P38D

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0A2R8Y4L2 S6 Sugiyama HNRNPA1L3 HNRNPA1P48 _______________MSKSEsPKEPEQLRKLFIGGLsFEtT
A0MZ66 S492 Sugiyama SHTN1 KIAA1598 NsEtELERILRRRKVtAEADsssPtGILAtsEsKsMPVLGs
A0MZ66 S494 Sugiyama SHTN1 KIAA1598 EtELERILRRRKVtAEADsssPtGILAtsEsKsMPVLGsVs
A0MZ66 S532 Sugiyama SHTN1 KIAA1598 sVssVTKTALNKKTLEAEFNsPsPPtPEPGEGPRKLEGCTS
A0MZ66 T496 Sugiyama SHTN1 KIAA1598 ELERILRRRKVtAEADsssPtGILAtsEsKsMPVLGsVssV
A0MZ66 T537 Sugiyama SHTN1 KIAA1598 TKTALNKKTLEAEFNsPsPPtPEPGEGPRKLEGCTSSKVTF
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NMY6 S243 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B PHLQKVFDRYKsysPyDMLEsIRKEVKGDLENAFLNLVQRI
O00115 S70 Sugiyama DNASE2 DNASE2A DNL2 QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL
O00151 S90 Sugiyama PDLIM1 CLIM1 CLP36 IKGCTDNLtLtVARsEHKVWsPLVtEEGKRHPYKMNLASEP
O00165 S153 Sugiyama HAX1 HS1BP1 PDSHQPRIFGGVLESDARSEsPQPAPDWGsQRPFHRFDDVW
O00170 S159 Sugiyama AIP XAP2 DALQQNPQPLIFHMEMLKVEsPGtYQQDPWAMTDEEKAKAV
O00232 S335 Sugiyama PSMD12 MRWSTLVEDYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLK
O00418 S359 SIGNOR|ELM|iPTMNet|PSP EEF2K NTKLLQSAKtILRGtEEKCGsPQVRTLsGSRPPLLRPLsEN
O00418 S396 SIGNOR|iPTMNet|PSP EEF2K LsENSGDENMSDVTFDsLPSsPsSATPHSQKLDHLHWPVFS
O00429 S126 Sugiyama DNM1L DLP1 DRP1 EIRQEIENETERISGNNKGVsPEPIHLKIFSPNVVNLTLVD
O00499 S298 Sugiyama BIN1 AMPHL TFtVKAQPsDNAPAKGNKsPsPPDGsPAAtPEIRVNHEPEP
O00499 S303 Sugiyama BIN1 AMPHL AQPsDNAPAKGNKsPsPPDGsPAAtPEIRVNHEPEPAGGAt
O00499 T323 Sugiyama BIN1 AMPHL sPAAtPEIRVNHEPEPAGGAtPGAtLPKsPsQLRKGPPVPP
O14497 S363 Sugiyama ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 AAAAAAASGGAQQRsHHAPMsPGssGGGGQPLARtPQPssP
O14545 S327 Sugiyama TRAFD1 FLN29 DHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQNFLQQAAS
O14545 S480 Sugiyama TRAFD1 FLN29 ATYNQLSRstsGPRPGCQPssPCVPKLsNsDsQDIQGRNRD
O14737 S51 Sugiyama PDCD5 TFAR19 EAKHREAEMRNsILAQVLDQsARARLsNLALVKPEKTKAVE
O14910 S130 Sugiyama LIN7A MALS1 VELI1 ELPKTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLK
O15061 S1181 Sugiyama SYNM DMN KIAA0353 SYN AAsPtGASRSVRHVTLGPGQsPLsREVIFLGPAPACPEAWG
O15067 S1062 Sugiyama PFAS KIAA0361 SYCLPPTFPKAsVPREPGGPsPRVAILREEGSNGDREMADA
O15160 S258 Sugiyama POLR1C POLR1E DITLLEPVEGEAAEELSRCFsPGVIEVQEVQGKKVARVANP
O15264 S27 Sugiyama MAPK13 PRKM13 SAPK4 KGFYKQDVNKTAWELPKTYVsPTHVGSGAyGsVCsAIDKRS
O15264 S278 Sugiyama MAPK13 PRKM13 SAPK4 YIQSLPQtPRKDFTQLFPRAsPQAADLLEKMLELDVDKRLT
O15264 S350 Sugiyama MAPK13 PRKM13 SAPK4 HEKLTVDEWKQHIYKEIVNFsPIARKDSRRRSGMKL_____
O15264 S38 Sugiyama MAPK13 PRKM13 SAPK4 AWELPKTYVsPTHVGSGAyGsVCsAIDKRSGEKVAIKKLSR
O15264 S41 Sugiyama MAPK13 PRKM13 SAPK4 LPKTYVsPTHVGSGAyGsVCsAIDKRSGEKVAIKKLSRPFQ
O15264 T180 Sugiyama MAPK13 PRKM13 SAPK4 EDCELKILDFGLARHADAEMtGyVVtRWYRAPEVILSWMHY
O15264 T265 Sugiyama MAPK13 PRKM13 SAPK4 EFVQKLNDKAAKSYIQSLPQtPRKDFTQLFPRAsPQAADLL
O15264 Y182 Sugiyama MAPK13 PRKM13 SAPK4 CELKILDFGLARHADAEMtGyVVtRWYRAPEVILSWMHYNQ
O15264 Y36 Sugiyama MAPK13 PRKM13 SAPK4 KTAWELPKTYVsPTHVGSGAyGsVCsAIDKRSGEKVAIKKL
O15371 S308 Sugiyama EIF3D EIF3S7 LLTVSETANEPPQDEGNsFNsPRNLAMEAtyINHNFsQQCL
O43237 S194 Sugiyama DYNC1LI2 DNCLI2 LIC2 ERKFVKDFQDyMEPEEGCQGsPQRRGPLtsGsDEENVALPL
O43707 T612 Sugiyama ACTN4 KEAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPK
O43847 S106 Sugiyama NRDC NRD1 sEEEGRRGsLsNAGDPEIVKsPsDPKQYRYIKLQNGLQALL
O43847 S108 Sugiyama NRDC NRD1 EEGRRGsLsNAGDPEIVKsPsDPKQYRYIKLQNGLQALLIS
O43852 S261 Sugiyama CALU RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK
O43852 T65 Sugiyama CALU FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60333 S649 Sugiyama KIF1B KIAA0591 KIAA1448 NHVFRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEK
O60333 T652 Sugiyama KIF1B KIAA0591 KIAA1448 FRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEKQGI
O60361 S107 Sugiyama NME2P1 GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDY
O60361 S110 Sugiyama NME2P1 RGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDYKSC
O60927 T75 Sugiyama PPP1R11 HCGV TCTE5 RRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHR
O75179 S2042 Sugiyama ANKRD17 GTAR KIAA0697 TAPTNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPLD
O75179 S2045 Sugiyama ANKRD17 GTAR KIAA0697 TNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPLDCGs
O75376 S157 Sugiyama NCOR1 KIAA1047 LRASADAKKDPAFGGKHEAPssPIsGQPCGDDQNAsPsKLS
O75391 S158 Sugiyama SPAG7 LKELAQRQEEEAAQQGPVVVsPAsDyKDKYSHLIGKGAAKD
O75410 S276 Sugiyama TACC1 KIAA1103 GtPLPKAsYHFsPEELDENtsPLLGDARFQKsPPDLKETPG
O75533 T223 Sugiyama SF3B1 SAP155 tADQtPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsE
O75533 T227 Sugiyama SF3B1 SAP155 tPGAtPKKLssWDQAEtPGHtPsLRWDEtPGRAKGsEtPGA
O75794 S299 Sugiyama CDC123 C10orf7 D123 AQEQDSPAFRCTNSEVtVQPsPyLsyRLPKDFVDLsTGEDA
O75822 T109 Sugiyama EIF3J EIF3S1 PRO0391 KKRQEEIKKRLEEPEEPKVLtPEEQLADKLRLKKLQEEsDL
O75828 S56 Sugiyama CBR3 SDR21C2 TARDVARGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF
O94776 S435 Sugiyama MTA2 MTA1L1 PID RGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFL
O94826 S91 Sugiyama TOMM70 KIAA0719 TOM70 TOMM70A RGDASGLKRNSERKtPEGRAsPAPGsGHPEGPGAHLDMNsL
O94979 S188 Sugiyama SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334 PEDISCIAWNRQVQHILAsAsPsGRATVWDLRKNEPIIKVS
O95067 S392 Sugiyama CCNB2 KLLKISMIPQLNSKAVKDLAsPLIGRs______________
O95359 S2317 Sugiyama TACC2 MPLRRPKMKKtPEKLDNtPAsPPRsPAEPNDIPIAKGTYTF
O95359 S2321 Sugiyama TACC2 RPKMKKtPEKLDNtPAsPPRsPAEPNDIPIAKGTYTFDIDK
O95365 S549 Sugiyama ZBTB7A FBI1 LRF ZBTB7 ZNF857A ARRNGQEKHFKDEDEDEDVAsPDGLGRLNVAGAGGGGDsGG
O95817 S289 Sugiyama BAG3 BIS sVQGAssREGsPARsstPLHsPsPIRVHtVVDRPQQPMTHR
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338 S319 Sugiyama LDHA PIG19 GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______
P00367 T410 Sugiyama GLUD1 GLUD KSNAPRVKAKIIAEGANGPttPEADKIFLERNIMVIPDLYL
P00558 S393 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA
P00558 T394 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL
P00966 T174 Sugiyama ASS1 ASS FKGRNDLMEyAKQHGIPIPVtPKNPWSMDENLMHIsyEAGI
P00966 T219 Sugiyama ASS1 ASS KNQAPPGLytKtQDPAKAPNtPDILEIEFKKGVPVKVTNVK
P04040 T28 Sugiyama CAT ASDQMQHWKEQRAAQKADVLttGAGNPVGDKLNVItVGPRG
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04083 S170 Sugiyama ANXA1 ANX1 LPC1 RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE
P04083 S34 Sugiyama ANXA1 ANX1 LPC1 IENEEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKA
P04083 S37 Sugiyama ANXA1 ANX1 LPC1 EEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKAIMV
P04181 T39 Sugiyama OAT HSSVASATSVATKKtVQGPPtSDDIFEREyKyGAHNyHPLP
P04406 S210 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 T103 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 sKIKWGDAGAEyVVEstGVFttMEKAGAHLQGGAKRVIIsA
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04637 S33 SIGNOR TP53 P53 PLsQEtFsDLWKLLPENNVLsPLPsQAMDDLMLsPDDIEQW
P04637 S46 SIGNOR TP53 P53 LPENNVLsPLPsQAMDDLMLsPDDIEQWFtEDPGPDEAPRM
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04843 S385 Sugiyama RPN1 IDSLTVKIILPEGAKNIEIDsPyEISRAPDELHYTYLDTFG
P05023 S722 Sugiyama ATP1A1 VEGCQRQGAIVAVTGDGVNDsPALKKADIGVAMGIAGSDVS
P05187 S177 Sugiyama ALPP PLAP RAKKAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVP
P05198 T279 Sugiyama EIF2S1 EIF2A KEKIEEKRGVFNVQMEPKVVtDtDEtELARQMERLERENAE
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05387 S17 Sugiyama RPLP2 D11S2243E RPP2 ____MRyVAsyLLAALGGNssPsAKDIKKILDsVGIEADDD
P05387 S79 Sugiyama RPLP2 D11S2243E RPP2 IGKLAsVPAGGAVAVsAAPGsAAPAAGsAPAAAEEKKDEKK
P05787 S291 Sugiyama KRT8 CYK8 ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P05787 S74 SIGNOR KRT8 CYK8 YGGASGMGGITAVtVNQSLLsPLVLEVDPNIQAVRTQEKEQ
P06733 S14 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA
P06733 S263 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GMDVAASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsF
P06733 S272 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06744 S455 Sugiyama GPI ALMRGKSTEEARKELQAAGKsPEDLERLLPHKVFEGNRPTN
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 S320 Sugiyama LDHB GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______
P07205 S393 Sugiyama PGK2 PGKB GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA
P07205 T394 Sugiyama PGK2 PGKB GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL
P07237 Y94 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07355 S243 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D PHLQKVFDRYKsysPyDMLEsIRKEVKGDLENAFLNLVQCI
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 S168 Sugiyama TUBB TUBB5 OK/SW-cl.56 GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
P07437 S172 Sugiyama TUBB TUBB5 OK/SW-cl.56 ISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSVHQL
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 T166 Sugiyama TUBB TUBB5 OK/SW-cl.56 GMGTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
P07437 T72 Sugiyama TUBB TUBB5 OK/SW-cl.56 NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
P07686 T307 Sugiyama HEXB HCC7 PEFDTPGHTLSWGKGQKDLLtPCySRQNKLDSFGPINPTLN
P07737 S28 Sugiyama PFN1 IDNLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEV
P07737 S30 Sugiyama PFN1 NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07814 S688 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 DIIQLQRRGFFICDQPyEPVsPysCKEAPCVLIyIPDGHtK
P07814 S691 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 QLQRRGFFICDQPyEPVsPysCKEAPCVLIyIPDGHtKEMP
P07858 S216 Sugiyama CTSB CPSB PPCTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSE
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S391 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P07900 S50 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL
P07900 S543 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EPIDEyCVQQLKEFEGKtLVsVTKEGLELPEDEEEKKKQEE
P07900 T317 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07942 S658 Sugiyama LAMB1 PTSSRCGNTIPDDDNQVVsLsPGSRYVVLPRPVCFEKGTNY
P08195 S598 Sugiyama SLC3A2 MDU1 LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08195 S607 Sugiyama SLC3A2 MDU1 ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP
P08238 S383 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S535 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
P08238 T309 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238 T537 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08651 S323 Sugiyama NFIC NFI PssPtsSSRNWTEDMEGGIssPVKKtEMDKsPFNsPsPQDs
P08708 S89 Sugiyama RPS17 RPS17L ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL
P08758 T40 Sugiyama ANXA5 ANX5 ENX2 PP4 DAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTL
P08758 T43 Sugiyama ANXA5 ANX5 ENX2 PP4 tLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTLFGR
P08865 T97 Sugiyama RPSA LAMBR LAMR1 IssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQAAFR
P09234 S17 Sugiyama SNRPC ____MPKFyCDyCDtyLtHDsPsVRKTHCSGRKHKENVKDY
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09651 S6 Sugiyama HNRNPA1 HNRPA1 _______________MsKsEsPKEPEQLRKLFIGGLsFEtT
P09923 S174 Sugiyama ALPI RAKQAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMP
P10809 S225 Sugiyama HSPD1 HSP60 KtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVL
P10809 S453 Sugiyama HSPD1 HSP60 EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK
P10809 S70 Sugiyama HSPD1 HSP60 AVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLKDKY
P10809 T231 Sugiyama HSPD1 HSP60 LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P10809 T455 Sugiyama HSPD1 HSP60 GIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLKIP
P10809 Y227 Sugiyama HSPD1 HSP60 LNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLs
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T38 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P11388 S1247 Sugiyama TOP2A TOP2 MKAEAEKKNKKKIKNENtEGsPQEDGVELEGLKQRLEKKQK
P11388 T1244 Sugiyama TOP2A TOP2 TIEMKAEAEKKNKKKIKNENtEGsPQEDGVELEGLKQRLEK
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P11586 T148 Sugiyama MTHFD1 MTHFC MTHFD tsINAGKLARGDLNDCFIPCtPKGCLELIKETGVPIAGRHA
P12270 S2155 Sugiyama TPR PstPtLVVPHRtDGFAEAIHsPQVAGVPRFRFGPPEDMPQT
P12277 S129 Sugiyama CKB CKBB DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG
P12277 T35 Sugiyama CKB CKBB PAEDEFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDD
P12277 Y39 Sugiyama CKB CKBB EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT
P12429 Y15 Sugiyama ANXA3 ANX3 ______MASIWVGHRGTVRDyPDFsPsVDAEAIQKAIRGIG
P13051 S64 Sugiyama UNG DGU UNG1 UNG15 AAIPAKKAPAGQEEPGtPPssPLsAEQLDRIQRNKAAALLR
P13637 S712 Sugiyama ATP1A3 VEGCQRQGAIVAVTGDGVNDsPALKKADIGVAMGIAGSDVS
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639 S595 Sugiyama EEF2 EF2 PVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGLAE
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 T735 Sugiyama EEF2 EF2 HRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCPEQV
P13798 S304 Sugiyama APEH D3F15S2 D3S48E DNF15S2 YVDLIGGKCELLSDDsLAVssPRLSPDQCRIVYLQYPSLIP
P13804 S192 Sugiyama ETFA sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL
P13807 S645 Sugiyama GYS1 GYS PNEADAAQGyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRN
P13807 S649 Sugiyama GYS1 GYS DAAQGyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRNGPLE
P13807 S723 PSP GYS1 GYS TSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN______
P13807 S727 PSP GYS1 GYS KRNsVDtAtsssLstPsEPLsPtssLGEERN__________
P13807 T278 PSP GYS1 GYS VSQITAIEAQHLLKRKPDIVtPNGLNVKKFsAMHEFQNLHA
P14314 S126 Sugiyama PRKCSH G19P1 yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE
P14314 S442 Sugiyama PRKCSH G19P1 EYVYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSA
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14314 Y465 Sugiyama PRKCSH G19P1 sLGtWGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLC
P14550 S211 Sugiyama AKR1A1 ALDR1 ALR LAQNELIAHCQARGLEVTAysPLGSSDRAWRDPDEPVLLEE
P14618 S37 Sugiyama PKM OIP3 PK2 PK3 PKM2 QLHAAMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRs
P14618 T41 Sugiyama PKM OIP3 PK2 PK3 PKM2 AMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtL
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 S552 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 KEKQDKIyFMAGsSRKEAEssPFVERLLKKGyEVIyLTEPV
P14854 S52 Sugiyama COX6B1 COX6B QNyLDFHRCQKAMTAKGGDIsVCEWyQRVYQsLCPtsWVTD
P14866 S101 Sugiyama HNRNPL HNRPL P/OKcl.14 GAAGGGGGGENyDDPHKtPAsPVVHIRGLIDGVVEADLVEA
P14868 T370 Sugiyama DARS1 DARS PIG40 EALAMLREAGVEMGDEDDLstPNEKLLGHLVKEKyDTDFyI
P15336 T69 Sugiyama ATF2 CREB2 CREBP1 HEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELA
P15336 T71 Sugiyama ATF2 CREB2 CREBP1 MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP
P15531 S125 Sugiyama NME1 NDPKA NM23 RGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDyTsC
P15559 S82 Sugiyama NQO1 DIA4 NMOR1 DPANFQYPAESVLAYKEGHLsPDIVAEQKKLEAADLVIFQF
P16152 S56 Sugiyama CBR1 CBR CRN SDR21C1 TARDVTRGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF
P16278 S434 Sugiyama GLB1 ELNR1 GFVLYRTTLPQDCSNPAPLssPLNGVHDRAyVAVDGIPQGV
P16949 S25 SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama STMN1 C1orf215 LAP18 OP18 DIQVKELEKRAsGQAFELILsPRsKEsVPEFPLsPPKKKDL
P16949 S38 SIGNOR|ELM|iPTMNet|EPSD|PSP|Sugiyama STMN1 C1orf215 LAP18 OP18 QAFELILsPRsKEsVPEFPLsPPKKKDLsLEEIQKKLEAAE
P17174 S93 Sugiyama GOT1 PILGLAEFRsCAsRLALGDDsPALKEKRVGGVQsLGGtGAL
P17544 T51 Sugiyama ATF7 ATFA HEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELA
P17544 T53 Sugiyama ATF7 ATFA MTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASS
P17812 S210 Sugiyama CTPS1 CTPS GEQKTKPTQNSVRELRGLGLsPDLVVCRCSNPLDTSVKEKI
P17812 S575 Sugiyama CTPS1 CTPS LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____
P17980 S376 Sugiyama PSMC3 TBP1 MPNEEARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQC
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 S31 Sugiyama PGAM1 PGAMA CDABP0006 HGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALRDAGyE
P18827 S233 Sugiyama SDC1 SDC FETSGENTAVVAVEPDRRNQsPVDQGAtGAsQGLLDRKEVL
P18850 S104 Sugiyama ATF6 KDIKAEPQPLsPAssSYsVssPRSVDSYSSTQHVPEELDLS
P18850 S94 Sugiyama ATF6 WDINNQICTVKDIKAEPQPLsPAssSYsVssPRSVDSYSST
P21333 S1084 Sugiyama FLNA FLN FLN1 PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV
P21333 S1459 Sugiyama FLNA FLN FLN1 KVPVHDVTDASKVKCsGPGLsPGMVRANLPQsFQVDTSKAG
P21333 S1630 Sugiyama FLNA FLN FLN1 PDVTGRYTILIKYGGDEIPFsPyRVRAVPTGDASKCTVTVS
P21333 S2319 Sugiyama FLNA FLN FLN1 VQEPGDyEVsVKFNEEHIPDsPFVVPVAsPsGDARRLtVss
P21333 S2327 Sugiyama FLNA FLN FLN1 VsVKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKV
P21333 S2329 Sugiyama FLNA FLN FLN1 VKFNEEHIPDsPFVVPVAsPsGDARRLtVssLQEsGLKVNQ
P21333 S2370 Sugiyama FLNA FLN FLN1 PASFAVSLNGAKGAIDAKVHsPsGALEECyVtEIDQDKYAV
P21333 S481 Sugiyama FLNA FLN FLN1 AGVPIPRsPyTVtVGQACNPsACRAVGRGLQPKGVRVKETA
P22234 S27 Sugiyama PAICS ADE2 AIRC PAIS LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK
P22314 T233 Sugiyama UBA1 A1S9T UBE1 GEQPLSAMVSMVTKDNPGVVtCLDEARHGFESGDFVSFSEV
P22392 S122 Sugiyama NME2 NM23B GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDy
P22392 S125 Sugiyama NME2 NM23B RGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDyKSC
P22681 T568 Sugiyama CBL CBL2 RNF55 PDRPysVGAEsRPQRRPLPCtPGDCPSRDKLPPVPSSRLGD
P23396 T242 Sugiyama RPS3 OK/SW-cl.26 PIsEQKGGKPEPPAMPQPVPtA___________________
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23528 S156 Sugiyama CFL1 CFL QANCyEEVKDRCTLAEKLGGsAVIsLEGKPL__________
P23528 S160 Sugiyama CFL1 CFL yEEVKDRCTLAEKLGGsAVIsLEGKPL______________
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P23921 S559 Sugiyama RRM1 RR1 ALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTPTDLW
P24534 S8 Sugiyama EEF1B2 EEF1B EF1B _____________MGFGDLKsPAGLQVLNDyLADKSYIEGY
P25205 T722 Sugiyama MCM3 GDsyDPyDFsDtEEEMPQVHtPKTADsQEtKEsQKVELsES
P25786 S14 Sugiyama PSMA1 HC2 NU PROS30 PSC2 _______MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQGSA
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26038 T465 Sugiyama MSN WQQKAQMVQEDLEKTRAELKtAMstPHVAEPAENEQDEQDE
P26038 T469 Sugiyama MSN AQMVQEDLEKTRAELKtAMstPHVAEPAENEQDEQDENGAE
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26640 S301 Sugiyama VARS1 G7A VARS VARS2 DLPtPPGEKKDVSGPMPDsysPRYVEAAWYPWWEQQGFFKP
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27816 T521 Sugiyama MAP4 GLLKDMsPLsEtEMALGKDVtPPPEtEVVLIKNVCLPPEME
P27816 T571 Sugiyama MAP4 ALKTEAPLAKDGVLtLANNVtPAKDVPPLsEtEAtPVPIKD
P28066 S172 Sugiyama PSMA5 QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK
P28066 S179 Sugiyama PSMA5 sGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSL
P28715 S384 Sugiyama ERCC5 ERCM2 XPG XPGC ENRRQARGRNAPAAVDEGsIsPRtLSAIKRALDDDEDVKVC
P28799 T180 Sugiyama GRN DRVHCCPHGAFCDLVHTRCItPtGTHPLAKKLPAQRTNRAV
P29401 S295 Sugiyama TKT ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI
P29401 T287 Sugiyama TKT AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP
P29401 T442 Sugiyama TKT GEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAA
P29692 S133 Sugiyama EEF1D EF1D NVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPAEDDE
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29966 S101 Sugiyama MARCKS MACS PRKCSL sPsAAEKGEPAAAAAPEAGAsPVEKEAPAEGEAAEPGsPtA
P29966 S26 Sugiyama MARCKS MACS PRKCSL SKTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAs
P29966 S27 Sugiyama MARCKS MACS PRKCSL KTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAsP
P30041 T221 Sugiyama PRDX6 AOP2 KIAA0106 LFPKGVFtKELPSGKKYLRYtPQP_________________
P30041 T44 Sugiyama PRDX6 AOP2 KIAA0106 RFHDFLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKR
P30041 T48 Sugiyama PRDX6 AOP2 KIAA0106 FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL
P30041 T49 Sugiyama PRDX6 AOP2 KIAA0106 LGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKLI
P30043 S82 Sugiyama BLVRB FLR SCAN DKTVAGQDAVIVLLGTRNDLsPTTVMSEGARNIVAAMKAHG
P30043 T199 Sugiyama BLVRB FLR SCAN HDLGHFMLRCLttDEyDGHstyPsHQyQ_____________
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 S157 Sugiyama RPL12 QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P30050 S165 Sugiyama RPL12 GRHPHDIIDDINsGAVECPAs____________________
P30086 S139 Sugiyama PEBP1 PBP PEBP RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE
P30086 T42 Sugiyama PEBP1 PBP PEBP QHPLHVTYAGAAVDELGKVLtPtQVKNRPtsIsWDGLDsGK
P30101 S443 Sugiyama PDIA3 ERP57 ERP60 GRP58 LsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLN
P30281 T283 PSP CCND3 ssPAPKAPRGsssQGPsQtstPtDVtAIHL___________
P31150 S316 Sugiyama GDI1 GDIL OPHN2 RABGDIA XAP4 QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM
P31150 T311 Sugiyama GDI1 GDIL OPHN2 RABGDIA XAP4 VRKAGQVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSD
P31749 T308 Sugiyama AKT1 PKB RAC IKITDFGLCKEGIKDGAtMKtFCGtPEyLAPEVLEDNDyGR
P31751 T309 Sugiyama AKT2 IKITDFGLCKEGISDGATMKtFCGtPEyLAPEVLEDNDyGR
P31937 S88 Sugiyama HIBADH YDVFPDACKEFQDAGEQVVSsPADVAEKADRIITMLPTSIN
P31939 S269 Sugiyama ATIC PURH OK/SW-cl.86 LVKELKEALGIPAAAsFKHVsPAGAAVGIPLsEDEAKVCMV
P31939 S300 Sugiyama ATIC PURH OK/SW-cl.86 sEDEAKVCMVyDLyKTLtPIsAAyARARGADRMssFGDFVA
P31939 T297 Sugiyama ATIC PURH OK/SW-cl.86 IPLsEDEAKVCMVyDLyKTLtPIsAAyARARGADRMssFGD
P31943 S104 Sugiyama HNRNPH1 HNRPH HNRPH1 EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S248 Sugiyama SFN HME1 tLWTADNAGEEGGEAPQEPQs____________________
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P32322 S294 Sugiyama PYCR1 QEQVSPAAIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLA
P32322 S301 Sugiyama PYCR1 AIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGKD__
P32322 S303 Sugiyama PYCR1 KKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGKD____
P33176 S175 Sugiyama KIF5B KNS KNS1 VHEDKNRVPYVKGCTERFVCsPDEVMDtIDEGKSNRHVAVT
P33240 S336 Sugiyama CSTF2 PtPRGLLGDAPNDPRGGtLLsVtGEVEPRGYLGPPHQGPPM
P33991 T854 Sugiyama MCM4 CDC21 AITKDMFEEALRALADDDFLtVtGKtVRLL___________
P33991 T859 Sugiyama MCM4 CDC21 MFEEALRALADDDFLtVtGKtVRLL________________
P33992 S315 Sugiyama MCM5 CDC46 RVLGIQVDTDGSGRSFAGAVsPQEEEEFRRLAALPNVYEVI
P34897 T420 Sugiyama SHMT2 LELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFREDD
P34931 T40 Sugiyama HSPA1L VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P35221 S641 Sugiyama CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35606 T828 Sugiyama COPB2 EEWVKETHADLWPAKQyPLVtPNEERNVMEEGKDFQPSRst
P35611 S355 Sugiyama ADD1 ADDA AGGPDNLVLLNPEKYKAKsRsPGsPVGEGtGsPPKWQIGEQ
P35611 S358 Sugiyama ADD1 ADDA PDNLVLLNPEKYKAKsRsPGsPVGEGtGsPPKWQIGEQEFE
P35998 T193 Sugiyama PSMC2 MSS1 TYSDVGGCKEQIEKLREVVEtPLLHPERFVNLGIEPPKGVL
P36578 S66 Sugiyama RPL4 RPL1 KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR
P37802 S145 Sugiyama TAGLN2 KIAA0120 CDABP0035 VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P38646 S212 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P41091 T109 Sugiyama EIF2S3 EIF2G YKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVRH
P41252 S1047 Sugiyama IARS1 IARS ESHTEFIFTTIKAPLKPYPVsPsDKVLIQEKTQLKGSELEI
P42166 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs
P42167 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS
P42224 S710 Sugiyama STAT1 PMELDGPKGtGyIKtELIsVsEVHPSRLQttDNLLPMsPEE
P42892 S733 Sugiyama ECE1 VWCSVRTPESSHEGLITDPHsPsRFRVIGSLSNSKEFSEHF
P43121 T107 Sugiyama MCAM MUC18 EYEQRLsLQDRGAtLALtQVtPQDERIFLCQGKRPRSQEYR
P46013 S1131 Sugiyama MKI67 tPGPsEEsMtDEKTTKIACKsPPPEsVDtPtstKQWPKRSL
P46013 S2105 Sugiyama MKI67 tPDHTEESttDDKTTKIACKsPPPEsMDtPTstRRRPKtPL
P46013 S308 Sugiyama MKI67 VSRKSRPKsGGsGHAVAEPAsPEQELDQNKGKGRDVEsVQt
P46013 T1139 Sugiyama MKI67 MtDEKTTKIACKsPPPEsVDtPtstKQWPKRSLRKADVEEE
P46013 T1261 Sugiyama MKI67 VAAGKTTKIPCDsPQsDPVDtPtsTKQRPKRSIRKADVEGE
P46013 T2113 Sugiyama MKI67 ttDDKTTKIACKsPPPEsMDtPTstRRRPKtPLGKRDIVEE
P46087 T776 Sugiyama NOP2 NOL1 NSUN1 EKQQLPEQPFEKAAFQKQNDtPKGPQPPtVsPIRsSRPPPA
P46087 T784 Sugiyama NOP2 NOL1 NSUN1 PFEKAAFQKQNDtPKGPQPPtVsPIRsSRPPPAKRKKsQsR
P46108 S41 Sugiyama CRK QEAVALLQGQRHGVFLVRDsstsPGDyVLSVSENSRVSHYI
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46937 S289 Sugiyama YAP1 YAP65 MNQRIsQsAPVKQPPPLAPQsPQGGVMGGsNsNQQQQMRLQ
P46937 T119 Sugiyama YAP1 YAP65 PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP
P47756 S207 Sugiyama CAPZB MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst
P47914 S142 Sugiyama RPL29 KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___
P49006 S119 Sugiyama MARCKSL1 MLP MRP KLsGLsFKRNRKEGGGDssAssPtEEEQEQGEIGACsDEGT
P49321 T390 Sugiyama NASP EAPVLPKDGAVNGPsVVGDQtPIEPQtsIERLtEtKDGsGL
P49327 T1120 Sugiyama FASN FAS ESAPRRQQEQQVPILEKFCFtPHTEEGCLsERAALQEELQL
P49448 T410 Sugiyama GLUD2 GLUDP1 KSNAPRVKAKIIAEGANGPttPEADKIFLERNILVIPDLYL
P49585 S347 Sugiyama PCYT1A CTPCT PCYT1 ERsPsPSFRWPFsGKtsPPCsPANLsRHKAAAyDIsEDEED
P49753 S360 Sugiyama ACOT2 PTE2 PTE2A NRNRIKVTKDGyADIVDVLNsPLEGPDQKSFIPVERAESTF
P49792 T1144 Sugiyama RANBP2 NUP358 GFRRsDDMFTFHGPGKsVFGtPtLETANKNHEtDGGsAHGD
P49792 T1761 Sugiyama RANBP2 NUP358 ATKCIACQCPSKQNQtTAIstPAssEIsKAPKsGFEGMFIR
P49840 Y279 Sugiyama GSK3A LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841 Y216 Sugiyama GSK3B LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49903 T387 Sugiyama SEPHS1 SELD SPS SPS1 IDKPRIIEVAPQVATQNVNPtPGAts_______________
P50395 S316 Sugiyama GDI2 RABGDIB QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM
P50395 T311 Sugiyama GDI2 RABGDIB VEKVGQVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSD
P50502 S181 Sugiyama ST13 AAG2 FAM10A1 HIP SNC6 LQKPNAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA
P50552 T335 Sugiyama VASP tTLPRMKssssVttsEtQPCtPsSSDySDLQRVKQELLEEV
P50895 S296 Sugiyama BCAM LU MSK19 TPAGWVREGDTVQLLCRGDGsPsPEYTLFRLQDEQEEVLNV
P50991 T50 Sugiyama CCT4 CCTD SRB PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI
P50993 S719 Sugiyama ATP1A2 KIAA0778 VEGCQRQGAIVAVTGDGVNDsPALKKADIGIAMGISGSDVS
P52564 S26 Sugiyama MAP2K6 MEK6 MKK6 PRKMK6 SKK3 GKKRNPGLKIPKEAFEQPQtsstPPRDLDsKACISIGNQNF
P52564 S35 Sugiyama MAP2K6 MEK6 MKK6 PRKMK6 SKK3 IPKEAFEQPQtsstPPRDLDsKACISIGNQNFEVKADDLEP
P52564 T25 Sugiyama MAP2K6 MEK6 MKK6 PRKMK6 SKK3 KGKKRNPGLKIPKEAFEQPQtsstPPRDLDsKACISIGNQN
P52565 T160 Sugiyama ARHGDIA GDIA1 DKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYsIKSR
P52701 S292 Sugiyama MSH6 GTBP EGssDEIssGVGDsESEGLNsPVKVARKRKRMVTGNGsLKR
P52948 S1028 Sugiyama NUP98 ADAR2 ALDQRFSRLPsKADtsQEICsPRLPIsAsHssKtRsLVGGL
P52948 S623 Sugiyama NUP98 ADAR2 KNLNNsNLFsPVNRDsENLAsPsEyPENGERFsFLSKPVDE
P53621 S173 Sugiyama COPA ASLDQTVRVWDISGLRKKNLsPGAVEsDVRGITGVDLFGTT
P53634 T458 Sugiyama CTSC CPPI yFRIRRGtDECAIEsIAVAAtPIPKL_______________
P53992 S328 Sugiyama SEC24C KIAA0079 sQPGPPQPLPPKRLDPDAIPsPIQVIEDDRNNRGTEPFVTG
P53999 S118 Sugiyama SUB1 PC4 RPO2TC1 PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________
P54105 T223 Sugiyama CLNS1A CLCI ICLN AGVRtEDsIRDyEDGMEVDttPtVAGQFEDADVDH______
P54646 Y179 Sugiyama PRKAA2 AMPK AMPK2 GLSNMMsDGEFLRtsCGsPNyAAPEVISGRLYAGPEVDIWS
P54652 T39 Sugiyama HSPA2 VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ
P54727 T155 Sugiyama RAD23B SEPAPASAAKQEKPAEKPAEtPVAtsPtAtDstsGDssRSN
P55036 S115 Sugiyama PSMD4 MCB1 LALKHRQGKNHKMRIIAFVGsPVEDNEKDLVKLAKRLKKEK
P55060 T341 Sugiyama CSE1L CAS XPO2 LASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEA
P55209 T62 Sugiyama NAP1L1 NRP MMQNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALK
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P55211 S302 Sugiyama CASP9 MCH6 FFIQACGGEQKDHGFEVAstsPEDEsPGsNPEPDATPFQEG
P55789 S59 Sugiyama GFER ALR HERV1 HPO AGRRDAAASASTPAQAPTsDsPVAEDASRRRPCRACVDFKT
P55795 S104 Sugiyama HNRNPH2 FTP3 HNRPH2 EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK
P55809 S509 Sugiyama OXCT1 OXCT SCOT LWEGLTVDDVQKSTGCDFAVsPKLMPMQQIAN_________
P57740 S11 Sugiyama NUP107 __________MDRsGFGEIssPVIREAEVTRTARKQSAQKR
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 S80 Sugiyama TPI1 TPI IAVAAQNCyKVTNGAFtGEIsPGMIKDCGAtWVVLGHsERR
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60228 S203 Sugiyama EIF3E EIF3S6 INT6 DAAMEDLTRLKETIDNNSVSsPLQSLQQRTWLIHWSLFVFF
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 T106 Sugiyama ACTB WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60866 T9 Sugiyama RPS20 ____________MAFKDtGKtPVEPEVAIHRIRITLTSRNV
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 S32 Sugiyama RPL26 sKNRKRHFNAPsHIRRKIMssPLSKELRQKYNVRSMPIRKD
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61313 S100 Sugiyama RPL15 EC45 TCBAP0781 tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW
P61371 S269 PSP ISL1 QQPNDKTNIQGMtGtPMVAAsPERHDGGLQANPVEVQSYQP
P61604 S64 Sugiyama HSPE1 AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD
P61916 S40 Sugiyama NPC2 HE1 EPVQFKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVT
P61978 S284 Sugiyama HNRNPK HNRPK MPPGRGGRPMPPSRRDyDDMsPRRGPPPPPPGRGGRGGsRA
P61978 S81 Sugiyama HNRNPK HNRPK GGKNIKALRtDyNAsVsVPDssGPERILsISADIETIGEIL
P61981 S38 Sugiyama YWHAG ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P62195 T109 Sugiyama PSMC5 SUG1 VHPEGKFVVDVDKNIDINDVtPNCRVALRNDsytLHKILPN
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S137 Sugiyama RPS14 PRO2640 RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______
P62263 S70 Sugiyama RPS14 PRO2640 KETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGI
P62263 T133 Sugiyama RPS14 PRO2640 QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__
P62263 Y72 Sugiyama RPS14 PRO2640 TICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGITA
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62304 S89 Sugiyama SNRPE KSRKQLGRIMLKGDNITLLQsVsN_________________
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 S43 Sugiyama RPL23A KAKKAVLKGVHSHKKKKIRtsPTFRRPKTLRLRRQPKYPRK
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62917 S138 Sugiyama RPL8 EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 S51 Sugiyama PPIA CYPA KtAENFRALSTGEKGFGYKGsCFHRIIPGFMCQGGDFtRHN
P62942 S9 Sugiyama FKBP1A FKBP1 FKBP12 ____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63241 S75 Sugiyama EIF5A KVHLVGIDIFTGKKyEDICPstHNMDVPNIKRNDFQLIGIQ
P63241 T76 Sugiyama EIF5A VHLVGIDIFTGKKyEDICPstHNMDVPNIKRNDFQLIGIQD
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 T106 Sugiyama ACTG1 ACTG WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 T261 Sugiyama EEF1A1 EEF1A EF1A LENG7 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 S439 Sugiyama TUBA1B SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P78347 S210 Sugiyama GTF2I BAP135 WBSCR6 EPKKHVGGRVMVtDADRsILsPGGsCGPIKVKTEPTEDSGI
P80723 T36 Sugiyama BASP1 NAP22 DEKAKEKDKKAEGAAtEEEGtPKEsEPQAAAEPAEAKEGKE
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P85037 S420 Sugiyama FOXK1 MNF RGVSCFRtPFGPLssRsAPAsPtHPGLMsPRsGGLQtPECL
P85037 S428 Sugiyama FOXK1 MNF PFGPLssRsAPAsPtHPGLMsPRsGGLQtPECLsREGsPIP
P85037 T436 Sugiyama FOXK1 MNF sAPAsPtHPGLMsPRsGGLQtPECLsREGsPIPHDPEFGsK
P98082 T329 Sugiyama DAB2 DOC2 SSFDsLKsPDQKKENssssstPLsNGPLNGDVDyFGQQFDQ
Q00613 S303 PSP HSF1 HSTF1 SIDERPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDt
Q00613 S307 PSP HSF1 HSTF1 RPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDtLLsP
Q00613 S326 PSP HSF1 HSTF1 QsPRVEEAsPGRPssVDtLLsPtALIDsILREsEPAPAsVT
Q00613 S363 Sugiyama HSF1 HSTF1 AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE
Q00613 T367 Sugiyama HSF1 HSTF1 ALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNELSDH
Q01105 S161 Sugiyama SET FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q02952 S286 Sugiyama AKAP12 AKAP250 KEEGEEKQEKEPSKsAEsPtsPVtsETGstFKKFFTQGWAG
Q02952 S483 Sugiyama AKAP12 AKAP250 LVKLKEtCVsGEDPTQGADLsPDEKVLSKPPEGVVSEVEML
Q04637 S1231 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI tEDRDRGRDAVKREAALPPVsPLKAALsEEELEKKsKAIIE
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T261 Sugiyama EEF1A2 EEF1AL STN PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06323 S55 Sugiyama PSME1 IFI5111 KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE
Q07021 T165 Sugiyama C1QBP GC1QBP HABP1 SF2P32 GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD
Q07866 S460 Sugiyama KLC1 KLC KNS2 QKDGTsFGEyGGWyKACKVDsPtVTTtLKNLGALyRRQGKF
Q07960 S51 Sugiyama ARHGAP1 CDC42GAP RHOGAP1 KNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDIARHQ
Q08AD1 S673 Sugiyama CAMSAP2 CAMSAP1L1 KIAA1078 DASKFLQDyDIRTGNTREALsPCPsTVsTKSQPGSSAssss
Q08J23 S743 Sugiyama NSUN2 SAKI TRM4 AstGQPDNDVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGV
Q08J23 S751 Sugiyama NSUN2 SAKI TRM4 DVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGVHPPR____
Q09028 S146 Sugiyama RBBP4 RBAP48 EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE
Q09666 S177 Sugiyama AHNAK PM227 VtAytVDVTGREGAKDIDIssPEFKIKIPRHELtEISNVDV
Q09666 S41 Sugiyama AHNAK PM227 HGLTIAQRDDGVFVQEVtQNsPAARTGVVKEGDQIVGATIy
Q09666 S93 Sugiyama AHNAK PM227 LLNTMGHHTVGLKLHRKGDRsPEPGQtWtREVFssCssEVV
Q09666 T3716 Sugiyama AHNAK PM227 VEGDLKGPEVDIKGPKVDIDtPDINIEGsEGKFKGPKFKIP
Q09666 T4100 Sugiyama AHNAK PM227 VDVNLPKADIDVsGPKVDIDtPDIDIHGPEGKLKGPKFKMP
Q09666 T4564 Sugiyama AHNAK PM227 LEGDLKGPKVDVKGPKVGIDtPDIDIHGPEGKLKGPKFKMP
Q12774 S445 Sugiyama ARHGEF5 TIM ASYLMTQIPGTQTESRAEELsPAALsPsLEPIRCSHQPISL
Q12774 S450 Sugiyama ARHGEF5 TIM TQIPGTQTESRAEELsPAALsPsLEPIRCSHQPISLLGsFL
Q12792 S143 Sugiyama TWF1 PTK9 GTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKINEVQ
Q12888 T1609 SIGNOR TP53BP1 SLEQGNRLREQYGLGPYEAVtPLtKAADIsLDNLVEGKRKR
Q12931 S568 Sugiyama TRAP1 HSP75 HSPC5 ISVETDIVVDHYKEEKFEDRsPAAECLSEKETEELMAWMRN
Q13017 S968 Sugiyama ARHGAP5 RHOGAP5 SYLsDNtRESTHQSEDVFLPsPRDCFPyNNyPDsDDDtEAP
Q13131 Y190 Sugiyama PRKAA1 AMPK1 GLsNMMsDGEFLRtsCGsPNyAAPEVISGRLYAGPEVDIWS
Q13200 S16 Sugiyama PSMD2 TRAP2 _____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA
Q13242 S211 Sugiyama SRSF9 SFRS9 SRP30C GYsRsRSGsRGRDsPyQsRGsPHyFsPFRPy__________
Q13242 S216 Sugiyama SRSF9 SFRS9 SRP30C RSGsRGRDsPyQsRGsPHyFsPFRPy_______________
Q13263 S757 Sugiyama TRIM28 KAP1 RNF96 TIF1B TLDLTLIRARLQEKLsPPyssPQEFAQDVGRMFKQFNKLTE
Q13263 Y755 Sugiyama TRIM28 KAP1 RNF96 TIF1B GGTLDLTLIRARLQEKLsPPyssPQEFAQDVGRMFKQFNKL
Q13283 S231 Sugiyama G3BP1 G3BP QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW
Q13283 S232 Sugiyama G3BP1 G3BP EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA
Q13283 T241 Sugiyama G3BP1 G3BP ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP
Q13409 T95 Sugiyama DYNC1I2 DNCI2 DNCIC2 IVFSEYWVPPPMsPSSKsVStPsEAGsQDsGDGAVGsRTLH
Q13428 T1014 Sugiyama TCOF1 ARssssEsEDEDVIPAtQCLtPGIRTNVVTMPTAHPRIAPK
Q13428 T102 Sugiyama TCOF1 IstsEssEEEEEAEAETAKAtPRLAstNssVLGADLPssMK
Q13442 S19 Sugiyama PDAP1 HASPP28 __MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEEE
Q13451 S13 Sugiyama FKBP5 AIG6 FKBP51 ________MttDEGAKNNEEsPtAtVAEQGEDITsKKDRGV
Q13501 S272 PSP SQSTM1 ORCA OSIL GIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQPssCCsD
Q13501 T269 PSP SQSTM1 ORCA OSIL sPLGIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQPssC
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 S168 Sugiyama TUBB3 TUBB4 GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS
Q13509 S172 Sugiyama TUBB3 TUBB4 ISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSIHQL
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13509 T166 Sugiyama TUBB3 TUBB4 GMGTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT
Q13509 T72 Sugiyama TUBB3 TUBB4 NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF
Q13541 S65 Sugiyama EIF4EBP1 ttPGGtRIIyDRKFLMECRNsPVtKtPPRDLPtIPGVtsPs
Q13561 S202 Sugiyama DCTN2 DCTN50 EATKNSKGGSGGKttGtPPDssLVtyELHsRPEQDKFSQAA
Q13573 S224 Sugiyama SNW1 SKIIP SKIP KDPMEPPRFKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQE
Q13573 S232 Sugiyama SNW1 SKIIP SKIP FKINKKIPRGPPsPPAPVMHsPsRKMTVKEQQEWKIPPCIS
Q13586 S621 Sugiyama STIM1 GOK PsAPPGGsPHLDssRsHsPssPDPDtPsPVGDSRALQASRN
Q13586 T626 Sugiyama STIM1 GOK GGsPHLDssRsHsPssPDPDtPsPVGDSRALQASRNTRIPH
Q13610 S57 Sugiyama PWP1 AEAKEKLQEEGGGsDEEEtGsPsEDGMQsARTQARPREPLE
Q13620 S146 Sugiyama CUL4B KIAA0695 EFVGFDAKMAEEsssssssssPtAATSQQQQLKNKsILISS
Q13884 S87 Sugiyama SNTB1 SNT2B1 SFCRGAGAGHPGAGGAQPPDsPAGVRTAFTDLPEQVPESIS
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q13885 T72 Sugiyama TUBB2A TUBB2 NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q14103 S190 Sugiyama HNRNPD AUF1 HNRPD KRAKAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVES
Q14103 T193 Sugiyama HNRNPD AUF1 HNRPD KAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVESIEL
Q14157 S416 Sugiyama UBAP2L KIAA0144 NICE4 tQsPsLVQYDLKNPsDsAVHsPFtKRQAFtPsstMMEVFLQ
Q14157 S470 Sugiyama UBAP2L KIAA0144 NICE4 PPPssPLPsKstsAPQMsPGssDNQsssPQPAQQKLKQQKK
Q14160 S1448 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL QEDEQPPWAsPsPtsRQsPAsPPPLGGGAPVRTAKAERRHQ
Q14160 S504 Sugiyama SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL MKRSIEGRRsEACPCQPDsGsPLPAEEEKRLsAESGLSEDS
Q14204 S2410 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 GEDEAQRRRKGKEDEGEEAAsPMLQIQRDAATIMQPYFTSN
Q14247 S405 Sugiyama CTTN EMS1 EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA
Q14247 Y421 Sugiyama CTTN EMS1 tPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVsGtE
Q14258 S100 Sugiyama TRIM25 EFP RNF147 ZNF147 DLAREPPADVWtPPARAsAPsPNAQVACDHCLKEAAVKTCL
Q14498 S334 Sugiyama RBM39 HCC1 RNPC2 FELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtT
Q14568 S50 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL
Q14684 T708 Sugiyama RRP1B KIAA0179 LNRNMtAEFKKTDKsILVsPtGPsRVAFDPEQKPLHGVLKt
Q14697 S58 Sugiyama GANAB G2AN KIAA0088 FKtCEEssFCKRQRsIRPGLsPyRALLDSLQLGPDSLTVHL
Q14974 S12 Sugiyama KPNB1 NTF97 _________MELITILEKtVsPDRLELEAAQKFLERAAVEN
Q14980 S1757 Sugiyama NUMA1 NMP22 NUMA ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP
Q15003 S81 Sugiyama NCAPH BRRN BRRN1 CAPH KIAA0074 EKERLQRRRsRVFDLQFstDsPRLLAsPsSRsIDIsATIPK
Q15003 T49 Sugiyama NCAPH BRRN BRRN1 CAPH KIAA0074 PsERVFPMPLPRKAPLNIPGtPVLEDFPQNDDEKERLQRRR
Q15056 T100 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 KFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRK
Q15084 S248 Sugiyama PDIA6 ERP5 P5 TXNDC7 LAsRYGIRGFPtIKIFQKGEsPVDyDGGRTRsDIVsRALDL
Q15154 S861 Sugiyama PCM1 KQLEALMAEHQRRQGLAETAsPVAVSLRSDGSENLCTPQQS
Q15181 S250 Sugiyama PPA1 IOPPP PP LVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDALPPPC
Q15181 T245 Sugiyama PPA1 IOPPP PP DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA
Q15293 T76 Sugiyama RCN1 RCN FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD
Q15365 S189 Sugiyama PCBP1 tLsQsPQGRVMtIPyQPMPAssPVICAGGQDRCsDAAGYPH
Q15545 S201 Sugiyama TAF7 TAF2F TAFII55 WEIIAEDETKEAENQGLDIssPGMsGHRQGHDsLEHDELRE
Q15637 S80 Sugiyama SF1 ZFM1 ZNF162 DLTRKLRtGDLGIPPNPEDRsPsPEPIyNsEGKRLNTREFR
Q15642 T302 Sugiyama TRIP10 CIP4 STOT STP VEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTKRWP
Q15648 S1479 Sugiyama MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2 QNLDsEsEsGSSIAEKsyQNsPssDDGIRPLPEYstEKHKK
Q15648 S1482 Sugiyama MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2 DsEsEsGSSIAEKsyQNsPssDDGIRPLPEYstEKHKKHKK
Q15942 S259 Sugiyama ZYX QSQTQPVsLANtQPRGPPAssPAPAPKFsPVtPKFtPVAsK
Q15942 S267 Sugiyama ZYX LANtQPRGPPAssPAPAPKFsPVtPKFtPVAsKFsPGAPGG
Q15942 T270 Sugiyama ZYX tQPRGPPAssPAPAPKFsPVtPKFtPVAsKFsPGAPGGsGs
Q16204 S244 Sugiyama CCDC6 D10S170 TST1 LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF
Q16576 S145 Sugiyama RBBP7 RBAP46 EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE
Q16595 S158 Sugiyama FXN FRDA X25 GDLGTYVINKQTPNKQIWLSsPSSGPKRYDWTGKNWVYSHD
Q16630 T157 Sugiyama CPSF6 CFIM68 SKKLMDLLPKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQS
Q16643 T346 Sugiyama DBN1 D0S117E RRMAPtPIPtRsPsDsstAstPVAEQIERALDEVTsSQPPP
Q16666 S153 Sugiyama IFI16 IFNGIP1 TKEKAGPKGsKVsEEQtQPPsPAGAGMstAMGRsPsPKTSL
Q2NL82 T490 Sugiyama TSR1 KIAA1401 KMLEKYKQERLEEMFPDEVDtPRDVAARIRFQKYRGLKSFR
Q32MZ4 S16 Sugiyama LRRFIP1 GCF2 TRIP _____MtsPAAAQSREIDCLsPEAQKLAEARLAAKRAARAE
Q53EL6 S94 Sugiyama PDCD4 H731 GDsVsDsGsDALRSGLtVPtsPKGRLLDRRSRSGKGRGLPK
Q53EZ4 S425 Sugiyama CEP55 C10orf3 URCC6 ITEPLVTFQGETENREKVAAsPKsPtAALNEsLVECPKCNI
Q53EZ4 S428 Sugiyama CEP55 C10orf3 URCC6 PLVTFQGETENREKVAAsPKsPtAALNEsLVECPKCNIQYP
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S408 Sugiyama HSP90AB3P HSP90BC EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE
Q58FF7 T410 Sugiyama HSP90AB3P HSP90BC IDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK
Q58FF8 S308 Sugiyama HSP90AB2P HSP90BB YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE
Q58FF8 T310 Sugiyama HSP90AB2P HSP90BB TEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEERK
Q5JSH3 S371 Sugiyama WDR44 RPH11 EEILASVMIKNLDtGEEIPLsLAEEKLPTGINPLTLHIMRR
Q5JSH3 S50 Sugiyama WDR44 RPH11 KVGLSTFKETENTAYKVGNEsPVQELKQDVSKKIIEsIIEE
Q5JSH3 S96 Sugiyama WDR44 RPH11 QLEDDsLDSKGKELsDQAtAsPIVARTDLSNIPGLLAIDQV
Q5R3I4 S362 Sugiyama TTC38 GAHDPQTTQELLTTLRDASEsPGENCQHLLARDVGLPLCQA
Q5SW79 S1529 Sugiyama CEP170 FAM68A KAB KIAA0470 PSAMLPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAV
Q5SW79 T1533 Sugiyama CEP170 FAM68A KAB KIAA0470 LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA
Q5T4S7 S178 Sugiyama UBR4 KIAA0462 KIAA1307 RBAF600 AKLPQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLT
Q5T4S7 S181 Sugiyama UBR4 KIAA0462 KIAA1307 RBAF600 PQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLTSVF
Q5THJ4 S1042 Sugiyama VPS13D KIAA0453 SHKNLsFDIPtGsLRDsRAQsPVsGPNVAHLTDGATLNDRS
Q5UIP0 S2161 Sugiyama RIF1 NNAsPQKLRELDPsLVsANDsPsGMQtRCVWsPLAsPStsI
Q5UIP0 S2163 Sugiyama RIF1 AsPQKLRELDPsLVsANDsPsGMQtRCVWsPLAsPStsILK
Q5VT52 S965 Sugiyama RPRD2 KIAA0460 HSPC099 NsLsQsttGHLSLPQKQyPDsPHPVPHRsLFsPQNtLAAPT
Q5VTE0 T261 Sugiyama EEF1A1P5 EEF1AL3 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q69YN4 S1579 Sugiyama VIRMA KIAA1429 MSTP054 CCSDFDLHSELERsFLsEPssPGRtKTTKGFKLGKHKHETF
Q6IS14 S75 Sugiyama EIF5AL1 KVHLVGIDIFTGKKyEDICPstHNMDVPNIKRNDFQLIGIQ
Q6IS14 T76 Sugiyama EIF5AL1 VHLVGIDIFTGKKyEDICPstHNMDVPNIKRNDFQLIGIQD
Q6JBY9 S68 SIGNOR RCSD1 CAPZIP PCSLPLFPPKVDLGQNGEEKsPPNAsHPPKFKVKssPLIEK
Q6P1L8 S49 Sugiyama MRPL14 MRPL32 RPML32 LSAIQKMTRVRVVDNSALGNsPyHRAPRCIHVYKKNGVGKV
Q6PCE3 S175 Sugiyama PGM2L1 BM32A PFVPYAVQKLKAVAGVMItAsHNRKEDNGYKVYWETGAQIT
Q6PGQ7 S558 Sugiyama BORA C13orf34 KQDHTTQRCWMKTASPFQCSsP___________________
Q6PKG0 S521 Sugiyama LARP1 KIAA0731 LARP NCPEFVPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTL
Q6PKG0 S774 Sugiyama LARP1 KIAA0731 LARP LFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtPQLKDS
Q6PKG0 T526 Sugiyama LARP1 KIAA0731 LARP VPRQHYQKEtEsAPGsPRAVtPVPtKTEEVSNLKTLPKGLs
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6ULP2 S151 Sugiyama AFTPH AFTH PGNLNKVVEQRQNVGTLESFsPGDFRTNMNVVHQNKQLESC
Q6VN20 S365 Sugiyama RANBP10 KIAA1464 DSEVRSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHNTGAD
Q6VN20 S367 Sugiyama RANBP10 KIAA1464 EVRSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHNTGADsP
Q6VN20 S369 Sugiyama RANBP10 KIAA1464 RSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHNTGADsPsC
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71U36 S439 Sugiyama TUBA1A TUBA3 SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q7LBC6 S778 Sugiyama KDM3B C5orf7 JHDM2B JMJD1B KIAA1082 DNPLLKTFsNVFGRHsGGFLssPADFsQENKAPFEAVKRFs
Q7LBC6 S779 Sugiyama KDM3B C5orf7 JHDM2B JMJD1B KIAA1082 NPLLKTFsNVFGRHsGGFLssPADFsQENKAPFEAVKRFsL
Q7Z2K8 S100 Sugiyama GPRIN1 KIAA1893 GAsCSDGPRGsLACPsPtCFsPQEsPsKETLEAHGAsIsGt
Q7Z2K8 T97 Sugiyama GPRIN1 KIAA1893 AGEGAsCSDGPRGsLACPsPtCFsPQEsPsKETLEAHGAsI
Q7Z2W4 T273 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 FFQGsQEFLASASAsAERsCtPsPDQIsHRAsLEDAPVDDL
Q7Z417 S692 Sugiyama NUFIP2 KIAA1321 PIG1 IWNLQKQDPKRIItyNEAMDsPDQ_________________
Q7Z5K2 S221 Sugiyama WAPL FOE KIAA0261 WAPAL AsEIKETNDTWNSQFGKRPEsPsEIsPIKGsVRTGLFEWDN
Q7Z5K2 S226 Sugiyama WAPL FOE KIAA0261 WAPAL ETNDTWNSQFGKRPEsPsEIsPIKGsVRTGLFEWDNDFEDI
Q7Z6Z7 T2889 Sugiyama HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 EAVGDTSAAGSSEQPRAGsstPGDAPPAVAEVQGRSDGsGE
Q86TX2 S298 Sugiyama ACOT1 CTE1 NRNRIKVTKDGyADIVDVLNsPLEGPDQKSFIPVERAESTF
Q86UE4 S146 Sugiyama MTDH AEG1 LYRIC PKPNGRTVEVAEGEAVRtPQsVtAKQPPEIDKKNEKSKKNK
Q86UE4 T143 Sugiyama MTDH AEG1 LYRIC SEKPKPNGRTVEVAEGEAVRtPQsVtAKQPPEIDKKNEKSK
Q86UY5 S353 Sugiyama FAM83A TSGP NPFSGRSAGSHPGTRsVsAssGPCsPAAPHPPPPPRFQPHQ
Q86VP6 S376 Sugiyama CAND1 KIAA0829 TIP120 TIP120A CLDAVVSTRHEMLPEFyKTVsPALISRFKEREENVKADVFH
Q86VQ1 T350 Sugiyama GLCCI1 RRAPLPAHYRssstRsIDTQtPsVQERSSSCSSHSPCVSPF
Q86VS8 S238 Sugiyama HOOK3 AENQVLMERLNQsDsIEDPNsPAGRRHLQLQTQLEQLQEET
Q86W92 S999 Sugiyama PPFIBP1 KIAA1230 INNLTHMLKEDDMFKDFAARsPsAsItDEDsNV________
Q86YP4 S100 Sugiyama GATAD2A DGPVDMRTSHSDMKSERRPPsPDVIVLsDNEQPssPRVNGL
Q86YP4 S114 Sugiyama GATAD2A SERRPPsPDVIVLsDNEQPssPRVNGLttVALKETSTEALM
Q8IV50 S206 Sugiyama LYSMD2 QIKLSTQAAKKLKEESRDEEsPyAtSLyHs___________
Q8IWW6 S240 Sugiyama ARHGAP12 SSSsTEQIRAttPPNQGRPDsPVyANLQELKISQSALPPLP
Q8IWW6 T231 Sugiyama ARHGAP12 QDSEsGDELSSSsTEQIRAttPPNQGRPDsPVyANLQELKI
Q8IX90 S155 Sugiyama SKA3 C13orf3 RAMA1 KDDLsDPPVASSCISEKsPRsPQLsDFGLERYIVSQVLPNP
Q8N1F7 S430 Sugiyama NUP93 KIAA0095 TEDYLWLKLNQVCFDDDGTssPQDRLTLsQFQKQLLEDYGE
Q8N556 S265 Sugiyama AFAP1 AFAP KEAYSGCSGPVDSECPPPPssPVHKAELEKKLssERPssDG
Q8N684 T203 Sugiyama CPSF7 GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP
Q8NBJ5 S612 Sugiyama COLGALT1 GLT25D1 PSEC0241 QKMREQQALSREAKNsDVLQsPLDsAARDEL__________
Q8NBJ5 S616 Sugiyama COLGALT1 GLT25D1 PSEC0241 EQQALSREAKNsDVLQsPLDsAARDEL______________
Q8NBJ7 S44 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 NGQATSMVQLQGGRFLMGtNsPDSRDGDGPVREATVKPFAI
Q8NBJ7 T278 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 IDtADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPP
Q8ND56 S300 Sugiyama LSM14A C19orf13 FAM61A RAP55 RAP55A GRFGIRRDGPMKFEKDFDFEsANAQFNKEEIDREFHNKLKL
Q8NE71 S22 Sugiyama ABCF1 ABC50 PKAPKQQPPEPEWIGDGEstsPsDKVVKKGKKDKKIKKTFF
Q8NEY1 S1000 Sugiyama NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 PsPPALPMSLSAKGQLTNIVsPtAAttPRITRsNsIPTHEA
Q8NEY1 T1002 Sugiyama NAV1 KIAA1151 KIAA1213 POMFIL3 STEERIN1 PPALPMSLSAKGQLTNIVsPtAAttPRITRsNsIPTHEAAF
Q8NEZ2 S18 Sugiyama VPS37A HCRP1 ___MSWLFPLTKsAsssAAGsPGGLTSLQQQKQRLIESLRN
Q8NFI4 S181 Sugiyama ST13P5 FAM10A5 LQKPNAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TB72 S82 Sugiyama PUM2 KIAA0235 PUMH2 MVQRRsGQGFHGNsEVNAILsPRsEsGGLGVsMVEYVLsss
Q8TC07 S675 Sugiyama TBC1D15 TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____
Q8TC07 T689 Sugiyama TBC1D15 SGARNDsPtQIPVssDVCRLtPA__________________
Q8TCS8 T757 Sugiyama PNPT1 PNPASE GRDPADGRMRLSRKVLQsPAtTVVRTLNDRssIVMGEPIsQ
Q8TD19 S868 Sugiyama NEK9 KIAA1995 NEK8 NERCC LQGLKVAsEAPLEHKPQVEAssPRLNPAVtCAGKGtPLtPP
Q8WUF5 S567 Sugiyama PPP1R13L IASPP NKIP1 PPP1R13BL RAI ISRLFHRHGGPGPGGPEPELsPItEGSEARAGPPAPAPPAP
Q8WWM7 S111 Sugiyama ATXN2L A2D A2LG A2LP A2RP PGAAAIGsARGQstGKGPPQsPVFEGVyNNSRMLHFLTAVV
Q8WWM7 S558 Sugiyama ATXN2L A2D A2LG A2LP A2RP KRFQLEELRKFGAQFKLQPsssPENsLDPFPPRILKEEPKG
Q8WWM7 S594 Sugiyama ATXN2L A2D A2LG A2LP A2RP EEPKGKEKEVDGLLtsEPMGsPVssKtEsVsDKEDKPPLAP
Q8WX93 S484 Sugiyama PALLD KIAA0992 CGI-151 VRGAPPLQVQWFRQGsEIQDsPDFRILQKKPRSTAEPEEIC
Q8WXI9 S122 Sugiyama GATAD2B KIAA1150 DEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSsRM
Q8WXI9 S135 Sugiyama GATAD2B KIAA1150 ERGRLtPsPDIIVLsDNEAssPRsSsRMEERLKAANLEMFK
Q8WXI9 T120 Sugiyama GATAD2B KIAA1150 INDEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSs
Q92530 S153 Sugiyama PSMF1 RIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIPP
Q92576 S1614 Sugiyama PHF3 KIAA0244 KRQLQEDQENNLQDNQtsNssPCRsNVGKGNIDGNVsCsEN
Q92598 T795 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 DQDPVVRAQEIKTKIKELNNtCEPVVTQPKPKIEsPKLERt
Q92609 S539 Sugiyama TBC1D5 KIAA0210 KsEsMPVQLNKGLSSKNIsssPsVEsLPGGREFtGsPPssA
Q92615 S664 Sugiyama LARP4B KIAA0217 LARP5 ELRKPSYAEICQRTSKEPPssPLQPQKEQKPNTVGCGKEEK
Q92625 S634 Sugiyama ANKS1A ANKS1 KIAA0229 ODIN KAELKLsRsLsKsDsDLLtCsPtEDAtMGsRsEsLsNCsIG
Q92871 S242 Sugiyama PMM1 PMMH22 PGGNDFEIFADPRTVGHSVVsPQDtVQRCREIFFPETAHEA
Q92879 S179 Sugiyama CELF1 BRUNOL2 CUGBP CUGBP1 NAB50 AMAQTAIKAMHQAQtMEGCssPMVVKFADTQKDKEQKRMAQ
Q92945 S181 Sugiyama KHSRP FUBP2 GRGGEQINKIQQDSGCKVQIsPDsGGLPERsVsLtGAPEsV
Q92973 S111 Sugiyama TNPO1 KPNB2 MIP1 TRN FPNGVTDFIKSECLNNIGDSsPLIRATVGILITTIASKGEL
Q92973 S339 Sugiyama TNPO1 KPNB2 MIP1 TRN SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE
Q92993 T158 PSP KAT5 HTATIP TIP60 SCLQPNHRSTKRKVEVVsPAtPVPSETAPASVFPQNGAARR
Q969R5 S683 Sugiyama L3MBTL2 EPVPGEIIAVRVKEEHLDVAsPDKAssPELPVsVENIKQET
Q96B36 S211 Sugiyama AKT1S1 PRAS40 WGFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAE
Q96B36 S212 Sugiyama AKT1S1 PRAS40 GFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAED
Q96C19 S74 Sugiyama EFHD2 SWS1 ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI
Q96CT7 S207 Sugiyama CCDC124 ENPNMRLsQLKQLLKKEWLRsPDNPMNQRAVPFNAPK____
Q96D15 T72 Sugiyama RCN3 UNQ239/PRO272 FQYDHEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGD
Q96EK9 S184 Sugiyama KTI12 SBBI81 GSAQADVPKELEREEsGAAEsPALVtPDSEKSAKHGsGAFy
Q96HE7 S173 Sugiyama ERO1A ERO1L UNQ434/PRO865 LQWTKHDDSSDNFCEADDIQsPEAEyVDLLLNPERYTGYKG
Q96KB5 T320 Sugiyama PBK TOPK CtNEDPKDRPsAAHIVEALEtDV__________________
Q96L14 S238 Sugiyama CEP170P1 CEP170L KIAA0470L PSAMLPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAV
Q96L14 T242 Sugiyama CEP170P1 CEP170L KIAA0470L LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA
Q96MH2 S76 Sugiyama HEXIM2 L3 EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS
Q96S55 T87 Sugiyama WRNIP1 WHIP PGAKRRRLsEssALKQPAtPtAAEssEGEGEEGDDGGETES
Q96ST3 T161 Sugiyama SIN3A PQVYNDFLDIMKEFKSQsIDtPGVISRVSQLFKGHPDLIMG
Q99733 S53 Sugiyama NAP1L4 NAP2 QNPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQL
Q99733 T51 Sugiyama NAP1L4 NAP2 VMQNPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALK
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BQG0 S11 Sugiyama MYBBP1A P160 __________MEsRDPAQPMsPGEAtQsGARPADRYGLLKH
Q9BQG0 T1161 Sugiyama MYBBP1A P160 TLGVQRPKLEKKDAKEIPsAtQsPIsKKRKKKGFLPETKKR
Q9BRS2 T509 Sugiyama RIOK1 RIO1 QVEERtCsDsEDIGssECsDtDSEEQGDHARPKKHTTDPDI
Q9BTC0 T1469 Sugiyama DIDO1 C20orf158 DATF1 KIAA0333 CADVRRNsVERPAEPVAGAAtPsLVEQQKMLEELNKQIEEQ
Q9BV73 S2229 Sugiyama CEP250 CEP2 CNAP1 QRLQDELELTRRALEKERLHsPGAtsTAELGSRGEQGVQLG
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BVA1 T72 Sugiyama TUBB2B NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF
Q9BXP5 S493 Sugiyama SRRT ARS2 ASR2 VNIKEICWNLQNIRLRECELsPGVNRDLTRRVRNINGITQH
Q9BYG3 S230 Sugiyama NIFK MKI67IP NOPP34 LRKKKKKVsGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVA
Q9BYG3 T234 Sugiyama NIFK MKI67IP NOPP34 KKKVsGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELND
Q9BYG3 T238 Sugiyama NIFK MKI67IP NOPP34 sGtLDtPEKtVDsQGPtPVCtPtFLERRKsQVAELNDDDKD
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BZK7 S451 Sugiyama TBL1XR1 IRA1 TBLR1 RGICIHTLTKHQEPVysVAFsPDGRYLASGSFDKCVHIWNT
Q9C000 S107 PSP NLRP1 CARD7 DEFCAP KIAA0926 NAC NALP1 QEGAGHSPSFPYSPSEPHLGsPSQPTSTAVLMPWIHELPAG
Q9C0C2 S1297 Sugiyama TNKS1BP1 KIAA1741 TAB182 GQADWtPDLGLRNMAPGAVCsPGEsKELGVGQMDWGNNLGL
Q9C0C2 S1385 Sugiyama TNKS1BP1 KIAA1741 TAB182 HGVGGVsQCPEPGLRHNGsLsPGLEARDPLEARELGVGETS
Q9C0C2 S435 Sugiyama TNKS1BP1 KIAA1741 TAB182 DAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAALPQGQG
Q9C0C2 S601 Sugiyama TNKS1BP1 KIAA1741 TAB182 LPLQQAEERyEsQEPLAGQEsPLPLATREAALPILEPVLGQ
Q9C0C2 S672 Sugiyama TNKS1BP1 KIAA1741 TAB182 TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP
Q9C0C2 S712 Sugiyama TNKS1BP1 KIAA1741 TAB182 PPPsGGGARRGAGAELKDtQsPstCsEGLLGWsQKDLQSEF
Q9GZV4 S75 Sugiyama EIF5A2 KVHLVGIDIFTGKKyEDICPstHNMDVPNIKRNDYQLICIQ
Q9GZV4 T76 Sugiyama EIF5A2 VHLVGIDIFTGKKyEDICPstHNMDVPNIKRNDYQLICIQD
Q9H0B6 S445 Sugiyama KLC2 RRDsAPyGEyGsWYKACKVDsPtVNTTLRSLGALYRRQGKL
Q9H0L4 S344 Sugiyama CSTF2T KIAA0689 LPPRGLLGDAPNDPRGGtLLsVtGEVEPRGYLGPPHQGPPM
Q9H2C0 S52 Sugiyama GAN GAN1 KLHL16 AHLVLDGEEIPVQKNILAAAsPYIRTKLNYNPPKDDGSTYK
Q9H3K6 T76 Sugiyama BOLA2 BOLA2A My016; BOLA2B VNACLAEELPHIHAFEQKTLtPDQWARERQK__________
Q9H488 S264 Sugiyama POFUT1 FUT12 KIAA0180 DWKNACAMLKDGTAGSHFMAsPQCVGySRSTAAPLTMTMCL
Q9H4A3 S1261 Sugiyama WNK1 HSN2 KDP KIAA0344 PRKWNK1 GIPTSSLTQVVHSAGRRFIVsPVPEsRLRESKVFPSEITDT
Q9H4G0 S544 Sugiyama EPB41L1 KIAA0338 KLIHRDRDWERERRLPssPAsPsPKGtPEKANERAGLREGs
Q9H501 S198 Sugiyama ESF1 ABTAP C20orf6 HDCMC28P DssLEEKQRTLDsGtSEIVKsPRIECSKTRREMQSVVQLIM
Q9H6F5 S102 Sugiyama CCDC86 CYCLON QGQPEPGAAsPQRQQDLHLEsPQRQPEysPEsPRCQPKPSE
Q9H6F5 S110 Sugiyama CCDC86 CYCLON AsPQRQQDLHLEsPQRQPEysPEsPRCQPKPSEEAPKCsQD
Q9H6F5 S113 Sugiyama CCDC86 CYCLON QRQQDLHLEsPQRQPEysPEsPRCQPKPSEEAPKCsQDQGV
Q9H773 S26 Sugiyama DCTPP1 XTP3TPA CDA03 GEIRGDTGGEDTAAPGRFsFsPEPTLEDIRRLHAEFAAERD
Q9H773 S85 Sugiyama DCTPP1 XTP3TPA CDA03 GELAELFQWKTDGEPGPQGWsPRERAALQEELSDVLIYLVA
Q9H7P9 S1049 Sugiyama PLEKHG2 DFTVSVTTPVPKQEGHLDsEsPTNIPLTKQGGSRDVQGPDP
Q9H7P9 S1261 Sugiyama PLEKHG2 GGSLASHVARLEssDLtPPHsPPPSSRQLLGPNAAALSRYL
Q9H8Y8 T222 Sugiyama GORASP2 GOLPH6 IPTRPFEEGKKIsLPGQMAGtPItPLKDGFTEVQLSSVNPP
Q9H8Y8 T225 Sugiyama GORASP2 GOLPH6 RPFEEGKKIsLPGQMAGtPItPLKDGFTEVQLSSVNPPSLS
Q9HAP6 S115 Sugiyama LIN7B MALS2 VELI2 UNQ3116/PRO10200 ELPKTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLK
Q9HAU0 S930 Sugiyama PLEKHA5 KIAA1686 PEPP2 RRHQQACLREKKKGLNVIGAsDQsPLQsPsNLRDNPFRTTQ
Q9HAU0 S933 Sugiyama PLEKHA5 KIAA1686 PEPP2 QQACLREKKKGLNVIGAsDQsPLQsPsNLRDNPFRTTQTRR
Q9HAU0 S937 Sugiyama PLEKHA5 KIAA1686 PEPP2 LREKKKGLNVIGAsDQsPLQsPsNLRDNPFRTTQTRRRDDK
Q9HC35 S146 Sugiyama EML4 C2orf2 EMAPL4 REKKEEsHsNDQsPQIRAsPsPQPssQPLQIHRQtPEsKNA
Q9HC38 T242 Sugiyama GLOD4 C17orf25 CGI-150 My027 PQKELPDLEDLMKRENQKILtPLVsLDtPGKATVQVVILAD
Q9HC38 T249 Sugiyama GLOD4 C17orf25 CGI-150 My027 LEDLMKRENQKILtPLVsLDtPGKATVQVVILADPDGHEIC
Q9HDC9 S188 Sugiyama APMAP C20orf3 UNQ1869/PRO4305 AYKGLFEVNPWKREVKLLLSsEtPIEGKNMSFVNDLTVTQD
Q9NPI6 S523 Sugiyama DCP1A SMIF APSVFQQTVTRSSDLERKAssPsPLtIGtPEsQRKPSIILS
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQR4 S133 Sugiyama NIT2 CUA002 IHLFDIDVPGKITFQESKTLsPGDsFSTFDTPyCRVGLGIC
Q9NQW6 S323 Sugiyama ANLN ITDAKsCEGQNPELLPKtPIsPLKtGVSKPIVKsTLsQtVP
Q9NQW6 T320 Sugiyama ANLN TTSITDAKsCEGQNPELLPKtPIsPLKtGVSKPIVKsTLsQ
Q9NUP9 S115 Sugiyama LIN7C MALS3 VELI3 ELPKTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLK
Q9NW68 S232 Sugiyama BSDC1 UNQ2494/PRO5781 EQsISEEPGWEEEEEELMGIsPIsPKEAKVPVAKISTFPEG
Q9NW68 S235 Sugiyama BSDC1 UNQ2494/PRO5781 ISEEPGWEEEEEELMGIsPIsPKEAKVPVAKISTFPEGEPG
Q9NWS0 T195 Sugiyama PIH1D1 NOP17 sQQNIRSEQRPRIQELGDLytPAPGRAESGPEKPHLNLWLE
Q9NY27 T173 Sugiyama PPP4R2 SBBI57 VMFPGNsPsytERSNINGPGtPRPLNRPKVsLSAPMTTNGL
Q9NYB0 S203 Sugiyama TERF2IP DRIP5 RAP1 PP8000 RYLKHLRGQEHKyLLGDAPVsPssQKLKRKAEEDPEAADsG
Q9NYF8 S290 Sugiyama BCLAF1 BTF KIAA0164 ERsGsGsVGNGssRysPsQNsPIHHIPsRRsPAKtIAPQNA
Q9NZB2 T991 Sugiyama FAM120A C9orf10 KIAA0183 OSSA PLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKNQ
Q9NZT2 S378 Sugiyama OGFR LERsQGDEAGGHGEDRPEPLsPKEsKKRKLELSRREQPPTE
Q9NZV1 S184 Sugiyama CRIM1 S52 UNQ1886/PRO4330 LKRIEEEKPDCSKARCEVQFsPRCPEDSVLIEGYAPPGECC
Q9P0K7 S281 Sugiyama RAI14 KIAA1334 NORPEG KIsSERSGTPKKRKAPPPPIsPtQLsDVssPRsItstPLsG
Q9P0K7 S290 Sugiyama RAI14 KIAA1334 NORPEG PKKRKAPPPPIsPtQLsDVssPRsItstPLsGKEsVFFAEP
Q9P265 S134 Sugiyama DIP2B KIAA1463 HKEQKMALPMPTKRRSTFVQsPADACtPPDtssAsEDEGsL
Q9UGP4 S421 Sugiyama LIMD1 CKEGPLGWSSDGsLGsVLLDsPssPRVRLPCQPLVPGPELR
Q9UGP4 S423 Sugiyama LIMD1 EGPLGWSSDGsLGsVLLDsPssPRVRLPCQPLVPGPELRPS
Q9UGP4 S424 Sugiyama LIMD1 GPLGWSSDGsLGsVLLDsPssPRVRLPCQPLVPGPELRPSA
Q9UGV2 S361 Sugiyama NDRG3 sPFsRsVtsNQsDGtQESCEsPDVLDRHQTMEVsC______
Q9UHB6 S490 Sugiyama LIMA1 EPLIN SREBP3 PP624 ENEEILERPAQLANAREtPHsPGVEDAPIAKVGVLAAsMEA
Q9UHD1 S110 Sugiyama CHORDC1 CHP1 PKFQEHIIQAPKPVEAIKRPsPDEPMtNLELKISAsLKQAL
Q9UHD1 T116 Sugiyama CHORDC1 CHP1 IIQAPKPVEAIKRPsPDEPMtNLELKISAsLKQALDKLKLs
Q9UHI6 T705 Sugiyama DDX20 DP103 GEMIN3 sEstPVDDRIsLEQPPNGsDtPNPEKyQEsPGIQMKTRLKE
Q9UHL4 S213 Sugiyama DPP7 DPP2 QPP AGLGDSNQFFRDVTADFEGQsPKCTQGVREAFRQIKDLFLQ
Q9UI10 T86 Sugiyama EIF2B4 EIF2BD AAQCQVGPTRELPESGIQLGtPREKVPAGRSKAELRAERRA
Q9UJF2 S663 Sugiyama RASAL2 NGAP ssGLQKIFEDPTDSDLHKLKsPsQDNTDSYFRGKTLLLVQQ
Q9UKS6 S341 Sugiyama PACSIN3 DEVtLtsIVPTRDGTAPPPQsPGsPGtGQDEEWsDEEsPRK
Q9UKS6 S344 Sugiyama PACSIN3 tLtsIVPTRDGTAPPPQsPGsPGtGQDEEWsDEEsPRKAAT
Q9UKV3 S365 Sugiyama ACIN1 ACINUS KIAA0670 EEARKSHLARQQQEKEMKttsPLEEEEREIKssQGLKEKsK
Q9UKX7 S221 Sugiyama NUP50 NPAP60L PRO1146 HGNsGRNsESEsNKVAAEtQsPsLFGstKLQQEStFLFHGN
Q9ULD2 S1264 Sugiyama MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 RsPtssAIPLQsPRNsGsFPsPsIsPR______________
Q9ULD2 S1266 Sugiyama MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 PtssAIPLQsPRNsGsFPsPsIsPR________________
Q9ULD2 S1268 Sugiyama MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 ssAIPLQsPRNsGsFPsPsIsPR__________________
Q9UNE7 S23 Sugiyama STUB1 CHIP PP1131 GKEEKEGGARLGAGGGsPEKsPsAQELKEQGNRLFVGRKYP
Q9UNX3 S32 Sugiyama RPL26L1 RPL26P1 sKNRKRHFNAPSHVRRKIMssPLSKELRQKYNVRSMPIRKD
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UPW0 S223 Sugiyama FOXJ3 KIAA1041 AINTVTNKVTLYNTDQDGsDsPRSSLNNSLSDQSLASVNLN
Q9UQ35 S1103 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sPsLQSKSQTsPKGGRsRsssPVtELAsRsPIRQDRGEFsA
Q9UQ35 S1318 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 VPsMASSWGGPHFsPEHKELsNsPLRENsFGsPLEFRNsGP
Q9UQ35 S1329 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 HFsPEHKELsNsPLRENsFGsPLEFRNsGPLGTEMNtGFss
Q9UQ35 S1404 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sELsPDAVEKAGMssNQsIssPVLDAVPRtPsRERsssAss
Q9UQ35 S2132 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 SRMsCFsRPsMsPtPLDRCRsPGMLEPLGssRtPMsVLQQA
Q9UQ35 S2272 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 tAVNLADsRtPAAAAAMNLAsPRtAVAPsAVNLADPRtPtA
Q9UQ35 S857 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sssPHPKVKsGtPPRQGsItsPQANEQsVtPQRRsCFEssP
Q9UQ35 S994 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sPDtKVKPEtPPRQsHsGsIsPyPKVKAQtPPGPsLsGsKs
Q9UQ35 T1413 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 KAGMssNQsIssPVLDAVPRtPsRERsssAssPEMKDGLPR
Q9UQ35 T866 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sGtPPRQGsItsPQANEQsVtPQRRsCFEssPDPELKsRtP
Q9Y243 T305 Sugiyama AKT3 PKBG IKITDFGLCKEGITDAATMKtFCGtPEyLAPEVLEDNDyGR
Q9Y266 T145 Sugiyama NUDC AENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKLKPNLGN
Q9Y2V2 S41 Sugiyama CARHSP1 LDtPRsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGP
Q9Y2W2 S237 Sugiyama WBP11 NPWBP SIPP1 SNP70 RKVGFALDLPPRRRDEDMLysPELAQRGHDDDVSSTSEDDG
Q9Y2X7 S362 Sugiyama GIT1 TLIIDILSEAKRRQQGKsLssPtDNLELsLRSQSDLDDQHD
Q9Y3E2 S45 Sugiyama BOLA1 CGI-143 GSGAIGPVEAAIRTKLEEALsPEVLELRNESGGHAVPPGSE
Q9Y3E2 S81 Sugiyama BOLA1 CGI-143 PPGSETHFRVAVVssRFEGLsPLQRHRLVHAALAEELGGPV
Q9Y490 S729 Sugiyama TLN1 KIAA1027 TLN CALSTSQLVACTKVVAPtIssPVCQEQLVEAGRLVAKAVEG
Q9Y4E8 S225 Sugiyama USP15 KIAA0529 QGQVLVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPss
Q9Y4E8 S229 Sugiyama USP15 KIAA0529 LVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssLsNN
Q9Y5K6 S542 Sugiyama CD2AP PKEEDSANLKPSELKKDtCysPKPsVyLstPssAsKANTTA
Q9Y5K6 Y548 Sugiyama CD2AP ANLKPSELKKDtCysPKPsVyLstPssAsKANTTAFLtPLE
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y5S9 Y54 Sugiyama RBM8A RBM8 HSPC114 MDS014 KRKGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWI
Q9Y5T5 S552 Sugiyama USP16 MSTP039 TEEVDMKNINMDNDLEVLtssPtRNLNGAYLTEGSNGEVDI
Q9Y6G9 S207 Sugiyama DYNC1LI1 DNCLI1 EQKLIRDFQEyVEPGEDFPAsPQRRNtAsQEDKDDsVVLPL
Q9Y6G9 S516 Sugiyama DYNC1LI1 DNCLI1 HAELDRITRKPVtVsPttPtsPtEGEAs_____________
Q9Y6G9 T513 Sugiyama DYNC1LI1 DNCLI1 LDVHAELDRITRKPVtVsPttPtsPtEGEAs__________
Q9Y6G9 T515 Sugiyama DYNC1LI1 DNCLI1 VHAELDRITRKPVtVsPttPtsPtEGEAs____________
Q9Y6M1 S162 Sugiyama IGF2BP2 IMP2 VICKZ2 GHQFENYsFKISYIPDEEVssPsPPQRAQRGDHSSREQGHA
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Cell Cycle R-HSA-1640170 3.998251e-08 7.398 0 0
Cell Cycle, Mitotic R-HSA-69278 6.148962e-08 7.211 0 0
Chromatin organization R-HSA-4839726 6.541692e-08 7.184 0 0
Chromatin modifying enzymes R-HSA-3247509 2.458967e-07 6.609 0 0
Cellular Senescence R-HSA-2559583 1.518161e-06 5.819 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.620617e-06 5.582 0 0
Regulation of TP53 Activity R-HSA-5633007 4.820316e-06 5.317 0 0
Signal Transduction R-HSA-162582 1.219123e-05 4.914 1 0
G0 and Early G1 R-HSA-1538133 7.436750e-05 4.129 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 9.356492e-05 4.029 0 0
M Phase R-HSA-68886 9.841792e-05 4.007 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.074714e-04 3.969 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.142832e-04 3.942 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 1.357363e-04 3.867 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.472865e-04 3.832 0 0
Repression of WNT target genes R-HSA-4641265 1.704490e-04 3.768 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.696636e-04 3.770 0 0
Mitotic Prometaphase R-HSA-68877 2.081366e-04 3.682 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 2.367389e-04 3.626 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 2.743216e-04 3.562 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.646739e-04 3.577 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.710279e-04 3.567 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.693447e-04 3.570 1 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 2.778292e-04 3.556 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.085544e-04 3.511 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 3.085544e-04 3.511 0 0
NRAGE signals death through JNK R-HSA-193648 3.084295e-04 3.511 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 3.474276e-04 3.459 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.998286e-04 3.398 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 3.998286e-04 3.398 0 0
Nuclear Envelope Breakdown R-HSA-2980766 3.785220e-04 3.422 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.839328e-04 3.416 0 0
Signaling by NTRKs R-HSA-166520 3.889334e-04 3.410 1 0
Vpr-mediated nuclear import of PICs R-HSA-180910 4.000449e-04 3.398 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 4.387697e-04 3.358 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 5.275988e-04 3.278 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 5.275988e-04 3.278 0 0
Nuclear Receptor transcription pathway R-HSA-383280 6.328703e-04 3.199 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 6.752889e-04 3.171 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 6.752889e-04 3.171 0 0
L1CAM interactions R-HSA-373760 6.696402e-04 3.174 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 6.886949e-04 3.162 0 0
Recycling pathway of L1 R-HSA-437239 7.203851e-04 3.142 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 7.452624e-04 3.128 0 0
Gene expression (Transcription) R-HSA-74160 7.629244e-04 3.118 0 0
Polo-like kinase mediated events R-HSA-156711 7.683644e-04 3.114 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 7.683644e-04 3.114 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 8.200652e-04 3.086 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 8.897980e-04 3.051 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 9.434538e-04 3.025 0 0
Signaling by NOTCH1 R-HSA-1980143 9.837422e-04 3.007 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.171918e-03 2.931 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.084704e-03 2.965 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.130966e-03 2.947 0 0
Mitotic Prophase R-HSA-68875 1.112902e-03 2.954 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 1.104628e-03 2.957 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.087582e-03 2.964 0 0
Signaling by PTK6 R-HSA-8848021 1.167289e-03 2.933 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.167289e-03 2.933 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.138484e-03 2.944 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.225806e-03 2.912 0 0
Mitotic Anaphase R-HSA-68882 1.331655e-03 2.876 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.421537e-03 2.847 0 0
Nuclear import of Rev protein R-HSA-180746 1.443265e-03 2.841 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.455377e-03 2.837 0 0
Kinesins R-HSA-983189 1.548450e-03 2.810 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 1.695392e-03 2.771 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.823593e-03 2.739 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 2.147464e-03 2.668 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.147464e-03 2.668 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 2.426061e-03 2.615 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 2.293202e-03 2.640 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 2.381586e-03 2.623 0 0
tRNA processing in the nucleus R-HSA-6784531 2.171418e-03 2.663 0 0
G1/S-Specific Transcription R-HSA-69205 2.260013e-03 2.646 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.356846e-03 2.628 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.457663e-03 2.609 0 0
TGFBR3 expression R-HSA-9839394 2.636548e-03 2.579 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.718843e-03 2.566 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 2.949267e-03 2.530 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 2.949267e-03 2.530 0 0
snRNP Assembly R-HSA-191859 2.877668e-03 2.541 0 0
Metabolism of non-coding RNA R-HSA-194441 2.877668e-03 2.541 0 0
Post NMDA receptor activation events R-HSA-438064 2.818358e-03 2.550 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 3.325473e-03 2.478 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 3.386236e-03 2.470 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.427720e-03 2.465 0 0
Notch-HLH transcription pathway R-HSA-350054 3.486673e-03 2.458 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 3.562733e-03 2.448 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 3.609952e-03 2.442 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 4.039601e-03 2.394 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 4.039601e-03 2.394 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 4.174878e-03 2.379 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 4.192301e-03 2.378 0 0
Amplification of signal from the kinetochores R-HSA-141424 4.192301e-03 2.378 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 4.222186e-03 2.374 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.606997e-03 2.337 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 4.614708e-03 2.336 0 0
HATs acetylate histones R-HSA-3214847 4.592926e-03 2.338 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.592926e-03 2.338 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 5.049701e-03 2.297 0 0
RET signaling R-HSA-8853659 5.590365e-03 2.253 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 5.997433e-03 2.222 0 0
Separation of Sister Chromatids R-HSA-2467813 6.003012e-03 2.222 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 6.067387e-03 2.217 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 6.077469e-03 2.216 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 7.131799e-03 2.147 0 0
GLI proteins bind promoters of Hh responsive genes to promote transcription R-HSA-5635851 7.131799e-03 2.147 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 7.243823e-03 2.140 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 7.243823e-03 2.140 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 8.265150e-03 2.083 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 7.064494e-03 2.151 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 7.064494e-03 2.151 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 7.064494e-03 2.151 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 7.064494e-03 2.151 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 7.064494e-03 2.151 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 8.155868e-03 2.089 0 0
Cellular response to heat stress R-HSA-3371556 7.097609e-03 2.149 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.011989e-03 2.154 0 0
Epigenetic regulation of gene expression R-HSA-212165 6.930394e-03 2.159 0 0
Activation of RAC1 R-HSA-428540 7.531931e-03 2.123 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 7.040594e-03 2.152 0 0
Interleukin-17 signaling R-HSA-448424 7.164797e-03 2.145 0 0
Transport of connexons to the plasma membrane R-HSA-190872 7.985636e-03 2.098 0 0
Signaling by ALK in cancer R-HSA-9700206 7.040594e-03 2.152 0 0
MAP kinase activation R-HSA-450294 8.155868e-03 2.089 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 8.196724e-03 2.086 0 0
Apoptotic execution phase R-HSA-75153 7.609872e-03 2.119 0 0
Interleukin-37 signaling R-HSA-9008059 8.265150e-03 2.083 0 0
RNA Polymerase II Transcription R-HSA-73857 8.685286e-03 2.061 0 0
Mitotic Spindle Checkpoint R-HSA-69618 9.251512e-03 2.034 0 0
Signaling by ALK R-HSA-201556 9.689974e-03 2.014 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.024892e-02 1.989 0 0
Death Receptor Signaling R-HSA-73887 1.050954e-02 1.978 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.061239e-02 1.974 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.063035e-02 1.973 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.113406e-02 1.953 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 1.141780e-02 1.942 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.142271e-02 1.942 0 0
Aggrephagy R-HSA-9646399 1.148610e-02 1.940 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.258461e-02 1.900 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.359626e-02 1.867 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 1.359626e-02 1.867 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.353145e-02 1.869 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.386078e-02 1.858 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.350527e-02 1.869 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.388184e-02 1.858 0 0
Signaling by ERBB2 R-HSA-1227986 1.408455e-02 1.851 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.408455e-02 1.851 0 0
Signaling by NOTCH3 R-HSA-9012852 1.413074e-02 1.850 0 0
Circadian clock R-HSA-9909396 1.436264e-02 1.843 0 0
MHC class II antigen presentation R-HSA-2132295 1.436611e-02 1.843 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.464110e-02 1.834 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.504359e-02 1.823 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 1.504359e-02 1.823 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 1.644943e-02 1.784 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.618059e-02 1.791 0 0
ERK/MAPK targets R-HSA-198753 1.647256e-02 1.783 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.504359e-02 1.823 0 0
Neurodegenerative Diseases R-HSA-8863678 1.504359e-02 1.823 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.611420e-02 1.793 0 0
Cellular responses to stress R-HSA-2262752 1.743189e-02 1.759 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.768012e-02 1.753 0 0
Heme signaling R-HSA-9707616 1.820295e-02 1.740 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.845374e-02 1.734 0 0
mRNA 3'-end processing R-HSA-72187 1.860014e-02 1.730 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.864954e-02 1.729 0 0
G alpha (12/13) signalling events R-HSA-416482 1.905883e-02 1.720 0 0
Cell Cycle Checkpoints R-HSA-69620 1.925085e-02 1.716 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.948281e-02 1.710 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 1.972797e-02 1.705 0 0
NrCAM interactions R-HSA-447038 2.081447e-02 1.682 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.081447e-02 1.682 0 0
NGF-stimulated transcription R-HSA-9031628 2.139578e-02 1.670 0 0
Membrane Trafficking R-HSA-199991 2.143259e-02 1.669 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 2.195010e-02 1.659 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 2.512439e-02 1.600 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 2.409135e-02 1.618 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.409135e-02 1.618 0 0
G2/M Transition R-HSA-69275 2.289471e-02 1.640 0 0
ESR-mediated signaling R-HSA-8939211 2.233766e-02 1.651 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 2.224607e-02 1.653 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 2.461863e-02 1.609 0 0
MAPK family signaling cascades R-HSA-5683057 2.601244e-02 1.585 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.605160e-02 1.584 0 0
RUNX2 regulates bone development R-HSA-8941326 2.822355e-02 1.549 0 0
Viral Messenger RNA Synthesis R-HSA-168325 3.007009e-02 1.522 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.019674e-02 1.520 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 3.090389e-02 1.510 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 3.172234e-02 1.499 0 0
Signaling by TGFBR3 R-HSA-9839373 3.221988e-02 1.492 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.260393e-02 1.487 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 3.260393e-02 1.487 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.271238e-02 1.485 0 0
Interleukin-15 signaling R-HSA-8983432 3.283146e-02 1.484 0 0
Signaling by LTK R-HSA-9842663 3.283146e-02 1.484 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.344187e-02 1.476 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.371395e-02 1.472 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 3.378144e-02 1.471 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.384754e-02 1.470 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 3.403257e-02 1.468 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 3.562599e-02 1.448 0 0
Diseases of Telomere Maintenance R-HSA-9673013 3.562599e-02 1.448 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 3.562599e-02 1.448 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 3.562599e-02 1.448 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 3.562599e-02 1.448 0 0
The NLRP1 inflammasome R-HSA-844455 3.854672e-02 1.414 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 3.854672e-02 1.414 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 3.804389e-02 1.420 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 3.804389e-02 1.420 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 3.774705e-02 1.423 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.055856e-02 1.392 0 0
Resolution of D-Loop Structures R-HSA-5693537 3.774705e-02 1.423 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.804389e-02 1.420 0 0
Signaling by TGFB family members R-HSA-9006936 3.844900e-02 1.415 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 3.537515e-02 1.451 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 4.117394e-02 1.385 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 4.192664e-02 1.378 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 4.192664e-02 1.378 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 4.192664e-02 1.378 0 0
Regulation of beta-cell development R-HSA-186712 4.346377e-02 1.362 0 0
Activation of BH3-only proteins R-HSA-114452 4.359359e-02 1.361 0 0
RAF activation R-HSA-5673000 4.362521e-02 1.360 0 0
Signal attenuation R-HSA-74749 4.496787e-02 1.347 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 4.496787e-02 1.347 0 0
CREB phosphorylation R-HSA-199920 4.542633e-02 1.343 0 0
HIV Life Cycle R-HSA-162587 4.625001e-02 1.335 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 4.667184e-02 1.331 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 4.832843e-02 1.316 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 4.901623e-02 1.310 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 5.994379e-02 1.222 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 5.994379e-02 1.222 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 5.994379e-02 1.222 0 0
Signaling by APC mutants R-HSA-4839744 5.802836e-02 1.236 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 5.802836e-02 1.236 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 5.802836e-02 1.236 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 5.802836e-02 1.236 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 5.246459e-02 1.280 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 5.645711e-02 1.248 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 5.827672e-02 1.235 0 0
Diseases of mitotic cell cycle R-HSA-9675126 5.825079e-02 1.235 0 0
Signaling by EGFR R-HSA-177929 5.599388e-02 1.252 0 0
AURKA Activation by TPX2 R-HSA-8854518 5.130078e-02 1.290 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 5.827672e-02 1.235 0 0
Oncogene Induced Senescence R-HSA-2559585 5.010300e-02 1.300 0 0
Signaling by NOTCH R-HSA-157118 5.127021e-02 1.290 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 5.825079e-02 1.235 0 0
TCF dependent signaling in response to WNT R-HSA-201681 5.682363e-02 1.245 0 0
Generic Transcription Pathway R-HSA-212436 5.580484e-02 1.253 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.451289e-02 1.264 0 0
Myogenesis R-HSA-525793 5.038644e-02 1.298 0 0
Signaling downstream of RAS mutants R-HSA-9649948 6.067565e-02 1.217 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 6.067565e-02 1.217 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 6.067565e-02 1.217 0 0
Signaling by RAS mutants R-HSA-6802949 6.067565e-02 1.217 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 6.194088e-02 1.208 0 0
PTK6 Expression R-HSA-8849473 6.194088e-02 1.208 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 6.194088e-02 1.208 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 6.194088e-02 1.208 0 0
Signaling by FGFR1 in disease R-HSA-5655302 6.289705e-02 1.201 0 0
Apoptosis R-HSA-109581 6.298164e-02 1.201 0 0
Telomere C-strand synthesis initiation R-HSA-174430 6.447640e-02 1.191 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 6.493307e-02 1.188 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 6.665632e-02 1.176 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 6.665632e-02 1.176 0 0
PKR-mediated signaling R-HSA-9833482 6.696805e-02 1.174 0 0
Cellular responses to stimuli R-HSA-8953897 6.734241e-02 1.172 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 6.742414e-02 1.171 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 7.062946e-02 1.151 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.281751e-02 1.138 0 0
Loss of Function of SMAD4 in Cancer R-HSA-3304347 7.290174e-02 1.137 0 0
SMAD4 MH2 Domain Mutants in Cancer R-HSA-3311021 7.290174e-02 1.137 0 0
SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-3315487 7.290174e-02 1.137 0 0
Breakdown of the nuclear lamina R-HSA-352238 7.290174e-02 1.137 0 0
Signaling by GSK3beta mutants R-HSA-5339716 7.303423e-02 1.136 0 0
Signaling by AMER1 mutants R-HSA-4839748 7.303423e-02 1.136 0 0
Signaling by AXIN mutants R-HSA-4839735 7.303423e-02 1.136 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 8.574296e-02 1.067 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 8.574296e-02 1.067 0 0
IRS activation R-HSA-74713 8.574296e-02 1.067 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 8.574296e-02 1.067 0 0
Type I hemidesmosome assembly R-HSA-446107 8.118993e-02 1.090 0 0
RSK activation R-HSA-444257 8.118993e-02 1.090 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 8.118993e-02 1.090 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 8.118993e-02 1.090 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 8.995003e-02 1.046 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 8.995003e-02 1.046 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 8.995003e-02 1.046 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 8.995003e-02 1.046 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 8.995003e-02 1.046 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 7.958277e-02 1.099 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 7.958277e-02 1.099 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 7.958277e-02 1.099 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 7.958277e-02 1.099 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 7.929570e-02 1.101 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 9.129590e-02 1.040 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 7.788379e-02 1.109 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.788379e-02 1.109 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 7.907739e-02 1.102 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 8.490539e-02 1.071 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 8.846714e-02 1.053 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.568338e-02 1.067 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 8.995003e-02 1.046 0 0
COPI-mediated anterograde transport R-HSA-6807878 7.770417e-02 1.110 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 7.450092e-02 1.128 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 8.874559e-02 1.052 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 7.796954e-02 1.108 0 0
Differentiation of T cells R-HSA-9945266 7.796954e-02 1.108 0 0
Organelle biogenesis and maintenance R-HSA-1852241 8.990959e-02 1.046 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 7.456260e-02 1.127 0 0
HDMs demethylate histones R-HSA-3214842 9.129590e-02 1.040 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.568338e-02 1.067 0 0
Long-term potentiation R-HSA-9620244 9.129590e-02 1.040 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 8.778620e-02 1.057 0 0
Inositol phosphate metabolism R-HSA-1483249 7.548204e-02 1.122 0 0
XBP1(S) activates chaperone genes R-HSA-381038 7.468770e-02 1.127 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 9.205029e-02 1.036 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.292857e-02 1.032 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 9.292857e-02 1.032 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 9.600434e-02 1.018 0 0
Signalling to ERKs R-HSA-187687 9.631403e-02 1.016 1 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 9.915808e-02 1.004 1 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 9.918703e-02 1.004 0 0
Nervous system development R-HSA-9675108 1.019433e-01 0.992 0 0
FLT3 Signaling R-HSA-9607240 1.024102e-01 0.990 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 1.030224e-01 0.987 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.030224e-01 0.987 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.036177e-01 0.985 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.074420e-01 0.969 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.079635e-01 0.967 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.079635e-01 0.967 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 1.087037e-01 0.964 0 0
Formation of axial mesoderm R-HSA-9796292 1.087037e-01 0.964 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.093164e-01 0.961 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.093164e-01 0.961 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 1.093164e-01 0.961 0 0
Signaling by Hippo R-HSA-2028269 1.093164e-01 0.961 0 0
Signaling by WNT in cancer R-HSA-4791275 1.130117e-01 0.947 0 0
MAP2K and MAPK activation R-HSA-5674135 1.134275e-01 0.945 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.134275e-01 0.945 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 1.150492e-01 0.939 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 1.153977e-01 0.938 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 1.153977e-01 0.938 0 0
Signaling by RNF43 mutants R-HSA-5340588 1.153977e-01 0.938 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.153977e-01 0.938 0 0
IRE1alpha activates chaperones R-HSA-381070 1.160158e-01 0.935 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 1.167491e-01 0.933 0 0
Regulation of TP53 Expression R-HSA-6804754 1.180189e-01 0.928 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.180189e-01 0.928 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.192974e-01 0.923 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.232937e-01 0.909 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.367560e-01 0.864 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 1.367560e-01 0.864 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.367560e-01 0.864 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 1.367560e-01 0.864 0 0
MET interacts with TNS proteins R-HSA-8875513 1.681375e-01 0.774 0 0
Activation of BMF and translocation to mitochondria R-HSA-139910 1.681375e-01 0.774 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 1.681375e-01 0.774 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 1.291912e-01 0.889 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.291912e-01 0.889 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.512822e-01 0.820 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 1.512822e-01 0.820 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.270763e-01 0.896 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.270763e-01 0.896 0 0
Ephrin signaling R-HSA-3928664 1.270763e-01 0.896 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.405728e-01 0.852 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.405728e-01 0.852 0 0
DAP12 signaling R-HSA-2424491 1.655949e-01 0.781 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.655949e-01 0.781 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.585597e-01 0.800 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.592889e-01 0.798 0 0
Signaling by NOTCH2 R-HSA-1980145 1.555289e-01 0.808 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 1.326171e-01 0.877 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.421975e-01 0.847 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 1.263908e-01 0.898 0 0
Adipogenesis R-HSA-9843745 1.460972e-01 0.835 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.638478e-01 0.786 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.592889e-01 0.798 0 0
HDACs deacetylate histones R-HSA-3214815 1.438767e-01 0.842 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.403243e-01 0.853 0 0
Neurofascin interactions R-HSA-447043 1.482844e-01 0.829 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.438767e-01 0.842 0 0
Interleukin-2 family signaling R-HSA-451927 1.603433e-01 0.795 0 0
ER to Golgi Anterograde Transport R-HSA-199977 1.432457e-01 0.844 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.438863e-01 0.842 0 0
Cardiogenesis R-HSA-9733709 1.263908e-01 0.898 0 0
Regulation of KIT signaling R-HSA-1433559 1.291912e-01 0.889 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.455245e-01 0.837 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.398326e-01 0.854 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.567837e-01 0.805 0 0
Gap junction assembly R-HSA-190861 1.555289e-01 0.808 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 1.461337e-01 0.835 0 0
Mitochondrial biogenesis R-HSA-1592230 1.652398e-01 0.782 0 0
HIV Infection R-HSA-162906 1.509395e-01 0.821 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.326891e-01 0.877 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.326891e-01 0.877 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.326891e-01 0.877 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.272282e-01 0.895 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.270763e-01 0.896 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.398326e-01 0.854 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 1.489321e-01 0.827 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 1.263908e-01 0.898 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.407494e-01 0.852 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.407494e-01 0.852 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 1.263908e-01 0.898 0 0
Signaling by Leptin R-HSA-2586552 1.272282e-01 0.895 0 0
DCC mediated attractive signaling R-HSA-418885 1.512822e-01 0.820 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 1.326171e-01 0.877 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.596642e-01 0.797 0 0
Selective autophagy R-HSA-9663891 1.318811e-01 0.880 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.535538e-01 0.814 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 1.555289e-01 0.808 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 1.712242e-01 0.766 0 0
Host Interactions of HIV factors R-HSA-162909 1.726560e-01 0.763 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 1.751928e-01 0.756 0 0
Diseases of DNA repair R-HSA-9675135 1.779512e-01 0.750 0 0
Protein folding R-HSA-391251 1.798149e-01 0.745 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 1.817164e-01 0.741 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 1.817164e-01 0.741 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 1.817164e-01 0.741 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.817164e-01 0.741 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 1.817164e-01 0.741 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.830694e-01 0.737 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 1.837527e-01 0.736 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.837527e-01 0.736 0 0
SOS-mediated signalling R-HSA-112412 1.837527e-01 0.736 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 1.837527e-01 0.736 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 1.837527e-01 0.736 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 1.837527e-01 0.736 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.843675e-01 0.734 0 0
FLT3 signaling in disease R-HSA-9682385 1.876191e-01 0.727 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.877694e-01 0.726 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.877694e-01 0.726 0 0
Signalling to RAS R-HSA-167044 1.877694e-01 0.726 1 0
DNA Double-Strand Break Repair R-HSA-5693532 1.890103e-01 0.724 0 0
Cilium Assembly R-HSA-5617833 1.912265e-01 0.718 0 0
Meiotic synapsis R-HSA-1221632 1.937437e-01 0.713 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.940045e-01 0.712 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 2.548166e-01 0.594 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 2.548166e-01 0.594 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 2.548166e-01 0.594 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 2.548166e-01 0.594 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 2.548166e-01 0.594 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 2.548166e-01 0.594 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 2.210471e-01 0.656 0 0
Regulation of gap junction activity R-HSA-191650 2.210471e-01 0.656 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 2.210471e-01 0.656 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 2.210471e-01 0.656 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 2.210471e-01 0.656 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 2.210471e-01 0.656 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 3.567367e-01 0.448 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 3.567367e-01 0.448 0 0
Defective SLC9A9 causes autism 16 (AUTS16) R-HSA-5619052 3.567367e-01 0.448 0 0
Defective VWF binding to collagen type I R-HSA-9845622 3.567367e-01 0.448 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 3.567367e-01 0.448 0 0
Intestinal infectious diseases R-HSA-8942233 3.567367e-01 0.448 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5660686 3.567367e-01 0.448 0 0
Defective MMADHC causes MMAHCD R-HSA-3359473 3.567367e-01 0.448 0 0
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) R-HSA-5619101 3.567367e-01 0.448 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 3.567367e-01 0.448 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 3.567367e-01 0.448 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.750478e-01 0.561 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.750478e-01 0.561 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.750478e-01 0.561 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 2.750478e-01 0.561 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 2.211623e-01 0.655 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 2.211623e-01 0.655 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 2.211623e-01 0.655 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 2.114161e-01 0.675 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 2.114161e-01 0.675 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 2.114161e-01 0.675 0 0
GP1b-IX-V activation signalling R-HSA-430116 2.599065e-01 0.585 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 2.599065e-01 0.585 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 3.288523e-01 0.483 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 3.288523e-01 0.483 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 3.288523e-01 0.483 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 3.288523e-01 0.483 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 3.288523e-01 0.483 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 3.288523e-01 0.483 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 3.288523e-01 0.483 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 3.288523e-01 0.483 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 3.288523e-01 0.483 0 0
Signaling by MAPK mutants R-HSA-9652817 3.288523e-01 0.483 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.447220e-01 0.352 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.447220e-01 0.352 0 0
Signalling to ERK5 R-HSA-198765 4.447220e-01 0.352 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.447220e-01 0.352 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.447220e-01 0.352 0 0
Defective VWF cleavage by ADAMTS13 variant R-HSA-9845621 4.447220e-01 0.352 0 0
Defective F8 sulfation at Y1699 R-HSA-9674519 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.447220e-01 0.352 0 0
Enhanced cleavage of VWF variant by ADAMTS13 R-HSA-9845619 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.447220e-01 0.352 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.447220e-01 0.352 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.447220e-01 0.352 0 0
Glycogen storage disease type IV (GBE1) R-HSA-3878781 4.447220e-01 0.352 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 1.996519e-01 0.700 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 2.423475e-01 0.616 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 2.994278e-01 0.524 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 2.994278e-01 0.524 0 0
DNA replication initiation R-HSA-68952 2.994278e-01 0.524 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 2.742076e-01 0.562 0 0
Retrograde neurotrophin signalling R-HSA-177504 2.742076e-01 0.562 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 3.815046e-01 0.419 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.815046e-01 0.419 0 0
Autointegration results in viral DNA circles R-HSA-177539 3.815046e-01 0.419 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.524391e-01 0.598 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 3.392270e-01 0.470 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 3.392270e-01 0.470 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 2.164524e-01 0.665 0 0
Spry regulation of FGF signaling R-HSA-1295596 3.067039e-01 0.513 0 0
Processive synthesis on the lagging strand R-HSA-69183 3.067039e-01 0.513 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 3.067039e-01 0.513 0 0
E2F mediated regulation of DNA replication R-HSA-113510 2.800282e-01 0.553 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.573520e-01 0.589 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 2.202215e-01 0.657 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 3.788668e-01 0.422 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 3.788668e-01 0.422 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 3.788668e-01 0.422 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 3.788668e-01 0.422 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 4.323137e-01 0.364 0 0
IFNG signaling activates MAPKs R-HSA-9732724 4.323137e-01 0.364 0 0
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974 4.323137e-01 0.364 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 4.323137e-01 0.364 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 4.323137e-01 0.364 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 4.323137e-01 0.364 0 0
Recycling of eIF2:GDP R-HSA-72731 4.323137e-01 0.364 0 0
MET activates STAT3 R-HSA-8875791 5.206771e-01 0.283 0 0
PLC-gamma1 signalling R-HSA-167021 5.206771e-01 0.283 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 5.206771e-01 0.283 0 0
Axonal growth stimulation R-HSA-209563 5.206771e-01 0.283 0 0
Defective MMACHC causes MAHCC R-HSA-3359474 5.206771e-01 0.283 0 0
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336 5.206771e-01 0.283 0 0
MET activates PTPN11 R-HSA-8865999 5.206771e-01 0.283 0 0
Classical Kir channels R-HSA-1296053 5.206771e-01 0.283 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 5.206771e-01 0.283 0 0
Signalling to STAT3 R-HSA-198745 5.206771e-01 0.283 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 5.206771e-01 0.283 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 3.366767e-01 0.473 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 2.592414e-01 0.586 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 3.725152e-01 0.429 0 0
Trafficking of AMPA receptors R-HSA-399719 3.046153e-01 0.516 0 0
Polymerase switching R-HSA-69091 4.179726e-01 0.379 0 0
Leading Strand Synthesis R-HSA-69109 4.179726e-01 0.379 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.195410e-01 0.658 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 2.758487e-01 0.559 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.653834e-01 0.437 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 2.979205e-01 0.526 0 0
HIV Transcription Initiation R-HSA-167161 2.979205e-01 0.526 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 2.979205e-01 0.526 0 0
Signaling by ERBB4 R-HSA-1236394 2.328297e-01 0.633 0 0
Interaction between L1 and Ankyrins R-HSA-445095 3.581960e-01 0.446 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 4.053371e-01 0.392 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 4.807991e-01 0.318 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 4.807991e-01 0.318 0 0
Formation of annular gap junctions R-HSA-196025 4.807991e-01 0.318 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 4.807991e-01 0.318 0 0
MET receptor recycling R-HSA-8875656 4.807991e-01 0.318 0 0
Centrosome maturation R-HSA-380287 2.464393e-01 0.608 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.863176e-01 0.543 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.029403e-01 0.519 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 3.378853e-01 0.471 0 0
CD28 dependent Vav1 pathway R-HSA-389359 4.562307e-01 0.341 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 4.562307e-01 0.341 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 4.227474e-01 0.374 0 0
Signaling by Erythropoietin R-HSA-9006335 4.098194e-01 0.387 0 0
Late endosomal microautophagy R-HSA-9615710 4.098194e-01 0.387 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 3.786520e-01 0.422 0 0
Processing of DNA double-strand break ends R-HSA-5693607 3.335953e-01 0.477 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 3.991870e-01 0.399 0 0
Activation of the pre-replicative complex R-HSA-68962 4.355260e-01 0.361 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 4.697570e-01 0.328 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 4.697570e-01 0.328 0 0
Removal of the Flap Intermediate R-HSA-69166 4.933844e-01 0.307 0 0
ARMS-mediated activation R-HSA-170984 5.266459e-01 0.278 0 0
Gap junction degradation R-HSA-190873 5.266459e-01 0.278 0 0
HCN channels R-HSA-1296061 5.862463e-01 0.232 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 5.862463e-01 0.232 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 5.862463e-01 0.232 0 0
Signaling by MAP2K mutants R-HSA-9652169 5.862463e-01 0.232 0 0
Signaling by LRP5 mutants R-HSA-5339717 5.862463e-01 0.232 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.086650e-01 0.389 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 4.197460e-01 0.377 0 0
EGFR downregulation R-HSA-182971 4.610253e-01 0.336 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 4.537641e-01 0.343 0 0
Erythropoietin activates RAS R-HSA-9027284 5.292300e-01 0.276 0 0
SHC1 events in EGFR signaling R-HSA-180336 5.292300e-01 0.276 0 0
mRNA Splicing R-HSA-72172 3.821116e-01 0.418 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 5.065758e-01 0.295 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 5.065758e-01 0.295 0 0
mRNA Splicing - Major Pathway R-HSA-72163 4.053040e-01 0.392 0 0
Lagging Strand Synthesis R-HSA-69186 5.314234e-01 0.275 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 5.696689e-01 0.244 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 5.696689e-01 0.244 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 4.811216e-01 0.318 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 5.049158e-01 0.297 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 5.334601e-01 0.273 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 5.210412e-01 0.283 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 5.636112e-01 0.249 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.636112e-01 0.249 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 5.608939e-01 0.251 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 5.608939e-01 0.251 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 5.406652e-01 0.267 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 5.596595e-01 0.252 0 0
Telomere Extension By Telomerase R-HSA-171319 5.596595e-01 0.252 0 0
HIV elongation arrest and recovery R-HSA-167287 5.596595e-01 0.252 0 0
Pausing and recovery of HIV elongation R-HSA-167290 5.596595e-01 0.252 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 5.595016e-01 0.252 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 5.628341e-01 0.250 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 5.851003e-01 0.233 0 0
Transcription of the HIV genome R-HSA-167172 4.417899e-01 0.355 0 0
Signaling by EGFR in Cancer R-HSA-1643713 3.325028e-01 0.478 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 5.816282e-01 0.235 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 5.816282e-01 0.235 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 5.816282e-01 0.235 0 0
MITF-M-dependent gene expression R-HSA-9856651 2.172322e-01 0.663 0 0
DNA Double Strand Break Response R-HSA-5693606 4.242031e-01 0.372 0 0
FOXO-mediated transcription R-HSA-9614085 1.995452e-01 0.700 0 0
Cyclin D associated events in G1 R-HSA-69231 2.403707e-01 0.619 0 0
G1 Phase R-HSA-69236 2.403707e-01 0.619 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 4.319393e-01 0.365 0 0
Hedgehog 'off' state R-HSA-5610787 2.103047e-01 0.677 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 5.353869e-01 0.271 0 0
Formation of definitive endoderm R-HSA-9823730 3.081675e-01 0.511 0 0
Integrin signaling R-HSA-354192 3.511783e-01 0.454 0 0
HCMV Early Events R-HSA-9609690 3.583510e-01 0.446 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 4.098194e-01 0.387 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 4.355260e-01 0.361 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 5.824364e-01 0.235 0 0
MET activates RAS signaling R-HSA-8851805 2.114161e-01 0.675 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 2.573520e-01 0.589 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 3.081675e-01 0.511 0 0
Prolonged ERK activation events R-HSA-169893 3.395590e-01 0.469 0 0
Extension of Telomeres R-HSA-180786 5.237208e-01 0.281 0 0
Hedgehog 'on' state R-HSA-5632684 4.941816e-01 0.306 0 0
Activation of SMO R-HSA-5635838 5.636112e-01 0.249 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 2.179215e-01 0.662 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 2.423475e-01 0.616 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 3.395590e-01 0.469 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 3.970282e-01 0.401 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 5.824364e-01 0.235 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 2.742076e-01 0.562 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 3.802394e-01 0.420 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 4.941816e-01 0.306 0 0
Signaling by FGFR4 R-HSA-5654743 2.232878e-01 0.651 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 5.180962e-01 0.286 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 4.197460e-01 0.377 0 0
Signaling by FGFR2 R-HSA-5654738 5.306453e-01 0.275 0 0
Frs2-mediated activation R-HSA-170968 4.562307e-01 0.341 0 0
Neurexins and neuroligins R-HSA-6794361 2.730095e-01 0.564 0 0
Homology Directed Repair R-HSA-5693538 2.347706e-01 0.629 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 2.599065e-01 0.585 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.524391e-01 0.598 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 4.319393e-01 0.365 0 0
Regulation of the apoptosome activity R-HSA-9627069 5.696689e-01 0.244 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.306453e-01 0.275 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 2.986260e-01 0.525 0 0
Nephron development R-HSA-9831926 2.524391e-01 0.598 0 0
Regulation of endogenous retroelements R-HSA-9842860 4.952332e-01 0.305 0 0
PERK regulates gene expression R-HSA-381042 5.824364e-01 0.235 0 0
Signaling by FGFR3 R-HSA-5654741 2.579066e-01 0.589 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 3.121270e-01 0.506 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 2.164524e-01 0.665 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 3.277694e-01 0.484 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 3.635331e-01 0.439 0 0
Signaling by Activin R-HSA-1502540 5.292300e-01 0.276 0 0
Formation of apoptosome R-HSA-111458 5.696689e-01 0.244 0 0
PI3K/AKT activation R-HSA-198203 5.696689e-01 0.244 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 5.608939e-01 0.251 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 2.232878e-01 0.651 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 2.270478e-01 0.644 0 0
Activation of ATR in response to replication stress R-HSA-176187 5.110366e-01 0.292 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.195586e-01 0.377 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.978202e-01 0.704 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.978202e-01 0.704 0 0
Signaling by Hedgehog R-HSA-5358351 4.276369e-01 0.369 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 2.211623e-01 0.655 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.179726e-01 0.379 0 0
mTORC1-mediated signalling R-HSA-166208 3.941243e-01 0.404 0 0
Meiosis R-HSA-1500620 2.986260e-01 0.525 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 5.862463e-01 0.232 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 4.045738e-01 0.393 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 2.333687e-01 0.632 0 0
Signaling by FGFR1 R-HSA-5654736 4.667391e-01 0.331 0 0
Germ layer formation at gastrulation R-HSA-9754189 4.697570e-01 0.328 0 0
Signaling by MET R-HSA-6806834 4.204175e-01 0.376 0 0
Signaling by Nuclear Receptors R-HSA-9006931 2.390221e-01 0.622 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.101328e-01 0.678 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.598769e-01 0.585 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 2.592414e-01 0.586 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 2.592414e-01 0.586 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 4.053371e-01 0.392 0 0
Rap1 signalling R-HSA-392517 4.697570e-01 0.328 0 0
PTEN Regulation R-HSA-6807070 4.398790e-01 0.357 0 0
S Phase R-HSA-69242 1.996464e-01 0.700 0 0
Gap junction trafficking and regulation R-HSA-157858 2.234452e-01 0.651 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 3.498612e-01 0.456 1 1
MTOR signalling R-HSA-165159 4.537641e-01 0.343 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.191589e-01 0.496 0 0
G1/S Transition R-HSA-69206 2.526809e-01 0.597 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 2.750478e-01 0.561 0 0
Calcineurin activates NFAT R-HSA-2025928 2.599065e-01 0.585 0 0
Diseases of cellular response to stress R-HSA-9675132 4.447220e-01 0.352 0 0
Diseases of Cellular Senescence R-HSA-9630747 4.447220e-01 0.352 0 0
Signaling by FGFR4 in disease R-HSA-5655291 2.742076e-01 0.562 0 0
Nuclear RNA decay R-HSA-9930044 2.202215e-01 0.657 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 3.395590e-01 0.469 0 0
Killing mechanisms R-HSA-9664420 3.395590e-01 0.469 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 3.070473e-01 0.513 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 3.725152e-01 0.429 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 2.209724e-01 0.656 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 4.537641e-01 0.343 0 0
Signaling by NODAL R-HSA-1181150 5.010063e-01 0.300 0 0
MET promotes cell motility R-HSA-8875878 4.920105e-01 0.308 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 5.314234e-01 0.275 0 0
Developmental Biology R-HSA-1266738 5.193986e-01 0.284 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.077811e-01 0.682 0 0
Gap junction trafficking R-HSA-190828 2.403707e-01 0.619 0 0
Signaling by SCF-KIT R-HSA-1433557 2.232878e-01 0.651 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.202215e-01 0.657 0 0
Signaling by VEGF R-HSA-194138 4.931737e-01 0.307 1 0
Signaling by WNT R-HSA-195721 2.848921e-01 0.545 0 0
UCH proteinases R-HSA-5689603 3.559743e-01 0.449 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 4.720536e-01 0.326 0 0
Interleukin-2 signaling R-HSA-9020558 3.392270e-01 0.470 0 0
DNA Repair R-HSA-73894 3.063167e-01 0.514 0 0
p75NTR regulates axonogenesis R-HSA-193697 5.266459e-01 0.278 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 4.565585e-01 0.341 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 3.070473e-01 0.513 0 0
Gastrulation R-HSA-9758941 5.724530e-01 0.242 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 3.325028e-01 0.478 0 0
Vesicle-mediated transport R-HSA-5653656 4.724994e-01 0.326 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 2.210471e-01 0.656 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 2.210471e-01 0.656 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 2.333687e-01 0.632 0 0
Formation of the anterior neural plate R-HSA-9823739 5.292300e-01 0.276 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.636112e-01 0.249 0 0
Diseases of programmed cell death R-HSA-9645723 3.567737e-01 0.448 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 3.188947e-01 0.496 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 2.348526e-01 0.629 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 3.188947e-01 0.496 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 3.558790e-01 0.449 0 0
Signaling by FGFR in disease R-HSA-1226099 3.243861e-01 0.489 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 3.815046e-01 0.419 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.511783e-01 0.454 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 5.592111e-01 0.252 0 0
Downstream signal transduction R-HSA-186763 4.610253e-01 0.336 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 3.558790e-01 0.449 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.783901e-01 0.555 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 5.266459e-01 0.278 0 0
Metabolism of RNA R-HSA-8953854 5.448756e-01 0.264 0 0
TNF signaling R-HSA-75893 3.436137e-01 0.464 0 0
Signaling by NOTCH4 R-HSA-9013694 5.453699e-01 0.263 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.080066e-01 0.682 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 4.053371e-01 0.392 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 4.511127e-01 0.346 0 0
Protein-protein interactions at synapses R-HSA-6794362 5.010599e-01 0.300 0 0
Axon guidance R-HSA-422475 2.393767e-01 0.621 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 5.796222e-01 0.237 0 0
Regulation of TNFR1 signaling R-HSA-5357905 3.991870e-01 0.399 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 3.970282e-01 0.401 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 2.523420e-01 0.598 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 2.409699e-01 0.618 0 0
DAP12 interactions R-HSA-2172127 4.968987e-01 0.304 0 0
Semaphorin interactions R-HSA-373755 3.541530e-01 0.451 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 2.548166e-01 0.594 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.210471e-01 0.656 0 0
ARL13B-mediated ciliary trafficking of INPP5E R-HSA-5624958 3.567367e-01 0.448 0 0
Transport of connexins along the secretory pathway R-HSA-190827 3.567367e-01 0.448 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 3.567367e-01 0.448 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.750478e-01 0.561 0 0
Sodium/Proton exchangers R-HSA-425986 2.211623e-01 0.655 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 2.599065e-01 0.585 0 0
mRNA Editing: A to I Conversion R-HSA-75064 4.447220e-01 0.352 0 0
C6 deamination of adenosine R-HSA-75102 4.447220e-01 0.352 0 0
TGFBR3 regulates activin signaling R-HSA-9839406 4.447220e-01 0.352 0 0
Intracellular metabolism of fatty acids regulates insulin secretion R-HSA-434313 3.815046e-01 0.419 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 2.524391e-01 0.598 0 0
Negative regulation of FLT3 R-HSA-9706369 3.395590e-01 0.469 0 0
Regulation of PTEN localization R-HSA-8948747 4.323137e-01 0.364 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 5.206771e-01 0.283 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 5.206771e-01 0.283 0 0
Interleukin-23 signaling R-HSA-9020933 4.807991e-01 0.318 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 4.807991e-01 0.318 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 4.807991e-01 0.318 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 4.562307e-01 0.341 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 5.266459e-01 0.278 0 0
WNT mediated activation of DVL R-HSA-201688 5.266459e-01 0.278 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 5.862463e-01 0.232 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 5.862463e-01 0.232 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 5.696689e-01 0.244 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 5.696689e-01 0.244 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 5.148041e-01 0.288 0 0
Programmed Cell Death R-HSA-5357801 2.690153e-01 0.570 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.582699e-01 0.588 0 0
Ca2+ pathway R-HSA-4086398 5.284888e-01 0.277 0 0
Cell junction organization R-HSA-446728 3.340862e-01 0.476 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.653834e-01 0.437 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 3.320873e-01 0.479 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 2.600906e-01 0.585 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.790934e-01 0.320 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 2.998229e-01 0.523 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.432163e-01 0.265 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.432163e-01 0.265 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 4.260319e-01 0.371 0 0
Signal transduction by L1 R-HSA-445144 3.081675e-01 0.511 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 3.368947e-01 0.473 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.255848e-01 0.647 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 2.114161e-01 0.675 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.511783e-01 0.454 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 5.266459e-01 0.278 0 0
Effects of PIP2 hydrolysis R-HSA-114508 5.353869e-01 0.271 0 0
Deubiquitination R-HSA-5688426 4.859728e-01 0.313 0 0
Adherens junctions interactions R-HSA-418990 5.228943e-01 0.282 0 0
PI Metabolism R-HSA-1483255 3.990264e-01 0.399 0 0
Cell-Cell communication R-HSA-1500931 3.739900e-01 0.427 0 0
PECAM1 interactions R-HSA-210990 3.392270e-01 0.470 0 0
MDK and PTN in ALK signaling R-HSA-9851151 5.862463e-01 0.232 0 0
Receptor Mediated Mitophagy R-HSA-8934903 5.696689e-01 0.244 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 2.164524e-01 0.665 0 0
Regulation of gene expression in beta cells R-HSA-210745 4.098194e-01 0.387 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.903205e-01 0.310 0 0
Autophagy R-HSA-9612973 4.157686e-01 0.381 0 0
Nef and signal transduction R-HSA-164944 3.815046e-01 0.419 0 0
p38MAPK events R-HSA-171007 3.067039e-01 0.513 1 1
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 4.933844e-01 0.307 0 0
Interleukin-21 signaling R-HSA-9020958 5.266459e-01 0.278 0 0
Regulated proteolysis of p75NTR R-HSA-193692 5.266459e-01 0.278 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 5.862463e-01 0.232 0 0
Formation of intermediate mesoderm R-HSA-9761174 5.696689e-01 0.244 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 3.177725e-01 0.498 0 0
Inflammasomes R-HSA-622312 5.596595e-01 0.252 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 2.347706e-01 0.629 0 0
Macroautophagy R-HSA-1632852 4.643681e-01 0.333 0 0
RMTs methylate histone arginines R-HSA-3214858 3.581985e-01 0.446 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 4.610253e-01 0.336 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 5.148041e-01 0.288 0 0
Tie2 Signaling R-HSA-210993 4.378133e-01 0.359 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 5.314234e-01 0.275 0 0
Oligomerization of connexins into connexons R-HSA-190704 3.567367e-01 0.448 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 3.815046e-01 0.419 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 5.206771e-01 0.283 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.653834e-01 0.437 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 4.933844e-01 0.307 0 0
Cellular response to mitochondrial stress R-HSA-9840373 5.266459e-01 0.278 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 5.862463e-01 0.232 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.292300e-01 0.276 0 0
2-LTR circle formation R-HSA-164843 5.696689e-01 0.244 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 3.312203e-01 0.480 0 0
Nephrin family interactions R-HSA-373753 3.081675e-01 0.511 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 5.065758e-01 0.295 0 0
Pexophagy R-HSA-9664873 5.696689e-01 0.244 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 3.815046e-01 0.419 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.417899e-01 0.355 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 5.292300e-01 0.276 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.872623e-01 0.542 0 0
Netrin-1 signaling R-HSA-373752 4.968987e-01 0.304 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 2.202215e-01 0.657 0 0
MECP2 regulates transcription factors R-HSA-9022707 4.323137e-01 0.364 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.179726e-01 0.379 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 5.266459e-01 0.278 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 5.862463e-01 0.232 0 0
Dopamine receptors R-HSA-390651 5.862463e-01 0.232 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 5.862463e-01 0.232 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 5.608939e-01 0.251 0 0
Sensory processing of sound R-HSA-9659379 5.142786e-01 0.289 0 0
Gene Silencing by RNA R-HSA-211000 3.908321e-01 0.408 0 0
Interleukin-38 signaling R-HSA-9007892 5.862463e-01 0.232 0 0
Growth hormone receptor signaling R-HSA-982772 4.227474e-01 0.374 0 0
tRNA processing R-HSA-72306 5.098825e-01 0.293 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 4.667391e-01 0.331 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 5.893251e-01 0.230 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 5.893251e-01 0.230 0 0
LDL clearance R-HSA-8964038 5.893251e-01 0.230 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.952988e-01 0.225 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 5.962457e-01 0.225 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 5.964143e-01 0.224 0 0
Disorders of Developmental Biology R-HSA-9675151 5.964143e-01 0.224 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.964143e-01 0.224 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 5.964143e-01 0.224 0 0
GPVI-mediated activation cascade R-HSA-114604 6.050248e-01 0.218 0 0
G2/M Checkpoints R-HSA-69481 6.065995e-01 0.217 0 0
Formation of the posterior neural plate R-HSA-9832991 6.097827e-01 0.215 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 6.097827e-01 0.215 0 0
Ionotropic activity of kainate receptors R-HSA-451306 6.097827e-01 0.215 0 0
Synthesis of PI R-HSA-1483226 6.097827e-01 0.215 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 6.097827e-01 0.215 0 0
Suppression of apoptosis R-HSA-9635465 6.097827e-01 0.215 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 6.244450e-01 0.205 0 0
Ovarian tumor domain proteases R-HSA-5689896 6.269285e-01 0.203 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 6.275625e-01 0.202 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 6.275625e-01 0.202 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 6.275625e-01 0.202 0 0
HCMV Infection R-HSA-9609646 6.292929e-01 0.201 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 6.315966e-01 0.200 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 6.334733e-01 0.198 0 0
Cargo concentration in the ER R-HSA-5694530 6.334733e-01 0.198 0 0
Budding and maturation of HIV virion R-HSA-162588 6.334733e-01 0.198 0 0
EPHB-mediated forward signaling R-HSA-3928662 6.419661e-01 0.192 0 0
Interferon Signaling R-HSA-913531 6.422149e-01 0.192 0 0
Deadenylation of mRNA R-HSA-429947 6.427991e-01 0.192 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 6.427991e-01 0.192 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 6.428050e-01 0.192 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 6.428492e-01 0.192 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 6.428492e-01 0.192 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 6.428492e-01 0.192 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 6.428492e-01 0.192 0 0
G2 Phase R-HSA-68911 6.428492e-01 0.192 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.428492e-01 0.192 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 6.428492e-01 0.192 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 6.428492e-01 0.192 0 0
PTK6 Activates STAT3 R-HSA-8849474 6.428492e-01 0.192 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 6.428492e-01 0.192 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 6.428492e-01 0.192 0 0
NTRK2 activates RAC1 R-HSA-9032759 6.428492e-01 0.192 0 0
Muscarinic acetylcholine receptors R-HSA-390648 6.428492e-01 0.192 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 6.428492e-01 0.192 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 6.428492e-01 0.192 0 0
Toxicity of botulinum toxin type C (botC) R-HSA-5250971 6.428492e-01 0.192 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 6.428492e-01 0.192 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 6.428492e-01 0.192 0 0
Rab regulation of trafficking R-HSA-9007101 6.448782e-01 0.191 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 6.469781e-01 0.189 0 0
ERKs are inactivated R-HSA-202670 6.469781e-01 0.189 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 6.469781e-01 0.189 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 6.469781e-01 0.189 0 0
Integration of provirus R-HSA-162592 6.469781e-01 0.189 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 6.469781e-01 0.189 0 0
Negative regulation of TCF-dependent signaling by WNT ligand antagonists R-HSA-3772470 6.469781e-01 0.189 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 6.469781e-01 0.189 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 6.469781e-01 0.189 0 0
DNA strand elongation R-HSA-69190 6.563179e-01 0.183 0 0
GAB1 signalosome R-HSA-180292 6.570111e-01 0.182 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 6.570111e-01 0.182 0 0
Mismatch Repair R-HSA-5358508 6.570111e-01 0.182 0 0
Chaperone Mediated Autophagy R-HSA-9613829 6.570111e-01 0.182 0 0
Toll-like Receptor Cascades R-HSA-168898 6.580125e-01 0.182 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 6.611810e-01 0.180 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 6.611810e-01 0.180 0 0
DAG and IP3 signaling R-HSA-1489509 6.611810e-01 0.180 0 0
Potential therapeutics for SARS R-HSA-9679191 6.624161e-01 0.179 0 0
Glycolysis R-HSA-70171 6.626002e-01 0.179 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 6.649647e-01 0.177 0 0
Interleukin-7 signaling R-HSA-1266695 6.677514e-01 0.175 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 6.685473e-01 0.175 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 6.730487e-01 0.172 0 0
Co-inhibition by PD-1 R-HSA-389948 6.763191e-01 0.170 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 6.782272e-01 0.169 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 6.813028e-01 0.167 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 6.813028e-01 0.167 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 6.813028e-01 0.167 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 6.813028e-01 0.167 0 0
GRB2 events in EGFR signaling R-HSA-179812 6.813028e-01 0.167 0 0
p75NTR recruits signalling complexes R-HSA-209543 6.813028e-01 0.167 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 6.813028e-01 0.167 0 0
Interleukin-35 Signalling R-HSA-8984722 6.813028e-01 0.167 0 0
Pervasive developmental disorders R-HSA-9005895 6.813028e-01 0.167 0 0
Disorders of Nervous System Development R-HSA-9697154 6.813028e-01 0.167 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 6.813028e-01 0.167 0 0
SARS-CoV-2-host interactions R-HSA-9705683 6.825766e-01 0.166 0 0
Regulation of signaling by CBL R-HSA-912631 6.847428e-01 0.164 0 0
Maturation of nucleoprotein R-HSA-9694631 6.847428e-01 0.164 0 0
Cytoprotection by HMOX1 R-HSA-9707564 6.850558e-01 0.164 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 6.882130e-01 0.162 0 0
Generation of second messenger molecules R-HSA-202433 6.882130e-01 0.162 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 6.882130e-01 0.162 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 6.914801e-01 0.160 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 6.914801e-01 0.160 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 6.917114e-01 0.160 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 6.917114e-01 0.160 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 6.917114e-01 0.160 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 6.917114e-01 0.160 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 6.917114e-01 0.160 0 0
Loss-of-function mutations in DLD cause MSUD3/DLDD R-HSA-9907570 6.917114e-01 0.160 0 0
Loss-of-function mutations in DBT cause MSUD2 R-HSA-9865113 6.917114e-01 0.160 0 0
Ligand-receptor interactions R-HSA-5632681 6.917114e-01 0.160 0 0
Synthesis of PS R-HSA-1483101 6.917114e-01 0.160 0 0
Sensory perception of salty taste R-HSA-9730628 6.917114e-01 0.160 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 6.917114e-01 0.160 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 6.917114e-01 0.160 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 6.917114e-01 0.160 0 0
Relaxin receptors R-HSA-444821 6.917114e-01 0.160 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 6.917114e-01 0.160 0 0
Release of Hh-Np from the secreting cell R-HSA-5362798 6.917114e-01 0.160 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 6.925547e-01 0.160 0 0
Chromosome Maintenance R-HSA-73886 6.925547e-01 0.160 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 6.940696e-01 0.159 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 6.945599e-01 0.158 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.989066e-01 0.156 0 0
Striated Muscle Contraction R-HSA-390522 6.991826e-01 0.155 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 6.997947e-01 0.155 0 0
Co-inhibition by CTLA4 R-HSA-389513 7.107627e-01 0.148 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 7.107627e-01 0.148 0 0
Creatine metabolism R-HSA-71288 7.107627e-01 0.148 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 7.128459e-01 0.147 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 7.128459e-01 0.147 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 7.128459e-01 0.147 0 0
Interleukin-6 signaling R-HSA-1059683 7.128459e-01 0.147 0 0
Maturation of nucleoprotein R-HSA-9683610 7.128459e-01 0.147 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 7.128459e-01 0.147 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 7.139768e-01 0.146 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 7.139768e-01 0.146 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 7.139768e-01 0.146 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.139768e-01 0.146 0 0
Intraflagellar transport R-HSA-5620924 7.149238e-01 0.146 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 7.191741e-01 0.143 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 7.191741e-01 0.143 0 0
IGF1R signaling cascade R-HSA-2428924 7.299303e-01 0.137 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 7.299303e-01 0.137 1 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 7.329859e-01 0.135 0 0
EPH-Ephrin signaling R-HSA-2682334 7.331326e-01 0.135 0 0
Reproduction R-HSA-1474165 7.333193e-01 0.135 0 0
Signaling by LTK in cancer R-HSA-9842640 7.338912e-01 0.134 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 7.338912e-01 0.134 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 7.338912e-01 0.134 0 0
Erythropoietin activates STAT5 R-HSA-9027283 7.338912e-01 0.134 0 0
STAT5 Activation R-HSA-9645135 7.338912e-01 0.134 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 7.338912e-01 0.134 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 7.338912e-01 0.134 0 0
Branched-chain ketoacid dehydrogenase kinase deficiency R-HSA-9912481 7.338912e-01 0.134 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 7.338912e-01 0.134 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 7.338912e-01 0.134 0 0
Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD R-HSA-9865125 7.338912e-01 0.134 0 0
Defective factor VIII causes hemophilia A R-HSA-9662001 7.338912e-01 0.134 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 7.350951e-01 0.134 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 7.350951e-01 0.134 0 0
Early Phase of HIV Life Cycle R-HSA-162594 7.350951e-01 0.134 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 7.352446e-01 0.134 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 7.352446e-01 0.134 0 0
Formation of the Early Elongation Complex R-HSA-113418 7.352446e-01 0.134 0 0
Nucleotide Excision Repair R-HSA-5696398 7.361797e-01 0.133 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 7.370437e-01 0.133 0 0
CRMPs in Sema3A signaling R-HSA-399956 7.417261e-01 0.130 0 0
Prolactin receptor signaling R-HSA-1170546 7.417261e-01 0.130 0 0
NRIF signals cell death from the nucleus R-HSA-205043 7.417261e-01 0.130 0 0
Physiological factors R-HSA-5578768 7.417261e-01 0.130 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 7.417261e-01 0.130 0 0
Cellular response to hypoxia R-HSA-1234174 7.442144e-01 0.128 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 7.442144e-01 0.128 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 7.447330e-01 0.128 0 0
Cell-cell junction organization R-HSA-421270 7.523464e-01 0.124 0 0
Platelet calcium homeostasis R-HSA-418360 7.552968e-01 0.122 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 7.562631e-01 0.121 0 0
RNA Polymerase III Transcription R-HSA-74158 7.562631e-01 0.121 0 0
Regulation of TP53 Degradation R-HSA-6804757 7.562631e-01 0.121 0 0
Calmodulin induced events R-HSA-111933 7.562631e-01 0.121 0 0
CaM pathway R-HSA-111997 7.562631e-01 0.121 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 7.577792e-01 0.120 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 7.577792e-01 0.120 0 0
Assembly Of The HIV Virion R-HSA-175474 7.577792e-01 0.120 0 0
TBC/RABGAPs R-HSA-8854214 7.589666e-01 0.120 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 7.626067e-01 0.118 0 0
HSF1-dependent transactivation R-HSA-3371571 7.626067e-01 0.118 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 7.667642e-01 0.115 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 7.680815e-01 0.115 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 7.680815e-01 0.115 0 0
G beta:gamma signalling through BTK R-HSA-8964315 7.680815e-01 0.115 0 0
p75NTR signals via NF-kB R-HSA-193639 7.680815e-01 0.115 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 7.680815e-01 0.115 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 7.680815e-01 0.115 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 7.680815e-01 0.115 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 7.680815e-01 0.115 0 0
Other semaphorin interactions R-HSA-416700 7.680815e-01 0.115 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 7.703021e-01 0.113 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 7.703021e-01 0.113 0 0
Disinhibition of SNARE formation R-HSA-114516 7.703021e-01 0.113 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 7.703021e-01 0.113 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 7.703021e-01 0.113 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 7.703021e-01 0.113 0 0
TRIF-mediated programmed cell death R-HSA-2562578 7.703021e-01 0.113 0 0
VLDL clearance R-HSA-8964046 7.703021e-01 0.113 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 7.703021e-01 0.113 0 0
CHL1 interactions R-HSA-447041 7.703021e-01 0.113 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 7.703021e-01 0.113 0 0
Kidney development R-HSA-9830369 7.712025e-01 0.113 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.741552e-01 0.111 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.741552e-01 0.111 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 7.771455e-01 0.109 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.771455e-01 0.109 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 7.788662e-01 0.109 0 0
FGFR2 alternative splicing R-HSA-6803529 7.788662e-01 0.109 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 7.788662e-01 0.109 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 7.788662e-01 0.109 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 7.788662e-01 0.109 0 0
Signaling by KIT in disease R-HSA-9669938 7.788662e-01 0.109 0 0
Cytokine Signaling in Immune system R-HSA-1280215 7.801731e-01 0.108 0 0
PPARA activates gene expression R-HSA-1989781 7.803233e-01 0.108 0 0
Base Excision Repair R-HSA-73884 7.850392e-01 0.105 0 0
Fanconi Anemia Pathway R-HSA-6783310 7.895946e-01 0.103 0 0
Smooth Muscle Contraction R-HSA-445355 7.910145e-01 0.102 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 7.920621e-01 0.101 0 0
Phosphorylation of the APC/C R-HSA-176412 7.920621e-01 0.101 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 7.920621e-01 0.101 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 7.920621e-01 0.101 0 0
Formation of paraxial mesoderm R-HSA-9793380 7.932844e-01 0.101 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.941558e-01 0.100 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 7.984165e-01 0.098 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 7.984165e-01 0.098 0 0
Telomere Maintenance R-HSA-157579 7.998327e-01 0.097 0 0
Activation of RAS in B cells R-HSA-1169092 8.017328e-01 0.096 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 8.017328e-01 0.096 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 8.017328e-01 0.096 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 8.017328e-01 0.096 0 0
Adrenoceptors R-HSA-390696 8.017328e-01 0.096 0 0
Interleukin-9 signaling R-HSA-8985947 8.017328e-01 0.096 0 0
TGFBR3 PTM regulation R-HSA-9839383 8.017328e-01 0.096 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 8.017328e-01 0.096 0 0
Alpha-defensins R-HSA-1462054 8.017328e-01 0.096 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 8.017328e-01 0.096 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 8.017328e-01 0.096 0 0
Plasma lipoprotein clearance R-HSA-8964043 8.048142e-01 0.094 0 0
COPII-mediated vesicle transport R-HSA-204005 8.077593e-01 0.093 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 8.084107e-01 0.092 0 0
Signaling by FGFR R-HSA-190236 8.096750e-01 0.092 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 8.138243e-01 0.089 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 8.138243e-01 0.089 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 8.138243e-01 0.089 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 8.138243e-01 0.089 0 0
tRNA modification in the mitochondrion R-HSA-6787450 8.138243e-01 0.089 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 8.164975e-01 0.088 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 8.164975e-01 0.088 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.191843e-01 0.087 0 0
Insulin receptor signalling cascade R-HSA-74751 8.287437e-01 0.082 0 0
MAPK1 (ERK2) activation R-HSA-112411 8.288642e-01 0.082 0 0
ALK mutants bind TKIs R-HSA-9700645 8.288642e-01 0.082 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 8.288642e-01 0.082 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 8.288642e-01 0.082 0 0
Unwinding of DNA R-HSA-176974 8.288642e-01 0.082 0 0
mRNA Editing R-HSA-75072 8.288642e-01 0.082 0 0
Regulation of signaling by NODAL R-HSA-1433617 8.288642e-01 0.082 0 0
Lipophagy R-HSA-9613354 8.288642e-01 0.082 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 8.288642e-01 0.082 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 8.288642e-01 0.082 0 0
GPER1 signaling R-HSA-9634597 8.298256e-01 0.081 0 0
Co-stimulation by CD28 R-HSA-389356 8.298256e-01 0.081 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 8.321545e-01 0.080 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 8.326898e-01 0.080 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 8.331808e-01 0.079 0 0
G protein gated Potassium channels R-HSA-1296059 8.331808e-01 0.079 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 8.331808e-01 0.079 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 8.331808e-01 0.079 0 0
Acyl chain remodelling of PS R-HSA-1482801 8.331808e-01 0.079 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 8.335261e-01 0.079 0 0
Glycogen storage diseases R-HSA-3229121 8.335261e-01 0.079 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 8.335261e-01 0.079 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 8.335261e-01 0.079 0 0
Specification of primordial germ cells R-HSA-9827857 8.335261e-01 0.079 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.335261e-01 0.079 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.370646e-01 0.077 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 8.383032e-01 0.077 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.383032e-01 0.077 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 8.485413e-01 0.071 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 8.485413e-01 0.071 0 0
HCMV Late Events R-HSA-9610379 8.512593e-01 0.070 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 8.513238e-01 0.070 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 8.513238e-01 0.070 0 0
PKA activation in glucagon signalling R-HSA-164378 8.513238e-01 0.070 0 0
PKA activation R-HSA-163615 8.513238e-01 0.070 0 0
Apoptotic factor-mediated response R-HSA-111471 8.513238e-01 0.070 0 0
Synaptic adhesion-like molecules R-HSA-8849932 8.513238e-01 0.070 0 0
Platelet sensitization by LDL R-HSA-432142 8.513238e-01 0.070 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 8.513238e-01 0.070 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 8.517211e-01 0.070 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 8.517211e-01 0.070 0 0
NOD1/2 Signaling Pathway R-HSA-168638 8.517211e-01 0.070 1 1
Apoptosis induced DNA fragmentation R-HSA-140342 8.522843e-01 0.069 0 0
Serotonin receptors R-HSA-390666 8.522843e-01 0.069 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 8.522843e-01 0.069 0 0
Arachidonate production from DAG R-HSA-426048 8.522843e-01 0.069 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 8.522843e-01 0.069 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 8.522843e-01 0.069 0 0
Interleukin-27 signaling R-HSA-9020956 8.522843e-01 0.069 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 8.522843e-01 0.069 0 0
Sperm Motility And Taxes R-HSA-1300642 8.522843e-01 0.069 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 8.522843e-01 0.069 0 0
Josephin domain DUBs R-HSA-5689877 8.522843e-01 0.069 0 0
Regulation of CDH11 function R-HSA-9762292 8.522843e-01 0.069 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.530514e-01 0.069 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 8.566981e-01 0.067 0 0
Ca-dependent events R-HSA-111996 8.572268e-01 0.067 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 8.572268e-01 0.067 0 0
Depyrimidination R-HSA-73928 8.572268e-01 0.067 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 8.586406e-01 0.066 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 8.626553e-01 0.064 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 8.626553e-01 0.064 0 0
Packaging Of Telomere Ends R-HSA-171306 8.626553e-01 0.064 0 0
Cristae formation R-HSA-8949613 8.626553e-01 0.064 0 0
Signaling by BMP R-HSA-201451 8.626553e-01 0.064 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 8.626553e-01 0.064 0 0
Insulin processing R-HSA-264876 8.626553e-01 0.064 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 8.641819e-01 0.063 0 0
Glucose metabolism R-HSA-70326 8.643678e-01 0.063 0 0
Signaling by Interleukins R-HSA-449147 8.650192e-01 0.063 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 8.673694e-01 0.062 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 8.673694e-01 0.062 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 8.673694e-01 0.062 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 8.673694e-01 0.062 0 0
Specification of the neural plate border R-HSA-9834899 8.673694e-01 0.062 0 0
The NLRP3 inflammasome R-HSA-844456 8.673694e-01 0.062 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 8.673694e-01 0.062 0 0
STING mediated induction of host immune responses R-HSA-1834941 8.673694e-01 0.062 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 8.673694e-01 0.062 0 0
Diseases of hemostasis R-HSA-9671793 8.673694e-01 0.062 0 0
Other interleukin signaling R-HSA-449836 8.673694e-01 0.062 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 8.673694e-01 0.062 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 8.673990e-01 0.062 0 0
RSV-host interactions R-HSA-9833110 8.687847e-01 0.061 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.699287e-01 0.061 0 0
Transmission across Chemical Synapses R-HSA-112315 8.723632e-01 0.059 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 8.725004e-01 0.059 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 8.725004e-01 0.059 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 8.725004e-01 0.059 0 0
vRNA Synthesis R-HSA-192814 8.725004e-01 0.059 0 0
Regulation of gene expression in early pancreatic precursor cells R-HSA-210747 8.725004e-01 0.059 0 0
Bicarbonate transporters R-HSA-425381 8.725004e-01 0.059 0 0
Transport of RCbl within the body R-HSA-9758890 8.725004e-01 0.059 0 0
LGI-ADAM interactions R-HSA-5682910 8.725004e-01 0.059 0 0
Inorganic anion exchange by SLC26 transporters R-HSA-427601 8.725004e-01 0.059 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 8.725004e-01 0.059 0 0
Dissolution of Fibrin Clot R-HSA-75205 8.725004e-01 0.059 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.755992e-01 0.058 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 8.757338e-01 0.058 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 8.818091e-01 0.055 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 8.818091e-01 0.055 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 8.818091e-01 0.055 0 0
Negative regulation of MET activity R-HSA-6807004 8.818091e-01 0.055 0 0
Glycogen synthesis R-HSA-3322077 8.818091e-01 0.055 0 0
RNA Polymerase I Transcription R-HSA-73864 8.835976e-01 0.054 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 8.850536e-01 0.053 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 8.864252e-01 0.052 0 0
Cleavage of the damaged purine R-HSA-110331 8.864252e-01 0.052 0 0
Collagen chain trimerization R-HSA-8948216 8.864252e-01 0.052 0 0
mRNA Capping R-HSA-72086 8.874488e-01 0.052 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 8.874488e-01 0.052 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 8.874488e-01 0.052 0 0
DARPP-32 events R-HSA-180024 8.874488e-01 0.052 0 0
Signaling by PDGF R-HSA-186797 8.878415e-01 0.052 0 0
Nucleosome assembly R-HSA-774815 8.883356e-01 0.051 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.883356e-01 0.051 0 0
Plasmalogen biosynthesis R-HSA-75896 8.899508e-01 0.051 0 0
NF-kB is activated and signals survival R-HSA-209560 8.899508e-01 0.051 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 8.899508e-01 0.051 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 8.899508e-01 0.051 0 0
Anchoring fibril formation R-HSA-2214320 8.899508e-01 0.051 0 0
DS-GAG biosynthesis R-HSA-2022923 8.899508e-01 0.051 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 8.917068e-01 0.050 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 8.947818e-01 0.048 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 8.947818e-01 0.048 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 8.947818e-01 0.048 0 0
Basigin interactions R-HSA-210991 8.947818e-01 0.048 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.963044e-01 0.048 0 0
Depurination R-HSA-73927 8.963044e-01 0.048 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 8.981313e-01 0.047 0 0
G alpha (z) signalling events R-HSA-418597 8.998954e-01 0.046 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 9.002507e-01 0.046 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 9.016508e-01 0.045 0 0
Ub-specific processing proteases R-HSA-5689880 9.029310e-01 0.044 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 9.050138e-01 0.043 0 0
Maple Syrup Urine Disease R-HSA-9865114 9.050138e-01 0.043 0 0
IRAK1 recruits IKK complex R-HSA-937039 9.050138e-01 0.043 0 0
Scavenging by Class F Receptors R-HSA-3000484 9.050138e-01 0.043 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 9.050138e-01 0.043 0 0
Regulation of IFNG signaling R-HSA-877312 9.050138e-01 0.043 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 9.050138e-01 0.043 0 0
OAS antiviral response R-HSA-8983711 9.050138e-01 0.043 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 9.054191e-01 0.043 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 9.064186e-01 0.043 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 9.064186e-01 0.043 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 9.064186e-01 0.043 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.071099e-01 0.042 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 9.075467e-01 0.042 0 0
Ion homeostasis R-HSA-5578775 9.075467e-01 0.042 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.128974e-01 0.040 0 0
Attenuation phase R-HSA-3371568 9.138163e-01 0.039 0 0
HIV Transcription Elongation R-HSA-167169 9.138163e-01 0.039 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 9.138163e-01 0.039 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 9.138163e-01 0.039 0 0
IRS-mediated signalling R-HSA-112399 9.146869e-01 0.039 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.168420e-01 0.038 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 9.168420e-01 0.038 0 0
Inwardly rectifying K+ channels R-HSA-1296065 9.171621e-01 0.038 0 0
Adenylate cyclase activating pathway R-HSA-170660 9.180157e-01 0.037 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 9.180157e-01 0.037 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 9.180157e-01 0.037 0 0
Processing of SMDT1 R-HSA-8949664 9.180157e-01 0.037 0 0
Cellular response to chemical stress R-HSA-9711123 9.189477e-01 0.037 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.196306e-01 0.036 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.206153e-01 0.036 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.206153e-01 0.036 0 0
DNA Damage Bypass R-HSA-73893 9.206153e-01 0.036 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 9.215417e-01 0.035 0 0
G-protein beta:gamma signalling R-HSA-397795 9.253524e-01 0.034 0 0
Regulation of necroptotic cell death R-HSA-5675482 9.253524e-01 0.034 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 9.261660e-01 0.033 0 0
Interleukin-20 family signaling R-HSA-8854691 9.261660e-01 0.033 0 0
Carnitine shuttle R-HSA-200425 9.261660e-01 0.033 0 0
Syndecan interactions R-HSA-3000170 9.261660e-01 0.033 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.261660e-01 0.033 0 0
Formation of the ureteric bud R-HSA-9830674 9.261660e-01 0.033 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 9.269163e-01 0.033 0 0
Regulation of RAS by GAPs R-HSA-5658442 9.272692e-01 0.033 0 0
PI3K Cascade R-HSA-109704 9.272692e-01 0.033 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.275379e-01 0.033 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.286395e-01 0.032 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.286395e-01 0.032 0 0
Intra-Golgi traffic R-HSA-6811438 9.286395e-01 0.032 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 9.292385e-01 0.032 0 0
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV R-HSA-9859138 9.292385e-01 0.032 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 9.292385e-01 0.032 0 0
cGMP effects R-HSA-418457 9.292385e-01 0.032 0 0
Malate-aspartate shuttle R-HSA-9856872 9.292385e-01 0.032 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 9.292385e-01 0.032 0 0
HDL assembly R-HSA-8963896 9.292385e-01 0.032 0 0
P2Y receptors R-HSA-417957 9.292385e-01 0.032 0 0
SARS-CoV Infections R-HSA-9679506 9.308850e-01 0.031 0 0
Synthesis of DNA R-HSA-69239 9.322927e-01 0.030 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 9.327935e-01 0.030 0 0
Complex III assembly R-HSA-9865881 9.344964e-01 0.029 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 9.344964e-01 0.029 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.344964e-01 0.029 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 9.344964e-01 0.029 0 0
Interleukin-6 family signaling R-HSA-6783589 9.344964e-01 0.029 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.344964e-01 0.029 0 0
GABA B receptor activation R-HSA-977444 9.351522e-01 0.029 0 0
Activation of GABAB receptors R-HSA-991365 9.351522e-01 0.029 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.386514e-01 0.027 0 0
Collagen degradation R-HSA-1442490 9.386514e-01 0.027 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 9.389256e-01 0.027 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 9.389256e-01 0.027 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 9.389256e-01 0.027 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 9.389256e-01 0.027 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 9.389256e-01 0.027 0 0
Translesion synthesis by REV1 R-HSA-110312 9.389256e-01 0.027 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 9.389256e-01 0.027 0 0
FASTK family proteins regulate processing and stability of mitochondrial RNAs R-HSA-9837092 9.389256e-01 0.027 0 0
Protein lipoylation R-HSA-9857492 9.389256e-01 0.027 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 9.389256e-01 0.027 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 9.389256e-01 0.027 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 9.391048e-01 0.027 0 0
Dual Incision in GG-NER R-HSA-5696400 9.395453e-01 0.027 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 9.395453e-01 0.027 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.409933e-01 0.026 0 0
Defective pyroptosis R-HSA-9710421 9.411208e-01 0.026 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.419303e-01 0.026 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 9.419303e-01 0.026 0 0
Laminin interactions R-HSA-3000157 9.419303e-01 0.026 0 0
Formation of the nephric duct R-HSA-9830364 9.419303e-01 0.026 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.419303e-01 0.026 0 0
Hyaluronan degradation R-HSA-2160916 9.419303e-01 0.026 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 9.443474e-01 0.025 0 0
Amine ligand-binding receptors R-HSA-375280 9.465843e-01 0.024 0 0
Surfactant metabolism R-HSA-5683826 9.465843e-01 0.024 0 0
Translesion synthesis by POLI R-HSA-5656121 9.472871e-01 0.024 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 9.472871e-01 0.024 0 0
Phase 4 - resting membrane potential R-HSA-5576886 9.472871e-01 0.024 0 0
Regulation of BACH1 activity R-HSA-9708530 9.472871e-01 0.024 0 0
Fructose catabolism R-HSA-70350 9.472871e-01 0.024 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 9.472871e-01 0.024 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 9.472871e-01 0.024 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 9.482206e-01 0.023 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.485570e-01 0.023 0 0
TRP channels R-HSA-3295583 9.485570e-01 0.023 0 0
Metalloprotease DUBs R-HSA-5689901 9.485570e-01 0.023 0 0
MET activates PTK2 signaling R-HSA-8874081 9.485570e-01 0.023 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.491786e-01 0.023 0 0
HSF1 activation R-HSA-3371511 9.512026e-01 0.022 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.512026e-01 0.022 0 0
Glycosphingolipid transport R-HSA-9845576 9.512026e-01 0.022 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 9.544582e-01 0.020 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 9.544582e-01 0.020 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.544582e-01 0.020 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.544582e-01 0.020 0 0
Translesion synthesis by POLK R-HSA-5655862 9.545042e-01 0.020 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 9.545042e-01 0.020 0 0
Coenzyme A biosynthesis R-HSA-196783 9.545042e-01 0.020 0 0
Fibronectin matrix formation R-HSA-1566977 9.545042e-01 0.020 0 0
Synthesis of PG R-HSA-1483148 9.545042e-01 0.020 0 0
Scavenging by Class B Receptors R-HSA-3000471 9.545042e-01 0.020 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 9.545042e-01 0.020 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 9.545042e-01 0.020 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 9.545042e-01 0.020 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.551144e-01 0.020 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 9.561419e-01 0.019 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.562105e-01 0.019 0 0
Degradation of DVL R-HSA-4641258 9.562105e-01 0.019 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 9.595182e-01 0.018 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 9.595636e-01 0.018 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 9.597083e-01 0.018 0 0
Pyrimidine salvage R-HSA-73614 9.597083e-01 0.018 0 0
Pyroptosis R-HSA-5620971 9.597083e-01 0.018 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 9.607336e-01 0.017 0 0
Sulfide oxidation to sulfate R-HSA-1614517 9.607336e-01 0.017 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 9.607336e-01 0.017 0 0
Catecholamine biosynthesis R-HSA-209905 9.607336e-01 0.017 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 9.607336e-01 0.017 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.607336e-01 0.017 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 9.607336e-01 0.017 0 0
Synthesis of PA R-HSA-1483166 9.614730e-01 0.017 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.628672e-01 0.016 0 0
Interleukin-1 family signaling R-HSA-446652 9.629715e-01 0.016 0 0
Developmental Cell Lineages R-HSA-9734767 9.639063e-01 0.016 0 0
Metal ion SLC transporters R-HSA-425410 9.640980e-01 0.016 0 0
Termination of translesion DNA synthesis R-HSA-5656169 9.643749e-01 0.016 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.643749e-01 0.016 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.644300e-01 0.016 0 0
Dual incision in TC-NER R-HSA-6782135 9.649213e-01 0.016 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 9.661103e-01 0.015 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 9.661103e-01 0.015 0 0
Presynaptic function of Kainate receptors R-HSA-500657 9.661103e-01 0.015 0 0
Biosynthesis of Lipoxins (LX) R-HSA-2142700 9.661103e-01 0.015 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 9.661103e-01 0.015 0 0
PCP/CE pathway R-HSA-4086400 9.685432e-01 0.014 0 0
Influenza Infection R-HSA-168255 9.695874e-01 0.013 0 0
Crosslinking of collagen fibrils R-HSA-2243919 9.707511e-01 0.013 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 9.707511e-01 0.013 0 0
Pyrimidine biosynthesis R-HSA-500753 9.707511e-01 0.013 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.709797e-01 0.013 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 9.716068e-01 0.013 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 9.718065e-01 0.012 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 9.718065e-01 0.012 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.720334e-01 0.012 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.720334e-01 0.012 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 9.721970e-01 0.012 0 0
Meiotic recombination R-HSA-912446 9.735502e-01 0.012 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.736308e-01 0.012 0 0
PLC beta mediated events R-HSA-112043 9.736308e-01 0.012 0 0
Platelet degranulation R-HSA-114608 9.745151e-01 0.011 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.747566e-01 0.011 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 9.747566e-01 0.011 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 9.747566e-01 0.011 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 9.747566e-01 0.011 0 0
Pregnenolone biosynthesis R-HSA-196108 9.747566e-01 0.011 0 0
Protein hydroxylation R-HSA-9629569 9.747566e-01 0.011 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.747874e-01 0.011 0 0
Heme biosynthesis R-HSA-189451 9.747874e-01 0.011 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 9.749618e-01 0.011 0 0
Orc1 removal from chromatin R-HSA-68949 9.761433e-01 0.010 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.774672e-01 0.010 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.774672e-01 0.010 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 9.782138e-01 0.010 0 0
G-protein activation R-HSA-202040 9.782138e-01 0.010 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 9.782138e-01 0.010 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 9.783477e-01 0.010 0 0
Recycling of bile acids and salts R-HSA-159418 9.783477e-01 0.010 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.791435e-01 0.009 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.798743e-01 0.009 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.806283e-01 0.008 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.809063e-01 0.008 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.811976e-01 0.008 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 9.811976e-01 0.008 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 9.811976e-01 0.008 0 0
Mitochondrial calcium ion transport R-HSA-8949215 9.811976e-01 0.008 0 0
Stimuli-sensing channels R-HSA-2672351 9.817195e-01 0.008 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.820347e-01 0.008 0 0
Signaling by Insulin receptor R-HSA-74752 9.822542e-01 0.008 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 9.831704e-01 0.007 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.831704e-01 0.007 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.831704e-01 0.007 0 0
Hyaluronan metabolism R-HSA-2142845 9.831704e-01 0.007 0 0
Mitophagy R-HSA-5205647 9.831704e-01 0.007 0 0
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy R-HSA-9857377 9.837730e-01 0.007 0 0
Fructose metabolism R-HSA-5652084 9.837730e-01 0.007 0 0
Ethanol oxidation R-HSA-71384 9.837730e-01 0.007 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 9.837730e-01 0.007 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.839723e-01 0.007 0 0
Somitogenesis R-HSA-9824272 9.839723e-01 0.007 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 9.839723e-01 0.007 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.843718e-01 0.007 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 9.847975e-01 0.007 0 0
G-protein mediated events R-HSA-112040 9.853516e-01 0.006 0 0
SLC transporter disorders R-HSA-5619102 9.858208e-01 0.006 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 9.859957e-01 0.006 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 9.859957e-01 0.006 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.859957e-01 0.006 0 0
Organic anion transport by SLCO transporters R-HSA-879518 9.859957e-01 0.006 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.867459e-01 0.006 0 0
Regulated Necrosis R-HSA-5218859 9.867459e-01 0.006 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.869424e-01 0.006 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 9.869908e-01 0.006 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.872638e-01 0.006 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.878942e-01 0.005 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.879141e-01 0.005 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.879141e-01 0.005 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.879141e-01 0.005 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 9.879141e-01 0.005 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.879141e-01 0.005 0 0
Signaling by ROBO receptors R-HSA-376176 9.882860e-01 0.005 0 0
Peroxisomal protein import R-HSA-9033241 9.886083e-01 0.005 0 0
DNA Replication R-HSA-69306 9.887652e-01 0.005 0 0
Tight junction interactions R-HSA-420029 9.895698e-01 0.005 0 0
Defects in cobalamin (B12) metabolism R-HSA-3296469 9.895698e-01 0.005 0 0
Beta-oxidation of pristanoyl-CoA R-HSA-389887 9.895698e-01 0.005 0 0
Fertilization R-HSA-1187000 9.895698e-01 0.005 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.895698e-01 0.005 0 0
GABA receptor activation R-HSA-977443 9.897727e-01 0.004 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.897727e-01 0.004 0 0
Degradation of CDH1 R-HSA-9766229 9.899001e-01 0.004 0 0
Platelet homeostasis R-HSA-418346 9.899077e-01 0.004 0 0
SARS-CoV-1-host interactions R-HSA-9692914 9.899077e-01 0.004 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 9.902138e-01 0.004 0 0
Regulation of mitotic cell cycle R-HSA-453276 9.902138e-01 0.004 0 0
Formation of the cornified envelope R-HSA-6809371 9.909949e-01 0.004 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 9.909987e-01 0.004 0 0
Attachment of bacteria to epithelial cells R-HSA-9638630 9.909987e-01 0.004 0 0
Urea cycle R-HSA-70635 9.909987e-01 0.004 0 0
Sphingolipid catabolism R-HSA-9845614 9.909987e-01 0.004 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.909987e-01 0.004 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.911034e-01 0.004 0 0
Stabilization of p53 R-HSA-69541 9.911034e-01 0.004 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.911034e-01 0.004 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.911034e-01 0.004 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.915217e-01 0.004 0 0
Leishmania phagocytosis R-HSA-9664417 9.915217e-01 0.004 0 0
Parasite infection R-HSA-9664407 9.915217e-01 0.004 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.920063e-01 0.003 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 9.921774e-01 0.003 0 0
Glycogen metabolism R-HSA-8982491 9.921774e-01 0.003 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.921774e-01 0.003 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.922040e-01 0.003 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.922320e-01 0.003 0 0
Cobalamin (Cbl) metabolism R-HSA-9759218 9.922320e-01 0.003 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 9.922320e-01 0.003 0 0
Synthesis of PE R-HSA-1483213 9.922320e-01 0.003 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.931242e-01 0.003 0 0
Maturation of spike protein R-HSA-9694548 9.931242e-01 0.003 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.932924e-01 0.003 0 0
Phospholipid metabolism R-HSA-1483257 9.933659e-01 0.003 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.936848e-01 0.003 0 0
Nucleotide biosynthesis R-HSA-8956320 9.936848e-01 0.003 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.936848e-01 0.003 0 0
Collagen formation R-HSA-1474290 9.937912e-01 0.003 0 0
Muscle contraction R-HSA-397014 9.938777e-01 0.003 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.939585e-01 0.003 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.939585e-01 0.003 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.939585e-01 0.003 0 0
Translation of Structural Proteins R-HSA-9683701 9.939585e-01 0.003 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 9.940025e-01 0.003 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 9.940025e-01 0.003 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 9.942096e-01 0.003 0 0
DNA methylation R-HSA-5334118 9.942149e-01 0.003 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.942149e-01 0.003 0 0
Glucagon-type ligand receptors R-HSA-420092 9.942149e-01 0.003 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 9.943298e-01 0.002 0 0
Integration of energy metabolism R-HSA-163685 9.943443e-01 0.002 0 0
Opioid Signalling R-HSA-111885 9.943845e-01 0.002 0 0
Translation initiation complex formation R-HSA-72649 9.943905e-01 0.002 0 0
Neuronal System R-HSA-112316 9.946475e-01 0.002 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.947003e-01 0.002 0 0
Translation of Structural Proteins R-HSA-9694635 9.947375e-01 0.002 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.950076e-01 0.002 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.950076e-01 0.002 0 0
Neurotransmitter clearance R-HSA-112311 9.950076e-01 0.002 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.950076e-01 0.002 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 9.950194e-01 0.002 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.953402e-01 0.002 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 9.955796e-01 0.002 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 9.955796e-01 0.002 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.955796e-01 0.002 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.956918e-01 0.002 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.956918e-01 0.002 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.959095e-01 0.002 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.959095e-01 0.002 0 0
Regulation of CDH1 Function R-HSA-9764561 9.960784e-01 0.002 0 0
Regulation of insulin secretion R-HSA-422356 9.961557e-01 0.002 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.961597e-01 0.002 0 0
Neurotransmitter release cycle R-HSA-112310 9.962898e-01 0.002 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.964104e-01 0.002 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 9.965222e-01 0.002 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 9.966119e-01 0.001 0 0
Neddylation R-HSA-8951664 9.966792e-01 0.001 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.968508e-01 0.001 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.968508e-01 0.001 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.968508e-01 0.001 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.969717e-01 0.001 0 0
Adaptive Immune System R-HSA-1280218 9.971003e-01 0.001 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.972315e-01 0.001 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.972380e-01 0.001 0 0
Synthesis of PC R-HSA-1483191 9.972380e-01 0.001 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.972674e-01 0.001 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.972674e-01 0.001 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.975343e-01 0.001 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.975343e-01 0.001 0 0
Aquaporin-mediated transport R-HSA-445717 9.975798e-01 0.001 0 0
Endogenous sterols R-HSA-211976 9.975798e-01 0.001 0 0
Nucleotide salvage R-HSA-8956321 9.975798e-01 0.001 0 0
eNOS activation R-HSA-203615 9.976110e-01 0.001 0 0
Signal amplification R-HSA-392518 9.976110e-01 0.001 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.976110e-01 0.001 0 0
RA biosynthesis pathway R-HSA-5365859 9.976110e-01 0.001 0 0
Hemostasis R-HSA-109582 9.976409e-01 0.001 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.978569e-01 0.001 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.979385e-01 0.001 0 0
Regulation of Apoptosis R-HSA-169911 9.979385e-01 0.001 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.979385e-01 0.001 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.979385e-01 0.001 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.979385e-01 0.001 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.980808e-01 0.001 0 0
Azathioprine ADME R-HSA-9748787 9.981395e-01 0.001 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.981395e-01 0.001 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.981993e-01 0.001 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.982211e-01 0.001 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 9.982211e-01 0.001 0 0
Triglyceride catabolism R-HSA-163560 9.982211e-01 0.001 0 0
Interferon gamma signaling R-HSA-877300 9.983048e-01 0.001 0 0
Ion transport by P-type ATPases R-HSA-936837 9.983211e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.983219e-01 0.001 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.983718e-01 0.001 0 0
Degradation of AXIN R-HSA-4641257 9.984650e-01 0.001 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.984650e-01 0.001 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.984650e-01 0.001 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.984650e-01 0.001 0 0
Metabolism of folate and pterines R-HSA-196757 9.984650e-01 0.001 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 9.985148e-01 0.001 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.985721e-01 0.001 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 9.985721e-01 0.001 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 9.985721e-01 0.001 0 0
tRNA processing in the mitochondrion R-HSA-6785470 9.986754e-01 0.001 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.986754e-01 0.001 0 0
Elastic fibre formation R-HSA-1566948 9.986754e-01 0.001 0 0
Biofilm formation R-HSA-9931953 9.986754e-01 0.001 0 0
Purine salvage R-HSA-74217 9.986754e-01 0.001 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.987496e-01 0.001 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.988387e-01 0.001 0 0
RAS processing R-HSA-9648002 9.988570e-01 0.000 0 0
TCR signaling R-HSA-202403 9.989464e-01 0.000 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 9.990138e-01 0.000 0 0
Diseases of Immune System R-HSA-5260271 9.990138e-01 0.000 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.990138e-01 0.000 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.990138e-01 0.000 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.991490e-01 0.000 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.991490e-01 0.000 0 0
Cellular response to starvation R-HSA-9711097 9.992002e-01 0.000 0 0
Cardiac conduction R-HSA-5576891 9.992881e-01 0.000 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.992926e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.992926e-01 0.000 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.993580e-01 0.000 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.993664e-01 0.000 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.994034e-01 0.000 0 0
Viral Infection Pathways R-HSA-9824446 9.994299e-01 0.000 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.994385e-01 0.000 0 0
Defensins R-HSA-1461973 9.994533e-01 0.000 0 0
Pyrimidine catabolism R-HSA-73621 9.994533e-01 0.000 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.995137e-01 0.000 0 0
Cap-dependent Translation Initiation R-HSA-72737 9.995392e-01 0.000 0 0
Eukaryotic Translation Initiation R-HSA-72613 9.995392e-01 0.000 0 0
Interleukin-12 family signaling R-HSA-447115 9.995797e-01 0.000 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.995930e-01 0.000 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.995930e-01 0.000 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.995930e-01 0.000 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 9.995938e-01 0.000 0 0
SARS-CoV-1 Infection R-HSA-9678108 9.996125e-01 0.000 0 0
Interleukin-12 signaling R-HSA-9020591 9.996217e-01 0.000 0 0
rRNA processing R-HSA-72312 9.996239e-01 0.000 0 0
Mitochondrial protein import R-HSA-1268020 9.996248e-01 0.000 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.996248e-01 0.000 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 9.996488e-01 0.000 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.996488e-01 0.000 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.996970e-01 0.000 0 0
Parasitic Infection Pathways R-HSA-9824443 9.996985e-01 0.000 0 0
Leishmania infection R-HSA-9658195 9.996985e-01 0.000 0 0
Interleukin-10 signaling R-HSA-6783783 9.997060e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.997060e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.997061e-01 0.000 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.997744e-01 0.000 0 0
G alpha (s) signalling events R-HSA-418555 9.997766e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.998090e-01 0.000 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.998321e-01 0.000 0 0
Complex IV assembly R-HSA-9864848 9.998321e-01 0.000 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.998321e-01 0.000 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.998441e-01 0.000 0 0
Interferon alpha/beta signaling R-HSA-909733 9.998494e-01 0.000 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.998551e-01 0.000 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.998736e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.998796e-01 0.000 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.998799e-01 0.000 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.998842e-01 0.000 0 0
Potassium Channels R-HSA-1296071 9.998881e-01 0.000 0 0
ECM proteoglycans R-HSA-3000178 9.998890e-01 0.000 0 0
Ion channel transport R-HSA-983712 9.998921e-01 0.000 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 9.998931e-01 0.000 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.999031e-01 0.000 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.999065e-01 0.000 0 0
Paracetamol ADME R-HSA-9753281 9.999070e-01 0.000 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.999070e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.999155e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.999197e-01 0.000 0 0
Dectin-2 family R-HSA-5621480 9.999308e-01 0.000 0 0
Protein ubiquitination R-HSA-8852135 9.999357e-01 0.000 0 0
Iron uptake and transport R-HSA-917937 9.999357e-01 0.000 0 0
Interleukin-1 signaling R-HSA-9020702 9.999393e-01 0.000 0 0
Triglyceride metabolism R-HSA-8979227 9.999485e-01 0.000 0 0
tRNA Aminoacylation R-HSA-379724 9.999555e-01 0.000 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.999568e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999630e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.999707e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.999715e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999715e-01 0.000 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.999720e-01 0.000 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.999743e-01 0.000 0 0
Xenobiotics R-HSA-211981 9.999754e-01 0.000 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.999786e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.999802e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.999802e-01 0.000 0 0
Protein localization R-HSA-9609507 9.999808e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.999842e-01 0.000 0 0
Metabolism of steroid hormones R-HSA-196071 9.999842e-01 0.000 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.999847e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.999866e-01 0.000 0 0
ABC-family proteins mediated transport R-HSA-382556 9.999883e-01 0.000 0 0
G alpha (q) signalling events R-HSA-416476 9.999895e-01 0.000 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.999906e-01 0.000 0 0
Peptide chain elongation R-HSA-156902 9.999906e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.999912e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.999912e-01 0.000 0 0
ER-Phagosome pathway R-HSA-1236974 9.999918e-01 0.000 0 0
Downstream TCR signaling R-HSA-202424 9.999929e-01 0.000 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.999938e-01 0.000 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.999953e-01 0.000 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.999964e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999969e-01 0.000 0 0
Integrin cell surface interactions R-HSA-216083 9.999969e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.999969e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999972e-01 0.000 0 0
Eukaryotic Translation Termination R-HSA-72764 9.999973e-01 0.000 0 0
Formation of a pool of free 40S subunits R-HSA-72689 9.999973e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999977e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999979e-01 0.000 0 0
Amyloid fiber formation R-HSA-977225 9.999980e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.999980e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999982e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999982e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.999984e-01 0.000 0 0
Ribosome-associated quality control R-HSA-9948299 9.999984e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999987e-01 0.000 0 0
Selenocysteine synthesis R-HSA-2408557 9.999988e-01 0.000 0 0
Viral mRNA Translation R-HSA-192823 9.999991e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.999992e-01 0.000 0 0
Pyruvate metabolism R-HSA-70268 9.999993e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999993e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999994e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999997e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999997e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999999e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.999999e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.999999e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
Mitochondrial translation R-HSA-5368287 1.000000e+00 0.000 0 0
Nucleotide catabolism R-HSA-8956319 1.000000e+00 0.000 0 0
Respiratory electron transport R-HSA-611105 1.000000e+00 0.000 0 0
Metabolism of nucleotides R-HSA-15869 1.000000e+00 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 1.000000e+00 0.000 0 0
Immune System R-HSA-168256 1.000000e+00 0.000 1 0
Post-translational protein modification R-HSA-597592 1.000000e+00 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Diseases of glycosylation R-HSA-3781865 1.000000e+00 0.000 0 0
Sensory perception of taste R-HSA-9717189 1.000000e+00 0.000 0 0
Neutrophil degranulation R-HSA-6798695 1.000000e+00 0.000 0 0
Infectious disease R-HSA-5663205 1.000000e+00 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 1.000000e+00 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 1.000000e+00 0.000 0 0
Visual phototransduction R-HSA-2187338 1.000000e+00 0.000 0 0
Disease R-HSA-1643685 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
GPCR downstream signalling R-HSA-388396 1.000000e+00 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.000000e+00 0.000 0 0
Translation R-HSA-72766 1.000000e+00 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
Innate Immune System R-HSA-168249 1.000000e+00 0.000 1 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
G alpha (i) signalling events R-HSA-418594 1.000000e+00 0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 -0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 -0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 -0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Cell Cycle R-HSA-1640170 5.055956e-13 12.296 0 0
Cell Cycle, Mitotic R-HSA-69278 1.022016e-11 10.991 0 0
M Phase R-HSA-68886 4.833419e-09 8.316 0 0
Mitotic Prometaphase R-HSA-68877 6.348702e-09 8.197 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 2.800226e-07 6.553 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.734079e-07 6.563 0 0
Separation of Sister Chromatids R-HSA-2467813 3.822853e-07 6.418 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 7.642321e-07 6.117 0 0
Mitotic Anaphase R-HSA-68882 8.015434e-07 6.096 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 8.922004e-07 6.050 0 0
Signal Transduction R-HSA-162582 2.124259e-06 5.673 1 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 3.645908e-06 5.438 0 0
Chromatin organization R-HSA-4839726 4.041434e-06 5.393 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 4.461713e-06 5.350 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 5.917433e-06 5.228 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 6.421088e-06 5.192 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 8.247219e-06 5.084 0 0
Nuclear import of Rev protein R-HSA-180746 7.779945e-06 5.109 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 8.247219e-06 5.084 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 9.095933e-06 5.041 0 0
Cell Cycle Checkpoints R-HSA-69620 9.077202e-06 5.042 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.208924e-05 4.918 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.208924e-05 4.918 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.528998e-05 4.816 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.684788e-05 4.773 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.680189e-05 4.775 0 0
Cellular response to heat stress R-HSA-3371556 1.800481e-05 4.745 0 0
mTORC1-mediated signalling R-HSA-166208 2.048548e-05 4.689 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 2.076747e-05 4.683 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.147556e-05 4.668 0 0
Chromatin modifying enzymes R-HSA-3247509 2.371143e-05 4.625 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.487515e-05 4.604 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.764513e-05 4.558 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 2.686765e-05 4.571 0 0
Nuclear Envelope Breakdown R-HSA-2980766 2.663963e-05 4.574 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.764513e-05 4.558 0 0
Amplification of signal from the kinetochores R-HSA-141424 3.202034e-05 4.495 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 3.202034e-05 4.495 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.419028e-05 4.466 0 0
snRNP Assembly R-HSA-191859 3.856933e-05 4.414 0 0
Metabolism of non-coding RNA R-HSA-194441 3.856933e-05 4.414 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 3.746088e-05 4.426 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.347355e-05 4.362 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 4.390845e-05 4.357 0 0
Recycling pathway of L1 R-HSA-437239 4.892136e-05 4.311 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.071354e-05 4.150 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 7.989246e-05 4.097 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.076615e-04 3.968 0 0
Aggrephagy R-HSA-9646399 1.325854e-04 3.878 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.369168e-04 3.864 0 0
Apoptotic execution phase R-HSA-75153 1.445297e-04 3.840 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.522228e-04 3.818 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.496391e-04 3.825 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 1.623271e-04 3.790 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.626870e-04 3.789 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.695285e-04 3.771 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.767372e-04 3.753 0 0
Activation of BH3-only proteins R-HSA-114452 1.847192e-04 3.733 0 0
Gene expression (Transcription) R-HSA-74160 1.945908e-04 3.711 0 0
tRNA processing in the nucleus R-HSA-6784531 2.072250e-04 3.684 0 0
MTOR signalling R-HSA-165159 2.393190e-04 3.621 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.419436e-04 3.616 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.419436e-04 3.616 0 0
Gap junction trafficking and regulation R-HSA-157858 2.485676e-04 3.605 0 0
Formation of annular gap junctions R-HSA-196025 2.854707e-04 3.544 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 3.245643e-04 3.489 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 3.525462e-04 3.453 0 0
Gap junction trafficking R-HSA-190828 3.456128e-04 3.461 0 0
Apoptosis R-HSA-109581 3.580217e-04 3.446 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.747510e-04 3.426 0 0
AURKA Activation by TPX2 R-HSA-8854518 3.779948e-04 3.423 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 4.123328e-04 3.385 0 0
Gap junction degradation R-HSA-190873 4.502698e-04 3.347 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 4.459438e-04 3.351 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 4.781762e-04 3.320 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 4.874326e-04 3.312 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.896807e-04 3.310 0 0
Viral Messenger RNA Synthesis R-HSA-168325 5.369294e-04 3.270 0 0
Transport of connexons to the plasma membrane R-HSA-190872 5.943114e-04 3.226 0 0
MITF-M-dependent gene expression R-HSA-9856651 5.811575e-04 3.236 0 0
Mitotic Prophase R-HSA-68875 6.092896e-04 3.215 0 0
G2/M Transition R-HSA-69275 6.449059e-04 3.191 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 6.601566e-04 3.180 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 6.798113e-04 3.168 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 6.811956e-04 3.167 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 8.422516e-04 3.075 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 8.830870e-04 3.054 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 9.946112e-04 3.002 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 9.707998e-04 3.013 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 9.855906e-04 3.006 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 9.855906e-04 3.006 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 9.279055e-04 3.032 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 9.279055e-04 3.032 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 1.010173e-03 2.996 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.018373e-03 2.992 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.100620e-03 2.958 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.221509e-03 2.913 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.337323e-03 2.874 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.337323e-03 2.874 0 0
Centrosome maturation R-HSA-380287 1.242625e-03 2.906 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.319090e-03 2.880 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 1.291383e-03 2.889 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.341581e-03 2.872 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.390849e-03 2.857 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 1.446427e-03 2.840 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.507392e-03 2.822 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.769113e-03 2.752 0 0
Nuclear Receptor transcription pathway R-HSA-383280 1.769113e-03 2.752 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 1.942206e-03 2.712 0 0
Repression of WNT target genes R-HSA-4641265 1.942206e-03 2.712 0 0
Cell junction organization R-HSA-446728 2.017529e-03 2.695 0 0
L1CAM interactions R-HSA-373760 2.106544e-03 2.676 0 0
HIV Life Cycle R-HSA-162587 2.128949e-03 2.672 0 0
NRAGE signals death through JNK R-HSA-193648 2.195095e-03 2.659 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.524949e-03 2.598 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.539893e-03 2.595 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 2.684026e-03 2.571 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 2.926416e-03 2.534 0 0
Clathrin-mediated endocytosis R-HSA-8856828 2.955223e-03 2.529 0 0
Neurodegenerative Diseases R-HSA-8863678 3.091389e-03 2.510 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.091389e-03 2.510 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 3.144915e-03 2.502 0 0
Oncogenic MAPK signaling R-HSA-6802957 3.752364e-03 2.426 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 4.039127e-03 2.394 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 4.070389e-03 2.390 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 4.237814e-03 2.373 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.491455e-03 2.348 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 4.506839e-03 2.346 0 0
Myogenesis R-HSA-525793 4.524329e-03 2.344 0 0
HCMV Early Events R-HSA-9609690 4.741352e-03 2.324 0 0
Programmed Cell Death R-HSA-5357801 4.831436e-03 2.316 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.019186e-03 2.299 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 5.268125e-03 2.278 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.430125e-03 2.265 0 0
G2/M Checkpoints R-HSA-69481 5.649064e-03 2.248 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 5.891432e-03 2.230 0 0
Selective autophagy R-HSA-9663891 5.535460e-03 2.257 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 5.577498e-03 2.254 0 0
PKR-mediated signaling R-HSA-9833482 5.323248e-03 2.274 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 6.083217e-03 2.216 0 0
Metabolism of RNA R-HSA-8953854 6.191822e-03 2.208 0 0
Membrane Trafficking R-HSA-199991 6.209461e-03 2.207 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 6.534278e-03 2.185 0 0
G2/M DNA damage checkpoint R-HSA-69473 6.843572e-03 2.165 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 6.867164e-03 2.163 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 6.867164e-03 2.163 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 7.172667e-03 2.144 0 0
MET interacts with TNS proteins R-HSA-8875513 7.678197e-03 2.115 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 8.719244e-03 2.060 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 8.862565e-03 2.052 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 7.999845e-03 2.097 0 0
S Phase R-HSA-69242 8.202261e-03 2.086 0 0
Host Interactions of HIV factors R-HSA-162909 8.348597e-03 2.078 0 0
Signaling by Hippo R-HSA-2028269 8.858848e-03 2.053 0 0
Cell-Cell communication R-HSA-1500931 8.360504e-03 2.078 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 9.177999e-03 2.037 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 9.225647e-03 2.035 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 9.457139e-03 2.024 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 9.553389e-03 2.020 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.005300e-02 1.998 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 1.031679e-02 1.986 0 0
Cilium Assembly R-HSA-5617833 1.056193e-02 1.976 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.126613e-02 1.948 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.126613e-02 1.948 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.126613e-02 1.948 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.126613e-02 1.948 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.126613e-02 1.948 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.126613e-02 1.948 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.214069e-02 1.916 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 1.214069e-02 1.916 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 1.214069e-02 1.916 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.136647e-02 1.944 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 1.136647e-02 1.944 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.181582e-02 1.928 0 0
Post NMDA receptor activation events R-HSA-438064 1.114724e-02 1.953 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.188297e-02 1.925 1 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.200732e-02 1.921 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 1.200732e-02 1.921 0 0
Inositol phosphate metabolism R-HSA-1483249 1.170560e-02 1.932 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.224778e-02 1.912 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.224778e-02 1.912 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.224778e-02 1.912 0 0
Signaling by RAS mutants R-HSA-6802949 1.224778e-02 1.912 0 0
TGFBR3 expression R-HSA-9839394 1.282213e-02 1.892 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.308248e-02 1.883 0 0
Rap1 signalling R-HSA-392517 1.311030e-02 1.882 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.374509e-02 1.862 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.466931e-02 1.834 0 0
Signaling by EGFR R-HSA-177929 1.469273e-02 1.833 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.498925e-02 1.824 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 1.498925e-02 1.824 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.515804e-02 1.819 0 0
NGF-stimulated transcription R-HSA-9031628 1.536621e-02 1.813 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.599848e-02 1.796 0 0
ALK mutants bind TKIs R-HSA-9700645 1.599848e-02 1.796 0 0
MAP2K and MAPK activation R-HSA-5674135 1.774917e-02 1.751 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 1.713032e-02 1.766 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.569706e-02 1.804 0 0
HIV Infection R-HSA-162906 1.591745e-02 1.798 0 0
Gap junction assembly R-HSA-190861 1.793746e-02 1.746 0 0
Unwinding of DNA R-HSA-176974 1.599848e-02 1.796 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.561031e-02 1.807 0 0
Interferon Signaling R-HSA-913531 1.581497e-02 1.801 0 0
Glycolysis R-HSA-70171 1.773835e-02 1.751 0 0
Cellular Senescence R-HSA-2559583 1.822525e-02 1.739 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 1.877056e-02 1.727 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.877056e-02 1.727 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.877056e-02 1.727 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 1.989734e-02 1.701 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 2.008286e-02 1.697 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 2.073427e-02 1.683 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.146167e-02 1.668 0 0
Death Receptor Signaling R-HSA-73887 2.146167e-02 1.668 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.226664e-02 1.652 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.261594e-02 1.646 1 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 2.263952e-02 1.645 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 2.263952e-02 1.645 0 0
Breakdown of the nuclear lamina R-HSA-352238 2.406941e-02 1.619 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.474616e-02 1.606 0 0
Generic Transcription Pathway R-HSA-212436 2.545781e-02 1.594 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.552451e-02 1.593 0 0
RNA Polymerase II Transcription R-HSA-73857 2.563627e-02 1.591 0 0
Activation of the pre-replicative complex R-HSA-68962 2.627388e-02 1.580 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 2.645658e-02 1.577 0 0
Signaling by NTRKs R-HSA-166520 2.677911e-02 1.572 1 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.713446e-02 1.566 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 2.713446e-02 1.566 0 0
Adherens junctions interactions R-HSA-418990 2.745573e-02 1.561 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 2.980974e-02 1.526 0 0
G0 and Early G1 R-HSA-1538133 3.365272e-02 1.473 0 0
DNA strand elongation R-HSA-69190 3.365272e-02 1.473 0 0
FOXO-mediated transcription R-HSA-9614085 3.212119e-02 1.493 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 3.255796e-02 1.487 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 3.227936e-02 1.491 0 0
Signaling by NOTCH3 R-HSA-9012852 3.098045e-02 1.509 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.074735e-02 1.512 0 0
DNA Repair R-HSA-73894 3.154239e-02 1.501 0 0
Signaling by ALK in cancer R-HSA-9700206 3.074735e-02 1.512 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 2.823996e-02 1.549 0 0
Macroautophagy R-HSA-1632852 2.992224e-02 1.524 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 3.395532e-02 1.469 0 0
Deubiquitination R-HSA-5688426 3.466325e-02 1.460 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.495705e-02 1.456 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 3.557814e-02 1.449 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.654519e-02 1.437 0 0
Regulation of CDH1 Function R-HSA-9764561 3.698053e-02 1.432 0 0
mRNA Splicing R-HSA-72172 3.730801e-02 1.428 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 3.772993e-02 1.423 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 3.772993e-02 1.423 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.781169e-02 1.422 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 3.781169e-02 1.422 0 0
UCH proteinases R-HSA-5689603 3.851496e-02 1.414 0 0
HDMs demethylate histones R-HSA-3214842 3.877244e-02 1.411 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.900133e-02 1.409 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.900133e-02 1.409 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 3.968161e-02 1.401 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.974118e-02 1.401 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 3.974118e-02 1.401 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 3.974118e-02 1.401 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.974118e-02 1.401 0 0
mRNA Editing: A to I Conversion R-HSA-75064 4.064485e-02 1.391 0 0
Regulation of TP53 Expression R-HSA-6804754 4.064485e-02 1.391 0 0
C6 deamination of adenosine R-HSA-75102 4.064485e-02 1.391 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.064485e-02 1.391 0 0
Autophagy R-HSA-9612973 4.068068e-02 1.391 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 4.275922e-02 1.369 0 0
HCMV Infection R-HSA-9609646 4.335770e-02 1.363 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 4.374057e-02 1.359 0 0
Signaling by RAF1 mutants R-HSA-9656223 4.387025e-02 1.358 0 0
Chaperonin-mediated protein folding R-HSA-390466 4.573582e-02 1.340 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 4.610626e-02 1.336 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 4.610626e-02 1.336 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 4.610626e-02 1.336 0 0
MET activates PTPN11 R-HSA-8865999 6.034534e-02 1.219 0 0
Type I hemidesmosome assembly R-HSA-446107 5.799039e-02 1.237 0 0
G1/S-Specific Transcription R-HSA-69205 5.774569e-02 1.238 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 5.697636e-02 1.244 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.137368e-02 1.212 0 0
Formation of definitive endoderm R-HSA-9823730 5.054184e-02 1.296 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 5.637638e-02 1.249 0 0
Semaphorin interactions R-HSA-373755 5.966844e-02 1.224 0 0
HATs acetylate histones R-HSA-3214847 5.921043e-02 1.228 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 6.034534e-02 1.219 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 5.338496e-02 1.273 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 5.728712e-02 1.242 0 0
Nervous system development R-HSA-9675108 5.915868e-02 1.228 0 0
RUNX2 regulates bone development R-HSA-8941326 5.774569e-02 1.238 0 0
Gene Silencing by RNA R-HSA-211000 5.581247e-02 1.253 0 0
Glucose metabolism R-HSA-70326 6.178041e-02 1.209 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 6.308463e-02 1.200 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 6.315746e-02 1.200 0 0
Signaling by NOTCH4 R-HSA-9013694 6.564673e-02 1.183 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 6.593322e-02 1.181 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 6.593322e-02 1.181 0 0
DCC mediated attractive signaling R-HSA-418885 6.593322e-02 1.181 0 0
Estrogen-dependent gene expression R-HSA-9018519 6.613346e-02 1.180 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.639386e-02 1.178 0 0
Protein folding R-HSA-391251 6.659374e-02 1.177 0 0
HDACs deacetylate histones R-HSA-3214815 6.669075e-02 1.176 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 6.669075e-02 1.176 0 0
Cell-cell junction organization R-HSA-421270 6.708562e-02 1.173 0 0
MET promotes cell motility R-HSA-8875878 6.975522e-02 1.156 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 7.010804e-02 1.154 0 0
SARS-CoV Infections R-HSA-9679506 7.045851e-02 1.152 0 0
ER to Golgi Anterograde Transport R-HSA-199977 7.097218e-02 1.149 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 7.116309e-02 1.148 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 7.116309e-02 1.148 0 0
Axon guidance R-HSA-422475 7.293583e-02 1.137 0 0
Signaling by NOTCH1 R-HSA-1980143 7.475905e-02 1.126 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 7.606924e-02 1.119 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 7.606924e-02 1.119 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 7.606924e-02 1.119 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 7.627519e-02 1.118 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 7.627519e-02 1.118 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 7.627800e-02 1.118 0 0
EGFR downregulation R-HSA-182971 7.653616e-02 1.116 0 0
DNA Double Strand Break Response R-HSA-5693606 7.895781e-02 1.103 0 0
Adipogenesis R-HSA-9843745 8.148569e-02 1.089 0 0
Regulation of gap junction activity R-HSA-191650 8.260030e-02 1.083 0 0
NADE modulates death signalling R-HSA-205025 8.260030e-02 1.083 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 8.260030e-02 1.083 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 8.260030e-02 1.083 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 8.260030e-02 1.083 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 8.291318e-02 1.081 0 0
G alpha (12/13) signalling events R-HSA-416482 8.463418e-02 1.072 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 8.554421e-02 1.068 0 0
Signaling by Leptin R-HSA-2586552 8.554421e-02 1.068 0 0
Nucleotide Excision Repair R-HSA-5696398 8.674867e-02 1.062 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 8.737871e-02 1.059 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 8.737871e-02 1.059 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 8.737871e-02 1.059 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 1.069077e-01 0.971 0 0
IRS activation R-HSA-74713 1.069077e-01 0.971 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 1.069077e-01 0.971 0 0
G2 Phase R-HSA-68911 1.069077e-01 0.971 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 1.175677e-01 0.930 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 1.175677e-01 0.930 0 0
Deadenylation of mRNA R-HSA-429947 9.238424e-02 1.034 0 0
HSF1-dependent transactivation R-HSA-3371571 1.006651e-01 0.997 0 0
Orc1 removal from chromatin R-HSA-68949 1.079162e-01 0.967 0 0
mRNA 3'-end processing R-HSA-72187 1.079162e-01 0.967 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.154462e-01 0.938 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 8.989431e-02 1.046 0 0
Signaling by MET R-HSA-6806834 9.527670e-02 1.021 0 0
Synthesis of DNA R-HSA-69239 9.589259e-02 1.018 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 1.175677e-01 0.930 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.117506e-01 0.952 0 0
G1/S Transition R-HSA-69206 9.578628e-02 1.019 0 0
NF-kB is activated and signals survival R-HSA-209560 1.175677e-01 0.930 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 8.907014e-02 1.050 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.023847e-01 0.990 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 9.238424e-02 1.034 0 0
Signaling by NOTCH R-HSA-157118 9.735558e-02 1.012 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 1.175677e-01 0.930 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.011616e-01 0.995 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 9.528237e-02 1.021 0 0
Cellular responses to stress R-HSA-2262752 1.005105e-01 0.998 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 1.008856e-01 0.996 0 0
Developmental Biology R-HSA-1266738 8.959800e-02 1.048 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.117506e-01 0.952 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 9.376508e-02 1.028 1 1
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 9.568673e-02 1.019 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 1.128986e-01 0.947 0 0
NrCAM interactions R-HSA-447038 1.069077e-01 0.971 0 0
Uptake and function of anthrax toxins R-HSA-5210891 9.921496e-02 1.003 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 9.068374e-02 1.042 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.117506e-01 0.952 0 0
SARS-CoV-1-host interactions R-HSA-9692914 9.124898e-02 1.040 0 0
Oncogene Induced Senescence R-HSA-2559585 1.196223e-01 0.922 0 0
PTEN Regulation R-HSA-6807070 1.198417e-01 0.921 0 0
Regulation of TP53 Activity R-HSA-5633007 1.207540e-01 0.918 0 0
Cyclin D associated events in G1 R-HSA-69231 1.225533e-01 0.912 0 0
G1 Phase R-HSA-69236 1.225533e-01 0.912 0 0
E2F mediated regulation of DNA replication R-HSA-113510 1.249483e-01 0.903 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 1.249483e-01 0.903 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 1.294369e-01 0.888 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 1.307145e-01 0.884 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 1.328272e-01 0.877 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 1.328272e-01 0.877 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 1.328272e-01 0.877 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.335518e-01 0.874 0 0
Circadian clock R-HSA-9909396 1.342853e-01 0.872 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.350146e-01 0.870 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.350146e-01 0.870 0 0
VLDLR internalisation and degradation R-HSA-8866427 1.350146e-01 0.870 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.350146e-01 0.870 0 0
HIV elongation arrest and recovery R-HSA-167287 1.353926e-01 0.868 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.353926e-01 0.868 0 0
Negative regulation of MET activity R-HSA-6807004 1.387677e-01 0.858 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.396247e-01 0.855 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.396641e-01 0.855 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.396641e-01 0.855 0 0
Signaling by TGFBR3 R-HSA-9839373 1.405800e-01 0.852 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 1.463562e-01 0.835 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.463562e-01 0.835 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 1.476857e-01 0.831 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.500474e-01 0.824 0 0
Signaling by VEGF R-HSA-194138 1.506078e-01 0.822 1 0
Diseases of programmed cell death R-HSA-9645723 1.525063e-01 0.817 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 1.531659e-01 0.815 0 0
Early Phase of HIV Life Cycle R-HSA-162594 1.531659e-01 0.815 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 1.531659e-01 0.815 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 1.532836e-01 0.815 0 0
Formation of axial mesoderm R-HSA-9796292 1.532836e-01 0.815 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 1.532836e-01 0.815 0 0
Frs2-mediated activation R-HSA-170968 1.532836e-01 0.815 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.535983e-01 0.814 0 0
Vesicle-mediated transport R-HSA-5653656 1.577673e-01 0.802 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.598261e-01 0.796 0 0
Signaling by ALK R-HSA-201556 1.610641e-01 0.793 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 2.112999e-01 0.675 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 2.112999e-01 0.675 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.112999e-01 0.675 0 0
Defective VWF binding to collagen type I R-HSA-9845622 2.112999e-01 0.675 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.112999e-01 0.675 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.112999e-01 0.675 0 0
Defective MMADHC causes MMAHCD R-HSA-3359473 2.112999e-01 0.675 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 1.880094e-01 0.726 0 0
IFNG signaling activates MAPKs R-HSA-9732724 1.880094e-01 0.726 0 0
SOS-mediated signalling R-HSA-112412 1.880094e-01 0.726 0 0
Recycling of eIF2:GDP R-HSA-72731 1.880094e-01 0.726 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 1.880094e-01 0.726 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 2.166438e-01 0.664 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 2.166438e-01 0.664 0 0
MET receptor recycling R-HSA-8875656 2.166438e-01 0.664 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 2.166438e-01 0.664 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.722730e-01 0.764 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 2.456233e-01 0.610 0 0
Regulated proteolysis of p75NTR R-HSA-193692 2.456233e-01 0.610 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.918827e-01 0.717 0 0
Processive synthesis on the lagging strand R-HSA-69183 1.918827e-01 0.717 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.918827e-01 0.717 0 0
Phosphorylation of the APC/C R-HSA-176412 2.120144e-01 0.674 0 0
Notch-HLH transcription pathway R-HSA-350054 1.835173e-01 0.736 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.156294e-01 0.666 0 0
Attenuation phase R-HSA-3371568 1.722848e-01 0.764 0 0
Striated Muscle Contraction R-HSA-390522 2.129327e-01 0.672 0 0
RAF activation R-HSA-5673000 2.270459e-01 0.644 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.015049e-01 0.696 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.125361e-01 0.673 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.455189e-01 0.610 0 0
Nucleosome assembly R-HSA-774815 2.455189e-01 0.610 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.352322e-01 0.629 0 0
Signaling by NOTCH2 R-HSA-1980145 2.270459e-01 0.644 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.250223e-01 0.648 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.250223e-01 0.648 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.250223e-01 0.648 0 0
p75NTR signals via NF-kB R-HSA-193639 1.918827e-01 0.717 0 0
p75NTR regulates axonogenesis R-HSA-193697 2.456233e-01 0.610 0 0
Chromosome Maintenance R-HSA-73886 1.891806e-01 0.723 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 2.166438e-01 0.664 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 2.325734e-01 0.633 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 2.322656e-01 0.634 0 0
Regulation of mitotic cell cycle R-HSA-453276 1.791561e-01 0.747 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 1.791561e-01 0.747 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.125361e-01 0.673 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.985539e-01 0.702 0 0
mRNA Editing R-HSA-75072 2.456233e-01 0.610 0 0
Calcineurin activates NFAT R-HSA-2025928 2.456233e-01 0.610 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 2.325734e-01 0.633 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 2.198847e-01 0.658 0 0
RNA Polymerase I Transcription R-HSA-73864 2.453238e-01 0.610 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.120144e-01 0.674 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 2.255880e-01 0.647 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.956440e-01 0.709 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.956440e-01 0.709 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.755235e-01 0.756 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.755235e-01 0.756 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.755235e-01 0.756 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.755235e-01 0.756 0 0
FGFR1 mutant receptor activation R-HSA-1839124 1.991128e-01 0.701 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 2.456233e-01 0.610 0 0
Prolonged ERK activation events R-HSA-169893 2.120144e-01 0.674 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.880782e-01 0.726 0 0
ARL13B-mediated ciliary trafficking of INPP5E R-HSA-5624958 2.112999e-01 0.675 0 0
Transport of connexins along the secretory pathway R-HSA-190827 2.112999e-01 0.675 0 0
Manipulation of host energy metabolism R-HSA-9636667 2.112999e-01 0.675 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.156294e-01 0.666 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.722848e-01 0.764 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.850754e-01 0.733 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.327035e-01 0.633 0 0
Smooth Muscle Contraction R-HSA-445355 2.125361e-01 0.673 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.851212e-01 0.733 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.165904e-01 0.664 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 1.880094e-01 0.726 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 2.070233e-01 0.684 0 0
Oligomerization of connexins into connexons R-HSA-190704 2.112999e-01 0.675 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.755235e-01 0.756 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 2.166438e-01 0.664 0 0
Potential therapeutics for SARS R-HSA-9679191 1.850585e-01 0.733 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.410228e-01 0.618 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 2.456233e-01 0.610 0 0
LDL clearance R-HSA-8964038 1.835173e-01 0.736 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 1.991128e-01 0.701 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 2.456233e-01 0.610 0 0
Heme signaling R-HSA-9707616 1.948445e-01 0.710 0 0
Miscellaneous transport and binding events R-HSA-5223345 2.129327e-01 0.672 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.680979e-01 0.774 0 0
tRNA processing R-HSA-72306 2.461390e-01 0.609 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.468687e-01 0.608 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 2.491213e-01 0.604 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.534690e-01 0.596 0 0
Gastrulation R-HSA-9758941 2.546229e-01 0.594 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 2.713065e-01 0.567 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 2.713065e-01 0.567 0 0
Regulation of cortical dendrite branching R-HSA-8985801 2.713065e-01 0.567 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 2.713065e-01 0.567 0 0
Enhanced cleavage of VWF variant by ADAMTS13 R-HSA-9845619 2.713065e-01 0.567 0 0
Defective VWF cleavage by ADAMTS13 variant R-HSA-9845621 2.713065e-01 0.567 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 2.713065e-01 0.567 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 2.713065e-01 0.567 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 2.713065e-01 0.567 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 2.713065e-01 0.567 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 2.713065e-01 0.567 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 2.713065e-01 0.567 0 0
Defective MMACHC causes MAHCC R-HSA-3359474 3.267509e-01 0.486 0 0
Axonal growth stimulation R-HSA-209563 3.267509e-01 0.486 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 3.267509e-01 0.486 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 3.267509e-01 0.486 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 3.267509e-01 0.486 0 0
HCN channels R-HSA-1296061 3.779797e-01 0.423 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 3.779797e-01 0.423 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 3.779797e-01 0.423 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 3.779797e-01 0.423 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 3.779797e-01 0.423 0 0
Signaling by MAP2K mutants R-HSA-9652169 3.779797e-01 0.423 0 0
Binding and entry of HIV virion R-HSA-173107 2.747300e-01 0.561 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 2.747300e-01 0.561 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 4.253133e-01 0.371 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 4.253133e-01 0.371 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 3.326048e-01 0.478 0 0
Anchoring fibril formation R-HSA-2214320 3.326048e-01 0.478 0 0
Activation of RAC1 R-HSA-428540 3.326048e-01 0.478 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.326048e-01 0.478 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 2.746147e-01 0.561 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.959289e-01 0.529 0 0
MET activates RAS signaling R-HSA-8851805 3.610790e-01 0.442 0 0
p75NTR recruits signalling complexes R-HSA-209543 3.610790e-01 0.442 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 3.610790e-01 0.442 0 0
Leading Strand Synthesis R-HSA-69109 3.610790e-01 0.442 0 0
Polymerase switching R-HSA-69091 3.610790e-01 0.442 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 4.690476e-01 0.329 0 0
Plus-strand DNA synthesis R-HSA-164525 4.690476e-01 0.329 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 4.690476e-01 0.329 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 4.690476e-01 0.329 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 4.690476e-01 0.329 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 4.690476e-01 0.329 0 0
Signaling by RNF43 mutants R-HSA-5340588 4.690476e-01 0.329 0 0
Interaction between L1 and Ankyrins R-HSA-445095 2.662668e-01 0.575 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 2.662668e-01 0.575 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 2.662668e-01 0.575 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 3.173352e-01 0.498 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 2.836175e-01 0.547 0 0
Formation of the Early Elongation Complex R-HSA-113418 2.836175e-01 0.547 0 0
HSF1 activation R-HSA-3371511 2.560365e-01 0.592 0 0
Lagging Strand Synthesis R-HSA-69186 3.387623e-01 0.470 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 3.011287e-01 0.521 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.601440e-01 0.444 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.601440e-01 0.444 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 3.601440e-01 0.444 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 4.165338e-01 0.380 0 0
Removal of the Flap Intermediate R-HSA-69166 4.165338e-01 0.380 0 0
Signaling by LTK in cancer R-HSA-9842640 5.094560e-01 0.293 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.094560e-01 0.293 0 0
Autointegration results in viral DNA circles R-HSA-177539 5.094560e-01 0.293 0 0
Uncoating of the HIV Virion R-HSA-162585 5.094560e-01 0.293 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 5.094560e-01 0.293 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 5.094560e-01 0.293 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 2.717238e-01 0.566 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.850732e-01 0.545 0 0
FGFR2 alternative splicing R-HSA-6803529 3.814198e-01 0.419 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.162631e-01 0.500 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 2.706461e-01 0.568 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 3.542027e-01 0.451 0 0
Erythropoietin activates RAS R-HSA-9027284 4.433437e-01 0.353 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 4.433437e-01 0.353 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 4.025341e-01 0.395 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 4.025341e-01 0.395 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 3.396503e-01 0.469 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 4.234363e-01 0.373 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 3.534914e-01 0.452 0 0
Translation initiation complex formation R-HSA-72649 3.673730e-01 0.435 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 4.440811e-01 0.353 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 4.948175e-01 0.306 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 3.400325e-01 0.468 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 3.951852e-01 0.403 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 3.951852e-01 0.403 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.242812e-01 0.372 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 3.187573e-01 0.497 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 4.165338e-01 0.380 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.165338e-01 0.380 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 2.747300e-01 0.561 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 3.252215e-01 0.488 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 3.601440e-01 0.444 0 0
PI3K/AKT activation R-HSA-198203 2.747300e-01 0.561 0 0
Polo-like kinase mediated events R-HSA-156711 2.746147e-01 0.561 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 4.844397e-01 0.315 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 4.933038e-01 0.307 0 0
DNA Replication Pre-Initiation R-HSA-69002 2.552588e-01 0.593 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 3.779797e-01 0.423 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 3.610790e-01 0.442 0 0
Trafficking of AMPA receptors R-HSA-399719 3.364619e-01 0.473 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 4.367663e-01 0.360 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 5.018313e-01 0.299 0 0
Integration of provirus R-HSA-162592 3.326048e-01 0.478 0 0
Formation of the posterior neural plate R-HSA-9832991 3.037769e-01 0.517 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 4.165338e-01 0.380 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.656220e-01 0.576 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.395865e-01 0.357 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 4.776187e-01 0.321 0 0
DNA Replication R-HSA-69306 4.851931e-01 0.314 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 3.610790e-01 0.442 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 3.890866e-01 0.410 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.601440e-01 0.444 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 4.644276e-01 0.333 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 3.906530e-01 0.408 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 3.779797e-01 0.423 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 3.779797e-01 0.423 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 4.690476e-01 0.329 0 0
CRMPs in Sema3A signaling R-HSA-399956 4.165338e-01 0.380 0 0
MET Receptor Activation R-HSA-6806942 5.094560e-01 0.293 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 3.896432e-01 0.409 0 0
Neurexins and neuroligins R-HSA-6794361 3.396503e-01 0.469 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 3.326048e-01 0.478 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.908525e-01 0.536 0 0
MAP kinase activation R-HSA-450294 3.073496e-01 0.512 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 4.933038e-01 0.307 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 2.662668e-01 0.575 0 0
EPH-Ephrin signaling R-HSA-2682334 4.172254e-01 0.380 0 0
Interleukin-17 signaling R-HSA-448424 4.212120e-01 0.375 0 0
MAPK family signaling cascades R-HSA-5683057 3.811532e-01 0.419 0 0
Signalling to ERK5 R-HSA-198765 2.713065e-01 0.567 0 0
MET activates STAT3 R-HSA-8875791 3.267509e-01 0.486 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 3.267509e-01 0.486 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 2.747300e-01 0.561 0 0
Bicarbonate transporters R-HSA-425381 3.037769e-01 0.517 0 0
Ionotropic activity of kainate receptors R-HSA-451306 3.037769e-01 0.517 0 0
Reelin signalling pathway R-HSA-8866376 4.253133e-01 0.371 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 4.253133e-01 0.371 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 4.690476e-01 0.329 0 0
Ceramide signalling R-HSA-193681 4.690476e-01 0.329 0 0
Regulation of KIT signaling R-HSA-1433559 4.165338e-01 0.380 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 4.165338e-01 0.380 0 0
Intraflagellar transport R-HSA-5620924 2.850732e-01 0.545 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 4.433437e-01 0.353 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.864889e-01 0.543 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 4.433437e-01 0.353 0 0
Homology Directed Repair R-HSA-5693538 3.543201e-01 0.451 0 0
Signal attenuation R-HSA-74749 2.747300e-01 0.561 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 4.253133e-01 0.371 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 3.173352e-01 0.498 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.708557e-01 0.567 0 0
TBC/RABGAPs R-HSA-8854214 3.779917e-01 0.423 0 0
Long-term potentiation R-HSA-9620244 4.440811e-01 0.353 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 4.778000e-01 0.321 0 0
HCMV Late Events R-HSA-9610379 4.130749e-01 0.384 0 0
Cellular responses to stimuli R-HSA-8953897 2.816065e-01 0.550 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.253133e-01 0.371 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.690476e-01 0.329 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 4.675796e-01 0.330 0 0
ESR-mediated signaling R-HSA-8939211 4.706750e-01 0.327 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.545882e-01 0.342 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 3.892986e-01 0.410 0 0
Signaling by WNT R-HSA-195721 4.598278e-01 0.337 0 0
Mitochondrial biogenesis R-HSA-1592230 3.449981e-01 0.462 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 3.162631e-01 0.500 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 3.162631e-01 0.500 0 0
DNA Damage Bypass R-HSA-73893 2.985604e-01 0.525 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 2.795977e-01 0.553 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.850732e-01 0.545 0 0
Signalling to ERKs R-HSA-187687 4.247992e-01 0.372 1 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 4.941148e-01 0.306 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 4.941148e-01 0.306 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 4.941148e-01 0.306 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 3.779797e-01 0.423 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 2.747300e-01 0.561 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 4.253133e-01 0.371 0 0
The NLRP3 inflammasome R-HSA-844456 2.959289e-01 0.529 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 5.094560e-01 0.293 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.719418e-01 0.430 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.198010e-01 0.495 0 0
Disorders of Developmental Biology R-HSA-9675151 4.948175e-01 0.306 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 4.912888e-01 0.309 0 0
Signaling by PTK6 R-HSA-8848021 4.912888e-01 0.309 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 3.011287e-01 0.521 0 0
MHC class II antigen presentation R-HSA-2132295 2.932688e-01 0.533 0 0
Signaling by FGFR in disease R-HSA-1226099 3.252215e-01 0.488 0 0
Basigin interactions R-HSA-210991 3.387623e-01 0.470 0 0
Histamine receptors R-HSA-390650 3.267509e-01 0.486 0 0
DAG and IP3 signaling R-HSA-1489509 4.088992e-01 0.388 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 3.950720e-01 0.403 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 4.253133e-01 0.371 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 4.690476e-01 0.329 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 3.890866e-01 0.410 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.601440e-01 0.444 0 0
CREB phosphorylation R-HSA-199920 5.094560e-01 0.293 0 0
Plasma lipoprotein clearance R-HSA-8964043 3.009973e-01 0.521 0 0
Fibronectin matrix formation R-HSA-1566977 4.948175e-01 0.306 0 0
RET signaling R-HSA-8853659 4.421920e-01 0.354 0 0
Hedgehog 'off' state R-HSA-5610787 3.837740e-01 0.416 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 4.212120e-01 0.375 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 4.933038e-01 0.307 0 0
Viral Infection Pathways R-HSA-9824446 3.800046e-01 0.420 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.822949e-01 0.317 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.747300e-01 0.561 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.871261e-01 0.542 0 0
Inflammasomes R-HSA-622312 5.040855e-01 0.297 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 3.022158e-01 0.520 0 0
PIP3 activates AKT signaling R-HSA-1257604 3.637986e-01 0.439 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 4.690476e-01 0.329 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 4.690476e-01 0.329 0 0
Formation of the anterior neural plate R-HSA-9823739 4.433437e-01 0.353 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 4.433437e-01 0.353 0 0
Signaling by TGFB family members R-HSA-9006936 3.383242e-01 0.471 0 0
RMTs methylate histone arginines R-HSA-3214858 3.934620e-01 0.405 0 0
Netrin-1 signaling R-HSA-373752 3.934620e-01 0.405 0 0
Influenza Infection R-HSA-168255 3.089733e-01 0.510 0 0
Josephin domain DUBs R-HSA-5689877 2.747300e-01 0.561 0 0
Cytokine Signaling in Immune system R-HSA-1280215 4.116825e-01 0.385 0 0
Sensory processing of sound R-HSA-9659379 3.838207e-01 0.416 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 4.690476e-01 0.329 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 5.094560e-01 0.293 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 2.574605e-01 0.589 0 0
Kinesins R-HSA-983189 2.949967e-01 0.530 0 0
OAS antiviral response R-HSA-8983711 3.610790e-01 0.442 0 0
Regulation of beta-cell development R-HSA-186712 4.367663e-01 0.360 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 3.396503e-01 0.469 0 0
Regulation of TNFR1 signaling R-HSA-5357905 4.242812e-01 0.372 0 0
XBP1(S) activates chaperone genes R-HSA-381038 4.779259e-01 0.321 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.601440e-01 0.444 0 0
Growth hormone receptor signaling R-HSA-982772 4.025341e-01 0.395 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.677710e-01 0.330 0 0
SLC transporter disorders R-HSA-5619102 3.945044e-01 0.404 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 5.099067e-01 0.293 0 0
HIV Transcription Elongation R-HSA-167169 5.099067e-01 0.293 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 5.099067e-01 0.293 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 5.099067e-01 0.293 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 5.193952e-01 0.285 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 5.193952e-01 0.285 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 5.193952e-01 0.285 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 5.193952e-01 0.285 0 0
Specification of primordial germ cells R-HSA-9827857 5.193952e-01 0.285 0 0
PCP/CE pathway R-HSA-4086400 5.210168e-01 0.283 0 0
Signaling by Erythropoietin R-HSA-9006335 5.233372e-01 0.281 0 0
Late endosomal microautophagy R-HSA-9615710 5.233372e-01 0.281 0 0
mRNA Capping R-HSA-72086 5.233372e-01 0.281 0 0
Base Excision Repair R-HSA-73884 5.237830e-01 0.281 0 0
FLT3 Signaling R-HSA-9607240 5.262581e-01 0.279 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 5.350294e-01 0.272 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 5.386105e-01 0.269 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 5.421710e-01 0.266 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 5.421710e-01 0.266 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 5.423405e-01 0.266 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 5.430250e-01 0.265 0 0
GAB1 signalosome R-HSA-180292 5.431602e-01 0.265 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 5.431602e-01 0.265 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 5.431602e-01 0.265 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 5.431602e-01 0.265 0 0
Ephrin signaling R-HSA-3928664 5.431602e-01 0.265 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 5.431602e-01 0.265 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 5.431602e-01 0.265 0 0
Synaptic adhesion-like molecules R-HSA-8849932 5.431602e-01 0.265 0 0
Mismatch Repair R-HSA-5358508 5.431602e-01 0.265 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 5.439633e-01 0.264 0 0
IRE1alpha activates chaperones R-HSA-381070 5.461739e-01 0.263 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 5.463576e-01 0.263 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 5.467914e-01 0.262 0 0
Disinhibition of SNARE formation R-HSA-114516 5.467914e-01 0.262 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 5.467914e-01 0.262 0 0
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake R-HSA-9031525 5.467914e-01 0.262 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 5.467914e-01 0.262 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 5.467914e-01 0.262 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 5.467914e-01 0.262 0 0
PTK6 Expression R-HSA-8849473 5.467914e-01 0.262 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 5.467914e-01 0.262 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 5.467914e-01 0.262 0 0
VLDL clearance R-HSA-8964046 5.467914e-01 0.262 0 0
Regulation of PTEN localization R-HSA-8948747 5.467914e-01 0.262 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 5.467914e-01 0.262 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.509214e-01 0.259 0 0
Transcription of the HIV genome R-HSA-167172 5.567570e-01 0.254 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.581378e-01 0.253 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 5.583868e-01 0.253 0 0
Budding and maturation of HIV virion R-HSA-162588 5.605666e-01 0.251 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 5.605666e-01 0.251 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 5.651042e-01 0.248 0 0
Regulation of signaling by CBL R-HSA-912631 5.660938e-01 0.247 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 5.660938e-01 0.247 0 0
STING mediated induction of host immune responses R-HSA-1834941 5.660938e-01 0.247 0 0
TNF signaling R-HSA-75893 5.709275e-01 0.243 0 0
Reverse Transcription of HIV RNA R-HSA-162589 5.812872e-01 0.236 0 0
Minus-strand DNA synthesis R-HSA-164516 5.812872e-01 0.236 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 5.812872e-01 0.236 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 5.812872e-01 0.236 0 0
Adrenoceptors R-HSA-390696 5.812872e-01 0.236 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 5.812872e-01 0.236 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 5.812872e-01 0.236 0 0
Sodium/Proton exchangers R-HSA-425986 5.812872e-01 0.236 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 5.818281e-01 0.235 0 0
Rab regulation of trafficking R-HSA-9007101 5.873925e-01 0.231 0 0
Signaling by NODAL R-HSA-1181150 5.881851e-01 0.230 0 0
Protein hydroxylation R-HSA-9629569 5.881851e-01 0.230 0 0
Signal transduction by L1 R-HSA-445144 5.881851e-01 0.230 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.914519e-01 0.228 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 5.959791e-01 0.225 0 0
Nuclear RNA decay R-HSA-9930044 5.959791e-01 0.225 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 5.959791e-01 0.225 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 5.959791e-01 0.225 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 5.959791e-01 0.225 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.959791e-01 0.225 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 6.013274e-01 0.221 0 0
Fanconi Anemia Pathway R-HSA-6783310 6.036885e-01 0.219 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 6.061576e-01 0.217 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 6.062399e-01 0.217 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 6.062399e-01 0.217 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 6.081120e-01 0.216 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.094293e-01 0.215 0 0
ERK/MAPK targets R-HSA-198753 6.094293e-01 0.215 0 0
Extension of Telomeres R-HSA-180786 6.110501e-01 0.214 0 0
Effects of PIP2 hydrolysis R-HSA-114508 6.129714e-01 0.213 0 0
MAPK1 (ERK2) activation R-HSA-112411 6.131593e-01 0.212 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 6.131593e-01 0.212 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 6.131593e-01 0.212 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 6.131593e-01 0.212 0 0
ARMS-mediated activation R-HSA-170984 6.131593e-01 0.212 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.131593e-01 0.212 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 6.131593e-01 0.212 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 6.131593e-01 0.212 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 6.131593e-01 0.212 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 6.131593e-01 0.212 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 6.131593e-01 0.212 0 0
Interleukin-1 processing R-HSA-448706 6.131593e-01 0.212 0 0
Lipophagy R-HSA-9613354 6.131593e-01 0.212 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 6.131593e-01 0.212 0 0
Cellular response to mitochondrial stress R-HSA-9840373 6.131593e-01 0.212 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 6.178373e-01 0.209 0 0
Ca2+ pathway R-HSA-4086398 6.180269e-01 0.209 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 6.182227e-01 0.209 0 0
Telomere Maintenance R-HSA-157579 6.208062e-01 0.207 0 0
Signaling by ERBB2 R-HSA-1227986 6.239289e-01 0.205 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.246395e-01 0.204 0 0
Dual Incision in GG-NER R-HSA-5696400 6.294760e-01 0.201 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 6.294760e-01 0.201 0 0
Ribavirin ADME R-HSA-9755088 6.298273e-01 0.201 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 6.310876e-01 0.200 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.324183e-01 0.199 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 6.337008e-01 0.198 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 6.337008e-01 0.198 0 0
Formation of paraxial mesoderm R-HSA-9793380 6.365487e-01 0.196 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 6.411459e-01 0.193 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 6.426070e-01 0.192 0 0
DNA replication initiation R-HSA-68952 6.426070e-01 0.192 0 0
Folding of actin by CCT/TriC R-HSA-390450 6.426070e-01 0.192 0 0
Regulation of the apoptosome activity R-HSA-9627069 6.426070e-01 0.192 0 0
Formation of apoptosome R-HSA-111458 6.426070e-01 0.192 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 6.426070e-01 0.192 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 6.426070e-01 0.192 0 0
Formation of intermediate mesoderm R-HSA-9761174 6.426070e-01 0.192 0 0
2-LTR circle formation R-HSA-164843 6.426070e-01 0.192 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 6.426070e-01 0.192 0 0
Pexophagy R-HSA-9664873 6.426070e-01 0.192 0 0
Receptor Mediated Mitophagy R-HSA-8934903 6.426070e-01 0.192 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 6.426070e-01 0.192 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 6.426070e-01 0.192 0 0
RAF/MAP kinase cascade R-HSA-5673001 6.441377e-01 0.191 0 0
Regulation of Apoptosis R-HSA-169911 6.454874e-01 0.190 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 6.454874e-01 0.190 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 6.454874e-01 0.190 0 0
Developmental Cell Lineages R-HSA-9734767 6.456826e-01 0.190 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.493849e-01 0.187 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 6.493849e-01 0.187 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 6.493849e-01 0.187 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 6.554448e-01 0.183 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 6.554448e-01 0.183 0 0
Ub-specific processing proteases R-HSA-5689880 6.559575e-01 0.183 0 0
Degradation of CDH1 R-HSA-9766229 6.597704e-01 0.181 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 6.610022e-01 0.180 0 0
RNA Polymerase III Transcription R-HSA-74158 6.610022e-01 0.180 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 6.610022e-01 0.180 0 0
Regulation of TP53 Degradation R-HSA-6804757 6.610022e-01 0.180 0 0
Calmodulin induced events R-HSA-111933 6.610022e-01 0.180 0 0
FLT3 signaling in disease R-HSA-9682385 6.610022e-01 0.180 0 0
CaM pathway R-HSA-111997 6.610022e-01 0.180 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 6.633183e-01 0.178 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 6.681119e-01 0.175 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.681119e-01 0.175 0 0
Organic anion transport by SLCO transporters R-HSA-879518 6.681119e-01 0.175 0 0
Syndecan interactions R-HSA-3000170 6.681119e-01 0.175 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 6.698148e-01 0.174 0 0
vRNA Synthesis R-HSA-192814 6.698148e-01 0.174 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 6.698148e-01 0.174 0 0
PECAM1 interactions R-HSA-210990 6.698148e-01 0.174 0 0
Azathioprine ADME R-HSA-9748787 6.729184e-01 0.172 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 6.760189e-01 0.170 0 0
Collagen chain trimerization R-HSA-8948216 6.760189e-01 0.170 0 0
Signaling by Hedgehog R-HSA-5358351 6.808156e-01 0.167 0 0
Cellular response to hypoxia R-HSA-1234174 6.843433e-01 0.165 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 6.845295e-01 0.165 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 6.845981e-01 0.165 0 0
Platelet degranulation R-HSA-114608 6.854072e-01 0.164 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 6.905383e-01 0.161 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 6.905383e-01 0.161 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 6.920567e-01 0.160 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 6.949527e-01 0.158 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 6.949527e-01 0.158 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 6.949527e-01 0.158 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 6.949527e-01 0.158 0 0
Plasmalogen biosynthesis R-HSA-75896 6.949527e-01 0.158 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 6.981460e-01 0.156 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 6.981460e-01 0.156 0 0
Cap-dependent Translation Initiation R-HSA-72737 6.993273e-01 0.155 0 0
Eukaryotic Translation Initiation R-HSA-72613 6.993273e-01 0.155 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 7.031289e-01 0.153 0 0
Laminin interactions R-HSA-3000157 7.031289e-01 0.153 0 0
Interleukin-7 signaling R-HSA-1266695 7.031289e-01 0.153 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 7.041315e-01 0.152 0 0
Stabilization of p53 R-HSA-69541 7.045625e-01 0.152 0 0
Processing of DNA double-strand break ends R-HSA-5693607 7.052488e-01 0.152 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.061882e-01 0.151 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 7.151379e-01 0.146 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 7.158529e-01 0.145 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 7.180953e-01 0.144 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 7.180953e-01 0.144 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 7.180953e-01 0.144 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 7.180953e-01 0.144 0 0
Scavenging by Class F Receptors R-HSA-3000484 7.181782e-01 0.144 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 7.181782e-01 0.144 0 0
Regulation of IFNG signaling R-HSA-877312 7.181782e-01 0.144 0 0
Signaling by LTK R-HSA-9842663 7.181782e-01 0.144 0 0
Pervasive developmental disorders R-HSA-9005895 7.181782e-01 0.144 0 0
Disorders of Nervous System Development R-HSA-9697154 7.181782e-01 0.144 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 7.181782e-01 0.144 0 0
MET activates PTK2 signaling R-HSA-8874081 7.194532e-01 0.143 0 0
Metalloprotease DUBs R-HSA-5689901 7.194532e-01 0.143 0 0
Urea cycle R-HSA-70635 7.194532e-01 0.143 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.194532e-01 0.143 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 7.311417e-01 0.136 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 7.311417e-01 0.136 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.350141e-01 0.134 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 7.350141e-01 0.134 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 7.378488e-01 0.132 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 7.396367e-01 0.131 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 7.396367e-01 0.131 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 7.396367e-01 0.131 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 7.396367e-01 0.131 0 0
CD28 dependent Vav1 pathway R-HSA-389359 7.396367e-01 0.131 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 7.396367e-01 0.131 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 7.437080e-01 0.129 0 0
HIV Transcription Initiation R-HSA-167161 7.437080e-01 0.129 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 7.437080e-01 0.129 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 7.437080e-01 0.129 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 7.437080e-01 0.129 0 0
Degradation of CRY and PER proteins R-HSA-9932298 7.437080e-01 0.129 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 7.437080e-01 0.129 0 0
Co-inhibition by PD-1 R-HSA-389948 7.462180e-01 0.127 0 0
Hedgehog 'on' state R-HSA-5632684 7.477108e-01 0.126 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.478011e-01 0.126 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.478011e-01 0.126 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 7.498333e-01 0.125 0 0
Pyrimidine salvage R-HSA-73614 7.498333e-01 0.125 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.523831e-01 0.124 0 0
Ca-dependent events R-HSA-111996 7.558016e-01 0.122 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 7.572951e-01 0.121 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 7.594624e-01 0.119 0 0
cGMP effects R-HSA-418457 7.594624e-01 0.119 0 0
Signaling by FGFR4 in disease R-HSA-5655291 7.594624e-01 0.119 0 0
Prolactin receptor signaling R-HSA-1170546 7.594624e-01 0.119 0 0
HDL assembly R-HSA-8963896 7.594624e-01 0.119 0 0
Zinc transporters R-HSA-435354 7.594624e-01 0.119 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 7.594624e-01 0.119 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 7.609314e-01 0.119 0 0
Signaling by ROBO receptors R-HSA-376176 7.637420e-01 0.117 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.639333e-01 0.117 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.639333e-01 0.117 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 7.639333e-01 0.117 0 0
Platelet calcium homeostasis R-HSA-418360 7.639333e-01 0.117 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 7.639333e-01 0.117 0 0
Dual incision in TC-NER R-HSA-6782135 7.653030e-01 0.116 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 7.653030e-01 0.116 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 7.674305e-01 0.115 0 0
Signaling by SCF-KIT R-HSA-1433557 7.674305e-01 0.115 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 7.674305e-01 0.115 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.773379e-01 0.109 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 7.773379e-01 0.109 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 7.773379e-01 0.109 0 0
Interleukin-37 signaling R-HSA-9008059 7.773379e-01 0.109 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 7.777796e-01 0.109 0 0
Telomere C-strand synthesis initiation R-HSA-174430 7.777796e-01 0.109 0 0
p38MAPK events R-HSA-171007 7.777796e-01 0.109 1 1
Protein methylation R-HSA-8876725 7.777796e-01 0.109 0 0
Amine ligand-binding receptors R-HSA-375280 7.786040e-01 0.109 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.830336e-01 0.106 0 0
Unfolded Protein Response (UPR) R-HSA-381119 7.875146e-01 0.104 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 7.893316e-01 0.103 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 7.893316e-01 0.103 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 7.893316e-01 0.103 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 7.893316e-01 0.103 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 7.893316e-01 0.103 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 7.900711e-01 0.102 0 0
Cargo concentration in the ER R-HSA-5694530 7.900711e-01 0.102 0 0
Downstream signal transduction R-HSA-186763 7.900711e-01 0.102 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.942184e-01 0.100 0 0
PLC beta mediated events R-HSA-112043 7.942184e-01 0.100 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 7.947029e-01 0.100 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 7.947029e-01 0.100 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 7.947029e-01 0.100 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 7.947029e-01 0.100 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 7.947029e-01 0.100 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 7.947029e-01 0.100 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 7.947029e-01 0.100 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 7.947029e-01 0.100 0 0
Differentiation of T cells R-HSA-9945266 7.947029e-01 0.100 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 7.947029e-01 0.100 0 0
Negative regulation of FLT3 R-HSA-9706369 7.947029e-01 0.100 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 7.947029e-01 0.100 0 0
Activation of SMO R-HSA-5635838 7.947029e-01 0.100 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 7.996237e-01 0.097 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 7.996237e-01 0.097 0 0
Regulation of pyruvate metabolism R-HSA-9861718 7.996237e-01 0.097 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 7.996237e-01 0.097 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 7.996237e-01 0.097 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.021574e-01 0.096 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 8.021574e-01 0.096 0 0
Signaling by WNT in cancer R-HSA-4791275 8.021574e-01 0.096 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 8.031964e-01 0.095 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.098903e-01 0.092 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.098903e-01 0.092 0 0
RSV-host interactions R-HSA-9833110 8.098903e-01 0.092 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 8.103384e-01 0.091 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 8.103384e-01 0.091 0 0
Coenzyme A biosynthesis R-HSA-196783 8.103384e-01 0.091 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 8.103384e-01 0.091 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 8.103384e-01 0.091 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 8.103384e-01 0.091 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 8.118538e-01 0.091 0 0
Integrin signaling R-HSA-354192 8.136215e-01 0.090 0 0
G-protein beta:gamma signalling R-HSA-397795 8.136215e-01 0.090 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 8.136215e-01 0.090 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 8.159442e-01 0.088 0 0
Muscle contraction R-HSA-397014 8.161508e-01 0.088 0 0
Co-stimulation by CD28 R-HSA-389356 8.189445e-01 0.087 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 8.201972e-01 0.086 1 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 8.244879e-01 0.084 0 0
Resolution of D-Loop Structures R-HSA-5693537 8.244879e-01 0.084 0 0
Vpu mediated degradation of CD4 R-HSA-180534 8.244879e-01 0.084 0 0
Glutamate and glutamine metabolism R-HSA-8964539 8.244879e-01 0.084 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 8.245709e-01 0.084 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 8.247839e-01 0.084 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 8.247839e-01 0.084 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 8.247839e-01 0.084 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 8.247839e-01 0.084 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 8.247839e-01 0.084 0 0
Glycogen storage diseases R-HSA-3229121 8.247839e-01 0.084 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 8.247839e-01 0.084 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 8.247839e-01 0.084 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 8.247839e-01 0.084 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.247839e-01 0.084 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 8.279957e-01 0.082 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 8.279957e-01 0.082 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 8.279957e-01 0.082 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 8.282330e-01 0.082 0 0
Collagen formation R-HSA-1474290 8.296482e-01 0.081 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 8.347812e-01 0.078 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 8.347812e-01 0.078 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 8.347812e-01 0.078 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 8.347812e-01 0.078 0 0
Mitophagy R-HSA-5205647 8.347812e-01 0.078 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 8.347812e-01 0.078 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 8.347812e-01 0.078 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 8.347812e-01 0.078 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 8.347812e-01 0.078 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 8.355826e-01 0.078 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 8.355826e-01 0.078 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 8.361879e-01 0.078 0 0
Regulation of RAS by GAPs R-HSA-5658442 8.366563e-01 0.077 0 0
PI3K Cascade R-HSA-109704 8.366563e-01 0.077 0 0
Signaling by FGFR2 in disease R-HSA-5655253 8.366563e-01 0.077 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 8.381300e-01 0.077 0 0
Apoptotic factor-mediated response R-HSA-111471 8.381300e-01 0.077 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 8.381300e-01 0.077 0 0
G-protein mediated events R-HSA-112040 8.434099e-01 0.074 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 8.445257e-01 0.073 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 8.445257e-01 0.073 0 0
PERK regulates gene expression R-HSA-381042 8.445257e-01 0.073 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 8.449381e-01 0.073 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 8.449381e-01 0.073 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 8.504602e-01 0.070 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 8.504602e-01 0.070 0 0
Crosslinking of collagen fibrils R-HSA-2243919 8.504602e-01 0.070 0 0
Pyrimidine biosynthesis R-HSA-500753 8.504602e-01 0.070 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 8.504602e-01 0.070 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 8.504602e-01 0.070 0 0
Translesion Synthesis by POLH R-HSA-110320 8.504602e-01 0.070 0 0
Diseases of hemostasis R-HSA-9671793 8.504602e-01 0.070 0 0
Other interleukin signaling R-HSA-449836 8.504602e-01 0.070 0 0
Specification of the neural plate border R-HSA-9834899 8.504602e-01 0.070 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 8.504602e-01 0.070 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 8.528529e-01 0.069 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 8.528529e-01 0.069 0 0
PRC2 methylates histones and DNA R-HSA-212300 8.537452e-01 0.069 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 8.537452e-01 0.069 0 0
Glycosphingolipid transport R-HSA-9845576 8.537452e-01 0.069 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.537452e-01 0.069 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 8.578871e-01 0.067 0 0
Amino acids regulate mTORC1 R-HSA-9639288 8.604128e-01 0.065 0 0
Meiotic synapsis R-HSA-1221632 8.604128e-01 0.065 0 0
Nucleotide biosynthesis R-HSA-8956320 8.604128e-01 0.065 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 8.618519e-01 0.065 0 0
Glycogen synthesis R-HSA-3322077 8.618519e-01 0.065 0 0
Co-inhibition by CTLA4 R-HSA-389513 8.618519e-01 0.065 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 8.618519e-01 0.065 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 8.618519e-01 0.065 0 0
Nephrin family interactions R-HSA-373753 8.618519e-01 0.065 0 0
Degradation of DVL R-HSA-4641258 8.624630e-01 0.064 0 0
Degradation of AXIN R-HSA-4641257 8.624630e-01 0.064 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 8.624630e-01 0.064 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 8.676296e-01 0.062 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 8.719036e-01 0.060 0 0
Leishmania phagocytosis R-HSA-9664417 8.719036e-01 0.060 0 0
Parasite infection R-HSA-9664407 8.719036e-01 0.060 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 8.723765e-01 0.059 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 8.723765e-01 0.059 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 8.723765e-01 0.059 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 8.723765e-01 0.059 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 8.723765e-01 0.059 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 8.723765e-01 0.059 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 8.723765e-01 0.059 0 0
Signalling to RAS R-HSA-167044 8.723765e-01 0.059 1 0
Interleukin-1 signaling R-HSA-9020702 8.764697e-01 0.057 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 8.784849e-01 0.056 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 8.784849e-01 0.056 0 0
Ion homeostasis R-HSA-5578775 8.810815e-01 0.055 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 8.820998e-01 0.054 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 8.820998e-01 0.054 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 8.820998e-01 0.054 0 0
Molybdenum cofactor biosynthesis R-HSA-947581 8.820998e-01 0.054 0 0
Serine metabolism R-HSA-977347 8.820998e-01 0.054 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 8.820998e-01 0.054 0 0
Assembly Of The HIV Virion R-HSA-175474 8.820998e-01 0.054 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.843896e-01 0.053 0 0
Diseases of Immune System R-HSA-5260271 8.858330e-01 0.053 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.858330e-01 0.053 0 0
IRS-mediated signalling R-HSA-112399 8.873401e-01 0.052 0 0
Platelet activation, signaling and aggregation R-HSA-76002 8.896379e-01 0.051 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 8.910828e-01 0.050 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 8.910828e-01 0.050 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 8.910828e-01 0.050 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 8.910828e-01 0.050 0 0
Signaling by KIT in disease R-HSA-9669938 8.910828e-01 0.050 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 8.910828e-01 0.050 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 8.910828e-01 0.050 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 8.910828e-01 0.050 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 8.927674e-01 0.049 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 8.927674e-01 0.049 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 8.927674e-01 0.049 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 8.927674e-01 0.049 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 8.927674e-01 0.049 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.927674e-01 0.049 0 0
Maturation of spike protein R-HSA-9694548 8.927674e-01 0.049 0 0
Protein ubiquitination R-HSA-8852135 8.932629e-01 0.049 0 0
Interleukin-12 signaling R-HSA-9020591 8.983972e-01 0.047 0 0
Intra-Golgi traffic R-HSA-6811438 8.993084e-01 0.046 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.993084e-01 0.046 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.993084e-01 0.046 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 8.993819e-01 0.046 0 0
Interleukin receptor SHC signaling R-HSA-912526 8.993819e-01 0.046 0 0
Formation of the ureteric bud R-HSA-9830674 8.993819e-01 0.046 0 0
Toll-like Receptor Cascades R-HSA-168898 9.021497e-01 0.045 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.033127e-01 0.044 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 9.054759e-01 0.043 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.054759e-01 0.043 0 0
Depyrimidination R-HSA-73928 9.054759e-01 0.043 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 9.070492e-01 0.042 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 9.070492e-01 0.042 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 9.070492e-01 0.042 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.070492e-01 0.042 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.070492e-01 0.042 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.095253e-01 0.041 0 0
Collagen degradation R-HSA-1442490 9.095253e-01 0.041 0 0
Defective pyroptosis R-HSA-9710421 9.112886e-01 0.040 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.112886e-01 0.040 0 0
Stimuli-sensing channels R-HSA-2672351 9.119874e-01 0.040 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.125163e-01 0.040 0 0
Cellular response to chemical stress R-HSA-9711123 9.132061e-01 0.039 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.141325e-01 0.039 0 0
Tight junction interactions R-HSA-420029 9.141325e-01 0.039 0 0
Acyl chain remodelling of PS R-HSA-1482801 9.141325e-01 0.039 0 0
Defects in cobalamin (B12) metabolism R-HSA-3296469 9.141325e-01 0.039 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 9.141325e-01 0.039 0 0
Hyaluronan degradation R-HSA-2160916 9.141325e-01 0.039 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 9.141325e-01 0.039 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.141325e-01 0.039 0 0
Signaling by PDGF R-HSA-186797 9.144143e-01 0.039 0 0
Proteasome assembly R-HSA-9907900 9.167648e-01 0.038 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.167648e-01 0.038 0 0
Signaling by FGFR2 R-HSA-5654738 9.168187e-01 0.038 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.190617e-01 0.037 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 9.190617e-01 0.037 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.206765e-01 0.036 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.206765e-01 0.036 0 0
Signaling by EGFR in Cancer R-HSA-1643713 9.206765e-01 0.036 0 0
TRP channels R-HSA-3295583 9.206765e-01 0.036 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 9.206765e-01 0.036 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 9.206765e-01 0.036 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.206765e-01 0.036 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.219221e-01 0.035 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.219221e-01 0.035 0 0
Somitogenesis R-HSA-9824272 9.219221e-01 0.035 0 0
IGF1R signaling cascade R-HSA-2428924 9.234775e-01 0.035 0 0
Insulin receptor signalling cascade R-HSA-74751 9.234775e-01 0.035 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 9.267221e-01 0.033 0 0
Cobalamin (Cbl) metabolism R-HSA-9759218 9.267221e-01 0.033 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 9.267221e-01 0.033 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.267221e-01 0.033 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 9.267221e-01 0.033 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 9.267221e-01 0.033 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 9.267221e-01 0.033 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 9.267771e-01 0.033 0 0
Diseases of DNA repair R-HSA-9675135 9.267771e-01 0.033 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.276716e-01 0.033 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.286124e-01 0.032 0 0
PPARA activates gene expression R-HSA-1989781 9.288199e-01 0.032 0 0
Signaling by Nuclear Receptors R-HSA-9006931 9.293776e-01 0.032 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 9.297594e-01 0.032 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.313461e-01 0.031 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.315792e-01 0.031 0 0
Telomere Extension By Telomerase R-HSA-171319 9.323073e-01 0.030 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 9.323073e-01 0.030 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 9.323073e-01 0.030 0 0
Pyroptosis R-HSA-5620971 9.323073e-01 0.030 0 0
Metal ion SLC transporters R-HSA-425410 9.356443e-01 0.029 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 9.357907e-01 0.029 0 0
Transmission across Chemical Synapses R-HSA-112315 9.365524e-01 0.028 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 9.374671e-01 0.028 0 0
DNA methylation R-HSA-5334118 9.374671e-01 0.028 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 9.374671e-01 0.028 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.374671e-01 0.028 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.388758e-01 0.027 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.390185e-01 0.027 0 0
Signaling by Interleukins R-HSA-449147 9.390620e-01 0.027 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 9.422339e-01 0.026 0 0
Neurotransmitter clearance R-HSA-112311 9.422339e-01 0.026 0 0
PI Metabolism R-HSA-1483255 9.435852e-01 0.025 0 0
Pyruvate metabolism R-HSA-70268 9.449522e-01 0.025 0 0
Interleukin-12 family signaling R-HSA-447115 9.449522e-01 0.025 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.466376e-01 0.024 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 9.466376e-01 0.024 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.466376e-01 0.024 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.470585e-01 0.024 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 9.488450e-01 0.023 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.504144e-01 0.022 0 0
ER-Phagosome pathway R-HSA-1236974 9.504716e-01 0.022 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.535666e-01 0.021 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 9.544641e-01 0.020 0 0
Regulation of necroptotic cell death R-HSA-5675482 9.544641e-01 0.020 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.565266e-01 0.019 0 0
Signaling by ERBB4 R-HSA-1236394 9.569308e-01 0.019 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.579361e-01 0.019 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.579361e-01 0.019 0 0
Interleukin-1 family signaling R-HSA-446652 9.581590e-01 0.019 0 0
G alpha (z) signalling events R-HSA-418597 9.593054e-01 0.018 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.593880e-01 0.018 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.601031e-01 0.018 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.611435e-01 0.017 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.611435e-01 0.017 0 0
Hyaluronan metabolism R-HSA-2142845 9.611435e-01 0.017 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.611435e-01 0.017 0 0
NOD1/2 Signaling Pathway R-HSA-168638 9.611435e-01 0.017 1 1
NPAS4 regulates expression of target genes R-HSA-9768919 9.611435e-01 0.017 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.619135e-01 0.017 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.641065e-01 0.016 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.641065e-01 0.016 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.641065e-01 0.016 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.641065e-01 0.016 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.641065e-01 0.016 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 9.641196e-01 0.016 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.652699e-01 0.015 0 0
Integrin cell surface interactions R-HSA-216083 9.659927e-01 0.015 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.666562e-01 0.015 0 0
GPVI-mediated activation cascade R-HSA-114604 9.668438e-01 0.015 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.668438e-01 0.015 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 9.674218e-01 0.014 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 9.674218e-01 0.014 0 0
Cellular response to starvation R-HSA-9711097 9.677219e-01 0.014 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.677219e-01 0.014 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.678300e-01 0.014 0 0
Peroxisomal protein import R-HSA-9033241 9.688092e-01 0.014 0 0
Voltage gated Potassium channels R-HSA-1296072 9.693724e-01 0.014 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 9.693724e-01 0.014 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.695480e-01 0.013 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 9.705967e-01 0.013 0 0
Metabolism of polyamines R-HSA-351202 9.708279e-01 0.013 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.717084e-01 0.012 0 0
Elastic fibre formation R-HSA-1566948 9.717084e-01 0.012 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 9.717084e-01 0.012 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.720743e-01 0.012 0 0
Nucleotide salvage R-HSA-8956321 9.727202e-01 0.012 0 0
Signaling by FGFR R-HSA-190236 9.727299e-01 0.012 0 0
Pentose phosphate pathway R-HSA-71336 9.738663e-01 0.012 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.738663e-01 0.012 0 0
RAS processing R-HSA-9648002 9.738663e-01 0.012 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.738663e-01 0.012 0 0
Mitochondrial protein import R-HSA-1268020 9.744938e-01 0.011 0 0
ABC-family proteins mediated transport R-HSA-382556 9.755983e-01 0.011 0 0
Glycogen metabolism R-HSA-8982491 9.758597e-01 0.011 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.758597e-01 0.011 0 0
Generation of second messenger molecules R-HSA-202433 9.758597e-01 0.011 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.758597e-01 0.011 0 0
Interleukin-2 family signaling R-HSA-451927 9.758597e-01 0.011 0 0
Post-translational protein modification R-HSA-597592 9.772636e-01 0.010 0 0
Meiosis R-HSA-1500620 9.776780e-01 0.010 0 0
Ion transport by P-type ATPases R-HSA-936837 9.777125e-01 0.010 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.794024e-01 0.009 0 0
Heme biosynthesis R-HSA-189451 9.794024e-01 0.009 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.802402e-01 0.009 0 0
Opioid Signalling R-HSA-111885 9.805052e-01 0.009 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.805052e-01 0.009 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.805363e-01 0.009 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 9.806225e-01 0.008 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.809738e-01 0.008 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 9.809738e-01 0.008 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.809738e-01 0.008 0 0
Extracellular matrix organization R-HSA-1474244 9.812053e-01 0.008 0 0
Signaling by FGFR4 R-HSA-5654743 9.824254e-01 0.008 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.824254e-01 0.008 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.828076e-01 0.008 0 0
Regulated Necrosis R-HSA-5218859 9.830117e-01 0.007 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.837664e-01 0.007 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.837664e-01 0.007 0 0
Downstream TCR signaling R-HSA-202424 9.845474e-01 0.007 0 0
Signaling by FGFR3 R-HSA-5654741 9.850051e-01 0.007 0 0
COPII-mediated vesicle transport R-HSA-204005 9.851802e-01 0.006 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.861494e-01 0.006 0 0
Interferon gamma signaling R-HSA-877300 9.861821e-01 0.006 0 0
TCR signaling R-HSA-202403 9.869273e-01 0.006 0 0
Infectious disease R-HSA-5663205 9.869726e-01 0.006 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.871713e-01 0.006 0 0
Signaling by Insulin receptor R-HSA-74752 9.871713e-01 0.006 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.871713e-01 0.006 0 0
Synthesis of PC R-HSA-1483191 9.872064e-01 0.006 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.879466e-01 0.005 0 0
Gluconeogenesis R-HSA-70263 9.881828e-01 0.005 0 0
Neuronal System R-HSA-112316 9.882497e-01 0.005 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.883552e-01 0.005 0 0
Mitochondrial protein degradation R-HSA-9837999 9.886767e-01 0.005 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.890848e-01 0.005 0 0
Hemostasis R-HSA-109582 9.891655e-01 0.005 0 0
rRNA processing R-HSA-72312 9.892797e-01 0.005 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 9.892949e-01 0.005 0 0
Neutrophil degranulation R-HSA-6798695 9.897955e-01 0.004 0 0
Reproduction R-HSA-1474165 9.898662e-01 0.004 0 0
Complex IV assembly R-HSA-9864848 9.906875e-01 0.004 0 0
The phototransduction cascade R-HSA-2514856 9.906875e-01 0.004 0 0
Translation of Structural Proteins R-HSA-9694635 9.908463e-01 0.004 0 0
Metabolism of nucleotides R-HSA-15869 9.909866e-01 0.004 0 0
Interferon alpha/beta signaling R-HSA-909733 9.913028e-01 0.004 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.914590e-01 0.004 0 0
Interleukin-10 signaling R-HSA-6783783 9.914590e-01 0.004 0 0
ABC transporter disorders R-HSA-5619084 9.914590e-01 0.004 0 0
Neddylation R-HSA-8951664 9.918307e-01 0.004 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.920316e-01 0.003 0 0
Ion channel transport R-HSA-983712 9.926892e-01 0.003 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 9.931662e-01 0.003 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.931845e-01 0.003 0 0
Paracetamol ADME R-HSA-9753281 9.932219e-01 0.003 0 0
Signaling by FGFR1 R-HSA-5654736 9.937395e-01 0.003 0 0
Ribosome-associated quality control R-HSA-9948299 9.938553e-01 0.003 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.939693e-01 0.003 0 0
Leishmania infection R-HSA-9658195 9.943798e-01 0.002 0 0
Parasitic Infection Pathways R-HSA-9824443 9.943798e-01 0.002 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 9.945887e-01 0.002 0 0
Formation of the cornified envelope R-HSA-6809371 9.949035e-01 0.002 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.950670e-01 0.002 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.951172e-01 0.002 0 0
tRNA Aminoacylation R-HSA-379724 9.954438e-01 0.002 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.954438e-01 0.002 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 9.956370e-01 0.002 0 0
Peptide chain elongation R-HSA-156902 9.960409e-01 0.002 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.961132e-01 0.002 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.963555e-01 0.002 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.967960e-01 0.001 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 9.970147e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.972205e-01 0.001 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.973877e-01 0.001 0 0
Kidney development R-HSA-9830369 9.973877e-01 0.001 0 0
Adaptive Immune System R-HSA-1280218 9.975355e-01 0.001 0 0
Formation of a pool of free 40S subunits R-HSA-72689 9.979063e-01 0.001 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.979420e-01 0.001 0 0
Disease R-HSA-1643685 9.979421e-01 0.001 0 0
Potassium Channels R-HSA-1296071 9.980502e-01 0.001 0 0
ECM proteoglycans R-HSA-3000178 9.980993e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.980993e-01 0.001 0 0
Metabolism of porphyrins R-HSA-189445 9.980993e-01 0.001 0 0
Regulation of insulin secretion R-HSA-422356 9.983093e-01 0.001 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.983787e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.985027e-01 0.001 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.986171e-01 0.001 0 0
Iron uptake and transport R-HSA-917937 9.986171e-01 0.001 0 0
Cholesterol biosynthesis R-HSA-191273 9.989107e-01 0.000 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 9.990709e-01 0.000 0 0
Platelet homeostasis R-HSA-418346 9.991131e-01 0.000 0 0
Amyloid fiber formation R-HSA-977225 9.991419e-01 0.000 0 0
Translation R-HSA-72766 9.992289e-01 0.000 0 0
Cardiac conduction R-HSA-5576891 9.993122e-01 0.000 0 0
Protein localization R-HSA-9609507 9.993393e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.994217e-01 0.000 0 0
Integration of energy metabolism R-HSA-163685 9.995413e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.995997e-01 0.000 0 0
Neurotransmitter release cycle R-HSA-112310 9.996128e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.996128e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.997184e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.997492e-01 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.997514e-01 0.000 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 9.997599e-01 0.000 0 0
Eukaryotic Translation Termination R-HSA-72764 9.997783e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.998332e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.998388e-01 0.000 0 0
Selenocysteine synthesis R-HSA-2408557 9.998625e-01 0.000 0 0
Viral mRNA Translation R-HSA-192823 9.998828e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.998828e-01 0.000 0 0
Immune System R-HSA-168256 9.999192e-01 0.000 1 0
Bile acid and bile salt metabolism R-HSA-194068 9.999380e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999428e-01 0.000 0 0
G alpha (q) signalling events R-HSA-416476 9.999626e-01 0.000 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.999645e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.999698e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999773e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999780e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.999787e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999822e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999876e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999893e-01 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 9.999920e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999921e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999955e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.999962e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.999962e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999963e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999976e-01 0.000 1 0
SLC-mediated transmembrane transport R-HSA-425407 9.999979e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999980e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999987e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.999989e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.999991e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999995e-01 0.000 0 0
G alpha (s) signalling events R-HSA-418555 9.999997e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999998e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999998e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999999e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999999e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999999e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
G alpha (i) signalling events R-HSA-418594 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
GPCR downstream signalling R-HSA-388396 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Signaling by GPCR R-HSA-372790 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways