P38B
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0MZ66 | S444 | Sugiyama | SHTN1 KIAA1598 | RPVNQTARPKTKPESSKGCEsAVDELKGILGtLNKSTSSRs |
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| A6NMY6 | T19 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | __MstVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDA |
| A6NMY6 | Y24 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | VHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEt |
| O00115 | S70 | Sugiyama | DNASE2 DNASE2A DNL2 | QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL |
| O00232 | S335 | Sugiyama | PSMD12 | MRWSTLVEDYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLK |
| O00418 | S396 | iPTMNet|PSP | EEF2K | LsENSGDENMSDVTFDsLPSsPsSATPHSQKLDHLHWPVFS |
| O14497 | S363 | Sugiyama | ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 | AAAAAAASGGAQQRsHHAPMsPGssGGGGQPLARtPQPssP |
| O14545 | T323 | Sugiyama | TRAFD1 FLN29 | ELLIDHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQNFLQ |
| O14672 | S630 | Sugiyama | ADAM10 KUZ MADM | TGSVQWSRHFSGRTITLQPGsPCNDFRGYCDVFMRCRLVDA |
| O14745 | S280 | Sugiyama | NHERF1 NHERF SLC9A3R1 | tNGEIQKENsREALAEAALEsPRPALVRsAssDtsEELNsQ |
| O14910 | S130 | Sugiyama | LIN7A MALS1 VELI1 | ELPKTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLK |
| O43521 | S69 | SIGNOR | BCL2L11 BIM | GGEGDSCPHGsPQGPLAPPAsPGPFATRsPLFIFMRRSsLL |
| O43707 | T615 | Sugiyama | ACTN4 | QRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPKRDH |
| O43707 | Y611 | Sugiyama | ACTN4 | HKEAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVP |
| O43852 | T65 | Sugiyama | CALU | FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD |
| O60333 | T647 | Sugiyama | KIF1B KIAA0591 KIAA1448 | GKNHVFRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELL |
| O60333 | T652 | Sugiyama | KIF1B KIAA0591 KIAA1448 | FRFNHPEQARAEREKtPsAEtPsEPVDWTFAQRELLEKQGI |
| O60361 | Y136 | Sugiyama | NME2P1 | SLRFKPEELVDYKSCAHDWVyE___________________ |
| O60381 | S402 | SIGNOR|ELM|iPTMNet|EPSD | HBP1 | sCGGPGGQDFARSGFSKNCGsPGSSQLSSNSLYAKAVKNHs |
| O60664 | S91 | Sugiyama | PLIN3 M6PRBP1 TIP47 | TAAAVsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQ |
| O75179 | S2042 | Sugiyama | ANKRD17 GTAR KIAA0697 | TAPTNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPLD |
| O75179 | S2045 | Sugiyama | ANKRD17 GTAR KIAA0697 | TNATYPMPTAKEHyPVssPssPsPPAQPGGVsRNsPLDCGs |
| O75391 | S158 | Sugiyama | SPAG7 | LKELAQRQEEEAAQQGPVVVsPAsDyKDKYSHLIGKGAAKD |
| O75582 | S360 | SIGNOR | RPS6KA5 MSK1 | RDELDVsNFAEEFtEMDPtYsPAALPQssEKLFQGYsFVAP |
| O75582 | T581 | SIGNOR | RPS6KA5 MSK1 | IKIIDFGFARLKPPDNQPLKtPCFTLHYAAPELLNQNGYDE |
| O75582 | T700 | SIGNOR | RPS6KA5 MSK1 | GLRYNEWLQDGSQLSSNPLMtPDILGSSGAAVHTCVKAtFH |
| O75821 | T190 | Sugiyama | EIF3G EIF3S4 | PYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNKt |
| O75928 | S113 | SIGNOR | PIAS2 PIASX | EPDLAVAGIHSLPSTSVTPHsPSsPVGSVLLQDTKPTFEMQ |
| O75928 | S116 | SIGNOR | PIAS2 PIASX | LAVAGIHSLPSTSVTPHsPSsPVGSVLLQDTKPTFEMQQPS |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P00338 | T309 | Sugiyama | LDHA PIG19 | LSVPCILGQNGISDLVKVTLtsEEEARLKKsADtLWGIQKE |
| P00367 | T409 | Sugiyama | GLUD1 GLUD | TKSNAPRVKAKIIAEGANGPttPEADKIFLERNIMVIPDLY |
| P00533 | S1039 | PSP | EGFR ERBB ERBB1 HER1 | PQQGFFssPStsRTPLLssLsAtsNNstVACIDRNGLQsCP |
| P00533 | T1041 | PSP | EGFR ERBB ERBB1 HER1 | QGFFssPStsRTPLLssLsAtsNNstVACIDRNGLQsCPIK |
| P00558 | S393 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA |
| P00558 | T168 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF |
| P00558 | T369 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV |
| P00558 | T376 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG |
| P00558 | T378 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA |
| P00558 | T394 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | T37 | Sugiyama | ALDOA ALDA | sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR |
| P04083 | S170 | Sugiyama | ANXA1 ANX1 LPC1 | RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE |
| P04083 | S189 | Sugiyama | ANXA1 ANX1 LPC1 | tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA |
| P04083 | S34 | Sugiyama | ANXA1 ANX1 LPC1 | IENEEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKA |
| P04083 | S37 | Sugiyama | ANXA1 ANX1 LPC1 | EEQEyVQtVKssKGGPGsAVsPyPtFNPssDVAALHKAIMV |
| P04083 | T169 | Sugiyama | ANXA1 ANX1 LPC1 | IRDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRs |
| P04083 | T172 | Sugiyama | ANXA1 ANX1 LPC1 | INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF |
| P04150 | S226 | PSP | NR3C1 GRL | KETNEsPWRSDLLIDENCLLsPLAGEDDSFLLEGNSNEDCK |
| P04179 | S106 | PSP | SOD2 | PALKFNGGGHINHSIFWTNLsPNGGGEPKGELLEAIKRDFG |
| P04179 | T79 | PSP | SOD2 | VNNLNVTEEKYQEALAKGDVtAQIALQPALKFNGGGHINHS |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S79 | Sugiyama | RPLP2 D11S2243E RPP2 | IGKLAsVPAGGAVAVsAAPGsAAPAAGsAPAAAEEKKDEKK |
| P05387 | S86 | Sugiyama | RPLP2 D11S2243E RPP2 | PAGGAVAVsAAPGsAAPAAGsAPAAAEEKKDEKKEEsEEsD |
| P05787 | S74 | SIGNOR | KRT8 CYK8 | YGGASGMGGITAVtVNQSLLsPLVLEVDPNIQAVRTQEKEQ |
| P06733 | S263 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GMDVAASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsF |
| P06733 | S272 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | T19 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T26 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | Y270 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV |
| P06733 | Y280 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD |
| P06744 | S455 | Sugiyama | GPI | ALMRGKSTEEARKELQAAGKsPEDLERLLPHKVFEGNRPTN |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T302 | Sugiyama | LDHB | YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD |
| P07205 | S393 | Sugiyama | PGK2 PGKB | GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA |
| P07205 | T168 | Sugiyama | PGK2 PGKB | EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF |
| P07205 | T394 | Sugiyama | PGK2 PGKB | GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL |
| P07237 | S88 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG |
| P07237 | T428 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | DKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFPA |
| P07237 | Y94 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK |
| P07355 | T19 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | __MstVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDA |
| P07355 | Y24 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | VHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEt |
| P07437 | S75 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| P07437 | T72 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| P07814 | T737 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | EKTKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRV |
| P07814 | T746 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | NETSAPFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVRE |
| P07814 | Y1504 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | KPLCELQPGAKCVCGKNPAKyytLFGRsy____________ |
| P07814 | Y1505 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PLCELQPGAKCVCGKNPAKyytLFGRsy_____________ |
| P07858 | S216 | Sugiyama | CTSB CPSB | PPCTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSE |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S164 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGT |
| P07900 | S165 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK |
| P07900 | S391 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | T317 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P07954 | T90 | SIGNOR | FH | AQTVRsTMNFKIGGVTERMPtPVIKAFGILKRAAAEVNQDy |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | S607 | Sugiyama | SLC3A2 MDU1 | ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP |
| P08238 | S159 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | VAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGT |
| P08238 | S160 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK |
| P08238 | S383 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | T309 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | T83 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sKLDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLG |
| P08238 | T85 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI |
| P08238 | T89 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG |
| P08238 | Y484 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR |
| P08238 | Y485 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK |
| P08708 | S89 | Sugiyama | RPS17 RPS17L | ISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKEMLKLL |
| P08865 | T97 | Sugiyama | RPSA LAMBR LAMR1 | IssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQAAFR |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P10415 | S87 | SIGNOR | BCL2 | ARtsPLQtPAAPGAAAGPALsPVPPVVHLTLRQAGDDFSRR |
| P10636 | T548 | SIGNOR | MAPT MAPTL MTBT1 TAU | RtPsLPtPPTREPKKVAVVRtPPKsPssAKSRLQTAPVPMP |
| P10721 | S943 | Sugiyama | KIT SCFR | LIEKQISEstNHIysNLANCsPNRQKPVVDHSVRINsVGst |
| P10721 | Y936 | Sugiyama | KIT SCFR | TFKQIVQLIEKQISEstNHIysNLANCsPNRQKPVVDHSVR |
| P10809 | S175 | Sugiyama | HSPD1 HSP60 | LKKQsKPVttPEEIAQVAtIsANGDKEIGNIIsDAMKKVGR |
| P10809 | S70 | Sugiyama | HSPD1 HSP60 | AVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLKDKY |
| P10809 | T115 | Sugiyama | HSPD1 HSP60 | AKLVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISKGA |
| P10809 | T164 | Sugiyama | HSPD1 HSP60 | VMLAVDAVIAELKKQsKPVttPEEIAQVAtIsANGDKEIGN |
| P10809 | T455 | Sugiyama | HSPD1 HSP60 | GIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLKIP |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | T37 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P11142 | T38 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P11142 | T45 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P12270 | S2155 | Sugiyama | TPR | PstPtLVVPHRtDGFAEAIHsPQVAGVPRFRFGPPEDMPQT |
| P12277 | T35 | Sugiyama | CKB CKBB | PAEDEFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDD |
| P12277 | Y39 | Sugiyama | CKB CKBB | EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT |
| P13051 | S64 | Sugiyama | UNG DGU UNG1 UNG15 | AAIPAKKAPAGQEEPGtPPssPLsAEQLDRIQRNKAAALLR |
| P13051 | T60 | Sugiyama | UNG DGU UNG1 UNG15 | SGDAAAIPAKKAPAGQEEPGtPPssPLsAEQLDRIQRNKAA |
| P13639 | S732 | Sugiyama | EEF2 EF2 | DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP |
| P13639 | T735 | Sugiyama | EEF2 EF2 | HRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCPEQV |
| P13804 | S192 | Sugiyama | ETFA | sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL |
| P13807 | S645 | PSP | GYS1 GYS | PNEADAAQGyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRN |
| P13807 | S653 | PSP | GYS1 GYS | GyRyPRPAsVPPsPsLsRHssPHQsEDEEDPRNGPLEEDGE |
| P13807 | S727 | PSP|Sugiyama | GYS1 GYS | KRNsVDtAtsssLstPsEPLsPtssLGEERN__________ |
| P13807 | T721 | PSP | GYS1 GYS | sSTSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN____ |
| P14314 | S108 | Sugiyama | PRKCSH G19P1 | PSNRVNDGVCDCCDGtDEyNsGVICENtCKEKGRKEREsLQ |
| P14314 | T469 | Sugiyama | PRKCSH G19P1 | WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S552 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | KEKQDKIyFMAGsSRKEAEssPFVERLLKKGyEVIyLTEPV |
| P14866 | S101 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | GAAGGGGGGENyDDPHKtPAsPVVHIRGLIDGVVEADLVEA |
| P15336 | T69 | PSP|Sugiyama | ATF2 CREB2 CREBP1 | HEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELA |
| P15336 | T71 | PSP|Sugiyama | ATF2 CREB2 CREBP1 | MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP |
| P15531 | S125 | Sugiyama | NME1 NDPKA NM23 | RGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDyTsC |
| P15559 | S82 | Sugiyama | NQO1 DIA4 NMOR1 | DPANFQYPAESVLAYKEGHLsPDIVAEQKKLEAADLVIFQF |
| P15923 | S139 | SIGNOR | TCF3 BHLHB21 E2A ITF1 | GLTQAGFLSGELALNSPGPLsPsGMKGTSQYYPSYsGssRR |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17544 | T51 | PSP|Sugiyama | ATF7 ATFA | HEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELA |
| P17544 | T53 | Sugiyama | ATF7 ATFA | MTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASS |
| P17812 | S573 | Sugiyama | CTPS1 CTPS | HYLQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD__ |
| P17812 | S575 | Sugiyama | CTPS1 CTPS | LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____ |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18669 | S31 | Sugiyama | PGAM1 PGAMA CDABP0006 | HGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALRDAGyE |
| P18754 | S125 | Sugiyama | RCC1 CHC1 | VEGSEMVPGKVELQEKVVQVsAGDsHtAALTDDGRVFLWGS |
| P18754 | S129 | Sugiyama | RCC1 CHC1 | EMVPGKVELQEKVVQVsAGDsHtAALTDDGRVFLWGSFRDN |
| P18754 | T131 | Sugiyama | RCC1 CHC1 | VPGKVELQEKVVQVsAGDsHtAALTDDGRVFLWGSFRDNNG |
| P20290 | T182 | Sugiyama | BTF3 NACB OK/SW-cl.8 | LRRLAEALPKQsVDGKAPLAtGEDDDDEVPDLVENFDEAsK |
| P21333 | S1081 | Sugiyama | FLNA FLN FLN1 | AVAPTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLG |
| P21333 | S1084 | Sugiyama | FLNA FLN FLN1 | PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV |
| P22234 | S27 | Sugiyama | PAICS ADE2 AIRC PAIS | LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK |
| P22314 | T233 | Sugiyama | UBA1 A1S9T UBE1 | GEQPLSAMVSMVTKDNPGVVtCLDEARHGFESGDFVSFSEV |
| P22392 | Y151 | Sugiyama | NME2 NM23B | SLWFKPEELVDyKSCAHDWVyE___________________ |
| P22626 | S259 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GFGDGyNGyGGGPGGGNFGGsPGyGGGRGGYGGGGPGYGNQ |
| P23396 | T221 | Sugiyama | RPS3 OK/SW-cl.26 | KKPLPDHVsIVEPKDEILPttPIsEQKGGKPEPPAMPQPVP |
| P23396 | T242 | Sugiyama | RPS3 OK/SW-cl.26 | PIsEQKGGKPEPPAMPQPVPtA___________________ |
| P23528 | Y140 | Sugiyama | CFL1 CFL | SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs |
| P25398 | Y127 | Sugiyama | RPS12 | sCVVVKDYGKESQAKDVIEEyFKCKK_______________ |
| P25705 | T64 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | QKtGtAEMssILEERILGADtsVDLEETGRVLsIGDGIARV |
| P25786 | S14 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | _______MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQGSA |
| P26232 | S667 | Sugiyama | CTNNA2 CAPR | YDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEEKAKIAEQV |
| P26373 | T148 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV |
| P26373 | T151 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE |
| P27348 | Y48 | Sugiyama | YWHAQ | AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK |
| P27708 | S1038 | Sugiyama | CAD | QLPNNMAMALHRQQCRVLGtsPEAIDSAENRFKFSRLLDTI |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P27824 | S362 | Sugiyama | CANX | WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK |
| P28066 | S172 | Sugiyama | PSMA5 | QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK |
| P28066 | S179 | Sugiyama | PSMA5 | sGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSL |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | S548 | Sugiyama | TKT | NIRVLDPFTIKPLDRKLILDsARAtKGRILTVEDHYYEGGI |
| P29401 | T287 | Sugiyama | TKT | AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP |
| P29401 | T444 | Sugiyama | TKT | DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT |
| P29692 | S70 | Sugiyama | EEF1D EF1D | IARARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVE |
| P29692 | S71 | Sugiyama | EEF1D EF1D | ARARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVEN |
| P29692 | T147 | Sugiyama | EEF1D EF1D | PQtQHVsPMRQVEPPAKKPAtPAEDDEDDDIDLFGsDNEEE |
| P29692 | T73 | Sugiyama | EEF1D EF1D | ARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVENQs |
| P29966 | S101 | Sugiyama | MARCKS MACS PRKCSL | sPsAAEKGEPAAAAAPEAGAsPVEKEAPAEGEAAEPGsPtA |
| P29966 | S26 | Sugiyama | MARCKS MACS PRKCSL | SKTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAs |
| P29966 | S81 | Sugiyama | MARCKS MACS PRKCSL | NGsAPAADKEEPAAAGsGAAsPsAAEKGEPAAAAAPEAGAs |
| P30041 | T44 | Sugiyama | PRDX6 AOP2 KIAA0106 | RFHDFLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKR |
| P30041 | T48 | Sugiyama | PRDX6 AOP2 KIAA0106 | FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30050 | S157 | Sugiyama | RPL12 | QsVGCNVDGRHPHDIIDDINsGAVECPAs____________ |
| P30050 | S165 | Sugiyama | RPL12 | GRHPHDIIDDINsGAVECPAs____________________ |
| P30050 | T135 | Sugiyama | RPL12 | QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI |
| P30101 | S443 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | LsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLN |
| P30101 | T437 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KELGEKLsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsP |
| P30281 | T283 | PSP | CCND3 | ssPAPKAPRGsssQGPsQtstPtDVtAIHL___________ |
| P30305 | S101 | SIGNOR | CDC25B CDC25HU2 | SRSRLTHLsLsRRASESSLSsEsSESSDAGLCMDSPSPMDP |
| P30305 | S103 | SIGNOR | CDC25B CDC25HU2 | SRLTHLsLsRRASESSLSsEsSESSDAGLCMDSPSPMDPHM |
| P30305 | S249 | PSP | CDC25B CDC25HU2 | ssAPDLMCLsPDRKMEVEELsPLALGRFSLTPAEGDtEEDD |
| P30305 | S323 | SIGNOR | CDC25B CDC25HU2 | KEEEKDLVMYSKCQRLFRsPsMPCSVIRPILKRLERPQDRD |
| P30305 | S375 | SIGNOR | CDC25B CDC25HU2 | tPPEEQQEAEEPKARVLRsKsLCHDEIENLLDSDHRELIGD |
| P30307 | S216 | SIGNOR | CDC25C | EFsLKDQEAKVSRsGLYRsPsMPENLNRPRLKQVEKFKDNt |
| P30405 | T74 | Sugiyama | PPIF CYP3 | ANGKPLGRVVLELKADVVPKtAENFRALCTGEKGFGYKGST |
| P31150 | S316 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM |
| P31150 | T311 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | VRKAGQVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSD |
| P31327 | T45 | Sugiyama | CPS1 | AHQKWKFSRPGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPS |
| P31939 | S300 | Sugiyama | ATIC PURH OK/SW-cl.86 | sEDEAKVCMVyDLyKTLtPIsAAyARARGADRMssFGDFVA |
| P31939 | T297 | Sugiyama | ATIC PURH OK/SW-cl.86 | IPLsEDEAKVCMVyDLyKTLtPIsAAyARARGADRMssFGD |
| P31943 | S104 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P31943 | T107 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | KSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSKEEI |
| P31946 | Y50 | Sugiyama | YWHAB | AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK |
| P31947 | Y48 | Sugiyama | SFN HME1 | GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK |
| P34897 | S417 | Sugiyama | SHMT2 | ERVLELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFR |
| P34897 | T420 | Sugiyama | SHMT2 | LELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFREDD |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34931 | T39 | Sugiyama | HSPA1L | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P34931 | T40 | Sugiyama | HSPA1L | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P34931 | T47 | Sugiyama | HSPA1L | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P35221 | S668 | Sugiyama | CTNNA1 | FDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEQKAKIAEQV |
| P35611 | S358 | Sugiyama | ADD1 ADDA | PDNLVLLNPEKYKAKsRsPGsPVGEGtGsPPKWQIGEQEFE |
| P35637 | S346 | Sugiyama | FUS TLS | TDRETGKLKGEAtVsFDDPPsAKAAIDWFDGKEFsGNPIKV |
| P35638 | S79 | ELM | DDIT3 CHOP CHOP10 GADD153 | SLAWLTEEEPEPAEVTSTSQsPHsPDSSQSSLAQEEEEEDQ |
| P35638 | S82 | ELM | DDIT3 CHOP CHOP10 GADD153 | WLTEEEPEPAEVTSTSQsPHsPDSSQSSLAQEEEEEDQGRT |
| P35900 | S13 | SIGNOR | KRT20 | ________MDFSRRSFHRSLsSSLQAPVVSTVGMQRLGTTP |
| P36578 | S295 | Sugiyama | RPL4 RPL1 | sNyNLPMHKMINtDLsRILKsPEIQRALRAPRKKIHRRVLK |
| P36956 | S63 | PSP | SREBF1 BHLHD1 SREBP1 | FPGLFDPPYAGSGAGGtDPAsPDTSSPGSLSPPPATLSSSL |
| P36956 | T426 | PSP | SREBF1 BHLHD1 SREBP1 | SGGNTDVLMEGVKTEVEDTLtPPPsDAGsPFQSsPLSLGSR |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S549 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T86 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK |
| P38646 | T87 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR |
| P38646 | T94 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN |
| P39019 | Y48 | Sugiyama | RPS19 | LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P40222 | S514 | Sugiyama | TXLNA TXLN | GsLtDsGPERRPEGPGAQAPssPRVtEAPCyPGAPSTEASG |
| P41091 | T109 | Sugiyama | EIF2S3 EIF2G | YKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVRH |
| P41235 | S167 | SIGNOR|ELM|iPTMNet|EPSD|PSP | HNF4A HNF4 NR2A1 TCF14 | ssLPsINALLQAEVLSRQItsPVSGINGDIRAKKIASIADV |
| P42166 | T160 | Sugiyama | TMPO LAP2 | KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs |
| P42167 | T160 | Sugiyama | TMPO LAP2 | KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS |
| P42677 | S11 | Sugiyama | RPS27 MPS1 | __________MPLAKDLLHPsPEEEKRKHKKKRLVQsPNsy |
| P46013 | S308 | Sugiyama | MKI67 | VSRKSRPKsGGsGHAVAEPAsPEQELDQNKGKGRDVEsVQt |
| P46063 | S63 | Sugiyama | RECQL RECQ1 RECQL1 | TKKIKQCLEDsDAGAsNEyDssPAAWNKEDFPWSGKVKDIL |
| P46777 | S176 | Sugiyama | RPL5 MSTP030 | GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR |
| P46783 | S146 | Sugiyama | RPS10 | TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_ |
| P46937 | S289 | Sugiyama | YAP1 YAP65 | MNQRIsQsAPVKQPPPLAPQsPQGGVMGGsNsNQQQQMRLQ |
| P46937 | T119 | Sugiyama | YAP1 YAP65 | PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP |
| P46940 | T1405 | Sugiyama | IQGAP1 KIAA0051 | LLNTKRLIVDVIRFQPGETLtEILEtPAtsEQEAEHQRAMQ |
| P46940 | T1410 | Sugiyama | IQGAP1 KIAA0051 | RLIVDVIRFQPGETLtEILEtPAtsEQEAEHQRAMQRRAIR |
| P46940 | T1413 | Sugiyama | IQGAP1 KIAA0051 | VDVIRFQPGETLtEILEtPAtsEQEAEHQRAMQRRAIRDAK |
| P47756 | S207 | Sugiyama | CAPZB | MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst |
| P47914 | S142 | Sugiyama | RPL29 | KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___ |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P49321 | S659 | Sugiyama | NASP | IEELKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsst |
| P49321 | T390 | Sugiyama | NASP | EAPVLPKDGAVNGPsVVGDQtPIEPQtsIERLtEtKDGsGL |
| P49411 | T74 | Sugiyama | TUFM | YVRDKPHVNVGTIGHVDHGKtTLTAAITKILAEGGGAKFKK |
| P49448 | T409 | Sugiyama | GLUD2 GLUDP1 | TKSNAPRVKAKIIAEGANGPttPEADKIFLERNILVIPDLY |
| P50395 | S316 | Sugiyama | GDI2 RABGDIB | QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM |
| P50395 | T311 | Sugiyama | GDI2 RABGDIB | VEKVGQVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSD |
| P50502 | S181 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | LQKPNAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| P50552 | T335 | Sugiyama | VASP | tTLPRMKssssVttsEtQPCtPsSSDySDLQRVKQELLEEV |
| P50991 | T50 | Sugiyama | CCT4 CCTD SRB | PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI |
| P52597 | S104 | Sugiyama | HNRNPF HNRPF | EVFKSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTK |
| P52597 | S107 | Sugiyama | HNRNPF HNRPF | KSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTKEEI |
| P52948 | S623 | Sugiyama | NUP98 ADAR2 | KNLNNsNLFsPVNRDsENLAsPsEyPENGERFsFLSKPVDE |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T38 | Sugiyama | HSPA2 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P54652 | T39 | Sugiyama | HSPA2 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P54652 | T46 | Sugiyama | HSPA2 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P55060 | T341 | Sugiyama | CSE1L CAS XPO2 | LASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEA |
| P55795 | S104 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P55795 | T107 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | KSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSKEEI |
| P60174 | S80 | Sugiyama | TPI1 TPI | IAVAAQNCyKVTNGAFtGEIsPGMIKDCGAtWVVLGHsERR |
| P60174 | T214 | Sugiyama | TPI1 TPI | KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60174 | T46 | Sugiyama | TPI1 TPI | IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN |
| P60174 | T76 | Sugiyama | TPI1 TPI | LDPKIAVAAQNCyKVTNGAFtGEIsPGMIKDCGAtWVVLGH |
| P60174 | Y48 | Sugiyama | TPI1 TPI | tLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQNCy |
| P60660 | T22 | Sugiyama | MYL6 | CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN |
| P60660 | Y89 | Sugiyama | MYL6 | HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI |
| P60709 | T106 | Sugiyama | ACTB | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P60709 | T318 | Sugiyama | ACTB | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61254 | T8 | Sugiyama | RPL26 | _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK |
| P61758 | T45 | Sugiyama | VBP1 PFDN3 | IPEAVFVEDVDSFMKQPGNEtADtVLKKLDEQYQKYKFMEL |
| P61758 | T48 | Sugiyama | VBP1 PFDN3 | AVFVEDVDSFMKQPGNEtADtVLKKLDEQYQKYKFMELNLA |
| P61978 | S284 | Sugiyama | HNRNPK HNRPK | MPPGRGGRPMPPSRRDyDDMsPRRGPPPPPPGRGGRGGsRA |
| P61981 | S38 | Sugiyama | YWHAG | ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS |
| P61981 | Y49 | Sugiyama | YWHAG | NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK |
| P62195 | T109 | Sugiyama | PSMC5 SUG1 | VHPEGKFVVDVDKNIDINDVtPNCRVALRNDsytLHKILPN |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | Y49 | Sugiyama | YWHAE | KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK |
| P62263 | S137 | Sugiyama | RPS14 PRO2640 | RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______ |
| P62263 | T133 | Sugiyama | RPS14 PRO2640 | QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__ |
| P62273 | Y7 | Sugiyama | RPS29 | ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR |
| P62277 | S14 | Sugiyama | RPS13 | _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62736 | T320 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62826 | S150 | Sugiyama | RAN ARA24 OK/SW-cl.81 | KVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARKLIG |
| P62826 | T66 | Sugiyama | RAN ARA24 OK/SW-cl.81 | EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA |
| P62829 | S115 | Sugiyama | RPL23 | FLYFEDNAGVIVNNKGEMKGsAItGPVAKECADLWPRIASN |
| P62829 | T118 | Sugiyama | RPL23 | FEDNAGVIVNNKGEMKGsAItGPVAKECADLWPRIASNAGs |
| P62851 | T69 | Sugiyama | RPS25 | LFDKAtyDKLCKEVPNYKLItPAVVsERLKIRGSLARAALQ |
| P62913 | T44 | Sugiyama | RPL11 | ICVGEsGDRLtRAAKVLEQLtGQtPVFsKARyTVRsFGIRR |
| P62913 | T47 | Sugiyama | RPL11 | GEsGDRLtRAAKVLEQLtGQtPVFsKARyTVRsFGIRRNEK |
| P62942 | S9 | Sugiyama | FKBP1A FKBP1 FKBP12 | ____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG |
| P63104 | T30 | Sugiyama | YWHAZ | AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN |
| P63104 | Y48 | Sugiyama | YWHAZ | sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK |
| P63261 | T106 | Sugiyama | ACTG1 ACTG | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63261 | T318 | Sugiyama | ACTG1 ACTG | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P63267 | T319 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P67809 | Y208 | Sugiyama | YBX1 NSEP1 YB1 | yRRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGE |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68032 | T320 | Sugiyama | ACTC1 ACTC | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68104 | T261 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68133 | T320 | Sugiyama | ACTA1 ACTA | VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68363 | S439 | Sugiyama | TUBA1B | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | Y432 | Sugiyama | TUBA1B | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| P68363 | Y83 | Sugiyama | TUBA1B | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| P78347 | S210 | Sugiyama | GTF2I BAP135 WBSCR6 | EPKKHVGGRVMVtDADRsILsPGGsCGPIKVKTEPTEDSGI |
| P78371 | S143 | Sugiyama | CCT2 99D8.1 CCTB | PQTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIA |
| P78371 | S144 | Sugiyama | CCT2 99D8.1 CCTB | QTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIAG |
| P78371 | T475 | Sugiyama | CCT2 99D8.1 CCTB | GYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGITE |
| P78527 | T2645 | Sugiyama | PRKDC HYRC HYRC1 | LSARWPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstD |
| P83731 | S38 | Sugiyama | RPL24 | GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK |
| P85037 | S420 | Sugiyama | FOXK1 MNF | RGVSCFRtPFGPLssRsAPAsPtHPGLMsPRsGGLQtPECL |
| P85037 | S428 | Sugiyama | FOXK1 MNF | PFGPLssRsAPAsPtHPGLMsPRsGGLQtPECLsREGsPIP |
| Q00613 | S303 | PSP | HSF1 HSTF1 | SIDERPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDt |
| Q00613 | S307 | PSP | HSF1 HSTF1 | RPLSSsPLVRVKEEPPsPPQsPRVEEAsPGRPssVDtLLsP |
| Q00613 | S326 | PSP | HSF1 HSTF1 | QsPRVEEAsPGRPssVDtLLsPtALIDsILREsEPAPAsVT |
| Q01094 | S403 | PSP | E2F1 RBBP3 | LLEHVREDFSGLLPEEFISLsPPHEALDYHFGLEEGEGIRD |
| Q01094 | T433 | PSP | E2F1 RBBP3 | FGLEEGEGIRDLFDCDFGDLtPLDF________________ |
| Q01105 | S161 | Sugiyama | SET | FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK |
| Q01130 | S212 | Sugiyama | SRSF2 SFRS2 | PPPVsKRESKSRSRsKsPPKsPEEEGAVss___________ |
| Q01844 | T422 | Sugiyama | EWSR1 EWS | LDKETGKPKGDATVSyEDPPtAKAAVEWFDGKDFQGSKLKV |
| Q01844 | T79 | SIGNOR|PSP | EWSR1 EWS | ATYGQTAYATSYGQPPTGYttPtAPQAYSQPVQGYGTGAYD |
| Q02156 | S350 | PSP | PRKCE PKCE | PQPAsGssPsEEDRsKsAPtsPCDQEIKELENNIRKALsFD |
| Q02952 | S286 | Sugiyama | AKAP12 AKAP250 | KEEGEEKQEKEPSKsAEsPtsPVtsETGstFKKFFTQGWAG |
| Q02952 | T289 | Sugiyama | AKAP12 AKAP250 | GEEKQEKEPSKsAEsPtsPVtsETGstFKKFFTQGWAGWRK |
| Q04637 | S1231 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | tEDRDRGRDAVKREAALPPVsPLKAALsEEELEKKsKAIIE |
| Q04917 | Y49 | Sugiyama | YWHAH YWHA1 | AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK |
| Q05639 | T261 | Sugiyama | EEF1A2 EEF1AL STN | PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA |
| Q07021 | T163 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | FDGEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALV |
| Q07021 | T165 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD |
| Q07866 | S460 | Sugiyama | KLC1 KLC KNS2 | QKDGTsFGEyGGWyKACKVDsPtVTTtLKNLGALyRRQGKF |
| Q08J23 | S383 | Sugiyama | NSUN2 SAKI TRM4 | QWKVMTKDGQWFTDWDAVPHsRHTQIRPTMFPPKDPEKLQA |
| Q08J23 | S743 | Sugiyama | NSUN2 SAKI TRM4 | AstGQPDNDVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGV |
| Q08J23 | S751 | Sugiyama | NSUN2 SAKI TRM4 | DVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGVHPPR____ |
| Q09472 | S12 | PSP | EP300 P300 | _________MAENVVEPGPPsAKRPKLsSPALsASASDGTD |
| Q09666 | S177 | Sugiyama | AHNAK PM227 | VtAytVDVTGREGAKDIDIssPEFKIKIPRHELtEISNVDV |
| Q09666 | S41 | Sugiyama | AHNAK PM227 | HGLTIAQRDDGVFVQEVtQNsPAARTGVVKEGDQIVGATIy |
| Q09666 | T3716 | Sugiyama | AHNAK PM227 | VEGDLKGPEVDIKGPKVDIDtPDINIEGsEGKFKGPKFKIP |
| Q09666 | T4564 | Sugiyama | AHNAK PM227 | LEGDLKGPKVDVKGPKVGIDtPDIDIHGPEGKLKGPKFKMP |
| Q12888 | T1609 | SIGNOR | TP53BP1 | SLEQGNRLREQYGLGPYEAVtPLtKAADIsLDNLVEGKRKR |
| Q12948 | S241 | SIGNOR | FOXC1 FKHL7 FREAC3 | VRIQDIKtENGtCPsPPQPLsPAAALGsGsAAAVPKIEsPD |
| Q12948 | S272 | SIGNOR | FOXC1 FKHL7 FREAC3 | AAVPKIEsPDsSsSSLSsGssPPGSLPSARPLSLDGADSAP |
| Q13200 | S16 | Sugiyama | PSMD2 TRAP2 | _____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA |
| Q13283 | S231 | Sugiyama | G3BP1 G3BP | QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW |
| Q13283 | S232 | Sugiyama | G3BP1 G3BP | EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA |
| Q13283 | T241 | Sugiyama | G3BP1 G3BP | ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP |
| Q13404 | S146 | Sugiyama | UBE2V1 CROC1 UBE2V UEV1 P/OKcl.19 | RLMMSKENMKLPQPPEGQCysN___________________ |
| Q13428 | T1014 | Sugiyama | TCOF1 | ARssssEsEDEDVIPAtQCLtPGIRTNVVTMPTAHPRIAPK |
| Q13501 | S272 | Sugiyama | SQSTM1 ORCA OSIL | GIEVDIDVEHGGKRsRLtPVsPEssstEEKsssQPssCCsD |
| Q13509 | S75 | Sugiyama | TUBB3 TUBB4 | SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS |
| Q13509 | T72 | Sugiyama | TUBB3 TUBB4 | NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF |
| Q13885 | S75 | Sugiyama | TUBB2A TUBB2 | AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q13885 | T72 | Sugiyama | TUBB2A TUBB2 | NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| Q14103 | T193 | Sugiyama | HNRNPD AUF1 HNRPD | KAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVESIEL |
| Q14203 | T108 | Sugiyama | DCTN1 | FVRQSQIQVFEDGADttsPEtPDSSASKVLKREGTDTTAKT |
| Q14247 | S282 | Sugiyama | CTTN EMS1 | QKDyKTGFGGKFGVQsERQDsAAVGFDyKEKLAKHEsQQDy |
| Q14247 | S332 | Sugiyama | CTTN EMS1 | VQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIRA |
| Q14247 | S405 | Sugiyama | CTTN EMS1 | EEARRKLEEQARAKtQtPPVsPAPQPtEERLPssPVyEDAA |
| Q14247 | S418 | Sugiyama | CTTN EMS1 | KtQtPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVs |
| Q14498 | S334 | Sugiyama | RBM39 HCC1 RNPC2 | FELAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtT |
| Q14568 | S164 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGT |
| Q14568 | S165 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14847 | T104 | Sugiyama | LASP1 MLN50 | VRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsNIKyHE |
| Q14934 | S168 | SIGNOR | NFATC4 NFAT3 | PPEGFGGYREAGGQGGGAFFsPsPGSSSLSSWSFFSDASDE |
| Q14934 | S170 | SIGNOR | NFATC4 NFAT3 | EGFGGYREAGGQGGGAFFsPsPGSSSLSSWSFFSDASDEAA |
| Q14974 | S12 | Sugiyama | KPNB1 NTF97 | _________MELITILEKtVsPDRLELEAAQKFLERAAVEN |
| Q14980 | S1757 | Sugiyama | NUMA1 NMP22 NUMA | ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP |
| Q15084 | T166 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | YSSGKQGRSDsSSKKDVIELtDDsFDKNVLDSEDVWMVEFY |
| Q15181 | S250 | Sugiyama | PPA1 IOPPP PP | LVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDALPPPC |
| Q15181 | T246 | Sugiyama | PPA1 IOPPP PP | HWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDAL |
| Q15293 | T76 | Sugiyama | RCN1 RCN | FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD |
| Q15642 | T302 | Sugiyama | TRIP10 CIP4 STOT STP | VEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTKRWP |
| Q15672 | S68 | SIGNOR | TWIST1 BHLHA38 TWIST | GGAGPGGAAGGGVGGGDEPGsPAQGKRGKKSAGCGGGGGAG |
| Q15759 | S143 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | SDEHVQFLVYQLLRGLKYIHsAGIIHRDLKPSNVAVNEDCE |
| Q15759 | S243 | SIGNOR | MAPK11 PRKM11 SAPK2 SAPK2B | FPGSDYIDQLKRIMEVVGtPsPEVLAKISSEHARTYIQsLP |
| Q15759 | S261 | SIGNOR|PSP | MAPK11 PRKM11 SAPK2 SAPK2B | tPsPEVLAKISSEHARTYIQsLPPMPQKDLSsIFRGANPLA |
| Q15759 | S293 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | IFRGANPLAIDLLGRMLVLDsDQRVSAAEALAHAYFSQYHD |
| Q15759 | S32 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | ELNKTVWEVPQRLQGLRPVGsGAyGsVCsAyDARLRQKVAV |
| Q15759 | S37 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | VWEVPQRLQGLRPVGsGAyGsVCsAyDARLRQKVAVKKLSR |
| Q15759 | S40 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | VPQRLQGLRPVGsGAyGsVCsAyDARLRQKVAVKKLSRPFQ |
| Q15759 | T180 | SIGNOR|Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | EDCELRILDFGLARQADEEMtGyVAtRWYRAPEIMLNWMHY |
| Q15759 | T185 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | RILDFGLARQADEEMtGyVAtRWYRAPEIMLNWMHYNQTVD |
| Q15759 | T241 | PSP | MAPK11 PRKM11 SAPK2 SAPK2B | ALFPGSDYIDQLKRIMEVVGtPsPEVLAKISSEHARTYIQs |
| Q15759 | Y182 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | CELRILDFGLARQADEEMtGyVAtRWYRAPEIMLNWMHYNQ |
| Q15759 | Y35 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | KTVWEVPQRLQGLRPVGsGAyGsVCsAyDARLRQKVAVKKL |
| Q15759 | Y42 | Sugiyama | MAPK11 PRKM11 SAPK2 SAPK2B | QRLQGLRPVGsGAyGsVCsAyDARLRQKVAVKKLSRPFQSL |
| Q15785 | S44 | Sugiyama | TOMM34 URCC3 | QyAEASALyGRALRVLQAQGssDPEEEsVLysNRAACHLKD |
| Q16204 | S240 | Sugiyama | CCDC6 D10S170 TST1 | RMDKLEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMR |
| Q16204 | S244 | Sugiyama | CCDC6 D10S170 TST1 | LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF |
| Q16543 | T370 | Sugiyama | CDC37 CDC37A | EAKEGEEAGPGDPLLEAVPKtGDEKDVsV____________ |
| Q16630 | T157 | Sugiyama | CPSF6 CFIM68 | SKKLMDLLPKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQS |
| Q16643 | T346 | Sugiyama | DBN1 D0S117E | RRMAPtPIPtRsPsDsstAstPVAEQIERALDEVTsSQPPP |
| Q53EL6 | S94 | Sugiyama | PDCD4 H731 | GDsVsDsGsDALRSGLtVPtsPKGRLLDRRSRSGKGRGLPK |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF8 | Y260 | Sugiyama | HSP90AB2P HSP90BB | VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW |
| Q58FF8 | Y261 | Sugiyama | HSP90AB2P HSP90BB | RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK |
| Q5JSH3 | T94 | Sugiyama | WDR44 RPH11 | VLQLEDDsLDSKGKELsDQAtAsPIVARTDLSNIPGLLAID |
| Q5SW79 | T1533 | Sugiyama | CEP170 FAM68A KAB KIAA0470 | LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA |
| Q5T4S7 | S178 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | AKLPQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLT |
| Q5T4S7 | S181 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | PQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLTSVF |
| Q5VT52 | S965 | Sugiyama | RPRD2 KIAA0460 HSPC099 | NsLsQsttGHLSLPQKQyPDsPHPVPHRsLFsPQNtLAAPT |
| Q5VTE0 | T261 | Sugiyama | EEF1A1P5 EEF1AL3 | PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA |
| Q6PKG0 | S774 | Sugiyama | LARP1 KIAA0731 LARP | LFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtPQLKDS |
| Q6PKG0 | T769 | Sugiyama | LARP1 KIAA0731 LARP | ALANKLFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtP |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71U36 | S439 | Sugiyama | TUBA1A TUBA3 | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | Y432 | Sugiyama | TUBA1A TUBA3 | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| Q71U36 | Y83 | Sugiyama | TUBA1A TUBA3 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q7L2J0 | S216 | Sugiyama | MEPCE BCDIN3 | NLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDIt |
| Q7L2J0 | T213 | Sugiyama | MEPCE BCDIN3 | DPLNLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPK |
| Q7Z417 | S692 | Sugiyama | NUFIP2 KIAA1321 PIG1 | IWNLQKQDPKRIItyNEAMDsPDQ_________________ |
| Q86V81 | T148 | Sugiyama | ALYREF ALY BEF THOC4 | EFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQYNG |
| Q86YP4 | S100 | Sugiyama | GATAD2A | DGPVDMRTSHSDMKSERRPPsPDVIVLsDNEQPssPRVNGL |
| Q86YP4 | S114 | Sugiyama | GATAD2A | SERRPPsPDVIVLsDNEQPssPRVNGLttVALKETSTEALM |
| Q8IW41 | T182 | SIGNOR|ELM|iPTMNet|EPSD|PSP | MAPKAPK5 PRAK | DAPVKLCDFGFAKIDQGDLMtPQFtPyYVAPQVLEAQRRHQ |
| Q8IWW6 | S240 | Sugiyama | ARHGAP12 | SSSsTEQIRAttPPNQGRPDsPVyANLQELKISQSALPPLP |
| Q8IWW6 | T231 | Sugiyama | ARHGAP12 | QDSEsGDELSSSsTEQIRAttPPNQGRPDsPVyANLQELKI |
| Q8IZ21 | S118 | Sugiyama | PHACTR4 PRO2963 | PSDAMLKNGHTTPIGNARsssPVQVEEEPVRLAsLRKAIPE |
| Q8N122 | S771 | SIGNOR|PSP | RPTOR KIAA1303 RAPTOR | AVAFSPGNLSTSSSASSTLGsPENEEHILSFETIDKMRRAs |
| Q8N122 | S863 | SIGNOR|PSP | RPTOR KIAA1303 RAPTOR | VNARPQRVLDtssLtQsAPAsPtNKGVHIHQAGGsPPAsst |
| Q8N1F7 | S430 | Sugiyama | NUP93 KIAA0095 | TEDYLWLKLNQVCFDDDGTssPQDRLTLsQFQKQLLEDYGE |
| Q8N556 | S264 | Sugiyama | AFAP1 AFAP | IKEAYSGCSGPVDSECPPPPssPVHKAELEKKLssERPssD |
| Q8NBJ5 | S612 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | QKMREQQALSREAKNsDVLQsPLDsAARDEL__________ |
| Q8NBJ5 | S616 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | EQQALSREAKNsDVLQsPLDsAARDEL______________ |
| Q8NBJ7 | S264 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | AAEQDMRVLRGAsWIDtADGsANHRARVttRMGNtPDsAsD |
| Q8NBJ7 | S281 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | ADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL |
| Q8NBJ7 | T260 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | SPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMGNtPD |
| Q8NBJ7 | T278 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | IDtADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPP |
| Q8ND56 | S300 | Sugiyama | LSM14A C19orf13 FAM61A RAP55 RAP55A | GRFGIRRDGPMKFEKDFDFEsANAQFNKEEIDREFHNKLKL |
| Q8NFI4 | S181 | Sugiyama | ST13P5 FAM10A5 | LQKPNAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| Q8TC07 | S675 | Sugiyama | TBC1D15 | TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____ |
| Q8WWM7 | S111 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | PGAAAIGsARGQstGKGPPQsPVFEGVyNNSRMLHFLTAVV |
| Q8WXI9 | S135 | Sugiyama | GATAD2B KIAA1150 | ERGRLtPsPDIIVLsDNEAssPRsSsRMEERLKAANLEMFK |
| Q8WXI9 | S486 | Sugiyama | GATAD2B KIAA1150 | VKALQQEQEIEQRLQQQAALsPttAPAVssVsKQETIMRHH |
| Q8WXI9 | T120 | Sugiyama | GATAD2B KIAA1150 | INDEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSs |
| Q92530 | S153 | Sugiyama | PSMF1 | RIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIPP |
| Q92530 | T162 | Sugiyama | PSMF1 | IHEQWEKANVssPHREFPPAtAREVDPLRIPPHHPHTSRQP |
| Q92609 | S539 | Sugiyama | TBC1D5 KIAA0210 | KsEsMPVQLNKGLSSKNIsssPsVEsLPGGREFtGsPPssA |
| Q92688 | S104 | Sugiyama | ANP32B APRIL PHAPI2 | AEKLPNLTHLNLsGNKLKDIstLEPLKKLECLKsLDLFNCE |
| Q92945 | S181 | Sugiyama | KHSRP FUBP2 | GRGGEQINKIQQDSGCKVQIsPDsGGLPERsVsLtGAPEsV |
| Q92945 | T100 | Sugiyama | KHSRP FUBP2 | RARQIAAKIGGDAAttVNNstPDFGFGGQKRQLEDGDQPEs |
| Q92945 | T95 | Sugiyama | KHSRP FUBP2 | ADAVQRARQIAAKIGGDAAttVNNstPDFGFGGQKRQLEDG |
| Q92993 | T158 | PSP | KAT5 HTATIP TIP60 | SCLQPNHRSTKRKVEVVsPAtPVPSETAPASVFPQNGAARR |
| Q96AE4 | S140 | Sugiyama | FUBP1 | GEQISRIQQESGCKIQIAPDsGGLPERsCMLtGtPESVQSA |
| Q96B36 | S212 | Sugiyama | AKT1S1 PRAS40 | GFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAED |
| Q96C19 | S74 | Sugiyama | EFHD2 SWS1 | ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI |
| Q96CT7 | S207 | Sugiyama | CCDC124 | ENPNMRLsQLKQLLKKEWLRsPDNPMNQRAVPFNAPK____ |
| Q96D15 | T72 | Sugiyama | RCN3 UNQ239/PRO272 | FQYDHEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGD |
| Q96EN8 | S530 | Sugiyama | MOCOS | APSADSQADVIPAVMGRRsLsPQEDALTGSRVWNNSSTVNA |
| Q96L14 | T242 | Sugiyama | CEP170P1 CEP170L KIAA0470L | LPsPPKQKssPVNNHHsPGQtPtLGQPEARALHPAAVSAAA |
| Q96L92 | S51 | PSP | SNX27 KIAA0488 My014 | AGNGGGGGGGPRVVRIVKsEsGYGFNVRGQVsEGGQLRSIN |
| Q96MH2 | S76 | Sugiyama | HEXIM2 L3 | EDLAGAVGGLGWNsRsPRtQsPGGCsAEAVLARKKHRRRPS |
| Q96S59 | T163 | Sugiyama | RANBP9 RANBPM | QEKELQRRLKRLYPAVDEQEtPLPRSWsPKDKFsYIGLsQN |
| Q99460 | T830 | Sugiyama | PSMD1 | TFAYPAPLEVPKEKEKEKVStAVLsItAKAKKKEKEKEKKE |
| Q99460 | T836 | Sugiyama | PSMD1 | PLEVPKEKEKEKVStAVLsItAKAKKKEKEKEKKEEEKMEV |
| Q99497 | T154 | Sugiyama | PARK7 | MNGGHytysENRVEKDGLILtSRGPGTSFEFALAIVEALNG |
| Q9BQE3 | S439 | Sugiyama | TUBA1C TUBA6 | SEAREDMAALEKDyEEVGADsADGEDEGEEy__________ |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | Y83 | Sugiyama | TUBA1C TUBA6 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q9BVA1 | S75 | Sugiyama | TUBB2B | tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q9BVA1 | T72 | Sugiyama | TUBB2B | NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9C000 | S107 | PSP | NLRP1 CARD7 DEFCAP KIAA0926 NAC NALP1 | QEGAGHSPSFPYSPSEPHLGsPSQPTSTAVLMPWIHELPAG |
| Q9C0C2 | S1029 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LGEGsRDAGRPGERGsGGLFsPstAHVPDGALGQRDQssWQ |
| Q9C0C2 | S1103 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ |
| Q9C0C2 | S435 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | DAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAALPQGQG |
| Q9C0C2 | S601 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | LPLQQAEERyEsQEPLAGQEsPLPLATREAALPILEPVLGQ |
| Q9C0C2 | S717 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | GGARRGAGAELKDtQsPstCsEGLLGWsQKDLQSEFGITGD |
| Q9C0C2 | T1032 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | GsRDAGRPGERGsGGLFsPstAHVPDGALGQRDQssWQNsD |
| Q9H078 | S663 | Sugiyama | CLPB SKD3 | LPGGCTLRITVEDSDKQLLKsPELPsPQAEKRLPKLRLEII |
| Q9H078 | S668 | Sugiyama | CLPB SKD3 | TLRITVEDSDKQLLKsPELPsPQAEKRLPKLRLEIIDKDSK |
| Q9H211 | S391 | SIGNOR | CDT1 | IsPRMEKALsQLALRsAAPssPGsPRPALPAtPPAtPPAAs |
| Q9H211 | S491 | SIGNOR | CDT1 | PALSMEVACARMVGSCCTIMsPGEMEKHLLLLSELLPDWLS |
| Q9H2U2 | S317 | Sugiyama | PPA2 HSPC124 | DSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK___ |
| Q9H4A4 | S19 | Sugiyama | RNPEP APB | __MAsGEHsPGsGAARRPLHsAQAVDVAsAsNFRAFELLHL |
| Q9H4A4 | S27 | Sugiyama | RNPEP APB | sPGsGAARRPLHsAQAVDVAsAsNFRAFELLHLHLDLRAEF |
| Q9H4A4 | S29 | Sugiyama | RNPEP APB | GsGAARRPLHsAQAVDVAsAsNFRAFELLHLHLDLRAEFGP |
| Q9H6F5 | S80 | Sugiyama | CCDC86 CYCLON | ERPPKtsPGsPRLQQGAGLEsPQGQPEPGAAsPQRQQDLHL |
| Q9H8Y8 | S436 | Sugiyama | GORASP2 GOLPH6 | PPtAKAPttVEDRVGDstPVsEKPVsAAVDANAsEsP____ |
| Q9H8Y8 | S451 | Sugiyama | GORASP2 GOLPH6 | DstPVsEKPVsAAVDANAsEsP___________________ |
| Q9HAP6 | S115 | Sugiyama | LIN7B MALS2 VELI2 UNQ3116/PRO10200 | ELPKTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLK |
| Q9HCN8 | T70 | Sugiyama | SDF2L1 UNQ1941/PRO4424 | RVRLHSHDIKYGSGSGQQSVtGVEAsDDANSyWRIRGGSEG |
| Q9NQ39 | S157 | Sugiyama | RPS10P5 RPS10L | TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_ |
| Q9NRR4 | S300 | SIGNOR | DROSHA RN3 RNASE3L RNASEN | SYERSRERERERHRHRDNRRsPsLERSYKKEYKRSGRSYGL |
| Q9NUP9 | S115 | Sugiyama | LIN7C MALS3 VELI3 | ELPKTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLK |
| Q9NYB0 | S203 | Sugiyama | TERF2IP DRIP5 RAP1 PP8000 | RYLKHLRGQEHKyLLGDAPVsPssQKLKRKAEEDPEAADsG |
| Q9NZB2 | T991 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | PLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKNQ |
| Q9UBK2 | S266 | ELM | PPARGC1A LEM6 PGC1 PGC1A PPARGC1 | SQSQHLQAKPTTLSLPLtPEsPNDPKGsPFENKTIERTLSV |
| Q9UBK2 | T263 | ELM | PPARGC1A LEM6 PGC1 PGC1A PPARGC1 | HTQSQSQHLQAKPTTLSLPLtPEsPNDPKGsPFENKTIERT |
| Q9UBK2 | T299 | ELM | PPARGC1A LEM6 PGC1 PGC1A PPARGC1 | TIERTLSVELSGTAGLTPPTtPPHKANQDNPFRAsPKLKSS |
| Q9UGV2 | S361 | Sugiyama | NDRG3 | sPFsRsVtsNQsDGtQESCEsPDVLDRHQTMEVsC______ |
| Q9UKX7 | S221 | Sugiyama | NUP50 NPAP60L PRO1146 | HGNsGRNsESEsNKVAAEtQsPsLFGstKLQQEStFLFHGN |
| Q9UNX3 | T8 | Sugiyama | RPL26L1 RPL26P1 | _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK |
| Q9UQ35 | S1318 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | VPsMASSWGGPHFsPEHKELsNsPLRENsFGsPLEFRNsGP |
| Q9UQ35 | S1320 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sMASSWGGPHFsPEHKELsNsPLRENsFGsPLEFRNsGPLG |
| Q9UQ35 | S1329 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | HFsPEHKELsNsPLRENsFGsPLEFRNsGPLGTEMNtGFss |
| Q9Y266 | S139 | Sugiyama | NUDC | IDQKKDAENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKL |
| Q9Y2B0 | S63 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE |
| Q9Y2V2 | S41 | Sugiyama | CARHSP1 | LDtPRsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGP |
| Q9Y2W2 | S237 | Sugiyama | WBP11 NPWBP SIPP1 SNP70 | RKVGFALDLPPRRRDEDMLysPELAQRGHDDDVSSTSEDDG |
| Q9Y3F4 | S228 | Sugiyama | STRAP MAWD UNRIP | FHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLy |
| Q9Y3F4 | T225 | Sugiyama | STRAP MAWD UNRIP | SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF |
| Q9Y4E8 | S225 | Sugiyama | USP15 KIAA0529 | QGQVLVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPss |
| Q9Y4E8 | S229 | Sugiyama | USP15 KIAA0529 | LVIEQKNEDGtWPRGPstPKsPGAsNFstLPKIsPssLsNN |
| Q9Y4P8 | S413 | Sugiyama | WIPI2 CGI-50 | CPLVTQTYGAAAGKGTYVPssPtRLAYTDDLGAVGGACLED |
| Q9Y4P8 | T415 | Sugiyama | WIPI2 CGI-50 | LVTQTYGAAAGKGTYVPssPtRLAYTDDLGAVGGACLEDEA |
| Q9Y5M8 | S257 | Sugiyama | SRPRB PSEC0230 | LPLKVEFLECSAKGGRGDVGsADIQDLEKWLAKIA______ |
| Q9Y6G9 | S516 | Sugiyama | DYNC1LI1 DNCLI1 | HAELDRITRKPVtVsPttPtsPtEGEAs_____________ |
| Q9Y6G9 | T515 | Sugiyama | DYNC1LI1 DNCLI1 | VHAELDRITRKPVtVsPttPtsPtEGEAs____________ |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Chromatin organization | R-HSA-4839726 | 0.000004 | 5.390 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 0.000014 | 4.847 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 0.000014 | 4.847 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 0.000015 | 4.813 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 0.000031 | 4.515 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 0.000054 | 4.264 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 0.000075 | 4.127 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 0.000083 | 4.079 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 0.000113 | 3.949 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 0.000159 | 3.798 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 0.000157 | 3.805 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 0.000195 | 3.709 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 0.000195 | 3.710 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 0.000268 | 3.572 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 0.000303 | 3.518 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 0.000399 | 3.399 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 0.000404 | 3.394 | 1 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 0.000597 | 3.224 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 0.000768 | 3.115 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 0.000795 | 3.099 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 0.000642 | 3.193 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 0.000745 | 3.128 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 0.000752 | 3.124 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 0.000807 | 3.093 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 0.000807 | 3.093 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 0.000807 | 3.093 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 0.000807 | 3.093 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 0.000785 | 3.105 | 1 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 0.000807 | 3.093 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 0.000904 | 3.044 | 1 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 0.001156 | 2.937 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 0.001219 | 2.914 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 0.001421 | 2.847 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 0.001366 | 2.865 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 0.001440 | 2.842 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 0.001491 | 2.827 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 0.001658 | 2.781 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 0.001761 | 2.754 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 0.001849 | 2.733 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 0.001984 | 2.702 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 0.002194 | 2.659 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 0.002176 | 2.662 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 0.002212 | 2.655 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 0.002360 | 2.627 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 0.002583 | 2.588 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 0.002583 | 2.588 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 0.002583 | 2.588 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 0.002970 | 2.527 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 0.002970 | 2.527 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 0.003221 | 2.492 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 0.003407 | 2.468 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 0.003318 | 2.479 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 0.003983 | 2.400 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 0.004485 | 2.348 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 0.004656 | 2.332 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 0.004677 | 2.330 | 1 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 0.004856 | 2.314 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 0.005474 | 2.262 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 0.005238 | 2.281 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 0.005238 | 2.281 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 0.005238 | 2.281 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 0.005359 | 2.271 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 0.005547 | 2.256 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 0.005650 | 2.248 | 1 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 0.005811 | 2.236 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 0.007448 | 2.128 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 0.007507 | 2.125 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 0.008394 | 2.076 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 0.009191 | 2.037 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 0.009147 | 2.039 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 0.009421 | 2.026 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 0.009975 | 2.001 | 1 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 0.010451 | 1.981 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 0.010997 | 1.959 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 0.011670 | 1.933 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 0.012028 | 1.920 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 0.012719 | 1.896 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 0.012929 | 1.888 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 0.014487 | 1.839 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 0.014934 | 1.826 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 0.015576 | 1.808 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 0.016373 | 1.786 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 0.018591 | 1.731 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 0.018717 | 1.728 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 0.018717 | 1.728 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 0.018377 | 1.736 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 0.020715 | 1.684 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 0.021040 | 1.677 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 0.022374 | 1.650 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 0.023228 | 1.634 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 0.023156 | 1.635 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 0.023228 | 1.634 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 0.022374 | 1.650 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 0.023274 | 1.633 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 0.025368 | 1.596 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 0.026747 | 1.573 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 0.027079 | 1.567 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 0.029815 | 1.526 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 0.029815 | 1.526 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 0.028536 | 1.545 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 0.028536 | 1.545 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 0.028916 | 1.539 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 0.028916 | 1.539 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 0.031909 | 1.496 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 0.032019 | 1.495 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 0.032998 | 1.482 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 0.033157 | 1.479 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 0.036690 | 1.435 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 0.033935 | 1.469 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 0.036377 | 1.439 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 0.035951 | 1.444 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 0.034375 | 1.464 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 0.037144 | 1.430 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 0.037144 | 1.430 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 0.037144 | 1.430 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 0.037478 | 1.426 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 0.038416 | 1.415 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 0.038635 | 1.413 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 0.039290 | 1.406 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 0.040408 | 1.394 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 0.045664 | 1.340 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 0.042691 | 1.370 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 0.045749 | 1.340 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 0.047745 | 1.321 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 0.047745 | 1.321 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 0.047745 | 1.321 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 0.048610 | 1.313 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 0.048610 | 1.313 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 0.048635 | 1.313 | 0 | 0 |
| IRS activation | R-HSA-74713 | 0.048942 | 1.310 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 0.049098 | 1.309 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 0.050689 | 1.295 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 0.057191 | 1.243 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 0.057191 | 1.243 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 0.057191 | 1.243 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 0.055754 | 1.254 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 0.057191 | 1.243 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 0.052121 | 1.283 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 0.055250 | 1.258 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 0.057770 | 1.238 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 0.059971 | 1.222 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 0.061892 | 1.208 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 0.061892 | 1.208 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 0.061892 | 1.208 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 0.061892 | 1.208 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 0.062213 | 1.206 | 1 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 0.062619 | 1.203 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 0.063281 | 1.199 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 0.063281 | 1.199 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 0.095488 | 1.020 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 0.095488 | 1.020 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 0.139761 | 0.855 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 0.139761 | 0.855 | 0 | 0 |
| Defective MMADHC causes MMAHCD | R-HSA-3359473 | 0.139761 | 0.855 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 0.181869 | 0.740 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 0.181869 | 0.740 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 0.181869 | 0.740 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 0.181869 | 0.740 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 0.181869 | 0.740 | 0 | 0 |
| Glycogen storage disease type IV (GBE1) | R-HSA-3878781 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 0.181869 | 0.740 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 0.181869 | 0.740 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 0.181869 | 0.740 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 0.181869 | 0.740 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 0.075853 | 1.120 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 0.075853 | 1.120 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 0.090694 | 1.042 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 0.090694 | 1.042 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 0.221918 | 0.654 | 0 | 0 |
| Defective MMACHC causes MAHCC | R-HSA-3359474 | 0.221918 | 0.654 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 0.221918 | 0.654 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 0.221918 | 0.654 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 0.221918 | 0.654 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 0.122552 | 0.912 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 0.260010 | 0.585 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 0.260010 | 0.585 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 0.260010 | 0.585 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 0.260010 | 0.585 | 0 | 0 |
| Signaling by LRP5 mutants | R-HSA-5339717 | 0.260010 | 0.585 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 0.139358 | 0.856 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 0.156622 | 0.805 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 0.296238 | 0.528 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 0.296238 | 0.528 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 0.296238 | 0.528 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 0.296238 | 0.528 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 0.296238 | 0.528 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 0.296238 | 0.528 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 0.296238 | 0.528 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 0.174259 | 0.759 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 0.174259 | 0.759 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 0.192191 | 0.716 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 0.192191 | 0.716 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 0.192191 | 0.716 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 0.192191 | 0.716 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 0.192191 | 0.716 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 0.330695 | 0.481 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 0.330695 | 0.481 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 0.330695 | 0.481 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 0.330695 | 0.481 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 0.330695 | 0.481 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 0.330695 | 0.481 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 0.330695 | 0.481 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 0.210347 | 0.677 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 0.210347 | 0.677 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 0.210347 | 0.677 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 0.109519 | 0.961 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 0.228664 | 0.641 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 0.228664 | 0.641 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 0.363467 | 0.440 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 0.363467 | 0.440 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 0.363467 | 0.440 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 0.363467 | 0.440 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 0.363467 | 0.440 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 0.363467 | 0.440 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 0.363467 | 0.440 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 0.117744 | 0.929 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 0.117744 | 0.929 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 0.167576 | 0.776 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 0.247080 | 0.607 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 0.247080 | 0.607 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 0.247080 | 0.607 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 0.134961 | 0.870 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 0.134961 | 0.870 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 0.103063 | 0.987 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 0.109696 | 0.960 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 0.143932 | 0.842 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 0.394636 | 0.404 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 0.394636 | 0.404 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 0.394636 | 0.404 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 0.394636 | 0.404 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 0.394636 | 0.404 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 0.424281 | 0.372 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 0.424281 | 0.372 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 0.424281 | 0.372 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 0.424281 | 0.372 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 0.424281 | 0.372 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 0.424281 | 0.372 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 0.424281 | 0.372 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 0.424281 | 0.372 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 0.130555 | 0.884 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 0.202108 | 0.694 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 0.320753 | 0.494 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 0.257609 | 0.589 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 0.104879 | 0.979 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 0.104879 | 0.979 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 0.212417 | 0.673 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 0.212417 | 0.673 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 0.338962 | 0.470 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 0.338962 | 0.470 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 0.338962 | 0.470 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 0.452476 | 0.344 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 0.452476 | 0.344 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 0.452476 | 0.344 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 0.233452 | 0.632 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 0.233452 | 0.632 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 0.233452 | 0.632 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 0.357019 | 0.447 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 0.164047 | 0.785 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 0.254961 | 0.594 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 0.193524 | 0.713 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 0.479291 | 0.319 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 0.479291 | 0.319 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 0.479291 | 0.319 | 1 | 1 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 0.276850 | 0.558 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 0.224629 | 0.649 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 0.204069 | 0.690 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 0.338837 | 0.470 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 0.409998 | 0.387 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 0.409998 | 0.387 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 0.409998 | 0.387 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 0.409998 | 0.387 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 0.504795 | 0.297 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 0.365956 | 0.437 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 0.299560 | 0.524 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 0.460747 | 0.337 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 0.493129 | 0.307 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 0.493129 | 0.307 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 0.493129 | 0.307 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 0.249794 | 0.602 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 0.508852 | 0.293 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 0.508852 | 0.293 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 0.508852 | 0.293 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 0.508852 | 0.293 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 0.477072 | 0.321 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 0.477072 | 0.321 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 0.508919 | 0.293 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 0.502085 | 0.299 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 0.502907 | 0.299 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 0.334685 | 0.475 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 0.218005 | 0.662 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 0.082380 | 1.084 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 0.143819 | 0.842 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 0.143819 | 0.842 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 0.383601 | 0.416 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 0.218005 | 0.662 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 0.100245 | 0.999 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 0.100245 | 0.999 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 0.221127 | 0.655 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 0.119874 | 0.921 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 0.515224 | 0.288 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 0.374893 | 0.426 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 0.094153 | 1.026 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 0.079404 | 1.100 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 0.192191 | 0.716 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 0.109519 | 0.961 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 0.129355 | 0.888 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 0.394636 | 0.404 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 0.111635 | 0.952 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 0.419502 | 0.377 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 0.247080 | 0.607 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 0.394636 | 0.404 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 0.090323 | 1.044 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 0.103063 | 0.987 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 0.155555 | 0.808 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 0.284006 | 0.547 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 0.139358 | 0.856 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 0.284006 | 0.547 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 0.298066 | 0.526 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 0.392561 | 0.406 | 1 | 1 |
| HDACs deacetylate histones | R-HSA-3214815 | 0.388892 | 0.410 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 0.392561 | 0.406 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 0.409998 | 0.387 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 0.460747 | 0.337 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 0.508852 | 0.293 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 0.450946 | 0.346 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 0.247080 | 0.607 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 0.126351 | 0.898 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 0.106297 | 0.973 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 0.260010 | 0.585 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 0.090323 | 1.044 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 0.210347 | 0.677 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 0.247080 | 0.607 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 0.424281 | 0.372 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 0.409998 | 0.387 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 0.301071 | 0.521 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 0.433452 | 0.363 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 0.192191 | 0.716 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 0.388892 | 0.410 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 0.493129 | 0.307 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 0.393580 | 0.405 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 0.257609 | 0.589 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 0.271027 | 0.567 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 0.352413 | 0.453 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 0.354287 | 0.451 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 0.184952 | 0.733 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 0.174259 | 0.759 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 0.073074 | 1.136 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 0.228664 | 0.641 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 0.394636 | 0.404 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 0.122414 | 0.912 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 0.352413 | 0.453 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 0.504795 | 0.297 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 0.185948 | 0.731 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 0.258442 | 0.588 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 0.477091 | 0.321 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 0.471461 | 0.327 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 0.519340 | 0.285 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 0.345130 | 0.462 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 0.504795 | 0.297 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 0.079404 | 1.100 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 0.260010 | 0.585 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 0.260010 | 0.585 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 0.071818 | 1.144 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 0.174259 | 0.759 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 0.079404 | 1.100 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 0.167576 | 0.776 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 0.157210 | 0.804 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 0.452476 | 0.344 | 1 | 1 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 0.159454 | 0.797 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 0.504795 | 0.297 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 0.418462 | 0.378 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 0.191954 | 0.717 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 0.137003 | 0.863 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 0.075853 | 1.120 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 0.212417 | 0.673 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 0.212417 | 0.673 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 0.198569 | 0.702 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 0.445723 | 0.351 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 0.360023 | 0.444 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 0.452476 | 0.344 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 0.357019 | 0.447 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 0.286847 | 0.542 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 0.241290 | 0.617 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 0.157210 | 0.804 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 0.150334 | 0.823 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 0.493129 | 0.307 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 0.134961 | 0.870 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 0.103097 | 0.987 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 0.139761 | 0.855 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 0.139761 | 0.855 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 0.181869 | 0.740 | 0 | 0 |
| TGFBR3 regulates activin signaling | R-HSA-9839406 | 0.181869 | 0.740 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 0.221918 | 0.654 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 0.221918 | 0.654 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 0.260010 | 0.585 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 0.139358 | 0.856 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 0.090323 | 1.044 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 0.174259 | 0.759 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 0.121306 | 0.916 | 0 | 0 |
| Sensory perception of salty taste | R-HSA-9730628 | 0.330695 | 0.481 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 0.330695 | 0.481 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 0.210347 | 0.677 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 0.228664 | 0.641 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 0.363467 | 0.440 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 0.247080 | 0.607 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 0.181967 | 0.740 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 0.302422 | 0.519 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 0.302422 | 0.519 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 0.320753 | 0.494 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 0.082622 | 1.083 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 0.479291 | 0.319 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 0.276850 | 0.558 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 0.267223 | 0.573 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 0.504795 | 0.297 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 0.205857 | 0.686 | 1 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 0.452018 | 0.345 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 0.430104 | 0.366 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 0.244153 | 0.612 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 0.477091 | 0.321 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 0.164220 | 0.785 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 0.128109 | 0.892 | 1 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 0.445723 | 0.351 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 0.471461 | 0.327 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 0.230152 | 0.638 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 0.444108 | 0.353 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 0.247080 | 0.607 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 0.338962 | 0.470 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 0.444108 | 0.353 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 0.112124 | 0.950 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 0.311646 | 0.506 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 0.267607 | 0.573 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 0.245366 | 0.610 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 0.496642 | 0.304 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 0.404809 | 0.393 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 0.357838 | 0.446 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 0.140123 | 0.853 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 0.335670 | 0.474 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 0.072614 | 1.139 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 0.357019 | 0.447 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 0.338837 | 0.470 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 0.340670 | 0.468 | 1 | 1 |
| FLT3 signaling in disease | R-HSA-9682385 | 0.172159 | 0.764 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 0.144259 | 0.841 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 0.071818 | 1.144 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 0.179856 | 0.745 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 0.424281 | 0.372 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 0.357019 | 0.447 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 0.265864 | 0.575 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 0.265864 | 0.575 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 0.267223 | 0.573 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 0.452018 | 0.345 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 0.266885 | 0.574 | 1 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 0.083225 | 1.080 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 0.106297 | 0.973 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 0.192191 | 0.716 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 0.192191 | 0.716 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 0.192191 | 0.716 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 0.192191 | 0.716 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 0.330695 | 0.481 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 0.143932 | 0.842 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 0.394636 | 0.404 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 0.302422 | 0.519 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 0.338962 | 0.470 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 0.452476 | 0.344 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 0.479291 | 0.319 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 0.444108 | 0.353 | 0 | 0 |
| S Phase | R-HSA-69242 | 0.324544 | 0.489 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 0.065643 | 1.183 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 0.068643 | 1.163 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 0.080839 | 1.092 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 0.080839 | 1.092 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 0.093886 | 1.027 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 0.257609 | 0.589 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 0.460747 | 0.337 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 0.271027 | 0.567 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 0.445522 | 0.351 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 0.205095 | 0.688 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 0.517225 | 0.286 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 0.113963 | 0.943 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 0.139761 | 0.855 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 0.221918 | 0.654 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 0.174259 | 0.759 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 0.330695 | 0.481 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 0.231075 | 0.636 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 0.111635 | 0.952 | 1 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 0.338962 | 0.470 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 0.452476 | 0.344 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 0.452476 | 0.344 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 0.479291 | 0.319 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 0.479291 | 0.319 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 0.433452 | 0.363 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 0.433452 | 0.363 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 0.167320 | 0.776 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 0.352413 | 0.453 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 0.354287 | 0.451 | 1 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 0.257609 | 0.589 | 1 | 0 |
| MAP kinase activation | R-HSA-450294 | 0.455407 | 0.342 | 1 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 0.405808 | 0.392 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 0.310194 | 0.508 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 0.432668 | 0.364 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 0.411585 | 0.386 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 0.374893 | 0.426 | 1 | 0 |
| Signaling by WNT | R-HSA-195721 | 0.335602 | 0.474 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 0.106442 | 0.973 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 0.119234 | 0.924 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 0.224629 | 0.649 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 0.075853 | 1.120 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 0.110581 | 0.956 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 0.116530 | 0.934 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 0.153130 | 0.815 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 0.338962 | 0.470 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 0.128109 | 0.892 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 0.156096 | 0.807 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 0.276695 | 0.558 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 0.332636 | 0.478 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 0.508851 | 0.293 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 0.172159 | 0.764 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 0.484125 | 0.315 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 0.499532 | 0.301 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 0.110469 | 0.957 | 1 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 0.406236 | 0.391 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 0.204069 | 0.690 | 1 | 1 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 0.130784 | 0.883 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 0.340670 | 0.468 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 0.260010 | 0.585 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 0.260010 | 0.585 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 0.228664 | 0.641 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 0.363467 | 0.440 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 0.265544 | 0.576 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 0.394636 | 0.404 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 0.394636 | 0.404 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 0.394636 | 0.404 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 0.394636 | 0.404 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 0.424281 | 0.372 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 0.424281 | 0.372 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 0.212417 | 0.673 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 0.212417 | 0.673 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 0.222869 | 0.652 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 0.452476 | 0.344 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 0.452476 | 0.344 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 0.479291 | 0.319 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 0.479291 | 0.319 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 0.136032 | 0.866 | 1 | 0 |
| Signalling to ERKs | R-HSA-187687 | 0.352413 | 0.453 | 1 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 0.504795 | 0.297 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 0.477072 | 0.321 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 0.231075 | 0.636 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 0.374893 | 0.426 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 0.400094 | 0.398 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 0.340670 | 0.468 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 0.501599 | 0.300 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 0.411424 | 0.386 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 0.247080 | 0.607 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 0.218005 | 0.662 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 0.075372 | 1.123 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 0.254961 | 0.594 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 0.460747 | 0.337 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 0.351867 | 0.454 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 0.192191 | 0.716 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 0.126228 | 0.899 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 0.504795 | 0.297 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 0.354287 | 0.451 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 0.311646 | 0.506 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 0.257825 | 0.589 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 0.379450 | 0.421 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 0.392561 | 0.406 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 0.509005 | 0.293 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 0.296238 | 0.528 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 0.330695 | 0.481 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 0.330695 | 0.481 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 0.330695 | 0.481 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 0.191954 | 0.717 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 0.452476 | 0.344 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 0.325242 | 0.488 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 0.287908 | 0.541 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 0.197668 | 0.704 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 0.477091 | 0.321 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 0.298066 | 0.526 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 0.496016 | 0.305 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 0.496016 | 0.305 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 0.395277 | 0.403 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 0.422933 | 0.374 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 0.134961 | 0.870 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 0.484125 | 0.315 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 0.417364 | 0.379 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 0.239282 | 0.621 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 0.251521 | 0.599 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 0.199340 | 0.700 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 0.251521 | 0.599 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 0.179856 | 0.745 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 0.202108 | 0.694 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 0.169570 | 0.771 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 0.452476 | 0.344 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 0.452476 | 0.344 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 0.460747 | 0.337 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 0.432668 | 0.364 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 0.501038 | 0.300 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 0.244153 | 0.612 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 0.354287 | 0.451 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 0.484125 | 0.315 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 0.296238 | 0.528 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 0.247080 | 0.607 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 0.257609 | 0.589 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 0.409998 | 0.387 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 0.504795 | 0.297 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 0.504795 | 0.297 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 0.379450 | 0.421 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 0.489494 | 0.310 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 0.144279 | 0.841 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 0.105943 | 0.975 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 0.394636 | 0.404 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 0.106294 | 0.973 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 0.383286 | 0.416 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 0.400094 | 0.398 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 0.320753 | 0.494 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 0.374893 | 0.426 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 0.139358 | 0.856 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 0.302422 | 0.519 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 0.320753 | 0.494 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 0.373936 | 0.427 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 0.452476 | 0.344 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 0.466279 | 0.331 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 0.101563 | 0.993 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 0.493129 | 0.307 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 0.124257 | 0.906 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 0.509005 | 0.293 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 0.179856 | 0.745 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 0.460747 | 0.337 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 0.524252 | 0.280 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 0.524252 | 0.280 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 0.524252 | 0.280 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 0.529051 | 0.277 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 0.529051 | 0.277 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 0.529051 | 0.277 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 0.529051 | 0.277 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 0.529051 | 0.277 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 0.529051 | 0.277 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 0.529051 | 0.277 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 0.529051 | 0.277 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 0.529051 | 0.277 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 0.529051 | 0.277 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 0.530413 | 0.275 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 0.533241 | 0.273 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 0.536369 | 0.271 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 0.539324 | 0.268 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 0.539324 | 0.268 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 0.539324 | 0.268 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 0.552120 | 0.258 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 0.552120 | 0.258 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 0.552120 | 0.258 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 0.552120 | 0.258 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 0.552120 | 0.258 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 0.552120 | 0.258 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 0.552120 | 0.258 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 0.552120 | 0.258 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 0.552120 | 0.258 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 0.552120 | 0.258 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 0.554062 | 0.256 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 0.554062 | 0.256 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 0.554062 | 0.256 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 0.554062 | 0.256 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 0.554639 | 0.256 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 0.554639 | 0.256 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 0.554639 | 0.256 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 0.559929 | 0.252 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 0.568289 | 0.245 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 0.568463 | 0.245 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 0.569401 | 0.245 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 0.569783 | 0.244 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 0.574061 | 0.241 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 0.574061 | 0.241 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 0.574061 | 0.241 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 0.574061 | 0.241 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 0.574061 | 0.241 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 0.574061 | 0.241 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 0.574061 | 0.241 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 0.574061 | 0.241 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 0.574061 | 0.241 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 0.574061 | 0.241 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 0.579513 | 0.237 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 0.579606 | 0.237 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 0.582524 | 0.235 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 0.582524 | 0.235 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 0.582524 | 0.235 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 0.582524 | 0.235 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 0.582524 | 0.235 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 0.590009 | 0.229 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 0.594928 | 0.226 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 0.594928 | 0.226 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 0.594928 | 0.226 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 0.596245 | 0.225 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 0.596245 | 0.225 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 0.596245 | 0.225 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 0.598588 | 0.223 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 0.598588 | 0.223 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 0.602293 | 0.220 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 0.602481 | 0.220 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 0.609624 | 0.215 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 0.609624 | 0.215 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 0.609624 | 0.215 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 0.609624 | 0.215 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 0.612595 | 0.213 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 0.614774 | 0.211 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 0.614774 | 0.211 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 0.614774 | 0.211 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 0.614774 | 0.211 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 0.614774 | 0.211 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 0.614774 | 0.211 | 0 | 0 |
| FASTK family proteins regulate processing and stability of mitochondrial RNAs | R-HSA-9837092 | 0.614774 | 0.211 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 0.614774 | 0.211 | 1 | 1 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 0.614774 | 0.211 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 0.617517 | 0.209 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 0.619333 | 0.208 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 0.622663 | 0.206 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 0.622663 | 0.206 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 0.622663 | 0.206 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 0.622957 | 0.206 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 0.622957 | 0.206 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 0.625793 | 0.204 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 0.627864 | 0.202 | 1 | 1 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 0.633649 | 0.198 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 0.633649 | 0.198 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 0.633649 | 0.198 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 0.633649 | 0.198 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 0.633649 | 0.198 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 0.633649 | 0.198 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 0.633649 | 0.198 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 0.633649 | 0.198 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 0.633649 | 0.198 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 0.635363 | 0.197 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 0.635363 | 0.197 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 0.635363 | 0.197 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 0.638461 | 0.195 | 0 | 0 |
| M Phase | R-HSA-68886 | 0.639372 | 0.194 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 0.643933 | 0.191 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 0.643933 | 0.191 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 0.643933 | 0.191 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 0.646674 | 0.189 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 0.647725 | 0.189 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 0.651600 | 0.186 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 0.651600 | 0.186 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 0.651600 | 0.186 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 0.651600 | 0.186 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 0.651600 | 0.186 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 0.651600 | 0.186 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 0.651600 | 0.186 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 0.651600 | 0.186 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 0.651600 | 0.186 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 0.651600 | 0.186 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 0.653401 | 0.185 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 0.659751 | 0.181 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 0.659753 | 0.181 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 0.659753 | 0.181 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 0.659753 | 0.181 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 0.661697 | 0.179 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 0.668673 | 0.175 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 0.668673 | 0.175 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 0.668673 | 0.175 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 0.668673 | 0.175 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 0.668673 | 0.175 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 0.669224 | 0.174 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 0.669466 | 0.174 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 0.671448 | 0.173 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 0.672021 | 0.173 | 1 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 0.672697 | 0.172 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 0.672697 | 0.172 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 0.677692 | 0.169 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 0.677692 | 0.169 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 0.682816 | 0.166 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 0.682816 | 0.166 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 0.682816 | 0.166 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 0.682816 | 0.166 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 0.682816 | 0.166 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 0.682816 | 0.166 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 0.682816 | 0.166 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 0.683944 | 0.165 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 0.683944 | 0.165 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 0.684910 | 0.164 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 0.684910 | 0.164 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 0.684910 | 0.164 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 0.684910 | 0.164 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 0.684910 | 0.164 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 0.684910 | 0.164 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 0.684910 | 0.164 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 0.684910 | 0.164 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 0.684910 | 0.164 | 0 | 0 |
| PKA activation | R-HSA-163615 | 0.684910 | 0.164 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 0.684910 | 0.164 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 0.687717 | 0.163 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 0.691137 | 0.160 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 0.691137 | 0.160 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 0.693859 | 0.159 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 0.694461 | 0.158 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 0.700352 | 0.155 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 0.700352 | 0.155 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 0.700352 | 0.155 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 0.700352 | 0.155 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 0.700352 | 0.155 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 0.700352 | 0.155 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 0.701974 | 0.154 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 0.703058 | 0.153 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 0.703566 | 0.153 | 1 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 0.704583 | 0.152 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 0.704583 | 0.152 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 0.704583 | 0.152 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 0.705185 | 0.152 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 0.708888 | 0.149 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 0.714992 | 0.146 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 0.714992 | 0.146 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 0.714992 | 0.146 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 0.714992 | 0.146 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 0.715038 | 0.146 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 0.715038 | 0.146 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 0.715038 | 0.146 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 0.715038 | 0.146 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 0.715038 | 0.146 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 0.715038 | 0.146 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 0.715038 | 0.146 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 0.715038 | 0.146 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 0.715038 | 0.146 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 0.718781 | 0.143 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 0.720858 | 0.142 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 0.725796 | 0.139 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 0.725796 | 0.139 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 0.726670 | 0.139 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 0.729005 | 0.137 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 0.729005 | 0.137 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 0.729005 | 0.137 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 0.729005 | 0.137 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 0.729005 | 0.137 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 0.729005 | 0.137 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 0.729005 | 0.137 | 1 | 1 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 0.729005 | 0.137 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 0.729005 | 0.137 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 0.729005 | 0.137 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 0.731144 | 0.136 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 0.733957 | 0.134 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 0.733957 | 0.134 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 0.734887 | 0.134 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 0.734887 | 0.134 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 0.734887 | 0.134 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 0.738405 | 0.132 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 0.742289 | 0.129 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 0.742289 | 0.129 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 0.742289 | 0.129 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 0.742289 | 0.129 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 0.742289 | 0.129 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 0.742289 | 0.129 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 0.742289 | 0.129 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 0.742289 | 0.129 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 0.744383 | 0.128 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 0.744383 | 0.128 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 0.744383 | 0.128 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 0.744383 | 0.128 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 0.744383 | 0.128 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 0.744383 | 0.128 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 0.751647 | 0.124 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 0.754922 | 0.122 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 0.754922 | 0.122 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 0.754922 | 0.122 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 0.754922 | 0.122 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 0.754922 | 0.122 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 0.754922 | 0.122 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 0.756502 | 0.121 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 0.757292 | 0.121 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 0.762502 | 0.118 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 0.764023 | 0.117 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 0.766937 | 0.115 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 0.766937 | 0.115 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 0.766937 | 0.115 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 0.766937 | 0.115 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 0.766937 | 0.115 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 0.766937 | 0.115 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 0.766937 | 0.115 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 0.766937 | 0.115 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 0.766937 | 0.115 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 0.766937 | 0.115 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 0.766937 | 0.115 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 0.768663 | 0.114 | 1 | 0 |
| GPER1 signaling | R-HSA-9634597 | 0.771137 | 0.113 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 0.778363 | 0.109 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 0.778363 | 0.109 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 0.778363 | 0.109 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 0.778363 | 0.109 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 0.778363 | 0.109 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 0.778363 | 0.109 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 0.778363 | 0.109 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 0.778363 | 0.109 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 0.778946 | 0.108 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 0.785802 | 0.105 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 0.789230 | 0.103 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 0.789230 | 0.103 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 0.789230 | 0.103 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 0.789230 | 0.103 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 0.789230 | 0.103 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 0.789230 | 0.103 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 0.789230 | 0.103 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 0.789230 | 0.103 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 0.792480 | 0.101 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 0.795416 | 0.099 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 0.795759 | 0.099 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 0.795759 | 0.099 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 0.795759 | 0.099 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 0.795759 | 0.099 | 1 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 0.796318 | 0.099 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 0.799564 | 0.097 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 0.799564 | 0.097 | 1 | 1 |
| Metalloprotease DUBs | R-HSA-5689901 | 0.799564 | 0.097 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 0.799564 | 0.097 | 0 | 0 |
| Attachment of bacteria to epithelial cells | R-HSA-9638630 | 0.799564 | 0.097 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 0.799564 | 0.097 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 0.799564 | 0.097 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 0.799564 | 0.097 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 0.802988 | 0.095 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 0.802988 | 0.095 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 0.802988 | 0.095 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 0.802988 | 0.095 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 0.807044 | 0.093 | 0 | 0 |
| Cobalamin (Cbl) metabolism | R-HSA-9759218 | 0.809393 | 0.092 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 0.809393 | 0.092 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 0.809393 | 0.092 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 0.809393 | 0.092 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 0.809393 | 0.092 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 0.810311 | 0.091 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 0.810311 | 0.091 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 0.810311 | 0.091 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 0.811482 | 0.091 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 0.816404 | 0.088 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 0.818740 | 0.087 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 0.818740 | 0.087 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 0.818740 | 0.087 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 0.818740 | 0.087 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 0.824230 | 0.084 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 0.827629 | 0.082 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 0.827629 | 0.082 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 0.827629 | 0.082 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 0.827629 | 0.082 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 0.827629 | 0.082 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 0.827629 | 0.082 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 0.827629 | 0.082 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 0.827629 | 0.082 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 0.828088 | 0.082 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 0.828991 | 0.081 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 0.833041 | 0.079 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 0.836083 | 0.078 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 0.836083 | 0.078 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 0.836083 | 0.078 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 0.837875 | 0.077 | 1 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 0.839874 | 0.076 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 0.842591 | 0.074 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 0.844122 | 0.074 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 0.844122 | 0.074 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 0.844122 | 0.074 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 0.844122 | 0.074 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 0.844122 | 0.074 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 0.845087 | 0.073 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 0.847191 | 0.072 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 0.847191 | 0.072 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 0.849344 | 0.071 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 0.849344 | 0.071 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 0.851677 | 0.070 | 1 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 0.851768 | 0.070 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 0.851768 | 0.070 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 0.851768 | 0.070 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 0.851768 | 0.070 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 0.855091 | 0.068 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 0.855091 | 0.068 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 0.855091 | 0.068 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 0.856052 | 0.068 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 0.856052 | 0.068 | 1 | 0 |
| DNA Repair | R-HSA-73894 | 0.856716 | 0.067 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 0.859040 | 0.066 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 0.859040 | 0.066 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 0.859040 | 0.066 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 0.859040 | 0.066 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 0.859040 | 0.066 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 0.859040 | 0.066 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 0.859040 | 0.066 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 0.859040 | 0.066 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 0.859826 | 0.066 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 0.860316 | 0.065 | 1 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 0.860316 | 0.065 | 1 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 0.860637 | 0.065 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 0.861342 | 0.065 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 0.862399 | 0.064 | 1 | 0 |
| Selective autophagy | R-HSA-9663891 | 0.864493 | 0.063 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 0.865955 | 0.063 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 0.865955 | 0.063 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 0.865955 | 0.063 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 0.865955 | 0.063 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 0.865955 | 0.063 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 0.865988 | 0.062 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 0.865988 | 0.062 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 0.867280 | 0.062 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 0.868338 | 0.061 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 0.871150 | 0.060 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 0.871724 | 0.060 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 0.872466 | 0.059 | 1 | 0 |
| eNOS activation | R-HSA-203615 | 0.872531 | 0.059 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 0.872531 | 0.059 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 0.872531 | 0.059 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 0.872531 | 0.059 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 0.872531 | 0.059 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 0.872531 | 0.059 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 0.872531 | 0.059 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 0.872531 | 0.059 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 0.872531 | 0.059 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 0.872531 | 0.059 | 1 | 1 |
| Neurotransmitter release cycle | R-HSA-112310 | 0.873370 | 0.059 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 0.873370 | 0.059 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 0.878785 | 0.056 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 0.878785 | 0.056 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 0.878785 | 0.056 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 0.882814 | 0.054 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 0.883693 | 0.054 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 0.884732 | 0.053 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 0.884732 | 0.053 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 0.884732 | 0.053 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 0.884732 | 0.053 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 0.884732 | 0.053 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 0.884732 | 0.053 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 0.884821 | 0.053 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 0.885334 | 0.053 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 0.885721 | 0.053 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 0.889592 | 0.051 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 0.890388 | 0.050 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 0.890388 | 0.050 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 0.890388 | 0.050 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 0.890388 | 0.050 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 0.890692 | 0.050 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 0.893346 | 0.049 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 0.894051 | 0.049 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 0.894166 | 0.049 | 1 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 0.895767 | 0.048 | 0 | 0 |
| tRNA processing in the mitochondrion | R-HSA-6785470 | 0.895767 | 0.048 | 0 | 0 |
| Depurination | R-HSA-73927 | 0.895767 | 0.048 | 0 | 0 |
| Biofilm formation | R-HSA-9931953 | 0.895767 | 0.048 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 0.895767 | 0.048 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 0.897314 | 0.047 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 0.900499 | 0.046 | 1 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 0.900499 | 0.046 | 1 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 0.900882 | 0.045 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 0.900882 | 0.045 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 0.900882 | 0.045 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 0.902451 | 0.045 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 0.902451 | 0.045 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 0.902451 | 0.045 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 0.903929 | 0.044 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 0.904248 | 0.044 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 0.905746 | 0.043 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 0.905746 | 0.043 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 0.906295 | 0.043 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 0.906295 | 0.043 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 0.906295 | 0.043 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 0.906597 | 0.043 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 0.909521 | 0.041 | 1 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 0.909521 | 0.041 | 1 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 0.909997 | 0.041 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 0.909997 | 0.041 | 1 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 0.910372 | 0.041 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 0.910372 | 0.041 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 0.910372 | 0.041 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 0.910372 | 0.041 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 0.910372 | 0.041 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 0.910809 | 0.041 | 1 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 0.912363 | 0.040 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 0.913561 | 0.039 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 0.913561 | 0.039 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 0.913561 | 0.039 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 0.914772 | 0.039 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 0.915125 | 0.039 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 0.916993 | 0.038 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 0.918955 | 0.037 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 0.918955 | 0.037 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 0.920297 | 0.036 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 0.920297 | 0.036 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 0.922326 | 0.035 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 0.922934 | 0.035 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 0.922934 | 0.035 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 0.923476 | 0.035 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 0.924734 | 0.034 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 0.925412 | 0.034 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 0.926354 | 0.033 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 0.926717 | 0.033 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 0.926717 | 0.033 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 0.926717 | 0.033 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 0.929480 | 0.032 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 0.929480 | 0.032 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 0.930315 | 0.031 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 0.930315 | 0.031 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 0.930315 | 0.031 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 0.930315 | 0.031 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 0.932691 | 0.030 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 0.933736 | 0.030 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 0.933736 | 0.030 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 0.933736 | 0.030 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 0.934563 | 0.029 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 0.935037 | 0.029 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 0.936990 | 0.028 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 0.936990 | 0.028 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 0.940043 | 0.027 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 0.940084 | 0.027 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 0.940746 | 0.027 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 0.943026 | 0.025 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 0.943026 | 0.025 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 0.943026 | 0.025 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 0.945824 | 0.024 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 0.945824 | 0.024 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 0.945824 | 0.024 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 0.947857 | 0.023 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 0.947857 | 0.023 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 0.947857 | 0.023 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 0.948485 | 0.023 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 0.948485 | 0.023 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 0.948801 | 0.023 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 0.951015 | 0.022 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 0.953377 | 0.021 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 0.953421 | 0.021 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 0.953421 | 0.021 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 0.954719 | 0.020 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 0.954719 | 0.020 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 0.954719 | 0.020 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 0.955287 | 0.020 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 0.955709 | 0.020 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 0.956234 | 0.019 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 0.957885 | 0.019 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 0.957885 | 0.019 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 0.958161 | 0.019 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 0.958786 | 0.018 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 0.959954 | 0.018 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 0.960578 | 0.017 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 0.961921 | 0.017 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 0.962205 | 0.017 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 0.963766 | 0.016 | 0 | 0 |
| Protein folding | R-HSA-391251 | 0.963766 | 0.016 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 0.964950 | 0.015 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 0.965266 | 0.015 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 0.965408 | 0.015 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 0.966772 | 0.015 | 1 | 0 |
| Kinesins | R-HSA-983189 | 0.967263 | 0.014 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 0.968088 | 0.014 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 0.968088 | 0.014 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 0.968872 | 0.014 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 0.968872 | 0.014 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 0.968872 | 0.014 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 0.969415 | 0.013 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 0.969415 | 0.013 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 0.969415 | 0.013 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 0.970402 | 0.013 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 0.970402 | 0.013 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 0.970689 | 0.013 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 0.970689 | 0.013 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 0.970689 | 0.013 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 0.971857 | 0.012 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 0.971857 | 0.012 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 0.971912 | 0.012 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 0.972104 | 0.012 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 0.973240 | 0.012 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 0.973240 | 0.012 | 1 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 0.973363 | 0.012 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 0.974555 | 0.011 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 0.975291 | 0.011 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 0.975323 | 0.011 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 0.975806 | 0.011 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 0.976311 | 0.010 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 0.976328 | 0.010 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 0.976995 | 0.010 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 0.976995 | 0.010 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 0.977677 | 0.010 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 0.977880 | 0.010 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 0.978126 | 0.010 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 0.978276 | 0.010 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 0.979739 | 0.009 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 0.979997 | 0.009 | 1 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 0.981197 | 0.008 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 0.981197 | 0.008 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 0.981197 | 0.008 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 0.982122 | 0.008 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 0.982492 | 0.008 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 0.983081 | 0.007 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 0.983234 | 0.007 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 0.983234 | 0.007 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 0.983777 | 0.007 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 0.983777 | 0.007 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 0.983946 | 0.007 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 0.984628 | 0.007 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 0.985372 | 0.006 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 0.985388 | 0.006 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 0.985897 | 0.006 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 0.986107 | 0.006 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 0.986128 | 0.006 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 0.986709 | 0.006 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 0.986790 | 0.006 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 0.986790 | 0.006 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 0.987005 | 0.006 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 0.987638 | 0.005 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 0.987823 | 0.005 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 0.988019 | 0.005 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 0.988342 | 0.005 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 0.988645 | 0.005 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 0.988674 | 0.005 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 0.989160 | 0.005 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 0.989160 | 0.005 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 0.989340 | 0.005 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 0.989735 | 0.004 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 0.990445 | 0.004 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 0.990721 | 0.004 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 0.990820 | 0.004 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 0.991676 | 0.004 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 0.992025 | 0.003 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 0.993077 | 0.003 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 0.993140 | 0.003 | 1 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 0.993146 | 0.003 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 0.993146 | 0.003 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 0.993352 | 0.003 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 0.994091 | 0.003 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 0.994109 | 0.003 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 0.994542 | 0.002 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 0.995424 | 0.002 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 0.995761 | 0.002 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 0.995863 | 0.002 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 0.995863 | 0.002 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 0.996067 | 0.002 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 0.996261 | 0.002 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 0.996357 | 0.002 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 0.996403 | 0.002 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 0.996403 | 0.002 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 0.996403 | 0.002 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 0.996427 | 0.002 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 0.996427 | 0.002 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 0.996427 | 0.002 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 0.996445 | 0.002 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 0.997627 | 0.001 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 0.997653 | 0.001 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 0.997856 | 0.001 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 0.997961 | 0.001 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 0.998012 | 0.001 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 0.998185 | 0.001 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 0.998185 | 0.001 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 0.998407 | 0.001 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 0.998495 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 0.998640 | 0.001 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 0.998815 | 0.001 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 0.998889 | 0.000 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 0.998949 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 0.998978 | 0.000 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 0.999045 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 0.999180 | 0.000 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 0.999272 | 0.000 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 0.999284 | 0.000 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 0.999298 | 0.000 | 1 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 0.999395 | 0.000 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 0.999422 | 0.000 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 0.999547 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 0.999600 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 0.999616 | 0.000 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 0.999616 | 0.000 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 0.999632 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 0.999757 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 0.999767 | 0.000 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 0.999811 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 0.999819 | 0.000 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 0.999821 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 0.999866 | 0.000 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 0.999871 | 0.000 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 0.999881 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 0.999912 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 0.999925 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 0.999952 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 0.999953 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 0.999957 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 0.999958 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 0.999967 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 0.999978 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 0.999987 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 0.999989 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 0.999991 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 0.999994 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 0.999994 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 0.999995 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 0.999998 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 0.999999 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 0.999999 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 1.000000 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.000000 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 1.000000 | 0.000 | 1 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000 | 0.000 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.000000 | 0.000 | 1 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000 | 0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000 | -0.000 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 1.000000 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.110223e-16 | 15.955 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.776357e-15 | 14.750 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 6.513678e-13 | 12.186 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.375433e-12 | 11.624 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 3.553713e-12 | 11.449 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 3.663847e-12 | 11.436 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 2.009704e-11 | 10.697 | 1 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.523348e-11 | 10.598 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.076086e-10 | 9.968 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 2.709073e-10 | 9.567 | 1 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.107948e-09 | 8.955 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 2.062842e-09 | 8.686 | 0 | 0 |
| M Phase | R-HSA-68886 | 3.566924e-09 | 8.448 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 4.293992e-09 | 8.367 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 8.031022e-09 | 8.095 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 8.223545e-09 | 8.085 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 7.411111e-09 | 8.130 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 1.562547e-08 | 7.806 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.819481e-08 | 7.740 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.790643e-08 | 7.747 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 2.065844e-08 | 7.685 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 2.130682e-08 | 7.671 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 2.675315e-08 | 7.573 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 6.353025e-08 | 7.197 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 7.510547e-08 | 7.124 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 7.417710e-08 | 7.130 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 8.468465e-08 | 7.072 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.028388e-07 | 6.988 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.369517e-07 | 6.863 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.482697e-07 | 6.829 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.460131e-07 | 6.836 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.115174e-07 | 6.675 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 2.242683e-07 | 6.649 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 2.453904e-07 | 6.610 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 2.442095e-07 | 6.612 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.780388e-07 | 6.556 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 2.981619e-07 | 6.526 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 3.374738e-07 | 6.472 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 4.009407e-07 | 6.397 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 6.285155e-07 | 6.202 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 6.222769e-07 | 6.206 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 8.370148e-07 | 6.077 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 9.798039e-07 | 6.009 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.186810e-06 | 5.926 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.186810e-06 | 5.926 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 1.415782e-06 | 5.849 | 1 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 1.441858e-06 | 5.841 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 2.292086e-06 | 5.640 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 2.305440e-06 | 5.637 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 2.488997e-06 | 5.604 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.515565e-06 | 5.599 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 2.574684e-06 | 5.589 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 3.162181e-06 | 5.500 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 3.335352e-06 | 5.477 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 4.294288e-06 | 5.367 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 4.432276e-06 | 5.353 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 4.511989e-06 | 5.346 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 4.944282e-06 | 5.306 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 5.422938e-06 | 5.266 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 5.462053e-06 | 5.263 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 5.699457e-06 | 5.244 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 5.691979e-06 | 5.245 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 5.843008e-06 | 5.233 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 7.336307e-06 | 5.135 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 7.529824e-06 | 5.123 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 9.766725e-06 | 5.010 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 1.000345e-05 | 5.000 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.091763e-05 | 4.962 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.148678e-05 | 4.940 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.370278e-05 | 4.863 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 2.099955e-05 | 4.678 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 2.735039e-05 | 4.563 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 2.870291e-05 | 4.542 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 3.094919e-05 | 4.509 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 3.316624e-05 | 4.479 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 3.524500e-05 | 4.453 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 3.370383e-05 | 4.472 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 3.764328e-05 | 4.424 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 4.025814e-05 | 4.395 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 4.728920e-05 | 4.325 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 4.728920e-05 | 4.325 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 4.945517e-05 | 4.306 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 5.326387e-05 | 4.274 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 6.532322e-05 | 4.185 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 6.532322e-05 | 4.185 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 7.083458e-05 | 4.150 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 7.254051e-05 | 4.139 | 1 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 7.638012e-05 | 4.117 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 7.638012e-05 | 4.117 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 8.993689e-05 | 4.046 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.011579e-04 | 3.995 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.224332e-04 | 3.912 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.275685e-04 | 3.894 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 1.362817e-04 | 3.866 | 0 | 0 |
| Kinesins | R-HSA-983189 | 1.705593e-04 | 3.768 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.706616e-04 | 3.768 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 1.799951e-04 | 3.745 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.029467e-04 | 3.693 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 2.222191e-04 | 3.653 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.587134e-04 | 3.587 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 3.207355e-04 | 3.494 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 3.710580e-04 | 3.431 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.045064e-04 | 3.393 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 4.183942e-04 | 3.378 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 4.707688e-04 | 3.327 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 4.821040e-04 | 3.317 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 5.029752e-04 | 3.298 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 5.297491e-04 | 3.276 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 5.514404e-04 | 3.259 | 0 | 0 |
| Protein folding | R-HSA-391251 | 5.738521e-04 | 3.241 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 6.412436e-04 | 3.193 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 6.413366e-04 | 3.193 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 6.895721e-04 | 3.161 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 6.924315e-04 | 3.160 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 7.312330e-04 | 3.136 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 7.424346e-04 | 3.129 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 8.165273e-04 | 3.088 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 8.181613e-04 | 3.087 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 8.181613e-04 | 3.087 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 8.945137e-04 | 3.048 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 9.646335e-04 | 3.016 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.029525e-03 | 2.987 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.035529e-03 | 2.985 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 1.046671e-03 | 2.980 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.060088e-03 | 2.975 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 1.166624e-03 | 2.933 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 1.166624e-03 | 2.933 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.095441e-03 | 2.960 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.095441e-03 | 2.960 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.096642e-03 | 2.960 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.271756e-03 | 2.896 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.303886e-03 | 2.885 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 1.375995e-03 | 2.861 | 1 | 0 |
| Signal Transduction | R-HSA-162582 | 1.376753e-03 | 2.861 | 1 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.410178e-03 | 2.851 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.417821e-03 | 2.848 | 1 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.488330e-03 | 2.827 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 1.558804e-03 | 2.807 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.766566e-03 | 2.753 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.979377e-03 | 2.703 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.979377e-03 | 2.703 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.896193e-03 | 2.722 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.982781e-03 | 2.703 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.983736e-03 | 2.703 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 2.055733e-03 | 2.687 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.142167e-03 | 2.669 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 2.389842e-03 | 2.622 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 2.486414e-03 | 2.604 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 2.651607e-03 | 2.576 | 1 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.899782e-03 | 2.538 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.950707e-03 | 2.530 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.899782e-03 | 2.538 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.899782e-03 | 2.538 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 2.786072e-03 | 2.555 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.899782e-03 | 2.538 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 2.778837e-03 | 2.556 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 2.778837e-03 | 2.556 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 2.815174e-03 | 2.550 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 2.850586e-03 | 2.545 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 2.993250e-03 | 2.524 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 3.040049e-03 | 2.517 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 3.492786e-03 | 2.457 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 3.801334e-03 | 2.420 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 3.801334e-03 | 2.420 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 3.808943e-03 | 2.419 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 3.914247e-03 | 2.407 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 4.151615e-03 | 2.382 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 4.247317e-03 | 2.372 | 1 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 4.637338e-03 | 2.334 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 4.631009e-03 | 2.334 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 4.469737e-03 | 2.350 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 4.637338e-03 | 2.334 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 4.476038e-03 | 2.349 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 4.827854e-03 | 2.316 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 4.469737e-03 | 2.350 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 4.630363e-03 | 2.334 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 4.750118e-03 | 2.323 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 5.356064e-03 | 2.271 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 5.477003e-03 | 2.261 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 6.291017e-03 | 2.201 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 6.385392e-03 | 2.195 | 1 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 6.576045e-03 | 2.182 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 6.699899e-03 | 2.174 | 1 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 6.769639e-03 | 2.169 | 1 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 6.787239e-03 | 2.168 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 6.787239e-03 | 2.168 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 6.798426e-03 | 2.168 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 7.262778e-03 | 2.139 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 7.262778e-03 | 2.139 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 7.262778e-03 | 2.139 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 7.262778e-03 | 2.139 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 7.915409e-03 | 2.102 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 7.785626e-03 | 2.109 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 7.113623e-03 | 2.148 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 8.134586e-03 | 2.090 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 8.283214e-03 | 2.082 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 8.438148e-03 | 2.074 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 8.805433e-03 | 2.055 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 8.824467e-03 | 2.054 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 9.541648e-03 | 2.020 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 9.546907e-03 | 2.020 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 9.546907e-03 | 2.020 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 9.581726e-03 | 2.019 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 9.830981e-03 | 2.007 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 9.931117e-03 | 2.003 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 9.976946e-03 | 2.001 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 1.045738e-02 | 1.981 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.115969e-02 | 1.952 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 1.128143e-02 | 1.948 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 1.321425e-02 | 1.879 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.321425e-02 | 1.879 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 1.208775e-02 | 1.918 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.319316e-02 | 1.880 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.256158e-02 | 1.901 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 1.191108e-02 | 1.924 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.311101e-02 | 1.882 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.253070e-02 | 1.902 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.213150e-02 | 1.916 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.344469e-02 | 1.871 | 1 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.402804e-02 | 1.853 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.432380e-02 | 1.844 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.534411e-02 | 1.814 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.562088e-02 | 1.806 | 1 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.600461e-02 | 1.796 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.650498e-02 | 1.782 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.650498e-02 | 1.782 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.650498e-02 | 1.782 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.650498e-02 | 1.782 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.650498e-02 | 1.782 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.650498e-02 | 1.782 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.650498e-02 | 1.782 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.663655e-02 | 1.779 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.674463e-02 | 1.776 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.709618e-02 | 1.767 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.792700e-02 | 1.746 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 1.946312e-02 | 1.711 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 2.001745e-02 | 1.699 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.096725e-02 | 1.678 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 2.096725e-02 | 1.678 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 2.127937e-02 | 1.672 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 2.127937e-02 | 1.672 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 2.323372e-02 | 1.634 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 2.261607e-02 | 1.646 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 2.261607e-02 | 1.646 | 1 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.467765e-02 | 1.608 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 2.589011e-02 | 1.587 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 2.331982e-02 | 1.632 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 2.296561e-02 | 1.639 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 2.467765e-02 | 1.608 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 2.473477e-02 | 1.607 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 2.611244e-02 | 1.583 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 2.617611e-02 | 1.582 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 2.627487e-02 | 1.580 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 2.628604e-02 | 1.580 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 2.628604e-02 | 1.580 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 2.628604e-02 | 1.580 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 2.648107e-02 | 1.577 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 2.701472e-02 | 1.568 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 2.701472e-02 | 1.568 | 1 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 2.820957e-02 | 1.550 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 2.820957e-02 | 1.550 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 2.848500e-02 | 1.545 | 1 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 2.887174e-02 | 1.540 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 3.021902e-02 | 1.520 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 3.046177e-02 | 1.516 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 3.055267e-02 | 1.515 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 3.055267e-02 | 1.515 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 3.092300e-02 | 1.510 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 3.139385e-02 | 1.503 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 3.150196e-02 | 1.502 | 0 | 0 |
| IRS activation | R-HSA-74713 | 3.150196e-02 | 1.502 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 3.150196e-02 | 1.502 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 3.150196e-02 | 1.502 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 3.206302e-02 | 1.494 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 3.206302e-02 | 1.494 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 3.239556e-02 | 1.490 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 3.352251e-02 | 1.475 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 3.438445e-02 | 1.464 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.486225e-02 | 1.458 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.486225e-02 | 1.458 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 3.652876e-02 | 1.437 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 3.714808e-02 | 1.430 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 3.864653e-02 | 1.413 | 1 | 1 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 3.869214e-02 | 1.412 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 3.881469e-02 | 1.411 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 3.881469e-02 | 1.411 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 3.908439e-02 | 1.408 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 3.932225e-02 | 1.405 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.932225e-02 | 1.405 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 3.932225e-02 | 1.405 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 4.001008e-02 | 1.398 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 4.884039e-02 | 1.311 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 4.708410e-02 | 1.327 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 4.315131e-02 | 1.365 | 1 | 1 |
| HDACs deacetylate histones | R-HSA-3214815 | 4.669462e-02 | 1.331 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 4.905019e-02 | 1.309 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.315131e-02 | 1.365 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 4.385507e-02 | 1.358 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 4.736160e-02 | 1.325 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 4.465574e-02 | 1.350 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 5.004800e-02 | 1.301 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 5.054951e-02 | 1.296 | 1 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 5.109017e-02 | 1.292 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 5.624752e-02 | 1.250 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 5.758296e-02 | 1.240 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 5.758296e-02 | 1.240 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 5.808361e-02 | 1.236 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 5.808361e-02 | 1.236 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 5.821352e-02 | 1.235 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 5.821352e-02 | 1.235 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 5.821352e-02 | 1.235 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.825785e-02 | 1.235 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 5.825785e-02 | 1.235 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 6.064930e-02 | 1.217 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 6.096335e-02 | 1.215 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 6.136245e-02 | 1.212 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 6.136245e-02 | 1.212 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 6.168123e-02 | 1.210 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 6.329552e-02 | 1.199 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 6.398563e-02 | 1.194 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 6.411758e-02 | 1.193 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 6.514357e-02 | 1.186 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 6.527573e-02 | 1.185 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 6.591642e-02 | 1.181 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 6.841164e-02 | 1.165 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 6.953936e-02 | 1.158 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 7.176636e-02 | 1.144 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 7.198187e-02 | 1.143 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 7.198187e-02 | 1.143 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.198187e-02 | 1.143 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 7.458233e-02 | 1.127 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 7.458233e-02 | 1.127 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.458938e-02 | 1.127 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 7.529221e-02 | 1.123 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 7.543633e-02 | 1.122 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 7.543633e-02 | 1.122 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 7.720492e-02 | 1.112 | 1 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 8.530648e-02 | 1.069 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 8.530648e-02 | 1.069 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 8.530648e-02 | 1.069 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 8.548122e-02 | 1.068 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 8.655534e-02 | 1.063 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 8.861495e-02 | 1.052 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 8.963847e-02 | 1.048 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 9.233451e-02 | 1.035 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.157440e-01 | 0.937 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.157440e-01 | 0.937 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.157440e-01 | 0.937 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.157440e-01 | 0.937 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 9.270018e-02 | 1.033 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.124216e-01 | 0.949 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.124216e-01 | 0.949 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 9.848014e-02 | 1.007 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 9.780784e-02 | 1.010 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 1.075042e-01 | 0.969 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 1.075042e-01 | 0.969 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 9.498326e-02 | 1.022 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.090554e-01 | 0.962 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 1.196475e-01 | 0.922 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.131610e-01 | 0.946 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 1.111841e-01 | 0.954 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.176941e-01 | 0.929 | 0 | 0 |
| S Phase | R-HSA-69242 | 9.162942e-02 | 1.038 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 1.041315e-01 | 0.982 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.072863e-02 | 1.042 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 9.953161e-02 | 1.002 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.033554e-01 | 0.986 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 9.459868e-02 | 1.024 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 9.848014e-02 | 1.007 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 9.914643e-02 | 1.004 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 1.152145e-01 | 0.938 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.200922e-01 | 0.920 | 1 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.157440e-01 | 0.937 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.157440e-01 | 0.937 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 9.973758e-02 | 1.001 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 1.124216e-01 | 0.949 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 1.048468e-01 | 0.979 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 9.914643e-02 | 1.004 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 9.914643e-02 | 1.004 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 1.152145e-01 | 0.938 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.166166e-01 | 0.933 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.213732e-01 | 0.916 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 1.213931e-01 | 0.916 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 1.245866e-01 | 0.905 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 1.246350e-01 | 0.904 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 1.246350e-01 | 0.904 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 1.279523e-01 | 0.893 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 1.280612e-01 | 0.893 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.296141e-01 | 0.887 | 1 | 1 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.298054e-01 | 0.887 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.316679e-01 | 0.881 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.316679e-01 | 0.881 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 1.335733e-01 | 0.874 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.335733e-01 | 0.874 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 1.335733e-01 | 0.874 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.335733e-01 | 0.874 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.369148e-01 | 0.864 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 1.369885e-01 | 0.863 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 1.369885e-01 | 0.863 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.378571e-01 | 0.861 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.405226e-01 | 0.852 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 1.405226e-01 | 0.852 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 1.405226e-01 | 0.852 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.405226e-01 | 0.852 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 1.421252e-01 | 0.847 | 1 | 0 |
| G1/S Transition | R-HSA-69206 | 1.421573e-01 | 0.847 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.434400e-01 | 0.843 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.474479e-01 | 0.831 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.475825e-01 | 0.831 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 1.475825e-01 | 0.831 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 1.482170e-01 | 0.829 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 1.482170e-01 | 0.829 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.482170e-01 | 0.829 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 1.482170e-01 | 0.829 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 1.482170e-01 | 0.829 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.482170e-01 | 0.829 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 1.490217e-01 | 0.827 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 1.490217e-01 | 0.827 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 1.490217e-01 | 0.827 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 1.490217e-01 | 0.827 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 1.490217e-01 | 0.827 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 1.507256e-01 | 0.822 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 1.507256e-01 | 0.822 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.552101e-01 | 0.809 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.556188e-01 | 0.808 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.556634e-01 | 0.808 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.556634e-01 | 0.808 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 1.559695e-01 | 0.807 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.569141e-01 | 0.804 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.569141e-01 | 0.804 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.582840e-01 | 0.801 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 1.761483e-01 | 0.754 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.761483e-01 | 0.754 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 1.761483e-01 | 0.754 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.761483e-01 | 0.754 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.761483e-01 | 0.754 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.761483e-01 | 0.754 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 1.822347e-01 | 0.739 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.822347e-01 | 0.739 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.172355e-01 | 0.663 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 2.172355e-01 | 0.663 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 2.172355e-01 | 0.663 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 1.794239e-01 | 0.746 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 1.794239e-01 | 0.746 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 1.794239e-01 | 0.746 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 2.037533e-01 | 0.691 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 2.037533e-01 | 0.691 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 2.037533e-01 | 0.691 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 2.037533e-01 | 0.691 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 2.037533e-01 | 0.691 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 2.037533e-01 | 0.691 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 2.037533e-01 | 0.691 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 1.671948e-01 | 0.777 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 2.287804e-01 | 0.641 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 1.861025e-01 | 0.730 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 1.690783e-01 | 0.772 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 2.056582e-01 | 0.687 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.056582e-01 | 0.687 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 2.257743e-01 | 0.646 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 2.257743e-01 | 0.646 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.186924e-01 | 0.660 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.186924e-01 | 0.660 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.954474e-01 | 0.709 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.361437e-01 | 0.627 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.361437e-01 | 0.627 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 2.102945e-01 | 0.677 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 2.410901e-01 | 0.618 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 2.303498e-01 | 0.638 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 2.433707e-01 | 0.614 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 2.433707e-01 | 0.614 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 2.433707e-01 | 0.614 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 1.791609e-01 | 0.747 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 2.214462e-01 | 0.655 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 2.410901e-01 | 0.618 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.880282e-01 | 0.726 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.810140e-01 | 0.742 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 1.794239e-01 | 0.746 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 1.810140e-01 | 0.742 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 1.861025e-01 | 0.730 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 1.975045e-01 | 0.704 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 1.863134e-01 | 0.730 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.700726e-01 | 0.769 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.794239e-01 | 0.746 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 2.037533e-01 | 0.691 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 2.148047e-01 | 0.668 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 1.969982e-01 | 0.706 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.969982e-01 | 0.706 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 1.632037e-01 | 0.787 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.631143e-01 | 0.788 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 1.687034e-01 | 0.773 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.822347e-01 | 0.739 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.810140e-01 | 0.742 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 2.076593e-01 | 0.683 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 2.287804e-01 | 0.641 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 1.822347e-01 | 0.739 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 1.780670e-01 | 0.749 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 2.172355e-01 | 0.663 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.861025e-01 | 0.730 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 2.255206e-01 | 0.647 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 2.066229e-01 | 0.685 | 1 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 2.056582e-01 | 0.687 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 2.089211e-01 | 0.680 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 1.872366e-01 | 0.728 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.983186e-01 | 0.703 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.761483e-01 | 0.754 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.761483e-01 | 0.754 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 2.287804e-01 | 0.641 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 2.289541e-01 | 0.640 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.933829e-01 | 0.714 | 1 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 2.255206e-01 | 0.647 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.409980e-01 | 0.618 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 1.837771e-01 | 0.736 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 1.973531e-01 | 0.705 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 2.431010e-01 | 0.614 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.425438e-01 | 0.615 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.257743e-01 | 0.646 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 2.287804e-01 | 0.641 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.631143e-01 | 0.788 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.178307e-01 | 0.662 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 2.255076e-01 | 0.647 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.737017e-01 | 0.760 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 2.209042e-01 | 0.656 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 2.296715e-01 | 0.639 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 2.410901e-01 | 0.618 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.707396e-01 | 0.768 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.861025e-01 | 0.730 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.410901e-01 | 0.618 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 2.069515e-01 | 0.684 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 1.878400e-01 | 0.726 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 2.166056e-01 | 0.664 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 2.522272e-01 | 0.598 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.522272e-01 | 0.598 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.522272e-01 | 0.598 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 2.522272e-01 | 0.598 | 0 | 0 |
| Defective MMADHC causes MMAHCD | R-HSA-3359473 | 2.522272e-01 | 0.598 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.522272e-01 | 0.598 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.522272e-01 | 0.598 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.212847e-01 | 0.493 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 3.212847e-01 | 0.493 | 0 | 0 |
| Glycogen storage disease type IV (GBE1) | R-HSA-3878781 | 3.212847e-01 | 0.493 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.212847e-01 | 0.493 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.212847e-01 | 0.493 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.212847e-01 | 0.493 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.212847e-01 | 0.493 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 3.212847e-01 | 0.493 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 3.212847e-01 | 0.493 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.527482e-01 | 0.597 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.527482e-01 | 0.597 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.527482e-01 | 0.597 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 2.527482e-01 | 0.597 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 2.527482e-01 | 0.597 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 3.839684e-01 | 0.416 | 0 | 0 |
| Defective MMACHC causes MAHCC | R-HSA-3359474 | 3.839684e-01 | 0.416 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 3.839684e-01 | 0.416 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.839684e-01 | 0.416 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 3.839684e-01 | 0.416 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.839684e-01 | 0.416 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 3.839684e-01 | 0.416 | 0 | 0 |
| RSK activation | R-HSA-444257 | 2.883801e-01 | 0.540 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.883801e-01 | 0.540 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 2.543363e-01 | 0.595 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 2.543363e-01 | 0.595 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 3.238067e-01 | 0.490 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 3.238067e-01 | 0.490 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 3.238067e-01 | 0.490 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 3.238067e-01 | 0.490 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 3.238067e-01 | 0.490 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 4.408662e-01 | 0.356 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 4.408662e-01 | 0.356 | 0 | 0 |
| Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate | R-HSA-2978092 | 4.408662e-01 | 0.356 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.408662e-01 | 0.356 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 4.408662e-01 | 0.356 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 4.408662e-01 | 0.356 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.408662e-01 | 0.356 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 2.802620e-01 | 0.552 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 2.802620e-01 | 0.552 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 2.463634e-01 | 0.608 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.587623e-01 | 0.445 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 3.587623e-01 | 0.445 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 3.587623e-01 | 0.445 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 3.587623e-01 | 0.445 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 3.587623e-01 | 0.445 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.539634e-01 | 0.595 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 2.539634e-01 | 0.595 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.326407e-01 | 0.478 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 3.326407e-01 | 0.478 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 4.925119e-01 | 0.308 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.925119e-01 | 0.308 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.925119e-01 | 0.308 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 4.925119e-01 | 0.308 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 2.720980e-01 | 0.565 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 3.588320e-01 | 0.445 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 3.588320e-01 | 0.445 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 2.731130e-01 | 0.564 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 3.317641e-01 | 0.479 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.264438e-01 | 0.370 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 4.264438e-01 | 0.370 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 3.091007e-01 | 0.510 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 3.848697e-01 | 0.415 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 3.848697e-01 | 0.415 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 2.721660e-01 | 0.565 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 3.278653e-01 | 0.484 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 3.060691e-01 | 0.514 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 2.701016e-01 | 0.568 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 2.837698e-01 | 0.547 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 3.020779e-01 | 0.520 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 4.106524e-01 | 0.387 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 4.588648e-01 | 0.338 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 4.588648e-01 | 0.338 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 3.968394e-01 | 0.401 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 2.692464e-01 | 0.570 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.322981e-01 | 0.478 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 3.635670e-01 | 0.439 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 4.611036e-01 | 0.336 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 4.611036e-01 | 0.336 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 4.611036e-01 | 0.336 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 3.791296e-01 | 0.421 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 3.226333e-01 | 0.491 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 4.396957e-01 | 0.357 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 4.246261e-01 | 0.372 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 4.607961e-01 | 0.336 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 4.856243e-01 | 0.314 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 4.856243e-01 | 0.314 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 4.258643e-01 | 0.371 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 4.415255e-01 | 0.355 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.597090e-01 | 0.338 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 4.816136e-01 | 0.317 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.781139e-01 | 0.320 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.781139e-01 | 0.320 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 4.781139e-01 | 0.320 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.781139e-01 | 0.320 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 4.259925e-01 | 0.371 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 4.394302e-01 | 0.357 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 4.552771e-01 | 0.342 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 4.537264e-01 | 0.343 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 4.915203e-01 | 0.308 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 4.837977e-01 | 0.315 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 4.791770e-01 | 0.320 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 3.481323e-01 | 0.458 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.607961e-01 | 0.336 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 4.805440e-01 | 0.318 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 3.588320e-01 | 0.445 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 4.335396e-01 | 0.363 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 4.355996e-01 | 0.361 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 3.091007e-01 | 0.510 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.228053e-01 | 0.491 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 2.695049e-01 | 0.569 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 3.278653e-01 | 0.484 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 4.360901e-01 | 0.360 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 3.751920e-01 | 0.426 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.725303e-01 | 0.429 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 3.238067e-01 | 0.490 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.498152e-01 | 0.602 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 2.761024e-01 | 0.559 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 3.140700e-01 | 0.503 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 3.326407e-01 | 0.478 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 4.856243e-01 | 0.314 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.575140e-01 | 0.589 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 2.527482e-01 | 0.597 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 2.527482e-01 | 0.597 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 3.587623e-01 | 0.445 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 3.930317e-01 | 0.406 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 4.264438e-01 | 0.370 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 3.848697e-01 | 0.415 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 3.846205e-01 | 0.415 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 4.837977e-01 | 0.315 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 3.656723e-01 | 0.437 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 3.796488e-01 | 0.421 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 2.802620e-01 | 0.552 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 4.925119e-01 | 0.308 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 4.264438e-01 | 0.370 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 2.566282e-01 | 0.591 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 4.588648e-01 | 0.338 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 3.751920e-01 | 0.426 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 3.534783e-01 | 0.452 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 3.250170e-01 | 0.488 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 3.491386e-01 | 0.457 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 4.607473e-01 | 0.337 | 1 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 3.003056e-01 | 0.522 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 4.901926e-01 | 0.310 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 3.930317e-01 | 0.406 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 4.925119e-01 | 0.308 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 4.925119e-01 | 0.308 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 4.415255e-01 | 0.355 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.539634e-01 | 0.595 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 2.886186e-01 | 0.540 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 3.195410e-01 | 0.495 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 4.035389e-01 | 0.394 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 2.889943e-01 | 0.539 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 3.751920e-01 | 0.426 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 2.731130e-01 | 0.564 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 3.278653e-01 | 0.484 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 4.360901e-01 | 0.360 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 3.338991e-01 | 0.476 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 4.360901e-01 | 0.360 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 3.543005e-01 | 0.451 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 4.902937e-01 | 0.310 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 3.760493e-01 | 0.425 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 3.556506e-01 | 0.449 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 4.264438e-01 | 0.370 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 4.266454e-01 | 0.370 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 3.238067e-01 | 0.490 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 2.894164e-01 | 0.538 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 3.051160e-01 | 0.516 | 1 | 1 |
| DNA Repair | R-HSA-73894 | 3.799224e-01 | 0.420 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 3.848697e-01 | 0.415 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.635670e-01 | 0.439 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 4.805440e-01 | 0.318 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.810900e-01 | 0.419 | 1 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.522272e-01 | 0.598 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.522272e-01 | 0.598 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 3.212847e-01 | 0.493 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 3.212847e-01 | 0.493 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.212847e-01 | 0.493 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 3.839684e-01 | 0.416 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 2.883801e-01 | 0.540 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 3.238067e-01 | 0.490 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 4.408662e-01 | 0.356 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 3.587623e-01 | 0.445 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 4.925119e-01 | 0.308 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.467385e-01 | 0.460 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 3.656723e-01 | 0.437 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 3.635670e-01 | 0.439 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 4.856243e-01 | 0.314 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 4.781139e-01 | 0.320 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 4.142318e-01 | 0.383 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 4.223857e-01 | 0.374 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 3.326407e-01 | 0.478 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 4.036522e-01 | 0.394 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 4.809170e-01 | 0.318 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 3.587623e-01 | 0.445 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 3.681295e-01 | 0.434 | 1 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 3.739322e-01 | 0.427 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 3.681295e-01 | 0.434 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 3.681295e-01 | 0.434 | 1 | 0 |
| HCMV Late Events | R-HSA-9610379 | 3.402857e-01 | 0.468 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.566578e-01 | 0.448 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 3.064091e-01 | 0.514 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 4.816136e-01 | 0.317 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 3.921592e-01 | 0.407 | 1 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 4.408662e-01 | 0.356 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.802620e-01 | 0.552 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 2.463634e-01 | 0.608 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 2.463634e-01 | 0.608 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 3.587623e-01 | 0.445 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.925119e-01 | 0.308 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 4.749984e-01 | 0.323 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 3.610602e-01 | 0.442 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 4.035298e-01 | 0.394 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 4.588648e-01 | 0.338 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 3.610602e-01 | 0.442 | 1 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 4.583251e-01 | 0.339 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 4.366094e-01 | 0.360 | 1 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 4.138469e-01 | 0.383 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 4.011332e-01 | 0.397 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 3.060691e-01 | 0.514 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 3.060691e-01 | 0.514 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 4.223857e-01 | 0.374 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.522272e-01 | 0.598 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.839684e-01 | 0.416 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 4.408662e-01 | 0.356 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 2.721660e-01 | 0.565 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 3.947164e-01 | 0.404 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 4.649072e-01 | 0.333 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 4.258643e-01 | 0.371 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 4.360901e-01 | 0.360 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 3.906420e-01 | 0.408 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 4.749984e-01 | 0.323 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.930317e-01 | 0.406 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 4.027879e-01 | 0.395 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 2.894928e-01 | 0.538 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 4.106524e-01 | 0.387 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 3.848697e-01 | 0.415 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 2.886186e-01 | 0.540 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 3.180812e-01 | 0.497 | 1 | 1 |
| Diseases of DNA repair | R-HSA-9675135 | 4.246261e-01 | 0.372 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 2.527482e-01 | 0.597 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 3.839684e-01 | 0.416 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 3.238067e-01 | 0.490 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.587623e-01 | 0.445 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 3.064091e-01 | 0.514 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 2.886186e-01 | 0.540 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 4.264438e-01 | 0.370 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 2.800957e-01 | 0.553 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 4.611036e-01 | 0.336 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 4.583251e-01 | 0.339 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 4.035389e-01 | 0.394 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 4.183595e-01 | 0.378 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 3.463206e-01 | 0.461 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 3.569925e-01 | 0.447 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.212847e-01 | 0.493 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.238067e-01 | 0.490 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.802620e-01 | 0.552 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 4.901926e-01 | 0.310 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.894928e-01 | 0.538 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 3.587623e-01 | 0.445 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.673395e-01 | 0.573 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 4.901926e-01 | 0.310 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.930317e-01 | 0.406 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 4.925119e-01 | 0.308 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 4.588648e-01 | 0.338 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 3.238067e-01 | 0.490 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 4.925119e-01 | 0.308 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.258643e-01 | 0.371 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 3.587623e-01 | 0.445 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 4.106524e-01 | 0.387 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 2.935699e-01 | 0.532 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 4.983841e-01 | 0.302 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 5.027083e-01 | 0.299 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 5.095933e-01 | 0.293 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 5.095933e-01 | 0.293 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 5.095933e-01 | 0.293 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 5.095933e-01 | 0.293 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 5.120932e-01 | 0.291 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 5.142500e-01 | 0.289 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 5.142500e-01 | 0.289 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 5.142500e-01 | 0.289 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.142500e-01 | 0.289 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 5.142500e-01 | 0.289 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 5.174885e-01 | 0.286 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 5.179054e-01 | 0.286 | 1 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 5.179054e-01 | 0.286 | 1 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 5.182487e-01 | 0.285 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 5.203527e-01 | 0.284 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 5.203527e-01 | 0.284 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 5.203527e-01 | 0.284 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 5.203527e-01 | 0.284 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 5.203527e-01 | 0.284 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 5.203527e-01 | 0.284 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 5.222343e-01 | 0.282 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 5.222343e-01 | 0.282 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 5.224648e-01 | 0.282 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 5.245493e-01 | 0.280 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 5.245557e-01 | 0.280 | 1 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 5.245557e-01 | 0.280 | 1 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 5.329609e-01 | 0.273 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 5.329609e-01 | 0.273 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 5.329609e-01 | 0.273 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 5.329609e-01 | 0.273 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 5.329609e-01 | 0.273 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 5.329609e-01 | 0.273 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 5.393899e-01 | 0.268 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.393899e-01 | 0.268 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.393899e-01 | 0.268 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 5.393899e-01 | 0.268 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 5.393899e-01 | 0.268 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.393899e-01 | 0.268 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.393899e-01 | 0.268 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 5.393899e-01 | 0.268 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 5.393899e-01 | 0.268 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 5.393899e-01 | 0.268 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 5.393899e-01 | 0.268 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 5.393899e-01 | 0.268 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 5.393899e-01 | 0.268 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 5.393899e-01 | 0.268 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 5.393899e-01 | 0.268 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 5.393899e-01 | 0.268 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 5.393899e-01 | 0.268 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 5.393899e-01 | 0.268 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 5.393899e-01 | 0.268 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 5.393899e-01 | 0.268 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 5.393899e-01 | 0.268 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 5.399510e-01 | 0.268 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 5.419658e-01 | 0.266 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 5.419658e-01 | 0.266 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 5.422446e-01 | 0.266 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 5.492936e-01 | 0.260 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 5.492936e-01 | 0.260 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 5.492936e-01 | 0.260 | 1 | 1 |
| p75NTR signals via NF-kB | R-HSA-193639 | 5.492936e-01 | 0.260 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 5.492936e-01 | 0.260 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 5.492936e-01 | 0.260 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 5.492936e-01 | 0.260 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 5.492936e-01 | 0.260 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 5.492936e-01 | 0.260 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 5.493044e-01 | 0.260 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 5.493044e-01 | 0.260 | 0 | 0 |
| Immune System | R-HSA-168256 | 5.523654e-01 | 0.258 | 1 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 5.556860e-01 | 0.255 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 5.556860e-01 | 0.255 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 5.556860e-01 | 0.255 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 5.562298e-01 | 0.255 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 5.565594e-01 | 0.254 | 1 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 5.565594e-01 | 0.254 | 1 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 5.572876e-01 | 0.254 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 5.612168e-01 | 0.251 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 5.612707e-01 | 0.251 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 5.612707e-01 | 0.251 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 5.612707e-01 | 0.251 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 5.612707e-01 | 0.251 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 5.613164e-01 | 0.251 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 5.623284e-01 | 0.250 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 5.663664e-01 | 0.247 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 5.715103e-01 | 0.243 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 5.757371e-01 | 0.240 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 5.769832e-01 | 0.239 | 1 | 1 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 5.769832e-01 | 0.239 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 5.769832e-01 | 0.239 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 5.769832e-01 | 0.239 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 5.769832e-01 | 0.239 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 5.769832e-01 | 0.239 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 5.769832e-01 | 0.239 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 5.769832e-01 | 0.239 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 5.777354e-01 | 0.238 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.777354e-01 | 0.238 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 5.777354e-01 | 0.238 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 5.801235e-01 | 0.236 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 5.801235e-01 | 0.236 | 1 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 5.801235e-01 | 0.236 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.819403e-01 | 0.235 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 5.819403e-01 | 0.235 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.819403e-01 | 0.235 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.819403e-01 | 0.235 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.819403e-01 | 0.235 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 5.819403e-01 | 0.235 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 5.819403e-01 | 0.235 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 5.819403e-01 | 0.235 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.819403e-01 | 0.235 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 5.819403e-01 | 0.235 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 5.819403e-01 | 0.235 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 5.830915e-01 | 0.234 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 5.830915e-01 | 0.234 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 5.830915e-01 | 0.234 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 5.830915e-01 | 0.234 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 5.830915e-01 | 0.234 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 5.830915e-01 | 0.234 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 5.862707e-01 | 0.232 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 5.874637e-01 | 0.231 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 5.927357e-01 | 0.227 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 5.979298e-01 | 0.223 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 5.979298e-01 | 0.223 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 5.979298e-01 | 0.223 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 5.985028e-01 | 0.223 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 5.985028e-01 | 0.223 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 5.985028e-01 | 0.223 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 5.990413e-01 | 0.223 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 5.990831e-01 | 0.223 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 5.990831e-01 | 0.223 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 5.990831e-01 | 0.223 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 5.990831e-01 | 0.223 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 5.994623e-01 | 0.222 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 5.994623e-01 | 0.222 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 6.032593e-01 | 0.219 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 6.034056e-01 | 0.219 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 6.034056e-01 | 0.219 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 6.034056e-01 | 0.219 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 6.034056e-01 | 0.219 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 6.034056e-01 | 0.219 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 6.092628e-01 | 0.215 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 6.154639e-01 | 0.211 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 6.163905e-01 | 0.210 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 6.181852e-01 | 0.209 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 6.198690e-01 | 0.208 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 6.205622e-01 | 0.207 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 6.205622e-01 | 0.207 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 6.205622e-01 | 0.207 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.205622e-01 | 0.207 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 6.205622e-01 | 0.207 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 6.205622e-01 | 0.207 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 6.205622e-01 | 0.207 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 6.205622e-01 | 0.207 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 6.205622e-01 | 0.207 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 6.205622e-01 | 0.207 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.205622e-01 | 0.207 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 6.205622e-01 | 0.207 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 6.205622e-01 | 0.207 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.205622e-01 | 0.207 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 6.205622e-01 | 0.207 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 6.205622e-01 | 0.207 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 6.205622e-01 | 0.207 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 6.205622e-01 | 0.207 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 6.205622e-01 | 0.207 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 6.205622e-01 | 0.207 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 6.285587e-01 | 0.202 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 6.285587e-01 | 0.202 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 6.285587e-01 | 0.202 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 6.285587e-01 | 0.202 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 6.285587e-01 | 0.202 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 6.285587e-01 | 0.202 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 6.285587e-01 | 0.202 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 6.285587e-01 | 0.202 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 6.300174e-01 | 0.201 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.300611e-01 | 0.201 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 6.305882e-01 | 0.200 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 6.396014e-01 | 0.194 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 6.396014e-01 | 0.194 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 6.396014e-01 | 0.194 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 6.396014e-01 | 0.194 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.410061e-01 | 0.193 | 1 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 6.430073e-01 | 0.192 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 6.430073e-01 | 0.192 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 6.463103e-01 | 0.190 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 6.506362e-01 | 0.187 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 6.506362e-01 | 0.187 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 6.524515e-01 | 0.185 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 6.524515e-01 | 0.185 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.556181e-01 | 0.183 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.556181e-01 | 0.183 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.556181e-01 | 0.183 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 6.556181e-01 | 0.183 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 6.556181e-01 | 0.183 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 6.556181e-01 | 0.183 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 6.556181e-01 | 0.183 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 6.556181e-01 | 0.183 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 6.556181e-01 | 0.183 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 6.556181e-01 | 0.183 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 6.556181e-01 | 0.183 | 0 | 0 |
| Fructose biosynthesis | R-HSA-5652227 | 6.556181e-01 | 0.183 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 6.556181e-01 | 0.183 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 6.556181e-01 | 0.183 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 6.556181e-01 | 0.183 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 6.556181e-01 | 0.183 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 6.556181e-01 | 0.183 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 6.556181e-01 | 0.183 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 6.556181e-01 | 0.183 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 6.556181e-01 | 0.183 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 6.556181e-01 | 0.183 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 6.556181e-01 | 0.183 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 6.576983e-01 | 0.182 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 6.576983e-01 | 0.182 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 6.587504e-01 | 0.181 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 6.587504e-01 | 0.181 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 6.587504e-01 | 0.181 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 6.664255e-01 | 0.176 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 6.669745e-01 | 0.176 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 6.669745e-01 | 0.176 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 6.669745e-01 | 0.176 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 6.669745e-01 | 0.176 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 6.669745e-01 | 0.176 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 6.693806e-01 | 0.174 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 6.710255e-01 | 0.173 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 6.751021e-01 | 0.171 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.751021e-01 | 0.171 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 6.751021e-01 | 0.171 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 6.755523e-01 | 0.170 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 6.771532e-01 | 0.169 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 6.803357e-01 | 0.167 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 6.840173e-01 | 0.165 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 6.855540e-01 | 0.164 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 6.855540e-01 | 0.164 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.874371e-01 | 0.163 | 1 | 1 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.874371e-01 | 0.163 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 6.874371e-01 | 0.163 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.874371e-01 | 0.163 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 6.874371e-01 | 0.163 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 6.874371e-01 | 0.163 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 6.874371e-01 | 0.163 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.874371e-01 | 0.163 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 6.874371e-01 | 0.163 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 6.874371e-01 | 0.163 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 6.874371e-01 | 0.163 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 6.895553e-01 | 0.161 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 6.922136e-01 | 0.160 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 6.948109e-01 | 0.158 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 6.965360e-01 | 0.157 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 6.965360e-01 | 0.157 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 6.965360e-01 | 0.157 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 6.980533e-01 | 0.156 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 6.980533e-01 | 0.156 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 7.117279e-01 | 0.148 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 7.117279e-01 | 0.148 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 7.127900e-01 | 0.147 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 7.127900e-01 | 0.147 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 7.163180e-01 | 0.145 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 7.163180e-01 | 0.145 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 7.163180e-01 | 0.145 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 7.163180e-01 | 0.145 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 7.163180e-01 | 0.145 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 7.163180e-01 | 0.145 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 7.163180e-01 | 0.145 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 7.163180e-01 | 0.145 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 7.163180e-01 | 0.145 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 7.167848e-01 | 0.145 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 7.167848e-01 | 0.145 | 1 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 7.269925e-01 | 0.138 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 7.269925e-01 | 0.138 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 7.274151e-01 | 0.138 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 7.279122e-01 | 0.138 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.279122e-01 | 0.138 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 7.279122e-01 | 0.138 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 7.358843e-01 | 0.133 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 7.358843e-01 | 0.133 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 7.358843e-01 | 0.133 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 7.368094e-01 | 0.133 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 7.406640e-01 | 0.130 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 7.413808e-01 | 0.130 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 7.425318e-01 | 0.129 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 7.425318e-01 | 0.129 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.425318e-01 | 0.129 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.425318e-01 | 0.129 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 7.425318e-01 | 0.129 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 7.425318e-01 | 0.129 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.425318e-01 | 0.129 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 7.425318e-01 | 0.129 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 7.425318e-01 | 0.129 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 7.425318e-01 | 0.129 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 7.425318e-01 | 0.129 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.425318e-01 | 0.129 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 7.433747e-01 | 0.129 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 7.433747e-01 | 0.129 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 7.538094e-01 | 0.123 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 7.538739e-01 | 0.123 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 7.538739e-01 | 0.123 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 7.538739e-01 | 0.123 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 7.538739e-01 | 0.123 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 7.538739e-01 | 0.123 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 7.538739e-01 | 0.123 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 7.538739e-01 | 0.123 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 7.581283e-01 | 0.120 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 7.581283e-01 | 0.120 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 7.581283e-01 | 0.120 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 7.581283e-01 | 0.120 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 7.581283e-01 | 0.120 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 7.653356e-01 | 0.116 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 7.663247e-01 | 0.116 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 7.663247e-01 | 0.116 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.663247e-01 | 0.116 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 7.663247e-01 | 0.116 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 7.663247e-01 | 0.116 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 7.663247e-01 | 0.116 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 7.663247e-01 | 0.116 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 7.663247e-01 | 0.116 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.663247e-01 | 0.116 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 7.663247e-01 | 0.116 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 7.680766e-01 | 0.115 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 7.707958e-01 | 0.113 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.707958e-01 | 0.113 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 7.721885e-01 | 0.112 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 7.746175e-01 | 0.111 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 7.801527e-01 | 0.108 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 7.855721e-01 | 0.105 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 7.865502e-01 | 0.104 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 7.866935e-01 | 0.104 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 7.866935e-01 | 0.104 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 7.866935e-01 | 0.104 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 7.879201e-01 | 0.104 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 7.879201e-01 | 0.104 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 7.879201e-01 | 0.104 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 7.879201e-01 | 0.104 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 7.879201e-01 | 0.104 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.879201e-01 | 0.104 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 7.879201e-01 | 0.104 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 7.879201e-01 | 0.104 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 7.879201e-01 | 0.104 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 7.879201e-01 | 0.104 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 7.930944e-01 | 0.101 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 7.948744e-01 | 0.100 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.982975e-01 | 0.098 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.982975e-01 | 0.098 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 7.982975e-01 | 0.098 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 8.012776e-01 | 0.096 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 8.012776e-01 | 0.096 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 8.016118e-01 | 0.096 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 8.016118e-01 | 0.096 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.016118e-01 | 0.096 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 8.016118e-01 | 0.096 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 8.075210e-01 | 0.093 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 8.075210e-01 | 0.093 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 8.075210e-01 | 0.093 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.075210e-01 | 0.093 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 8.075210e-01 | 0.093 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 8.075210e-01 | 0.093 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 8.075210e-01 | 0.093 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 8.075210e-01 | 0.093 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.075210e-01 | 0.093 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 8.110925e-01 | 0.091 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 8.119133e-01 | 0.090 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 8.131756e-01 | 0.090 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.155959e-01 | 0.089 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.155959e-01 | 0.089 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 8.162168e-01 | 0.088 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 8.217600e-01 | 0.085 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 8.218527e-01 | 0.085 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 8.218527e-01 | 0.085 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 8.218527e-01 | 0.085 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 8.218527e-01 | 0.085 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 8.220785e-01 | 0.085 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 8.253113e-01 | 0.083 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 8.253113e-01 | 0.083 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 8.253113e-01 | 0.083 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 8.253113e-01 | 0.083 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 8.253113e-01 | 0.083 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 8.253113e-01 | 0.083 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 8.253113e-01 | 0.083 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.253113e-01 | 0.083 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.253113e-01 | 0.083 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 8.253113e-01 | 0.083 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 8.253388e-01 | 0.083 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 8.263147e-01 | 0.083 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 8.286910e-01 | 0.082 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 8.286910e-01 | 0.082 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 8.286910e-01 | 0.082 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 8.286910e-01 | 0.082 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 8.286910e-01 | 0.082 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 8.286910e-01 | 0.082 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 8.317854e-01 | 0.080 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.317854e-01 | 0.080 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 8.327240e-01 | 0.079 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 8.327240e-01 | 0.079 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 8.327240e-01 | 0.079 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 8.337543e-01 | 0.079 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 8.374807e-01 | 0.077 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 8.374807e-01 | 0.077 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 8.391385e-01 | 0.076 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 8.409418e-01 | 0.075 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 8.409418e-01 | 0.075 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 8.409418e-01 | 0.075 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 8.410468e-01 | 0.075 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.410468e-01 | 0.075 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 8.414583e-01 | 0.075 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 8.414583e-01 | 0.075 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 8.414583e-01 | 0.075 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.414583e-01 | 0.075 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.414583e-01 | 0.075 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 8.414583e-01 | 0.075 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 8.414583e-01 | 0.075 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 8.414583e-01 | 0.075 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 8.414583e-01 | 0.075 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 8.414583e-01 | 0.075 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 8.430195e-01 | 0.074 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 8.430195e-01 | 0.074 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 8.430195e-01 | 0.074 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 8.430195e-01 | 0.074 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 8.430195e-01 | 0.074 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 8.450776e-01 | 0.073 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 8.497437e-01 | 0.071 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 8.523927e-01 | 0.069 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 8.527610e-01 | 0.069 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 8.527610e-01 | 0.069 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.527610e-01 | 0.069 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 8.527610e-01 | 0.069 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 8.527610e-01 | 0.069 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.561136e-01 | 0.067 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.561136e-01 | 0.067 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.561136e-01 | 0.067 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 8.561136e-01 | 0.067 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 8.561136e-01 | 0.067 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 8.561136e-01 | 0.067 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 8.561136e-01 | 0.067 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 8.561136e-01 | 0.067 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 8.561136e-01 | 0.067 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.577464e-01 | 0.067 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 8.619706e-01 | 0.065 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 8.619706e-01 | 0.065 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 8.621564e-01 | 0.064 | 1 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 8.630866e-01 | 0.064 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 8.664893e-01 | 0.062 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 8.694150e-01 | 0.061 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.694150e-01 | 0.061 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 8.694150e-01 | 0.061 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.694150e-01 | 0.061 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 8.694150e-01 | 0.061 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 8.706700e-01 | 0.060 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 8.706700e-01 | 0.060 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 8.730657e-01 | 0.059 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.730657e-01 | 0.059 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.730657e-01 | 0.059 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 8.730657e-01 | 0.059 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 8.738117e-01 | 0.059 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 8.739044e-01 | 0.059 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 8.753324e-01 | 0.058 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 8.788810e-01 | 0.056 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 8.788810e-01 | 0.056 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 8.811388e-01 | 0.055 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 8.811403e-01 | 0.055 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 8.811403e-01 | 0.055 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 8.814875e-01 | 0.055 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.814875e-01 | 0.055 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 8.814875e-01 | 0.055 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.814875e-01 | 0.055 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.814875e-01 | 0.055 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.814875e-01 | 0.055 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 8.814875e-01 | 0.055 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 8.823707e-01 | 0.054 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 8.857427e-01 | 0.053 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 8.862219e-01 | 0.052 | 1 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 8.866252e-01 | 0.052 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 8.866252e-01 | 0.052 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 8.866252e-01 | 0.052 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 8.866252e-01 | 0.052 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 8.866252e-01 | 0.052 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 8.880126e-01 | 0.052 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 8.910063e-01 | 0.050 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 8.910410e-01 | 0.050 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 8.924446e-01 | 0.049 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 8.924446e-01 | 0.049 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 8.924446e-01 | 0.049 | 0 | 0 |
| PKA activation | R-HSA-163615 | 8.924446e-01 | 0.049 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 8.924446e-01 | 0.049 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 8.924446e-01 | 0.049 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 8.924446e-01 | 0.049 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 8.924446e-01 | 0.049 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 8.924446e-01 | 0.049 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 8.938707e-01 | 0.049 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 8.939238e-01 | 0.049 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 8.939238e-01 | 0.049 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.968308e-01 | 0.047 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 8.975786e-01 | 0.047 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 8.976999e-01 | 0.047 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 8.982929e-01 | 0.047 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 8.991142e-01 | 0.046 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 8.991142e-01 | 0.046 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 8.991142e-01 | 0.046 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 8.991142e-01 | 0.046 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 9.007212e-01 | 0.045 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 9.007212e-01 | 0.045 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.020373e-01 | 0.045 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.021515e-01 | 0.045 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 9.023892e-01 | 0.045 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 9.023892e-01 | 0.045 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 9.023892e-01 | 0.045 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.023892e-01 | 0.045 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 9.023892e-01 | 0.045 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 9.023892e-01 | 0.045 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.023892e-01 | 0.045 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 9.023892e-01 | 0.045 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.023892e-01 | 0.045 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 9.023892e-01 | 0.045 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 9.023892e-01 | 0.045 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 9.023892e-01 | 0.045 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.023892e-01 | 0.045 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 9.065848e-01 | 0.043 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.065848e-01 | 0.043 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.066268e-01 | 0.043 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 9.066268e-01 | 0.043 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.066268e-01 | 0.043 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 9.066268e-01 | 0.043 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.072667e-01 | 0.042 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 9.114148e-01 | 0.040 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 9.114148e-01 | 0.040 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 9.114148e-01 | 0.040 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 9.114148e-01 | 0.040 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 9.114148e-01 | 0.040 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.114148e-01 | 0.040 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 9.114148e-01 | 0.040 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.114148e-01 | 0.040 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.114148e-01 | 0.040 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 9.114148e-01 | 0.040 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.114148e-01 | 0.040 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.118385e-01 | 0.040 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 9.157567e-01 | 0.038 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 9.173973e-01 | 0.037 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 9.173973e-01 | 0.037 | 1 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.190702e-01 | 0.037 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 9.196064e-01 | 0.036 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 9.196064e-01 | 0.036 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 9.196064e-01 | 0.036 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 9.196064e-01 | 0.036 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 9.196064e-01 | 0.036 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 9.196064e-01 | 0.036 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 9.196064e-01 | 0.036 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.201065e-01 | 0.036 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.201065e-01 | 0.036 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 9.223721e-01 | 0.035 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.235129e-01 | 0.035 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.244425e-01 | 0.034 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.244425e-01 | 0.034 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.261382e-01 | 0.033 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 9.270410e-01 | 0.033 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 9.270410e-01 | 0.033 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 9.270410e-01 | 0.033 | 1 | 1 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 9.270410e-01 | 0.033 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.270410e-01 | 0.033 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.270410e-01 | 0.033 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 9.270410e-01 | 0.033 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 9.272805e-01 | 0.033 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.289122e-01 | 0.032 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.294860e-01 | 0.032 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.294860e-01 | 0.032 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.294860e-01 | 0.032 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.313342e-01 | 0.031 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.314851e-01 | 0.031 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 9.315216e-01 | 0.031 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.315216e-01 | 0.031 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.317381e-01 | 0.031 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 9.317381e-01 | 0.031 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.337884e-01 | 0.030 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.337884e-01 | 0.030 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.337884e-01 | 0.030 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.363013e-01 | 0.029 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.386559e-01 | 0.027 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.390011e-01 | 0.027 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.399121e-01 | 0.027 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 9.399121e-01 | 0.027 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.399121e-01 | 0.027 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.399121e-01 | 0.027 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.399121e-01 | 0.027 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.399121e-01 | 0.027 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.409111e-01 | 0.026 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.434243e-01 | 0.025 | 0 | 0 |
| Translation | R-HSA-72766 | 9.440733e-01 | 0.025 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 9.446334e-01 | 0.025 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.454698e-01 | 0.024 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.454698e-01 | 0.024 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 9.454698e-01 | 0.024 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.454698e-01 | 0.024 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 9.461073e-01 | 0.024 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.462217e-01 | 0.024 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 9.467113e-01 | 0.024 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.503617e-01 | 0.022 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.503617e-01 | 0.022 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.505138e-01 | 0.022 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.505138e-01 | 0.022 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.505138e-01 | 0.022 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 9.505138e-01 | 0.022 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.505138e-01 | 0.022 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.505138e-01 | 0.022 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 9.505138e-01 | 0.022 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.505138e-01 | 0.022 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.505138e-01 | 0.022 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.505138e-01 | 0.022 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.505138e-01 | 0.022 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 9.505138e-01 | 0.022 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.505138e-01 | 0.022 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 9.505138e-01 | 0.022 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.506784e-01 | 0.022 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 9.534079e-01 | 0.021 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.538242e-01 | 0.021 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.541963e-01 | 0.020 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.550915e-01 | 0.020 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 9.550915e-01 | 0.020 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 9.550915e-01 | 0.020 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.550915e-01 | 0.020 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 9.550915e-01 | 0.020 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.561554e-01 | 0.019 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.569667e-01 | 0.019 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.569667e-01 | 0.019 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.591336e-01 | 0.018 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.591336e-01 | 0.018 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.591336e-01 | 0.018 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 9.592459e-01 | 0.018 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 9.592459e-01 | 0.018 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 9.592459e-01 | 0.018 | 0 | 0 |
| Cobalamin (Cbl) metabolism | R-HSA-9759218 | 9.592459e-01 | 0.018 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 9.592459e-01 | 0.018 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 9.592459e-01 | 0.018 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 9.592459e-01 | 0.018 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.592459e-01 | 0.018 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.592459e-01 | 0.018 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.592459e-01 | 0.018 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 9.599525e-01 | 0.018 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 9.599525e-01 | 0.018 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 9.599525e-01 | 0.018 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 9.599525e-01 | 0.018 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.599525e-01 | 0.018 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 9.599525e-01 | 0.018 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.599525e-01 | 0.018 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.618870e-01 | 0.017 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.630163e-01 | 0.016 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 9.630163e-01 | 0.016 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.630163e-01 | 0.016 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 9.640719e-01 | 0.016 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 9.640719e-01 | 0.016 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.642021e-01 | 0.016 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.653495e-01 | 0.015 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 9.659718e-01 | 0.015 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.661869e-01 | 0.015 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 9.664381e-01 | 0.015 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.664381e-01 | 0.015 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.664381e-01 | 0.015 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.664381e-01 | 0.015 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 9.664381e-01 | 0.015 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 9.664381e-01 | 0.015 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.664381e-01 | 0.015 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.668829e-01 | 0.015 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.668829e-01 | 0.015 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.668829e-01 | 0.015 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.670531e-01 | 0.015 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.670531e-01 | 0.015 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.670531e-01 | 0.015 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.677834e-01 | 0.014 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 9.686809e-01 | 0.014 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.687998e-01 | 0.014 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.695434e-01 | 0.013 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 9.695434e-01 | 0.013 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.695434e-01 | 0.013 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.695434e-01 | 0.013 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.700552e-01 | 0.013 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 9.723616e-01 | 0.012 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.723616e-01 | 0.012 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.724913e-01 | 0.012 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.741015e-01 | 0.011 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.741015e-01 | 0.011 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.747153e-01 | 0.011 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.747283e-01 | 0.011 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.749192e-01 | 0.011 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 9.749192e-01 | 0.011 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.759946e-01 | 0.011 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 9.772402e-01 | 0.010 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 9.772402e-01 | 0.010 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.772402e-01 | 0.010 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.772402e-01 | 0.010 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.780421e-01 | 0.010 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 9.780986e-01 | 0.010 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.793466e-01 | 0.009 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 9.793466e-01 | 0.009 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.812581e-01 | 0.008 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.812581e-01 | 0.008 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.812581e-01 | 0.008 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.812581e-01 | 0.008 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.812581e-01 | 0.008 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.818619e-01 | 0.008 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.829929e-01 | 0.007 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.829929e-01 | 0.007 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.829929e-01 | 0.007 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.829929e-01 | 0.007 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.829929e-01 | 0.007 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.839671e-01 | 0.007 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.841124e-01 | 0.007 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.842555e-01 | 0.007 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 9.845671e-01 | 0.007 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.845671e-01 | 0.007 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.845671e-01 | 0.007 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.846026e-01 | 0.007 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.846823e-01 | 0.007 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.855190e-01 | 0.006 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.859494e-01 | 0.006 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.859957e-01 | 0.006 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 9.859957e-01 | 0.006 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.859957e-01 | 0.006 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.862846e-01 | 0.006 | 0 | 0 |
| Depurination | R-HSA-73927 | 9.872922e-01 | 0.006 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.872922e-01 | 0.006 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 9.872922e-01 | 0.006 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.872922e-01 | 0.006 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.877567e-01 | 0.005 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.881026e-01 | 0.005 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.884687e-01 | 0.005 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.884687e-01 | 0.005 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.894430e-01 | 0.005 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.895349e-01 | 0.005 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.895349e-01 | 0.005 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.895349e-01 | 0.005 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.895363e-01 | 0.005 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.895363e-01 | 0.005 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.895363e-01 | 0.005 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.903090e-01 | 0.004 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 9.903331e-01 | 0.004 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.904946e-01 | 0.004 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.904946e-01 | 0.004 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.904946e-01 | 0.004 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.905052e-01 | 0.004 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.913844e-01 | 0.004 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.921822e-01 | 0.003 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.921822e-01 | 0.003 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.921822e-01 | 0.003 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.921822e-01 | 0.003 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.927131e-01 | 0.003 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.928884e-01 | 0.003 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.929062e-01 | 0.003 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.929062e-01 | 0.003 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.935632e-01 | 0.003 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.935632e-01 | 0.003 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.935632e-01 | 0.003 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.937097e-01 | 0.003 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.942009e-01 | 0.003 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.943731e-01 | 0.002 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.947635e-01 | 0.002 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.951913e-01 | 0.002 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.951913e-01 | 0.002 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.954328e-01 | 0.002 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.955894e-01 | 0.002 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.956367e-01 | 0.002 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.959530e-01 | 0.002 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.959530e-01 | 0.002 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.959530e-01 | 0.002 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.962052e-01 | 0.002 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.962052e-01 | 0.002 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.967406e-01 | 0.001 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.969427e-01 | 0.001 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.970101e-01 | 0.001 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.971843e-01 | 0.001 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.971843e-01 | 0.001 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.973166e-01 | 0.001 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.974322e-01 | 0.001 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.975912e-01 | 0.001 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.977909e-01 | 0.001 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.977909e-01 | 0.001 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.977917e-01 | 0.001 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.981814e-01 | 0.001 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.982952e-01 | 0.001 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.982996e-01 | 0.001 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.984276e-01 | 0.001 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.985029e-01 | 0.001 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.986417e-01 | 0.001 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.986417e-01 | 0.001 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.989856e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.990452e-01 | 0.000 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.992424e-01 | 0.000 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.992505e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.993127e-01 | 0.000 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.993359e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.993764e-01 | 0.000 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 9.993764e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.994199e-01 | 0.000 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.994229e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.994867e-01 | 0.000 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.995038e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.995038e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.996167e-01 | 0.000 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.996521e-01 | 0.000 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.996523e-01 | 0.000 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.996535e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.996917e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.997645e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.997743e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.998027e-01 | 0.000 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.998698e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.998793e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.998863e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999169e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999256e-01 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.999446e-01 | 0.000 | 1 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.999513e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.999513e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.999597e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.999637e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999671e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999696e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999750e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999761e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999761e-01 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.999845e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999846e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999893e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999922e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999943e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999955e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999958e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.999964e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999964e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999982e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 9.999984e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999992e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.999994e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999994e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999995e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999997e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999997e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999999e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999999e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.000000e+00 | 0.000 | 1 | 1 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 1.000000e+00 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
