PAK3
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| B2RPK0 | S15 | Sugiyama | HMGB1P1 HMG1L1 HMGB1L1 | ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHSDAS |
| O00231 | S298 | Sugiyama | PSMD11 | RYAGRQTEALKCVAQASKNRsLADFEKALTDYRAELRDDPI |
| O00273 | S37 | Sugiyama | DFFA DFF1 DFF45 H13 | TLKPCLLRRNysREQHGVAAsCLEDLRSKACDILAIDKSLT |
| O00429 | S44 | Sugiyama | DNM1L DLP1 DRP1 | QLPQIVVVGTQSSGKSsVLEsLVGRDLLPRGTGIVTRRPLI |
| O00571 | S594 | Sugiyama | DDX3X DBX DDX3 | MAyEHHyKGssRGRSKssRFsGGFGARDYRQssGAssssFs |
| O00571 | S82 | Sugiyama | DDX3X DBX DDX3 | ssKDKDAyssFGsRsDsRGKssFFsDRGsGsRGRFDDRGRs |
| O14974 | S692 | Sugiyama | PPP1R12A MBS MYPT1 | PVRDEEsEsQRKARSRQARQsRRstQGVtLtDLQEAEKtIG |
| O14974 | S903 | Sugiyama | PPP1R12A MBS MYPT1 | QtDsIsRyETssTsAGDRyDsLLGRsGsysYLEERKPYSSR |
| O14974 | S912 | Sugiyama | PPP1R12A MBS MYPT1 | TssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDSTDF |
| O14974 | T696 | Sugiyama | PPP1R12A MBS MYPT1 | EEsEsQRKARSRQARQsRRstQGVtLtDLQEAEKtIGRSRS |
| O14980 | S1055 | Sugiyama | XPO1 CRM1 | LEEREIALRQADEEKHKRQMsVPGIFNPHEIPEEMCD____ |
| O15013 | S1330 | Sugiyama | ARHGEF10 KIAA0294 | LKDPVSLRSKARRAKKAKASsALVVCGGQGHRRVHRKARQP |
| O15212 | S101 | Sugiyama | PFDN6 HKE2 PFD6 | DyItAEIKRYESQLRDLERQsEQQREtLAQLQQEFQRAQAA |
| O15234 | T13 | Sugiyama | CASC3 MLN51 | ________MADRRRQRAsQDtEDEESGASGsDsGGsPLRGG |
| O15372 | S290 | Sugiyama | EIF3H EIF3S3 | QQQQKHQYQQRRQQENMQRQsRGEPPLPEEDLsKLFKPPQP |
| O15523 | S592 | Sugiyama | DDX3Y DBY | MAyEHHyKGGSRGRSKSNRFsGGFGARDYRQSSGSSSSGFG |
| O43399 | S104 | Sugiyama | TPD52L2 | stLGELKQNLsRsWHDVQVssAyVKTSEKLGEWNEKVTQSD |
| O43423 | S100 | Sugiyama | ANP32CP PP32R1 | AEKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCE |
| O43488 | S40 | Sugiyama | AKR7A2 AFAR AFAR1 AKR7 | SPPPEARALAMSRPPPPRVAsVLGTMEMGRRMDAPAsAAAV |
| O43707 | S423 | Sugiyama | ACTN4 | NEIRRLERLDHLAEKFRQKAsIHEAWtDGKEAMLKHRDyEt |
| O43823 | S124 | Sugiyama | AKAP8 AKAP95 | SKEGGRGGsGGGGEGIQDREssFRFQPFESYDSRPCLPEHN |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60573 | S74 | Sugiyama | EIF4E2 EIF4EL3 | HPLQYNYTFWYSRRtPGRPtsSQSyEQNIKQIGTFASVEQF |
| O60664 | S175 | Sugiyama | PLIN3 M6PRBP1 TIP47 | RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK |
| O60739 | T45 | Sugiyama | EIF1B | AGTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKK |
| O60749 | S365 | Sugiyama | SNX2 TRG9 | AKSAAMLGNsEDHTALSRALsQLAEVEEKIDQLHQEQAFAD |
| O60763 | S851 | Sugiyama | USO1 VDP | VQGETETIIATKTTDVEGRLsALLQETKELKNEIKALSEER |
| O60814 | S39 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| O60841 | S182 | Sugiyama | EIF5B IF2 KIAA0741 | DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK |
| O60841 | S183 | Sugiyama | EIF5B IF2 KIAA0741 | GsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKN |
| O60841 | S186 | Sugiyama | EIF5B IF2 KIAA0741 | EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN |
| O60841 | T78 | Sugiyama | EIF5B IF2 KIAA0741 | ILKELEELsLEAQGIKADREtVAVKPTENNEEEFtsKDKKK |
| O75348 | S68 | Sugiyama | ATP6V1G1 ATP6G ATP6G1 ATP6J | RLQREKEFKAKEAAALGsRGsCstEVEKETQEKMTILQtyF |
| O75348 | T71 | Sugiyama | ATP6V1G1 ATP6G ATP6G1 ATP6J | REKEFKAKEAAALGsRGsCstEVEKETQEKMTILQtyFRQN |
| O75643 | S17 | Sugiyama | SNRNP200 ASCC3L1 BRR2 HELIC2 KIAA0788 | ____MADVTARsLQYEYKANsNLVLQADRsLIDRTRRDEPT |
| O75665 | S899 | Sugiyama | OFD1 CXorf5 | EEKIREQQVKERRQREERRQsNLQEVLERERRELEKLyQER |
| O75821 | S28 | Sugiyama | EIF3G EIF3S4 | sKPsWADQVEEEGEDDKCVtsELLKGIPLAtGDtsPEPELL |
| O75914 | S120 | Sugiyama | PAK3 OPHN3 | MCPGKLPEGIPEQWARLLQtsNItKLEQKKNPQAVLDVLKF |
| O75914 | S143 | Sugiyama | PAK3 OPHN3 | tKLEQKKNPQAVLDVLKFYDsKEtVNNQKYMsFTSGDKSAH |
| O75914 | S154 | SIGNOR|Sugiyama | PAK3 OPHN3 | VLDVLKFYDsKEtVNNQKYMsFTSGDKSAHGYIAAHPSSTK |
| O75914 | S239 | Sugiyama | PAK3 OPHN3 | RsVVESIASPAVPNKEVTPPsAENANSstLYRNtDRQRKKs |
| O75914 | S246 | Sugiyama | PAK3 OPHN3 | ASPAVPNKEVTPPsAENANSstLYRNtDRQRKKsKMTDEEI |
| O75914 | S50 | Sugiyama | PAK3 OPHN3 | HSSKPLPMAPEEKNKKARLRsIFPGGGDKtNKKKEKERPEI |
| O75914 | T119 | Sugiyama | PAK3 OPHN3 | QMCPGKLPEGIPEQWARLLQtsNItKLEQKKNPQAVLDVLK |
| O75914 | T123 | Sugiyama | PAK3 OPHN3 | GKLPEGIPEQWARLLQtsNItKLEQKKNPQAVLDVLKFYDs |
| O75914 | T146 | Sugiyama | PAK3 OPHN3 | EQKKNPQAVLDVLKFYDsKEtVNNQKYMsFTSGDKSAHGYI |
| O75914 | T247 | Sugiyama | PAK3 OPHN3 | SPAVPNKEVTPPsAENANSstLYRNtDRQRKKsKMTDEEIL |
| O75914 | T252 | Sugiyama | PAK3 OPHN3 | NKEVTPPsAENANSstLYRNtDRQRKKsKMTDEEILEKLRs |
| O75914 | T59 | Sugiyama | PAK3 OPHN3 | PEEKNKKARLRsIFPGGGDKtNKKKEKERPEISLPSDFEHT |
| O75937 | S81 | Sugiyama | DNAJC8 SPF31 HSPC315 HSPC331 | VLQIDPEVTDEEIKKRFRQLsILVHPDKNQDDADRAQKAFE |
| O76021 | S314 | Sugiyama | RSL1D1 CATX11 CSIG PBK1 L12 | RNFEKQKERKKKRQQARKtAsVLsKDDVAPEsGDtTVKKPE |
| O76021 | T312 | Sugiyama | RSL1D1 CATX11 CSIG PBK1 L12 | RERNFEKQKERKKKRQQARKtAsVLsKDDVAPEsGDtTVKK |
| O95218 | S143 | Sugiyama | ZRANB2 ZIS ZNF265 | EyDEFGRKKKKYRGKAVGPAsILKEVEDKEsEGEEEDEDED |
| O95292 | S158 | Sugiyama | VAPB UNQ484/PRO983 | NKIIstTAsKtEtPIVSKsLsssLDDtEVKKVMEECKRLQG |
| O95297 | S260 | Sugiyama | MPZL1 PZR UNQ849/PRO1787 | IyAQLDHsGGHHSDKINKSEsVVyADIRKN___________ |
| O95302 | S275 | Sugiyama | FKBP9 FKBP60 FKBP63 | NPKDSISIENKVVPENCERIsQsGDFLRYHYNGTLLDGTLF |
| O95456 | S284 | Sugiyama | PSMG1 C21LRP DSCR2 PAC1 | KNIPQSTEILKKLMTTNEIQsNIyt________________ |
| O95626 | S104 | Sugiyama | ANP32D PP32R2 | AEKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCE |
| O95678 | S162 | Sugiyama | KRT75 K6HF KB18 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| O95757 | Y600 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | IDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERNDA |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S237 | Sugiyama | LDHA PIG19 | DLGtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVA |
| P00491 | S176 | Sugiyama | PNP NP | GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA |
| P00558 | S115 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | FLKDCVGPEVEKACANPAAGsVILLENLRFHVEEEGKGKDA |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | T369 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV |
| P00558 | T378 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA |
| P02538 | S176 | Sugiyama | KRT6A K6A KRT6D | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT |
| P02545 | S282 | Sugiyama | LMNA LMN1 | ELEKTYSAKLDNARQsAERNsNLVGAAHEELQQsRIRIDsL |
| P02545 | T436 | Sugiyama | LMNA LMN1 | tKKRKLEstEsRssFsQHARtsGRVAVEEVDEEGKFVRLRN |
| P04040 | S515 | Sugiyama | CAT | ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________ |
| P04040 | T511 | Sugiyama | CAT | SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____ |
| P04049 | S338 | GPS6|SIGNOR|ELM|iPTMNet | RAF1 RAF | RAPVsGtQEKNKIRPRGQRDssyyWEIEASEVMLSTRIGsG |
| P04049 | S339 | GPS6 | RAF1 RAF | APVsGtQEKNKIRPRGQRDssyyWEIEASEVMLSTRIGsGs |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S354 | Sugiyama | ALDOA ALDA | ANsLACQGKytPsGQAGAAAsEsLFVsNHAy__________ |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04083 | S170 | Sugiyama | ANXA1 ANX1 LPC1 | RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE |
| P04083 | S182 | Sugiyama | ANXA1 ANX1 LPC1 | RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD |
| P04259 | S176 | Sugiyama | KRT6B K6B KRTL1 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04792 | S78 | Sugiyama | HSPB1 HSP27 HSP28 | LPPAAIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVs |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05023 | S519 | Sugiyama | ATP1A1 | sEPQHLLVMKGAPERILDRCssILLHGKEQPLDEELKDAFQ |
| P05362 | S43 | Sugiyama | ICAM1 | GPGNAQTSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETP |
| P05387 | S29 | Sugiyama | RPLP2 D11S2243E RPP2 | LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK |
| P05783 | S127 | Sugiyama | KRT18 CYK18 PIG46 | RLESKIREHLEKKGPQVRDWsHyFKIIEDLRAQIFANtVDN |
| P05783 | S305 | Sugiyama | KRT18 CYK18 PIG46 | QSAEVGAAETTLTELRRtVQsLEIDLDsMRNLKAsLENsLR |
| P05783 | S93 | Sugiyama | KRT18 CYK18 PIG46 | GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR |
| P05787 | S104 | Sugiyama | KRT8 CYK8 | IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS |
| P05787 | S280 | Sugiyama | KRT8 CYK8 | IAEVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDL |
| P05787 | S330 | Sugiyama | KRT8 CYK8 | MNRNISRLQAEIEGLKGQRAsLEAAIADAEQRGELAIKDAN |
| P06733 | S268 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S349 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV |
| P06733 | S353 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | Y44 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK |
| P06899 | S39 | Sugiyama | H2BC11 H2BFR HIST1H2BJ | VTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKA |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T302 | Sugiyama | LDHB | YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07602 | S29 | Sugiyama | PSAP GLBA SAP1 | SLLGAALAGPVLGLKECtRGsAVWCQNVKTASDCGAVKHCL |
| P07711 | S326 | Sugiyama | CTSL CTSL1 | WGMGGyVKMAKDRRNHCGIAsAAsyPtV_____________ |
| P07737 | S77 | Sugiyama | PFN1 | ssFyVNGLtLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAP |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07900 | S391 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P07900 | S468 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | GIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQ |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S623 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | tyGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsII |
| P07900 | S63 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN |
| P07900 | T317 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08195 | S403 | Sugiyama | SLC3A2 MDU1 | SDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYL |
| P08238 | S206 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEDQtEyLEERRVKEVVKKHsQFIGyPItLyLEKEREKEIs |
| P08238 | S383 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S482 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | S58 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| P08238 | T214 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EERRVKEVVKKHsQFIGyPItLyLEKEREKEIsDDEAEEEK |
| P08238 | T309 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08670 | S325 | Sugiyama | VIM | NNDALRQAKQESTEYRRQVQsLtCEVDALKGtNEsLERQMR |
| P08708 | S89 | Sugiyama | RPS17 RPS17L | ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL |
| P08729 | S104 | Sugiyama | KRT7 SCL | LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT |
| P08758 | T8 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | _____________MAQVLRGtVtDFPGFDERADAEtLRKAM |
| P09429 | S15 | Sugiyama | HMGB1 HMG1 | ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAs |
| P09496 | S236 | Sugiyama | CLTA | RLCDFNPKSSKQAKDVSRMRsVLIsLKQAPLVH________ |
| P09496 | S240 | Sugiyama | CLTA | FNPKSSKQAKDVSRMRsVLIsLKQAPLVH____________ |
| P09497 | S144 | Sugiyama | CLTB | tEQEWREKAKKDLEEWNQRQsEQVEKNKINNRIADKAFYQQ |
| P09972 | S45 | Sugiyama | ALDOC ALDC | APGKGILAADEsVGsMAKRLsQIGVENtEENRRLYRQVLFs |
| P0CG47 | S57 | Sugiyama | UBB | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P0CG48 | S57 | Sugiyama | UBC | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P10412 | S36 | Sugiyama | H1-4 H1F4 HIST1H1E | EKtPVKKKARKsAGAAKRKAsGPPVsELItKAVAASKERsG |
| P10412 | S41 | Sugiyama | H1-4 H1F4 HIST1H1E | KKKARKsAGAAKRKAsGPPVsELItKAVAASKERsGVsLAA |
| P10809 | S488 | Sugiyama | HSPD1 HSP60 | IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG |
| P11142 | S340 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | S432 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMTKD |
| P11142 | S544 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KYKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKIND |
| P11142 | S85 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV |
| P11142 | T38 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11413 | S106 | Sugiyama | G6PD | PFFKATPEEKLKLEDFFARNsyVAGQyDDAAsyQRLNsHMN |
| P11413 | Y107 | Sugiyama | G6PD | FFKATPEEKLKLEDFFARNsyVAGQyDDAAsyQRLNsHMNA |
| P11586 | S129 | Sugiyama | MTHFD1 MTHFC MTHFD | INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P12035 | S211 | Sugiyama | KRT3 | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN |
| P12270 | S135 | Sugiyama | TPR | RTKEELEAEKRDLIRTNERLsQELEyLTEDVKRLNEKLKES |
| P12277 | S129 | Sugiyama | CKB CKBB | DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG |
| P12814 | S404 | Sugiyama | ACTN1 | NEIRRLERLDHLAEKFRQKAsIHEAWtDGKEAMLRQKDyEt |
| P13489 | S290 | Sugiyama | RNH1 PRI RNH | AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S38 | Sugiyama | EEF2 EF2 | NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD |
| P13639 | S578 | Sugiyama | EEF2 EF2 | LKDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNK |
| P13639 | S732 | Sugiyama | EEF2 EF2 | DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP |
| P13639 | T582 | Sugiyama | EEF2 EF2 | EEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRL |
| P13639 | Y579 | Sugiyama | EEF2 EF2 | KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH |
| P13647 | S181 | Sugiyama | KRT5 | IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P13797 | S339 | Sugiyama | PLS3 | PRIDINMsGFNETDDLKRAEsMLQQADKLGCRQFVTPADVV |
| P13807 | S710 | Sugiyama | GYS1 GYS | APEWPRRAsCTsSTSGSKRNsVDtAtsssLstPsEPLsPts |
| P13861 | S58 | Sugiyama | PRKAR2A PKR2 PRKAR2 | TRLREARAPAsVLPAAtPRQsLGHPPPEPGPDRVADAKGDs |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14314 | S478 | Sugiyama | PRKCSH G19P1 | DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS |
| P14618 | T45 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI |
| P14618 | T50 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S514 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK |
| P14625 | S650 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | KIEKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtG |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14866 | S543 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | ELGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLN |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15311 | S536 | Sugiyama | EZR VIL2 | KRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNE |
| P15328 | S149 | Sugiyama | FOLR1 FOLR | VLNVPLCKEDCEQWWEDCRTsYTCKSNWHKGWNWTSGFNKC |
| P15880 | S249 | Sugiyama | RPS2 RPS4 | CtAtLGNFAKATFDAISKTysyLtPDLWKEtVFtKsPyQEF |
| P15880 | T232 | Sugiyama | RPS2 RPS4 | KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt |
| P16070 | S71 | Sugiyama | CD44 LHR MDU2 MDU3 MIC4 | DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI |
| P16402 | S37 | Sugiyama | H1-3 H1F3 HIST1H1D | KtPVKKKAKKAGATAGKRKAsGPPVsELItKAVAASKERsG |
| P16402 | S42 | Sugiyama | H1-3 H1F3 HIST1H1D | KKAKKAGATAGKRKAsGPPVsELItKAVAASKERsGVsLAA |
| P16403 | S36 | Sugiyama | H1-2 H1F2 HIST1H1C | EKAPVKKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsG |
| P16403 | S41 | Sugiyama | H1-2 H1F2 HIST1H1C | KKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsGVsLAA |
| P16949 | S16 | Sugiyama | STMN1 C1orf215 LAP18 OP18 | _____MAssDIQVKELEKRAsGQAFELILsPRsKEsVPEFP |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17544 | S44 | Sugiyama | ATF7 ATFA | LAVHKHKHEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEV |
| P17600 | S605 | SIGNOR|iPTMNet | SYN1 | QQRQGPPQKPPGPAGPTRQAsQAGPVPRTGPPTTQQPRPSG |
| P17987 | S374 | Sugiyama | TCP1 CCT1 CCTA | ERICDDELILIKNTKARTsAsIILRGANDFMCDEMERSLHD |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18621 | S5 | Sugiyama | RPL17 | ________________MVRysLDPENPtKsCKSRGSNLRVH |
| P18621 | T79 | Sugiyama | RPL17 | PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE |
| P18669 | S118 | Sugiyama | PGAM1 PGAMA CDABP0006 | LNKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsK |
| P19338 | S328 | Sugiyama | NCL | NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P19429 | S150 | GPS6|SIGNOR|ELM|iPTMNet | TNNI3 TNNC1 | QKIFDLRGKFKRPtLRRVRIsADAMMQALLGARAKEsLDLR |
| P20618 | S162 | Sugiyama | PSMB1 PSC5 | DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG |
| P20810 | S366 | Sugiyama | CAST | DKDGKPLLPEPEEKPKPRsEsELIDELsEDFDRsECKEKPS |
| P21333 | S1522 | Sugiyama | FLNA FLN FLN1 | NADGTQTVNyVPSREGPysIsVLyGDEEVPRsPFKVKVLPT |
| P21333 | S2152 | Sugiyama | FLNA FLN FLN1 | VKVTGEGRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQ |
| P21333 | S2158 | Sugiyama | FLNA FLN FLN1 | GRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQDMtAQV |
| P21980 | S225 | Sugiyama | TGM2 | KNAGRDCsRRssPVYVGRVVsGMVNCNDDQGVLLGRWDNNY |
| P22626 | S189 | Sugiyama | HNRNPA2B1 HNRPA2B1 | IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF |
| P23142 | S247 | Sugiyama | FBLN1 PP213 | CRLGESCINTVGSFRCQRDssCGtGYELTEDNSCKDIDECE |
| P23381 | S357 | Sugiyama | WARS1 IFI53 WARS WRS | STFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAF |
| P23381 | S358 | Sugiyama | WARS1 IFI53 WARS WRS | TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs |
| P23527 | S39 | Sugiyama | H2BC17 H2BFH H2BFN HIST1H2BO | VTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKA |
| P23528 | S156 | Sugiyama | CFL1 CFL | QANCyEEVKDRCTLAEKLGGsAVIsLEGKPL__________ |
| P23528 | S160 | Sugiyama | CFL1 CFL | yEEVKDRCTLAEKLGGsAVIsLEGKPL______________ |
| P23588 | S207 | Sugiyama | EIF4B | DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR |
| P23588 | T205 | Sugiyama | EIF4B | GRDRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYR |
| P23921 | S780 | Sugiyama | RRM1 RR1 | KEKVSKEEEEKERNtAAMVCsLENRDECLMCGS________ |
| P24534 | S141 | Sugiyama | EEF1B2 EEF1B EF1B | ERLAQYESKKAKKPALVAKssILLDVKPWDDEtDMAKLEEC |
| P25205 | S447 | Sugiyama | MCM3 | EQGRVTIAKAGIHARLNARCsVLAAANPVyGRyDQyKTPME |
| P25398 | S107 | Sugiyama | RPS12 | EWVGLCKIDREGKPRKVVGCsCVVVKDYGKESQAKDVIEEy |
| P25705 | S184 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | IGsKTRRRVGLKAPGIIPRIsVREPMQTGIKAVDsLVPIGR |
| P25705 | S76 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV |
| P25786 | S211 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | GLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDDDVsP |
| P25789 | S7 | Sugiyama | PSMA4 HC9 PSC9 | ______________MSRRyDsRttIFsPEGRLYQVEYAMEA |
| P25789 | T10 | Sugiyama | PSMA4 HC9 PSC9 | ___________MSRRyDsRttIFsPEGRLYQVEYAMEAIGH |
| P25789 | Y5 | Sugiyama | PSMA4 HC9 PSC9 | ________________MSRRyDsRttIFsPEGRLYQVEYAM |
| P26038 | S429 | Sugiyama | MSN | DQKKTQEQLALEMAELtARIsQLEMARQKKEsEAVEWQQKA |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | T24 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR |
| P26583 | S15 | Sugiyama | HMGB2 HMG2 | ______MGKGDPNKPRGKMssyAFFVQtCREEHKKKHPDss |
| P26639 | S282 | Sugiyama | TARS1 TARS | RGPHVRHTGKIKALKIHKNssTyWEGKADMETLQRIyGISF |
| P26639 | S702 | Sugiyama | TARS1 TARS | ISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEE |
| P26641 | T287 | Sugiyama | EEF1G EF1G PRO1608 | EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL |
| P27348 | S45 | Sugiyama | YWHAQ | CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI |
| P27348 | S63 | Sugiyama | YWHAQ | LLsVAyKNVVGGRRSAWRVIsSIEQKTDTSDKKLQLIKDYR |
| P27695 | S66 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | EDPPDQKtsPsGKPAtLKICsWNVDGLRAWIKKKGLDWVKE |
| P27708 | S1859 | Sugiyama | CAD | RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P27824 | S362 | Sugiyama | CANX | WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK |
| P29401 | S443 | Sugiyama | TKT | EDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAAN |
| P29401 | T444 | Sugiyama | TKT | DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S60 | Sugiyama | EEF1D EF1D | ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL |
| P30050 | S26 | Sugiyama | RPL12 | DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI |
| P30050 | T18 | Sugiyama | RPL12 | ___MPPKFDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLs |
| P30085 | S47 | Sugiyama | CMPK1 CMK CMPK UCK UMK UMPK | yGytHLSAGELLRDERKNPDsQyGELIEKYIKEGKIVPVEI |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | T167 | Sugiyama | PEBP1 PBP PEBP | GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK |
| P30086 | T65 | Sugiyama | PEBP1 PBP PEBP | QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH |
| P30086 | Y64 | Sugiyama | PEBP1 PBP PEBP | tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW |
| P30101 | S98 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | VPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGP |
| P30520 | S451 | Sugiyama | ADSS2 ADSS | FIEDELQIPVKWIGVGKsREsMIQLF_______________ |
| P30533 | S230 | Sugiyama | LRPAP1 A2MRAP | SDIKGSVLHSRHTELKEKLRsINQGLDRLRRVsHQGystEA |
| P30533 | S242 | Sugiyama | LRPAP1 A2MRAP | TELKEKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWD |
| P30533 | S350 | Sugiyama | LRPAP1 A2MRAP | RTKELGYTVKKHLQDLSGRIsRARHNEL_____________ |
| P31152 | S186 | GPS6 | MAPK4 ERK4 PRKM4 | IGDFGLARIVDQHYSHKGYLsEGLVTKWYRsPRLLLSPNNY |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P31939 | S554 | Sugiyama | ATIC PURH OK/SW-cl.86 | VSISSDAFFPFRDNVDRAKRsGVAyIAAPSGsAADKVVIEA |
| P31943 | S269 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH |
| P31946 | S47 | Sugiyama | YWHAB | AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P31946 | S65 | Sugiyama | YWHAB | LLsVAyKNVVGARRSsWRVIsSIEQKTERNEKKQQMGKEYR |
| P31947 | S45 | Sugiyama | SFN HME1 | FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI |
| P32119 | S112 | Sugiyama | PRDX2 NKEFB TDPX1 | KEGGLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFII |
| P32119 | T142 | Sugiyama | PRDX2 NKEFB TDPX1 | EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF |
| P33316 | S120 | Sugiyama | DUT | PsKRARPAEVGGMQLRFARLsEHAtAPTRGsARAAGYDLYS |
| P33778 | S39 | Sugiyama | H2BC3 H2BFF HIST1H2BB | ITKAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKA |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34931 | T40 | Sugiyama | HSPA1L | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P34932 | S76 | Sugiyama | HSPA4 APG2 HSPH2 | VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT |
| P35908 | S191 | Sugiyama | KRT2 KRT2A KRT2E | IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| P36578 | S55 | Sugiyama | RPL4 RPL1 | DIVNFVHTNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVAR |
| P36578 | S66 | Sugiyama | RPL4 RPL1 | KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P36578 | T62 | Sugiyama | RPL4 RPL1 | TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG |
| P36578 | Y52 | Sugiyama | RPL4 RPL1 | IRPDIVNFVHTNLRKNNRQPyAVsELAGHQtsAEsWGtGRA |
| P37108 | S25 | Sugiyama | SRP14 | EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt |
| P37802 | S145 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN |
| P37802 | S163 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37837 | S13 | Sugiyama | TALDO1 TAL TALDO TALDOR | ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA |
| P38606 | S384 | Sugiyama | ATP6V1A ATP6A1 ATP6V1A1 VPP2 | RLAEMPADSGYPAyLGARLAsFYERAGRVKCLGNPEREGSV |
| P38646 | S148 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | YDDPEVQKDIKNVPFKIVRAsNGDAWVEAHGKLYSPSQIGA |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P39023 | S13 | Sugiyama | RPL3 OK/SW-cl.32 | ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP |
| P39023 | S265 | Sugiyama | RPL3 OK/SW-cl.32 | HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY |
| P39687 | S104 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | AEKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCE |
| P39748 | S255 | Sugiyama | FEN1 RAD2 | CESIRGIGPKRAVDLIQKHKsIEEIVRRLDPNKYPVPENWL |
| P40222 | S65 | Sugiyama | TXLNA TXLN | GPGsSQAPRKPEGAQARTAQsGALRDVSEELSRQLEDILST |
| P40227 | S49 | Sugiyama | CCT6A CCT6 CCTZ | GLQDVLRTNLGPKGTMKMLVsGAGDIKLTKDGNVLLHEMQI |
| P40925 | S153 | Sugiyama | MDH1 MDHA | ANtNCLtAsKSAPSIPKENFsCLtRLDHNRAKAQIALKLGV |
| P41091 | S107 | Sugiyama | EIF2S3 EIF2G | KIYKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLV |
| P41567 | T45 | Sugiyama | EIF1 SUI1 | AGTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKK |
| P42166 | S159 | Sugiyama | TMPO LAP2 | RKLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsND |
| P42167 | S159 | Sugiyama | TMPO LAP2 | RKLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSND |
| P42677 | T74 | Sugiyama | RPS27 MPS1 | VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________ |
| P42773 | S154 | Sugiyama | CDKN2C CDKN6 | NHKGDTACDLARLYGRNEVVsLMQANGAGGATNLQ______ |
| P43034 | S152 | Sugiyama | PAFAH1B1 LIS1 MDCR MDS PAFAHA | IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM |
| P43243 | S807 | Sugiyama | MATR3 KIAA0723 | NVPVGIDYVIPKTGFYCKLCsLFYTNEEVAKNTHCSSLPHY |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P43490 | S35 | Sugiyama | NAMPT PBEF PBEF1 | TDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKYE |
| P46013 | S299 | Sugiyama | MKI67 | GLQGETQLLVSRKSRPKsGGsGHAVAEPAsPEQELDQNKGK |
| P46013 | S648 | Sugiyama | MKI67 | RVSISRsQHDILQMICSKRRsGAsEANLIVAKSWADVVKLG |
| P46060 | S454 | Sugiyama | RANGAP1 KIAA1835 SD | VstFLAFPsPEKLLRLGPKssVLIAQQTDTSDPEKVVSAFL |
| P46459 | S207 | Sugiyama | NSF | KAENSSLNLIGKAKTKENRQsIINPDWNFEKMGIGGLDKEF |
| P46776 | S106 | Sugiyama | RPL27A | tRVNAAKNKtGAAPIIDVVRsGyyKVLGKGKLPKQPVIVKA |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46776 | T72 | Sugiyama | RPL27A | yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK |
| P46776 | Y108 | Sugiyama | RPL27A | VNAAKNKtGAAPIIDVVRsGyyKVLGKGKLPKQPVIVKAKF |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46779 | S115 | Sugiyama | RPL28 | HMIRKNKYRPDLRMAAIRRAsAILRSQKPVMVKRKRTRPTK |
| P46779 | S76 | Sugiyama | RPL28 | DGKGVVVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHM |
| P46779 | T75 | Sugiyama | RPL28 | ADGKGVVVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRH |
| P46779 | T81 | Sugiyama | RPL28 | VVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKNK |
| P46782 | S75 | Sugiyama | RPS5 | RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH |
| P46940 | S727 | Sugiyama | IQGAP1 KIAA0051 | WDEPPNFVQNSMQLSREEIQsSIsGVTAAYNREQLWLANEG |
| P47712 | S727 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP |
| P47712 | T416 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | AFSILFNRVLGVSGSQsRGstMEEELENIttKHIVsNDssD |
| P48637 | S394 | Sugiyama | GSS | LyGEEMVQALKQLKDSEERAsyILMEKIEPEPFENCLLRPG |
| P48668 | S176 | Sugiyama | KRT6C KRT6E | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P49207 | Y32 | Sugiyama | RPL34 | sYNtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGR |
| P49419 | S84 | Sugiyama | ALDH7A1 ATQ1 | EVIttyCPANNEPIARVRQAsVADyEEtVKKAREAWKIWAD |
| P49588 | S775 | Sugiyama | AARS1 AARS | VTGAEAQKALRKAESLKKCLsVMEAKVKAQTAPNKDVQREI |
| P49736 | S229 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | sHGHNVFKERIsDMCKENREsLVVNyEDLAAREHVLAYFLP |
| P50395 | S396 | Sugiyama | GDI2 RABGDIB | IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD |
| P50395 | S427 | Sugiyama | GDI2 RABGDIB | ttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED__ |
| P50395 | T425 | Sugiyama | GDI2 RABGDIB | DAttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED |
| P50897 | T261 | Sugiyama | PPT1 CLN1 PPT | SEWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLV |
| P50990 | S23 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | LHVPKAPGFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTT |
| P50991 | S51 | Sugiyama | CCT4 CCTD SRB | AQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtIt |
| P51858 | T41 | Sugiyama | HDGF HMG1L2 | KGyPHWPARIDEMPEAAVKstANKYQVFFFGTHETAFLGPK |
| P52209 | S126 | Sugiyama | PGD PGDH | YRDTTRRCRDLKAKGILFVGsGVsGGEEGARyGPSLMPGGN |
| P52597 | S269 | Sugiyama | HNRNPF HNRPF | LSDGYGFTTDLFGRDLsyCLsGMyDHRYGDsEFtVQsTTGH |
| P52732 | S39 | Sugiyama | KIF11 EG5 KNSL1 TRIP5 | IQVVVRCRPFNLAERKAsAHsIVECDPVRKEVSVRTGGLAD |
| P52907 | S123 | Sugiyama | CAPZA1 | KEAsDPQPEEADGGLKsWREsCDsALRAYVKDHYSNGFCTV |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P53396 | S656 | Sugiyama | ACLY | IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR |
| P53999 | S56 | Sugiyama | SUB1 PC4 RPO2TC1 | PVKKQKTGETsRALsssKQssssRDDNMFQIGKMRYVSVRD |
| P54136 | T215 | Sugiyama | RARS1 RARS | IVDFssPNIAKEMHVGHLRStIIGESISRLFEFAGYDVLRL |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T39 | Sugiyama | HSPA2 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P54750 | S345 | Sugiyama | PDE1A | EMVLSTDMSGHFQQIKNIRNsLQQPEGIDRAKTMSLILHAA |
| P55036 | S266 | Sugiyama | PSMD4 MCB1 | AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ |
| P55060 | S342 | Sugiyama | CSE1L CAS XPO2 | ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF |
| P55795 | S269 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH |
| P55884 | S185 | Sugiyama | EIF3B EIF3S9 | EEELLGDVLKDRPQEADGIDsVIVVDNVPQVGPDRLEKLKN |
| P56937 | S337 | Sugiyama | HSD17B7 17HSD7 SDR37C1 UNQ2563/PRO6243 | LELEKHIRVTIQKTDNQARLsGsCL________________ |
| P56937 | S339 | Sugiyama | HSD17B7 17HSD7 SDR37C1 UNQ2563/PRO6243 | LEKHIRVTIQKTDNQARLsGsCL__________________ |
| P57053 | S39 | Sugiyama | H2BC12L H2BFS H2BS1 | VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P57721 | T159 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | sQCGsLIGKGGSKIKEIREstGAQVQVAGDMLPNstERAVT |
| P58876 | S39 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | T90 | Sugiyama | TPI1 TPI | VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P61081 | S175 | Sugiyama | UBE2M UBC12 | NNRRLFEQNVQRSMRGGyIGstyFERCLK____________ |
| P61254 | S31 | Sugiyama | RPL26 | RsKNRKRHFNAPsHIRRKIMssPLSKELRQKYNVRSMPIRK |
| P61313 | S100 | Sugiyama | RPL15 EC45 TCBAP0781 | tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW |
| P61353 | S39 | Sugiyama | RPL27 | SGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMGK |
| P61353 | S86 | Sugiyama | RPL27 | SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL |
| P61978 | S401 | Sugiyama | HNRNPK HNRPK | GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI |
| P61978 | S417 | Sugiyama | HNRNPK HNRPK | DLAGsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITI |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | S46 | Sugiyama | YWHAG | AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P61981 | S64 | Sugiyama | YWHAG | LLsVAyKNVVGARRSsWRVIsSIEQKtsADGNEKKIEMVRA |
| P62241 | S160 | Sugiyama | RPS8 OK/SW-cl.83 | KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S46 | Sugiyama | YWHAE | SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62269 | Y95 | Sugiyama | RPS18 D6S218E | RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK |
| P62273 | S9 | Sugiyama | RPS29 | ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG |
| P62277 | S21 | Sugiyama | RPS13 | MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVKEQIyKLA |
| P62277 | T24 | Sugiyama | RPS13 | MHAPGKGLsQsALPyRRsVPtWLKLTsDDVKEQIyKLAKKG |
| P62280 | T15 | Sugiyama | RPS11 | ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR |
| P62333 | S244 | Sugiyama | PSMC6 SUG2 | DHQPCIIFMDEIDAIGGRRFsEGTSADREIQRTLMELLNQM |
| P62424 | T84 | Sugiyama | RPL7A SURF-3 SURF3 | QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP |
| P62633 | S121 | Sugiyama | CNBP RNF163 ZNF9 | CGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRCG |
| P62633 | Y120 | Sugiyama | CNBP RNF163 ZNF9 | NCGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRC |
| P62701 | T247 | Sugiyama | RPS4X CCG2 RPS4 SCAR | VIGKGNKPWIsLPRGKGIRLtIAEERDKRLAAKQSSG____ |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62805 | S48 | Sugiyama | H4C1 H4/A H4FA HIST1H4A; H4C2 H4/I H4FI HIST1H4B; H4C3 H4/G H4FG HIST1H4C; H4C4 H4/B H4FB HIST1H4D; H4C5 H4/J H4FJ HIST1H4E; H4C6 H4/C H4FC HIST1H4F; H4C8 H4/H H4FH HIST1H4H; H4C9 H4/M H4FM HIST1H4I; H4C11 H4/E H4FE HIST1H4J; H4C12 H4/D H4FD HIST1H4K; H4C13 H4/K H4FK HIST1H4L; H4C14 H4/N H4F2 H4FN HIST2H4 HIST2H4A; H4C15 H4/O H4FO HIST2H4B; H4C16 H4-16 HIST4H4 | QGItKPAIRRLARRGGVKRIsGLIyEETRGVLKVFLENVIR |
| P62807 | S39 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA |
| P62826 | S135 | Sugiyama | RAN ARA24 OK/SW-cl.81 | IPIVLCGNKVDIKDRKVKAKsIVFHRKKNLQyyDIsAKSNy |
| P62857 | S39 | Sugiyama | RPS28 | GRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLL |
| P62857 | T57 | Sugiyama | RPS28 | DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________ |
| P62899 | S15 | Sugiyama | RPL31 | ______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG |
| P62899 | T119 | Sugiyama | RPL31 | PNKLytLVtyVPVttFKNLQtVNVDEN______________ |
| P62906 | S64 | Sugiyama | RPL10A NEDD6 | QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH |
| P62906 | T9 | Sugiyama | RPL10A NEDD6 | ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62942 | T22 | Sugiyama | FKBP1A FKBP1 FKBP12 | GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD |
| P62979 | S57 | Sugiyama | RPS27A UBA80 UBCEP1 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA |
| P62987 | S57 | Sugiyama | UBA52 UBCEP2 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | S45 | Sugiyama | YWHAZ | CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI |
| P63104 | S63 | Sugiyama | YWHAZ | LLsVAyKNVVGARRssWRVVssIEQKTEGAEKKQQMAREYR |
| P63146 | S142 | Sugiyama | UBE2B RAD6B UBCH1 | ANSQAAQLYQENKREYEKRVsAIVEQsWNDS__________ |
| P63220 | S31 | Sugiyama | RPS21 | LYVPRKCSASNRIIGAKDHAsIQMNVAEVDKVTGRFNGQFK |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P67809 | S102 | Sugiyama | YBX1 NSEP1 YB1 | EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA |
| P67809 | S136 | Sugiyama | YBX1 NSEP1 YB1 | GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR |
| P67809 | S209 | Sugiyama | YBX1 NSEP1 YB1 | RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ |
| P67809 | T108 | Sugiyama | YBX1 NSEP1 YB1 | QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP |
| P67809 | Y99 | Sugiyama | YBX1 NSEP1 YB1 | DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68104 | T432 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P78345 | S253 | Sugiyama | RPP38 | DtsFEDLsKPKRKLADGRQAsVtLQPLKIKKLIPNPNKIRK |
| P78371 | S60 | Sugiyama | CCT2 99D8.1 CCTB | KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA |
| P78527 | S2955 | Sugiyama | PRKDC HYRC HYRC1 | EYDVLRGIFTSEIGTKQITQsALLAEARSDYSEAAKQYDEA |
| P83731 | S38 | Sugiyama | RPL24 | GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK |
| P83731 | S86 | Sugiyama | RPL24 | EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE |
| P83731 | T83 | Sugiyama | RPL24 | QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA |
| P84098 | S12 | Sugiyama | RPL19 | _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI |
| P84098 | S122 | Sugiyama | RPL19 | LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI |
| Q00587 | S350 | Sugiyama | CDC42EP1 BORG5 CEP1 MSE55 | HyPEMDARQERVEVLPQARAsWEsLDEEWRAPQAGsRtPVP |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01105 | S166 | Sugiyama | SET | yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q01546 | S196 | Sugiyama | KRT76 KRT2B KRT2P | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE |
| Q01970 | S1041 | Sugiyama | PLCB3 | TKEGEDEAKRYQEFQNRQVQsLLELREAQVDAEAQRRLEHL |
| Q02543 | S123 | Sugiyama | RPL18A | AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK |
| Q02790 | T278 | Sugiyama | FKBP4 FKBP52 | sWEMNsEEKLEQSTIVKERGtVYFKEGKYKQALLQYKKIVS |
| Q02818 | S369 | Sugiyama | NUCB1 NUC | RFEEELAAREAELNAKAQRLsQETEALGRsQGRLEAQKREL |
| Q02878 | S255 | Sugiyama | RPL6 TXREB1 | tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF |
| Q04695 | S28 | Sugiyama | KRT17 | FTSSSsIKGSSGLGGGsSRTsCRLsGGLGAGsCRLGSAGGL |
| Q04695 | S32 | Sugiyama | KRT17 | SsIKGSSGLGGGsSRTsCRLsGGLGAGsCRLGSAGGLGSTL |
| Q04917 | S145 | Sugiyama | YWHAH YWHA1 | KMKGDYYRYLAEVASGEKKNsVVEAsEAAyKEAFEISKEQM |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q04917 | S64 | Sugiyama | YWHAH YWHA1 | LLsVAyKNVVGARRSsWRVIsSIEQKTMADGNEKKLEKVKA |
| Q05639 | T432 | Sugiyama | EEF1A2 EEF1AL STN | VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT |
| Q05682 | S714 | SIGNOR | CALD1 CAD CDM | PTKPAASDLPVPAEGVRNIKsMWEKGNVFssPtAAGtPNKE |
| Q05682 | S744 | SIGNOR | CALD1 CAD CDM | sPtAAGtPNKEtAGLKVGVSsRINEWLTKtPDGNKsPAPKP |
| Q06210 | S261 | Sugiyama | GFPT1 GFAT GFPT | GsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDA |
| Q06830 | T143 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF |
| Q07020 | S140 | Sugiyama | RPL18 | ILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAPGtPH |
| Q07020 | T136 | Sugiyama | RPL18 | AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP |
| Q07021 | S210 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS |
| Q07866 | S389 | Sugiyama | KLC1 KLC KNS2 | YQTKLGPDDPNVAKTKNNLAsCyLKQGKFKQAETLYKEILT |
| Q07866 | Y391 | Sugiyama | KLC1 KLC KNS2 | TKLGPDDPNVAKTKNNLAsCyLKQGKFKQAETLYKEILTRA |
| Q09028 | S147 | Sugiyama | RBBP4 RBAP48 | VNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGEC |
| Q12789 | S844 | Sugiyama | GTF3C1 | SFISERRTIKQESGRAGVRPsssGsAWEACSEAPSKGSQDG |
| Q12906 | S20 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | _MRPMRIFVNDDRHVMAKHssVyPTQEELEAVQNMVsHtER |
| Q12906 | S46 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | EELEAVQNMVsHtERALKAVsDWIDEQEKGssEQAEsDNMD |
| Q13011 | S139 | Sugiyama | ECH1 | DLMDMASDILQPKGDDVARIsWYLRDIITRYQETFNVIERC |
| Q13136 | S239 | Sugiyama | PPFIA1 LIP1 | GVLDINHEQENtPstsGKRssDGsLsHEEDLAKVIELQEII |
| Q13136 | S666 | Sugiyama | PPFIA1 LIP1 | IQEEKENTEQRAEEIESRVGsGsLDNLGRFRSMssIPPYPA |
| Q13136 | T572 | Sugiyama | PPFIA1 LIP1 | LRRPQKGRLAALRDEPSKVQtLNEQDWERAQQASVLANVAQ |
| Q13153 | S110 | Sugiyama | PAK1 | DAVTGEFTGMPEQWARLLQtsNITKsEQKKNPQAVLDVLEF |
| Q13177 | S109 | Sugiyama | PAK2 | DAVTGEFTGMPEQWARLLQtsNItKLEQKKNPQAVLDVLKF |
| Q13177 | T108 | Sugiyama | PAK2 | FDAVTGEFTGMPEQWARLLQtsNItKLEQKKNPQAVLDVLK |
| Q13177 | T112 | Sugiyama | PAK2 | TGEFTGMPEQWARLLQtsNItKLEQKKNPQAVLDVLKFyDs |
| Q13263 | S784 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK |
| Q13283 | S67 | Sugiyama | G3BP1 G3BP | sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN |
| Q13428 | S85 | Sugiyama | TCOF1 | AEEDAALQAKKTRVsDPIstsEssEEEEEAEAETAKAtPRL |
| Q13428 | S996 | Sugiyama | TCOF1 | AQAQAAstPRKARASESTARssssEsEDEDVIPAtQCLtPG |
| Q13442 | S19 | Sugiyama | PDAP1 HASPP28 | __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE |
| Q13561 | S83 | Sugiyama | DCTN2 DCTN50 | GTKGLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKY |
| Q13596 | S368 | Sugiyama | SNX1 | AKSLAMLGSSEDNTALSRALsQLAEVEEKIEQLHQEQANND |
| Q14152 | S1028 | Sugiyama | EIF3A EIF3S10 KIAA0139 | NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP |
| Q14152 | S1188 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PWRPLVKPGGWREKEKAREEsWGPPRESRPsEEREWDREKE |
| Q14152 | S492 | Sugiyama | EIF3A EIF3S10 KIAA0139 | VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14157 | S356 | Sugiyama | UBAP2L KIAA0144 NICE4 | HsMVsMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLA |
| Q14157 | S360 | Sugiyama | UBAP2L KIAA0144 NICE4 | sMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLAAQHS |
| Q14157 | Y1082 | Sugiyama | UBAP2L KIAA0144 NICE4 | RSQTSSIPQKPQTNKSAYNSySWGAN_______________ |
| Q14160 | S493 | Sugiyama | SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL | RAtPHPSELKVMKRSIEGRRsEACPCQPDsGsPLPAEEEKR |
| Q14192 | S121 | Sugiyama | FHL2 DRAL SLIM3 | CQECKKTIMPGTRKMEYKGSsWHETCFICHRCQQPIGTKSF |
| Q14204 | S3257 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | NDKLKKMVKDQQEAEKKKVMsQEIQEQLHKQQEVIADKQMS |
| Q14498 | S336 | Sugiyama | RBM39 HCC1 RNPC2 | LAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGR |
| Q14566 | S271 | Sugiyama | MCM6 | VPDVSKLSTPGARAEtNsRVsGVDGyEtEGIRGLRALGVRD |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14697 | S916 | Sugiyama | GANAB G2AN KIAA0088 | GAGKPAAVVLQTKGSPEsRLsFQHDPEtsVLVLRKPGINVA |
| Q14847 | S99 | Sugiyama | LASP1 MLN50 | ELQsQVRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsN |
| Q14980 | S1991 | Sugiyama | NUMA1 NMP22 NUMA | QPIQIAEGTGITTRQQRKRVsLEPHQGPGtPEsKKATSCFP |
| Q14CN4 | S138 | Sugiyama | KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 | IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN |
| Q15021 | S1231 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | CQRFRTSRTERQQRDLAYCVsQLPLTERGLRKMLDNFDCFG |
| Q15021 | S585 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | ILGLIFKGPAASTQEKNPREstGNMVTGQTVCKNKPNMsDP |
| Q15021 | T586 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | LGLIFKGPAASTQEKNPREstGNMVTGQTVCKNKPNMsDPE |
| Q15029 | S944 | Sugiyama | EFTUD2 KIAA0031 SNRP116 | QPAPHLAREFMIKTRRRKGLsEDVsIsKFFDDPMLLELAKQ |
| Q15029 | S950 | Sugiyama | EFTUD2 KIAA0031 SNRP116 | AREFMIKTRRRKGLsEDVsIsKFFDDPMLLELAKQDVVLNY |
| Q15185 | S72 | Sugiyama | PTGES3 P23 TEBP | EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE |
| Q15365 | T127 | Sugiyama | PCBP1 | TQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT |
| Q15366 | T127 | Sugiyama | PCBP2 | sQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT |
| Q15417 | S259 | Sugiyama | CNN3 | DNSTISLQMGTNKVAsQKGMsVyGLGRQVYDPKYCAAPTEP |
| Q15427 | T14 | Sugiyama | SF3B4 SAP49 | _______MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFL |
| Q15428 | S153 | Sugiyama | SF3A2 SAP62 | LFQIDYPEIAEGIMPRHRFMsAyEQRIEPPDRRWQYLLMAA |
| Q15785 | S93 | Sugiyama | TOMM34 URCC3 | DCTSALALVPFSIKPLLRRAsAyEALEKYPMAYVDYKTVLQ |
| Q16543 | S339 | Sugiyama | CDC37 CDC37A | DAISKMDPTDAKYHMQRCIDsGLWVPNSKASEAKEGEEAGP |
| Q16576 | S146 | Sugiyama | RBBP7 RBAP46 | VNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGEC |
| Q16659 | S189 | GPS6 | MAPK6 ERK3 PRKM6 | IGDFGLARIMDPHYSHKGHLsEGLVTKWYRSPRLLLSPNNY |
| Q16778 | S39 | Sugiyama | H2BC21 H2BFQ HIST2H2BE | VTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKA |
| Q3SY84 | S143 | Sugiyama | KRT71 K6IRS1 KB34 KRT6IRS1 | IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q58FF6 | S34 | Sugiyama | HSP90AB4P | IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN |
| Q58FF7 | S185 | Sugiyama | HSP90AB3P HSP90BC | KEDQtEyLEERRVKEVVKKHsQFIGyPItLyLEKEQDKEIs |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | S58 | Sugiyama | HSP90AB3P HSP90BC | IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q58FF7 | T193 | Sugiyama | HSP90AB3P HSP90BC | EERRVKEVVKKHsQFIGyPItLyLEKEQDKEIsDDEAEEEK |
| Q58FF8 | S58 | Sugiyama | HSP90AB2P HSP90BB | IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN |
| Q5BKZ1 | Y93 | Sugiyama | ZNF326 ZIRD | PYESyDsRsSLGGRDLYRsGyGFNEPEQSRFGGSYGGRFES |
| Q5JTD0 | S361 | Sugiyama | TJAP1 PILT TJP4 | IPRNsPLPNCtyAtRQAISLsLVEEGSERARPSPVPSTPAS |
| Q5QNW6 | S39 | Sugiyama | H2BC18 HIST2H2BF | VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q5T0N5 | S488 | Sugiyama | FNBP1L C1orf39 TOCA1 | NEAWLSEVEGKTGGRGDRRHssDINHLVtQGREsPEGsytD |
| Q5T1M5 | S1162 | Sugiyama | FKBP15 KIAA0674 | EAGstVAGAALRPsHHsQRssLsGDEEDELFKGATLKALRP |
| Q5T5C0 | S692 | Sugiyama | STXBP5 LLGL3 | YGSNDPYRREPRSPRKsRQPsGAGLCDIsEGtVVPEDRCKS |
| Q5TBB1 | S191 | Sugiyama | RNASEH2B DLEU8 | VNQTVAALKTNNVNVSSRVQsTAFFSGDQASTDKEEDYIRY |
| Q5VT52 | S1068 | Sugiyama | RPRD2 KIAA0460 HSPC099 | SLTATDQQQQEEHYRIETRVsssCLDLPDSTEEKGAPIETL |
| Q5VT52 | S1069 | Sugiyama | RPRD2 KIAA0460 HSPC099 | LTATDQQQQEEHYRIETRVsssCLDLPDSTEEKGAPIETLG |
| Q5VTE0 | T432 | Sugiyama | EEF1A1P5 EEF1AL3 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| Q5XKE5 | S155 | Sugiyama | KRT79 K6L KB38 KRT6L | IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| Q6DN03 | S39 | Sugiyama | H2BC20P HIST2H2BC | VTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKA |
| Q6DRA6 | S39 | Sugiyama | H2BC19P HIST2H2BD | VTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKA |
| Q6GYQ0 | S797 | Sugiyama | RALGAPA1 GARNL1 KIAA0884 TULIP1 | EtGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDM |
| Q6IBS0 | S140 | Sugiyama | TWF2 PTK9L MSTP011 | ELFGTVKDDLSFAGyQKHLssCAAPAPLtsAERELQQIRIN |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6UVK1 | S1857 | Sugiyama | CSPG4 MCSP | ASVPLRLTRGSRAPISRAQLsVVDPDSAPGEIEyEVQRAPH |
| Q6UVK1 | S321 | Sugiyama | CSPG4 MCSP | DQYPTHTSNRGVLSYLEPRGsLLLGGLDAEASRHLQEHRLG |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q71UM5 | T74 | Sugiyama | RPS27L | VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________ |
| Q7KZF4 | S150 | Sugiyama | SND1 TDRD11 | EGLAtRREGMRANNPEQNRLsECEEQAKAAKKGMWSEGNGS |
| Q7RTS7 | S153 | Sugiyama | KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 | IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q7Z417 | T685 | Sugiyama | NUFIP2 KIAA1321 PIG1 | HTKEMEsIWNLQKQDPKRIItyNEAMDsPDQ__________ |
| Q7Z4V5 | S300 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | AEKPLPKPRGRKPKPERPPSssSSDSDSDEVDRISEWKRRD |
| Q7Z4V5 | S395 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | REDDEPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKK |
| Q7Z4V5 | S396 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | EDDEPVKKRGRKGRGRGPPsssDsEPEAELEREAKKSAKKP |
| Q7Z5L9 | S15 | Sugiyama | IRF2BP2 | ______MAAAVAVAAASRRQsCyLCDLPRMPWAMIWDFTEP |
| Q7Z5L9 | S457 | Sugiyama | IRF2BP2 | GSHASKDANQVHSTTRRNsNsPPsPssMNQRRLGPREVGGQ |
| Q7Z794 | S177 | Sugiyama | KRT77 KRT1B | IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| Q86SQ0 | S719 | Sugiyama | PHLDB2 LL5B | SMREQLQQQLKRDADLLDVEsKHFEDLEFQQLEHESRLDEE |
| Q86TB9 | S564 | Sugiyama | PATL1 OK/KNS-cl.5 | LLSLEEERPALMDDRKHKICsMYDNLRGKLPGQERPSDDHF |
| Q86UE4 | S494 | Sugiyama | MTDH AEG1 LYRIC | PVNtsKTRPKQEKAFSLKtIstsDPAEVLVKNSQPIKTLPP |
| Q86UY5 | S331 | Sugiyama | FAM83A TSGP | GAAPANGRLSSSSGSASDRTsSNPFSGRSAGSHPGTRsVsA |
| Q86V48 | S957 | Sugiyama | LUZP1 | PTRIGKNVESTNSNAytQRsstDFsELEQPRSCLFEQGTRR |
| Q86VQ1 | S223 | Sugiyama | GLCCI1 | QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR |
| Q86Y46 | S145 | Sugiyama | KRT73 K6IRS3 KB36 KRT6IRS3 | IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q8IXH6 | S208 | Sugiyama | TP53INP2 C20orf110 DOR PINH | AVQRQNRARESRPRRSKNQSsFIyQPCQRQFNY________ |
| Q8IZ21 | S117 | Sugiyama | PHACTR4 PRO2963 | KPSDAMLKNGHTTPIGNARsssPVQVEEEPVRLAsLRKAIP |
| Q8N0Y7 | S118 | Sugiyama | PGAM4 PGAM3 | LNKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsK |
| Q8N142 | S452 | Sugiyama | ADSS1 ADSSL1 | FVENHVGVAVKWVGVGKsREsMIQLF_______________ |
| Q8N257 | S39 | Sugiyama | H2BC26 H2BU1 HIST3H2BB | VTKAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKA |
| Q8N684 | S166 | Sugiyama | CPSF7 | PGKVLNGEKVDVRPAtRQNLsQFEAQARKRECVRVPRGGIP |
| Q8N6T3 | T291 | Sugiyama | ARFGAP1 ARF1GAP | GVsQLAsKVQGVGSKGWRDVttFFsGKAEGPLDsPSEGHSy |
| Q8N6T3 | T292 | Sugiyama | ARFGAP1 ARF1GAP | VsQLAsKVQGVGSKGWRDVttFFsGKAEGPLDsPSEGHSyQ |
| Q8NBJ7 | S256 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG |
| Q8NBS9 | S426 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | KKVSEHSGGRDLDSLHRFVLsQAKDEL______________ |
| Q8NFD5 | S1744 | Sugiyama | ARID1B BAF250B DAN15 KIAA1235 OSA2 | ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI |
| Q8TCS8 | S767 | Sugiyama | PNPT1 PNPASE | LSRKVLQsPAtTVVRTLNDRssIVMGEPIsQSSSNsQ____ |
| Q8TD47 | T247 | Sugiyama | RPS4Y2 RPS4Y2P | VIGNGNKPWISLPRGKGIRLtIAEERDKRLAAKQSSG____ |
| Q92734 | S183 | Sugiyama | TFG | AsMsAFDPLKNQDEINKNVMsAFGLtDDQVsGPPsAPAEDR |
| Q93079 | S39 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q969S3 | S38 | Sugiyama | ZNF622 ZPR9 | MQRAHYKTDWHRYNLRRKVAsMAPVTAEGFQERVRAQRAVA |
| Q96CT7 | S122 | Sugiyama | CCDC124 | DtLRRDHQLREAPDTAEKAKsHLEVPLEENVNRRVLEEGsV |
| Q96D15 | S117 | Sugiyama | RCN3 UNQ239/PRO272 | VsLAELRAWIAHTQQRHIRDsVsAAWDtyDtDRDGRVGWEE |
| Q96JP5 | S177 | Sugiyama | ZFP91 ZNF757 FKSG11 | TSVSRHRDTENTRSSRSKTGsLQLICKSEPNTDQLDYDVGE |
| Q96RS6 | S373 | Sugiyama | NUDCD1 CML66 | EGLTWPELVIGDKQGELIRDsAQCAAIAERLMHLtsEELNP |
| Q96ST2 | S561 | Sugiyama | IWS1 IWS1L | GKRRRNRDGGtFIsDADDVVsAMIVKMNEAAEEDRQLNNQK |
| Q96ST2 | T551 | Sugiyama | IWS1 IWS1L | MMLQRKKSMSGKRRRNRDGGtFIsDADDVVsAMIVKMNEAA |
| Q99523 | S793 | SIGNOR | SORT1 | AGVLIVKKYVCGGRFLVHRysVLQQHAEANGVDGVDALDtA |
| Q99584 | S34 | Sugiyama | S100A13 | ETVVTTFFTFARQEGRKDsLsVNEFKELVTQQLPHLLKDVG |
| Q99613 | S154 | Sugiyama | EIF3C EIF3S8 | NAKALSTLRQKIRKyNRDFEsHItSyKQNPEQsADEDAEKN |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q99700 | S505 | Sugiyama | ATXN2 ATX2 SCA2 TNRC13 | SINTRENKYIPPGQRNREVIsWGsGRQNsPRMGQPGsGSMP |
| Q99798 | S388 | Sugiyama | ACO2 | AEKEGWPLDIRVGLIGSCTNssyEDMGRSAAVAKQALAHGL |
| Q99832 | S59 | Sugiyama | CCT7 CCTH NIP7-1 | TLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTL |
| Q99832 | T371 | Sugiyama | CCT7 CCTH NIP7-1 | tQIGGERyNFFtGCPKAKTCtFILRGGAEQFMEEtERSLHD |
| Q99877 | S39 | Sugiyama | H2BC15 H2BFD HIST1H2BN | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99879 | S39 | Sugiyama | H2BC14 H2BFE HIST1H2BM | INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99880 | S39 | Sugiyama | H2BC13 H2BFC HIST1H2BL | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q9BRS2 | S130 | Sugiyama | RIOK1 RIO1 | DKVLRKFENKINLDKLNVtDsVINKVTEKSRQKEADMYRIK |
| Q9BWG6 | S199 | Sugiyama | SCNM1 | PAPMsPtRRRALDHyLTLRSsGWIPDGRGRWVKDENVEFDs |
| Q9BX68 | T54 | Sugiyama | HINT2 | VTDGNEVAKAQQAtPGGAAPtIFsRILDKsLPADILyEDQQ |
| Q9BXP5 | S422 | Sugiyama | SRRT ARS2 ASR2 | EKPKDAAGLECKPRPLHKTCsLFMRNIAPNISRAEIIsLCK |
| Q9BY44 | S526 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | sPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKLKA |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9C0C2 | S983 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | sGGsSRtLDAQDRsFGtRPLssGFsPEEAQQQDEEFEKKIP |
| Q9GZT3 | S15 | Sugiyama | SLIRP C14orf156 DC23 DC50 PD04872 | ______MAASAARGAAALRRsINQPVAFVRRIPWTAASSQL |
| Q9H0B6 | S374 | Sugiyama | KLC2 | YATRLGPDDPNVAKTKNNLAsCyLKQGKYQDAETLYKEILT |
| Q9H0B6 | S428 | Sugiyama | KLC2 | NKPIWMHAEEREESKDKRRDsAPyGEyGsWYKACKVDsPtV |
| Q9H0B6 | S436 | Sugiyama | KLC2 | EEREESKDKRRDsAPyGEyGsWYKACKVDsPtVNTTLRSLG |
| Q9H0B6 | Y376 | Sugiyama | KLC2 | TRLGPDDPNVAKTKNNLAsCyLKQGKYQDAETLYKEILTRA |
| Q9H4I2 | S658 | Sugiyama | ZHX3 KIAA0395 TIX1 | LDEELDRLRSEtKMTRREIDsWFSERRKKVNAEETKKAEEN |
| Q9H788 | Y131 | Sugiyama | SH2D4A PPP1R38 SH2A | EEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKDIWKKVAE |
| Q9H7D7 | S121 | Sugiyama | WDR26 CDW2 MIP2 PRO0852 | ASSSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLN |
| Q9NPD3 | S240 | Sugiyama | EXOSC4 RRP41 SKI6 | AARDVHTLLDRVVRQHVREAsILLGD_______________ |
| Q9NQY0 | S248 | Sugiyama | BIN3 | HSDEQRERENEAKLSELRALsIVADD_______________ |
| Q9NRY5 | S209 | Sugiyama | FAM114A2 C5orf3 | AEGDPGFKRTKGLMNRNATLsQVLREAKEKEEIRTSNEVTV |
| Q9NSB2 | S178 | Sugiyama | KRT84 KRTHB4 | AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS |
| Q9NSK0 | S387 | Sugiyama | KLC4 KNSL8 | YEGQLGPDNPNVARTKNNLAsCyLKQGKYAEAETLYKEILT |
| Q9NSK0 | Y389 | Sugiyama | KLC4 KNSL8 | GQLGPDNPNVARTKNNLAsCyLKQGKYAEAETLYKEILTRA |
| Q9NX58 | S32 | Sugiyama | LYAR PNAS-5 | sVKKIQVEKHVSVCRNCECLsCIDCGKDFWGDDYKNHVKCI |
| Q9NYF8 | S319 | Sugiyama | BCLAF1 BTF KIAA0164 | RsPAKtIAPQNAPRDEsRGRssFyPDGGDQETAKtGKFLKR |
| Q9NYF8 | S320 | Sugiyama | BCLAF1 BTF KIAA0164 | sPAKtIAPQNAPRDEsRGRssFyPDGGDQETAKtGKFLKRF |
| Q9NYU2 | T724 | Sugiyama | UGGT1 GT UGCGL1 UGGT UGT1 UGTR | RDYLDLTASNNFFVDDYARFtILDSQGKTAAVANSMNYLTK |
| Q9NZB2 | S990 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | FPLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKN |
| Q9P287 | S12 | Sugiyama | BCCIP TOK1 | _________MASRSKRRAVEsGVPQPPDPPVQRDEEEEKEV |
| Q9P2E9 | S655 | Sugiyama | RRBP1 KIAA1398 | GEPGPPDADGPLyLPYKTLVstVGsMVFNEGEAQRLIEILS |
| Q9P2E9 | S659 | Sugiyama | RRBP1 KIAA1398 | PPDADGPLyLPYKTLVstVGsMVFNEGEAQRLIEILSEKAG |
| Q9UGV2 | T332 | Sugiyama | NDRG3 | GMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQs |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UII2 | S63 | Sugiyama | ATP5IF1 ATPI ATPIF1 | AGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEIVHHKK |
| Q9ULD2 | S1259 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | LCsPKRsPtssAIPLQsPRNsGsFPsPsIsPR_________ |
| Q9ULX3 | S390 | Sugiyama | NOB1 ART4 NOB1P PSMD8BP1 MSTP158 | VsPFVENDISSRSATLQVRDsTLGAGRRRLNPNASRKKFVK |
| Q9ULX6 | T267 | Sugiyama | AKAP8L NAKAP NAKAP95 HRIHFB2018 | RFGFGFGNGMKQMRRTWKTWtTADFRTKKKKRKQGGsPDEP |
| Q9UM54 | T405 | SIGNOR|iPTMNet | MYO6 KIAA0389 | DLRVSLTTRVMLTTAGGTKGtVIKVPLKVEQANNARDALAK |
| Q9UNF1 | S264 | Sugiyama | MAGED2 BCG1 | sLRsPKARRGKARRRAAKLQssQEPEAPPPRDVALLQGRAN |
| Q9UNN5 | S518 | Sugiyama | FAF1 UBXD12 UBXN3A CGI-03 | EDEREARENVKREQDEAyRLsLEADRAKREAHEREMAEQFR |
| Q9UNX3 | S31 | Sugiyama | RPL26L1 RPL26P1 | RsKNRKRHFNAPSHVRRKIMssPLSKELRQKYNVRSMPIRK |
| Q9UNZ2 | S176 | Sugiyama | NSFL1C UBXN2C | RLGAAPEEEsAyVAGEKRQHssQDVHVVLKLWKsGFsLDNG |
| Q9UPQ0 | S377 | Sugiyama | LIMCH1 KIAA1102 | LREEDDKWQDDLARWKSRRRsVsQDLIKKEEERKKMEKLLA |
| Q9UPY8 | S176 | Sugiyama | MAPRE3 | AVPQRtsPtGPKNMQTSGRLsNVAPPCILRKNPPSARNGGH |
| Q9UQ80 | S267 | Sugiyama | PA2G4 EBP1 | YKRDPSKQYGLKMKtSRAFFsEVERRFDAMPFtLRAFEDEK |
| Q9UQ80 | S335 | Sugiyama | PA2G4 EBP1 | FVAQFKFTVLLMPNGPMRITsGPFEPDLyKsEMEVQDAELK |
| Q9Y230 | S431 | Sugiyama | RUVBL2 INO80J TIP48 TIP49B CGI-46 | LVCRKRKGtEVQVDDIKRVysLFLDEsRSTQYMKEyQDAFL |
| Q9Y2B0 | S115 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2T7 | S137 | Sugiyama | YBX2 CSDA3 MSY2 | EDVFVHQtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEA |
| Q9Y383 | S176 | Sugiyama | LUC7L2 CGI-59 CGI-74 | MDEVEKARAKKREAEEVyRNsMPASsFQQQKLRVCEVCSAY |
| Q9Y3U8 | S91 | Sugiyama | RPL36 | KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______ |
| Q9Y5M8 | S257 | Sugiyama | SRPRB PSEC0230 | LPLKVEFLECSAKGGRGDVGsADIQDLEKWLAKIA______ |
| Q9Y608 | S18 | Sugiyama | LRRFIP2 | ___MGTPASGRKRTPVKDRFsAEDEALsNIAREAEARLAAK |
| Q9Y6X8 | S575 | Sugiyama | ZHX2 AFR1 KIAA0854 RAF | TQAELDRLRVETKLSRREIDsWFSERRKLRDSMEQAVLDSM |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| HSF1-dependent transactivation | R-HSA-3371571 | 1.441547e-08 | 7.841 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 1.778066e-08 | 7.750 | 1 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.525181e-07 | 6.598 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 6.044676e-07 | 6.219 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 7.632974e-06 | 5.117 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 8.124110e-06 | 5.090 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 2.134760e-05 | 4.671 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 1.935391e-05 | 4.713 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 2.069019e-05 | 4.684 | 1 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 2.291359e-05 | 4.640 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 3.138252e-05 | 4.503 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 3.313505e-05 | 4.480 | 1 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 4.054630e-05 | 4.392 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 4.724059e-05 | 4.326 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 5.230423e-05 | 4.281 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 5.896949e-05 | 4.229 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 6.723736e-05 | 4.172 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 1.126934e-04 | 3.948 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.197643e-04 | 3.922 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.721406e-04 | 3.764 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.678250e-04 | 3.775 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 2.629367e-04 | 3.580 | 1 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 4.025264e-04 | 3.395 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 4.856081e-04 | 3.314 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 4.776533e-04 | 3.321 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 5.661118e-04 | 3.247 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 5.832151e-04 | 3.234 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 5.911576e-04 | 3.228 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 6.048618e-04 | 3.218 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 6.570411e-04 | 3.182 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.234990e-03 | 2.908 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.248851e-03 | 2.903 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.440050e-03 | 2.842 | 1 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 1.496071e-03 | 2.825 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.476650e-03 | 2.831 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.606094e-03 | 2.794 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 1.830731e-03 | 2.737 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 1.930464e-03 | 2.714 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 1.991016e-03 | 2.701 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.126168e-03 | 2.672 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 2.233040e-03 | 2.651 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 2.228048e-03 | 2.652 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 2.482044e-03 | 2.605 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 2.701695e-03 | 2.568 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.729828e-03 | 2.564 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.729828e-03 | 2.564 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.729828e-03 | 2.564 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.734234e-03 | 2.563 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.729828e-03 | 2.564 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 2.723337e-03 | 2.565 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 2.900578e-03 | 2.538 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 2.900526e-03 | 2.538 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 3.080823e-03 | 2.511 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 3.251328e-03 | 2.488 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.209092e-03 | 2.494 | 0 | 0 |
| M Phase | R-HSA-68886 | 3.334809e-03 | 2.477 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 3.644438e-03 | 2.438 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 3.758678e-03 | 2.425 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 3.771873e-03 | 2.423 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 3.743821e-03 | 2.427 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 3.644438e-03 | 2.438 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 3.527957e-03 | 2.452 | 1 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 4.234811e-03 | 2.373 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 4.234811e-03 | 2.373 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 4.206051e-03 | 2.376 | 1 | 1 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 4.520713e-03 | 2.345 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 4.330994e-03 | 2.363 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.722998e-03 | 2.326 | 1 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 4.785998e-03 | 2.320 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 5.020928e-03 | 2.299 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 5.402559e-03 | 2.267 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 5.402559e-03 | 2.267 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 5.433613e-03 | 2.265 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 5.490336e-03 | 2.260 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 5.689904e-03 | 2.245 | 1 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 6.067974e-03 | 2.217 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 6.392806e-03 | 2.194 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 6.392806e-03 | 2.194 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 6.548939e-03 | 2.184 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 6.893921e-03 | 2.162 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 7.338123e-03 | 2.134 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 7.031846e-03 | 2.153 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 7.404490e-03 | 2.131 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 7.404490e-03 | 2.131 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 7.774055e-03 | 2.109 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 7.920072e-03 | 2.101 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 7.509290e-03 | 2.124 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 7.934968e-03 | 2.100 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 8.491274e-03 | 2.071 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 8.669290e-03 | 2.062 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 8.669290e-03 | 2.062 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 9.165606e-03 | 2.038 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 8.924089e-03 | 2.049 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 8.641476e-03 | 2.063 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 9.186268e-03 | 2.037 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 9.186268e-03 | 2.037 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 9.190686e-03 | 2.037 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 9.601562e-03 | 2.018 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 9.738066e-03 | 2.012 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 1.060306e-02 | 1.975 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.073012e-02 | 1.969 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.145255e-02 | 1.941 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.164394e-02 | 1.934 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.413589e-02 | 1.850 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.242549e-02 | 1.906 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 1.329331e-02 | 1.876 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.331362e-02 | 1.876 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.423003e-02 | 1.847 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.407814e-02 | 1.851 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.420859e-02 | 1.847 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.243059e-02 | 1.906 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.242549e-02 | 1.906 | 1 | 1 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 1.323668e-02 | 1.878 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 1.323668e-02 | 1.878 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.326890e-02 | 1.877 | 1 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 1.329331e-02 | 1.876 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 1.362899e-02 | 1.866 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 1.242549e-02 | 1.906 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.286587e-02 | 1.891 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 1.342360e-02 | 1.872 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 1.450508e-02 | 1.838 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 1.450508e-02 | 1.838 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 1.562039e-02 | 1.806 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 1.612996e-02 | 1.792 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.562718e-02 | 1.806 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.578604e-02 | 1.802 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.612996e-02 | 1.792 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.612996e-02 | 1.792 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 1.617414e-02 | 1.791 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.676881e-02 | 1.775 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.684932e-02 | 1.773 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.617414e-02 | 1.791 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.733427e-02 | 1.761 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.744126e-02 | 1.758 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.750505e-02 | 1.757 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.752363e-02 | 1.756 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.874474e-02 | 1.727 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.961657e-02 | 1.707 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 2.235981e-02 | 1.651 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 2.235981e-02 | 1.651 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 2.235981e-02 | 1.651 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.061653e-02 | 1.686 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 2.235981e-02 | 1.651 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.223499e-02 | 1.653 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.151940e-02 | 1.667 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 2.112442e-02 | 1.675 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 2.249904e-02 | 1.648 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 2.249904e-02 | 1.648 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 2.288777e-02 | 1.640 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 2.331076e-02 | 1.632 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 2.343191e-02 | 1.630 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.369768e-02 | 1.625 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 2.664125e-02 | 1.574 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 2.664125e-02 | 1.574 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 2.664125e-02 | 1.574 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 2.585399e-02 | 1.587 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.615876e-02 | 1.582 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 2.524637e-02 | 1.598 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 2.485722e-02 | 1.605 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 2.611461e-02 | 1.583 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 2.524188e-02 | 1.598 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.675322e-02 | 1.573 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 2.716275e-02 | 1.566 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 2.744535e-02 | 1.562 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 2.752902e-02 | 1.560 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.753437e-02 | 1.560 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 2.800172e-02 | 1.553 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 2.859532e-02 | 1.544 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.910628e-02 | 1.536 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 3.167259e-02 | 1.499 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 2.988097e-02 | 1.525 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 3.092009e-02 | 1.510 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 3.185287e-02 | 1.497 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 3.088569e-02 | 1.510 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 3.023876e-02 | 1.519 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 3.185287e-02 | 1.497 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 2.988097e-02 | 1.525 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 2.988097e-02 | 1.525 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 2.871677e-02 | 1.542 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.197395e-02 | 1.495 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 3.238127e-02 | 1.490 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 3.310215e-02 | 1.480 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 3.373042e-02 | 1.472 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 3.373042e-02 | 1.472 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 3.433714e-02 | 1.464 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 3.443695e-02 | 1.463 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 3.448793e-02 | 1.462 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 3.475629e-02 | 1.459 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 3.475629e-02 | 1.459 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 3.475629e-02 | 1.459 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 3.475629e-02 | 1.459 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 3.480707e-02 | 1.458 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 3.500418e-02 | 1.456 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 3.631549e-02 | 1.440 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 3.668439e-02 | 1.436 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.947032e-02 | 1.404 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.985329e-02 | 1.400 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 4.073746e-02 | 1.390 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 4.057305e-02 | 1.392 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 4.193698e-02 | 1.377 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 4.232893e-02 | 1.373 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 4.234526e-02 | 1.373 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 4.373853e-02 | 1.359 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 4.374919e-02 | 1.359 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 4.394213e-02 | 1.357 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 4.425951e-02 | 1.354 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 4.461428e-02 | 1.351 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 4.464575e-02 | 1.350 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 4.464575e-02 | 1.350 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 4.464575e-02 | 1.350 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 4.517037e-02 | 1.345 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.517037e-02 | 1.345 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 5.024208e-02 | 1.299 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 5.024208e-02 | 1.299 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 5.015291e-02 | 1.300 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 5.208197e-02 | 1.283 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 4.770908e-02 | 1.321 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 5.015291e-02 | 1.300 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 5.129926e-02 | 1.290 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 5.208197e-02 | 1.283 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 4.829989e-02 | 1.316 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 4.803984e-02 | 1.318 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 4.589883e-02 | 1.338 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 4.589883e-02 | 1.338 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 4.589883e-02 | 1.338 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 5.129926e-02 | 1.290 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 4.791843e-02 | 1.319 | 1 | 1 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 5.129926e-02 | 1.290 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 4.661923e-02 | 1.331 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 4.829989e-02 | 1.316 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.803984e-02 | 1.318 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 5.259517e-02 | 1.279 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 5.265022e-02 | 1.279 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 5.327187e-02 | 1.274 | 1 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 5.581875e-02 | 1.253 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 5.581875e-02 | 1.253 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 5.581875e-02 | 1.253 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 5.670303e-02 | 1.246 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 5.696126e-02 | 1.244 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 5.796467e-02 | 1.237 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 5.796467e-02 | 1.237 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 5.796467e-02 | 1.237 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 5.916333e-02 | 1.228 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 5.916333e-02 | 1.228 | 0 | 0 |
| Defective Base Excision Repair Associated with OGG1 | R-HSA-9656249 | 6.014046e-02 | 1.221 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 6.014046e-02 | 1.221 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 6.014046e-02 | 1.221 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 6.634173e-02 | 1.178 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 6.634173e-02 | 1.178 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 6.634173e-02 | 1.178 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 7.106002e-02 | 1.148 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 7.134985e-02 | 1.147 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 7.084690e-02 | 1.150 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 6.450155e-02 | 1.190 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 6.368171e-02 | 1.196 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 6.524913e-02 | 1.185 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 6.572885e-02 | 1.182 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 6.132807e-02 | 1.212 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 6.598259e-02 | 1.181 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 6.598259e-02 | 1.181 | 0 | 0 |
| Kinesins | R-HSA-983189 | 7.084690e-02 | 1.150 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 7.146476e-02 | 1.146 | 1 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 7.042532e-02 | 1.152 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 7.106002e-02 | 1.148 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 6.789068e-02 | 1.168 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 7.179587e-02 | 1.144 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 7.253183e-02 | 1.139 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 7.402186e-02 | 1.131 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 7.440173e-02 | 1.128 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 7.501383e-02 | 1.125 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 7.588556e-02 | 1.120 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 7.588556e-02 | 1.120 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 7.588556e-02 | 1.120 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 7.588556e-02 | 1.120 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 7.588556e-02 | 1.120 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 7.645865e-02 | 1.117 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 7.645865e-02 | 1.117 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 7.645865e-02 | 1.117 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 7.645865e-02 | 1.117 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 7.645865e-02 | 1.117 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 7.680912e-02 | 1.115 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 7.680912e-02 | 1.115 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 7.705036e-02 | 1.113 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 7.749995e-02 | 1.111 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 7.834582e-02 | 1.106 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 7.834582e-02 | 1.106 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 7.891635e-02 | 1.103 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 7.896283e-02 | 1.103 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 7.913837e-02 | 1.102 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 9.020485e-02 | 1.045 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 9.471425e-02 | 1.024 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 9.471425e-02 | 1.024 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 9.471425e-02 | 1.024 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 9.186342e-02 | 1.037 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 8.647657e-02 | 1.063 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 8.027706e-02 | 1.095 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 9.531683e-02 | 1.021 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 9.531683e-02 | 1.021 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 8.585073e-02 | 1.066 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.198210e-02 | 1.036 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 9.198210e-02 | 1.036 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 9.198210e-02 | 1.036 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 9.239755e-02 | 1.034 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 8.228321e-02 | 1.085 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 8.222231e-02 | 1.085 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 8.222231e-02 | 1.085 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 8.222231e-02 | 1.085 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 8.579873e-02 | 1.067 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 8.647657e-02 | 1.063 | 0 | 0 |
| S Phase | R-HSA-69242 | 8.059750e-02 | 1.094 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 9.120233e-02 | 1.040 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 8.477686e-02 | 1.072 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 8.788939e-02 | 1.056 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 8.027706e-02 | 1.095 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 9.471425e-02 | 1.024 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 9.635574e-02 | 1.016 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 9.635574e-02 | 1.016 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 9.669365e-02 | 1.015 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 9.669365e-02 | 1.015 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.691925e-02 | 1.014 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 9.828288e-02 | 1.008 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 9.828288e-02 | 1.008 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.020757e-01 | 0.991 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.041211e-01 | 0.982 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.070985e-01 | 0.970 | 1 | 1 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 1.071700e-01 | 0.970 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.076539e-01 | 0.968 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 1.076539e-01 | 0.968 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 1.087327e-01 | 0.964 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.087327e-01 | 0.964 | 1 | 1 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.087327e-01 | 0.964 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 1.087327e-01 | 0.964 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.095999e-01 | 0.960 | 1 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 1.233036e-01 | 0.909 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 1.233036e-01 | 0.909 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 1.233036e-01 | 0.909 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 1.233036e-01 | 0.909 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 1.233036e-01 | 0.909 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 1.233036e-01 | 0.909 | 0 | 0 |
| Defective OGG1 Substrate Binding | R-HSA-9656255 | 1.233036e-01 | 0.909 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 1.233036e-01 | 0.909 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 1.233036e-01 | 0.909 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.233036e-01 | 0.909 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 1.233036e-01 | 0.909 | 0 | 0 |
| Defective OGG1 Localization | R-HSA-9657050 | 1.233036e-01 | 0.909 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 1.170801e-01 | 0.932 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 1.170801e-01 | 0.932 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 1.170801e-01 | 0.932 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 1.381048e-01 | 0.860 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 1.381048e-01 | 0.860 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.381048e-01 | 0.860 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 1.269908e-01 | 0.896 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.269908e-01 | 0.896 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 1.269908e-01 | 0.896 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 1.320061e-01 | 0.879 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 1.315621e-01 | 0.881 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.134725e-01 | 0.945 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.335771e-01 | 0.874 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 1.217519e-01 | 0.915 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 1.178788e-01 | 0.929 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.249432e-01 | 0.903 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.132770e-01 | 0.946 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.242838e-01 | 0.906 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 1.178654e-01 | 0.929 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.200242e-01 | 0.921 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.200242e-01 | 0.921 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.200242e-01 | 0.921 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.200242e-01 | 0.921 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.153360e-01 | 0.938 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.335797e-01 | 0.874 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.215517e-01 | 0.915 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 1.335100e-01 | 0.874 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.200242e-01 | 0.921 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.281630e-01 | 0.892 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 1.211116e-01 | 0.917 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.200242e-01 | 0.921 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 1.256809e-01 | 0.901 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 1.188991e-01 | 0.925 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 1.232933e-01 | 0.909 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.335797e-01 | 0.874 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.292105e-01 | 0.889 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.292105e-01 | 0.889 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.188991e-01 | 0.925 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 1.192879e-01 | 0.923 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 1.386971e-01 | 0.858 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 1.413104e-01 | 0.850 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 1.438378e-01 | 0.842 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.443153e-01 | 0.841 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.443153e-01 | 0.841 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.444780e-01 | 0.840 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.452078e-01 | 0.838 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 1.465162e-01 | 0.834 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 1.465162e-01 | 0.834 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.465162e-01 | 0.834 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.465162e-01 | 0.834 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.465162e-01 | 0.834 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 1.465162e-01 | 0.834 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 1.465450e-01 | 0.834 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.472712e-01 | 0.832 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 1.472712e-01 | 0.832 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 1.472712e-01 | 0.832 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 1.491071e-01 | 0.827 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 1.491071e-01 | 0.827 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.491071e-01 | 0.827 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 1.491071e-01 | 0.827 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 1.491071e-01 | 0.827 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.491071e-01 | 0.827 | 0 | 0 |
| Defective OGG1 Substrate Processing | R-HSA-9656256 | 2.314096e-01 | 0.636 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.314096e-01 | 0.636 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.314096e-01 | 0.636 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.314096e-01 | 0.636 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.314096e-01 | 0.636 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.314096e-01 | 0.636 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.314096e-01 | 0.636 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.314096e-01 | 0.636 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.314096e-01 | 0.636 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.874397e-01 | 0.727 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.874397e-01 | 0.727 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.874397e-01 | 0.727 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.874397e-01 | 0.727 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 1.874397e-01 | 0.727 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 1.874397e-01 | 0.727 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 1.874397e-01 | 0.727 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 1.874397e-01 | 0.727 | 0 | 0 |
| PI and PC transport between ER and Golgi membranes | R-HSA-1483196 | 3.261906e-01 | 0.487 | 0 | 0 |
| Mitochondrial transcription initiation | R-HSA-163282 | 3.261906e-01 | 0.487 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 3.261906e-01 | 0.487 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 3.261906e-01 | 0.487 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5619101 | 3.261906e-01 | 0.487 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 3.261906e-01 | 0.487 | 0 | 0 |
| Defective MMADHC causes MMAHCD | R-HSA-3359473 | 3.261906e-01 | 0.487 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 3.261906e-01 | 0.487 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.261906e-01 | 0.487 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 3.261906e-01 | 0.487 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 3.261906e-01 | 0.487 | 0 | 0 |
| Intestinal infectious diseases | R-HSA-8942233 | 3.261906e-01 | 0.487 | 0 | 0 |
| MyD88 deficiency (TLR5) | R-HSA-5602680 | 3.261906e-01 | 0.487 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.261906e-01 | 0.487 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 3.261906e-01 | 0.487 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5660686 | 3.261906e-01 | 0.487 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 3.261906e-01 | 0.487 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 3.261906e-01 | 0.487 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 3.261906e-01 | 0.487 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 2.352525e-01 | 0.628 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.352525e-01 | 0.628 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 2.352525e-01 | 0.628 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 2.352525e-01 | 0.628 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 1.780467e-01 | 0.749 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.623035e-01 | 0.790 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.623035e-01 | 0.790 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.623035e-01 | 0.790 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.623035e-01 | 0.790 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.623035e-01 | 0.790 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.623035e-01 | 0.790 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.112105e-01 | 0.675 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.836329e-01 | 0.547 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 2.836329e-01 | 0.547 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 2.836329e-01 | 0.547 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 2.836329e-01 | 0.547 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.092881e-01 | 0.388 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 4.092881e-01 | 0.388 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.092881e-01 | 0.388 | 0 | 0 |
| Interaction between PHLDA1 and AURKA | R-HSA-8854521 | 4.092881e-01 | 0.388 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.092881e-01 | 0.388 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.092881e-01 | 0.388 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 4.092881e-01 | 0.388 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.092881e-01 | 0.388 | 0 | 0 |
| HHAT G278V doesn't palmitoylate Hh-Np | R-HSA-5658034 | 4.092881e-01 | 0.388 | 0 | 0 |
| Defective DHDDS causes RP59 | R-HSA-4755609 | 4.092881e-01 | 0.388 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.092881e-01 | 0.388 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 4.092881e-01 | 0.388 | 0 | 0 |
| TWIK related potassium channel (TREK) | R-HSA-1299503 | 4.092881e-01 | 0.388 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 4.092881e-01 | 0.388 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.878983e-01 | 0.726 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.455665e-01 | 0.610 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 2.455665e-01 | 0.610 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 3.317145e-01 | 0.479 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 1.891045e-01 | 0.723 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.807030e-01 | 0.552 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 2.807030e-01 | 0.552 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 2.807030e-01 | 0.552 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 2.807030e-01 | 0.552 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 2.424072e-01 | 0.615 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 2.118667e-01 | 0.674 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.620667e-01 | 0.790 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 2.354449e-01 | 0.628 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 2.354449e-01 | 0.628 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 2.354449e-01 | 0.628 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 2.354449e-01 | 0.628 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 2.354449e-01 | 0.628 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 2.354449e-01 | 0.628 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 3.162442e-01 | 0.500 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 3.162442e-01 | 0.500 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 3.788356e-01 | 0.422 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 3.788356e-01 | 0.422 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 3.788356e-01 | 0.422 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 3.788356e-01 | 0.422 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 3.788356e-01 | 0.422 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis | R-HSA-9632974 | 3.788356e-01 | 0.422 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 4.821419e-01 | 0.317 | 0 | 0 |
| Defective MMACHC causes MAHCC | R-HSA-3359474 | 4.821419e-01 | 0.317 | 0 | 0 |
| Signaling by plasma membrane FGFR1 fusions | R-HSA-8853336 | 4.821419e-01 | 0.317 | 0 | 0 |
| Defective GCLC causes HAGGSD | R-HSA-5578999 | 4.821419e-01 | 0.317 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.821419e-01 | 0.317 | 0 | 0 |
| Defective ABCA1 causes TGD | R-HSA-5682113 | 4.821419e-01 | 0.317 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 4.821419e-01 | 0.317 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 4.821419e-01 | 0.317 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.821419e-01 | 0.317 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 4.821419e-01 | 0.317 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 1.721235e-01 | 0.764 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 2.998963e-01 | 0.523 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 1.867985e-01 | 0.729 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 2.485093e-01 | 0.605 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 3.518531e-01 | 0.454 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 3.518531e-01 | 0.454 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 2.377073e-01 | 0.624 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.019998e-01 | 0.695 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 2.703101e-01 | 0.568 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.703101e-01 | 0.568 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.703101e-01 | 0.568 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 3.292397e-01 | 0.482 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 4.245022e-01 | 0.372 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 4.245022e-01 | 0.372 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 4.245022e-01 | 0.372 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 4.245022e-01 | 0.372 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 4.245022e-01 | 0.372 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 2.572074e-01 | 0.590 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.925523e-01 | 0.534 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.925523e-01 | 0.534 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 2.925523e-01 | 0.534 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 3.872332e-01 | 0.412 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 3.872332e-01 | 0.412 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 2.816543e-01 | 0.550 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 2.207257e-01 | 0.656 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 3.379934e-01 | 0.471 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.379934e-01 | 0.471 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 3.881830e-01 | 0.411 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 3.881830e-01 | 0.411 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 4.683566e-01 | 0.329 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 4.683566e-01 | 0.329 | 0 | 0 |
| Alternative complement activation | R-HSA-173736 | 5.460142e-01 | 0.263 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.460142e-01 | 0.263 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 5.460142e-01 | 0.263 | 0 | 0 |
| MPS VI - Maroteaux-Lamy syndrome | R-HSA-2206285 | 5.460142e-01 | 0.263 | 0 | 0 |
| Signaling by LRP5 mutants | R-HSA-5339717 | 5.460142e-01 | 0.263 | 0 | 0 |
| Defective MAT1A causes MATD | R-HSA-5579024 | 5.460142e-01 | 0.263 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 5.460142e-01 | 0.263 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 5.460142e-01 | 0.263 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 2.153513e-01 | 0.667 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 2.356772e-01 | 0.628 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 3.195207e-01 | 0.496 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 3.866669e-01 | 0.413 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.738219e-01 | 0.760 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 4.563184e-01 | 0.341 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 4.563184e-01 | 0.341 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 4.563184e-01 | 0.341 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 4.563184e-01 | 0.341 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.606388e-01 | 0.794 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 5.101512e-01 | 0.292 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 5.101512e-01 | 0.292 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 5.101512e-01 | 0.292 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 3.928311e-01 | 0.406 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 4.302481e-01 | 0.366 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 4.896238e-01 | 0.310 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 4.896238e-01 | 0.310 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 4.896238e-01 | 0.310 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 4.233875e-01 | 0.373 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 4.748461e-01 | 0.323 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 4.112303e-01 | 0.386 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 4.630637e-01 | 0.334 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 4.630637e-01 | 0.334 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 4.630637e-01 | 0.334 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 4.653680e-01 | 0.332 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 4.879511e-01 | 0.312 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 4.879511e-01 | 0.312 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 4.879511e-01 | 0.312 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 5.218960e-01 | 0.282 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 5.218960e-01 | 0.282 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 5.218960e-01 | 0.282 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 5.218960e-01 | 0.282 | 0 | 0 |
| Presynaptic depolarization and calcium channel opening | R-HSA-112308 | 5.497271e-01 | 0.260 | 0 | 0 |
| Activation of AMPA receptors | R-HSA-399710 | 6.020118e-01 | 0.220 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 6.020118e-01 | 0.220 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 6.020118e-01 | 0.220 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 6.020118e-01 | 0.220 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 6.020118e-01 | 0.220 | 0 | 0 |
| Defective SLC1A3 causes episodic ataxia 6 (EA6) | R-HSA-5619062 | 6.020118e-01 | 0.220 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 6.020118e-01 | 0.220 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 6.020118e-01 | 0.220 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 4.981645e-01 | 0.303 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 4.948062e-01 | 0.306 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 5.299577e-01 | 0.276 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 5.564232e-01 | 0.255 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 5.869959e-01 | 0.231 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 5.869959e-01 | 0.231 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 5.869959e-01 | 0.231 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 5.085215e-01 | 0.294 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 5.630603e-01 | 0.249 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 5.829012e-01 | 0.234 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 5.662157e-01 | 0.247 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 5.825935e-01 | 0.235 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 5.825935e-01 | 0.235 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 6.136752e-01 | 0.212 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 6.114808e-01 | 0.214 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.114808e-01 | 0.214 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 6.219245e-01 | 0.206 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 6.219245e-01 | 0.206 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 5.424753e-01 | 0.266 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 5.305456e-01 | 0.275 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 4.981645e-01 | 0.303 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.610126e-01 | 0.442 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 5.825935e-01 | 0.235 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 3.379934e-01 | 0.471 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 3.195207e-01 | 0.496 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 2.395736e-01 | 0.621 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 2.982014e-01 | 0.525 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 2.816543e-01 | 0.550 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 2.076430e-01 | 0.683 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 5.825935e-01 | 0.235 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 3.816946e-01 | 0.418 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 4.233875e-01 | 0.373 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 4.233875e-01 | 0.373 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.673431e-01 | 0.573 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.338408e-01 | 0.631 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 5.124128e-01 | 0.290 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 3.098337e-01 | 0.509 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 4.630637e-01 | 0.334 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.791416e-01 | 0.747 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 2.500241e-01 | 0.602 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.658225e-01 | 0.780 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 5.597904e-01 | 0.252 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 5.853443e-01 | 0.233 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 6.068327e-01 | 0.217 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 6.219245e-01 | 0.206 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 3.778240e-01 | 0.423 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 3.778240e-01 | 0.423 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 5.582424e-01 | 0.253 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 5.620812e-01 | 0.250 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 2.816543e-01 | 0.550 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 2.876181e-01 | 0.541 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 5.837895e-01 | 0.234 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 2.708323e-01 | 0.567 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 4.585230e-01 | 0.339 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 5.597904e-01 | 0.252 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 6.068327e-01 | 0.217 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.905985e-01 | 0.720 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 3.334090e-01 | 0.477 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 4.302481e-01 | 0.366 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 4.843759e-01 | 0.315 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 2.604721e-01 | 0.584 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 4.380879e-01 | 0.358 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.112105e-01 | 0.675 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.455665e-01 | 0.610 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.455665e-01 | 0.610 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 2.066002e-01 | 0.685 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 1.726161e-01 | 0.763 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 4.072201e-01 | 0.390 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 5.837895e-01 | 0.234 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 5.909021e-01 | 0.228 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 5.909021e-01 | 0.228 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 1.991800e-01 | 0.701 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 3.587269e-01 | 0.445 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.272422e-01 | 0.644 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 2.112105e-01 | 0.675 | 0 | 0 |
| Formation of lateral plate mesoderm | R-HSA-9758920 | 2.836329e-01 | 0.547 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 2.836329e-01 | 0.547 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 2.455665e-01 | 0.610 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 2.455665e-01 | 0.610 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 1.672888e-01 | 0.777 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.788356e-01 | 0.422 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 2.631824e-01 | 0.580 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 2.371796e-01 | 0.625 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 2.114417e-01 | 0.675 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 5.027380e-01 | 0.299 | 0 | 0 |
| Activation of C3 and C5 | R-HSA-174577 | 6.020118e-01 | 0.220 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 5.530182e-01 | 0.257 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.881610e-01 | 0.540 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 2.974632e-01 | 0.527 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 4.500375e-01 | 0.347 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 3.881830e-01 | 0.411 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 4.378281e-01 | 0.359 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.504044e-01 | 0.601 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 2.485093e-01 | 0.605 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 4.981645e-01 | 0.303 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 2.277221e-01 | 0.643 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 1.780467e-01 | 0.749 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 2.112105e-01 | 0.675 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 2.146726e-01 | 0.668 | 0 | 0 |
| PKA activation | R-HSA-163615 | 1.891045e-01 | 0.723 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 2.424072e-01 | 0.615 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 4.245022e-01 | 0.372 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.957592e-01 | 0.708 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 4.683566e-01 | 0.329 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 4.174483e-01 | 0.379 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 6.219245e-01 | 0.206 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 6.219245e-01 | 0.206 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 6.219245e-01 | 0.206 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 4.531263e-01 | 0.344 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 2.807030e-01 | 0.552 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 4.170690e-01 | 0.380 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 5.825935e-01 | 0.235 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 4.170849e-01 | 0.380 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 2.604721e-01 | 0.584 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 3.351823e-01 | 0.475 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.623035e-01 | 0.790 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 2.455665e-01 | 0.610 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 2.455665e-01 | 0.610 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.597058e-01 | 0.586 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 2.469425e-01 | 0.607 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 6.219245e-01 | 0.206 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 4.762553e-01 | 0.322 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 2.845158e-01 | 0.546 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 4.990152e-01 | 0.302 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 3.006643e-01 | 0.522 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 4.079720e-01 | 0.389 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 2.377073e-01 | 0.624 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 5.310542e-01 | 0.275 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 5.765828e-01 | 0.239 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 3.488196e-01 | 0.457 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.592275e-01 | 0.798 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 1.874397e-01 | 0.727 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 2.836329e-01 | 0.547 | 0 | 0 |
| Transcription from mitochondrial promoters | R-HSA-75944 | 4.092881e-01 | 0.388 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 2.146726e-01 | 0.668 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 2.146726e-01 | 0.668 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 3.317145e-01 | 0.479 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 3.788356e-01 | 0.422 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 2.272422e-01 | 0.644 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 2.771488e-01 | 0.557 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.639017e-01 | 0.785 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 4.683566e-01 | 0.329 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 4.683566e-01 | 0.329 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 4.683566e-01 | 0.329 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 4.683566e-01 | 0.329 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.778536e-01 | 0.750 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.563184e-01 | 0.341 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 2.585396e-01 | 0.587 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 3.759834e-01 | 0.425 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 5.497271e-01 | 0.260 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 6.020118e-01 | 0.220 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 5.530182e-01 | 0.257 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 5.820664e-01 | 0.235 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.077363e-01 | 0.216 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 2.882704e-01 | 0.540 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 2.032362e-01 | 0.692 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 4.263129e-01 | 0.370 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 4.981645e-01 | 0.303 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 4.302481e-01 | 0.366 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 5.124128e-01 | 0.290 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 4.577773e-01 | 0.339 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 4.233875e-01 | 0.373 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 3.799743e-01 | 0.420 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 2.084924e-01 | 0.681 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 3.659135e-01 | 0.437 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 6.216807e-01 | 0.206 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 4.563184e-01 | 0.341 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 4.898116e-01 | 0.310 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 1.632450e-01 | 0.787 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.639017e-01 | 0.785 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 1.874397e-01 | 0.727 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.424072e-01 | 0.615 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 2.102459e-01 | 0.677 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 4.245022e-01 | 0.372 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 4.221276e-01 | 0.375 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 3.599586e-01 | 0.444 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 3.841156e-01 | 0.416 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 5.101512e-01 | 0.292 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 5.869959e-01 | 0.231 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 4.115677e-01 | 0.386 | 1 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 4.233875e-01 | 0.373 | 1 | 1 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 2.708323e-01 | 0.567 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.684549e-01 | 0.774 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 5.551084e-01 | 0.256 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 3.352587e-01 | 0.475 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 3.866669e-01 | 0.413 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 5.630809e-01 | 0.249 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 3.150268e-01 | 0.502 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 5.481794e-01 | 0.261 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 3.867101e-01 | 0.413 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 2.112105e-01 | 0.675 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 4.366836e-01 | 0.360 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 5.218960e-01 | 0.282 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 5.202036e-01 | 0.284 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 5.777449e-01 | 0.238 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 6.040028e-01 | 0.219 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.864301e-01 | 0.729 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 2.424072e-01 | 0.615 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 3.788356e-01 | 0.422 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 4.683566e-01 | 0.329 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.998963e-01 | 0.523 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 5.564232e-01 | 0.255 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 4.879511e-01 | 0.312 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 3.881830e-01 | 0.411 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 5.027380e-01 | 0.299 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 3.665676e-01 | 0.436 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 4.627284e-01 | 0.335 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 2.061342e-01 | 0.686 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 6.017269e-01 | 0.221 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.631824e-01 | 0.580 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 1.655369e-01 | 0.781 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 2.310893e-01 | 0.636 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 2.310893e-01 | 0.636 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 5.837895e-01 | 0.234 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 4.916483e-01 | 0.308 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.314096e-01 | 0.636 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 2.314096e-01 | 0.636 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 3.261906e-01 | 0.487 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.261906e-01 | 0.487 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 3.261906e-01 | 0.487 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.780467e-01 | 0.749 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 4.092881e-01 | 0.388 | 0 | 0 |
| Defective ABCC8 can cause hypo- and hyper-glycemias | R-HSA-5683177 | 4.092881e-01 | 0.388 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 4.092881e-01 | 0.388 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.092881e-01 | 0.388 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 3.317145e-01 | 0.479 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 3.317145e-01 | 0.479 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 1.891045e-01 | 0.723 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.675449e-01 | 0.776 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 2.807030e-01 | 0.552 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 2.354449e-01 | 0.628 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 3.162442e-01 | 0.500 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 3.162442e-01 | 0.500 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 3.788356e-01 | 0.422 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 3.788356e-01 | 0.422 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 4.821419e-01 | 0.317 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 4.821419e-01 | 0.317 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 2.597058e-01 | 0.586 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 2.485093e-01 | 0.605 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.518531e-01 | 0.454 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 1.610009e-01 | 0.793 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.245022e-01 | 0.372 | 0 | 0 |
| Transmission across Electrical Synapses | R-HSA-112307 | 5.460142e-01 | 0.263 | 0 | 0 |
| Electric Transmission Across Gap Junctions | R-HSA-112303 | 5.460142e-01 | 0.263 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 5.460142e-01 | 0.263 | 0 | 0 |
| Alanine metabolism | R-HSA-8964540 | 5.460142e-01 | 0.263 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 5.460142e-01 | 0.263 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 5.460142e-01 | 0.263 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 5.460142e-01 | 0.263 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.937582e-01 | 0.713 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 5.101512e-01 | 0.292 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 4.378281e-01 | 0.359 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 4.531263e-01 | 0.344 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 4.879511e-01 | 0.312 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 5.027380e-01 | 0.299 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 5.218960e-01 | 0.282 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 5.218960e-01 | 0.282 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 5.497271e-01 | 0.260 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 5.497271e-01 | 0.260 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 6.020118e-01 | 0.220 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 6.020118e-01 | 0.220 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 5.363794e-01 | 0.271 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 5.052792e-01 | 0.296 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 5.021082e-01 | 0.299 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 5.468207e-01 | 0.262 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 6.043061e-01 | 0.219 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 6.040473e-01 | 0.219 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 6.062921e-01 | 0.217 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 3.191358e-01 | 0.496 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 5.825935e-01 | 0.235 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 4.378281e-01 | 0.359 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 5.829012e-01 | 0.234 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 3.389360e-01 | 0.470 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 4.561989e-01 | 0.341 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 2.925523e-01 | 0.534 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 2.424072e-01 | 0.615 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 5.837895e-01 | 0.234 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 2.175669e-01 | 0.662 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 6.065129e-01 | 0.217 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.845158e-01 | 0.546 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 4.245022e-01 | 0.372 | 0 | 0 |
| MDK and PTN in ALK signaling | R-HSA-9851151 | 5.460142e-01 | 0.263 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 5.218960e-01 | 0.282 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.117636e-01 | 0.674 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 3.956657e-01 | 0.403 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 3.647483e-01 | 0.438 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 5.829012e-01 | 0.234 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.910143e-01 | 0.408 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 4.132173e-01 | 0.384 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 2.352525e-01 | 0.628 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 3.317145e-01 | 0.479 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.424072e-01 | 0.615 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 4.683566e-01 | 0.329 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 4.683566e-01 | 0.329 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 4.057454e-01 | 0.392 | 0 | 0 |
| LGI-ADAM interactions | R-HSA-5682910 | 5.497271e-01 | 0.260 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 4.513008e-01 | 0.346 | 1 | 1 |
| Carnitine shuttle | R-HSA-200425 | 5.299577e-01 | 0.276 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 6.065129e-01 | 0.217 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 6.219245e-01 | 0.206 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 6.219245e-01 | 0.206 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 6.219245e-01 | 0.206 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.665702e-01 | 0.778 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 5.987765e-01 | 0.223 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 5.268051e-01 | 0.278 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.580070e-01 | 0.801 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 2.336871e-01 | 0.631 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 4.683566e-01 | 0.329 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 5.820664e-01 | 0.235 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 6.219245e-01 | 0.206 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 3.881830e-01 | 0.411 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 4.751404e-01 | 0.323 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 2.572074e-01 | 0.590 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 4.252853e-01 | 0.371 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 5.065942e-01 | 0.295 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 5.530182e-01 | 0.257 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 6.040028e-01 | 0.219 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 4.185195e-01 | 0.378 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.378281e-01 | 0.359 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 4.861002e-01 | 0.313 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.261906e-01 | 0.487 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 4.092881e-01 | 0.388 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 4.092881e-01 | 0.388 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 4.092881e-01 | 0.388 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 2.455665e-01 | 0.610 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 4.821419e-01 | 0.317 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 2.274267e-01 | 0.643 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 4.245022e-01 | 0.372 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 2.771488e-01 | 0.557 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 3.609392e-01 | 0.443 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 5.460142e-01 | 0.263 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 3.388079e-01 | 0.470 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 5.101512e-01 | 0.292 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.896238e-01 | 0.310 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 4.896238e-01 | 0.310 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 3.544460e-01 | 0.450 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 5.218960e-01 | 0.282 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 5.497271e-01 | 0.260 | 0 | 0 |
| Biosynthesis of DPAn-3-derived 13-series resolvins | R-HSA-9026403 | 6.020118e-01 | 0.220 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 6.020118e-01 | 0.220 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 4.005720e-01 | 0.397 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 4.299820e-01 | 0.367 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 5.564232e-01 | 0.255 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 1.997968e-01 | 0.699 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 3.881830e-01 | 0.411 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 5.838568e-01 | 0.234 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 4.821419e-01 | 0.317 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 3.587269e-01 | 0.445 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 4.563184e-01 | 0.341 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 5.299577e-01 | 0.276 | 0 | 0 |
| Diseases of Base Excision Repair | R-HSA-9605308 | 2.836329e-01 | 0.547 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 1.672888e-01 | 0.777 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 3.379934e-01 | 0.471 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 2.352525e-01 | 0.628 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 3.788356e-01 | 0.422 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 3.788356e-01 | 0.422 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 4.821419e-01 | 0.317 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 4.245022e-01 | 0.372 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 4.245022e-01 | 0.372 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.460142e-01 | 0.263 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 5.460142e-01 | 0.263 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 5.299577e-01 | 0.276 | 0 | 0 |
| Estrogen biosynthesis | R-HSA-193144 | 6.219245e-01 | 0.206 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 6.219245e-01 | 0.206 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 6.219245e-01 | 0.206 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 3.853079e-01 | 0.414 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.836329e-01 | 0.547 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 5.497271e-01 | 0.260 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 5.124128e-01 | 0.290 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 2.572074e-01 | 0.590 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 3.587269e-01 | 0.445 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 5.363794e-01 | 0.271 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 6.219245e-01 | 0.206 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 4.524029e-01 | 0.344 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 3.872332e-01 | 0.412 | 1 | 1 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 6.047444e-01 | 0.218 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 6.047444e-01 | 0.218 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 6.114808e-01 | 0.214 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 6.219245e-01 | 0.206 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 6.052288e-01 | 0.218 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 5.829012e-01 | 0.234 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 5.101512e-01 | 0.292 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 3.587269e-01 | 0.445 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 5.027380e-01 | 0.299 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 6.222982e-01 | 0.206 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 6.222982e-01 | 0.206 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 6.223420e-01 | 0.206 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 6.236692e-01 | 0.205 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 6.243814e-01 | 0.205 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 6.262066e-01 | 0.203 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.262066e-01 | 0.203 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 6.301783e-01 | 0.201 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 6.306796e-01 | 0.200 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 6.368322e-01 | 0.196 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 6.369908e-01 | 0.196 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 6.371008e-01 | 0.196 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 6.387149e-01 | 0.195 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 6.387149e-01 | 0.195 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 6.387149e-01 | 0.195 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 6.469505e-01 | 0.189 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 6.500918e-01 | 0.187 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 6.500918e-01 | 0.187 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 6.506397e-01 | 0.187 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.511051e-01 | 0.186 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.511051e-01 | 0.186 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.511051e-01 | 0.186 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.511051e-01 | 0.186 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.511051e-01 | 0.186 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.511051e-01 | 0.186 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 6.511051e-01 | 0.186 | 0 | 0 |
| Phase 1 - inactivation of fast Na+ channels | R-HSA-5576894 | 6.511051e-01 | 0.186 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 6.511051e-01 | 0.186 | 0 | 0 |
| NGF-independant TRKA activation | R-HSA-187024 | 6.511051e-01 | 0.186 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.511051e-01 | 0.186 | 0 | 0 |
| Formation of the Editosome | R-HSA-75094 | 6.511051e-01 | 0.186 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 6.511051e-01 | 0.186 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 6.511051e-01 | 0.186 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.511051e-01 | 0.186 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 6.511051e-01 | 0.186 | 0 | 0 |
| Acetylcholine inhibits contraction of outer hair cells | R-HSA-9667769 | 6.511051e-01 | 0.186 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 6.511051e-01 | 0.186 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 6.511051e-01 | 0.186 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 6.511051e-01 | 0.186 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 6.511051e-01 | 0.186 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 6.515117e-01 | 0.186 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 6.535760e-01 | 0.185 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 6.535760e-01 | 0.185 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 6.535760e-01 | 0.185 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 6.545232e-01 | 0.184 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 6.545232e-01 | 0.184 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 6.545232e-01 | 0.184 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 6.545232e-01 | 0.184 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 6.545232e-01 | 0.184 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 6.546471e-01 | 0.184 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 6.612618e-01 | 0.180 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 6.645800e-01 | 0.177 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 6.645800e-01 | 0.177 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 6.645800e-01 | 0.177 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 6.645800e-01 | 0.177 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 6.669535e-01 | 0.176 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 6.669535e-01 | 0.176 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 6.678112e-01 | 0.175 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 6.741301e-01 | 0.171 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 6.741301e-01 | 0.171 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 6.755007e-01 | 0.170 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 6.791501e-01 | 0.168 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 6.848353e-01 | 0.164 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 6.848353e-01 | 0.164 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 6.848353e-01 | 0.164 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 6.848353e-01 | 0.164 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 6.848353e-01 | 0.164 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 6.848353e-01 | 0.164 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 6.848353e-01 | 0.164 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 6.848353e-01 | 0.164 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 6.848353e-01 | 0.164 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 6.858721e-01 | 0.164 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 6.861993e-01 | 0.164 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 6.890692e-01 | 0.162 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 6.890692e-01 | 0.162 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 6.890692e-01 | 0.162 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 6.890692e-01 | 0.162 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 6.934891e-01 | 0.159 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 6.941451e-01 | 0.159 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 6.941451e-01 | 0.159 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 6.941451e-01 | 0.159 | 0 | 0 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors | R-HSA-629587 | 6.941451e-01 | 0.159 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 6.941451e-01 | 0.159 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 6.941451e-01 | 0.159 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 6.941451e-01 | 0.159 | 0 | 0 |
| Lipid particle organization | R-HSA-8964572 | 6.941451e-01 | 0.159 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 6.964149e-01 | 0.157 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 6.964149e-01 | 0.157 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 6.964149e-01 | 0.157 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 6.964419e-01 | 0.157 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 6.964419e-01 | 0.157 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 6.967001e-01 | 0.157 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 7.046772e-01 | 0.152 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 7.046772e-01 | 0.152 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 7.046772e-01 | 0.152 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 7.049226e-01 | 0.152 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 7.121895e-01 | 0.147 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 7.121895e-01 | 0.147 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 7.121895e-01 | 0.147 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.121895e-01 | 0.147 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 7.121895e-01 | 0.147 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 7.129288e-01 | 0.147 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 7.129288e-01 | 0.147 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 7.129288e-01 | 0.147 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 7.129288e-01 | 0.147 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 7.129288e-01 | 0.147 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.129288e-01 | 0.147 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 7.129288e-01 | 0.147 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 7.129288e-01 | 0.147 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 7.129288e-01 | 0.147 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 7.129288e-01 | 0.147 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 7.141105e-01 | 0.146 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 7.152682e-01 | 0.146 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 7.163961e-01 | 0.145 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 7.165451e-01 | 0.145 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 7.196711e-01 | 0.143 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 7.223819e-01 | 0.141 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 7.263425e-01 | 0.139 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 7.269367e-01 | 0.139 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 7.292630e-01 | 0.137 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 7.292630e-01 | 0.137 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 7.308675e-01 | 0.136 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 7.318779e-01 | 0.136 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 7.318779e-01 | 0.136 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 7.318779e-01 | 0.136 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 7.318779e-01 | 0.136 | 0 | 0 |
| mRNA Editing: C to U Conversion | R-HSA-72200 | 7.318779e-01 | 0.136 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.318779e-01 | 0.136 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 7.318779e-01 | 0.136 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 7.318779e-01 | 0.136 | 0 | 0 |
| Activation of TRKA receptors | R-HSA-187015 | 7.318779e-01 | 0.136 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 7.318779e-01 | 0.136 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 7.318779e-01 | 0.136 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.318779e-01 | 0.136 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.339596e-01 | 0.134 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 7.339596e-01 | 0.134 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 7.353667e-01 | 0.133 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 7.359158e-01 | 0.133 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 7.359158e-01 | 0.133 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 7.388897e-01 | 0.131 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 7.388897e-01 | 0.131 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 7.388897e-01 | 0.131 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 7.388897e-01 | 0.131 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 7.388897e-01 | 0.131 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 7.388897e-01 | 0.131 | 0 | 0 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 7.388897e-01 | 0.131 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 7.388897e-01 | 0.131 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 7.388897e-01 | 0.131 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 7.427838e-01 | 0.129 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 7.471122e-01 | 0.127 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 7.475164e-01 | 0.126 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 7.500079e-01 | 0.125 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 7.514641e-01 | 0.124 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 7.543037e-01 | 0.122 | 1 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 7.544076e-01 | 0.122 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 7.544076e-01 | 0.122 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 7.554739e-01 | 0.122 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 7.582878e-01 | 0.120 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 7.628164e-01 | 0.118 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 7.628164e-01 | 0.118 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 7.628164e-01 | 0.118 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.628164e-01 | 0.118 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.635561e-01 | 0.117 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 7.635561e-01 | 0.117 | 0 | 0 |
| RSK activation | R-HSA-444257 | 7.649575e-01 | 0.116 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 7.649575e-01 | 0.116 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 7.649575e-01 | 0.116 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 7.649575e-01 | 0.116 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 7.649575e-01 | 0.116 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.649575e-01 | 0.116 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 7.649575e-01 | 0.116 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 7.649575e-01 | 0.116 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 7.649575e-01 | 0.116 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 7.649575e-01 | 0.116 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 7.649575e-01 | 0.116 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 7.649575e-01 | 0.116 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 7.649575e-01 | 0.116 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.649575e-01 | 0.116 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 7.649575e-01 | 0.116 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 7.649575e-01 | 0.116 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 7.649575e-01 | 0.116 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 7.704025e-01 | 0.113 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 7.704025e-01 | 0.113 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 7.704025e-01 | 0.113 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 7.708725e-01 | 0.113 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.732063e-01 | 0.112 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 7.735696e-01 | 0.112 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 7.735696e-01 | 0.112 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 7.735696e-01 | 0.112 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 7.735696e-01 | 0.112 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 7.750694e-01 | 0.111 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 7.765628e-01 | 0.110 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 7.765628e-01 | 0.110 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 7.765628e-01 | 0.110 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 7.772040e-01 | 0.109 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 7.777901e-01 | 0.109 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 7.843543e-01 | 0.105 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 7.848158e-01 | 0.105 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 7.848158e-01 | 0.105 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 7.848158e-01 | 0.105 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 7.848158e-01 | 0.105 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 7.848158e-01 | 0.105 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 7.848158e-01 | 0.105 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 7.848158e-01 | 0.105 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 7.848158e-01 | 0.105 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 7.848158e-01 | 0.105 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 7.865027e-01 | 0.104 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 7.865027e-01 | 0.104 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 7.896830e-01 | 0.103 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 7.914877e-01 | 0.102 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 7.914877e-01 | 0.102 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 7.939576e-01 | 0.100 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 7.939576e-01 | 0.100 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 7.939576e-01 | 0.100 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 7.939576e-01 | 0.100 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 7.939576e-01 | 0.100 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 7.939576e-01 | 0.100 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 7.939576e-01 | 0.100 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 7.939576e-01 | 0.100 | 0 | 0 |
| Lysosomal oligosaccharide catabolism | R-HSA-8853383 | 7.939576e-01 | 0.100 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 7.939576e-01 | 0.100 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 7.939576e-01 | 0.100 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 7.939576e-01 | 0.100 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 7.939576e-01 | 0.100 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 7.972776e-01 | 0.098 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 7.996052e-01 | 0.097 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 8.049990e-01 | 0.094 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 8.049990e-01 | 0.094 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 8.049990e-01 | 0.094 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.049990e-01 | 0.094 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 8.049990e-01 | 0.094 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 8.049990e-01 | 0.094 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.082087e-01 | 0.092 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 8.082087e-01 | 0.092 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 8.117466e-01 | 0.091 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 8.117466e-01 | 0.091 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 8.157952e-01 | 0.088 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 8.159860e-01 | 0.088 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 8.159860e-01 | 0.088 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 8.161603e-01 | 0.088 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 8.162155e-01 | 0.088 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 8.193811e-01 | 0.087 | 0 | 0 |
| TET1,2,3 and TDG demethylate DNA | R-HSA-5221030 | 8.193811e-01 | 0.087 | 0 | 0 |
| Metabolism of serotonin | R-HSA-380612 | 8.193811e-01 | 0.087 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 8.193811e-01 | 0.087 | 0 | 0 |
| Arachidonate production from DAG | R-HSA-426048 | 8.193811e-01 | 0.087 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 8.193811e-01 | 0.087 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 8.193811e-01 | 0.087 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 8.193811e-01 | 0.087 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 8.193811e-01 | 0.087 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 8.193811e-01 | 0.087 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 8.193811e-01 | 0.087 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 8.193811e-01 | 0.087 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 8.234793e-01 | 0.084 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 8.234793e-01 | 0.084 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 8.234793e-01 | 0.084 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 8.234793e-01 | 0.084 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 8.234793e-01 | 0.084 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 8.237829e-01 | 0.084 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 8.237829e-01 | 0.084 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 8.251021e-01 | 0.083 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 8.251021e-01 | 0.083 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 8.251021e-01 | 0.083 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.272744e-01 | 0.082 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 8.281179e-01 | 0.082 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 8.336937e-01 | 0.079 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 8.382630e-01 | 0.077 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.382630e-01 | 0.077 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 8.382630e-01 | 0.077 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 8.382630e-01 | 0.077 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 8.382630e-01 | 0.077 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 8.382630e-01 | 0.077 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 8.403695e-01 | 0.076 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 8.403695e-01 | 0.076 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 8.413351e-01 | 0.075 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 8.416689e-01 | 0.075 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 8.416689e-01 | 0.075 | 0 | 0 |
| FGFR2b ligand binding and activation | R-HSA-190377 | 8.416689e-01 | 0.075 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 8.416689e-01 | 0.075 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 8.416689e-01 | 0.075 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 8.416689e-01 | 0.075 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 8.416689e-01 | 0.075 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 8.416689e-01 | 0.075 | 0 | 0 |
| Biosynthesis of DPAn-3-derived maresins | R-HSA-9026290 | 8.416689e-01 | 0.075 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 8.416689e-01 | 0.075 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 8.416689e-01 | 0.075 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 8.416689e-01 | 0.075 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 8.416689e-01 | 0.075 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 8.440528e-01 | 0.074 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 8.449519e-01 | 0.073 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 8.452517e-01 | 0.073 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 8.480460e-01 | 0.072 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 8.517032e-01 | 0.070 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 8.557806e-01 | 0.068 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 8.557806e-01 | 0.068 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 8.557806e-01 | 0.068 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 8.557806e-01 | 0.068 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 8.557806e-01 | 0.068 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 8.557806e-01 | 0.068 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 8.557806e-01 | 0.068 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 8.557806e-01 | 0.068 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 8.561402e-01 | 0.067 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 8.568629e-01 | 0.067 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 8.612076e-01 | 0.065 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 8.612076e-01 | 0.065 | 0 | 0 |
| Presynaptic nicotinic acetylcholine receptors | R-HSA-622323 | 8.612076e-01 | 0.065 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 8.612076e-01 | 0.065 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 8.612076e-01 | 0.065 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 8.612076e-01 | 0.065 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.612076e-01 | 0.065 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 8.612076e-01 | 0.065 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 8.612076e-01 | 0.065 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 8.612076e-01 | 0.065 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 8.612076e-01 | 0.065 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 8.612076e-01 | 0.065 | 0 | 0 |
| Uptake of dietary cobalamins into enterocytes | R-HSA-9758881 | 8.612076e-01 | 0.065 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 8.618931e-01 | 0.065 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 8.629417e-01 | 0.064 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.641582e-01 | 0.063 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 8.641582e-01 | 0.063 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 8.649143e-01 | 0.063 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 8.649143e-01 | 0.063 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 8.684378e-01 | 0.061 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 8.691150e-01 | 0.061 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 8.698203e-01 | 0.061 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 8.698203e-01 | 0.061 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 8.698203e-01 | 0.061 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 8.698203e-01 | 0.061 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.698203e-01 | 0.061 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 8.752467e-01 | 0.058 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 8.758761e-01 | 0.058 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 8.766001e-01 | 0.057 | 1 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.777359e-01 | 0.057 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 8.783361e-01 | 0.056 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 8.783361e-01 | 0.056 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 8.783361e-01 | 0.056 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.783361e-01 | 0.056 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 8.783361e-01 | 0.056 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 8.783361e-01 | 0.056 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 8.783361e-01 | 0.056 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 8.783361e-01 | 0.056 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 8.783361e-01 | 0.056 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 8.783361e-01 | 0.056 | 0 | 0 |
| Biosynthesis of DPAn-3-derived protectins and resolvins | R-HSA-9026286 | 8.783361e-01 | 0.056 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 8.783361e-01 | 0.056 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.783361e-01 | 0.056 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 8.816426e-01 | 0.055 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 8.816426e-01 | 0.055 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 8.825923e-01 | 0.054 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 8.825923e-01 | 0.054 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 8.825923e-01 | 0.054 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 8.825923e-01 | 0.054 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 8.825923e-01 | 0.054 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 8.825923e-01 | 0.054 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 8.848881e-01 | 0.053 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 8.848881e-01 | 0.053 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 8.848881e-01 | 0.053 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 8.848881e-01 | 0.053 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 8.848881e-01 | 0.053 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 8.862341e-01 | 0.052 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 8.892879e-01 | 0.051 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.895793e-01 | 0.051 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 8.895793e-01 | 0.051 | 0 | 0 |
| FGFR2c ligand binding and activation | R-HSA-190375 | 8.933516e-01 | 0.049 | 0 | 0 |
| Postsynaptic nicotinic acetylcholine receptors | R-HSA-622327 | 8.933516e-01 | 0.049 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 8.933516e-01 | 0.049 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.933516e-01 | 0.049 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 8.933516e-01 | 0.049 | 0 | 0 |
| Acetylcholine binding and downstream events | R-HSA-181431 | 8.933516e-01 | 0.049 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.933516e-01 | 0.049 | 0 | 0 |
| Mtb iron assimilation by chelation | R-HSA-1222449 | 8.933516e-01 | 0.049 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 8.933516e-01 | 0.049 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 8.933516e-01 | 0.049 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 8.933516e-01 | 0.049 | 0 | 0 |
| rRNA modification in the mitochondrion | R-HSA-6793080 | 8.933516e-01 | 0.049 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 8.933516e-01 | 0.049 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 8.933516e-01 | 0.049 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 8.933516e-01 | 0.049 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.933516e-01 | 0.049 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 8.941957e-01 | 0.049 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 8.941957e-01 | 0.049 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 8.941957e-01 | 0.049 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 8.941957e-01 | 0.049 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 8.941957e-01 | 0.049 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 8.941957e-01 | 0.049 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.946597e-01 | 0.048 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 8.946597e-01 | 0.048 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.946597e-01 | 0.048 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 8.946597e-01 | 0.048 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.961569e-01 | 0.048 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 8.970588e-01 | 0.047 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 8.970588e-01 | 0.047 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 9.003253e-01 | 0.046 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 9.003859e-01 | 0.046 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 9.003859e-01 | 0.046 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 9.022360e-01 | 0.045 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.047243e-01 | 0.043 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 9.047243e-01 | 0.043 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.047243e-01 | 0.043 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 9.047243e-01 | 0.043 | 0 | 0 |
| Synthesis of dolichyl-phosphate | R-HSA-446199 | 9.047243e-01 | 0.043 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.047243e-01 | 0.043 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 9.051438e-01 | 0.043 | 1 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 9.052115e-01 | 0.043 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.052115e-01 | 0.043 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.052115e-01 | 0.043 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.052115e-01 | 0.043 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.052115e-01 | 0.043 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 9.065148e-01 | 0.043 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 9.065148e-01 | 0.043 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 9.065148e-01 | 0.043 | 0 | 0 |
| The activation of arylsulfatases | R-HSA-1663150 | 9.065148e-01 | 0.043 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 9.065148e-01 | 0.043 | 0 | 0 |
| Biosynthesis of E-series 18(R)-resolvins | R-HSA-9023661 | 9.065148e-01 | 0.043 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 9.065148e-01 | 0.043 | 0 | 0 |
| Glycerophospholipid catabolism | R-HSA-6814848 | 9.065148e-01 | 0.043 | 0 | 0 |
| Ciprofloxacin ADME | R-HSA-9793528 | 9.065148e-01 | 0.043 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 9.065148e-01 | 0.043 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 9.065148e-01 | 0.043 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 9.066424e-01 | 0.043 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 9.066424e-01 | 0.043 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 9.066424e-01 | 0.043 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 9.066424e-01 | 0.043 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.089469e-01 | 0.041 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.100108e-01 | 0.041 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 9.107227e-01 | 0.041 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 9.135454e-01 | 0.039 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.135454e-01 | 0.039 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.135454e-01 | 0.039 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.135454e-01 | 0.039 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 9.135454e-01 | 0.039 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 9.135454e-01 | 0.039 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.135454e-01 | 0.039 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.135454e-01 | 0.039 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.142665e-01 | 0.039 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.142665e-01 | 0.039 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.142665e-01 | 0.039 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 9.156478e-01 | 0.038 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 9.162347e-01 | 0.038 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 9.162347e-01 | 0.038 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 9.169448e-01 | 0.038 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 9.169448e-01 | 0.038 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.172306e-01 | 0.038 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 9.172306e-01 | 0.038 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 9.180539e-01 | 0.037 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 9.180539e-01 | 0.037 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 9.180539e-01 | 0.037 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 9.180539e-01 | 0.037 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 9.180539e-01 | 0.037 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 9.180539e-01 | 0.037 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 9.180539e-01 | 0.037 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 9.180539e-01 | 0.037 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 9.180539e-01 | 0.037 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 9.186634e-01 | 0.037 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 9.186634e-01 | 0.037 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.192910e-01 | 0.037 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.192910e-01 | 0.037 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.192910e-01 | 0.037 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 9.195231e-01 | 0.036 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.212070e-01 | 0.036 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.212070e-01 | 0.036 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.212070e-01 | 0.036 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 9.225076e-01 | 0.035 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 9.229055e-01 | 0.035 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 9.229055e-01 | 0.035 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.229055e-01 | 0.035 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 9.229055e-01 | 0.035 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.229055e-01 | 0.035 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.229055e-01 | 0.035 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 9.234591e-01 | 0.035 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.236534e-01 | 0.034 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.239276e-01 | 0.034 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 9.239276e-01 | 0.034 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 9.239276e-01 | 0.034 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.239276e-01 | 0.034 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.239276e-01 | 0.034 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.239276e-01 | 0.034 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 9.251946e-01 | 0.034 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 9.251946e-01 | 0.034 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.260246e-01 | 0.033 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 9.281693e-01 | 0.032 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 9.281693e-01 | 0.032 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 9.281693e-01 | 0.032 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 9.281693e-01 | 0.032 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 9.281693e-01 | 0.032 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 9.281693e-01 | 0.032 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 9.281693e-01 | 0.032 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 9.281693e-01 | 0.032 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 9.281693e-01 | 0.032 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 9.281693e-01 | 0.032 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.282425e-01 | 0.032 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.282425e-01 | 0.032 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.282425e-01 | 0.032 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.283401e-01 | 0.032 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.299613e-01 | 0.032 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 9.301332e-01 | 0.031 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.307187e-01 | 0.031 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.307187e-01 | 0.031 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.307187e-01 | 0.031 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.307187e-01 | 0.031 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.307187e-01 | 0.031 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.307187e-01 | 0.031 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 9.327761e-01 | 0.030 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 9.338162e-01 | 0.030 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 9.340041e-01 | 0.030 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 9.346964e-01 | 0.029 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.358775e-01 | 0.029 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 9.370366e-01 | 0.028 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 9.370366e-01 | 0.028 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.370366e-01 | 0.028 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.370366e-01 | 0.028 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 9.370366e-01 | 0.028 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.370366e-01 | 0.028 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 9.370366e-01 | 0.028 | 0 | 0 |
| Vitamin B6 activation to pyridoxal phosphate | R-HSA-964975 | 9.370366e-01 | 0.028 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 9.370366e-01 | 0.028 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 9.370366e-01 | 0.028 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 9.370366e-01 | 0.028 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 9.370366e-01 | 0.028 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 9.370366e-01 | 0.028 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 9.370366e-01 | 0.028 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 9.377784e-01 | 0.028 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.377784e-01 | 0.028 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 9.406107e-01 | 0.027 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 9.406107e-01 | 0.027 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 9.409374e-01 | 0.026 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 9.411896e-01 | 0.026 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 9.426894e-01 | 0.026 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.441514e-01 | 0.025 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 9.441514e-01 | 0.025 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 9.448097e-01 | 0.025 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.448097e-01 | 0.025 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 9.448097e-01 | 0.025 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 9.448097e-01 | 0.025 | 0 | 0 |
| Biosynthesis of aspirin-triggered D-series resolvins | R-HSA-9020265 | 9.448097e-01 | 0.025 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 9.448097e-01 | 0.025 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 9.448097e-01 | 0.025 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 9.448097e-01 | 0.025 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 9.448097e-01 | 0.025 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 9.448097e-01 | 0.025 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 9.460251e-01 | 0.024 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.461600e-01 | 0.024 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 9.468876e-01 | 0.024 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 9.498997e-01 | 0.022 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.498997e-01 | 0.022 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.506274e-01 | 0.022 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 9.509774e-01 | 0.022 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 9.516236e-01 | 0.022 | 0 | 0 |
| Activated point mutants of FGFR2 | R-HSA-2033519 | 9.516236e-01 | 0.022 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 9.516236e-01 | 0.022 | 0 | 0 |
| Biosynthesis of Lipoxins (LX) | R-HSA-2142700 | 9.516236e-01 | 0.022 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.516236e-01 | 0.022 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 9.516236e-01 | 0.022 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.516236e-01 | 0.022 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 9.521003e-01 | 0.021 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.521003e-01 | 0.021 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.521380e-01 | 0.021 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.525797e-01 | 0.021 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.525797e-01 | 0.021 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 9.526256e-01 | 0.021 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 9.548051e-01 | 0.020 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 9.550804e-01 | 0.020 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 9.550804e-01 | 0.020 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 9.550804e-01 | 0.020 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.550804e-01 | 0.020 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.550804e-01 | 0.020 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 9.550804e-01 | 0.020 | 0 | 0 |
| Synthesis of glycosylphosphatidylinositol (GPI) | R-HSA-162710 | 9.550804e-01 | 0.020 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.550804e-01 | 0.020 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.555029e-01 | 0.020 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 9.555935e-01 | 0.020 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.572242e-01 | 0.019 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.575965e-01 | 0.019 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 9.575965e-01 | 0.019 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 9.575965e-01 | 0.019 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.575965e-01 | 0.019 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.575965e-01 | 0.019 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 9.586546e-01 | 0.018 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 9.586546e-01 | 0.018 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 9.596348e-01 | 0.018 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.596348e-01 | 0.018 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.596348e-01 | 0.018 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 9.616909e-01 | 0.017 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 9.618599e-01 | 0.017 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 9.618599e-01 | 0.017 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.621987e-01 | 0.017 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 9.628323e-01 | 0.016 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.628323e-01 | 0.016 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.628323e-01 | 0.016 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 9.628323e-01 | 0.016 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 9.628323e-01 | 0.016 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.628323e-01 | 0.016 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.634043e-01 | 0.016 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 9.639445e-01 | 0.016 | 0 | 0 |
| Defective B3GALTL causes PpS | R-HSA-5083635 | 9.639445e-01 | 0.016 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 9.639445e-01 | 0.016 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 9.640075e-01 | 0.016 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.654590e-01 | 0.015 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 9.654590e-01 | 0.015 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 9.658800e-01 | 0.015 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 9.658800e-01 | 0.015 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.667577e-01 | 0.015 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.668404e-01 | 0.015 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 9.668404e-01 | 0.015 | 0 | 0 |
| FGFR2 ligand binding and activation | R-HSA-190241 | 9.674219e-01 | 0.014 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.674219e-01 | 0.014 | 0 | 0 |
| Biosynthesis of E-series 18(S)-resolvins | R-HSA-9018896 | 9.674219e-01 | 0.014 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.674219e-01 | 0.014 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.674219e-01 | 0.014 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 9.674219e-01 | 0.014 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.674219e-01 | 0.014 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 9.674219e-01 | 0.014 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 9.674219e-01 | 0.014 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 9.674219e-01 | 0.014 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 9.677203e-01 | 0.014 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.677203e-01 | 0.014 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.677203e-01 | 0.014 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.684560e-01 | 0.014 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.684560e-01 | 0.014 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 9.685658e-01 | 0.014 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 9.685658e-01 | 0.014 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.693140e-01 | 0.014 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.699703e-01 | 0.013 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 9.699703e-01 | 0.013 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.711137e-01 | 0.013 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.711137e-01 | 0.013 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 9.711137e-01 | 0.013 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.712088e-01 | 0.013 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.712088e-01 | 0.013 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 9.714450e-01 | 0.013 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 9.714450e-01 | 0.013 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.714450e-01 | 0.013 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.714450e-01 | 0.013 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.716886e-01 | 0.012 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 9.721324e-01 | 0.012 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 9.724274e-01 | 0.012 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 9.738927e-01 | 0.011 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.739737e-01 | 0.011 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 9.741182e-01 | 0.011 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.741615e-01 | 0.011 | 0 | 0 |
| Biosynthesis of D-series resolvins | R-HSA-9018676 | 9.749714e-01 | 0.011 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.749714e-01 | 0.011 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 9.749714e-01 | 0.011 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 9.749920e-01 | 0.011 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 9.752220e-01 | 0.011 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.752220e-01 | 0.011 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.754102e-01 | 0.011 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 9.760529e-01 | 0.011 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 9.760529e-01 | 0.011 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.771025e-01 | 0.010 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.776361e-01 | 0.010 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 9.777653e-01 | 0.010 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.777653e-01 | 0.010 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.780626e-01 | 0.010 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.780626e-01 | 0.010 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.780626e-01 | 0.010 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 9.780626e-01 | 0.010 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.780626e-01 | 0.010 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.780626e-01 | 0.010 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.781771e-01 | 0.010 | 0 | 0 |
| O-glycosylation of TSR domain-containing proteins | R-HSA-5173214 | 9.793517e-01 | 0.009 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.793517e-01 | 0.009 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 9.793517e-01 | 0.009 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 9.793517e-01 | 0.009 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.793517e-01 | 0.009 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 9.794042e-01 | 0.009 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.799046e-01 | 0.009 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 9.799046e-01 | 0.009 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.801125e-01 | 0.009 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.803235e-01 | 0.009 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 9.807721e-01 | 0.008 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.807721e-01 | 0.008 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 9.807721e-01 | 0.008 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.807721e-01 | 0.008 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.807721e-01 | 0.008 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.815524e-01 | 0.008 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.818534e-01 | 0.008 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.831471e-01 | 0.007 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.831471e-01 | 0.007 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.831471e-01 | 0.007 | 0 | 0 |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | R-HSA-9027604 | 9.831471e-01 | 0.007 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.831471e-01 | 0.007 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.831471e-01 | 0.007 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.831471e-01 | 0.007 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.832022e-01 | 0.007 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.835246e-01 | 0.007 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.835246e-01 | 0.007 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.835246e-01 | 0.007 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.836083e-01 | 0.007 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.836083e-01 | 0.007 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.836083e-01 | 0.007 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.836083e-01 | 0.007 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.842713e-01 | 0.007 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.852289e-01 | 0.006 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.852289e-01 | 0.006 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 9.852913e-01 | 0.006 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 9.852913e-01 | 0.006 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 9.852913e-01 | 0.006 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 9.852913e-01 | 0.006 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.853964e-01 | 0.006 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 9.856130e-01 | 0.006 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.863385e-01 | 0.006 | 1 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 9.865842e-01 | 0.006 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.868730e-01 | 0.006 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.868730e-01 | 0.006 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 9.868730e-01 | 0.006 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 9.870536e-01 | 0.006 | 0 | 0 |
| Cobalamin (Cbl) metabolism | R-HSA-9759218 | 9.870536e-01 | 0.006 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.870536e-01 | 0.006 | 0 | 0 |
| Biosynthesis of DPAn-3 SPMs | R-HSA-9025094 | 9.870536e-01 | 0.006 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.870536e-01 | 0.006 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.879789e-01 | 0.005 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.879789e-01 | 0.005 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 9.884041e-01 | 0.005 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.886530e-01 | 0.005 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.886530e-01 | 0.005 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.887605e-01 | 0.005 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.889052e-01 | 0.005 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.895547e-01 | 0.005 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.897951e-01 | 0.004 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.898411e-01 | 0.004 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.900549e-01 | 0.004 | 0 | 0 |
| Biosynthesis of EPA-derived SPMs | R-HSA-9018679 | 9.900549e-01 | 0.004 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.900549e-01 | 0.004 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 9.906869e-01 | 0.004 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.906869e-01 | 0.004 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.908484e-01 | 0.004 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.912411e-01 | 0.004 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 9.912837e-01 | 0.004 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.912837e-01 | 0.004 | 0 | 0 |
| Mucopolysaccharidoses | R-HSA-2206281 | 9.912837e-01 | 0.004 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.915978e-01 | 0.004 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.923607e-01 | 0.003 | 0 | 0 |
| Biosynthesis of DPA-derived SPMs | R-HSA-9018683 | 9.923607e-01 | 0.003 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.923805e-01 | 0.003 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.923922e-01 | 0.003 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.926030e-01 | 0.003 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.928639e-01 | 0.003 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.928639e-01 | 0.003 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.932963e-01 | 0.003 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.933047e-01 | 0.003 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.933047e-01 | 0.003 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.936883e-01 | 0.003 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 9.939051e-01 | 0.003 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 9.941315e-01 | 0.003 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.941315e-01 | 0.003 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.941320e-01 | 0.003 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.941320e-01 | 0.003 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 9.942253e-01 | 0.003 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 9.942253e-01 | 0.003 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.943307e-01 | 0.002 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 9.948078e-01 | 0.002 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.948078e-01 | 0.002 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.948572e-01 | 0.002 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 9.948572e-01 | 0.002 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.948665e-01 | 0.002 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 9.952241e-01 | 0.002 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.953491e-01 | 0.002 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 9.954461e-01 | 0.002 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.954928e-01 | 0.002 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 9.954928e-01 | 0.002 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.954928e-01 | 0.002 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.954928e-01 | 0.002 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.954928e-01 | 0.002 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 9.954928e-01 | 0.002 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 9.957981e-01 | 0.002 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 9.958555e-01 | 0.002 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.959598e-01 | 0.002 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.960499e-01 | 0.002 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.960499e-01 | 0.002 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.960499e-01 | 0.002 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 9.960499e-01 | 0.002 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.961970e-01 | 0.002 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.964199e-01 | 0.002 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.965382e-01 | 0.002 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.965382e-01 | 0.002 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.966178e-01 | 0.001 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.969638e-01 | 0.001 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 9.969661e-01 | 0.001 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.969661e-01 | 0.001 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.969661e-01 | 0.001 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.970873e-01 | 0.001 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.972001e-01 | 0.001 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.973034e-01 | 0.001 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.973034e-01 | 0.001 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.973411e-01 | 0.001 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.973411e-01 | 0.001 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.976698e-01 | 0.001 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.976698e-01 | 0.001 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.976698e-01 | 0.001 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.977085e-01 | 0.001 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.979579e-01 | 0.001 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.979579e-01 | 0.001 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.979643e-01 | 0.001 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.980339e-01 | 0.001 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.982104e-01 | 0.001 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.982104e-01 | 0.001 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.984317e-01 | 0.001 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.984317e-01 | 0.001 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.984403e-01 | 0.001 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 9.984805e-01 | 0.001 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.985658e-01 | 0.001 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.986256e-01 | 0.001 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.986298e-01 | 0.001 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.987671e-01 | 0.001 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.987956e-01 | 0.001 | 0 | 0 |
| Translation | R-HSA-72766 | 9.988283e-01 | 0.001 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.988483e-01 | 0.001 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.988483e-01 | 0.001 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.988692e-01 | 0.000 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.988692e-01 | 0.000 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.988868e-01 | 0.000 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 9.989305e-01 | 0.000 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.989445e-01 | 0.000 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.989445e-01 | 0.000 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.989445e-01 | 0.000 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.989445e-01 | 0.000 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 9.989706e-01 | 0.000 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 9.989762e-01 | 0.000 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.990751e-01 | 0.000 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.990751e-01 | 0.000 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.990751e-01 | 0.000 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.990987e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.991091e-01 | 0.000 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 9.991864e-01 | 0.000 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.991895e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.993348e-01 | 0.000 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.993368e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.993776e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.993963e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.994481e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.994481e-01 | 0.000 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.994546e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.995106e-01 | 0.000 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.995221e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.995683e-01 | 0.000 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.995708e-01 | 0.000 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 9.995960e-01 | 0.000 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.996153e-01 | 0.000 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.996512e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.996512e-01 | 0.000 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.996590e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.996590e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.996866e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.996977e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.997321e-01 | 0.000 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.997531e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.997531e-01 | 0.000 | 0 | 0 |
| Digestion | R-HSA-8935690 | 9.997836e-01 | 0.000 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.997888e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.997888e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.997961e-01 | 0.000 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.998233e-01 | 0.000 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.998344e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.998357e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.998531e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.998544e-01 | 0.000 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.998693e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.998706e-01 | 0.000 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.998725e-01 | 0.000 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.998725e-01 | 0.000 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.998725e-01 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.998838e-01 | 0.000 | 1 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.998882e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999046e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.999075e-01 | 0.000 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.999142e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999145e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999154e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999234e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.999248e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.999248e-01 | 0.000 | 0 | 0 |
| Latent infection - Other responses of Mtb to phagocytosis | R-HSA-1222499 | 9.999341e-01 | 0.000 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.999506e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999513e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999619e-01 | 0.000 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.999619e-01 | 0.000 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.999656e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999660e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999818e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.999824e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999882e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999882e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999921e-01 | 0.000 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.999938e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999947e-01 | 0.000 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.999947e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999947e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999974e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999976e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999979e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999988e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.999990e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999992e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999997e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999997e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999997e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999998e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999999e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999999e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999999e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.999999e-01 | 0.000 | 0 | 0 |
| Initial triggering of complement | R-HSA-166663 | 9.999999e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.000000e+00 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| M Phase | R-HSA-68886 | 1.110223e-16 | 15.955 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.110223e-16 | 15.955 | 1 | 0 |
| Nervous system development | R-HSA-9675108 | 1.110223e-16 | 15.955 | 1 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.654232e-14 | 13.781 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.253753e-14 | 13.647 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 2.642331e-14 | 13.578 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 5.662137e-14 | 13.247 | 1 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.271983e-12 | 11.896 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 3.138600e-12 | 11.503 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 4.706568e-12 | 11.327 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 4.676703e-12 | 11.330 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 4.676703e-12 | 11.330 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 4.575562e-12 | 11.340 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 5.262679e-12 | 11.279 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 6.560308e-12 | 11.183 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 7.015499e-12 | 11.154 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 7.804424e-12 | 11.108 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.139588e-11 | 10.943 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.171185e-11 | 10.931 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 3.681899e-11 | 10.434 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 5.518486e-11 | 10.258 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 7.918943e-11 | 10.101 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.564978e-10 | 9.805 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.564978e-10 | 9.805 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.781889e-10 | 9.749 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.988399e-10 | 9.701 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.071837e-10 | 9.684 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 2.619776e-10 | 9.582 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 3.115259e-10 | 9.507 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 3.678089e-10 | 9.434 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 7.786893e-10 | 9.109 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 7.790122e-10 | 9.108 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.034862e-09 | 8.985 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 1.260416e-09 | 8.899 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.619915e-09 | 8.791 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 1.594826e-09 | 8.797 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.934837e-09 | 8.713 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 2.067939e-09 | 8.684 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 2.722310e-09 | 8.565 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 2.822399e-09 | 8.549 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.819135e-09 | 8.550 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 4.297890e-09 | 8.367 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 4.417613e-09 | 8.355 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 4.680820e-09 | 8.330 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 4.680820e-09 | 8.330 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 6.010542e-09 | 8.221 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 6.299722e-09 | 8.201 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 7.713386e-09 | 8.113 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 7.936078e-09 | 8.100 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 1.146318e-08 | 7.941 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.501555e-08 | 7.823 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.745274e-08 | 7.758 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.708100e-08 | 7.767 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.848444e-08 | 7.733 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.847516e-08 | 7.733 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 1.887421e-08 | 7.724 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.887153e-08 | 7.724 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.913704e-08 | 7.718 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 2.081873e-08 | 7.682 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 2.287595e-08 | 7.641 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 2.455574e-08 | 7.610 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 2.683740e-08 | 7.571 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 3.517138e-08 | 7.454 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 4.411696e-08 | 7.355 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 4.260326e-08 | 7.371 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 4.708867e-08 | 7.327 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 5.141433e-08 | 7.289 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 5.136485e-08 | 7.289 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 5.348767e-08 | 7.272 | 1 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 6.279688e-08 | 7.202 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 7.809099e-08 | 7.107 | 0 | 0 |
| Kinesins | R-HSA-983189 | 8.005224e-08 | 7.097 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 9.284051e-08 | 7.032 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 9.928607e-08 | 7.003 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.007107e-07 | 6.997 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 1.163648e-07 | 6.934 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 1.280225e-07 | 6.893 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.459889e-07 | 6.836 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.567161e-07 | 6.805 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.606726e-07 | 6.794 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.648636e-07 | 6.783 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.685153e-07 | 6.773 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 1.731890e-07 | 6.761 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 1.894032e-07 | 6.723 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.941217e-07 | 6.712 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 2.120065e-07 | 6.674 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 2.283046e-07 | 6.641 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 2.315092e-07 | 6.635 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 2.895829e-07 | 6.538 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 2.895829e-07 | 6.538 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 3.042640e-07 | 6.517 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 3.747030e-07 | 6.426 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 4.020058e-07 | 6.396 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 4.750119e-07 | 6.323 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 4.759730e-07 | 6.322 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 4.906599e-07 | 6.309 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 5.311457e-07 | 6.275 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 5.401679e-07 | 6.267 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 6.366771e-07 | 6.196 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 8.043245e-07 | 6.095 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 8.099354e-07 | 6.092 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 9.152206e-07 | 6.038 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.009166e-06 | 5.996 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 1.032004e-06 | 5.986 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 1.032004e-06 | 5.986 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.059914e-06 | 5.975 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 1.095848e-06 | 5.960 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 1.159829e-06 | 5.936 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.188608e-06 | 5.925 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 1.215018e-06 | 5.915 | 1 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.259561e-06 | 5.900 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.479718e-06 | 5.830 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 1.803679e-06 | 5.744 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 1.771814e-06 | 5.752 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 1.834794e-06 | 5.736 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.834794e-06 | 5.736 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 1.902359e-06 | 5.721 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 2.232795e-06 | 5.651 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 2.538284e-06 | 5.595 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 2.634652e-06 | 5.579 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 2.865577e-06 | 5.543 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 3.057014e-06 | 5.515 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 3.110402e-06 | 5.507 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 3.275205e-06 | 5.485 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 3.546449e-06 | 5.450 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 3.642125e-06 | 5.439 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 3.715530e-06 | 5.430 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 3.723748e-06 | 5.429 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 3.809697e-06 | 5.419 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 4.159014e-06 | 5.381 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 4.552570e-06 | 5.342 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 4.750031e-06 | 5.323 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 5.025625e-06 | 5.299 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 5.025625e-06 | 5.299 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 5.088192e-06 | 5.293 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 5.088192e-06 | 5.293 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 5.088192e-06 | 5.293 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 5.088192e-06 | 5.293 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 5.088192e-06 | 5.293 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 5.090493e-06 | 5.293 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 5.969087e-06 | 5.224 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 6.336364e-06 | 5.198 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 6.351054e-06 | 5.197 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 7.479198e-06 | 5.126 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 9.681537e-06 | 5.014 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 9.681537e-06 | 5.014 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.014641e-05 | 4.994 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.063529e-05 | 4.973 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.090425e-05 | 4.962 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.122785e-05 | 4.950 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.306531e-05 | 4.884 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 1.321307e-05 | 4.879 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.439332e-05 | 4.842 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.585143e-05 | 4.800 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 1.605381e-05 | 4.794 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.696949e-05 | 4.770 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.710627e-05 | 4.767 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.781604e-05 | 4.749 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.866674e-05 | 4.729 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 1.893465e-05 | 4.723 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.949261e-05 | 4.710 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 2.147797e-05 | 4.668 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 2.428803e-05 | 4.615 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 2.283453e-05 | 4.641 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 2.479818e-05 | 4.606 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 2.561706e-05 | 4.591 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.778387e-05 | 4.556 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 2.844874e-05 | 4.546 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 3.045759e-05 | 4.516 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 3.123938e-05 | 4.505 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 3.398627e-05 | 4.469 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 3.398627e-05 | 4.469 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 3.604665e-05 | 4.443 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 3.632495e-05 | 4.440 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 3.858414e-05 | 4.414 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.921710e-05 | 4.407 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 3.988247e-05 | 4.399 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 4.109417e-05 | 4.386 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 5.033937e-05 | 4.298 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 5.404213e-05 | 4.267 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 5.558784e-05 | 4.255 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 5.684637e-05 | 4.245 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 6.065747e-05 | 4.217 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 6.078538e-05 | 4.216 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 6.101207e-05 | 4.215 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 6.375567e-05 | 4.195 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 6.531895e-05 | 4.185 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 6.531895e-05 | 4.185 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 6.531895e-05 | 4.185 | 1 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 6.817433e-05 | 4.166 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 6.817433e-05 | 4.166 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 6.849431e-05 | 4.164 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 7.086722e-05 | 4.150 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 8.100930e-05 | 4.091 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 9.238295e-05 | 4.034 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 8.397974e-05 | 4.076 | 0 | 0 |
| Depurination | R-HSA-73927 | 8.703439e-05 | 4.060 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.164676e-04 | 3.934 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.269131e-04 | 3.896 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.445883e-04 | 3.840 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 1.504869e-04 | 3.823 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.552547e-04 | 3.809 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 1.637419e-04 | 3.786 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.647247e-04 | 3.783 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.647247e-04 | 3.783 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 1.842939e-04 | 3.734 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.842939e-04 | 3.734 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 1.842939e-04 | 3.734 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 1.894582e-04 | 3.722 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 1.894582e-04 | 3.722 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.945495e-04 | 3.711 | 1 | 0 |
| Protein folding | R-HSA-391251 | 1.970011e-04 | 3.706 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.970011e-04 | 3.706 | 1 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 2.017430e-04 | 3.695 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 2.154570e-04 | 3.667 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 2.133060e-04 | 3.671 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.058587e-04 | 3.686 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.289925e-04 | 3.640 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 2.316860e-04 | 3.635 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 2.503573e-04 | 3.601 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.572051e-04 | 3.590 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 2.572051e-04 | 3.590 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 2.659234e-04 | 3.575 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 2.659234e-04 | 3.575 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 2.750722e-04 | 3.561 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 2.775883e-04 | 3.557 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 2.949542e-04 | 3.530 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 3.342377e-04 | 3.476 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 3.342377e-04 | 3.476 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 3.387043e-04 | 3.470 | 1 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 3.559746e-04 | 3.449 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 3.654820e-04 | 3.437 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 3.794177e-04 | 3.421 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 3.826012e-04 | 3.417 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 4.201648e-04 | 3.377 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 4.321621e-04 | 3.364 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 4.321621e-04 | 3.364 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 4.455759e-04 | 3.351 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 4.622934e-04 | 3.335 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 4.698393e-04 | 3.328 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 4.982829e-04 | 3.303 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 5.095004e-04 | 3.293 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 5.095004e-04 | 3.293 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 5.780192e-04 | 3.238 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 5.814065e-04 | 3.236 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 6.256683e-04 | 3.204 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 6.405632e-04 | 3.193 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 7.267301e-04 | 3.139 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 6.696331e-04 | 3.174 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 7.199411e-04 | 3.143 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 7.652820e-04 | 3.116 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 7.267301e-04 | 3.139 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 8.105153e-04 | 3.091 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 8.302358e-04 | 3.081 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 8.380763e-04 | 3.077 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 8.451548e-04 | 3.073 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 8.470100e-04 | 3.072 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 8.478859e-04 | 3.072 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 8.478859e-04 | 3.072 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 8.822140e-04 | 3.054 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 8.822140e-04 | 3.054 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 8.822140e-04 | 3.054 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 9.003963e-04 | 3.046 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 9.661078e-04 | 3.015 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 9.973506e-04 | 3.001 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 1.019818e-03 | 2.991 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 1.019818e-03 | 2.991 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.019818e-03 | 2.991 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 1.055460e-03 | 2.977 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.055460e-03 | 2.977 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 1.055460e-03 | 2.977 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.062607e-03 | 2.974 | 1 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.118614e-03 | 2.951 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.161858e-03 | 2.935 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.180119e-03 | 2.928 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.185459e-03 | 2.926 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 1.243790e-03 | 2.905 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.258678e-03 | 2.900 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 1.287042e-03 | 2.890 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 1.287042e-03 | 2.890 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.287042e-03 | 2.890 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.401929e-03 | 2.853 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.443390e-03 | 2.841 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 1.451010e-03 | 2.838 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 1.469284e-03 | 2.833 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 1.513863e-03 | 2.820 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.521412e-03 | 2.818 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.578598e-03 | 2.802 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.628194e-03 | 2.788 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 1.628194e-03 | 2.788 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.687746e-03 | 2.773 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.782919e-03 | 2.749 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 2.041411e-03 | 2.690 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.720435e-03 | 2.764 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.941734e-03 | 2.712 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 1.880234e-03 | 2.726 | 0 | 0 |
| Translation | R-HSA-72766 | 1.709989e-03 | 2.767 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.190709e-03 | 2.659 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 2.215503e-03 | 2.655 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 2.288187e-03 | 2.641 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 2.315035e-03 | 2.635 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 2.392496e-03 | 2.621 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 2.426417e-03 | 2.615 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 2.426417e-03 | 2.615 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 2.426417e-03 | 2.615 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.426417e-03 | 2.615 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 2.523825e-03 | 2.598 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 2.657395e-03 | 2.576 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 2.694090e-03 | 2.570 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 2.761535e-03 | 2.559 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 2.784385e-03 | 2.555 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 2.806315e-03 | 2.552 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.819296e-03 | 2.550 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 2.994026e-03 | 2.524 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 3.041386e-03 | 2.517 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 3.156863e-03 | 2.501 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 3.161160e-03 | 2.500 | 1 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 3.206227e-03 | 2.494 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 3.206227e-03 | 2.494 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 3.255244e-03 | 2.487 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 3.341820e-03 | 2.476 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 3.450925e-03 | 2.462 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 3.477816e-03 | 2.459 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 3.523548e-03 | 2.453 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 3.642273e-03 | 2.439 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 3.717609e-03 | 2.430 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 3.717609e-03 | 2.430 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 3.776557e-03 | 2.423 | 1 | 1 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 3.776557e-03 | 2.423 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.776557e-03 | 2.423 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 3.776557e-03 | 2.423 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.781424e-03 | 2.422 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 3.837404e-03 | 2.416 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 3.849769e-03 | 2.415 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 3.878511e-03 | 2.411 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 3.935481e-03 | 2.405 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 3.935481e-03 | 2.405 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 4.231576e-03 | 2.373 | 1 | 1 |
| Activation of BH3-only proteins | R-HSA-114452 | 4.507710e-03 | 2.346 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 4.528971e-03 | 2.344 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 4.687175e-03 | 2.329 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 4.687175e-03 | 2.329 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 4.687175e-03 | 2.329 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 5.837349e-03 | 2.234 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 5.837349e-03 | 2.234 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 4.835070e-03 | 2.316 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 5.879798e-03 | 2.231 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 5.879798e-03 | 2.231 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 5.879798e-03 | 2.231 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 5.804759e-03 | 2.236 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 5.609513e-03 | 2.251 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 5.401678e-03 | 2.267 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 5.433241e-03 | 2.265 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.204718e-03 | 2.284 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 4.982837e-03 | 2.303 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 5.433241e-03 | 2.265 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 4.868070e-03 | 2.313 | 1 | 0 |
| CaM pathway | R-HSA-111997 | 5.433241e-03 | 2.265 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.962370e-03 | 2.304 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 6.084652e-03 | 2.216 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 6.277578e-03 | 2.202 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 6.342744e-03 | 2.198 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 6.397821e-03 | 2.194 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 6.408325e-03 | 2.193 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 6.480457e-03 | 2.188 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 7.145948e-03 | 2.146 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 7.290089e-03 | 2.137 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 7.290089e-03 | 2.137 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 7.290089e-03 | 2.137 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 7.379396e-03 | 2.132 | 1 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 7.662902e-03 | 2.116 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 7.689677e-03 | 2.114 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 7.689677e-03 | 2.114 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.689677e-03 | 2.114 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 8.255338e-03 | 2.083 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 8.308410e-03 | 2.080 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 8.308410e-03 | 2.080 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 8.316883e-03 | 2.080 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 8.316883e-03 | 2.080 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 8.316883e-03 | 2.080 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 8.316883e-03 | 2.080 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 8.494259e-03 | 2.071 | 1 | 1 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 8.578867e-03 | 2.067 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 8.578867e-03 | 2.067 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 8.578867e-03 | 2.067 | 1 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 8.658440e-03 | 2.063 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.658440e-03 | 2.063 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 8.709259e-03 | 2.060 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 8.802805e-03 | 2.055 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 9.065756e-03 | 2.043 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 9.065756e-03 | 2.043 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 9.635480e-03 | 2.016 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 9.635480e-03 | 2.016 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 9.635480e-03 | 2.016 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 9.635480e-03 | 2.016 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 1.000722e-02 | 2.000 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.020905e-02 | 1.991 | 1 | 1 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.049643e-02 | 1.979 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 1.053738e-02 | 1.977 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 1.062270e-02 | 1.974 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 1.089405e-02 | 1.963 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 1.121910e-02 | 1.950 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 1.121910e-02 | 1.950 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 1.121910e-02 | 1.950 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 1.121910e-02 | 1.950 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.507849e-02 | 1.822 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 1.426476e-02 | 1.846 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.142338e-02 | 1.942 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 1.427286e-02 | 1.845 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 1.427286e-02 | 1.845 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 1.262763e-02 | 1.899 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 1.262763e-02 | 1.899 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 1.262763e-02 | 1.899 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 1.338484e-02 | 1.873 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 1.236490e-02 | 1.908 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.511863e-02 | 1.820 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.403546e-02 | 1.853 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.433573e-02 | 1.844 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 1.338484e-02 | 1.873 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 1.338484e-02 | 1.873 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 1.376521e-02 | 1.861 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.403546e-02 | 1.853 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 1.427286e-02 | 1.845 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 1.426476e-02 | 1.846 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.301722e-02 | 1.885 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.222197e-02 | 1.913 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 1.142338e-02 | 1.942 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.142338e-02 | 1.942 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.324494e-02 | 1.878 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.433573e-02 | 1.844 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 1.507590e-02 | 1.822 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 1.525080e-02 | 1.817 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.525080e-02 | 1.817 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 1.525080e-02 | 1.817 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 1.543309e-02 | 1.812 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.557219e-02 | 1.808 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.557219e-02 | 1.808 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 1.560053e-02 | 1.807 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 1.587242e-02 | 1.799 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 1.627182e-02 | 1.789 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 1.695910e-02 | 1.771 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 1.740260e-02 | 1.759 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.781018e-02 | 1.749 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.786187e-02 | 1.748 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.812334e-02 | 1.742 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.812334e-02 | 1.742 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.812334e-02 | 1.742 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.812334e-02 | 1.742 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.812334e-02 | 1.742 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.812334e-02 | 1.742 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.841749e-02 | 1.735 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 1.971942e-02 | 1.705 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 1.985153e-02 | 1.702 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 1.985153e-02 | 1.702 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.007719e-02 | 1.697 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 2.010080e-02 | 1.697 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 2.039835e-02 | 1.690 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 2.039835e-02 | 1.690 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 2.159444e-02 | 1.666 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 2.159444e-02 | 1.666 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 2.161650e-02 | 1.665 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 2.225646e-02 | 1.653 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 2.225646e-02 | 1.653 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 2.232095e-02 | 1.651 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.232095e-02 | 1.651 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 2.232095e-02 | 1.651 | 0 | 0 |
| S Phase | R-HSA-69242 | 2.321738e-02 | 1.634 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 2.371347e-02 | 1.625 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 2.419636e-02 | 1.616 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.434358e-02 | 1.614 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 2.454871e-02 | 1.610 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 2.477362e-02 | 1.606 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.502204e-02 | 1.602 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 2.509926e-02 | 1.600 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 2.518940e-02 | 1.599 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 2.527754e-02 | 1.597 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 2.527754e-02 | 1.597 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 2.527754e-02 | 1.597 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 2.527754e-02 | 1.597 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 2.557176e-02 | 1.592 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 2.557176e-02 | 1.592 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 2.645691e-02 | 1.577 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.645691e-02 | 1.577 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 2.645691e-02 | 1.577 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 2.645691e-02 | 1.577 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 2.679641e-02 | 1.572 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 2.689238e-02 | 1.570 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.689238e-02 | 1.570 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 2.721715e-02 | 1.565 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 2.721715e-02 | 1.565 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 2.721715e-02 | 1.565 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 2.721715e-02 | 1.565 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 2.825036e-02 | 1.549 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 2.885793e-02 | 1.540 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.915507e-02 | 1.535 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 2.915507e-02 | 1.535 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 2.964194e-02 | 1.528 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.008311e-02 | 1.522 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 3.025571e-02 | 1.519 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 3.063321e-02 | 1.514 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 3.091817e-02 | 1.510 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 3.151574e-02 | 1.501 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 3.157117e-02 | 1.501 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 3.219694e-02 | 1.492 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 3.219694e-02 | 1.492 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 3.327654e-02 | 1.478 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 3.345143e-02 | 1.476 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 3.353086e-02 | 1.475 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 3.415473e-02 | 1.467 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 3.415473e-02 | 1.467 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 3.415473e-02 | 1.467 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 3.418052e-02 | 1.466 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 3.418052e-02 | 1.466 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 3.481814e-02 | 1.458 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.815936e-02 | 1.418 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 3.569628e-02 | 1.447 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 3.569628e-02 | 1.447 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 3.569628e-02 | 1.447 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 3.569628e-02 | 1.447 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 4.952428e-02 | 1.305 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 4.952428e-02 | 1.305 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 3.876464e-02 | 1.412 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 3.876464e-02 | 1.412 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 4.687983e-02 | 1.329 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 3.622933e-02 | 1.441 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 3.622933e-02 | 1.441 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 4.190425e-02 | 1.378 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 3.833242e-02 | 1.416 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 5.169058e-02 | 1.287 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 4.542358e-02 | 1.343 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 4.542358e-02 | 1.343 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 4.399170e-02 | 1.357 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 5.249590e-02 | 1.280 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 3.566133e-02 | 1.448 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 3.828101e-02 | 1.417 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 5.169058e-02 | 1.287 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 3.969842e-02 | 1.401 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 4.545599e-02 | 1.342 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 4.952428e-02 | 1.305 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 4.545599e-02 | 1.342 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 4.687983e-02 | 1.329 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 3.506049e-02 | 1.455 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 5.186312e-02 | 1.285 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 4.967953e-02 | 1.304 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 4.967953e-02 | 1.304 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 4.967953e-02 | 1.304 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 4.967953e-02 | 1.304 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 4.852735e-02 | 1.314 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 4.399170e-02 | 1.357 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.687983e-02 | 1.329 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 3.506049e-02 | 1.455 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 3.917092e-02 | 1.407 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 4.572071e-02 | 1.340 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 3.876464e-02 | 1.412 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 4.952428e-02 | 1.305 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 4.503920e-02 | 1.346 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 3.833242e-02 | 1.416 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 4.277654e-02 | 1.369 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 4.545599e-02 | 1.342 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 4.677380e-02 | 1.330 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 4.364228e-02 | 1.360 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 5.194572e-02 | 1.284 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 3.566133e-02 | 1.448 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 4.919417e-02 | 1.308 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 4.967953e-02 | 1.304 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 4.967953e-02 | 1.304 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 4.277654e-02 | 1.369 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 5.167238e-02 | 1.287 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 3.747198e-02 | 1.426 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 4.933206e-02 | 1.307 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 3.833242e-02 | 1.416 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.912853e-02 | 1.309 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 4.233882e-02 | 1.373 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 3.506049e-02 | 1.455 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 5.249590e-02 | 1.280 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 4.926601e-02 | 1.307 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 5.249590e-02 | 1.280 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 3.523072e-02 | 1.453 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 5.395372e-02 | 1.268 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 5.419971e-02 | 1.266 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 5.478687e-02 | 1.261 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 5.478687e-02 | 1.261 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 5.478687e-02 | 1.261 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 5.478687e-02 | 1.261 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 5.491115e-02 | 1.260 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 5.592840e-02 | 1.252 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 5.592840e-02 | 1.252 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 5.592840e-02 | 1.252 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 5.592840e-02 | 1.252 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 5.630504e-02 | 1.249 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 5.664074e-02 | 1.247 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 5.863895e-02 | 1.232 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 5.863895e-02 | 1.232 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 5.888851e-02 | 1.230 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 5.895312e-02 | 1.229 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 5.907832e-02 | 1.229 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 5.910318e-02 | 1.228 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 5.937111e-02 | 1.226 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 5.964536e-02 | 1.224 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 6.066024e-02 | 1.217 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 6.066024e-02 | 1.217 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 6.077684e-02 | 1.216 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 6.077684e-02 | 1.216 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 6.077684e-02 | 1.216 | 1 | 1 |
| FLT3 Signaling | R-HSA-9607240 | 6.077684e-02 | 1.216 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 6.204170e-02 | 1.207 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 6.204170e-02 | 1.207 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 6.204170e-02 | 1.207 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 6.204170e-02 | 1.207 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 6.204170e-02 | 1.207 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 6.225007e-02 | 1.206 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 6.352097e-02 | 1.197 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 6.517432e-02 | 1.186 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 6.554367e-02 | 1.183 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 6.556692e-02 | 1.183 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 6.556692e-02 | 1.183 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 6.591204e-02 | 1.181 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 6.591204e-02 | 1.181 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 6.591204e-02 | 1.181 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 6.591204e-02 | 1.181 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 6.591204e-02 | 1.181 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 6.691724e-02 | 1.174 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 6.745959e-02 | 1.171 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 6.745959e-02 | 1.171 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 6.907418e-02 | 1.161 | 1 | 1 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 6.907418e-02 | 1.161 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 6.913775e-02 | 1.160 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 6.913775e-02 | 1.160 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 6.953591e-02 | 1.158 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 7.016612e-02 | 1.154 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 7.016612e-02 | 1.154 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 7.016612e-02 | 1.154 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 7.047915e-02 | 1.152 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 7.066597e-02 | 1.151 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 7.081032e-02 | 1.150 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 7.154381e-02 | 1.145 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 7.333630e-02 | 1.135 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 7.544469e-02 | 1.122 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 7.671073e-02 | 1.115 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 7.682293e-02 | 1.115 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 7.850806e-02 | 1.105 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 7.865440e-02 | 1.104 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 7.865440e-02 | 1.104 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 7.865440e-02 | 1.104 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 8.117702e-02 | 1.091 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 8.117702e-02 | 1.091 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 8.283674e-02 | 1.082 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 8.283674e-02 | 1.082 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 8.283674e-02 | 1.082 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 8.283674e-02 | 1.082 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 8.283674e-02 | 1.082 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 8.283674e-02 | 1.082 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 8.283674e-02 | 1.082 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 8.283674e-02 | 1.082 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 8.283674e-02 | 1.082 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 8.283674e-02 | 1.082 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 8.283674e-02 | 1.082 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 8.366791e-02 | 1.077 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 8.366791e-02 | 1.077 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 8.366791e-02 | 1.077 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 8.366791e-02 | 1.077 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 8.476139e-02 | 1.072 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 8.476139e-02 | 1.072 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 8.661920e-02 | 1.062 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 8.661920e-02 | 1.062 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 8.661920e-02 | 1.062 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 8.771298e-02 | 1.057 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 8.771298e-02 | 1.057 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 8.771298e-02 | 1.057 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.771298e-02 | 1.057 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 8.864438e-02 | 1.052 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 8.864438e-02 | 1.052 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 8.864438e-02 | 1.052 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 8.864438e-02 | 1.052 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 8.864438e-02 | 1.052 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 8.864438e-02 | 1.052 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 8.879466e-02 | 1.052 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 9.073224e-02 | 1.042 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 9.073224e-02 | 1.042 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.136073e-02 | 1.039 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 9.136073e-02 | 1.039 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 9.136073e-02 | 1.039 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 9.275400e-02 | 1.033 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 9.299014e-02 | 1.032 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 9.299014e-02 | 1.032 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 9.299014e-02 | 1.032 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 9.371673e-02 | 1.028 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.682074e-02 | 1.014 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 9.682074e-02 | 1.014 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 9.682074e-02 | 1.014 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 9.682074e-02 | 1.014 | 0 | 0 |
| Defective SFTPA2 causes IPF | R-HSA-5687868 | 9.683276e-02 | 1.014 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 9.783289e-02 | 1.010 | 1 | 1 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 9.783289e-02 | 1.010 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.842941e-01 | 0.734 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.842941e-01 | 0.734 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.842941e-01 | 0.734 | 0 | 0 |
| Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) | R-HSA-5619043 | 1.842941e-01 | 0.734 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.255346e-01 | 0.901 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.255346e-01 | 0.901 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.255346e-01 | 0.901 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 1.602832e-01 | 0.795 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.602832e-01 | 0.795 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.602832e-01 | 0.795 | 0 | 0 |
| RSK activation | R-HSA-444257 | 1.036416e-01 | 0.984 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 1.252838e-01 | 0.902 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.252838e-01 | 0.902 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 1.252838e-01 | 0.902 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 1.965046e-01 | 0.707 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 1.965046e-01 | 0.707 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.965046e-01 | 0.707 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 1.965046e-01 | 0.707 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.965046e-01 | 0.707 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 1.965046e-01 | 0.707 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 1.483806e-01 | 0.829 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 1.483806e-01 | 0.829 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 1.483806e-01 | 0.829 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 1.727153e-01 | 0.763 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.727153e-01 | 0.763 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.727153e-01 | 0.763 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.727153e-01 | 0.763 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.312400e-01 | 0.882 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.312400e-01 | 0.882 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.312400e-01 | 0.882 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 1.149118e-01 | 0.940 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.149118e-01 | 0.940 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.494834e-01 | 0.825 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 1.686298e-01 | 0.773 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.686298e-01 | 0.773 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.120422e-01 | 0.951 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.885806e-01 | 0.725 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.885806e-01 | 0.725 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.885806e-01 | 0.725 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.075172e-01 | 0.969 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 1.182431e-01 | 0.927 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 1.508229e-01 | 0.822 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 1.052526e-01 | 0.978 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 9.892605e-02 | 1.005 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 1.140860e-01 | 0.943 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 1.429294e-01 | 0.845 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 1.901535e-01 | 0.721 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.901535e-01 | 0.721 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 1.750889e-01 | 0.757 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 1.736694e-01 | 0.760 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.521422e-01 | 0.818 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 1.216771e-01 | 0.915 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 1.140860e-01 | 0.943 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 1.147181e-01 | 0.940 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 1.147181e-01 | 0.940 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 1.686298e-01 | 0.773 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 1.885806e-01 | 0.725 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.052526e-01 | 0.978 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.602832e-01 | 0.795 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 1.965046e-01 | 0.707 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.483806e-01 | 0.829 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 1.947073e-01 | 0.711 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 1.139938e-01 | 0.943 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 1.013514e-01 | 0.994 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.657270e-01 | 0.781 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 1.255346e-01 | 0.901 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 1.555063e-01 | 0.808 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 1.237421e-01 | 0.907 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.685235e-01 | 0.773 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 1.409590e-01 | 0.851 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 1.070946e-01 | 0.970 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.233150e-01 | 0.909 | 1 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 1.216771e-01 | 0.915 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 1.216771e-01 | 0.915 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 1.412716e-01 | 0.850 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 1.412716e-01 | 0.850 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.074696e-01 | 0.969 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 1.939675e-01 | 0.712 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 1.245534e-01 | 0.905 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 1.252838e-01 | 0.902 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 1.692132e-01 | 0.772 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 1.635091e-01 | 0.786 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 1.149118e-01 | 0.940 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 1.022874e-01 | 0.990 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 1.013514e-01 | 0.994 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.075172e-01 | 0.969 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 1.022874e-01 | 0.990 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 1.662775e-01 | 0.779 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 1.540891e-01 | 0.812 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.412716e-01 | 0.850 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.295002e-01 | 0.888 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 1.209027e-01 | 0.918 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 1.560655e-01 | 0.807 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 9.892605e-02 | 1.005 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.022874e-01 | 0.990 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 1.086417e-01 | 0.964 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.842941e-01 | 0.734 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 1.602832e-01 | 0.795 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 1.965046e-01 | 0.707 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 1.965046e-01 | 0.707 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.727153e-01 | 0.763 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 1.292865e-01 | 0.888 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 1.885806e-01 | 0.725 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 1.117531e-01 | 0.952 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 1.117531e-01 | 0.952 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 1.535379e-01 | 0.814 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 1.662775e-01 | 0.779 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 1.777547e-01 | 0.750 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 1.777547e-01 | 0.750 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 1.864892e-01 | 0.729 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 1.022874e-01 | 0.990 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 1.073896e-01 | 0.969 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.777547e-01 | 0.750 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 1.147181e-01 | 0.940 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 1.252838e-01 | 0.902 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.252838e-01 | 0.902 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 1.727153e-01 | 0.763 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 1.120422e-01 | 0.951 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 9.949234e-02 | 1.002 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.733884e-01 | 0.761 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.334322e-01 | 0.875 | 1 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.036416e-01 | 0.984 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 1.312400e-01 | 0.882 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 1.602954e-01 | 0.795 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 1.182431e-01 | 0.927 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 1.182431e-01 | 0.927 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 1.768265e-01 | 0.752 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 1.295002e-01 | 0.888 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 1.295002e-01 | 0.888 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.052526e-01 | 0.978 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 1.532956e-01 | 0.814 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.932522e-01 | 0.714 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 1.295002e-01 | 0.888 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 1.662529e-01 | 0.779 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 1.602954e-01 | 0.795 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 1.255346e-01 | 0.901 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.965046e-01 | 0.707 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 1.939675e-01 | 0.712 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 1.736694e-01 | 0.760 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 1.137202e-01 | 0.944 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.139938e-01 | 0.943 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.780921e-01 | 0.749 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 1.151204e-01 | 0.939 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.117531e-01 | 0.952 | 1 | 1 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.243496e-01 | 0.905 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.435906e-01 | 0.843 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 1.602832e-01 | 0.795 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 1.252838e-01 | 0.902 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.780939e-01 | 0.749 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.768265e-01 | 0.752 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 1.483806e-01 | 0.829 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 1.965046e-01 | 0.707 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.003885e-01 | 0.998 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 1.149118e-01 | 0.940 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.494834e-01 | 0.825 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.885806e-01 | 0.725 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 1.980734e-01 | 0.703 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 1.980734e-01 | 0.703 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.980734e-01 | 0.703 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.980734e-01 | 0.703 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 1.985503e-01 | 0.702 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.985503e-01 | 0.702 | 0 | 0 |
| Disease | R-HSA-1643685 | 2.026407e-01 | 0.693 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 2.029037e-01 | 0.693 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 2.043748e-01 | 0.690 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 2.070899e-01 | 0.684 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 2.086560e-01 | 0.681 | 0 | 0 |
| PKA activation | R-HSA-163615 | 2.092351e-01 | 0.679 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.092351e-01 | 0.679 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 2.092351e-01 | 0.679 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 2.092351e-01 | 0.679 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.092351e-01 | 0.679 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 2.102223e-01 | 0.677 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 2.103045e-01 | 0.677 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 2.103045e-01 | 0.677 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 2.103045e-01 | 0.677 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.116592e-01 | 0.674 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 2.159842e-01 | 0.666 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.214683e-01 | 0.655 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 2.214683e-01 | 0.655 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 2.242471e-01 | 0.649 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 2.242471e-01 | 0.649 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 2.242471e-01 | 0.649 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 2.242471e-01 | 0.649 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 2.242471e-01 | 0.649 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 2.242471e-01 | 0.649 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.242471e-01 | 0.649 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 2.275400e-01 | 0.643 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 2.293731e-01 | 0.639 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 2.293731e-01 | 0.639 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 2.293731e-01 | 0.639 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 2.298408e-01 | 0.639 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 2.298408e-01 | 0.639 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 2.300793e-01 | 0.638 | 1 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 2.304913e-01 | 0.637 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 2.304913e-01 | 0.637 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.335883e-01 | 0.632 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 2.335883e-01 | 0.632 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 2.335883e-01 | 0.632 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 2.335883e-01 | 0.632 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 2.350884e-01 | 0.629 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 2.361856e-01 | 0.627 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 2.484506e-01 | 0.605 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 2.484506e-01 | 0.605 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 2.510380e-01 | 0.600 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 2.512112e-01 | 0.600 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 2.513488e-01 | 0.600 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 2.522482e-01 | 0.598 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 2.522482e-01 | 0.598 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 2.569840e-01 | 0.590 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 2.594419e-01 | 0.586 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 2.623837e-01 | 0.581 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 2.632905e-01 | 0.580 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 2.632905e-01 | 0.580 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) | R-HSA-5619045 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 2.632905e-01 | 0.580 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 2.632905e-01 | 0.580 | 0 | 0 |
| MyD88 deficiency (TLR5) | R-HSA-5602680 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.632905e-01 | 0.580 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.632905e-01 | 0.580 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective SLC34A2 causes PALM | R-HSA-5687583 | 2.632905e-01 | 0.580 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.632905e-01 | 0.580 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.710279e-01 | 0.567 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.710279e-01 | 0.567 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 2.710279e-01 | 0.567 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 2.710279e-01 | 0.567 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 2.710279e-01 | 0.567 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 2.710279e-01 | 0.567 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 2.710279e-01 | 0.567 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 2.710279e-01 | 0.567 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 2.710279e-01 | 0.567 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.710279e-01 | 0.567 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 2.711583e-01 | 0.567 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 2.741961e-01 | 0.562 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.744062e-01 | 0.562 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 2.744062e-01 | 0.562 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 2.744062e-01 | 0.562 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 2.744062e-01 | 0.562 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.744062e-01 | 0.562 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 2.744062e-01 | 0.562 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 2.744062e-01 | 0.562 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 2.762764e-01 | 0.559 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 2.764624e-01 | 0.558 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 2.764624e-01 | 0.558 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 2.782593e-01 | 0.556 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 2.820624e-01 | 0.550 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 2.820624e-01 | 0.550 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 2.867067e-01 | 0.543 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.867067e-01 | 0.543 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 2.888820e-01 | 0.539 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 2.968687e-01 | 0.527 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 2.968687e-01 | 0.527 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 2.968687e-01 | 0.527 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 2.978244e-01 | 0.526 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 2.985382e-01 | 0.525 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 3.057376e-01 | 0.515 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 3.057376e-01 | 0.515 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 3.062303e-01 | 0.514 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 3.062303e-01 | 0.514 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 3.084071e-01 | 0.511 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 3.084071e-01 | 0.511 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 3.084071e-01 | 0.511 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 3.084071e-01 | 0.511 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 3.091911e-01 | 0.510 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.108455e-01 | 0.507 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 3.137683e-01 | 0.503 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 3.145200e-01 | 0.502 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 3.195426e-01 | 0.495 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 3.195426e-01 | 0.495 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 3.275867e-01 | 0.485 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 3.275867e-01 | 0.485 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 3.288493e-01 | 0.483 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 3.288493e-01 | 0.483 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 3.288493e-01 | 0.483 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 3.297412e-01 | 0.482 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 3.297412e-01 | 0.482 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 3.333130e-01 | 0.477 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 3.333130e-01 | 0.477 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 3.333130e-01 | 0.477 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 3.333130e-01 | 0.477 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.346407e-01 | 0.475 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 3.346407e-01 | 0.475 | 0 | 0 |
| Defective ALG9 causes CDG-1l | R-HSA-4720454 | 3.346407e-01 | 0.475 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 3.346407e-01 | 0.475 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.346407e-01 | 0.475 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 3.346407e-01 | 0.475 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 3.346407e-01 | 0.475 | 0 | 0 |
| tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis | R-HSA-9708296 | 3.346407e-01 | 0.475 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.346407e-01 | 0.475 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 3.359434e-01 | 0.474 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 3.407585e-01 | 0.468 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 3.423390e-01 | 0.466 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 3.423390e-01 | 0.466 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 3.423390e-01 | 0.466 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 3.424862e-01 | 0.465 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 3.447939e-01 | 0.462 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 3.453868e-01 | 0.462 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 3.453868e-01 | 0.462 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 3.453868e-01 | 0.462 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 3.453868e-01 | 0.462 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 3.453868e-01 | 0.462 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 3.453868e-01 | 0.462 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 3.453868e-01 | 0.462 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 3.453868e-01 | 0.462 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 3.453868e-01 | 0.462 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 3.453868e-01 | 0.462 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 3.453868e-01 | 0.462 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 3.453868e-01 | 0.462 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 3.453868e-01 | 0.462 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 3.453868e-01 | 0.462 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.453868e-01 | 0.462 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 3.453868e-01 | 0.462 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 3.460746e-01 | 0.461 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.466130e-01 | 0.460 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 3.466130e-01 | 0.460 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 3.466130e-01 | 0.460 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 3.466130e-01 | 0.460 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 3.466130e-01 | 0.460 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 3.478842e-01 | 0.459 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.608404e-01 | 0.443 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 3.608404e-01 | 0.443 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 3.608404e-01 | 0.443 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 3.608404e-01 | 0.443 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 3.608404e-01 | 0.443 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 3.608404e-01 | 0.443 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 3.608404e-01 | 0.443 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 3.651740e-01 | 0.438 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 3.651740e-01 | 0.438 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.656727e-01 | 0.437 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 3.807375e-01 | 0.419 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 3.807375e-01 | 0.419 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.816938e-01 | 0.418 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 3.816938e-01 | 0.418 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 3.816938e-01 | 0.418 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 3.816938e-01 | 0.418 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 3.816938e-01 | 0.418 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.816938e-01 | 0.418 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 3.816938e-01 | 0.418 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 3.823477e-01 | 0.418 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.853588e-01 | 0.414 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 3.855909e-01 | 0.414 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 3.855909e-01 | 0.414 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 3.879687e-01 | 0.411 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 3.879687e-01 | 0.411 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 3.924617e-01 | 0.406 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 3.990845e-01 | 0.399 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 3.990845e-01 | 0.399 | 0 | 0 |
| Defective ABCC2 causes DJS | R-HSA-5679001 | 3.990845e-01 | 0.399 | 0 | 0 |
| Defective ABCA1 causes TGD | R-HSA-5682113 | 3.990845e-01 | 0.399 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 3.990845e-01 | 0.399 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 3.990845e-01 | 0.399 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.990845e-01 | 0.399 | 0 | 0 |
| Type II Na+/Pi cotransporters | R-HSA-427589 | 3.990845e-01 | 0.399 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.990845e-01 | 0.399 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 3.990845e-01 | 0.399 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 4.038280e-01 | 0.394 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 4.106497e-01 | 0.387 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 4.106497e-01 | 0.387 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 4.106497e-01 | 0.387 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 4.114992e-01 | 0.386 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 4.152427e-01 | 0.382 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 4.171119e-01 | 0.380 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 4.171119e-01 | 0.380 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 4.171119e-01 | 0.380 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 4.171119e-01 | 0.380 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 4.171119e-01 | 0.380 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 4.181029e-01 | 0.379 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 4.205575e-01 | 0.376 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 4.331493e-01 | 0.363 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 4.331493e-01 | 0.363 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 4.331493e-01 | 0.363 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 4.331493e-01 | 0.363 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.331493e-01 | 0.363 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 4.331493e-01 | 0.363 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 4.418983e-01 | 0.355 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 4.418983e-01 | 0.355 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 4.418983e-01 | 0.355 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 4.418983e-01 | 0.355 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 4.494243e-01 | 0.347 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.514726e-01 | 0.345 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 4.514726e-01 | 0.345 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 4.514726e-01 | 0.345 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 4.514726e-01 | 0.345 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 4.514726e-01 | 0.345 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 4.514726e-01 | 0.345 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 4.535926e-01 | 0.343 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 4.535926e-01 | 0.343 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 4.554055e-01 | 0.342 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 4.554055e-01 | 0.342 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 4.554055e-01 | 0.342 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 4.572900e-01 | 0.340 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 4.572900e-01 | 0.340 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 4.572900e-01 | 0.340 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 4.572900e-01 | 0.340 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.572900e-01 | 0.340 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.572900e-01 | 0.340 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 4.572900e-01 | 0.340 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 4.572900e-01 | 0.340 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 4.572900e-01 | 0.340 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 4.572900e-01 | 0.340 | 0 | 0 |
| Transmission across Electrical Synapses | R-HSA-112307 | 4.572900e-01 | 0.340 | 0 | 0 |
| Electric Transmission Across Gap Junctions | R-HSA-112303 | 4.572900e-01 | 0.340 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 4.572900e-01 | 0.340 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 4.572900e-01 | 0.340 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 4.572900e-01 | 0.340 | 0 | 0 |
| Toxicity of tetanus toxin (tetX) | R-HSA-5250982 | 4.572900e-01 | 0.340 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 4.659123e-01 | 0.332 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 4.680668e-01 | 0.330 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.680668e-01 | 0.330 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 4.680668e-01 | 0.330 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 4.680668e-01 | 0.330 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 4.837272e-01 | 0.315 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 4.846487e-01 | 0.315 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 4.846487e-01 | 0.315 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 4.846487e-01 | 0.315 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 4.846487e-01 | 0.315 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 4.846487e-01 | 0.315 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 4.846487e-01 | 0.315 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 4.846487e-01 | 0.315 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 4.908203e-01 | 0.309 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 4.957393e-01 | 0.305 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 5.098607e-01 | 0.293 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 5.098607e-01 | 0.293 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 5.098607e-01 | 0.293 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 5.098607e-01 | 0.293 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 5.098607e-01 | 0.293 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 5.098607e-01 | 0.293 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 5.098607e-01 | 0.293 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 5.098607e-01 | 0.293 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 5.098607e-01 | 0.293 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 5.098607e-01 | 0.293 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 5.098607e-01 | 0.293 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 5.098607e-01 | 0.293 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 5.098607e-01 | 0.293 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 5.098607e-01 | 0.293 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 5.098607e-01 | 0.293 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 5.141830e-01 | 0.289 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 5.165472e-01 | 0.287 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 5.165472e-01 | 0.287 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 5.165472e-01 | 0.287 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 5.165472e-01 | 0.287 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 5.165472e-01 | 0.287 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 5.165472e-01 | 0.287 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 5.186466e-01 | 0.285 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 5.186466e-01 | 0.285 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 5.215247e-01 | 0.283 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 5.318428e-01 | 0.274 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 5.399721e-01 | 0.268 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 5.409534e-01 | 0.267 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 5.409534e-01 | 0.267 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 5.429389e-01 | 0.265 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 5.429389e-01 | 0.265 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 5.471045e-01 | 0.262 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 5.471045e-01 | 0.262 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 5.471045e-01 | 0.262 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 5.471045e-01 | 0.262 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 5.471045e-01 | 0.262 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 5.546705e-01 | 0.256 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 5.546705e-01 | 0.256 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 5.546705e-01 | 0.256 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.573418e-01 | 0.254 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 5.573418e-01 | 0.254 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.573418e-01 | 0.254 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.573418e-01 | 0.254 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 5.573418e-01 | 0.254 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 5.573418e-01 | 0.254 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.573418e-01 | 0.254 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 5.573418e-01 | 0.254 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 5.573418e-01 | 0.254 | 0 | 0 |
| Signaling by MST1 | R-HSA-8852405 | 5.573418e-01 | 0.254 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 5.573418e-01 | 0.254 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 5.580815e-01 | 0.253 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 5.580815e-01 | 0.253 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 5.580815e-01 | 0.253 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 5.610574e-01 | 0.251 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 5.612588e-01 | 0.251 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 5.612588e-01 | 0.251 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 5.645781e-01 | 0.248 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 5.762811e-01 | 0.239 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 5.762811e-01 | 0.239 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 5.810646e-01 | 0.236 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.953604e-01 | 0.225 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.990323e-01 | 0.223 | 0 | 0 |
| Chylomicron clearance | R-HSA-8964026 | 6.002259e-01 | 0.222 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 6.002259e-01 | 0.222 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 6.002259e-01 | 0.222 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 6.002259e-01 | 0.222 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 6.002259e-01 | 0.222 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 6.002259e-01 | 0.222 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 6.002259e-01 | 0.222 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 6.002259e-01 | 0.222 | 0 | 0 |
| Lactose synthesis | R-HSA-5653890 | 6.002259e-01 | 0.222 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 6.002259e-01 | 0.222 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 6.002259e-01 | 0.222 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 6.002259e-01 | 0.222 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 6.002259e-01 | 0.222 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 6.002259e-01 | 0.222 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 6.002259e-01 | 0.222 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 6.003459e-01 | 0.222 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 6.040576e-01 | 0.219 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 6.040576e-01 | 0.219 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 6.040576e-01 | 0.219 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 6.040576e-01 | 0.219 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 6.040576e-01 | 0.219 | 0 | 0 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 6.040576e-01 | 0.219 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 6.040576e-01 | 0.219 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 6.040576e-01 | 0.219 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 6.087961e-01 | 0.216 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 6.101542e-01 | 0.215 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 6.101542e-01 | 0.215 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 6.101542e-01 | 0.215 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 6.113235e-01 | 0.214 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 6.113235e-01 | 0.214 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 6.113235e-01 | 0.214 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 6.190823e-01 | 0.208 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 6.266984e-01 | 0.203 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 6.266984e-01 | 0.203 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 6.300441e-01 | 0.201 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 6.304316e-01 | 0.200 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 6.304316e-01 | 0.200 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 6.325328e-01 | 0.199 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 6.325328e-01 | 0.199 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 6.325328e-01 | 0.199 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 6.372572e-01 | 0.196 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 6.372572e-01 | 0.196 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 6.389577e-01 | 0.195 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 6.389577e-01 | 0.195 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 6.389577e-01 | 0.195 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 6.389577e-01 | 0.195 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 6.389577e-01 | 0.195 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.389577e-01 | 0.195 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 6.389577e-01 | 0.195 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 6.389577e-01 | 0.195 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 6.389577e-01 | 0.195 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 6.389577e-01 | 0.195 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 6.389577e-01 | 0.195 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 6.418753e-01 | 0.193 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 6.428116e-01 | 0.192 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 6.529237e-01 | 0.185 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 6.529237e-01 | 0.185 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 6.529237e-01 | 0.185 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 6.529237e-01 | 0.185 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 6.529237e-01 | 0.185 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 6.548582e-01 | 0.184 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 6.554140e-01 | 0.183 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 6.554140e-01 | 0.183 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 6.554140e-01 | 0.183 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 6.615360e-01 | 0.179 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 6.680805e-01 | 0.175 | 1 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 6.718762e-01 | 0.173 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 6.724908e-01 | 0.172 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 6.724908e-01 | 0.172 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 6.724908e-01 | 0.172 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 6.724908e-01 | 0.172 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 6.724908e-01 | 0.172 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 6.737047e-01 | 0.172 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 6.737047e-01 | 0.172 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.739391e-01 | 0.171 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.739391e-01 | 0.171 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 6.739391e-01 | 0.171 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.739391e-01 | 0.171 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 6.739391e-01 | 0.171 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 6.739391e-01 | 0.171 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 6.739391e-01 | 0.171 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 6.739391e-01 | 0.171 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 6.739391e-01 | 0.171 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 6.739391e-01 | 0.171 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 6.739391e-01 | 0.171 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 6.739391e-01 | 0.171 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 6.739391e-01 | 0.171 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 6.739391e-01 | 0.171 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.739391e-01 | 0.171 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 6.739391e-01 | 0.171 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.739391e-01 | 0.171 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.767039e-01 | 0.170 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 6.767039e-01 | 0.170 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 6.774565e-01 | 0.169 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 6.790269e-01 | 0.168 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 6.790269e-01 | 0.168 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 6.790269e-01 | 0.168 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 6.790269e-01 | 0.168 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 6.790269e-01 | 0.168 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 6.883055e-01 | 0.162 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 6.883055e-01 | 0.162 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 6.912337e-01 | 0.160 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 6.912337e-01 | 0.160 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 7.013011e-01 | 0.154 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 7.013011e-01 | 0.154 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 7.013011e-01 | 0.154 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 7.013011e-01 | 0.154 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 7.013011e-01 | 0.154 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 7.013011e-01 | 0.154 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.027735e-01 | 0.153 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 7.033116e-01 | 0.153 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 7.055329e-01 | 0.151 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 7.055329e-01 | 0.151 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 7.055329e-01 | 0.151 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 7.055329e-01 | 0.151 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 7.055329e-01 | 0.151 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 7.072325e-01 | 0.150 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 7.091567e-01 | 0.149 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 7.091567e-01 | 0.149 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 7.091567e-01 | 0.149 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 7.091567e-01 | 0.149 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 7.091567e-01 | 0.149 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 7.099348e-01 | 0.149 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 7.160463e-01 | 0.145 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 7.222742e-01 | 0.141 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 7.222742e-01 | 0.141 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 7.222742e-01 | 0.141 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 7.222742e-01 | 0.141 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 7.222742e-01 | 0.141 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 7.262686e-01 | 0.139 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 7.340476e-01 | 0.134 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 7.340672e-01 | 0.134 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 7.340672e-01 | 0.134 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 7.340672e-01 | 0.134 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 7.340672e-01 | 0.134 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 7.340672e-01 | 0.134 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 7.340672e-01 | 0.134 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 7.340672e-01 | 0.134 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 7.340672e-01 | 0.134 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 7.340672e-01 | 0.134 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 7.340672e-01 | 0.134 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 7.385573e-01 | 0.132 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 7.403680e-01 | 0.131 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 7.419893e-01 | 0.130 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 7.419893e-01 | 0.130 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 7.419893e-01 | 0.130 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 7.425814e-01 | 0.129 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 7.425814e-01 | 0.129 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 7.429041e-01 | 0.129 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 7.519549e-01 | 0.124 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 7.531240e-01 | 0.123 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 7.576614e-01 | 0.121 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 7.581101e-01 | 0.120 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 7.596539e-01 | 0.119 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 7.598380e-01 | 0.119 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.598380e-01 | 0.119 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.598380e-01 | 0.119 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 7.598380e-01 | 0.119 | 0 | 0 |
| Vitamin B1 (thiamin) metabolism | R-HSA-196819 | 7.598380e-01 | 0.119 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.598380e-01 | 0.119 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.598380e-01 | 0.119 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.598380e-01 | 0.119 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 7.604931e-01 | 0.119 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 7.604931e-01 | 0.119 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 7.604931e-01 | 0.119 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 7.616170e-01 | 0.118 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 7.668905e-01 | 0.115 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 7.728724e-01 | 0.112 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 7.728724e-01 | 0.112 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 7.728724e-01 | 0.112 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 7.745437e-01 | 0.111 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 7.775738e-01 | 0.109 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 7.778353e-01 | 0.109 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 7.778353e-01 | 0.109 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 7.778353e-01 | 0.109 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.778353e-01 | 0.109 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 7.778353e-01 | 0.109 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 7.778353e-01 | 0.109 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 7.778353e-01 | 0.109 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 7.778353e-01 | 0.109 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.831127e-01 | 0.106 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 7.831127e-01 | 0.106 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.831127e-01 | 0.106 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.831127e-01 | 0.106 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 7.844401e-01 | 0.105 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 7.868882e-01 | 0.104 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 7.868882e-01 | 0.104 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 7.868882e-01 | 0.104 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 7.899919e-01 | 0.102 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 7.932979e-01 | 0.101 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 7.940671e-01 | 0.100 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 7.940671e-01 | 0.100 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 7.987307e-01 | 0.098 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 8.001787e-01 | 0.097 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 8.001787e-01 | 0.097 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 8.010263e-01 | 0.096 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 8.024985e-01 | 0.096 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 8.041331e-01 | 0.095 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 8.041331e-01 | 0.095 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 8.041331e-01 | 0.095 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 8.041331e-01 | 0.095 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.041331e-01 | 0.095 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 8.041331e-01 | 0.095 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.041331e-01 | 0.095 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 8.041331e-01 | 0.095 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 8.041331e-01 | 0.095 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 8.041331e-01 | 0.095 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.041331e-01 | 0.095 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 8.092408e-01 | 0.092 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 8.092408e-01 | 0.092 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 8.092408e-01 | 0.092 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 8.108750e-01 | 0.091 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 8.108750e-01 | 0.091 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 8.111698e-01 | 0.091 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 8.127669e-01 | 0.090 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.206777e-01 | 0.086 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.231174e-01 | 0.085 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 8.231174e-01 | 0.085 | 0 | 0 |
| Mtb iron assimilation by chelation | R-HSA-1222449 | 8.231174e-01 | 0.085 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 8.231174e-01 | 0.085 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.231174e-01 | 0.085 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 8.234090e-01 | 0.084 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 8.234090e-01 | 0.084 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 8.234090e-01 | 0.084 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 8.234090e-01 | 0.084 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.234090e-01 | 0.084 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 8.246765e-01 | 0.084 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 8.265539e-01 | 0.083 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 8.290422e-01 | 0.081 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 8.359322e-01 | 0.078 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 8.359322e-01 | 0.078 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 8.366240e-01 | 0.077 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 8.366240e-01 | 0.077 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 8.366240e-01 | 0.077 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 8.366240e-01 | 0.077 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.383660e-01 | 0.077 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.391505e-01 | 0.076 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.402626e-01 | 0.076 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.402626e-01 | 0.076 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.402626e-01 | 0.076 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.402626e-01 | 0.076 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.402626e-01 | 0.076 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 8.402626e-01 | 0.076 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 8.402626e-01 | 0.076 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.402626e-01 | 0.076 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 8.402626e-01 | 0.076 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 8.402626e-01 | 0.076 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.407897e-01 | 0.075 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 8.413597e-01 | 0.075 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 8.465591e-01 | 0.072 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 8.465591e-01 | 0.072 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 8.465591e-01 | 0.072 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 8.483827e-01 | 0.071 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 8.487910e-01 | 0.071 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.489374e-01 | 0.071 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 8.489374e-01 | 0.071 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.495589e-01 | 0.071 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 8.500715e-01 | 0.071 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 8.557469e-01 | 0.068 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 8.557469e-01 | 0.068 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.557469e-01 | 0.068 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 8.557469e-01 | 0.068 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 8.557469e-01 | 0.068 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 8.557469e-01 | 0.068 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 8.557469e-01 | 0.068 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 8.557469e-01 | 0.068 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 8.557469e-01 | 0.068 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 8.601466e-01 | 0.065 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 8.603999e-01 | 0.065 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 8.603999e-01 | 0.065 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 8.625026e-01 | 0.064 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 8.625026e-01 | 0.064 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 8.626471e-01 | 0.064 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 8.660278e-01 | 0.062 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 8.695238e-01 | 0.061 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.697310e-01 | 0.061 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.697310e-01 | 0.061 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.697310e-01 | 0.061 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 8.697310e-01 | 0.061 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 8.697310e-01 | 0.061 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 8.697310e-01 | 0.061 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.697310e-01 | 0.061 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 8.697310e-01 | 0.061 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 8.697310e-01 | 0.061 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 8.710606e-01 | 0.060 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 8.710606e-01 | 0.060 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 8.710606e-01 | 0.060 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 8.737030e-01 | 0.059 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 8.737030e-01 | 0.059 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 8.737030e-01 | 0.059 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.749206e-01 | 0.058 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 8.749206e-01 | 0.058 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 8.762436e-01 | 0.057 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 8.792059e-01 | 0.056 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 8.809671e-01 | 0.055 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 8.809671e-01 | 0.055 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 8.809671e-01 | 0.055 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 8.820295e-01 | 0.055 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 8.823602e-01 | 0.054 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 8.823602e-01 | 0.054 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 8.823602e-01 | 0.054 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 8.823602e-01 | 0.054 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 8.823602e-01 | 0.054 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 8.823602e-01 | 0.054 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 8.823602e-01 | 0.054 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 8.823602e-01 | 0.054 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 8.823602e-01 | 0.054 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 8.823602e-01 | 0.054 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.823602e-01 | 0.054 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 8.827333e-01 | 0.054 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 8.829503e-01 | 0.054 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 8.889017e-01 | 0.051 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.937657e-01 | 0.049 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 8.937657e-01 | 0.049 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.937657e-01 | 0.049 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.937657e-01 | 0.049 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 8.937657e-01 | 0.049 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 8.937657e-01 | 0.049 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 8.937657e-01 | 0.049 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 8.937657e-01 | 0.049 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 8.937657e-01 | 0.049 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 8.937657e-01 | 0.049 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.967789e-01 | 0.047 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.985925e-01 | 0.046 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 8.987001e-01 | 0.046 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.029900e-01 | 0.044 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.029900e-01 | 0.044 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 9.040660e-01 | 0.044 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 9.040660e-01 | 0.044 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 9.040660e-01 | 0.044 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 9.066129e-01 | 0.043 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 9.066129e-01 | 0.043 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 9.066129e-01 | 0.043 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.090197e-01 | 0.041 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.119616e-01 | 0.040 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.119616e-01 | 0.040 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 9.119616e-01 | 0.040 | 0 | 0 |
| HDL remodeling | R-HSA-8964058 | 9.133682e-01 | 0.039 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 9.133682e-01 | 0.039 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 9.133682e-01 | 0.039 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 9.133682e-01 | 0.039 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.133682e-01 | 0.039 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 9.133682e-01 | 0.039 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.133682e-01 | 0.039 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 9.139443e-01 | 0.039 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.139443e-01 | 0.039 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 9.139443e-01 | 0.039 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.139443e-01 | 0.039 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 9.192793e-01 | 0.037 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.193183e-01 | 0.037 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 9.201974e-01 | 0.036 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.207326e-01 | 0.036 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 9.207326e-01 | 0.036 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 9.207326e-01 | 0.036 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.207326e-01 | 0.036 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.207326e-01 | 0.036 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 9.217689e-01 | 0.035 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.217689e-01 | 0.035 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.217689e-01 | 0.035 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.251560e-01 | 0.034 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 9.251560e-01 | 0.034 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.269348e-01 | 0.033 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.270141e-01 | 0.033 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 9.270141e-01 | 0.033 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.270141e-01 | 0.033 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.293554e-01 | 0.032 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 9.293554e-01 | 0.032 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 9.293554e-01 | 0.032 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.293554e-01 | 0.032 | 0 | 0 |
| Abacavir metabolism | R-HSA-2161541 | 9.293554e-01 | 0.032 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 9.293554e-01 | 0.032 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.293554e-01 | 0.032 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.293554e-01 | 0.032 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.299330e-01 | 0.032 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 9.328233e-01 | 0.030 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 9.328233e-01 | 0.030 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.328233e-01 | 0.030 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.328233e-01 | 0.030 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 9.362066e-01 | 0.029 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 9.362066e-01 | 0.029 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.362066e-01 | 0.029 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.362066e-01 | 0.029 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 9.362066e-01 | 0.029 | 0 | 0 |
| Androgen biosynthesis | R-HSA-193048 | 9.362066e-01 | 0.029 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.365423e-01 | 0.028 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.381927e-01 | 0.028 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 9.423938e-01 | 0.026 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.423938e-01 | 0.026 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.423938e-01 | 0.026 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.423938e-01 | 0.026 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.423938e-01 | 0.026 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.431077e-01 | 0.025 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 9.431528e-01 | 0.025 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.467753e-01 | 0.024 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.477327e-01 | 0.023 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.479812e-01 | 0.023 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 9.479812e-01 | 0.023 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 9.479812e-01 | 0.023 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.479812e-01 | 0.023 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.479812e-01 | 0.023 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.479812e-01 | 0.023 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.479812e-01 | 0.023 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.479812e-01 | 0.023 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.479812e-01 | 0.023 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.489288e-01 | 0.023 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.496550e-01 | 0.022 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.527485e-01 | 0.021 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.530269e-01 | 0.021 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 9.530269e-01 | 0.021 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.530269e-01 | 0.021 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.530269e-01 | 0.021 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.538595e-01 | 0.021 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.539232e-01 | 0.020 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.558581e-01 | 0.020 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.563392e-01 | 0.019 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.575835e-01 | 0.019 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.575835e-01 | 0.019 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.575835e-01 | 0.019 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.575835e-01 | 0.019 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.575835e-01 | 0.019 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.575835e-01 | 0.019 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.575835e-01 | 0.019 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 9.575835e-01 | 0.019 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.575835e-01 | 0.019 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.578149e-01 | 0.019 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.616984e-01 | 0.017 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 9.616984e-01 | 0.017 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.616984e-01 | 0.017 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.616984e-01 | 0.017 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.627658e-01 | 0.016 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.645502e-01 | 0.016 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.651210e-01 | 0.015 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.654142e-01 | 0.015 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.686285e-01 | 0.014 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.687698e-01 | 0.014 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.687698e-01 | 0.014 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.688973e-01 | 0.014 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.688973e-01 | 0.014 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.688973e-01 | 0.014 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.692003e-01 | 0.014 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.718000e-01 | 0.012 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 9.745363e-01 | 0.011 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.745363e-01 | 0.011 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.747104e-01 | 0.011 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.757863e-01 | 0.011 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.760281e-01 | 0.011 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.770073e-01 | 0.010 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.770073e-01 | 0.010 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 9.770073e-01 | 0.010 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.778000e-01 | 0.010 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 9.792130e-01 | 0.009 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.792386e-01 | 0.009 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.792386e-01 | 0.009 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.792386e-01 | 0.009 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.804309e-01 | 0.009 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.804956e-01 | 0.009 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.812535e-01 | 0.008 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.813521e-01 | 0.008 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.831086e-01 | 0.007 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.833439e-01 | 0.007 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.840632e-01 | 0.007 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.840831e-01 | 0.007 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.840831e-01 | 0.007 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.847159e-01 | 0.007 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 9.847159e-01 | 0.007 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.850983e-01 | 0.007 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.856674e-01 | 0.006 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.868818e-01 | 0.006 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.868818e-01 | 0.006 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.868818e-01 | 0.006 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.875392e-01 | 0.005 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.879865e-01 | 0.005 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.887489e-01 | 0.005 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.887489e-01 | 0.005 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.887489e-01 | 0.005 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.888576e-01 | 0.005 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.890236e-01 | 0.005 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.895081e-01 | 0.005 | 0 | 0 |
| tRNA processing in the mitochondrion | R-HSA-6785470 | 9.898412e-01 | 0.004 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.898412e-01 | 0.004 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.899382e-01 | 0.004 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.908275e-01 | 0.004 | 0 | 0 |
| Diseases associated with N-glycosylation of proteins | R-HSA-3781860 | 9.908275e-01 | 0.004 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.916107e-01 | 0.004 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.917181e-01 | 0.004 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.917181e-01 | 0.004 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.917181e-01 | 0.004 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 9.932484e-01 | 0.003 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 9.932484e-01 | 0.003 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 9.932484e-01 | 0.003 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.939041e-01 | 0.003 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.939041e-01 | 0.003 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.939041e-01 | 0.003 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.941139e-01 | 0.003 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.941730e-01 | 0.003 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 9.944961e-01 | 0.002 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.944961e-01 | 0.002 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.946201e-01 | 0.002 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.950307e-01 | 0.002 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.950307e-01 | 0.002 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.952363e-01 | 0.002 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.955134e-01 | 0.002 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.955134e-01 | 0.002 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.968736e-01 | 0.001 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.970188e-01 | 0.001 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.970188e-01 | 0.001 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.971454e-01 | 0.001 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.973084e-01 | 0.001 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.973603e-01 | 0.001 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.973603e-01 | 0.001 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.974645e-01 | 0.001 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.975700e-01 | 0.001 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.976148e-01 | 0.001 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.977343e-01 | 0.001 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.981464e-01 | 0.001 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.981914e-01 | 0.001 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.982118e-01 | 0.001 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.984519e-01 | 0.001 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.984953e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.986842e-01 | 0.001 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 9.988584e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.989275e-01 | 0.000 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 9.989275e-01 | 0.000 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.989275e-01 | 0.000 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.990318e-01 | 0.000 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.990318e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.991259e-01 | 0.000 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.991259e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.991347e-01 | 0.000 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.992109e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.992196e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.993456e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.993569e-01 | 0.000 | 0 | 0 |
| Latent infection - Other responses of Mtb to phagocytosis | R-HSA-1222499 | 9.994195e-01 | 0.000 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.995269e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.995269e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.995269e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.995269e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.995729e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.996519e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.996776e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.996858e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.997164e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.997164e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.997440e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.997914e-01 | 0.000 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.998465e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.998465e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.998615e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.998624e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.998824e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999372e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999603e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999652e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999734e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999802e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999822e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999842e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999853e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999869e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999951e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999953e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999956e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999962e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999972e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999976e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.999981e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999986e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 9.999992e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999992e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999996e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999996e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999996e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999997e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999997e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999997e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999999e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999999e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999999e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
