NLK
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| O00178 | S17 | Sugiyama | GTPBP1 | ____MATERsRsAMDsPVPAsMFAPEPssPGAARAAAAAAR |
| O00232 | T338 | Sugiyama | PSMD12 | STLVEDYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLKNRV |
| O14497 | S363 | Sugiyama | ARID1A BAF250 BAF250A C1orf4 OSA1 SMARCF1 | AAAAAAASGGAQQRsHHAPMsPGssGGGGQPLARtPQPssP |
| O14745 | S280 | Sugiyama | NHERF1 NHERF SLC9A3R1 | tNGEIQKENsREALAEAALEsPRPALVRsAssDtsEELNsQ |
| O14910 | S130 | Sugiyama | LIN7A MALS1 VELI1 | ELPKTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLK |
| O15067 | S1062 | Sugiyama | PFAS KIAA0361 | SYCLPPTFPKAsVPREPGGPsPRVAILREEGSNGDREMADA |
| O43423 | T101 | Sugiyama | ANP32CP PP32R1 | EKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCEV |
| O43707 | T612 | Sugiyama | ACTN4 | KEAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPK |
| O43707 | T615 | Sugiyama | ACTN4 | QRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPKRDH |
| O43707 | Y611 | Sugiyama | ACTN4 | HKEAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVP |
| O43852 | T65 | Sugiyama | CALU | FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD |
| O60784 | S462 | Sugiyama | TOM1 | EFDKFLEERAKAADRLPNLssPsAEGPPGPPsGPAPRKKTQ |
| O60784 | S473 | Sugiyama | TOM1 | AADRLPNLssPsAEGPPGPPsGPAPRKKTQEKDDDMLFAL_ |
| O75369 | T1620 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | PLsPyRIRAtQTGDASKCLAtGPGIASTVKTGEEVGFVVDA |
| O75828 | S56 | Sugiyama | CBR3 SDR21C2 | TARDVARGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF |
| O94776 | S435 | Sugiyama | MTA2 MTA1L1 PID | RGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFL |
| O94979 | S186 | Sugiyama | SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334 | QPPEDISCIAWNRQVQHILAsAsPsGRATVWDLRKNEPIIK |
| O94979 | S188 | Sugiyama | SEC31A KIAA0905 SEC31L1 HSPC275 HSPC334 | PEDISCIAWNRQVQHILAsAsPsGRATVWDLRKNEPIIKVS |
| O95067 | S392 | Sugiyama | CCNB2 | KLLKISMIPQLNSKAVKDLAsPLIGRs______________ |
| O95373 | T997 | Sugiyama | IPO7 RANBP7 | yQALTHGLNEEQRKQLQDIAtLADQRRAAHESKMIEKHGGY |
| O95433 | T20 | Sugiyama | AHSA1 C14orf3 HSPC322 | _MAKWGEGDPRWIVEERADAtNVNNWHWtERDASNWSTDKL |
| O95626 | T105 | Sugiyama | ANP32D PP32R2 | EKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCEV |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P00338 | T309 | Sugiyama | LDHA PIG19 | LSVPCILGQNGISDLVKVTLtsEEEARLKKsADtLWGIQKE |
| P00338 | T95 | Sugiyama | LDHA PIG19 | PKIVSGKDyNVTANsKLVIItAGARQQEGEsRLNLVQRNVN |
| P00558 | S393 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA |
| P00558 | T369 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | ARGTKALMDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKV |
| P00558 | T376 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG |
| P00558 | T394 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL |
| P00558 | Y161 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL |
| P03372 | S104 | PSP | ESR1 ESR NR3A1 | SEAAAFGSNGLGGFPPLNsVsPsPLMLLHPPPQLsPFLQPH |
| P03372 | S106 | PSP | ESR1 ESR NR3A1 | AAAFGSNGLGGFPPLNsVsPsPLMLLHPPPQLsPFLQPHGQ |
| P03372 | S118 | PSP | ESR1 ESR NR3A1 | PPLNsVsPsPLMLLHPPPQLsPFLQPHGQQVPYYLENEPSG |
| P03372 | S167 | PSP | ESR1 ESR NR3A1 | PAFYRPNsDNRRQGGRERLAsTNDKGSMAMESAKETRYCAV |
| P04040 | S515 | Sugiyama | CAT | ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________ |
| P04040 | T28 | Sugiyama | CAT | ASDQMQHWKEQRAAQKADVLttGAGNPVGDKLNVItVGPRG |
| P04040 | T511 | Sugiyama | CAT | SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T123 | Sugiyama | ALDOA ALDA | GVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGA |
| P04075 | T37 | Sugiyama | ALDOA ALDA | sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR |
| P04083 | S170 | Sugiyama | ANXA1 ANX1 LPC1 | RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE |
| P04181 | T39 | Sugiyama | OAT | HSSVASATSVATKKtVQGPPtSDDIFEREyKyGAHNyHPLP |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | T211 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05187 | S177 | Sugiyama | ALPP PLAP | RAKKAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADVP |
| P05787 | S291 | Sugiyama | KRT8 CYK8 | ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN |
| P06733 | S14 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA |
| P06733 | S272 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI |
| P06733 | T19 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T26 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA |
| P06733 | Y280 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T302 | Sugiyama | LDHB | YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07205 | S393 | Sugiyama | PGK2 PGKB | GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA |
| P07205 | T394 | Sugiyama | PGK2 PGKB | GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL |
| P07205 | Y161 | Sugiyama | PGK2 PGKB | KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL |
| P07237 | Y94 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK |
| P07437 | S172 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | ISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSVHQL |
| P07437 | T166 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | GMGTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT |
| P07437 | T55 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs |
| P07711 | T332 | Sugiyama | CTSL CTSL1 | VKMAKDRRNHCGIAsAAsyPtV___________________ |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07814 | S1350 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | YRRRLLsVNIRVRADLRDNysPGWKFNHWELKGVPIRLEVG |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07814 | S880 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | LKAQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPE |
| P07858 | S216 | Sugiyama | CTSB CPSB | PPCTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSE |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S391 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07942 | S658 | Sugiyama | LAMB1 | PTSSRCGNTIPDDDNQVVsLsPGSRYVVLPRPVCFEKGTNY |
| P08195 | S296 | Sugiyama | SLC3A2 MDU1 | DLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNYRGEN |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | S607 | Sugiyama | SLC3A2 MDU1 | ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP |
| P08195 | T401 | Sugiyama | SLC3A2 MDU1 | NSSDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQ |
| P08195 | T599 | Sugiyama | SLC3A2 MDU1 | QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH |
| P08238 | S383 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | T85 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI |
| P08238 | T89 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG |
| P08238 | T94 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSGtKAFM |
| P08758 | T10 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | ___________MAQVLRGtVtDFPGFDERADAEtLRKAMKG |
| P08758 | T111 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | yDAyELKHALKGAGTNEKVLtEIIAsRtPEELRAIKQVyEE |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P09382 | T58 | Sugiyama | LGALS1 | DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF |
| P09923 | S174 | Sugiyama | ALPI | RAKQAGKSVGVVTTTRVQHAsPAGtyAHtVNRNWysDADMP |
| P09972 | T125 | Sugiyama | ALDOC ALDC | VGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGADF |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0DPH7 | T334 | Sugiyama | TUBA3C TUBA2 | ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| P0DPH7 | T51 | Sugiyama | TUBA3C TUBA2 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P10809 | S70 | Sugiyama | HSPD1 HSP60 | AVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLKDKY |
| P10809 | T115 | Sugiyama | HSPD1 HSP60 | AKLVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISKGA |
| P10809 | T117 | Sugiyama | HSPD1 HSP60 | LVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISKGANP |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11142 | T37 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P11142 | T45 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11586 | S771 | Sugiyama | MTHFD1 MTHFC MTHFD | PVVVAVNAFKTDTEsELDLIsRLSREHGAFDAVKCTHWAEG |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P11831 | S101 | GPS6 | SRF | GDsEsGEEEELGAERRGLKRsLsEMEIGMVVGGPEASAAAT |
| P11831 | S103 | GPS6 | SRF | sEsGEEEELGAERRGLKRsLsEMEIGMVVGGPEASAAATGG |
| P12268 | S505 | Sugiyama | IMPDH2 IMPD2 | SGELKFEKRtssAQVEGGVHsLHsyEKRLF___________ |
| P12268 | S508 | Sugiyama | IMPDH2 IMPD2 | LKFEKRtssAQVEGGVHsLHsyEKRLF______________ |
| P12268 | Y509 | Sugiyama | IMPDH2 IMPD2 | KFEKRtssAQVEGGVHsLHsyEKRLF_______________ |
| P12277 | S129 | Sugiyama | CKB CKBB | DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG |
| P12277 | T35 | Sugiyama | CKB CKBB | PAEDEFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDD |
| P12277 | Y39 | Sugiyama | CKB CKBB | EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT |
| P13489 | S290 | Sugiyama | RNH1 PRI RNH | AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE |
| P13489 | T176 | Sugiyama | RNH1 PRI RNH | AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | S595 | Sugiyama | EEF2 EF2 | PVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGLAE |
| P13639 | T5 | Sugiyama | EEF2 EF2 | ________________MVNFtVDQIRAIMDKKANIRNMsVI |
| P13639 | T735 | Sugiyama | EEF2 EF2 | HRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCPEQV |
| P13639 | Y730 | Sugiyama | EEF2 EF2 | HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ |
| P13804 | S192 | Sugiyama | ETFA | sFDAAATsGGsASsEKAsStsPVEIsEWLDQKLTKSDRPEL |
| P13807 | S723 | Sugiyama | GYS1 GYS | TSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN______ |
| P13807 | S727 | Sugiyama | GYS1 GYS | KRNsVDtAtsssLstPsEPLsPtssLGEERN__________ |
| P13807 | T721 | Sugiyama | GYS1 GYS | sSTSGSKRNsVDtAtsssLstPsEPLsPtssLGEERN____ |
| P13929 | S14 | Sugiyama | ENO3 | _______MAMQKIFAREILDsRGNPtVEVDLHtAKGRFRAA |
| P13929 | T26 | Sugiyama | ENO3 | IFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGAstGIyEA |
| P14550 | S211 | Sugiyama | AKR1A1 ALDR1 ALR | LAQNELIAHCQARGLEVTAysPLGSSDRAWRDPDEPVLLEE |
| P14618 | S205 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD |
| P14618 | S37 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | QLHAAMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRs |
| P14618 | S55 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | IDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMNVARLN |
| P14618 | T195 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | yVDDGLISLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAA |
| P14618 | T50 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | T522 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | NRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMA |
| P14625 | T675 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | sGNMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIR |
| P14649 | T101 | Sugiyama | MYL6B MLC1SA | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDELKSRR |
| P14866 | S101 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | GAAGGGGGGENyDDPHKtPAsPVVHIRGLIDGVVEADLVEA |
| P15311 | T533 | Sugiyama | EZR VIL2 | NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15559 | S82 | Sugiyama | NQO1 DIA4 NMOR1 | DPANFQYPAESVLAYKEGHLsPDIVAEQKKLEAADLVIFQF |
| P16152 | S56 | Sugiyama | CBR1 CBR CRN SDR21C1 | TARDVTRGQAAVQQLQAEGLsPRFHQLDIDDLQsIRALRDF |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17066 | T228 | Sugiyama | HSPA6 HSP70B' | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P17066 | T47 | Sugiyama | HSPA6 HSP70B' | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P17706 | S298 | Sugiyama | PTPN2 PTPT | CIKGDSSIQKRWKELsKEDLsPAFDHsPNKIMtEKYNGNRI |
| P17706 | S304 | Sugiyama | PTPN2 PTPT | SIQKRWKELsKEDLsPAFDHsPNKIMtEKYNGNRIGLEEEK |
| P17812 | S210 | Sugiyama | CTPS1 CTPS | GEQKTKPTQNSVRELRGLGLsPDLVVCRCSNPLDTSVKEKI |
| P17812 | S575 | Sugiyama | CTPS1 CTPS | LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____ |
| P17812 | Y468 | Sugiyama | CTPS1 CTPS | MRLGKRRtLFQTKNsVMRKLyGDADyLEERHRHRFEVNPVW |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18669 | S152 | Sugiyama | PGAM1 PGAMA CDABP0006 | FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV |
| P18669 | S31 | Sugiyama | PGAM1 PGAMA CDABP0006 | HGEsAWNLENRFsGWyDADLsPAGHEEAKRGGQALRDAGyE |
| P18754 | S90 | Sugiyama | RCC1 CHC1 | VQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsVEGSEM |
| P19338 | Y462 | Sugiyama | NCL | AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs |
| P20618 | S157 | Sugiyama | PSMB1 PSC5 | IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL |
| P21333 | S1084 | Sugiyama | FLNA FLN FLN1 | PTKPSKVKAFGPGLQGGsAGsPARFtIDTKGAGTGGLGLTV |
| P21333 | S1459 | Sugiyama | FLNA FLN FLN1 | KVPVHDVTDASKVKCsGPGLsPGMVRANLPQsFQVDTSKAG |
| P22234 | S27 | Sugiyama | PAICS ADE2 AIRC PAIS | LNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAGNAARK |
| P22314 | T1016 | Sugiyama | UBA1 A1S9T UBE1 | MLYSFFMPAAKLKERLDQPMtEIVsRVSKRKLGRHVRALVL |
| P22314 | T233 | Sugiyama | UBA1 A1S9T UBE1 | GEQPLSAMVSMVTKDNPGVVtCLDEARHGFESGDFVSFSEV |
| P22626 | S225 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN |
| P22626 | S259 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GFGDGyNGyGGGPGGGNFGGsPGyGGGRGGYGGGGPGYGNQ |
| P23284 | T81 | Sugiyama | PPIB CYPB | IFGLFGKTVPKTVDNFVALAtGEKGFGYKNSKFHRVIKDFM |
| P23396 | T242 | Sugiyama | RPS3 OK/SW-cl.26 | PIsEQKGGKPEPPAMPQPVPtA___________________ |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P23921 | S559 | Sugiyama | RRM1 RR1 | ALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTPTDLW |
| P24752 | S218 | Sugiyama | ACAT1 ACAT MAT | ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV |
| P25705 | S198 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK |
| P25786 | Y6 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | _______________MFRNQyDNDVtVWsPQGRIHQIEYAM |
| P25789 | S13 | Sugiyama | PSMA4 HC9 PSC9 | ________MSRRyDsRttIFsPEGRLYQVEYAMEAIGHAGT |
| P26373 | T148 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV |
| P26373 | T151 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE |
| P26640 | S301 | Sugiyama | VARS1 G7A VARS VARS2 | DLPtPPGEKKDVSGPMPDsysPRYVEAAWYPWWEQQGFFKP |
| P27348 | S45 | Sugiyama | YWHAQ | CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI |
| P27695 | S135 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | SHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDEEHDQEG |
| P28066 | S16 | Sugiyama | PSMA5 | _____MFLTRsEyDRGVNtFsPEGRLFQVEyAIEAIKLGST |
| P28074 | S175 | Sugiyama | PSMB5 LMPX MB1 X | SMGTMICGWDKRGPGLyyVDsEGNRISGATFSVGSGSVYAY |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | T287 | Sugiyama | TKT | AEQIIQEIysQIQsKKKILAtPPQEDAPsVDIANIRMPsLP |
| P29401 | T442 | Sugiyama | TKT | GEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAA |
| P29692 | S162 | Sugiyama | EEF1D EF1D | AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY |
| P29692 | S65 | Sugiyama | EEF1D EF1D | VILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRIA |
| P30041 | T221 | Sugiyama | PRDX6 AOP2 KIAA0106 | LFPKGVFtKELPSGKKYLRYtPQP_________________ |
| P30041 | T44 | Sugiyama | PRDX6 AOP2 KIAA0106 | RFHDFLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKR |
| P30041 | T48 | Sugiyama | PRDX6 AOP2 KIAA0106 | FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL |
| P30041 | T49 | Sugiyama | PRDX6 AOP2 KIAA0106 | LGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKLI |
| P30043 | S198 | Sugiyama | BLVRB FLR SCAN | KHDLGHFMLRCLttDEyDGHstyPsHQyQ____________ |
| P30043 | S82 | Sugiyama | BLVRB FLR SCAN | DKTVAGQDAVIVLLGTRNDLsPTTVMSEGARNIVAAMKAHG |
| P30050 | S157 | Sugiyama | RPL12 | QsVGCNVDGRHPHDIIDDINsGAVECPAs____________ |
| P30050 | S165 | Sugiyama | RPL12 | GRHPHDIIDDINsGAVECPAs____________________ |
| P30050 | S26 | Sugiyama | RPL12 | DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30086 | T42 | Sugiyama | PEBP1 PBP PEBP | QHPLHVTYAGAAVDELGKVLtPtQVKNRPtsIsWDGLDsGK |
| P30101 | S443 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | LsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLN |
| P30101 | T120 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | yPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPASVPLR |
| P30101 | T72 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | FFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTANTNTC |
| P30405 | S207 | Sugiyama | PPIF CYP3 | FGSKsGRTSKKIVItDCGQLs____________________ |
| P30405 | T201 | Sugiyama | PPIF CYP3 | VKKIESFGSKsGRTSKKIVItDCGQLs______________ |
| P31327 | T206 | Sugiyama | CPS1 | EGQPVDFVDPNKQNLIAEVstKDVKVYGKGNPTKVVAVDCG |
| P31327 | T326 | Sugiyama | CPS1 | AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP |
| P31939 | S401 | Sugiyama | ATIC PURH OK/SW-cl.86 | LFGLHLsQKRNNGVVDKSLFsNVVTKNKDLPESALRDLIVA |
| P31939 | T215 | Sugiyama | ATIC PURH OK/SW-cl.86 | KQYSKGVsQMPLRyGMNPHQtPAQLytLQPKLPITVLNGAP |
| P31939 | T221 | Sugiyama | ATIC PURH OK/SW-cl.86 | VsQMPLRyGMNPHQtPAQLytLQPKLPITVLNGAPGFINLC |
| P31939 | Y208 | Sugiyama | ATIC PURH OK/SW-cl.86 | AISDyFRKQYSKGVsQMPLRyGMNPHQtPAQLytLQPKLPI |
| P31943 | S104 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P31946 | S47 | Sugiyama | YWHAB | AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P31947 | S45 | Sugiyama | SFN HME1 | FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI |
| P31948 | Y354 | Sugiyama | STIP1 | DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG |
| P32322 | S294 | Sugiyama | PYCR1 | QEQVSPAAIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLA |
| P32322 | S301 | Sugiyama | PYCR1 | AIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGKD__ |
| P32322 | S303 | Sugiyama | PYCR1 | KKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGKD____ |
| P32322 | T298 | Sugiyama | PYCR1 | SPAAIKKTILDKVKLDsPAGtALsPsGHTKLLPRSLAPAGK |
| P32929 | S56 | Sugiyama | CTH | AVVPPISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVA |
| P33992 | S315 | Sugiyama | MCM5 CDC46 | RVLGIQVDTDGSGRSFAGAVsPQEEEEFRRLAALPNVYEVI |
| P34897 | S90 | Sugiyama | SHMT2 | GLELIAsENFCsRAALEALGsCLNNKYSEGYPGKRyyGGAE |
| P34897 | T420 | Sugiyama | SHMT2 | LELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFREDD |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34931 | T228 | Sugiyama | HSPA1L | DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK |
| P34931 | T39 | Sugiyama | HSPA1L | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P34931 | T47 | Sugiyama | HSPA1L | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P34932 | T364 | Sugiyama | HSPA4 APG2 HSPH2 | ATRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAILs |
| P35579 | T1764 | Sugiyama | MYH9 | NtELINDRLKKANLQIDQINtDLNLERSHAQKNENARQQLE |
| P36578 | S295 | Sugiyama | RPL4 RPL1 | sNyNLPMHKMINtDLsRILKsPEIQRALRAPRKKIHRRVLK |
| P37802 | S145 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN |
| P37802 | T180 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_ |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T398 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA |
| P38646 | T86 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK |
| P38646 | T87 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR |
| P39687 | T105 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | EKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCEV |
| P39687 | T126 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | IEPLKKLENLKsLDLFNCEVtNLNDyRENVFKLLPQLtyLD |
| P40227 | S49 | Sugiyama | CCT6A CCT6 CCTZ | GLQDVLRTNLGPKGTMKMLVsGAGDIKLTKDGNVLLHEMQI |
| P40763 | S727 | GPS6|SIGNOR | STAT3 APRF | KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS |
| P46777 | S172 | Sugiyama | RPL5 MSTP030 | RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA |
| P46777 | S176 | Sugiyama | RPL5 MSTP030 | GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46937 | S128 | SIGNOR|PSP | YAP1 YAP65 | AstDAGtAGALtPQHVRAHssPAsLQLGAVsPGtLtPtGVV |
| P47712 | T426 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | GVSGSQsRGstMEEELENIttKHIVsNDssDsDDEsHEPKG |
| P47756 | S207 | Sugiyama | CAPZB | MNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKIRst |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P48741 | T228 | Sugiyama | HSPA7 HSP70B | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P48741 | T47 | Sugiyama | HSPA7 HSP70B | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P49327 | S207 | Sugiyama | FASN FAS | GINVLLKPNTSVQFLRLGMLsPEGtCKAFDtAGNGYCRSEG |
| P49327 | T1150 | Sugiyama | FASN FAS | ERAALQEELQLCKGLVQALQtKVTQQGLKMVVPGLDGAQIP |
| P49327 | T2215 | Sugiyama | FASN FAS | DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN |
| P49411 | T276 | Sugiyama | TUFM | DLEKPFLLPVEAVYSVPGRGtVVTGTLERGILKKGDECELL |
| P49588 | S188 | Sugiyama | AARS1 AARS | PGNMKDNFWEMGDtGPCGPCsEIHyDRIGGRDAAHLVNQDD |
| P49841 | S389 | Sugiyama | GSK3B | SNPPLATILIPPHARIQAAAstPtNATAASDANTGDRGQTN |
| P50395 | T394 | Sugiyama | GDI2 RABGDIB | EPIEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttC |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50454 | Y135 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | LRSLSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYN |
| P50502 | S181 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | LQKPNAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| P51858 | S165 | Sugiyama | HDGF HMG1L2 | AKEKNEKGALKRRAGDLLEDsPKRPKEAENPEGEEKEAAtL |
| P51991 | S358 | Sugiyama | HNRNPA3 HNRPA3 | QQQSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF |
| P51991 | Y360 | Sugiyama | HNRNPA3 HNRPA3 | QSNYGPMKGGsFGGRssGsPyGGGyGsGGGsGGyGsRRF__ |
| P52597 | S100 | Sugiyama | HNRNPF HNRPF | HRyIEVFKSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPF |
| P53396 | S481 | Sugiyama | ACLY | ADEVAPAKKAKPAMPQDsVPsPRSLQGKSTTLFSRHTKAIV |
| P53621 | S1188 | Sugiyama | COPA | ICAASYRPIYRGKPVEKCPLsGACYsPEFKGQICRVTTVTE |
| P53621 | S173 | Sugiyama | COPA | ASLDQTVRVWDISGLRKKNLsPGAVEsDVRGITGVDLFGTT |
| P53621 | S268 | Sugiyama | COPA | HyNNVSCAVFHPRQELILsNsEDKSIRVWDMSKRTGVQTFR |
| P53992 | S328 | Sugiyama | SEC24C KIAA0079 | sQPGPPQPLPPKRLDPDAIPsPIQVIEDDRNNRGTEPFVTG |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P54652 | T38 | Sugiyama | HSPA2 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P54652 | T46 | Sugiyama | HSPA2 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P55795 | S104 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P55809 | S509 | Sugiyama | OXCT1 OXCT SCOT | LWEGLTVDDVQKSTGCDFAVsPKLMPMQQIAN_________ |
| P60174 | T38 | Sugiyama | TPI1 TPI | RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP |
| P60174 | T46 | Sugiyama | TPI1 TPI | IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN |
| P60174 | Y48 | Sugiyama | TPI1 TPI | tLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQNCy |
| P60660 | T44 | Sugiyama | MYL6 | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDEMNVKV |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S300 | Sugiyama | ACTB | NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | T106 | Sugiyama | ACTB | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P60709 | T202 | Sugiyama | ACTB | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P60709 | T303 | Sugiyama | ACTB | MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs |
| P60709 | T318 | Sugiyama | ACTB | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60709 | Y294 | Sugiyama | ACTB | IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ |
| P61158 | S418 | Sugiyama | ACTR3 ARP3 | KDyEEIGPsICRHNPVFGVMs____________________ |
| P61254 | T8 | Sugiyama | RPL26 | _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK |
| P61916 | S40 | Sugiyama | NPC2 HE1 | EPVQFKDCGsVDGVIKEVNVsPCPtQPCQLSKGQSYSVNVT |
| P61978 | S284 | Sugiyama | HNRNPK HNRPK | MPPGRGGRPMPPSRRDyDDMsPRRGPPPPPPGRGGRGGsRA |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61978 | Y72 | Sugiyama | HNRNPK HNRPK | KNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISA |
| P61981 | S38 | Sugiyama | YWHAG | ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS |
| P61981 | S46 | Sugiyama | YWHAG | AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P61981 | T31 | Sugiyama | YWHAG | ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN |
| P62195 | T109 | Sugiyama | PSMC5 SUG1 | VHPEGKFVVDVDKNIDINDVtPNCRVALRNDsytLHKILPN |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S46 | Sugiyama | YWHAE | SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI |
| P62263 | S137 | Sugiyama | RPS14 PRO2640 | RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______ |
| P62263 | T133 | Sugiyama | RPS14 PRO2640 | QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__ |
| P62714 | S212 | Sugiyama | PPP2CB | EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62736 | T320 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62857 | T57 | Sugiyama | RPS28 | DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________ |
| P62913 | T44 | Sugiyama | RPL11 | ICVGEsGDRLtRAAKVLEQLtGQtPVFsKARyTVRsFGIRR |
| P62913 | T47 | Sugiyama | RPL11 | GEsGDRLtRAAKVLEQLtGQtPVFsKARyTVRsFGIRRNEK |
| P62942 | S9 | Sugiyama | FKBP1A FKBP1 FKBP12 | ____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | S45 | Sugiyama | YWHAZ | CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI |
| P63173 | T14 | Sugiyama | RPL38 | _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S300 | Sugiyama | ACTG1 ACTG | NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | T106 | Sugiyama | ACTG1 ACTG | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P63261 | T202 | Sugiyama | ACTG1 ACTG | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63261 | T303 | Sugiyama | ACTG1 ACTG | MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs |
| P63261 | T318 | Sugiyama | ACTG1 ACTG | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63261 | Y294 | Sugiyama | ACTG1 ACTG | IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P63267 | T319 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P67775 | S212 | Sugiyama | PPP2CA | EGPMCDLLWSDPDDRGGWGIsPRGAGYTFGQDISETFNHAN |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68032 | T320 | Sugiyama | ACTC1 ACTC | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68104 | T261 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68133 | T320 | Sugiyama | ACTA1 ACTA | VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68363 | T334 | Sugiyama | TUBA1B | ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG |
| P68363 | T51 | Sugiyama | TUBA1B | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P68363 | Y432 | Sugiyama | TUBA1B | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| P84022 | S208 | GPS6|PSP | SMAD3 MADH3 | DGETSDHQMNHSMDAGsPNLsPNPMsPAHNNLDLQPVTYCE |
| P85037 | S420 | Sugiyama | FOXK1 MNF | RGVSCFRtPFGPLssRsAPAsPtHPGLMsPRsGGLQtPECL |
| P85037 | S428 | Sugiyama | FOXK1 MNF | PFGPLssRsAPAsPtHPGLMsPRsGGLQtPECLsREGsPIP |
| Q00610 | S886 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG |
| Q01105 | S165 | Sugiyama | SET | PyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQ |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q02078 | T312 | GPS6 | MEF2A MEF2 | EELELNTQRISSSQATQPLAtPVVSVTtPSLPPQGLVYSAM |
| Q02543 | T24 | Sugiyama | RPL18A | SGTLREYKVVGRCLPTPKCHtPPLYRMRIFAPNHVVAKSRF |
| Q04637 | S1231 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | tEDRDRGRDAVKREAALPPVsPLKAALsEEELEKKsKAIIE |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q04917 | T31 | Sugiyama | YWHAH YWHA1 | ARLAEQAERyDDMAsAMKAVtELNEPLsNEDRNLLsVAyKN |
| Q05639 | T261 | Sugiyama | EEF1A2 EEF1AL STN | PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA |
| Q06323 | S55 | Sugiyama | PSME1 IFI5111 | KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE |
| Q06830 | T166 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | DLPVGRsVDEtLRLVQAFQFtDKHGEVCPAGWKPGsDtIKP |
| Q07020 | S140 | Sugiyama | RPL18 | ILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAPGtPH |
| Q07020 | T136 | Sugiyama | RPL18 | AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP |
| Q08J23 | T718 | Sugiyama | NSUN2 SAKI TRM4 | YLRMMGLEVLGEKKKEGVILtNEsAAstGQPDNDVtEGQRA |
| Q09028 | S147 | Sugiyama | RBBP4 RBAP48 | VNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGEC |
| Q09666 | S41 | Sugiyama | AHNAK PM227 | HGLTIAQRDDGVFVQEVtQNsPAARTGVVKEGDQIVGATIy |
| Q12778 | S329 | SIGNOR|PSP | FOXO1 FKHR FOXO1A | NWSTFRPRtssNAstIsGRLsPIMtEQDDLGEGDVHSMVYP |
| Q13200 | S16 | Sugiyama | PSMD2 TRAP2 | _____MEEGGRDKAPVQPQQsPAAAPGGtDEKPsGKERRDA |
| Q13283 | S232 | Sugiyama | G3BP1 G3BP | EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA |
| Q13404 | S146 | Sugiyama | UBE2V1 CROC1 UBE2V UEV1 P/OKcl.19 | RLMMSKENMKLPQPPEGQCysN___________________ |
| Q13485 | S138 | GPS6|PSP | SMAD4 DPC4 MADH4 | AFDLKCDSVCVNPYHYERVVsPGIDLSGLTLQSNAPSsMMV |
| Q13485 | T9 | GPS6|PSP | SMAD4 DPC4 MADH4 | ____________MDNMSITNtPTSNDACLSIVHSLMCHRQG |
| Q13509 | S172 | Sugiyama | TUBB3 TUBB4 | ISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLSIHQL |
| Q13509 | T166 | Sugiyama | TUBB3 TUBB4 | GMGTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNAT |
| Q14103 | S190 | Sugiyama | HNRNPD AUF1 HNRPD | KRAKAMKTKEPVKKIFVGGLsPDtPEEKIREYFGGFGEVES |
| Q14157 | S471 | Sugiyama | UBAP2L KIAA0144 NICE4 | PPssPLPsKstsAPQMsPGssDNQsssPQPAQQKLKQQKKK |
| Q14204 | S2410 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | GEDEAQRRRKGKEDEGEEAAsPMLQIQRDAATIMQPYFTSN |
| Q14258 | S100 | Sugiyama | TRIM25 EFP RNF147 ZNF147 | DLAREPPADVWtPPARAsAPsPNAQVACDHCLKEAAVKTCL |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14677 | S164 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | RLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKW |
| Q14694 | S370 | Sugiyama | USP10 KIAA0190 | KPssssPVAYVEtKysPPAIsPLVSEKQVEVKEGLVPVSED |
| Q14C86 | S1019 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | QEKDKDDLGPDRFstLTDDPsPRLSAQAQVAEDILDKYRNA |
| Q15080 | S67 | Sugiyama | NCF4 SH3PXD4 | TKGGSKYLIYRRYRQFHALQsKLEERFGPDSKSSALACTLP |
| Q15181 | S127 | Sugiyama | PPA1 IOPPP PP | NDKHTGCCGDNDPIDVCEIGsKVCARGEIIGVKVLGILAMI |
| Q15181 | S250 | Sugiyama | PPA1 IOPPP PP | LVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDALPPPC |
| Q15181 | T245 | Sugiyama | PPA1 IOPPP PP | DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA |
| Q15293 | T76 | Sugiyama | RCN1 RCN | FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD |
| Q15365 | S190 | Sugiyama | PCBP1 | LsQsPQGRVMtIPyQPMPAssPVICAGGQDRCsDAAGYPHA |
| Q15642 | T302 | Sugiyama | TRIP10 CIP4 STOT STP | VEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRSRTKRWP |
| Q15796 | S250 | GPS6|PSP | SMAD2 MADH2 MADR2 | GETSDQQLNQsMDtGsPAELsPTTLsPVNHsLDLQPVTYSE |
| Q16204 | S244 | Sugiyama | CCDC6 D10S170 TST1 | LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF |
| Q16576 | S146 | Sugiyama | RBBP7 RBAP46 | VNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGEC |
| Q53EL6 | S94 | Sugiyama | PDCD4 H731 | GDsVsDsGsDALRSGLtVPtsPKGRLLDRRSRSGKGRGLPK |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q5T4S7 | S178 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | AKLPQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLT |
| Q5T4S7 | S181 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | PQTVKTLSDVEDQKELAsPVsPELRQKEVQMNFLNQLTSVF |
| Q5VTE0 | T261 | Sugiyama | EEF1A1P5 EEF1AL3 | PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA |
| Q6PCE3 | S175 | Sugiyama | PGM2L1 BM32A | PFVPYAVQKLKAVAGVMItAsHNRKEDNGYKVYWETGAQIT |
| Q6PCE3 | T173 | Sugiyama | PGM2L1 BM32A | PTPFVPYAVQKLKAVAGVMItAsHNRKEDNGYKVYWETGAQ |
| Q6PEY2 | T334 | Sugiyama | TUBA3E | ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q6PEY2 | T51 | Sugiyama | TUBA3E | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q6PKG0 | T769 | Sugiyama | LARP1 KIAA0731 LARP | ALANKLFGAPEPstIARsLPttVPEsPNyRNtRtPRtPRtP |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71U36 | T334 | Sugiyama | TUBA1A TUBA3 | ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q71U36 | T51 | Sugiyama | TUBA1A TUBA3 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q71U36 | Y432 | Sugiyama | TUBA1A TUBA3 | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| Q7Z417 | S692 | Sugiyama | NUFIP2 KIAA1321 PIG1 | IWNLQKQDPKRIItyNEAMDsPDQ_________________ |
| Q86UY5 | S353 | Sugiyama | FAM83A TSGP | NPFSGRSAGSHPGTRsVsAssGPCsPAAPHPPPPPRFQPHQ |
| Q86VP6 | S376 | Sugiyama | CAND1 KIAA0829 TIP120 TIP120A | CLDAVVSTRHEMLPEFyKTVsPALISRFKEREENVKADVFH |
| Q8IXK0 | S751 | Sugiyama | PHC2 EDR2 PH2 | tHsQEDssRCSDNSSYEEPLsPIsASSSTSRRRQGQRDLEL |
| Q8N122 | S863 | SIGNOR|PSP | RPTOR KIAA1303 RAPTOR | VNARPQRVLDtssLtQsAPAsPtNKGVHIHQAGGsPPAsst |
| Q8NBJ5 | S612 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | QKMREQQALSREAKNsDVLQsPLDsAARDEL__________ |
| Q8NBJ5 | S616 | Sugiyama | COLGALT1 GLT25D1 PSEC0241 | EQQALSREAKNsDVLQsPLDsAARDEL______________ |
| Q8NBJ7 | S44 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | NGQATSMVQLQGGRFLMGtNsPDSRDGDGPVREATVKPFAI |
| Q8NBS9 | S255 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | EHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDGKKVD |
| Q8NEN9 | S503 | Sugiyama | PDZD8 PDZK8 | AGLTVDTESRELDsEFEDLAsDVRAQNEFKDEAQsLsHsPK |
| Q8NEZ2 | S18 | Sugiyama | VPS37A HCRP1 | ___MSWLFPLTKsAsssAAGsPGGLTSLQQQKQRLIESLRN |
| Q8NFD5 | S1744 | Sugiyama | ARID1B BAF250B DAN15 KIAA1235 OSA2 | ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI |
| Q8NFI4 | S181 | Sugiyama | ST13P5 FAM10A5 | LQKPNAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| Q8WU90 | S351 | Sugiyama | ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 | DIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLsEAs |
| Q8WWM7 | S111 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | PGAAAIGsARGQstGKGPPQsPVFEGVyNNSRMLHFLTAVV |
| Q8WXI9 | S135 | Sugiyama | GATAD2B KIAA1150 | ERGRLtPsPDIIVLsDNEAssPRsSsRMEERLKAANLEMFK |
| Q8WXI9 | T120 | Sugiyama | GATAD2B KIAA1150 | INDEPVDMSARRsEPERGRLtPsPDIIVLsDNEAssPRsSs |
| Q92530 | S152 | Sugiyama | PSMF1 | SRIVSGIITPIHEQWEKANVssPHREFPPAtAREVDPLRIP |
| Q92530 | T162 | Sugiyama | PSMF1 | IHEQWEKANVssPHREFPPAtAREVDPLRIPPHHPHTSRQP |
| Q92688 | T126 | Sugiyama | ANP32B APRIL PHAPI2 | LEPLKKLECLKsLDLFNCEVtNLNDyREsVFKLLPQLTYLD |
| Q96C19 | S74 | Sugiyama | EFHD2 SWS1 | ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI |
| Q96EK9 | S184 | Sugiyama | KTI12 SBBI81 | GSAQADVPKELEREEsGAAEsPALVtPDSEKSAKHGsGAFy |
| Q96EN8 | S530 | Sugiyama | MOCOS | APSADSQADVIPAVMGRRsLsPQEDALTGSRVWNNSSTVNA |
| Q96S59 | T163 | Sugiyama | RANBP9 RANBPM | QEKELQRRLKRLYPAVDEQEtPLPRSWsPKDKFsYIGLsQN |
| Q99613 | S754 | Sugiyama | EIF3C EIF3S8 | REHVVAASKAMKMGDWKTCHsFIINEKMNGKVWDLFPEADK |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q9BQE3 | T334 | Sugiyama | TUBA1C TUBA6 | ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q9BQE3 | T51 | Sugiyama | TUBA1C TUBA6 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q9BQG0 | S11 | Sugiyama | MYBBP1A P160 | __________MEsRDPAQPMsPGEAtQsGARPADRYGLLKH |
| Q9BX68 | T47 | Sugiyama | HINT2 | QVRGAAGVTDGNEVAKAQQAtPGGAAPtIFsRILDKsLPAD |
| Q9BX68 | T54 | Sugiyama | HINT2 | VTDGNEVAKAQQAtPGGAAPtIFsRILDKsLPADILyEDQQ |
| Q9BXP5 | S493 | Sugiyama | SRRT ARS2 ASR2 | VNIKEICWNLQNIRLRECELsPGVNRDLTRRVRNINGITQH |
| Q9BXS5 | T422 | Sugiyama | AP1M1 CLTNM | GYQALPWVRYITQNGDyQLRtQ___________________ |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9C0C2 | S1103 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ |
| Q9H0L4 | S563 | Sugiyama | CSTF2T KIAA0689 | IQGGGIQGASKQGGsQPssFsPGQsQVtPQDQEKAALIMQV |
| Q9H1A4 | S355 | Sugiyama | ANAPC1 TSG24 | PsLHsRsPsISNMAALsRAHsPALGVHsFsGVQRFNIssHN |
| Q9H1A4 | S362 | Sugiyama | ANAPC1 TSG24 | PsISNMAALsRAHsPALGVHsFsGVQRFNIssHNQsPKRHS |
| Q9H2U2 | S317 | Sugiyama | PPA2 HSPC124 | DSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK___ |
| Q9H4A3 | S1261 | Sugiyama | WNK1 HSN2 KDP KIAA0344 PRKWNK1 | GIPTSSLTQVVHSAGRRFIVsPVPEsRLRESKVFPSEITDT |
| Q9HAP6 | S115 | Sugiyama | LIN7B MALS2 VELI2 UNQ3116/PRO10200 | ELPKTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLK |
| Q9NQB0 | T201 | GPS6|SIGNOR|PSP | TCF7L2 TCF4 | AHIVsNKVPVVQHPHHVHPLtPLITYSNEHFtPGNPPPHLP |
| Q9NQB0 | T212 | GPS6|SIGNOR|PSP | TCF7L2 TCF4 | QHPHHVHPLtPLITYSNEHFtPGNPPPHLPADVDPKTGIPR |
| Q9NSE4 | T83 | Sugiyama | IARS2 | TVLLPQTSFPMKLLGRQQPDtELEIQQKCGFSELysWQRER |
| Q9NUP9 | S115 | Sugiyama | LIN7C MALS3 VELI3 | ELPKTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLK |
| Q9NYB0 | S203 | Sugiyama | TERF2IP DRIP5 RAP1 PP8000 | RYLKHLRGQEHKyLLGDAPVsPssQKLKRKAEEDPEAADsG |
| Q9NZT2 | S378 | Sugiyama | OGFR | LERsQGDEAGGHGEDRPEPLsPKEsKKRKLELSRREQPPTE |
| Q9P1U1 | S418 | Sugiyama | ACTR3B ARP11 ARP4 | KDYEEYGPSICRHNPVFGVMs____________________ |
| Q9UBE8 | S232 | Sugiyama | NLK LAK1 | FEEIYVVTELMQSDLHKIIVsPQPLsSDHVKVFLYQILRGL |
| Q9UBE8 | S237 | Sugiyama | NLK LAK1 | VVTELMQSDLHKIIVsPQPLsSDHVKVFLYQILRGLKYLHS |
| Q9UBE8 | S294 | Sugiyama | NLK LAK1 | SNCVLKICDFGLARVEELDEsRHMtQEVVtQYYRAPEILMG |
| Q9UBE8 | T298 | GPS6|EPSD|Sugiyama | NLK LAK1 | LKICDFGLARVEELDEsRHMtQEVVtQYYRAPEILMGSRHY |
| Q9UBE8 | T303 | Sugiyama | NLK LAK1 | FGLARVEELDEsRHMtQEVVtQYYRAPEILMGSRHYSNAID |
| Q9UGV2 | S341 | Sugiyama | NDRG3 | MTRLARsRtHstsssLGsGEsPFsRsVtsNQsDGtQESCEs |
| Q9UGV2 | S361 | Sugiyama | NDRG3 | sPFsRsVtsNQsDGtQESCEsPDVLDRHQTMEVsC______ |
| Q9UJU2 | S132 | PSP | LEF1 | SGyIMMPNMNNDPYMSNGSLsPPIPRTSNKVPVVQPSHAVH |
| Q9UJU2 | S166 | GPS6|SIGNOR|ELM|iPTMNet|PSP | LEF1 | QPSHAVHPLtPLITYSDEHFsPGSHPSHIPSDVNSKQGMSR |
| Q9UJU2 | S200 | PSP | LEF1 | SKQGMSRHPPAPDIPTFYPLsPGGVGQItPPLGWQGQPVYP |
| Q9UJU2 | T155 | GPS6|SIGNOR|ELM|iPTMNet|PSP | LEF1 | IPRTSNKVPVVQPSHAVHPLtPLITYSDEHFsPGSHPSHIP |
| Q9UJU2 | T265 | PSP | LEF1 | HMIPGPPGPHTTGIPHPAIVtPQVKQEHPHTDSDLMHVKPQ |
| Q9ULD2 | S1264 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | RsPtssAIPLQsPRNsGsFPsPsIsPR______________ |
| Q9ULD2 | S1268 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | ssAIPLQsPRNsGsFPsPsIsPR__________________ |
| Q9UNE7 | S23 | Sugiyama | STUB1 CHIP PP1131 | GKEEKEGGARLGAGGGsPEKsPsAQELKEQGNRLFVGRKYP |
| Q9UNX3 | T8 | Sugiyama | RPL26L1 RPL26P1 | _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK |
| Q9UNZ2 | S271 | Sugiyama | NSFL1C UBXN2C | KAFTGEGQKLGstAPQVLstssPAQQAENEAKAsSSILIDE |
| Q9Y2V2 | S41 | Sugiyama | CARHSP1 | LDtPRsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGP |
| Q9Y2V2 | T45 | Sugiyama | CARHSP1 | RsRERsPsPLRGNVVPsPLPtRRtRtFsAtVRASQGPVYKG |
| Q9Y3F4 | T225 | Sugiyama | STRAP MAWD UNRIP | SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF |
| Q9Y5M8 | S257 | Sugiyama | SRPRB PSEC0230 | LPLKVEFLECSAKGGRGDVGsADIQDLEKWLAKIA______ |
| Q9Y5X3 | S60 | Sugiyama | SNX5 | SERDKVKFTVHTKTTLPtFQsPEFSVTRQHEDFVWLHDTLI |
| Q9Y5X3 | T57 | Sugiyama | SNX5 | DALSERDKVKFTVHTKTTLPtFQsPEFSVTRQHEDFVWLHD |
| Q9Y6Q9 | S505 | PSP | NCOA3 AIB1 BHLHE42 RAC3 TRAM1 | RNRGSPKIASHQFSPVAGVHsPMAsSGNTGNHSFSSSSLSA |
| Q9Y6Q9 | S543 | PSP | NCOA3 AIB1 BHLHE42 RAC3 TRAM1 | LSALQAISEGVGTSLLSTLSsPGPKLDNsPNMNITQPSKVs |
| Q9Y6Q9 | S857 | PSP | NCOA3 AIB1 BHLHE42 RAC3 TRAM1 | LGLKSSQSVQSIRPPYNRAVsLDsPVsVGssPPVKNISAFP |
| Q9Y6Q9 | S860 | PSP | NCOA3 AIB1 BHLHE42 RAC3 TRAM1 | KSSQSVQSIRPPYNRAVsLDsPVsVGssPPVKNISAFPMLP |
| Q9Y6Q9 | S867 | PSP | NCOA3 AIB1 BHLHE42 RAC3 TRAM1 | SIRPPYNRAVsLDsPVsVGssPPVKNISAFPMLPKQPMLGG |
| Q9Y6Q9 | T24 | PSP | NCOA3 AIB1 BHLHE42 RAC3 TRAM1 | LGENLDPLAsDSRKRKLPCDtPGQGLtCsGEKRRREQESKY |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle, Mitotic | R-HSA-69278 | 1.160394e-11 | 10.935 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 4.097744e-11 | 10.387 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.399402e-07 | 6.854 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.935381e-07 | 6.532 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 7.331450e-06 | 5.135 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 1.678000e-05 | 4.775 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 1.871653e-05 | 4.728 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 2.040396e-05 | 4.690 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.598464e-05 | 4.585 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.997499e-05 | 4.523 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.916744e-05 | 4.407 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 4.066595e-05 | 4.391 | 0 | 0 |
| M Phase | R-HSA-68886 | 4.127647e-05 | 4.384 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 4.626245e-05 | 4.335 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 7.154751e-05 | 4.145 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 7.023790e-05 | 4.153 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 7.247856e-05 | 4.140 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 7.264035e-05 | 4.139 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 6.683265e-05 | 4.175 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 7.116642e-05 | 4.148 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 6.550595e-05 | 4.184 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 9.582392e-05 | 4.019 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 9.582392e-05 | 4.019 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 9.671719e-05 | 4.014 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 9.671719e-05 | 4.014 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 9.575708e-05 | 4.019 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 9.698526e-05 | 4.013 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.003809e-04 | 3.998 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.175903e-04 | 3.930 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.250521e-04 | 3.903 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.285755e-04 | 3.891 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 1.619845e-04 | 3.791 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 1.619845e-04 | 3.791 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.723574e-04 | 3.764 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.723574e-04 | 3.764 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 1.859623e-04 | 3.731 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 1.920569e-04 | 3.717 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.275057e-04 | 3.643 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 2.830813e-04 | 3.548 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 3.117257e-04 | 3.506 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 3.740103e-04 | 3.427 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 4.116850e-04 | 3.385 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 4.993050e-04 | 3.302 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 4.592783e-04 | 3.338 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.531128e-04 | 3.344 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 4.759850e-04 | 3.322 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 4.908748e-04 | 3.309 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 4.955431e-04 | 3.305 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 5.647196e-04 | 3.248 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 6.037617e-04 | 3.219 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 6.783532e-04 | 3.169 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 6.783532e-04 | 3.169 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 8.047296e-04 | 3.094 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 8.406644e-04 | 3.075 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 9.928402e-04 | 3.003 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 9.928402e-04 | 3.003 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.178828e-03 | 2.929 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.232950e-03 | 2.909 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.495534e-03 | 2.825 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.534095e-03 | 2.814 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.522472e-03 | 2.817 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.686320e-03 | 2.773 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.706960e-03 | 2.768 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.775318e-03 | 2.751 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.838261e-03 | 2.736 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.843029e-03 | 2.734 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 1.880180e-03 | 2.726 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.098003e-03 | 2.678 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.225044e-03 | 2.653 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 2.348830e-03 | 2.629 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 2.481350e-03 | 2.605 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 2.555581e-03 | 2.593 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.654078e-03 | 2.576 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.936949e-03 | 2.532 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 3.079398e-03 | 2.512 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 3.189543e-03 | 2.496 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 3.256750e-03 | 2.487 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 3.286192e-03 | 2.483 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 3.570818e-03 | 2.447 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 3.951771e-03 | 2.403 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 4.007149e-03 | 2.397 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.007149e-03 | 2.397 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 4.109280e-03 | 2.386 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 4.270724e-03 | 2.369 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 4.698593e-03 | 2.328 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 4.930719e-03 | 2.307 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 4.941240e-03 | 2.306 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 5.379869e-03 | 2.269 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 5.531307e-03 | 2.257 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 5.554730e-03 | 2.255 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 5.554730e-03 | 2.255 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 5.709054e-03 | 2.243 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 5.748871e-03 | 2.240 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 5.903809e-03 | 2.229 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 6.219900e-03 | 2.206 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 6.280708e-03 | 2.202 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 6.378947e-03 | 2.195 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 6.378947e-03 | 2.195 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 7.235252e-03 | 2.141 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.975852e-03 | 2.098 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 7.975852e-03 | 2.098 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 7.847584e-03 | 2.105 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 8.305240e-03 | 2.081 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 8.518516e-03 | 2.070 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 9.240416e-03 | 2.034 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 9.571368e-03 | 2.019 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 1.036480e-02 | 1.984 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 9.879473e-03 | 2.005 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.046731e-02 | 1.980 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 9.879473e-03 | 2.005 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.067001e-02 | 1.972 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 1.084505e-02 | 1.965 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 1.084505e-02 | 1.965 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.104180e-02 | 1.957 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.163956e-02 | 1.934 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 1.221053e-02 | 1.913 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.323501e-02 | 1.878 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.323501e-02 | 1.878 | 0 | 0 |
| S Phase | R-HSA-69242 | 1.241594e-02 | 1.906 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.399206e-02 | 1.854 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 1.399206e-02 | 1.854 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.439765e-02 | 1.842 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.752059e-02 | 1.756 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.720444e-02 | 1.764 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.719608e-02 | 1.765 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 1.711079e-02 | 1.767 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 1.658690e-02 | 1.780 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 1.658690e-02 | 1.780 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 1.853419e-02 | 1.732 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 2.204859e-02 | 1.657 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.409406e-02 | 1.618 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 3.234015e-02 | 1.490 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 3.234015e-02 | 1.490 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 3.234015e-02 | 1.490 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 3.234015e-02 | 1.490 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 3.234015e-02 | 1.490 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 3.234015e-02 | 1.490 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 3.234015e-02 | 1.490 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 3.234015e-02 | 1.490 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 2.685258e-02 | 1.571 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 2.733887e-02 | 1.563 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 2.595529e-02 | 1.586 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 2.725932e-02 | 1.564 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 3.033629e-02 | 1.518 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 3.235629e-02 | 1.490 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 3.173633e-02 | 1.498 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 2.751941e-02 | 1.560 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 2.632833e-02 | 1.580 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 3.040849e-02 | 1.517 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 2.457673e-02 | 1.609 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.990152e-02 | 1.524 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 2.463052e-02 | 1.609 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 2.463052e-02 | 1.609 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 3.013691e-02 | 1.521 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 2.945804e-02 | 1.531 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.376221e-02 | 1.472 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 3.376221e-02 | 1.472 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 3.381822e-02 | 1.471 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 3.424933e-02 | 1.465 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 3.541990e-02 | 1.451 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.560645e-02 | 1.448 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 3.689906e-02 | 1.433 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 3.731499e-02 | 1.428 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 3.689906e-02 | 1.433 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 3.866633e-02 | 1.413 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 3.694801e-02 | 1.432 | 0 | 0 |
| Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells | R-HSA-210746 | 3.866633e-02 | 1.413 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 4.052134e-02 | 1.392 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 4.218817e-02 | 1.375 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 4.218817e-02 | 1.375 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 4.537129e-02 | 1.343 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 4.817902e-02 | 1.317 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 4.917425e-02 | 1.308 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 5.036940e-02 | 1.298 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 5.044443e-02 | 1.297 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 5.047551e-02 | 1.297 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 5.047551e-02 | 1.297 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 5.047551e-02 | 1.297 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 5.260673e-02 | 1.279 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.277901e-02 | 1.278 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 5.277901e-02 | 1.278 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 5.277901e-02 | 1.278 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 5.277901e-02 | 1.278 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 5.301185e-02 | 1.276 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 5.301185e-02 | 1.276 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 5.301185e-02 | 1.276 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 5.301185e-02 | 1.276 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 5.323972e-02 | 1.274 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 5.392770e-02 | 1.268 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 5.809768e-02 | 1.236 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 6.092760e-02 | 1.215 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 5.533651e-02 | 1.257 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 5.551404e-02 | 1.256 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 5.392101e-02 | 1.268 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 5.357363e-02 | 1.271 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 6.117128e-02 | 1.213 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 6.117128e-02 | 1.213 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 6.206068e-02 | 1.207 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 6.397587e-02 | 1.194 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 6.397587e-02 | 1.194 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 6.401742e-02 | 1.194 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 6.401742e-02 | 1.194 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 6.401742e-02 | 1.194 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 6.401742e-02 | 1.194 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 6.401742e-02 | 1.194 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.551240e-02 | 1.184 | 0 | 0 |
| Transport of glycerol from adipocytes to the liver by Aquaporins | R-HSA-432030 | 6.649489e-02 | 1.177 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 7.588325e-02 | 1.120 | 0 | 0 |
| IRS activation | R-HSA-74713 | 7.588325e-02 | 1.120 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 7.588325e-02 | 1.120 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 7.588325e-02 | 1.120 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 6.986068e-02 | 1.156 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 6.986068e-02 | 1.156 | 0 | 0 |
| RSK activation | R-HSA-444257 | 6.986068e-02 | 1.156 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 6.986068e-02 | 1.156 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 6.986068e-02 | 1.156 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 7.667681e-02 | 1.115 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 7.667681e-02 | 1.115 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 7.667681e-02 | 1.115 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 6.911685e-02 | 1.160 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 6.645336e-02 | 1.177 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 7.245136e-02 | 1.140 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 7.284630e-02 | 1.138 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 6.911685e-02 | 1.160 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 6.951996e-02 | 1.158 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 6.951996e-02 | 1.158 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 6.790562e-02 | 1.168 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 6.649489e-02 | 1.177 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 7.306387e-02 | 1.136 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 7.328646e-02 | 1.135 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 7.517706e-02 | 1.124 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 7.779567e-02 | 1.109 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 8.056927e-02 | 1.094 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 8.153243e-02 | 1.089 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 8.259404e-02 | 1.083 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 8.554439e-02 | 1.068 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 8.614462e-02 | 1.065 | 1 | 0 |
| HIV Infection | R-HSA-162906 | 8.641826e-02 | 1.063 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 8.740664e-02 | 1.058 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 8.911712e-02 | 1.050 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 8.911712e-02 | 1.050 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 8.911712e-02 | 1.050 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 8.911712e-02 | 1.050 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 8.911712e-02 | 1.050 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 8.911712e-02 | 1.050 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 9.318837e-02 | 1.031 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 9.473356e-02 | 1.023 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 9.612742e-02 | 1.017 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.001323e-01 | 0.999 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 1.001513e-01 | 0.999 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 1.006946e-01 | 0.997 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 1.006946e-01 | 0.997 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 1.081485e-01 | 0.966 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 1.026434e-01 | 0.989 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.026434e-01 | 0.989 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 1.026434e-01 | 0.989 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 1.026434e-01 | 0.989 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.026434e-01 | 0.989 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.106304e-01 | 0.956 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 1.099788e-01 | 0.959 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 1.099788e-01 | 0.959 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 1.208662e-01 | 0.918 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.177108e-01 | 0.929 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 1.208662e-01 | 0.918 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 1.106304e-01 | 0.956 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.099788e-01 | 0.959 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 1.150184e-01 | 0.939 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.026434e-01 | 0.989 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 1.060088e-01 | 0.975 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 1.060088e-01 | 0.975 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 1.150184e-01 | 0.939 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 1.106304e-01 | 0.956 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.213642e-01 | 0.916 | 0 | 0 |
| Defective Base Excision Repair Associated with NEIL1 | R-HSA-9616334 | 1.301368e-01 | 0.886 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.301368e-01 | 0.886 | 0 | 0 |
| Deletions in the AXIN1 gene destabilize the destruction complex | R-HSA-5467345 | 1.301368e-01 | 0.886 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.301368e-01 | 0.886 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.303449e-01 | 0.885 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 1.325469e-01 | 0.878 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 1.325469e-01 | 0.878 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 1.348440e-01 | 0.870 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 1.351240e-01 | 0.869 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.351240e-01 | 0.869 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.364404e-01 | 0.865 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 1.398522e-01 | 0.854 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.433446e-01 | 0.614 | 0 | 0 |
| MGMT-mediated DNA damage reversal | R-HSA-5657655 | 2.433446e-01 | 0.614 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 2.433446e-01 | 0.614 | 0 | 0 |
| Impaired BRCA2 binding to SEM1 (DSS1) | R-HSA-9763198 | 2.433446e-01 | 0.614 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 2.433446e-01 | 0.614 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 2.433446e-01 | 0.614 | 0 | 0 |
| Impaired BRCA2 translocation to the nucleus | R-HSA-9709275 | 2.433446e-01 | 0.614 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.433446e-01 | 0.614 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 2.433446e-01 | 0.614 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 1.547726e-01 | 0.810 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.547726e-01 | 0.810 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 1.547726e-01 | 0.810 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 1.547726e-01 | 0.810 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 1.547726e-01 | 0.810 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 2.043692e-01 | 0.690 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 2.043692e-01 | 0.690 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 2.043692e-01 | 0.690 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 2.043692e-01 | 0.690 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 3.418247e-01 | 0.466 | 0 | 0 |
| Nef mediated downregulation of CD28 cell surface expression | R-HSA-164939 | 3.418247e-01 | 0.466 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 3.418247e-01 | 0.466 | 0 | 0 |
| t(4;14) translocations of FGFR3 | R-HSA-2033515 | 3.418247e-01 | 0.466 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 3.418247e-01 | 0.466 | 0 | 0 |
| Signaling by FGFR3 fusions in cancer | R-HSA-8853334 | 3.418247e-01 | 0.466 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.418247e-01 | 0.466 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.418247e-01 | 0.466 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 3.418247e-01 | 0.466 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.418247e-01 | 0.466 | 0 | 0 |
| Defective MMADHC causes MMAHCD | R-HSA-3359473 | 3.418247e-01 | 0.466 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 3.418247e-01 | 0.466 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 3.418247e-01 | 0.466 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 3.418247e-01 | 0.466 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 3.418247e-01 | 0.466 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 3.418247e-01 | 0.466 | 0 | 0 |
| Intestinal infectious diseases | R-HSA-8942233 | 3.418247e-01 | 0.466 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 3.418247e-01 | 0.466 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 3.418247e-01 | 0.466 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 3.418247e-01 | 0.466 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 1.650450e-01 | 0.782 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.650450e-01 | 0.782 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.650450e-01 | 0.782 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 2.553760e-01 | 0.593 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 2.553760e-01 | 0.593 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.995842e-01 | 0.700 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.995842e-01 | 0.700 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 1.995842e-01 | 0.700 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 1.995842e-01 | 0.700 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 1.995842e-01 | 0.700 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.503897e-01 | 0.823 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 1.866297e-01 | 0.729 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.356297e-01 | 0.628 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 3.065867e-01 | 0.513 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 3.065867e-01 | 0.513 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 3.065867e-01 | 0.513 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 3.065867e-01 | 0.513 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 3.065867e-01 | 0.513 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 4.274924e-01 | 0.369 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 4.274924e-01 | 0.369 | 0 | 0 |
| Defective F8 sulfation at Y1699 | R-HSA-9674519 | 4.274924e-01 | 0.369 | 0 | 0 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 | R-HSA-5083629 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 4.274924e-01 | 0.369 | 0 | 0 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 | R-HSA-5083633 | 4.274924e-01 | 0.369 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 4.274924e-01 | 0.369 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 4.274924e-01 | 0.369 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 4.274924e-01 | 0.369 | 0 | 0 |
| Glycogen storage disease type IV (GBE1) | R-HSA-3878781 | 4.274924e-01 | 0.369 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 4.274924e-01 | 0.369 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 1.726258e-01 | 0.763 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 1.726258e-01 | 0.763 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 1.726258e-01 | 0.763 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 2.149730e-01 | 0.668 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.149730e-01 | 0.668 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.591565e-01 | 0.798 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 2.726801e-01 | 0.564 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 2.726801e-01 | 0.564 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 1.960306e-01 | 0.708 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 1.466317e-01 | 0.834 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 3.570847e-01 | 0.447 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 3.570847e-01 | 0.447 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 3.570847e-01 | 0.447 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.102769e-01 | 0.508 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 3.102769e-01 | 0.508 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 3.102769e-01 | 0.508 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.457361e-01 | 0.610 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 1.662330e-01 | 0.779 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.438716e-01 | 0.613 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 3.480103e-01 | 0.458 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 3.480103e-01 | 0.458 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 3.480103e-01 | 0.458 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 4.061884e-01 | 0.391 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 4.061884e-01 | 0.391 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 4.061884e-01 | 0.391 | 0 | 0 |
| Defective MMACHC causes MAHCC | R-HSA-3359474 | 5.020140e-01 | 0.299 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 5.020140e-01 | 0.299 | 0 | 0 |
| Signalling to STAT3 | R-HSA-198745 | 5.020140e-01 | 0.299 | 0 | 0 |
| Defective GSS causes GSS deficiency | R-HSA-5579006 | 5.020140e-01 | 0.299 | 0 | 0 |
| Defective DPM2 causes DPM2-CDG | R-HSA-4719377 | 5.020140e-01 | 0.299 | 0 | 0 |
| Defective DPM1 causes DPM1-CDG | R-HSA-4717374 | 5.020140e-01 | 0.299 | 0 | 0 |
| Defective DPM3 causes DPM3-CDG | R-HSA-4719360 | 5.020140e-01 | 0.299 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 5.020140e-01 | 0.299 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.650919e-01 | 0.782 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 2.177204e-01 | 0.662 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 2.177204e-01 | 0.662 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 2.144483e-01 | 0.669 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 2.903786e-01 | 0.537 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 2.903786e-01 | 0.537 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 3.855209e-01 | 0.414 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 3.855209e-01 | 0.414 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 3.855209e-01 | 0.414 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 3.855209e-01 | 0.414 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 3.855209e-01 | 0.414 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 2.551259e-01 | 0.593 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 3.251679e-01 | 0.488 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 2.489721e-01 | 0.604 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 2.489721e-01 | 0.604 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 2.489721e-01 | 0.604 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 2.215783e-01 | 0.654 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 1.786618e-01 | 0.748 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 3.142897e-01 | 0.503 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 4.534055e-01 | 0.344 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 2.368007e-01 | 0.626 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 2.368007e-01 | 0.626 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.860117e-01 | 0.730 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 3.040175e-01 | 0.517 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 1.819466e-01 | 0.740 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 3.523246e-01 | 0.453 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 2.455617e-01 | 0.610 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 2.851937e-01 | 0.545 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 3.384945e-01 | 0.470 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 4.224998e-01 | 0.374 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 4.224998e-01 | 0.374 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 4.224998e-01 | 0.374 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 3.989699e-01 | 0.399 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 2.460754e-01 | 0.609 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 3.795776e-01 | 0.421 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 2.676175e-01 | 0.572 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 3.481293e-01 | 0.458 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 3.227121e-01 | 0.491 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 3.227121e-01 | 0.491 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 3.227121e-01 | 0.491 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 4.298496e-01 | 0.367 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 4.298496e-01 | 0.367 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 4.298496e-01 | 0.367 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 4.983954e-01 | 0.302 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.668391e-01 | 0.247 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 5.668391e-01 | 0.247 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 5.668391e-01 | 0.247 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 3.125467e-01 | 0.505 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 3.125467e-01 | 0.505 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 3.656735e-01 | 0.437 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 3.969211e-01 | 0.401 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 4.602898e-01 | 0.337 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 3.174624e-01 | 0.498 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 4.938675e-01 | 0.306 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 4.938675e-01 | 0.306 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.938675e-01 | 0.306 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 4.938675e-01 | 0.306 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 4.023694e-01 | 0.395 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 4.376277e-01 | 0.359 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 5.409381e-01 | 0.267 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 5.409381e-01 | 0.267 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 5.409381e-01 | 0.267 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 4.842850e-01 | 0.315 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 5.192968e-01 | 0.285 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 5.192968e-01 | 0.285 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 4.776199e-01 | 0.321 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 4.776199e-01 | 0.321 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 5.129300e-01 | 0.290 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 5.129300e-01 | 0.290 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 5.129300e-01 | 0.290 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 5.129300e-01 | 0.290 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 5.078522e-01 | 0.294 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 4.999594e-01 | 0.301 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 5.117975e-01 | 0.291 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 5.156581e-01 | 0.288 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 5.156581e-01 | 0.288 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.382909e-01 | 0.269 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 5.382909e-01 | 0.269 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 5.476347e-01 | 0.262 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 5.809082e-01 | 0.236 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 5.809082e-01 | 0.236 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 5.809082e-01 | 0.236 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 5.809082e-01 | 0.236 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 5.809082e-01 | 0.236 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 6.232288e-01 | 0.205 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 6.232288e-01 | 0.205 | 0 | 0 |
| Interleukin-36 pathway | R-HSA-9014826 | 6.232288e-01 | 0.205 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 6.232288e-01 | 0.205 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 5.343455e-01 | 0.272 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 5.537060e-01 | 0.257 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 5.750737e-01 | 0.240 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 5.750737e-01 | 0.240 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 5.750737e-01 | 0.240 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 5.758810e-01 | 0.240 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 5.870658e-01 | 0.231 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 5.970511e-01 | 0.224 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 6.182547e-01 | 0.209 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 6.182547e-01 | 0.209 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 6.182547e-01 | 0.209 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 6.153305e-01 | 0.211 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 6.216401e-01 | 0.206 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 6.216401e-01 | 0.206 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 6.260676e-01 | 0.203 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 6.260676e-01 | 0.203 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 6.260676e-01 | 0.203 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 6.260676e-01 | 0.203 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 6.260676e-01 | 0.203 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 6.388714e-01 | 0.195 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 6.388714e-01 | 0.195 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 6.499180e-01 | 0.187 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 6.499180e-01 | 0.187 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 6.529833e-01 | 0.185 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 6.529833e-01 | 0.185 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 6.529833e-01 | 0.185 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 6.529833e-01 | 0.185 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 6.529833e-01 | 0.185 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 6.529833e-01 | 0.185 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 6.529833e-01 | 0.185 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 6.529833e-01 | 0.185 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 6.529833e-01 | 0.185 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 6.722805e-01 | 0.172 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.722805e-01 | 0.172 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 6.722805e-01 | 0.172 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 6.873229e-01 | 0.163 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 6.776074e-01 | 0.169 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 6.996615e-01 | 0.155 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 6.996615e-01 | 0.155 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 6.746748e-01 | 0.171 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 6.746748e-01 | 0.171 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 6.746748e-01 | 0.171 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 6.974746e-01 | 0.156 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 6.766541e-01 | 0.170 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 6.968686e-01 | 0.157 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 6.851425e-01 | 0.164 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 6.851425e-01 | 0.164 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 6.851425e-01 | 0.164 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 6.851425e-01 | 0.164 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.679845e-01 | 0.775 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 2.057606e-01 | 0.687 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 3.724577e-01 | 0.429 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.434114e-01 | 0.843 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 3.468847e-01 | 0.460 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 2.551259e-01 | 0.593 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 4.591396e-01 | 0.338 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 4.663679e-01 | 0.331 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 4.866988e-01 | 0.313 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 4.866988e-01 | 0.313 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 4.866988e-01 | 0.313 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.839891e-01 | 0.416 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 5.643038e-01 | 0.248 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 1.866297e-01 | 0.729 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 5.250604e-01 | 0.280 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.210553e-01 | 0.493 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 6.216401e-01 | 0.206 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 3.964570e-01 | 0.402 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 2.404300e-01 | 0.619 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.790351e-01 | 0.747 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.650919e-01 | 0.782 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.438716e-01 | 0.613 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 3.678146e-01 | 0.434 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 6.222376e-01 | 0.206 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 6.295085e-01 | 0.201 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.499646e-01 | 0.824 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 6.852809e-01 | 0.164 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 6.585810e-01 | 0.181 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 6.804942e-01 | 0.167 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 3.523246e-01 | 0.453 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 2.285443e-01 | 0.641 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 4.057029e-01 | 0.392 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 6.948918e-01 | 0.158 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 6.103676e-01 | 0.214 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 6.388714e-01 | 0.195 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.438716e-01 | 0.613 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.438716e-01 | 0.613 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.457361e-01 | 0.610 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 2.195330e-01 | 0.659 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 6.522486e-01 | 0.186 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 6.776074e-01 | 0.169 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 2.348301e-01 | 0.629 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 2.149730e-01 | 0.668 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.614563e-01 | 0.792 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 4.224998e-01 | 0.374 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 3.065867e-01 | 0.513 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 3.102769e-01 | 0.508 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 2.746272e-01 | 0.561 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 1.825975e-01 | 0.739 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 3.480103e-01 | 0.458 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 5.409381e-01 | 0.267 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.676314e-01 | 0.776 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 1.891491e-01 | 0.723 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 3.761336e-01 | 0.425 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 3.365675e-01 | 0.473 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 2.823961e-01 | 0.549 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 6.439155e-01 | 0.191 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 3.065867e-01 | 0.513 | 0 | 0 |
| Formation of lateral plate mesoderm | R-HSA-9758920 | 3.065867e-01 | 0.513 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 1.499646e-01 | 0.824 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 3.040175e-01 | 0.517 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 3.523246e-01 | 0.453 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 4.983954e-01 | 0.302 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 4.602898e-01 | 0.337 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 5.409381e-01 | 0.267 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 5.409381e-01 | 0.267 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 5.605605e-01 | 0.251 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 6.722805e-01 | 0.172 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 6.766541e-01 | 0.170 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.142897e-01 | 0.503 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 5.199408e-01 | 0.284 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 5.809082e-01 | 0.236 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 5.275035e-01 | 0.278 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 6.260676e-01 | 0.203 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 1.998452e-01 | 0.699 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 5.144886e-01 | 0.289 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 3.989699e-01 | 0.399 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 1.846572e-01 | 0.734 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 2.043692e-01 | 0.690 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 2.356297e-01 | 0.628 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 1.825975e-01 | 0.739 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 3.480103e-01 | 0.458 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 4.534055e-01 | 0.344 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 4.224998e-01 | 0.374 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 4.983954e-01 | 0.302 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 5.668391e-01 | 0.247 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 5.668391e-01 | 0.247 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 4.818545e-01 | 0.317 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 4.776199e-01 | 0.321 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 4.739651e-01 | 0.324 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 4.999594e-01 | 0.301 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 5.605605e-01 | 0.251 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 6.216401e-01 | 0.206 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 6.499180e-01 | 0.187 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 6.529833e-01 | 0.185 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 6.722805e-01 | 0.172 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 6.746748e-01 | 0.171 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 5.733047e-01 | 0.242 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 4.511732e-01 | 0.346 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 4.511732e-01 | 0.346 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 4.234219e-01 | 0.373 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 6.216401e-01 | 0.206 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.531507e-01 | 0.597 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.384628e-01 | 0.623 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 3.771852e-01 | 0.423 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 6.294607e-01 | 0.201 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 2.361670e-01 | 0.627 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 3.855209e-01 | 0.414 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 6.182547e-01 | 0.209 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 6.216401e-01 | 0.206 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 6.529833e-01 | 0.185 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 4.622056e-01 | 0.335 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 2.943337e-01 | 0.531 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 6.767139e-01 | 0.170 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 6.388714e-01 | 0.195 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 3.187121e-01 | 0.497 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 2.668694e-01 | 0.574 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 3.062663e-01 | 0.514 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 5.278699e-01 | 0.277 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 3.460893e-01 | 0.461 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.838553e-01 | 0.736 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.891491e-01 | 0.723 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 2.593304e-01 | 0.586 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.470904e-01 | 0.262 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 3.245400e-01 | 0.489 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 1.547726e-01 | 0.810 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.553760e-01 | 0.593 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 3.065867e-01 | 0.513 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 4.274924e-01 | 0.369 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 4.274924e-01 | 0.369 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 2.007032e-01 | 0.697 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 4.061884e-01 | 0.391 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 4.061884e-01 | 0.391 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.786618e-01 | 0.748 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.873664e-01 | 0.412 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 4.586868e-01 | 0.338 | 0 | 0 |
| PTK6 Activates STAT3 | R-HSA-8849474 | 6.232288e-01 | 0.205 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 6.232288e-01 | 0.205 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.972502e-01 | 0.303 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 5.632650e-01 | 0.249 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 5.749206e-01 | 0.240 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 6.182547e-01 | 0.209 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 3.474300e-01 | 0.459 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 6.776074e-01 | 0.169 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 5.392205e-01 | 0.268 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 2.726801e-01 | 0.564 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 2.903786e-01 | 0.537 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.402588e-01 | 0.853 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 5.870658e-01 | 0.231 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 3.855209e-01 | 0.414 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.614563e-01 | 0.792 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.614563e-01 | 0.792 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.614563e-01 | 0.792 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.614563e-01 | 0.792 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 6.015441e-01 | 0.221 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 6.513777e-01 | 0.186 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 5.845051e-01 | 0.233 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 6.347278e-01 | 0.197 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 6.008631e-01 | 0.221 | 1 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 3.065867e-01 | 0.513 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 4.983954e-01 | 0.302 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 5.668391e-01 | 0.247 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 5.668391e-01 | 0.247 | 0 | 0 |
| Activation of C3 and C5 | R-HSA-174577 | 6.232288e-01 | 0.205 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 5.868865e-01 | 0.231 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.909773e-01 | 0.228 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 5.310123e-01 | 0.275 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 4.842850e-01 | 0.315 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 2.223383e-01 | 0.653 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 5.295555e-01 | 0.276 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 4.938462e-01 | 0.306 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 5.476347e-01 | 0.262 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 3.855209e-01 | 0.414 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 2.553760e-01 | 0.593 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.825975e-01 | 0.739 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 3.554192e-01 | 0.449 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 4.870120e-01 | 0.312 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 6.182547e-01 | 0.209 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.838553e-01 | 0.736 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 4.891360e-01 | 0.311 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 6.615199e-01 | 0.179 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 4.683569e-01 | 0.329 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 2.758760e-01 | 0.559 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 5.918402e-01 | 0.228 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.328380e-01 | 0.633 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 4.095490e-01 | 0.388 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.982150e-01 | 0.703 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 2.799565e-01 | 0.553 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 5.625852e-01 | 0.250 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 6.023983e-01 | 0.220 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 6.585810e-01 | 0.181 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 2.746272e-01 | 0.561 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 5.470904e-01 | 0.262 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 2.832498e-01 | 0.548 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 1.675446e-01 | 0.776 | 1 | 1 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 6.231897e-01 | 0.205 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.891491e-01 | 0.723 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 4.323572e-01 | 0.364 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.433446e-01 | 0.614 | 0 | 0 |
| Mitochondrial transcription initiation | R-HSA-163282 | 3.418247e-01 | 0.466 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.418247e-01 | 0.466 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.553760e-01 | 0.593 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 2.553760e-01 | 0.593 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 4.274924e-01 | 0.369 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 4.274924e-01 | 0.369 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 4.274924e-01 | 0.369 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 2.443914e-01 | 0.612 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.746272e-01 | 0.561 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 5.020140e-01 | 0.299 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.855209e-01 | 0.414 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 4.534055e-01 | 0.344 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 2.851937e-01 | 0.545 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 4.224998e-01 | 0.374 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 2.605661e-01 | 0.584 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 3.144561e-01 | 0.502 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 4.983954e-01 | 0.302 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 5.668391e-01 | 0.247 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 5.668391e-01 | 0.247 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 3.805862e-01 | 0.420 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 4.388367e-01 | 0.358 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 6.232288e-01 | 0.205 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 6.232288e-01 | 0.205 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 5.295555e-01 | 0.276 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 5.918402e-01 | 0.228 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 6.182547e-01 | 0.209 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 6.216401e-01 | 0.206 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 6.722805e-01 | 0.172 | 0 | 0 |
| Synthesis of dolichyl-phosphate mannose | R-HSA-162699 | 6.722805e-01 | 0.172 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.722805e-01 | 0.172 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 6.766541e-01 | 0.170 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 1.761524e-01 | 0.754 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 5.579774e-01 | 0.253 | 1 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 6.585810e-01 | 0.181 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 5.643745e-01 | 0.248 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 4.586868e-01 | 0.338 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 6.499180e-01 | 0.187 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 3.711756e-01 | 0.430 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 4.057029e-01 | 0.392 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 6.626020e-01 | 0.179 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 6.374068e-01 | 0.196 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 5.856666e-01 | 0.232 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 5.856666e-01 | 0.232 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.298496e-01 | 0.367 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 5.527656e-01 | 0.257 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 6.328870e-01 | 0.199 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 6.616234e-01 | 0.179 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 4.664935e-01 | 0.331 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 6.373319e-01 | 0.196 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 5.228868e-01 | 0.282 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.466317e-01 | 0.834 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.745357e-01 | 0.561 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 3.611153e-01 | 0.442 | 0 | 0 |
| Kinesins | R-HSA-983189 | 3.520941e-01 | 0.453 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 6.486733e-01 | 0.188 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 6.754569e-01 | 0.170 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 6.766541e-01 | 0.170 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 5.696740e-01 | 0.244 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 3.782572e-01 | 0.422 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 6.513777e-01 | 0.186 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.614563e-01 | 0.792 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.757335e-01 | 0.323 | 0 | 0 |
| Inhibition of nitric oxide production | R-HSA-9636249 | 1.547726e-01 | 0.810 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 4.586868e-01 | 0.338 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 5.918402e-01 | 0.228 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 6.722805e-01 | 0.172 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 6.968686e-01 | 0.157 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 2.369118e-01 | 0.625 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 3.867789e-01 | 0.413 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 1.953801e-01 | 0.709 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.926804e-01 | 0.715 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.879961e-01 | 0.541 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 4.177224e-01 | 0.379 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 5.870664e-01 | 0.231 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 3.054314e-01 | 0.515 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 3.054314e-01 | 0.515 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 6.996615e-01 | 0.155 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 6.365811e-01 | 0.196 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 2.404300e-01 | 0.619 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.870120e-01 | 0.312 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.678146e-01 | 0.434 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 6.015441e-01 | 0.221 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 4.556899e-01 | 0.341 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 3.795776e-01 | 0.421 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 3.418289e-01 | 0.466 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 5.788466e-01 | 0.237 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 2.553760e-01 | 0.593 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 1.503897e-01 | 0.823 | 0 | 0 |
| Transcription from mitochondrial promoters | R-HSA-75944 | 4.274924e-01 | 0.369 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 1.790351e-01 | 0.747 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 3.570847e-01 | 0.447 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 3.102769e-01 | 0.508 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 5.020140e-01 | 0.299 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 3.365675e-01 | 0.473 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 3.040175e-01 | 0.517 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 4.586868e-01 | 0.338 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 4.983954e-01 | 0.302 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 5.668391e-01 | 0.247 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 5.668391e-01 | 0.247 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 4.603766e-01 | 0.337 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 4.901469e-01 | 0.310 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 5.409381e-01 | 0.267 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 5.409381e-01 | 0.267 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 5.382909e-01 | 0.269 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 6.015441e-01 | 0.221 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 6.182547e-01 | 0.209 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 6.513777e-01 | 0.186 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 6.559880e-01 | 0.183 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 6.559880e-01 | 0.183 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 6.559880e-01 | 0.183 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 1.998479e-01 | 0.699 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.202473e-01 | 0.657 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 5.870664e-01 | 0.231 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 3.872791e-01 | 0.412 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 4.338447e-01 | 0.363 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 2.356297e-01 | 0.628 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 1.998479e-01 | 0.699 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 4.586868e-01 | 0.338 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 6.144750e-01 | 0.211 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 6.297286e-01 | 0.201 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 6.098301e-01 | 0.215 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 6.974746e-01 | 0.156 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 3.349337e-01 | 0.475 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 6.499180e-01 | 0.187 | 0 | 0 |
| Diseases of Base Excision Repair | R-HSA-9605308 | 6.722805e-01 | 0.172 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 4.591396e-01 | 0.338 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 2.553760e-01 | 0.593 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 4.274924e-01 | 0.369 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 3.570847e-01 | 0.447 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 5.020140e-01 | 0.299 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 5.020140e-01 | 0.299 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 4.534055e-01 | 0.344 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 4.983954e-01 | 0.302 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 4.983954e-01 | 0.302 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 5.278699e-01 | 0.277 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 6.269919e-01 | 0.203 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 6.513777e-01 | 0.186 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 3.142897e-01 | 0.503 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 2.215783e-01 | 0.654 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 6.513777e-01 | 0.186 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 4.338447e-01 | 0.363 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 5.668296e-01 | 0.247 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 6.529833e-01 | 0.185 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 2.149398e-01 | 0.668 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.751593e-01 | 0.757 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 4.754872e-01 | 0.323 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 2.553760e-01 | 0.593 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 3.570847e-01 | 0.447 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 3.481293e-01 | 0.458 | 0 | 0 |
| Interleukin-38 signaling | R-HSA-9007892 | 5.668391e-01 | 0.247 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 5.409381e-01 | 0.267 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 6.722805e-01 | 0.172 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 6.722805e-01 | 0.172 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 3.795776e-01 | 0.421 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 5.592581e-01 | 0.252 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 5.918402e-01 | 0.228 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 6.467272e-01 | 0.189 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 4.624899e-01 | 0.335 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 4.938675e-01 | 0.306 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 5.630232e-01 | 0.249 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 5.643745e-01 | 0.248 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 5.343455e-01 | 0.272 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.901469e-01 | 0.310 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 6.851425e-01 | 0.164 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 6.232288e-01 | 0.205 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 7.018482e-01 | 0.154 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 7.018482e-01 | 0.154 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 7.018482e-01 | 0.154 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 7.018482e-01 | 0.154 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 7.019368e-01 | 0.154 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 7.019368e-01 | 0.154 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 7.135538e-01 | 0.147 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 7.135538e-01 | 0.147 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 7.148126e-01 | 0.146 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 7.148126e-01 | 0.146 | 0 | 0 |
| Synthesis of IPs in the nucleus | R-HSA-1855191 | 7.148126e-01 | 0.146 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 7.148126e-01 | 0.146 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 7.148126e-01 | 0.146 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 7.148126e-01 | 0.146 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 7.148126e-01 | 0.146 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 7.149486e-01 | 0.146 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 7.149486e-01 | 0.146 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 7.149486e-01 | 0.146 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 7.149486e-01 | 0.146 | 0 | 0 |
| Metabolism of ingested MeSeO2H into MeSeH | R-HSA-5263617 | 7.149486e-01 | 0.146 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 7.149486e-01 | 0.146 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 7.149486e-01 | 0.146 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 7.149486e-01 | 0.146 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 7.149486e-01 | 0.146 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 7.149486e-01 | 0.146 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 7.149486e-01 | 0.146 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 7.149486e-01 | 0.146 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 7.149486e-01 | 0.146 | 0 | 0 |
| CREB3 factors activate genes | R-HSA-8874211 | 7.149486e-01 | 0.146 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 7.149486e-01 | 0.146 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 7.179546e-01 | 0.144 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 7.179546e-01 | 0.144 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 7.179546e-01 | 0.144 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 7.188096e-01 | 0.143 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 7.188096e-01 | 0.143 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 7.207706e-01 | 0.142 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 7.207706e-01 | 0.142 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 7.211532e-01 | 0.142 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 7.255159e-01 | 0.139 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 7.255159e-01 | 0.139 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 7.255159e-01 | 0.139 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 7.255159e-01 | 0.139 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 7.255159e-01 | 0.139 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 7.296262e-01 | 0.137 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 7.296262e-01 | 0.137 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 7.311719e-01 | 0.136 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 7.320996e-01 | 0.135 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 7.327230e-01 | 0.135 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.328860e-01 | 0.135 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 7.328860e-01 | 0.135 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.328860e-01 | 0.135 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 7.379375e-01 | 0.132 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 7.420966e-01 | 0.130 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 7.420966e-01 | 0.130 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 7.420966e-01 | 0.130 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 7.420966e-01 | 0.130 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 7.420966e-01 | 0.130 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 7.420966e-01 | 0.130 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 7.420966e-01 | 0.130 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.420966e-01 | 0.130 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 7.420966e-01 | 0.130 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 7.420966e-01 | 0.130 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 7.420966e-01 | 0.130 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 7.420966e-01 | 0.130 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 7.420966e-01 | 0.130 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 7.420966e-01 | 0.130 | 0 | 0 |
| FASTK family proteins regulate processing and stability of mitochondrial RNAs | R-HSA-9837092 | 7.420966e-01 | 0.130 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 7.420966e-01 | 0.130 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 7.420966e-01 | 0.130 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 7.420966e-01 | 0.130 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 7.425287e-01 | 0.129 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 7.425287e-01 | 0.129 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 7.466441e-01 | 0.127 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 7.476863e-01 | 0.126 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 7.502952e-01 | 0.125 | 0 | 0 |
| Glycoprotein hormones | R-HSA-209822 | 7.520637e-01 | 0.124 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 7.520637e-01 | 0.124 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis | R-HSA-9632974 | 7.520637e-01 | 0.124 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 7.520637e-01 | 0.124 | 0 | 0 |
| FGFR3b ligand binding and activation | R-HSA-190371 | 7.520637e-01 | 0.124 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 7.520637e-01 | 0.124 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.520637e-01 | 0.124 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 7.520637e-01 | 0.124 | 0 | 0 |
| Cysteine formation from homocysteine | R-HSA-1614603 | 7.520637e-01 | 0.124 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 7.520637e-01 | 0.124 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 7.520637e-01 | 0.124 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.520637e-01 | 0.124 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.520637e-01 | 0.124 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 7.520637e-01 | 0.124 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.520637e-01 | 0.124 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 7.520637e-01 | 0.124 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 7.520637e-01 | 0.124 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 7.520637e-01 | 0.124 | 0 | 0 |
| Maturation of replicase proteins | R-HSA-9694301 | 7.520637e-01 | 0.124 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 7.568298e-01 | 0.121 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 7.568298e-01 | 0.121 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 7.573094e-01 | 0.121 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 7.579876e-01 | 0.120 | 0 | 0 |
| Protein folding | R-HSA-391251 | 7.589292e-01 | 0.120 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 7.593381e-01 | 0.120 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 7.593381e-01 | 0.120 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 7.668456e-01 | 0.115 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 7.668456e-01 | 0.115 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 7.671128e-01 | 0.115 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 7.671128e-01 | 0.115 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 7.671128e-01 | 0.115 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 7.671128e-01 | 0.115 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 7.671128e-01 | 0.115 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 7.671128e-01 | 0.115 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 7.671128e-01 | 0.115 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 7.671128e-01 | 0.115 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 7.683989e-01 | 0.114 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 7.683989e-01 | 0.114 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 7.683989e-01 | 0.114 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 7.694217e-01 | 0.114 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 7.698922e-01 | 0.114 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 7.732798e-01 | 0.112 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 7.746506e-01 | 0.111 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 7.746506e-01 | 0.111 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 7.810103e-01 | 0.107 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 7.817441e-01 | 0.107 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 7.820026e-01 | 0.107 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 7.825490e-01 | 0.106 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 7.825490e-01 | 0.106 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 7.827381e-01 | 0.106 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 7.843480e-01 | 0.105 | 0 | 0 |
| ALKBH3 mediated reversal of alkylation damage | R-HSA-112126 | 7.843480e-01 | 0.105 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 7.843480e-01 | 0.105 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.843480e-01 | 0.105 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 7.843480e-01 | 0.105 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.843480e-01 | 0.105 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 7.843480e-01 | 0.105 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 7.843480e-01 | 0.105 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.843480e-01 | 0.105 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 7.843480e-01 | 0.105 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 7.843480e-01 | 0.105 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 7.843480e-01 | 0.105 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 7.866176e-01 | 0.104 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 7.877018e-01 | 0.104 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 7.877018e-01 | 0.104 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 7.877018e-01 | 0.104 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 7.899890e-01 | 0.102 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 7.899890e-01 | 0.102 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 7.899890e-01 | 0.102 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.899890e-01 | 0.102 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 7.899890e-01 | 0.102 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 7.899890e-01 | 0.102 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 7.913383e-01 | 0.102 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 7.913724e-01 | 0.102 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.914248e-01 | 0.102 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 7.914248e-01 | 0.102 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 7.927482e-01 | 0.101 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 7.927482e-01 | 0.101 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 7.936967e-01 | 0.100 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 8.043164e-01 | 0.095 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 8.043164e-01 | 0.095 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 8.056494e-01 | 0.094 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 8.056494e-01 | 0.094 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 8.056494e-01 | 0.094 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 8.056494e-01 | 0.094 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.056494e-01 | 0.094 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 8.071817e-01 | 0.093 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.108583e-01 | 0.091 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.108583e-01 | 0.091 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 8.108583e-01 | 0.091 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 8.108583e-01 | 0.091 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.108583e-01 | 0.091 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 8.108583e-01 | 0.091 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 8.108583e-01 | 0.091 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 8.114808e-01 | 0.091 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 8.124301e-01 | 0.090 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 8.124301e-01 | 0.090 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 8.124301e-01 | 0.090 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 8.124301e-01 | 0.090 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 8.124301e-01 | 0.090 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 8.124301e-01 | 0.090 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 8.124301e-01 | 0.090 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 8.124301e-01 | 0.090 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 8.124301e-01 | 0.090 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 8.124301e-01 | 0.090 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 8.181406e-01 | 0.087 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 8.207054e-01 | 0.086 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 8.219544e-01 | 0.085 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 8.219544e-01 | 0.085 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 8.219544e-01 | 0.085 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 8.219544e-01 | 0.085 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.219544e-01 | 0.085 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 8.223010e-01 | 0.085 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 8.223010e-01 | 0.085 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.223010e-01 | 0.085 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.223010e-01 | 0.085 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 8.226295e-01 | 0.085 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 8.231602e-01 | 0.085 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 8.247499e-01 | 0.084 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 8.268579e-01 | 0.083 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 8.298553e-01 | 0.081 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 8.298553e-01 | 0.081 | 0 | 0 |
| PKA activation | R-HSA-163615 | 8.298553e-01 | 0.081 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 8.298553e-01 | 0.081 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.298553e-01 | 0.081 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 8.298553e-01 | 0.081 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 8.338879e-01 | 0.079 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 8.342068e-01 | 0.079 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 8.343840e-01 | 0.079 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 8.357790e-01 | 0.078 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 8.357790e-01 | 0.078 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 8.357790e-01 | 0.078 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 8.368568e-01 | 0.077 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 8.368568e-01 | 0.077 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 8.368568e-01 | 0.077 | 0 | 0 |
| Peptide hormone biosynthesis | R-HSA-209952 | 8.368568e-01 | 0.077 | 0 | 0 |
| TET1,2,3 and TDG demethylate DNA | R-HSA-5221030 | 8.368568e-01 | 0.077 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 8.368568e-01 | 0.077 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 8.368568e-01 | 0.077 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 8.368568e-01 | 0.077 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 8.368568e-01 | 0.077 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 8.368568e-01 | 0.077 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 8.368568e-01 | 0.077 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 8.368568e-01 | 0.077 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 8.368568e-01 | 0.077 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 8.368568e-01 | 0.077 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 8.377187e-01 | 0.077 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 8.377187e-01 | 0.077 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 8.377187e-01 | 0.077 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 8.377187e-01 | 0.077 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.377187e-01 | 0.077 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.392998e-01 | 0.076 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 8.404519e-01 | 0.075 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 8.471137e-01 | 0.072 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 8.471137e-01 | 0.072 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 8.471137e-01 | 0.072 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 8.471137e-01 | 0.072 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 8.486936e-01 | 0.071 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 8.486936e-01 | 0.071 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 8.486936e-01 | 0.071 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 8.486936e-01 | 0.071 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 8.490133e-01 | 0.071 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 8.490133e-01 | 0.071 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 8.491439e-01 | 0.071 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 8.505007e-01 | 0.070 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 8.512262e-01 | 0.070 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 8.517840e-01 | 0.070 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 8.519669e-01 | 0.070 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 8.542861e-01 | 0.068 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 8.576372e-01 | 0.067 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 8.581038e-01 | 0.066 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 8.581038e-01 | 0.066 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 8.581038e-01 | 0.066 | 0 | 0 |
| Hormone ligand-binding receptors | R-HSA-375281 | 8.581038e-01 | 0.066 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 8.581038e-01 | 0.066 | 0 | 0 |
| DAG1 core M3 glycosylations | R-HSA-8932505 | 8.581038e-01 | 0.066 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 8.581038e-01 | 0.066 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 8.581038e-01 | 0.066 | 0 | 0 |
| LGI-ADAM interactions | R-HSA-5682910 | 8.581038e-01 | 0.066 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 8.581038e-01 | 0.066 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 8.581038e-01 | 0.066 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 8.581038e-01 | 0.066 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 8.583302e-01 | 0.066 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 8.607381e-01 | 0.065 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 8.607381e-01 | 0.065 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 8.624900e-01 | 0.064 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 8.627641e-01 | 0.064 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 8.627641e-01 | 0.064 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.627641e-01 | 0.064 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 8.627641e-01 | 0.064 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 8.627641e-01 | 0.064 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 8.638902e-01 | 0.064 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 8.638902e-01 | 0.064 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 8.651108e-01 | 0.063 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 8.651108e-01 | 0.063 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 8.651108e-01 | 0.063 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 8.651108e-01 | 0.063 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 8.651108e-01 | 0.063 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 8.651108e-01 | 0.063 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 8.668017e-01 | 0.062 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 8.704221e-01 | 0.060 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 8.704221e-01 | 0.060 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 8.704221e-01 | 0.060 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 8.765847e-01 | 0.057 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 8.765847e-01 | 0.057 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.765847e-01 | 0.057 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 8.765847e-01 | 0.057 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 8.765847e-01 | 0.057 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 8.765847e-01 | 0.057 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 8.765847e-01 | 0.057 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 8.765847e-01 | 0.057 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 8.765847e-01 | 0.057 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 8.765847e-01 | 0.057 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 8.765847e-01 | 0.057 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 8.765847e-01 | 0.057 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 8.768129e-01 | 0.057 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 8.769325e-01 | 0.057 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 8.769325e-01 | 0.057 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 8.769325e-01 | 0.057 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 8.769325e-01 | 0.057 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 8.769325e-01 | 0.057 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 8.769325e-01 | 0.057 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 8.772153e-01 | 0.057 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.778551e-01 | 0.057 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 8.800156e-01 | 0.056 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 8.800156e-01 | 0.056 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 8.801269e-01 | 0.055 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.812039e-01 | 0.055 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 8.823799e-01 | 0.054 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 8.839883e-01 | 0.054 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 8.839883e-01 | 0.054 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 8.851576e-01 | 0.053 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 8.852449e-01 | 0.053 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.883450e-01 | 0.051 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 8.883450e-01 | 0.051 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.883450e-01 | 0.051 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 8.883450e-01 | 0.051 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 8.883450e-01 | 0.051 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.885813e-01 | 0.051 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 8.897393e-01 | 0.051 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 8.897393e-01 | 0.051 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 8.897393e-01 | 0.051 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 8.903919e-01 | 0.050 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 8.915684e-01 | 0.050 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 8.920598e-01 | 0.050 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 8.920598e-01 | 0.050 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 8.926595e-01 | 0.049 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.926595e-01 | 0.049 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.926595e-01 | 0.049 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.926595e-01 | 0.049 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 8.926595e-01 | 0.049 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 8.926595e-01 | 0.049 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 8.926595e-01 | 0.049 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 8.926595e-01 | 0.049 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 8.926595e-01 | 0.049 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 8.935011e-01 | 0.049 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 8.951104e-01 | 0.048 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 8.976835e-01 | 0.047 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.010336e-01 | 0.045 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 9.010336e-01 | 0.045 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 9.010613e-01 | 0.045 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 9.010613e-01 | 0.045 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.012989e-01 | 0.045 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.012989e-01 | 0.045 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 9.012989e-01 | 0.045 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 9.012989e-01 | 0.045 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.012989e-01 | 0.045 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 9.013523e-01 | 0.045 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.055942e-01 | 0.043 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.056031e-01 | 0.043 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 9.062733e-01 | 0.043 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 9.066414e-01 | 0.043 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 9.066414e-01 | 0.043 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 9.066414e-01 | 0.043 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 9.066414e-01 | 0.043 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 9.066414e-01 | 0.043 | 0 | 0 |
| rRNA modification in the mitochondrion | R-HSA-6793080 | 9.066414e-01 | 0.043 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 9.066414e-01 | 0.043 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 9.079302e-01 | 0.042 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 9.091599e-01 | 0.041 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.093418e-01 | 0.041 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.093418e-01 | 0.041 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 9.103418e-01 | 0.041 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 9.106293e-01 | 0.041 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.117187e-01 | 0.040 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.117187e-01 | 0.040 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 9.129654e-01 | 0.040 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.129654e-01 | 0.040 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.129654e-01 | 0.040 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.129654e-01 | 0.040 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 9.135548e-01 | 0.039 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 9.136702e-01 | 0.039 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 9.136702e-01 | 0.039 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.170239e-01 | 0.038 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.170239e-01 | 0.038 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.175361e-01 | 0.037 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 9.175361e-01 | 0.037 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 9.188027e-01 | 0.037 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 9.188027e-01 | 0.037 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 9.188027e-01 | 0.037 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 9.188027e-01 | 0.037 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 9.188027e-01 | 0.037 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 9.188027e-01 | 0.037 | 0 | 0 |
| Vitamin B2 (riboflavin) metabolism | R-HSA-196843 | 9.188027e-01 | 0.037 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 9.188027e-01 | 0.037 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 9.188027e-01 | 0.037 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 9.188027e-01 | 0.037 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 9.188027e-01 | 0.037 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 9.188027e-01 | 0.037 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 9.188027e-01 | 0.037 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 9.188027e-01 | 0.037 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.198258e-01 | 0.036 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 9.205649e-01 | 0.036 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.210995e-01 | 0.036 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 9.210995e-01 | 0.036 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 9.210995e-01 | 0.036 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.210995e-01 | 0.036 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.210995e-01 | 0.036 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 9.221482e-01 | 0.035 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 9.221482e-01 | 0.035 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 9.224529e-01 | 0.035 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.232686e-01 | 0.035 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.241183e-01 | 0.034 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 9.243474e-01 | 0.034 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.243474e-01 | 0.034 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 9.243474e-01 | 0.034 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 9.243474e-01 | 0.034 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.243474e-01 | 0.034 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 9.244393e-01 | 0.034 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 9.244393e-01 | 0.034 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 9.262036e-01 | 0.033 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 9.279566e-01 | 0.032 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 9.280841e-01 | 0.032 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.280841e-01 | 0.032 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 9.293805e-01 | 0.032 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 9.293805e-01 | 0.032 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 9.293805e-01 | 0.032 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 9.293805e-01 | 0.032 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 9.293805e-01 | 0.032 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 9.293805e-01 | 0.032 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 9.293805e-01 | 0.032 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 9.293805e-01 | 0.032 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 9.293805e-01 | 0.032 | 0 | 0 |
| Transport and metabolism of PAPS | R-HSA-174362 | 9.293805e-01 | 0.032 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 9.293805e-01 | 0.032 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 9.293805e-01 | 0.032 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.295352e-01 | 0.032 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.295352e-01 | 0.032 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.295352e-01 | 0.032 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.295352e-01 | 0.032 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.295352e-01 | 0.032 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.295352e-01 | 0.032 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 9.295352e-01 | 0.032 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.306622e-01 | 0.031 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 9.308403e-01 | 0.031 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.315081e-01 | 0.031 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.315081e-01 | 0.031 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 9.342848e-01 | 0.030 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 9.366914e-01 | 0.028 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.366914e-01 | 0.028 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 9.366914e-01 | 0.028 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 9.371127e-01 | 0.028 | 0 | 0 |
| Attachment of bacteria to epithelial cells | R-HSA-9638630 | 9.371127e-01 | 0.028 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 9.378378e-01 | 0.028 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 9.380396e-01 | 0.028 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.380396e-01 | 0.028 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.380396e-01 | 0.028 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 9.385808e-01 | 0.028 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 9.385808e-01 | 0.028 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 9.385808e-01 | 0.028 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 9.385808e-01 | 0.028 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.385808e-01 | 0.028 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 9.385808e-01 | 0.028 | 0 | 0 |
| Mineralocorticoid biosynthesis | R-HSA-193993 | 9.385808e-01 | 0.028 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 9.385808e-01 | 0.028 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 9.385808e-01 | 0.028 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 9.385808e-01 | 0.028 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 9.409259e-01 | 0.026 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 9.424676e-01 | 0.026 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.427114e-01 | 0.026 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 9.439124e-01 | 0.025 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 9.439124e-01 | 0.025 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 9.439124e-01 | 0.025 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 9.439124e-01 | 0.025 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 9.439124e-01 | 0.025 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.439124e-01 | 0.025 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.439124e-01 | 0.025 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.439124e-01 | 0.025 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.439907e-01 | 0.025 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.443805e-01 | 0.025 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 9.447433e-01 | 0.025 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 9.447951e-01 | 0.025 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 9.449491e-01 | 0.025 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 9.465830e-01 | 0.024 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 9.465830e-01 | 0.024 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 9.465830e-01 | 0.024 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 9.465830e-01 | 0.024 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 9.465830e-01 | 0.024 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.465830e-01 | 0.024 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 9.465830e-01 | 0.024 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.472956e-01 | 0.024 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.478890e-01 | 0.023 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.500083e-01 | 0.022 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.500083e-01 | 0.022 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.500083e-01 | 0.022 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 9.500083e-01 | 0.022 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.517835e-01 | 0.021 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 9.520272e-01 | 0.021 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 9.535430e-01 | 0.021 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 9.535430e-01 | 0.021 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 9.535430e-01 | 0.021 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 9.535430e-01 | 0.021 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 9.535430e-01 | 0.021 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 9.535430e-01 | 0.021 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.543239e-01 | 0.020 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 9.543318e-01 | 0.020 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.543318e-01 | 0.020 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 9.548021e-01 | 0.020 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 9.554015e-01 | 0.020 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.554683e-01 | 0.020 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.554683e-01 | 0.020 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 9.554683e-01 | 0.020 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.558111e-01 | 0.020 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.562627e-01 | 0.019 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 9.584870e-01 | 0.018 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 9.584870e-01 | 0.018 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 9.588051e-01 | 0.018 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 9.588051e-01 | 0.018 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 9.595964e-01 | 0.018 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 9.595964e-01 | 0.018 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 9.595964e-01 | 0.018 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 9.595964e-01 | 0.018 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 9.595964e-01 | 0.018 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 9.595964e-01 | 0.018 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.595964e-01 | 0.018 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 9.595964e-01 | 0.018 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 9.599070e-01 | 0.018 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.628645e-01 | 0.016 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.628645e-01 | 0.016 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.628645e-01 | 0.016 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.628645e-01 | 0.016 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.628645e-01 | 0.016 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.629584e-01 | 0.016 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.638758e-01 | 0.016 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 9.640915e-01 | 0.016 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.647241e-01 | 0.016 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 9.648614e-01 | 0.016 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.648614e-01 | 0.016 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 9.648614e-01 | 0.016 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 9.648614e-01 | 0.016 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 9.648614e-01 | 0.016 | 0 | 0 |
| Transport of nucleotide sugars | R-HSA-727802 | 9.648614e-01 | 0.016 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 9.648614e-01 | 0.016 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 9.648614e-01 | 0.016 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 9.648614e-01 | 0.016 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.648614e-01 | 0.016 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.651639e-01 | 0.015 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 9.653600e-01 | 0.015 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 9.656973e-01 | 0.015 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 9.658894e-01 | 0.015 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 9.660889e-01 | 0.015 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.661185e-01 | 0.015 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.665452e-01 | 0.015 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 9.665452e-01 | 0.015 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 9.665452e-01 | 0.015 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.665452e-01 | 0.015 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.665452e-01 | 0.015 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 9.670869e-01 | 0.015 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 9.674659e-01 | 0.014 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.682274e-01 | 0.014 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.686283e-01 | 0.014 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.686283e-01 | 0.014 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 9.686283e-01 | 0.014 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 9.694406e-01 | 0.013 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.694406e-01 | 0.013 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 9.694406e-01 | 0.013 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.694406e-01 | 0.013 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.698794e-01 | 0.013 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.698794e-01 | 0.013 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.698794e-01 | 0.013 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 9.698794e-01 | 0.013 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.698794e-01 | 0.013 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.701970e-01 | 0.013 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 9.704201e-01 | 0.013 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 9.704201e-01 | 0.013 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 9.713862e-01 | 0.013 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 9.717052e-01 | 0.012 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 9.721143e-01 | 0.012 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 9.721143e-01 | 0.012 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 9.721143e-01 | 0.012 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.721143e-01 | 0.012 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.721143e-01 | 0.012 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.728975e-01 | 0.012 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.729548e-01 | 0.012 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.733035e-01 | 0.012 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 9.733035e-01 | 0.012 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 9.734233e-01 | 0.012 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.734233e-01 | 0.012 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 9.734233e-01 | 0.012 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 9.734233e-01 | 0.012 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 9.734233e-01 | 0.012 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.734233e-01 | 0.012 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.737388e-01 | 0.012 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 9.752248e-01 | 0.011 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 9.752248e-01 | 0.011 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.752248e-01 | 0.011 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 9.752248e-01 | 0.011 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 9.752248e-01 | 0.011 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.752248e-01 | 0.011 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.752248e-01 | 0.011 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 9.760272e-01 | 0.011 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 9.765462e-01 | 0.010 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 9.768871e-01 | 0.010 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 9.768871e-01 | 0.010 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 9.768871e-01 | 0.010 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.768871e-01 | 0.010 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.768871e-01 | 0.010 | 0 | 0 |
| Androgen biosynthesis | R-HSA-193048 | 9.768871e-01 | 0.010 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.768871e-01 | 0.010 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 9.779984e-01 | 0.010 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.779984e-01 | 0.010 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.779984e-01 | 0.010 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 9.779984e-01 | 0.010 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.779984e-01 | 0.010 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.780939e-01 | 0.010 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 9.780939e-01 | 0.010 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.780939e-01 | 0.010 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 9.780939e-01 | 0.010 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 9.780939e-01 | 0.010 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 9.798596e-01 | 0.009 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 9.798997e-01 | 0.009 | 0 | 0 |
| Reactions specific to the complex N-glycan synthesis pathway | R-HSA-975578 | 9.798997e-01 | 0.009 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.798997e-01 | 0.009 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.798997e-01 | 0.009 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.798997e-01 | 0.009 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 9.798997e-01 | 0.009 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 9.804044e-01 | 0.009 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 9.804044e-01 | 0.009 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.804701e-01 | 0.009 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.804701e-01 | 0.009 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.804701e-01 | 0.009 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.804701e-01 | 0.009 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 9.812700e-01 | 0.008 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 9.814065e-01 | 0.008 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 9.825197e-01 | 0.008 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 9.825197e-01 | 0.008 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.825197e-01 | 0.008 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.825197e-01 | 0.008 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.825197e-01 | 0.008 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 9.826714e-01 | 0.008 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.826714e-01 | 0.008 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 9.826714e-01 | 0.008 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 9.826714e-01 | 0.008 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.826714e-01 | 0.008 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 9.834987e-01 | 0.007 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.834987e-01 | 0.007 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.837463e-01 | 0.007 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 9.841452e-01 | 0.007 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.841831e-01 | 0.007 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.844032e-01 | 0.007 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.844032e-01 | 0.007 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.844032e-01 | 0.007 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 9.846309e-01 | 0.007 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.846309e-01 | 0.007 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.846309e-01 | 0.007 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.846309e-01 | 0.007 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 9.847983e-01 | 0.007 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.847983e-01 | 0.007 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.847983e-01 | 0.007 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.847983e-01 | 0.007 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.850754e-01 | 0.007 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.850754e-01 | 0.007 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.852086e-01 | 0.006 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 9.854512e-01 | 0.006 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 9.854759e-01 | 0.006 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 9.857792e-01 | 0.006 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 9.857792e-01 | 0.006 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 9.863741e-01 | 0.006 | 0 | 0 |
| Depurination | R-HSA-73927 | 9.863741e-01 | 0.006 | 0 | 0 |
| Biofilm formation | R-HSA-9931953 | 9.863741e-01 | 0.006 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 9.863741e-01 | 0.006 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.865084e-01 | 0.006 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.865462e-01 | 0.006 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.867801e-01 | 0.006 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.867801e-01 | 0.006 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.868123e-01 | 0.006 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.877708e-01 | 0.005 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.878098e-01 | 0.005 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.878098e-01 | 0.005 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.879241e-01 | 0.005 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.879241e-01 | 0.005 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.879241e-01 | 0.005 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.883712e-01 | 0.005 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.885036e-01 | 0.005 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.885036e-01 | 0.005 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.885036e-01 | 0.005 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.885036e-01 | 0.005 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 9.885036e-01 | 0.005 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.893017e-01 | 0.005 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.893017e-01 | 0.005 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.894063e-01 | 0.005 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 9.897671e-01 | 0.004 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.897671e-01 | 0.004 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 9.899058e-01 | 0.004 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.899058e-01 | 0.004 | 0 | 0 |
| Cobalamin (Cbl) metabolism | R-HSA-9759218 | 9.900025e-01 | 0.004 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.900025e-01 | 0.004 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 9.900025e-01 | 0.004 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.900625e-01 | 0.004 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 9.903836e-01 | 0.004 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.905255e-01 | 0.004 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 9.905844e-01 | 0.004 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 9.906267e-01 | 0.004 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.911570e-01 | 0.004 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.911624e-01 | 0.004 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 9.913060e-01 | 0.004 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 9.913060e-01 | 0.004 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 9.913060e-01 | 0.004 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.913060e-01 | 0.004 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 9.913781e-01 | 0.004 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.916120e-01 | 0.004 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.916120e-01 | 0.004 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 9.916513e-01 | 0.004 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.924396e-01 | 0.003 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.924396e-01 | 0.003 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.925764e-01 | 0.003 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.926167e-01 | 0.003 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.934255e-01 | 0.003 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 9.934255e-01 | 0.003 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.934255e-01 | 0.003 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.934320e-01 | 0.003 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 9.934417e-01 | 0.003 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.937955e-01 | 0.003 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.937955e-01 | 0.003 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 9.938728e-01 | 0.003 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.941379e-01 | 0.003 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.941908e-01 | 0.003 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 9.941908e-01 | 0.003 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.941908e-01 | 0.003 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.942564e-01 | 0.003 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 9.942829e-01 | 0.002 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.942829e-01 | 0.002 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.943877e-01 | 0.002 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.946739e-01 | 0.002 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.948606e-01 | 0.002 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 9.948634e-01 | 0.002 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.948634e-01 | 0.002 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 9.948634e-01 | 0.002 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 9.949623e-01 | 0.002 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.950285e-01 | 0.002 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.952068e-01 | 0.002 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.953218e-01 | 0.002 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 9.953673e-01 | 0.002 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.954008e-01 | 0.002 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.955813e-01 | 0.002 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 9.957793e-01 | 0.002 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.958022e-01 | 0.002 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.958230e-01 | 0.002 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.958230e-01 | 0.002 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.959874e-01 | 0.002 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 9.961008e-01 | 0.002 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.961400e-01 | 0.002 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 9.961704e-01 | 0.002 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.962408e-01 | 0.002 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.962408e-01 | 0.002 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 9.962719e-01 | 0.002 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.964549e-01 | 0.002 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.964549e-01 | 0.002 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 9.966737e-01 | 0.001 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.967311e-01 | 0.001 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.968688e-01 | 0.001 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.970988e-01 | 0.001 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.971575e-01 | 0.001 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.971575e-01 | 0.001 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.971593e-01 | 0.001 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.971593e-01 | 0.001 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 9.972929e-01 | 0.001 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.973411e-01 | 0.001 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.973773e-01 | 0.001 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.974738e-01 | 0.001 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 9.975590e-01 | 0.001 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.977325e-01 | 0.001 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.978508e-01 | 0.001 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.978508e-01 | 0.001 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.979653e-01 | 0.001 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 9.980066e-01 | 0.001 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.980456e-01 | 0.001 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 9.980628e-01 | 0.001 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.980989e-01 | 0.001 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 9.981284e-01 | 0.001 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.981284e-01 | 0.001 | 0 | 0 |
| tRNA processing in the mitochondrion | R-HSA-6785470 | 9.981312e-01 | 0.001 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.981312e-01 | 0.001 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.981312e-01 | 0.001 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.983333e-01 | 0.001 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.983511e-01 | 0.001 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.983750e-01 | 0.001 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.983750e-01 | 0.001 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.985026e-01 | 0.001 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.985207e-01 | 0.001 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 9.985871e-01 | 0.001 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.985871e-01 | 0.001 | 0 | 0 |
| N-glycan antennae elongation in the medial/trans-Golgi | R-HSA-975576 | 9.985871e-01 | 0.001 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.985871e-01 | 0.001 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.986955e-01 | 0.001 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.987844e-01 | 0.001 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.988499e-01 | 0.000 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.989318e-01 | 0.000 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.991736e-01 | 0.000 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.991924e-01 | 0.000 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.992128e-01 | 0.000 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.992565e-01 | 0.000 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.992823e-01 | 0.000 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 9.992970e-01 | 0.000 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.992978e-01 | 0.000 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.992978e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.993065e-01 | 0.000 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.993131e-01 | 0.000 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.993895e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.994620e-01 | 0.000 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.994655e-01 | 0.000 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.994692e-01 | 0.000 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.994692e-01 | 0.000 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.994692e-01 | 0.000 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.995385e-01 | 0.000 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.995785e-01 | 0.000 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.995987e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.996770e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.996770e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.997158e-01 | 0.000 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 9.997176e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.997441e-01 | 0.000 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.997662e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.998065e-01 | 0.000 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.998065e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.998246e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.998318e-01 | 0.000 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.998493e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.998493e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.998504e-01 | 0.000 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 9.998612e-01 | 0.000 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 9.999018e-01 | 0.000 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.999041e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999215e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.999215e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.999250e-01 | 0.000 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.999252e-01 | 0.000 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.999252e-01 | 0.000 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.999512e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.999573e-01 | 0.000 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.999582e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999593e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999614e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999640e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.999641e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999716e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999719e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.999719e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.999756e-01 | 0.000 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 9.999831e-01 | 0.000 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.999835e-01 | 0.000 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.999846e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.999861e-01 | 0.000 | 0 | 0 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 9.999895e-01 | 0.000 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.999908e-01 | 0.000 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.999908e-01 | 0.000 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.999914e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.999934e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999937e-01 | 0.000 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.999940e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.999948e-01 | 0.000 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.999961e-01 | 0.000 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.999966e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999974e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999983e-01 | 0.000 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.999985e-01 | 0.000 | 0 | 0 |
| Classical antibody-mediated complement activation | R-HSA-173623 | 9.999987e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999992e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999994e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999996e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999996e-01 | 0.000 | 0 | 0 |
| Initial triggering of complement | R-HSA-166663 | 9.999996e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999997e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999997e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999998e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.999998e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999998e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999998e-01 | 0.000 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.999999e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999999e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999999e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999999e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999999e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999999e-01 | 0.000 | 0 | 0 |
| Creation of C4 and C2 activators | R-HSA-166786 | 9.999999e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999999e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.999999e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.999999e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.999999e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 1.000000e+00 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 1.000000e+00 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 1.000000e+00 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 1.000000e+00 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.000000e+00 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 1.000000e+00 | 0.000 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 1.000000e+00 | -0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | -0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 2.220446e-16 | 15.654 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.332268e-15 | 14.875 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.998401e-15 | 14.699 | 0 | 0 |
| M Phase | R-HSA-68886 | 6.106227e-15 | 14.214 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.743050e-14 | 13.759 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.668665e-13 | 12.778 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 9.960810e-12 | 11.002 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.235345e-11 | 10.908 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 3.704936e-11 | 10.431 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 7.451562e-11 | 10.128 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 9.001144e-11 | 10.046 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.485992e-10 | 9.828 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 2.494537e-10 | 9.603 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 6.648505e-10 | 9.177 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 7.801384e-10 | 9.108 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 8.507804e-10 | 9.070 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.082662e-09 | 8.966 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.172084e-09 | 8.931 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.591500e-09 | 8.798 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.683898e-09 | 8.774 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 4.845626e-09 | 8.315 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 8.274339e-09 | 8.082 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 8.565252e-09 | 8.067 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.008627e-08 | 7.996 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.086784e-08 | 7.964 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.460295e-08 | 7.836 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.422816e-08 | 7.847 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.584662e-08 | 7.800 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 2.424986e-08 | 7.615 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 2.425236e-08 | 7.615 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 5.271860e-08 | 7.278 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 5.040073e-08 | 7.298 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 5.712389e-08 | 7.243 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 6.040520e-08 | 7.219 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 7.552895e-08 | 7.122 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 8.888950e-08 | 7.051 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 9.266066e-08 | 7.033 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 9.613579e-08 | 7.017 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 9.647756e-08 | 7.016 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 1.102353e-07 | 6.958 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.248757e-07 | 6.904 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.292343e-07 | 6.889 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.504654e-07 | 6.823 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.792946e-07 | 6.746 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.875150e-07 | 6.727 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.875150e-07 | 6.727 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 2.224775e-07 | 6.653 | 1 | 0 |
| Nervous system development | R-HSA-9675108 | 2.199173e-07 | 6.658 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 3.203558e-07 | 6.494 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 3.701488e-07 | 6.432 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 3.788625e-07 | 6.422 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 4.108145e-07 | 6.386 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 4.542567e-07 | 6.343 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 4.849992e-07 | 6.314 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 6.664820e-07 | 6.176 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 6.702518e-07 | 6.174 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 7.129192e-07 | 6.147 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 8.865556e-07 | 6.052 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.119078e-06 | 5.951 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.266662e-06 | 5.897 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.266662e-06 | 5.897 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.277167e-06 | 5.894 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 1.445411e-06 | 5.840 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.486988e-06 | 5.828 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.508594e-06 | 5.821 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 1.620053e-06 | 5.790 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 1.938377e-06 | 5.713 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 2.281010e-06 | 5.642 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 2.359007e-06 | 5.627 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 2.629811e-06 | 5.580 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 3.027166e-06 | 5.519 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 3.266033e-06 | 5.486 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 3.308304e-06 | 5.480 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 3.337393e-06 | 5.477 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 4.176345e-06 | 5.379 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 4.619104e-06 | 5.335 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 4.993940e-06 | 5.302 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 4.993940e-06 | 5.302 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.519007e-06 | 5.258 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 6.407757e-06 | 5.193 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 6.759894e-06 | 5.170 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 6.845997e-06 | 5.165 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 7.262662e-06 | 5.139 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 7.262662e-06 | 5.139 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 7.274070e-06 | 5.138 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 8.502662e-06 | 5.070 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 8.502662e-06 | 5.070 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 9.006207e-06 | 5.045 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 9.682689e-06 | 5.014 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.134580e-05 | 4.945 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.199905e-05 | 4.921 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.466689e-05 | 4.834 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.471436e-05 | 4.832 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.526518e-05 | 4.816 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.589607e-05 | 4.799 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.645499e-05 | 4.784 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.783202e-05 | 4.749 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.783202e-05 | 4.749 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.783202e-05 | 4.749 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.783202e-05 | 4.749 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.747909e-05 | 4.757 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 2.024799e-05 | 4.694 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.235097e-05 | 4.651 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 2.646444e-05 | 4.577 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 2.850334e-05 | 4.545 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.119754e-05 | 4.506 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 3.442405e-05 | 4.463 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 3.442405e-05 | 4.463 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 3.948100e-05 | 4.404 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 4.280188e-05 | 4.369 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 4.337169e-05 | 4.363 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.337169e-05 | 4.363 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 4.394436e-05 | 4.357 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 4.676196e-05 | 4.330 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 4.962575e-05 | 4.304 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 5.073769e-05 | 4.295 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 5.097572e-05 | 4.293 | 0 | 0 |
| Protein folding | R-HSA-391251 | 5.363989e-05 | 4.271 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 5.629088e-05 | 4.250 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 5.694226e-05 | 4.245 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 5.984936e-05 | 4.223 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 6.114833e-05 | 4.214 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 6.297523e-05 | 4.201 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 6.318204e-05 | 4.199 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 6.552317e-05 | 4.184 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 6.648199e-05 | 4.177 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 7.023720e-05 | 4.153 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 7.245633e-05 | 4.140 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 7.373662e-05 | 4.132 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 7.373662e-05 | 4.132 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 7.591803e-05 | 4.120 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 7.778622e-05 | 4.109 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 7.903689e-05 | 4.102 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 8.475954e-05 | 4.072 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 8.315145e-05 | 4.080 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 8.571103e-05 | 4.067 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 8.571103e-05 | 4.067 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 9.242884e-05 | 4.034 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 9.242884e-05 | 4.034 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.031489e-04 | 3.987 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.031489e-04 | 3.987 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.155896e-04 | 3.937 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.348857e-04 | 3.870 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 1.376967e-04 | 3.861 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.386912e-04 | 3.858 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.645595e-04 | 3.784 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.760276e-04 | 3.754 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 1.760276e-04 | 3.754 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 1.773187e-04 | 3.751 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.822151e-04 | 3.739 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.907591e-04 | 3.720 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.907591e-04 | 3.720 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 2.057917e-04 | 3.687 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.080895e-04 | 3.682 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 2.153643e-04 | 3.667 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 2.153643e-04 | 3.667 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.267671e-04 | 3.644 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 2.692641e-04 | 3.570 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 2.529069e-04 | 3.597 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.677460e-04 | 3.572 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 2.856818e-04 | 3.544 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 2.896195e-04 | 3.538 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 2.981974e-04 | 3.525 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 3.003814e-04 | 3.522 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.109784e-04 | 3.507 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 3.354144e-04 | 3.474 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 3.441488e-04 | 3.463 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 3.570834e-04 | 3.447 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.570834e-04 | 3.447 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.604929e-04 | 3.443 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 3.614359e-04 | 3.442 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 3.683101e-04 | 3.434 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 4.027801e-04 | 3.395 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 4.040794e-04 | 3.394 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 4.060757e-04 | 3.391 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 4.463518e-04 | 3.350 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 4.478817e-04 | 3.349 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 4.478817e-04 | 3.349 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 4.642721e-04 | 3.333 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 4.664303e-04 | 3.331 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 4.703447e-04 | 3.328 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 4.759089e-04 | 3.322 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 5.022475e-04 | 3.299 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 5.189732e-04 | 3.285 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 5.268381e-04 | 3.278 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.514385e-04 | 3.259 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 5.624121e-04 | 3.250 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 5.749771e-04 | 3.240 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 5.846063e-04 | 3.233 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 6.063330e-04 | 3.217 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 6.919743e-04 | 3.160 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 7.057051e-04 | 3.151 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 7.110166e-04 | 3.148 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 7.034859e-04 | 3.153 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 7.176581e-04 | 3.144 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 7.054246e-04 | 3.152 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 6.648196e-04 | 3.177 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 7.589013e-04 | 3.120 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 7.589013e-04 | 3.120 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.006036e-04 | 3.097 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 8.037669e-04 | 3.095 | 0 | 0 |
| Kinesins | R-HSA-983189 | 8.735872e-04 | 3.059 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 8.744155e-04 | 3.058 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 8.758016e-04 | 3.058 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 9.080566e-04 | 3.042 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 9.337942e-04 | 3.030 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 9.387637e-04 | 3.027 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 9.387637e-04 | 3.027 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 9.967997e-04 | 3.001 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.035422e-03 | 2.985 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.159298e-03 | 2.936 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 1.117151e-03 | 2.952 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.117151e-03 | 2.952 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 1.134129e-03 | 2.945 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.063231e-03 | 2.973 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 1.025923e-03 | 2.989 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 1.194111e-03 | 2.923 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 1.194111e-03 | 2.923 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 1.194111e-03 | 2.923 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.195407e-03 | 2.922 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 1.200346e-03 | 2.921 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 1.267221e-03 | 2.897 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.327670e-03 | 2.877 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 1.393326e-03 | 2.856 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 1.393326e-03 | 2.856 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.393326e-03 | 2.856 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.495520e-03 | 2.825 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 1.523870e-03 | 2.817 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.563760e-03 | 2.806 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 1.563760e-03 | 2.806 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 1.563760e-03 | 2.806 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.568636e-03 | 2.804 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.606386e-03 | 2.794 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.671080e-03 | 2.777 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 1.671080e-03 | 2.777 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 1.708971e-03 | 2.767 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.744677e-03 | 2.758 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.756370e-03 | 2.755 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.810266e-03 | 2.742 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 1.852778e-03 | 2.732 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 1.852778e-03 | 2.732 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 2.256214e-03 | 2.647 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 2.352946e-03 | 2.628 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 2.344974e-03 | 2.630 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.344817e-03 | 2.630 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 2.442390e-03 | 2.612 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.367734e-03 | 2.626 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 2.153501e-03 | 2.667 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 2.402765e-03 | 2.619 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 2.442390e-03 | 2.612 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 2.455943e-03 | 2.610 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.498079e-03 | 2.602 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 2.566553e-03 | 2.591 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.582033e-03 | 2.588 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 2.589310e-03 | 2.587 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 2.649374e-03 | 2.577 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 2.667621e-03 | 2.574 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 2.667621e-03 | 2.574 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 2.667621e-03 | 2.574 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.667621e-03 | 2.574 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 2.682073e-03 | 2.572 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 2.704908e-03 | 2.568 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 2.704908e-03 | 2.568 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 2.704908e-03 | 2.568 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 2.774354e-03 | 2.557 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 2.777261e-03 | 2.556 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 2.828607e-03 | 2.548 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 2.856220e-03 | 2.544 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 2.868639e-03 | 2.542 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 2.896779e-03 | 2.538 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 2.970232e-03 | 2.527 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 3.004046e-03 | 2.522 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 3.024418e-03 | 2.519 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 3.024418e-03 | 2.519 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 3.024418e-03 | 2.519 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.039607e-03 | 2.517 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.039607e-03 | 2.517 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 3.251591e-03 | 2.488 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 3.271100e-03 | 2.485 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.285637e-03 | 2.483 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 3.295753e-03 | 2.482 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 3.310432e-03 | 2.480 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 3.310432e-03 | 2.480 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 3.781325e-03 | 2.422 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 3.781325e-03 | 2.422 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 3.703744e-03 | 2.431 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 4.332997e-03 | 2.363 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 4.312745e-03 | 2.365 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 3.875249e-03 | 2.412 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 3.953578e-03 | 2.403 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 3.953578e-03 | 2.403 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 3.781325e-03 | 2.422 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 4.312745e-03 | 2.365 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 4.352541e-03 | 2.361 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 4.073503e-03 | 2.390 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 4.369395e-03 | 2.360 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 4.396606e-03 | 2.357 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 4.404229e-03 | 2.356 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 4.649270e-03 | 2.333 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 4.649270e-03 | 2.333 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 4.920909e-03 | 2.308 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 5.034384e-03 | 2.298 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 5.046196e-03 | 2.297 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 5.073685e-03 | 2.295 | 1 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 5.202289e-03 | 2.284 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 5.202289e-03 | 2.284 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 5.377428e-03 | 2.269 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 5.706121e-03 | 2.244 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 5.746905e-03 | 2.241 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 5.750355e-03 | 2.240 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 5.750355e-03 | 2.240 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 5.769512e-03 | 2.239 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 5.810576e-03 | 2.236 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 5.864373e-03 | 2.232 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 5.885532e-03 | 2.230 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 6.012145e-03 | 2.221 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 6.077678e-03 | 2.216 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 6.077678e-03 | 2.216 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 6.129049e-03 | 2.213 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 6.230820e-03 | 2.205 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 6.230820e-03 | 2.205 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 6.250114e-03 | 2.204 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 6.562657e-03 | 2.183 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 6.687957e-03 | 2.175 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 6.892492e-03 | 2.162 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 6.892492e-03 | 2.162 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 8.459359e-03 | 2.073 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 8.459359e-03 | 2.073 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 7.417877e-03 | 2.130 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 7.990039e-03 | 2.097 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 7.990039e-03 | 2.097 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 7.914452e-03 | 2.102 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 8.687345e-03 | 2.061 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 8.075401e-03 | 2.093 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 7.101946e-03 | 2.149 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 8.289618e-03 | 2.081 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 7.914452e-03 | 2.102 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 8.323243e-03 | 2.080 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 8.456255e-03 | 2.073 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 7.519197e-03 | 2.124 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 7.532330e-03 | 2.123 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 7.990039e-03 | 2.097 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 8.459359e-03 | 2.073 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 8.086414e-03 | 2.092 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 8.709178e-03 | 2.060 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 8.898783e-03 | 2.051 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 8.980641e-03 | 2.047 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 8.980641e-03 | 2.047 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 8.999044e-03 | 2.046 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 9.137040e-03 | 2.039 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 9.486300e-03 | 2.023 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.628927e-03 | 2.016 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 9.965125e-03 | 2.002 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 1.009673e-02 | 1.996 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.023727e-02 | 1.990 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.024722e-02 | 1.989 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.055381e-02 | 1.977 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.063455e-02 | 1.973 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.063455e-02 | 1.973 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.063455e-02 | 1.973 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.063455e-02 | 1.973 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.104585e-02 | 1.957 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.104585e-02 | 1.957 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.134332e-02 | 1.945 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 1.145935e-02 | 1.941 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.154473e-02 | 1.938 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 1.194199e-02 | 1.923 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 1.194947e-02 | 1.923 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.194947e-02 | 1.923 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 1.202283e-02 | 1.920 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.204140e-02 | 1.919 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.204140e-02 | 1.919 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.211527e-02 | 1.917 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.235774e-02 | 1.908 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.237735e-02 | 1.907 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.291246e-02 | 1.889 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 1.307833e-02 | 1.883 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 1.307833e-02 | 1.883 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.329851e-02 | 1.876 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.380264e-02 | 1.860 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 1.384419e-02 | 1.859 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 1.384419e-02 | 1.859 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.396492e-02 | 1.855 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.404812e-02 | 1.852 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 1.421425e-02 | 1.847 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 1.474237e-02 | 1.831 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 1.550245e-02 | 1.810 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 1.550536e-02 | 1.810 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.599707e-02 | 1.796 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 1.605604e-02 | 1.794 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.610992e-02 | 1.793 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.148452e-02 | 1.668 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.148452e-02 | 1.668 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.148452e-02 | 1.668 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.148452e-02 | 1.668 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.148452e-02 | 1.668 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.148452e-02 | 1.668 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.148452e-02 | 1.668 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 2.148452e-02 | 1.668 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 1.922135e-02 | 1.716 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 1.630643e-02 | 1.788 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 2.123372e-02 | 1.673 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 2.123372e-02 | 1.673 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 2.123372e-02 | 1.673 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 1.970650e-02 | 1.705 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 1.970650e-02 | 1.705 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 1.970650e-02 | 1.705 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.119711e-02 | 1.674 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.160708e-02 | 1.665 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.851143e-02 | 1.733 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.977853e-02 | 1.704 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 1.681830e-02 | 1.774 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 2.001293e-02 | 1.699 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 1.988928e-02 | 1.701 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.741650e-02 | 1.759 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.924166e-02 | 1.716 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 1.659418e-02 | 1.780 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.856867e-02 | 1.731 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.681830e-02 | 1.774 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.121877e-02 | 1.673 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.630643e-02 | 1.788 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.630643e-02 | 1.788 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 2.121877e-02 | 1.673 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 2.123372e-02 | 1.673 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.659418e-02 | 1.780 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 2.160802e-02 | 1.665 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 2.174734e-02 | 1.663 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 2.175077e-02 | 1.663 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 2.211843e-02 | 1.655 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.322771e-02 | 1.634 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 2.364126e-02 | 1.626 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 2.364126e-02 | 1.626 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 2.364126e-02 | 1.626 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.389977e-02 | 1.622 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 2.467949e-02 | 1.608 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 2.524438e-02 | 1.598 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 2.530611e-02 | 1.597 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.538930e-02 | 1.595 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.538930e-02 | 1.595 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 2.565874e-02 | 1.591 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 2.689077e-02 | 1.570 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.689077e-02 | 1.570 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 2.689077e-02 | 1.570 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 2.725319e-02 | 1.565 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 2.739116e-02 | 1.562 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 2.754858e-02 | 1.560 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 2.782380e-02 | 1.556 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 2.791897e-02 | 1.554 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 2.791897e-02 | 1.554 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 2.791897e-02 | 1.554 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 2.791897e-02 | 1.554 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 2.849683e-02 | 1.545 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.849683e-02 | 1.545 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 2.849683e-02 | 1.545 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 2.866864e-02 | 1.543 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 2.943369e-02 | 1.531 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 2.968657e-02 | 1.527 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 2.982599e-02 | 1.525 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.991047e-02 | 1.524 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 3.051526e-02 | 1.515 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 3.065429e-02 | 1.514 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.214654e-02 | 1.493 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 3.214654e-02 | 1.493 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 3.218070e-02 | 1.492 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 3.284889e-02 | 1.483 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 3.289452e-02 | 1.483 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 3.361506e-02 | 1.473 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 3.400610e-02 | 1.468 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 3.404229e-02 | 1.468 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 3.404229e-02 | 1.468 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 3.404229e-02 | 1.468 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 3.406986e-02 | 1.468 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 3.459962e-02 | 1.461 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 3.528982e-02 | 1.452 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 3.528982e-02 | 1.452 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 3.528982e-02 | 1.452 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 3.543473e-02 | 1.451 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 3.615215e-02 | 1.442 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 3.615215e-02 | 1.442 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 3.615215e-02 | 1.442 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 3.615215e-02 | 1.442 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 3.615215e-02 | 1.442 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 3.615215e-02 | 1.442 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 3.644869e-02 | 1.438 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 3.775968e-02 | 1.423 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 3.840426e-02 | 1.416 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 3.877435e-02 | 1.411 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 3.877435e-02 | 1.411 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 4.342737e-02 | 1.362 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 4.362131e-02 | 1.360 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 4.363753e-02 | 1.360 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 4.363753e-02 | 1.360 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 4.375634e-02 | 1.359 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 4.375634e-02 | 1.359 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 4.375634e-02 | 1.359 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 4.471491e-02 | 1.350 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 4.471491e-02 | 1.350 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 4.471491e-02 | 1.350 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 4.471491e-02 | 1.350 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 4.495666e-02 | 1.347 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 4.495666e-02 | 1.347 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 4.581536e-02 | 1.339 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 4.641597e-02 | 1.333 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 4.641597e-02 | 1.333 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 4.649941e-02 | 1.333 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 4.649941e-02 | 1.333 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 4.694494e-02 | 1.328 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 4.703513e-02 | 1.328 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 4.703513e-02 | 1.328 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 4.703513e-02 | 1.328 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 4.703513e-02 | 1.328 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 4.703513e-02 | 1.328 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 4.782287e-02 | 1.320 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 4.782287e-02 | 1.320 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 7.438213e-02 | 1.129 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 7.438213e-02 | 1.129 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 7.438213e-02 | 1.129 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 7.438213e-02 | 1.129 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 7.438213e-02 | 1.129 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 7.438213e-02 | 1.129 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 7.438213e-02 | 1.129 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 7.438213e-02 | 1.129 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 6.162401e-02 | 1.210 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 5.953627e-02 | 1.225 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 5.486414e-02 | 1.261 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 6.408032e-02 | 1.193 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 7.415031e-02 | 1.130 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 7.070617e-02 | 1.151 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 6.653463e-02 | 1.177 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 5.548749e-02 | 1.256 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 6.924618e-02 | 1.160 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 5.217938e-02 | 1.283 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 5.946883e-02 | 1.226 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 5.439281e-02 | 1.264 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 7.322727e-02 | 1.135 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 7.322727e-02 | 1.135 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 7.322727e-02 | 1.135 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 5.903449e-02 | 1.229 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 5.965214e-02 | 1.224 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 7.322727e-02 | 1.135 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 6.110381e-02 | 1.214 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 6.110381e-02 | 1.214 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 6.404566e-02 | 1.194 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 5.402157e-02 | 1.267 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 5.778613e-02 | 1.238 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.946883e-02 | 1.226 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 5.778613e-02 | 1.238 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 7.388106e-02 | 1.131 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 5.431527e-02 | 1.265 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 6.696006e-02 | 1.174 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 6.696006e-02 | 1.174 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 5.486414e-02 | 1.261 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 6.408032e-02 | 1.193 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 5.903449e-02 | 1.229 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 7.415031e-02 | 1.130 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 6.476347e-02 | 1.189 | 1 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 5.984430e-02 | 1.223 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 6.162401e-02 | 1.210 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 5.333949e-02 | 1.273 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 6.976448e-02 | 1.156 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 5.402157e-02 | 1.267 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 7.232517e-02 | 1.141 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 5.347291e-02 | 1.272 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 6.408032e-02 | 1.193 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 7.362258e-02 | 1.133 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 5.333949e-02 | 1.273 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 7.109112e-02 | 1.148 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 5.254039e-02 | 1.280 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 7.047916e-02 | 1.152 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 7.047916e-02 | 1.152 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 6.400355e-02 | 1.194 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 7.466938e-02 | 1.127 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 7.485062e-02 | 1.126 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 7.586736e-02 | 1.120 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 7.685693e-02 | 1.114 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 7.685693e-02 | 1.114 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 7.794893e-02 | 1.108 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 7.820912e-02 | 1.107 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 8.007783e-02 | 1.096 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 8.007783e-02 | 1.096 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 8.105129e-02 | 1.091 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 8.105129e-02 | 1.091 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 8.105129e-02 | 1.091 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 8.276274e-02 | 1.082 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 8.336529e-02 | 1.079 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 8.495897e-02 | 1.071 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 8.506886e-02 | 1.070 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 8.506886e-02 | 1.070 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.506886e-02 | 1.070 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 8.506886e-02 | 1.070 | 0 | 0 |
| S Phase | R-HSA-69242 | 8.592917e-02 | 1.066 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 8.672662e-02 | 1.062 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 8.878410e-02 | 1.052 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 8.878410e-02 | 1.052 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 8.878410e-02 | 1.052 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 8.923548e-02 | 1.049 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 9.013330e-02 | 1.045 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 9.156506e-02 | 1.038 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 9.156506e-02 | 1.038 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 9.265768e-02 | 1.033 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.336717e-02 | 1.030 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 9.336717e-02 | 1.030 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 9.355210e-02 | 1.029 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 9.682341e-02 | 1.014 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 9.682341e-02 | 1.014 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 9.682341e-02 | 1.014 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 9.747167e-02 | 1.011 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.801937e-02 | 1.009 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 9.833935e-02 | 1.007 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 9.982896e-02 | 1.001 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 1.006803e-01 | 0.997 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 1.008649e-01 | 0.996 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 1.008649e-01 | 0.996 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 1.025053e-01 | 0.989 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.027588e-01 | 0.988 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 1.027588e-01 | 0.988 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.027588e-01 | 0.988 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 1.027588e-01 | 0.988 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.027635e-01 | 0.988 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.027635e-01 | 0.988 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.027635e-01 | 0.988 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 1.027635e-01 | 0.988 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 1.034140e-01 | 0.985 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 1.055959e-01 | 0.976 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.055959e-01 | 0.976 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.055959e-01 | 0.976 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.055959e-01 | 0.976 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 1.055959e-01 | 0.976 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.055959e-01 | 0.976 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.059818e-01 | 0.975 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.062948e-01 | 0.973 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.062948e-01 | 0.973 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.062948e-01 | 0.973 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.062948e-01 | 0.973 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.062948e-01 | 0.973 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.062948e-01 | 0.973 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.062948e-01 | 0.973 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 1.062948e-01 | 0.973 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 1.062948e-01 | 0.973 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 1.062948e-01 | 0.973 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 1.062948e-01 | 0.973 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 1.073800e-01 | 0.969 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 1.076174e-01 | 0.968 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 1.082433e-01 | 0.966 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.082433e-01 | 0.966 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 1.082433e-01 | 0.966 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 1.084795e-01 | 0.965 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 1.084795e-01 | 0.965 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 1.084795e-01 | 0.965 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.084795e-01 | 0.965 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.091007e-01 | 0.962 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 1.093945e-01 | 0.961 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 1.106184e-01 | 0.956 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 1.106184e-01 | 0.956 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 1.107119e-01 | 0.956 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 1.107119e-01 | 0.956 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.121991e-01 | 0.950 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.121991e-01 | 0.950 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.122603e-01 | 0.950 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 1.122603e-01 | 0.950 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 1.129125e-01 | 0.947 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 1.152392e-01 | 0.938 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.177624e-01 | 0.929 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 1.177624e-01 | 0.929 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.177624e-01 | 0.929 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.184736e-01 | 0.926 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.202463e-01 | 0.920 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.221877e-01 | 0.913 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 1.243032e-01 | 0.906 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.243032e-01 | 0.906 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 1.243032e-01 | 0.906 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.243032e-01 | 0.906 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 1.246009e-01 | 0.904 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 1.247029e-01 | 0.904 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.247029e-01 | 0.904 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 1.247029e-01 | 0.904 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 1.247029e-01 | 0.904 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 1.247029e-01 | 0.904 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 1.247029e-01 | 0.904 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 1.264800e-01 | 0.898 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 1.264800e-01 | 0.898 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 1.264800e-01 | 0.898 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 1.264800e-01 | 0.898 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.264800e-01 | 0.898 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 1.305025e-01 | 0.884 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 1.305419e-01 | 0.884 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.327500e-01 | 0.877 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.000468e-01 | 0.699 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 2.000468e-01 | 0.699 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.000468e-01 | 0.699 | 0 | 0 |
| RPIA deficiency: failed conversion of R5P to RU5P | R-HSA-5659996 | 2.000468e-01 | 0.699 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.000468e-01 | 0.699 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.000468e-01 | 0.699 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 2.000468e-01 | 0.699 | 0 | 0 |
| RPIA deficiency: failed conversion of RU5P to R5P | R-HSA-6791461 | 2.000468e-01 | 0.699 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 2.000468e-01 | 0.699 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 2.000468e-01 | 0.699 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.452763e-01 | 0.838 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.452763e-01 | 0.838 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 1.452763e-01 | 0.838 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 1.452763e-01 | 0.838 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.452763e-01 | 0.838 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 1.844347e-01 | 0.734 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.844347e-01 | 0.734 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.844347e-01 | 0.734 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.844347e-01 | 0.734 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 1.844347e-01 | 0.734 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 1.519336e-01 | 0.818 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 1.519336e-01 | 0.818 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.519336e-01 | 0.818 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 2.248572e-01 | 0.648 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.248572e-01 | 0.648 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 2.248572e-01 | 0.648 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 2.248572e-01 | 0.648 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 2.248572e-01 | 0.648 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 2.248572e-01 | 0.648 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 1.788345e-01 | 0.748 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 1.788345e-01 | 0.748 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 1.443482e-01 | 0.841 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.443482e-01 | 0.841 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.658407e-01 | 0.575 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 2.658407e-01 | 0.575 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 2.658407e-01 | 0.575 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 2.069021e-01 | 0.684 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 2.069021e-01 | 0.684 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 2.069021e-01 | 0.684 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 2.069021e-01 | 0.684 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 2.069021e-01 | 0.684 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.651093e-01 | 0.782 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.651093e-01 | 0.782 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 1.506012e-01 | 0.822 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 1.868577e-01 | 0.728 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.868577e-01 | 0.728 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 2.358665e-01 | 0.627 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 2.358665e-01 | 0.627 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 2.094609e-01 | 0.679 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.517194e-01 | 0.819 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 2.654723e-01 | 0.576 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.001430e-01 | 0.699 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 2.001430e-01 | 0.699 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 1.396321e-01 | 0.855 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 1.396321e-01 | 0.855 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 1.396321e-01 | 0.855 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 2.174204e-01 | 0.663 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 2.174204e-01 | 0.663 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 2.460567e-01 | 0.609 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 2.460567e-01 | 0.609 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 1.501092e-01 | 0.824 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 1.501092e-01 | 0.824 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 1.863094e-01 | 0.730 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 1.722079e-01 | 0.764 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.048394e-01 | 0.689 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 2.318750e-01 | 0.635 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 2.593924e-01 | 0.586 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 2.593924e-01 | 0.586 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 2.593924e-01 | 0.586 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 2.458588e-01 | 0.609 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 1.826043e-01 | 0.738 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 2.116352e-01 | 0.674 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 1.678131e-01 | 0.775 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 1.506012e-01 | 0.822 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 1.683135e-01 | 0.774 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 1.598793e-01 | 0.796 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 1.369730e-01 | 0.863 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.517194e-01 | 0.819 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 2.113807e-01 | 0.675 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 1.452763e-01 | 0.838 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 1.519336e-01 | 0.818 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.788345e-01 | 0.748 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 1.651093e-01 | 0.782 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 2.003193e-01 | 0.698 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 2.536472e-01 | 0.596 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 2.654723e-01 | 0.576 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 2.001430e-01 | 0.699 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.519336e-01 | 0.818 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 2.658407e-01 | 0.575 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 1.651093e-01 | 0.782 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 1.337285e-01 | 0.874 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 2.351782e-01 | 0.629 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.687798e-01 | 0.773 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 2.601206e-01 | 0.585 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.368769e-01 | 0.864 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 1.683135e-01 | 0.774 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 1.501092e-01 | 0.824 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 2.245845e-01 | 0.649 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 1.362288e-01 | 0.866 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 2.181940e-01 | 0.661 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 1.728671e-01 | 0.762 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.848026e-01 | 0.733 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 1.844347e-01 | 0.734 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 2.248572e-01 | 0.648 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 2.358665e-01 | 0.627 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 1.931449e-01 | 0.714 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 1.349114e-01 | 0.870 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 2.059631e-01 | 0.686 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 1.437148e-01 | 0.842 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 1.437148e-01 | 0.842 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.868577e-01 | 0.728 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 1.577291e-01 | 0.802 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 1.672422e-01 | 0.777 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 1.784854e-01 | 0.748 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 1.353307e-01 | 0.869 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 1.427450e-01 | 0.845 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 2.440905e-01 | 0.612 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 1.844347e-01 | 0.734 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 2.658407e-01 | 0.575 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 2.358665e-01 | 0.627 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 2.144543e-01 | 0.669 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 1.519336e-01 | 0.818 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 1.651093e-01 | 0.782 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 1.550397e-01 | 0.810 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 2.257446e-01 | 0.646 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.551218e-01 | 0.809 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 2.318750e-01 | 0.635 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 1.502455e-01 | 0.823 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 1.791993e-01 | 0.747 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 2.000468e-01 | 0.699 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.452763e-01 | 0.838 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.452763e-01 | 0.838 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 1.519336e-01 | 0.818 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 1.506012e-01 | 0.822 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 2.358665e-01 | 0.627 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 2.358665e-01 | 0.627 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 1.683135e-01 | 0.774 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 2.327852e-01 | 0.633 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 1.833997e-01 | 0.737 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 1.833997e-01 | 0.737 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 2.001430e-01 | 0.699 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.784854e-01 | 0.748 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 2.013562e-01 | 0.696 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 1.833997e-01 | 0.737 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 2.189266e-01 | 0.660 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 2.087676e-01 | 0.680 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 2.440905e-01 | 0.612 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 1.519336e-01 | 0.818 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 2.144543e-01 | 0.669 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 1.683135e-01 | 0.774 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 2.327852e-01 | 0.633 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 2.440905e-01 | 0.612 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.437148e-01 | 0.842 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 2.087676e-01 | 0.680 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 1.871397e-01 | 0.728 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 1.517194e-01 | 0.819 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 2.087676e-01 | 0.680 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 2.014946e-01 | 0.696 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 1.788345e-01 | 0.748 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 2.358665e-01 | 0.627 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 1.517194e-01 | 0.819 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 1.502455e-01 | 0.823 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 2.593924e-01 | 0.586 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.477832e-01 | 0.830 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 2.248572e-01 | 0.648 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 1.683135e-01 | 0.774 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 2.566976e-01 | 0.591 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 2.059631e-01 | 0.686 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 1.867930e-01 | 0.729 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 2.573746e-01 | 0.589 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 2.599772e-01 | 0.585 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 2.087676e-01 | 0.680 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 2.228364e-01 | 0.652 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.248572e-01 | 0.648 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 2.094609e-01 | 0.679 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.473698e-01 | 0.832 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.566976e-01 | 0.591 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 2.257446e-01 | 0.646 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 2.294905e-01 | 0.639 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 2.438691e-01 | 0.613 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.868577e-01 | 0.728 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 2.681489e-01 | 0.572 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 2.719136e-01 | 0.566 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 2.719136e-01 | 0.566 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 2.719136e-01 | 0.566 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 2.719136e-01 | 0.566 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 2.720839e-01 | 0.565 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.720839e-01 | 0.565 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 2.742662e-01 | 0.562 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 2.742662e-01 | 0.562 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 2.742662e-01 | 0.562 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 2.749748e-01 | 0.561 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 2.749748e-01 | 0.561 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 2.810677e-01 | 0.551 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 2.810677e-01 | 0.551 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 2.845285e-01 | 0.546 | 0 | 0 |
| Abasic sugar-phosphate removal via the single-nucleotide replacement pathway | R-HSA-73930 | 2.845285e-01 | 0.546 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 2.845285e-01 | 0.546 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 2.845285e-01 | 0.546 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.845285e-01 | 0.546 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.845285e-01 | 0.546 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.845285e-01 | 0.546 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.845285e-01 | 0.546 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 2.845285e-01 | 0.546 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 2.845285e-01 | 0.546 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 2.845285e-01 | 0.546 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.845285e-01 | 0.546 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 2.845285e-01 | 0.546 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.845285e-01 | 0.546 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 2.845285e-01 | 0.546 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.845285e-01 | 0.546 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 2.845285e-01 | 0.546 | 0 | 0 |
| Inhibition of Host mRNA Processing and RNA Silencing | R-HSA-168315 | 2.845285e-01 | 0.546 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.845285e-01 | 0.546 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.845285e-01 | 0.546 | 0 | 0 |
| Inhibition of membrane repair | R-HSA-9635644 | 2.845285e-01 | 0.546 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.845285e-01 | 0.546 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 2.885804e-01 | 0.540 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 2.907787e-01 | 0.536 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 2.908053e-01 | 0.536 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 2.908053e-01 | 0.536 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 2.913725e-01 | 0.536 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 2.914333e-01 | 0.535 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 2.914333e-01 | 0.535 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 2.925899e-01 | 0.534 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 2.954821e-01 | 0.529 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 2.954821e-01 | 0.529 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 2.954821e-01 | 0.529 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 2.983717e-01 | 0.525 | 1 | 1 |
| Cellular response to hypoxia | R-HSA-1234174 | 3.014497e-01 | 0.521 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 3.057695e-01 | 0.515 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 3.068164e-01 | 0.513 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 3.068164e-01 | 0.513 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 3.068164e-01 | 0.513 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 3.068164e-01 | 0.513 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 3.068164e-01 | 0.513 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 3.068164e-01 | 0.513 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 3.068164e-01 | 0.513 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 3.068164e-01 | 0.513 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 3.068513e-01 | 0.513 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 3.088340e-01 | 0.510 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 3.088340e-01 | 0.510 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 3.088340e-01 | 0.510 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 3.093619e-01 | 0.510 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 3.093619e-01 | 0.510 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 3.093619e-01 | 0.510 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 3.093619e-01 | 0.510 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 3.097487e-01 | 0.509 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 3.099005e-01 | 0.509 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 3.099005e-01 | 0.509 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 3.099005e-01 | 0.509 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 3.099005e-01 | 0.509 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 3.162301e-01 | 0.500 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 3.194359e-01 | 0.496 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 3.238941e-01 | 0.490 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 3.252977e-01 | 0.488 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 3.256781e-01 | 0.487 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 3.264264e-01 | 0.486 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 3.292233e-01 | 0.483 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 3.292233e-01 | 0.483 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 3.292233e-01 | 0.483 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.292233e-01 | 0.483 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 3.306823e-01 | 0.481 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 3.306823e-01 | 0.481 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 3.309869e-01 | 0.480 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 3.309869e-01 | 0.480 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 3.309869e-01 | 0.480 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 3.309869e-01 | 0.480 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 3.355594e-01 | 0.474 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 3.441690e-01 | 0.463 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 3.467435e-01 | 0.460 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 3.473292e-01 | 0.459 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 3.473292e-01 | 0.459 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 3.486924e-01 | 0.458 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 3.486924e-01 | 0.458 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 3.527451e-01 | 0.453 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 3.527451e-01 | 0.453 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 3.556922e-01 | 0.449 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 3.558631e-01 | 0.449 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 3.558631e-01 | 0.449 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 3.559544e-01 | 0.449 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.600927e-01 | 0.444 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 3.600927e-01 | 0.444 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.600927e-01 | 0.444 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 3.600927e-01 | 0.444 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 3.600927e-01 | 0.444 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.600927e-01 | 0.444 | 0 | 0 |
| Glycogen storage disease type IV (GBE1) | R-HSA-3878781 | 3.600927e-01 | 0.444 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.600927e-01 | 0.444 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 3.600927e-01 | 0.444 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 3.600927e-01 | 0.444 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.600927e-01 | 0.444 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.600927e-01 | 0.444 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 3.616349e-01 | 0.442 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 3.620209e-01 | 0.441 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 3.678978e-01 | 0.434 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 3.682546e-01 | 0.434 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 3.682546e-01 | 0.434 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 3.799420e-01 | 0.420 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 3.799420e-01 | 0.420 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 3.799420e-01 | 0.420 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.806922e-01 | 0.419 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 3.806922e-01 | 0.419 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 3.858608e-01 | 0.414 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 3.858608e-01 | 0.414 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 3.858608e-01 | 0.414 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 3.858608e-01 | 0.414 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 3.858608e-01 | 0.414 | 0 | 0 |
| Hypusine synthesis from eIF5A-lysine | R-HSA-204626 | 3.870200e-01 | 0.412 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 3.870200e-01 | 0.412 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 3.870200e-01 | 0.412 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 3.870200e-01 | 0.412 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 3.870200e-01 | 0.412 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 3.870200e-01 | 0.412 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.870200e-01 | 0.412 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 3.878583e-01 | 0.411 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 3.891707e-01 | 0.410 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 3.927690e-01 | 0.406 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 3.963736e-01 | 0.402 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 4.055831e-01 | 0.392 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 4.055831e-01 | 0.392 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.074539e-01 | 0.390 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 4.074539e-01 | 0.390 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 4.074539e-01 | 0.390 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 4.110550e-01 | 0.386 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 4.130965e-01 | 0.384 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 4.155155e-01 | 0.381 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 4.155155e-01 | 0.381 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 4.155155e-01 | 0.381 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 4.155155e-01 | 0.381 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 4.155155e-01 | 0.381 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 4.155155e-01 | 0.381 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 4.172151e-01 | 0.380 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 4.181089e-01 | 0.379 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 4.224799e-01 | 0.374 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 4.224799e-01 | 0.374 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.224799e-01 | 0.374 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 4.234718e-01 | 0.373 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 4.256107e-01 | 0.371 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 4.256107e-01 | 0.371 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 4.256107e-01 | 0.371 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 4.256107e-01 | 0.371 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 4.256107e-01 | 0.371 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 4.256107e-01 | 0.371 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 4.256107e-01 | 0.371 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 4.256107e-01 | 0.371 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 4.256107e-01 | 0.371 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 4.256107e-01 | 0.371 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.269940e-01 | 0.370 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.269940e-01 | 0.370 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 4.269940e-01 | 0.370 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.269940e-01 | 0.370 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 4.269940e-01 | 0.370 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 4.269940e-01 | 0.370 | 0 | 0 |
| Activated NTRK3 signals through PLCG1 | R-HSA-9034793 | 4.276801e-01 | 0.369 | 0 | 0 |
| PLC-gamma1 signalling | R-HSA-167021 | 4.276801e-01 | 0.369 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 4.276801e-01 | 0.369 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 4.276801e-01 | 0.369 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 4.276801e-01 | 0.369 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.276801e-01 | 0.369 | 0 | 0 |
| Defective HPRT1 disrupts guanine and hypoxanthine salvage | R-HSA-9734281 | 4.276801e-01 | 0.369 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.276801e-01 | 0.369 | 0 | 0 |
| Signalling to STAT3 | R-HSA-198745 | 4.276801e-01 | 0.369 | 0 | 0 |
| Inhibition of nitric oxide production | R-HSA-9636249 | 4.276801e-01 | 0.369 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 4.276801e-01 | 0.369 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 4.276801e-01 | 0.369 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 4.276801e-01 | 0.369 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 4.277293e-01 | 0.369 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 4.302738e-01 | 0.366 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 4.397085e-01 | 0.357 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 4.397085e-01 | 0.357 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 4.397085e-01 | 0.357 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 4.446916e-01 | 0.352 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 4.446916e-01 | 0.352 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 4.464337e-01 | 0.350 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 4.502750e-01 | 0.347 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 4.546814e-01 | 0.342 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 4.546814e-01 | 0.342 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 4.591860e-01 | 0.338 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 4.618590e-01 | 0.335 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 4.628912e-01 | 0.335 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 4.628912e-01 | 0.335 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 4.628912e-01 | 0.335 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 4.628912e-01 | 0.335 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 4.628912e-01 | 0.335 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 4.628912e-01 | 0.335 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 4.628912e-01 | 0.335 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 4.628912e-01 | 0.335 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 4.657304e-01 | 0.332 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 4.657304e-01 | 0.332 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 4.657304e-01 | 0.332 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 4.657304e-01 | 0.332 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 4.657304e-01 | 0.332 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 4.685916e-01 | 0.329 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 4.721070e-01 | 0.326 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 4.732724e-01 | 0.325 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 4.732724e-01 | 0.325 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 4.744585e-01 | 0.324 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 4.781838e-01 | 0.320 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 4.787313e-01 | 0.320 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 4.787313e-01 | 0.320 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 4.810564e-01 | 0.318 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 4.822757e-01 | 0.317 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 4.822757e-01 | 0.317 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 4.822757e-01 | 0.317 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 4.822757e-01 | 0.317 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 4.853217e-01 | 0.314 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 4.868360e-01 | 0.313 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 4.868360e-01 | 0.313 | 0 | 0 |
| Activated NTRK2 signals through PLCG1 | R-HSA-9026527 | 4.881325e-01 | 0.311 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 4.881325e-01 | 0.311 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 4.881325e-01 | 0.311 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 4.881325e-01 | 0.311 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 4.881325e-01 | 0.311 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 4.881325e-01 | 0.311 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 4.881325e-01 | 0.311 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.881325e-01 | 0.311 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 4.881325e-01 | 0.311 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 4.881325e-01 | 0.311 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 4.881325e-01 | 0.311 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 4.881325e-01 | 0.311 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 4.881325e-01 | 0.311 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 4.898058e-01 | 0.310 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 4.987077e-01 | 0.302 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 5.011594e-01 | 0.300 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 5.011594e-01 | 0.300 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 5.011594e-01 | 0.300 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 5.011594e-01 | 0.300 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 5.023569e-01 | 0.299 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 5.023569e-01 | 0.299 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 5.031423e-01 | 0.298 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 5.037389e-01 | 0.298 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 5.042304e-01 | 0.297 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 5.057036e-01 | 0.296 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 5.236711e-01 | 0.281 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 5.254997e-01 | 0.279 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 5.254997e-01 | 0.279 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 5.282707e-01 | 0.277 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 5.282707e-01 | 0.277 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 5.282707e-01 | 0.277 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 5.282707e-01 | 0.277 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 5.282707e-01 | 0.277 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 5.319497e-01 | 0.274 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 5.329536e-01 | 0.273 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 5.329536e-01 | 0.273 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 5.329536e-01 | 0.273 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 5.329536e-01 | 0.273 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 5.329536e-01 | 0.273 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 5.329536e-01 | 0.273 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 5.329536e-01 | 0.273 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 5.329536e-01 | 0.273 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 5.329536e-01 | 0.273 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 5.329536e-01 | 0.273 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 5.329536e-01 | 0.273 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 5.365534e-01 | 0.270 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 5.365534e-01 | 0.270 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 5.385498e-01 | 0.269 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 5.407347e-01 | 0.267 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 5.407347e-01 | 0.267 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 5.422026e-01 | 0.266 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 5.422026e-01 | 0.266 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 5.422026e-01 | 0.266 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 5.422026e-01 | 0.266 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 5.422026e-01 | 0.266 | 0 | 0 |
| PTK6 Activates STAT3 | R-HSA-8849474 | 5.422026e-01 | 0.266 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 5.422026e-01 | 0.266 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 5.422026e-01 | 0.266 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 5.422026e-01 | 0.266 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 5.422026e-01 | 0.266 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 5.432518e-01 | 0.265 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 5.481089e-01 | 0.261 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 5.481089e-01 | 0.261 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 5.545400e-01 | 0.256 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 5.587762e-01 | 0.253 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 5.587762e-01 | 0.253 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 5.635620e-01 | 0.249 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 5.635620e-01 | 0.249 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.644129e-01 | 0.248 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 5.655611e-01 | 0.248 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 5.655611e-01 | 0.248 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 5.655611e-01 | 0.248 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 5.655611e-01 | 0.248 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 5.677988e-01 | 0.246 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 5.701410e-01 | 0.244 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 5.701410e-01 | 0.244 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 5.787881e-01 | 0.237 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 5.797506e-01 | 0.237 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 5.821684e-01 | 0.235 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 5.821684e-01 | 0.235 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 5.821684e-01 | 0.235 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 5.828584e-01 | 0.234 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 5.828584e-01 | 0.234 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 5.828584e-01 | 0.234 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.905640e-01 | 0.229 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.905640e-01 | 0.229 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 5.905640e-01 | 0.229 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 5.905640e-01 | 0.229 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.905640e-01 | 0.229 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.905640e-01 | 0.229 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 5.905640e-01 | 0.229 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 5.905640e-01 | 0.229 | 0 | 0 |
| Loss-of-function mutations in DBT cause MSUD2 | R-HSA-9865113 | 5.905640e-01 | 0.229 | 0 | 0 |
| Loss-of-function mutations in DLD cause MSUD3/DLDD | R-HSA-9907570 | 5.905640e-01 | 0.229 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 5.905640e-01 | 0.229 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 5.905640e-01 | 0.229 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 5.905640e-01 | 0.229 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 5.905640e-01 | 0.229 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 5.905640e-01 | 0.229 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 5.905640e-01 | 0.229 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 5.905640e-01 | 0.229 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 5.905640e-01 | 0.229 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 5.915595e-01 | 0.228 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 5.964943e-01 | 0.224 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 5.964943e-01 | 0.224 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 5.964943e-01 | 0.224 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 5.964943e-01 | 0.224 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 5.964943e-01 | 0.224 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 5.964943e-01 | 0.224 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 6.004000e-01 | 0.222 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.021857e-01 | 0.220 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 6.043560e-01 | 0.219 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 6.043560e-01 | 0.219 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 6.043560e-01 | 0.219 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 6.043560e-01 | 0.219 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 6.068741e-01 | 0.217 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 6.107750e-01 | 0.214 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 6.124147e-01 | 0.213 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 6.190898e-01 | 0.208 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 6.205604e-01 | 0.207 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 6.257429e-01 | 0.204 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 6.257429e-01 | 0.204 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 6.257429e-01 | 0.204 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 6.257429e-01 | 0.204 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 6.257429e-01 | 0.204 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 6.257429e-01 | 0.204 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 6.257429e-01 | 0.204 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 6.278353e-01 | 0.202 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 6.278353e-01 | 0.202 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 6.324421e-01 | 0.199 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 6.338191e-01 | 0.198 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 6.338191e-01 | 0.198 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 6.338191e-01 | 0.198 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 6.338191e-01 | 0.198 | 0 | 0 |
| Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD | R-HSA-9865125 | 6.338191e-01 | 0.198 | 0 | 0 |
| Branched-chain ketoacid dehydrogenase kinase deficiency | R-HSA-9912481 | 6.338191e-01 | 0.198 | 0 | 0 |
| H139Hfs13* PPM1K causes a mild variant of MSUD | R-HSA-9912529 | 6.338191e-01 | 0.198 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 6.338191e-01 | 0.198 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 6.338191e-01 | 0.198 | 0 | 0 |
| Defective CHST3 causes SEDCJD | R-HSA-3595172 | 6.338191e-01 | 0.198 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 6.338191e-01 | 0.198 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 6.338191e-01 | 0.198 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 6.338191e-01 | 0.198 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 6.338191e-01 | 0.198 | 0 | 0 |
| Chylomicron clearance | R-HSA-8964026 | 6.338191e-01 | 0.198 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 6.378433e-01 | 0.195 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 6.419415e-01 | 0.193 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 6.471668e-01 | 0.189 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 6.491085e-01 | 0.188 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 6.518644e-01 | 0.186 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 6.518644e-01 | 0.186 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 6.518644e-01 | 0.186 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 6.518644e-01 | 0.186 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 6.533176e-01 | 0.185 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 6.533176e-01 | 0.185 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 6.533176e-01 | 0.185 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 6.533176e-01 | 0.185 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 6.533176e-01 | 0.185 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 6.533176e-01 | 0.185 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 6.533176e-01 | 0.185 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 6.635807e-01 | 0.178 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 6.653357e-01 | 0.177 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 6.704505e-01 | 0.174 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 6.705886e-01 | 0.174 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.705886e-01 | 0.174 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 6.718460e-01 | 0.173 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 6.718460e-01 | 0.173 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 6.718460e-01 | 0.173 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 6.725067e-01 | 0.172 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.725067e-01 | 0.172 | 0 | 0 |
| Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 | R-HSA-964827 | 6.725067e-01 | 0.172 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 6.725067e-01 | 0.172 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 6.725067e-01 | 0.172 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 6.725067e-01 | 0.172 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 6.725067e-01 | 0.172 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 6.725067e-01 | 0.172 | 0 | 0 |
| Defective CHSY1 causes TPBS | R-HSA-3595177 | 6.725067e-01 | 0.172 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 6.725067e-01 | 0.172 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.725067e-01 | 0.172 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 6.725067e-01 | 0.172 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 6.725067e-01 | 0.172 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.725067e-01 | 0.172 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 6.725067e-01 | 0.172 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 6.725067e-01 | 0.172 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 6.725067e-01 | 0.172 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 6.725067e-01 | 0.172 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 6.744610e-01 | 0.171 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 6.759136e-01 | 0.170 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 6.761089e-01 | 0.170 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 6.792457e-01 | 0.168 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 6.792457e-01 | 0.168 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 6.792457e-01 | 0.168 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 6.792457e-01 | 0.168 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 6.792457e-01 | 0.168 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 6.792457e-01 | 0.168 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 6.792457e-01 | 0.168 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 6.792457e-01 | 0.168 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 6.792457e-01 | 0.168 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 6.801955e-01 | 0.167 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 6.812621e-01 | 0.167 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 6.881105e-01 | 0.162 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 6.923677e-01 | 0.160 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 6.923677e-01 | 0.160 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 6.940779e-01 | 0.159 | 0 | 0 |
| Translation | R-HSA-72766 | 6.969880e-01 | 0.157 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 7.035672e-01 | 0.153 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 7.035672e-01 | 0.153 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 7.035672e-01 | 0.153 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 7.035672e-01 | 0.153 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 7.035672e-01 | 0.153 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 7.035672e-01 | 0.153 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 7.035672e-01 | 0.153 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 7.059145e-01 | 0.151 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 7.059145e-01 | 0.151 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 7.071090e-01 | 0.151 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 7.071090e-01 | 0.151 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 7.071090e-01 | 0.151 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.071090e-01 | 0.151 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 7.071090e-01 | 0.151 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 7.071090e-01 | 0.151 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 7.071090e-01 | 0.151 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 7.071090e-01 | 0.151 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 7.071090e-01 | 0.151 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 7.071090e-01 | 0.151 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 7.071090e-01 | 0.151 | 0 | 0 |
| Nucleotide salvage defects | R-HSA-9734207 | 7.071090e-01 | 0.151 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 7.071090e-01 | 0.151 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 7.071090e-01 | 0.151 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 7.071090e-01 | 0.151 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 7.071090e-01 | 0.151 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 7.119058e-01 | 0.148 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 7.119058e-01 | 0.148 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 7.119058e-01 | 0.148 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 7.146365e-01 | 0.146 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 7.175839e-01 | 0.144 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 7.263320e-01 | 0.139 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 7.263320e-01 | 0.139 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 7.263320e-01 | 0.139 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 7.263320e-01 | 0.139 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 7.263320e-01 | 0.139 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 7.302650e-01 | 0.137 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 7.304723e-01 | 0.136 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 7.380571e-01 | 0.132 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 7.380571e-01 | 0.132 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 7.380571e-01 | 0.132 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 7.380571e-01 | 0.132 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 7.380571e-01 | 0.132 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 7.380571e-01 | 0.132 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 7.380571e-01 | 0.132 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 7.380571e-01 | 0.132 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 7.380571e-01 | 0.132 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 7.380571e-01 | 0.132 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 7.384055e-01 | 0.132 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.440442e-01 | 0.128 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 7.475976e-01 | 0.126 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 7.475976e-01 | 0.126 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 7.475976e-01 | 0.126 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 7.475976e-01 | 0.126 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 7.475976e-01 | 0.126 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 7.475976e-01 | 0.126 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 7.475976e-01 | 0.126 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 7.475976e-01 | 0.126 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 7.480838e-01 | 0.126 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 7.531046e-01 | 0.123 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 7.531046e-01 | 0.123 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 7.536012e-01 | 0.123 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 7.565859e-01 | 0.121 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 7.647613e-01 | 0.116 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 7.657367e-01 | 0.116 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 7.657367e-01 | 0.116 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 7.657367e-01 | 0.116 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 7.657367e-01 | 0.116 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 7.674266e-01 | 0.115 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 7.674266e-01 | 0.115 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 7.674266e-01 | 0.115 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 7.674266e-01 | 0.115 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 7.681031e-01 | 0.115 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 7.681031e-01 | 0.115 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 7.681031e-01 | 0.115 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 7.686714e-01 | 0.114 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 7.686714e-01 | 0.114 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 7.686714e-01 | 0.114 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 7.686714e-01 | 0.114 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 7.686714e-01 | 0.114 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.813899e-01 | 0.107 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 7.858851e-01 | 0.105 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 7.858851e-01 | 0.105 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 7.858851e-01 | 0.105 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 7.858851e-01 | 0.105 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 7.872178e-01 | 0.104 | 0 | 0 |
| Conjugation of benzoate with glycine | R-HSA-177135 | 7.904928e-01 | 0.102 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.904928e-01 | 0.102 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.904928e-01 | 0.102 | 0 | 0 |
| Vitamin B1 (thiamin) metabolism | R-HSA-196819 | 7.904928e-01 | 0.102 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 7.904928e-01 | 0.102 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.904928e-01 | 0.102 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 7.914899e-01 | 0.102 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 7.954145e-01 | 0.099 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 7.954145e-01 | 0.099 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 8.010805e-01 | 0.096 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 8.010805e-01 | 0.096 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 8.030411e-01 | 0.095 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 8.030411e-01 | 0.095 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 8.030411e-01 | 0.095 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 8.092133e-01 | 0.092 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 8.094466e-01 | 0.092 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 8.094466e-01 | 0.092 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 8.125433e-01 | 0.090 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.126341e-01 | 0.090 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 8.126341e-01 | 0.090 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 8.126341e-01 | 0.090 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 8.126341e-01 | 0.090 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 8.126341e-01 | 0.090 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 8.126341e-01 | 0.090 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 8.126341e-01 | 0.090 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 8.126341e-01 | 0.090 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 8.126341e-01 | 0.090 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 8.126341e-01 | 0.090 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 8.189639e-01 | 0.087 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 8.189639e-01 | 0.087 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 8.189639e-01 | 0.087 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 8.226565e-01 | 0.085 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 8.226565e-01 | 0.085 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 8.226565e-01 | 0.085 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 8.226565e-01 | 0.085 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 8.238479e-01 | 0.084 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 8.299479e-01 | 0.081 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 8.324366e-01 | 0.080 | 0 | 0 |
| Maple Syrup Urine Disease | R-HSA-9865114 | 8.324366e-01 | 0.080 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 8.324366e-01 | 0.080 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 8.324366e-01 | 0.080 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 8.324366e-01 | 0.080 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 8.324366e-01 | 0.080 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.324366e-01 | 0.080 | 0 | 0 |
| Conjugation of salicylate with glycine | R-HSA-177128 | 8.324366e-01 | 0.080 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 8.324366e-01 | 0.080 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.324366e-01 | 0.080 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 8.324366e-01 | 0.080 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 8.324366e-01 | 0.080 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 8.337223e-01 | 0.079 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 8.337223e-01 | 0.079 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 8.337223e-01 | 0.079 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 8.337223e-01 | 0.079 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 8.337223e-01 | 0.079 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 8.365100e-01 | 0.078 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 8.376602e-01 | 0.077 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 8.417588e-01 | 0.075 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 8.430482e-01 | 0.074 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 8.467389e-01 | 0.072 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 8.473846e-01 | 0.072 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 8.473846e-01 | 0.072 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 8.473846e-01 | 0.072 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 8.473846e-01 | 0.072 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 8.496030e-01 | 0.071 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 8.501472e-01 | 0.071 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 8.501472e-01 | 0.071 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 8.501472e-01 | 0.071 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 8.501472e-01 | 0.071 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 8.501472e-01 | 0.071 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 8.501472e-01 | 0.071 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 8.585300e-01 | 0.066 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 8.600176e-01 | 0.065 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 8.600176e-01 | 0.065 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 8.600176e-01 | 0.065 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 8.600176e-01 | 0.065 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 8.600176e-01 | 0.065 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.600176e-01 | 0.065 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 8.657606e-01 | 0.063 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.659869e-01 | 0.062 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 8.659869e-01 | 0.062 | 0 | 0 |
| BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV | R-HSA-9859138 | 8.659869e-01 | 0.062 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 8.659869e-01 | 0.062 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.659869e-01 | 0.062 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 8.659869e-01 | 0.062 | 0 | 0 |
| N-glycan trimming and elongation in the cis-Golgi | R-HSA-964739 | 8.659869e-01 | 0.062 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 8.659869e-01 | 0.062 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.659869e-01 | 0.062 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.659869e-01 | 0.062 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 8.679263e-01 | 0.062 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 8.695970e-01 | 0.061 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 8.716861e-01 | 0.060 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 8.716861e-01 | 0.060 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.716861e-01 | 0.060 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 8.716861e-01 | 0.060 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 8.747828e-01 | 0.058 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.755937e-01 | 0.058 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 8.775179e-01 | 0.057 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 8.775179e-01 | 0.057 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 8.800333e-01 | 0.056 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 8.801531e-01 | 0.055 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.801531e-01 | 0.055 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.801531e-01 | 0.055 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 8.801531e-01 | 0.055 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 8.801531e-01 | 0.055 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 8.801531e-01 | 0.055 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 8.801531e-01 | 0.055 | 0 | 0 |
| Transport and metabolism of PAPS | R-HSA-174362 | 8.801531e-01 | 0.055 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 8.801531e-01 | 0.055 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 8.801531e-01 | 0.055 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.823811e-01 | 0.054 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 8.824529e-01 | 0.054 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 8.824529e-01 | 0.054 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.824529e-01 | 0.054 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 8.824529e-01 | 0.054 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.824529e-01 | 0.054 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 8.864856e-01 | 0.052 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.866781e-01 | 0.052 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 8.866781e-01 | 0.052 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 8.871836e-01 | 0.052 | 0 | 0 |
| Disease | R-HSA-1643685 | 8.922417e-01 | 0.050 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 8.923781e-01 | 0.049 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 8.925693e-01 | 0.049 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 8.925693e-01 | 0.049 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 8.925693e-01 | 0.049 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.928226e-01 | 0.049 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.928226e-01 | 0.049 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.928226e-01 | 0.049 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 8.928226e-01 | 0.049 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 8.928226e-01 | 0.049 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 8.928226e-01 | 0.049 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 8.928226e-01 | 0.049 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 8.928226e-01 | 0.049 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.928226e-01 | 0.049 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 8.948617e-01 | 0.048 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.015193e-01 | 0.045 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.026779e-01 | 0.044 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.026779e-01 | 0.044 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 9.041534e-01 | 0.044 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.041534e-01 | 0.044 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.041534e-01 | 0.044 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 9.041534e-01 | 0.044 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 9.041534e-01 | 0.044 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 9.041534e-01 | 0.044 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.041534e-01 | 0.044 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.080355e-01 | 0.042 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 9.099314e-01 | 0.041 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.099314e-01 | 0.041 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 9.099314e-01 | 0.041 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.099653e-01 | 0.041 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.113451e-01 | 0.040 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 9.142869e-01 | 0.039 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 9.142869e-01 | 0.039 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.142869e-01 | 0.039 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.142869e-01 | 0.039 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 9.142869e-01 | 0.039 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 9.142869e-01 | 0.039 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.157325e-01 | 0.038 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.167537e-01 | 0.038 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 9.176662e-01 | 0.037 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.176662e-01 | 0.037 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.201429e-01 | 0.036 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.202112e-01 | 0.036 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.230722e-01 | 0.035 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 9.233495e-01 | 0.035 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 9.233495e-01 | 0.035 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 9.233495e-01 | 0.035 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 9.233495e-01 | 0.035 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 9.233495e-01 | 0.035 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 9.233495e-01 | 0.035 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.233495e-01 | 0.035 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.235669e-01 | 0.035 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.247729e-01 | 0.034 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.252706e-01 | 0.034 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.289485e-01 | 0.032 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.289485e-01 | 0.032 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.289485e-01 | 0.032 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.314544e-01 | 0.031 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 9.314544e-01 | 0.031 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 9.314544e-01 | 0.031 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.314544e-01 | 0.031 | 0 | 0 |
| Amino Acid conjugation | R-HSA-156587 | 9.314544e-01 | 0.031 | 0 | 0 |
| Conjugation of carboxylic acids | R-HSA-159424 | 9.314544e-01 | 0.031 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.314544e-01 | 0.031 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 9.314544e-01 | 0.031 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.330353e-01 | 0.030 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.344095e-01 | 0.029 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.387028e-01 | 0.027 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 9.387028e-01 | 0.027 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.387028e-01 | 0.027 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 9.387028e-01 | 0.027 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.387028e-01 | 0.027 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.387028e-01 | 0.027 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.387028e-01 | 0.027 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.390676e-01 | 0.027 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.394809e-01 | 0.027 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.394809e-01 | 0.027 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.396473e-01 | 0.027 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 9.403135e-01 | 0.027 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.427738e-01 | 0.026 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.427738e-01 | 0.026 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.427738e-01 | 0.026 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.427738e-01 | 0.026 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.427738e-01 | 0.026 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.428681e-01 | 0.026 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.445597e-01 | 0.025 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 9.451850e-01 | 0.024 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 9.451850e-01 | 0.024 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 9.451850e-01 | 0.024 | 0 | 0 |
| Phenylalanine metabolism | R-HSA-8964208 | 9.451850e-01 | 0.024 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.478039e-01 | 0.023 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.478039e-01 | 0.023 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.478280e-01 | 0.023 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 9.485279e-01 | 0.023 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.487744e-01 | 0.023 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.487744e-01 | 0.023 | 0 | 0 |
| CS-GAG biosynthesis | R-HSA-2022870 | 9.509821e-01 | 0.022 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 9.509821e-01 | 0.022 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.509821e-01 | 0.022 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.509821e-01 | 0.022 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.522340e-01 | 0.021 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 9.522340e-01 | 0.021 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.524106e-01 | 0.021 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.524106e-01 | 0.021 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.524106e-01 | 0.021 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.527305e-01 | 0.021 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.561664e-01 | 0.019 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 9.561664e-01 | 0.019 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.561664e-01 | 0.019 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.561664e-01 | 0.019 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.561664e-01 | 0.019 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 9.563416e-01 | 0.019 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.566270e-01 | 0.019 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 9.589198e-01 | 0.018 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.604842e-01 | 0.018 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 9.608027e-01 | 0.017 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.608027e-01 | 0.017 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 9.608027e-01 | 0.017 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.608027e-01 | 0.017 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 9.610480e-01 | 0.017 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.618697e-01 | 0.017 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 9.619277e-01 | 0.017 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.624942e-01 | 0.017 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.640110e-01 | 0.016 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.649488e-01 | 0.015 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.649488e-01 | 0.015 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.649488e-01 | 0.015 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.651932e-01 | 0.015 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.659356e-01 | 0.015 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.675143e-01 | 0.014 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.683231e-01 | 0.014 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.686566e-01 | 0.014 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.686566e-01 | 0.014 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.686566e-01 | 0.014 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.686566e-01 | 0.014 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 9.686566e-01 | 0.014 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.686566e-01 | 0.014 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 9.686566e-01 | 0.014 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 9.686566e-01 | 0.014 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.712512e-01 | 0.013 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.713729e-01 | 0.013 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.719724e-01 | 0.012 | 0 | 0 |
| Diseases of branched-chain amino acid catabolism | R-HSA-9865118 | 9.719724e-01 | 0.012 | 0 | 0 |
| Linoleic acid (LA) metabolism | R-HSA-2046105 | 9.719724e-01 | 0.012 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.719724e-01 | 0.012 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 9.719724e-01 | 0.012 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.728665e-01 | 0.012 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 9.749375e-01 | 0.011 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.749375e-01 | 0.011 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.753199e-01 | 0.011 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.756272e-01 | 0.011 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 9.757414e-01 | 0.011 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.760791e-01 | 0.011 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.764078e-01 | 0.010 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.775892e-01 | 0.010 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.775892e-01 | 0.010 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.775892e-01 | 0.010 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.775892e-01 | 0.010 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.777282e-01 | 0.010 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.795594e-01 | 0.009 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.795741e-01 | 0.009 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.799604e-01 | 0.009 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.799604e-01 | 0.009 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.799604e-01 | 0.009 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 9.799604e-01 | 0.009 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.811352e-01 | 0.008 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.820138e-01 | 0.008 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.820809e-01 | 0.008 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.820809e-01 | 0.008 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.820809e-01 | 0.008 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.825831e-01 | 0.008 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.827999e-01 | 0.008 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.846992e-01 | 0.007 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.855888e-01 | 0.006 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.856727e-01 | 0.006 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.861054e-01 | 0.006 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.863209e-01 | 0.006 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 9.867553e-01 | 0.006 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.871890e-01 | 0.006 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.871890e-01 | 0.006 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.873855e-01 | 0.006 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.878160e-01 | 0.005 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.885385e-01 | 0.005 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 9.885449e-01 | 0.005 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.885449e-01 | 0.005 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 9.885449e-01 | 0.005 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.888898e-01 | 0.005 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.897573e-01 | 0.004 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.897573e-01 | 0.004 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.897573e-01 | 0.004 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.898287e-01 | 0.004 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.905087e-01 | 0.004 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.905707e-01 | 0.004 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.908415e-01 | 0.004 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.910887e-01 | 0.004 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.918110e-01 | 0.004 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.926779e-01 | 0.003 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.926779e-01 | 0.003 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.926779e-01 | 0.003 | 0 | 0 |
| Phenylalanine and tyrosine metabolism | R-HSA-8963691 | 9.926779e-01 | 0.003 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.926779e-01 | 0.003 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.928755e-01 | 0.003 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.934531e-01 | 0.003 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.942243e-01 | 0.003 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.942243e-01 | 0.003 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.947661e-01 | 0.002 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.947661e-01 | 0.002 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.949640e-01 | 0.002 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.950294e-01 | 0.002 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.951624e-01 | 0.002 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.952584e-01 | 0.002 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.953203e-01 | 0.002 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.957050e-01 | 0.002 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.957050e-01 | 0.002 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.958158e-01 | 0.002 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.958158e-01 | 0.002 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.958158e-01 | 0.002 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.961103e-01 | 0.002 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.962152e-01 | 0.002 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.962152e-01 | 0.002 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.962589e-01 | 0.002 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.962589e-01 | 0.002 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.962589e-01 | 0.002 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.963538e-01 | 0.002 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.966551e-01 | 0.001 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.966905e-01 | 0.001 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.970094e-01 | 0.001 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.970094e-01 | 0.001 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.970094e-01 | 0.001 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.970094e-01 | 0.001 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.971135e-01 | 0.001 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.973262e-01 | 0.001 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 9.973262e-01 | 0.001 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 9.973262e-01 | 0.001 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.976094e-01 | 0.001 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.978626e-01 | 0.001 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.980891e-01 | 0.001 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.981063e-01 | 0.001 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.984172e-01 | 0.001 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.984725e-01 | 0.001 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.985687e-01 | 0.001 | 0 | 0 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 9.986344e-01 | 0.001 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.986344e-01 | 0.001 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.986344e-01 | 0.001 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.986946e-01 | 0.001 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.990241e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.991276e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.992199e-01 | 0.000 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.992200e-01 | 0.000 | 0 | 0 |
| Digestion | R-HSA-8935690 | 9.992200e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.993750e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.994805e-01 | 0.000 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.995018e-01 | 0.000 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.995018e-01 | 0.000 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.995546e-01 | 0.000 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.995586e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.995988e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.996440e-01 | 0.000 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.996440e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.996676e-01 | 0.000 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.996792e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.996818e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.997454e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.997727e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.997968e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.998226e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.998376e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.998548e-01 | 0.000 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.998548e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.998548e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.998702e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.998893e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999012e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.999155e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.999155e-01 | 0.000 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.999184e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.999408e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999563e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999662e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999750e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999846e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999855e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999930e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999935e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999937e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999937e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999950e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999952e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999970e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999971e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999975e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999977e-01 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.999980e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999982e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999985e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999987e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999990e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.999990e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999993e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999994e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999994e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999995e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999997e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999997e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999998e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 9.999998e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999999e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999999e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
