1.161 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 6.908328e-02 1.161 0 0
p75NTR recruits signalling complexes R-HSA-209543 6.629934e-02 1.178 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 6.629934e-02 1.178 0 0
Neurexins and neuroligins R-HSA-6794361 6.505040e-02 1.187 0 0
RET signaling R-HSA-8853659 6.795992e-02 1.168 0 0
Signaling by FGFR1 in disease R-HSA-5655302 6.996754e-02 1.155 0 0
NrCAM interactions R-HSA-447038 6.908328e-02 1.161 0 0
Interleukin-12 signaling R-HSA-9020591 6.497537e-02 1.187 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.253157e-01 0.902 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.253157e-01 0.902 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.253157e-01 0.902 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.253157e-01 0.902 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.253157e-01 0.902 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.253157e-01 0.902 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.253157e-01 0.902 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.011527e-01 0.995 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.011527e-01 0.995 0 0
Regulation of cortical dendrite branching R-HSA-8985801 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.011527e-01 0.995 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.011527e-01 0.995 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.011527e-01 0.995 0 0
Defective Mismatch Repair Associated With PMS2 R-HSA-5632987 2.349337e-01 0.629 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 2.349337e-01 0.629 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 2.349337e-01 0.629 0 0
Defective Mismatch Repair Associated With MLH1 R-HSA-5545483 2.349337e-01 0.629 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 2.349337e-01 0.629 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 2.349337e-01 0.629 0 0
Axonal growth stimulation R-HSA-209563 1.452373e-01 0.838 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 9.378880e-02 1.028 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 9.378880e-02 1.028 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 9.378880e-02 1.028 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 9.378880e-02 1.028 0 0
Regulated proteolysis of p75NTR R-HSA-193692 7.966169e-02 1.099 0 0
Calcineurin activates NFAT R-HSA-2025928 7.966169e-02 1.099 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 1.215491e-01 0.915 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 1.215491e-01 0.915 0 0
Regulation of gap junction activity R-HSA-191650 1.923917e-01 0.716 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 1.923917e-01 0.716 0 0
NADE modulates death signalling R-HSA-205025 1.923917e-01 0.716 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 1.923917e-01 0.716 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.923917e-01 0.716 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 1.923917e-01 0.716 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 1.923917e-01 0.716 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.923917e-01 0.716 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 3.308197e-01 0.480 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 3.308197e-01 0.480 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 3.308197e-01 0.480 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 3.308197e-01 0.480 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 3.308197e-01 0.480 0 0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 3.308197e-01 0.480 0 0
TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P R-HSA-6791462 3.308197e-01 0.480 0 0
TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P R-HSA-6791055 3.308197e-01 0.480 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 3.308197e-01 0.480 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 3.308197e-01 0.480 0 0
IKBKB deficiency causes SCID R-HSA-5602636 3.308197e-01 0.480 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 3.308197e-01 0.480 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 3.308197e-01 0.480 0 0
Regulation of PTEN localization R-HSA-8948747 1.518848e-01 0.818 0 0
SOS-mediated signalling R-HSA-112412 1.518848e-01 0.818 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.518848e-01 0.818 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 8.087665e-02 1.092 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 1.208765e-01 0.918 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.411551e-01 0.618 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.411551e-01 0.618 0 0
IRS activation R-HSA-74713 2.411551e-01 0.618 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.411551e-01 0.618 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.411551e-01 0.618 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.411551e-01 0.618 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 9.701277e-02 1.013 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 7.839068e-02 1.106 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 1.843045e-01 0.734 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 1.843045e-01 0.734 0 0
RSK activation R-HSA-444257 1.843045e-01 0.734 0 0
Formation of annular gap junctions R-HSA-196025 1.843045e-01 0.734 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.442975e-01 0.841 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.146424e-01 0.941 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.146424e-01 0.941 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 1.067783e-01 0.972 0 0
Differentiation of T cells R-HSA-9945266 1.336796e-01 0.874 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 1.336796e-01 0.874 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.693242e-01 0.771 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 1.693242e-01 0.771 0 0
IRAK1 recruits IKK complex R-HSA-937039 1.693242e-01 0.771 0 0
p75NTR regulates axonogenesis R-HSA-193697 2.183253e-01 0.661 0 0
Lipophagy R-HSA-9613354 2.183253e-01 0.661 0 0
Gap junction degradation R-HSA-190873 2.183253e-01 0.661 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 2.183253e-01 0.661 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.903843e-01 0.537 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 2.903843e-01 0.537 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 2.903843e-01 0.537 0 0
GLI proteins bind promoters of Hh responsive genes to promote transcription R-HSA-5635851 2.903843e-01 0.537 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.903843e-01 0.537 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.903843e-01 0.537 0 0
Signaling by MAPK mutants R-HSA-9652817 2.903843e-01 0.537 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 2.903843e-01 0.537 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 4.146931e-01 0.382 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 4.146931e-01 0.382 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 4.146931e-01 0.382 0 0
HHAT G278V doesn't palmitoylate Hh-Np R-HSA-5658034 4.146931e-01 0.382 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 4.146931e-01 0.382 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 4.146931e-01 0.382 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) R-HSA-5619049 4.146931e-01 0.382 0 0
Potassium transport channels R-HSA-1296067 4.146931e-01 0.382 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.227114e-01 0.911 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 1.227114e-01 0.911 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 1.227114e-01 0.911 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 1.227114e-01 0.911 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 1.227114e-01 0.911 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 1.540214e-01 0.812 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.540214e-01 0.812 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 1.540214e-01 0.812 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.957341e-01 0.708 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.957341e-01 0.708 0 0
Deadenylation of mRNA R-HSA-429947 1.122210e-01 0.950 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 8.327751e-02 1.079 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 2.534883e-01 0.596 0 0
PI3K/AKT activation R-HSA-198203 2.534883e-01 0.596 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 2.534883e-01 0.596 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 2.534883e-01 0.596 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 1.024721e-01 0.989 0 0
TGFBR3 expression R-HSA-9839394 1.267415e-01 0.897 0 0
Tight junction interactions R-HSA-420029 1.267415e-01 0.897 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.577887e-01 0.802 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 3.391973e-01 0.470 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.421575e-01 0.847 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.981414e-01 0.703 0 0
Ephrin signaling R-HSA-3928664 1.981414e-01 0.703 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 1.981414e-01 0.703 0 0
ChREBP activates metabolic gene expression R-HSA-163765 2.893677e-01 0.539 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 2.893677e-01 0.539 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.052350e-01 0.978 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.584254e-01 0.800 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.584254e-01 0.800 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.517842e-01 0.599 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 2.517842e-01 0.599 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.216577e-01 0.654 0 0
Regulation of PTEN gene transcription R-HSA-8943724 7.879741e-02 1.103 0 0
HIV elongation arrest and recovery R-HSA-167287 1.754948e-01 0.756 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.754948e-01 0.756 0 0
Striated Muscle Contraction R-HSA-390522 1.727979e-01 0.762 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.727979e-01 0.762 0 0
Late endosomal microautophagy R-HSA-9615710 1.933096e-01 0.714 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.173322e-01 0.663 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 2.173322e-01 0.663 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 3.255770e-01 0.487 0 0
ERKs are inactivated R-HSA-202670 3.255770e-01 0.487 0 0
Signaling by GSK3beta mutants R-HSA-5339716 3.255770e-01 0.487 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 3.869254e-01 0.412 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.869254e-01 0.412 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 3.869254e-01 0.412 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.869254e-01 0.412 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.869254e-01 0.412 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 3.869254e-01 0.412 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 3.869254e-01 0.412 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 4.880582e-01 0.312 0 0
TFAP2 (AP-2) family regulates transcription of other transcription factors R-HSA-8866906 4.880582e-01 0.312 0 0
MET activates PTPN11 R-HSA-8865999 4.880582e-01 0.312 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 4.880582e-01 0.312 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 4.880582e-01 0.312 0 0
Invadopodia formation R-HSA-8941237 4.880582e-01 0.312 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.693054e-01 0.771 0 0
RAF activation R-HSA-5673000 1.889723e-01 0.724 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 1.889723e-01 0.724 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 1.889723e-01 0.724 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 2.118086e-01 0.674 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.118086e-01 0.674 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 2.386844e-01 0.622 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 2.709106e-01 0.567 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.283961e-01 0.891 0 0
Downstream signal transduction R-HSA-186763 2.309269e-01 0.637 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.995097e-01 0.700 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 3.617720e-01 0.442 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 3.617720e-01 0.442 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.617720e-01 0.442 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 3.617720e-01 0.442 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 3.617720e-01 0.442 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 3.617720e-01 0.442 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 3.617720e-01 0.442 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 3.617720e-01 0.442 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 2.231026e-01 0.651 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.343606e-01 0.872 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.963662e-01 0.528 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.963662e-01 0.528 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.636155e-01 0.786 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.636155e-01 0.786 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 2.830802e-01 0.548 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 2.830802e-01 0.548 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 4.330741e-01 0.363 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 4.330741e-01 0.363 0 0
Regulation by c-FLIP R-HSA-3371378 4.330741e-01 0.363 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 4.330741e-01 0.363 0 0
Dimerization of procaspase-8 R-HSA-69416 4.330741e-01 0.363 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 4.330741e-01 0.363 0 0
FGFR1b ligand binding and activation R-HSA-190370 4.330741e-01 0.363 0 0
Activation of RAS in B cells R-HSA-1169092 4.330741e-01 0.363 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 4.330741e-01 0.363 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 4.330741e-01 0.363 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.355178e-01 0.868 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.355178e-01 0.868 0 0
Centrosome maturation R-HSA-380287 1.537217e-01 0.813 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 2.317715e-01 0.635 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 2.707459e-01 0.567 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.398659e-01 0.854 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 3.059294e-01 0.514 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 3.976517e-01 0.400 0 0
Formation of axial mesoderm R-HSA-9796292 3.976517e-01 0.400 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.913043e-01 0.536 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 2.779947e-01 0.556 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.482499e-01 0.458 0 0
Signaling by Erythropoietin R-HSA-9006335 3.290841e-01 0.483 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 3.290841e-01 0.483 0 0
HIV Transcription Elongation R-HSA-167169 2.970617e-01 0.527 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 2.970617e-01 0.527 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 2.970617e-01 0.527 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.860854e-01 0.730 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.916562e-01 0.717 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.916562e-01 0.717 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 3.011706e-01 0.521 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.524496e-01 0.453 0 0
DAP12 signaling R-HSA-2424491 3.524496e-01 0.453 0 0
Regulation of signaling by CBL R-HSA-912631 4.004783e-01 0.397 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 4.004783e-01 0.397 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 4.772897e-01 0.321 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 4.772897e-01 0.321 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 4.772897e-01 0.321 0 0
WNT mediated activation of DVL R-HSA-201688 4.772897e-01 0.321 0 0
CASP8 activity is inhibited R-HSA-5218900 4.772897e-01 0.321 0 0
TNFR1-mediated ceramide production R-HSA-5626978 5.522312e-01 0.258 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 5.522312e-01 0.258 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 5.522312e-01 0.258 0 0
Signaling by MAP2K mutants R-HSA-9652169 5.522312e-01 0.258 0 0
Defective CP causes aceruloplasminemia (ACERULOP) R-HSA-5619060 5.522312e-01 0.258 0 0
EGFR downregulation R-HSA-182971 3.759344e-01 0.425 0 0
Trafficking of AMPA receptors R-HSA-399719 3.759344e-01 0.425 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.712945e-01 0.567 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 4.301253e-01 0.366 0 0
Transcription of the HIV genome R-HSA-167172 3.231231e-01 0.491 0 0
Erythropoietin activates RAS R-HSA-9027284 4.674724e-01 0.330 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 4.674724e-01 0.330 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 4.674724e-01 0.330 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 4.674724e-01 0.330 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 4.674724e-01 0.330 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 3.387062e-01 0.470 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 4.593656e-01 0.338 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 5.193319e-01 0.285 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 5.193319e-01 0.285 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 5.193319e-01 0.285 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 3.361073e-01 0.474 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.524055e-01 0.344 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.480528e-01 0.458 0 0
Phosphorylation of the APC/C R-HSA-176412 5.010161e-01 0.300 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.010161e-01 0.300 0 0
snRNP Assembly R-HSA-191859 4.086970e-01 0.389 0 0
Metabolism of non-coding RNA R-HSA-194441 4.086970e-01 0.389 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.591992e-01 0.445 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 4.778840e-01 0.321 0 0
Formation of the Early Elongation Complex R-HSA-113418 4.778840e-01 0.321 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 4.693726e-01 0.328 0 0
Translation initiation complex formation R-HSA-72649 4.494796e-01 0.347 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 4.255376e-01 0.371 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.937331e-01 0.405 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.273336e-01 0.369 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.831176e-01 0.316 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 5.029533e-01 0.298 0 0
FGFR2 alternative splicing R-HSA-6803529 5.161331e-01 0.287 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 5.161331e-01 0.287 0 0
Notch-HLH transcription pathway R-HSA-350054 5.161331e-01 0.287 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 5.334446e-01 0.273 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 5.590509e-01 0.253 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 5.590509e-01 0.253 0 0
Signaling by APC mutants R-HSA-4839744 5.590509e-01 0.253 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 5.590509e-01 0.253 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 5.590509e-01 0.253 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 5.590509e-01 0.253 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 5.590509e-01 0.253 0 0
G2 Phase R-HSA-68911 6.083632e-01 0.216 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 6.083632e-01 0.216 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 6.083632e-01 0.216 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 6.083632e-01 0.216 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.083632e-01 0.216 0 0
Defective F9 activation R-HSA-9673221 6.083632e-01 0.216 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 6.083632e-01 0.216 0 0
Viral mRNA Translation R-HSA-192823 4.589507e-01 0.338 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 5.275370e-01 0.278 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 5.646455e-01 0.248 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 5.515678e-01 0.258 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 5.515678e-01 0.258 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 5.699590e-01 0.244 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 5.963685e-01 0.224 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 5.749876e-01 0.240 0 0
GAB1 signalosome R-HSA-180292 5.945354e-01 0.226 0 0
PKA activation in glucagon signalling R-HSA-164378 5.945354e-01 0.226 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.977468e-01 0.223 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 6.123516e-01 0.213 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.182954e-01 0.209 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 6.236567e-01 0.205 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 6.202688e-01 0.207 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 6.230559e-01 0.205 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.230559e-01 0.205 0 0
GRB2 events in EGFR signaling R-HSA-179812 6.312626e-01 0.200 0 0
Signaling by EGFR R-HSA-177929 3.558713e-01 0.449 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.064800e-01 0.685 0 0
Signaling by FGFR2 R-HSA-5654738 5.135249e-01 0.289 0 0
FOXO-mediated transcription R-HSA-9614085 1.093972e-01 0.961 0 0
Signaling by EGFR in Cancer R-HSA-1643713 6.202688e-01 0.207 0 0
Circadian clock R-HSA-9909396 5.136131e-01 0.289 0 0
ESR-mediated signaling R-HSA-8939211 1.888893e-01 0.724 0 0
RNA Polymerase III Transcription R-HSA-74158 2.231026e-01 0.651 0 0
Mitotic Prometaphase R-HSA-68877 2.713409e-01 0.566 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 4.593656e-01 0.338 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 4.593656e-01 0.338 0 0
Signaling by FGFR4 R-HSA-5654743 3.756788e-01 0.425 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.405600e-01 0.468 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.405600e-01 0.468 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.199159e-01 0.658 0 0
Specification of the neural plate border R-HSA-9834899 2.216577e-01 0.654 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 2.518159e-01 0.599 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 4.229138e-01 0.374 0 0
Recycling pathway of L1 R-HSA-437239 7.118505e-02 1.148 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.051264e-01 0.978 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.553902e-01 0.449 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 5.275370e-01 0.278 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.966713e-01 0.706 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 3.224121e-01 0.492 0 0
Signaling by FGFR3 R-HSA-5654741 4.156211e-01 0.381 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.730362e-01 0.762 0 0
Signaling by FGFR1 R-HSA-5654736 4.864958e-01 0.313 0 0
NGF-stimulated transcription R-HSA-9031628 1.371935e-01 0.863 0 0
Signaling by ERBB2 R-HSA-1227986 5.583238e-01 0.253 0 0
GP1b-IX-V activation signalling R-HSA-430116 2.183253e-01 0.661 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 3.106282e-01 0.508 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.234121e-01 0.909 0 0
IRS-mediated signalling R-HSA-112399 3.734103e-01 0.428 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.657736e-01 0.575 0 0
Synaptic adhesion-like molecules R-HSA-8849932 1.981414e-01 0.703 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 7.748480e-02 1.111 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 5.147438e-01 0.288 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.902656e-01 0.537 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 4.104936e-01 0.387 0 0
G-protein beta:gamma signalling R-HSA-397795 5.977468e-01 0.223 0 0
Aggrephagy R-HSA-9646399 6.004124e-01 0.222 0 0
Interleukin-1 signaling R-HSA-9020702 5.342380e-01 0.272 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 2.830802e-01 0.548 0 0
Myogenesis R-HSA-525793 4.266034e-01 0.370 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 4.593656e-01 0.338 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.566196e-01 0.448 0 0
G0 and Early G1 R-HSA-1538133 3.994504e-01 0.399 0 0
Frs2-mediated activation R-HSA-170968 1.957341e-01 0.708 0 0
TCR signaling R-HSA-202403 2.110842e-01 0.676 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 5.561810e-01 0.255 0 0
Co-stimulation by CD28 R-HSA-389356 3.376012e-01 0.472 0 0
Homology Directed Repair R-HSA-5693538 4.070743e-01 0.390 0 0
Formation of the posterior neural plate R-HSA-9832991 1.208765e-01 0.918 0 0
Pyroptosis R-HSA-5620971 9.072841e-02 1.042 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.231026e-01 0.651 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.788794e-01 0.747 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 4.772897e-01 0.321 0 0
PI3K Cascade R-HSA-109704 3.746999e-01 0.426 0 0
DNA Double Strand Break Response R-HSA-5693606 4.221775e-01 0.375 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 4.616098e-01 0.336 0 0
DARPP-32 events R-HSA-180024 5.029533e-01 0.298 0 0
Meiotic synapsis R-HSA-1221632 5.704231e-01 0.244 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.480528e-01 0.458 0 0
Generation of second messenger molecules R-HSA-202433 1.841320e-01 0.735 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 3.192796e-01 0.496 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 6.202688e-01 0.207 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.724232e-01 0.565 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.334446e-01 0.273 0 0
Hedgehog 'off' state R-HSA-5610787 6.240548e-01 0.205 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 4.234028e-01 0.373 0 0
MHC class II antigen presentation R-HSA-2132295 3.794708e-01 0.421 0 0
Signaling by PDGF R-HSA-186797 5.926519e-01 0.227 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.373626e-02 1.132 0 0
Regulation of CDH11 function R-HSA-9762292 2.534883e-01 0.596 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 3.405600e-01 0.468 0 0
Clathrin-mediated endocytosis R-HSA-8856828 1.428883e-01 0.845 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 4.772897e-01 0.321 0 0
Peptide chain elongation R-HSA-156902 2.347191e-01 0.629 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 4.693726e-01 0.328 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 3.562095e-01 0.448 0 0
TNF signaling R-HSA-75893 3.558713e-01 0.449 0 0
Regulated Necrosis R-HSA-5218859 2.249385e-01 0.648 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.557844e-01 0.449 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 5.701254e-01 0.244 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 6.278125e-01 0.202 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 8.327751e-02 1.079 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 5.275370e-01 0.278 0 0
Regulation of TNFR1 signaling R-HSA-5357905 3.011706e-01 0.521 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 6.117024e-01 0.213 0 0
M Phase R-HSA-68886 3.558064e-01 0.449 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.727979e-01 0.762 0 0
Formation of definitive endoderm R-HSA-9823730 4.301253e-01 0.366 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 4.880717e-01 0.312 0 0
IGF1R signaling cascade R-HSA-2428924 3.719118e-01 0.430 0 0
Insulin receptor signalling cascade R-HSA-74751 4.964791e-01 0.304 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 2.183253e-01 0.661 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.572775e-01 0.803 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 2.809672e-01 0.551 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 3.617720e-01 0.442 0 0
Sodium/Proton exchangers R-HSA-425986 4.330741e-01 0.363 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.916562e-01 0.717 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 6.083632e-01 0.216 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 5.475678e-01 0.262 0 0
PKA activation R-HSA-163615 5.945354e-01 0.226 0 0
Post NMDA receptor activation events R-HSA-438064 2.230040e-01 0.652 0 0
STING mediated induction of host immune responses R-HSA-1834941 1.067783e-01 0.972 0 0
TCF dependent signaling in response to WNT R-HSA-201681 2.463418e-01 0.608 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.122210e-01 0.950 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 2.809672e-01 0.551 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 4.791062e-01 0.320 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.334158e-01 0.875 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 1.421575e-01 0.847 1 1
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.533262e-01 0.814 0 0
Signal attenuation R-HSA-74749 2.534883e-01 0.596 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.414348e-01 0.849 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 2.057565e-01 0.687 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.779947e-01 0.556 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.701447e-01 0.769 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 3.121989e-01 0.506 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.329578e-01 0.364 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 3.041226e-01 0.517 0 0
Long-term potentiation R-HSA-9620244 4.005728e-01 0.397 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 2.241469e-01 0.649 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 6.312626e-01 0.200 0 0
Signaling by Nuclear Receptors R-HSA-9006931 5.350004e-01 0.272 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.334158e-01 0.875 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 1.559219e-01 0.807 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 2.592755e-01 0.586 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.741114e-01 0.759 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 5.193319e-01 0.285 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.026137e-01 0.519 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 5.519438e-01 0.258 0 0
MTOR signalling R-HSA-165159 7.793590e-02 1.108 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 1.559219e-01 0.807 0 0
Mitotic Anaphase R-HSA-68882 2.941660e-01 0.531 0 0
Prolonged ERK activation events R-HSA-169893 2.809672e-01 0.551 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 3.886242e-01 0.410 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 5.054169e-01 0.296 0 0
Cilium Assembly R-HSA-5617833 5.999849e-01 0.222 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.658145e-01 0.247 0 0
Mitotic Prophase R-HSA-68875 5.261910e-01 0.279 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 4.250818e-01 0.372 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 4.250818e-01 0.372 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.232977e-01 0.651 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.369721e-02 1.028 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 3.255770e-01 0.487 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 3.869254e-01 0.412 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.869254e-01 0.412 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 2.118086e-01 0.674 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 2.830802e-01 0.548 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 3.405600e-01 0.468 0 0
TGFBR3 PTM regulation R-HSA-9839383 4.330741e-01 0.363 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 2.707459e-01 0.567 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 3.976517e-01 0.400 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.916562e-01 0.717 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.145094e-01 0.669 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.227539e-01 0.652 0 0
Arachidonate production from DAG R-HSA-426048 5.193319e-01 0.285 0 0
Effects of PIP2 hydrolysis R-HSA-114508 4.462458e-01 0.350 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 3.990680e-01 0.399 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 4.693726e-01 0.328 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 6.083632e-01 0.216 0 0
Activation of AKT2 R-HSA-165158 6.083632e-01 0.216 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 5.963685e-01 0.224 0 0
Regulation of necroptotic cell death R-HSA-5675482 5.977468e-01 0.223 0 0
Activation of ATR in response to replication stress R-HSA-176187 5.977468e-01 0.223 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 5.092244e-01 0.293 0 0
Signaling by VEGF R-HSA-194138 2.540070e-01 0.595 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.695615e-01 0.771 0 0
Signaling by WNT R-HSA-195721 4.335999e-01 0.363 0 0
Cell Cycle Checkpoints R-HSA-69620 1.162958e-01 0.934 0 0
Negative regulation of MAPK pathway R-HSA-5675221 2.154024e-01 0.667 0 0
Membrane Trafficking R-HSA-199991 2.579644e-01 0.588 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 1.024721e-01 0.989 0 0
Kinesins R-HSA-983189 7.879741e-02 1.103 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.026261e-01 0.989 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 6.198042e-01 0.208 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 2.012567e-01 0.696 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 8.327751e-02 1.079 0 0
Signaling by FGFR in disease R-HSA-1226099 3.087030e-01 0.510 0 0
Gastrulation R-HSA-9758941 5.591183e-01 0.252 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.026261e-01 0.989 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.026261e-01 0.989 0 0
Interleukin-2 signaling R-HSA-9020558 5.590509e-01 0.253 0 0
Chaperone Mediated Autophagy R-HSA-9613829 5.945354e-01 0.226 0 0
mTORC1-mediated signalling R-HSA-166208 3.221903e-01 0.492 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 2.483036e-01 0.605 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 4.329578e-01 0.364 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 4.772897e-01 0.321 0 0
Ub-specific processing proteases R-HSA-5689880 3.505140e-01 0.455 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 6.312626e-01 0.200 0 0
Deubiquitination R-HSA-5688426 2.150690e-01 0.667 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.791762e-01 0.747 0 0
Programmed Cell Death R-HSA-5357801 1.615090e-01 0.792 0 0
Cell junction organization R-HSA-446728 2.274457e-01 0.643 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.534883e-01 0.596 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.227539e-01 0.652 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 4.244400e-01 0.372 0 0
Cell-cell junction organization R-HSA-421270 4.747996e-01 0.323 0 0
Signaling by TGFBR3 R-HSA-9839373 1.152816e-01 0.938 0 0
Cell Cycle, Mitotic R-HSA-69278 3.216222e-01 0.493 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.146424e-01 0.941 0 0
Polo-like kinase mediated events R-HSA-156711 9.199091e-02 1.036 0 0
FGFR1 mutant receptor activation R-HSA-1839124 1.572775e-01 0.803 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 5.522312e-01 0.258 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 4.674724e-01 0.330 0 0
Eukaryotic Translation Termination R-HSA-72764 3.495011e-01 0.457 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 5.590509e-01 0.253 0 0
HDACs deacetylate histones R-HSA-3214815 6.063045e-01 0.217 0 0
Interleukin-1 family signaling R-HSA-446652 2.742120e-01 0.562 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.068370e-01 0.684 0 0
Developmental Biology R-HSA-1266738 5.227102e-01 0.282 0 0
Signaling by SCF-KIT R-HSA-1433557 5.246039e-01 0.280 0 0
Ion homeostasis R-HSA-5578775 4.864958e-01 0.313 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.162753e-01 0.665 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 4.021555e-01 0.396 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 2.033453e-01 0.692 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 2.418500e-01 0.616 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 1.442975e-01 0.841 0 0
ERK/MAPK targets R-HSA-198753 1.397364e-01 0.855 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 6.205185e-01 0.207 0 0
Repression of WNT target genes R-HSA-4641265 6.312626e-01 0.200 0 0
Cell-Cell communication R-HSA-1500931 2.441191e-01 0.612 0 0
Calmodulin induced events R-HSA-111933 5.147438e-01 0.288 0 0
Signalling to ERKs R-HSA-187687 4.922261e-01 0.308 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.075049e-01 0.683 0 0
GPVI-mediated activation cascade R-HSA-114604 3.547091e-01 0.450 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.673343e-01 0.776 0 0
Apoptosis R-HSA-109581 1.817611e-01 0.740 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 2.216577e-01 0.654 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.334446e-01 0.273 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.504590e-01 0.823 0 0
Cellular response to heat stress R-HSA-3371556 4.447934e-01 0.352 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.504590e-01 0.823 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 3.552843e-01 0.449 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 4.641899e-01 0.333 0 0
CaM pathway R-HSA-111997 5.147438e-01 0.288 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 5.699590e-01 0.244 1 0
G2/M Checkpoints R-HSA-69481 6.234526e-01 0.205 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 4.978515e-01 0.303 0 0
DAG and IP3 signaling R-HSA-1489509 5.647685e-01 0.248 0 0
Cellular Senescence R-HSA-2559583 9.411458e-02 1.026 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 2.851193e-01 0.545 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.130738e-01 0.947 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 5.135249e-01 0.289 0 0
Rab regulation of trafficking R-HSA-9007101 4.879721e-01 0.312 0 0
Toll-like Receptor Cascades R-HSA-168898 4.587797e-01 0.338 0 0
Transport of connexins along the secretory pathway R-HSA-190827 3.308197e-01 0.480 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 8.087665e-02 1.092 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.843045e-01 0.734 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 1.843045e-01 0.734 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 2.183253e-01 0.661 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.146931e-01 0.382 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.957341e-01 0.708 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 1.024721e-01 0.989 0 0
Bicarbonate transporters R-HSA-425381 2.893677e-01 0.539 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.517842e-01 0.599 0 0
Protein hydroxylation R-HSA-9629569 2.459610e-01 0.609 0 0
STAT6-mediated induction of chemokines R-HSA-3249367 4.880582e-01 0.312 0 0
MET interacts with TNS proteins R-HSA-8875513 4.880582e-01 0.312 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 4.880582e-01 0.312 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 4.880582e-01 0.312 0 0
Disorders of Developmental Biology R-HSA-9675151 3.106282e-01 0.508 0 0
Signaling by LTK R-HSA-9842663 3.617720e-01 0.442 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.963662e-01 0.528 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.409599e-01 0.618 0 0
L1CAM interactions R-HSA-373760 1.129597e-01 0.947 0 0
Neurodegenerative Diseases R-HSA-8863678 3.744175e-01 0.427 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.744175e-01 0.427 0 0
Unwinding of DNA R-HSA-176974 4.772897e-01 0.321 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 5.522312e-01 0.258 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.228348e-01 0.491 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 5.193319e-01 0.285 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 5.193319e-01 0.285 0 0
MAPK family signaling cascades R-HSA-5683057 2.167008e-01 0.664 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 4.406772e-01 0.356 0 0
Diseases of Immune System R-HSA-5260271 4.406772e-01 0.356 0 0
Ionotropic activity of kainate receptors R-HSA-451306 5.590509e-01 0.253 0 0
Trafficking of myristoylated proteins to the cilium R-HSA-5624138 6.083632e-01 0.216 0 0
Reelin signalling pathway R-HSA-8866376 6.083632e-01 0.216 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 5.228637e-01 0.282 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.407221e-01 0.267 0 0
Signaling by AMER1 mutants R-HSA-4839748 5.963685e-01 0.224 0 0
Signaling by AXIN mutants R-HSA-4839735 5.963685e-01 0.224 0 0
Apoptotic factor-mediated response R-HSA-111471 5.945354e-01 0.226 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 3.328565e-01 0.478 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.851193e-01 0.545 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.284016e-01 0.368 0 0
FLT3 Signaling R-HSA-9607240 1.995097e-01 0.700 0 0
HIV Life Cycle R-HSA-162587 5.636670e-01 0.249 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 3.387736e-01 0.470 0 0
FLT3 signaling in disease R-HSA-9682385 2.231026e-01 0.651 1 0
G2/M Transition R-HSA-69275 4.834512e-01 0.316 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.452048e-01 0.351 0 0
MAP kinase activation R-HSA-450294 8.604320e-02 1.065 0 0
Signaling by FGFR4 in disease R-HSA-5655291 4.329578e-01 0.364 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.838431e-01 0.736 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.687181e-01 0.773 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.656794e-01 0.576 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 4.524055e-01 0.344 0 0
Reproduction R-HSA-1474165 4.893935e-01 0.310 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.585564e-01 0.800 0 0
Macroautophagy R-HSA-1632852 6.292508e-01 0.201 0 0
Protein methylation R-HSA-8876725 2.517842e-01 0.599 0 0
NOD1/2 Signaling Pathway R-HSA-168638 3.121989e-01 0.506 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 4.229138e-01 0.374 0 0
Interleukin-2 family signaling R-HSA-451927 4.406772e-01 0.356 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 5.955804e-01 0.225 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 7.966169e-02 1.099 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 7.434997e-02 1.129 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 3.391973e-01 0.470 0 0
Interleukin-17 signaling R-HSA-448424 1.694417e-01 0.771 0 0
TBC/RABGAPs R-HSA-8854214 2.485760e-01 0.605 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 5.334446e-01 0.273 1 1
Formation of the nephric duct R-HSA-9830364 5.955804e-01 0.225 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 3.705694e-01 0.431 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 4.661767e-01 0.331 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 6.093314e-01 0.215 0 0
Signaling by PTK6 R-HSA-8848021 6.093314e-01 0.215 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 5.246039e-01 0.280 0 0
Interleukin-1 processing R-HSA-448706 7.966169e-02 1.099 0 0
Heme signaling R-HSA-9707616 9.369721e-02 1.028 0 0
CHL1 interactions R-HSA-447041 3.869254e-01 0.412 0 0
Pervasive developmental disorders R-HSA-9005895 3.617720e-01 0.442 0 0
Disorders of Nervous System Development R-HSA-9697154 3.617720e-01 0.442 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 3.617720e-01 0.442 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 3.976517e-01 0.400 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 6.198042e-01 0.208 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 9.471078e-02 1.024 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.790510e-01 0.747 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 4.922261e-01 0.308 0 0
Amine ligand-binding receptors R-HSA-375280 2.657736e-01 0.575 0 0
Regulation of KIT signaling R-HSA-1433559 4.329578e-01 0.364 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.981414e-01 0.703 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 3.106282e-01 0.508 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 5.161331e-01 0.287 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 6.243338e-01 0.205 0 0
Uptake and function of anthrax toxins R-HSA-5210891 5.646455e-01 0.248 0 0
Glycolysis R-HSA-70171 6.240548e-01 0.205 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 9.693020e-02 1.014 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 1.452373e-01 0.838 0 0
Oligomerization of connexins into connexons R-HSA-190704 3.308197e-01 0.480 0 0
Breakdown of the nuclear lamina R-HSA-352238 3.308197e-01 0.480 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 9.199091e-02 1.036 0 0
DSCAM interactions R-HSA-376172 4.146931e-01 0.382 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 2.809672e-01 0.551 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 4.880582e-01 0.312 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 3.405600e-01 0.468 0 0
Sensory perception of sour taste R-HSA-9729555 5.522312e-01 0.258 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 5.522312e-01 0.258 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 4.593656e-01 0.338 0 0
Synthesis of PI R-HSA-1483226 5.590509e-01 0.253 0 0
PTK6 Down-Regulation R-HSA-8849472 6.083632e-01 0.216 0 0
Biosynthesis of DPAn-3-derived 13-series resolvins R-HSA-9026403 6.083632e-01 0.216 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 5.842580e-01 0.233 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 5.977468e-01 0.223 0 0
PI Metabolism R-HSA-1483255 4.452048e-01 0.351 0 0
Diseases of DNA repair R-HSA-9675135 3.011706e-01 0.521 0 0
Stimuli-sensing channels R-HSA-2672351 4.406666e-01 0.356 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 2.606328e-01 0.584 0 0
Nephrin family interactions R-HSA-373753 4.301253e-01 0.366 0 0
Cytokine Signaling in Immune system R-HSA-1280215 4.647004e-01 0.333 1 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 5.434551e-01 0.265 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 3.994504e-01 0.399 0 0
SARS-CoV-1-host interactions R-HSA-9692914 2.405103e-01 0.619 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 1.767942e-01 0.753 0 0
Histamine receptors R-HSA-390650 4.880582e-01 0.312 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 4.674724e-01 0.330 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.340146e-01 0.476 0 0
Selenocysteine synthesis R-HSA-2408557 4.314440e-01 0.365 0 0
PECAM1 interactions R-HSA-210990 5.590509e-01 0.253 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 5.646455e-01 0.248 0 0
Signaling by ALK in cancer R-HSA-9700206 3.340146e-01 0.476 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 5.977468e-01 0.223 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 1.452373e-01 0.838 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 2.903843e-01 0.537 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 4.146931e-01 0.382 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 4.146931e-01 0.382 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.869254e-01 0.412 0 0
Interleukin-18 signaling R-HSA-9012546 4.330741e-01 0.363 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 5.522312e-01 0.258 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 6.083632e-01 0.216 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 4.726655e-01 0.325 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 5.963685e-01 0.224 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 6.236567e-01 0.205 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.596476e-01 0.797 1 1
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 4.121073e-01 0.385 0 0
Interleukin-7 signaling R-HSA-1266695 4.005728e-01 0.397 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 6.312626e-01 0.200 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.411551e-01 0.618 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 4.146931e-01 0.382 0 0
FasL/ CD95L signaling R-HSA-75157 4.880582e-01 0.312 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 5.963685e-01 0.224 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 6.256605e-01 0.204 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 3.705694e-01 0.431 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 4.593656e-01 0.338 0 0
Nephron development R-HSA-9831926 5.945354e-01 0.226 0 0
Interleukin-15 signaling R-HSA-8983432 6.312626e-01 0.200 0 0
SARS-CoV-1 Infection R-HSA-9678108 3.006113e-01 0.522 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 6.083632e-01 0.216 0 0
OAS antiviral response R-HSA-8983711 6.312626e-01 0.200 0 0
IRE1alpha activates chaperones R-HSA-381070 5.935458e-01 0.227 0 0
Response to metal ions R-HSA-5660526 5.334446e-01 0.273 0 0
XBP1(S) activates chaperone genes R-HSA-381038 6.182954e-01 0.209 0 0
Signaling by Leptin R-HSA-2586552 5.193319e-01 0.285 0 0
Interleukin-12 family signaling R-HSA-447115 1.534845e-01 0.814 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 6.312626e-01 0.200 0 0
Interleukin-37 signaling R-HSA-9008059 1.150210e-01 0.939 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 1.981414e-01 0.703 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 3.221903e-01 0.492 0 0
Separation of Sister Chromatids R-HSA-2467813 6.374490e-01 0.196 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 6.399852e-01 0.194 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 6.399852e-01 0.194 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 6.399852e-01 0.194 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 6.400356e-01 0.194 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 6.400641e-01 0.194 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 6.411265e-01 0.193 0 0
Nuclear import of Rev protein R-HSA-180746 6.411265e-01 0.193 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 6.439861e-01 0.191 0 0
Signaling by FGFR3 in disease R-HSA-5655332 6.439861e-01 0.191 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 6.439861e-01 0.191 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 6.439861e-01 0.191 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.444720e-01 0.191 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 6.501712e-01 0.187 0 0
Negative regulation of MET activity R-HSA-6807004 6.501712e-01 0.187 0 0
Creatine metabolism R-HSA-71288 6.501712e-01 0.187 0 0
Signal transduction by L1 R-HSA-445144 6.501712e-01 0.187 0 0
Adherens junctions interactions R-HSA-418990 6.547219e-01 0.184 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 6.570816e-01 0.182 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 6.570816e-01 0.182 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 6.574614e-01 0.182 0 0
PDE3B signalling R-HSA-165160 6.574614e-01 0.182 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 6.574614e-01 0.182 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 6.574614e-01 0.182 0 0
PKB-mediated events R-HSA-109703 6.574614e-01 0.182 0 0
Defective CSF2RB causes SMDP5 R-HSA-5688849 6.574614e-01 0.182 0 0
Defective CSF2RA causes SMDP4 R-HSA-5688890 6.574614e-01 0.182 0 0
NGF-independant TRKA activation R-HSA-187024 6.574614e-01 0.182 0 0
Pentose phosphate pathway disease R-HSA-6791465 6.574614e-01 0.182 0 0
Synthesis of PS R-HSA-1483101 6.574614e-01 0.182 0 0
Ceramide signalling R-HSA-193681 6.574614e-01 0.182 0 0
Phosphorylation of Emi1 R-HSA-176417 6.574614e-01 0.182 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 6.574614e-01 0.182 0 0
Formation of the Editosome R-HSA-75094 6.574614e-01 0.182 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 6.574614e-01 0.182 0 0
Release of Hh-Np from the secreting cell R-HSA-5362798 6.574614e-01 0.182 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 6.574614e-01 0.182 0 0
Acetylcholine inhibits contraction of outer hair cells R-HSA-9667769 6.574614e-01 0.182 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 6.574614e-01 0.182 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 6.574614e-01 0.182 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 6.574614e-01 0.182 0 0
TRAIL signaling R-HSA-75158 6.574614e-01 0.182 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 6.589406e-01 0.181 0 0
Ca-dependent events R-HSA-111996 6.589406e-01 0.181 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 6.589406e-01 0.181 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 6.616879e-01 0.179 0 0
CD28 dependent Vav1 pathway R-HSA-389359 6.637542e-01 0.178 0 0
FGFR1c ligand binding and activation R-HSA-190373 6.637542e-01 0.178 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 6.637542e-01 0.178 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 6.637542e-01 0.178 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 6.637542e-01 0.178 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 6.637542e-01 0.178 0 0
HIV Infection R-HSA-162906 6.655131e-01 0.177 0 0
Telomere Extension By Telomerase R-HSA-171319 6.667055e-01 0.176 0 0
Organelle biogenesis and maintenance R-HSA-1852241 6.676656e-01 0.175 0 0
Kidney development R-HSA-9830369 6.723780e-01 0.172 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.746210e-01 0.171 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 6.758643e-01 0.170 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.758643e-01 0.170 0 0
Mitochondrial biogenesis R-HSA-1592230 6.766645e-01 0.170 0 0
Ribosome-associated quality control R-HSA-9948299 6.805463e-01 0.167 0 0
Signaling by NOTCH1 R-HSA-1980143 6.862498e-01 0.164 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 6.884108e-01 0.162 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 6.884108e-01 0.162 0 0
Platelet calcium homeostasis R-HSA-418360 6.884108e-01 0.162 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 6.886956e-01 0.162 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 6.886956e-01 0.162 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 6.886956e-01 0.162 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 6.886956e-01 0.162 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 6.886956e-01 0.162 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 6.886956e-01 0.162 0 0
PTEN Regulation R-HSA-6807070 6.908417e-01 0.161 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 6.938974e-01 0.159 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 6.938974e-01 0.159 0 0
Retrograde neurotrophin signalling R-HSA-177504 6.938974e-01 0.159 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 6.938974e-01 0.159 0 0
cGMP effects R-HSA-418457 6.938974e-01 0.159 0 0
Non-canonical inflammasome activation R-HSA-9686114 6.938974e-01 0.159 0 0
Cyclin D associated events in G1 R-HSA-69231 6.948452e-01 0.158 0 0
G1 Phase R-HSA-69236 6.948452e-01 0.158 0 0
DAP12 interactions R-HSA-2172127 6.948452e-01 0.158 0 0
RMTs methylate histone arginines R-HSA-3214858 6.948452e-01 0.158 0 0
Signaling by FGFR R-HSA-190236 6.981684e-01 0.156 0 0
Meiosis R-HSA-1500620 6.989589e-01 0.156 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 7.001347e-01 0.155 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 7.001347e-01 0.155 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 7.001347e-01 0.155 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 7.001347e-01 0.155 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 7.004068e-01 0.155 0 0
STAT5 Activation R-HSA-9645135 7.004068e-01 0.155 0 0
Erythropoietin activates STAT5 R-HSA-9027283 7.004068e-01 0.155 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 7.004068e-01 0.155 0 0
Neurofascin interactions R-HSA-447043 7.004068e-01 0.155 0 0
Abacavir transmembrane transport R-HSA-2161517 7.004068e-01 0.155 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 7.004068e-01 0.155 0 0
NADPH regeneration R-HSA-389542 7.004068e-01 0.155 0 0
Nef and signal transduction R-HSA-164944 7.004068e-01 0.155 0 0
Lipid particle organization R-HSA-8964572 7.004068e-01 0.155 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 7.004580e-01 0.155 0 0
PLC beta mediated events R-HSA-112043 7.037943e-01 0.153 0 0
rRNA processing R-HSA-72312 7.063642e-01 0.151 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.090948e-01 0.149 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 7.090948e-01 0.149 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.117425e-01 0.148 0 0
Autophagy R-HSA-9612973 7.121891e-01 0.147 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 7.154310e-01 0.145 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 7.154310e-01 0.145 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 7.154310e-01 0.145 0 0
MET promotes cell motility R-HSA-8875878 7.186472e-01 0.143 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 7.186472e-01 0.143 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 7.186472e-01 0.143 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 7.186472e-01 0.143 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 7.217702e-01 0.142 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 7.217702e-01 0.142 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.217702e-01 0.142 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 7.217702e-01 0.142 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 7.217702e-01 0.142 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 7.217702e-01 0.142 0 0
DNA Damage Reversal R-HSA-73942 7.217702e-01 0.142 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 7.224996e-01 0.141 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 7.226787e-01 0.141 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 7.229959e-01 0.141 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 7.229959e-01 0.141 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 7.229959e-01 0.141 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 7.229959e-01 0.141 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 7.229959e-01 0.141 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 7.229959e-01 0.141 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 7.229959e-01 0.141 0 0
Budding and maturation of HIV virion R-HSA-162588 7.287586e-01 0.137 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 7.287586e-01 0.137 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 7.289286e-01 0.137 0 0
Hedgehog 'on' state R-HSA-5632684 7.289286e-01 0.137 0 0
Signaling by ALK R-HSA-201556 7.360352e-01 0.133 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 7.360352e-01 0.133 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 7.379701e-01 0.132 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 7.379701e-01 0.132 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 7.379701e-01 0.132 0 0
Netrin mediated repulsion signals R-HSA-418886 7.379701e-01 0.132 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 7.379701e-01 0.132 0 0
IFNG signaling activates MAPKs R-HSA-9732724 7.379701e-01 0.132 0 0
DAG1 core M1 glycosylations R-HSA-8932506 7.379701e-01 0.132 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 7.379701e-01 0.132 0 0
mRNA Editing: C to U Conversion R-HSA-72200 7.379701e-01 0.132 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 7.379701e-01 0.132 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 7.379701e-01 0.132 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 7.379701e-01 0.132 0 0
VLDL clearance R-HSA-8964046 7.379701e-01 0.132 0 0
Activation of TRKA receptors R-HSA-187015 7.379701e-01 0.132 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 7.379701e-01 0.132 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 7.379701e-01 0.132 0 0
Glycoprotein hormones R-HSA-209822 7.379701e-01 0.132 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 7.379701e-01 0.132 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 7.387601e-01 0.131 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 7.437953e-01 0.129 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 7.438576e-01 0.129 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 7.444724e-01 0.128 0 0
Syndecan interactions R-HSA-3000170 7.444724e-01 0.128 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.444724e-01 0.128 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 7.456767e-01 0.127 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 7.474679e-01 0.126 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 7.474679e-01 0.126 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 7.474679e-01 0.126 0 0
Killing mechanisms R-HSA-9664420 7.474679e-01 0.126 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 7.474679e-01 0.126 0 0
Attachment and Entry R-HSA-9678110 7.474679e-01 0.126 0 0
Phase 4 - resting membrane potential R-HSA-5576886 7.474679e-01 0.126 0 0
Regulation of BACH1 activity R-HSA-9708530 7.474679e-01 0.126 0 0
Negative regulation of FLT3 R-HSA-9706369 7.474679e-01 0.126 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 7.474679e-01 0.126 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 7.474679e-01 0.126 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 7.526250e-01 0.123 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 7.526250e-01 0.123 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 7.526250e-01 0.123 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 7.526250e-01 0.123 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 7.526250e-01 0.123 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 7.526250e-01 0.123 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 7.526250e-01 0.123 0 0
Signaling by Hedgehog R-HSA-5358351 7.580409e-01 0.120 0 0
Adipogenesis R-HSA-9843745 7.588716e-01 0.120 0 0
Glucose metabolism R-HSA-70326 7.612550e-01 0.118 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 7.650637e-01 0.116 0 0
Signaling by ERBB4 R-HSA-1236394 7.668081e-01 0.115 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 7.684239e-01 0.114 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 7.684239e-01 0.114 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 7.692494e-01 0.114 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 7.692494e-01 0.114 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 7.692494e-01 0.114 0 0
Downstream TCR signaling R-HSA-202424 7.703744e-01 0.113 0 0
DAG1 core M2 glycosylations R-HSA-8932504 7.708257e-01 0.113 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 7.708257e-01 0.113 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 7.708257e-01 0.113 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 7.708257e-01 0.113 0 0
MET receptor recycling R-HSA-8875656 7.708257e-01 0.113 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 7.708257e-01 0.113 0 0
Co-stimulation by ICOS R-HSA-9927354 7.708257e-01 0.113 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 7.708257e-01 0.113 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 7.708257e-01 0.113 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 7.708257e-01 0.113 0 0
Alpha-defensins R-HSA-1462054 7.708257e-01 0.113 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 7.708257e-01 0.113 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 7.710977e-01 0.113 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 7.710977e-01 0.113 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 7.710977e-01 0.113 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 7.710977e-01 0.113 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 7.710977e-01 0.113 0 0
Synthesis of PG R-HSA-1483148 7.710977e-01 0.113 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 7.719714e-01 0.112 0 0
Inositol phosphate metabolism R-HSA-1483249 7.726982e-01 0.112 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.767121e-01 0.110 0 0
Influenza Infection R-HSA-168255 7.798419e-01 0.108 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.834151e-01 0.106 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 7.834151e-01 0.106 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 7.834151e-01 0.106 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 7.834428e-01 0.106 0 0
HIV Transcription Initiation R-HSA-167161 7.834428e-01 0.106 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 7.834428e-01 0.106 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 7.834428e-01 0.106 0 0
Intra-Golgi traffic R-HSA-6811438 7.834428e-01 0.106 0 0
G-protein mediated events R-HSA-112040 7.841354e-01 0.106 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.850276e-01 0.105 0 0
Regulation of RAS by GAPs R-HSA-5658442 7.868255e-01 0.104 0 0
Signaling by FGFR2 in disease R-HSA-5655253 7.868255e-01 0.104 0 0
Muscle contraction R-HSA-397014 7.926201e-01 0.101 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 7.927741e-01 0.101 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 7.927741e-01 0.101 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 7.927741e-01 0.101 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 7.927741e-01 0.101 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 7.927741e-01 0.101 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 7.958145e-01 0.099 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 7.974593e-01 0.098 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 7.974593e-01 0.098 0 0
Potential therapeutics for SARS R-HSA-9679191 7.987758e-01 0.098 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 7.995632e-01 0.097 0 0
Interleukin-21 signaling R-HSA-9020958 7.995632e-01 0.097 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 7.995632e-01 0.097 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 7.995632e-01 0.097 0 0
ARMS-mediated activation R-HSA-170984 7.995632e-01 0.097 0 0
Regulation of signaling by NODAL R-HSA-1433617 7.995632e-01 0.097 0 0
mRNA Editing R-HSA-75072 7.995632e-01 0.097 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 7.995632e-01 0.097 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 7.995632e-01 0.097 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 7.995632e-01 0.097 0 0
HSF1-dependent transactivation R-HSA-3371571 7.998794e-01 0.097 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 8.009700e-01 0.096 0 0
Metalloprotease DUBs R-HSA-5689901 8.009700e-01 0.096 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 8.009700e-01 0.096 0 0
Signaling by Insulin receptor R-HSA-74752 8.012739e-01 0.096 0 0
Integration of energy metabolism R-HSA-163685 8.099632e-01 0.092 0 0
Developmental Cell Lineages R-HSA-9734767 8.100942e-01 0.091 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.112000e-01 0.091 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 8.122525e-01 0.090 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 8.122525e-01 0.090 0 0
Oncogene Induced Senescence R-HSA-2559585 8.122525e-01 0.090 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 8.126154e-01 0.090 0 0
FGFR1 ligand binding and activation R-HSA-190242 8.126154e-01 0.090 0 0
Mismatch Repair R-HSA-5358508 8.126154e-01 0.090 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 8.126154e-01 0.090 0 0
Tie2 Signaling R-HSA-210993 8.126154e-01 0.090 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 8.146538e-01 0.089 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.158724e-01 0.088 0 0
DNA Repair R-HSA-73894 8.162620e-01 0.088 0 0
Cristae formation R-HSA-8949613 8.173143e-01 0.088 0 0
Sensory processing of sound R-HSA-9659379 8.212743e-01 0.086 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 8.241186e-01 0.084 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 8.241186e-01 0.084 0 0
Smooth Muscle Contraction R-HSA-445355 8.241186e-01 0.084 0 0
MAPK3 (ERK1) activation R-HSA-110056 8.246985e-01 0.084 0 0
2-LTR circle formation R-HSA-164843 8.246985e-01 0.084 0 0
Folding of actin by CCT/TriC R-HSA-390450 8.246985e-01 0.084 0 0
TET1,2,3 and TDG demethylate DNA R-HSA-5221030 8.246985e-01 0.084 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 8.246985e-01 0.084 0 0
Formation of intermediate mesoderm R-HSA-9761174 8.246985e-01 0.084 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 8.246985e-01 0.084 0 0
Receptor Mediated Mitophagy R-HSA-8934903 8.246985e-01 0.084 0 0
Maturation of spike protein R-HSA-9683686 8.246985e-01 0.084 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 8.246985e-01 0.084 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 8.246985e-01 0.084 0 0
Peptide hormone biosynthesis R-HSA-209952 8.246985e-01 0.084 0 0
Regulation of the apoptosome activity R-HSA-9627069 8.246985e-01 0.084 0 0
Josephin domain DUBs R-HSA-5689877 8.246985e-01 0.084 0 0
Tandem pore domain potassium channels R-HSA-1296346 8.246985e-01 0.084 0 0
Formation of apoptosome R-HSA-111458 8.246985e-01 0.084 0 0
NCAM signaling for neurite out-growth R-HSA-375165 8.256376e-01 0.083 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 8.307408e-01 0.081 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 8.307408e-01 0.081 0 0
Other interleukin signaling R-HSA-449836 8.307408e-01 0.081 0 0
The NLRP3 inflammasome R-HSA-844456 8.307408e-01 0.081 0 0
Signaling by MET R-HSA-6806834 8.309025e-01 0.080 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 8.325028e-01 0.080 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 8.325028e-01 0.080 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.325028e-01 0.080 0 0
Cellular responses to stimuli R-HSA-8953897 8.325893e-01 0.080 0 0
Selective autophagy R-HSA-9663891 8.341356e-01 0.079 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 8.360398e-01 0.078 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.360398e-01 0.078 0 0
Nucleosome assembly R-HSA-774815 8.360398e-01 0.078 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 8.360398e-01 0.078 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 8.360398e-01 0.078 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 8.360398e-01 0.078 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 8.391808e-01 0.076 0 0
SARS-CoV-2-host interactions R-HSA-9705683 8.410311e-01 0.075 0 0
Opioid Signalling R-HSA-111885 8.411314e-01 0.075 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 8.430056e-01 0.074 0 0
S Phase R-HSA-69242 8.437517e-01 0.074 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 8.459627e-01 0.073 0 0
Signaling by NOTCH3 R-HSA-9012852 8.459627e-01 0.073 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 8.465917e-01 0.072 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 8.466832e-01 0.072 0 0
DAG1 core M3 glycosylations R-HSA-8932505 8.466832e-01 0.072 0 0
LGI-ADAM interactions R-HSA-5682910 8.466832e-01 0.072 0 0
FGFR2b ligand binding and activation R-HSA-190377 8.466832e-01 0.072 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 8.466832e-01 0.072 0 0
FGFRL1 modulation of FGFR1 signaling R-HSA-5658623 8.466832e-01 0.072 0 0
Transport of RCbl within the body R-HSA-9758890 8.466832e-01 0.072 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 8.466832e-01 0.072 0 0
Biosynthesis of DPAn-3-derived maresins R-HSA-9026290 8.466832e-01 0.072 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 8.466832e-01 0.072 0 0
Suppression of apoptosis R-HSA-9635465 8.466832e-01 0.072 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 8.471710e-01 0.072 0 0
Ca2+ pathway R-HSA-4086398 8.471710e-01 0.072 0 0
Co-inhibition by CTLA4 R-HSA-389513 8.472686e-01 0.072 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 8.472686e-01 0.072 0 0
Signaling by NODAL R-HSA-1181150 8.472686e-01 0.072 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 8.472686e-01 0.072 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 8.474194e-01 0.072 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 8.474194e-01 0.072 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 8.483828e-01 0.071 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.489332e-01 0.071 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.489332e-01 0.071 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 8.489473e-01 0.071 0 0
Cellular response to starvation R-HSA-9711097 8.541949e-01 0.068 0 0
Cellular response to hypoxia R-HSA-1234174 8.555307e-01 0.068 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 8.560278e-01 0.068 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 8.581369e-01 0.066 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 8.596388e-01 0.066 0 0
Interferon gamma signaling R-HSA-877300 8.602203e-01 0.065 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 8.623143e-01 0.064 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 8.623143e-01 0.064 0 0
Signalling to RAS R-HSA-167044 8.623143e-01 0.064 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 8.623143e-01 0.064 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 8.623143e-01 0.064 0 0
Early Phase of HIV Life Cycle R-HSA-162594 8.623143e-01 0.064 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 8.626299e-01 0.064 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.627902e-01 0.064 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 8.645197e-01 0.063 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 8.645969e-01 0.063 0 0
ISG15 antiviral mechanism R-HSA-1169408 8.645969e-01 0.063 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 8.659118e-01 0.063 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 8.659118e-01 0.063 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 8.659118e-01 0.063 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 8.659118e-01 0.063 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 8.659118e-01 0.063 0 0
Anchoring fibril formation R-HSA-2214320 8.659118e-01 0.063 0 0
Sodium/Calcium exchangers R-HSA-425561 8.659118e-01 0.063 0 0
Integration of provirus R-HSA-162592 8.659118e-01 0.063 0 0
Intraflagellar transport R-HSA-5620924 8.682171e-01 0.061 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 8.682296e-01 0.061 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 8.717016e-01 0.060 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 8.717016e-01 0.060 0 0
UCH proteinases R-HSA-5689603 8.726852e-01 0.059 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 8.734392e-01 0.059 0 0
Glycogen metabolism R-HSA-8982491 8.734392e-01 0.059 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 8.750892e-01 0.058 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 8.759897e-01 0.058 0 0
Attachment and Entry R-HSA-9694614 8.759897e-01 0.058 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 8.759897e-01 0.058 0 0
Degradation of CDH1 R-HSA-9766229 8.776857e-01 0.057 0 0
Host Interactions of HIV factors R-HSA-162909 8.811468e-01 0.055 0 0
Scavenging by Class F Receptors R-HSA-3000484 8.827298e-01 0.054 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 8.827298e-01 0.054 0 0
MET activates RAS signaling R-HSA-8851805 8.827298e-01 0.054 0 0
VLDLR internalisation and degradation R-HSA-8866427 8.827298e-01 0.054 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 8.827298e-01 0.054 0 0
Biosynthesis of DPAn-3-derived protectins and resolvins R-HSA-9026286 8.827298e-01 0.054 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 8.827298e-01 0.054 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 8.827298e-01 0.054 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 8.827298e-01 0.054 0 0
Estrogen biosynthesis R-HSA-193144 8.827298e-01 0.054 0 0
Inwardly rectifying K+ channels R-HSA-1296065 8.828377e-01 0.054 0 0
Signaling by WNT in cancer R-HSA-4791275 8.828377e-01 0.054 0 0
DNA strand elongation R-HSA-69190 8.828377e-01 0.054 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.833665e-01 0.054 0 0
Cellular responses to stress R-HSA-2262752 8.847278e-01 0.053 0 0
PCP/CE pathway R-HSA-4086400 8.876737e-01 0.052 0 0
Integrin cell surface interactions R-HSA-216083 8.876737e-01 0.052 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 8.884017e-01 0.051 0 0
Signaling by KIT in disease R-HSA-9669938 8.884017e-01 0.051 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 8.884017e-01 0.051 0 0
LDL clearance R-HSA-8964038 8.884017e-01 0.051 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.926085e-01 0.049 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.926085e-01 0.049 0 0
Adaptive Immune System R-HSA-1280218 8.944696e-01 0.048 0 0
Adenylate cyclase activating pathway R-HSA-170660 8.974392e-01 0.047 0 0
FGFR2c ligand binding and activation R-HSA-190375 8.974392e-01 0.047 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 8.974392e-01 0.047 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 8.974392e-01 0.047 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 8.974392e-01 0.047 0 0
FGFR4 ligand binding and activation R-HSA-190322 8.974392e-01 0.047 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 8.974392e-01 0.047 0 0
Chylomicron remodeling R-HSA-8963901 8.974392e-01 0.047 0 0
Mtb iron assimilation by chelation R-HSA-1222449 8.974392e-01 0.047 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 8.974392e-01 0.047 0 0
FGFR3 mutant receptor activation R-HSA-2033514 8.974392e-01 0.047 0 0
rRNA modification in the mitochondrion R-HSA-6793080 8.974392e-01 0.047 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 8.974392e-01 0.047 0 0
Maturation of nucleoprotein R-HSA-9683610 8.974392e-01 0.047 0 0
Interleukin-6 signaling R-HSA-1059683 8.974392e-01 0.047 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.974392e-01 0.047 0 0
Viral Messenger RNA Synthesis R-HSA-168325 8.985274e-01 0.046 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 8.996521e-01 0.046 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 8.996521e-01 0.046 0 0
Formation of the ureteric bud R-HSA-9830674 8.996521e-01 0.046 0 0
Carnitine shuttle R-HSA-200425 8.996521e-01 0.046 0 0
Growth hormone receptor signaling R-HSA-982772 8.996521e-01 0.046 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.002869e-01 0.046 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 9.025543e-01 0.045 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 9.025543e-01 0.045 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.025543e-01 0.045 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 9.025543e-01 0.045 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.026809e-01 0.044 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 9.028144e-01 0.044 0 0
Regulation of mitotic cell cycle R-HSA-453276 9.028144e-01 0.044 0 0
tRNA processing in the nucleus R-HSA-6784531 9.055994e-01 0.043 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 9.057335e-01 0.043 0 0
COPI-mediated anterograde transport R-HSA-6807878 9.059048e-01 0.043 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 9.098369e-01 0.041 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.098369e-01 0.041 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 9.098369e-01 0.041 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.098369e-01 0.041 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 9.103044e-01 0.041 0 0
CRMPs in Sema3A signaling R-HSA-399956 9.103044e-01 0.041 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 9.103044e-01 0.041 0 0
FGFR3c ligand binding and activation R-HSA-190372 9.103044e-01 0.041 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 9.103044e-01 0.041 0 0
Biosynthesis of E-series 18(R)-resolvins R-HSA-9023661 9.103044e-01 0.041 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 9.103044e-01 0.041 0 0
Removal of the Flap Intermediate R-HSA-69166 9.103044e-01 0.041 0 0
Prolactin receptor signaling R-HSA-1170546 9.103044e-01 0.041 0 0
Physiological factors R-HSA-5578768 9.103044e-01 0.041 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 9.103044e-01 0.041 0 0
HDL assembly R-HSA-8963896 9.103044e-01 0.041 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 9.103044e-01 0.041 0 0
Signal regulatory protein family interactions R-HSA-391160 9.103044e-01 0.041 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 9.103044e-01 0.041 0 0
Nucleotide Excision Repair R-HSA-5696398 9.112334e-01 0.040 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 9.112434e-01 0.040 0 0
Signaling by NOTCH2 R-HSA-1980145 9.112434e-01 0.040 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.112434e-01 0.040 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.165826e-01 0.038 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.188158e-01 0.037 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 9.190463e-01 0.037 0 0
G protein gated Potassium channels R-HSA-1296059 9.190463e-01 0.037 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 9.190463e-01 0.037 0 0
Acyl chain remodelling of PS R-HSA-1482801 9.190463e-01 0.037 0 0
Laminin interactions R-HSA-3000157 9.190463e-01 0.037 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 9.190463e-01 0.037 0 0
Hyaluronan degradation R-HSA-2160916 9.190463e-01 0.037 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.209337e-01 0.036 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 9.215564e-01 0.035 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 9.215564e-01 0.035 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 9.215564e-01 0.035 0 0
G beta:gamma signalling through BTK R-HSA-8964315 9.215564e-01 0.035 0 0
Protein lipoylation R-HSA-9857492 9.215564e-01 0.035 0 0
Telomere C-strand synthesis initiation R-HSA-174430 9.215564e-01 0.035 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 9.215564e-01 0.035 0 0
p38MAPK events R-HSA-171007 9.215564e-01 0.035 0 0
Biotin transport and metabolism R-HSA-196780 9.215564e-01 0.035 0 0
FGFR3 ligand binding and activation R-HSA-190239 9.215564e-01 0.035 0 0
Events associated with phagocytolytic activity of PMN cells R-HSA-8941413 9.215564e-01 0.035 0 0
FASTK family proteins regulate processing and stability of mitochondrial RNAs R-HSA-9837092 9.215564e-01 0.035 0 0
Processive synthesis on the lagging strand R-HSA-69183 9.215564e-01 0.035 0 0
Other semaphorin interactions R-HSA-416700 9.215564e-01 0.035 0 0
Vesicle-mediated transport R-HSA-5653656 9.234052e-01 0.035 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.234398e-01 0.035 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.234398e-01 0.035 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.234398e-01 0.035 0 0
Fanconi Anemia Pathway R-HSA-6783310 9.234398e-01 0.035 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.234398e-01 0.035 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 9.240644e-01 0.034 0 0
Cardiac conduction R-HSA-5576891 9.256670e-01 0.034 0 0
Unfolded Protein Response (UPR) R-HSA-381119 9.261426e-01 0.033 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.265410e-01 0.033 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.265410e-01 0.033 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 9.265410e-01 0.033 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.265410e-01 0.033 0 0
Triglyceride catabolism R-HSA-163560 9.265410e-01 0.033 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.265410e-01 0.033 0 0
RUNX2 regulates bone development R-HSA-8941326 9.265410e-01 0.033 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.273648e-01 0.033 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.273648e-01 0.033 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 9.290168e-01 0.032 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 9.297859e-01 0.032 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.297859e-01 0.032 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.297859e-01 0.032 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 9.313975e-01 0.031 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 9.313975e-01 0.031 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 9.313975e-01 0.031 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 9.313975e-01 0.031 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 9.313975e-01 0.031 0 0
Activation of SMO R-HSA-5635838 9.313975e-01 0.031 0 0
Synthesis of wybutosine at G37 of tRNA(Phe) R-HSA-6782861 9.313975e-01 0.031 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 9.313975e-01 0.031 0 0
Atorvastatin ADME R-HSA-9754706 9.313975e-01 0.031 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 9.314698e-01 0.031 0 0
Degradation of DVL R-HSA-4641258 9.332460e-01 0.030 0 0
Regulation of CDH1 Function R-HSA-9764561 9.345168e-01 0.029 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 9.348709e-01 0.029 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 9.348709e-01 0.029 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.348709e-01 0.029 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 9.348709e-01 0.029 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 9.348709e-01 0.029 0 0
Signaling by BMP R-HSA-201451 9.348709e-01 0.029 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 9.396920e-01 0.027 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 9.400045e-01 0.027 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 9.400045e-01 0.027 0 0
Glycine degradation R-HSA-6783984 9.400045e-01 0.027 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.400045e-01 0.027 0 0
Vitamin B6 activation to pyridoxal phosphate R-HSA-964975 9.400045e-01 0.027 0 0
Phase 2 - plateau phase R-HSA-5576893 9.400045e-01 0.027 0 0
Passive transport by Aquaporins R-HSA-432047 9.400045e-01 0.027 0 0
Fibronectin matrix formation R-HSA-1566977 9.400045e-01 0.027 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 9.400045e-01 0.027 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 9.400045e-01 0.027 0 0
Platelet degranulation R-HSA-114608 9.405487e-01 0.027 0 0
RNA Polymerase I Transcription R-HSA-73864 9.406725e-01 0.027 0 0
Metal ion SLC transporters R-HSA-425410 9.410709e-01 0.026 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 9.410709e-01 0.026 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 9.416375e-01 0.026 0 0
Pyrimidine salvage R-HSA-73614 9.416375e-01 0.026 0 0
Inflammasomes R-HSA-622312 9.416375e-01 0.026 0 0
Extension of Telomeres R-HSA-180786 9.443876e-01 0.025 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.443876e-01 0.025 0 0
Stabilization of p53 R-HSA-69541 9.449931e-01 0.025 0 0
Gap junction trafficking and regulation R-HSA-157858 9.460699e-01 0.024 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.460718e-01 0.024 0 0
Diseases of programmed cell death R-HSA-9645723 9.461194e-01 0.024 0 0
SARS-CoV Infections R-HSA-9679506 9.462188e-01 0.024 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 9.475320e-01 0.023 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.475320e-01 0.023 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 9.475320e-01 0.023 0 0
Biosynthesis of aspirin-triggered D-series resolvins R-HSA-9020265 9.475320e-01 0.023 0 0
Sulfide oxidation to sulfate R-HSA-1614517 9.475320e-01 0.023 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 9.475320e-01 0.023 0 0
GDP-fucose biosynthesis R-HSA-6787639 9.475320e-01 0.023 0 0
Choline catabolism R-HSA-6798163 9.475320e-01 0.023 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 9.475320e-01 0.023 0 0
Chromosome Maintenance R-HSA-73886 9.476288e-01 0.023 0 0
mRNA Capping R-HSA-72086 9.477319e-01 0.023 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.477319e-01 0.023 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 9.501177e-01 0.022 0 0
Attenuation phase R-HSA-3371568 9.501177e-01 0.022 0 0
Selenoamino acid metabolism R-HSA-2408522 9.522103e-01 0.021 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 9.522764e-01 0.021 0 0
Activation of the pre-replicative complex R-HSA-68962 9.532162e-01 0.021 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.532162e-01 0.021 0 0
Activation of BH3-only proteins R-HSA-114452 9.532162e-01 0.021 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 9.541155e-01 0.020 0 0
Transport of connexons to the plasma membrane R-HSA-190872 9.541155e-01 0.020 0 0
Activated point mutants of FGFR2 R-HSA-2033519 9.541155e-01 0.020 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 9.541155e-01 0.020 0 0
Presynaptic function of Kainate receptors R-HSA-500657 9.541155e-01 0.020 0 0
Biosynthesis of Lipoxins (LX) R-HSA-2142700 9.541155e-01 0.020 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.541155e-01 0.020 0 0
Platelet sensitization by LDL R-HSA-432142 9.541155e-01 0.020 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 9.541155e-01 0.020 0 0
Regulation of insulin secretion R-HSA-422356 9.543888e-01 0.020 0 0
Maturation of spike protein R-HSA-9694548 9.547940e-01 0.020 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.547940e-01 0.020 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 9.547940e-01 0.020 0 0
Meiotic recombination R-HSA-912446 9.549213e-01 0.020 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.549213e-01 0.020 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 9.564429e-01 0.019 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.566864e-01 0.019 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.571816e-01 0.019 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.581476e-01 0.019 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.581476e-01 0.019 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 9.588257e-01 0.018 0 0
Orc1 removal from chromatin R-HSA-68949 9.588257e-01 0.018 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 9.588257e-01 0.018 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.590576e-01 0.018 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.590576e-01 0.018 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.592120e-01 0.018 0 0
Translesion Synthesis by POLH R-HSA-110320 9.598732e-01 0.018 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 9.598732e-01 0.018 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.598732e-01 0.018 0 0
Diseases of hemostasis R-HSA-9671793 9.598732e-01 0.018 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.598732e-01 0.018 0 0
Crosslinking of collagen fibrils R-HSA-2243919 9.598732e-01 0.018 0 0
Maturation of nucleoprotein R-HSA-9694631 9.598732e-01 0.018 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 9.598732e-01 0.018 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.607467e-01 0.017 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.618108e-01 0.017 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.625784e-01 0.017 0 0
GABA B receptor activation R-HSA-977444 9.629413e-01 0.016 0 0
Activation of GABAB receptors R-HSA-991365 9.629413e-01 0.016 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 9.649087e-01 0.016 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.649087e-01 0.016 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 9.649087e-01 0.016 0 0
Protein ubiquitination R-HSA-8852135 9.652621e-01 0.015 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.664763e-01 0.015 0 0
Defective B3GALTL causes PpS R-HSA-5083635 9.665566e-01 0.015 0 0
Collagen formation R-HSA-1474290 9.674431e-01 0.014 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.674460e-01 0.014 0 0
Ion channel transport R-HSA-983712 9.689339e-01 0.014 0 0
FGFR2 ligand binding and activation R-HSA-190241 9.693126e-01 0.014 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 9.693126e-01 0.014 0 0
G-protein activation R-HSA-202040 9.693126e-01 0.014 0 0
Biosynthesis of E-series 18(S)-resolvins R-HSA-9018896 9.693126e-01 0.014 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.693126e-01 0.014 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 9.693126e-01 0.014 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 9.693126e-01 0.014 0 0
Basigin interactions R-HSA-210991 9.693126e-01 0.014 0 0
Lagging Strand Synthesis R-HSA-69186 9.693126e-01 0.014 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 9.693126e-01 0.014 0 0
Gap junction trafficking R-HSA-190828 9.696912e-01 0.013 0 0
Surfactant metabolism R-HSA-5683826 9.696912e-01 0.013 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.701260e-01 0.013 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.701260e-01 0.013 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.701260e-01 0.013 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.701260e-01 0.013 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.712273e-01 0.013 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 9.715132e-01 0.013 0 0
PPARA activates gene expression R-HSA-1989781 9.717043e-01 0.012 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.726128e-01 0.012 0 0
Interleukin-10 signaling R-HSA-6783783 9.728098e-01 0.012 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 9.731640e-01 0.012 0 0
Assembly Of The HIV Virion R-HSA-175474 9.731640e-01 0.012 0 0
Serine metabolism R-HSA-977347 9.731640e-01 0.012 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.731640e-01 0.012 0 0
Hyaluronan metabolism R-HSA-2142845 9.733265e-01 0.012 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.733265e-01 0.012 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.733265e-01 0.012 0 0
Neuronal System R-HSA-112316 9.735321e-01 0.012 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.752659e-01 0.011 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.761944e-01 0.010 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.761944e-01 0.010 0 0
PERK regulates gene expression R-HSA-381042 9.761944e-01 0.010 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.761944e-01 0.010 0 0
ER-Phagosome pathway R-HSA-1236974 9.761955e-01 0.010 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 9.765323e-01 0.010 0 0
Biosynthesis of D-series resolvins R-HSA-9018676 9.765323e-01 0.010 0 0
Ethanol oxidation R-HSA-71384 9.765323e-01 0.010 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.765323e-01 0.010 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.776735e-01 0.010 0 0
Triglyceride metabolism R-HSA-8979227 9.785165e-01 0.009 0 0
Regulation of beta-cell development R-HSA-186712 9.785165e-01 0.009 0 0
Glycosphingolipid transport R-HSA-9845576 9.787628e-01 0.009 0 0
G1/S-Specific Transcription R-HSA-69205 9.787628e-01 0.009 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 9.794779e-01 0.009 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 9.794779e-01 0.009 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.794779e-01 0.009 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 9.794779e-01 0.009 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.794779e-01 0.009 0 0
Biosynthesis of maresins R-HSA-9018682 9.794779e-01 0.009 0 0
G1/S Transition R-HSA-69206 9.795108e-01 0.009 0 0
Cellular response to chemical stress R-HSA-9711123 9.797239e-01 0.009 0 0
GPER1 signaling R-HSA-9634597 9.798568e-01 0.009 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 9.801713e-01 0.009 0 0
GABA receptor activation R-HSA-977443 9.804654e-01 0.009 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.804654e-01 0.009 0 0
O-glycosylation of TSR domain-containing proteins R-HSA-5173214 9.810618e-01 0.008 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.810618e-01 0.008 0 0
Cleavage of the damaged purine R-HSA-110331 9.810618e-01 0.008 0 0
Degradation of AXIN R-HSA-4641257 9.810618e-01 0.008 0 0
Collagen chain trimerization R-HSA-8948216 9.810618e-01 0.008 0 0
Interferon Signaling R-HSA-913531 9.815091e-01 0.008 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.818354e-01 0.008 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 9.818683e-01 0.008 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 9.818683e-01 0.008 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.820540e-01 0.008 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 9.820540e-01 0.008 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.820540e-01 0.008 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.820540e-01 0.008 0 0
Synthesis of dolichyl-phosphate R-HSA-446199 9.820540e-01 0.008 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.820540e-01 0.008 0 0
Complex III assembly R-HSA-9865881 9.820540e-01 0.008 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.820540e-01 0.008 0 0
Interleukin-6 family signaling R-HSA-6783589 9.820540e-01 0.008 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.821110e-01 0.008 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.822464e-01 0.008 0 0
Aquaporin-mediated transport R-HSA-445717 9.822464e-01 0.008 0 0
Collagen degradation R-HSA-1442490 9.822464e-01 0.008 0 0
Depurination R-HSA-73927 9.831183e-01 0.007 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 9.832466e-01 0.007 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 9.832518e-01 0.007 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 9.843069e-01 0.007 0 0
Alpha-oxidation of phytanate R-HSA-389599 9.843069e-01 0.007 0 0
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives R-HSA-9027604 9.843069e-01 0.007 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.843069e-01 0.007 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.843069e-01 0.007 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.849572e-01 0.007 0 0
Pentose phosphate pathway R-HSA-71336 9.849572e-01 0.007 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.849572e-01 0.007 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.850582e-01 0.007 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.852014e-01 0.006 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.852493e-01 0.006 0 0
MET activates PTK2 signaling R-HSA-8874081 9.862770e-01 0.006 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 9.862770e-01 0.006 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.862770e-01 0.006 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.862770e-01 0.006 0 0
Attachment of bacteria to epithelial cells R-HSA-9638630 9.862770e-01 0.006 0 0
Abacavir ADME R-HSA-2161522 9.862770e-01 0.006 0 0
Sphingolipid catabolism R-HSA-9845614 9.862770e-01 0.006 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.862770e-01 0.006 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 9.866005e-01 0.006 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.867164e-01 0.006 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.867164e-01 0.006 0 0
Transmission across Chemical Synapses R-HSA-112315 9.878974e-01 0.005 0 0
Packaging Of Telomere Ends R-HSA-171306 9.879999e-01 0.005 0 0
Biosynthesis of DPAn-3 SPMs R-HSA-9025094 9.879999e-01 0.005 0 0
Triglyceride biosynthesis R-HSA-75109 9.879999e-01 0.005 0 0
Synthesis of PE R-HSA-1483213 9.879999e-01 0.005 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 9.879999e-01 0.005 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.879999e-01 0.005 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.880428e-01 0.005 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.880428e-01 0.005 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.880428e-01 0.005 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.880685e-01 0.005 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.880685e-01 0.005 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 9.880685e-01 0.005 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.883915e-01 0.005 0 0
Potassium Channels R-HSA-1296071 9.885561e-01 0.005 0 0
Platelet homeostasis R-HSA-418346 9.889390e-01 0.005 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.892413e-01 0.005 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.892413e-01 0.005 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 9.893791e-01 0.005 0 0
Translation of Structural Proteins R-HSA-9683701 9.893791e-01 0.005 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.894447e-01 0.005 0 0
Telomere Maintenance R-HSA-157579 9.894740e-01 0.005 0 0
Prednisone ADME R-HSA-9757110 9.895066e-01 0.005 0 0
Insulin receptor recycling R-HSA-77387 9.895066e-01 0.005 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 9.895066e-01 0.005 0 0
Neutrophil degranulation R-HSA-6798695 9.895813e-01 0.005 0 0
Gene Silencing by RNA R-HSA-211000 9.897936e-01 0.004 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.899865e-01 0.004 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.903223e-01 0.004 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 9.903236e-01 0.004 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.905489e-01 0.004 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.905489e-01 0.004 0 0
Depyrimidination R-HSA-73928 9.905489e-01 0.004 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.905860e-01 0.004 0 0
DNA methylation R-HSA-5334118 9.908242e-01 0.004 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.908242e-01 0.004 0 0
Biosynthesis of EPA-derived SPMs R-HSA-9018679 9.908242e-01 0.004 0 0
Termination of translesion DNA synthesis R-HSA-5656169 9.908242e-01 0.004 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 9.908242e-01 0.004 0 0
Glucagon-type ligand receptors R-HSA-420092 9.908242e-01 0.004 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 9.908242e-01 0.004 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.910263e-01 0.004 0 0
PKR-mediated signaling R-HSA-9833482 9.912852e-01 0.004 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 9.913005e-01 0.004 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.915924e-01 0.004 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.919764e-01 0.003 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.919764e-01 0.003 0 0
Proteasome assembly R-HSA-9907900 9.925229e-01 0.003 0 0
Dual incision in TC-NER R-HSA-6782135 9.929764e-01 0.003 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 9.929840e-01 0.003 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.929840e-01 0.003 0 0
Biosynthesis of DPA-derived SPMs R-HSA-9018683 9.929840e-01 0.003 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.929840e-01 0.003 0 0
Cargo concentration in the ER R-HSA-5694530 9.929840e-01 0.003 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.931633e-01 0.003 0 0
HCMV Early Events R-HSA-9609690 9.932818e-01 0.003 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.933445e-01 0.003 0 0
Somitogenesis R-HSA-9824272 9.933524e-01 0.003 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.937515e-01 0.003 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 9.937525e-01 0.003 0 0
DAG1 glycosylations R-HSA-8931838 9.938651e-01 0.003 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.938651e-01 0.003 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.940916e-01 0.003 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.940916e-01 0.003 0 0
G alpha (q) signalling events R-HSA-416476 9.942460e-01 0.003 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.943378e-01 0.002 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 9.946356e-01 0.002 0 0
Recycling of bile acids and salts R-HSA-159418 9.946356e-01 0.002 0 0
Co-inhibition by PD-1 R-HSA-389948 9.948285e-01 0.002 0 0
G alpha (s) signalling events R-HSA-418555 9.950417e-01 0.002 0 0
Signaling by NOTCH4 R-HSA-9013694 9.950812e-01 0.002 0 0
Phospholipid metabolism R-HSA-1483257 9.951719e-01 0.002 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.953094e-01 0.002 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.953362e-01 0.002 0 0
Mitochondrial protein import R-HSA-1268020 9.954417e-01 0.002 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 9.954417e-01 0.002 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.955104e-01 0.002 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 9.955561e-01 0.002 0 0
Iron uptake and transport R-HSA-917937 9.955561e-01 0.002 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.955561e-01 0.002 0 0
Signaling by NOTCH R-HSA-157118 9.955670e-01 0.002 0 0
DNA Damage Bypass R-HSA-73893 9.958581e-01 0.002 0 0
eNOS activation R-HSA-203615 9.958985e-01 0.002 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.958985e-01 0.002 0 0
Gap junction assembly R-HSA-190861 9.958985e-01 0.002 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.958985e-01 0.002 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.958985e-01 0.002 0 0
Signal amplification R-HSA-392518 9.958985e-01 0.002 0 0
RA biosynthesis pathway R-HSA-5365859 9.958985e-01 0.002 0 0
Mitophagy R-HSA-5205647 9.958985e-01 0.002 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.959045e-01 0.002 0 0
Synthesis of DNA R-HSA-69239 9.959134e-01 0.002 0 0
Translation of Structural Proteins R-HSA-9694635 9.963767e-01 0.002 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.964137e-01 0.002 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.964137e-01 0.002 0 0
Regulation of Apoptosis R-HSA-169911 9.964137e-01 0.002 0 0
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775 9.964137e-01 0.002 0 0
ABC transporter disorders R-HSA-5619084 9.967300e-01 0.001 0 0
The phototransduction cascade R-HSA-2514856 9.967355e-01 0.001 0 0
ER to Golgi Anterograde Transport R-HSA-199977 9.967548e-01 0.001 0 0
HSF1 activation R-HSA-3371511 9.968643e-01 0.001 0 0
ABC-family proteins mediated transport R-HSA-382556 9.969986e-01 0.001 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.970498e-01 0.001 0 0
Voltage gated Potassium channels R-HSA-1296072 9.972582e-01 0.001 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.972582e-01 0.001 0 0
NCAM1 interactions R-HSA-419037 9.972582e-01 0.001 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.972582e-01 0.001 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.972582e-01 0.001 0 0
Lysine catabolism R-HSA-71064 9.972582e-01 0.001 0 0
Metabolism of folate and pterines R-HSA-196757 9.972582e-01 0.001 0 0
Parasite infection R-HSA-9664407 9.973633e-01 0.001 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.973633e-01 0.001 0 0
Leishmania phagocytosis R-HSA-9664417 9.973633e-01 0.001 0 0
tRNA processing R-HSA-72306 9.974566e-01 0.001 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.976027e-01 0.001 0 0
Elastic fibre formation R-HSA-1566948 9.976027e-01 0.001 0 0
Biofilm formation R-HSA-9931953 9.976027e-01 0.001 0 0
HCMV Infection R-HSA-9609646 9.976466e-01 0.001 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.977286e-01 0.001 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.979039e-01 0.001 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.979039e-01 0.001 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.979039e-01 0.001 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.980024e-01 0.001 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.981096e-01 0.001 0 0
RSV-host interactions R-HSA-9833110 9.981234e-01 0.001 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.981673e-01 0.001 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.981673e-01 0.001 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.982069e-01 0.001 0 0
ECM proteoglycans R-HSA-3000178 9.983088e-01 0.001 0 0
Interferon alpha/beta signaling R-HSA-909733 9.983352e-01 0.001 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.983976e-01 0.001 0 0
Dectin-2 family R-HSA-5621480 9.984104e-01 0.001 0 0
Synthesis of PA R-HSA-1483166 9.984104e-01 0.001 0 0
Peptide hormone metabolism R-HSA-2980736 9.986142e-01 0.001 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.986420e-01 0.001 0 0
Peroxisomal protein import R-HSA-9033241 9.987515e-01 0.001 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.987750e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.987909e-01 0.001 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.988360e-01 0.001 0 0
Parasitic Infection Pathways R-HSA-9824443 9.988846e-01 0.000 0 0
Leishmania infection R-HSA-9658195 9.988846e-01 0.000 0 0
RAB geranylgeranylation R-HSA-8873719 9.988939e-01 0.000 0 0
tRNA Aminoacylation R-HSA-379724 9.988939e-01 0.000 0 0
Defective pyroptosis R-HSA-9710421 9.989290e-01 0.000 0 0
Defensins R-HSA-1461973 9.989290e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.990202e-01 0.000 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.990636e-01 0.000 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.990636e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.990698e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.991531e-01 0.000 0 0
Neurotransmitter release cycle R-HSA-112310 9.991625e-01 0.000 0 0
Base Excision Repair R-HSA-73884 9.991625e-01 0.000 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.991813e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.992298e-01 0.000 0 0
Ion transport by P-type ATPases R-HSA-936837 9.993196e-01 0.000 0 0
SLC transporter disorders R-HSA-5619102 9.993582e-01 0.000 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.993742e-01 0.000 0 0
Synthesis of PC R-HSA-1483191 9.993742e-01 0.000 0 0
HCMV Late Events R-HSA-9610379 9.994169e-01 0.000 0 0
Amyloid fiber formation R-HSA-977225 9.994522e-01 0.000 0 0
Gluconeogenesis R-HSA-70263 9.994529e-01 0.000 0 0
Neddylation R-HSA-8951664 9.994712e-01 0.000 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.995216e-01 0.000 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.995216e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.995283e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.995283e-01 0.000 0 0
Azathioprine ADME R-HSA-9748787 9.995818e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.995826e-01 0.000 0 0
Complex IV assembly R-HSA-9864848 9.996344e-01 0.000 0 0
COPII-mediated vesicle transport R-HSA-204005 9.996734e-01 0.000 0 0
Protein localization R-HSA-9609507 9.996982e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.997112e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.997112e-01 0.000 0 0
Hemostasis R-HSA-109582 9.997287e-01 0.000 0 0
Chaperonin-mediated protein folding R-HSA-390466 9.997544e-01 0.000 0 0
Viral Infection Pathways R-HSA-9824446 9.997721e-01 0.000 0 0
Immune System R-HSA-168256 9.997769e-01 0.000 1 0
Formation of the cornified envelope R-HSA-6809371 9.997823e-01 0.000 0 0
Paracetamol ADME R-HSA-9753281 9.997864e-01 0.000 0 0
G alpha (z) signalling events R-HSA-418597 9.997864e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.998393e-01 0.000 0 0
Sialic acid metabolism R-HSA-4085001 9.998753e-01 0.000 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.998753e-01 0.000 0 0
Protein folding R-HSA-391251 9.998775e-01 0.000 0 0
Metabolism of polyamines R-HSA-351202 9.998909e-01 0.000 0 0
DNA Replication R-HSA-69306 9.999012e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.999047e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.999161e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.999271e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999290e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.999317e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.999363e-01 0.000 0 0
Latent infection - Other responses of Mtb to phagocytosis R-HSA-1222499 9.999443e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.999458e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.999520e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999550e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.999575e-01 0.000 0 0
Metabolism of steroid hormones R-HSA-196071 9.999575e-01 0.000 0 0
Pyruvate metabolism R-HSA-70268 9.999649e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999690e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999691e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.999716e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.999728e-01 0.000 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.999731e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999754e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999759e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999764e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.999810e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.999855e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.999871e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999884e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999897e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.999903e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999904e-01 0.000 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.999935e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999952e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999957e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999966e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.999968e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.999968e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.999971e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999976e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999977e-01 0.000 0 0
Translation R-HSA-72766 9.999978e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999994e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999994e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999995e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999996e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999998e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999998e-01 0.000 0 0
Post-translational protein modification R-HSA-597592 9.999999e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999999e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999999e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999999e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 1.000000e+00 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Keratinization R-HSA-6805567 1.000000e+00 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 1.000000e+00 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Regulation of Complement cascade R-HSA-977606 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Diseases of glycosylation R-HSA-3781865 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Mitochondrial translation R-HSA-5368287 1.000000e+00 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 1.000000e+00 0.000 0 0
Complement cascade R-HSA-166658 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
Respiratory electron transport R-HSA-611105 1.000000e+00 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 1.000000e+00 0.000 0 0
Infectious disease R-HSA-5663205 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Disease R-HSA-1643685 1.000000e+00 0.000 1 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Metabolism of nucleotides R-HSA-15869 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 -0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Cell Cycle, Mitotic R-HSA-69278 1.110223e-16 15.955 0 0
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 2.442491e-15 14.612 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 8.326673e-15 14.080 0 0
Cell Cycle Checkpoints R-HSA-69620 3.486100e-14 13.458 0 0
Nervous system development R-HSA-9675108 3.552714e-14 13.449 0 0
Signaling by ROBO receptors R-HSA-376176 6.261658e-14 13.203 0 0
HSF1-dependent transactivation R-HSA-3371571 6.831202e-13 12.166 0 0
Mitotic Prophase R-HSA-68875 2.582601e-12 11.588 0 0
Eukaryotic Translation Initiation R-HSA-72613 3.505085e-12 11.455 0 0
Cap-dependent Translation Initiation R-HSA-72737 3.505085e-12 11.455 0 0
HSF1 activation R-HSA-3371511 3.364309e-12 11.473 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 3.842038e-12 11.415 0 0
G2/M Checkpoints R-HSA-69481 4.884204e-12 11.311 0 0
Cellular Senescence R-HSA-2559583 5.753842e-12 11.240 0 0
Eukaryotic Translation Elongation R-HSA-156842 6.826317e-12 11.166 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.424350e-11 10.846 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.048439e-11 10.689 0 0
Attenuation phase R-HSA-3371568 2.156764e-11 10.666 0 0
Signal Transduction R-HSA-162582 2.791645e-11 10.554 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.779088e-11 10.423 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.779088e-11 10.423 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 6.035816e-11 10.219 1 0
Formation of a pool of free 40S subunits R-HSA-72689 7.726375e-11 10.112 0 0
G2/M DNA damage checkpoint R-HSA-69473 9.790802e-11 10.009 0 0
Peptide chain elongation R-HSA-156902 1.050430e-10 9.979 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.214742e-10 9.916 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.241662e-10 9.906 0 0
Metabolism of RNA R-HSA-8953854 1.350271e-10 9.870 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.747755e-10 9.758 0 0
DNA Replication Pre-Initiation R-HSA-69002 2.293247e-10 9.640 0 0
mRNA Splicing - Major Pathway R-HSA-72163 5.469224e-10 9.262 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 8.064251e-10 9.093 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 8.551615e-10 9.068 0 0
Cell-Cell communication R-HSA-1500931 1.112826e-09 8.954 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.411969e-09 8.850 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.454666e-09 8.837 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.688403e-09 8.773 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 2.344366e-09 8.630 0 0
Influenza Infection R-HSA-168255 2.670726e-09 8.573 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 3.080367e-09 8.511 0 0
mRNA Splicing R-HSA-72172 3.005969e-09 8.522 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.470836e-09 8.460 0 0
DNA Double Strand Break Response R-HSA-5693606 3.625008e-09 8.441 0 0
Meiosis R-HSA-1500620 7.285516e-09 8.138 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 7.483413e-09 8.126 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 7.483413e-09 8.126 0 0
ESR-mediated signaling R-HSA-8939211 7.973732e-09 8.098 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 8.199400e-09 8.086 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 8.261802e-09 8.083 0 0
Cell junction organization R-HSA-446728 8.580894e-09 8.066 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 8.978636e-09 8.047 0 0
Eukaryotic Translation Termination R-HSA-72764 1.215022e-08 7.915 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.398057e-08 7.854 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.425402e-08 7.846 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.645298e-08 7.784 0 0
Meiotic synapsis R-HSA-1221632 1.757899e-08 7.755 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.757899e-08 7.755 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.876960e-08 7.727 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.848157e-08 7.733 0 0
Ribosome-associated quality control R-HSA-9948299 2.045917e-08 7.689 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 2.034245e-08 7.692 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 2.063058e-08 7.685 0 0
Assembly of the pre-replicative complex R-HSA-68867 2.102659e-08 7.677 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.248645e-08 7.488 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 4.032409e-08 7.394 0 0
Mitotic Anaphase R-HSA-68882 4.050432e-08 7.392 0 0
Meiotic recombination R-HSA-912446 4.064257e-08 7.391 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 4.437373e-08 7.353 0 0
Selenocysteine synthesis R-HSA-2408557 4.312220e-08 7.365 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 4.621396e-08 7.335 0 0
Apoptosis R-HSA-109581 5.781229e-08 7.238 0 0
Viral mRNA Translation R-HSA-192823 6.437757e-08 7.191 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.387602e-08 7.131 0 0
Translation initiation complex formation R-HSA-72649 9.682954e-08 7.014 0 0
DNA methylation R-HSA-5334118 1.169285e-07 6.932 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.215592e-07 6.915 0 0
HDACs deacetylate histones R-HSA-3214815 1.277571e-07 6.894 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.392400e-07 6.856 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.557565e-07 6.808 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.675920e-07 6.776 0 0
Chromatin organization R-HSA-4839726 1.926961e-07 6.715 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.107790e-07 6.676 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 2.051907e-07 6.688 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 2.173031e-07 6.663 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.636259e-07 6.579 0 0
DNA Replication R-HSA-69306 2.636259e-07 6.579 0 0
Defective pyroptosis R-HSA-9710421 2.762585e-07 6.559 0 0
Mitotic Prometaphase R-HSA-68877 3.317768e-07 6.479 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 3.472284e-07 6.459 0 0
Intracellular signaling by second messengers R-HSA-9006925 4.039306e-07 6.394 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.451400e-07 6.352 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 4.733667e-07 6.325 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 4.733667e-07 6.325 0 0
Cellular response to starvation R-HSA-9711097 5.427081e-07 6.265 0 0
Homology Directed Repair R-HSA-5693538 5.718980e-07 6.243 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 6.609040e-07 6.180 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.609040e-07 6.180 0 0
Diseases of programmed cell death R-HSA-9645723 6.522214e-07 6.186 0 0
Apoptotic execution phase R-HSA-75153 6.609040e-07 6.180 0 0
Chromatin modifying enzymes R-HSA-3247509 8.418413e-07 6.075 0 0
Developmental Biology R-HSA-1266738 8.859871e-07 6.053 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.005318e-06 5.998 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.141942e-06 5.942 0 0
Packaging Of Telomere Ends R-HSA-171306 1.423267e-06 5.847 0 0
Adherens junctions interactions R-HSA-418990 1.480297e-06 5.830 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.585891e-06 5.800 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.491588e-06 5.826 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.619326e-06 5.791 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.680654e-06 5.775 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.704221e-06 5.768 0 0
RNA Polymerase I Transcription R-HSA-73864 2.239855e-06 5.650 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.578201e-06 5.589 0 0
HCMV Early Events R-HSA-9609690 2.578691e-06 5.589 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 2.578201e-06 5.589 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 2.552504e-06 5.593 0 0
Separation of Sister Chromatids R-HSA-2467813 2.959942e-06 5.529 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 3.164314e-06 5.500 0 0
Recycling pathway of L1 R-HSA-437239 3.348409e-06 5.475 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.373568e-06 5.472 0 0
Programmed Cell Death R-HSA-5357801 3.655177e-06 5.437 0 0
Chaperone Mediated Autophagy R-HSA-9613829 4.016724e-06 5.396 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 4.397734e-06 5.357 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 4.543818e-06 5.343 0 0
Reproduction R-HSA-1474165 4.888982e-06 5.311 0 0
Membrane Trafficking R-HSA-199991 4.889371e-06 5.311 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 5.093521e-06 5.293 0 0
Cell-cell junction organization R-HSA-421270 5.107451e-06 5.292 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 5.416779e-06 5.266 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 5.457118e-06 5.263 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 6.471316e-06 5.189 0 0
Nucleosome assembly R-HSA-774815 7.514305e-06 5.124 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 7.514305e-06 5.124 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.571350e-06 5.121 0 0
Regulation of TP53 Degradation R-HSA-6804757 7.883674e-06 5.103 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 9.108115e-06 5.041 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 9.421349e-06 5.026 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.652536e-06 5.015 0 0
Nuclear Envelope Breakdown R-HSA-2980766 9.999806e-06 5.000 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.039948e-05 4.983 0 0
Signaling by ALK in cancer R-HSA-9700206 1.039948e-05 4.983 0 0
Gene Silencing by RNA R-HSA-211000 1.039948e-05 4.983 0 0
Cleavage of the damaged purine R-HSA-110331 1.041775e-05 4.982 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.183565e-05 4.927 0 0
Depurination R-HSA-73927 1.365355e-05 4.865 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.392770e-05 4.856 0 0
Post NMDA receptor activation events R-HSA-438064 1.414098e-05 4.850 0 0
Interleukin-12 signaling R-HSA-9020591 1.424156e-05 4.846 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.586981e-05 4.799 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.609194e-05 4.793 0 0
Viral Infection Pathways R-HSA-9824446 1.906904e-05 4.720 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.917676e-05 4.717 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.923223e-05 4.716 0 0
L1CAM interactions R-HSA-373760 2.022687e-05 4.694 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 2.029569e-05 4.693 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.330070e-05 4.633 0 0
Aggrephagy R-HSA-9646399 2.291345e-05 4.640 0 0
Ub-specific processing proteases R-HSA-5689880 2.228209e-05 4.652 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.394403e-05 4.621 0 0
SARS-CoV-1 Infection R-HSA-9678108 2.779249e-05 4.556 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.892593e-05 4.539 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 3.129140e-05 4.505 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.178468e-05 4.498 0 0
Signaling by PTK6 R-HSA-8848021 3.409193e-05 4.467 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 3.409193e-05 4.467 0 0
Selenoamino acid metabolism R-HSA-2408522 3.506117e-05 4.455 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.580805e-05 4.446 0 0
HCMV Infection R-HSA-9609646 3.771336e-05 4.424 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 4.722738e-05 4.326 0 0
Depyrimidination R-HSA-73928 4.722738e-05 4.326 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 4.965496e-05 4.304 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.508005e-05 4.259 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 5.604314e-05 4.251 0 0
Deubiquitination R-HSA-5688426 5.854075e-05 4.233 0 0
Signaling by ERBB2 R-HSA-1227986 5.875070e-05 4.231 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 6.445891e-05 4.191 0 0
TCF dependent signaling in response to WNT R-HSA-201681 6.461715e-05 4.190 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 6.541619e-05 4.184 0 0
Activation of the pre-replicative complex R-HSA-68962 7.276414e-05 4.138 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 7.276414e-05 4.138 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 7.716646e-05 4.113 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 8.035037e-05 4.095 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 8.267229e-05 4.083 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 8.520637e-05 4.070 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 8.594461e-05 4.066 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 8.708466e-05 4.060 0 0
G2/M Transition R-HSA-69275 8.727000e-05 4.059 0 0
EGFR downregulation R-HSA-182971 9.517146e-05 4.021 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.037780e-04 3.984 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.012331e-04 3.995 0 0
Amyloid fiber formation R-HSA-977225 9.416054e-05 4.026 0 0
Interleukin-12 family signaling R-HSA-447115 1.039990e-04 3.983 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.040337e-04 3.983 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.061399e-04 3.974 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.061399e-04 3.974 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 1.086263e-04 3.964 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.134377e-04 3.945 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.134377e-04 3.945 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.134377e-04 3.945 0 0
Signaling by RAS mutants R-HSA-6802949 1.134377e-04 3.945 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.252214e-04 3.902 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.274433e-04 3.895 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.293940e-04 3.888 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.293940e-04 3.888 0 0
Interferon Signaling R-HSA-913531 1.397941e-04 3.855 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.583424e-04 3.800 0 0
Base Excision Repair R-HSA-73884 1.610865e-04 3.793 0 0
G1/S Transition R-HSA-69206 1.717818e-04 3.765 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.744097e-04 3.758 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.789779e-04 3.747 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.789779e-04 3.747 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.940098e-04 3.712 0 0
Striated Muscle Contraction R-HSA-390522 2.016097e-04 3.695 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 2.016097e-04 3.695 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.236889e-04 3.650 0 0
Chromosome Maintenance R-HSA-73886 2.157055e-04 3.666 0 0
Telomere Maintenance R-HSA-157579 2.236889e-04 3.650 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 2.265246e-04 3.645 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.421702e-04 3.616 0 0
Signaling by EGFR R-HSA-177929 2.505074e-04 3.601 0 0
Signaling by WNT R-HSA-195721 2.773764e-04 3.557 0 0
Activation of BH3-only proteins R-HSA-114452 2.788103e-04 3.555 0 0
HATs acetylate histones R-HSA-3214847 2.901769e-04 3.537 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 2.916653e-04 3.535 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 3.048336e-04 3.516 0 0
Autophagy R-HSA-9612973 3.083018e-04 3.511 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 3.154518e-04 3.501 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.191521e-04 3.496 0 0
Glycolysis R-HSA-70171 3.295255e-04 3.482 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 3.354416e-04 3.474 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 3.354416e-04 3.474 0 0
HIV Life Cycle R-HSA-162587 3.401114e-04 3.468 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 3.598484e-04 3.444 0 0
mRNA 3'-end processing R-HSA-72187 3.598484e-04 3.444 0 0
Signaling by VEGF R-HSA-194138 3.798014e-04 3.420 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 3.822034e-04 3.418 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.930180e-04 3.406 0 0
Signaling by RAF1 mutants R-HSA-9656223 4.215476e-04 3.375 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 4.411089e-04 3.355 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 4.483101e-04 3.348 0 0
Regulation of TP53 Activity R-HSA-5633007 4.537472e-04 3.343 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 4.906503e-04 3.309 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 4.906503e-04 3.309 0 0
Regulation of PTEN localization R-HSA-8948747 5.058881e-04 3.296 0 0
mTORC1-mediated signalling R-HSA-166208 5.189610e-04 3.285 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 6.178834e-04 3.209 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 6.178834e-04 3.209 0 0
S Phase R-HSA-69242 5.903297e-04 3.229 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 6.343389e-04 3.198 0 0
Spry regulation of FGF signaling R-HSA-1295596 6.491989e-04 3.188 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 6.491989e-04 3.188 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 6.491989e-04 3.188 0 0
Host Interactions of HIV factors R-HSA-162909 6.596046e-04 3.181 0 0
Late Phase of HIV Life Cycle R-HSA-162599 6.729996e-04 3.172 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.849932e-04 3.164 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 7.098069e-04 3.149 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.098069e-04 3.149 0 0
Selective autophagy R-HSA-9663891 7.385175e-04 3.132 0 0
Clathrin-mediated endocytosis R-HSA-8856828 7.411019e-04 3.130 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 7.739102e-04 3.111 0 0
Late endosomal microautophagy R-HSA-9615710 7.913717e-04 3.102 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 8.262395e-04 3.083 0 0
Formation of annular gap junctions R-HSA-196025 8.262395e-04 3.083 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 8.262395e-04 3.083 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 8.262395e-04 3.083 0 0
Regulation of CDH1 Function R-HSA-9764561 8.328500e-04 3.079 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 8.718455e-04 3.060 0 0
HIV Infection R-HSA-162906 8.798698e-04 3.056 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 8.903433e-04 3.050 0 0
Negative regulation of MET activity R-HSA-6807004 9.184883e-04 3.037 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.201172e-03 2.920 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.201172e-03 2.920 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.201172e-03 2.920 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.227707e-03 2.911 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.193089e-03 2.923 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.193089e-03 2.923 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.077575e-03 2.968 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.222676e-03 2.913 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 1.281044e-03 2.892 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.272675e-03 2.895 0 0
Gap junction degradation R-HSA-190873 1.284117e-03 2.891 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.284117e-03 2.891 0 0
MAP2K and MAPK activation R-HSA-5674135 1.285994e-03 2.891 0 0
Kinesins R-HSA-983189 1.316140e-03 2.881 0 0
PKR-mediated signaling R-HSA-9833482 1.324193e-03 2.878 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.340053e-03 2.873 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.340053e-03 2.873 0 0
HCMV Late Events R-HSA-9610379 1.342648e-03 2.872 0 0
Metalloprotease DUBs R-HSA-5689901 1.401374e-03 2.853 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 1.405854e-03 2.852 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.522385e-03 2.817 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.533010e-03 2.814 0 0
MTOR signalling R-HSA-165159 1.533010e-03 2.814 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.550226e-03 2.810 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 1.550226e-03 2.810 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.689948e-03 2.772 0 0
Signaling by TGFB family members R-HSA-9006936 1.733721e-03 2.761 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.771198e-03 2.752 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.820014e-03 2.740 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.844890e-03 2.734 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 1.859593e-03 2.731 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.016968e-03 2.695 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.016968e-03 2.695 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 2.016968e-03 2.695 0 0
Translation R-HSA-72766 2.017961e-03 2.695 0 0
Co-inhibition by PD-1 R-HSA-389948 2.045526e-03 2.689 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.141879e-03 2.669 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 2.165038e-03 2.665 0 0
NRIF signals cell death from the nucleus R-HSA-205043 2.165038e-03 2.665 0 0
Macroautophagy R-HSA-1632852 2.212314e-03 2.655 0 0
Cytokine Signaling in Immune system R-HSA-1280215 2.274668e-03 2.643 1 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.491107e-03 2.604 0 0
Nuclear import of Rev protein R-HSA-180746 2.694080e-03 2.570 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 2.754480e-03 2.560 0 0
Translesion Synthesis by POLH R-HSA-110320 2.769805e-03 2.558 0 0
DNA Repair R-HSA-73894 2.816111e-03 2.550 0 0
snRNP Assembly R-HSA-191859 2.904503e-03 2.537 0 0
Metabolism of non-coding RNA R-HSA-194441 2.904503e-03 2.537 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 2.911557e-03 2.536 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.911557e-03 2.536 0 0
Glucose metabolism R-HSA-70326 2.918958e-03 2.535 0 0
AURKA Activation by TPX2 R-HSA-8854518 3.005283e-03 2.522 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 3.013723e-03 2.521 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 3.013723e-03 2.521 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.057258e-03 2.515 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 3.106820e-03 2.508 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.237546e-03 2.490 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.237546e-03 2.490 0 0
Signaling by ERBB4 R-HSA-1236394 3.449188e-03 2.462 0 0
Nephrin family interactions R-HSA-373753 3.532812e-03 2.452 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 3.252356e-03 2.488 0 0
Signaling by FGFR2 R-HSA-5654738 3.068995e-03 2.513 0 0
Death Receptor Signaling R-HSA-73887 3.731437e-03 2.428 0 0
FLT3 signaling in disease R-HSA-9682385 3.833696e-03 2.416 1 0
rRNA processing R-HSA-72312 3.771815e-03 2.423 0 0
HDMs demethylate histones R-HSA-3214842 3.836560e-03 2.416 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 3.840744e-03 2.416 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 3.840744e-03 2.416 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 3.844222e-03 2.415 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 3.844222e-03 2.415 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 3.844222e-03 2.415 0 0
Centrosome maturation R-HSA-380287 3.881735e-03 2.411 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.911524e-03 2.408 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.911524e-03 2.408 0 0
Vesicle-mediated transport R-HSA-5653656 4.000710e-03 2.398 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 4.532514e-03 2.344 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 4.532514e-03 2.344 0 0
Gap junction trafficking and regulation R-HSA-157858 4.590471e-03 2.338 0 0
Signaling by EGFR in Cancer R-HSA-1643713 4.694038e-03 2.328 0 0
Type I hemidesmosome assembly R-HSA-446107 4.788068e-03 2.320 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 4.979206e-03 2.303 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 4.979206e-03 2.303 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.980574e-03 2.303 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 5.224524e-03 2.282 0 0
VLDLR internalisation and degradation R-HSA-8866427 5.224524e-03 2.282 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 5.306594e-03 2.275 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 5.418587e-03 2.266 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 5.538065e-03 2.257 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.589576e-03 2.253 0 0
Gap junction trafficking R-HSA-190828 5.770223e-03 2.239 0 0
SARS-CoV-2 Infection R-HSA-9694516 5.942592e-03 2.226 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 6.231640e-03 2.205 0 0
EPH-Ephrin signaling R-HSA-2682334 6.340813e-03 2.198 0 0
Signaling by Hippo R-HSA-2028269 6.354313e-03 2.197 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 6.616071e-03 2.179 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 6.616071e-03 2.179 0 0
DAG and IP3 signaling R-HSA-1489509 6.656006e-03 2.177 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 7.300786e-03 2.137 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 7.300786e-03 2.137 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 7.300786e-03 2.137 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 7.300786e-03 2.137 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 8.187900e-03 2.087 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 8.187900e-03 2.087 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 6.936877e-03 2.159 0 0
FGFR2 alternative splicing R-HSA-6803529 6.818993e-03 2.166 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 6.818993e-03 2.166 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 8.177770e-03 2.087 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 8.177770e-03 2.087 0 0
Dual Incision in GG-NER R-HSA-5696400 7.783065e-03 2.109 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 7.250284e-03 2.140 0 0
Orc1 removal from chromatin R-HSA-68949 6.902574e-03 2.161 0 0
Protein ubiquitination R-HSA-8852135 8.581845e-03 2.066 0 0
Chaperonin-mediated protein folding R-HSA-390466 7.265037e-03 2.139 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.916396e-03 2.160 0 0
Synthesis of DNA R-HSA-69239 7.633779e-03 2.117 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 6.936877e-03 2.159 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 6.818993e-03 2.166 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 6.840466e-03 2.165 0 0
MAP kinase activation R-HSA-450294 8.897781e-03 2.051 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 8.187900e-03 2.087 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 9.022522e-03 2.045 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 9.022522e-03 2.045 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 8.394304e-03 2.076 0 0
Regulation of PTEN gene transcription R-HSA-8943724 7.908311e-03 2.102 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 7.250284e-03 2.140 0 0
Muscle contraction R-HSA-397014 8.392043e-03 2.076 0 0
Maturation of protein E R-HSA-9683683 8.187900e-03 2.087 0 0
Maturation of protein E R-HSA-9694493 8.187900e-03 2.087 0 0
Oncogene Induced Senescence R-HSA-2559585 9.102525e-03 2.041 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 9.440060e-03 2.025 0 0
Signal attenuation R-HSA-74749 9.440060e-03 2.025 0 0
Josephin domain DUBs R-HSA-5689877 9.440060e-03 2.025 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 9.440060e-03 2.025 0 0
Pexophagy R-HSA-9664873 9.440060e-03 2.025 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.673446e-03 2.014 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 9.673446e-03 2.014 0 0
Regulation of signaling by CBL R-HSA-912631 9.925623e-03 2.003 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 9.925623e-03 2.003 0 0
Signaling by NOTCH R-HSA-157118 9.984359e-03 2.001 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.003725e-02 1.998 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.066385e-02 1.972 0 0
DNA Damage Bypass R-HSA-73893 1.131800e-02 1.946 0 0
NRAGE signals death through JNK R-HSA-193648 1.132215e-02 1.946 0 0
Budding and maturation of HIV virion R-HSA-162588 1.141060e-02 1.943 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 1.152172e-02 1.938 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.152172e-02 1.938 0 0
Translesion synthesis by REV1 R-HSA-110312 1.152172e-02 1.938 0 0
G alpha (12/13) signalling events R-HSA-416482 1.166335e-02 1.933 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.191793e-02 1.924 0 0
PTEN Regulation R-HSA-6807070 1.200698e-02 1.921 0 0
Long-term potentiation R-HSA-9620244 1.201492e-02 1.920 0 0
Signaling by FGFR R-HSA-190236 1.208708e-02 1.918 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.239497e-02 1.907 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.264952e-02 1.898 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.267672e-02 1.897 0 0
Protein folding R-HSA-391251 1.278314e-02 1.893 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.287791e-02 1.890 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 1.328163e-02 1.877 0 0
MET interacts with TNS proteins R-HSA-8875513 1.328163e-02 1.877 0 0
G0 and Early G1 R-HSA-1538133 1.334624e-02 1.875 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.347873e-02 1.870 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.351874e-02 1.869 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.393350e-02 1.856 0 0
Translesion synthesis by POLI R-HSA-5656121 1.447303e-02 1.839 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 1.447303e-02 1.839 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 1.477525e-02 1.830 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.486456e-02 1.828 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 1.594034e-02 1.798 0 0
Stabilization of p53 R-HSA-69541 1.614871e-02 1.792 0 0
NF-kB is activated and signals survival R-HSA-209560 1.652591e-02 1.782 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.656449e-02 1.781 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.656449e-02 1.781 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.656449e-02 1.781 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.656449e-02 1.781 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.656449e-02 1.781 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.680678e-02 1.775 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.680678e-02 1.775 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 1.708526e-02 1.767 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.720343e-02 1.764 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 1.720343e-02 1.764 0 0
MHC class II antigen presentation R-HSA-2132295 1.721747e-02 1.764 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 1.774572e-02 1.751 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.774572e-02 1.751 0 0
Assembly Of The HIV Virion R-HSA-175474 1.774572e-02 1.751 0 0
RNA Polymerase II Transcription R-HSA-73857 1.788839e-02 1.747 0 0
Translesion synthesis by POLK R-HSA-5655862 1.791273e-02 1.747 0 0
MAPK family signaling cascades R-HSA-5683057 1.803759e-02 1.744 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 1.841321e-02 1.735 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.844267e-02 1.734 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.844267e-02 1.734 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.844385e-02 1.734 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.954215e-02 1.709 0 0
PLC beta mediated events R-HSA-112043 1.961517e-02 1.707 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.965935e-02 1.706 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.965935e-02 1.706 0 0
SARS-CoV Infections R-HSA-9679506 1.977622e-02 1.704 0 0
Infectious disease R-HSA-5663205 2.041578e-02 1.690 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 2.090277e-02 1.680 0 0
FLT3 Signaling R-HSA-9607240 2.090277e-02 1.680 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 2.090277e-02 1.680 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.111305e-02 1.675 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 2.111305e-02 1.675 0 0
IRAK1 recruits IKK complex R-HSA-937039 2.111955e-02 1.675 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 2.111955e-02 1.675 0 0
p75NTR recruits signalling complexes R-HSA-209543 2.111955e-02 1.675 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.117453e-02 1.674 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.138506e-02 1.670 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 2.138506e-02 1.670 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.187422e-02 1.660 0 0
Interleukin-17 signaling R-HSA-448424 2.280779e-02 1.642 0 0
Termination of translesion DNA synthesis R-HSA-5656169 2.284070e-02 1.641 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 2.284070e-02 1.641 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 2.337625e-02 1.631 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 2.337625e-02 1.631 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 2.337625e-02 1.631 0 0
Modulation by Mtb of host immune system R-HSA-9637628 2.337625e-02 1.631 0 0
PCP/CE pathway R-HSA-4086400 2.361529e-02 1.627 0 0
Manipulation of host energy metabolism R-HSA-9636667 3.498379e-02 1.456 0 0
IRS activation R-HSA-74713 3.165429e-02 1.500 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 3.073592e-02 1.512 0 0
ALK mutants bind TKIs R-HSA-9700645 3.073592e-02 1.512 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 3.262172e-02 1.486 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.638756e-02 1.579 0 0
Ephrin signaling R-HSA-3928664 2.638756e-02 1.579 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 3.147906e-02 1.502 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 2.636791e-02 1.579 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.025690e-02 1.519 0 0
Regulation of RAS by GAPs R-HSA-5658442 2.889981e-02 1.539 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 2.504998e-02 1.601 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 3.547812e-02 1.450 0 0
Sema4D in semaphorin signaling R-HSA-400685 3.381485e-02 1.471 0 0
Signaling by MET R-HSA-6806834 2.806716e-02 1.552 0 0
EPHB-mediated forward signaling R-HSA-3928662 3.333412e-02 1.477 0 0
Degradation of DVL R-HSA-4641258 3.036713e-02 1.518 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 3.333412e-02 1.477 0 0
RMTs methylate histone arginines R-HSA-3214858 3.333412e-02 1.477 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.638756e-02 1.579 0 0
Ovarian tumor domain proteases R-HSA-5689896 3.036713e-02 1.518 0 0
Cyclin D associated events in G1 R-HSA-69231 3.333412e-02 1.477 0 0
G1 Phase R-HSA-69236 3.333412e-02 1.477 0 0
Breakdown of the nuclear lamina R-HSA-352238 3.498379e-02 1.456 0 0
Rab regulation of trafficking R-HSA-9007101 3.482378e-02 1.458 0 0
Ca-dependent events R-HSA-111996 2.660245e-02 1.575 0 0
Gene expression (Transcription) R-HSA-74160 2.725549e-02 1.565 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.073592e-02 1.512 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.381485e-02 1.471 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.381485e-02 1.471 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.490006e-02 1.604 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.912772e-02 1.536 0 0
Neurodegenerative Diseases R-HSA-8863678 2.912772e-02 1.536 0 0
G-protein mediated events R-HSA-112040 3.478029e-02 1.459 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.073592e-02 1.512 0 0
TNF signaling R-HSA-75893 2.504998e-02 1.601 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.687290e-02 1.571 0 0
Semaphorin interactions R-HSA-373755 2.397473e-02 1.620 0 0
RUNX2 regulates bone development R-HSA-8941326 2.681650e-02 1.572 0 0
Signaling by FGFR4 R-HSA-5654743 2.983421e-02 1.525 0 0
Transport of connexons to the plasma membrane R-HSA-190872 2.638756e-02 1.579 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 2.691373e-02 1.570 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.591543e-02 1.445 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 3.599355e-02 1.444 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 3.649397e-02 1.438 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 3.649397e-02 1.438 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 3.649397e-02 1.438 0 0
Adaptive Immune System R-HSA-1280218 3.653651e-02 1.437 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 3.711157e-02 1.430 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 3.711157e-02 1.430 0 0
Signaling by FGFR3 R-HSA-5654741 3.711157e-02 1.430 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 3.717100e-02 1.430 0 0
UCH proteinases R-HSA-5689603 3.852915e-02 1.414 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 3.878468e-02 1.411 0 0
Cellular response to chemical stress R-HSA-9711123 3.907555e-02 1.408 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 3.913373e-02 1.407 0 0
Smooth Muscle Contraction R-HSA-445355 3.913373e-02 1.407 0 0
G-protein beta:gamma signalling R-HSA-397795 3.917728e-02 1.407 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 3.917728e-02 1.407 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 3.917728e-02 1.407 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 3.917728e-02 1.407 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 3.917728e-02 1.407 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.931349e-02 1.405 0 0
Folding of actin by CCT/TriC R-HSA-390450 3.931349e-02 1.405 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 3.931349e-02 1.405 0 0
Neutrophil degranulation R-HSA-6798695 3.940112e-02 1.404 0 0
DCC mediated attractive signaling R-HSA-418885 3.959126e-02 1.402 0 0
Protein methylation R-HSA-8876725 3.959126e-02 1.402 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 3.959126e-02 1.402 0 0
p75NTR signals via NF-kB R-HSA-193639 3.959126e-02 1.402 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 3.960145e-02 1.402 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 4.030259e-02 1.395 0 0
Viral Messenger RNA Synthesis R-HSA-168325 4.048954e-02 1.393 0 0
Signaling by Interleukins R-HSA-449147 4.091014e-02 1.388 1 0
mRNA Splicing - Minor Pathway R-HSA-72165 4.117525e-02 1.385 0 0
Regulation of TNFR1 signaling R-HSA-5357905 4.117525e-02 1.385 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 4.139804e-02 1.383 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 4.139804e-02 1.383 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 4.139804e-02 1.383 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 4.295277e-02 1.367 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 4.295277e-02 1.367 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.406148e-02 1.356 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 4.423461e-02 1.354 0 0
tRNA processing in the nucleus R-HSA-6784531 4.423461e-02 1.354 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.463104e-02 1.350 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.490447e-02 1.348 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 4.553312e-02 1.342 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.553312e-02 1.342 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.721360e-02 1.326 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.721360e-02 1.326 0 0
Prolonged ERK activation events R-HSA-169893 4.739968e-02 1.324 0 0
Negative regulation of FLT3 R-HSA-9706369 4.739968e-02 1.324 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 4.782568e-02 1.320 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 4.869321e-02 1.313 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 4.874416e-02 1.312 0 0
Suppression of apoptosis R-HSA-9635465 4.912010e-02 1.309 0 0
ChREBP activates metabolic gene expression R-HSA-163765 4.912010e-02 1.309 0 0
RAF activation R-HSA-5673000 4.970082e-02 1.304 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 4.970082e-02 1.304 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 4.970082e-02 1.304 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 4.970082e-02 1.304 0 0
NOD1/2 Signaling Pathway R-HSA-168638 4.970082e-02 1.304 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 4.977662e-02 1.303 0 0
Antigen processing-Cross presentation R-HSA-1236975 4.977662e-02 1.303 0 0
Signaling by PDGFR in disease R-HSA-9671555 5.042376e-02 1.297 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.078554e-02 1.294 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.165042e-02 1.287 0 0
Signaling by FGFR1 R-HSA-5654736 5.165042e-02 1.287 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 5.269682e-02 1.278 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 5.301315e-02 1.276 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 5.305122e-02 1.275 0 0
Regulation of Apoptosis R-HSA-169911 5.558759e-02 1.255 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 5.558759e-02 1.255 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 5.605632e-02 1.251 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.605632e-02 1.251 0 0
TCR signaling R-HSA-202403 5.639467e-02 1.249 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.775951e-02 1.238 0 0
Regulation of TP53 Expression R-HSA-6804754 5.840964e-02 1.234 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 5.840964e-02 1.234 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 5.840964e-02 1.234 0 0
Signaling by LTK in cancer R-HSA-9842640 5.852460e-02 1.233 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 5.852460e-02 1.233 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 5.852460e-02 1.233 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 5.852460e-02 1.233 0 0
Nef and signal transduction R-HSA-164944 5.852460e-02 1.233 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.863585e-02 1.232 0 0
Activation of RAC1 R-HSA-428540 6.014853e-02 1.221 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 6.014853e-02 1.221 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 6.081446e-02 1.216 0 0
Dual incision in TC-NER R-HSA-6782135 6.134444e-02 1.212 0 0
Response of endothelial cells to shear stress R-HSA-9860931 6.141275e-02 1.212 0 0
Calmodulin induced events R-HSA-111933 6.190018e-02 1.208 0 0
CaM pathway R-HSA-111997 6.190018e-02 1.208 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 6.556234e-02 1.183 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 6.556234e-02 1.183 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 6.556234e-02 1.183 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.603589e-02 1.180 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 6.603614e-02 1.180 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.623632e-02 1.179 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 6.655279e-02 1.177 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 6.743231e-02 1.171 0 0
Degradation of AXIN R-HSA-4641257 6.864320e-02 1.163 0 0
Nucleotide Excision Repair R-HSA-5696398 6.934837e-02 1.159 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 7.233078e-02 1.141 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 7.237502e-02 1.140 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 7.237502e-02 1.140 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 7.237502e-02 1.140 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 7.384804e-02 1.132 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 7.492151e-02 1.125 0 0
IFNG signaling activates MAPKs R-HSA-9732724 7.492151e-02 1.125 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 7.492151e-02 1.125 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 7.591107e-02 1.120 0 0
Generic Transcription Pathway R-HSA-212436 7.753620e-02 1.110 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 7.758958e-02 1.110 0 0
Regulation of PTEN stability and activity R-HSA-8948751 7.819513e-02 1.107 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 7.863826e-02 1.104 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.966123e-02 1.099 0 0
Hedgehog 'off' state R-HSA-5610787 8.032282e-02 1.095 0 0
DNA strand elongation R-HSA-69190 8.055036e-02 1.094 0 0
Diseases of mitotic cell cycle R-HSA-9675126 8.055036e-02 1.094 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 8.143195e-02 1.089 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 8.295512e-02 1.081 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.464924e-02 1.072 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 8.476118e-02 1.072 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 8.575935e-02 1.067 0 0
MET activates PTPN11 R-HSA-8865999 8.575935e-02 1.067 0 0
Frs2-mediated activation R-HSA-170968 8.576127e-02 1.067 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 8.576127e-02 1.067 0 0
Cilium Assembly R-HSA-5617833 8.673409e-02 1.062 0 0
Rap1 signalling R-HSA-392517 8.708844e-02 1.060 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 8.893866e-02 1.051 0 0
Regulation of mitotic cell cycle R-HSA-453276 8.893866e-02 1.051 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.893866e-02 1.051 0 0
Toll-like Receptor Cascades R-HSA-168898 9.038064e-02 1.044 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 9.250359e-02 1.034 0 0
PDGFR mutants bind TKIs R-HSA-9674428 9.250359e-02 1.034 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 9.250359e-02 1.034 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 9.250359e-02 1.034 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 9.250359e-02 1.034 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 9.250359e-02 1.034 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 9.250359e-02 1.034 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 9.250359e-02 1.034 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 1.764552e-01 0.753 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.764552e-01 0.753 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 1.764552e-01 0.753 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.764552e-01 0.753 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 1.764552e-01 0.753 0 0
TICAM1 deficiency - HSE R-HSA-5602566 1.764552e-01 0.753 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.764552e-01 0.753 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 1.161075e-01 0.935 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 1.161075e-01 0.935 0 0
Signaling by MAP2K mutants R-HSA-9652169 1.161075e-01 0.935 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.486661e-01 0.828 0 0
RSK activation R-HSA-444257 9.310143e-02 1.031 0 0
MET receptor recycling R-HSA-8875656 9.310143e-02 1.031 0 0
ARMS-mediated activation R-HSA-170984 1.128944e-01 0.947 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 1.827671e-01 0.738 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.827671e-01 0.738 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 1.827671e-01 0.738 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 1.827671e-01 0.738 0 0
PI3K/AKT activation R-HSA-198203 1.341189e-01 0.873 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 1.341189e-01 0.873 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 1.341189e-01 0.873 0 0
Removal of the Flap Intermediate R-HSA-69166 1.002564e-01 0.999 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.157991e-01 0.936 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 9.907361e-02 1.004 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 1.801145e-01 0.744 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 1.497405e-01 0.825 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.253535e-01 0.902 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.253535e-01 0.902 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.679807e-01 0.775 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 9.853645e-02 1.006 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.082903e-01 0.965 0 0
Deadenylation of mRNA R-HSA-429947 1.699882e-01 0.770 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.208063e-02 1.036 0 0
MET promotes cell motility R-HSA-8875878 1.521170e-01 0.818 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.347145e-01 0.871 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.442988e-01 0.841 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.154629e-01 0.938 0 0
FOXO-mediated transcription R-HSA-9614085 1.227454e-01 0.911 0 0
Integrin signaling R-HSA-354192 1.820819e-01 0.740 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 9.994553e-02 1.000 0 0
Processive synthesis on the lagging strand R-HSA-69183 1.157991e-01 0.936 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 9.907361e-02 1.004 0 0
Integration of provirus R-HSA-162592 1.801145e-01 0.744 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.256911e-01 0.901 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.128944e-01 0.947 0 0
Regulation of the apoptosome activity R-HSA-9627069 1.341189e-01 0.873 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.157991e-01 0.936 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 1.801145e-01 0.744 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.185389e-01 0.926 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 1.820819e-01 0.740 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.037140e-01 0.984 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.486661e-01 0.828 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 1.486661e-01 0.828 0 0
Formation of apoptosome R-HSA-111458 1.341189e-01 0.873 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 9.477716e-02 1.023 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.037140e-01 0.984 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 1.199568e-01 0.921 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 1.055475e-01 0.977 0 0
Degradation of CRY and PER proteins R-HSA-9932298 1.088439e-01 0.963 0 0
Generation of second messenger molecules R-HSA-202433 1.766918e-01 0.753 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 1.199568e-01 0.921 0 0
Dopamine receptors R-HSA-390651 1.161075e-01 0.935 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 1.641984e-01 0.785 0 0
ER-Phagosome pathway R-HSA-1236974 1.019550e-01 0.992 0 0
Developmental Cell Lineages R-HSA-9734767 1.245165e-01 0.905 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 9.477716e-02 1.023 1 1
TBC/RABGAPs R-HSA-8854214 1.278890e-01 0.893 0 0
Degradation of CDH1 R-HSA-9766229 1.080512e-01 0.966 0 0
Activation and oligomerization of BAK protein R-HSA-111452 1.764552e-01 0.753 0 0
Adrenoceptors R-HSA-390696 9.310143e-02 1.031 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.128944e-01 0.947 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 1.827671e-01 0.738 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.994553e-02 1.000 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.994553e-02 1.000 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 1.185389e-01 0.926 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 1.185389e-01 0.926 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.254734e-01 0.901 0 0
Ion homeostasis R-HSA-5578775 1.750156e-01 0.757 0 0
Myogenesis R-HSA-525793 9.477716e-02 1.023 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 1.288830e-01 0.890 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.827671e-01 0.738 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 1.088439e-01 0.963 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 1.088439e-01 0.963 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.729413e-02 1.012 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 1.486661e-01 0.828 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 1.278890e-01 0.893 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.169227e-01 0.932 0 0
Interleukin-1 signaling R-HSA-9020702 1.359714e-01 0.867 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.133849e-01 0.945 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.544657e-01 0.811 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 9.994553e-02 1.000 0 0
Opioid Signalling R-HSA-111885 1.007363e-01 0.997 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 1.764552e-01 0.753 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.764552e-01 0.753 0 0
Unwinding of DNA R-HSA-176974 1.128944e-01 0.947 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 1.128944e-01 0.947 0 0
Proton/oligopeptide cotransporters R-HSA-427975 1.827671e-01 0.738 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 1.827671e-01 0.738 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.002564e-01 0.999 0 0
Bicarbonate transporters R-HSA-425381 1.565881e-01 0.805 0 0
Protein hydroxylation R-HSA-9629569 9.907361e-02 1.004 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.253535e-01 0.902 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 1.679807e-01 0.775 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 1.292696e-01 0.889 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 1.404679e-01 0.852 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 1.485360e-01 0.828 0 0
Mitophagy R-HSA-5205647 1.082903e-01 0.965 0 0
Co-stimulation by CD28 R-HSA-389356 1.822935e-01 0.739 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.433994e-01 0.843 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 1.485360e-01 0.828 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 1.485360e-01 0.828 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.341189e-01 0.873 0 0
PECAM1 interactions R-HSA-210990 1.565881e-01 0.805 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 9.477716e-02 1.023 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 1.641984e-01 0.785 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.853645e-02 1.006 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 1.082903e-01 0.965 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.820819e-01 0.740 0 0
Hedgehog ligand biogenesis R-HSA-5358346 1.254734e-01 0.901 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 1.255549e-01 0.901 0 0
Signaling by FGFR in disease R-HSA-1226099 1.795666e-01 0.746 0 0
Signaling by Hedgehog R-HSA-5358351 1.826796e-01 0.738 0 0
Signal transduction by L1 R-HSA-445144 9.907361e-02 1.004 0 0
Regulation of pyruvate metabolism R-HSA-9861718 1.594310e-01 0.797 0 0
Disease R-HSA-1643685 1.110552e-01 0.954 1 0
Signaling by NOTCH4 R-HSA-9013694 1.084449e-01 0.965 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.288830e-01 0.890 0 0
Immune System R-HSA-168256 1.229707e-01 0.910 1 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 1.118395e-01 0.951 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.678850e-01 0.775 0 0
Gluconeogenesis R-HSA-70263 1.822935e-01 0.739 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 1.118395e-01 0.951 0 0
Syndecan interactions R-HSA-3000170 1.544713e-01 0.811 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 1.827671e-01 0.738 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.750156e-01 0.757 0 0
Signaling by NOTCH3 R-HSA-9012852 1.644599e-01 0.784 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.091110e-01 0.962 0 0
G1/S-Specific Transcription R-HSA-69205 1.292696e-01 0.889 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.497405e-01 0.825 0 0
Inositol phosphate metabolism R-HSA-1483249 1.573475e-01 0.803 0 0
Plasma lipoprotein clearance R-HSA-8964043 1.641984e-01 0.785 0 0
Regulation of BACH1 activity R-HSA-9708530 1.323194e-01 0.878 0 0
Glycogen storage diseases R-HSA-3229121 1.679807e-01 0.775 0 0
GAB1 signalosome R-HSA-180292 1.869547e-01 0.728 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 1.869547e-01 0.728 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 1.869547e-01 0.728 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.879174e-01 0.726 0 0
Circadian clock R-HSA-9909396 1.988966e-01 0.701 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 2.026979e-01 0.693 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 2.026979e-01 0.693 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 2.026979e-01 0.693 0 0
Suppression of phagosomal maturation R-HSA-9637687 2.026979e-01 0.693 0 0
Signaling by FGFR1 in disease R-HSA-5655302 2.028259e-01 0.693 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 2.045139e-01 0.689 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.045139e-01 0.689 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 2.062357e-01 0.686 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.065752e-01 0.685 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.065752e-01 0.685 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 2.065752e-01 0.685 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.065752e-01 0.685 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 2.065752e-01 0.685 0 0
Organelle biogenesis and maintenance R-HSA-1852241 2.111639e-01 0.675 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 2.114821e-01 0.675 0 0
Gap junction assembly R-HSA-190861 2.114821e-01 0.675 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 2.164191e-01 0.665 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 2.164191e-01 0.665 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.178471e-01 0.662 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 2.178471e-01 0.662 0 0
CREB phosphorylation R-HSA-199920 2.178471e-01 0.662 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 2.184037e-01 0.661 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 2.197882e-01 0.658 0 0
Cristae formation R-HSA-8949613 2.197882e-01 0.658 0 0
Platelet degranulation R-HSA-114608 2.247664e-01 0.648 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 2.267542e-01 0.644 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.267542e-01 0.644 0 0
Signaling by NODAL R-HSA-1181150 2.267542e-01 0.644 0 0
Glycogen synthesis R-HSA-3322077 2.267542e-01 0.644 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 2.267663e-01 0.644 0 0
Signalling to ERKs R-HSA-187687 2.267663e-01 0.644 0 0
Pyruvate metabolism R-HSA-70268 2.283677e-01 0.641 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 2.296085e-01 0.639 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 2.296085e-01 0.639 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 2.296085e-01 0.639 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.318401e-01 0.635 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 2.318401e-01 0.635 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.329765e-01 0.633 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.407922e-01 0.618 0 0
RET signaling R-HSA-8853659 2.423921e-01 0.615 0 0
Hedgehog 'on' state R-HSA-5632684 2.427370e-01 0.615 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 2.441899e-01 0.612 0 0
Netrin-1 signaling R-HSA-373752 2.445312e-01 0.612 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.449146e-01 0.611 0 0
Early Phase of HIV Life Cycle R-HSA-162594 2.474039e-01 0.607 0 0
Lagging Strand Synthesis R-HSA-69186 2.474039e-01 0.607 0 0
Basigin interactions R-HSA-210991 2.474039e-01 0.607 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 2.474039e-01 0.607 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 2.526451e-01 0.597 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.526451e-01 0.597 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 2.526451e-01 0.597 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5660686 2.526451e-01 0.597 0 0
TRAF3 deficiency - HSE R-HSA-5602571 2.526451e-01 0.597 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.526451e-01 0.597 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 2.526451e-01 0.597 0 0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 2.526451e-01 0.597 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 2.526451e-01 0.597 0 0
IKBKB deficiency causes SCID R-HSA-5602636 2.526451e-01 0.597 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5619101 2.526451e-01 0.597 0 0
Nef mediated downregulation of CD28 cell surface expression R-HSA-164939 2.526451e-01 0.597 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 2.526451e-01 0.597 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 2.534335e-01 0.596 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 2.534335e-01 0.596 0 0
SOS-mediated signalling R-HSA-112412 2.534335e-01 0.596 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 2.534335e-01 0.596 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 2.534335e-01 0.596 0 0
CHL1 interactions R-HSA-447041 2.534335e-01 0.596 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 2.534335e-01 0.596 0 0
SLC-mediated transport of oligopeptides R-HSA-9959399 2.534335e-01 0.596 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 2.534335e-01 0.596 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 2.542170e-01 0.595 0 0
Signaling by Erythropoietin R-HSA-9006335 2.551749e-01 0.593 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 2.551749e-01 0.593 0 0
Platelet calcium homeostasis R-HSA-418360 2.551749e-01 0.593 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 2.551749e-01 0.593 0 0
Retrograde neurotrophin signalling R-HSA-177504 2.552286e-01 0.593 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.552286e-01 0.593 0 0
Fanconi Anemia Pathway R-HSA-6783310 2.589973e-01 0.587 0 0
Signaling by NTRKs R-HSA-166520 2.662198e-01 0.575 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 2.684378e-01 0.571 0 0
Insulin receptor signalling cascade R-HSA-74751 2.691166e-01 0.570 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 2.733640e-01 0.563 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 2.733640e-01 0.563 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 2.737005e-01 0.563 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 2.745221e-01 0.561 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 2.745221e-01 0.561 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 2.779902e-01 0.556 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 2.812144e-01 0.551 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 2.812144e-01 0.551 0 0
Cellular response to hypoxia R-HSA-1234174 2.818574e-01 0.550 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 2.846749e-01 0.546 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 2.854649e-01 0.544 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 2.891327e-01 0.539 0 0
phospho-PLA2 pathway R-HSA-111995 2.891327e-01 0.539 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 2.891327e-01 0.539 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 2.891327e-01 0.539 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 2.891327e-01 0.539 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 2.891327e-01 0.539 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 2.891327e-01 0.539 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 2.891327e-01 0.539 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 2.909521e-01 0.536 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 2.909521e-01 0.536 0 0
Downstream signal transduction R-HSA-186763 2.918123e-01 0.535 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 2.918123e-01 0.535 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.037086e-01 0.518 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 3.045797e-01 0.516 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 3.074173e-01 0.512 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 3.074173e-01 0.512 0 0
Phosphorylation of the APC/C R-HSA-176412 3.074173e-01 0.512 0 0
Killing mechanisms R-HSA-9664420 3.074173e-01 0.512 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 3.074173e-01 0.512 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 3.074173e-01 0.512 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 3.074173e-01 0.512 0 0
HIV Transcription Elongation R-HSA-167169 3.075760e-01 0.512 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.075760e-01 0.512 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.075760e-01 0.512 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.113236e-01 0.507 0 0
Growth hormone receptor signaling R-HSA-982772 3.113236e-01 0.507 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.136854e-01 0.504 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.163382e-01 0.500 1 1
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.189581e-01 0.496 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.209831e-01 0.494 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 3.217904e-01 0.492 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 3.217904e-01 0.492 0 0
Defective PAPSS2 causes SEMD-PA R-HSA-3560796 3.217904e-01 0.492 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 3.217904e-01 0.492 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 3.217904e-01 0.492 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 3.217904e-01 0.492 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 3.217904e-01 0.492 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.217904e-01 0.492 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 3.217904e-01 0.492 0 0
mRNA Editing: A to I Conversion R-HSA-75064 3.217904e-01 0.492 0 0
Regulation of cortical dendrite branching R-HSA-8985801 3.217904e-01 0.492 0 0
C6 deamination of adenosine R-HSA-75102 3.217904e-01 0.492 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 3.217904e-01 0.492 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 3.217904e-01 0.492 0 0
Lipophagy R-HSA-9613354 3.246196e-01 0.489 0 0
WNT mediated activation of DVL R-HSA-201688 3.246196e-01 0.489 0 0
Calcineurin activates NFAT R-HSA-2025928 3.246196e-01 0.489 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.246196e-01 0.489 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 3.246196e-01 0.489 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.246196e-01 0.489 0 0
Nuclear RNA decay R-HSA-9930044 3.292777e-01 0.482 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.292777e-01 0.482 0 0
Regulation of necroptotic cell death R-HSA-5675482 3.292777e-01 0.482 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.292777e-01 0.482 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.292777e-01 0.482 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 3.330157e-01 0.478 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 3.337000e-01 0.477 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 3.337000e-01 0.477 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 3.337000e-01 0.477 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 3.337000e-01 0.477 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.337000e-01 0.477 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 3.337000e-01 0.477 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 3.337000e-01 0.477 1 1
Sensory processing of sound R-HSA-9659379 3.396292e-01 0.469 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 3.476455e-01 0.459 0 0
Effects of PIP2 hydrolysis R-HSA-114508 3.481935e-01 0.458 0 0
Unfolded Protein Response (UPR) R-HSA-381119 3.491468e-01 0.457 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.547734e-01 0.450 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 3.547734e-01 0.450 0 0
Interleukin-7 signaling R-HSA-1266695 3.547734e-01 0.450 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 3.561904e-01 0.448 0 0
Binding and entry of HIV virion R-HSA-173107 3.596281e-01 0.444 0 0
MAPK3 (ERK1) activation R-HSA-110056 3.596281e-01 0.444 0 0
2-LTR circle formation R-HSA-164843 3.596281e-01 0.444 0 0
DNA replication initiation R-HSA-68952 3.596281e-01 0.444 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.596281e-01 0.444 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 3.596281e-01 0.444 0 0
Signaling by Leptin R-HSA-2586552 3.596281e-01 0.444 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 3.599374e-01 0.444 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 3.599374e-01 0.444 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 3.599374e-01 0.444 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 3.599374e-01 0.444 0 0
Interferon gamma signaling R-HSA-877300 3.610817e-01 0.442 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 3.671664e-01 0.435 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 3.671664e-01 0.435 0 0
Signaling by NOTCH2 R-HSA-1980145 3.671664e-01 0.435 0 0
Downstream TCR signaling R-HSA-202424 3.680441e-01 0.434 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 3.845421e-01 0.415 0 0
PLC-gamma1 signalling R-HSA-167021 3.845421e-01 0.415 0 0
Axonal growth stimulation R-HSA-209563 3.845421e-01 0.415 0 0
TFAP2 (AP-2) family regulates transcription of other transcription factors R-HSA-8866906 3.845421e-01 0.415 0 0
Defective HPRT1 disrupts guanine and hypoxanthine salvage R-HSA-9734281 3.845421e-01 0.415 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 3.845421e-01 0.415 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.845421e-01 0.415 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.845421e-01 0.415 0 0
MET activates STAT3 R-HSA-8875791 3.845421e-01 0.415 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 3.845421e-01 0.415 0 0
Activation of BMF and translocation to mitochondria R-HSA-139910 3.845421e-01 0.415 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 3.860161e-01 0.413 0 0
Presynaptic function of Kainate receptors R-HSA-500657 3.860161e-01 0.413 0 0
Polo-like kinase mediated events R-HSA-156711 3.860161e-01 0.413 0 0
Apoptotic factor-mediated response R-HSA-111471 3.860161e-01 0.413 0 0
Mismatch Repair R-HSA-5358508 3.860161e-01 0.413 0 0
Interleukin-1 family signaling R-HSA-446652 3.877618e-01 0.411 0 0
Ca2+ pathway R-HSA-4086398 3.881591e-01 0.411 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 3.904980e-01 0.408 0 0
IRE1alpha activates chaperones R-HSA-381070 3.922929e-01 0.406 0 0
Proteasome assembly R-HSA-9907900 3.923443e-01 0.406 0 0
Amine ligand-binding receptors R-HSA-375280 3.923443e-01 0.406 0 0
Chylomicron assembly R-HSA-8963888 3.939431e-01 0.405 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 3.939431e-01 0.405 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 3.968790e-01 0.401 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 3.982094e-01 0.400 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 3.982094e-01 0.400 0 0
Signaling by BMP R-HSA-201451 3.982094e-01 0.400 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.982094e-01 0.400 0 0
IGF1R signaling cascade R-HSA-2428924 3.995703e-01 0.398 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 4.093872e-01 0.388 0 0
Specification of the neural plate border R-HSA-9834899 4.118346e-01 0.385 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 4.140635e-01 0.383 0 0
PI Metabolism R-HSA-1483255 4.169089e-01 0.380 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 4.197606e-01 0.377 0 0
Formation of the Early Elongation Complex R-HSA-113418 4.197606e-01 0.377 0 0
HIV elongation arrest and recovery R-HSA-167287 4.197606e-01 0.377 0 0
Pausing and recovery of HIV elongation R-HSA-167290 4.197606e-01 0.377 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.197606e-01 0.377 0 0
Signaling by TGFBR3 R-HSA-9839373 4.263847e-01 0.370 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.273934e-01 0.369 0 0
ERKs are inactivated R-HSA-202670 4.273934e-01 0.369 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 4.273934e-01 0.369 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.273934e-01 0.369 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 4.273934e-01 0.369 0 0
Signaling by NOTCH1 R-HSA-1980143 4.288914e-01 0.368 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 4.289578e-01 0.368 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 4.373028e-01 0.359 0 0
Co-inhibition by CTLA4 R-HSA-389513 4.373028e-01 0.359 0 0
Creatine metabolism R-HSA-71288 4.373028e-01 0.359 0 0
mRNA Capping R-HSA-72086 4.411237e-01 0.355 0 0
HCN channels R-HSA-1296061 4.414910e-01 0.355 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 4.414910e-01 0.355 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 4.414910e-01 0.355 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 4.414910e-01 0.355 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.414910e-01 0.355 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 4.414910e-01 0.355 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 4.414910e-01 0.355 0 0
Regulation of gap junction activity R-HSA-191650 4.414910e-01 0.355 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 4.414910e-01 0.355 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 4.414910e-01 0.355 0 0
NADE modulates death signalling R-HSA-205025 4.414910e-01 0.355 0 0
Interleukin-38 signaling R-HSA-9007892 4.414910e-01 0.355 0 0
XBP1(S) activates chaperone genes R-HSA-381038 4.417632e-01 0.355 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 4.427362e-01 0.354 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 4.433074e-01 0.353 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 4.440139e-01 0.353 0 0
Transcription of the HIV genome R-HSA-167172 4.573719e-01 0.340 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 4.598453e-01 0.337 0 0
Repression of WNT target genes R-HSA-4641265 4.598453e-01 0.337 0 0
Leading Strand Synthesis R-HSA-69109 4.598453e-01 0.337 0 0
Polymerase switching R-HSA-69091 4.598453e-01 0.337 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.598453e-01 0.337 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 4.598453e-01 0.337 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.598453e-01 0.337 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.613447e-01 0.336 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 4.613447e-01 0.336 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 4.622467e-01 0.335 0 0
ERK/MAPK targets R-HSA-198753 4.623416e-01 0.335 0 0
Potential therapeutics for SARS R-HSA-9679191 4.645795e-01 0.333 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 4.664446e-01 0.331 0 0
Transmission across Chemical Synapses R-HSA-112315 4.743499e-01 0.324 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 4.797670e-01 0.319 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 4.797670e-01 0.319 0 0
Glycogen metabolism R-HSA-8982491 4.797670e-01 0.319 0 0
Cargo concentration in the ER R-HSA-5694530 4.830827e-01 0.316 0 0
Trafficking of AMPA receptors R-HSA-399719 4.830827e-01 0.316 0 0
RAB geranylgeranylation R-HSA-8873719 4.893996e-01 0.310 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 4.893996e-01 0.310 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 4.893996e-01 0.310 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 4.893996e-01 0.310 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 4.893996e-01 0.310 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 4.893996e-01 0.310 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 4.893996e-01 0.310 0 0
Formation of axial mesoderm R-HSA-9796292 4.911972e-01 0.309 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 4.911972e-01 0.309 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 4.911972e-01 0.309 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 4.911972e-01 0.309 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 4.931734e-01 0.307 0 0
G2 Phase R-HSA-68911 4.931734e-01 0.307 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 4.931734e-01 0.307 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.931734e-01 0.307 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 4.931734e-01 0.307 0 0
Reelin signalling pathway R-HSA-8866376 4.931734e-01 0.307 0 0
Suppression of autophagy R-HSA-9636569 4.931734e-01 0.307 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.931734e-01 0.307 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 4.931734e-01 0.307 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 4.931734e-01 0.307 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 4.931734e-01 0.307 0 0
PI3K Cascade R-HSA-109704 4.933524e-01 0.307 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.933524e-01 0.307 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.979709e-01 0.303 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.045205e-01 0.297 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 5.108669e-01 0.292 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 5.108669e-01 0.292 0 0
ABC-family proteins mediated transport R-HSA-382556 5.131924e-01 0.290 0 0
Translation of Structural Proteins R-HSA-9683701 5.159271e-01 0.287 0 0
Disorders of transmembrane transporters R-HSA-5619115 5.201018e-01 0.284 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 5.213749e-01 0.283 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 5.213749e-01 0.283 0 0
Signaling by FGFR4 in disease R-HSA-5655291 5.213749e-01 0.283 0 0
Regulation of KIT signaling R-HSA-1433559 5.213749e-01 0.283 0 0
Physiological factors R-HSA-5578768 5.213749e-01 0.283 0 0
Malate-aspartate shuttle R-HSA-9856872 5.213749e-01 0.283 0 0
Zinc transporters R-HSA-435354 5.213749e-01 0.283 0 0
Hemostasis R-HSA-109582 5.224823e-01 0.282 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 5.237280e-01 0.281 0 0
Neurexins and neuroligins R-HSA-6794361 5.258671e-01 0.279 0 0
SLC transporter disorders R-HSA-5619102 5.278035e-01 0.278 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 5.294428e-01 0.276 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 5.299093e-01 0.276 0 0
Plus-strand DNA synthesis R-HSA-164525 5.400761e-01 0.268 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 5.400761e-01 0.268 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 5.400761e-01 0.268 0 0
PKB-mediated events R-HSA-109703 5.400761e-01 0.268 0 0
PDE3B signalling R-HSA-165160 5.400761e-01 0.268 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 5.400761e-01 0.268 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 5.400761e-01 0.268 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 5.400761e-01 0.268 0 0
Signaling by MAPK mutants R-HSA-9652817 5.400761e-01 0.268 0 0
Loss-of-function mutations in DBT cause MSUD2 R-HSA-9865113 5.400761e-01 0.268 0 0
Loss-of-function mutations in DLD cause MSUD3/DLDD R-HSA-9907570 5.400761e-01 0.268 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 5.400761e-01 0.268 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 5.400761e-01 0.268 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 5.400761e-01 0.268 0 0
Pentose phosphate pathway disease R-HSA-6791465 5.400761e-01 0.268 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 5.400761e-01 0.268 0 0
Phosphorylation of Emi1 R-HSA-176417 5.400761e-01 0.268 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.400761e-01 0.268 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 5.400761e-01 0.268 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 5.400761e-01 0.268 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 5.400761e-01 0.268 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 5.400761e-01 0.268 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 5.418045e-01 0.266 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 5.434659e-01 0.265 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 5.434659e-01 0.265 0 0
Protein-protein interactions at synapses R-HSA-6794362 5.482675e-01 0.261 0 0
Ion transport by P-type ATPases R-HSA-936837 5.489064e-01 0.261 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 5.503273e-01 0.259 0 0
G beta:gamma signalling through BTK R-HSA-8964315 5.503273e-01 0.259 0 0
Signaling by Activin R-HSA-1502540 5.503273e-01 0.259 0 0
Signaling by SCF-KIT R-HSA-1433557 5.509917e-01 0.259 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 5.569764e-01 0.254 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 5.569764e-01 0.254 1 0
CD209 (DC-SIGN) signaling R-HSA-5621575 5.569764e-01 0.254 0 0
Plasma lipoprotein assembly R-HSA-8963898 5.569764e-01 0.254 0 0
Calnexin/calreticulin cycle R-HSA-901042 5.627734e-01 0.250 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 5.627734e-01 0.250 0 0
MITF-M-dependent gene expression R-HSA-9856651 5.640170e-01 0.249 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 5.662756e-01 0.247 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.780226e-01 0.238 0 0
Attachment and Entry R-HSA-9678110 5.780226e-01 0.238 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.780226e-01 0.238 0 0
Differentiation of T cells R-HSA-9945266 5.780226e-01 0.238 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 5.780226e-01 0.238 0 0
Tight junction interactions R-HSA-420029 5.790276e-01 0.237 0 0
TGFBR3 expression R-HSA-9839394 5.790276e-01 0.237 0 0
PERK regulates gene expression R-HSA-381042 5.816253e-01 0.235 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.826408e-01 0.235 0 0
STAT5 Activation R-HSA-9645135 5.826408e-01 0.235 0 0
G2/M DNA replication checkpoint R-HSA-69478 5.826408e-01 0.235 0 0
Uncoating of the HIV Virion R-HSA-162585 5.826408e-01 0.235 0 0
Autointegration results in viral DNA circles R-HSA-177539 5.826408e-01 0.235 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 5.826408e-01 0.235 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 5.826408e-01 0.235 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 5.826408e-01 0.235 0 0
MET Receptor Activation R-HSA-6806942 5.826408e-01 0.235 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 5.826408e-01 0.235 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.826408e-01 0.235 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 5.826408e-01 0.235 0 0
HDL clearance R-HSA-8964011 5.826408e-01 0.235 0 0
VLDL assembly R-HSA-8866423 5.826408e-01 0.235 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 5.847759e-01 0.233 0 0
ABC transporter disorders R-HSA-5619084 5.948706e-01 0.226 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 6.000002e-01 0.222 0 0
GPVI-mediated activation cascade R-HSA-114604 6.000002e-01 0.222 0 0
FGFR2 mutant receptor activation R-HSA-1839126 6.000002e-01 0.222 0 0
MET activates PTK2 signaling R-HSA-8874081 6.003730e-01 0.222 0 0
Diseases of DNA repair R-HSA-9675135 6.011407e-01 0.221 0 0
IRS-mediated signalling R-HSA-112399 6.030063e-01 0.220 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 6.044457e-01 0.219 0 0
Disorders of Developmental Biology R-HSA-9675151 6.044457e-01 0.219 0 0
Regulated Necrosis R-HSA-5218859 6.052479e-01 0.218 0 0
Neuronal System R-HSA-112316 6.056927e-01 0.218 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 6.076903e-01 0.216 0 0
Parasitic Infection Pathways R-HSA-9824443 6.153168e-01 0.211 0 0
Leishmania infection R-HSA-9658195 6.153168e-01 0.211 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 6.209934e-01 0.207 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 6.209934e-01 0.207 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 6.209934e-01 0.207 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 6.209934e-01 0.207 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 6.209934e-01 0.207 0 0
Insulin processing R-HSA-264876 6.209934e-01 0.207 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 6.212686e-01 0.207 0 0
TRIF-mediated programmed cell death R-HSA-2562578 6.212686e-01 0.207 0 0
Recycling of eIF2:GDP R-HSA-72731 6.212686e-01 0.207 0 0
DAG1 core M1 glycosylations R-HSA-8932506 6.212686e-01 0.207 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 6.212686e-01 0.207 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 6.212686e-01 0.207 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.212686e-01 0.207 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 6.212686e-01 0.207 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 6.212686e-01 0.207 0 0
Ca2+ activated K+ channels R-HSA-1296052 6.212686e-01 0.207 0 0
LDL remodeling R-HSA-8964041 6.212686e-01 0.207 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.212686e-01 0.207 0 0
Integration of energy metabolism R-HSA-163685 6.232190e-01 0.205 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 6.295946e-01 0.201 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 6.295946e-01 0.201 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 6.295946e-01 0.201 0 0
Specification of primordial germ cells R-HSA-9827857 6.295946e-01 0.201 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 6.318794e-01 0.199 0 0
Regulation of beta-cell development R-HSA-186712 6.318794e-01 0.199 0 0
GPER1 signaling R-HSA-9634597 6.327416e-01 0.199 0 0
Intraflagellar transport R-HSA-5620924 6.327416e-01 0.199 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 6.408757e-01 0.193 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 6.479544e-01 0.188 0 0
Pentose phosphate pathway R-HSA-71336 6.521021e-01 0.186 0 0
RAS processing R-HSA-9648002 6.521021e-01 0.186 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 6.534790e-01 0.185 0 0
PKA activation R-HSA-163615 6.534790e-01 0.185 0 0
PKA activation in glucagon signalling R-HSA-164378 6.534790e-01 0.185 0 0
Nephron development R-HSA-9831926 6.534790e-01 0.185 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 6.534790e-01 0.185 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.534790e-01 0.185 0 0
Reverse Transcription of HIV RNA R-HSA-162589 6.563234e-01 0.183 0 0
Minus-strand DNA synthesis R-HSA-164516 6.563234e-01 0.183 0 0
DAG1 core M2 glycosylations R-HSA-8932504 6.563234e-01 0.183 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 6.563234e-01 0.183 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.563234e-01 0.183 0 0
Co-stimulation by ICOS R-HSA-9927354 6.563234e-01 0.183 0 0
FGFR1b ligand binding and activation R-HSA-190370 6.563234e-01 0.183 0 0
Nucleotide salvage defects R-HSA-9734207 6.563234e-01 0.183 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.563234e-01 0.183 0 0
Sodium/Proton exchangers R-HSA-425986 6.563234e-01 0.183 0 0
Interleukin-23 signaling R-HSA-9020933 6.563234e-01 0.183 0 0
Signaling by Insulin receptor R-HSA-74752 6.565471e-01 0.183 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 6.576592e-01 0.182 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 6.576592e-01 0.182 0 0
DARPP-32 events R-HSA-180024 6.600119e-01 0.180 0 0
Glucagon-type ligand receptors R-HSA-420092 6.600119e-01 0.180 0 0
Parasite infection R-HSA-9664407 6.602597e-01 0.180 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.602597e-01 0.180 0 0
Leishmania phagocytosis R-HSA-9664417 6.602597e-01 0.180 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 6.619912e-01 0.179 0 0
Cardiac conduction R-HSA-5576891 6.684043e-01 0.175 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 6.684243e-01 0.175 0 0
Diseases of Immune System R-HSA-5260271 6.684243e-01 0.175 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 6.684243e-01 0.175 0 0
Signaling by PDGF R-HSA-186797 6.727931e-01 0.172 0 0
Heme signaling R-HSA-9707616 6.727931e-01 0.172 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 6.761175e-01 0.170 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 6.761175e-01 0.170 0 0
The NLRP3 inflammasome R-HSA-844456 6.761175e-01 0.170 0 0
STING mediated induction of host immune responses R-HSA-1834941 6.761175e-01 0.170 0 0
Mitochondrial protein degradation R-HSA-9837999 6.784714e-01 0.168 0 0
MAPK1 (ERK2) activation R-HSA-112411 6.881354e-01 0.162 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.881354e-01 0.162 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 6.881354e-01 0.162 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 6.881354e-01 0.162 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 6.881354e-01 0.162 0 0
mRNA Editing R-HSA-75072 6.881354e-01 0.162 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.881354e-01 0.162 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 6.881354e-01 0.162 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 6.881354e-01 0.162 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 6.881354e-01 0.162 0 0
Regulated proteolysis of p75NTR R-HSA-193692 6.881354e-01 0.162 0 0
Interleukin-1 processing R-HSA-448706 6.881354e-01 0.162 0 0
Cellular response to mitochondrial stress R-HSA-9840373 6.881354e-01 0.162 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 6.881354e-01 0.162 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 6.881354e-01 0.162 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 6.911433e-01 0.160 0 0
Molecules associated with elastic fibres R-HSA-2129379 6.960383e-01 0.157 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 6.975359e-01 0.156 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 6.975359e-01 0.156 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 6.975359e-01 0.156 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 6.975359e-01 0.156 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 6.975359e-01 0.156 0 0
Formation of definitive endoderm R-HSA-9823730 6.975359e-01 0.156 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 6.994640e-01 0.155 0 0
HIV Transcription Initiation R-HSA-167161 6.994640e-01 0.155 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 6.994640e-01 0.155 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 6.994640e-01 0.155 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 6.994640e-01 0.155 0 0
Amino acids regulate mTORC1 R-HSA-9639288 7.047063e-01 0.152 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.129346e-01 0.147 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 7.129346e-01 0.147 0 0
OADH complex synthesizes glutaryl-CoA from 2-OA R-HSA-9858328 7.170045e-01 0.144 0 0
Regulation of CDH11 function R-HSA-9762292 7.170045e-01 0.144 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 7.170045e-01 0.144 0 0
Receptor Mediated Mitophagy R-HSA-8934903 7.170045e-01 0.144 0 0
Sperm Motility And Taxes R-HSA-1300642 7.170045e-01 0.144 0 0
G-protein activation R-HSA-202040 7.177662e-01 0.144 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 7.177662e-01 0.144 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 7.177662e-01 0.144 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 7.177662e-01 0.144 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 7.177662e-01 0.144 0 0
Mitochondrial biogenesis R-HSA-1592230 7.240769e-01 0.140 0 0
Stimuli-sensing channels R-HSA-2672351 7.264004e-01 0.139 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 7.283559e-01 0.138 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 7.290961e-01 0.137 0 0
Regulation of insulin secretion R-HSA-422356 7.294326e-01 0.137 0 0
Attachment and Entry R-HSA-9694614 7.368448e-01 0.133 0 0
Mitochondrial calcium ion transport R-HSA-8949215 7.368448e-01 0.133 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 7.368448e-01 0.133 0 0
Serine metabolism R-HSA-977347 7.368448e-01 0.133 0 0
DAG1 core M3 glycosylations R-HSA-8932505 7.432027e-01 0.129 0 0
LGI-ADAM interactions R-HSA-5682910 7.432027e-01 0.129 0 0
vRNP Assembly R-HSA-192905 7.432027e-01 0.129 0 0
vRNA Synthesis R-HSA-192814 7.432027e-01 0.129 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 7.432027e-01 0.129 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 7.432027e-01 0.129 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 7.432027e-01 0.129 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 7.432027e-01 0.129 0 0
Transport of RCbl within the body R-HSA-9758890 7.432027e-01 0.129 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.445338e-01 0.128 0 0
Miscellaneous transport and binding events R-HSA-5223345 7.445338e-01 0.128 0 0
Notch-HLH transcription pathway R-HSA-350054 7.548114e-01 0.122 0 0
LDL clearance R-HSA-8964038 7.548114e-01 0.122 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 7.548114e-01 0.122 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 7.551190e-01 0.122 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 7.551190e-01 0.122 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 7.551190e-01 0.122 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 7.563422e-01 0.121 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 7.581909e-01 0.120 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.590385e-01 0.120 0 0
Signal amplification R-HSA-392518 7.592612e-01 0.120 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 7.592612e-01 0.120 0 0
eNOS activation R-HSA-203615 7.592612e-01 0.120 0 0
Hyaluronan metabolism R-HSA-2142845 7.592612e-01 0.120 0 0
Adipogenesis R-HSA-9843745 7.631249e-01 0.117 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 7.662143e-01 0.116 0 0
COPII-mediated vesicle transport R-HSA-204005 7.668918e-01 0.115 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 7.669771e-01 0.115 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 7.669771e-01 0.115 0 0
Plasmalogen biosynthesis R-HSA-75896 7.669771e-01 0.115 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 7.669771e-01 0.115 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 7.669771e-01 0.115 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 7.669771e-01 0.115 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 7.669771e-01 0.115 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 7.669771e-01 0.115 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 7.669771e-01 0.115 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 7.717084e-01 0.113 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 7.717084e-01 0.113 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.717084e-01 0.113 0 0
Peroxisomal protein import R-HSA-9033241 7.772682e-01 0.109 0 0
Extension of Telomeres R-HSA-180786 7.772682e-01 0.109 0 0
Triglyceride metabolism R-HSA-8979227 7.772682e-01 0.109 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 7.772682e-01 0.109 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 7.797997e-01 0.108 0 0
Formation of the cornified envelope R-HSA-6809371 7.818010e-01 0.107 0 0
Glycosphingolipid transport R-HSA-9845576 7.866483e-01 0.104 0 0
Triglyceride catabolism R-HSA-163560 7.866483e-01 0.104 0 0
Thromboxane signalling through TP receptor R-HSA-428930 7.875799e-01 0.104 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 7.875799e-01 0.104 0 0
MET activates RAS signaling R-HSA-8851805 7.885517e-01 0.103 0 0
Scavenging by Class F Receptors R-HSA-3000484 7.885517e-01 0.103 0 0
Maple Syrup Urine Disease R-HSA-9865114 7.885517e-01 0.103 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 7.885517e-01 0.103 0 0
GRB2 events in EGFR signaling R-HSA-179812 7.885517e-01 0.103 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 7.885517e-01 0.103 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 7.885517e-01 0.103 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 7.885517e-01 0.103 0 0
Signaling by LTK R-HSA-9842663 7.885517e-01 0.103 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 7.885517e-01 0.103 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 7.885517e-01 0.103 0 0
Disorders of Nervous System Development R-HSA-9697154 7.885517e-01 0.103 0 0
Pervasive developmental disorders R-HSA-9005895 7.885517e-01 0.103 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 7.885517e-01 0.103 0 0
Interleukin-15 signaling R-HSA-8983432 7.885517e-01 0.103 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 7.885517e-01 0.103 0 0
OAS antiviral response R-HSA-8983711 7.885517e-01 0.103 0 0
Collagen formation R-HSA-1474290 7.890502e-01 0.103 0 0
Metal ion SLC transporters R-HSA-425410 7.913796e-01 0.102 0 0
Ion channel transport R-HSA-983712 7.925906e-01 0.101 0 0
Interferon alpha/beta signaling R-HSA-909733 8.012539e-01 0.096 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 8.024707e-01 0.096 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 8.024707e-01 0.096 0 0
G protein gated Potassium channels R-HSA-1296059 8.024707e-01 0.096 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 8.024707e-01 0.096 0 0
Acyl chain remodelling of PS R-HSA-1482801 8.024707e-01 0.096 0 0
Laminin interactions R-HSA-3000157 8.024707e-01 0.096 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 8.024707e-01 0.096 0 0
Hyaluronan degradation R-HSA-2160916 8.024707e-01 0.096 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 8.024707e-01 0.096 0 0
Mitochondrial protein import R-HSA-1268020 8.080165e-01 0.093 0 0
OGDH complex synthesizes succinyl-CoA from 2-OG R-HSA-9853506 8.081299e-01 0.093 0 0
PDH complex synthesizes acetyl-CoA from PYR R-HSA-9861559 8.081299e-01 0.093 0 0
Processing of SMDT1 R-HSA-8949664 8.081299e-01 0.093 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 8.081299e-01 0.093 0 0
FGFR1c ligand binding and activation R-HSA-190373 8.081299e-01 0.093 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 8.081299e-01 0.093 0 0
Diseases of nucleotide metabolism R-HSA-9735804 8.081299e-01 0.093 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 8.081299e-01 0.093 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 8.081299e-01 0.093 0 0
CD28 dependent Vav1 pathway R-HSA-389359 8.081299e-01 0.093 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 8.081299e-01 0.093 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 8.081299e-01 0.093 0 0
Maturation of nucleoprotein R-HSA-9683610 8.081299e-01 0.093 0 0
Interleukin-6 signaling R-HSA-1059683 8.081299e-01 0.093 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.081299e-01 0.093 0 0
Metabolism of proteins R-HSA-392499 8.082994e-01 0.092 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.114001e-01 0.091 0 0
Elastic fibre formation R-HSA-1566948 8.114001e-01 0.091 0 0
Iron uptake and transport R-HSA-917937 8.145659e-01 0.089 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 8.164264e-01 0.088 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 8.164264e-01 0.088 0 0
Urea cycle R-HSA-70635 8.164264e-01 0.088 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 8.164264e-01 0.088 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 8.174833e-01 0.088 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 8.174833e-01 0.088 0 0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV R-HSA-9859138 8.258965e-01 0.083 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 8.258965e-01 0.083 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 8.258965e-01 0.083 0 0
Hydrolysis of LPC R-HSA-1483115 8.258965e-01 0.083 0 0
cGMP effects R-HSA-418457 8.258965e-01 0.083 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.258965e-01 0.083 0 0
HDL assembly R-HSA-8963896 8.258965e-01 0.083 0 0
Signal regulatory protein family interactions R-HSA-391160 8.258965e-01 0.083 0 0
Acyl chain remodeling of CL R-HSA-1482798 8.258965e-01 0.083 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 8.258965e-01 0.083 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 8.294925e-01 0.081 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 8.294925e-01 0.081 0 0
Signaling by FGFR3 in disease R-HSA-5655332 8.294925e-01 0.081 0 0
Triglyceride biosynthesis R-HSA-75109 8.294925e-01 0.081 0 0
Maturation of hRSV A proteins R-HSA-9828806 8.294925e-01 0.081 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 8.328756e-01 0.079 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 8.417139e-01 0.075 0 0
Inflammasomes R-HSA-622312 8.417139e-01 0.075 0 0
Pyroptosis R-HSA-5620971 8.417139e-01 0.075 0 0
Erythropoietin activates RAS R-HSA-9027284 8.420188e-01 0.075 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 8.420188e-01 0.075 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 8.420188e-01 0.075 0 0
SHC1 events in EGFR signaling R-HSA-180336 8.420188e-01 0.075 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 8.420188e-01 0.075 0 0
Telomere C-strand synthesis initiation R-HSA-174430 8.420188e-01 0.075 0 0
Transport and metabolism of PAPS R-HSA-174362 8.420188e-01 0.075 0 0
p38MAPK events R-HSA-171007 8.420188e-01 0.075 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 8.420188e-01 0.075 0 0
Other semaphorin interactions R-HSA-416700 8.420188e-01 0.075 0 0
DNA Damage Reversal R-HSA-73942 8.420188e-01 0.075 0 0
Protein localization R-HSA-9609507 8.448812e-01 0.073 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 8.510384e-01 0.070 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 8.531351e-01 0.069 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 8.531351e-01 0.069 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 8.566491e-01 0.067 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 8.566491e-01 0.067 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 8.566491e-01 0.067 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 8.566491e-01 0.067 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 8.566491e-01 0.067 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 8.566491e-01 0.067 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 8.566491e-01 0.067 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 8.566491e-01 0.067 0 0
G alpha (z) signalling events R-HSA-418597 8.592761e-01 0.066 0 0
FCERI mediated NF-kB activation R-HSA-2871837 8.600142e-01 0.065 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.628281e-01 0.064 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.637994e-01 0.064 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 8.637994e-01 0.064 0 0
DAP12 signaling R-HSA-2424491 8.637994e-01 0.064 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 8.637994e-01 0.064 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 8.637994e-01 0.064 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.637994e-01 0.064 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 8.637994e-01 0.064 0 0
Interleukin-37 signaling R-HSA-9008059 8.637994e-01 0.064 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 8.699253e-01 0.061 0 0
Fibronectin matrix formation R-HSA-1566977 8.699253e-01 0.061 0 0
Glycine degradation R-HSA-6783984 8.699253e-01 0.061 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 8.699253e-01 0.061 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 8.699253e-01 0.061 0 0
Coenzyme A biosynthesis R-HSA-196783 8.699253e-01 0.061 0 0
RSV-host interactions R-HSA-9833110 8.736780e-01 0.059 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 8.737490e-01 0.059 0 0
Innate Immune System R-HSA-168249 8.745921e-01 0.058 0 0
tRNA processing R-HSA-72306 8.755903e-01 0.058 0 0
DAP12 interactions R-HSA-2172127 8.796753e-01 0.056 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 8.819726e-01 0.055 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 8.819726e-01 0.055 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 8.819726e-01 0.055 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 8.819726e-01 0.055 0 0
Sulfide oxidation to sulfate R-HSA-1614517 8.819726e-01 0.055 0 0
Choline catabolism R-HSA-6798163 8.819726e-01 0.055 0 0
Uptake and function of anthrax toxins R-HSA-5210891 8.819726e-01 0.055 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.819726e-01 0.055 0 0
Inwardly rectifying K+ channels R-HSA-1296065 8.830248e-01 0.054 0 0
Gastrulation R-HSA-9758941 8.843176e-01 0.053 0 0
Platelet homeostasis R-HSA-418346 8.846410e-01 0.053 0 0
Somitogenesis R-HSA-9824272 8.873884e-01 0.052 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 8.916662e-01 0.050 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 8.916662e-01 0.050 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 8.927902e-01 0.049 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 8.929048e-01 0.049 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 8.929048e-01 0.049 0 0
FGFR1 ligand binding and activation R-HSA-190242 8.929048e-01 0.049 0 0
Platelet sensitization by LDL R-HSA-432142 8.929048e-01 0.049 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 8.931497e-01 0.049 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 8.977685e-01 0.047 0 0
Resolution of D-Loop Structures R-HSA-5693537 8.997110e-01 0.046 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 8.997110e-01 0.046 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.997110e-01 0.046 0 0
Aquaporin-mediated transport R-HSA-445717 9.015166e-01 0.045 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.019205e-01 0.045 0 0
Post-translational protein modification R-HSA-597592 9.024603e-01 0.045 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 9.028250e-01 0.044 0 0
Germ layer formation at gastrulation R-HSA-9754189 9.028250e-01 0.044 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.028250e-01 0.044 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.028250e-01 0.044 0 0
Maturation of nucleoprotein R-HSA-9694631 9.028250e-01 0.044 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 9.028250e-01 0.044 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 9.028250e-01 0.044 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.041227e-01 0.044 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.073493e-01 0.042 0 0
NGF-stimulated transcription R-HSA-9031628 9.079393e-01 0.042 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.118268e-01 0.040 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.118268e-01 0.040 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 9.118268e-01 0.040 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 9.118268e-01 0.040 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.118268e-01 0.040 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.118268e-01 0.040 0 0
Synthesis of Ketone Bodies R-HSA-77111 9.118268e-01 0.040 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.128819e-01 0.040 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.141550e-01 0.039 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.141550e-01 0.039 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.143963e-01 0.039 0 0
Translation of Structural Proteins R-HSA-9694635 9.143963e-01 0.039 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.191604e-01 0.037 0 0
Integrin cell surface interactions R-HSA-216083 9.191604e-01 0.037 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 9.199952e-01 0.036 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 9.199952e-01 0.036 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 9.199952e-01 0.036 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 9.199952e-01 0.036 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.199952e-01 0.036 0 0
Signalling to RAS R-HSA-167044 9.199952e-01 0.036 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.199952e-01 0.036 0 0
RNA Polymerase III Transcription R-HSA-74158 9.206219e-01 0.036 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 9.206219e-01 0.036 0 0
Voltage gated Potassium channels R-HSA-1296072 9.266278e-01 0.033 0 0
Lysine catabolism R-HSA-71064 9.266278e-01 0.033 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 9.274073e-01 0.033 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.274073e-01 0.033 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.274073e-01 0.033 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 9.274073e-01 0.033 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.296678e-01 0.032 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.303656e-01 0.031 0 0
Neddylation R-HSA-8951664 9.305083e-01 0.031 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.334234e-01 0.030 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.341332e-01 0.030 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.341332e-01 0.030 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 9.341332e-01 0.030 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.341332e-01 0.030 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 9.341332e-01 0.030 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 9.341332e-01 0.030 0 0
Signaling by KIT in disease R-HSA-9669938 9.341332e-01 0.030 0 0
Ethanol oxidation R-HSA-71384 9.341332e-01 0.030 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.341332e-01 0.030 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.358213e-01 0.029 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.363134e-01 0.029 0 0
Signaling by ALK R-HSA-201556 9.373750e-01 0.028 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.402362e-01 0.027 0 0
Interleukin receptor SHC signaling R-HSA-912526 9.402362e-01 0.027 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.402362e-01 0.027 0 0
Formation of the ureteric bud R-HSA-9830674 9.402362e-01 0.027 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 9.402362e-01 0.027 0 0
Ketone body metabolism R-HSA-74182 9.402362e-01 0.027 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.457740e-01 0.024 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 9.457740e-01 0.024 0 0
Complex III assembly R-HSA-9865881 9.457740e-01 0.024 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.457740e-01 0.024 0 0
Interleukin-6 family signaling R-HSA-6783589 9.457740e-01 0.024 0 0
Potassium Channels R-HSA-1296071 9.467265e-01 0.024 0 0
ECM proteoglycans R-HSA-3000178 9.474684e-01 0.023 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.507353e-01 0.022 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.507692e-01 0.022 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.507991e-01 0.022 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.507991e-01 0.022 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.507991e-01 0.022 0 0
Fertilization R-HSA-1187000 9.507991e-01 0.022 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.541900e-01 0.020 0 0
Activation of GABAB receptors R-HSA-991365 9.545493e-01 0.020 0 0
GABA B receptor activation R-HSA-977444 9.545493e-01 0.020 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 9.553587e-01 0.020 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.553587e-01 0.020 0 0
TRP channels R-HSA-3295583 9.553587e-01 0.020 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 9.553587e-01 0.020 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.573623e-01 0.019 0 0
Synthesis of PE R-HSA-1483213 9.594960e-01 0.018 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.597655e-01 0.018 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.597655e-01 0.018 0 0
tRNA Aminoacylation R-HSA-379724 9.603277e-01 0.018 0 0
Metabolism of polyamines R-HSA-351202 9.603277e-01 0.018 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.613466e-01 0.017 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.630616e-01 0.016 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.630985e-01 0.016 0 0
Insulin receptor recycling R-HSA-77387 9.632501e-01 0.016 0 0
Telomere Extension By Telomerase R-HSA-171319 9.632501e-01 0.016 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.663561e-01 0.015 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 9.666564e-01 0.015 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.666564e-01 0.015 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.669441e-01 0.015 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.671620e-01 0.015 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.671620e-01 0.015 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.671620e-01 0.015 0 0
Neurotransmitter clearance R-HSA-112311 9.697472e-01 0.013 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.725517e-01 0.012 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.743338e-01 0.011 0 0
DAG1 glycosylations R-HSA-8931838 9.750963e-01 0.011 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.762495e-01 0.010 0 0
Kidney development R-HSA-9830369 9.762495e-01 0.010 0 0
G alpha (s) signalling events R-HSA-418555 9.762498e-01 0.010 0 0
Azathioprine ADME R-HSA-9748787 9.763687e-01 0.010 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.763959e-01 0.010 0 0
Cardiogenesis R-HSA-9733709 9.774052e-01 0.010 0 0
Recycling of bile acids and salts R-HSA-159418 9.774052e-01 0.010 0 0
The phototransduction cascade R-HSA-2514856 9.782470e-01 0.010 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.795001e-01 0.009 0 0
Heme degradation R-HSA-189483 9.795001e-01 0.009 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.814009e-01 0.008 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 9.814009e-01 0.008 0 0
Extracellular matrix organization R-HSA-1474244 9.823447e-01 0.008 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.831256e-01 0.007 0 0
Paracetamol ADME R-HSA-9753281 9.844139e-01 0.007 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.846904e-01 0.007 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.859682e-01 0.006 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.861102e-01 0.006 0 0
Collagen chain trimerization R-HSA-8948216 9.861102e-01 0.006 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.864668e-01 0.006 0 0
Dectin-2 family R-HSA-5621480 9.868223e-01 0.006 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 9.873984e-01 0.006 0 0
Purine salvage R-HSA-74217 9.873984e-01 0.006 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.885672e-01 0.005 0 0
Interleukin-2 family signaling R-HSA-451927 9.896277e-01 0.005 0 0
Tryptophan catabolism R-HSA-71240 9.896277e-01 0.005 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.896277e-01 0.005 0 0
GABA receptor activation R-HSA-977443 9.897695e-01 0.004 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.905898e-01 0.004 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.908588e-01 0.004 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.914628e-01 0.004 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.922548e-01 0.003 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.933930e-01 0.003 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.936253e-01 0.003 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.938612e-01 0.003 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.942168e-01 0.003 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.942168e-01 0.003 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.948606e-01 0.002 0 0
Synthesis of PC R-HSA-1483191 9.952404e-01 0.002 0 0
Peptide hormone metabolism R-HSA-2980736 9.955286e-01 0.002 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.956458e-01 0.002 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.956821e-01 0.002 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.960055e-01 0.002 0 0
Metabolism of cofactors R-HSA-8978934 9.960055e-01 0.002 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.960828e-01 0.002 0 0
Neurotransmitter release cycle R-HSA-112310 9.962619e-01 0.002 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.964464e-01 0.002 0 0
Keratinization R-HSA-6805567 9.964955e-01 0.002 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.967763e-01 0.001 0 0
Complex IV assembly R-HSA-9864848 9.967763e-01 0.001 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.967763e-01 0.001 0 0
G alpha (q) signalling events R-HSA-416476 9.967804e-01 0.001 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.971743e-01 0.001 0 0
Nucleotide biosynthesis R-HSA-8956320 9.973470e-01 0.001 0 0
Cholesterol biosynthesis R-HSA-191273 9.978232e-01 0.001 0 0
Synthesis of PA R-HSA-1483166 9.982034e-01 0.001 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.982716e-01 0.001 0 0
Sialic acid metabolism R-HSA-4085001 9.985216e-01 0.001 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.986589e-01 0.001 0 0
Phospholipid metabolism R-HSA-1483257 9.986791e-01 0.001 0 0
Nucleotide salvage R-HSA-8956321 9.987834e-01 0.001 0 0
Collagen degradation R-HSA-1442490 9.987834e-01 0.001 0 0
G alpha (i) signalling events R-HSA-418594 9.988873e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.989989e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.990919e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.992179e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.993149e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.993222e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.993852e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.994215e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.995124e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.995412e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.995838e-01 0.000 0 0
Aspirin ADME R-HSA-9749641 9.996225e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.996468e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.996584e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.997386e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.997654e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.997682e-01 0.000 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.997898e-01 0.000 0 0
PPARA activates gene expression R-HSA-1989781 9.997942e-01 0.000 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.998233e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.999037e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999117e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999164e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.999349e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999420e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999512e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999785e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999798e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999876e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999938e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999938e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999939e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999944e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999952e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.999982e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999982e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999984e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999987e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999992e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999992e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999994e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999994e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999995e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999995e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999996e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999998e-01 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways