PAK1
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| O00273 | S37 | Sugiyama | DFFA DFF1 DFF45 H13 | TLKPCLLRRNysREQHGVAAsCLEDLRSKACDILAIDKSLT |
| O00429 | T78 | Sugiyama | DNM1L DLP1 DRP1 | VTRRPLILQLVHVSQEDKRKtTGEENGVEAEEWGKFLHTKN |
| O00571 | S594 | Sugiyama | DDX3X DBX DDX3 | MAyEHHyKGssRGRSKssRFsGGFGARDYRQssGAssssFs |
| O00571 | S82 | Sugiyama | DDX3X DBX DDX3 | ssKDKDAyssFGsRsDsRGKssFFsDRGsGsRGRFDDRGRs |
| O14737 | S42 | Sugiyama | PDCD5 TFAR19 | GDPGDAAQQEAKHREAEMRNsILAQVLDQsARARLsNLALV |
| O14965 | S342 | PSP | AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6 | FLVGKPPFEANTYQETYKRIsRVEFTFPDFVTEGARDLISR |
| O14965 | T288 | PSP | AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6 | GELKIADFGWsVHAPssRRttLCGTLDYLPPEMIEGRMHDE |
| O14974 | S692 | Sugiyama | PPP1R12A MBS MYPT1 | PVRDEEsEsQRKARSRQARQsRRstQGVtLtDLQEAEKtIG |
| O14974 | S695 | Sugiyama | PPP1R12A MBS MYPT1 | DEEsEsQRKARSRQARQsRRstQGVtLtDLQEAEKtIGRSR |
| O14974 | S912 | Sugiyama | PPP1R12A MBS MYPT1 | TssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDSTDF |
| O14974 | T700 | Sugiyama | PPP1R12A MBS MYPT1 | sQRKARSRQARQsRRstQGVtLtDLQEAEKtIGRSRSTRTR |
| O15143 | T21 | iPTMNet|PSP | ARPC1B ARC41 | MAYHSFLVEPISCHAWNKDRtQIAICPNNHEVHIyEKSGAK |
| O15212 | T107 | Sugiyama | PFDN6 HKE2 PFD6 | IKRYESQLRDLERQsEQQREtLAQLQQEFQRAQAAKAGAPG |
| O15372 | S290 | Sugiyama | EIF3H EIF3S3 | QQQQKHQYQQRRQQENMQRQsRGEPPLPEEDLsKLFKPPQP |
| O43159 | S309 | Sugiyama | RRP8 KIAA0409 NML hucep-1 | KKWPLQPVDRIARDLRQRPAsLVVADFGCGDCRLASSIRNP |
| O43390 | T429 | Sugiyama | HNRNPR HNRPR | AKPPDKKRKERQAARQAsRstAyEDyyyHPPPRMPPPIRGR |
| O43399 | S104 | Sugiyama | TPD52L2 | stLGELKQNLsRsWHDVQVssAyVKTSEKLGEWNEKVTQSD |
| O43423 | S100 | Sugiyama | ANP32CP PP32R1 | AEKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCE |
| O43423 | T101 | Sugiyama | ANP32CP PP32R1 | EKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCEV |
| O43488 | S40 | Sugiyama | AKR7A2 AFAR AFAR1 AKR7 | SPPPEARALAMSRPPPPRVAsVLGTMEMGRRMDAPAsAAAV |
| O43623 | S251 | PSP | SNAI2 SLUG SLUGH | HLQTHsDVKKYQCKNCsKTFsRMsLLHKHEESGCCVAH___ |
| O43707 | S423 | Sugiyama | ACTN4 | NEIRRLERLDHLAEKFRQKAsIHEAWtDGKEAMLKHRDyEt |
| O43823 | S124 | Sugiyama | AKAP8 AKAP95 | SKEGGRGGsGGGGEGIQDREssFRFQPFESYDSRPCLPEHN |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60343 | S757 | Sugiyama | TBC1D4 AS160 KIAA0603 | ASESSDGEGRKRtSstCsNEsLsVGGTSVTPRRISWRQRIF |
| O60739 | T43 | Sugiyama | EIF1B | LPAGTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAF |
| O60814 | S39 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| O60841 | S182 | Sugiyama | EIF5B IF2 KIAA0741 | DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK |
| O60841 | S183 | Sugiyama | EIF5B IF2 KIAA0741 | GsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKN |
| O75116 | S762 | Sugiyama | ROCK2 KIAA0619 | EERTLKQKVENLLLEAEKRCsLLDCDLKQSQQKINELLKQK |
| O75665 | S899 | Sugiyama | OFD1 CXorf5 | EEKIREQQVKERRQREERRQsNLQEVLERERRELEKLyQER |
| O75914 | S120 | Sugiyama | PAK3 OPHN3 | MCPGKLPEGIPEQWARLLQtsNItKLEQKKNPQAVLDVLKF |
| O75937 | S81 | Sugiyama | DNAJC8 SPF31 HSPC315 HSPC331 | VLQIDPEVTDEEIKKRFRQLsILVHPDKNQDDADRAQKAFE |
| O76021 | S314 | Sugiyama | RSL1D1 CATX11 CSIG PBK1 L12 | RNFEKQKERKKKRQQARKtAsVLsKDDVAPEsGDtTVKKPE |
| O94804 | S448 | Sugiyama | STK10 LOK | KQVAEQGGDLsPAANRsQKAsQsRPNssALEtLGGEKLANG |
| O95218 | S143 | Sugiyama | ZRANB2 ZIS ZNF265 | EyDEFGRKKKKYRGKAVGPAsILKEVEDKEsEGEEEDEDED |
| O95626 | S104 | Sugiyama | ANP32D PP32R2 | AEKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCE |
| O95626 | T105 | Sugiyama | ANP32D PP32R2 | EKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCEV |
| O95678 | S162 | Sugiyama | KRT75 K6HF KB18 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| O95831 | S100 | Sugiyama | AIFM1 AIF PDCD8 | AGAYAYKTMKEDEKRyNERIsGLGLtPEQKQKKAALsAsEG |
| O95863 | S246 | ELM|iPTMNet|PSP | SNAI1 SNAH | HLQTHsDVKKYQCQACARTFsRMsLLHKHQESGCSGCPR__ |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S237 | Sugiyama | LDHA PIG19 | DLGtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVA |
| P00491 | S176 | Sugiyama | PNP NP | GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA |
| P00558 | S174 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | T369 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV |
| P00558 | T376 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG |
| P02538 | S176 | Sugiyama | KRT6A K6A KRT6D | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT |
| P03372 | S305 | ELM|iPTMNet|PSP | ESR1 ESR NR3A1 | DMRAANLWPsPLMIKRSKKNsLALSLtADQMVSALLDAEPP |
| P04040 | S515 | Sugiyama | CAT | ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________ |
| P04040 | S517 | Sugiyama | CAT | LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________ |
| P04040 | T511 | Sugiyama | CAT | SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____ |
| P04049 | S338 | ELM|iPTMNet|PSP | RAF1 RAF | RAPVsGtQEKNKIRPRGQRDssyyWEIEASEVMLSTRIGsG |
| P04049 | S339 | ELM|iPTMNet|PSP | RAF1 RAF | APVsGtQEKNKIRPRGQRDssyyWEIEASEVMLSTRIGsGs |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04083 | S182 | Sugiyama | ANXA1 ANX1 LPC1 | RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD |
| P04259 | S176 | Sugiyama | KRT6B K6B KRTL1 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P04792 | S86 | Sugiyama | HSPB1 HSP27 HSP28 | PAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAP |
| P05362 | S43 | Sugiyama | ICAM1 | GPGNAQTSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETP |
| P05387 | S29 | Sugiyama | RPLP2 D11S2243E RPP2 | LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK |
| P05387 | Y7 | Sugiyama | RPLP2 D11S2243E RPP2 | ______________MRyVAsyLLAALGGNssPsAKDIKKIL |
| P05783 | S305 | Sugiyama | KRT18 CYK18 PIG46 | QSAEVGAAETTLTELRRtVQsLEIDLDsMRNLKAsLENsLR |
| P05783 | S93 | Sugiyama | KRT18 CYK18 PIG46 | GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR |
| P05787 | S104 | Sugiyama | KRT8 CYK8 | IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS |
| P05787 | S280 | Sugiyama | KRT8 CYK8 | IAEVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDL |
| P05787 | S330 | Sugiyama | KRT8 CYK8 | MNRNISRLQAEIEGLKGQRAsLEAAIADAEQRGELAIKDAN |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | T55 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP |
| P06899 | S39 | Sugiyama | H2BC11 H2BFR HIST1H2BJ | VTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKA |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07602 | S29 | Sugiyama | PSAP GLBA SAP1 | SLLGAALAGPVLGLKECtRGsAVWCQNVKTASDCGAVKHCL |
| P07737 | S72 | Sugiyama | PFN1 | VGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFsMDLRtKs |
| P07737 | S77 | Sugiyama | PFN1 | ssFyVNGLtLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAP |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | T317 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08238 | S206 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEDQtEyLEERRVKEVVKKHsQFIGyPItLyLEKEREKEIs |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S470 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs |
| P08238 | S482 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | T214 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EERRVKEVVKKHsQFIGyPItLyLEKEREKEIsDDEAEEEK |
| P08238 | T309 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08238 | T459 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEt |
| P08238 | Y457 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK |
| P08670 | S26 | ELM | VIM | VssssYRRMFGGPGtAsRPsssRsYVttsTRtYsLGsALRP |
| P08670 | S325 | Sugiyama | VIM | NNDALRQAKQESTEYRRQVQsLtCEVDALKGtNEsLERQMR |
| P08670 | S39 | ELM | VIM | GtAsRPsssRsYVttsTRtYsLGsALRPstsRsLyAssPGG |
| P08670 | S51 | ELM | VIM | VttsTRtYsLGsALRPstsRsLyAssPGGVyAtRssAVRLR |
| P08670 | S56 | ELM|PSP | VIM | RtYsLGsALRPstsRsLyAssPGGVyAtRssAVRLRssVPG |
| P08670 | S66 | ELM | VIM | PstsRsLyAssPGGVyAtRssAVRLRssVPGVRLLQDsVDF |
| P08670 | S73 | ELM | VIM | yAssPGGVyAtRssAVRLRssVPGVRLLQDsVDFsLADAIN |
| P08729 | S104 | Sugiyama | KRT7 SCL | LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT |
| P08758 | T8 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | _____________MAQVLRGtVtDFPGFDERADAEtLRKAM |
| P09104 | S37 | Sugiyama | ENO2 | NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09382 | T58 | Sugiyama | LGALS1 | DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF |
| P09972 | S45 | Sugiyama | ALDOC ALDC | APGKGILAADEsVGsMAKRLsQIGVENtEENRRLYRQVLFs |
| P0CG47 | S57 | Sugiyama | UBB | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P0CG48 | S57 | Sugiyama | UBC | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P10412 | S41 | Sugiyama | H1-4 H1F4 HIST1H1E | KKKARKsAGAAKRKAsGPPVsELItKAVAASKERsGVsLAA |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | S432 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMTKD |
| P11142 | T37 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P11142 | T38 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11413 | Y107 | Sugiyama | G6PD | FFKATPEEKLKLEDFFARNsyVAGQyDDAAsyQRLNsHMNA |
| P11717 | S1951 | Sugiyama | IGF2R MPRI | ADYDRDHEWGFCRHSNSYRTssIIFKCDEDEDIGRPQVFSE |
| P12035 | S211 | Sugiyama | KRT3 | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN |
| P12277 | T327 | Sugiyama | CKB CKBB | KFsEVLKRLRLQKRGtGGVDtAAVGGVFDVsNADRLGFSEV |
| P12814 | S404 | Sugiyama | ACTN1 | NEIRRLERLDHLAEKFRQKAsIHEAWtDGKEAMLRQKDyEt |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S38 | Sugiyama | EEF2 EF2 | NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD |
| P13639 | S732 | Sugiyama | EEF2 EF2 | DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP |
| P13647 | S181 | Sugiyama | KRT5 | IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P13807 | S710 | Sugiyama | GYS1 GYS | APEWPRRAsCTsSTSGSKRNsVDtAtsssLstPsEPLsPts |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P13929 | S37 | Sugiyama | ENO3 | NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14618 | T45 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI |
| P14618 | T50 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S514 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14866 | S543 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | ELGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLN |
| P15056 | S446 | ELM|iPTMNet|PSP | BRAF BRAF1 RAFB1 | RKsssssEDRNRMKtLGRRDssDDWEIPDGQITVGQRIGsG |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15311 | S536 | Sugiyama | EZR VIL2 | KRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNE |
| P15880 | S206 | Sugiyama | RPS2 RPS4 | GRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDCytsA |
| P15880 | T202 | Sugiyama | RPS2 RPS4 | CKVTGRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDC |
| P15924 | S1658 | Sugiyama | DSP | DVLDGHLREKQRTQEELRRLssEVEALRRQLLQEQESVKQA |
| P16402 | S42 | Sugiyama | H1-3 H1F3 HIST1H1D | KKAKKAGATAGKRKAsGPPVsELItKAVAASKERsGVsLAA |
| P16403 | S41 | Sugiyama | H1-2 H1F2 HIST1H1C | KKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsGVsLAA |
| P16949 | S16 | ELM|iPTMNet|PSP|Sugiyama | STMN1 C1orf215 LAP18 OP18 | _____MAssDIQVKELEKRAsGQAFELILsPRsKEsVPEFP |
| P16949 | S38 | PSP | STMN1 C1orf215 LAP18 OP18 | QAFELILsPRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAE |
| P17544 | S44 | Sugiyama | ATF7 ATFA | LAVHKHKHEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEV |
| P17600 | S605 | ELM|iPTMNet | SYN1 | QQRQGPPQKPPGPAGPTRQAsQAGPVPRTGPPTTQQPRPSG |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18583 | S90 | Sugiyama | SON C21orf50 DBP5 KIAA1019 NREBP HSPC310 HSPC312 | SGVLDTELRYKPDLKEGSRKsRCVsVQtDPtDEIPTKKSKK |
| P18583 | S94 | Sugiyama | SON C21orf50 DBP5 KIAA1019 NREBP HSPC310 HSPC312 | DTELRYKPDLKEGSRKsRCVsVQtDPtDEIPTKKSKKHKKH |
| P18615 | S135 | Sugiyama | NELFE RD RDBP | sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG |
| P18621 | S5 | Sugiyama | RPL17 | ________________MVRysLDPENPtKsCKSRGSNLRVH |
| P18669 | S118 | ELM|iPTMNet|PSP | PGAM1 PGAMA CDABP0006 | LNKAETAAKHGEAQVKIWRRsyDVPPPPMEPDHPFysNIsK |
| P18669 | S23 | ELM|iPTMNet|PSP|Sugiyama | PGAM1 PGAMA CDABP0006 | AYKLVLIRHGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQ |
| P18858 | S901 | Sugiyama | LIG1 | DKQPEQATTSAQVACLYRKQsQIQNQQGEDsGsDPEDTY__ |
| P19086 | S16 | ELM|iPTMNet|PSP | GNAZ | _____MGCRQSSEEKEAARRsRRIDRHLRSEsQRQRREIKL |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P20618 | S162 | Sugiyama | PSMB1 PSC5 | DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG |
| P20810 | S366 | Sugiyama | CAST | DKDGKPLLPEPEEKPKPRsEsELIDELsEDFDRsECKEKPS |
| P20810 | S411 | Sugiyama | CAST | KTEESKAAAPAPVSEAVCRtsMCsIQSAPPEPATLKGTVPD |
| P21333 | S2152 | ELM|iPTMNet|PSP | FLNA FLN FLN1 | VKVTGEGRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQ |
| P21333 | S2292 | PSP | FLNA FLN FLN1 | AIAVEGPsKAEIsFEDRKDGsCGVAyVVQEPGDyEVsVKFN |
| P21333 | S2370 | PSP | FLNA FLN FLN1 | PASFAVSLNGAKGAIDAKVHsPsGALEECyVtEIDQDKYAV |
| P22626 | S189 | Sugiyama | HNRNPA2B1 HNRPA2B1 | IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF |
| P23142 | T250 | Sugiyama | FBLN1 PP213 | GESCINTVGSFRCQRDssCGtGYELTEDNSCKDIDECESGI |
| P23527 | S39 | Sugiyama | H2BC17 H2BFH H2BFN HIST1H2BO | VTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGISSKA |
| P23588 | S207 | Sugiyama | EIF4B | DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR |
| P23588 | S359 | Sugiyama | EIF4B | RstPKEDDSsASTSQSTRAAsIFGGAKPVDtAAREREVEER |
| P23588 | T205 | Sugiyama | EIF4B | GRDRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYR |
| P24534 | S141 | Sugiyama | EEF1B2 EEF1B EF1B | ERLAQYESKKAKKPALVAKssILLDVKPWDDEtDMAKLEEC |
| P24844 | S20 | PSP | MYL9 MLC2 MRLC1 MYRL2 | _MssKRAKAKtTKKRPQRAtsNVFAMFDQSQIQEFKEAFNM |
| P25054 | S1389 | Sugiyama | APC DP2.5 | PKsPPEHYVQETPLMFsRCTsVSsLDSFESRSIASSVQSEP |
| P25205 | S447 | Sugiyama | MCM3 | EQGRVTIAKAGIHARLNARCsVLAAANPVyGRyDQyKTPME |
| P25398 | S107 | Sugiyama | RPS12 | EWVGLCKIDREGKPRKVVGCsCVVVKDYGKESQAKDVIEEy |
| P25705 | S76 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV |
| P25789 | T10 | Sugiyama | PSMA4 HC9 PSC9 | ___________MSRRyDsRttIFsPEGRLYQVEYAMEAIGH |
| P25789 | T9 | Sugiyama | PSMA4 HC9 PSC9 | ____________MSRRyDsRttIFsPEGRLYQVEYAMEAIG |
| P25789 | Y5 | Sugiyama | PSMA4 HC9 PSC9 | ________________MSRRyDsRttIFsPEGRLYQVEYAM |
| P26038 | S429 | Sugiyama | MSN | DQKKTQEQLALEMAELtARIsQLEMARQKKEsEAVEWQQKA |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | T24 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR |
| P26885 | S108 | Sugiyama | FKBP2 FKBP13 | GWDQGLLGMCEGEKRKLVIPsELGyGERGAPPKIPGGATLV |
| P27348 | S45 | Sugiyama | YWHAQ | CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI |
| P27348 | S63 | Sugiyama | YWHAQ | LLsVAyKNVVGGRRSAWRVIsSIEQKTDTSDKKLQLIKDYR |
| P27708 | S1859 | Sugiyama | CAD | RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P28340 | S1064 | Sugiyama | POLD1 POLD | LNALEERFSRLWTQCQRCQGsLHEDVICTSRDCPIFyMRKK |
| P29401 | S439 | Sugiyama | TKT | VSIGEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVE |
| P29401 | S443 | Sugiyama | TKT | EDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAAN |
| P29401 | S473 | Sugiyama | TKT | AtEKAVELAANTKGICFIRTsRPENAIIyNNNEDFQVGQAK |
| P29401 | T442 | Sugiyama | TKT | GEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAA |
| P29401 | T444 | Sugiyama | TKT | DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT |
| P29466 | S376 | iPTMNet | CASP1 IL1BC IL1BCE | HMQEYACSCDVEEIFRKVRFsFEQPDGRAQMPTTERVTLTR |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S60 | Sugiyama | EEF1D EF1D | ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL |
| P29692 | S86 | Sugiyama | EEF1D EF1D | GPGAssGtsGDHGELVVRIAsLEVENQsLRGVVQELQQAIs |
| P30048 | S199 | Sugiyama | PRDX3 AOP1 | SGLALRGLFIIDPNGVIKHLsVNDLPVGRSVEETLRLVKAF |
| P30085 | S47 | Sugiyama | CMPK1 CMK CMPK UCK UMK UMPK | yGytHLSAGELLRDERKNPDsQyGELIEKYIKEGKIVPVEI |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | T65 | Sugiyama | PEBP1 PBP PEBP | QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH |
| P30101 | S98 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | VPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGP |
| P31943 | S269 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH |
| P31946 | S47 | Sugiyama | YWHAB | AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P31946 | S65 | Sugiyama | YWHAB | LLsVAyKNVVGARRSsWRVIsSIEQKTERNEKKQQMGKEYR |
| P31947 | S45 | Sugiyama | SFN HME1 | FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI |
| P32119 | S112 | Sugiyama | PRDX2 NKEFB TDPX1 | KEGGLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFII |
| P32119 | T142 | Sugiyama | PRDX2 NKEFB TDPX1 | EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF |
| P33240 | S562 | Sugiyama | CSTF2 | MQVLQLTADQIAMLPPEQRQsILILKEQIQKSTGAP_____ |
| P33316 | S120 | Sugiyama | DUT | PsKRARPAEVGGMQLRFARLsEHAtAPTRGsARAAGYDLYS |
| P33778 | S39 | Sugiyama | H2BC3 H2BFF HIST1H2BB | ITKAQKKDGKKRKRsRKEsysIyVyKVLKQVHPDTGISSKA |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34931 | T39 | Sugiyama | HSPA1L | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P34931 | T40 | Sugiyama | HSPA1L | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P34932 | S76 | Sugiyama | HSPA4 APG2 HSPH2 | VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT |
| P35222 | S552 | PSP | CTNNB1 CTNNB OK/SW-cl.35 PRO2286 | AIPRLVQLLVRAHQDtQRRtsMGGtQQQFVEGVRMEEIVEG |
| P35222 | S675 | PSP | CTNNB1 CTNNB OK/SW-cl.35 PRO2286 | AAAVLFRMSEDKPQDyKKRLsVELtssLFRTEPMAWNETAD |
| P35240 | S518 | ELM|PSP | NF2 SCH | FNLIGDSLSFDFKDTDMKRLsMEIEKEKVEYMEKSKHLQEQ |
| P35908 | S191 | Sugiyama | KRT2 KRT2A KRT2E | IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| P36578 | S55 | Sugiyama | RPL4 RPL1 | DIVNFVHTNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVAR |
| P36578 | S66 | Sugiyama | RPL4 RPL1 | KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P36871 | T467 | ELM|iPTMNet|PSP | PGM1 | ALMFDRSFVGKQFSANDKVYtVEKADNFEysDPVDGsIsRN |
| P37108 | S25 | Sugiyama | SRP14 | EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37837 | S13 | Sugiyama | TALDO1 TAL TALDO TALDOR | ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA |
| P38606 | S384 | Sugiyama | ATP6V1A ATP6A1 ATP6V1A1 VPP2 | RLAEMPADSGYPAyLGARLAsFYERAGRVKCLGNPEREGSV |
| P38646 | S148 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | YDDPEVQKDIKNVPFKIVRAsNGDAWVEAHGKLYSPSQIGA |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P39023 | S13 | Sugiyama | RPL3 OK/SW-cl.32 | ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP |
| P39687 | S104 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | AEKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCE |
| P39687 | T105 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | EKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCEV |
| P40617 | S143 | PSP | ARL4A ARL4 | ENQGVPVLIVANKQDLRNSLsLSEIEKLLAMGELSSSTPWH |
| P41567 | T43 | Sugiyama | EIF1 SUI1 | LPAGTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAF |
| P43121 | S93 | Sugiyama | MCAM MUC18 | IFRVRQGQGQSEPGEYEQRLsLQDRGAtLALtQVtPQDERI |
| P43243 | S188 | Sugiyama | MATR3 KIAA0723 | EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P43490 | S35 | Sugiyama | NAMPT PBEF PBEF1 | TDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKYE |
| P46013 | S299 | Sugiyama | MKI67 | GLQGETQLLVSRKSRPKsGGsGHAVAEPAsPEQELDQNKGK |
| P46013 | S648 | Sugiyama | MKI67 | RVSISRsQHDILQMICSKRRsGAsEANLIVAKSWADVVKLG |
| P46108 | S41 | PSP | CRK | QEAVALLQGQRHGVFLVRDsstsPGDyVLSVSENSRVSHYI |
| P46459 | S207 | Sugiyama | NSF | KAENSSLNLIGKAKTKENRQsIINPDWNFEKMGIGGLDKEF |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46940 | S730 | Sugiyama | IQGAP1 KIAA0051 | PPNFVQNSMQLSREEIQsSIsGVTAAYNREQLWLANEGLIT |
| P47712 | S727 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP |
| P48668 | S176 | Sugiyama | KRT6C KRT6E | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P48728 | T397 | Sugiyama | AMT GCST | LVEVRRKQQMAVVSKMPFVPtNYYTLK______________ |
| P49023 | S258 | PSP | PXN | NQGEMssPQRVTsTQQQtRIsAssAtRELDELMAsLsDFKI |
| P49419 | S84 | Sugiyama | ALDH7A1 ATQ1 | EVIttyCPANNEPIARVRQAsVADyEEtVKKAREAWKIWAD |
| P49588 | S775 | Sugiyama | AARS1 AARS | VTGAEAQKALRKAESLKKCLsVMEAKVKAQTAPNKDVQREI |
| P49703 | S144 | PSP | ARL4D ARF4L | DNQGVPVLVLANKQDQPGALsAAEVEKRLAVRELAAATLTH |
| P49736 | S229 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | sHGHNVFKERIsDMCKENREsLVVNyEDLAAREHVLAYFLP |
| P50395 | S382 | PSP | GDI2 RABGDIB | PEKEIRPALELLEPIEQKFVsISDLLVPKDLGtEsQIFIsR |
| P50395 | S396 | Sugiyama | GDI2 RABGDIB | IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD |
| P50395 | S427 | Sugiyama | GDI2 RABGDIB | ttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED__ |
| P50395 | T248 | PSP | GDI2 RABGDIB | LyGLGELPQGFARLSAIYGGtYMLNKPIEEIIVQNGKVIGV |
| P50395 | T425 | Sugiyama | GDI2 RABGDIB | DAttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED |
| P50990 | S23 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | LHVPKAPGFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTT |
| P50991 | T50 | Sugiyama | CCT4 CCTD SRB | PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI |
| P51114 | S420 | PSP | FXR1 | GtNsELsNPsEtEsERKDELsDWsLAGEDDRDsRHQRDSRR |
| P51116 | S601 | Sugiyama | FXR2 FMR1L2 | RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ |
| P51116 | T610 | Sugiyama | FXR2 FMR1L2 | RRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLER |
| P51116 | Y614 | Sugiyama | FXR2 FMR1L2 | RGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPs |
| P51858 | S107 | Sugiyama | HDGF HMG1L2 | WEIENNPtVKASGYQSsQKKsCVEEPEPEPEAAEGDGDKKG |
| P52565 | S101 | ELM|iPTMNet|PSP | ARHGDIA GDIA1 | SAPGPLELDLtGDLEsFKKQsFVLKEGVEYRIKISFRVNRE |
| P52565 | S174 | ELM|iPTMNet|PSP | ARHGDIA GDIA1 | EEyEFLtPVEEAPKGMLARGsYsIKSRFTDDDKTDHLSWEW |
| P52565 | S176 | PSP | ARHGDIA GDIA1 | yEFLtPVEEAPKGMLARGsYsIKSRFTDDDKTDHLSWEWNL |
| P52732 | S39 | Sugiyama | KIF11 EG5 KNSL1 TRIP5 | IQVVVRCRPFNLAERKAsAHsIVECDPVRKEVSVRTGGLAD |
| P52907 | S123 | Sugiyama | CAPZA1 | KEAsDPQPEEADGGLKsWREsCDsALRAYVKDHYSNGFCTV |
| P53350 | S49 | PSP | PLK1 PLK | GAPAAAPPAKEIPEVLVDPRsRRRYVRGRFLGKGGFAKCFE |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P53396 | S656 | Sugiyama | ACLY | IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR |
| P53667 | T508 | ELM|iPTMNet|PSP | LIMK1 LIMK | EKTQPEGLRSLKKPDRKKRYtVVGNPyWMAPEMINGRSYDE |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T38 | Sugiyama | HSPA2 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P54652 | T39 | Sugiyama | HSPA2 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P54821 | T2 | Sugiyama | PRRX1 PMX1 | ___________________MtSSyGHVLERQPALGGRLDsP |
| P54821 | Y5 | Sugiyama | PRRX1 PMX1 | ________________MtSSyGHVLERQPALGGRLDsPGNL |
| P55081 | S94 | Sugiyama | MFAP1 | EEQEEDsssDPRLRRLQNRIsEDVEERLARHRKIVEPEVVG |
| P55795 | S269 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH |
| P57053 | S39 | Sugiyama | H2BC12L H2BFS H2BS1 | VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P58012 | S263 | ELM|iPTMNet | FOXL2 | AVVKGLAGPAASYGPyTRVQsMALPPGVVNSYNGLGGPPAA |
| P58876 | S39 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | T90 | Sugiyama | TPI1 TPI | VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P61081 | S175 | Sugiyama | UBE2M UBC12 | NNRRLFEQNVQRSMRGGyIGstyFERCLK____________ |
| P61353 | S39 | Sugiyama | RPL27 | SGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVTAAMGK |
| P61353 | S86 | Sugiyama | RPL27 | SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | S46 | Sugiyama | YWHAG | AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P61981 | S64 | Sugiyama | YWHAG | LLsVAyKNVVGARRSsWRVIsSIEQKtsADGNEKKIEMVRA |
| P62241 | S160 | Sugiyama | RPS8 OK/SW-cl.83 | KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S46 | Sugiyama | YWHAE | SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62277 | S12 | Sugiyama | RPS13 | _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD |
| P62277 | S14 | Sugiyama | RPS13 | _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK |
| P62633 | S121 | Sugiyama | CNBP RNF163 ZNF9 | CGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRCG |
| P62701 | T247 | Sugiyama | RPS4X CCG2 RPS4 SCAR | VIGKGNKPWIsLPRGKGIRLtIAEERDKRLAAKQSSG____ |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62805 | S48 | Sugiyama | H4C1 H4/A H4FA HIST1H4A; H4C2 H4/I H4FI HIST1H4B; H4C3 H4/G H4FG HIST1H4C; H4C4 H4/B H4FB HIST1H4D; H4C5 H4/J H4FJ HIST1H4E; H4C6 H4/C H4FC HIST1H4F; H4C8 H4/H H4FH HIST1H4H; H4C9 H4/M H4FM HIST1H4I; H4C11 H4/E H4FE HIST1H4J; H4C12 H4/D H4FD HIST1H4K; H4C13 H4/K H4FK HIST1H4L; H4C14 H4/N H4F2 H4FN HIST2H4 HIST2H4A; H4C15 H4/O H4FO HIST2H4B; H4C16 H4-16 HIST4H4 | QGItKPAIRRLARRGGVKRIsGLIyEETRGVLKVFLENVIR |
| P62807 | S39 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA |
| P62899 | S15 | Sugiyama | RPL31 | ______MAPAKKGGEKKKGRsAINEVVtREytINIHKRIHG |
| P62906 | S64 | Sugiyama | RPL10A NEDD6 | QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62937 | T157 | Sugiyama | PPIA CYPA | NIVEAMERFGsRNGKTSKKItIADCGQLE____________ |
| P62979 | S123 | Sugiyama | RPS27A UBA80 UBCEP1 | LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK |
| P62979 | S57 | Sugiyama | RPS27A UBA80 UBCEP1 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA |
| P62987 | S57 | Sugiyama | UBA52 UBCEP2 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI |
| P63104 | S45 | Sugiyama | YWHAZ | CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI |
| P63104 | S63 | Sugiyama | YWHAZ | LLsVAyKNVVGARRssWRVVssIEQKTEGAEKKQQMAREYR |
| P63146 | S142 | Sugiyama | UBE2B RAD6B UBCH1 | ANSQAAQLYQENKREYEKRVsAIVEQsWNDS__________ |
| P63167 | S88 | PSP | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | HETKHFIYFYLGQVAILLFKsG___________________ |
| P63220 | S31 | Sugiyama | RPS21 | LYVPRKCSASNRIIGAKDHAsIQMNVAEVDKVTGRFNGQFK |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P67809 | S209 | Sugiyama | YBX1 NSEP1 YB1 | RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ |
| P67809 | Y99 | Sugiyama | YBX1 NSEP1 YB1 | DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68104 | T432 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P78371 | S143 | Sugiyama | CCT2 99D8.1 CCTB | PQTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIA |
| P78545 | S207 | PSP | ELF3 ERT ESX JEN | GAPSPGSSDVSTAGTGASRSsHSsDsGGsDVDLDPTDGKLF |
| P83731 | S38 | Sugiyama | RPL24 | GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK |
| P83731 | S86 | Sugiyama | RPL24 | EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE |
| P83731 | T83 | Sugiyama | RPL24 | QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA |
| P84098 | S12 | Sugiyama | RPL19 | _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI |
| Q00059 | S160 | Sugiyama | TFAM TCF6 TCF6L2 | RKAMTKKKELTLLGKPKRPRsAYNVyVAERFQEAKGDsPQE |
| Q00587 | S350 | Sugiyama | CDC42EP1 BORG5 CEP1 MSE55 | HyPEMDARQERVEVLPQARAsWEsLDEEWRAPQAGsRtPVP |
| Q00610 | S147 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | VYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLLL |
| Q00613 | S375 | Sugiyama | HSF1 HSTF1 | TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01105 | T169 | Sugiyama | SET | NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK |
| Q01546 | S196 | Sugiyama | KRT76 KRT2B KRT2P | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE |
| Q02750 | S298 | ELM|iPTMNet|PSP | MAP2K1 MEK1 PRKMK1 | QVEGDAAEtPPRPRtPGRPLssyGMDsRPPMAIFELLDYIV |
| Q02818 | S369 | Sugiyama | NUCB1 NUC | RFEEELAAREAELNAKAQRLsQETEALGRsQGRLEAQKREL |
| Q02878 | S255 | Sugiyama | RPL6 TXREB1 | tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF |
| Q04695 | S28 | Sugiyama | KRT17 | FTSSSsIKGSSGLGGGsSRTsCRLsGGLGAGsCRLGSAGGL |
| Q04695 | S32 | Sugiyama | KRT17 | SsIKGSSGLGGGsSRTsCRLsGGLGAGsCRLGSAGGLGSTL |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q04917 | S64 | Sugiyama | YWHAH YWHA1 | LLsVAyKNVVGARRSsWRVIsSIEQKTMADGNEKKLEKVKA |
| Q05639 | T432 | Sugiyama | EEF1A2 EEF1AL STN | VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT |
| Q06210 | T263 | Sugiyama | GFPT1 GFAT GFPT | QGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDASA |
| Q06830 | T143 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF |
| Q12778 | S256 | iPTMNet | FOXO1 FKHR FOXO1A | WWMLNPEGGKSGKsPRRRAAsMDNNSKFAKSRSRAAKKKAs |
| Q12906 | S20 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | _MRPMRIFVNDDRHVMAKHssVyPTQEELEAVQNMVsHtER |
| Q12906 | S46 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | EELEAVQNMVsHtERALKAVsDWIDEQEKGssEQAEsDNMD |
| Q12965 | S1009 | Sugiyama | MYO1E MYO1C | yTsMARPPLPRQQstssDRVsQtPEsLDFLKVPDQGAAGVR |
| Q13085 | S1762 | Sugiyama | ACACA ACAC ACC1 ACCA | EDPYKGYRYLYLTPQDYKRVsALNsVHCEHVEDEGESRYKI |
| Q13136 | S239 | Sugiyama | PPFIA1 LIP1 | GVLDINHEQENtPstsGKRssDGsLsHEEDLAKVIELQEII |
| Q13136 | S242 | Sugiyama | PPFIA1 LIP1 | DINHEQENtPstsGKRssDGsLsHEEDLAKVIELQEIISKQ |
| Q13136 | S666 | Sugiyama | PPFIA1 LIP1 | IQEEKENTEQRAEEIESRVGsGsLDNLGRFRSMssIPPYPA |
| Q13136 | T572 | Sugiyama | PPFIA1 LIP1 | LRRPQKGRLAALRDEPSKVQtLNEQDWERAQQASVLANVAQ |
| Q13153 | S110 | Sugiyama | PAK1 | DAVTGEFTGMPEQWARLLQtsNITKsEQKKNPQAVLDVLEF |
| Q13153 | S115 | Sugiyama | PAK1 | EFTGMPEQWARLLQtsNITKsEQKKNPQAVLDVLEFYNsKK |
| Q13153 | S144 | iPTMNet|PSP|Sugiyama | PAK1 | VLDVLEFYNsKKTSNSQKYMsFtDKsAEDyNssNALNVKAV |
| Q13153 | S149 | iPTMNet|Sugiyama | PAK1 | EFYNsKKTSNSQKYMsFtDKsAEDyNssNALNVKAVsETPA |
| Q13153 | S155 | Sugiyama | PAK1 | KTSNSQKYMsFtDKsAEDyNssNALNVKAVsETPAVPPVsE |
| Q13153 | S156 | Sugiyama | PAK1 | TSNSQKYMsFtDKsAEDyNssNALNVKAVsETPAVPPVsED |
| Q13153 | S165 | iPTMNet | PAK1 | FtDKsAEDyNssNALNVKAVsETPAVPPVsEDEDDDDDDAt |
| Q13153 | S199 | iPTMNet|PSP | PAK1 | DDDDDAtPPPVIAPRPEHTKsVytRsVIEPLPVtPtRDVAt |
| Q13153 | S204 | iPTMNet|PSP | PAK1 | AtPPPVIAPRPEHTKsVytRsVIEPLPVtPtRDVAtsPIsP |
| Q13153 | S21 | iPTMNet | PAK1 | MsNNGLDIQDKPPAPPMRNTsTMIGAGSKDAGTLNHGSKPL |
| Q13153 | S57 | iPTMNet | PAK1 | GSKPLPPNPEEKKKKDRFYRsILPGDKTNKKKEKERPEISL |
| Q13153 | T146 | Sugiyama | PAK1 | DVLEFYNsKKTSNSQKYMsFtDKsAEDyNssNALNVKAVsE |
| Q13153 | T423 | EPSD|PSP | PAK1 | VKLTDFGFCAQITPEQSKRstMVGTPYWMAPEVVTRKAYGP |
| Q13177 | S109 | Sugiyama | PAK2 | DAVTGEFTGMPEQWARLLQtsNItKLEQKKNPQAVLDVLKF |
| Q13233 | S67 | PSP | MAP3K1 MAPKKK1 MEKK MEKK1 | AGSGGRERADWRRRQLRKVRsVELDQLPEQPLFLAASPPAS |
| Q13263 | S784 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK |
| Q13310 | S96 | Sugiyama | PABPC4 APP1 PABP4 | VIKGKPIRIMWSQRDPsLRKsGVGNVFIKNLDKSIDNKALy |
| Q13352 | S28 | PSP | ITGB3BP CENPR NRIF3 | KLDGLLEENsFDPSKITRKKsVItYsPttGtCQMsLFAsPT |
| Q13363 | S158 | PSP | CTBP1 CTBP | NLYRRAtWLHQALREGTRVQsVEQIREVASGAARIRGETLG |
| Q13418 | S246 | PSP | ILK ILK1 ILK2 | DWSTRKsRDFNEECPRLRIFsHPNVLPVLGACQSPPAPHPT |
| Q13418 | T173 | PSP | ILK ILK1 ILK2 | EKMGQNLNRIPYKDTFWKGttRTRPRNGtLNKHsGIDFKQL |
| Q13428 | S79 | Sugiyama | TCOF1 | LGRKRKAEEDAALQAKKTRVsDPIstsEssEEEEEAEAETA |
| Q13501 | S28 | Sugiyama | SQSTM1 ORCA OSIL | AYLLGKEDAAREIRRFsFCCsPEPEAEAEAAAGPGPCERLL |
| Q13561 | S83 | Sugiyama | DCTN2 DCTN50 | GTKGLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKY |
| Q13761 | T209 | PSP | RUNX3 AML2 CBFA3 PEBP2A3 | DQTKPFPDRFGDLERLRMRVtPstPsPRGsLsttsHFssQP |
| Q14151 | S818 | Sugiyama | SAFB2 KIAA0138 | QHYGDDRHGHGGPPERHGRDsRDGWGGyGsDKRLsEGRGLP |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14152 | S895 | Sugiyama | EIF3A EIF3S10 KIAA0139 | ERRLGDssLSRKDSRWGDRDsEGtWRKGPEADsEWRRGPPE |
| Q14157 | S360 | Sugiyama | UBAP2L KIAA0144 NICE4 | sMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLAAQHS |
| Q14160 | S1378 | Sugiyama | SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL | QKyFELEVRVPQAEGPPKRVsLVGADDLRKMQEEEARKLQQ |
| Q14247 | S113 | PSP | CTTN EMS1 | DRMDKsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVD |
| Q14247 | S405 | PSP | CTTN EMS1 | EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA |
| Q14247 | S418 | PSP | CTTN EMS1 | KtQtPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVs |
| Q14498 | S336 | Sugiyama | RBM39 HCC1 RNPC2 | LAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGR |
| Q14566 | S271 | Sugiyama | MCM6 | VPDVSKLSTPGARAEtNsRVsGVDGyEtEGIRGLRALGVRD |
| Q14671 | S709 | Sugiyama | PUM1 KIAA0099 PUMH1 | LGGFGTAVANSNTGSGSRRDsLtGSsDLYKRTSSSLTPIGH |
| Q14847 | S99 | Sugiyama | LASP1 MLN50 | ELQsQVRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsN |
| Q14980 | S1991 | Sugiyama | NUMA1 NMP22 NUMA | QPIQIAEGTGITTRQQRKRVsLEPHQGPGtPEsKKATSCFP |
| Q14CN4 | S138 | Sugiyama | KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 | IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN |
| Q15021 | S585 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | ILGLIFKGPAASTQEKNPREstGNMVTGQTVCKNKPNMsDP |
| Q15029 | S944 | Sugiyama | EFTUD2 KIAA0031 SNRP116 | QPAPHLAREFMIKTRRRKGLsEDVsIsKFFDDPMLLELAKQ |
| Q15029 | S950 | Sugiyama | EFTUD2 KIAA0031 SNRP116 | AREFMIKTRRRKGLsEDVsIsKFFDDPMLLELAKQDVVLNY |
| Q15185 | S85 | Sugiyama | PTGES3 P23 TEBP | KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN |
| Q15365 | T127 | PSP | PCBP1 | TQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT |
| Q15365 | T60 | PSP | PCBP1 | REEsGARINIsEGNCPERIItLTGPTNAIFKAFAMIIDKLE |
| Q15417 | S259 | Sugiyama | CNN3 | DNSTISLQMGTNKVAsQKGMsVyGLGRQVYDPKYCAAPTEP |
| Q15424 | S794 | Sugiyama | SAFB HAP HET SAFB1 | EREGQHYPERHGGPERHGRDsRDGWGGyGsDKRMsEGRGLP |
| Q15654 | S400 | Sugiyama | TRIP6 OIP1 | DATSQIHCIEDFHRKFAPRCsVCGGAIMPEPGQEETVRIVA |
| Q15746 | S1772 | PSP | MYLK MLCK MLCK1 MYLK1 | VRAIGRLssMAMISGLSGRKsstGsPtsPLNAEKLEsEEDV |
| Q15785 | S93 | Sugiyama | TOMM34 URCC3 | DCTSALALVPFSIKPLLRRAsAyEALEKYPMAYVDYKTVLQ |
| Q16778 | S39 | Sugiyama | H2BC21 H2BFQ HIST2H2BE | VTKAQKKDGKKRKRSRKEsysIyVyKVLKQVHPDTGIssKA |
| Q3SY84 | S143 | Sugiyama | KRT71 K6IRS1 KB34 KRT6IRS1 | IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q58FF7 | S185 | Sugiyama | HSP90AB3P HSP90BC | KEDQtEyLEERRVKEVVKKHsQFIGyPItLyLEKEQDKEIs |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | T193 | Sugiyama | HSP90AB3P HSP90BC | EERRVKEVVKKHsQFIGyPItLyLEKEQDKEIsDDEAEEEK |
| Q58FF8 | S258 | Sugiyama | HSP90AB2P HSP90BB | LAVRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQ |
| Q5JQF8 | S87 | Sugiyama | PABPC1L2A PABPC1L2 RBM32A; PABPC1L2B PABPC1L2 RBM32B | VIKGRPVRIMWSQRDPsLRKsGVGNVFIKNLGKTIDNKALY |
| Q5QNW6 | S39 | Sugiyama | H2BC18 HIST2H2BF | VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q5SW79 | S1306 | Sugiyama | CEP170 FAM68A KAB KIAA0470 | KEQEDYIRDWTAHREEIARIsQDLALIAREINDVAGEIDSV |
| Q5T0N5 | S488 | Sugiyama | FNBP1L C1orf39 TOCA1 | NEAWLSEVEGKTGGRGDRRHssDINHLVtQGREsPEGsytD |
| Q5T1M5 | S1162 | Sugiyama | FKBP15 KIAA0674 | EAGstVAGAALRPsHHsQRssLsGDEEDELFKGATLKALRP |
| Q5T9S5 | S336 | Sugiyama | CCDC18 | KEKLRIMAVKNSEVMAQLtEsRQSILKLESELENKDEILRD |
| Q5T9S5 | T334 | Sugiyama | CCDC18 | NGKEKLRIMAVKNSEVMAQLtEsRQSILKLESELENKDEIL |
| Q5VT52 | S1069 | Sugiyama | RPRD2 KIAA0460 HSPC099 | LTATDQQQQEEHYRIETRVsssCLDLPDSTEEKGAPIETLG |
| Q5VTE0 | T432 | Sugiyama | EEF1A1P5 EEF1AL3 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| Q5XKE5 | S155 | Sugiyama | KRT79 K6L KB38 KRT6L | IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| Q6AI08 | S399 | Sugiyama | HEATR6 ABC1 | KDGVSSsFSsssWKRVsssEsDFsDAEGGMQSKMRSYQAKV |
| Q6DN03 | S39 | Sugiyama | H2BC20P HIST2H2BC | VTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKA |
| Q6DRA6 | S39 | Sugiyama | H2BC19P HIST2H2BD | VTKAQKKDGKKRKRSRKEsysIyVyKVLKRVHPDTGIWCKA |
| Q6IBS0 | S139 | Sugiyama | TWF2 PTK9L MSTP011 | DELFGTVKDDLSFAGyQKHLssCAAPAPLtsAERELQQIRI |
| Q6IBS0 | S140 | Sugiyama | TWF2 PTK9L MSTP011 | ELFGTVKDDLSFAGyQKHLssCAAPAPLtsAERELQQIRIN |
| Q6PID6 | S19 | Sugiyama | TTC33 | __MASFGWKRKIGEKVSKVTsQQFEAEAADEKDVVDNDEGN |
| Q6UVK1 | S1857 | Sugiyama | CSPG4 MCSP | ASVPLRLTRGSRAPISRAQLsVVDPDSAPGEIEyEVQRAPH |
| Q6UVK1 | S321 | Sugiyama | CSPG4 MCSP | DQYPTHTSNRGVLSYLEPRGsLLLGGLDAEASRHLQEHRLG |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q70Z35 | S1107 | PSP | PREX2 DEPDC2 | FNVAGDEQEDSGHDTISNRDsYSDCNSNRNSIASFTSICSS |
| Q7RTS7 | S153 | Sugiyama | KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 | IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q7Z4V5 | S301 | Sugiyama | HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 | EKPLPKPRGRKPKPERPPSssSSDSDSDEVDRISEWKRRDE |
| Q7Z5L9 | S15 | Sugiyama | IRF2BP2 | ______MAAAVAVAAASRRQsCyLCDLPRMPWAMIWDFTEP |
| Q7Z794 | S177 | Sugiyama | KRT77 KRT1B | IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| Q86V48 | S957 | Sugiyama | LUZP1 | PTRIGKNVESTNSNAytQRsstDFsELEQPRSCLFEQGTRR |
| Q86V81 | S239 | Sugiyama | ALYREF ALY BEF THOC4 | tRGGARGRGRGAGRNSKQQLsAEELDAQLDAyNARMDts__ |
| Q86VQ1 | S223 | Sugiyama | GLCCI1 | QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR |
| Q86Y46 | S145 | Sugiyama | KRT73 K6IRS3 KB36 KRT6IRS3 | IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q8IWX8 | S904 | Sugiyama | CHERP DAN26 SCAF6 | KGVGVALDDPyENyRRNKsysFIARMKARDECK________ |
| Q8IYU2 | S385 | PSP | HACE1 KIAA1320 | HSLDEWLVLIATELMKNKRDstEITSILLKQKGQDQDAASI |
| Q8IZ21 | S117 | Sugiyama | PHACTR4 PRO2963 | KPSDAMLKNGHTTPIGNARsssPVQVEEEPVRLAsLRKAIP |
| Q8N257 | S39 | Sugiyama | H2BC26 H2BU1 HIST3H2BB | VTKAQKKDGKKRKRGRKEsysIyVyKVLKQVHPDTGIssKA |
| Q8N8S7 | S544 | Sugiyama | ENAH MENA | FDNRsyDsLHRPKstPLsQPsANGVQTEGLDYDRLKQDILD |
| Q8NBJ7 | S256 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG |
| Q8ND56 | S368 | Sugiyama | LSM14A C19orf13 FAM61A RAP55 RAP55A | EGNADEEDPLGPNCYYDKTKsFFDNIsCDDNRERRPtWAEE |
| Q8TCS8 | S767 | Sugiyama | PNPT1 PNPASE | LSRKVLQsPAtTVVRTLNDRssIVMGEPIsQSSSNsQ____ |
| Q8TD47 | T247 | Sugiyama | RPS4Y2 RPS4Y2P | VIGNGNKPWISLPRGKGIRLtIAEERDKRLAAKQSSG____ |
| Q8TDZ2 | S817 | PSP | MICAL1 MICAL NICAL | DPSQPTRRQIRLSsPERQRLssLNLTPDPEMEPPPKPPRSC |
| Q8TDZ2 | S960 | PSP | MICAL1 MICAL NICAL | AALRELEAEGVKLELALRRQsSSPEQQKKLWVGQLLQLVDK |
| Q8WZA9 | S44 | Sugiyama | IRGQ IRGQ1 FKSG27 | IAALCDKDVEtLEAPEGRPDsGVPSLRAAGPGLFLGELSCP |
| Q92934 | S118 | iPTMNet|PSP | BAD BBC6 BCL2L8 | RsAPPNLWAAQRYGRELRRMsDEFVDsFKKGLPRPKsAGtA |
| Q92934 | S134 | iPTMNet|PSP | BAD BBC6 BCL2L8 | LRRMsDEFVDsFKKGLPRPKsAGtATQMRQSSSWTRVFQsW |
| Q92934 | S74 | PSP | BAD BBC6 BCL2L8 | QPTSSSHHGGAGAVEIRsRHssyPAGtEDDEGMGEEPsPFR |
| Q92934 | S75 | PSP | BAD BBC6 BCL2L8 | PTSSSHHGGAGAVEIRsRHssyPAGtEDDEGMGEEPsPFRG |
| Q92934 | S99 | ELM|iPTMNet|PSP | BAD BBC6 BCL2L8 | GtEDDEGMGEEPsPFRGRsRsAPPNLWAAQRYGRELRRMsD |
| Q92945 | S333 | Sugiyama | KHSRP FUBP2 | DRNEyGsRIGGGIDVPVPRHsVGVVIGRSGEMIKKIQNDAG |
| Q92974 | S886 | PSP | ARHGEF2 KIAA0651 LFP40 | TEPLPAEAPWARRPVDPRRRsLPAGDALyLsFNPPQPSRGT |
| Q93079 | S39 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q969S3 | S38 | Sugiyama | ZNF622 ZPR9 | MQRAHYKTDWHRYNLRRKVAsMAPVTAEGFQERVRAQRAVA |
| Q96CT7 | S122 | Sugiyama | CCDC124 | DtLRRDHQLREAPDTAEKAKsHLEVPLEENVNRRVLEEGsV |
| Q96D15 | S117 | Sugiyama | RCN3 UNQ239/PRO272 | VsLAELRAWIAHTQQRHIRDsVsAAWDtyDtDRDGRVGWEE |
| Q96D46 | S462 | Sugiyama | NMD3 CGI-07 | FLEDLEEDEAIRKNVNIyRDsAIPVEsDtDDEGAPRISLAE |
| Q96G46 | S236 | Sugiyama | DUS3L | QQLRKREVRFERAEQALRRFsQGPtPAAAVPEGTAAEGAPR |
| Q96HC4 | S85 | Sugiyama | PDLIM5 ENH L9 | EAQNKIKGCTGsLNMtLQRAsAAPKPEPVPVQKGEPKEVVK |
| Q96IZ0 | S242 | Sugiyama | PAWR PAR4 | VSGRyKsttsVsEEDVsSRYsRTDRSGFPRYNRDANVsGtL |
| Q96JP5 | S177 | Sugiyama | ZFP91 ZNF757 FKSG11 | TSVSRHRDTENTRSSRSKTGsLQLICKSEPNTDQLDYDVGE |
| Q96L14 | S32 | Sugiyama | CEP170P1 CEP170L KIAA0470L | KEQEDYIRDWTAHREEIARIsQDLALIAREINDVAGEIDSV |
| Q96P20 | S163 | PSP | NLRP3 C1orf7 CIAS1 NALP3 PYPAF1 | YVRSRFQCIEDRNARLGEsVsLNKRYTRLRLIKEHRSQQER |
| Q96P20 | S198 | PSP | NLRP3 C1orf7 CIAS1 NALP3 PYPAF1 | RSQQEREQELLAIGKTKTCEsPVSPIKMELLFDPDDEHSEP |
| Q96P20 | T659 | PSP | NLRP3 C1orf7 CIAS1 NALP3 PYPAF1 | EEDFVQRAMDYFPKIEINLStRMDHMVSSFCIENCHRVESL |
| Q96PZ0 | S135 | Sugiyama | PUS7 KIAA1897 | GItKFVSSHQGFSGILKERysDFVVHEIGKDGRISHLNDLs |
| Q96RS6 | S373 | Sugiyama | NUDCD1 CML66 | EGLTWPELVIGDKQGELIRDsAQCAAIAERLMHLtsEELNP |
| Q96RU3 | S497 | Sugiyama | FNBP1 FBP17 KIAA0554 | AWLAEVEGRLPARSEQARRQsGLyDSQNPPTVNNCAQDREs |
| Q96T58 | S1268 | Sugiyama | SPEN KIAA0929 MINT SHARP | SRQISEDsERtGGsPsVRHGsFHEDEDPIGsPRLLSVKGsP |
| Q96T58 | S3486 | PSP | SPEN KIAA0929 MINT SHARP | stPPGLVLPHTEFQPAPKQDssPHLTSQRPVDMVQLLKKYP |
| Q96T58 | T3568 | PSP | SPEN KIAA0929 MINT SHARP | RIAQRMRLEATQLEGVARRMtVETDYCLLLALPCGRDQEDV |
| Q99426 | S128 | PSP | TBCB CG22 CKAP1 | tIsQEAyDQRQDtVRSFLKRsKLGRyNEEERAQQEAEAAQR |
| Q99426 | S65 | PSP | TBCB CG22 CKAP1 | VGSPASCMELELYGVDDKFYsKLDQEDALLGsYPVDDGCRI |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q99661 | S111 | PSP | KIF2C KNSL6 | QKRRsVNSKIPAPKEsLRsRsTRMstVSELRITAQENDMEV |
| Q99661 | S192 | PSP | KIF2C KNSL6 | QVHsIRGsssANPVNsVRRKsCLVKEVEKMKNKREEKKAQN |
| Q99832 | S59 | Sugiyama | CCT7 CCTH NIP7-1 | TLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTL |
| Q99877 | S39 | Sugiyama | H2BC15 H2BFD HIST1H2BN | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99879 | S39 | Sugiyama | H2BC14 H2BFE HIST1H2BM | INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99880 | S39 | Sugiyama | H2BC13 H2BFC HIST1H2BL | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q9BQK8 | S262 | Sugiyama | LPIN3 LIPN3L | SHMQWAWGRLPKVARAERPEsSVVLEGRAGATSPPRGGPST |
| Q9BWG6 | S199 | Sugiyama | SCNM1 | PAPMsPtRRRALDHyLTLRSsGWIPDGRGRWVKDENVEFDs |
| Q9BY44 | S524 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | DKsPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKL |
| Q9BY44 | S526 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | sPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKKKLKA |
| Q9BY44 | T522 | Sugiyama | EIF2A CDA02 MSTP004 MSTP089 | RsDKsPDLAPtPAPQstPRNtVsQsIsGDPEIDKKIKNLKK |
| Q9BZI7 | S166 | Sugiyama | UPF3B RENT3B UPF3X | KRDTKVGtIDDDPEyRKFLEsyAtDNEKMTstPEtLLEEIE |
| Q9C0C2 | S429 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | EEEAKGDAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAA |
| Q9C0C2 | S872 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | QGtyssRDAELQDQEFGKRDsLGtyssRDVsLGDWEFGKRD |
| Q9C0C2 | S893 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LGtyssRDVsLGDWEFGKRDsLGAyAsQDANEQGQDLGKRD |
| Q9C0C2 | S983 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | sGGsSRtLDAQDRsFGtRPLssGFsPEEAQQQDEEFEKKIP |
| Q9GZT3 | S15 | Sugiyama | SLIRP C14orf156 DC23 DC50 PD04872 | ______MAASAARGAAALRRsINQPVAFVRRIPWTAASSQL |
| Q9H0B6 | S428 | Sugiyama | KLC2 | NKPIWMHAEEREESKDKRRDsAPyGEyGsWYKACKVDsPtV |
| Q9H0D6 | S678 | Sugiyama | XRN2 | LRAALEEVyPDLTPEEtRRNsLGGDVLFVGKHHPLHDFILE |
| Q9H0H5 | T251 | Sugiyama | RACGAP1 KIAA1478 MGCRACGAP | EAVSTIETVPYWtRSRRKtGtLQPWNsDstLNSRQLEPRTE |
| Q9H0L4 | S601 | Sugiyama | CSTF2T KIAA0689 | MQVLQLTADQIAMLPPEQRQsILILKEQIQKSTGAS_____ |
| Q9H1Y0 | T101 | PSP | ATG5 APG5L ASP | YPIGLLFDLLASSSALPWNItVHFKSFPEKDLLHCPSKDAI |
| Q9H2G2 | S340 | Sugiyama | SLK KIAA0204 STK2 | EEDEEEEtENsLPIPAsKRAssDLsIAssEEDKLsQNACIL |
| Q9H4I2 | S658 | Sugiyama | ZHX3 KIAA0395 TIX1 | LDEELDRLRSEtKMTRREIDsWFSERRKKVNAEETKKAEEN |
| Q9HA77 | T546 | Sugiyama | CARS2 OK/SW-cl.10 | CDTLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG__ |
| Q9NPD3 | S240 | Sugiyama | EXOSC4 RRP41 SKI6 | AARDVHTLLDRVVRQHVREAsILLGD_______________ |
| Q9NPI1 | S336 | Sugiyama | BRD7 BP75 CELTIX1 | EQLDRIVKESGGKLTRRLVNsQCEFERRKPDGTTTLGLLHP |
| Q9NQX3 | T276 | Sugiyama | GPHN GPH KIAA1385 | LPRDTAsLsttPsEsPRAQAtsRLstAsCPtPKVQSRCSsK |
| Q9NQZ2 | S462 | Sugiyama | UTP3 CRLZ1 SAS10 | RAKIRRRGQVREVRKEEQRYsGELsGIRAGVKKSIKLK___ |
| Q9NSB2 | S178 | Sugiyama | KRT84 KRTHB4 | AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS |
| Q9NYF8 | S320 | Sugiyama | BCLAF1 BTF KIAA0164 | sPAKtIAPQNAPRDEsRGRssFyPDGGDQETAKtGKFLKRF |
| Q9NYV4 | S1053 | Sugiyama | CDK12 CRK7 CRKRS KIAA0904 | LPHWQDCHELWSKKRRRQRQsGVVVEEPPPSKTSRKETtsG |
| Q9NZB2 | S990 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | FPLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKN |
| Q9NZL9 | S9 | Sugiyama | MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 | ____________MVGREKELsIHFVPGsCRLVEEEVNIPNR |
| Q9P265 | S258 | Sugiyama | DIP2B KIAA1463 | ANIDLPPSGIVKGMHKGsNRssLMDTADGVPVSSRVSTKIQ |
| Q9P287 | S12 | Sugiyama | BCCIP TOK1 | _________MASRSKRRAVEsGVPQPPDPPVQRDEEEEKEV |
| Q9UHR5 | S163 | Sugiyama | SAP30BP HCNGP HTRG HTRP | IKEGMDMNyIIQRKKEFRNPsIyEKLIQFCAIDELGTNYPK |
| Q9UHR5 | Y165 | Sugiyama | SAP30BP HCNGP HTRG HTRP | EGMDMNyIIQRKKEFRNPsIyEKLIQFCAIDELGTNYPKDM |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UIQ6 | S51 | Sugiyama | LNPEP OTASE | AKEPCLHPLEPDEVEyEPRGsRLLVRGLGEHEMEEDEEDyE |
| Q9ULD2 | S1259 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | LCsPKRsPtssAIPLQsPRNsGsFPsPsIsPR_________ |
| Q9ULX6 | T267 | Sugiyama | AKAP8L NAKAP NAKAP95 HRIHFB2018 | RFGFGFGNGMKQMRRTWKTWtTADFRTKKKKRKQGGsPDEP |
| Q9UNZ2 | S74 | Sugiyama | NSFL1C UBXN2C | SQATPssVsRGTAPSDNRVtsFRDLIHDQDEDEEEEEGQRF |
| Q9UNZ2 | T73 | Sugiyama | NSFL1C UBXN2C | ISQATPssVsRGTAPSDNRVtsFRDLIHDQDEDEEEEEGQR |
| Q9UQ35 | S2453 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | QAPsQsLLPPAQDQPRsPVPsAFsDQsRCLIAQTTPVAGSQ |
| Q9UQ80 | T261 | PSP | PA2G4 EBP1 | GQRTTIYKRDPSKQYGLKMKtSRAFFsEVERRFDAMPFtLR |
| Q9Y2B0 | S115 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF |
| Q9Y2B0 | S63 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2X7 | S508 | PSP | GIT1 | AEHtPMAPGGstHRRDRQAFsMyEPGsALKPFGGPPGDELT |
| Q9Y2X7 | S700 | PSP | GIT1 | LAVTEMASLFPKRPALEPVRsSLRLLNASAYRLQSECRKTV |
| Q9Y3U8 | S91 | Sugiyama | RPL36 | KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______ |
| Q9Y5J9 | S57 | Sugiyama | TIMM8B DDP2 DDPL TIM8B | WDKCVEKPGNRLDsRTENCLsSCVDRFIDTTLAItSRFAQI |
| Q9Y608 | S18 | Sugiyama | LRRFIP2 | ___MGTPASGRKRTPVKDRFsAEDEALsNIAREAEARLAAK |
| Q9Y608 | S332 | Sugiyama | LRRFIP2 | sAsAttPLsGNssRRGsGDtssLIDPDtsLSELRDIYDLKD |
| Q9Y608 | T331 | Sugiyama | LRRFIP2 | NsAsAttPLsGNssRRGsGDtssLIDPDtsLSELRDIYDLK |
| Q9Y6A5 | Y403 | Sugiyama | TACC3 ERIC1 | EDDGRSGAGEDPPMPAsRGsyHLDWDKMDDPNFIPFGGDTK |
| Q9Y6X8 | S575 | Sugiyama | ZHX2 AFR1 KIAA0854 RAF | TQAELDRLRVETKLSRREIDsWFSERRKLRDSMEQAVLDSM |
| Q9Y6X9 | S739 | PSP | MORC2 KIAA0852 ZCWCC1 | VVKKtEsPIKLsPAtPsRKRsVAVsDEEEVEEEAERRKERC |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.004621e-08 | 7.998 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 2.122347e-08 | 7.673 | 1 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.709127e-08 | 7.567 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.635585e-07 | 6.786 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 2.178015e-07 | 6.662 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 6.978848e-07 | 6.156 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.018681e-06 | 5.992 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.279089e-06 | 5.893 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 2.379555e-06 | 5.624 | 1 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 2.607908e-06 | 5.584 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 3.041613e-06 | 5.517 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 3.615303e-06 | 5.442 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 3.924486e-06 | 5.406 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 3.834216e-06 | 5.416 | 1 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 4.049329e-06 | 5.393 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 3.408125e-06 | 5.467 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 8.030726e-06 | 5.095 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 9.242055e-06 | 5.034 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.038730e-05 | 4.983 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.288556e-05 | 4.890 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.470453e-05 | 4.833 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.543213e-05 | 4.812 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.722031e-05 | 4.764 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.818852e-05 | 4.740 | 1 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.967035e-05 | 4.706 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.961740e-05 | 4.707 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 2.119021e-05 | 4.674 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 2.368972e-05 | 4.625 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 2.838190e-05 | 4.547 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 3.034905e-05 | 4.518 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 3.003555e-05 | 4.522 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 4.349159e-05 | 4.362 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 4.722485e-05 | 4.326 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 5.282436e-05 | 4.277 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 5.282436e-05 | 4.277 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 6.017168e-05 | 4.221 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 6.164304e-05 | 4.210 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 6.914615e-05 | 4.160 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 7.231837e-05 | 4.141 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 7.304759e-05 | 4.136 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 7.858489e-05 | 4.105 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 8.018290e-05 | 4.096 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 7.892187e-05 | 4.103 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 8.828495e-05 | 4.054 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 1.051145e-04 | 3.978 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.058762e-04 | 3.975 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.077439e-04 | 3.968 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.141790e-04 | 3.942 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.204948e-04 | 3.919 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.319244e-04 | 3.880 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.416871e-04 | 3.849 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 1.452343e-04 | 3.838 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 1.600405e-04 | 3.796 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.600405e-04 | 3.796 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.966321e-04 | 3.706 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 1.964511e-04 | 3.707 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 2.207031e-04 | 3.656 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 2.353922e-04 | 3.628 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.471238e-04 | 3.607 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.527433e-04 | 3.597 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 2.600291e-04 | 3.585 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 2.800730e-04 | 3.553 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 3.053229e-04 | 3.515 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 3.584136e-04 | 3.446 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.511170e-04 | 3.455 | 0 | 0 |
| M Phase | R-HSA-68886 | 3.485967e-04 | 3.458 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 3.531370e-04 | 3.452 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 4.064531e-04 | 3.391 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 4.213238e-04 | 3.375 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 4.344504e-04 | 3.362 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 5.184026e-04 | 3.285 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 5.277571e-04 | 3.278 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 5.775984e-04 | 3.238 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 5.736196e-04 | 3.241 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 6.384099e-04 | 3.195 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 7.853823e-04 | 3.105 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 7.681510e-04 | 3.115 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 8.161843e-04 | 3.088 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 8.379140e-04 | 3.077 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 8.483318e-04 | 3.071 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 8.874950e-04 | 3.052 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 9.053111e-04 | 3.043 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 9.554379e-04 | 3.020 | 1 | 1 |
| HDMs demethylate histones | R-HSA-3214842 | 9.986664e-04 | 3.001 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 9.986664e-04 | 3.001 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 9.761865e-04 | 3.010 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.190072e-03 | 2.924 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.204736e-03 | 2.919 | 1 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.229543e-03 | 2.910 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.190072e-03 | 2.924 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.190072e-03 | 2.924 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.389143e-03 | 2.857 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 1.430448e-03 | 2.845 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 1.446894e-03 | 2.840 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.476763e-03 | 2.831 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 1.675029e-03 | 2.776 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.703964e-03 | 2.769 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 1.750823e-03 | 2.757 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.990500e-03 | 2.701 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.027311e-03 | 2.693 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 2.076056e-03 | 2.683 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 2.104885e-03 | 2.677 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 2.306925e-03 | 2.637 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.404857e-03 | 2.619 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.404857e-03 | 2.619 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 2.453085e-03 | 2.610 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 2.453085e-03 | 2.610 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 2.522407e-03 | 2.598 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 2.580501e-03 | 2.588 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 2.783193e-03 | 2.555 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 2.741671e-03 | 2.562 | 1 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 2.709451e-03 | 2.567 | 0 | 0 |
| Depurination | R-HSA-73927 | 2.988120e-03 | 2.525 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 3.257443e-03 | 2.487 | 1 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 3.458471e-03 | 2.461 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 3.585199e-03 | 2.445 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 3.640659e-03 | 2.439 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 3.640659e-03 | 2.439 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 4.270904e-03 | 2.369 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 3.986746e-03 | 2.399 | 1 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 4.159445e-03 | 2.381 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 4.038698e-03 | 2.394 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 4.299685e-03 | 2.367 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 4.380584e-03 | 2.358 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 4.384078e-03 | 2.358 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 5.106502e-03 | 2.292 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 5.106502e-03 | 2.292 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 5.155724e-03 | 2.288 | 1 | 0 |
| RET signaling | R-HSA-8853659 | 5.196811e-03 | 2.284 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 5.297074e-03 | 2.276 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 5.780691e-03 | 2.238 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 5.690979e-03 | 2.245 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 5.793682e-03 | 2.237 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 6.010705e-03 | 2.221 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 6.010705e-03 | 2.221 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 6.010705e-03 | 2.221 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 6.010705e-03 | 2.221 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 6.164314e-03 | 2.210 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 6.237952e-03 | 2.205 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 6.748246e-03 | 2.171 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 7.103736e-03 | 2.149 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 7.373353e-03 | 2.132 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 8.449306e-03 | 2.073 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 8.449306e-03 | 2.073 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 8.449306e-03 | 2.073 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 8.449306e-03 | 2.073 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 7.922406e-03 | 2.101 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 8.456808e-03 | 2.073 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 8.963814e-03 | 2.048 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.014301e-03 | 2.045 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 9.336955e-03 | 2.030 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 9.667300e-03 | 2.015 | 0 | 0 |
| Kinesins | R-HSA-983189 | 9.710899e-03 | 2.013 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.718329e-03 | 2.012 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.079367e-02 | 1.967 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.192327e-02 | 1.924 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 1.271642e-02 | 1.896 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 1.210823e-02 | 1.917 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 1.210823e-02 | 1.917 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.267767e-02 | 1.897 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 1.210823e-02 | 1.917 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.216036e-02 | 1.915 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.414755e-02 | 1.849 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 1.426697e-02 | 1.846 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 1.426697e-02 | 1.846 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.482622e-02 | 1.829 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.491797e-02 | 1.826 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 1.500102e-02 | 1.824 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.534895e-02 | 1.814 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 1.570909e-02 | 1.804 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.570909e-02 | 1.804 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.699686e-02 | 1.770 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 1.748534e-02 | 1.757 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.809613e-02 | 1.742 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.891427e-02 | 1.723 | 1 | 1 |
| RAF activation | R-HSA-5673000 | 2.119271e-02 | 1.674 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.009879e-02 | 1.697 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 2.009879e-02 | 1.697 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 2.099400e-02 | 1.678 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.940102e-02 | 1.712 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 2.182473e-02 | 1.661 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 2.182473e-02 | 1.661 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 2.182473e-02 | 1.661 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 2.186867e-02 | 1.660 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 2.211259e-02 | 1.655 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 2.298554e-02 | 1.639 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 2.322864e-02 | 1.634 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 2.338209e-02 | 1.631 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.476664e-02 | 1.606 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.476664e-02 | 1.606 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.870546e-02 | 1.542 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.870546e-02 | 1.542 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.870546e-02 | 1.542 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.870546e-02 | 1.542 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.870546e-02 | 1.542 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.764352e-02 | 1.558 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.930678e-02 | 1.533 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 2.930678e-02 | 1.533 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.813031e-02 | 1.551 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 2.665298e-02 | 1.574 | 1 | 1 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 2.852604e-02 | 1.545 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 2.689265e-02 | 1.570 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 2.741840e-02 | 1.562 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 3.042375e-02 | 1.517 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.042375e-02 | 1.517 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.045834e-02 | 1.516 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 3.111039e-02 | 1.507 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 3.291959e-02 | 1.483 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 3.313331e-02 | 1.480 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 3.332450e-02 | 1.477 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 3.358841e-02 | 1.474 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 3.358841e-02 | 1.474 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 3.387954e-02 | 1.470 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 3.417602e-02 | 1.466 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 3.506158e-02 | 1.455 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 3.515363e-02 | 1.454 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 3.515363e-02 | 1.454 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 3.585332e-02 | 1.445 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 3.585332e-02 | 1.445 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 3.595201e-02 | 1.444 | 1 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 3.686334e-02 | 1.433 | 1 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 4.149497e-02 | 1.382 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 4.269263e-02 | 1.370 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.068863e-02 | 1.391 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 3.739871e-02 | 1.427 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 4.068863e-02 | 1.391 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 4.303354e-02 | 1.366 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 4.364040e-02 | 1.360 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 4.364040e-02 | 1.360 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 4.375777e-02 | 1.359 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 4.418789e-02 | 1.355 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 4.419517e-02 | 1.355 | 1 | 1 |
| MTF1 activates gene expression | R-HSA-5660489 | 4.505912e-02 | 1.346 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 4.505912e-02 | 1.346 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 4.567956e-02 | 1.340 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.567956e-02 | 1.340 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 4.638956e-02 | 1.334 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.655765e-02 | 1.332 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 4.659817e-02 | 1.332 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 4.803788e-02 | 1.318 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 4.803788e-02 | 1.318 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 4.854154e-02 | 1.314 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 4.894322e-02 | 1.310 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 4.894322e-02 | 1.310 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 4.915251e-02 | 1.308 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 4.980941e-02 | 1.303 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 4.980941e-02 | 1.303 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 5.934935e-02 | 1.227 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 5.934935e-02 | 1.227 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 6.008889e-02 | 1.221 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 5.436083e-02 | 1.265 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 5.389854e-02 | 1.268 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 5.974647e-02 | 1.224 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 5.253104e-02 | 1.280 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 5.587366e-02 | 1.253 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 5.934935e-02 | 1.227 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 5.974647e-02 | 1.224 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 5.244658e-02 | 1.280 | 1 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 5.739126e-02 | 1.241 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 6.022417e-02 | 1.220 | 1 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 5.787208e-02 | 1.238 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 6.100057e-02 | 1.215 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 6.108133e-02 | 1.214 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 6.108133e-02 | 1.214 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 6.232980e-02 | 1.205 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 6.298912e-02 | 1.201 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 6.517201e-02 | 1.186 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 6.517201e-02 | 1.186 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 6.517201e-02 | 1.186 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 6.517201e-02 | 1.186 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 6.517201e-02 | 1.186 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 6.517201e-02 | 1.186 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 6.545563e-02 | 1.184 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 6.645257e-02 | 1.177 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 6.668439e-02 | 1.176 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 6.715714e-02 | 1.173 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 6.715714e-02 | 1.173 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 6.830900e-02 | 1.166 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 6.868307e-02 | 1.163 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 7.428127e-02 | 1.129 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 7.428127e-02 | 1.129 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 7.428127e-02 | 1.129 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 7.428127e-02 | 1.129 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 7.458963e-02 | 1.127 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 7.458963e-02 | 1.127 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 7.154009e-02 | 1.145 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 7.154009e-02 | 1.145 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 7.411015e-02 | 1.130 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 7.398187e-02 | 1.131 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 7.160530e-02 | 1.145 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 8.027604e-02 | 1.095 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 7.542550e-02 | 1.122 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 7.787179e-02 | 1.109 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 7.737137e-02 | 1.111 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 8.401804e-02 | 1.076 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 7.458963e-02 | 1.127 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 8.401804e-02 | 1.076 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 7.458963e-02 | 1.127 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 7.411015e-02 | 1.130 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 7.564863e-02 | 1.121 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 8.083503e-02 | 1.092 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 7.411015e-02 | 1.130 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 7.458963e-02 | 1.127 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 8.027604e-02 | 1.095 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 7.678199e-02 | 1.115 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 7.357173e-02 | 1.133 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 8.105026e-02 | 1.091 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 8.218647e-02 | 1.085 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 7.785360e-02 | 1.109 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 7.428127e-02 | 1.129 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 8.414220e-02 | 1.075 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 8.414220e-02 | 1.075 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 8.414985e-02 | 1.075 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 8.414985e-02 | 1.075 | 1 | 1 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 8.414985e-02 | 1.075 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 8.867318e-02 | 1.052 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 8.867318e-02 | 1.052 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 8.867318e-02 | 1.052 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 8.867318e-02 | 1.052 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 8.968141e-02 | 1.047 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 8.968141e-02 | 1.047 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 8.968141e-02 | 1.047 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 9.231348e-02 | 1.035 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 9.270323e-02 | 1.033 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 9.277583e-02 | 1.033 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 9.301859e-02 | 1.031 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 9.343098e-02 | 1.030 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 9.343098e-02 | 1.030 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 9.344707e-02 | 1.029 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 9.704918e-02 | 1.013 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 9.704918e-02 | 1.013 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 9.784400e-02 | 1.009 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 9.790872e-02 | 1.009 | 0 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 1.224320e-01 | 0.912 | 0 | 0 |
| Drug resistance of PDGFR mutants | R-HSA-9674415 | 1.224320e-01 | 0.912 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 1.224320e-01 | 0.912 | 0 | 0 |
| PDGFR mutants bind TKIs | R-HSA-9674428 | 1.224320e-01 | 0.912 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.224320e-01 | 0.912 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 1.224320e-01 | 0.912 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.224320e-01 | 0.912 | 0 | 0 |
| Regorafenib-resistant PDGFR mutants | R-HSA-9674403 | 1.224320e-01 | 0.912 | 0 | 0 |
| Sorafenib-resistant PDGFR mutants | R-HSA-9674404 | 1.224320e-01 | 0.912 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 1.224320e-01 | 0.912 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 1.224320e-01 | 0.912 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 1.224320e-01 | 0.912 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 1.224320e-01 | 0.912 | 0 | 0 |
| Imatinib-resistant PDGFR mutants | R-HSA-9674396 | 1.224320e-01 | 0.912 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 1.224320e-01 | 0.912 | 0 | 0 |
| Sunitinib-resistant PDGFR mutants | R-HSA-9674401 | 1.224320e-01 | 0.912 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 1.224320e-01 | 0.912 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.224320e-01 | 0.912 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.062244e-01 | 0.974 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.062244e-01 | 0.974 | 1 | 1 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 1.062244e-01 | 0.974 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.062244e-01 | 0.974 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.062244e-01 | 0.974 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 1.062244e-01 | 0.974 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 1.127825e-01 | 0.948 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 1.127825e-01 | 0.948 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 1.127825e-01 | 0.948 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 1.127825e-01 | 0.948 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 1.127825e-01 | 0.948 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.155878e-01 | 0.937 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.165215e-01 | 0.934 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 1.013685e-01 | 0.994 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.068314e-01 | 0.971 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.152495e-01 | 0.938 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.152495e-01 | 0.938 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.152495e-01 | 0.938 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.152495e-01 | 0.938 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 1.146952e-01 | 0.940 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.206019e-01 | 0.919 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.041032e-01 | 0.983 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 9.853271e-02 | 1.006 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.079982e-01 | 0.967 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 1.081350e-01 | 0.966 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.152495e-01 | 0.938 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 1.038691e-01 | 0.984 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 1.004942e-01 | 0.998 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.155878e-01 | 0.937 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 9.913494e-02 | 1.004 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.091035e-01 | 0.962 | 1 | 1 |
| Formation of the nephric duct | R-HSA-9830364 | 1.155878e-01 | 0.937 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.068314e-01 | 0.971 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 1.000372e-01 | 1.000 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.068314e-01 | 0.971 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.121586e-01 | 0.950 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.248576e-01 | 0.904 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 1.287281e-01 | 0.890 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.296360e-01 | 0.887 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.299518e-01 | 0.886 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.299518e-01 | 0.886 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.334627e-01 | 0.875 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.339708e-01 | 0.873 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.339708e-01 | 0.873 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.348554e-01 | 0.870 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 1.354608e-01 | 0.868 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.354608e-01 | 0.868 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.354608e-01 | 0.868 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 1.354608e-01 | 0.868 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 1.365374e-01 | 0.865 | 1 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 1.396195e-01 | 0.855 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 1.396195e-01 | 0.855 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.853038e-01 | 0.732 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.853038e-01 | 0.732 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 1.853038e-01 | 0.732 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 1.853038e-01 | 0.732 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.853038e-01 | 0.732 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 1.853038e-01 | 0.732 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 1.442142e-01 | 0.841 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 1.442142e-01 | 0.841 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.442142e-01 | 0.841 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.442142e-01 | 0.841 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 1.753590e-01 | 0.756 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 1.753590e-01 | 0.756 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 1.753590e-01 | 0.756 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.753590e-01 | 0.756 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.593010e-01 | 0.798 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.593010e-01 | 0.798 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.593010e-01 | 0.798 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.593010e-01 | 0.798 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.593010e-01 | 0.798 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.593010e-01 | 0.798 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.845417e-01 | 0.734 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.845417e-01 | 0.734 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 1.451596e-01 | 0.838 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 1.451596e-01 | 0.838 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.451596e-01 | 0.838 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.451596e-01 | 0.838 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.611694e-01 | 0.793 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.611694e-01 | 0.793 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.430432e-01 | 0.845 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 1.430432e-01 | 0.845 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.430432e-01 | 0.845 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 1.575249e-01 | 0.803 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.575249e-01 | 0.803 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 1.779334e-01 | 0.750 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 1.532377e-01 | 0.815 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 1.670461e-01 | 0.777 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 1.670461e-01 | 0.777 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 1.670461e-01 | 0.777 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.444571e-01 | 0.840 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.444571e-01 | 0.840 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 1.719473e-01 | 0.765 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 1.433612e-01 | 0.844 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.444571e-01 | 0.840 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 1.852434e-01 | 0.732 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 1.630550e-01 | 0.788 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 1.726668e-01 | 0.763 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.499513e-01 | 0.824 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.853038e-01 | 0.732 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 1.753590e-01 | 0.756 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 1.852434e-01 | 0.732 | 0 | 0 |
| PKA activation | R-HSA-163615 | 1.852434e-01 | 0.732 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 1.754945e-01 | 0.756 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 1.456917e-01 | 0.837 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 1.853038e-01 | 0.732 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 1.433612e-01 | 0.844 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 1.430432e-01 | 0.845 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.430432e-01 | 0.845 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 1.726668e-01 | 0.763 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 1.415896e-01 | 0.849 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 1.853038e-01 | 0.732 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.593010e-01 | 0.798 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.593010e-01 | 0.798 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.593010e-01 | 0.798 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 1.400172e-01 | 0.854 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.689430e-01 | 0.772 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.683514e-01 | 0.774 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.396195e-01 | 0.855 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.442142e-01 | 0.841 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.753590e-01 | 0.756 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 1.852434e-01 | 0.732 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 1.726668e-01 | 0.763 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.845252e-01 | 0.734 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 1.611694e-01 | 0.793 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 1.845417e-01 | 0.734 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.745024e-01 | 0.758 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 1.729896e-01 | 0.762 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 1.852434e-01 | 0.732 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 1.853038e-01 | 0.732 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.480860e-01 | 0.829 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 1.544166e-01 | 0.811 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.810880e-01 | 0.742 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 1.681583e-01 | 0.774 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.562729e-01 | 0.806 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 1.884313e-01 | 0.725 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.889330e-01 | 0.724 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.921270e-01 | 0.716 | 1 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.934845e-01 | 0.713 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 1.953990e-01 | 0.709 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 1.963142e-01 | 0.707 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 1.963142e-01 | 0.707 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.976617e-01 | 0.704 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 1.996097e-01 | 0.700 | 0 | 0 |
| S Phase | R-HSA-69242 | 2.013129e-01 | 0.696 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.013129e-01 | 0.696 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 2.016602e-01 | 0.695 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.298807e-01 | 0.638 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.298807e-01 | 0.638 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.298807e-01 | 0.638 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.298807e-01 | 0.638 | 0 | 0 |
| PI and PC transport between ER and Golgi membranes | R-HSA-1483196 | 3.241789e-01 | 0.489 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 3.241789e-01 | 0.489 | 0 | 0 |
| Mitochondrial transcription initiation | R-HSA-163282 | 3.241789e-01 | 0.489 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 3.241789e-01 | 0.489 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 3.241789e-01 | 0.489 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 3.241789e-01 | 0.489 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 3.241789e-01 | 0.489 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 3.241789e-01 | 0.489 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 3.241789e-01 | 0.489 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 3.241789e-01 | 0.489 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 3.241789e-01 | 0.489 | 0 | 0 |
| MyD88 deficiency (TLR5) | R-HSA-5602680 | 3.241789e-01 | 0.489 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 3.241789e-01 | 0.489 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5619101 | 3.241789e-01 | 0.489 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 3.241789e-01 | 0.489 | 0 | 0 |
| Defective MMADHC causes MMAHCD | R-HSA-3359473 | 3.241789e-01 | 0.489 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 3.241789e-01 | 0.489 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 3.241789e-01 | 0.489 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.241789e-01 | 0.489 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.241789e-01 | 0.489 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5660686 | 3.241789e-01 | 0.489 | 0 | 0 |
| Intestinal infectious diseases | R-HSA-8942233 | 3.241789e-01 | 0.489 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.327024e-01 | 0.633 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 2.327024e-01 | 0.633 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 2.081497e-01 | 0.682 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.081497e-01 | 0.682 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 2.081497e-01 | 0.682 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.807113e-01 | 0.552 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.069354e-01 | 0.390 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 4.069354e-01 | 0.390 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.069354e-01 | 0.390 | 0 | 0 |
| Interaction between PHLDA1 and AURKA | R-HSA-8854521 | 4.069354e-01 | 0.390 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.069354e-01 | 0.390 | 0 | 0 |
| HHAT G278V doesn't palmitoylate Hh-Np | R-HSA-5658034 | 4.069354e-01 | 0.390 | 0 | 0 |
| Defective DHDDS causes RP59 | R-HSA-4755609 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.069354e-01 | 0.390 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.069354e-01 | 0.390 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 4.069354e-01 | 0.390 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 4.069354e-01 | 0.390 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.069354e-01 | 0.390 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 4.069354e-01 | 0.390 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.069354e-01 | 0.390 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.069354e-01 | 0.390 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.421529e-01 | 0.616 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 3.284711e-01 | 0.484 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 3.284711e-01 | 0.484 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.769632e-01 | 0.558 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 2.769632e-01 | 0.558 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 2.769632e-01 | 0.558 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 2.769632e-01 | 0.558 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 2.383771e-01 | 0.623 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.383771e-01 | 0.623 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 2.309370e-01 | 0.637 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.309370e-01 | 0.637 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 2.665450e-01 | 0.574 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 3.122094e-01 | 0.506 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 3.753234e-01 | 0.426 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 3.753234e-01 | 0.426 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 3.753234e-01 | 0.426 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 3.753234e-01 | 0.426 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 3.753234e-01 | 0.426 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 3.753234e-01 | 0.426 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 3.753234e-01 | 0.426 | 0 | 0 |
| Defective MMACHC causes MAHCC | R-HSA-3359474 | 4.795624e-01 | 0.319 | 0 | 0 |
| Signaling by plasma membrane FGFR1 fusions | R-HSA-8853336 | 4.795624e-01 | 0.319 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 4.795624e-01 | 0.319 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.795624e-01 | 0.319 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.795624e-01 | 0.319 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 4.795624e-01 | 0.319 | 0 | 0 |
| Defective GCLC causes HAGGSD | R-HSA-5578999 | 4.795624e-01 | 0.319 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 4.795624e-01 | 0.319 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 4.795624e-01 | 0.319 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 2.223500e-01 | 0.653 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 2.223500e-01 | 0.653 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 2.223500e-01 | 0.653 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 2.952686e-01 | 0.530 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 2.952686e-01 | 0.530 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 2.135087e-01 | 0.671 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 3.475579e-01 | 0.459 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 3.475579e-01 | 0.459 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 2.322018e-01 | 0.634 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 3.243503e-01 | 0.489 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 4.207745e-01 | 0.376 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 4.207745e-01 | 0.376 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 4.207745e-01 | 0.376 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 2.514149e-01 | 0.600 | 1 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 3.827141e-01 | 0.417 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 3.827141e-01 | 0.417 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 3.536035e-01 | 0.451 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 2.208338e-01 | 0.656 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 2.133291e-01 | 0.671 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 3.828549e-01 | 0.417 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.432992e-01 | 0.265 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 5.432992e-01 | 0.265 | 0 | 0 |
| MPS VI - Maroteaux-Lamy syndrome | R-HSA-2206285 | 5.432992e-01 | 0.265 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 5.432992e-01 | 0.265 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 5.432992e-01 | 0.265 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 5.432992e-01 | 0.265 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 5.432992e-01 | 0.265 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.645108e-01 | 0.578 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.645108e-01 | 0.578 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 3.124362e-01 | 0.505 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 3.124362e-01 | 0.505 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 4.514643e-01 | 0.345 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.514643e-01 | 0.345 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 3.481975e-01 | 0.458 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 5.061455e-01 | 0.296 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 5.061455e-01 | 0.296 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 5.061455e-01 | 0.296 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 4.846579e-01 | 0.315 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 4.846579e-01 | 0.315 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 4.846579e-01 | 0.315 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 4.846579e-01 | 0.315 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 4.846579e-01 | 0.315 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 4.846579e-01 | 0.315 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 4.690864e-01 | 0.329 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 4.566157e-01 | 0.340 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 4.566157e-01 | 0.340 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 4.566157e-01 | 0.340 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 4.566157e-01 | 0.340 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 4.076000e-01 | 0.390 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 3.903850e-01 | 0.409 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 3.459408e-01 | 0.461 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 4.576474e-01 | 0.339 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 4.814132e-01 | 0.317 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 4.968950e-01 | 0.304 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 5.992335e-01 | 0.222 | 0 | 0 |
| Defective SLC1A3 causes episodic ataxia 6 (EA6) | R-HSA-5619062 | 5.992335e-01 | 0.222 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 5.992335e-01 | 0.222 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 5.992335e-01 | 0.222 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 5.992335e-01 | 0.222 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 5.992335e-01 | 0.222 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 5.992335e-01 | 0.222 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 4.909342e-01 | 0.309 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 5.058108e-01 | 0.296 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 5.240604e-01 | 0.281 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 5.129238e-01 | 0.290 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 5.479331e-01 | 0.261 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 5.297384e-01 | 0.276 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 5.297384e-01 | 0.276 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 5.504993e-01 | 0.259 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 5.504993e-01 | 0.259 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 5.828930e-01 | 0.234 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 5.828930e-01 | 0.234 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 5.828930e-01 | 0.234 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 5.425970e-01 | 0.266 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 5.583028e-01 | 0.253 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 5.759461e-01 | 0.240 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 5.759461e-01 | 0.240 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 5.678028e-01 | 0.246 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 5.800123e-01 | 0.237 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 5.981272e-01 | 0.223 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 6.064019e-01 | 0.217 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.064019e-01 | 0.217 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 6.178301e-01 | 0.209 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 6.178301e-01 | 0.209 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 3.162028e-01 | 0.500 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 4.909342e-01 | 0.309 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 5.759461e-01 | 0.240 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 3.317613e-01 | 0.479 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 3.545693e-01 | 0.450 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 5.764923e-01 | 0.239 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 5.764923e-01 | 0.239 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.605203e-01 | 0.584 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.774830e-01 | 0.423 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.275691e-01 | 0.643 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 5.058108e-01 | 0.296 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.794191e-01 | 0.554 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 2.216611e-01 | 0.654 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 5.606987e-01 | 0.251 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 2.265333e-01 | 0.645 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 4.119458e-01 | 0.385 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 3.766188e-01 | 0.424 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 3.173128e-01 | 0.499 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 4.285523e-01 | 0.368 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 6.178301e-01 | 0.209 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 2.599829e-01 | 0.585 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 5.189075e-01 | 0.285 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 5.189075e-01 | 0.285 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 3.663044e-01 | 0.436 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 5.287609e-01 | 0.277 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 5.764923e-01 | 0.239 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 2.948501e-01 | 0.530 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 2.599829e-01 | 0.585 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 4.445863e-01 | 0.352 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 5.531347e-01 | 0.257 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 6.009331e-01 | 0.221 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 4.514643e-01 | 0.345 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 4.129000e-01 | 0.384 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 3.285298e-01 | 0.483 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.421529e-01 | 0.616 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 2.421529e-01 | 0.616 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 3.536035e-01 | 0.451 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 2.496327e-01 | 0.603 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 3.302246e-01 | 0.481 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 3.302246e-01 | 0.481 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.223500e-01 | 0.653 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 2.081497e-01 | 0.682 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 2.081497e-01 | 0.682 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 2.807113e-01 | 0.552 | 0 | 0 |
| Formation of lateral plate mesoderm | R-HSA-9758920 | 2.807113e-01 | 0.552 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 2.421529e-01 | 0.616 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 2.421529e-01 | 0.616 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 2.421529e-01 | 0.616 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.753234e-01 | 0.426 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 3.243503e-01 | 0.489 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 3.827141e-01 | 0.417 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 3.243979e-01 | 0.489 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 4.846579e-01 | 0.315 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.968950e-01 | 0.304 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 5.479331e-01 | 0.261 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 2.522648e-01 | 0.598 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 2.911376e-01 | 0.536 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 2.260133e-01 | 0.646 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 2.648321e-01 | 0.577 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 5.058108e-01 | 0.296 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 5.531347e-01 | 0.257 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 4.061416e-01 | 0.391 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 4.909342e-01 | 0.309 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 3.285298e-01 | 0.483 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 2.327024e-01 | 0.633 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 2.081497e-01 | 0.682 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 2.109718e-01 | 0.676 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 4.207745e-01 | 0.376 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 4.644654e-01 | 0.333 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 5.992335e-01 | 0.222 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 5.828930e-01 | 0.234 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 5.774527e-01 | 0.238 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 6.178301e-01 | 0.209 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 6.178301e-01 | 0.209 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 2.769632e-01 | 0.558 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 2.944791e-01 | 0.531 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 3.772628e-01 | 0.423 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 2.280898e-01 | 0.642 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 5.583028e-01 | 0.253 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 2.421529e-01 | 0.616 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 2.421529e-01 | 0.616 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.548947e-01 | 0.594 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 6.064019e-01 | 0.217 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 6.178301e-01 | 0.209 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 3.903850e-01 | 0.409 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.270765e-01 | 0.644 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 5.654705e-01 | 0.248 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 6.078539e-01 | 0.216 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 6.030710e-01 | 0.220 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 2.389981e-01 | 0.622 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 2.081497e-01 | 0.682 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 2.807113e-01 | 0.552 | 0 | 0 |
| Transcription from mitochondrial promoters | R-HSA-75944 | 4.069354e-01 | 0.390 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 2.109718e-01 | 0.676 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 3.284711e-01 | 0.484 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 3.284711e-01 | 0.484 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 3.753234e-01 | 0.426 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 4.207745e-01 | 0.376 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 2.514149e-01 | 0.600 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 4.644654e-01 | 0.333 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 5.061455e-01 | 0.296 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 5.456523e-01 | 0.263 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 5.828930e-01 | 0.234 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 5.761423e-01 | 0.239 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 6.064019e-01 | 0.217 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 2.795639e-01 | 0.554 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 4.406696e-01 | 0.356 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 4.909342e-01 | 0.309 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.216611e-01 | 0.654 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 5.981272e-01 | 0.223 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 5.168537e-01 | 0.287 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 4.158917e-01 | 0.381 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 3.091439e-01 | 0.510 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 3.774830e-01 | 0.423 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 4.754891e-01 | 0.323 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 5.284982e-01 | 0.277 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 5.465210e-01 | 0.262 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 6.177996e-01 | 0.209 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 4.207745e-01 | 0.376 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 4.174223e-01 | 0.379 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 5.061455e-01 | 0.296 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 5.992335e-01 | 0.222 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 5.531347e-01 | 0.257 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 4.158917e-01 | 0.381 | 1 | 1 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 5.240604e-01 | 0.281 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 4.653623e-01 | 0.332 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.660486e-01 | 0.436 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 2.433173e-01 | 0.614 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 4.368274e-01 | 0.360 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 4.814132e-01 | 0.317 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 5.168537e-01 | 0.287 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 4.436019e-01 | 0.353 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 2.383771e-01 | 0.623 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 3.753234e-01 | 0.426 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 4.644654e-01 | 0.333 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 4.635391e-01 | 0.334 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 3.621020e-01 | 0.441 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 3.545477e-01 | 0.450 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 5.504993e-01 | 0.259 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 5.978874e-01 | 0.223 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 5.581813e-01 | 0.253 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 2.421529e-01 | 0.616 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 5.971206e-01 | 0.224 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 3.828549e-01 | 0.417 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 4.338252e-01 | 0.363 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 6.022190e-01 | 0.220 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 6.125007e-01 | 0.213 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.798230e-01 | 0.553 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.521174e-01 | 0.598 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 5.764923e-01 | 0.239 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 2.959052e-01 | 0.529 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.298807e-01 | 0.638 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 3.241789e-01 | 0.489 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.241789e-01 | 0.489 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 3.241789e-01 | 0.489 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.327024e-01 | 0.633 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 2.081497e-01 | 0.682 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 4.069354e-01 | 0.390 | 0 | 0 |
| Defective ABCC8 can cause hypo- and hyper-glycemias | R-HSA-5683177 | 4.069354e-01 | 0.390 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.069354e-01 | 0.390 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 4.069354e-01 | 0.390 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 2.769632e-01 | 0.558 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 3.122094e-01 | 0.506 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 3.122094e-01 | 0.506 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 3.753234e-01 | 0.426 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 4.795624e-01 | 0.319 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.475579e-01 | 0.459 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 2.750575e-01 | 0.561 | 0 | 0 |
| Electric Transmission Across Gap Junctions | R-HSA-112303 | 5.432992e-01 | 0.265 | 0 | 0 |
| Transmission across Electrical Synapses | R-HSA-112307 | 5.432992e-01 | 0.265 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 5.432992e-01 | 0.265 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 5.061455e-01 | 0.296 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 5.061455e-01 | 0.296 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 4.314962e-01 | 0.365 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 4.968950e-01 | 0.304 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 5.456523e-01 | 0.263 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 5.456523e-01 | 0.263 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 5.992335e-01 | 0.222 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 5.992335e-01 | 0.222 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 4.485086e-01 | 0.348 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 4.267827e-01 | 0.370 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 4.908814e-01 | 0.309 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 5.778047e-01 | 0.238 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 5.961950e-01 | 0.225 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 6.009331e-01 | 0.221 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 4.895829e-01 | 0.310 | 1 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 3.265576e-01 | 0.486 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 3.265576e-01 | 0.486 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 5.778047e-01 | 0.238 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 6.009331e-01 | 0.221 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 3.893743e-01 | 0.410 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 3.321427e-01 | 0.479 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 5.967407e-01 | 0.224 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 3.026564e-01 | 0.519 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 2.514149e-01 | 0.600 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 6.064019e-01 | 0.217 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 2.795639e-01 | 0.554 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 2.105540e-01 | 0.677 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.794191e-01 | 0.554 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 4.207745e-01 | 0.376 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 5.168537e-01 | 0.287 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 4.313050e-01 | 0.365 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 5.606789e-01 | 0.251 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 5.961950e-01 | 0.225 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 2.807113e-01 | 0.552 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 3.284711e-01 | 0.484 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.383771e-01 | 0.623 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 3.753234e-01 | 0.426 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 3.753234e-01 | 0.426 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 3.243503e-01 | 0.489 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 4.207745e-01 | 0.376 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 4.644654e-01 | 0.333 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 4.644654e-01 | 0.333 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 4.644654e-01 | 0.333 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 5.432992e-01 | 0.265 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 4.119458e-01 | 0.385 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 3.285298e-01 | 0.483 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 5.981272e-01 | 0.223 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.971206e-01 | 0.224 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 2.879668e-01 | 0.541 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 5.189075e-01 | 0.285 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 2.126247e-01 | 0.672 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 2.270765e-01 | 0.644 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 4.644654e-01 | 0.333 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 5.553131e-01 | 0.255 | 1 | 1 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 6.178301e-01 | 0.209 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 4.716416e-01 | 0.326 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 3.315033e-01 | 0.480 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 5.998210e-01 | 0.222 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 3.828549e-01 | 0.417 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 3.328414e-01 | 0.478 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 4.909342e-01 | 0.309 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.314962e-01 | 0.365 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 4.069354e-01 | 0.390 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 4.069354e-01 | 0.390 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 4.069354e-01 | 0.390 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 2.665450e-01 | 0.574 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 4.795624e-01 | 0.319 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 4.207745e-01 | 0.376 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 3.827141e-01 | 0.417 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 2.710824e-01 | 0.567 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 2.775335e-01 | 0.557 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 2.952629e-01 | 0.530 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 3.315033e-01 | 0.480 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 5.061455e-01 | 0.296 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 5.061455e-01 | 0.296 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.846579e-01 | 0.315 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 4.814132e-01 | 0.317 | 0 | 0 |
| Biosynthesis of DPAn-3-derived 13-series resolvins | R-HSA-9026403 | 5.992335e-01 | 0.222 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 5.992335e-01 | 0.222 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 5.828930e-01 | 0.234 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 5.095897e-01 | 0.293 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 2.514149e-01 | 0.600 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 4.479607e-01 | 0.349 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 5.387763e-01 | 0.269 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 3.545746e-01 | 0.450 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 3.284711e-01 | 0.484 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 4.795624e-01 | 0.319 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 5.168537e-01 | 0.287 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 3.878626e-01 | 0.411 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 4.514643e-01 | 0.345 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 4.407324e-01 | 0.356 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 5.240604e-01 | 0.281 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 2.775335e-01 | 0.557 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 3.753234e-01 | 0.426 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 3.753234e-01 | 0.426 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 4.207745e-01 | 0.376 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 4.207745e-01 | 0.376 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.432992e-01 | 0.265 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 5.432992e-01 | 0.265 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 5.061455e-01 | 0.296 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 5.240604e-01 | 0.281 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 5.981272e-01 | 0.223 | 0 | 0 |
| Estrogen biosynthesis | R-HSA-193144 | 6.178301e-01 | 0.209 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 6.178301e-01 | 0.209 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 6.178301e-01 | 0.209 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 2.179683e-01 | 0.662 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 5.163804e-01 | 0.287 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.802731e-01 | 0.552 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 4.909342e-01 | 0.309 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 6.064019e-01 | 0.217 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.807113e-01 | 0.552 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 4.514643e-01 | 0.345 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 5.456523e-01 | 0.263 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 2.223500e-01 | 0.653 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 4.663333e-01 | 0.331 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 3.536035e-01 | 0.451 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 5.297384e-01 | 0.276 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 5.778047e-01 | 0.238 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 6.178301e-01 | 0.209 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 3.827141e-01 | 0.417 | 1 | 1 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 5.061455e-01 | 0.296 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 3.586891e-01 | 0.445 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 5.981272e-01 | 0.223 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.828549e-01 | 0.417 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 5.154106e-01 | 0.288 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 6.178301e-01 | 0.209 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 5.168537e-01 | 0.287 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 5.778047e-01 | 0.238 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 4.174223e-01 | 0.379 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.368444e-01 | 0.270 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 5.061455e-01 | 0.296 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 3.536035e-01 | 0.451 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 4.968950e-01 | 0.304 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 6.196400e-01 | 0.208 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 6.196400e-01 | 0.208 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 6.196400e-01 | 0.208 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 6.248273e-01 | 0.204 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 6.336798e-01 | 0.198 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 6.336798e-01 | 0.198 | 1 | 1 |
| Creatine metabolism | R-HSA-71288 | 6.336798e-01 | 0.198 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 6.336798e-01 | 0.198 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 6.356255e-01 | 0.197 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 6.390573e-01 | 0.194 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.396141e-01 | 0.194 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 6.404535e-01 | 0.194 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 6.404535e-01 | 0.194 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 6.423546e-01 | 0.192 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 6.464719e-01 | 0.189 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 6.477919e-01 | 0.189 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 6.477919e-01 | 0.189 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.483201e-01 | 0.188 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 6.483201e-01 | 0.188 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.483201e-01 | 0.188 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 6.483201e-01 | 0.188 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.483201e-01 | 0.188 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.483201e-01 | 0.188 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 6.483201e-01 | 0.188 | 0 | 0 |
| Phase 1 - inactivation of fast Na+ channels | R-HSA-5576894 | 6.483201e-01 | 0.188 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 6.483201e-01 | 0.188 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 6.483201e-01 | 0.188 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 6.483201e-01 | 0.188 | 0 | 0 |
| Formation of the Editosome | R-HSA-75094 | 6.483201e-01 | 0.188 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 6.483201e-01 | 0.188 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.483201e-01 | 0.188 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 6.483201e-01 | 0.188 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.483201e-01 | 0.188 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 6.483201e-01 | 0.188 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 6.483201e-01 | 0.188 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 6.483201e-01 | 0.188 | 0 | 0 |
| Acetylcholine inhibits contraction of outer hair cells | R-HSA-9667769 | 6.483201e-01 | 0.188 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 6.483201e-01 | 0.188 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 6.483201e-01 | 0.188 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 6.504691e-01 | 0.187 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 6.504691e-01 | 0.187 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 6.504691e-01 | 0.187 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 6.542123e-01 | 0.184 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 6.596123e-01 | 0.181 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 6.596123e-01 | 0.181 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 6.596123e-01 | 0.181 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 6.596123e-01 | 0.181 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 6.605437e-01 | 0.180 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 6.649997e-01 | 0.177 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 6.649997e-01 | 0.177 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 6.649997e-01 | 0.177 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 6.698039e-01 | 0.174 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 6.698039e-01 | 0.174 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 6.698039e-01 | 0.174 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 6.722032e-01 | 0.172 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 6.779151e-01 | 0.169 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 6.779151e-01 | 0.169 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 6.794201e-01 | 0.168 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 6.797552e-01 | 0.168 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 6.798926e-01 | 0.168 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 6.804148e-01 | 0.167 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 6.808488e-01 | 0.167 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 6.808488e-01 | 0.167 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 6.808488e-01 | 0.167 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 6.808488e-01 | 0.167 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 6.808488e-01 | 0.167 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 6.808488e-01 | 0.167 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 6.829648e-01 | 0.166 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 6.841898e-01 | 0.165 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 6.841898e-01 | 0.165 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 6.841898e-01 | 0.165 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 6.846779e-01 | 0.165 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 6.879375e-01 | 0.162 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 6.883644e-01 | 0.162 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 6.887340e-01 | 0.162 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 6.895843e-01 | 0.161 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 6.895843e-01 | 0.161 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 6.895843e-01 | 0.161 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 6.895843e-01 | 0.161 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 6.895843e-01 | 0.161 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 6.895843e-01 | 0.161 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 6.908495e-01 | 0.161 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 6.908495e-01 | 0.161 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 6.908495e-01 | 0.161 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 6.913970e-01 | 0.160 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 6.913970e-01 | 0.160 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 6.913970e-01 | 0.160 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 6.913970e-01 | 0.160 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 6.913970e-01 | 0.160 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 6.913970e-01 | 0.160 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 6.913970e-01 | 0.160 | 0 | 0 |
| Lipid particle organization | R-HSA-8964572 | 6.913970e-01 | 0.160 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.946121e-01 | 0.158 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 6.968380e-01 | 0.157 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 6.970419e-01 | 0.157 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 6.980900e-01 | 0.156 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 6.984880e-01 | 0.156 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 6.984880e-01 | 0.156 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 6.984880e-01 | 0.156 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 6.984880e-01 | 0.156 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 6.988107e-01 | 0.156 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 7.063457e-01 | 0.151 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 7.071989e-01 | 0.150 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 7.074166e-01 | 0.150 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 7.074166e-01 | 0.150 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 7.074166e-01 | 0.150 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.074166e-01 | 0.150 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 7.074166e-01 | 0.150 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 7.074166e-01 | 0.150 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 7.074166e-01 | 0.150 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 7.090330e-01 | 0.149 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 7.090330e-01 | 0.149 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 7.090330e-01 | 0.149 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 7.090330e-01 | 0.149 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 7.090330e-01 | 0.149 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 7.090330e-01 | 0.149 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.090330e-01 | 0.149 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 7.090330e-01 | 0.149 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 7.090330e-01 | 0.149 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 7.090330e-01 | 0.149 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 7.099866e-01 | 0.149 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 7.109230e-01 | 0.148 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 7.109230e-01 | 0.148 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 7.159041e-01 | 0.145 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 7.163231e-01 | 0.145 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 7.163231e-01 | 0.145 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 7.163231e-01 | 0.145 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 7.177380e-01 | 0.144 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 7.209054e-01 | 0.142 | 1 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 7.209054e-01 | 0.142 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 7.209054e-01 | 0.142 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 7.217177e-01 | 0.142 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 7.240957e-01 | 0.140 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 7.289145e-01 | 0.137 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 7.291997e-01 | 0.137 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.291997e-01 | 0.137 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 7.291997e-01 | 0.137 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 7.291997e-01 | 0.137 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 7.291997e-01 | 0.137 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 7.291997e-01 | 0.137 | 0 | 0 |
| mRNA Editing: C to U Conversion | R-HSA-72200 | 7.291997e-01 | 0.137 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 7.291997e-01 | 0.137 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 7.291997e-01 | 0.137 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 7.291997e-01 | 0.137 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 7.291997e-01 | 0.137 | 0 | 0 |
| Glycoprotein hormones | R-HSA-209822 | 7.291997e-01 | 0.137 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.291997e-01 | 0.137 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.293087e-01 | 0.137 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 7.316589e-01 | 0.136 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 7.333958e-01 | 0.135 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 7.333958e-01 | 0.135 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 7.333958e-01 | 0.135 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 7.348230e-01 | 0.134 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 7.351036e-01 | 0.134 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 7.351036e-01 | 0.134 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 7.351036e-01 | 0.134 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 7.351036e-01 | 0.134 | 0 | 0 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 7.351036e-01 | 0.134 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 7.353943e-01 | 0.133 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 7.385895e-01 | 0.132 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 7.418056e-01 | 0.130 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 7.423830e-01 | 0.129 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 7.424370e-01 | 0.129 | 1 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 7.431637e-01 | 0.129 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 7.478104e-01 | 0.126 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.481670e-01 | 0.126 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 7.481670e-01 | 0.126 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 7.489389e-01 | 0.126 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 7.497082e-01 | 0.125 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 7.497082e-01 | 0.125 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 7.498918e-01 | 0.125 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 7.498918e-01 | 0.125 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.498918e-01 | 0.125 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.498918e-01 | 0.125 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.520874e-01 | 0.124 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 7.528660e-01 | 0.123 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 7.541343e-01 | 0.123 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 7.541343e-01 | 0.123 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 7.543676e-01 | 0.122 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 7.558579e-01 | 0.122 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 7.568765e-01 | 0.121 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 7.568765e-01 | 0.121 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 7.591554e-01 | 0.120 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 7.591554e-01 | 0.120 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 7.591554e-01 | 0.120 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 7.591554e-01 | 0.120 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 7.591554e-01 | 0.120 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 7.591554e-01 | 0.120 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 7.591554e-01 | 0.120 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 7.591554e-01 | 0.120 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.591554e-01 | 0.120 | 0 | 0 |
| RSK activation | R-HSA-444257 | 7.623736e-01 | 0.118 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 7.623736e-01 | 0.118 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 7.623736e-01 | 0.118 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 7.623736e-01 | 0.118 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.623736e-01 | 0.118 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 7.623736e-01 | 0.118 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 7.623736e-01 | 0.118 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 7.623736e-01 | 0.118 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 7.623736e-01 | 0.118 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 7.623736e-01 | 0.118 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.623736e-01 | 0.118 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 7.623736e-01 | 0.118 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 7.623736e-01 | 0.118 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 7.623736e-01 | 0.118 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 7.650142e-01 | 0.116 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 7.652666e-01 | 0.116 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 7.652666e-01 | 0.116 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 7.653589e-01 | 0.116 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 7.653589e-01 | 0.116 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 7.653589e-01 | 0.116 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 7.653589e-01 | 0.116 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 7.666896e-01 | 0.115 | 1 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.671184e-01 | 0.115 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 7.691996e-01 | 0.114 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 7.691996e-01 | 0.114 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 7.691996e-01 | 0.114 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 7.691996e-01 | 0.114 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 7.691996e-01 | 0.114 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.691996e-01 | 0.114 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 7.700544e-01 | 0.113 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 7.774951e-01 | 0.109 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 7.812917e-01 | 0.107 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 7.812917e-01 | 0.107 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 7.812917e-01 | 0.107 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 7.816201e-01 | 0.107 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 7.816201e-01 | 0.107 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 7.816201e-01 | 0.107 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 7.816201e-01 | 0.107 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 7.816201e-01 | 0.107 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 7.852491e-01 | 0.105 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.852491e-01 | 0.105 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 7.872719e-01 | 0.104 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 7.901938e-01 | 0.102 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 7.914853e-01 | 0.102 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 7.914853e-01 | 0.102 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 7.914853e-01 | 0.102 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 7.914853e-01 | 0.102 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 7.914853e-01 | 0.102 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 7.914853e-01 | 0.102 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 7.914853e-01 | 0.102 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 7.914853e-01 | 0.102 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 7.914853e-01 | 0.102 | 0 | 0 |
| Lysosomal oligosaccharide catabolism | R-HSA-8853383 | 7.914853e-01 | 0.102 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 7.914853e-01 | 0.102 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 7.937711e-01 | 0.100 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 7.937711e-01 | 0.100 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 7.937711e-01 | 0.100 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 7.937711e-01 | 0.100 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 7.941623e-01 | 0.100 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 7.948220e-01 | 0.100 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 7.969727e-01 | 0.099 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 7.995800e-01 | 0.097 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 8.016209e-01 | 0.096 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 8.016209e-01 | 0.096 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 8.016209e-01 | 0.096 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 8.016209e-01 | 0.096 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.016209e-01 | 0.096 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 8.016209e-01 | 0.096 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 8.041537e-01 | 0.095 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.041537e-01 | 0.095 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 8.041537e-01 | 0.095 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 8.041537e-01 | 0.095 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.045435e-01 | 0.094 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 8.064240e-01 | 0.093 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 8.076655e-01 | 0.093 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 8.076655e-01 | 0.093 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 8.088972e-01 | 0.092 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 8.114422e-01 | 0.091 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 8.114422e-01 | 0.091 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 8.114422e-01 | 0.091 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 8.169958e-01 | 0.088 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 8.170320e-01 | 0.088 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 8.170320e-01 | 0.088 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 8.170320e-01 | 0.088 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 8.170320e-01 | 0.088 | 0 | 0 |
| Arachidonate production from DAG | R-HSA-426048 | 8.170320e-01 | 0.088 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 8.170320e-01 | 0.088 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 8.170320e-01 | 0.088 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 8.170320e-01 | 0.088 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 8.170320e-01 | 0.088 | 0 | 0 |
| Peptide hormone biosynthesis | R-HSA-209952 | 8.170320e-01 | 0.088 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 8.170320e-01 | 0.088 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 8.170320e-01 | 0.088 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 8.181082e-01 | 0.087 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.185756e-01 | 0.087 | 1 | 1 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 8.194379e-01 | 0.086 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 8.198934e-01 | 0.086 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 8.198934e-01 | 0.086 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 8.198934e-01 | 0.086 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 8.198934e-01 | 0.086 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 8.198934e-01 | 0.086 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 8.201922e-01 | 0.086 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 8.201922e-01 | 0.086 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 8.202532e-01 | 0.086 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 8.202532e-01 | 0.086 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 8.234893e-01 | 0.084 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 8.234893e-01 | 0.084 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 8.250566e-01 | 0.084 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 8.250566e-01 | 0.084 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 8.281056e-01 | 0.082 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 8.281056e-01 | 0.082 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 8.281056e-01 | 0.082 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 8.281089e-01 | 0.082 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 8.287027e-01 | 0.082 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 8.321767e-01 | 0.080 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 8.340682e-01 | 0.079 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.345419e-01 | 0.079 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 8.345419e-01 | 0.079 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 8.345419e-01 | 0.079 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 8.345419e-01 | 0.079 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 8.360344e-01 | 0.078 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 8.372994e-01 | 0.077 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 8.372994e-01 | 0.077 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.382055e-01 | 0.077 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 8.394501e-01 | 0.076 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 8.394501e-01 | 0.076 | 0 | 0 |
| Presynaptic depolarization and calcium channel opening | R-HSA-112308 | 8.394501e-01 | 0.076 | 0 | 0 |
| FGFR2b ligand binding and activation | R-HSA-190377 | 8.394501e-01 | 0.076 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 8.394501e-01 | 0.076 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 8.394501e-01 | 0.076 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 8.394501e-01 | 0.076 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 8.394501e-01 | 0.076 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 8.394501e-01 | 0.076 | 0 | 0 |
| Biosynthesis of DPAn-3-derived maresins | R-HSA-9026290 | 8.394501e-01 | 0.076 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 8.394501e-01 | 0.076 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 8.394501e-01 | 0.076 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 8.394501e-01 | 0.076 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 8.394501e-01 | 0.076 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 8.394501e-01 | 0.076 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 8.399518e-01 | 0.076 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 8.419430e-01 | 0.075 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 8.435013e-01 | 0.074 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 8.459274e-01 | 0.073 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 8.459274e-01 | 0.073 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 8.481519e-01 | 0.072 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 8.481519e-01 | 0.072 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 8.481519e-01 | 0.072 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.481519e-01 | 0.072 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 8.528683e-01 | 0.069 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 8.528683e-01 | 0.069 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 8.528683e-01 | 0.069 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 8.528683e-01 | 0.069 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 8.528683e-01 | 0.069 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 8.528683e-01 | 0.069 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 8.528683e-01 | 0.069 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 8.591225e-01 | 0.066 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 8.591225e-01 | 0.066 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 8.591225e-01 | 0.066 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 8.591225e-01 | 0.066 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 8.591225e-01 | 0.066 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.591225e-01 | 0.066 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.591225e-01 | 0.066 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 8.591225e-01 | 0.066 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 8.591225e-01 | 0.066 | 0 | 0 |
| Uptake of dietary cobalamins into enterocytes | R-HSA-9758881 | 8.591225e-01 | 0.066 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 8.596298e-01 | 0.066 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 8.607769e-01 | 0.065 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.607769e-01 | 0.065 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 8.607769e-01 | 0.065 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 8.610777e-01 | 0.065 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 8.610777e-01 | 0.065 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 8.610777e-01 | 0.065 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 8.629895e-01 | 0.064 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 8.642590e-01 | 0.063 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 8.642590e-01 | 0.063 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 8.670659e-01 | 0.062 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 8.670659e-01 | 0.062 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 8.670659e-01 | 0.062 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 8.670659e-01 | 0.062 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.670659e-01 | 0.062 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 8.687909e-01 | 0.061 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.687909e-01 | 0.061 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 8.715864e-01 | 0.060 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 8.715864e-01 | 0.060 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.737384e-01 | 0.059 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 8.763855e-01 | 0.057 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 8.763855e-01 | 0.057 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 8.763855e-01 | 0.057 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.763855e-01 | 0.057 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 8.763855e-01 | 0.057 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 8.763855e-01 | 0.057 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 8.763855e-01 | 0.057 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 8.763855e-01 | 0.057 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 8.763855e-01 | 0.057 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 8.763855e-01 | 0.057 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.763855e-01 | 0.057 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 8.763855e-01 | 0.057 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 8.763855e-01 | 0.057 | 0 | 0 |
| Biosynthesis of DPAn-3-derived protectins and resolvins | R-HSA-9026286 | 8.763855e-01 | 0.057 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 8.763855e-01 | 0.057 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.763855e-01 | 0.057 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 8.763958e-01 | 0.057 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 8.770897e-01 | 0.057 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 8.773878e-01 | 0.057 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 8.773878e-01 | 0.057 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 8.779599e-01 | 0.057 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 8.789506e-01 | 0.056 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 8.799944e-01 | 0.056 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 8.799944e-01 | 0.056 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 8.799944e-01 | 0.056 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 8.814021e-01 | 0.055 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 8.814021e-01 | 0.055 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 8.814021e-01 | 0.055 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 8.814021e-01 | 0.055 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 8.814021e-01 | 0.055 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 8.817830e-01 | 0.055 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 8.826498e-01 | 0.054 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 8.826498e-01 | 0.054 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 8.832857e-01 | 0.054 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 8.855064e-01 | 0.053 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.855064e-01 | 0.053 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 8.865240e-01 | 0.052 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.892090e-01 | 0.051 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 8.905586e-01 | 0.050 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.910175e-01 | 0.050 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 8.915339e-01 | 0.050 | 0 | 0 |
| FGFR2c ligand binding and activation | R-HSA-190375 | 8.915339e-01 | 0.050 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 8.915339e-01 | 0.050 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.915339e-01 | 0.050 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 8.915339e-01 | 0.050 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 8.915339e-01 | 0.050 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.915339e-01 | 0.050 | 0 | 0 |
| Mtb iron assimilation by chelation | R-HSA-1222449 | 8.915339e-01 | 0.050 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 8.915339e-01 | 0.050 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 8.915339e-01 | 0.050 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 8.915339e-01 | 0.050 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 8.915339e-01 | 0.050 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 8.915339e-01 | 0.050 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.915339e-01 | 0.050 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 8.917516e-01 | 0.050 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 8.917516e-01 | 0.050 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 8.917516e-01 | 0.050 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 8.917516e-01 | 0.050 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 8.917516e-01 | 0.050 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 8.917516e-01 | 0.050 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 8.931652e-01 | 0.049 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 8.931652e-01 | 0.049 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 8.931652e-01 | 0.049 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 8.988656e-01 | 0.046 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.988656e-01 | 0.046 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 8.990898e-01 | 0.046 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 8.990898e-01 | 0.046 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.014115e-01 | 0.045 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 9.024304e-01 | 0.045 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.024304e-01 | 0.045 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 9.024304e-01 | 0.045 | 0 | 0 |
| Synthesis of dolichyl-phosphate | R-HSA-446199 | 9.024304e-01 | 0.045 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.024304e-01 | 0.045 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.024899e-01 | 0.045 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.024899e-01 | 0.045 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.032530e-01 | 0.044 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 9.042522e-01 | 0.044 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 9.048268e-01 | 0.043 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 9.048268e-01 | 0.043 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 9.048268e-01 | 0.043 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 9.048268e-01 | 0.043 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 9.048268e-01 | 0.043 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 9.048268e-01 | 0.043 | 0 | 0 |
| The activation of arylsulfatases | R-HSA-1663150 | 9.048268e-01 | 0.043 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 9.048268e-01 | 0.043 | 0 | 0 |
| Biosynthesis of E-series 18(R)-resolvins | R-HSA-9023661 | 9.048268e-01 | 0.043 | 0 | 0 |
| Vitamin B2 (riboflavin) metabolism | R-HSA-196843 | 9.048268e-01 | 0.043 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 9.048268e-01 | 0.043 | 0 | 0 |
| Glycerophospholipid catabolism | R-HSA-6814848 | 9.048268e-01 | 0.043 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 9.048268e-01 | 0.043 | 0 | 0 |
| Ciprofloxacin ADME | R-HSA-9793528 | 9.048268e-01 | 0.043 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 9.048268e-01 | 0.043 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 9.048268e-01 | 0.043 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 9.048268e-01 | 0.043 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.070288e-01 | 0.042 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 9.070288e-01 | 0.042 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.109797e-01 | 0.040 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.109797e-01 | 0.040 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.109797e-01 | 0.040 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.109797e-01 | 0.040 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.109797e-01 | 0.040 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 9.117670e-01 | 0.040 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.121185e-01 | 0.040 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.121185e-01 | 0.040 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 9.131300e-01 | 0.039 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.142723e-01 | 0.039 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.142723e-01 | 0.039 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.142723e-01 | 0.039 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.144085e-01 | 0.039 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.144085e-01 | 0.039 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 9.164913e-01 | 0.038 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 9.164913e-01 | 0.038 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 9.164913e-01 | 0.038 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 9.164913e-01 | 0.038 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 9.164913e-01 | 0.038 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 9.164913e-01 | 0.038 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 9.164913e-01 | 0.038 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 9.164913e-01 | 0.038 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 9.178518e-01 | 0.037 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.187923e-01 | 0.037 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.187923e-01 | 0.037 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 9.195332e-01 | 0.036 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.198336e-01 | 0.036 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 9.208981e-01 | 0.036 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 9.208981e-01 | 0.036 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 9.208981e-01 | 0.036 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.208981e-01 | 0.036 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.208981e-01 | 0.036 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.208981e-01 | 0.036 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 9.212607e-01 | 0.036 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.212607e-01 | 0.036 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.212607e-01 | 0.036 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.212607e-01 | 0.036 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.224780e-01 | 0.035 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.245301e-01 | 0.034 | 1 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.259599e-01 | 0.033 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.259738e-01 | 0.033 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 9.267267e-01 | 0.033 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 9.267267e-01 | 0.033 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 9.267267e-01 | 0.033 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 9.267267e-01 | 0.033 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 9.267267e-01 | 0.033 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 9.267267e-01 | 0.033 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 9.267267e-01 | 0.033 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.267267e-01 | 0.033 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 9.267267e-01 | 0.033 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 9.267267e-01 | 0.033 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 9.267267e-01 | 0.033 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 9.267267e-01 | 0.033 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 9.267267e-01 | 0.033 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 9.276163e-01 | 0.033 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.288465e-01 | 0.032 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 9.288465e-01 | 0.032 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.288465e-01 | 0.032 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.288465e-01 | 0.032 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.288465e-01 | 0.032 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 9.304933e-01 | 0.031 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.325681e-01 | 0.030 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 9.335054e-01 | 0.030 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.335054e-01 | 0.030 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 9.357081e-01 | 0.029 | 1 | 1 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.357081e-01 | 0.029 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.357081e-01 | 0.029 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.357081e-01 | 0.029 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 9.357081e-01 | 0.029 | 0 | 0 |
| Vitamin B6 activation to pyridoxal phosphate | R-HSA-964975 | 9.357081e-01 | 0.029 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 9.357081e-01 | 0.029 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 9.357081e-01 | 0.029 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 9.357081e-01 | 0.029 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.357081e-01 | 0.029 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 9.357081e-01 | 0.029 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.363860e-01 | 0.029 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 9.366586e-01 | 0.028 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 9.377557e-01 | 0.028 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.386170e-01 | 0.028 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.386170e-01 | 0.028 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 9.425317e-01 | 0.026 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.425317e-01 | 0.026 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 9.425317e-01 | 0.026 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 9.435891e-01 | 0.025 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 9.435891e-01 | 0.025 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.435891e-01 | 0.025 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.435891e-01 | 0.025 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 9.435891e-01 | 0.025 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 9.435891e-01 | 0.025 | 0 | 0 |
| Biosynthesis of aspirin-triggered D-series resolvins | R-HSA-9020265 | 9.435891e-01 | 0.025 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 9.435891e-01 | 0.025 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 9.435891e-01 | 0.025 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 9.435891e-01 | 0.025 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 9.435891e-01 | 0.025 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 9.435891e-01 | 0.025 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 9.435891e-01 | 0.025 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 9.435891e-01 | 0.025 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 9.435891e-01 | 0.025 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 9.441603e-01 | 0.025 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 9.441603e-01 | 0.025 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 9.441603e-01 | 0.025 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 9.453278e-01 | 0.024 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.459781e-01 | 0.024 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 9.465105e-01 | 0.024 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.478660e-01 | 0.023 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.478660e-01 | 0.023 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.483970e-01 | 0.023 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.486565e-01 | 0.023 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.486565e-01 | 0.023 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.492354e-01 | 0.023 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.492354e-01 | 0.023 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 9.499834e-01 | 0.022 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 9.505045e-01 | 0.022 | 0 | 0 |
| Activated point mutants of FGFR2 | R-HSA-2033519 | 9.505045e-01 | 0.022 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 9.505045e-01 | 0.022 | 0 | 0 |
| Biosynthesis of Lipoxins (LX) | R-HSA-2142700 | 9.505045e-01 | 0.022 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.505045e-01 | 0.022 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.505045e-01 | 0.022 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 9.505045e-01 | 0.022 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 9.505045e-01 | 0.022 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.515917e-01 | 0.022 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 9.529566e-01 | 0.021 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 9.536883e-01 | 0.021 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.536883e-01 | 0.021 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 9.536883e-01 | 0.021 | 0 | 0 |
| Synthesis of glycosylphosphatidylinositol (GPI) | R-HSA-162710 | 9.536883e-01 | 0.021 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.536883e-01 | 0.021 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.538778e-01 | 0.021 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.548437e-01 | 0.020 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 9.565724e-01 | 0.019 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.565724e-01 | 0.019 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 9.565724e-01 | 0.019 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 9.565724e-01 | 0.019 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.565724e-01 | 0.019 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.565724e-01 | 0.019 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 9.569229e-01 | 0.019 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.581207e-01 | 0.019 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.581207e-01 | 0.019 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.584582e-01 | 0.018 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.605781e-01 | 0.017 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 9.612061e-01 | 0.017 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.618968e-01 | 0.017 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.618968e-01 | 0.017 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 9.618968e-01 | 0.017 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 9.618968e-01 | 0.017 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.618968e-01 | 0.017 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 9.619953e-01 | 0.017 | 0 | 0 |
| Defective B3GALTL causes PpS | R-HSA-5083635 | 9.627551e-01 | 0.016 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 9.639441e-01 | 0.016 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 9.639441e-01 | 0.016 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 9.640013e-01 | 0.016 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.650182e-01 | 0.015 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.655308e-01 | 0.015 | 0 | 0 |
| FGFR2 ligand binding and activation | R-HSA-190241 | 9.665686e-01 | 0.015 | 0 | 0 |
| Biosynthesis of E-series 18(S)-resolvins | R-HSA-9018896 | 9.665686e-01 | 0.015 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 9.665686e-01 | 0.015 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 9.665686e-01 | 0.015 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.665686e-01 | 0.015 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 9.665686e-01 | 0.015 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.665686e-01 | 0.015 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 9.665686e-01 | 0.015 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 9.665686e-01 | 0.015 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.666231e-01 | 0.015 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.669051e-01 | 0.015 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.670412e-01 | 0.015 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.670412e-01 | 0.015 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.676779e-01 | 0.014 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.687543e-01 | 0.014 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.687543e-01 | 0.014 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.695264e-01 | 0.013 | 1 | 0 |
| eNOS activation | R-HSA-203615 | 9.701028e-01 | 0.013 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.701028e-01 | 0.013 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 9.701028e-01 | 0.013 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.701028e-01 | 0.013 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.701028e-01 | 0.013 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.701510e-01 | 0.013 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 9.706679e-01 | 0.013 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 9.706679e-01 | 0.013 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.706679e-01 | 0.013 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.706679e-01 | 0.013 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.721851e-01 | 0.012 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 9.724489e-01 | 0.012 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.732312e-01 | 0.012 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.742647e-01 | 0.011 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 9.742647e-01 | 0.011 | 0 | 0 |
| Biosynthesis of D-series resolvins | R-HSA-9018676 | 9.742647e-01 | 0.011 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.742647e-01 | 0.011 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 9.742647e-01 | 0.011 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.742647e-01 | 0.011 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.742647e-01 | 0.011 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 9.747432e-01 | 0.011 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.749073e-01 | 0.011 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.752294e-01 | 0.011 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.764485e-01 | 0.010 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.767982e-01 | 0.010 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.771112e-01 | 0.010 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.774207e-01 | 0.010 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.774207e-01 | 0.010 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.774207e-01 | 0.010 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.774207e-01 | 0.010 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.774207e-01 | 0.010 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.774207e-01 | 0.010 | 0 | 0 |
| O-glycosylation of TSR domain-containing proteins | R-HSA-5173214 | 9.785666e-01 | 0.009 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.785666e-01 | 0.009 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 9.785666e-01 | 0.009 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.785666e-01 | 0.009 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.785666e-01 | 0.009 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.788703e-01 | 0.009 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.790103e-01 | 0.009 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 9.791319e-01 | 0.009 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 9.801898e-01 | 0.009 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.801898e-01 | 0.009 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.801898e-01 | 0.009 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.801898e-01 | 0.009 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.801898e-01 | 0.009 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.805708e-01 | 0.009 | 1 | 1 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.808323e-01 | 0.008 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.809835e-01 | 0.008 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.819400e-01 | 0.008 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.826194e-01 | 0.008 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.826194e-01 | 0.008 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.826194e-01 | 0.008 | 0 | 0 |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | R-HSA-9027604 | 9.826194e-01 | 0.008 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.826194e-01 | 0.008 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.826194e-01 | 0.008 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.828648e-01 | 0.008 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.828648e-01 | 0.008 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 9.844861e-01 | 0.007 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.847512e-01 | 0.007 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 9.847512e-01 | 0.007 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.847512e-01 | 0.007 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 9.857343e-01 | 0.006 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.861976e-01 | 0.006 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.863206e-01 | 0.006 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 9.866216e-01 | 0.006 | 0 | 0 |
| Cobalamin (Cbl) metabolism | R-HSA-9759218 | 9.866216e-01 | 0.006 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.866216e-01 | 0.006 | 0 | 0 |
| Biosynthesis of DPAn-3 SPMs | R-HSA-9025094 | 9.866216e-01 | 0.006 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.866216e-01 | 0.006 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.872556e-01 | 0.006 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.872556e-01 | 0.006 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.879532e-01 | 0.005 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.880713e-01 | 0.005 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.882627e-01 | 0.005 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 9.886015e-01 | 0.005 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.887126e-01 | 0.005 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.890938e-01 | 0.005 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.892141e-01 | 0.005 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 9.893495e-01 | 0.005 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.897026e-01 | 0.004 | 0 | 0 |
| Biosynthesis of EPA-derived SPMs | R-HSA-9018679 | 9.897026e-01 | 0.004 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.897026e-01 | 0.004 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.897026e-01 | 0.004 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.897155e-01 | 0.004 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.902665e-01 | 0.004 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.905775e-01 | 0.004 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 9.906808e-01 | 0.004 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.907309e-01 | 0.004 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.907309e-01 | 0.004 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 9.909659e-01 | 0.004 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.909659e-01 | 0.004 | 0 | 0 |
| Mucopolysaccharidoses | R-HSA-2206281 | 9.909659e-01 | 0.004 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.913156e-01 | 0.004 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.914520e-01 | 0.004 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.914520e-01 | 0.004 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.918885e-01 | 0.004 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.919233e-01 | 0.004 | 0 | 0 |
| Biosynthesis of DPA-derived SPMs | R-HSA-9018683 | 9.920743e-01 | 0.003 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 9.920743e-01 | 0.003 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.924738e-01 | 0.003 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.928168e-01 | 0.003 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.930467e-01 | 0.003 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.930928e-01 | 0.003 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 9.933617e-01 | 0.003 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 9.938425e-01 | 0.003 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.938425e-01 | 0.003 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.938999e-01 | 0.003 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 9.943376e-01 | 0.002 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.943890e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.945122e-01 | 0.002 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.945374e-01 | 0.002 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.946324e-01 | 0.002 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.946485e-01 | 0.002 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 9.946485e-01 | 0.002 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.946485e-01 | 0.002 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.946485e-01 | 0.002 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 9.950398e-01 | 0.002 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 9.950506e-01 | 0.002 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.953052e-01 | 0.002 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 9.953052e-01 | 0.002 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.953052e-01 | 0.002 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 9.953052e-01 | 0.002 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.955908e-01 | 0.002 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 9.958814e-01 | 0.002 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.958814e-01 | 0.002 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.958814e-01 | 0.002 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 9.958814e-01 | 0.002 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.959413e-01 | 0.002 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.961210e-01 | 0.002 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.961414e-01 | 0.002 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.961414e-01 | 0.002 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.963868e-01 | 0.002 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.963868e-01 | 0.002 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.964084e-01 | 0.002 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.967727e-01 | 0.001 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.967727e-01 | 0.001 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.968303e-01 | 0.001 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.968303e-01 | 0.001 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.969257e-01 | 0.001 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.969935e-01 | 0.001 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.970495e-01 | 0.001 | 1 | 0 |
| Purine salvage | R-HSA-74217 | 9.972194e-01 | 0.001 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.975461e-01 | 0.001 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.975607e-01 | 0.001 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.975607e-01 | 0.001 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.975607e-01 | 0.001 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.975656e-01 | 0.001 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.976625e-01 | 0.001 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.978602e-01 | 0.001 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.979020e-01 | 0.001 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.979020e-01 | 0.001 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.981229e-01 | 0.001 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.982872e-01 | 0.001 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.983112e-01 | 0.001 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.983533e-01 | 0.001 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.984772e-01 | 0.001 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.984854e-01 | 0.001 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.985233e-01 | 0.001 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.985555e-01 | 0.001 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.986464e-01 | 0.001 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.986464e-01 | 0.001 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.987329e-01 | 0.001 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.987970e-01 | 0.001 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.988264e-01 | 0.001 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.988885e-01 | 0.000 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.988885e-01 | 0.000 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.990250e-01 | 0.000 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.990549e-01 | 0.000 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.990641e-01 | 0.000 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 9.993080e-01 | 0.000 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.994227e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.994709e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.994709e-01 | 0.000 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.994937e-01 | 0.000 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.995870e-01 | 0.000 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.996193e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.996749e-01 | 0.000 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.996943e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.997122e-01 | 0.000 | 1 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.997371e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.997371e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.997435e-01 | 0.000 | 0 | 0 |
| Digestion | R-HSA-8935690 | 9.997694e-01 | 0.000 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.997732e-01 | 0.000 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.998001e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.998001e-01 | 0.000 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.998147e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.998372e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.998444e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.998463e-01 | 0.000 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.998525e-01 | 0.000 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.998635e-01 | 0.000 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.998635e-01 | 0.000 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.998772e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.998803e-01 | 0.000 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.998803e-01 | 0.000 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.998841e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.998871e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.998958e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999072e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999074e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.999079e-01 | 0.000 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.999079e-01 | 0.000 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.999121e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.999192e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.999192e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.999270e-01 | 0.000 | 0 | 0 |
| Latent infection - Other responses of Mtb to phagocytosis | R-HSA-1222499 | 9.999292e-01 | 0.000 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.999452e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.999455e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.999522e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999632e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999669e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.999678e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999704e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999719e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999800e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.999809e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999853e-01 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.999858e-01 | 0.000 | 1 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999871e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.999887e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999909e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999913e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999915e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999942e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999970e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999977e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999981e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.999984e-01 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.999989e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999991e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999992e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999994e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999996e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999996e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999997e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999997e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.999997e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999999e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999999e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999999e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999999e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999999e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | -0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| M Phase | R-HSA-68886 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.110223e-16 | 15.955 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 6.247225e-13 | 12.204 | 1 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 7.405188e-13 | 12.130 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.297407e-12 | 11.887 | 1 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 3.062328e-12 | 11.514 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 3.750555e-12 | 11.426 | 1 | 0 |
| Cell junction organization | R-HSA-446728 | 2.976164e-11 | 10.526 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 4.633438e-11 | 10.334 | 1 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 8.919410e-11 | 10.050 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.260836e-10 | 9.899 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 1.541578e-10 | 9.812 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.519508e-10 | 9.818 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.797426e-10 | 9.745 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.076865e-10 | 9.683 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 3.523039e-10 | 9.453 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 5.224411e-10 | 9.282 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 5.224411e-10 | 9.282 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 5.525114e-10 | 9.258 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 6.188281e-10 | 9.208 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 1.293175e-09 | 8.888 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 1.293175e-09 | 8.888 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 1.301210e-09 | 8.886 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.392091e-09 | 8.856 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.463297e-09 | 8.835 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.463297e-09 | 8.835 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.534363e-09 | 8.814 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.760726e-09 | 8.754 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.975883e-09 | 8.704 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 2.722957e-09 | 8.565 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 2.804092e-09 | 8.552 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 2.804092e-09 | 8.552 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 3.497660e-09 | 8.456 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 3.554775e-09 | 8.449 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 3.508584e-09 | 8.455 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 4.716619e-09 | 8.326 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 6.018729e-09 | 8.220 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 6.718104e-09 | 8.173 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 7.382724e-09 | 8.132 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 1.036179e-08 | 7.985 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.084478e-08 | 7.965 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.509662e-08 | 7.821 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.976234e-08 | 7.704 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 2.821834e-08 | 7.549 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 2.828557e-08 | 7.548 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 3.661699e-08 | 7.436 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 3.661699e-08 | 7.436 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 3.726403e-08 | 7.429 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 4.224038e-08 | 7.374 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 4.224038e-08 | 7.374 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 4.521762e-08 | 7.345 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 4.835391e-08 | 7.316 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 4.899717e-08 | 7.310 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 5.151156e-08 | 7.288 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 5.604770e-08 | 7.251 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 6.028787e-08 | 7.220 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 7.021054e-08 | 7.154 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 7.021054e-08 | 7.154 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 7.483609e-08 | 7.126 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 7.543846e-08 | 7.122 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 8.319401e-08 | 7.080 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.657981e-08 | 7.015 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.207366e-07 | 6.918 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.207366e-07 | 6.918 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.324797e-07 | 6.878 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.395550e-07 | 6.855 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.657875e-07 | 6.780 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.739739e-07 | 6.760 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 1.756866e-07 | 6.755 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 1.789562e-07 | 6.747 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 2.018860e-07 | 6.695 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 2.215062e-07 | 6.655 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 2.215062e-07 | 6.655 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.535582e-07 | 6.596 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 2.459579e-07 | 6.609 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.784554e-07 | 6.555 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 3.495438e-07 | 6.456 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 3.781172e-07 | 6.422 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 4.957856e-07 | 6.305 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 5.156573e-07 | 6.288 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.119953e-07 | 6.213 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 8.225650e-07 | 6.085 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 8.688551e-07 | 6.061 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 8.725831e-07 | 6.059 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 9.119269e-07 | 6.040 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.546423e-07 | 6.020 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 9.629722e-07 | 6.016 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 1.060615e-06 | 5.974 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 1.150529e-06 | 5.939 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 1.274869e-06 | 5.895 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.243360e-06 | 5.905 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 1.283935e-06 | 5.891 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 1.325183e-06 | 5.878 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.609817e-06 | 5.793 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.715871e-06 | 5.766 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.803358e-06 | 5.744 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.958858e-06 | 5.708 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 1.958858e-06 | 5.708 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 2.057886e-06 | 5.687 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 2.201866e-06 | 5.657 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 2.230139e-06 | 5.652 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 2.282551e-06 | 5.642 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.332907e-06 | 5.632 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 2.340717e-06 | 5.631 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 2.361464e-06 | 5.627 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.832320e-06 | 5.548 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 2.901009e-06 | 5.537 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.771957e-06 | 5.557 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 3.032333e-06 | 5.518 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 3.032333e-06 | 5.518 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 3.788467e-06 | 5.422 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 3.807350e-06 | 5.419 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 3.909775e-06 | 5.408 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 4.210178e-06 | 5.376 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 4.221082e-06 | 5.375 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 4.241177e-06 | 5.373 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 5.403333e-06 | 5.267 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 5.480969e-06 | 5.261 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 5.858739e-06 | 5.232 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 5.910596e-06 | 5.228 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 5.910596e-06 | 5.228 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 5.929145e-06 | 5.227 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 6.264054e-06 | 5.203 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 7.027165e-06 | 5.153 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 7.418239e-06 | 5.130 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 7.744811e-06 | 5.111 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 9.473247e-06 | 5.024 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.070667e-05 | 4.970 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.057887e-05 | 4.976 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 1.039724e-05 | 4.983 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 1.003608e-05 | 4.998 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.070667e-05 | 4.970 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 1.084882e-05 | 4.965 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.107863e-05 | 4.956 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.309910e-05 | 4.883 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 1.362277e-05 | 4.866 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 1.381817e-05 | 4.860 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.538970e-05 | 4.813 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.572747e-05 | 4.803 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.774462e-05 | 4.751 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.774462e-05 | 4.751 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 1.909780e-05 | 4.719 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 2.014462e-05 | 4.696 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 2.014462e-05 | 4.696 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 2.362337e-05 | 4.627 | 1 | 1 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 2.552710e-05 | 4.593 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 2.552710e-05 | 4.593 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.822370e-05 | 4.549 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.822370e-05 | 4.549 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 2.908119e-05 | 4.536 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 3.783821e-05 | 4.422 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 3.981128e-05 | 4.400 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 4.121737e-05 | 4.385 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 4.250625e-05 | 4.372 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 4.316066e-05 | 4.365 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 4.451666e-05 | 4.351 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 4.452441e-05 | 4.351 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 5.190915e-05 | 4.285 | 1 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 5.491060e-05 | 4.260 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 5.617030e-05 | 4.250 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 6.881840e-05 | 4.162 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 7.233818e-05 | 4.141 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 7.864938e-05 | 4.104 | 1 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 8.754824e-05 | 4.058 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 8.329191e-05 | 4.079 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 8.085048e-05 | 4.092 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 8.085048e-05 | 4.092 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 8.833727e-05 | 4.054 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 8.892871e-05 | 4.051 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 8.919982e-05 | 4.050 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 9.057960e-05 | 4.043 | 1 | 0 |
| Kinesins | R-HSA-983189 | 9.224569e-05 | 4.035 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 9.351272e-05 | 4.029 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 9.606717e-05 | 4.017 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 9.606717e-05 | 4.017 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 9.606717e-05 | 4.017 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.056138e-04 | 3.976 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 1.074168e-04 | 3.969 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 1.416656e-04 | 3.849 | 1 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.472798e-04 | 3.832 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.556810e-04 | 3.808 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.556810e-04 | 3.808 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.601598e-04 | 3.795 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.690335e-04 | 3.772 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 1.832977e-04 | 3.737 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 1.690335e-04 | 3.772 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 1.960755e-04 | 3.708 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.071422e-04 | 3.684 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.071422e-04 | 3.684 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.071422e-04 | 3.684 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.071422e-04 | 3.684 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.133844e-04 | 3.671 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 2.283344e-04 | 3.641 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 2.336779e-04 | 3.631 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 2.428005e-04 | 3.615 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 2.482826e-04 | 3.605 | 1 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 2.514138e-04 | 3.600 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 3.013141e-04 | 3.521 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.192278e-04 | 3.496 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 3.249672e-04 | 3.488 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 3.249672e-04 | 3.488 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 3.491190e-04 | 3.457 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 3.804758e-04 | 3.420 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 3.846669e-04 | 3.415 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 4.043253e-04 | 3.393 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 4.624306e-04 | 3.335 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 4.624306e-04 | 3.335 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 4.429832e-04 | 3.354 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 4.557276e-04 | 3.341 | 1 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 4.624306e-04 | 3.335 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 4.785638e-04 | 3.320 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 4.811615e-04 | 3.318 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 4.811615e-04 | 3.318 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 4.936095e-04 | 3.307 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 5.176611e-04 | 3.286 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 5.417839e-04 | 3.266 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 5.539541e-04 | 3.257 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 5.616369e-04 | 3.251 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 5.874320e-04 | 3.231 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 5.874320e-04 | 3.231 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 6.010213e-04 | 3.221 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 6.308311e-04 | 3.200 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 6.308311e-04 | 3.200 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 6.502706e-04 | 3.187 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 6.502706e-04 | 3.187 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 7.177122e-04 | 3.144 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 7.177122e-04 | 3.144 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 7.704301e-04 | 3.113 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 8.070792e-04 | 3.093 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 8.070792e-04 | 3.093 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 8.100007e-04 | 3.092 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 8.133777e-04 | 3.090 | 1 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 8.288352e-04 | 3.082 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.456467e-04 | 3.073 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 8.505481e-04 | 3.070 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 8.818851e-04 | 3.055 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.000427e-03 | 3.000 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 9.265712e-04 | 3.033 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 9.408958e-04 | 3.026 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 9.408958e-04 | 3.026 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.036405e-03 | 2.984 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.052485e-03 | 2.978 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.139931e-03 | 2.943 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.149505e-03 | 2.939 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.160147e-03 | 2.935 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 1.171470e-03 | 2.931 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.218547e-03 | 2.914 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.227635e-03 | 2.911 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.227635e-03 | 2.911 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 1.281947e-03 | 2.892 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.289644e-03 | 2.890 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 1.326837e-03 | 2.877 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.358433e-03 | 2.867 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 1.362600e-03 | 2.866 | 1 | 1 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.389339e-03 | 2.857 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 1.447293e-03 | 2.839 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.451236e-03 | 2.838 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 1.473514e-03 | 2.832 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.520262e-03 | 2.818 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 1.523802e-03 | 2.817 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 1.551402e-03 | 2.809 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.579619e-03 | 2.801 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.693170e-03 | 2.771 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 1.758551e-03 | 2.755 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 1.771768e-03 | 2.752 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 1.800514e-03 | 2.745 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 1.808003e-03 | 2.743 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 1.808003e-03 | 2.743 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 1.830205e-03 | 2.738 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 2.128772e-03 | 2.672 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.128772e-03 | 2.672 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 2.182473e-03 | 2.661 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 2.182473e-03 | 2.661 | 1 | 1 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.014553e-03 | 2.696 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 2.202380e-03 | 2.657 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 1.993089e-03 | 2.700 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 2.245114e-03 | 2.649 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 2.128772e-03 | 2.672 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 2.172583e-03 | 2.663 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 2.208947e-03 | 2.656 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 2.076169e-03 | 2.683 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.975115e-03 | 2.704 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.182473e-03 | 2.661 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 2.415987e-03 | 2.617 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 2.499739e-03 | 2.602 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 2.574050e-03 | 2.589 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.580140e-03 | 2.588 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 2.594641e-03 | 2.586 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 2.594641e-03 | 2.586 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 2.653875e-03 | 2.576 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.704616e-03 | 2.568 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 2.731026e-03 | 2.564 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 2.731026e-03 | 2.564 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 2.837050e-03 | 2.547 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.846598e-03 | 2.546 | 1 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 3.046291e-03 | 2.516 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 3.048973e-03 | 2.516 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 3.048973e-03 | 2.516 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.151370e-03 | 2.502 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.262819e-03 | 2.486 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.262819e-03 | 2.486 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 3.443712e-03 | 2.463 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 3.546986e-03 | 2.450 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 3.699306e-03 | 2.432 | 1 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 3.762856e-03 | 2.424 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 3.762856e-03 | 2.424 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 3.847437e-03 | 2.415 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 3.847437e-03 | 2.415 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 3.847437e-03 | 2.415 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 3.857697e-03 | 2.414 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 3.926480e-03 | 2.406 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 4.078009e-03 | 2.390 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 4.106759e-03 | 2.387 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 4.271016e-03 | 2.369 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 4.282500e-03 | 2.368 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 4.299611e-03 | 2.367 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 4.450304e-03 | 2.352 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 4.540347e-03 | 2.343 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.540347e-03 | 2.343 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 4.540347e-03 | 2.343 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 4.753890e-03 | 2.323 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 4.796253e-03 | 2.319 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 4.821496e-03 | 2.317 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 4.821496e-03 | 2.317 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 4.936798e-03 | 2.307 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 4.936798e-03 | 2.307 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 4.989956e-03 | 2.302 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 4.989956e-03 | 2.302 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 5.041781e-03 | 2.297 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 5.149444e-03 | 2.288 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 5.359146e-03 | 2.271 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 5.880456e-03 | 2.231 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 6.500399e-03 | 2.187 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 5.518100e-03 | 2.258 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 6.713249e-03 | 2.173 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 5.425758e-03 | 2.266 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 6.630830e-03 | 2.178 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 5.685043e-03 | 2.245 | 1 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 6.089995e-03 | 2.215 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 6.170719e-03 | 2.210 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 6.843084e-03 | 2.165 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 6.843084e-03 | 2.165 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 6.843084e-03 | 2.165 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 7.003190e-03 | 2.155 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 7.043464e-03 | 2.152 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 7.073789e-03 | 2.150 | 1 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 7.085043e-03 | 2.150 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 7.085043e-03 | 2.150 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 7.320840e-03 | 2.135 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 7.338290e-03 | 2.134 | 0 | 0 |
| S Phase | R-HSA-69242 | 7.463375e-03 | 2.127 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 7.481780e-03 | 2.126 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 7.481780e-03 | 2.126 | 1 | 1 |
| Calmodulin induced events | R-HSA-111933 | 7.532452e-03 | 2.123 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 7.532452e-03 | 2.123 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 7.592051e-03 | 2.120 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 7.644706e-03 | 2.117 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 7.644706e-03 | 2.117 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 7.733519e-03 | 2.112 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 7.733519e-03 | 2.112 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 7.806684e-03 | 2.108 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 7.806684e-03 | 2.108 | 0 | 0 |
| Protein folding | R-HSA-391251 | 7.837246e-03 | 2.106 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 8.297624e-03 | 2.081 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 8.777266e-03 | 2.057 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 8.992148e-03 | 2.046 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 9.083235e-03 | 2.042 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 9.083235e-03 | 2.042 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 9.083235e-03 | 2.042 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 9.083235e-03 | 2.042 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 9.268523e-03 | 2.033 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 9.351451e-03 | 2.029 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 9.351451e-03 | 2.029 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.936129e-03 | 2.003 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 1.013248e-02 | 1.994 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.071907e-02 | 1.970 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.071907e-02 | 1.970 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 1.115288e-02 | 1.953 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 1.115288e-02 | 1.953 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.141245e-02 | 1.943 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 1.145467e-02 | 1.941 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.152802e-02 | 1.938 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 1.155171e-02 | 1.937 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.155171e-02 | 1.937 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.190987e-02 | 1.924 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.198742e-02 | 1.921 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.201930e-02 | 1.920 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.223634e-02 | 1.912 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 1.260642e-02 | 1.899 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.500923e-02 | 1.824 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.500923e-02 | 1.824 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.500923e-02 | 1.824 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.500923e-02 | 1.824 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.500923e-02 | 1.824 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.500923e-02 | 1.824 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.348600e-02 | 1.870 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.348600e-02 | 1.870 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 1.423230e-02 | 1.847 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 1.324367e-02 | 1.878 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.324367e-02 | 1.878 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 1.528417e-02 | 1.816 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 1.306564e-02 | 1.884 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 1.475387e-02 | 1.831 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 1.539211e-02 | 1.813 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.423230e-02 | 1.847 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 1.528417e-02 | 1.816 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 1.423230e-02 | 1.847 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 1.722727e-02 | 1.764 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 1.528417e-02 | 1.816 | 0 | 0 |
| Translation | R-HSA-72766 | 1.652969e-02 | 1.782 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 1.475387e-02 | 1.831 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.488946e-02 | 1.827 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 1.411246e-02 | 1.850 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 1.413208e-02 | 1.850 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 1.373619e-02 | 1.862 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 1.602927e-02 | 1.795 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.722727e-02 | 1.764 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.730022e-02 | 1.762 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.730022e-02 | 1.762 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.730022e-02 | 1.762 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.730022e-02 | 1.762 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.730022e-02 | 1.762 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 1.730022e-02 | 1.762 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 1.730022e-02 | 1.762 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 1.730022e-02 | 1.762 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.760007e-02 | 1.754 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 1.760007e-02 | 1.754 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 1.760007e-02 | 1.754 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 1.825982e-02 | 1.739 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 1.839038e-02 | 1.735 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.847122e-02 | 1.734 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 1.863126e-02 | 1.730 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.879867e-02 | 1.726 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 1.975549e-02 | 1.704 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 1.975549e-02 | 1.704 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 1.979055e-02 | 1.704 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.004409e-02 | 1.698 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 2.013112e-02 | 1.696 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 2.013112e-02 | 1.696 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.112823e-02 | 1.675 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 2.112823e-02 | 1.675 | 1 | 1 |
| Frs2-mediated activation | R-HSA-170968 | 2.176767e-02 | 1.662 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 2.176767e-02 | 1.662 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 2.187235e-02 | 1.660 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 2.278820e-02 | 1.642 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.278820e-02 | 1.642 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 2.278820e-02 | 1.642 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 2.309154e-02 | 1.637 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 2.319120e-02 | 1.635 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 2.319120e-02 | 1.635 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 2.319120e-02 | 1.635 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 2.319120e-02 | 1.635 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 2.319120e-02 | 1.635 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.394942e-02 | 1.621 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.394942e-02 | 1.621 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 2.530149e-02 | 1.597 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 2.530149e-02 | 1.597 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.574869e-02 | 1.589 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 2.607012e-02 | 1.584 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 2.607012e-02 | 1.584 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 2.607012e-02 | 1.584 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 2.656420e-02 | 1.576 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.658613e-02 | 1.575 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 2.692387e-02 | 1.570 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 2.692387e-02 | 1.570 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 2.692387e-02 | 1.570 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 2.703008e-02 | 1.568 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 2.746438e-02 | 1.561 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 2.749254e-02 | 1.561 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 2.749254e-02 | 1.561 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 2.772479e-02 | 1.557 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 2.772479e-02 | 1.557 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 2.772479e-02 | 1.557 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 2.865407e-02 | 1.543 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 2.902683e-02 | 1.537 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 2.906292e-02 | 1.537 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 2.910047e-02 | 1.536 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 2.915472e-02 | 1.535 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.999015e-02 | 1.523 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 2.999015e-02 | 1.523 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 3.026364e-02 | 1.519 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 3.026364e-02 | 1.519 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 3.062367e-02 | 1.514 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 3.071630e-02 | 1.513 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 3.091537e-02 | 1.510 | 1 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 3.148868e-02 | 1.502 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 3.171863e-02 | 1.499 | 0 | 0 |
| Defective Base Excision Repair Associated with OGG1 | R-HSA-9656249 | 3.180005e-02 | 1.498 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.180005e-02 | 1.498 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 3.259383e-02 | 1.487 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 3.261505e-02 | 1.487 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 3.261505e-02 | 1.487 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 3.279776e-02 | 1.484 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.279776e-02 | 1.484 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 3.279776e-02 | 1.484 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 3.279776e-02 | 1.484 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 3.872476e-02 | 1.412 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 3.872476e-02 | 1.412 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 3.346633e-02 | 1.475 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 4.196440e-02 | 1.377 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 4.196440e-02 | 1.377 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 4.196440e-02 | 1.377 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 4.196440e-02 | 1.377 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 4.678005e-02 | 1.330 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 3.536042e-02 | 1.451 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 4.586339e-02 | 1.339 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 4.343930e-02 | 1.362 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 3.645686e-02 | 1.438 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 4.733067e-02 | 1.325 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 3.915314e-02 | 1.407 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 3.915314e-02 | 1.407 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 4.343930e-02 | 1.362 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 3.915314e-02 | 1.407 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 4.343930e-02 | 1.362 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 4.171980e-02 | 1.380 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.645686e-02 | 1.438 | 1 | 1 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 4.451370e-02 | 1.352 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 4.451370e-02 | 1.352 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 4.150878e-02 | 1.382 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 3.941142e-02 | 1.404 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 4.586339e-02 | 1.339 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 3.868128e-02 | 1.412 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 4.343930e-02 | 1.362 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 3.645686e-02 | 1.438 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 3.872476e-02 | 1.412 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 3.869053e-02 | 1.412 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 4.586339e-02 | 1.339 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 4.038989e-02 | 1.394 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 4.586339e-02 | 1.339 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 3.969100e-02 | 1.401 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 4.365461e-02 | 1.360 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 3.430198e-02 | 1.465 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 3.941142e-02 | 1.404 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 4.733067e-02 | 1.325 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 4.948830e-02 | 1.305 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 4.948830e-02 | 1.305 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 4.948830e-02 | 1.305 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.770989e-02 | 1.321 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 3.464716e-02 | 1.460 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 4.091187e-02 | 1.388 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.467625e-02 | 1.460 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 3.521415e-02 | 1.453 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 4.504429e-02 | 1.346 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 3.346633e-02 | 1.475 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 4.855701e-02 | 1.314 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 4.099000e-02 | 1.387 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 4.971044e-02 | 1.304 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 4.980504e-02 | 1.303 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 5.156883e-02 | 1.288 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 5.156883e-02 | 1.288 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 5.156883e-02 | 1.288 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 5.156883e-02 | 1.288 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 5.156883e-02 | 1.288 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 5.161121e-02 | 1.287 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 5.266544e-02 | 1.278 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 5.288631e-02 | 1.277 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 5.326015e-02 | 1.274 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 5.326015e-02 | 1.274 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 5.326015e-02 | 1.274 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 5.326015e-02 | 1.274 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 5.326015e-02 | 1.274 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 5.326015e-02 | 1.274 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 5.404269e-02 | 1.267 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 5.404269e-02 | 1.267 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 5.404269e-02 | 1.267 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 5.404269e-02 | 1.267 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 5.404269e-02 | 1.267 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 5.447443e-02 | 1.264 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 5.477857e-02 | 1.261 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 5.488568e-02 | 1.261 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 5.488568e-02 | 1.261 | 1 | 1 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 5.491201e-02 | 1.260 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 5.491201e-02 | 1.260 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 5.713652e-02 | 1.243 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 5.817721e-02 | 1.235 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 5.818019e-02 | 1.235 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 5.849220e-02 | 1.233 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 5.863861e-02 | 1.232 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 5.952584e-02 | 1.225 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 5.992699e-02 | 1.222 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 6.029132e-02 | 1.220 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 6.029132e-02 | 1.220 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 6.029132e-02 | 1.220 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 6.029132e-02 | 1.220 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 6.064390e-02 | 1.217 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 6.089465e-02 | 1.215 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.121505e-02 | 1.213 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 6.174011e-02 | 1.209 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 6.226965e-02 | 1.206 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 6.226965e-02 | 1.206 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 6.226965e-02 | 1.206 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 6.226965e-02 | 1.206 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 6.226965e-02 | 1.206 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 6.226965e-02 | 1.206 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 6.226965e-02 | 1.206 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 6.380897e-02 | 1.195 | 0 | 0 |
| PKA activation | R-HSA-163615 | 6.380897e-02 | 1.195 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 6.380897e-02 | 1.195 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 6.380897e-02 | 1.195 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 6.483387e-02 | 1.188 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 6.618948e-02 | 1.179 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 6.618948e-02 | 1.179 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 6.629329e-02 | 1.179 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 6.629329e-02 | 1.179 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 6.629329e-02 | 1.179 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 6.629329e-02 | 1.179 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 6.629329e-02 | 1.179 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 6.629329e-02 | 1.179 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 6.629329e-02 | 1.179 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 6.785167e-02 | 1.168 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 6.858571e-02 | 1.164 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 6.981659e-02 | 1.156 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 7.021664e-02 | 1.154 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 7.057686e-02 | 1.151 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 7.123382e-02 | 1.147 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 7.206321e-02 | 1.142 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 7.234905e-02 | 1.141 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 7.234905e-02 | 1.141 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.234905e-02 | 1.141 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 7.234905e-02 | 1.141 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 7.234905e-02 | 1.141 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 7.284127e-02 | 1.138 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 7.284127e-02 | 1.138 | 1 | 1 |
| Translesion Synthesis by POLH | R-HSA-110320 | 7.346625e-02 | 1.134 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 7.394244e-02 | 1.131 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 7.404385e-02 | 1.131 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 7.540536e-02 | 1.123 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.614069e-02 | 1.118 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 7.642102e-02 | 1.117 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 7.642102e-02 | 1.117 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 7.642102e-02 | 1.117 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 7.843898e-02 | 1.105 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 7.843898e-02 | 1.105 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 7.847339e-02 | 1.105 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 7.847339e-02 | 1.105 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 7.849389e-02 | 1.105 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 7.988370e-02 | 1.098 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 7.988370e-02 | 1.098 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 7.988370e-02 | 1.098 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 7.988370e-02 | 1.098 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 7.999320e-02 | 1.097 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 8.013663e-02 | 1.096 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 8.013663e-02 | 1.096 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 8.013663e-02 | 1.096 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 8.177952e-02 | 1.087 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 8.265289e-02 | 1.083 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 8.265289e-02 | 1.083 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 8.265289e-02 | 1.083 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 8.387307e-02 | 1.076 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 8.522974e-02 | 1.069 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 8.522974e-02 | 1.069 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 8.522974e-02 | 1.069 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 8.629073e-02 | 1.064 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 8.731656e-02 | 1.059 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 8.770551e-02 | 1.057 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 8.798378e-02 | 1.056 | 0 | 0 |
| Defective OGG1 Localization | R-HSA-9657050 | 8.798378e-02 | 1.056 | 0 | 0 |
| Defective OGG1 Substrate Binding | R-HSA-9656255 | 8.798378e-02 | 1.056 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 8.798378e-02 | 1.056 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 8.798378e-02 | 1.056 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 8.839016e-02 | 1.054 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 8.839016e-02 | 1.054 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 8.839016e-02 | 1.054 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 8.839016e-02 | 1.054 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 8.839016e-02 | 1.054 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 9.156569e-02 | 1.038 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 1.682312e-01 | 0.774 | 0 | 0 |
| Defective OGG1 Substrate Processing | R-HSA-9656256 | 1.682312e-01 | 0.774 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.682312e-01 | 0.774 | 0 | 0 |
| Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) | R-HSA-5619043 | 1.682312e-01 | 0.774 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.682312e-01 | 0.774 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.682312e-01 | 0.774 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.065170e-01 | 0.973 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.065170e-01 | 0.973 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 1.065170e-01 | 0.973 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.065170e-01 | 0.973 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.367898e-01 | 0.864 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 1.367898e-01 | 0.864 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.367898e-01 | 0.864 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 1.367898e-01 | 0.864 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 1.005527e-01 | 0.998 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 1.005527e-01 | 0.998 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.005527e-01 | 0.998 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.005527e-01 | 0.998 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 1.686544e-01 | 0.773 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 1.686544e-01 | 0.773 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 1.686544e-01 | 0.773 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 1.686544e-01 | 0.773 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.686544e-01 | 0.773 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.686544e-01 | 0.773 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 1.198426e-01 | 0.921 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.198426e-01 | 0.921 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 1.198426e-01 | 0.921 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.198426e-01 | 0.921 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 1.198426e-01 | 0.921 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 1.006644e-01 | 0.997 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 1.154135e-01 | 0.938 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.154135e-01 | 0.938 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.154135e-01 | 0.938 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 1.154135e-01 | 0.938 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 1.310443e-01 | 0.883 | 1 | 1 |
| Translesion synthesis by POLK | R-HSA-5655862 | 1.310443e-01 | 0.883 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.844695e-01 | 0.734 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.844695e-01 | 0.734 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 1.068647e-01 | 0.971 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.474916e-01 | 0.831 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.474916e-01 | 0.831 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.474916e-01 | 0.831 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 1.646859e-01 | 0.783 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 1.646859e-01 | 0.783 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 1.078593e-01 | 0.967 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 1.464062e-01 | 0.834 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.302264e-01 | 0.885 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.393191e-01 | 0.856 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 9.501306e-02 | 1.022 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 1.056677e-01 | 0.976 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.545048e-01 | 0.811 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 1.473234e-01 | 0.832 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.187551e-01 | 0.925 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 1.187551e-01 | 0.925 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.006644e-01 | 0.997 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 1.310443e-01 | 0.883 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.198426e-01 | 0.921 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 1.006644e-01 | 0.997 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 1.322608e-01 | 0.879 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 1.646859e-01 | 0.783 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 1.006644e-01 | 0.997 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 1.844695e-01 | 0.734 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.068647e-01 | 0.971 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 1.194016e-01 | 0.923 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 9.501306e-02 | 1.022 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 1.170726e-01 | 0.932 | 1 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 1.474916e-01 | 0.831 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.710552e-02 | 1.013 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.608027e-01 | 0.794 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 1.702801e-01 | 0.769 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 1.823096e-01 | 0.739 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 1.399154e-01 | 0.854 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 1.825548e-01 | 0.739 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 9.325667e-02 | 1.030 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 1.420987e-01 | 0.847 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 1.186907e-01 | 0.926 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.686544e-01 | 0.773 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.420987e-01 | 0.847 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.757429e-01 | 0.755 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.011854e-01 | 0.995 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.454768e-01 | 0.837 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 1.823096e-01 | 0.739 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.844695e-01 | 0.734 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 1.158948e-01 | 0.936 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 1.033453e-01 | 0.986 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 1.208962e-01 | 0.918 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 1.586120e-01 | 0.800 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 1.545048e-01 | 0.811 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 1.644139e-01 | 0.784 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.068647e-01 | 0.971 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 1.646859e-01 | 0.783 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 1.603284e-01 | 0.795 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 1.603284e-01 | 0.795 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 1.145485e-01 | 0.941 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 1.144315e-01 | 0.941 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 1.582489e-01 | 0.801 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 1.033453e-01 | 0.986 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 1.144315e-01 | 0.941 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 1.313315e-01 | 0.882 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 1.313315e-01 | 0.882 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 1.208962e-01 | 0.918 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.065170e-01 | 0.973 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 1.686544e-01 | 0.773 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 1.686544e-01 | 0.773 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 1.403655e-01 | 0.853 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 1.154135e-01 | 0.938 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 1.154135e-01 | 0.938 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 1.062765e-01 | 0.974 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 1.158948e-01 | 0.936 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 1.158948e-01 | 0.936 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 1.208962e-01 | 0.918 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 1.209785e-01 | 0.917 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 1.155007e-01 | 0.937 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 1.612394e-01 | 0.793 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 1.005527e-01 | 0.998 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.005527e-01 | 0.998 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 9.795973e-02 | 1.009 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 1.176153e-01 | 0.930 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 1.170944e-01 | 0.931 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.775634e-01 | 0.751 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.259504e-01 | 0.900 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 1.005527e-01 | 0.998 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.198426e-01 | 0.921 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.301748e-01 | 0.885 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 1.348198e-01 | 0.870 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 1.364312e-01 | 0.865 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.185537e-01 | 0.926 | 1 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.686544e-01 | 0.773 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 9.501306e-02 | 1.022 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 1.473234e-01 | 0.832 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.759859e-01 | 0.755 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 1.732270e-01 | 0.761 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 1.226261e-01 | 0.911 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 1.473234e-01 | 0.832 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 1.825548e-01 | 0.739 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 1.820421e-01 | 0.740 | 0 | 0 |
| Diseases of Base Excision Repair | R-HSA-9605308 | 1.686544e-01 | 0.773 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.619610e-01 | 0.791 | 1 | 1 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.115239e-01 | 0.953 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.031152e-01 | 0.987 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 1.186907e-01 | 0.926 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.482903e-01 | 0.829 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.499531e-01 | 0.824 | 1 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 1.686544e-01 | 0.773 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.310443e-01 | 0.883 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 1.068647e-01 | 0.971 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.302264e-01 | 0.885 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.608027e-01 | 0.794 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 1.806657e-01 | 0.743 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.186907e-01 | 0.926 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.154135e-01 | 0.938 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.586120e-01 | 0.800 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.474916e-01 | 0.831 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 1.847936e-01 | 0.733 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 1.850614e-01 | 0.733 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 1.910356e-01 | 0.719 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 1.910356e-01 | 0.719 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 1.911851e-01 | 0.719 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.911851e-01 | 0.719 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 1.911851e-01 | 0.719 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.911851e-01 | 0.719 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 1.911851e-01 | 0.719 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.933533e-01 | 0.714 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 1.940738e-01 | 0.712 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.943672e-01 | 0.711 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 1.988617e-01 | 0.701 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.003671e-01 | 0.698 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 2.010238e-01 | 0.697 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.010238e-01 | 0.697 | 1 | 1 |
| Glycogen synthesis | R-HSA-3322077 | 2.010238e-01 | 0.697 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.015970e-01 | 0.696 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 2.015970e-01 | 0.696 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 2.015970e-01 | 0.696 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 2.015970e-01 | 0.696 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 2.015970e-01 | 0.696 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 2.027090e-01 | 0.693 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 2.027092e-01 | 0.693 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 2.049476e-01 | 0.688 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 2.049476e-01 | 0.688 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 2.070856e-01 | 0.684 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 2.073754e-01 | 0.683 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 2.077346e-01 | 0.682 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 2.077346e-01 | 0.682 | 1 | 1 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 2.081900e-01 | 0.682 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 2.084450e-01 | 0.681 | 0 | 0 |
| Disease | R-HSA-1643685 | 2.130885e-01 | 0.671 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 2.185538e-01 | 0.660 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.200179e-01 | 0.658 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 2.200179e-01 | 0.658 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 2.200179e-01 | 0.658 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.203703e-01 | 0.657 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 2.203703e-01 | 0.657 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 2.228038e-01 | 0.652 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 2.233997e-01 | 0.651 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.233997e-01 | 0.651 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 2.233997e-01 | 0.651 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 2.316052e-01 | 0.635 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 2.316052e-01 | 0.635 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.351814e-01 | 0.629 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 2.351814e-01 | 0.629 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 2.351814e-01 | 0.629 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.351814e-01 | 0.629 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 2.352007e-01 | 0.629 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 2.376095e-01 | 0.624 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 2.394619e-01 | 0.621 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.394619e-01 | 0.621 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 2.394619e-01 | 0.621 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.394619e-01 | 0.621 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 2.400819e-01 | 0.620 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 2.412696e-01 | 0.617 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 2.414220e-01 | 0.617 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.414220e-01 | 0.617 | 0 | 0 |
| Defective SLC26A2 causes chondrodysplasias | R-HSA-3560792 | 2.414220e-01 | 0.617 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.414220e-01 | 0.617 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.414220e-01 | 0.617 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 2.414220e-01 | 0.617 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.414220e-01 | 0.617 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 2.414220e-01 | 0.617 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 2.414220e-01 | 0.617 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.414220e-01 | 0.617 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 2.414220e-01 | 0.617 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.414220e-01 | 0.617 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.414220e-01 | 0.617 | 0 | 0 |
| NTRK3 as a dependence receptor | R-HSA-9603505 | 2.414220e-01 | 0.617 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 2.471747e-01 | 0.607 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 2.526346e-01 | 0.598 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.559373e-01 | 0.592 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 2.559373e-01 | 0.592 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 2.570863e-01 | 0.590 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 2.609389e-01 | 0.583 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 2.609389e-01 | 0.583 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 2.609389e-01 | 0.583 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 2.642705e-01 | 0.578 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 2.678028e-01 | 0.572 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 2.679129e-01 | 0.572 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 2.679129e-01 | 0.572 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 2.679129e-01 | 0.572 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 2.679129e-01 | 0.572 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.690401e-01 | 0.570 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 2.690401e-01 | 0.570 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 2.690401e-01 | 0.570 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 2.690401e-01 | 0.570 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 2.731618e-01 | 0.564 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 2.743671e-01 | 0.562 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 2.743671e-01 | 0.562 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 2.794035e-01 | 0.554 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 2.834128e-01 | 0.548 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 2.834128e-01 | 0.548 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 2.918787e-01 | 0.535 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 2.918787e-01 | 0.535 | 1 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 2.918787e-01 | 0.535 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 2.918787e-01 | 0.535 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 2.930785e-01 | 0.533 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 2.948463e-01 | 0.530 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 2.960929e-01 | 0.529 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 2.991026e-01 | 0.524 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.997574e-01 | 0.523 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.997574e-01 | 0.523 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 3.028651e-01 | 0.519 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 3.028651e-01 | 0.519 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 3.028651e-01 | 0.519 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 3.028651e-01 | 0.519 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 3.028651e-01 | 0.519 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 3.028651e-01 | 0.519 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 3.028651e-01 | 0.519 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 3.028651e-01 | 0.519 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 3.028651e-01 | 0.519 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 3.028651e-01 | 0.519 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.028651e-01 | 0.519 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 3.028651e-01 | 0.519 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 3.033992e-01 | 0.518 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 3.054508e-01 | 0.515 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 3.054508e-01 | 0.515 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 3.059001e-01 | 0.514 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 3.059001e-01 | 0.514 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.081764e-01 | 0.511 | 0 | 0 |
| Defective ALG9 causes CDG-1l | R-HSA-4720454 | 3.081764e-01 | 0.511 | 0 | 0 |
| Interaction between PHLDA1 and AURKA | R-HSA-8854521 | 3.081764e-01 | 0.511 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 3.081764e-01 | 0.511 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 3.081764e-01 | 0.511 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.081764e-01 | 0.511 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 3.081764e-01 | 0.511 | 0 | 0 |
| Interleukin-33 signaling | R-HSA-9014843 | 3.081764e-01 | 0.511 | 0 | 0 |
| tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis | R-HSA-9708296 | 3.081764e-01 | 0.511 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 3.202748e-01 | 0.494 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 3.274160e-01 | 0.485 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 3.274160e-01 | 0.485 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 3.274160e-01 | 0.485 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 3.309262e-01 | 0.480 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.364002e-01 | 0.473 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 3.364002e-01 | 0.473 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 3.364002e-01 | 0.473 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 3.364002e-01 | 0.473 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.364002e-01 | 0.473 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 3.364002e-01 | 0.473 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.364002e-01 | 0.473 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 3.364002e-01 | 0.473 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 3.364002e-01 | 0.473 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 3.390063e-01 | 0.470 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 3.391848e-01 | 0.470 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 3.408903e-01 | 0.467 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 3.432882e-01 | 0.464 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 3.463369e-01 | 0.461 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 3.469982e-01 | 0.460 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 3.552972e-01 | 0.449 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 3.552972e-01 | 0.449 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 3.552972e-01 | 0.449 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 3.615415e-01 | 0.442 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 3.615415e-01 | 0.442 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 3.615415e-01 | 0.442 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 3.615415e-01 | 0.442 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 3.615415e-01 | 0.442 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 3.618606e-01 | 0.441 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 3.631369e-01 | 0.440 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 3.641337e-01 | 0.439 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 3.690601e-01 | 0.433 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 3.690601e-01 | 0.433 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.690601e-01 | 0.433 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.690601e-01 | 0.433 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 3.690601e-01 | 0.433 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 3.690601e-01 | 0.433 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 3.694349e-01 | 0.432 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.694349e-01 | 0.432 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 3.793132e-01 | 0.421 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 3.800811e-01 | 0.420 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 3.821698e-01 | 0.418 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 3.821698e-01 | 0.418 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 3.821698e-01 | 0.418 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 3.821698e-01 | 0.418 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 3.874138e-01 | 0.412 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 3.962764e-01 | 0.402 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 3.993617e-01 | 0.399 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 3.997762e-01 | 0.398 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.017975e-01 | 0.396 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 4.017975e-01 | 0.396 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 4.017975e-01 | 0.396 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 4.017975e-01 | 0.396 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 4.017975e-01 | 0.396 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 4.017975e-01 | 0.396 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 4.017975e-01 | 0.396 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 4.017975e-01 | 0.396 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.046508e-01 | 0.393 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 4.046508e-01 | 0.393 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 4.046508e-01 | 0.393 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 4.116658e-01 | 0.385 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 4.141779e-01 | 0.383 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 4.173000e-01 | 0.380 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 4.173000e-01 | 0.380 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 4.173000e-01 | 0.380 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 4.173000e-01 | 0.380 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 4.210929e-01 | 0.376 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 4.217697e-01 | 0.375 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 4.231408e-01 | 0.374 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 4.245891e-01 | 0.372 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 4.245891e-01 | 0.372 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 4.245891e-01 | 0.372 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.245891e-01 | 0.372 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 4.245891e-01 | 0.372 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 4.245891e-01 | 0.372 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 4.245891e-01 | 0.372 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 4.245891e-01 | 0.372 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 4.245891e-01 | 0.372 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 4.245891e-01 | 0.372 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 4.245891e-01 | 0.372 | 0 | 0 |
| Toxicity of tetanus toxin (tetX) | R-HSA-5250982 | 4.245891e-01 | 0.372 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 4.277886e-01 | 0.369 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 4.289267e-01 | 0.368 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.289267e-01 | 0.368 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 4.314289e-01 | 0.365 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 4.333506e-01 | 0.363 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 4.333506e-01 | 0.363 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 4.358602e-01 | 0.361 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 4.433846e-01 | 0.353 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 4.448709e-01 | 0.352 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 4.528385e-01 | 0.344 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 4.536673e-01 | 0.343 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 4.605739e-01 | 0.337 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 4.639862e-01 | 0.333 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 4.639862e-01 | 0.333 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 4.639862e-01 | 0.333 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 4.652077e-01 | 0.332 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.752339e-01 | 0.323 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 4.752339e-01 | 0.323 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.752339e-01 | 0.323 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 4.752339e-01 | 0.323 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 4.752339e-01 | 0.323 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 4.752339e-01 | 0.323 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 4.752339e-01 | 0.323 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.752339e-01 | 0.323 | 0 | 0 |
| Interleukin-36 pathway | R-HSA-9014826 | 4.752339e-01 | 0.323 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 4.752339e-01 | 0.323 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 4.752339e-01 | 0.323 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 4.763245e-01 | 0.322 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 4.763245e-01 | 0.322 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 4.803838e-01 | 0.318 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 4.831356e-01 | 0.316 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 4.831356e-01 | 0.316 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.831699e-01 | 0.316 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 4.861473e-01 | 0.313 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 4.880368e-01 | 0.312 | 1 | 1 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 4.936213e-01 | 0.307 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 4.936213e-01 | 0.307 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 4.936213e-01 | 0.307 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 4.936213e-01 | 0.307 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 4.936213e-01 | 0.307 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 4.961907e-01 | 0.304 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 4.965654e-01 | 0.304 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 4.986222e-01 | 0.302 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 4.993312e-01 | 0.302 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 5.020716e-01 | 0.299 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 5.026353e-01 | 0.299 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 5.026353e-01 | 0.299 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 5.026353e-01 | 0.299 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 5.050087e-01 | 0.297 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 5.105427e-01 | 0.292 | 1 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.214240e-01 | 0.283 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.214240e-01 | 0.283 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.214240e-01 | 0.283 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 5.214240e-01 | 0.283 | 0 | 0 |
| Loss-of-function mutations in DLD cause MSUD3/DLDD | R-HSA-9907570 | 5.214240e-01 | 0.283 | 0 | 0 |
| Loss-of-function mutations in DBT cause MSUD2 | R-HSA-9865113 | 5.214240e-01 | 0.283 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 5.214240e-01 | 0.283 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 5.214240e-01 | 0.283 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 5.214240e-01 | 0.283 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.214240e-01 | 0.283 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 5.214240e-01 | 0.283 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 5.214240e-01 | 0.283 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 5.214240e-01 | 0.283 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 5.214240e-01 | 0.283 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 5.218128e-01 | 0.282 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 5.218128e-01 | 0.282 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 5.218128e-01 | 0.282 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 5.221949e-01 | 0.282 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 5.221949e-01 | 0.282 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 5.221949e-01 | 0.282 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 5.231020e-01 | 0.281 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 5.235693e-01 | 0.281 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 5.245470e-01 | 0.280 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 5.364456e-01 | 0.270 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 5.374477e-01 | 0.270 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 5.374477e-01 | 0.270 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 5.405493e-01 | 0.267 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 5.437306e-01 | 0.265 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 5.437306e-01 | 0.265 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 5.466951e-01 | 0.262 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 5.472943e-01 | 0.262 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 5.496641e-01 | 0.260 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 5.496641e-01 | 0.260 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 5.496641e-01 | 0.260 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 5.496641e-01 | 0.260 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 5.496641e-01 | 0.260 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 5.544647e-01 | 0.256 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 5.550642e-01 | 0.256 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 5.550642e-01 | 0.256 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 5.550642e-01 | 0.256 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 5.550642e-01 | 0.256 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 5.589434e-01 | 0.253 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 5.589434e-01 | 0.253 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 5.616036e-01 | 0.251 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.635509e-01 | 0.249 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 5.635509e-01 | 0.249 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.635509e-01 | 0.249 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.635509e-01 | 0.249 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.635509e-01 | 0.249 | 0 | 0 |
| Branched-chain ketoacid dehydrogenase kinase deficiency | R-HSA-9912481 | 5.635509e-01 | 0.249 | 0 | 0 |
| H139Hfs13* PPM1K causes a mild variant of MSUD | R-HSA-9912529 | 5.635509e-01 | 0.249 | 0 | 0 |
| Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD | R-HSA-9865125 | 5.635509e-01 | 0.249 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 5.635509e-01 | 0.249 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.635509e-01 | 0.249 | 0 | 0 |
| Lactose synthesis | R-HSA-5653890 | 5.635509e-01 | 0.249 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.635509e-01 | 0.249 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 5.635509e-01 | 0.249 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 5.635509e-01 | 0.249 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 5.635509e-01 | 0.249 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 5.635509e-01 | 0.249 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 5.635509e-01 | 0.249 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 5.650527e-01 | 0.248 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 5.650527e-01 | 0.248 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 5.650527e-01 | 0.248 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 5.650527e-01 | 0.248 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 5.670979e-01 | 0.246 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 5.671562e-01 | 0.246 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 5.760021e-01 | 0.240 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 5.760021e-01 | 0.240 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 5.760021e-01 | 0.240 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 5.760021e-01 | 0.240 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 5.760021e-01 | 0.240 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 5.813152e-01 | 0.236 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 5.816589e-01 | 0.235 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 5.857534e-01 | 0.232 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 5.870027e-01 | 0.231 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 5.953718e-01 | 0.225 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 5.955251e-01 | 0.225 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 6.011951e-01 | 0.221 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 6.011951e-01 | 0.221 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 6.011951e-01 | 0.221 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 6.019718e-01 | 0.220 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 6.019718e-01 | 0.220 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 6.019718e-01 | 0.220 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.019718e-01 | 0.220 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 6.019718e-01 | 0.220 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 6.019718e-01 | 0.220 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 6.019718e-01 | 0.220 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.019718e-01 | 0.220 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 6.019718e-01 | 0.220 | 0 | 0 |
| Cysteine formation from homocysteine | R-HSA-1614603 | 6.019718e-01 | 0.220 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 6.019718e-01 | 0.220 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.019718e-01 | 0.220 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 6.019718e-01 | 0.220 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 6.019718e-01 | 0.220 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 6.039816e-01 | 0.219 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 6.116170e-01 | 0.214 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 6.116170e-01 | 0.214 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 6.116170e-01 | 0.214 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 6.174463e-01 | 0.209 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 6.252157e-01 | 0.204 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 6.252157e-01 | 0.204 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 6.252157e-01 | 0.204 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 6.252157e-01 | 0.204 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 6.252407e-01 | 0.204 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 6.252407e-01 | 0.204 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 6.252407e-01 | 0.204 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 6.252407e-01 | 0.204 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 6.282851e-01 | 0.202 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 6.282851e-01 | 0.202 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 6.282851e-01 | 0.202 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 6.299671e-01 | 0.201 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 6.353197e-01 | 0.197 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.370126e-01 | 0.196 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.370126e-01 | 0.196 | 0 | 0 |
| RSK activation | R-HSA-444257 | 6.370126e-01 | 0.196 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.370126e-01 | 0.196 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.370126e-01 | 0.196 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 6.370126e-01 | 0.196 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 6.370126e-01 | 0.196 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 6.370126e-01 | 0.196 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 6.370126e-01 | 0.196 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 6.370126e-01 | 0.196 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.370126e-01 | 0.196 | 0 | 0 |
| SLC-mediated bile acid transport | R-HSA-9958517 | 6.370126e-01 | 0.196 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 6.370126e-01 | 0.196 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 6.370126e-01 | 0.196 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 6.370126e-01 | 0.196 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 6.370126e-01 | 0.196 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 6.417276e-01 | 0.193 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 6.417895e-01 | 0.193 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 6.439522e-01 | 0.191 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 6.439522e-01 | 0.191 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 6.465379e-01 | 0.189 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 6.469098e-01 | 0.189 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 6.481455e-01 | 0.188 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 6.481455e-01 | 0.188 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 6.481455e-01 | 0.188 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 6.481455e-01 | 0.188 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 6.481455e-01 | 0.188 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 6.481455e-01 | 0.188 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 6.481455e-01 | 0.188 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 6.609991e-01 | 0.180 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 6.620163e-01 | 0.179 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 6.689705e-01 | 0.175 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 6.689705e-01 | 0.175 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.689705e-01 | 0.175 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.689705e-01 | 0.175 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 6.689705e-01 | 0.175 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.689705e-01 | 0.175 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 6.689705e-01 | 0.175 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 6.689705e-01 | 0.175 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 6.699240e-01 | 0.174 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 6.699240e-01 | 0.174 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 6.699240e-01 | 0.174 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 6.794058e-01 | 0.168 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 6.794058e-01 | 0.168 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 6.824721e-01 | 0.166 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 6.905970e-01 | 0.161 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 6.905970e-01 | 0.161 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 6.905970e-01 | 0.161 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 6.905970e-01 | 0.161 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 6.905970e-01 | 0.161 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 6.905970e-01 | 0.161 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 6.905970e-01 | 0.161 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 6.961222e-01 | 0.157 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 6.981164e-01 | 0.156 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 6.981164e-01 | 0.156 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 6.981164e-01 | 0.156 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 6.981164e-01 | 0.156 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 6.981164e-01 | 0.156 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 6.981164e-01 | 0.156 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 6.981164e-01 | 0.156 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 6.981164e-01 | 0.156 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 6.981164e-01 | 0.156 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 6.981164e-01 | 0.156 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 7.041893e-01 | 0.152 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 7.045267e-01 | 0.152 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 7.045267e-01 | 0.152 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 7.045267e-01 | 0.152 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 7.101903e-01 | 0.149 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 7.101903e-01 | 0.149 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 7.101903e-01 | 0.149 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 7.101903e-01 | 0.149 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 7.110100e-01 | 0.148 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 7.183290e-01 | 0.144 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 7.209640e-01 | 0.142 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 7.246978e-01 | 0.140 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.246978e-01 | 0.140 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.246978e-01 | 0.140 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 7.246978e-01 | 0.140 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 7.246978e-01 | 0.140 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 7.246978e-01 | 0.140 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 7.246978e-01 | 0.140 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.246978e-01 | 0.140 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.246978e-01 | 0.140 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 7.246978e-01 | 0.140 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.246978e-01 | 0.140 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 7.275551e-01 | 0.138 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 7.275551e-01 | 0.138 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 7.287338e-01 | 0.137 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 7.287338e-01 | 0.137 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 7.287338e-01 | 0.137 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 7.287338e-01 | 0.137 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 7.316493e-01 | 0.136 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 7.373171e-01 | 0.132 | 1 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 7.376685e-01 | 0.132 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 7.418031e-01 | 0.130 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 7.444911e-01 | 0.128 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 7.462602e-01 | 0.127 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 7.462602e-01 | 0.127 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 7.462602e-01 | 0.127 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.489400e-01 | 0.126 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 7.489400e-01 | 0.126 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 7.489400e-01 | 0.126 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.489400e-01 | 0.126 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 7.489400e-01 | 0.126 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 7.514394e-01 | 0.124 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 7.563789e-01 | 0.121 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 7.563789e-01 | 0.121 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 7.563789e-01 | 0.121 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 7.602006e-01 | 0.119 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 7.602006e-01 | 0.119 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 7.628050e-01 | 0.118 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 7.701935e-01 | 0.113 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 7.709063e-01 | 0.113 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 7.709522e-01 | 0.113 | 0 | 0 |
| Maple Syrup Urine Disease | R-HSA-9865114 | 7.710489e-01 | 0.113 | 0 | 0 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | R-HSA-3656253 | 7.710489e-01 | 0.113 | 0 | 0 |
| Defective EXT2 causes exostoses 2 | R-HSA-3656237 | 7.710489e-01 | 0.113 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 7.710489e-01 | 0.113 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 7.710489e-01 | 0.113 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 7.710489e-01 | 0.113 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 7.710489e-01 | 0.113 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.710489e-01 | 0.113 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 7.710489e-01 | 0.113 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 7.710489e-01 | 0.113 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.710489e-01 | 0.113 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 7.710489e-01 | 0.113 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 7.710489e-01 | 0.113 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 7.710489e-01 | 0.113 | 0 | 0 |
| Estrogen biosynthesis | R-HSA-193144 | 7.710489e-01 | 0.113 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 7.710489e-01 | 0.113 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.710489e-01 | 0.113 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 7.746331e-01 | 0.111 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 7.784051e-01 | 0.109 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 7.784051e-01 | 0.109 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 7.784051e-01 | 0.109 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 7.784051e-01 | 0.109 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.784051e-01 | 0.109 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 7.784051e-01 | 0.109 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 7.784051e-01 | 0.109 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.801966e-01 | 0.108 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 7.812434e-01 | 0.107 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 7.911060e-01 | 0.102 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 7.912120e-01 | 0.102 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 7.912120e-01 | 0.102 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 7.912120e-01 | 0.102 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 7.912120e-01 | 0.102 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 7.912120e-01 | 0.102 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 7.912120e-01 | 0.102 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 7.912120e-01 | 0.102 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 7.912165e-01 | 0.102 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 7.930984e-01 | 0.101 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 7.930984e-01 | 0.101 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 7.930984e-01 | 0.101 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 7.930984e-01 | 0.101 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 7.930984e-01 | 0.101 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 7.949395e-01 | 0.100 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 8.008309e-01 | 0.096 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.069237e-01 | 0.093 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.069237e-01 | 0.093 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 8.069237e-01 | 0.093 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.069237e-01 | 0.093 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.096005e-01 | 0.092 | 0 | 0 |
| BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV | R-HSA-9859138 | 8.096005e-01 | 0.092 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 8.096005e-01 | 0.092 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.096005e-01 | 0.092 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.096005e-01 | 0.092 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.096005e-01 | 0.092 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 8.096005e-01 | 0.092 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 8.096005e-01 | 0.092 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 8.096005e-01 | 0.092 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 8.106256e-01 | 0.091 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 8.199199e-01 | 0.086 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 8.199199e-01 | 0.086 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 8.199199e-01 | 0.086 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 8.199199e-01 | 0.086 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 8.199199e-01 | 0.086 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 8.209587e-01 | 0.086 | 1 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 8.263705e-01 | 0.083 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.263705e-01 | 0.083 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 8.263705e-01 | 0.083 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 8.263705e-01 | 0.083 | 0 | 0 |
| Transport and metabolism of PAPS | R-HSA-174362 | 8.263705e-01 | 0.083 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 8.263705e-01 | 0.083 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 8.282658e-01 | 0.082 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.282658e-01 | 0.082 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 8.321257e-01 | 0.080 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 8.321257e-01 | 0.080 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 8.405256e-01 | 0.075 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 8.416643e-01 | 0.075 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 8.416643e-01 | 0.075 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 8.416643e-01 | 0.075 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 8.416643e-01 | 0.075 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 8.416643e-01 | 0.075 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 8.416643e-01 | 0.075 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.416643e-01 | 0.075 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 8.416643e-01 | 0.075 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 8.419359e-01 | 0.075 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 8.419359e-01 | 0.075 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 8.435794e-01 | 0.074 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 8.435794e-01 | 0.074 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.435794e-01 | 0.074 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 8.435794e-01 | 0.074 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 8.460295e-01 | 0.073 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 8.480983e-01 | 0.072 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 8.540364e-01 | 0.069 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 8.540364e-01 | 0.069 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 8.540364e-01 | 0.069 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 8.543189e-01 | 0.068 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 8.556118e-01 | 0.068 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 8.556118e-01 | 0.068 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 8.556118e-01 | 0.068 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 8.556118e-01 | 0.068 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.556118e-01 | 0.068 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 8.556118e-01 | 0.068 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.556118e-01 | 0.068 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 8.612460e-01 | 0.065 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.639020e-01 | 0.064 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 8.643811e-01 | 0.063 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 8.683314e-01 | 0.061 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 8.683314e-01 | 0.061 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 8.683314e-01 | 0.061 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.683314e-01 | 0.061 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 8.683314e-01 | 0.061 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 8.683314e-01 | 0.061 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 8.683314e-01 | 0.061 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 8.683314e-01 | 0.061 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 8.689681e-01 | 0.061 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 8.713492e-01 | 0.060 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 8.734919e-01 | 0.059 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 8.738018e-01 | 0.059 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 8.738018e-01 | 0.059 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 8.799313e-01 | 0.056 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 8.799313e-01 | 0.056 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 8.799313e-01 | 0.056 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 8.826161e-01 | 0.054 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 8.826161e-01 | 0.054 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 8.826161e-01 | 0.054 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 8.826161e-01 | 0.054 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 8.826161e-01 | 0.054 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 8.849553e-01 | 0.053 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 8.849553e-01 | 0.053 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 8.905098e-01 | 0.050 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 8.905098e-01 | 0.050 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 8.905098e-01 | 0.050 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.905098e-01 | 0.050 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 8.905098e-01 | 0.050 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 8.908575e-01 | 0.050 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 8.908575e-01 | 0.050 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 8.908575e-01 | 0.050 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 8.908575e-01 | 0.050 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 8.908575e-01 | 0.050 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 8.943148e-01 | 0.049 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 8.973615e-01 | 0.047 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 8.985586e-01 | 0.046 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 8.985586e-01 | 0.046 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 8.985586e-01 | 0.046 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 8.985586e-01 | 0.046 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 8.985586e-01 | 0.046 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 9.001569e-01 | 0.046 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 9.001569e-01 | 0.046 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 9.001569e-01 | 0.046 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 9.001569e-01 | 0.046 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 9.001569e-01 | 0.046 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 9.001569e-01 | 0.046 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 9.001569e-01 | 0.046 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 9.001569e-01 | 0.046 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.001569e-01 | 0.046 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.001569e-01 | 0.046 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 9.057506e-01 | 0.043 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.057506e-01 | 0.043 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.069146e-01 | 0.042 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.078362e-01 | 0.042 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 9.089545e-01 | 0.041 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 9.089545e-01 | 0.041 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.089545e-01 | 0.041 | 0 | 0 |
| Abacavir metabolism | R-HSA-2161541 | 9.089545e-01 | 0.041 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 9.089545e-01 | 0.041 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.089545e-01 | 0.041 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.124634e-01 | 0.040 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.124634e-01 | 0.040 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.124634e-01 | 0.040 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 9.135975e-01 | 0.039 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.135975e-01 | 0.039 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 9.141481e-01 | 0.039 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 9.169774e-01 | 0.038 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 9.169774e-01 | 0.038 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 9.169774e-01 | 0.038 | 0 | 0 |
| Androgen biosynthesis | R-HSA-193048 | 9.169774e-01 | 0.038 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 9.186849e-01 | 0.037 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.187256e-01 | 0.037 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 9.187256e-01 | 0.037 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.207664e-01 | 0.036 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 9.242937e-01 | 0.034 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 9.242937e-01 | 0.034 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.242937e-01 | 0.034 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 9.242937e-01 | 0.034 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.242937e-01 | 0.034 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.242937e-01 | 0.034 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.242937e-01 | 0.034 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 9.242937e-01 | 0.034 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.299148e-01 | 0.032 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.300057e-01 | 0.032 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.301022e-01 | 0.031 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.309657e-01 | 0.031 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 9.309657e-01 | 0.031 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 9.309657e-01 | 0.031 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 9.309657e-01 | 0.031 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.309657e-01 | 0.031 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.309657e-01 | 0.031 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.333503e-01 | 0.030 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.350744e-01 | 0.029 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.364967e-01 | 0.028 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.370501e-01 | 0.028 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 9.370501e-01 | 0.028 | 0 | 0 |
| Synthesis of dolichyl-phosphate | R-HSA-446199 | 9.370501e-01 | 0.028 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.370501e-01 | 0.028 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.370501e-01 | 0.028 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.370501e-01 | 0.028 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.397138e-01 | 0.027 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.397937e-01 | 0.027 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 9.425985e-01 | 0.026 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.425985e-01 | 0.026 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.425985e-01 | 0.026 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 9.425985e-01 | 0.026 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 9.425985e-01 | 0.026 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.425985e-01 | 0.026 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.441859e-01 | 0.025 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.441859e-01 | 0.025 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.455591e-01 | 0.024 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.476582e-01 | 0.023 | 0 | 0 |
| Diseases of branched-chain amino acid catabolism | R-HSA-9865118 | 9.476582e-01 | 0.023 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.476582e-01 | 0.023 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.476582e-01 | 0.023 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.476582e-01 | 0.023 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 9.482719e-01 | 0.023 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.491033e-01 | 0.023 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.491033e-01 | 0.023 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.493663e-01 | 0.023 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.520716e-01 | 0.021 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 9.522722e-01 | 0.021 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 9.522722e-01 | 0.021 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.522722e-01 | 0.021 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.556037e-01 | 0.020 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.556710e-01 | 0.020 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 9.564797e-01 | 0.019 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.564797e-01 | 0.019 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.564797e-01 | 0.019 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 9.603165e-01 | 0.018 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.603165e-01 | 0.018 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.621078e-01 | 0.017 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 9.638153e-01 | 0.016 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.638153e-01 | 0.016 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.638153e-01 | 0.016 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.653814e-01 | 0.015 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.670058e-01 | 0.015 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 9.670058e-01 | 0.015 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.673935e-01 | 0.014 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.682649e-01 | 0.014 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.698321e-01 | 0.013 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.698321e-01 | 0.013 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.699151e-01 | 0.013 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 9.725681e-01 | 0.012 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.743562e-01 | 0.011 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.744485e-01 | 0.011 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.749872e-01 | 0.011 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.771932e-01 | 0.010 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.771932e-01 | 0.010 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.771932e-01 | 0.010 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.784538e-01 | 0.009 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.792047e-01 | 0.009 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.792047e-01 | 0.009 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.804066e-01 | 0.009 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.807263e-01 | 0.008 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.807447e-01 | 0.008 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.810389e-01 | 0.008 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.811593e-01 | 0.008 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.822547e-01 | 0.008 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.822547e-01 | 0.008 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.825928e-01 | 0.008 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.827114e-01 | 0.008 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.828350e-01 | 0.008 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.839201e-01 | 0.007 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.839201e-01 | 0.007 | 0 | 0 |
| tRNA processing in the mitochondrion | R-HSA-6785470 | 9.842365e-01 | 0.007 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.842365e-01 | 0.007 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.848333e-01 | 0.007 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 9.851487e-01 | 0.006 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.856272e-01 | 0.006 | 0 | 0 |
| Diseases associated with N-glycosylation of proteins | R-HSA-3781860 | 9.856272e-01 | 0.006 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.861659e-01 | 0.006 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.862859e-01 | 0.006 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.862859e-01 | 0.006 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.862943e-01 | 0.006 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.866036e-01 | 0.006 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.868952e-01 | 0.006 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 9.868952e-01 | 0.006 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.880514e-01 | 0.005 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.883114e-01 | 0.005 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 9.883644e-01 | 0.005 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.888664e-01 | 0.005 | 1 | 1 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.891057e-01 | 0.005 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.891057e-01 | 0.005 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.892117e-01 | 0.005 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.900670e-01 | 0.004 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.900670e-01 | 0.004 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.901248e-01 | 0.004 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.909436e-01 | 0.004 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.909436e-01 | 0.004 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.915251e-01 | 0.004 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.917428e-01 | 0.004 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.917428e-01 | 0.004 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.917428e-01 | 0.004 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.921825e-01 | 0.003 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.921825e-01 | 0.003 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.924716e-01 | 0.003 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.927900e-01 | 0.003 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.929001e-01 | 0.003 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.930346e-01 | 0.003 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.937419e-01 | 0.003 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.942943e-01 | 0.002 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.943481e-01 | 0.002 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.943481e-01 | 0.002 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.947900e-01 | 0.002 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.947980e-01 | 0.002 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.952572e-01 | 0.002 | 0 | 0 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 9.956759e-01 | 0.002 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.956759e-01 | 0.002 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.958078e-01 | 0.002 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.959574e-01 | 0.002 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.964058e-01 | 0.002 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.964214e-01 | 0.002 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.965388e-01 | 0.002 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.968118e-01 | 0.001 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.968118e-01 | 0.001 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.968118e-01 | 0.001 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.970126e-01 | 0.001 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.971798e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.975169e-01 | 0.001 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.977073e-01 | 0.001 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.979362e-01 | 0.001 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.983208e-01 | 0.001 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.984654e-01 | 0.001 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.991336e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.992232e-01 | 0.000 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.992232e-01 | 0.000 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.992540e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.992540e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.993200e-01 | 0.000 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.993200e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.993801e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.994411e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.994449e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.995689e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.996443e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.996757e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.997306e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.997959e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.998288e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.998442e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.998454e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.998921e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.999143e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999510e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999613e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999630e-01 | 0.000 | 1 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999704e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999764e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999793e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.999802e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999856e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999885e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999892e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.999934e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999934e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999940e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999967e-01 | 0.000 | 1 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 9.999969e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999971e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 9.999984e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999987e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999988e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999993e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999994e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999995e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999998e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999999e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
