NIM1

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
Log-Odds: S Sites / S Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0AVT1 S732 Sugiyama UBA6 MOP4 UBE1L2 NHKALQLLHCFPLDIRLKDGsLFWQsPKRPPsPIKFDLNEP
A0MZ66 S473 Sugiyama SHTN1 KIAA1598 LGtLNKSTSSRsLKsLDPENsEtELERILRRRKVtAEADss
A4FU28 S140 Sugiyama CTAGE9 AAAEEARSLEATCEKLSRsNsELEDEILCLEKDLKEEKSKH
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 S939 Sugiyama POTEF A26C1B VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A6NIH7 S229 Sugiyama UNC119B QLSEDVIRLMIENPYETRSDsFYFVDNKLIMHNKADYAYNG
A6NKT7 S1006 Sugiyama RGPD3 RGP3 FGKKDLNFKGFSGAGEKLFSsQYGKMANKANtsGDFEKDDD
A8MPP1 S279 Sugiyama DDX11L8 LVSLGSRQNLCVNEDVRSLGsVQLINDRCVDMQRSRHEKKK
O00180 S326 Sugiyama KCNK1 HOHO1 KCNO1 TWIK1 DQAAGMKEDQKQNEPFVATQsSACVDGPANH__________
O00193 S24 Sugiyama SMAP C11orf58 ARESHPHGVKRsAsPDDDLGssNWEAADLGNEERKQKFLRL
O00231 S298 Sugiyama PSMD11 RYAGRQTEALKCVAQASKNRsLADFEKALTDYRAELRDDPI
O00232 S343 Sugiyama PSMD12 DYGMELRKGsLEsPAtDVFGsTEEGEKRWKDLKNRVVEHNI
O00273 S302 Sugiyama DFFA DFF1 DFF45 H13 TETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDLQN
O00273 S37 Sugiyama DFFA DFF1 DFF45 H13 TLKPCLLRRNysREQHGVAAsCLEDLRSKACDILAIDKSLT
O00299 S121 Sugiyama CLIC1 G6 NCC27 PESNTAGLDIFAKFSAYIKNsNPALNDNLEKGLLKALKVLD
O00468 S641 Sugiyama AGRN AGRIN PRCEHPPPGPVCGSDGVTyGsACELREAACLQQtQIEEARA
O00571 S82 Sugiyama DDX3X DBX DDX3 ssKDKDAyssFGsRsDsRGKssFFsDRGsGsRGRFDDRGRs
O14639 S452 Sugiyama ABLIM1 ABLIM KIAA0059 LIMAB1 PtPsAEGyQDVRDRMIHRstsQGsINsPVySRHsYtPTTSR
O14974 S299 Sugiyama PPP1R12A MBS MYPT1 YLEELQKKQNLLHsEKRDKKsPLIEstANMDNNQSQKTFKN
O14974 S910 Sugiyama PPP1R12A MBS MYPT1 yETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDST
O14980 S1055 Sugiyama XPO1 CRM1 LEEREIALRQADEEKHKRQMsVPGIFNPHEIPEEMCD____
O14980 S690 Sugiyama XPO1 CRM1 QQATKNVDILKDPETVKQLGsILKTNVRACKAVGHPFVIQL
O15013 S1284 Sugiyama ARHGEF10 KIAA0294 AAIWLGDSLGSMTQKsDLssssGsLsLsHGsssLEHRSEDs
O15226 S618 Sugiyama NKRF ITBA4 NRF VNKIAKRDIEQIIRNYARsEsHtDLtFsRELTNDERKQIHQ
O15355 S349 Sugiyama PPM1G PPM1C tTAVVALIRGKQLIVANAGDsRCVVsEAGKALDMsyDHKPE
O15427 S436 Sugiyama SLC16A3 MCT3 MCT4 EPQPEVAAAEEEKLHKPPADsGVDLREVEHFLKAEPEKNGE
O43143 S656 Sugiyama DHX15 DBP1 DDX15 QNHESVQWCYDNFINYRSLMsADNVRQQLSRIMDRFNLPRR
O43175 S280 Sugiyama PHGDH PGDH3 DVFTEEPPRDRALVDHENVIsCPHLGAsTKEAQSRCGEEIA
O43290 S437 Sugiyama SART1 VVRADDLLPLGDQtQDGDFGsRLRGRGRRRVsEVEEEKEPV
O43488 S40 Sugiyama AKR7A2 AFAR AFAR1 AKR7 SPPPEARALAMSRPPPPRVAsVLGTMEMGRRMDAPAsAAAV
O43707 S507 Sugiyama ACTN4 DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID
O43707 S511 Sugiyama ACTN4 VNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAIDQLHL
O43707 S763 Sugiyama ACTN4 IARTINEVENQILtRDAKGIsQEQMQEFRASFNHFDKDHGG
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43707 T509 Sugiyama ACTN4 HNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAIDQL
O43765 S197 Sugiyama SGTA SGT SGT1 EAVAYYKKALELDPDNEtyKsNLKIAELKLREAPSPTGGVG
O43823 S323 Sugiyama AKAP8 AKAP95 RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE
O60271 S194 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 LERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPAGDG
O60271 S710 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 AVGVNLSGGKTRDGGsVVGAsVFYKDVAGLDTEGSKQRsAs
O60291 S515 Sugiyama MGRN1 KIAA0544 RNF156 sFItEEVDESssPQQGTRAAsIENVLQDssPEHCGRGPPAD
O60341 S126 Sugiyama KDM1A AOF2 KDM1 KIAA0601 LSD1 EGRRTsRRKRAKVEyREMDEsLANLsEDEyysEEERNAKAE
O60506 S587 Sugiyama SYNCRIP HNRPQ NSAP1 ADGYNQPDSKRRQTNNQNWGsQPIAQQPLQGGDHSGNYGYK
O60664 S179 Sugiyama PLIN3 M6PRBP1 TIP47 QSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGKsEEW
O60664 S93 Sugiyama PLIN3 M6PRBP1 TIP47 AAVsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQP
O60716 S230 Sugiyama CTNND1 KIAA0384 PDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRA
O60716 S252 Sugiyama CTNND1 KIAA0384 sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL
O60749 S119 Sugiyama SNX2 TRG9 AVtPVtPttLIAPRIESKsMsAPVIFDRsREEIEEEANGDI
O60749 S365 Sugiyama SNX2 TRG9 AKSAAMLGNsEDHTALSRALsQLAEVEEKIDQLHQEQAFAD
O60763 S751 Sugiyama USO1 VDP EIGRLREEIEELKRNQELLQsQLTEKDSMIENMKSSQtSGT
O60907 S569 Sugiyama TBL1X TBL1 IFEVCWNARGDKVGASASDGsVCVLDLRK____________
O75083 S11 Sugiyama WDR1 __________MPYEIKKVFAsLPQVERGVSKIIGGDPKGNN
O75128 S324 Sugiyama COBL KIAA0633 PPPGSGPPVQDKAsEKVsLGsQIDLQKKKRRAPAPPPPQPP
O75179 S243 Sugiyama ANKRD17 GTAR KIAA0697 RAEStANAGQSDNRSLAEACsEGDVNAVRKLLIEGRSVNEH
O75369 S2107 Sugiyama FLNB FLN1L FLN3 TABP TAP VKISGEGRVKEsITRTSRAPsVAtVGsICDLNLKIPEINss
O75369 S2113 Sugiyama FLNB FLN1L FLN3 TABP TAP GRVKEsITRTSRAPsVAtVGsICDLNLKIPEINssDMSAHV
O75489 S110 Sugiyama NDUFS3 PDGVIPVLTFLRDHTNAQFKsLVDLTAVDVPTRQNRFEIVY
O75534 S584 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR YSLSKGKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRP
O75534 S766 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR AAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDNsMGFG
O75643 S17 Sugiyama SNRNP200 ASCC3L1 BRR2 HELIC2 KIAA0788 ____MADVTARsLQYEYKANsNLVLQADRsLIDRTRRDEPT
O75688 S186 Sugiyama PPM1B PP2CB TQDHKPCNPREKERIQNAGGsVMIQRVNGsLAVSRALGDYD
O75821 S189 Sugiyama EIF3G EIF3S4 CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK
O75822 S127 Sugiyama EIF3J EIF3S1 PRO0391 VLtPEEQLADKLRLKKLQEEsDLELAKEtFGVNNAVyGIDA
O75822 S202 Sugiyama EIF3J EIF3S1 PRO0391 VLVRDVCISLEIDDLKKITNsLTVLCsEKQKQEKQSKAKKK
O75828 S69 Sugiyama CBR3 SDR21C2 QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLNVLVN
O75874 S9 Sugiyama IDH1 PICD ____________MSKKIsGGsVVEMQGDEMTRIIWELIKEK
O94874 S778 Sugiyama UFL1 KIAA0776 MAXER NLBP RCAD DKEQEDVASTTRKELQELSssIKDLVLKSRKSsVTEE____
O95155 S118 Sugiyama UBE4B HDNB1 KIAA0684 UFD2 QsLsRsQsMDIDGVSCEKsMsQVDVDsGIENMEVDENDRRE
O95155 S97 Sugiyama UBE4B HDNB1 KIAA0684 UFD2 QssEGVssLsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsM
O95218 S181 Sugiyama ZRANB2 ZIS ZNF265 DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR
O95347 S315 Sugiyama SMC2 CAPE SMC2L1 PRO0324 ILRSLEDALAEAQRVNTKSQsAFDLKKKNLACEESKRKELE
O95453 S342 Sugiyama PARN DAN LLDTKLMASTQPFKDIINNTsLAELEKRLKETPFNPPKVES
O95757 S586 Sugiyama HSPA4L APG1 HSPH3 OSP94 DRLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGK
O95757 S599 Sugiyama HSPA4L APG1 HSPH3 OSP94 sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND
O95819 S800 Sugiyama MAP4K4 HGK KIAA0687 NIK DVEQEGADESTSGPEDTRAAsSLNLSNGETESVKTMIVHDD
P00338 S105 Sugiyama LDHA PIG19 VTANsKLVIItAGARQQEGEsRLNLVQRNVNIFKFIIPNVV
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00558 S115 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 FLKDCVGPEVEKACANPAAGsVILLENLRFHVEEEGKGKDA
P00558 S174 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL
P00558 S175 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN
P00568 S38 Sugiyama AK1 GSGKGTQCEKIVQKyGytHLstGDLLRSEVSSGSARGKKLs
P01023 S593 Sugiyama A2M CPAMD5 FWP007 SPSQSLPASHAHLRVTAAPQsVCALRAVDQSVLLMKPDAEL
P04040 S515 Sugiyama CAT ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________
P04040 S517 Sugiyama CAT LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S356 Sugiyama ALDOA ALDA sLACQGKytPsGQAGAAAsEsLFVsNHAy____________
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04792 S187 Sugiyama HSPB1 HSP27 HSP28 APMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAAK__
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05023 S520 Sugiyama ATP1A1 EPQHLLVMKGAPERILDRCssILLHGKEQPLDEELKDAFQN
P05362 S43 Sugiyama ICAM1 GPGNAQTSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETP
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05783 S312 Sugiyama KRT18 CYK18 PIG46 AETTLTELRRtVQsLEIDLDsMRNLKAsLENsLREVEARYA
P05783 S93 Sugiyama KRT18 CYK18 PIG46 GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR
P05787 S291 Sugiyama KRT8 CYK8 ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P06733 S27 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06744 T109 Sugiyama GPI KINyTEGRAVLHVALRNRsNtPILVDGKDVMPEVNKVLDKM
P07195 S106 Sugiyama LDHB VtANSKIVVVtAGVRQQEGEsRLNLVQRNVNVFKFIIPQIV
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 S320 Sugiyama LDHB GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______
P07195 S44 Sugiyama LDHB ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07237 S439 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB NIVIAKMDstANEVEAVKVHsFPtLKFFPAsADRtVIDyNG
P07339 S37 Sugiyama CTSD CPSD PASALVRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQ
P07339 S42 Sugiyama CTSD CPSD VRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQAVPAV
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07437 S40 Sugiyama TUBB TUBB5 OK/SW-cl.56 FWEVISDEHGIDPTGtyHGDsDLQLDRIsVyyNEAtGGKyV
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07602 S29 Sugiyama PSAP GLBA SAP1 SLLGAALAGPVLGLKECtRGsAVWCQNVKTASDCGAVKHCL
P07711 S329 Sugiyama CTSL CTSL1 GGyVKMAKDRRNHCGIAsAAsyPtV________________
P07737 S30 Sugiyama PFN1 NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S164 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGT
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S169 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA TVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILH
P07900 S399 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S52 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P07942 T415 Sugiyama LAMB1 CERCTCDPAGSQNEGICDSYtDFSTGLIAGQCRCKLNVEGE
P08174 S78 Sugiyama CD55 CR DAF DtVItyKCEEsFVKIPGEKDsVICLKGSQWSDIEEFCNRSC
P08195 S286 Sugiyama SLC3A2 MDU1 KNQKDDVAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVIL
P08195 S402 Sugiyama SLC3A2 MDU1 SSDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQY
P08195 S518 Sugiyama SLC3A2 MDU1 DIPGAVSANMTVKGQsEDPGsLLsLFRRLsDQRsKERSLLH
P08238 S159 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGT
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S164 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILH
P08238 S391 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK
P08238 S452 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AFSKNLKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEy
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S470 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 S482 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S532 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yMtEPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T94 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSGtKAFM
P08559 S331 Sugiyama PDHA1 PHE1A RsKsDPIMLLKDRMVNSNLAsVEELKEIDVEVRKEIEDAAQ
P09211 S66 Sugiyama GSTP1 FAEES3 GST3 ASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQE
P09651 S368 Sugiyama HNRNPA1 HNRPA1 FAKPRNQGGyGGssssssyGsGRRF________________
P09661 S226 Sugiyama SNRPA1 NAIANAstLAEVERLKGLLQsGQIPGRERRsGPtDDGEEEM
P09923 S189 Sugiyama ALPI RVQHAsPAGtyAHtVNRNWysDADMPASARQEGCQDIATQL
P09972 S17 Sugiyama ALDOC ALDC ____MPHSYPALSAEQKKELsDIALRIVAPGKGILAADEsV
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG41 S140 Sugiyama CTAGE8 AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH
P0CG47 S57 Sugiyama UBB PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0CG48 S57 Sugiyama UBC PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7 S54 Sugiyama TUBA3C TUBA2 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P10398 S157 Sugiyama ARAF ARAF1 PKS PKS2 SSKVPTVCVDMSTNRQQFyHsVQDLsGGsRQHEAPsNRPLN
P10412 S58 Sugiyama H1-4 H1F4 HIST1H1E PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P10768 S189 Sugiyama ESD VSAFAPICNPVLCPWGKKAFsGyLGTDQsKWKAyDAtHLVK
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S40 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P11279 S141 Sugiyama LAMP1 NLSDTHLFPNASSKEIKtVEsITDIRADIDKKYRCVSGTQV
P11413 S117 Sugiyama G6PD KLEDFFARNsyVAGQyDDAAsyQRLNsHMNALHLGsQANRL
P11532 S3624 Sugiyama DMD AKVNGttVssPstsLQRsDssQPMLLRVVGSQTSDSMGEED
P11586 S765 Sugiyama MTHFD1 MTHFC MTHFD ARMFGIPVVVAVNAFKTDTEsELDLIsRLSREHGAFDAVKC
P12004 S172 Sugiyama PCNA sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE
P12268 S416 Sugiyama IMPDH2 IMPD2 APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12277 S129 Sugiyama CKB CKBB DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG
P12814 S744 Sugiyama ACTN1 IARTINEVENQILtRDAKGIsQEQMNEFRAsFNHFDRDHsG
P12956 S560 Sugiyama XRCC6 G22P1 VtKRKHDNEGSGSKRPKVEysEEELKTHISKGTLGKFTVPM
P12956 Y559 Sugiyama XRCC6 G22P1 KVtKRKHDNEGSGSKRPKVEysEEELKTHISKGTLGKFTVP
P13010 S318 Sugiyama XRCC5 G22P2 NDDDETEVLKEDIIQGFRyGsDIVPFSKVDEEQMKYKSEGK
P13489 S178 Sugiyama RNH1 PRI RNH SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13489 S225 Sugiyama RNH1 PRI RNH KLEsCGVTSDNCRDLCGIVAsKASLRELALGSNKLGDVGMA
P13489 S50 Sugiyama RNH1 PRI RNH CQVVRLDDCGLTEARCKDISsALRVNPALAELNLRSNELGD
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13667 S470 Sugiyama PDIA4 ERP70 ERP72 FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP
P13674 S383 Sugiyama P4HA1 P4HA AtIsNPITGDLETVHYRISKsAWLsGyENPVVsRINMRIQD
P13674 S395 Sugiyama P4HA1 P4HA TVHYRISKsAWLsGyENPVVsRINMRIQDLTGLDVSTAEEL
P13797 S339 Sugiyama PLS3 PRIDINMsGFNETDDLKRAEsMLQQADKLGCRQFVTPADVV
P13798 S187 Sugiyama APEH D3F15S2 D3S48E DNF15S2 EKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQFV
P13798 S27 Sugiyama APEH D3F15S2 D3S48E DNF15S2 LsEPEEAAALyRGLSRQPALsAACLGPEVtTQyGGQyRTVH
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 S222 Sugiyama PKM OIP3 PK2 PK3 PKM2 sLGsKKGVNLPGAAVDLPAVsEKDIQDLKFGVEQDVDMVFA
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S172 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 VGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSELI
P14625 S447 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 PKyLNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRK
P14625 S514 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK
P14625 S515 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ
P14625 S64 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14625 S650 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 KIEKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtG
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P14625 Y652 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 EKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtGKD
P14866 S544 Sugiyama HNRNPL HNRPL P/OKcl.14 LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH
P15311 S535 Sugiyama EZR VIL2 EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P15924 S2526 Sugiyama DSP ITITGSDGSTRVVLVDRKtGsQyDIQDAIDKGLVDRKFFDQ
P16152 S69 Sugiyama CBR1 CBR CRN SDR21C1 QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLDVLVN
P16402 S59 Sugiyama H1-3 H1F3 HIST1H1D PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P16403 S58 Sugiyama H1-2 H1F2 HIST1H1C PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P17066 S42 Sugiyama HSPA6 HSP70B' VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P17174 S82 Sugiyama GOT1 ANDNsLNHEyLPILGLAEFRsCAsRLALGDDsPALKEKRVG
P17544 S44 Sugiyama ATF7 ATFA LAVHKHKHEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEV
P17706 S72 Sugiyama PTPN2 PTPT SPYDHSRVKLQNAENDyINAsLVDIEEAQRSYILTQGPLPN
P17987 S374 Sugiyama TCP1 CCT1 CCTA ERICDDELILIKNTKARTsAsIILRGANDFMCDEMERSLHD
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18206 S809 Sugiyama VCL ELsKtIsPMVMDAKAVAGNIsDPGLQKsFLDsGyRILGAVA
P18615 S139 Sugiyama NELFE RD RDBP DLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEGPGAG
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18827 S243 Sugiyama SDC1 SDC VAVEPDRRNQsPVDQGAtGAsQGLLDRKEVLGGVIAGGLVG
P19338 S328 Sugiyama NCL NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK
P19338 S356 Sugiyama NCL LAVVDVRIGMTRKFGyVDFEsAEDLEKALELtGLKVFGNEI
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P20042 S67 Sugiyama EIF2S2 EIF2B EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P21333 S2152 Sugiyama FLNA FLN FLN1 VKVTGEGRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQ
P21333 S2158 Sugiyama FLNA FLN FLN1 GRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQDMtAQV
P22059 S802 Sugiyama OSBP OSBP1 ELTHIyRGEyWECKEKQDWSsCPDIF_______________
P22061 S119 Sugiyama PCMT1 MVGCTGKVIGIDHIKELVDDsVNNVRKDDPTLLssGRVQLV
P22314 S46 Sugiyama UBA1 A1S9T UBE1 AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA
P22314 S460 Sugiyama UBA1 A1S9T UBE1 TEDKCLQRQNRyDGQVAVFGsDLQEKLGKQKYFLVGAGAIG
P22626 S189 Sugiyama HNRNPA2B1 HNRPA2B1 IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF
P23284 S150 Sugiyama PPIB CYPB LKHyGPGWVsMANAGKDTNGsQFFITTVKTAWLDGKHVVFG
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23526 T185 Sugiyama AHCY SAHH yKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGIKR
P23588 S122 Sugiyama EIF4B NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P23919 S195 Sugiyama DTYMK CDC8 TMPK TYMK WKMVDASKSIEAVHEDIRVLsEDAIRTATEKPLGELWK___
P24534 S140 Sugiyama EEF1B2 EEF1B EF1B EERLAQYESKKAKKPALVAKssILLDVKPWDDEtDMAKLEE
P24539 S142 Sugiyama ATP5PB ATP5F1 DFADKLNEQKLAQLEEAKQAsIQHIQNAIDTEKsQQALVQK
P25054 S1389 Sugiyama APC DP2.5 PKsPPEHYVQETPLMFsRCTsVSsLDSFESRSIASSVQSEP
P25116 Y420 Sugiyama F2R CF2R PAR1 TR sGQLMAsKMDTCsSNLNNsIyKKLLT_______________
P25398 S107 Sugiyama RPS12 EWVGLCKIDREGKPRKVVGCsCVVVKDYGKESQAKDVIEEy
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T107 Sugiyama RPL13 BBC1 OK/SW-cl.46 HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF
P27348 S145 Sugiyama YWHAQ YFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHP
P27348 S63 Sugiyama YWHAQ LLsVAyKNVVGGRRSAWRVIsSIEQKTDTSDKKLQLIKDYR
P27708 S1859 Sugiyama CAD RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27816 S827 Sugiyama MAP4 VAKtttAAAVAstGPssRsPstLLPKKPTAIKTEGKPAEVK
P27824 S362 Sugiyama CANX WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK
P28838 S194 Sugiyama LAP3 LAPEP PEPS SAKLyGsGDQEAWQKGVLFAsGQNLARQLMETPANEMTPtR
P29144 S176 Sugiyama TPP2 FDVANNGSsQANKLIKEELQsQVELLNsFEKKYSDPGPVYD
P29401 S443 Sugiyama TKT EDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAAN
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 S64 Sugiyama EEF1D EF1D sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI
P30038 S513 Sugiyama ALDH4A1 ALDH4 P5CDH ATKVLRNAAGNFYINDKStGsIVGQQPFGGARASGTNDKPG
P30038 T511 Sugiyama ALDH4A1 ALDH4 P5CDH QEATKVLRNAAGNFYINDKStGsIVGQQPFGGARASGTNDK
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30050 S26 Sugiyama RPL12 DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI
P30622 S195 Sugiyama CLIP1 CYLN1 RSN AAKEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIG
P30622 S197 Sugiyama CLIP1 CYLN1 RSN KEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIGDR
P30876 S467 Sugiyama POLR2B SLATGNWGDQKKAHQARAGVsQVLNRLTFASTLSHLRRLNs
P31150 S316 Sugiyama GDI1 GDIL OPHN2 RABGDIA XAP4 QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM
P31327 S597 Sugiyama CPS1 ADTIGyPVMIRSAyALGGLGsGICPNRETLMDLSTKAFAMT
P31327 S898 Sugiyama CPS1 LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31327 Y590 Sugiyama CPS1 IEDALKAADTIGyPVMIRSAyALGGLGsGICPNRETLMDLS
P31939 S202 Sugiyama ATIC PURH OK/SW-cl.86 tAQyDEAISDyFRKQYSKGVsQMPLRyGMNPHQtPAQLytL
P31946 S65 Sugiyama YWHAB LLsVAyKNVVGARRSsWRVIsSIEQKTERNEKKQQMGKEYR
P34897 S81 Sugiyama SHMT2 QREKDRQCRGLELIAsENFCsRAALEALGsCLNNKYSEGYP
P34897 S90 Sugiyama SHMT2 GLELIAsENFCsRAALEALGsCLNNKYSEGYPGKRyyGGAE
P34931 S42 Sugiyama HSPA1L VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P34932 S414 Sugiyama HSPA4 APG2 HSPH2 ITDVVPYPISLRWNsPAEEGssDCEVFSKNHAAPFSKVLTF
P35237 S306 Sugiyama SERPINB6 PI6 PTI LRNLGMTDAFELGKADFSGMsQTDLSLSKVVHKSFVEVNEE
P35579 S1892 Sugiyama MYH9 LKQLKRQLEEAEEEAQRANAsRRKLQRELEDAtEtADAMNR
P35606 S160 Sugiyama COPB2 GHTHYVMQIVINPKDNNQFAsAsLDRtIKVWQLGsssPNFT
P35606 S350 Sugiyama COPB2 MGDAEIKDGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVC
P35813 S181 Sugiyama PPM1A PPPM1A TQDHKPSNPLEKERIQNAGGsVMIQRVNGsLAVSRALGDFD
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 S185 Sugiyama TAGLN2 KIAA0120 CDABP0035 NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______
P37802 S83 Sugiyama TAGLN2 KIAA0120 CDABP0035 CELINALYPEGQAPVKKIQAstMAFKQMEQIsQFLQAAERY
P38606 S384 Sugiyama ATP6V1A ATP6A1 ATP6V1A1 VPP2 RLAEMPADSGYPAyLGARLAsFYERAGRVKCLGNPEREGSV
P38646 S212 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646 S549 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P40763 S181 Sugiyama STAT3 APRF KMKVVENLQDDFDFNyKTLKsQGDMQDLNGNNQsVTRQKMQ
P40818 S719 Sugiyama USP8 KIAA0055 UBPY KPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtPT
P41252 S827 Sugiyama IARS1 IARS PRVREELIDKKTESAVSQMQsVIELGRVIRDRKTIPIKYPL
P42025 S247 Sugiyama ACTR1B CTRN2 NPQKDEALETEKVQYTLPDGsTLDVGPARFRAPELLFQPDL
P42224 S132 Sugiyama STAT1 ERKILENAQRFNQAQSGNIQsTVMLDKQKELDSKVRNVKDK
P42566 S655 Sugiyama EPS15 AF1P PFGKIDPFGGDPFKGSDPFAsDCFFRQSTDPFAtsstDPFs
P43034 S152 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM
P43246 S540 Sugiyama MSH2 GYYFRVTCKEEKVLRNNKNFsTVDIQKNGVKFTNSKLtsLN
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P43490 S472 Sugiyama NAMPT PBEF PBEF1 EYGQDLLHTVFKNGKVTKsysFDEIRKNAQLNIELEAAHH_
P46013 S1098 Sugiyama MKI67 PAARVTGMKKWPRtPKEEAQsLEDLAGFKELFQtPGPsEEs
P46459 S298 Sugiyama NSF NAREPKVVNGPEILNKyVGEsEANIRKLFADAEEEQRRLGA
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46940 S1448 Sugiyama IQGAP1 KIAA0051 AIRDAKTPDKMKKsKsVKEDsNLtLQEKKEKIQTGLKKLTE
P46940 S482 Sugiyama IQGAP1 KIAA0051 LINRALESGDVNTVWKQLsssVtGLTNIEEENCQRYLDELM
P47712 S729 Sugiyama PLA2G4A CPLA2 PLA2G4 KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA
P47712 S731 Sugiyama PLA2G4A CPLA2 PLA2G4 AMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA__
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P48643 S270 Sugiyama CCT5 CCTE KIAA0098 ILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQ
P48643 S51 Sugiyama CCT5 CCTE KIAA0098 LEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtVT
P48741 S42 Sugiyama HSPA7 HSP70B VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA
P49321 S659 Sugiyama NASP IEELKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsst
P49321 S662 Sugiyama NASP LKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsstsGF
P49327 S265 Sugiyama FASN FAS TILNAGTNTDGFKEQGVtFPsGDIQEQLIRSLyQsAGVAPE
P49327 T2215 Sugiyama FASN FAS DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49368 S212 Sugiyama CCT3 CCTG TRIC5 EIDIKKYARVEKIPGGIIEDsCVLRGVMINKDVTHPRMRRY
P49368 S458 Sugiyama CCT3 CCTG TRIC5 RAVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtW
P49588 S627 Sugiyama AARS1 AARS ATHILNFALRSVLGEADQKGsLVAPDRLRFDFTAKGAMSTQ
P49736 S170 Sugiyama MCM2 BM28 CCNL1 CDCL1 KIAA0030 KRRQVERAtEDGEEDEEMIEsIENLEDLKGHSVREWVsMAG
P49748 S489 Sugiyama ACADVL VLCAD RLFVALQGCMDKGKELSGLGsALKNPFGNAGLLLGEAGKQL
P49792 S1981 Sugiyama RANBP2 NUP358 FGKKDPNFKGFSGAGEKLFSsQYGKMANKANtsGDFEKDDD
P50395 S316 Sugiyama GDI2 RABGDIB QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM
P50395 S396 Sugiyama GDI2 RABGDIB IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD
P50395 S427 Sugiyama GDI2 RABGDIB ttHFEttCDDIKNIYKRMtGsEFDFEEMKRKKNDIYGED__
P50416 S612 Sugiyama CPT1A CPT1 SMTRLFREGRTETVRSCTTEsCDFVRAMVDPAQTVEQRLKL
P50990 S150 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EGYEIACRKAHEILPNLVCCsAKNLRDIDEVssLLRTSIMS
P50990 S373 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 SEVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVD
P50990 S380 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 VVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDDGVNtFK
P50990 T381 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 VVFKHEKEDGAIstIVLRGstDNLMDDIERAVDDGVNtFKV
P50991 S51 Sugiyama CCT4 CCTD SRB AQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtIt
P50991 T201 Sugiyama CCT4 CCTD SRB SLLsPMSVNAVMKVIDPAtAtsVDLRDIKIVKKLGGTIDDC
P51532 S1380 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 EEEEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEI
P51532 S1382 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P52298 S13 Sugiyama NCBP2 CBP20 PIG55 ________MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQE
P52569 S464 Sugiyama SLC7A2 ATRC2 CAT2 KCsPEKDGLGssPRVTSKsEsQVTMLQRQGFSMRTLFCPSL
P52597 S63 Sugiyama HNRNPF HNRPF VHFIYTREGRQsGEAFVELGsEDDVKMALKKDRESMGHRyI
P52788 S57 Sugiyama SMS ESVHTWQDHGYLATYTNKNGsFANLRIYPHGLVLLDLQSYD
P53396 S455 Sugiyama ACLY ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP
P53621 S389 Sugiyama COPA SYNPAENAVLLCTRAsNLENstyDLytIPKDADsQNPDAPE
P54105 S195 Sugiyama CLNS1A CLCI ICLN SHLTAEGQATLERLEGMLsQsVssQYNMAGVRtEDsIRDyE
P54105 S198 Sugiyama CLNS1A CLCI ICLN TAEGQATLERLEGMLsQsVssQYNMAGVRtEDsIRDyEDGM
P54252 S260 Sugiyama ATXN3 ATX3 MJD MJD1 SCA3 IDMEDEEADLRRAIQLsMQGssRNIsQDMtQtsGTNLTSEE
P54652 S41 Sugiyama HSPA2 VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA
P55010 S10 Sugiyama EIF5 ___________MSVNVNRsVsDQFyRyKMPRLIAKVEGKGN
P55036 S266 Sugiyama PSMD4 MCB1 AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ
P55036 S358 Sugiyama PSMD4 MCB1 VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_
P55060 S342 Sugiyama CSE1L CAS XPO2 ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF
P55060 S366 Sugiyama CSE1L CAS XPO2 KVIVPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAA
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55072 S37 Sugiyama VCP HEL-220 HEL-S-70 LKQKNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTV
P55072 S765 Sugiyama VCP HEL-220 HEL-S-70 RsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGAGPsQ
P55854 S27 Sugiyama SUMO3 SMT3A SMT3H1 KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60228 S442 Sugiyama EIF3E EIF3S6 INT6 IEKKLNQNSRSEAPNWAtQDsGFy_________________
P60228 Y445 Sugiyama EIF3E EIF3S6 INT6 KLNQNSRSEAPNWAtQDsGFy____________________
P60520 S39 Sugiyama GABARAPL2 FLC3A GEF2 AKIRAKYPDRVPVIVEKVSGsQIVDIDKRKYLVPSDITVAQ
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S239 Sugiyama ACTB VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P61081 S175 Sugiyama UBE2M UBC12 NNRRLFEQNVQRSMRGGyIGstyFERCLK____________
P61163 T248 Sugiyama ACTR1A CTRN1 PQKDETLETEKAQyyLPDGstIEIGPSRFRAPELLFRPDLI
P61221 S186 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 AIIKPQYVDQIPKAAKGtVGsILDRKDETKTQAIVCQQLDL
P61326 S106 Sugiyama MAGOH MAGOHA QELEIVIGDEHISFTTSKIGsLIDVNQSKDPEGLRVFYYLV
P61916 S29 Sugiyama NPC2 HE1 LLLALSTAAQAEPVQFKDCGsVDGVIKEVNVsPCPtQPCQL
P61956 S28 Sugiyama SUMO2 SMT3B SMT3H2 EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S64 Sugiyama YWHAG LLsVAyKNVVGARRSsWRVIsSIEQKtsADGNEKKIEMVRA
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S156 Sugiyama YWHAE AtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLGLALN
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62736 S241 Sugiyama ACTA2 ACTSA ACTVS GIG46 VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62906 S64 Sugiyama RPL10A NEDD6 QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH
P62979 S57 Sugiyama RPS27A UBA80 UBCEP1 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA
P62987 S57 Sugiyama UBA52 UBCEP2 PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI
P63104 T30 Sugiyama YWHAZ AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S239 Sugiyama ACTG1 ACTG VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63267 S240 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P68032 S241 Sugiyama ACTC1 ACTC VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 S241 Sugiyama ACTA1 ACTA VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 S54 Sugiyama TUBA1B GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
P78344 S36 Sugiyama EIF4G2 DAP5 OK/SW-cl.75 ssGGGGsRGAPQHYPKTAGNsEFLGKTPGQNAQKWIPARST
P78347 S547 Sugiyama GTF2I BAP135 WBSCR6 IIQVGNRIKFVIKRPELLTHsttEVTQPRtNtPVKEDWNVR
P78527 S2955 Sugiyama PRKDC HYRC HYRC1 EYDVLRGIFTSEIGTKQITQsALLAEARSDYSEAAKQYDEA
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S86 Sugiyama RPL24 EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE
P83731 T83 Sugiyama RPL24 QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
Q00613 S375 Sugiyama HSF1 HSTF1 TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL
Q01082 S1388 Sugiyama SPTBN1 SPTB2 TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy
Q01082 S2048 Sugiyama SPTBN1 SPTB2 VAEAWLLGQEPyLssREIGQsVDEVEKLIKRHEAFEKSAAT
Q01082 S2184 Sugiyama SPTBN1 SPTB2 ssPIPsPtsDRKAKTALPAQsAAtLPARtQEtPsAQMEGFL
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q01581 S324 Sugiyama HMGCS1 HMGCS VKLEDTYFDRDVEKAFMKASsELFSQKTKASLLVSNQNGNM
Q01581 S404 Sugiyama HMGCS1 HMGCS YSLKVTQDATPGSALDKITAsLCDLKSRLDSRTGVAPDVFA
Q01970 S1041 Sugiyama PLCB3 TKEGEDEAKRYQEFQNRQVQsLLELREAQVDAEAQRRLEHL
Q02818 S224 Sugiyama NUCB1 NUC RKLEEQQRRHREHPKVNVPGsQAQLKEVWEELDGLDPNRFN
Q04637 S1238 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI RDAVKREAALPPVsPLKAALsEEELEKKsKAIIEEyLHLND
Q04726 S622 Sugiyama TLE3 KIAA1547 VWDLHNQTLVRQFQGHTDGAsCIDISHDGTKLWTGGLDNTV
Q04917 S64 Sugiyama YWHAH YWHA1 LLsVAyKNVVGARRSsWRVIsSIEQKTMADGNEKKLEKVKA
Q06210 S261 Sugiyama GFPT1 GFAT GFPT GsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDA
Q06323 S31 Sugiyama PSME1 IFI5111 QAKVDVFREDLCTKtENLLGsyFPKKIsELDAFLKEPALNE
Q06323 S55 Sugiyama PSME1 IFI5111 KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE
Q07021 S164 Sugiyama C1QBP GC1QBP HABP1 SF2P32 DGEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVL
Q07021 S213 Sugiyama C1QBP GC1QBP HABP1 SF2P32 VGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDSLDW
Q07021 T214 Sugiyama C1QBP GC1QBP HABP1 SF2P32 GQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDSLDWA
Q07960 S47 Sugiyama ARHGAP1 CDC42GAP RHOGAP1 SIDEKNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDI
Q08209 S492 Sugiyama PPP3CA CALNA CNA EAKGLDRINERMPPRRDAMPsDANLNsINKALTSETNGTDS
Q08378 S1127 Sugiyama GOLGA3 NKKLALELEHEKGKLTGLGQsNAALREHNSILETALAKREA
Q08378 S501 Sugiyama GOLGA3 ERAMTDLQNMLEAKNAsLAssNNDLQVAEEQyQRLMAKVED
Q08379 S123 Sugiyama GOLGA2 SQNHDADNVPNLMDETKTFSsTESLRQLSQQLNGLVCESAT
Q09028 S146 Sugiyama RBBP4 RBAP48 EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE
Q09666 S220 Sugiyama AHNAK PM227 QsGKtVIRLPsGsGAAsPtGsAVDIRAGAIsAsGPELQGAG
Q12906 S46 Sugiyama ILF3 DRBF MPHOSPH4 NF90 EELEAVQNMVsHtERALKAVsDWIDEQEKGssEQAEsDNMD
Q12931 S361 Sugiyama TRAP1 HSP75 HSPC5 SIFYVPDMKPSMFDVSRELGsSVALYSRKVLIQTKATDILP
Q13011 S240 Sugiyama ECH1 SLVNELAFTARKMMADEALGsGLVSRVFPDKEVMLDAALAL
Q13098 S474 Sugiyama GPS1 COPS1 CSN1 MLRAAVLRNQIHVKsPPREGsQGELtPANsQsRMstNM___
Q13136 S338 Sugiyama PPFIA1 LIP1 MEERITTLEKRYLAAQREATsVHDLNDKLENEIANKDSMHR
Q13136 S668 Sugiyama PPFIA1 LIP1 EEKENTEQRAEEIESRVGsGsLDNLGRFRSMssIPPYPAss
Q13155 S48 Sugiyama AIMP2 JTV1 PRO0992 PNVHGRSyGPAPGAGHVQEEsNLsLQALESRQDDILKRLYE
Q13200 S147 Sugiyama PSMD2 TRAP2 SVLAMTMSGERECLKYRLVGsQEELASWGHEYVRHLAGEVA
Q13243 S153 Sugiyama SRSF5 HRS SFRS5 SRP40 EVTFADAHRPKLNEGVVEFAsYGDLKNAIEKLSGKEINGRK
Q13263 S479 Sugiyama TRIM28 KAP1 RNF96 TIF1B ssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERLDLDLtA
Q13263 S784 Sugiyama TRIM28 KAP1 RNF96 TIF1B DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK
Q13283 S67 Sugiyama G3BP1 G3BP sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN
Q13347 S217 Sugiyama EIF3I EIF3S2 TRIP1 sRDMtMFVtASKDNTAKLFDsttLEHQKTFRTERPVNSAAL
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13596 S368 Sugiyama SNX1 AKSLAMLGSSEDNTALSRALsQLAEVEEKIEQLHQEQANND
Q13625 S714 Sugiyama TP53BP2 ASPP2 BBP PRPLsPtKLLPFLSNPYRNQsDADLEALRKKLSNAPRPLKK
Q13765 S186 Sugiyama NACA HSD48 sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q14008 S1873 Sugiyama CKAP5 KIAA0097 LyEyKKKYsDADIEPFLKNSsQFFQSYVERGLRVIEMEREG
Q14126 S553 Sugiyama DSG2 CDHF5 VIDKPPGMAEKWKIARQEstsVLLQQSEKKLGRSEIQFLIS
Q14141 S411 Sugiyama SEPTIN6 KIAA0128 SEP2 SEPT6 DEVNAFKQRKTAAELLQsQGsQAGGsQtLKRDKEKKNNPWL
Q14141 T418 Sugiyama SEPTIN6 KIAA0128 SEP2 SEPT6 QRKTAAELLQsQGsQAGGsQtLKRDKEKKNNPWLCTE____
Q14152 S215 Sugiyama EIF3A EIF3S10 KIAA0139 RKLCDNLRMHLsQIQRHHNQstAINLNNPESQsMHLETRLV
Q14152 S492 Sugiyama EIF3A EIF3S10 KIAA0139 VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ
Q14152 S495 Sugiyama EIF3A EIF3S10 KIAA0139 ARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQsMP
Q14157 S356 Sugiyama UBAP2L KIAA0144 NICE4 HsMVsMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLA
Q14157 S360 Sugiyama UBAP2L KIAA0144 NICE4 sMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLAAQHS
Q14203 S31 Sugiyama DCTN1 RTPSGSRMsAEASARPLRVGsRVEVIGKGHRGTVAYVGATL
Q14203 S967 Sugiyama DCTN1 DRETVIKELKKSLKIKGEELsEANVRLSLLEKKLDSAAKDA
Q14204 S3920 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 tyDAEFQHFLRGNEIVLsAGsTPRIQGLTVEQAEAVVRLSC
Q14432 S273 Sugiyama PDE3A RYVEQILPQSAEAAPREHLGsQLIAGTKEDIPVFKRRRRss
Q14498 S336 Sugiyama RBM39 HCC1 RNPC2 LAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGR
Q14568 S164 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGT
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 S169 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 TVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILH
Q14568 S52 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q14677 S163 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 DRLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSK
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14980 S1181 Sugiyama NUMA1 NMP22 NUMA DsALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQD
Q15005 S33 Sugiyama SPCS2 KIAA0102 SPC25 GsGGCsGAGGAsNCGtGSGRsGLLDKWKIDDKPVKIDKWDG
Q15084 S428 Sugiyama PDIA6 ERP5 P5 TXNDC7 EREPWDGRDGELPVEDDIDLsDVELDDLGKDEL________
Q15172 S472 Sugiyama PPP2R5A EELWKKLEELKLKKALEKQNsAyNMHSILSNTSAE______
Q15172 S49 Sugiyama PPP2R5A VRKAQRQKRsQGssQFRsQGsQAELHPLPQLKDATSNEQQE
Q15181 S127 Sugiyama PPA1 IOPPP PP NDKHTGCCGDNDPIDVCEIGsKVCARGEIIGVKVLGILAMI
Q15185 S85 Sugiyama PTGES3 P23 TEBP KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN
Q15334 S1041 Sugiyama LLGL1 DLG4 HUGL HUGL1 TTLDTTGDVTVEDVKDFLGssEEsEKNLRNLAEDEAHACAI
Q15642 S296 Sugiyama TRIP10 CIP4 STOT STP FARPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRS
Q15751 S1514 Sugiyama HERC1 AESRLVHtsPNYRLIKsRsEsDLsQPEsDEEGYALsGRRNV
Q15751 S2436 Sugiyama HERC1 KKHRHEsEEKGDVEQKPESEsALDMRTGLTSDDVKSQSTTS
Q15818 S91 Sugiyama NPTX1 TILSQKETIRELTAKLGRCEsQsTLDPGAGEARAGGGRKQP
Q15818 S93 Sugiyama NPTX1 LSQKETIRELTAKLGRCEsQsTLDPGAGEARAGGGRKQPGS
Q16204 S325 Sugiyama CCDC6 D10S170 TST1 QRKLQREMERREALCRQLsEsEssLEMDDERYFNEMsAQGL
Q16513 S582 Sugiyama PKN2 PRK2 PRKCL2 tVTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQD
Q16513 S583 Sugiyama PKN2 PRK2 PRKCL2 VTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQDs
Q16513 S590 Sugiyama PKN2 PRK2 PRKCL2 LEPEPPPAPPRAssLGEIDEssELRVLDIPGQDsEtVFDIQ
Q16543 S339 Sugiyama CDC37 CDC37A DAISKMDPTDAKYHMQRCIDsGLWVPNSKASEAKEGEEAGP
Q16576 S145 Sugiyama RBBP7 RBAP46 EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE
Q16630 S165 Sugiyama CPSF6 CFIM68 PKRELHGQNPVVtPCNKQFLsQFEMQSRKTTQSGQMSGEGK
Q16719 S443 Sugiyama KYNU VVCDKRNPNGIRVAPVPLyNsFHDVyKFTNLLtsILDsAET
Q4V328 S291 Sugiyama GRIPAP1 KIAA1167 HKAQLARTQKLQQELEAANQsLAELRDQRQGERLEHAAALR
Q53EL6 S46 Sugiyama PDCD4 H731 GDEENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKN
Q562R1 S240 Sugiyama ACTBL2 VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S405 Sugiyama HSP90AB3P HSP90BC YMTEPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK
Q58FF8 S305 Sugiyama HSP90AB2P HSP90BB RVVYMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKR
Q5JTH9 S515 Sugiyama RRP12 KIAA0690 CVFFEACGRQAHPVMRKCLQsLCDLRLSPHFPHTAALDQAV
Q5JVF3 S24 Sugiyama PCID2 HT004 ITINQYLQQVYEAIDSRDGAsCAELVSFKHPHVANPRLQMA
Q5T035 S66 Sugiyama FAM120A2P C9orf129 LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERSLPI
Q5T4S7 S1723 Sugiyama UBR4 KIAA0462 KIAA1307 RBAF600 EISYAKYGSFFCDCGAKEDGsCLALVKRTPssGMsSTMKES
Q5VT52 S1070 Sugiyama RPRD2 KIAA0460 HSPC099 TATDQQQQEEHYRIETRVsssCLDLPDSTEEKGAPIETLGy
Q6EEV6 S28 Sugiyama SUMO4 SMT3H4 EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC
Q6EMK4 S487 Sugiyama VASN SLITL2 UNQ314/PRO357/PRO1282 GIEPVSPTSLRVGLQRYLQGssVQLRSLRLTYRNLSGPDKR
Q6EMK4 S488 Sugiyama VASN SLITL2 UNQ314/PRO357/PRO1282 IEPVSPTSLRVGLQRYLQGssVQLRSLRLTYRNLSGPDKRL
Q6FI81 S170 Sugiyama CIAPIN1 CUA001 PRO0915 ESDNLLFVQITGKKPNFEVGsSRQLKLsITKKssPsVKPAV
Q6GYQ0 T798 Sugiyama RALGAPA1 GARNL1 KIAA0884 TULIP1 tGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDMS
Q6NVY1 S381 Sugiyama HIBCH PADLKEVtEEDLNNHFKSLGsSDLKF_______________
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2 S54 Sugiyama TUBA3E GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q6PID6 S19 Sugiyama TTC33 __MASFGWKRKIGEKVSKVTsQQFEAEAADEKDVVDNDEGN
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 S939 Sugiyama POTEE A26C1A POTE2 VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6UVK1 S321 Sugiyama CSPG4 MCSP DQYPTHTSNRGVLSYLEPRGsLLLGGLDAEASRHLQEHRLG
Q6UX04 S203 Sugiyama CWC27 SDCCAG10 UNQ438/PRO871 KKEKPEEEVKKLKPKGTKNFsLLsFGEEAEEEEEEVNRVSQ
Q6VN20 S69 Sugiyama RANBP10 KIAA1464 QETPLPRSWSPKDKYNYIGLsQGNLRVHYKGHGKNHKDAAS
Q6XQN6 S102 Sugiyama NAPRT FHIP NAPRT1 SVLPPDTDPAFFEHLRALDCsEVTVRALPEGSLAFPGVPLL
Q6YHU6 S1024 Sugiyama THADA GITA KIAA1767 FNQAKILKEHDsFDMKDLNAsVVNIDtstEIKGKEVKTCDV
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 S54 Sugiyama TUBA1A TUBA3 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q7L2H7 S367 Sugiyama EIF3M HFLB5 PCID1 GA17 PNAS-125 WQQLyDTLNAWKQNLNKVKNsLLsLsDt_____________
Q7Z2W4 S492 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 VQATGRIADDADPRVALVNDsLsDVtsTtssRVDDHDSEEI
Q7Z417 S655 Sugiyama NUFIP2 KIAA1321 PIG1 LGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsIWNL
Q7Z417 S671 Sugiyama NUFIP2 KIAA1321 PIG1 DsWGsFDLRAAIVYHTKEMEsIWNLQKQDPKRIItyNEAMD
Q7Z460 S545 Sugiyama CLASP1 KIAA0622 MAST1 yHTLESSyQKALQSHLKNSDsIVsLPQsDRsssssQEsLNR
Q7Z6Z7 T3321 Sugiyama HUWE1 KIAA0312 KIAA1578 UREB1 HSPC272 FQIQRSGGRKHTEKHAsGGstVHIHPQAAPVVCRHVLDTLI
Q86UF2 S140 Sugiyama CTAGE6 CTAGE6P AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH
Q86V81 S239 Sugiyama ALYREF ALY BEF THOC4 tRGGARGRGRGAGRNSKQQLsAEELDAQLDAyNARMDts__
Q86VQ1 S226 Sugiyama GLCCI1 sCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQRSKQ
Q8IUD2 S824 Sugiyama ERC1 ELKS KIAA1081 RAB6IP2 KKKsAQMLEEARRREDNLNDsSQQLQDSLRKKDDRIEELEE
Q8IV48 S57 Sugiyama ERI1 3'EXO THEX1 EtQQCKFDGQETKGSKFITssAsDFsDPVyKEIAITNGCIN
Q8IWW6 S656 Sugiyama ARHGAP12 RRPTLQAVREKGYIKDQVFGsNLANLCQRENGTVPKFVKLC
Q8IWZ3 S1429 Sugiyama ANKHD1 KIAA1085 MASK VBARP PP2500 CVETIVKAKDQQAAEANKNAsILLKELDLEKSREESRKQAL
Q8IX94 S140 Sugiyama CTAGE4 AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH
Q8IY84 S119 Sugiyama NIM1K NIM1 KVAIKILDKTKLDQKTQRLLsREISsMEKLHHPNIIRLYEV
Q8IY84 S124 Sugiyama NIM1K NIM1 ILDKTKLDQKTQRLLsREISsMEKLHHPNIIRLYEVVETLS
Q8IY84 S206 Sugiyama NIM1K NIM1 HMHENQIIHRDLKAENVFyTsNtCVKVGDFGFSTVSKKGEM
Q8IY84 S24 Sugiyama NIM1K NIM1 VYMNGGGLVNPHYARWDRRDsVESGCQTESSKEGEEGQPRQ
Q8IY84 S381 Sugiyama NIM1K NIM1 LEHLGITEEHIRNNQGRDARssITGVYRIILHRVQRKKALE
Q8IY84 S382 Sugiyama NIM1K NIM1 EHLGITEEHIRNNQGRDARssITGVYRIILHRVQRKKALES
Q8IY84 S82 Sugiyama NIM1K NIM1 VREITLGKRIGFYRIRGEIGsGNFsQVKLGIHSLTKEKVAI
Q8IY84 S86 Sugiyama NIM1K NIM1 TLGKRIGFYRIRGEIGsGNFsQVKLGIHSLTKEKVAIKILD
Q8IY84 T208 Sugiyama NIM1K NIM1 HENQIIHRDLKAENVFyTsNtCVKVGDFGFSTVSKKGEMLN
Q8IY84 T229 GPS6|EPSD NIM1K NIM1 CVKVGDFGFSTVSKKGEMLNtFCGSPPYAAPELFRDEHYIG
Q8IY84 T347 Sugiyama NIM1K NIM1 GVPYPTPLEPFQLDPKHLSEtSTLKEEENEVKSTLEHLGIT
Q8IY84 T46 Sugiyama NIM1K NIM1 ESGCQTESSKEGEEGQPRQLtPFEKLTQDMSQDEKVVREIT
Q8IY84 Y204 Sugiyama NIM1K NIM1 VKHMHENQIIHRDLKAENVFyTsNtCVKVGDFGFSTVSKKG
Q8IZ83 S550 Sugiyama ALDH16A1 LFVGGRFQAPGARSSRPIRDssGNLHGYVAEGGAKDIRGAV
Q8N806 S265 Sugiyama UBR7 C14orf130 KDDVREVKVEQNsEPCAGsssEsDLQtVFKNESLNAESKSG
Q8NBJ7 S256 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG
Q8NBK3 S357 Sugiyama SUMF1 PSEC0152 UNQ3037/PRO9852 HRSYCYRYRCAARSQNTPDSsAsNLGFRCAADRLPtMD___
Q8NE71 S287 Sugiyama ABCF1 ABC50 YERQVASLKAANAAENDFsVsQAEMSsRQAMLENASDIKLE
Q8NFQ8 S135 Sugiyama TOR1AIP2 IFRG15 LULL1 PDPsHsPsDKVGRADAHLGsssVALPKEASDGTGASQEPPt
Q8TCG1 S705 Sugiyama CIP2A KIAA1524 KNEELSVLLKAQQVESERAQsDIEHLFQHNRKLESVAEEHE
Q8TDD1 S624 Sugiyama DDX54 FQQGQQGRQEQQEGPVGPAPsRPALQEKQPEKEEEEEAGEs
Q8WU90 S351 Sugiyama ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 DIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLsEAs
Q8WUM4 S381 Sugiyama PDCD6IP AIP1 ALIX KIAA1375 VSVQQSLAAYNQRKADLVNRsIAQMREATTLANGVLASLNL
Q8WUM4 S632 Sugiyama PDCD6IP AIP1 ALIX KIAA1375 TTKVQESLKKQEGLLKNIQVsHQEFSKMKQsNNEANLREEV
Q8WWH5 S268 Sugiyama TRUB1 PUS4 ECGGGFYIRSLVSDIGKELSsCANVLELTRTKQGPFTLEEH
Q8WWI1 S704 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 KKRLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEM
Q8WWI1 S706 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 RLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEMQK
Q8WX93 S595 Sugiyama PALLD KIAA0992 CGI-151 ELASKKPSEIQQVNNPELGLsRAALQMQFNAAERETNGVHP
Q8WXH0 S2781 Sugiyama SYNE2 KIAA1011 NUA ILSQIRKCKVTHDGILARQQsVEsLAEEVKDKVPSLTTYEG
Q92499 S541 Sugiyama DDX1 NLEQYFIQQGGGPDKKGHQFsCVCLHGDRKPHERKQNLERF
Q92626 S1300 Sugiyama PXDN KIAA0230 MG50 PRG2 PXD01 VPO VPO1 NITRVQSDVFRVAEFPHGyGsCDEIPRVDLRVWQDCCEDCR
Q92734 S183 Sugiyama TFG AsMsAFDPLKNQDEINKNVMsAFGLtDDQVsGPPsAPAEDR
Q92851 S216 Sugiyama CASP10 MCH4 IVTPPVDKEAESYQGEEELVsQTDVKTFLEALPQESWQNKH
Q92973 S339 Sugiyama TNPO1 KPNB2 MIP1 TRN SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE
Q92974 S711 Sugiyama ARHGEF2 KIAA0651 LFP40 sGGNtsPGVtANGEARTFNGsIELCRADsDssQRDRNGNQL
Q93062 S14 Sugiyama RBPMS HERMES _______MNNGGKAEKENtPsEANLQEEEVRTLFVSGLPLD
Q969G3 S316 Sugiyama SMARCE1 BAF57 ARKRQEEREKEAAEQAERsQssIVPEEEQAANKGEEKKDDE
Q96A72 S108 Sugiyama MAGOHB MAGOH2 QELEIVIGDEHISFTTSKIGsLIDVNQSKDPEGLRVFYYLV
Q96AC1 S666 Sugiyama FERMT2 KIND2 MIG2 PLEKHC1 VHEFIGGYIFLSTRAKDQNEsLDEEMFyKLTSGWV______
Q96AY3 S207 Sugiyama FKBP10 FKBP65 PSEC0056 DGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGMCPGERR
Q96CU9 S357 Sugiyama FOXRED1 FP634 LETPLVADTSGAYFRREGLGsNYLGGRSPTEQEEPDPANLE
Q96D15 S76 Sugiyama RCN3 UNQ239/PRO272 HEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGDGDGW
Q96EP5 S208 Sugiyama DAZAP1 AEPRDsKsQAPGQPGAsQWGsRVVPNAANGWAGQPPPTWQQ
Q96FC9 S277 Sugiyama DDX11 CHL1 CHLR1 KRG2 LVSLGSRQNLCVNEDVKSLGsVQLINDRCVDMQRSRHEKKK
Q96JJ3 S503 Sugiyama ELMO2 CED12A KIAA1834 RALPSKPNSLDQFKSKLRsLsYsEILRLRQSERMSQDDFQS
Q96JP5 S177 Sugiyama ZFP91 ZNF757 FKSG11 TSVSRHRDTENTRSSRSKTGsLQLICKSEPNTDQLDYDVGE
Q96KP4 S58 Sugiyama CNDP2 CN2 CPGL HEL-S-13 PEPA RGEIRRMMEVAAADVKQLGGsVELVDIGKQKLPDGSEIPLP
Q96N67 S1432 Sugiyama DOCK7 KIAA1771 RRSRGQLGTYTIAsPPERsPsGsAFGsQENLRWRKDMTHWR
Q96N67 S1438 Sugiyama DOCK7 KIAA1771 LGTYTIAsPPERsPsGsAFGsQENLRWRKDMTHWRQNTEKL
Q96P16 S285 Sugiyama RPRD1A P15RS YKRKLARVSLVRKELRSRIQsLPDLSRLPNVTGSHMHLPFA
Q96S59 S181 Sugiyama RANBP9 RANBPM QEtPLPRSWsPKDKFsYIGLsQNNLRVHYKGHGKTPKDAAS
Q99426 S163 Sugiyama TBCB CG22 CKAP1 AEAAQRLAEEKAQASSIPVGsRCEVRAAGQSPRRGTVMYVG
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99798 S79 Sugiyama ACO2 LNRPLTLSEKIVyGHLDDPAsQEIERGKSYLRLRPDRVAMQ
Q99829 S130 Sugiyama CPNE1 CPN1 LTLPLMLKPGKPAGRGTITVsAQELKDNRVVTMEVEARNLD
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3 S54 Sugiyama TUBA1C TUBA6 GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV
Q9BT78 S297 Sugiyama COPS4 CSN4 QLQEFAAMLMPHQKATTADGssILDRAVIEHNLLSASKLYN
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BVS4 S412 Sugiyama RIOK2 RIO2 EMTEFNQALEEIKGQVVENNsVTEFsEEKNRTENYNRQDGQ
Q9BWG6 S199 Sugiyama SCNM1 PAPMsPtRRRALDHyLTLRSsGWIPDGRGRWVKDENVEFDs
Q9BX40 S165 Sugiyama LSM14B C20orf40 FAM61B RAP55B GFPSIPVGKsPMVEQAVQtGsADNLNAKKLLPGKGTTGTQL
Q9BYX7 S239 Sugiyama POTEKP ACTBL3 FKSG30 VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BZK7 S506 Sugiyama TBL1XR1 IRA1 TBLR1 IFEVCWNAAGDKVGASASDGsVCVLDLRK____________
Q9C0C2 S1229 Sugiyama TNKS1BP1 KIAA1741 TAB182 LESGGSEEPGGIGVGEKDWtsDVNVKSKDLAEVGEGGGHsQ
Q9C0C2 S214 Sugiyama TNKS1BP1 KIAA1741 TAB182 ssRYGPRTyGtTTAPRDEDGstLFRGWsQEGPVKsPAECRE
Q9C0C2 S724 Sugiyama TNKS1BP1 KIAA1741 TAB182 GAELKDtQsPstCsEGLLGWsQKDLQSEFGITGDPQPssFs
Q9H0H5 S257 Sugiyama RACGAP1 KIAA1478 MGCRACGAP ETVPYWtRSRRKtGtLQPWNsDstLNSRQLEPRTETDsVGt
Q9H2J4 S151 Sugiyama PDCL3 PhLP2A VIAF1 NQHLSGLARKFPDVKFIKAIsTTCIPNYPDRNLPTIFVYLE
Q9H3N1 S228 Sugiyama TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 PSKRRRPQPYPYPSKKLLsEsAQPLKKVEEEQEADEEDVsE
Q9H3N1 S270 Sugiyama TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 EAEsKEGtNKDFPQNAIRQRsLGPsLAtDKs__________
Q9H501 Y72 Sugiyama ESF1 ABTAP C20orf6 HDCMC28P AVDKRGRPISHSTTEDLKRFyDLsDsDsNLsGEDSKALSQK
Q9H6H4 S152 Sugiyama REEP4 C8orf20 PP432 AAVQAATKSQGALAGRLRsFsMQDLRSISDAPAPAyHDPLy
Q9H788 S129 Sugiyama SH2D4A PPP1R38 SH2A EAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKDIWKKV
Q9HCD5 S378 Sugiyama NCOA5 KIAA1637 EETDKIINYLRERKERLMRsstDsLPGPISRQPLGATSGAS
Q9HCD6 S235 Sugiyama TANC2 KIAA1148 KIAA1636 QSQKSSMDSCLYRVDENMTAstYsLNKIPERNLEtVLsQsV
Q9HCN4 S301 Sugiyama GPN1 MBDIN RPAP4 XAB1 HUSSY-23 ANAESQQQREQLERLRKDMGsVALDAGtAKDsLsPVLHPsD
Q9HCN8 S40 Sugiyama SDF2L1 UNQ1941/PRO4424 ALLVPGGGAAKTGAELVTCGsVLKLLNTHHRVRLHSHDIKY
Q9HD42 S101 Sugiyama CHMP1A CHMP1 KIAA0047 PCOLN3 PRSM1 TMKGVTKNMAQVTKALDKALsTMDLQKVSSVMDRFEQQVQN
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQR4 S244 Sugiyama NIT2 CUA002 VVNPWGEVLAKAGTEEAIVYsDIDLKKLAEIRQQIPVFRQK
Q9NRY5 S209 Sugiyama FAM114A2 C5orf3 AEGDPGFKRTKGLMNRNATLsQVLREAKEKEEIRTSNEVTV
Q9NSE4 S176 Sugiyama IARS2 HGLPIEIKVLSELGREAQNLsAMEIRKKARSFAKAAIEKQK
Q9NTX5 S113 Sugiyama ECHDC1 LENWTEGKGLIVRGAKNTFSsGSDLNAVKSLGTPEDGMAVC
Q9NWS0 S175 Sugiyama PIH1D1 NOP17 NLQLNPEWRMMKNRPFMGsIsQQNIRSEQRPRIQELGDLyt
Q9NWU1 S108 Sugiyama OXSM VAAYVPRGSDEGQFNEQNFVsKSDIKSMSSPTIMAIGAAEL
Q9NY33 S190 Sugiyama DPP3 TYFSGNCTMEDAKLAQDFLDsQNLsAyNtRLFKEVDGEGKP
Q9NYB9 S22 Sugiyama ABI2 ARGBPIA AELQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSAD
Q9NYL9 S25 Sugiyama TMOD3 FRKDLEKyKDLDEDELLGNLsEtELKQLETVLDDLDPENAL
Q9NYU2 S366 Sugiyama UGGT1 GT UGCGL1 UGGT UGT1 UGTR MKDLSQNFPTKARAITKTAVsSELRtEVEENQKYFKGTLGL
Q9NZB2 S417 Sugiyama FAM120A C9orf10 KIAA0183 OSSA LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERssPI
Q9NZB2 S990 Sugiyama FAM120A C9orf10 KIAA0183 OSSA FPLQVVSVGGPARGRPRGVIstPVIRTFGRGGRYYGRGYKN
Q9NZL9 S110 Sugiyama MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 IVHCAAERRPDVVENQPDAAsQLNVDASGNLAKEAAAVGAF
Q9NZM1 S174 Sugiyama MYOF FER1L3 KIAA1207 EDRLDNAVRGPGPKGPVGtVsEAQLARRLtKVKNSRRMLSN
Q9P265 S203 Sugiyama DIP2B KIAA1463 stsssASSTLSHGEVKGtsGsLADVFANtRIENFSAPPDVT
Q9UGV2 S333 Sugiyama NDRG3 MGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsD
Q9UGV2 S338 Sugiyama NDRG3 SASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsDGtQES
Q9UHV9 S22 Sugiyama PFDN2 PFD2 HSPC231 AENSGRAGKssGSGAGKGAVsAEQVIAGFNRLRQEQRGLAS
Q9UI15 S185 Sugiyama TAGLN3 NP25 EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______
Q9UII2 S63 Sugiyama ATP5IF1 ATPI ATPIF1 AGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEIVHHKK
Q9UIQ6 S51 Sugiyama LNPEP OTASE AKEPCLHPLEPDEVEyEPRGsRLLVRGLGEHEMEEDEEDyE
Q9UKX7 S227 Sugiyama NUP50 NPAP60L PRO1146 NsESEsNKVAAEtQsPsLFGstKLQQEStFLFHGNKTEDtP
Q9UKX7 S52 Sugiyama NUP50 NPAP60L PRO1146 EEVLKNRAIKKAKRRNVGFEsDtGGAFKGFKGLVVPSGGGR
Q9UNH7 S316 Sugiyama SNX6 LKYYLRESQAAKDLLYRRsRsLVDYENANKALDKARAKNKD
Q9UNZ2 S74 Sugiyama NSFL1C UBXN2C SQATPssVsRGTAPSDNRVtsFRDLIHDQDEDEEEEEGQRF
Q9UPQ0 S201 Sugiyama LIMCH1 KIAA1102 DCWDsERsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVV
Q9UPQ0 S210 Sugiyama LIMCH1 KIAA1102 sLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRGssDGRG
Q9UPR0 T584 Sugiyama PLCL2 KIAA1092 PLCE2 KILIKAKKLsSNCSGVEGDVtDEDEGAEMSQRMGKENMEQP
Q9UQ35 S2692 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS
Q9Y2B0 S115 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF
Q9Y2B0 S116 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA
Q9Y2B0 S63 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2B0 T79 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGEQIDPs
Q9Y2L1 S633 Sugiyama DIS3 KIAA1008 RRP44 LNKLAKILKKRRIEKGALTLssPEVRFHMDSETHDPIDLQT
Q9Y394 S328 Sugiyama DHRS7 DHRS7A RETSDR4 SDR34C1 CGI-86 UNQ285/PRO3448 ITNKMGKKRIENFKSGVDADssyFKIFKTKHD_________
Q9Y3S2 S25 Sugiyama ZNF330 NOA36 KTGARKKAENRREREKQLRAsRstIDLAKHPCNASMECDKC
Q9Y3S2 S27 Sugiyama ZNF330 NOA36 GARKKAENRREREKQLRAsRstIDLAKHPCNASMECDKCQR
Q9Y3S2 T28 Sugiyama ZNF330 NOA36 ARKKAENRREREKQLRAsRstIDLAKHPCNASMECDKCQRR
Q9Y3U8 S91 Sugiyama RPL36 KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______
Q9Y490 S1535 Sugiyama TLN1 KIAA1027 TLN RTTNPTAKRQFVQSAKEVANsTANLVKTIKALDGAFTEENR
Q9Y4G6 S1537 Sugiyama TLN2 KIAA0320 KTANPVAKRHFVQSAKEVANsTANLVKTIKALDGDFSEDNR
Q9Y4X5 S517 Sugiyama ARIH1 ARI MOP6 UBCH7BP HUSSY-27 DLENATEVLSGYLERDIsQDsLQDIKQKVQDKYRYCESRRR
Q9Y6E0 S400 Sugiyama STK24 MST3 STK3 ISPLFAELKEKsQACGGNLGsIEELRGAIYLAEEACPGISD
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Signal Transduction R-HSA-162582 1.684404e-10 9.774 0 0
Cell Cycle R-HSA-1640170 3.874670e-09 8.412 0 0
Cell Cycle, Mitotic R-HSA-69278 8.814827e-08 7.055 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 9.570668e-08 7.019 0 0
Axon guidance R-HSA-422475 1.443987e-06 5.840 0 0
Apoptotic execution phase R-HSA-75153 2.041067e-06 5.690 0 0
Cell Cycle Checkpoints R-HSA-69620 2.708408e-06 5.567 0 0
M Phase R-HSA-68886 8.556841e-06 5.068 0 0
Nervous system development R-HSA-9675108 9.933570e-06 5.003 0 0
Mitotic Prometaphase R-HSA-68877 1.845283e-05 4.734 0 0
Apoptosis R-HSA-109581 3.825116e-05 4.417 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.909031e-05 4.408 0 0
Semaphorin interactions R-HSA-373755 5.103672e-05 4.292 0 0
Intracellular signaling by second messengers R-HSA-9006925 6.950807e-05 4.158 0 0
NRAGE signals death through JNK R-HSA-193648 8.100040e-05 4.092 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 9.214666e-05 4.036 0 0
Cellular Senescence R-HSA-2559583 1.022897e-04 3.990 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.456772e-04 3.837 0 0
Programmed Cell Death R-HSA-5357801 1.513164e-04 3.820 0 0
Signaling by NTRKs R-HSA-166520 1.957887e-04 3.708 0 0
Cellular responses to stress R-HSA-2262752 2.009281e-04 3.697 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.333403e-04 3.632 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.505360e-04 3.601 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.505360e-04 3.601 0 0
Cellular responses to stimuli R-HSA-8953897 2.781053e-04 3.556 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.951836e-04 3.530 0 0
PIP3 activates AKT signaling R-HSA-1257604 3.275333e-04 3.485 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.224882e-04 3.491 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.519348e-04 3.454 0 0
G alpha (12/13) signalling events R-HSA-416482 3.497905e-04 3.456 0 0
Death Receptor Signaling R-HSA-73887 3.940704e-04 3.404 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 4.524674e-04 3.344 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 5.890913e-04 3.230 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 6.188058e-04 3.208 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 6.356132e-04 3.197 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 7.370155e-04 3.133 0 0
G2/M DNA damage checkpoint R-HSA-69473 9.380421e-04 3.028 0 0
ESR-mediated signaling R-HSA-8939211 1.016811e-03 2.993 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.091706e-03 2.962 0 0
Separation of Sister Chromatids R-HSA-2467813 1.135876e-03 2.945 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.192025e-03 2.924 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.240577e-03 2.906 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.219700e-03 2.914 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.260847e-03 2.899 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.331321e-03 2.876 0 0
Post NMDA receptor activation events R-HSA-438064 1.584801e-03 2.800 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.848503e-03 2.733 0 0
Signaling by PTK6 R-HSA-8848021 1.848503e-03 2.733 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.163508e-03 2.665 0 0
Mitotic Anaphase R-HSA-68882 2.124203e-03 2.673 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.047380e-03 2.689 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.184796e-03 2.661 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.163508e-03 2.665 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.199468e-03 2.658 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 2.303790e-03 2.638 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.341652e-03 2.630 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 2.533104e-03 2.596 0 0
Kinesins R-HSA-983189 2.579852e-03 2.588 0 0
Integrin signaling R-HSA-354192 2.781987e-03 2.556 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.955320e-03 2.529 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 3.122953e-03 2.505 0 0
Signaling by Hippo R-HSA-2028269 3.276334e-03 2.485 0 0
EPH-Ephrin signaling R-HSA-2682334 3.439487e-03 2.464 0 0
DNA Double Strand Break Response R-HSA-5693606 3.392533e-03 2.469 0 0
L1CAM interactions R-HSA-373760 3.461959e-03 2.461 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 3.763430e-03 2.424 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.960562e-03 2.402 0 0
Interleukin-37 signaling R-HSA-9008059 3.960562e-03 2.402 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 3.995907e-03 2.398 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 4.354069e-03 2.361 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.334495e-03 2.363 0 0
Signaling by Nuclear Receptors R-HSA-9006931 4.364789e-03 2.360 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.521848e-03 2.345 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 4.782770e-03 2.320 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.942515e-03 2.306 0 0
MAPK family signaling cascades R-HSA-5683057 5.241644e-03 2.281 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 6.148176e-03 2.211 0 0
PKMTs methylate histone lysines R-HSA-3214841 6.194286e-03 2.208 0 0
Prolonged ERK activation events R-HSA-169893 6.148176e-03 2.211 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.286567e-03 2.202 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.377479e-03 2.195 0 0
G2/M Checkpoints R-HSA-69481 6.474338e-03 2.189 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 6.576691e-03 2.182 0 0
Signaling by ALK in cancer R-HSA-9700206 6.576691e-03 2.182 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 7.365447e-03 2.133 0 0
Signaling by RAF1 mutants R-HSA-9656223 7.338169e-03 2.134 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 7.213546e-03 2.142 0 0
Signaling downstream of RAS mutants R-HSA-9649948 7.213546e-03 2.142 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 7.213546e-03 2.142 0 0
Signaling by RAS mutants R-HSA-6802949 7.213546e-03 2.142 0 0
Breakdown of the nuclear lamina R-HSA-352238 7.927662e-03 2.101 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 8.105957e-03 2.091 0 0
Meiosis R-HSA-1500620 8.492036e-03 2.071 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 8.389592e-03 2.076 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 9.077472e-03 2.042 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 9.077472e-03 2.042 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 9.077472e-03 2.042 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 9.077472e-03 2.042 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 8.673793e-03 2.062 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 8.673793e-03 2.062 0 0
MyD88-independent TLR4 cascade R-HSA-166166 8.901060e-03 2.051 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 8.901060e-03 2.051 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 9.633410e-03 2.016 0 0
Membrane Trafficking R-HSA-199991 9.744601e-03 2.011 0 0
Long-term potentiation R-HSA-9620244 1.000372e-02 2.000 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.049750e-02 1.979 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.104991e-02 1.957 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.127362e-02 1.948 0 0
Cell-Cell communication R-HSA-1500931 1.155906e-02 1.937 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.177329e-02 1.929 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.220207e-02 1.914 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.163078e-02 1.934 0 0
Signaling by ERBB2 R-HSA-1227986 1.173057e-02 1.931 0 0
Signalling to ERKs R-HSA-187687 1.241473e-02 1.906 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 1.223904e-02 1.912 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.204384e-02 1.919 0 0
Oncogene Induced Senescence R-HSA-2559585 1.241473e-02 1.906 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.251306e-02 1.903 0 0
Homology Directed Repair R-HSA-5693538 1.309465e-02 1.883 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.337502e-02 1.874 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.368410e-02 1.864 0 0
Chromatin organization R-HSA-4839726 1.410119e-02 1.851 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.704581e-02 1.768 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.704581e-02 1.768 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.704581e-02 1.768 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.704581e-02 1.768 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.704581e-02 1.768 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.510938e-02 1.821 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.487482e-02 1.828 0 0
MAP2K and MAPK activation R-HSA-5674135 1.652952e-02 1.782 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.483131e-02 1.829 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.581176e-02 1.801 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.610817e-02 1.793 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.516756e-02 1.819 0 0
NrCAM interactions R-HSA-447038 1.516756e-02 1.819 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.704019e-02 1.769 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.705001e-02 1.768 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.705001e-02 1.768 0 0
Regulation of TP53 Activity R-HSA-5633007 1.739443e-02 1.760 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 1.759973e-02 1.754 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.899333e-02 1.721 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.939898e-02 1.712 0 0
Chromatin modifying enzymes R-HSA-3247509 1.806456e-02 1.743 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.781780e-02 1.749 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.843772e-02 1.734 0 0
Deubiquitination R-HSA-5688426 2.004134e-02 1.698 0 0
Striated Muscle Contraction R-HSA-390522 2.072719e-02 1.683 0 0
Nephrin family interactions R-HSA-373753 2.079097e-02 1.682 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.130419e-02 1.672 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 2.334987e-02 1.632 0 0
ARMS-mediated activation R-HSA-170984 2.367130e-02 1.626 0 0
ALK mutants bind TKIs R-HSA-9700645 2.367130e-02 1.626 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 2.184878e-02 1.661 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.358856e-02 1.627 0 0
GP1b-IX-V activation signalling R-HSA-430116 2.367130e-02 1.626 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 2.195924e-02 1.658 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 2.315839e-02 1.635 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.192229e-02 1.659 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 2.184878e-02 1.661 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 2.367130e-02 1.626 0 0
Interleukin-1 family signaling R-HSA-446652 2.385849e-02 1.622 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 2.437518e-02 1.613 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.506104e-02 1.601 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 2.506104e-02 1.601 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 2.528302e-02 1.597 0 0
HDMs demethylate histones R-HSA-3214842 2.553789e-02 1.593 0 0
Mitotic Prophase R-HSA-68875 2.571182e-02 1.590 0 0
Signaling by ROBO receptors R-HSA-376176 2.637770e-02 1.579 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 2.983848e-02 1.525 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 2.983848e-02 1.525 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 2.983848e-02 1.525 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 2.819443e-02 1.550 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.746594e-02 1.561 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.852436e-02 1.545 0 0
Frs2-mediated activation R-HSA-170968 2.819443e-02 1.550 0 0
Cellular response to heat stress R-HSA-3371556 2.781211e-02 1.556 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.805790e-02 1.552 0 0
DNA Repair R-HSA-73894 2.829256e-02 1.548 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.742785e-02 1.562 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.177116e-02 1.498 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 3.177116e-02 1.498 0 0
GPVI-mediated activation cascade R-HSA-114604 3.245276e-02 1.489 0 0
Centrosome maturation R-HSA-380287 3.354326e-02 1.474 0 0
ISG15 antiviral mechanism R-HSA-1169408 3.354326e-02 1.474 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.393173e-02 1.469 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 3.564778e-02 1.448 0 0
Regulation of KIT signaling R-HSA-1433559 3.564778e-02 1.448 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 3.656097e-02 1.437 0 0
Recycling pathway of L1 R-HSA-437239 3.671236e-02 1.435 0 0
Ephrin signaling R-HSA-3928664 3.694092e-02 1.432 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 3.694092e-02 1.432 0 0
Meiotic synapsis R-HSA-1221632 3.811325e-02 1.419 0 0
FOXO-mediated transcription R-HSA-9614085 4.340447e-02 1.362 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 4.249751e-02 1.372 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.957528e-02 1.403 0 0
S Phase R-HSA-69242 4.256360e-02 1.371 0 0
NGF-stimulated transcription R-HSA-9031628 4.129222e-02 1.384 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 4.055935e-02 1.392 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.383057e-02 1.358 0 0
Signaling by Interleukins R-HSA-449147 3.908597e-02 1.408 0 0
DCC mediated attractive signaling R-HSA-418885 4.426043e-02 1.354 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 4.426043e-02 1.354 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 4.426043e-02 1.354 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 4.437180e-02 1.353 0 0
Rap1 signalling R-HSA-392517 4.457672e-02 1.351 0 0
Regulation of PTEN localization R-HSA-8948747 4.650075e-02 1.333 0 0
Netrin mediated repulsion signals R-HSA-418886 4.650075e-02 1.333 0 0
TRIF-mediated programmed cell death R-HSA-2562578 4.650075e-02 1.333 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 4.650075e-02 1.333 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.744045e-02 1.324 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.744045e-02 1.324 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 5.264737e-02 1.279 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 5.264737e-02 1.279 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 5.406829e-02 1.267 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 5.107060e-02 1.292 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 4.840257e-02 1.315 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 4.840257e-02 1.315 0 0
RAF activation R-HSA-5673000 5.195890e-02 1.284 0 0
Signaling by ERBB4 R-HSA-1236394 5.322514e-02 1.274 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 5.107060e-02 1.292 0 0
Neurodegenerative Diseases R-HSA-8863678 5.107060e-02 1.292 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 5.406829e-02 1.267 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 5.259098e-02 1.279 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 4.863719e-02 1.313 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 5.161424e-02 1.287 0 0
NOD1/2 Signaling Pathway R-HSA-168638 5.195890e-02 1.284 0 0
Activation of RAC1 R-HSA-428540 5.264737e-02 1.279 0 0
Heme signaling R-HSA-9707616 5.305073e-02 1.275 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 6.158357e-02 1.211 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 6.158357e-02 1.211 0 0
IKBKB deficiency causes SCID R-HSA-5602636 6.158357e-02 1.211 0 0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 6.158357e-02 1.211 0 0
TRAF3 deficiency - HSE R-HSA-5602571 6.158357e-02 1.211 0 0
Type I hemidesmosome assembly R-HSA-446107 6.154253e-02 1.211 0 0
Regulation by c-FLIP R-HSA-3371378 6.154253e-02 1.211 0 0
Dimerization of procaspase-8 R-HSA-69416 6.154253e-02 1.211 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 6.154253e-02 1.211 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 6.374200e-02 1.196 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 6.274187e-02 1.202 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 5.637029e-02 1.249 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 5.776167e-02 1.238 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 5.776167e-02 1.238 0 0
Eukaryotic Translation Elongation R-HSA-156842 6.092125e-02 1.215 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 6.452438e-02 1.190 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 6.144942e-02 1.211 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 6.452438e-02 1.190 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 6.452438e-02 1.190 0 0
G2/M Transition R-HSA-69275 6.292504e-02 1.201 0 0
Neurexins and neuroligins R-HSA-6794361 6.360528e-02 1.197 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 5.573092e-02 1.254 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 5.992782e-02 1.222 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 5.761820e-02 1.239 0 0
RAF/MAP kinase cascade R-HSA-5673001 5.687617e-02 1.245 0 0
Cell junction organization R-HSA-446728 6.317117e-02 1.199 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 6.154253e-02 1.211 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 6.492130e-02 1.188 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 6.509127e-02 1.186 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 6.548359e-02 1.184 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 6.548359e-02 1.184 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 6.548359e-02 1.184 0 0
IRAK1 recruits IKK complex R-HSA-937039 6.548359e-02 1.184 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 6.548359e-02 1.184 0 0
Diseases of programmed cell death R-HSA-9645723 6.684574e-02 1.175 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 6.768812e-02 1.169 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 6.831666e-02 1.165 0 0
G2 Phase R-HSA-68911 6.848621e-02 1.164 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 6.848621e-02 1.164 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 6.848621e-02 1.164 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 6.848621e-02 1.164 0 0
MITF-M-dependent gene expression R-HSA-9856651 7.090545e-02 1.149 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 7.560446e-02 1.121 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 7.883743e-02 1.103 0 0
CASP8 activity is inhibited R-HSA-5218900 7.883743e-02 1.103 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 7.733332e-02 1.112 0 0
Notch-HLH transcription pathway R-HSA-350054 8.474492e-02 1.072 0 0
Interaction between L1 and Ankyrins R-HSA-445095 7.852073e-02 1.105 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 8.185207e-02 1.087 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.593732e-02 1.120 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.593732e-02 1.120 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 7.769334e-02 1.110 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 8.170247e-02 1.088 0 0
Synaptic adhesion-like molecules R-HSA-8849932 9.078286e-02 1.042 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 7.975717e-02 1.098 0 0
Polo-like kinase mediated events R-HSA-156711 9.078286e-02 1.042 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 7.883743e-02 1.103 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 8.872637e-02 1.052 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 7.991010e-02 1.097 0 0
Apoptotic factor-mediated response R-HSA-111471 9.078286e-02 1.042 0 0
mTORC1-mediated signalling R-HSA-166208 8.474492e-02 1.072 0 0
Toll-like Receptor Cascades R-HSA-168898 8.116542e-02 1.091 0 0
Protein-protein interactions at synapses R-HSA-6794362 7.923832e-02 1.101 0 0
Muscle contraction R-HSA-397014 8.914316e-02 1.050 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 8.474492e-02 1.072 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 7.991010e-02 1.097 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 9.078286e-02 1.042 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 7.852073e-02 1.105 0 0
Reproduction R-HSA-1474165 8.933957e-02 1.049 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 8.521046e-02 1.070 0 0
IRE1alpha activates chaperones R-HSA-381070 8.965238e-02 1.047 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 9.141729e-02 1.039 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.166809e-02 1.038 0 0
XBP1(S) activates chaperone genes R-HSA-381038 9.179063e-02 1.037 0 0
TRAIL signaling R-HSA-75158 9.300897e-02 1.031 0 0
GLI proteins bind promoters of Hh responsive genes to promote transcription R-HSA-5635851 9.300897e-02 1.031 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 9.300897e-02 1.031 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 9.300897e-02 1.031 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 9.300897e-02 1.031 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 9.300897e-02 1.031 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 9.300897e-02 1.031 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.248810e-01 0.904 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 1.248810e-01 0.904 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 1.248810e-01 0.904 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.248810e-01 0.904 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 1.248810e-01 0.904 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 1.248810e-01 0.904 0 0
mRNA Editing: A to I Conversion R-HSA-75064 1.005302e-01 0.998 0 0
Regulation of TP53 Expression R-HSA-6804754 1.005302e-01 0.998 0 0
Diseases of Cellular Senescence R-HSA-9630747 1.005302e-01 0.998 0 0
Diseases of cellular response to stress R-HSA-9675132 1.005302e-01 0.998 0 0
C6 deamination of adenosine R-HSA-75102 1.005302e-01 0.998 0 0
Potassium transport channels R-HSA-1296067 1.005302e-01 0.998 0 0
MET interacts with TNS proteins R-HSA-8875513 1.443863e-01 0.840 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.443863e-01 0.840 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 1.507188e-01 0.822 0 0
CHL1 interactions R-HSA-447041 1.507188e-01 0.822 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.507188e-01 0.822 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 1.507188e-01 0.822 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 1.429494e-01 0.845 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 1.429494e-01 0.845 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.429494e-01 0.845 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.133518e-01 0.946 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.133518e-01 0.946 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.133518e-01 0.946 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 1.133518e-01 0.946 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 1.054137e-01 0.977 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 1.322202e-01 0.879 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 1.211859e-01 0.917 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 1.211859e-01 0.917 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 1.211859e-01 0.917 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 1.211859e-01 0.917 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.523916e-01 0.817 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.380474e-01 0.860 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 1.380474e-01 0.860 0 0
Late endosomal microautophagy R-HSA-9615710 1.009003e-01 0.996 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.009003e-01 0.996 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.250242e-01 0.903 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.250242e-01 0.903 0 0
Activation of the pre-replicative complex R-HSA-68962 1.132979e-01 0.946 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 1.132979e-01 0.946 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.559353e-01 0.807 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.559353e-01 0.807 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 1.027645e-01 0.988 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 1.027645e-01 0.988 0 0
MET promotes cell motility R-HSA-8875878 1.527429e-01 0.816 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.099755e-01 0.959 0 0
Translation initiation complex formation R-HSA-72649 1.319955e-01 0.879 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.540917e-01 0.812 0 0
Nuclear Receptor transcription pathway R-HSA-383280 1.193354e-01 0.923 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.169691e-01 0.932 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 1.284545e-01 0.891 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.245087e-01 0.905 0 0
Regulation of necroptotic cell death R-HSA-5675482 1.550873e-01 0.809 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 1.402808e-01 0.853 0 0
Co-stimulation by CD28 R-HSA-389356 1.348179e-01 0.870 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 1.237472e-01 0.907 0 0
Ion homeostasis R-HSA-5578775 1.540917e-01 0.812 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 9.721918e-02 1.012 0 0
DARPP-32 events R-HSA-180024 1.009003e-01 0.996 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.324551e-01 0.878 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.324551e-01 0.878 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 1.380474e-01 0.860 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.496683e-01 0.825 0 0
Regulated Necrosis R-HSA-5218859 1.452698e-01 0.838 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.324551e-01 0.878 0 0
Platelet calcium homeostasis R-HSA-418360 1.009003e-01 0.996 0 0
TGFBR3 expression R-HSA-9839394 1.250242e-01 0.903 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.414554e-01 0.849 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 1.142604e-01 0.942 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 1.392689e-01 0.856 0 0
RET signaling R-HSA-8853659 1.264343e-01 0.898 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.550873e-01 0.809 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 1.527429e-01 0.816 0 0
Peptide chain elongation R-HSA-156902 1.055490e-01 0.977 0 0
Activation of BH3-only proteins R-HSA-114452 1.132979e-01 0.946 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.299052e-01 0.886 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 9.452266e-02 1.024 0 0
Selective autophagy R-HSA-9663891 1.055490e-01 0.977 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.258052e-01 0.900 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.299052e-01 0.886 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 1.519915e-01 0.818 0 0
Netrin-1 signaling R-HSA-373752 9.372208e-02 1.028 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.098608e-01 0.959 0 0
CREB phosphorylation R-HSA-199920 1.205775e-01 0.919 0 0
Sodium/Calcium exchangers R-HSA-425561 1.429494e-01 0.845 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 1.241432e-01 0.906 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 1.519915e-01 0.818 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.106609e-01 0.956 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.098608e-01 0.959 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 1.117708e-01 0.952 0 0
TRP channels R-HSA-3295583 1.402808e-01 0.853 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.201118e-01 0.920 0 0
Signaling by WNT R-HSA-195721 1.072606e-01 0.970 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 9.827593e-02 1.008 0 0
Mitochondrial calcium ion transport R-HSA-8949215 1.559353e-01 0.807 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.011407e-01 0.995 0 0
MAP kinase activation R-HSA-450294 1.391046e-01 0.857 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.472975e-01 0.832 0 0
Formation of the anterior neural plate R-HSA-9823739 1.133518e-01 0.946 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 1.550873e-01 0.809 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.495354e-01 0.825 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 1.458476e-01 0.836 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.195954e-01 0.922 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 1.550873e-01 0.809 0 0
Signaling by SCF-KIT R-HSA-1433557 1.497650e-01 0.825 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.523916e-01 0.817 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.142604e-01 0.942 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.322202e-01 0.879 0 0
DAG and IP3 signaling R-HSA-1489509 1.031918e-01 0.986 0 0
FasL/ CD95L signaling R-HSA-75157 1.443863e-01 0.840 0 0
Neuronal System R-HSA-112316 1.230642e-01 0.910 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 1.205775e-01 0.919 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.141101e-01 0.943 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 1.550873e-01 0.809 0 0
Signaling by TGFBR3 R-HSA-9839373 1.132022e-01 0.946 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 9.400271e-02 1.027 0 0
SARS-CoV-2-host interactions R-HSA-9705683 9.965942e-02 1.001 0 0
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization R-HSA-180897 1.005302e-01 0.998 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 1.443863e-01 0.840 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.559353e-01 0.807 0 0
PECAM1 interactions R-HSA-210990 1.197073e-01 0.922 0 0
STING mediated induction of host immune responses R-HSA-1834941 1.054137e-01 0.977 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.434609e-02 1.025 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.284545e-01 0.891 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.166656e-01 0.933 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 1.563885e-01 0.806 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.563885e-01 0.806 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.563885e-01 0.806 0 0
Interleukin-12 signaling R-HSA-9020591 1.607111e-01 0.794 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 2.341731e-01 0.630 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 2.341731e-01 0.630 0 0
Diseases of Telomere Maintenance R-HSA-9673013 2.341731e-01 0.630 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 2.341731e-01 0.630 0 0
Defective Mismatch Repair Associated With PMS2 R-HSA-5632987 2.341731e-01 0.630 0 0
Defective SLC26A4 causes Pendred syndrome (PDS) R-HSA-5619046 2.341731e-01 0.630 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 2.341731e-01 0.630 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 2.341731e-01 0.630 0 0
TICAM1 deficiency - HSE R-HSA-5602566 2.341731e-01 0.630 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 2.341731e-01 0.630 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 2.341731e-01 0.630 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 2.341731e-01 0.630 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 2.341731e-01 0.630 0 0
Defective Mismatch Repair Associated With MLH1 R-HSA-5545483 2.341731e-01 0.630 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 2.341731e-01 0.630 0 0
Regulation of gap junction activity R-HSA-191650 1.913195e-01 0.718 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.913195e-01 0.718 0 0
Signaling by MAP2K mutants R-HSA-9652169 1.913195e-01 0.718 0 0
ARL13B-mediated ciliary trafficking of INPP5E R-HSA-5624958 3.298215e-01 0.482 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 3.298215e-01 0.482 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 3.298215e-01 0.482 0 0
Mitochondrial transcription initiation R-HSA-163282 3.298215e-01 0.482 0 0
Intestinal infectious diseases R-HSA-8942233 3.298215e-01 0.482 0 0
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420 3.298215e-01 0.482 0 0
Defective GFPT1 causes CMSTA1 R-HSA-4085023 3.298215e-01 0.482 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 3.298215e-01 0.482 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 3.298215e-01 0.482 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 3.298215e-01 0.482 0 0
MyD88 deficiency (TLR5) R-HSA-5602680 3.298215e-01 0.482 0 0
TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P R-HSA-6791462 3.298215e-01 0.482 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 3.298215e-01 0.482 0 0
Defective HK1 causes hexokinase deficiency (HK deficiency) R-HSA-5619056 3.298215e-01 0.482 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 3.298215e-01 0.482 0 0
TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P R-HSA-6791055 3.298215e-01 0.482 0 0
XAV939 stabilizes AXIN R-HSA-5545619 3.298215e-01 0.482 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 3.298215e-01 0.482 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.398782e-01 0.620 0 0
IRS activation R-HSA-74713 2.398782e-01 0.620 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 2.398782e-01 0.620 0 0
RSK activation R-HSA-444257 1.829465e-01 0.738 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 1.829465e-01 0.738 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.829465e-01 0.738 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.829465e-01 0.738 0 0
Lipophagy R-HSA-9613354 2.167828e-01 0.664 0 0
WNT mediated activation of DVL R-HSA-201688 2.167828e-01 0.664 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 2.167828e-01 0.664 0 0
Gap junction degradation R-HSA-190873 2.167828e-01 0.664 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.889252e-01 0.539 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.889252e-01 0.539 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.889252e-01 0.539 0 0
Signaling by RNF43 mutants R-HSA-5340588 2.889252e-01 0.539 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 4.135286e-01 0.383 0 0
Essential pentosuria R-HSA-5662853 4.135286e-01 0.383 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 4.135286e-01 0.383 0 0
TWIK related potassium channel (TREK) R-HSA-1299503 4.135286e-01 0.383 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.940314e-01 0.712 0 0
PI3K/AKT activation R-HSA-198203 2.517723e-01 0.599 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 2.517723e-01 0.599 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.737516e-01 0.760 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 2.214251e-01 0.655 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 2.214251e-01 0.655 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 2.214251e-01 0.655 0 0
Removal of the Flap Intermediate R-HSA-69166 2.214251e-01 0.655 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 3.375815e-01 0.472 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 3.375815e-01 0.472 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.961749e-01 0.707 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 1.961749e-01 0.707 0 0
ChREBP activates metabolic gene expression R-HSA-163765 2.874925e-01 0.541 0 0
Formation of the posterior neural plate R-HSA-9832991 2.874925e-01 0.541 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 2.874925e-01 0.541 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 2.874925e-01 0.541 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 2.497502e-01 0.602 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.497502e-01 0.602 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 2.497502e-01 0.602 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.195291e-01 0.659 0 0
Phosphorylation of the APC/C R-HSA-176412 2.787823e-01 0.555 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 2.787823e-01 0.555 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 3.235590e-01 0.490 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 3.235590e-01 0.490 0 0
Signaling by GSK3beta mutants R-HSA-5339716 3.235590e-01 0.490 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 3.851801e-01 0.414 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.851801e-01 0.414 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 3.851801e-01 0.414 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 3.851801e-01 0.414 0 0
PTK6 Expression R-HSA-8849473 3.851801e-01 0.414 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.851801e-01 0.414 0 0
Disinhibition of SNARE formation R-HSA-114516 3.851801e-01 0.414 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 3.851801e-01 0.414 0 0
SOS-mediated signalling R-HSA-112412 3.851801e-01 0.414 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 1.864703e-01 0.729 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 2.361957e-01 0.627 0 0
Aggrephagy R-HSA-9646399 1.815046e-01 0.741 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 3.083045e-01 0.511 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 3.083045e-01 0.511 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.083045e-01 0.511 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 3.083045e-01 0.511 0 0
Trafficking of AMPA receptors R-HSA-399719 2.282673e-01 0.642 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 3.596292e-01 0.444 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 3.596292e-01 0.444 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.596292e-01 0.444 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 3.596292e-01 0.444 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 3.596292e-01 0.444 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 3.596292e-01 0.444 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 3.596292e-01 0.444 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 3.596292e-01 0.444 0 0
Voltage gated Potassium channels R-HSA-1296072 2.380109e-01 0.623 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 2.803076e-01 0.552 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.381111e-01 0.471 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.381111e-01 0.471 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 3.381111e-01 0.471 0 0
Activation of RAS in B cells R-HSA-1169092 4.312265e-01 0.365 0 0
FGFR1b ligand binding and activation R-HSA-190370 4.312265e-01 0.365 0 0
MET receptor recycling R-HSA-8875656 4.312265e-01 0.365 0 0
Formation of annular gap junctions R-HSA-196025 4.312265e-01 0.365 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 2.678024e-01 0.572 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.194940e-01 0.496 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.034926e-01 0.691 0 0
CD28 dependent Vav1 pathway R-HSA-389359 3.954031e-01 0.403 0 0
PDH complex synthesizes acetyl-CoA from PYR R-HSA-9861559 3.954031e-01 0.403 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.887186e-01 0.724 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 2.882294e-01 0.540 0 0
PKA activation R-HSA-163615 3.680099e-01 0.434 0 0
PKA activation in glucagon signalling R-HSA-164378 3.680099e-01 0.434 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.454382e-01 0.462 0 0
Dual Incision in GG-NER R-HSA-5696400 3.090009e-01 0.510 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 2.937134e-01 0.532 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 3.129529e-01 0.505 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 3.300454e-01 0.481 0 0
DAP12 signaling R-HSA-2424491 3.493194e-01 0.457 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.493194e-01 0.457 0 0
Deadenylation of mRNA R-HSA-429947 3.715030e-01 0.430 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 4.306224e-01 0.366 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 4.753660e-01 0.323 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 4.753660e-01 0.323 0 0
MAPK1 (ERK2) activation R-HSA-112411 4.753660e-01 0.323 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 4.753660e-01 0.323 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 3.002898e-01 0.522 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.727063e-01 0.429 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.727063e-01 0.429 0 0
Tight junction interactions R-HSA-420029 3.975686e-01 0.401 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.898091e-01 0.538 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 4.273903e-01 0.369 0 0
Co-inhibition by CTLA4 R-HSA-389513 4.273903e-01 0.369 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 4.273903e-01 0.369 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.674322e-01 0.776 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.925301e-01 0.716 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 3.961359e-01 0.402 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 4.650693e-01 0.332 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 4.195249e-01 0.377 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 4.565663e-01 0.340 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 4.565663e-01 0.340 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 4.565663e-01 0.340 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 4.565663e-01 0.340 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 4.155619e-01 0.381 0 0
mRNA Splicing R-HSA-72172 2.470876e-01 0.607 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 4.492619e-01 0.348 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 4.492619e-01 0.348 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 4.492619e-01 0.348 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.079388e-01 0.389 0 0
Viral mRNA Translation R-HSA-192823 3.555704e-01 0.449 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 4.369452e-01 0.360 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 4.852236e-01 0.314 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 4.852236e-01 0.314 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.265864e-01 0.370 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 3.908578e-01 0.408 0 0
HIV elongation arrest and recovery R-HSA-167287 4.746909e-01 0.324 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.746909e-01 0.324 0 0
Pausing and recovery of HIV elongation R-HSA-167290 4.746909e-01 0.324 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 4.342278e-01 0.362 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 4.246327e-01 0.372 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.214480e-01 0.375 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 4.821296e-01 0.317 0 0
Neutrophil degranulation R-HSA-6798695 4.051680e-01 0.392 0 0
PTEN Regulation R-HSA-6807070 2.688820e-01 0.570 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 3.889118e-01 0.410 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 2.561870e-01 0.591 0 0
Signaling by NOTCH2 R-HSA-1980145 4.658707e-01 0.332 0 0
HATs acetylate histones R-HSA-3214847 2.234225e-01 0.651 0 0
Signaling by EGFR R-HSA-177929 2.404163e-01 0.619 0 0
G1/S Transition R-HSA-69206 1.845094e-01 0.734 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 4.582076e-01 0.339 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.195291e-01 0.659 0 0
Telomere Extension By Telomerase R-HSA-171319 3.030276e-01 0.519 0 0
Ribosome-associated quality control R-HSA-9948299 3.324046e-01 0.478 0 0
Chromosome Maintenance R-HSA-73886 4.384899e-01 0.358 0 0
p75NTR recruits signalling complexes R-HSA-209543 1.677972e-01 0.775 0 0
mRNA Editing R-HSA-75072 2.167828e-01 0.664 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 2.787823e-01 0.555 0 0
Killing mechanisms R-HSA-9664420 2.787823e-01 0.555 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 2.803076e-01 0.552 0 0
Cyclin D associated events in G1 R-HSA-69231 1.627761e-01 0.788 0 0
G1 Phase R-HSA-69236 1.627761e-01 0.788 0 0
Telomere Maintenance R-HSA-157579 4.726831e-01 0.325 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 2.787823e-01 0.555 0 0
HSF1-dependent transactivation R-HSA-3371571 1.710561e-01 0.767 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 3.814616e-01 0.419 0 0
DNA Replication Pre-Initiation R-HSA-69002 3.535106e-01 0.452 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 4.658707e-01 0.332 0 0
Signal attenuation R-HSA-74749 2.517723e-01 0.599 0 0
Processive synthesis on the lagging strand R-HSA-69183 2.497502e-01 0.602 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 2.257547e-01 0.646 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 4.306224e-01 0.366 0 0
Extension of Telomeres R-HSA-180786 2.863321e-01 0.543 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 3.656171e-01 0.437 0 0
Cellular response to starvation R-HSA-9711097 3.272230e-01 0.485 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 4.551998e-01 0.342 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 3.188851e-01 0.496 0 0
Nucleotide Excision Repair R-HSA-5696398 3.949447e-01 0.403 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 1.737516e-01 0.760 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.149958e-01 0.668 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.779657e-01 0.750 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 4.792932e-01 0.319 0 0
Interleukin-1 signaling R-HSA-9020702 1.755589e-01 0.756 0 0
Signaling by FGFR4 R-HSA-5654743 3.719070e-01 0.430 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 1.864703e-01 0.729 0 0
Mitophagy R-HSA-5205647 4.658707e-01 0.332 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 3.656171e-01 0.437 0 0
Regulation of mitotic cell cycle R-HSA-453276 3.656171e-01 0.437 0 0
IGF1R signaling cascade R-HSA-2428924 3.674595e-01 0.435 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 4.292872e-01 0.367 0 0
GAB1 signalosome R-HSA-180292 3.680099e-01 0.434 0 0
G0 and Early G1 R-HSA-1538133 3.961359e-01 0.402 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 1.913195e-01 0.718 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 2.167828e-01 0.664 0 0
CRMPs in Sema3A signaling R-HSA-399956 2.214251e-01 0.655 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.851801e-01 0.414 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.851801e-01 0.414 0 0
Meiotic recombination R-HSA-912446 1.710561e-01 0.767 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 3.381111e-01 0.471 0 0
Processing of SMDT1 R-HSA-8949664 3.954031e-01 0.403 0 0
Eukaryotic Translation Termination R-HSA-72764 1.821949e-01 0.739 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 2.478526e-01 0.606 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.814616e-01 0.419 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 4.427943e-01 0.354 0 0
Pyroptosis R-HSA-5620971 3.030276e-01 0.519 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 2.084133e-01 0.681 0 0
Signaling by FGFR1 R-HSA-5654736 4.821296e-01 0.317 0 0
Signaling by FGFR3 R-HSA-5654741 4.116932e-01 0.385 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 1.815046e-01 0.741 0 0
Diseases of Immune System R-HSA-5260271 1.815046e-01 0.741 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.380109e-01 0.623 0 0
Myogenesis R-HSA-525793 4.235228e-01 0.373 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 2.691068e-01 0.570 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 4.658707e-01 0.332 0 0
Opioid Signalling R-HSA-111885 3.686238e-01 0.433 0 0
Effects of PIP2 hydrolysis R-HSA-114508 1.704510e-01 0.768 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 3.978233e-01 0.400 0 0
RMTs methylate histone arginines R-HSA-3214858 1.627761e-01 0.788 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 2.352447e-01 0.628 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 2.352447e-01 0.628 0 0
p75NTR signals via NF-kB R-HSA-193639 2.497502e-01 0.602 0 0
Resolution of D-Loop Structures R-HSA-5693537 2.882294e-01 0.540 0 0
Early Phase of HIV Life Cycle R-HSA-162594 4.565663e-01 0.340 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 4.852236e-01 0.314 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 3.042521e-01 0.517 0 0
G-protein mediated events R-HSA-112040 3.034534e-01 0.518 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.913195e-01 0.718 0 0
Adrenoceptors R-HSA-390696 1.829465e-01 0.738 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 2.167828e-01 0.664 0 0
cGMP effects R-HSA-418457 2.214251e-01 0.655 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.375815e-01 0.472 0 0
Signaling by WNT in cancer R-HSA-4791275 2.477914e-01 0.606 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 2.678024e-01 0.572 0 0
Budding and maturation of HIV virion R-HSA-162588 3.727063e-01 0.429 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.265864e-01 0.370 0 0
COPI-mediated anterograde transport R-HSA-6807878 4.585549e-01 0.339 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 3.840904e-01 0.416 0 0
Nuclear RNA decay R-HSA-9930044 2.678024e-01 0.572 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 3.498666e-01 0.456 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 4.195249e-01 0.377 0 0
Platelet degranulation R-HSA-114608 3.473690e-01 0.459 0 0
Autophagy R-HSA-9612973 2.404534e-01 0.619 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.829465e-01 0.738 0 0
Repression of WNT target genes R-HSA-4641265 3.596292e-01 0.444 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 3.596292e-01 0.444 0 0
Interleukin-17 signaling R-HSA-448424 1.662668e-01 0.779 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 3.030276e-01 0.519 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 3.260628e-01 0.487 0 0
Nuclear import of Rev protein R-HSA-180746 3.090009e-01 0.510 0 0
Rab regulation of trafficking R-HSA-9007101 1.656510e-01 0.781 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 4.195249e-01 0.377 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 4.852236e-01 0.314 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 4.658707e-01 0.332 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 4.394360e-01 0.357 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.903617e-01 0.720 0 0
Signaling by NOTCH R-HSA-157118 2.020994e-01 0.694 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 4.044901e-01 0.393 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.941166e-01 0.404 0 0
Cardiac conduction R-HSA-5576891 4.060151e-01 0.391 0 0
TNF signaling R-HSA-75893 2.404163e-01 0.619 0 0
PLC beta mediated events R-HSA-112043 2.168292e-01 0.664 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 4.369452e-01 0.360 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.187201e-01 0.497 0 0
HIV Life Cycle R-HSA-162587 3.925921e-01 0.406 0 0
Inositol transporters R-HSA-429593 2.398782e-01 0.620 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 2.398782e-01 0.620 0 0
Calcineurin activates NFAT R-HSA-2025928 2.167828e-01 0.664 0 0
Transcription from mitochondrial promoters R-HSA-75944 4.135286e-01 0.383 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.214251e-01 0.655 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.909552e-01 0.719 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 3.851801e-01 0.414 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 3.083045e-01 0.511 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 4.312265e-01 0.365 0 0
TGFBR3 PTM regulation R-HSA-9839383 4.312265e-01 0.365 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 4.753660e-01 0.323 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.521674e-01 0.453 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 4.195249e-01 0.377 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.827357e-01 0.549 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 4.369452e-01 0.360 0 0
Macroautophagy R-HSA-1632852 4.489204e-01 0.348 0 0
Mitochondrial biogenesis R-HSA-1592230 4.817270e-01 0.317 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.668311e-01 0.778 0 0
MTOR signalling R-HSA-165159 2.286994e-01 0.641 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 2.124753e-01 0.673 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.497502e-01 0.602 0 0
Lagging Strand Synthesis R-HSA-69186 4.565663e-01 0.340 0 0
Gene expression (Transcription) R-HSA-74160 3.196263e-01 0.495 0 0
Interleukin-2 signaling R-HSA-9020558 2.874925e-01 0.541 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 2.579982e-01 0.588 0 0
Ca-dependent events R-HSA-111996 2.286994e-01 0.641 0 0
RNA Polymerase II Transcription R-HSA-73857 3.672078e-01 0.435 0 0
Late Phase of HIV Life Cycle R-HSA-162599 4.721422e-01 0.326 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 3.260628e-01 0.487 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 3.512921e-01 0.454 0 0
Ub-specific processing proteases R-HSA-5689880 2.157742e-01 0.666 0 0
HIV Infection R-HSA-162906 4.502249e-01 0.347 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.891770e-01 0.723 0 0
Generic Transcription Pathway R-HSA-212436 3.912173e-01 0.408 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 4.219134e-01 0.375 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 4.219134e-01 0.375 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 4.219134e-01 0.375 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 4.219134e-01 0.375 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.517723e-01 0.599 0 0
Signaling by NOTCH1 R-HSA-1980143 2.375709e-01 0.624 0 0
Calmodulin induced events R-HSA-111933 2.202985e-01 0.657 0 0
Response of endothelial cells to shear stress R-HSA-9860931 3.686238e-01 0.433 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 2.212456e-01 0.655 0 0
Signaling by VEGF R-HSA-194138 2.487201e-01 0.604 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.829465e-01 0.738 0 0
Signaling by LTK R-HSA-9842663 1.677972e-01 0.775 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 2.497502e-01 0.602 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.787823e-01 0.555 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.202985e-01 0.657 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 3.381111e-01 0.471 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 2.676255e-01 0.572 0 0
Potassium Channels R-HSA-1296071 2.676255e-01 0.572 0 0
DNA strand elongation R-HSA-69190 3.961359e-01 0.402 0 0
GPER1 signaling R-HSA-9634597 4.710699e-01 0.327 0 0
Mismatch Repair R-HSA-5358508 3.680099e-01 0.434 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.324353e-01 0.478 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.361957e-01 0.627 0 0
CaM pathway R-HSA-111997 2.202985e-01 0.657 0 0
PCP/CE pathway R-HSA-4086400 1.818627e-01 0.740 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.727063e-01 0.429 0 0
Vesicle-mediated transport R-HSA-5653656 3.827182e-01 0.417 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 2.678024e-01 0.572 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 3.509213e-01 0.455 0 0
Cellular response to chemical stress R-HSA-9711123 4.841293e-01 0.315 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 4.312265e-01 0.365 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.260628e-01 0.487 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.306224e-01 0.366 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.235228e-01 0.373 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 4.565663e-01 0.340 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 4.427943e-01 0.354 0 0
Transmission across Chemical Synapses R-HSA-112315 2.822198e-01 0.549 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 2.397860e-01 0.620 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 2.909084e-01 0.536 0 0
Protein methylation R-HSA-8876725 2.497502e-01 0.602 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 3.381111e-01 0.471 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 3.596292e-01 0.444 0 0
Host Interactions of HIV factors R-HSA-162909 4.760478e-01 0.322 0 0
Syndecan interactions R-HSA-3000170 1.944926e-01 0.711 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 3.272023e-01 0.485 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 3.560212e-01 0.449 0 0
Manipulation of host energy metabolism R-HSA-9636667 3.298215e-01 0.482 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 2.398782e-01 0.620 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.889252e-01 0.539 0 0
Defective ABCC8 can cause hypo- and hyper-glycemias R-HSA-5683177 4.135286e-01 0.383 0 0
Influenza Virus Induced Apoptosis R-HSA-168277 4.135286e-01 0.383 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.375815e-01 0.472 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.961749e-01 0.707 0 0
Ionotropic activity of kainate receptors R-HSA-451306 2.874925e-01 0.541 0 0
Protein hydroxylation R-HSA-9629569 2.436768e-01 0.613 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 3.851801e-01 0.414 0 0
Metalloprotease DUBs R-HSA-5689901 2.579982e-01 0.588 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 4.312265e-01 0.365 0 0
Co-stimulation by ICOS R-HSA-9927354 4.312265e-01 0.365 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 2.937134e-01 0.532 0 0
Unwinding of DNA R-HSA-176974 4.753660e-01 0.323 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 2.756013e-01 0.560 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 2.756013e-01 0.560 0 0
Cell-cell junction organization R-HSA-421270 4.657985e-01 0.332 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 3.188851e-01 0.496 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 3.021811e-01 0.520 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.937968e-01 0.532 0 0
Signaling by MET R-HSA-6806834 3.940666e-01 0.404 0 0
Regulation of beta-cell development R-HSA-186712 4.043029e-01 0.393 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 4.746909e-01 0.324 0 0
Signal transduction by L1 R-HSA-445144 4.273903e-01 0.369 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 2.678024e-01 0.572 0 0
Platelet sensitization by LDL R-HSA-432142 3.680099e-01 0.434 0 0
DNA Damage Reversal R-HSA-73942 4.650693e-01 0.332 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.840890e-01 0.735 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.478526e-01 0.606 0 0
TBC/RABGAPs R-HSA-8854214 3.719070e-01 0.430 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 4.342278e-01 0.362 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.711217e-01 0.430 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 3.521050e-01 0.453 0 0
Hemostasis R-HSA-109582 2.691704e-01 0.570 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.305199e-01 0.637 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.615868e-01 0.582 0 0
OAS antiviral response R-HSA-8983711 1.677972e-01 0.775 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 2.517723e-01 0.599 0 0
Nef and signal transduction R-HSA-164944 3.375815e-01 0.472 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 3.235590e-01 0.490 0 0
Uptake and function of anthrax toxins R-HSA-5210891 3.381111e-01 0.471 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 2.707345e-01 0.567 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 4.753660e-01 0.323 0 0
Interleukin-1 processing R-HSA-448706 4.753660e-01 0.323 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 4.753660e-01 0.323 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 4.427943e-01 0.354 0 0
FLT3 Signaling R-HSA-9607240 1.967310e-01 0.706 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.720202e-01 0.764 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.116932e-01 0.385 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 3.954031e-01 0.403 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.134313e-01 0.384 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 3.381111e-01 0.471 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 3.727063e-01 0.429 0 0
Interferon Signaling R-HSA-913531 4.040728e-01 0.394 0 0
Signaling by TGFB family members R-HSA-9006936 2.770661e-01 0.557 0 0
Integration of provirus R-HSA-162592 3.235590e-01 0.490 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.711294e-01 0.430 0 0
Glycolysis R-HSA-70171 1.663779e-01 0.779 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 2.889252e-01 0.539 0 0
DSCAM interactions R-HSA-376172 4.135286e-01 0.383 0 0
Synthesis of PI R-HSA-1483226 2.874925e-01 0.541 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 3.954031e-01 0.403 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 2.747728e-01 0.561 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.315744e-01 0.365 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 4.219134e-01 0.375 0 0
PI Metabolism R-HSA-1483255 2.567936e-01 0.590 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.129529e-01 0.505 0 0
Diseases of DNA repair R-HSA-9675135 1.903617e-01 0.720 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.517219e-01 0.454 0 0
MHC class II antigen presentation R-HSA-2132295 2.909084e-01 0.536 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 3.954031e-01 0.403 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 3.954031e-01 0.403 0 0
Glucose metabolism R-HSA-70326 2.278698e-01 0.642 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.889252e-01 0.539 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 3.375815e-01 0.472 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 4.312265e-01 0.365 0 0
Signaling by ALK R-HSA-201556 2.747728e-01 0.561 0 0
Selenocysteine synthesis R-HSA-2408557 3.297550e-01 0.482 0 0
NTRK3 as a dependence receptor R-HSA-9603505 3.298215e-01 0.482 0 0
Co-inhibition by BTLA R-HSA-9927353 2.398782e-01 0.620 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 2.167828e-01 0.664 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 4.135286e-01 0.383 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.851801e-01 0.414 0 0
Sodium/Proton exchangers R-HSA-425986 4.312265e-01 0.365 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 4.753660e-01 0.323 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 4.179160e-01 0.379 0 0
Interleukin-7 signaling R-HSA-1266695 2.361957e-01 0.627 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 2.579982e-01 0.588 0 0
SARS-CoV-2 Infection R-HSA-9694516 3.118890e-01 0.506 0 0
Unfolded Protein Response (UPR) R-HSA-381119 2.688820e-01 0.570 0 0
Metal ion SLC transporters R-HSA-425410 4.710699e-01 0.327 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 4.745080e-01 0.324 0 0
Signaling by Leptin R-HSA-2586552 2.517723e-01 0.599 0 0
Specification of primordial germ cells R-HSA-9827857 3.381111e-01 0.471 0 0
Influenza Infection R-HSA-168255 2.082607e-01 0.681 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 4.135286e-01 0.383 0 0
Signal regulatory protein family interactions R-HSA-391160 2.214251e-01 0.655 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 3.851801e-01 0.414 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 4.753660e-01 0.323 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.852236e-01 0.314 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 3.680099e-01 0.434 0 0
SARS-CoV-1 Infection R-HSA-9678108 1.786692e-01 0.748 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 2.889252e-01 0.539 0 0
Interleukin-12 family signaling R-HSA-447115 3.048177e-01 0.516 0 0
Axonal growth stimulation R-HSA-209563 4.867848e-01 0.313 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 4.867848e-01 0.313 0 0
Defective CYP1B1 causes Glaucoma R-HSA-5579000 4.867848e-01 0.313 0 0
Defective ABCA3 causes SMDP3 R-HSA-5683678 4.867848e-01 0.313 0 0
Defective ABCA1 causes TGD R-HSA-5682113 4.867848e-01 0.313 0 0
Defective MAOA causes BRUNS R-HSA-5579012 4.867848e-01 0.313 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 4.867848e-01 0.313 0 0
Defective GCLC causes HAGGSD R-HSA-5578999 4.867848e-01 0.313 0 0
Invadopodia formation R-HSA-8941237 4.867848e-01 0.313 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 4.867848e-01 0.313 0 0
Defective ABCA3 causes SMDP3 R-HSA-5688399 4.867848e-01 0.313 0 0
MET activates PTPN11 R-HSA-8865999 4.867848e-01 0.313 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 4.867848e-01 0.313 0 0
Activation of BMF and translocation to mitochondria R-HSA-139910 4.867848e-01 0.313 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 4.867848e-01 0.313 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 4.867848e-01 0.313 0 0
Histamine receptors R-HSA-390650 4.867848e-01 0.313 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 4.867848e-01 0.313 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 4.867848e-01 0.313 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 4.886856e-01 0.311 0 0
DNA Damage Bypass R-HSA-73893 4.905940e-01 0.309 0 0
Sensory processing of sound R-HSA-9659379 4.927665e-01 0.307 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 4.927665e-01 0.307 0 0
Negative regulation of FLT3 R-HSA-9706369 4.985639e-01 0.302 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 4.985639e-01 0.302 0 0
Signaling by Erythropoietin R-HSA-9006335 4.997240e-01 0.301 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 4.997240e-01 0.301 0 0
Termination of translesion DNA synthesis R-HSA-5656169 4.997240e-01 0.301 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 4.997240e-01 0.301 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.001503e-01 0.301 0 0
Regulation of CDH1 Function R-HSA-9764561 5.003859e-01 0.301 0 0
Epigenetic regulation of gene expression R-HSA-212165 5.055621e-01 0.296 0 0
Adherens junctions interactions R-HSA-418990 5.060541e-01 0.296 0 0
Platelet homeostasis R-HSA-418346 5.075565e-01 0.295 0 0
Assembly of the pre-replicative complex R-HSA-68867 5.079394e-01 0.294 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 5.084221e-01 0.294 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 5.084221e-01 0.294 0 0
PKR-mediated signaling R-HSA-9833482 5.084221e-01 0.294 0 0
Regulation of RAS by GAPs R-HSA-5658442 5.099132e-01 0.293 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 5.102600e-01 0.292 0 0
G1/S-Specific Transcription R-HSA-69205 5.111765e-01 0.291 0 0
PRC2 methylates histones and DNA R-HSA-212300 5.111765e-01 0.291 0 0
HSF1 activation R-HSA-3371511 5.111765e-01 0.291 0 0
RUNX2 regulates bone development R-HSA-8941326 5.111765e-01 0.291 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 5.132510e-01 0.290 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 5.132510e-01 0.290 0 0
Hedgehog 'off' state R-HSA-5610787 5.146866e-01 0.288 0 0
Ca2+ pathway R-HSA-4086398 5.168467e-01 0.287 0 0
Formation of apoptosome R-HSA-111458 5.173567e-01 0.286 0 0
Regulation of the apoptosome activity R-HSA-9627069 5.173567e-01 0.286 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 5.173567e-01 0.286 0 0
MAPK3 (ERK1) activation R-HSA-110056 5.173567e-01 0.286 0 0
2-LTR circle formation R-HSA-164843 5.173567e-01 0.286 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 5.173567e-01 0.286 0 0
Folding of actin by CCT/TriC R-HSA-390450 5.173567e-01 0.286 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 5.173567e-01 0.286 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 5.173567e-01 0.286 0 0
Regulation of CDH11 function R-HSA-9762292 5.173567e-01 0.286 0 0
Arachidonate production from DAG R-HSA-426048 5.173567e-01 0.286 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 5.173567e-01 0.286 0 0
Receptor Mediated Mitophagy R-HSA-8934903 5.173567e-01 0.286 0 0
Pexophagy R-HSA-9664873 5.173567e-01 0.286 0 0
Tandem pore domain potassium channels R-HSA-1296346 5.173567e-01 0.286 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 5.173567e-01 0.286 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 5.173567e-01 0.286 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 5.173567e-01 0.286 0 0
Dual incision in TC-NER R-HSA-6782135 5.184552e-01 0.285 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 5.242843e-01 0.280 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 5.242843e-01 0.280 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 5.309610e-01 0.275 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 5.309610e-01 0.275 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 5.309610e-01 0.275 0 0
Signaling by NOTCH4 R-HSA-9013694 5.329872e-01 0.273 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 5.332865e-01 0.273 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 5.332865e-01 0.273 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 5.405537e-01 0.267 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 5.405537e-01 0.267 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 5.409897e-01 0.267 0 0
Amine ligand-binding receptors R-HSA-375280 5.409897e-01 0.267 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 5.477859e-01 0.261 0 0
EGFR downregulation R-HSA-182971 5.483043e-01 0.261 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 5.483043e-01 0.261 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 5.483043e-01 0.261 0 0
Downstream signal transduction R-HSA-186763 5.483043e-01 0.261 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 5.506538e-01 0.259 0 0
HCN channels R-HSA-1296061 5.508943e-01 0.259 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 5.508943e-01 0.259 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 5.508943e-01 0.259 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 5.508943e-01 0.259 0 0
ATP sensitive Potassium channels R-HSA-1296025 5.508943e-01 0.259 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 5.508943e-01 0.259 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 5.508943e-01 0.259 0 0
TNFR1-mediated ceramide production R-HSA-5626978 5.508943e-01 0.259 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 5.508943e-01 0.259 0 0
Alanine metabolism R-HSA-8964540 5.508943e-01 0.259 0 0
NADE modulates death signalling R-HSA-205025 5.508943e-01 0.259 0 0
Sensory perception of sour taste R-HSA-9729555 5.508943e-01 0.259 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 5.508943e-01 0.259 0 0
Dopamine receptors R-HSA-390651 5.508943e-01 0.259 0 0
Interleukin-38 signaling R-HSA-9007892 5.508943e-01 0.259 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 5.539094e-01 0.257 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 5.544020e-01 0.256 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 5.570467e-01 0.254 0 0
Signaling by APC mutants R-HSA-4839744 5.570467e-01 0.254 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 5.570467e-01 0.254 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 5.570467e-01 0.254 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 5.570467e-01 0.254 0 0
Regulation of gene expression in early pancreatic precursor cells R-HSA-210747 5.570467e-01 0.254 0 0
Inorganic anion exchange by SLC26 transporters R-HSA-427601 5.570467e-01 0.254 0 0
LGI-ADAM interactions R-HSA-5682910 5.570467e-01 0.254 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 5.608877e-01 0.251 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 5.608877e-01 0.251 0 0
Integration of energy metabolism R-HSA-163685 5.662327e-01 0.247 0 0
Smooth Muscle Contraction R-HSA-445355 5.662712e-01 0.247 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 5.670519e-01 0.246 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 5.670519e-01 0.246 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 5.670519e-01 0.246 0 0
Clathrin-mediated endocytosis R-HSA-8856828 5.703935e-01 0.244 0 0
Inwardly rectifying K+ channels R-HSA-1296065 5.717251e-01 0.243 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 5.717251e-01 0.243 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 5.717251e-01 0.243 0 0
Developmental Biology R-HSA-1266738 5.755659e-01 0.240 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 5.758694e-01 0.240 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 5.803882e-01 0.236 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 5.803882e-01 0.236 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 5.882660e-01 0.230 0 0
Mitochondrial protein import R-HSA-1268020 5.882660e-01 0.230 0 0
tRNA processing in the nucleus R-HSA-6784531 5.882660e-01 0.230 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 5.919590e-01 0.228 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 5.920379e-01 0.228 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 5.920379e-01 0.228 0 0
Tie2 Signaling R-HSA-210993 5.920379e-01 0.228 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 5.920379e-01 0.228 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 5.926807e-01 0.227 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 5.926807e-01 0.227 0 0
Formation of the nephric duct R-HSA-9830364 5.926807e-01 0.227 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 5.926807e-01 0.227 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 5.943556e-01 0.226 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 5.943556e-01 0.226 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 5.943556e-01 0.226 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 5.943556e-01 0.226 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 5.943556e-01 0.226 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 5.943556e-01 0.226 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 5.943556e-01 0.226 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 5.943556e-01 0.226 0 0
NF-kB is activated and signals survival R-HSA-209560 5.943556e-01 0.226 0 0
Signaling by AMER1 mutants R-HSA-4839748 5.943556e-01 0.226 0 0
Signaling by AXIN mutants R-HSA-4839735 5.943556e-01 0.226 0 0
G-protein beta:gamma signalling R-HSA-397795 5.944967e-01 0.226 0 0
DNA Replication R-HSA-69306 5.962061e-01 0.225 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 5.968487e-01 0.224 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 5.968487e-01 0.224 0 0
Attenuation phase R-HSA-3371568 5.968487e-01 0.224 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 5.968487e-01 0.224 0 0
Generation of second messenger molecules R-HSA-202433 5.968487e-01 0.224 0 0
Circadian clock R-HSA-9909396 5.972208e-01 0.224 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 5.994590e-01 0.222 0 0
Organelle biogenesis and maintenance R-HSA-1852241 6.009461e-01 0.221 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 6.021909e-01 0.220 0 0
Signaling by NOTCH3 R-HSA-9012852 6.021909e-01 0.220 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 6.049719e-01 0.218 0 0
Trafficking of myristoylated proteins to the cilium R-HSA-5624138 6.069986e-01 0.217 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 6.069986e-01 0.217 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 6.069986e-01 0.217 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 6.069986e-01 0.217 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 6.069986e-01 0.217 0 0
Defective F9 activation R-HSA-9673221 6.069986e-01 0.217 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.069986e-01 0.217 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 6.069986e-01 0.217 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 6.069986e-01 0.217 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 6.069986e-01 0.217 0 0
Activation of AKT2 R-HSA-165158 6.069986e-01 0.217 0 0
NTRK2 activates RAC1 R-HSA-9032759 6.069986e-01 0.217 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 6.069986e-01 0.217 0 0
Muscarinic acetylcholine receptors R-HSA-390648 6.069986e-01 0.217 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 6.069986e-01 0.217 0 0
Toxicity of botulinum toxin type C (botC) R-HSA-5250971 6.069986e-01 0.217 0 0
Hedgehog 'on' state R-HSA-5632684 6.077612e-01 0.216 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 6.169810e-01 0.210 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 6.169810e-01 0.210 0 0
Signaling by EGFR in Cancer R-HSA-1643713 6.173884e-01 0.209 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 6.173884e-01 0.209 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 6.173884e-01 0.209 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 6.173884e-01 0.209 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 6.173884e-01 0.209 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 6.180717e-01 0.209 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 6.195748e-01 0.208 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 6.195748e-01 0.208 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.205734e-01 0.207 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 6.205734e-01 0.207 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.205734e-01 0.207 0 0
Specification of the neural plate border R-HSA-9834899 6.205734e-01 0.207 0 0
The NLRP3 inflammasome R-HSA-844456 6.205734e-01 0.207 0 0
Synthesis of DNA R-HSA-69239 6.212772e-01 0.207 0 0
Gene Silencing by RNA R-HSA-211000 6.212772e-01 0.207 0 0
Pyruvate metabolism R-HSA-70268 6.273775e-01 0.202 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 6.292589e-01 0.201 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 6.292589e-01 0.201 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 6.292589e-01 0.201 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 6.292589e-01 0.201 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 6.292589e-01 0.201 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 6.292589e-01 0.201 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 6.292589e-01 0.201 0 0
VLDLR internalisation and degradation R-HSA-8866427 6.292589e-01 0.201 0 0
Leading Strand Synthesis R-HSA-69109 6.292589e-01 0.201 0 0
Polymerase switching R-HSA-69091 6.292589e-01 0.201 0 0
Regulation of IFNG signaling R-HSA-877312 6.292589e-01 0.201 0 0
Metabolism of RNA R-HSA-8953854 6.336739e-01 0.198 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 6.338174e-01 0.198 0 0
Stimuli-sensing channels R-HSA-2672351 6.338174e-01 0.198 0 0
Gap junction trafficking and regulation R-HSA-157858 6.362019e-01 0.196 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 6.365333e-01 0.196 0 0
Intra-Golgi traffic R-HSA-6811438 6.365333e-01 0.196 0 0
Cellular response to hypoxia R-HSA-1234174 6.373369e-01 0.196 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 6.379323e-01 0.195 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 6.379323e-01 0.195 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.384345e-01 0.195 0 0
Packaging Of Telomere Ends R-HSA-171306 6.411360e-01 0.193 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 6.411360e-01 0.193 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 6.411360e-01 0.193 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 6.411360e-01 0.193 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.429419e-01 0.192 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 6.477163e-01 0.189 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 6.477163e-01 0.189 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 6.477163e-01 0.189 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 6.530855e-01 0.185 0 0
PI3K Cascade R-HSA-109704 6.538287e-01 0.185 0 0
Plus-strand DNA synthesis R-HSA-164525 6.560970e-01 0.183 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 6.560970e-01 0.183 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 6.560970e-01 0.183 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 6.560970e-01 0.183 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 6.560970e-01 0.183 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 6.560970e-01 0.183 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 6.560970e-01 0.183 0 0
NGF-independant TRKA activation R-HSA-187024 6.560970e-01 0.183 0 0
Pentose phosphate pathway disease R-HSA-6791465 6.560970e-01 0.183 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 6.560970e-01 0.183 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 6.560970e-01 0.183 0 0
Formation of the Editosome R-HSA-75094 6.560970e-01 0.183 0 0
Phosphorylation of Emi1 R-HSA-176417 6.560970e-01 0.183 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 6.560970e-01 0.183 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 6.560970e-01 0.183 0 0
TCR signaling R-HSA-202403 6.582634e-01 0.182 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 6.585356e-01 0.181 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 6.585356e-01 0.181 0 0
PERK regulates gene expression R-HSA-381042 6.585356e-01 0.181 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 6.617754e-01 0.179 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 6.617754e-01 0.179 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 6.617754e-01 0.179 0 0
FGFR1c ligand binding and activation R-HSA-190373 6.617754e-01 0.179 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 6.617754e-01 0.179 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 6.617754e-01 0.179 0 0
Maturation of nucleoprotein R-HSA-9683610 6.617754e-01 0.179 0 0
Interleukin-6 signaling R-HSA-1059683 6.617754e-01 0.179 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 6.638959e-01 0.178 0 0
Cilium Assembly R-HSA-5617833 6.658612e-01 0.177 0 0
Protein ubiquitination R-HSA-8852135 6.677693e-01 0.175 0 0
Base Excision Repair R-HSA-73884 6.680458e-01 0.175 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 6.692922e-01 0.174 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.709349e-01 0.173 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.734485e-01 0.172 0 0
Signalling to RAS R-HSA-167044 6.734485e-01 0.172 0 0
ERK/MAPK targets R-HSA-198753 6.734485e-01 0.172 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.734485e-01 0.172 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 6.734485e-01 0.172 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.734485e-01 0.172 0 0
Signaling by Hedgehog R-HSA-5358351 6.745444e-01 0.171 0 0
Triglyceride catabolism R-HSA-163560 6.783672e-01 0.169 0 0
FLT3 signaling in disease R-HSA-9682385 6.783672e-01 0.169 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 6.812769e-01 0.167 0 0
Transcription of the HIV genome R-HSA-167172 6.830277e-01 0.166 0 0
RAB geranylgeranylation R-HSA-8873719 6.848124e-01 0.164 0 0
Co-inhibition by PD-1 R-HSA-389948 6.852853e-01 0.164 0 0
DNA methylation R-HSA-5334118 6.856507e-01 0.164 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 6.856507e-01 0.164 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 6.856507e-01 0.164 0 0
Orc1 removal from chromatin R-HSA-68949 6.875067e-01 0.163 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 6.875067e-01 0.163 0 0
mRNA 3'-end processing R-HSA-72187 6.875067e-01 0.163 0 0
DAP12 interactions R-HSA-2172127 6.914956e-01 0.160 0 0
Retrograde neurotrophin signalling R-HSA-177504 6.919565e-01 0.160 0 0
HDL assembly R-HSA-8963896 6.919565e-01 0.160 0 0
Hydrolysis of LPC R-HSA-1483115 6.919565e-01 0.160 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 6.919565e-01 0.160 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 6.919565e-01 0.160 0 0
Acyl chain remodeling of CL R-HSA-1482798 6.919565e-01 0.160 0 0
Malate-aspartate shuttle R-HSA-9856872 6.919565e-01 0.160 0 0
Regulation of insulin secretion R-HSA-422356 6.932912e-01 0.159 0 0
Degradation of DVL R-HSA-4641258 6.974137e-01 0.157 0 0
Cleavage of the damaged purine R-HSA-110331 6.974137e-01 0.157 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.977679e-01 0.156 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 6.977679e-01 0.156 0 0
Attachment and Entry R-HSA-9694614 6.977679e-01 0.156 0 0
Glutathione synthesis and recycling R-HSA-174403 6.977679e-01 0.156 0 0
Assembly Of The HIV Virion R-HSA-175474 6.977679e-01 0.156 0 0
rRNA processing R-HSA-72312 6.989474e-01 0.156 0 0
STAT5 Activation R-HSA-9645135 6.990639e-01 0.155 0 0
Erythropoietin activates STAT5 R-HSA-9027283 6.990639e-01 0.155 0 0
Uncoating of the HIV Virion R-HSA-162585 6.990639e-01 0.155 0 0
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors R-HSA-629587 6.990639e-01 0.155 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 6.990639e-01 0.155 0 0
Hydrolysis of LPE R-HSA-1483152 6.990639e-01 0.155 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 6.990639e-01 0.155 0 0
Neurofascin interactions R-HSA-447043 6.990639e-01 0.155 0 0
Metabolism of vitamin K R-HSA-6806664 6.990639e-01 0.155 0 0
NADPH regeneration R-HSA-389542 6.990639e-01 0.155 0 0
Leukotriene receptors R-HSA-391906 6.990639e-01 0.155 0 0
VLDL assembly R-HSA-8866423 6.990639e-01 0.155 0 0
Lipid particle organization R-HSA-8964572 6.990639e-01 0.155 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 6.999763e-01 0.155 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.035334e-01 0.153 0 0
Regulation of PTEN stability and activity R-HSA-8948751 7.035334e-01 0.153 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 7.146625e-01 0.146 0 0
Depurination R-HSA-73927 7.156672e-01 0.145 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 7.190075e-01 0.143 0 0
Erythropoietin activates RAS R-HSA-9027284 7.198782e-01 0.143 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 7.198782e-01 0.143 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 7.198782e-01 0.143 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.198782e-01 0.143 0 0
Telomere C-strand synthesis initiation R-HSA-174430 7.198782e-01 0.143 0 0
p38MAPK events R-HSA-171007 7.198782e-01 0.143 0 0
Biotin transport and metabolism R-HSA-196780 7.198782e-01 0.143 0 0
Other semaphorin interactions R-HSA-416700 7.198782e-01 0.143 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 7.206866e-01 0.142 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 7.206866e-01 0.142 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 7.206866e-01 0.142 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.206866e-01 0.142 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 7.206866e-01 0.142 0 0
LDL clearance R-HSA-8964038 7.206866e-01 0.142 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 7.208873e-01 0.142 0 0
Regulation of pyruvate metabolism R-HSA-9861718 7.249242e-01 0.140 0 0
Mitochondrial protein degradation R-HSA-9837999 7.298812e-01 0.137 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 7.331254e-01 0.135 0 0
Stabilization of p53 R-HSA-69541 7.331254e-01 0.135 0 0
Pentose phosphate pathway R-HSA-71336 7.331254e-01 0.135 0 0
HDACs deacetylate histones R-HSA-3214815 7.339241e-01 0.134 0 0
Signaling by FGFR2 R-HSA-5654738 7.347082e-01 0.134 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 7.366647e-01 0.133 0 0
IFNG signaling activates MAPKs R-HSA-9732724 7.366647e-01 0.133 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 7.366647e-01 0.133 0 0
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis R-HSA-9632974 7.366647e-01 0.133 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 7.366647e-01 0.133 0 0
mRNA Editing: C to U Conversion R-HSA-72200 7.366647e-01 0.133 0 0
Ca2+ activated K+ channels R-HSA-1296052 7.366647e-01 0.133 0 0
LDL remodeling R-HSA-8964041 7.366647e-01 0.133 0 0
VLDL clearance R-HSA-8964046 7.366647e-01 0.133 0 0
Activation of TRKA receptors R-HSA-187015 7.366647e-01 0.133 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 7.366647e-01 0.133 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 7.366647e-01 0.133 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 7.366647e-01 0.133 0 0
Maturation of replicase proteins R-HSA-9694301 7.366647e-01 0.133 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 7.381620e-01 0.132 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 7.381620e-01 0.132 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 7.406555e-01 0.130 0 0
Interleukin receptor SHC signaling R-HSA-912526 7.422279e-01 0.129 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 7.422279e-01 0.129 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 7.422279e-01 0.129 0 0
Growth hormone receptor signaling R-HSA-982772 7.422279e-01 0.129 0 0
Insulin receptor signalling cascade R-HSA-74751 7.425814e-01 0.129 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 7.436334e-01 0.129 0 0
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-HSA-2142816 7.456339e-01 0.127 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 7.456339e-01 0.127 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 7.456339e-01 0.127 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 7.456339e-01 0.127 0 0
Phase 4 - resting membrane potential R-HSA-5576886 7.456339e-01 0.127 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 7.456339e-01 0.127 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 7.497905e-01 0.125 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 7.497905e-01 0.125 0 0
HIV Transcription Elongation R-HSA-167169 7.497905e-01 0.125 0 0
Interleukin-2 family signaling R-HSA-451927 7.497905e-01 0.125 0 0
IRS-mediated signalling R-HSA-112399 7.620791e-01 0.118 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 7.624246e-01 0.118 0 0
Complex III assembly R-HSA-9865881 7.624246e-01 0.118 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 7.624246e-01 0.118 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.624246e-01 0.118 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 7.624246e-01 0.118 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 7.625714e-01 0.118 0 0
FGFR1 mutant receptor activation R-HSA-1839124 7.625714e-01 0.118 0 0
Cardiogenesis R-HSA-9733709 7.625714e-01 0.118 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 7.625714e-01 0.118 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 7.631700e-01 0.117 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 7.656690e-01 0.116 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 7.656690e-01 0.116 0 0
Phase 2 - plateau phase R-HSA-5576893 7.693288e-01 0.114 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 7.693288e-01 0.114 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 7.693288e-01 0.114 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 7.693288e-01 0.114 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 7.693288e-01 0.114 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 7.693288e-01 0.114 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 7.693288e-01 0.114 0 0
Formation of xylulose-5-phosphate R-HSA-5661270 7.693288e-01 0.114 0 0
Disorders of Developmental Biology R-HSA-9675151 7.693288e-01 0.114 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 7.693288e-01 0.114 0 0
Passive transport by Aquaporins R-HSA-432047 7.693288e-01 0.114 0 0
tRNA modification in the mitochondrion R-HSA-6787450 7.693288e-01 0.114 0 0
Reverse Transcription of HIV RNA R-HSA-162589 7.695694e-01 0.114 0 0
Minus-strand DNA synthesis R-HSA-164516 7.695694e-01 0.114 0 0
ALKBH3 mediated reversal of alkylation damage R-HSA-112126 7.695694e-01 0.114 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 7.695694e-01 0.114 0 0
phospho-PLA2 pathway R-HSA-111995 7.695694e-01 0.114 0 0
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 R-HSA-211957 7.695694e-01 0.114 0 0
Highly calcium permeable nicotinic acetylcholine receptors R-HSA-629597 7.695694e-01 0.114 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 7.695694e-01 0.114 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 7.695694e-01 0.114 0 0
Interleukin-9 signaling R-HSA-8985947 7.695694e-01 0.114 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 7.695694e-01 0.114 0 0
Fructose biosynthesis R-HSA-5652227 7.695694e-01 0.114 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 7.695694e-01 0.114 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 7.695694e-01 0.114 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 7.695694e-01 0.114 0 0
Alpha-defensins R-HSA-1462054 7.695694e-01 0.114 0 0
Interleukin-23 signaling R-HSA-9020933 7.695694e-01 0.114 0 0
Degradation of CDH1 R-HSA-9766229 7.701557e-01 0.113 0 0
Activation of HOX genes during differentiation R-HSA-5619507 7.706834e-01 0.113 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 7.706834e-01 0.113 0 0
RSV-host interactions R-HSA-9833110 7.706834e-01 0.113 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 7.793261e-01 0.108 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 7.793261e-01 0.108 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 7.793261e-01 0.108 0 0
Miscellaneous transport and binding events R-HSA-5223345 7.793261e-01 0.108 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 7.807711e-01 0.107 0 0
Signaling by FGFR1 in disease R-HSA-5655302 7.807711e-01 0.107 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.813169e-01 0.107 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 7.813169e-01 0.107 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.813169e-01 0.107 0 0
G protein gated Potassium channels R-HSA-1296059 7.813169e-01 0.107 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.813169e-01 0.107 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.813169e-01 0.107 0 0
Metabolism of non-coding RNA R-HSA-194441 7.880096e-01 0.103 0 0
snRNP Assembly R-HSA-191859 7.880096e-01 0.103 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 7.880096e-01 0.103 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 7.910758e-01 0.102 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 7.910758e-01 0.102 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 7.910758e-01 0.102 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 7.910758e-01 0.102 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 7.910758e-01 0.102 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 7.910758e-01 0.102 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 7.924731e-01 0.101 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 7.951103e-01 0.100 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 7.951103e-01 0.100 0 0
Depyrimidination R-HSA-73928 7.951103e-01 0.100 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 7.951295e-01 0.100 0 0
Signal amplification R-HSA-392518 7.951295e-01 0.100 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 7.975087e-01 0.098 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 7.983642e-01 0.098 0 0
p75NTR regulates axonogenesis R-HSA-193697 7.983642e-01 0.098 0 0
Enzymatic degradation of Dopamine by monoamine oxidase R-HSA-379398 7.983642e-01 0.098 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 7.983642e-01 0.098 0 0
Regulation of signaling by NODAL R-HSA-1433617 7.983642e-01 0.098 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 7.983642e-01 0.098 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 7.983642e-01 0.098 0 0
Regulated proteolysis of p75NTR R-HSA-193692 7.983642e-01 0.098 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 7.983642e-01 0.098 0 0
Cellular response to mitochondrial stress R-HSA-9840373 7.983642e-01 0.098 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 7.989510e-01 0.097 0 0
GABA receptor activation R-HSA-977443 8.001531e-01 0.097 0 0
Defective pyroptosis R-HSA-9710421 8.087027e-01 0.092 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 8.095950e-01 0.092 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 8.097828e-01 0.092 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 8.109915e-01 0.091 0 0
FGFR1 ligand binding and activation R-HSA-190242 8.109915e-01 0.091 0 0
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670 8.109915e-01 0.091 0 0
Transport of connexons to the plasma membrane R-HSA-190872 8.109915e-01 0.091 0 0
Nephron development R-HSA-9831926 8.109915e-01 0.091 0 0
Aquaporin-mediated transport R-HSA-445717 8.117591e-01 0.091 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 8.117591e-01 0.091 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 8.117591e-01 0.091 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 8.153773e-01 0.089 0 0
Insulin processing R-HSA-264876 8.153773e-01 0.089 0 0
Collagen formation R-HSA-1474290 8.165882e-01 0.088 0 0
Regulation of endogenous retroelements R-HSA-9842860 8.209859e-01 0.086 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 8.214998e-01 0.085 0 0
Gap junction trafficking R-HSA-190828 8.215669e-01 0.085 0 0
Binding and entry of HIV virion R-HSA-173107 8.235623e-01 0.084 0 0
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors R-HSA-629594 8.235623e-01 0.084 0 0
DNA replication initiation R-HSA-68952 8.235623e-01 0.084 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 8.235623e-01 0.084 0 0
Metabolism of serotonin R-HSA-380612 8.235623e-01 0.084 0 0
Formation of intermediate mesoderm R-HSA-9761174 8.235623e-01 0.084 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 8.235623e-01 0.084 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 8.235623e-01 0.084 0 0
Enzymatic degradation of dopamine by COMT R-HSA-379397 8.235623e-01 0.084 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 8.235623e-01 0.084 0 0
Serotonin receptors R-HSA-390666 8.235623e-01 0.084 0 0
Josephin domain DUBs R-HSA-5689877 8.235623e-01 0.084 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 8.239917e-01 0.084 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 8.239917e-01 0.084 0 0
RNA Polymerase III Transcription R-HSA-74158 8.239917e-01 0.084 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 8.239917e-01 0.084 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.250457e-01 0.084 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 8.291940e-01 0.081 0 0
Regulation of signaling by CBL R-HSA-912631 8.291940e-01 0.081 0 0
Translesion Synthesis by POLH R-HSA-110320 8.291940e-01 0.081 0 0
Other interleukin signaling R-HSA-449836 8.291940e-01 0.081 0 0
Crosslinking of collagen fibrils R-HSA-2243919 8.291940e-01 0.081 0 0
Maturation of nucleoprotein R-HSA-9694631 8.291940e-01 0.081 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 8.291940e-01 0.081 0 0
PPARA activates gene expression R-HSA-1989781 8.305869e-01 0.081 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 8.306495e-01 0.081 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 8.306495e-01 0.081 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 8.306495e-01 0.081 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 8.306495e-01 0.081 0 0
Inflammasomes R-HSA-622312 8.306495e-01 0.081 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 8.328065e-01 0.079 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 8.328065e-01 0.079 0 0
G alpha (s) signalling events R-HSA-418555 8.333057e-01 0.079 0 0
Nucleosome assembly R-HSA-774815 8.337235e-01 0.079 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.337235e-01 0.079 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 8.337235e-01 0.079 0 0
Fanconi Anemia Pathway R-HSA-6783310 8.337235e-01 0.079 0 0
Degradation of AXIN R-HSA-4641257 8.371121e-01 0.077 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 8.371121e-01 0.077 0 0
Collagen chain trimerization R-HSA-8948216 8.371121e-01 0.077 0 0
Ion transport by P-type ATPases R-HSA-936837 8.434533e-01 0.074 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.438341e-01 0.074 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.451947e-01 0.073 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 8.456126e-01 0.073 0 0
FGFR2b ligand binding and activation R-HSA-190377 8.456126e-01 0.073 0 0
FGFRL1 modulation of FGFR1 signaling R-HSA-5658623 8.456126e-01 0.073 0 0
vRNA Synthesis R-HSA-192814 8.456126e-01 0.073 0 0
vRNP Assembly R-HSA-192905 8.456126e-01 0.073 0 0
Chylomicron assembly R-HSA-8963888 8.456126e-01 0.073 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 8.456126e-01 0.073 0 0
Bicarbonate transporters R-HSA-425381 8.456126e-01 0.073 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 8.456126e-01 0.073 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 8.456126e-01 0.073 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 8.456126e-01 0.073 0 0
Transport of RCbl within the body R-HSA-9758890 8.456126e-01 0.073 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 8.458003e-01 0.073 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 8.458003e-01 0.073 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 8.458003e-01 0.073 0 0
Signaling by NODAL R-HSA-1181150 8.458003e-01 0.073 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 8.458003e-01 0.073 0 0
Acyl chain remodelling of PI R-HSA-1482922 8.458003e-01 0.073 0 0
Pregnenolone biosynthesis R-HSA-196108 8.458003e-01 0.073 0 0
Downstream TCR signaling R-HSA-202424 8.481544e-01 0.072 0 0
Neurotransmitter release cycle R-HSA-112310 8.481544e-01 0.072 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.494029e-01 0.071 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.494029e-01 0.071 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.545787e-01 0.068 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 8.579552e-01 0.067 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 8.579552e-01 0.067 0 0
Neurotransmitter clearance R-HSA-112311 8.579552e-01 0.067 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 8.579552e-01 0.067 0 0
Signaling by FGFR R-HSA-190236 8.582580e-01 0.066 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 8.609251e-01 0.065 0 0
Basigin interactions R-HSA-210991 8.609251e-01 0.065 0 0
Presynaptic nicotinic acetylcholine receptors R-HSA-622323 8.649084e-01 0.063 0 0
Negative regulation of TCF-dependent signaling by WNT ligand antagonists R-HSA-3772470 8.649084e-01 0.063 0 0
Plasmalogen biosynthesis R-HSA-75896 8.649084e-01 0.063 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 8.649084e-01 0.063 0 0
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB R-HSA-141333 8.649084e-01 0.063 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 8.649084e-01 0.063 0 0
Gluconeogenesis R-HSA-70263 8.661754e-01 0.062 0 0
Adaptive Immune System R-HSA-1280218 8.678269e-01 0.062 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 8.696619e-01 0.061 0 0
UCH proteinases R-HSA-5689603 8.702101e-01 0.060 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 8.716364e-01 0.060 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 8.716364e-01 0.060 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 8.716364e-01 0.060 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 8.716364e-01 0.060 0 0
Glycogen metabolism R-HSA-8982491 8.716364e-01 0.060 0 0
Signaling by PDGFR in disease R-HSA-9671555 8.746791e-01 0.058 0 0
Interferon alpha/beta signaling R-HSA-909733 8.760977e-01 0.057 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 8.809553e-01 0.055 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 8.816509e-01 0.055 0 0
Scavenging by Class F Receptors R-HSA-3000484 8.817934e-01 0.055 0 0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA R-HSA-77305 8.817934e-01 0.055 0 0
Beta oxidation of myristoyl-CoA to lauroyl-CoA R-HSA-77285 8.817934e-01 0.055 0 0
GRB2 events in EGFR signaling R-HSA-179812 8.817934e-01 0.055 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 8.817934e-01 0.055 0 0
MET activates RAS signaling R-HSA-8851805 8.817934e-01 0.055 0 0
Interleukin-15 signaling R-HSA-8983432 8.817934e-01 0.055 0 0
Synthesis of GDP-mannose R-HSA-446205 8.817934e-01 0.055 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 8.817934e-01 0.055 0 0
Disorders of Nervous System Development R-HSA-9697154 8.817934e-01 0.055 0 0
Pervasive developmental disorders R-HSA-9005895 8.817934e-01 0.055 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 8.817934e-01 0.055 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 8.817934e-01 0.055 0 0
Estrogen biosynthesis R-HSA-193144 8.817934e-01 0.055 0 0
ER to Golgi Anterograde Transport R-HSA-199977 8.845804e-01 0.053 0 0
RNA Polymerase I Transcription R-HSA-73864 8.853878e-01 0.053 0 0
SARS-CoV Infections R-HSA-9679506 8.867769e-01 0.052 0 0
Ion channel transport R-HSA-983712 8.868247e-01 0.052 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 8.871687e-01 0.052 0 0
FGFR2 alternative splicing R-HSA-6803529 8.871687e-01 0.052 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 8.871687e-01 0.052 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 8.871687e-01 0.052 0 0
Fructose metabolism R-HSA-5652084 8.871687e-01 0.052 0 0
Signaling by KIT in disease R-HSA-9669938 8.871687e-01 0.052 0 0
Cellular hexose transport R-HSA-189200 8.871687e-01 0.052 0 0
HIV Transcription Initiation R-HSA-167161 8.909788e-01 0.050 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.909788e-01 0.050 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.909788e-01 0.050 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.930434e-01 0.049 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 8.931175e-01 0.049 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 8.939430e-01 0.049 0 0
Acetylcholine binding and downstream events R-HSA-181431 8.965689e-01 0.047 0 0
Postsynaptic nicotinic acetylcholine receptors R-HSA-622327 8.965689e-01 0.047 0 0
Adenylate cyclase activating pathway R-HSA-170660 8.965689e-01 0.047 0 0
FGFR2c ligand binding and activation R-HSA-190375 8.965689e-01 0.047 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 8.965689e-01 0.047 0 0
FGFR4 ligand binding and activation R-HSA-190322 8.965689e-01 0.047 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 8.965689e-01 0.047 0 0
Mtb iron assimilation by chelation R-HSA-1222449 8.965689e-01 0.047 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 8.965689e-01 0.047 0 0
Formation of axial mesoderm R-HSA-9796292 8.965689e-01 0.047 0 0
FGFR3 mutant receptor activation R-HSA-2033514 8.965689e-01 0.047 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 8.965689e-01 0.047 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 8.965689e-01 0.047 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.965689e-01 0.047 0 0
Formation of paraxial mesoderm R-HSA-9793380 8.966472e-01 0.047 0 0
Viral Messenger RNA Synthesis R-HSA-168325 8.966472e-01 0.047 0 0
Termination of O-glycan biosynthesis R-HSA-977068 8.984951e-01 0.046 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 8.984951e-01 0.046 0 0
Biosynthesis of maresins R-HSA-9018682 8.984951e-01 0.046 0 0
Synthesis of UDP-N-acetyl-glucosamine R-HSA-446210 8.984951e-01 0.046 0 0
Mitochondrial mRNA modification R-HSA-9937008 8.984951e-01 0.046 0 0
Activation of GABAB receptors R-HSA-991365 8.996559e-01 0.046 0 0
GABA B receptor activation R-HSA-977444 8.996559e-01 0.046 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 9.009931e-01 0.045 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.012020e-01 0.045 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.012020e-01 0.045 0 0
Interferon gamma signaling R-HSA-877300 9.014008e-01 0.045 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.038064e-01 0.044 0 0
Signaling by PDGF R-HSA-186797 9.038064e-01 0.044 0 0
ER-Phagosome pathway R-HSA-1236974 9.041920e-01 0.044 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 9.077178e-01 0.042 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 9.077178e-01 0.042 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.083590e-01 0.042 0 0
Interleukin-6 family signaling R-HSA-6783589 9.087537e-01 0.042 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 9.094983e-01 0.041 0 0
FGFR3c ligand binding and activation R-HSA-190372 9.094983e-01 0.041 0 0
Signaling by FGFR4 in disease R-HSA-5655291 9.094983e-01 0.041 0 0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA R-HSA-77348 9.094983e-01 0.041 0 0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA R-HSA-77310 9.094983e-01 0.041 0 0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA R-HSA-77350 9.094983e-01 0.041 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 9.094983e-01 0.041 0 0
Vitamin B2 (riboflavin) metabolism R-HSA-196843 9.094983e-01 0.041 0 0
Biosynthesis of protectins R-HSA-9018681 9.094983e-01 0.041 0 0
Physiological factors R-HSA-5578768 9.094983e-01 0.041 0 0
Prolactin receptor signaling R-HSA-1170546 9.094983e-01 0.041 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 9.094983e-01 0.041 0 0
Non-canonical inflammasome activation R-HSA-9686114 9.094983e-01 0.041 0 0
Zinc transporters R-HSA-435354 9.094983e-01 0.041 0 0
P2Y receptors R-HSA-417957 9.094983e-01 0.041 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 9.094983e-01 0.041 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.099696e-01 0.041 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.099696e-01 0.041 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.099696e-01 0.041 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.099696e-01 0.041 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.103050e-01 0.041 0 0
Protein localization R-HSA-9609507 9.131925e-01 0.039 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.180247e-01 0.037 0 0
Beta-oxidation of pristanoyl-CoA R-HSA-389887 9.180346e-01 0.037 0 0
Laminin interactions R-HSA-3000157 9.180346e-01 0.037 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.180346e-01 0.037 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 9.208120e-01 0.036 0 0
G beta:gamma signalling through BTK R-HSA-8964315 9.208120e-01 0.036 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 9.208120e-01 0.036 0 0
Translesion synthesis by REV1 R-HSA-110312 9.208120e-01 0.036 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 9.208120e-01 0.036 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 9.208120e-01 0.036 0 0
FGFR3 ligand binding and activation R-HSA-190239 9.208120e-01 0.036 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 9.208120e-01 0.036 0 0
Signaling by Activin R-HSA-1502540 9.208120e-01 0.036 0 0
Events associated with phagocytolytic activity of PMN cells R-HSA-8941413 9.208120e-01 0.036 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 9.208120e-01 0.036 0 0
G alpha (z) signalling events R-HSA-418597 9.216631e-01 0.035 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.221339e-01 0.035 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 9.221339e-01 0.035 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.221339e-01 0.035 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 9.221339e-01 0.035 0 0
Selenoamino acid metabolism R-HSA-2408522 9.222613e-01 0.035 0 0
Adipogenesis R-HSA-9843745 9.234423e-01 0.035 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.236028e-01 0.035 0 0
MET activates PTK2 signaling R-HSA-8874081 9.264218e-01 0.033 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.264218e-01 0.033 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.276507e-01 0.033 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 9.285549e-01 0.032 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.285549e-01 0.032 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.285549e-01 0.032 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.285549e-01 0.032 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 9.299298e-01 0.032 0 0
Translesion synthesis by POLI R-HSA-5656121 9.307120e-01 0.031 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 9.307120e-01 0.031 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 9.307120e-01 0.031 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 9.307120e-01 0.031 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 9.307120e-01 0.031 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 9.307120e-01 0.031 0 0
Fructose catabolism R-HSA-70350 9.307120e-01 0.031 0 0
Attachment and Entry R-HSA-9678110 9.307120e-01 0.031 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.321923e-01 0.030 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.321923e-01 0.030 0 0
Synthesis of PA R-HSA-1483166 9.332274e-01 0.030 0 0
Kidney development R-HSA-9830369 9.335184e-01 0.030 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 9.339936e-01 0.030 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.339936e-01 0.030 0 0
Cristae formation R-HSA-8949613 9.339936e-01 0.030 0 0
Signaling by BMP R-HSA-201451 9.339936e-01 0.030 0 0
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane R-HSA-83936 9.339936e-01 0.030 0 0
Phospholipid metabolism R-HSA-1483257 9.354490e-01 0.029 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.383770e-01 0.028 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.383966e-01 0.028 0 0
ABC transporter disorders R-HSA-5619084 9.392835e-01 0.027 0 0
Translesion synthesis by POLK R-HSA-5655862 9.393748e-01 0.027 0 0
Heme assimilation R-HSA-9927020 9.393748e-01 0.027 0 0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids R-HSA-77288 9.393748e-01 0.027 0 0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA R-HSA-77346 9.393748e-01 0.027 0 0
Synthesis of PG R-HSA-1483148 9.393748e-01 0.027 0 0
Galactose catabolism R-HSA-70370 9.393748e-01 0.027 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 9.393748e-01 0.027 0 0
Inositol phosphate metabolism R-HSA-1483249 9.399546e-01 0.027 0 0
Developmental Cell Lineages R-HSA-9734767 9.405330e-01 0.027 0 0
Chaperonin-mediated protein folding R-HSA-390466 9.407810e-01 0.027 0 0
Triglyceride metabolism R-HSA-8979227 9.432397e-01 0.025 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.435326e-01 0.025 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.440718e-01 0.025 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 9.440718e-01 0.025 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 9.440718e-01 0.025 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.440718e-01 0.025 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.440718e-01 0.025 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 9.469550e-01 0.024 0 0
Sulfide oxidation to sulfate R-HSA-1614517 9.469550e-01 0.024 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 9.469550e-01 0.024 0 0
Thyroxine biosynthesis R-HSA-209968 9.469768e-01 0.024 0 0
Glucagon-type ligand receptors R-HSA-420092 9.469768e-01 0.024 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 9.469768e-01 0.024 0 0
Glutathione conjugation R-HSA-156590 9.477195e-01 0.023 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.477195e-01 0.023 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.477195e-01 0.023 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.492581e-01 0.023 0 0
Amyloid fiber formation R-HSA-977225 9.512457e-01 0.022 0 0
Collagen degradation R-HSA-1442490 9.518763e-01 0.021 0 0
Immune System R-HSA-168256 9.522850e-01 0.021 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 9.525174e-01 0.021 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.525174e-01 0.021 0 0
Activated point mutants of FGFR2 R-HSA-2033519 9.535878e-01 0.021 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 9.535878e-01 0.021 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.535878e-01 0.021 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 9.535878e-01 0.021 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 9.535878e-01 0.021 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.539932e-01 0.020 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.539932e-01 0.020 0 0
Maturation of spike protein R-HSA-9694548 9.539932e-01 0.020 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.540232e-01 0.020 0 0
The phototransduction cascade R-HSA-2514856 9.540232e-01 0.020 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.575019e-01 0.019 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.575019e-01 0.019 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.579855e-01 0.019 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.580016e-01 0.019 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.583123e-01 0.018 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.583123e-01 0.018 0 0
ABC-family proteins mediated transport R-HSA-382556 9.591140e-01 0.018 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 9.593915e-01 0.018 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 9.593915e-01 0.018 0 0
Pyrimidine biosynthesis R-HSA-500753 9.593915e-01 0.018 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.593915e-01 0.018 0 0
Amine Oxidase reactions R-HSA-140179 9.593915e-01 0.018 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.593915e-01 0.018 0 0
Diseases of hemostasis R-HSA-9671793 9.593915e-01 0.018 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 9.593915e-01 0.018 0 0
G alpha (q) signalling events R-HSA-416476 9.608686e-01 0.017 0 0
Protein folding R-HSA-391251 9.612536e-01 0.017 0 0
Signaling by Insulin receptor R-HSA-74752 9.612536e-01 0.017 0 0
Nucleotide biosynthesis R-HSA-8956320 9.616299e-01 0.017 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 9.619827e-01 0.017 0 0
HS-GAG degradation R-HSA-2024096 9.619827e-01 0.017 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 9.622488e-01 0.017 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.639658e-01 0.016 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.643885e-01 0.016 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.644699e-01 0.016 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 9.644699e-01 0.016 0 0
Negative regulation of MET activity R-HSA-6807004 9.644699e-01 0.016 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 9.644699e-01 0.016 0 0
Creatine metabolism R-HSA-71288 9.644699e-01 0.016 0 0
Formation of definitive endoderm R-HSA-9823730 9.644699e-01 0.016 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.644699e-01 0.016 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 9.644699e-01 0.016 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.649295e-01 0.016 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.658335e-01 0.015 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.665596e-01 0.015 0 0
G-protein activation R-HSA-202040 9.689133e-01 0.014 0 0
FGFR2 ligand binding and activation R-HSA-190241 9.689133e-01 0.014 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.689133e-01 0.014 0 0
Phenylalanine metabolism R-HSA-8964208 9.689133e-01 0.014 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.689133e-01 0.014 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 9.689133e-01 0.014 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.689133e-01 0.014 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 9.689133e-01 0.014 0 0
Proteasome assembly R-HSA-9907900 9.690952e-01 0.014 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 9.696209e-01 0.013 0 0
Vpu mediated degradation of CD4 R-HSA-180534 9.696209e-01 0.013 0 0
Heme degradation R-HSA-189483 9.696209e-01 0.013 0 0
GPCR downstream signalling R-HSA-388396 9.704101e-01 0.013 0 0
Somitogenesis R-HSA-9824272 9.720608e-01 0.012 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.720608e-01 0.012 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.720608e-01 0.012 0 0
Integrin cell surface interactions R-HSA-216083 9.720866e-01 0.012 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 9.728013e-01 0.012 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 9.728013e-01 0.012 0 0
Serine metabolism R-HSA-977347 9.728013e-01 0.012 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.728624e-01 0.012 0 0
eNOS activation R-HSA-203615 9.728624e-01 0.012 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 9.728624e-01 0.012 0 0
Gap junction assembly R-HSA-190861 9.728624e-01 0.012 0 0
HCMV Late Events R-HSA-9610379 9.739125e-01 0.011 0 0
Parasite infection R-HSA-9664407 9.752913e-01 0.011 0 0
Leishmania phagocytosis R-HSA-9664417 9.752913e-01 0.011 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 9.752913e-01 0.011 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.757684e-01 0.011 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.757684e-01 0.011 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.757684e-01 0.011 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.757684e-01 0.011 0 0
Regulation of Apoptosis R-HSA-169911 9.757684e-01 0.011 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 9.762033e-01 0.010 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 9.762033e-01 0.010 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 9.762033e-01 0.010 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 9.762033e-01 0.010 0 0
Neddylation R-HSA-8951664 9.762427e-01 0.010 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.769296e-01 0.010 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.772016e-01 0.010 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.772016e-01 0.010 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.777639e-01 0.010 0 0
Peroxisomal protein import R-HSA-9033241 9.780050e-01 0.010 0 0
HS-GAG biosynthesis R-HSA-2022928 9.783723e-01 0.009 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.783723e-01 0.009 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 9.791799e-01 0.009 0 0
Carnitine shuttle R-HSA-200425 9.791799e-01 0.009 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 9.791799e-01 0.009 0 0
Interleukin-20 family signaling R-HSA-8854691 9.791799e-01 0.009 0 0
Intraflagellar transport R-HSA-5620924 9.794211e-01 0.009 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 9.796471e-01 0.009 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.807041e-01 0.008 0 0
NCAM1 interactions R-HSA-419037 9.807041e-01 0.008 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.814336e-01 0.008 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.814336e-01 0.008 0 0
CYP2E1 reactions R-HSA-211999 9.817843e-01 0.008 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.817843e-01 0.008 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.817843e-01 0.008 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.817843e-01 0.008 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.817843e-01 0.008 0 0
Synthesis of dolichyl-phosphate R-HSA-446199 9.817843e-01 0.008 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.821930e-01 0.008 0 0
Innate Immune System R-HSA-168249 9.824634e-01 0.008 0 0
Leishmania infection R-HSA-9658195 9.825119e-01 0.008 0 0
Parasitic Infection Pathways R-HSA-9824443 9.825119e-01 0.008 0 0
Elastic fibre formation R-HSA-1566948 9.827911e-01 0.008 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.840631e-01 0.007 0 0
Alpha-oxidation of phytanate R-HSA-389599 9.840631e-01 0.007 0 0
Signaling by FGFR in disease R-HSA-1226099 9.844388e-01 0.007 0 0
Viral Infection Pathways R-HSA-9824446 9.859813e-01 0.006 0 0
Linoleic acid (LA) metabolism R-HSA-2046105 9.860569e-01 0.006 0 0
Urea cycle R-HSA-70635 9.860569e-01 0.006 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.860569e-01 0.006 0 0
Extracellular matrix organization R-HSA-1474244 9.865425e-01 0.006 0 0
HCMV Early Events R-HSA-9609690 9.871707e-01 0.006 0 0
Gastrulation R-HSA-9758941 9.871772e-01 0.006 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.878013e-01 0.005 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 9.878013e-01 0.005 0 0
Synthesis of PE R-HSA-1483213 9.878013e-01 0.005 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.878013e-01 0.005 0 0
Formation of the cornified envelope R-HSA-6809371 9.879611e-01 0.005 0 0
Translation of Structural Proteins R-HSA-9694635 9.881527e-01 0.005 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.887726e-01 0.005 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.891521e-01 0.005 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.891521e-01 0.005 0 0
Translation of Structural Proteins R-HSA-9683701 9.891521e-01 0.005 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 9.893276e-01 0.005 0 0
Formation of the Early Elongation Complex R-HSA-113418 9.893276e-01 0.005 0 0
Pyrimidine salvage R-HSA-73614 9.893276e-01 0.005 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.898195e-01 0.004 0 0
Paracetamol ADME R-HSA-9753281 9.900807e-01 0.004 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.903421e-01 0.004 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.906631e-01 0.004 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 9.910162e-01 0.004 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.914042e-01 0.004 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.918146e-01 0.004 0 0
Dectin-2 family R-HSA-5621480 9.919778e-01 0.003 0 0
HCMV Infection R-HSA-9609646 9.920123e-01 0.003 0 0
Cargo concentration in the ER R-HSA-5694530 9.928537e-01 0.003 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.928537e-01 0.003 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.929277e-01 0.003 0 0
Retinoid metabolism and transport R-HSA-975634 9.931466e-01 0.003 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.931970e-01 0.003 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.937983e-01 0.003 0 0
tRNA processing R-HSA-72306 9.944123e-01 0.002 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.944995e-01 0.002 0 0
Recycling of bile acids and salts R-HSA-159418 9.945305e-01 0.002 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.945305e-01 0.002 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.946219e-01 0.002 0 0
Synthesis of PC R-HSA-1483191 9.946219e-01 0.002 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.949275e-01 0.002 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.952178e-01 0.002 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.952201e-01 0.002 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.953463e-01 0.002 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.953562e-01 0.002 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.957111e-01 0.002 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.958140e-01 0.002 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.962272e-01 0.002 0 0
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775 9.963380e-01 0.002 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.965796e-01 0.001 0 0
Signaling by GPCR R-HSA-372790 9.967169e-01 0.001 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.967965e-01 0.001 0 0
Glycosphingolipid transport R-HSA-9845576 9.967965e-01 0.001 0 0
Phenylalanine and tyrosine metabolism R-HSA-8963691 9.971975e-01 0.001 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.972706e-01 0.001 0 0
Metabolism of steroid hormones R-HSA-196071 9.972824e-01 0.001 0 0
O-linked glycosylation of mucins R-HSA-913709 9.975655e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.976291e-01 0.001 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.978554e-01 0.001 0 0
COPII-mediated vesicle transport R-HSA-204005 9.980479e-01 0.001 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.981551e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.982527e-01 0.001 0 0
Metabolism of cofactors R-HSA-8978934 9.982527e-01 0.001 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.983414e-01 0.001 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.983588e-01 0.001 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.987135e-01 0.001 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.987441e-01 0.001 0 0
tRNA Aminoacylation R-HSA-379724 9.988596e-01 0.000 0 0
Metabolism of polyamines R-HSA-351202 9.988596e-01 0.000 0 0
Potential therapeutics for SARS R-HSA-9679191 9.988828e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.988960e-01 0.000 0 0
Defensins R-HSA-1461973 9.989014e-01 0.000 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.989014e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.989252e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.989893e-01 0.000 0 0
Methylation R-HSA-156581 9.990390e-01 0.000 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.990390e-01 0.000 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.990390e-01 0.000 0 0
Surfactant metabolism R-HSA-5683826 9.990390e-01 0.000 0 0
mitochondrial fatty acid beta-oxidation of saturated fatty acids R-HSA-77286 9.991594e-01 0.000 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.991594e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.992015e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.992867e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.992972e-01 0.000 0 0
Xenobiotics R-HSA-211981 9.992972e-01 0.000 0 0
SLC transporter disorders R-HSA-5619102 9.993203e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.995120e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.995403e-01 0.000 0 0
Azathioprine ADME R-HSA-9748787 9.995695e-01 0.000 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.995695e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.995956e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.996143e-01 0.000 0 0
Post-translational protein modification R-HSA-597592 9.996509e-01 0.000 0 0
ECM proteoglycans R-HSA-3000178 9.997006e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.997006e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.997179e-01 0.000 0 0
Translation R-HSA-72766 9.997179e-01 0.000 0 0
Glucuronidation R-HSA-156588 9.997480e-01 0.000 0 0
Aspirin ADME R-HSA-9749641 9.997657e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.997657e-01 0.000 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 9.997928e-01 0.000 0 0
Digestion R-HSA-8935690 9.998072e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.998144e-01 0.000 0 0
Iron uptake and transport R-HSA-917937 9.998167e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.998189e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.998493e-01 0.000 0 0
Sialic acid metabolism R-HSA-4085001 9.998710e-01 0.000 0 0
Interleukin-10 signaling R-HSA-6783783 9.998733e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.999013e-01 0.000 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.999126e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999207e-01 0.000 0 0
Digestion and absorption R-HSA-8963743 9.999245e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999388e-01 0.000 0 0
Latent infection - Other responses of Mtb to phagocytosis R-HSA-1222499 9.999423e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.999437e-01 0.000 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.999543e-01 0.000 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.999543e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.999558e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.999705e-01 0.000 0 0
Metal ion assimilation from the host R-HSA-9638482 9.999742e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999743e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.999774e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999780e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.999881e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.999899e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999905e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.999907e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999919e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999942e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.999970e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999970e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999974e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999975e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999977e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999983e-01 0.000 0 0
Disease R-HSA-1643685 9.999984e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.999985e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.999990e-01 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 9.999990e-01 0.000 0 0
Scavenging of heme from plasma R-HSA-2168880 9.999993e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999994e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999995e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999995e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.999997e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999997e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999998e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999998e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999998e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.999999e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999999e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999999e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999999e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 1.000000e+00 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 1.000000e+00 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Nucleotide catabolism R-HSA-8956319 1.000000e+00 0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Mitochondrial translation R-HSA-5368287 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Cell Cycle, Mitotic R-HSA-69278 1.110223e-16 15.955 0 0
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 0 0
Cellular response to heat stress R-HSA-3371556 2.220446e-16 15.654 0 0
HSF1-dependent transactivation R-HSA-3371571 3.108624e-15 14.507 0 0
Attenuation phase R-HSA-3371568 1.310063e-14 13.883 0 0
Cellular responses to stress R-HSA-2262752 5.473400e-14 13.262 0 0
Cellular responses to stimuli R-HSA-8953897 6.655787e-13 12.177 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.932454e-12 11.714 0 0
Membrane Trafficking R-HSA-199991 4.122269e-11 10.385 0 0
HSF1 activation R-HSA-3371511 1.080160e-10 9.967 0 0
Mitotic Prometaphase R-HSA-68877 1.370006e-10 9.863 0 0
Mitotic Prophase R-HSA-68875 3.059696e-10 9.514 0 0
Aggrephagy R-HSA-9646399 5.815598e-10 9.235 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 5.953843e-10 9.225 0 0
Mitotic Anaphase R-HSA-68882 8.404997e-10 9.075 0 0
G2/M Transition R-HSA-69275 9.192652e-10 9.037 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 9.757999e-10 9.011 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.071169e-09 8.970 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.225981e-09 8.912 0 0
Separation of Sister Chromatids R-HSA-2467813 1.203193e-09 8.920 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.267739e-09 8.897 0 0
HDACs deacetylate histones R-HSA-3214815 1.551270e-09 8.809 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.804001e-09 8.744 0 0
Processing of DNA double-strand break ends R-HSA-5693607 2.355498e-09 8.628 0 0
Kinesins R-HSA-983189 7.176572e-09 8.144 0 0
Interleukin-12 signaling R-HSA-9020591 9.207705e-09 8.036 0 0
Cell Cycle Checkpoints R-HSA-69620 3.976546e-08 7.400 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 4.670021e-08 7.331 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 4.508473e-08 7.346 0 0
Recycling pathway of L1 R-HSA-437239 4.644961e-08 7.333 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 5.784829e-08 7.238 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 7.119985e-08 7.148 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 7.348494e-08 7.134 0 0
Transport of connexons to the plasma membrane R-HSA-190872 9.865938e-08 7.006 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.136830e-07 6.944 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.305467e-07 6.884 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.358480e-07 6.867 0 0
Apoptotic execution phase R-HSA-75153 1.466815e-07 6.834 0 0
Interleukin-12 family signaling R-HSA-447115 1.486312e-07 6.828 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 2.086726e-07 6.681 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 2.276611e-07 6.643 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 2.569523e-07 6.590 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.629596e-07 6.580 0 0
PKR-mediated signaling R-HSA-9833482 2.925103e-07 6.534 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 3.187111e-07 6.497 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 3.317984e-07 6.479 0 0
Gap junction trafficking R-HSA-190828 3.405362e-07 6.468 0 0
G2/M Checkpoints R-HSA-69481 3.406990e-07 6.468 0 0
Gap junction trafficking and regulation R-HSA-157858 3.485326e-07 6.458 0 0
Regulation of endogenous retroelements R-HSA-9842860 4.339908e-07 6.363 0 0
Homology Directed Repair R-HSA-5693538 5.034139e-07 6.298 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 5.145018e-07 6.289 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 5.501323e-07 6.260 0 0
Signaling by RAF1 mutants R-HSA-9656223 5.880849e-07 6.231 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 5.834738e-07 6.234 0 0
Selective autophagy R-HSA-9663891 5.834738e-07 6.234 0 0
Vesicle-mediated transport R-HSA-5653656 5.961717e-07 6.225 0 0
Metabolism of RNA R-HSA-8953854 6.715090e-07 6.173 0 0
Chromatin modifying enzymes R-HSA-3247509 7.123902e-07 6.147 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 6.932551e-07 6.159 0 0
Chromatin organization R-HSA-4839726 7.846373e-07 6.105 0 0
Meiosis R-HSA-1500620 8.267744e-07 6.083 0 0
G2/M DNA damage checkpoint R-HSA-69473 8.844286e-07 6.053 0 0
Cell-Cell communication R-HSA-1500931 9.391996e-07 6.027 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 9.552474e-07 6.020 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.272623e-06 5.895 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.572842e-06 5.803 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.900814e-06 5.721 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.901003e-06 5.721 0 0
DNA Double Strand Break Response R-HSA-5693606 2.159514e-06 5.666 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 2.196371e-06 5.658 0 0
Meiotic recombination R-HSA-912446 2.272045e-06 5.644 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.381428e-06 5.623 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.381428e-06 5.623 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.381428e-06 5.623 0 0
Signaling by RAS mutants R-HSA-6802949 2.381428e-06 5.623 0 0
L1CAM interactions R-HSA-373760 2.716581e-06 5.566 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 2.945825e-06 5.531 0 0
Cell junction organization R-HSA-446728 3.477432e-06 5.459 0 0
DNA Double-Strand Break Repair R-HSA-5693532 3.550630e-06 5.450 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 4.093907e-06 5.388 0 0
Axon guidance R-HSA-422475 4.711214e-06 5.327 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.917551e-06 5.308 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 5.277699e-06 5.278 0 0
TCF dependent signaling in response to WNT R-HSA-201681 5.582859e-06 5.253 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.077829e-06 5.150 0 0
PRC2 methylates histones and DNA R-HSA-212300 7.346480e-06 5.134 0 0
MHC class II antigen presentation R-HSA-2132295 7.705484e-06 5.113 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 8.818348e-06 5.055 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 8.818348e-06 5.055 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 8.910949e-06 5.050 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.031325e-05 4.987 0 0
Nervous system development R-HSA-9675108 1.060480e-05 4.974 0 0
HCMV Early Events R-HSA-9609690 1.092769e-05 4.961 0 0
Apoptosis R-HSA-109581 1.098195e-05 4.959 0 0
Signaling by WNT R-HSA-195721 1.100132e-05 4.959 0 0
DNA methylation R-HSA-5334118 1.222433e-05 4.913 0 0
Late endosomal microautophagy R-HSA-9615710 1.222433e-05 4.913 0 0
Meiotic synapsis R-HSA-1221632 1.291299e-05 4.889 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.291299e-05 4.889 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.276867e-05 4.894 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.286309e-05 4.891 0 0
Protein folding R-HSA-391251 1.252555e-05 4.902 0 0
Autophagy R-HSA-9612973 1.222113e-05 4.913 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.276867e-05 4.894 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.409883e-05 4.851 0 0
Viral Infection Pathways R-HSA-9824446 1.418106e-05 4.848 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.495897e-05 4.825 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.544868e-05 4.811 0 0
HCMV Infection R-HSA-9609646 1.648853e-05 4.783 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.675909e-05 4.776 0 0
Gap junction assembly R-HSA-190861 1.697785e-05 4.770 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.820093e-05 4.740 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.862586e-05 4.730 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.095493e-05 4.679 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.187087e-05 4.660 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 2.593493e-05 4.586 0 0
Programmed Cell Death R-HSA-5357801 3.099712e-05 4.509 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.758892e-05 4.425 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 3.913578e-05 4.407 0 0
Diseases of programmed cell death R-HSA-9645723 4.194006e-05 4.377 0 0
Josephin domain DUBs R-HSA-5689877 4.967149e-05 4.304 0 0
Striated Muscle Contraction R-HSA-390522 5.109880e-05 4.292 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.145600e-05 4.289 0 0
Deubiquitination R-HSA-5688426 5.097092e-05 4.293 0 0
Macroautophagy R-HSA-1632852 4.923100e-05 4.308 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 4.902552e-05 4.310 0 0
Defective pyroptosis R-HSA-9710421 5.550370e-05 4.256 0 0
HIV Life Cycle R-HSA-162587 6.881751e-05 4.162 0 0
COPI-mediated anterograde transport R-HSA-6807878 7.197056e-05 4.143 0 0
Nucleosome assembly R-HSA-774815 8.608765e-05 4.065 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.608765e-05 4.065 0 0
Ub-specific processing proteases R-HSA-5689880 9.081971e-05 4.042 0 0
Nuclear Envelope Breakdown R-HSA-2980766 9.431391e-05 4.025 0 0
Signal Transduction R-HSA-162582 8.732388e-05 4.059 0 0
Post NMDA receptor activation events R-HSA-438064 9.568181e-05 4.019 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.033343e-04 3.986 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.044699e-04 3.981 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.066096e-04 3.972 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.187586e-04 3.925 0 0
MAP2K and MAPK activation R-HSA-5674135 1.216665e-04 3.915 0 0
Cilium Assembly R-HSA-5617833 1.145533e-04 3.941 0 0
Muscle contraction R-HSA-397014 1.216042e-04 3.915 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.208813e-04 3.918 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.319260e-04 3.880 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.375334e-04 3.862 0 0
RNA Polymerase I Transcription R-HSA-73864 1.461797e-04 3.835 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.594004e-04 3.798 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.642298e-04 3.785 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.668206e-04 3.778 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.960579e-04 3.708 0 0
Adherens junctions interactions R-HSA-418990 2.058674e-04 3.686 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.058934e-04 3.686 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 2.129625e-04 3.672 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.279805e-04 3.642 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.298601e-04 3.639 0 0
HIV Infection R-HSA-162906 2.307327e-04 3.637 0 0
RAF activation R-HSA-5673000 2.411157e-04 3.618 0 0
Protein ubiquitination R-HSA-8852135 2.456241e-04 3.610 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.456241e-04 3.610 0 0
Cell-cell junction organization R-HSA-421270 2.463480e-04 3.608 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.479523e-04 3.606 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.479523e-04 3.606 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 2.576088e-04 3.589 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.715879e-04 3.566 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.715879e-04 3.566 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 2.829141e-04 3.548 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.374648e-04 3.472 0 0
Reproduction R-HSA-1474165 3.072383e-04 3.513 0 0
Interferon Signaling R-HSA-913531 3.416894e-04 3.466 0 0
DNA Repair R-HSA-73894 3.545695e-04 3.450 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 3.827222e-04 3.417 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 3.939174e-04 3.405 0 0
Regulation of TP53 Activity R-HSA-5633007 4.114278e-04 3.386 0 0
mRNA Splicing R-HSA-72172 4.379662e-04 3.359 0 0
DNA Replication Pre-Initiation R-HSA-69002 4.432061e-04 3.353 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.507713e-04 3.346 0 0
Amplification of signal from the kinetochores R-HSA-141424 4.640717e-04 3.333 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 4.640717e-04 3.333 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 4.652819e-04 3.332 0 0
Packaging Of Telomere Ends R-HSA-171306 4.695355e-04 3.328 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 4.909359e-04 3.309 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 4.966092e-04 3.304 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 5.340260e-04 3.272 0 0
HATs acetylate histones R-HSA-3214847 6.266479e-04 3.203 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 5.713627e-04 3.243 0 0
Host Interactions of HIV factors R-HSA-162909 6.061233e-04 3.217 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 6.638056e-04 3.178 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 6.638056e-04 3.178 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 6.661630e-04 3.176 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 6.676093e-04 3.175 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 6.684378e-04 3.175 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 6.971813e-04 3.157 0 0
Hedgehog 'off' state R-HSA-5610787 7.058029e-04 3.151 0 0
MAPK family signaling cascades R-HSA-5683057 7.337414e-04 3.134 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 7.485426e-04 3.126 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 7.485426e-04 3.126 0 0
Regulation of CDH1 Function R-HSA-9764561 7.846965e-04 3.105 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 7.893921e-04 3.103 0 0
Signaling by ALK in cancer R-HSA-9700206 7.893921e-04 3.103 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 7.950064e-04 3.100 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 7.950064e-04 3.100 0 0
Formation of annular gap junctions R-HSA-196025 8.021877e-04 3.096 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 8.021877e-04 3.096 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 8.455474e-04 3.073 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 8.455474e-04 3.073 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 8.835740e-04 3.054 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 9.154944e-04 3.038 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 9.177378e-04 3.037 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.083247e-03 2.965 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 9.683716e-04 3.014 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.102863e-03 2.957 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.019533e-03 2.992 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.058422e-03 2.975 0 0
Smooth Muscle Contraction R-HSA-445355 1.137137e-03 2.944 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.203799e-03 2.919 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.203799e-03 2.919 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.247307e-03 2.904 0 0
Gap junction degradation R-HSA-190873 1.247307e-03 2.904 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.251384e-03 2.903 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.261311e-03 2.899 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.288765e-03 2.890 0 0
Translation initiation complex formation R-HSA-72649 1.330014e-03 2.876 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.356720e-03 2.868 0 0
Intraflagellar transport R-HSA-5620924 1.405123e-03 2.852 0 0
Amyloid fiber formation R-HSA-977225 1.408173e-03 2.851 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.444463e-03 2.840 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.476360e-03 2.831 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.476360e-03 2.831 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.476360e-03 2.831 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.517126e-03 2.819 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.525457e-03 2.817 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.544373e-03 2.811 0 0
Centrosome maturation R-HSA-380287 1.565884e-03 2.805 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.575381e-03 2.803 0 0
Signaling by TGFB family members R-HSA-9006936 1.589717e-03 2.799 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.860304e-03 2.730 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.902784e-03 2.721 0 0
ER to Golgi Anterograde Transport R-HSA-199977 1.935181e-03 2.713 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.905949e-03 2.720 0 0
Signaling by PTK6 R-HSA-8848021 1.905949e-03 2.720 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 1.798802e-03 2.745 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.709805e-03 2.767 0 0
Gene Silencing by RNA R-HSA-211000 1.715602e-03 2.766 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.067796e-03 2.684 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 2.096985e-03 2.678 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 2.096985e-03 2.678 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 2.119636e-03 2.674 0 0
Influenza Infection R-HSA-168255 2.276172e-03 2.643 0 0
Signaling by ROBO receptors R-HSA-376176 2.318529e-03 2.635 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.429897e-03 2.614 0 0
Potential therapeutics for SARS R-HSA-9679191 2.494001e-03 2.603 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 2.518220e-03 2.599 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 2.518220e-03 2.599 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.553327e-03 2.593 0 0
Estrogen-dependent gene expression R-HSA-9018519 2.565462e-03 2.591 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 2.579701e-03 2.588 0 0
Clathrin-mediated endocytosis R-HSA-8856828 2.643596e-03 2.578 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 2.668170e-03 2.574 0 0
Regulation of signaling by CBL R-HSA-912631 2.675248e-03 2.573 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.675248e-03 2.573 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 2.675248e-03 2.573 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.708591e-03 2.567 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 2.807877e-03 2.552 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.821335e-03 2.550 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 2.821335e-03 2.550 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.821335e-03 2.550 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 2.835315e-03 2.547 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 2.835315e-03 2.547 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.892055e-03 2.539 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 2.975768e-03 2.526 0 0
Ribosome-associated quality control R-HSA-9948299 3.046980e-03 2.516 0 0
Regulation of PTEN localization R-HSA-8948747 3.138526e-03 2.503 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 3.138526e-03 2.503 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 3.413789e-03 2.467 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 3.413789e-03 2.467 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 3.413789e-03 2.467 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 3.413789e-03 2.467 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.109938e-03 2.507 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 3.109938e-03 2.507 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 3.270214e-03 2.485 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.153677e-03 2.501 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 3.636550e-03 2.439 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.674416e-03 2.435 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 3.512734e-03 2.454 0 0
RAF/MAP kinase cascade R-HSA-5673001 3.258470e-03 2.487 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 3.660341e-03 2.436 0 0
Glycolysis R-HSA-70171 3.373295e-03 2.472 0 0
Platelet degranulation R-HSA-114608 3.715084e-03 2.430 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 3.739107e-03 2.427 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.759120e-03 2.425 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.759120e-03 2.425 0 0
Budding and maturation of HIV virion R-HSA-162588 3.759120e-03 2.425 0 0
Formation of a pool of free 40S subunits R-HSA-72689 4.272738e-03 2.369 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 4.346253e-03 2.362 0 0
Cleavage of the damaged purine R-HSA-110331 4.346253e-03 2.362 0 0
HCMV Late Events R-HSA-9610379 4.354863e-03 2.361 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 4.380564e-03 2.358 0 0
Cellular Senescence R-HSA-2559583 4.404341e-03 2.356 0 0
SARS-CoV Infections R-HSA-9679506 4.615046e-03 2.336 0 0
Type I hemidesmosome assembly R-HSA-446107 4.674859e-03 2.330 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 4.674859e-03 2.330 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 4.674859e-03 2.330 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 4.674859e-03 2.330 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 4.674859e-03 2.330 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.765431e-03 2.322 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 4.842163e-03 2.315 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 4.983990e-03 2.302 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.045248e-03 2.297 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 5.073096e-03 2.295 0 0
VLDLR internalisation and degradation R-HSA-8866427 5.083947e-03 2.294 0 0
Depurination R-HSA-73927 5.112242e-03 2.291 0 0
Assembly Of The HIV Virion R-HSA-175474 5.356420e-03 2.271 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.376823e-03 2.269 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 5.376823e-03 2.269 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 5.491688e-03 2.260 0 0
Signaling by NOTCH R-HSA-157118 5.645116e-03 2.248 0 0
Signaling by Hedgehog R-HSA-5358351 5.746968e-03 2.241 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 5.872111e-03 2.231 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 5.981175e-03 2.223 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 7.187116e-03 2.143 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 7.187116e-03 2.143 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 7.187116e-03 2.143 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 7.187116e-03 2.143 0 0
Signaling by ERBB2 R-HSA-1227986 7.544781e-03 2.122 0 0
GP1b-IX-V activation signalling R-HSA-430116 6.681655e-03 2.175 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 6.681655e-03 2.175 0 0
PTEN Regulation R-HSA-6807070 6.214943e-03 2.207 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 7.544781e-03 2.122 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 7.544781e-03 2.122 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 7.544781e-03 2.122 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 7.544781e-03 2.122 0 0
Signaling by Hippo R-HSA-2028269 6.165836e-03 2.210 0 0
Calcineurin activates NFAT R-HSA-2025928 6.681655e-03 2.175 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 7.325751e-03 2.135 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 6.962136e-03 2.157 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 7.544781e-03 2.122 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 6.776776e-03 2.169 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 6.753240e-03 2.170 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 6.367214e-03 2.196 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 6.606447e-03 2.180 0 0
Nuclear import of Rev protein R-HSA-180746 7.493794e-03 2.125 0 0
Cytokine Signaling in Immune system R-HSA-1280215 7.487149e-03 2.126 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.558933e-03 2.122 0 0
ESR-mediated signaling R-HSA-8939211 7.732542e-03 2.112 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 7.895152e-03 2.103 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.895152e-03 2.103 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 7.979187e-03 2.098 0 0
Maturation of protein E R-HSA-9694493 8.028641e-03 2.095 0 0
Maturation of protein E R-HSA-9683683 8.028641e-03 2.095 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 8.413765e-03 2.075 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 8.768273e-03 2.057 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 8.787575e-03 2.056 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 9.034403e-03 2.044 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 9.224906e-03 2.035 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 9.224906e-03 2.035 0 0
Folding of actin by CCT/TriC R-HSA-390450 9.224906e-03 2.035 0 0
Pexophagy R-HSA-9664873 9.224906e-03 2.035 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 9.224906e-03 2.035 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.297655e-03 2.032 0 0
rRNA processing R-HSA-72312 9.396020e-03 2.027 0 0
Hemostasis R-HSA-109582 9.457410e-03 2.024 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.731113e-03 2.012 0 0
FLT3 signaling in disease R-HSA-9682385 1.020255e-02 1.991 0 0
Glucose metabolism R-HSA-70326 1.028376e-02 1.988 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 1.039165e-02 1.983 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.067143e-02 1.972 0 0
Depyrimidination R-HSA-73928 1.067143e-02 1.972 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 1.102636e-02 1.958 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.122665e-02 1.950 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.122665e-02 1.950 0 0
Spry regulation of FGF signaling R-HSA-1295596 1.122665e-02 1.950 0 0
p75NTR signals via NF-kB R-HSA-193639 1.122665e-02 1.950 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.164203e-02 1.934 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.164203e-02 1.934 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 1.164203e-02 1.934 0 0
Negative regulation of MET activity R-HSA-6807004 1.183191e-02 1.927 0 0
Nephrin family interactions R-HSA-373753 1.183191e-02 1.927 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 1.193366e-02 1.923 0 0
Eukaryotic Translation Elongation R-HSA-156842 1.212755e-02 1.916 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 1.236656e-02 1.908 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.236656e-02 1.908 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 1.236656e-02 1.908 0 0
Signaling by MET R-HSA-6806834 1.348973e-02 1.870 0 0
Chromosome Maintenance R-HSA-73886 1.401976e-02 1.853 0 0
Prolonged ERK activation events R-HSA-169893 1.410857e-02 1.851 0 0
Negative regulation of FLT3 R-HSA-9706369 1.410857e-02 1.851 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.436274e-02 1.843 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.436274e-02 1.843 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.495235e-02 1.825 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.500628e-02 1.824 0 0
Regulation of necroptotic cell death R-HSA-5675482 1.500628e-02 1.824 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 1.500628e-02 1.824 0 0
Metabolism of non-coding RNA R-HSA-194441 1.522464e-02 1.817 0 0
snRNP Assembly R-HSA-191859 1.522464e-02 1.817 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.638622e-02 1.786 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.638622e-02 1.786 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.638622e-02 1.786 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.638622e-02 1.786 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.638622e-02 1.786 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.688293e-02 1.773 0 0
Signaling by AMER1 mutants R-HSA-4839748 1.616317e-02 1.791 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 1.746928e-02 1.758 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.629982e-02 1.788 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 1.995416e-02 1.700 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 1.995416e-02 1.700 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 1.573416e-02 1.803 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 1.711708e-02 1.767 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 1.945365e-02 1.711 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.019052e-02 1.695 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 1.725792e-02 1.763 0 0
Resolution of D-Loop Structures R-HSA-5693537 1.735194e-02 1.761 0 0
NF-kB is activated and signals survival R-HSA-209560 1.616317e-02 1.791 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.631246e-02 1.787 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 2.028497e-02 1.693 0 0
Activation of HOX genes during differentiation R-HSA-5619507 2.028497e-02 1.693 0 0
Repression of WNT target genes R-HSA-4641265 2.066479e-02 1.685 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.616317e-02 1.791 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.746928e-02 1.758 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.625195e-02 1.789 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 1.995416e-02 1.700 0 0
Signaling by NOTCH1 R-HSA-1980143 1.884806e-02 1.725 0 0
IRAK1 recruits IKK complex R-HSA-937039 2.066479e-02 1.685 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 2.066479e-02 1.685 0 0
DNA Replication R-HSA-69306 1.788972e-02 1.747 0 0
Co-inhibition by PD-1 R-HSA-389948 1.577342e-02 1.802 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 2.066479e-02 1.685 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 2.066479e-02 1.685 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 2.054174e-02 1.687 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 1.777774e-02 1.750 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 2.019052e-02 1.695 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.677907e-02 1.775 0 0
p75NTR recruits signalling complexes R-HSA-209543 2.066479e-02 1.685 0 0
SARS-CoV-1 Infection R-HSA-9678108 1.590996e-02 1.798 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.600984e-02 1.796 0 0
tRNA processing in the nucleus R-HSA-6784531 2.084709e-02 1.681 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.106886e-02 1.676 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.106886e-02 1.676 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.134196e-02 1.671 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.159111e-02 1.666 0 0
Platelet calcium homeostasis R-HSA-418360 2.217148e-02 1.654 0 0
Regulation of Apoptosis R-HSA-169911 2.282692e-02 1.642 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 2.282692e-02 1.642 0 0
PERK regulates gene expression R-HSA-381042 2.282692e-02 1.642 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 2.295023e-02 1.639 0 0
Modulation by Mtb of host immune system R-HSA-9637628 2.295023e-02 1.639 0 0
Semaphorin interactions R-HSA-373755 2.302863e-02 1.638 0 0
TNF signaling R-HSA-75893 2.411306e-02 1.618 0 0
Ion homeostasis R-HSA-5578775 2.411306e-02 1.618 0 0
Infectious disease R-HSA-5663205 2.450378e-02 1.611 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 2.538965e-02 1.595 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.575658e-02 1.589 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 2.575658e-02 1.589 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 2.591417e-02 1.586 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.591417e-02 1.586 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.598365e-02 1.585 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 2.627677e-02 1.580 0 0
Regulation of RAS by GAPs R-HSA-5658442 2.789172e-02 1.555 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.800660e-02 1.553 0 0
Trafficking of AMPA receptors R-HSA-399719 2.939633e-02 1.532 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.939633e-02 1.532 0 0
Degradation of AXIN R-HSA-4641257 2.943708e-02 1.531 0 0
Degradation of DVL R-HSA-4641258 2.943708e-02 1.531 0 0
Peptide chain elongation R-HSA-156902 2.951498e-02 1.530 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.959305e-02 1.529 0 0
ARMS-mediated activation R-HSA-170984 3.018813e-02 1.520 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 3.018813e-02 1.520 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.018813e-02 1.520 0 0
Translesion Synthesis by POLH R-HSA-110320 3.073951e-02 1.512 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.119844e-02 1.506 0 0
Signaling by NOTCH4 R-HSA-9013694 3.131901e-02 1.504 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.153162e-02 1.501 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 3.172404e-02 1.499 0 0
Adaptive Immune System R-HSA-1280218 3.179028e-02 1.498 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 3.194620e-02 1.496 0 0
NRIF signals cell death from the nucleus R-HSA-205043 3.194620e-02 1.496 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 3.194620e-02 1.496 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 3.246043e-02 1.489 0 0
Sema4D in semaphorin signaling R-HSA-400685 3.294289e-02 1.482 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 3.319913e-02 1.479 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 3.319913e-02 1.479 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.405001e-02 1.468 0 0
Opioid Signalling R-HSA-111885 3.405001e-02 1.468 0 0
Orc1 removal from chromatin R-HSA-68949 3.427129e-02 1.465 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.433580e-02 1.464 0 0
Manipulation of host energy metabolism R-HSA-9636667 3.461966e-02 1.461 0 0
Breakdown of the nuclear lamina R-HSA-352238 3.461966e-02 1.461 0 0
Signaling by VEGF R-HSA-194138 3.468507e-02 1.460 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 3.592733e-02 1.445 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 3.631319e-02 1.440 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 3.631319e-02 1.440 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.344372e-02 1.362 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.828362e-02 1.316 0 0
Signaling by APC mutants R-HSA-4839744 4.828362e-02 1.316 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 4.828362e-02 1.316 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 4.828362e-02 1.316 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 4.828362e-02 1.316 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 3.878759e-02 1.411 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 3.878759e-02 1.411 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 4.645670e-02 1.333 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 4.645670e-02 1.333 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.496366e-02 1.260 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 4.249591e-02 1.372 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 4.930166e-02 1.307 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 4.930166e-02 1.307 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.351757e-02 1.361 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 4.837123e-02 1.315 0 0
Dual Incision in GG-NER R-HSA-5696400 4.837123e-02 1.315 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 3.715693e-02 1.430 0 0
Post-translational protein phosphorylation R-HSA-8957275 3.961343e-02 1.402 0 0
Signaling by EGFR in Cancer R-HSA-1643713 3.798923e-02 1.420 0 0
Regulation of PTEN stability and activity R-HSA-8948751 3.781940e-02 1.422 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 3.781940e-02 1.422 0 0
Metalloprotease DUBs R-HSA-5689901 3.798923e-02 1.420 0 0
Regulation of TNFR1 signaling R-HSA-5357905 3.987897e-02 1.399 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 3.862849e-02 1.413 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 3.809626e-02 1.419 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 4.837123e-02 1.315 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 5.412372e-02 1.267 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 5.412372e-02 1.267 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 4.644241e-02 1.333 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 4.644241e-02 1.333 0 0
PCP/CE pathway R-HSA-4086400 4.345402e-02 1.362 0 0
Telomere Maintenance R-HSA-157579 3.690595e-02 1.433 0 0
Stabilization of p53 R-HSA-69541 3.728084e-02 1.429 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.728084e-02 1.429 0 0
Death Receptor Signaling R-HSA-73887 5.041012e-02 1.297 0 0
Transmission across Chemical Synapses R-HSA-112315 5.373426e-02 1.270 0 0
Signaling by EGFR R-HSA-177929 4.998196e-02 1.301 0 0
Disorders of Developmental Biology R-HSA-9675151 5.496366e-02 1.260 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 4.169226e-02 1.380 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 5.349279e-02 1.272 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 5.349279e-02 1.272 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 4.645670e-02 1.333 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 3.809626e-02 1.419 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 4.953962e-02 1.305 0 0
Vpu mediated degradation of CD4 R-HSA-180534 4.303158e-02 1.366 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 4.837123e-02 1.315 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.728084e-02 1.429 0 0
Signaling by Nuclear Receptors R-HSA-9006931 4.392072e-02 1.357 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 5.491981e-02 1.260 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 4.249591e-02 1.372 0 0
Diseases of DNA repair R-HSA-9675135 3.987897e-02 1.399 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 4.249591e-02 1.372 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 3.878759e-02 1.411 0 0
SARS-CoV-2 Infection R-HSA-9694516 3.671385e-02 1.435 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 4.930166e-02 1.307 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 4.930166e-02 1.307 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 4.161619e-02 1.381 0 0
Circadian clock R-HSA-9909396 5.563963e-02 1.255 0 0
Eukaryotic Translation Termination R-HSA-72764 5.655797e-02 1.248 0 0
Ca-dependent events R-HSA-111996 5.698919e-02 1.244 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.698919e-02 1.244 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 5.741727e-02 1.241 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 5.741727e-02 1.241 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 5.741727e-02 1.241 0 0
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) R-HSA-1299308 5.782198e-02 1.238 0 0
Signaling by GSK3beta mutants R-HSA-5339716 5.914777e-02 1.228 0 0
Signaling by AXIN mutants R-HSA-4839735 5.914777e-02 1.228 0 0
CaM pathway R-HSA-111997 6.029578e-02 1.220 0 0
Calmodulin induced events R-HSA-111933 6.029578e-02 1.220 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 6.029578e-02 1.220 0 0
Signaling by Interleukins R-HSA-449147 6.109662e-02 1.214 0 0
Cellular response to starvation R-HSA-9711097 6.175817e-02 1.209 0 0
RSV-host interactions R-HSA-9833110 6.268111e-02 1.203 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 6.279798e-02 1.202 0 0
TBC/RABGAPs R-HSA-8854214 6.279798e-02 1.202 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 6.377232e-02 1.195 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 6.407362e-02 1.193 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.409651e-02 1.193 0 0
Hedgehog ligand biogenesis R-HSA-5358346 6.409651e-02 1.193 0 0
Neutrophil degranulation R-HSA-6798695 6.409922e-02 1.193 0 0
Translation R-HSA-72766 6.418063e-02 1.193 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 6.431055e-02 1.192 0 0
Glycogen storage diseases R-HSA-3229121 6.431055e-02 1.192 0 0
G-protein mediated events R-HSA-112040 6.437839e-02 1.191 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 6.465570e-02 1.189 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 6.590682e-02 1.181 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 6.659795e-02 1.177 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 6.689237e-02 1.175 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 6.896971e-02 1.161 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 6.944919e-02 1.158 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 6.987068e-02 1.156 0 0
IRE1alpha activates chaperones R-HSA-381070 7.031417e-02 1.153 0 0
EGFR downregulation R-HSA-182971 7.064540e-02 1.151 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 7.064540e-02 1.151 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 7.119886e-02 1.148 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 7.119886e-02 1.148 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 7.119886e-02 1.148 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 7.119886e-02 1.148 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 7.119886e-02 1.148 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 7.119886e-02 1.148 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 7.282285e-02 1.138 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 7.353103e-02 1.134 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 7.392710e-02 1.131 0 0
TRIF-mediated programmed cell death R-HSA-2562578 7.392710e-02 1.131 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 7.392710e-02 1.131 0 0
Cellular response to chemical stress R-HSA-9711123 7.430130e-02 1.129 0 0
DAG and IP3 signaling R-HSA-1489509 7.550728e-02 1.122 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 7.550728e-02 1.122 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 7.550728e-02 1.122 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 7.550728e-02 1.122 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 7.550728e-02 1.122 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.563971e-02 1.121 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.596373e-02 1.119 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 7.810414e-02 1.107 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.870613e-02 1.104 0 0
G alpha (12/13) signalling events R-HSA-416482 7.874314e-02 1.104 0 0
Plasma lipoprotein clearance R-HSA-8964043 8.136982e-02 1.090 0 0
XBP1(S) activates chaperone genes R-HSA-381038 8.200964e-02 1.086 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 8.237744e-02 1.084 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.241226e-02 1.084 0 0
Regulation of pyruvate metabolism R-HSA-9861718 8.241226e-02 1.084 0 0
Long-term potentiation R-HSA-9620244 8.288105e-02 1.082 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 8.440045e-02 1.074 0 0
Frs2-mediated activation R-HSA-170968 8.440045e-02 1.074 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 8.492578e-02 1.071 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 8.492578e-02 1.071 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 8.492578e-02 1.071 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 8.549428e-02 1.068 0 0
Rap1 signalling R-HSA-392517 8.549428e-02 1.068 0 0
Integrin signaling R-HSA-354192 8.727897e-02 1.059 0 0
Nuclear RNA decay R-HSA-9930044 8.727897e-02 1.059 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 8.727897e-02 1.059 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 8.727897e-02 1.059 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 8.787124e-02 1.056 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 8.787124e-02 1.056 0 0
MyD88-independent TLR4 cascade R-HSA-166166 8.864888e-02 1.052 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 8.864888e-02 1.052 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 8.911262e-02 1.050 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 8.968491e-02 1.047 0 0
Gene expression (Transcription) R-HSA-74160 9.040303e-02 1.044 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 9.189985e-02 1.037 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 9.189985e-02 1.037 0 0
Viral mRNA Translation R-HSA-192823 9.192206e-02 1.037 0 0
Deletions in the AMER1 gene destabilize the destruction complex R-HSA-5467343 9.199623e-02 1.036 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 9.199623e-02 1.036 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 9.285875e-02 1.032 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.342381e-02 1.030 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 9.616904e-02 1.017 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 9.616904e-02 1.017 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 9.635958e-02 1.016 0 0
Glycogen synthesis R-HSA-3322077 9.729860e-02 1.012 0 0
FLT3 Signaling R-HSA-9607240 9.755909e-02 1.011 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.755909e-02 1.011 0 0
ER-Phagosome pathway R-HSA-1236974 9.859730e-02 1.006 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.861587e-02 1.006 0 0
Ca2+ pathway R-HSA-4086398 9.861587e-02 1.006 0 0
Inositol phosphate metabolism R-HSA-1483249 9.864358e-02 1.006 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 9.870364e-02 1.006 0 0
PIP3 activates AKT signaling R-HSA-1257604 9.960869e-02 1.002 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.052172e-01 0.978 0 0
DNA Damage Bypass R-HSA-73893 1.053276e-01 0.977 0 0
Degradation of CDH1 R-HSA-9766229 1.053276e-01 0.977 0 0
Signaling by NOTCH2 R-HSA-1980145 1.059411e-01 0.975 0 0
Degradation of CRY and PER proteins R-HSA-9932298 1.062886e-01 0.974 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 1.062886e-01 0.974 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 1.062886e-01 0.974 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 1.062886e-01 0.974 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 1.065888e-01 0.972 0 0
Nucleotide Excision Repair R-HSA-5696398 1.081499e-01 0.966 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 1.098789e-01 0.959 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.140491e-01 0.943 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.140491e-01 0.943 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 1.140491e-01 0.943 0 0
G beta:gamma signalling through BTK R-HSA-8964315 1.140491e-01 0.943 0 0
Translesion synthesis by REV1 R-HSA-110312 1.140491e-01 0.943 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.140491e-01 0.943 0 0
Protein methylation R-HSA-8876725 1.140491e-01 0.943 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 1.140491e-01 0.943 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.140491e-01 0.943 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.146477e-01 0.941 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 1.149076e-01 0.940 0 0
Regulation of gap junction activity R-HSA-191650 1.150178e-01 0.939 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 1.150178e-01 0.939 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.150178e-01 0.939 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.154342e-01 0.938 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 1.154342e-01 0.938 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 1.154342e-01 0.938 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.160141e-01 0.935 0 0
Protein-protein interactions at synapses R-HSA-6794362 1.217717e-01 0.914 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.232038e-01 0.909 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.232038e-01 0.909 0 0
Regulated Necrosis R-HSA-5218859 1.234245e-01 0.909 0 0
EPH-Ephrin signaling R-HSA-2682334 1.236900e-01 0.908 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.249883e-01 0.903 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 1.755341e-01 0.756 0 0
Hereditary fructose intolerance R-HSA-5657560 1.755341e-01 0.756 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 1.755341e-01 0.756 0 0
TICAM1 deficiency - HSE R-HSA-5602566 1.755341e-01 0.756 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 1.755341e-01 0.756 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 1.755341e-01 0.756 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 1.755341e-01 0.756 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.755341e-01 0.756 0 0
IRS activation R-HSA-74713 1.473196e-01 0.832 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 1.473196e-01 0.832 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 1.473196e-01 0.832 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 1.811706e-01 0.742 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.811706e-01 0.742 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 1.811706e-01 0.742 0 0
Signaling by LTK in cancer R-HSA-9842640 2.160129e-01 0.666 0 0
Translesion synthesis by POLI R-HSA-5656121 1.303688e-01 0.885 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.303688e-01 0.885 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 2.513778e-01 0.600 0 0
SOS-mediated signalling R-HSA-112412 2.513778e-01 0.600 0 0
Recycling of eIF2:GDP R-HSA-72731 2.513778e-01 0.600 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 2.513778e-01 0.600 0 0
Translesion synthesis by POLK R-HSA-5655862 1.475880e-01 0.831 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 2.022339e-01 0.694 0 0
FGFR2 alternative splicing R-HSA-6803529 1.372372e-01 0.863 0 0
Notch-HLH transcription pathway R-HSA-350054 1.372372e-01 0.863 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 2.271259e-01 0.644 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.844021e-01 0.734 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 1.844021e-01 0.734 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 1.831671e-01 0.737 0 0
G protein gated Potassium channels R-HSA-1296059 1.831671e-01 0.737 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 1.831671e-01 0.737 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.788860e-01 0.747 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 2.165059e-01 0.665 0 0
Cristae formation R-HSA-8949613 2.165059e-01 0.665 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.314803e-01 0.881 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 1.732696e-01 0.761 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 1.732696e-01 0.761 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 1.408915e-01 0.851 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 2.079264e-01 0.682 0 0
GABA B receptor activation R-HSA-977444 2.124704e-01 0.673 0 0
Activation of GABAB receptors R-HSA-991365 2.124704e-01 0.673 0 0
mRNA 3'-end processing R-HSA-72187 2.273796e-01 0.643 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.273796e-01 0.643 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.402927e-01 0.619 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.272699e-01 0.643 0 0
Early Phase of HIV Life Cycle R-HSA-162594 2.442853e-01 0.612 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 1.990500e-01 0.701 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.452835e-01 0.838 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 1.780450e-01 0.749 0 0
Integration of provirus R-HSA-162592 1.780450e-01 0.749 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 1.375857e-01 0.861 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 1.859752e-01 0.731 0 0
PI3K/AKT activation R-HSA-198203 1.324843e-01 0.878 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 1.303688e-01 0.885 0 0
Polo-like kinase mediated events R-HSA-156711 1.844021e-01 0.734 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 1.995979e-01 0.700 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.314803e-01 0.881 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.395949e-01 0.855 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.568311e-01 0.805 0 0
Neurexins and neuroligins R-HSA-6794361 2.273796e-01 0.643 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 1.480825e-01 0.829 0 0
Regulation of mitotic cell cycle R-HSA-453276 1.480825e-01 0.829 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 2.271259e-01 0.644 0 0
PLC beta mediated events R-HSA-112043 1.361935e-01 0.866 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 2.165059e-01 0.665 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 1.324843e-01 0.878 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.238177e-01 0.650 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 2.230361e-01 0.652 0 0
Signaling by WNT in cancer R-HSA-4791275 1.650222e-01 0.782 0 0
Signal amplification R-HSA-392518 2.079264e-01 0.682 0 0
Activation and oligomerization of BAK protein R-HSA-111452 1.755341e-01 0.756 0 0
Inositol transporters R-HSA-429593 1.473196e-01 0.832 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 2.513778e-01 0.600 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 1.656269e-01 0.781 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.452835e-01 0.838 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 1.844021e-01 0.734 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.672643e-01 0.777 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 1.995979e-01 0.700 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.630837e-01 0.788 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.811706e-01 0.742 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 2.513778e-01 0.600 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 1.452835e-01 0.838 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.272130e-01 0.644 0 0
MET promotes cell motility R-HSA-8875878 1.490546e-01 0.827 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 2.419210e-01 0.616 0 0
TRP channels R-HSA-3295583 1.995979e-01 0.700 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 1.560018e-01 0.807 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 2.446835e-01 0.611 0 0
S Phase R-HSA-69242 1.880402e-01 0.726 0 0
Antigen processing-Cross presentation R-HSA-1236975 1.906540e-01 0.720 0 0
Platelet sensitization by LDL R-HSA-432142 1.844021e-01 0.734 0 0
Pentose phosphate pathway R-HSA-71336 1.609558e-01 0.793 0 0
Neuronal System R-HSA-112316 1.405624e-01 0.852 0 0
G1/S Transition R-HSA-69206 2.024246e-01 0.694 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.425138e-01 0.615 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 1.755341e-01 0.756 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.755341e-01 0.756 0 0
Inhibition of PKR R-HSA-169131 1.755341e-01 0.756 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 1.473196e-01 0.832 0 0
Signaling by LTK R-HSA-9842663 2.022339e-01 0.694 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 1.264253e-01 0.898 0 0
Neurodegenerative Diseases R-HSA-8863678 1.672643e-01 0.777 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.672643e-01 0.777 0 0
RMTs methylate histone arginines R-HSA-3214858 1.349416e-01 0.870 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.079264e-01 0.682 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.079264e-01 0.682 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 2.079264e-01 0.682 0 0
Post-translational protein modification R-HSA-597592 1.938563e-01 0.713 0 0
Metabolism of proteins R-HSA-392499 1.969852e-01 0.706 0 0
Platelet homeostasis R-HSA-418346 1.748287e-01 0.757 0 0
Signalling to ERKs R-HSA-187687 2.230361e-01 0.652 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 1.788860e-01 0.747 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.165059e-01 0.665 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.451181e-01 0.838 0 0
RNA Polymerase II Transcription R-HSA-73857 2.282322e-01 0.642 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.811706e-01 0.742 0 0
Nef and signal transduction R-HSA-164944 2.160129e-01 0.666 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 2.513778e-01 0.600 0 0
CHL1 interactions R-HSA-447041 2.513778e-01 0.600 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 2.022339e-01 0.694 0 0
Disorders of Nervous System Development R-HSA-9697154 2.022339e-01 0.694 0 0
Pervasive developmental disorders R-HSA-9005895 2.022339e-01 0.694 0 0
Basigin interactions R-HSA-210991 2.442853e-01 0.612 0 0
Cellular response to hypoxia R-HSA-1234174 1.736166e-01 0.760 0 0
Signaling by FGFR2 R-HSA-5654738 1.500992e-01 0.824 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.480825e-01 0.829 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 2.338390e-01 0.631 0 0
Rab regulation of trafficking R-HSA-9007101 2.048297e-01 0.689 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.693751e-01 0.771 0 0
Gluconeogenesis R-HSA-70263 1.785125e-01 0.748 0 0
Mitophagy R-HSA-5205647 2.079264e-01 0.682 0 0
MAP kinase activation R-HSA-450294 2.272699e-01 0.643 0 0
Immune System R-HSA-168256 2.302631e-01 0.638 0 0
Signaling by FGFR4 R-HSA-5654743 2.262117e-01 0.645 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 1.473196e-01 0.832 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 1.811706e-01 0.742 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.303688e-01 0.885 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.361935e-01 0.866 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 2.147261e-01 0.668 0 0
Disease R-HSA-1643685 2.298922e-01 0.638 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 2.262021e-01 0.646 0 0
Pyruvate metabolism R-HSA-70268 1.436536e-01 0.843 0 0
Signaling by ERBB4 R-HSA-1236394 1.750856e-01 0.757 0 0
Ion transport by P-type ATPases R-HSA-936837 1.638378e-01 0.786 0 0
Base Excision Repair R-HSA-73884 1.675047e-01 0.776 0 0
TCR signaling R-HSA-202403 2.071376e-01 0.684 0 0
CASP4 inflammasome assembly R-HSA-9948001 1.324843e-01 0.878 0 0
Selenocysteine synthesis R-HSA-2408557 1.316175e-01 0.881 0 0
Hedgehog 'on' state R-HSA-5632684 1.480825e-01 0.829 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.038279e-01 0.691 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 2.022339e-01 0.694 0 0
G1/S-Specific Transcription R-HSA-69205 1.265669e-01 0.898 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 1.927460e-01 0.715 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 2.042476e-01 0.690 0 0
Interleukin-7 signaling R-HSA-1266695 1.831671e-01 0.737 0 0
Sensory processing of sound R-HSA-9659379 1.420056e-01 0.848 0 0
Signaling by NOTCH3 R-HSA-9012852 1.607052e-01 0.794 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 1.475880e-01 0.831 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 2.271259e-01 0.644 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.238177e-01 0.650 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 1.940498e-01 0.712 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 1.844021e-01 0.734 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 2.442853e-01 0.612 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 2.079264e-01 0.682 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 2.442853e-01 0.612 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.758733e-01 0.755 0 0
Regulation of BACH1 activity R-HSA-9708530 1.303688e-01 0.885 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.442853e-01 0.612 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.609558e-01 0.793 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 2.513908e-01 0.600 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 2.513908e-01 0.600 0 0
Defective GFPT1 causes CMSTA1 R-HSA-4085023 2.513908e-01 0.600 0 0
TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P R-HSA-6791462 2.513908e-01 0.600 0 0
IKBKB deficiency causes SCID R-HSA-5602636 2.513908e-01 0.600 0 0
Defective HK1 causes hexokinase deficiency (HK deficiency) R-HSA-5619056 2.513908e-01 0.600 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.513908e-01 0.600 0 0
TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P R-HSA-6791055 2.513908e-01 0.600 0 0
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) R-HSA-5619039 2.513908e-01 0.600 0 0
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) R-HSA-5603027 2.513908e-01 0.600 0 0
TRAF3 deficiency - HSE R-HSA-5602571 2.513908e-01 0.600 0 0
Nef mediated downregulation of CD28 cell surface expression R-HSA-164939 2.513908e-01 0.600 0 0
Transport of connexins along the secretory pathway R-HSA-190827 2.513908e-01 0.600 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.513908e-01 0.600 0 0
Oligomerization of connexins into connexons R-HSA-190704 2.513908e-01 0.600 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 2.515446e-01 0.599 0 0
Termination of translesion DNA synthesis R-HSA-5656169 2.515446e-01 0.599 0 0
DARPP-32 events R-HSA-180024 2.515446e-01 0.599 0 0
Non-canonical inflammasome activation R-HSA-9686114 2.525533e-01 0.598 0 0
Downstream TCR signaling R-HSA-202424 2.533000e-01 0.596 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 2.534454e-01 0.596 0 0
Signaling by FGFR3 R-HSA-5654741 2.545548e-01 0.594 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 2.584254e-01 0.588 0 0
Developmental Cell Lineages R-HSA-9734767 2.626885e-01 0.581 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 2.638843e-01 0.579 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 2.651454e-01 0.577 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 2.651454e-01 0.577 0 0
G alpha (z) signalling events R-HSA-418597 2.668172e-01 0.574 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.695698e-01 0.569 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 2.695698e-01 0.569 0 0
Activation of BH3-only proteins R-HSA-114452 2.695698e-01 0.569 0 0
Developmental Biology R-HSA-1266738 2.764278e-01 0.558 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 2.783581e-01 0.555 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 2.783581e-01 0.555 0 0
ABC-family proteins mediated transport R-HSA-382556 2.797565e-01 0.553 0 0
Generic Transcription Pathway R-HSA-212436 2.809162e-01 0.551 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 2.838685e-01 0.547 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 2.838685e-01 0.547 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 2.863148e-01 0.543 0 0
mTORC1-mediated signalling R-HSA-166208 2.863148e-01 0.543 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 2.865790e-01 0.543 0 0
ALKBH3 mediated reversal of alkylation damage R-HSA-112126 2.868748e-01 0.542 0 0
Regulation by c-FLIP R-HSA-3371378 2.868748e-01 0.542 0 0
Dimerization of procaspase-8 R-HSA-69416 2.868748e-01 0.542 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 2.868748e-01 0.542 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 2.868748e-01 0.542 0 0
UCH proteinases R-HSA-5689603 2.963573e-01 0.528 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 3.021798e-01 0.520 0 0
Glycogen metabolism R-HSA-8982491 3.030593e-01 0.518 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 3.043930e-01 0.517 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 3.043930e-01 0.517 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 3.043930e-01 0.517 0 0
G0 and Early G1 R-HSA-1538133 3.063700e-01 0.514 0 0
Inwardly rectifying K+ channels R-HSA-1296065 3.063700e-01 0.514 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.077126e-01 0.512 0 0
Syndecan interactions R-HSA-3000170 3.077126e-01 0.512 0 0
Transcription of the HIV genome R-HSA-167172 3.152017e-01 0.501 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 3.197048e-01 0.495 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 3.202723e-01 0.494 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 3.202723e-01 0.494 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 3.202723e-01 0.494 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 3.202723e-01 0.494 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 3.202723e-01 0.494 0 0
mRNA Editing: A to I Conversion R-HSA-75064 3.202723e-01 0.494 0 0
C6 deamination of adenosine R-HSA-75102 3.202723e-01 0.494 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 3.202723e-01 0.494 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 3.202723e-01 0.494 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 3.211052e-01 0.493 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.221803e-01 0.492 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.221803e-01 0.492 0 0
Lipophagy R-HSA-9613354 3.221803e-01 0.492 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.221803e-01 0.492 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 3.221803e-01 0.492 0 0
CASP8 activity is inhibited R-HSA-5218900 3.221803e-01 0.492 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 3.221803e-01 0.492 0 0
ALK mutants bind TKIs R-HSA-9700645 3.221803e-01 0.492 0 0
Regulated proteolysis of p75NTR R-HSA-193692 3.221803e-01 0.492 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.221803e-01 0.492 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.221803e-01 0.492 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 3.221803e-01 0.492 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.221803e-01 0.492 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.221803e-01 0.492 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 3.221803e-01 0.492 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 3.250423e-01 0.488 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.292616e-01 0.482 0 0
Deadenylation of mRNA R-HSA-429947 3.292616e-01 0.482 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 3.292616e-01 0.482 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 3.292616e-01 0.482 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 3.305219e-01 0.481 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 3.305219e-01 0.481 0 0
Interleukin-17 signaling R-HSA-448424 3.416260e-01 0.466 0 0
Adipogenesis R-HSA-9843745 3.487844e-01 0.457 0 0
Cardiac conduction R-HSA-5576891 3.487844e-01 0.457 0 0
Aquaporin-mediated transport R-HSA-445717 3.504759e-01 0.455 0 0
HDMs demethylate histones R-HSA-3214842 3.508880e-01 0.455 0 0
Tight junction interactions R-HSA-420029 3.508880e-01 0.455 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.508880e-01 0.455 0 0
TGFBR3 expression R-HSA-9839394 3.508880e-01 0.455 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.566203e-01 0.448 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.566203e-01 0.448 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 3.566203e-01 0.448 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 3.566203e-01 0.448 0 0
Binding and entry of HIV virion R-HSA-173107 3.570293e-01 0.447 0 0
2-LTR circle formation R-HSA-164843 3.570293e-01 0.447 0 0
Regulation of CDH11 function R-HSA-9762292 3.570293e-01 0.447 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.570293e-01 0.447 0 0
Signal attenuation R-HSA-74749 3.570293e-01 0.447 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 3.570293e-01 0.447 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 3.570293e-01 0.447 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 3.570293e-01 0.447 0 0
Tandem pore domain potassium channels R-HSA-1296346 3.570293e-01 0.447 0 0
Signaling by Leptin R-HSA-2586552 3.570293e-01 0.447 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 3.594710e-01 0.444 0 0
Calnexin/calreticulin cycle R-HSA-901042 3.626845e-01 0.440 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 3.626845e-01 0.440 0 0
Signaling by FGFR R-HSA-190236 3.633131e-01 0.440 0 0
Synthesis of DNA R-HSA-69239 3.650199e-01 0.438 0 0
Interferon alpha/beta signaling R-HSA-909733 3.663752e-01 0.436 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 3.725219e-01 0.429 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 3.725219e-01 0.429 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 3.725219e-01 0.429 0 0
Suppression of phagosomal maturation R-HSA-9637687 3.725219e-01 0.429 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 3.791616e-01 0.421 0 0
Oncogene Induced Senescence R-HSA-2559585 3.815606e-01 0.418 0 0
PKA activation R-HSA-163615 3.825754e-01 0.417 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 3.825754e-01 0.417 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 3.825754e-01 0.417 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 3.825754e-01 0.417 0 0
Presynaptic function of Kainate receptors R-HSA-500657 3.825754e-01 0.417 0 0
GAB1 signalosome R-HSA-180292 3.825754e-01 0.417 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 3.828195e-01 0.417 0 0
Axonal growth stimulation R-HSA-209563 3.828195e-01 0.417 0 0
Defective HPRT1 disrupts guanine and hypoxanthine salvage R-HSA-9734281 3.828195e-01 0.417 0 0
Defective CYP1B1 causes Glaucoma R-HSA-5579000 3.828195e-01 0.417 0 0
FasL/ CD95L signaling R-HSA-75157 3.828195e-01 0.417 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 3.828195e-01 0.417 0 0
MET interacts with TNS proteins R-HSA-8875513 3.828195e-01 0.417 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 3.828195e-01 0.417 0 0
Intracellular oxygen transport R-HSA-8981607 3.828195e-01 0.417 0 0
PECAM1 interactions R-HSA-210990 3.912071e-01 0.408 0 0
Formation of the posterior neural plate R-HSA-9832991 3.912071e-01 0.408 0 0
Chylomicron assembly R-HSA-8963888 3.912071e-01 0.408 0 0
Suppression of apoptosis R-HSA-9635465 3.912071e-01 0.408 0 0
ChREBP activates metabolic gene expression R-HSA-163765 3.912071e-01 0.408 0 0
Signaling by BMP R-HSA-201451 3.940979e-01 0.404 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 3.940979e-01 0.404 0 0
Insulin processing R-HSA-264876 3.940979e-01 0.404 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.940979e-01 0.404 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 3.940979e-01 0.404 0 0
Maturation of hRSV A proteins R-HSA-9828806 3.940979e-01 0.404 0 0
Interleukin-1 signaling R-HSA-9020702 3.977954e-01 0.400 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.977954e-01 0.400 0 0
RET signaling R-HSA-8853659 4.004141e-01 0.397 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 4.004141e-01 0.397 0 0
Triglyceride catabolism R-HSA-163560 4.004141e-01 0.397 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 4.041896e-01 0.393 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 4.041896e-01 0.393 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 4.082859e-01 0.389 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 4.082859e-01 0.389 0 0
The NLRP3 inflammasome R-HSA-844456 4.082859e-01 0.389 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 4.082859e-01 0.389 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.087458e-01 0.389 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 4.088255e-01 0.388 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 4.155549e-01 0.381 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.155549e-01 0.381 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 4.211065e-01 0.376 0 0
Signaling by FGFR1 R-HSA-5654736 4.220375e-01 0.375 0 0
NRAGE signals death through JNK R-HSA-193648 4.220375e-01 0.375 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 4.245423e-01 0.372 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.245423e-01 0.372 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.245423e-01 0.372 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.245423e-01 0.372 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 4.245423e-01 0.372 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.245423e-01 0.372 0 0
Sodium/Calcium exchangers R-HSA-425561 4.245423e-01 0.372 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 4.336617e-01 0.363 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 4.336617e-01 0.363 0 0
Signaling by NODAL R-HSA-1181150 4.336617e-01 0.363 0 0
Signaling by NTRKs R-HSA-166520 4.359938e-01 0.361 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.368365e-01 0.360 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 4.368365e-01 0.360 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 4.375058e-01 0.359 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.379584e-01 0.359 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 4.396146e-01 0.357 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 4.396146e-01 0.357 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 4.396146e-01 0.357 0 0
Signaling by MAP2K mutants R-HSA-9652169 4.396146e-01 0.357 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 4.396146e-01 0.357 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.396146e-01 0.357 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 4.396146e-01 0.357 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.396146e-01 0.357 0 0
NADE modulates death signalling R-HSA-205025 4.396146e-01 0.357 0 0
Dopamine receptors R-HSA-390651 4.396146e-01 0.357 0 0
Ion channel transport R-HSA-983712 4.474136e-01 0.349 0 0
ABC transporter disorders R-HSA-5619084 4.492688e-01 0.347 0 0
Dual incision in TC-NER R-HSA-6782135 4.529101e-01 0.344 0 0
GPER1 signaling R-HSA-9634597 4.547170e-01 0.342 0 0
RAS processing R-HSA-9648002 4.564332e-01 0.341 0 0
Signaling by ALK R-HSA-201556 4.564332e-01 0.341 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 4.567420e-01 0.340 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.569006e-01 0.340 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 4.569006e-01 0.340 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.569006e-01 0.340 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.569006e-01 0.340 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 4.569006e-01 0.340 0 0
OAS antiviral response R-HSA-8983711 4.569006e-01 0.340 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 4.578908e-01 0.339 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 4.586238e-01 0.339 0 0
G-protein activation R-HSA-202040 4.586238e-01 0.339 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 4.586238e-01 0.339 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 4.586238e-01 0.339 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 4.653526e-01 0.332 0 0
Peroxisomal protein import R-HSA-9033241 4.682291e-01 0.330 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 4.713558e-01 0.327 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 4.748024e-01 0.323 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 4.760256e-01 0.322 0 0
Downstream signal transduction R-HSA-186763 4.786706e-01 0.320 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 4.792671e-01 0.319 0 0
Ribavirin ADME R-HSA-9755088 4.831031e-01 0.316 0 0
GABA receptor activation R-HSA-977443 4.834426e-01 0.316 0 0
Protein localization R-HSA-9609507 4.839940e-01 0.315 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 4.881796e-01 0.311 0 0
Processing of SMDT1 R-HSA-8949664 4.881796e-01 0.311 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 4.881796e-01 0.311 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 4.881796e-01 0.311 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 4.881796e-01 0.311 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 4.881796e-01 0.311 0 0
Stimuli-sensing channels R-HSA-2672351 4.899385e-01 0.310 0 0
Selenoamino acid metabolism R-HSA-2408522 4.903908e-01 0.309 0 0
Trafficking of myristoylated proteins to the cilium R-HSA-5624138 4.911862e-01 0.309 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 4.911862e-01 0.309 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 4.911862e-01 0.309 0 0
G2 Phase R-HSA-68911 4.911862e-01 0.309 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 4.911862e-01 0.309 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 4.911862e-01 0.309 0 0
Defective F9 activation R-HSA-9673221 4.911862e-01 0.309 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 4.911862e-01 0.309 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 4.911862e-01 0.309 0 0
Reelin signalling pathway R-HSA-8866376 4.911862e-01 0.309 0 0
Muscarinic acetylcholine receptors R-HSA-390648 4.911862e-01 0.309 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 4.911862e-01 0.309 0 0
NrCAM interactions R-HSA-447038 4.911862e-01 0.309 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 4.911862e-01 0.309 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 4.911862e-01 0.309 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 4.911862e-01 0.309 0 0
FOXO-mediated transcription R-HSA-9614085 4.937447e-01 0.306 0 0
Mitochondrial biogenesis R-HSA-1592230 4.973456e-01 0.303 0 0
Diseases of mitotic cell cycle R-HSA-9675126 4.991332e-01 0.302 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 4.991332e-01 0.302 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 5.070406e-01 0.295 0 0
Cellular hexose transport R-HSA-189200 5.070406e-01 0.295 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 5.070406e-01 0.295 0 0
Integration of energy metabolism R-HSA-163685 5.104856e-01 0.292 0 0
Translation of Structural Proteins R-HSA-9683701 5.108886e-01 0.292 0 0
Heme signaling R-HSA-9707616 5.134769e-01 0.289 0 0
Retrograde neurotrophin signalling R-HSA-177504 5.183040e-01 0.285 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 5.183040e-01 0.285 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 5.183040e-01 0.285 0 0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA R-HSA-77310 5.183040e-01 0.285 0 0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA R-HSA-77348 5.183040e-01 0.285 0 0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA R-HSA-77350 5.183040e-01 0.285 0 0
Physiological factors R-HSA-5578768 5.183040e-01 0.285 0 0
Malate-aspartate shuttle R-HSA-9856872 5.183040e-01 0.285 0 0
Regulation of KIT signaling R-HSA-1433559 5.183040e-01 0.285 0 0
Acyl chain remodeling of CL R-HSA-1482798 5.183040e-01 0.285 0 0
G-protein beta:gamma signalling R-HSA-397795 5.192403e-01 0.285 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.192403e-01 0.285 0 0
FGFR1 mutant receptor activation R-HSA-1839124 5.192403e-01 0.285 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 5.203102e-01 0.284 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 5.203102e-01 0.284 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 5.303863e-01 0.275 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 5.303863e-01 0.275 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 5.303863e-01 0.275 0 0
Amino acids regulate mTORC1 R-HSA-9639288 5.362344e-01 0.271 0 0
Plus-strand DNA synthesis R-HSA-164525 5.380146e-01 0.269 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 5.380146e-01 0.269 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 5.380146e-01 0.269 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 5.380146e-01 0.269 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 5.380146e-01 0.269 0 0
Toxicity of botulinum toxin type E (botE) R-HSA-5250992 5.380146e-01 0.269 0 0
TRAIL signaling R-HSA-75158 5.380146e-01 0.269 0 0
Pentose phosphate pathway disease R-HSA-6791465 5.380146e-01 0.269 0 0
Cam-PDE 1 activation R-HSA-111957 5.380146e-01 0.269 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 5.380146e-01 0.269 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 5.380146e-01 0.269 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.380146e-01 0.269 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 5.380146e-01 0.269 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 5.380146e-01 0.269 0 0
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397 5.380146e-01 0.269 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 5.380146e-01 0.269 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 5.380146e-01 0.269 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 5.380146e-01 0.269 0 0
Effects of PIP2 hydrolysis R-HSA-114508 5.389581e-01 0.268 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 5.389581e-01 0.268 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 5.389581e-01 0.268 0 0
Erythropoietin activates RAS R-HSA-9027284 5.472214e-01 0.262 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.472214e-01 0.262 0 0
DNA Damage Reversal R-HSA-73942 5.472214e-01 0.262 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 5.472214e-01 0.262 0 0
Formation of the anterior neural plate R-HSA-9823739 5.472214e-01 0.262 0 0
Thromboxane signalling through TP receptor R-HSA-428930 5.530986e-01 0.257 0 0
Toll-like Receptor Cascades R-HSA-168898 5.539131e-01 0.257 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 5.541206e-01 0.256 0 0
MITF-M-dependent gene expression R-HSA-9856651 5.548255e-01 0.256 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 5.582568e-01 0.253 0 0
Proteasome assembly R-HSA-9907900 5.629815e-01 0.250 0 0
EPHB-mediated forward signaling R-HSA-3928662 5.629815e-01 0.250 0 0
G1 Phase R-HSA-69236 5.629815e-01 0.250 0 0
Cyclin D associated events in G1 R-HSA-69231 5.629815e-01 0.250 0 0
Attachment and Entry R-HSA-9678110 5.748987e-01 0.240 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.748987e-01 0.240 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.748987e-01 0.240 0 0
Chylomicron clearance R-HSA-8964026 5.805356e-01 0.236 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.805356e-01 0.236 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 5.805356e-01 0.236 0 0
Uncoating of the HIV Virion R-HSA-162585 5.805356e-01 0.236 0 0
Autointegration results in viral DNA circles R-HSA-177539 5.805356e-01 0.236 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 5.805356e-01 0.236 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 5.805356e-01 0.236 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.805356e-01 0.236 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 5.805356e-01 0.236 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 5.805356e-01 0.236 0 0
Neurofascin interactions R-HSA-447043 5.805356e-01 0.236 0 0
Abacavir transmembrane transport R-HSA-2161517 5.805356e-01 0.236 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 5.805356e-01 0.236 0 0
Metabolism of vitamin K R-HSA-6806664 5.805356e-01 0.236 0 0
CREB phosphorylation R-HSA-199920 5.805356e-01 0.236 0 0
VLDL assembly R-HSA-8866423 5.805356e-01 0.236 0 0
HDL clearance R-HSA-8964011 5.805356e-01 0.236 0 0
Signaling by TGFBR3 R-HSA-9839373 5.960934e-01 0.225 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 5.964952e-01 0.224 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 5.964952e-01 0.224 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 6.012970e-01 0.221 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 6.013194e-01 0.221 0 0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA R-HSA-77346 6.013194e-01 0.221 0 0
Coenzyme A biosynthesis R-HSA-196783 6.013194e-01 0.221 0 0
Passive transport by Aquaporins R-HSA-432047 6.013194e-01 0.221 0 0
Synthesis of PG R-HSA-1483148 6.013194e-01 0.221 0 0
Regulation of insulin secretion R-HSA-422356 6.056963e-01 0.218 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 6.056963e-01 0.218 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 6.056963e-01 0.218 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 6.056963e-01 0.218 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 6.079687e-01 0.216 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 6.120899e-01 0.213 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 6.171331e-01 0.210 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 6.187158e-01 0.209 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 6.191453e-01 0.208 0 0
IFNG signaling activates MAPKs R-HSA-9732724 6.191453e-01 0.208 0 0
Disinhibition of SNARE formation R-HSA-114516 6.191453e-01 0.208 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 6.191453e-01 0.208 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 6.191453e-01 0.208 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 6.191453e-01 0.208 0 0
LDL remodeling R-HSA-8964041 6.191453e-01 0.208 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.191453e-01 0.208 0 0
Maturation of replicase proteins R-HSA-9694301 6.191453e-01 0.208 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.263697e-01 0.203 0 0
Triglyceride metabolism R-HSA-8979227 6.264089e-01 0.203 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 6.264089e-01 0.203 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 6.264801e-01 0.203 0 0
Specification of primordial germ cells R-HSA-9827857 6.264801e-01 0.203 0 0
Uptake and function of anthrax toxins R-HSA-5210891 6.264801e-01 0.203 0 0
Co-stimulation by CD28 R-HSA-389356 6.277536e-01 0.202 0 0
Metal ion SLC transporters R-HSA-425410 6.277536e-01 0.202 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 6.306731e-01 0.200 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 6.306731e-01 0.200 0 0
Neddylation R-HSA-8951664 6.321109e-01 0.199 0 0
HIV elongation arrest and recovery R-HSA-167287 6.370433e-01 0.196 0 0
Pausing and recovery of HIV elongation R-HSA-167290 6.370433e-01 0.196 0 0
Inflammasomes R-HSA-622312 6.370433e-01 0.196 0 0
RAB geranylgeranylation R-HSA-8873719 6.404176e-01 0.194 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 6.476920e-01 0.189 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 6.476920e-01 0.189 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 6.498431e-01 0.187 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 6.499524e-01 0.187 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 6.503891e-01 0.187 0 0
Synaptic adhesion-like molecules R-HSA-8849932 6.503891e-01 0.187 0 0
Ephrin signaling R-HSA-3928664 6.503891e-01 0.187 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 6.503891e-01 0.187 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.503891e-01 0.187 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 6.505618e-01 0.187 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.520674e-01 0.186 0 0
Parasite infection R-HSA-9664407 6.520674e-01 0.186 0 0
Leishmania phagocytosis R-HSA-9664417 6.520674e-01 0.186 0 0
Formation of paraxial mesoderm R-HSA-9793380 6.541078e-01 0.184 0 0
Reverse Transcription of HIV RNA R-HSA-162589 6.542032e-01 0.184 0 0
Minus-strand DNA synthesis R-HSA-164516 6.542032e-01 0.184 0 0
RSK activation R-HSA-444257 6.542032e-01 0.184 0 0
phospho-PLA2 pathway R-HSA-111995 6.542032e-01 0.184 0 0
MET receptor recycling R-HSA-8875656 6.542032e-01 0.184 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 6.542032e-01 0.184 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 6.542032e-01 0.184 0 0
Sodium/Proton exchangers R-HSA-425986 6.542032e-01 0.184 0 0
Co-stimulation by ICOS R-HSA-9927354 6.542032e-01 0.184 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 6.542032e-01 0.184 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 6.542032e-01 0.184 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.542032e-01 0.184 0 0
Nucleotide salvage defects R-HSA-9734207 6.542032e-01 0.184 0 0
TGFBR3 PTM regulation R-HSA-9839383 6.542032e-01 0.184 0 0
Adrenoceptors R-HSA-390696 6.542032e-01 0.184 0 0
Interleukin-23 signaling R-HSA-9020933 6.542032e-01 0.184 0 0
Signaling by Erythropoietin R-HSA-9006335 6.562172e-01 0.183 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 6.562172e-01 0.183 0 0
Glucagon-type ligand receptors R-HSA-420092 6.562172e-01 0.183 0 0
Azathioprine ADME R-HSA-9748787 6.578653e-01 0.182 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 6.601716e-01 0.180 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 6.602456e-01 0.180 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 6.602456e-01 0.180 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 6.610806e-01 0.180 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 6.640617e-01 0.178 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 6.640617e-01 0.178 0 0
Diseases of Immune System R-HSA-5260271 6.640617e-01 0.178 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 6.640617e-01 0.178 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 6.643275e-01 0.178 0 0
Mitochondrial protein degradation R-HSA-9837999 6.720007e-01 0.173 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 6.730635e-01 0.172 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.730635e-01 0.172 0 0
Activation of the pre-replicative complex R-HSA-68962 6.746509e-01 0.171 0 0
DAP12 signaling R-HSA-2424491 6.746509e-01 0.171 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 6.746509e-01 0.171 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 6.799047e-01 0.168 0 0
WNT mediated activation of DVL R-HSA-201688 6.860359e-01 0.164 0 0
MAPK1 (ERK2) activation R-HSA-112411 6.860359e-01 0.164 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 6.860359e-01 0.164 0 0
Toxicity of botulinum toxin type A (botA) R-HSA-5250968 6.860359e-01 0.164 0 0
p75NTR regulates axonogenesis R-HSA-193697 6.860359e-01 0.164 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 6.860359e-01 0.164 0 0
mRNA Editing R-HSA-75072 6.860359e-01 0.164 0 0
Regulation of signaling by NODAL R-HSA-1433617 6.860359e-01 0.164 0 0
Interleukin-1 processing R-HSA-448706 6.860359e-01 0.164 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 6.860359e-01 0.164 0 0
Iron uptake and transport R-HSA-917937 6.884555e-01 0.162 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 6.895337e-01 0.161 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.945280e-01 0.158 0 0
Co-inhibition by CTLA4 R-HSA-389513 6.945280e-01 0.158 0 0
Protein hydroxylation R-HSA-9629569 6.945280e-01 0.158 0 0
Signal transduction by L1 R-HSA-445144 6.945280e-01 0.158 0 0
Formation of definitive endoderm R-HSA-9823730 6.945280e-01 0.158 0 0
HIV Transcription Initiation R-HSA-167161 6.952177e-01 0.158 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 6.952177e-01 0.158 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 6.952177e-01 0.158 0 0
Intra-Golgi traffic R-HSA-6811438 6.952177e-01 0.158 0 0
Signaling by FGFR1 in disease R-HSA-5655302 6.952177e-01 0.158 0 0
Scavenging by Class A Receptors R-HSA-3000480 6.952177e-01 0.158 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 7.034723e-01 0.153 0 0
Potassium Channels R-HSA-1296071 7.034723e-01 0.153 0 0
MTOR signalling R-HSA-165159 7.099992e-01 0.149 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 7.148132e-01 0.146 0 0
ERK/MAPK targets R-HSA-198753 7.148132e-01 0.146 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 7.148132e-01 0.146 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 7.149400e-01 0.146 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 7.149400e-01 0.146 0 0
Metabolism of serotonin R-HSA-380612 7.149400e-01 0.146 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 7.149400e-01 0.146 0 0
Receptor Mediated Mitophagy R-HSA-8934903 7.149400e-01 0.146 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 7.149400e-01 0.146 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 7.242503e-01 0.140 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.255323e-01 0.139 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 7.262134e-01 0.139 0 0
tRNA processing R-HSA-72306 7.332081e-01 0.135 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 7.339542e-01 0.134 0 0
Attachment and Entry R-HSA-9694614 7.339542e-01 0.134 0 0
Mitochondrial calcium ion transport R-HSA-8949215 7.339542e-01 0.134 0 0
Metabolism of Angiotensinogen to Angiotensins R-HSA-2022377 7.339542e-01 0.134 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 7.339542e-01 0.134 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 7.339542e-01 0.134 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 7.383874e-01 0.132 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.383874e-01 0.132 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 7.410437e-01 0.130 0 0
Ionotropic activity of kainate receptors R-HSA-451306 7.411846e-01 0.130 0 0
vRNA Synthesis R-HSA-192814 7.411846e-01 0.130 0 0
vRNP Assembly R-HSA-192905 7.411846e-01 0.130 0 0
Conjugation of benzoate with glycine R-HSA-177135 7.411846e-01 0.130 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 7.411846e-01 0.130 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 7.411846e-01 0.130 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 7.411846e-01 0.130 0 0
Dissolution of Fibrin Clot R-HSA-75205 7.411846e-01 0.130 0 0
Leishmania infection R-HSA-9658195 7.413800e-01 0.130 0 0
Parasitic Infection Pathways R-HSA-9824443 7.413800e-01 0.130 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 7.511740e-01 0.124 0 0
Somitogenesis R-HSA-9824272 7.511740e-01 0.124 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 7.519897e-01 0.124 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 7.519897e-01 0.124 0 0
LDL clearance R-HSA-8964038 7.519897e-01 0.124 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 7.519897e-01 0.124 0 0
Interleukin-1 family signaling R-HSA-446652 7.585945e-01 0.120 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 7.638571e-01 0.117 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 7.650144e-01 0.116 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 7.650144e-01 0.116 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 7.650144e-01 0.116 0 0
ERKs are inactivated R-HSA-202670 7.650144e-01 0.116 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 7.650144e-01 0.116 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 7.650144e-01 0.116 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 7.650144e-01 0.116 0 0
Activation of RAC1 R-HSA-428540 7.650144e-01 0.116 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 7.689610e-01 0.114 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 7.689610e-01 0.114 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 7.689610e-01 0.114 0 0
Mitochondrial mRNA modification R-HSA-9937008 7.689610e-01 0.114 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 7.689610e-01 0.114 0 0
Growth hormone receptor signaling R-HSA-982772 7.689610e-01 0.114 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 7.824660e-01 0.107 0 0
FCERI mediated NF-kB activation R-HSA-2871837 7.828594e-01 0.106 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 7.834061e-01 0.106 0 0
GPVI-mediated activation cascade R-HSA-114604 7.834061e-01 0.106 0 0
RNA Polymerase III Transcription R-HSA-74158 7.834061e-01 0.106 0 0
RUNX2 regulates bone development R-HSA-8941326 7.834061e-01 0.106 0 0
Collagen formation R-HSA-1474290 7.839157e-01 0.106 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 7.849111e-01 0.105 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.849111e-01 0.105 0 0
Mitochondrial RNA degradation R-HSA-9836573 7.849111e-01 0.105 0 0
Plasma lipoprotein assembly R-HSA-8963898 7.849111e-01 0.105 0 0
Complex III assembly R-HSA-9865881 7.849111e-01 0.105 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 7.866514e-01 0.104 0 0
Beta oxidation of myristoyl-CoA to lauroyl-CoA R-HSA-77285 7.866514e-01 0.104 0 0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA R-HSA-77305 7.866514e-01 0.104 0 0
Conjugation of salicylate with glycine R-HSA-177128 7.866514e-01 0.104 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 7.866514e-01 0.104 0 0
Synthesis of GDP-mannose R-HSA-446205 7.866514e-01 0.104 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 7.866514e-01 0.104 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 7.866514e-01 0.104 0 0
MET activates RAS signaling R-HSA-8851805 7.866514e-01 0.104 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 7.866514e-01 0.104 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 7.877029e-01 0.104 0 0
NGF-stimulated transcription R-HSA-9031628 7.877029e-01 0.104 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 7.881133e-01 0.103 0 0
Asparagine N-linked glycosylation R-HSA-446203 7.900031e-01 0.102 0 0
Collagen chain trimerization R-HSA-8948216 7.961909e-01 0.099 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.993036e-01 0.097 0 0
Laminin interactions R-HSA-3000157 7.998842e-01 0.097 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 7.998842e-01 0.097 0 0
Formation of the nephric duct R-HSA-9830364 7.998842e-01 0.097 0 0
Chylomicron remodeling R-HSA-8963901 8.062972e-01 0.094 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 8.062972e-01 0.094 0 0
Formation of axial mesoderm R-HSA-9796292 8.062972e-01 0.094 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 8.062972e-01 0.094 0 0
Diseases of nucleotide metabolism R-HSA-9735804 8.062972e-01 0.094 0 0
rRNA modification in the mitochondrion R-HSA-6793080 8.062972e-01 0.094 0 0
CD28 dependent Vav1 pathway R-HSA-389359 8.062972e-01 0.094 0 0
Maturation of nucleoprotein R-HSA-9683610 8.062972e-01 0.094 0 0
Interleukin-6 signaling R-HSA-1059683 8.062972e-01 0.094 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.062972e-01 0.094 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.083387e-01 0.092 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 8.103705e-01 0.091 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 8.139248e-01 0.089 0 0
Myogenesis R-HSA-525793 8.139248e-01 0.089 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 8.139248e-01 0.089 0 0
Urea cycle R-HSA-70635 8.139248e-01 0.089 0 0
Abacavir ADME R-HSA-2161522 8.139248e-01 0.089 0 0
The phototransduction cascade R-HSA-2514856 8.198144e-01 0.086 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 8.241351e-01 0.084 0 0
Removal of the Flap Intermediate R-HSA-69166 8.241351e-01 0.084 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 8.241351e-01 0.084 0 0
Hydrolysis of LPC R-HSA-1483115 8.241351e-01 0.084 0 0
Signaling by FGFR4 in disease R-HSA-5655291 8.241351e-01 0.084 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.241351e-01 0.084 0 0
Signal regulatory protein family interactions R-HSA-391160 8.241351e-01 0.084 0 0
Zinc transporters R-HSA-435354 8.241351e-01 0.084 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 8.241351e-01 0.084 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 8.250557e-01 0.084 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 8.270777e-01 0.082 0 0
Synthesis of PE R-HSA-1483213 8.270777e-01 0.082 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.308036e-01 0.081 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 8.308036e-01 0.081 0 0
Telomere Extension By Telomerase R-HSA-171319 8.393874e-01 0.076 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 8.393874e-01 0.076 0 0
Pyroptosis R-HSA-5620971 8.393874e-01 0.076 0 0
Processive synthesis on the lagging strand R-HSA-69183 8.403313e-01 0.076 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 8.403313e-01 0.076 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 8.403313e-01 0.076 0 0
Beta oxidation of butanoyl-CoA to acetyl-CoA R-HSA-77352 8.403313e-01 0.076 0 0
FASTK family proteins regulate processing and stability of mitochondrial RNAs R-HSA-9837092 8.403313e-01 0.076 0 0
Other semaphorin interactions R-HSA-416700 8.403313e-01 0.076 0 0
Signaling by Activin R-HSA-1502540 8.403313e-01 0.076 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 8.494058e-01 0.071 0 0
mRNA Capping R-HSA-72086 8.508974e-01 0.070 0 0
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) R-HSA-2142816 8.550367e-01 0.068 0 0
Phosphorylation of the APC/C R-HSA-176412 8.550367e-01 0.068 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 8.550367e-01 0.068 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 8.550367e-01 0.068 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 8.550367e-01 0.068 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 8.550367e-01 0.068 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 8.550367e-01 0.068 0 0
Killing mechanisms R-HSA-9664420 8.550367e-01 0.068 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 8.550367e-01 0.068 0 0
Activation of the phototransduction cascade R-HSA-2485179 8.550367e-01 0.068 0 0
Differentiation of T cells R-HSA-9945266 8.550367e-01 0.068 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 8.550367e-01 0.068 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 8.550367e-01 0.068 0 0
Activation of SMO R-HSA-5635838 8.550367e-01 0.068 0 0
Fructose catabolism R-HSA-70350 8.550367e-01 0.068 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 8.550367e-01 0.068 0 0
Atorvastatin ADME R-HSA-9754706 8.550367e-01 0.068 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 8.550367e-01 0.068 0 0
Virus Assembly and Release R-HSA-168268 8.550367e-01 0.068 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.602414e-01 0.065 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 8.616506e-01 0.065 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 8.616506e-01 0.065 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 8.616506e-01 0.065 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.616506e-01 0.065 0 0
Interleukin-37 signaling R-HSA-9008059 8.616506e-01 0.065 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 8.683886e-01 0.061 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 8.683886e-01 0.061 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 8.683886e-01 0.061 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 8.683886e-01 0.061 0 0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids R-HSA-77288 8.683886e-01 0.061 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 8.683886e-01 0.061 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 8.683886e-01 0.061 0 0
tRNA modification in the mitochondrion R-HSA-6787450 8.683886e-01 0.061 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 8.683886e-01 0.061 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 8.683886e-01 0.061 0 0
Signaling by SCF-KIT R-HSA-1433557 8.690043e-01 0.061 0 0
COPII-mediated vesicle transport R-HSA-204005 8.705314e-01 0.060 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.711200e-01 0.060 0 0
Cargo concentration in the ER R-HSA-5694530 8.716888e-01 0.060 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 8.729480e-01 0.059 0 0
DAP12 interactions R-HSA-2172127 8.772784e-01 0.057 0 0
Amine ligand-binding receptors R-HSA-375280 8.772784e-01 0.057 0 0
Gastrulation R-HSA-9758941 8.799355e-01 0.056 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 8.805114e-01 0.055 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 8.805114e-01 0.055 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 8.805114e-01 0.055 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 8.805114e-01 0.055 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 8.805114e-01 0.055 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 8.805114e-01 0.055 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 8.810524e-01 0.055 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 8.838028e-01 0.054 0 0
Extension of Telomeres R-HSA-180786 8.862776e-01 0.052 0 0
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) R-HSA-2142670 8.915182e-01 0.050 0 0
PKA activation in glucagon signalling R-HSA-164378 8.915182e-01 0.050 0 0
Mismatch Repair R-HSA-5358508 8.915182e-01 0.050 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 8.915182e-01 0.050 0 0
Tie2 Signaling R-HSA-210993 8.915182e-01 0.050 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 8.915182e-01 0.050 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.924451e-01 0.049 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.924451e-01 0.049 0 0
tRNA Aminoacylation R-HSA-379724 8.928641e-01 0.049 0 0
Metabolism of polyamines R-HSA-351202 8.928641e-01 0.049 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.931272e-01 0.049 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 8.948224e-01 0.048 0 0
Signaling by FGFR in disease R-HSA-1226099 8.958917e-01 0.048 0 0
Innate Immune System R-HSA-168249 8.978687e-01 0.047 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 8.979107e-01 0.047 0 0
Glutamate and glutamine metabolism R-HSA-8964539 8.979107e-01 0.047 0 0
Heme degradation R-HSA-189483 8.979107e-01 0.047 0 0
Miscellaneous transport and binding events R-HSA-5223345 8.979107e-01 0.047 0 0
Collagen degradation R-HSA-1442490 8.991134e-01 0.046 0 0
Synthesis of PC R-HSA-1483191 8.993794e-01 0.046 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 9.015117e-01 0.045 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 9.015117e-01 0.045 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 9.015117e-01 0.045 0 0
Germ layer formation at gastrulation R-HSA-9754189 9.015117e-01 0.045 0 0
Conjugation of carboxylic acids R-HSA-159424 9.015117e-01 0.045 0 0
Amino Acid conjugation R-HSA-156587 9.015117e-01 0.045 0 0
E2F mediated regulation of DNA replication R-HSA-113510 9.015117e-01 0.045 0 0
Other interleukin signaling R-HSA-449836 9.015117e-01 0.045 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.015117e-01 0.045 0 0
Methionine salvage pathway R-HSA-1237112 9.015117e-01 0.045 0 0
Diseases of hemostasis R-HSA-9671793 9.015117e-01 0.045 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.015117e-01 0.045 0 0
HDL remodeling R-HSA-8964058 9.015117e-01 0.045 0 0
Maturation of nucleoprotein R-HSA-9694631 9.015117e-01 0.045 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 9.015117e-01 0.045 0 0
SLC transporter disorders R-HSA-5619102 9.040991e-01 0.044 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.050390e-01 0.043 0 0
Signaling by PDGF R-HSA-186797 9.050390e-01 0.043 0 0
PPARA activates gene expression R-HSA-1989781 9.051092e-01 0.043 0 0
eNOS activation R-HSA-203615 9.054790e-01 0.043 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.105852e-01 0.041 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 9.105852e-01 0.041 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.105852e-01 0.041 0 0
Creatine metabolism R-HSA-71288 9.105852e-01 0.041 0 0
Translation of Structural Proteins R-HSA-9694635 9.119791e-01 0.040 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.124615e-01 0.040 0 0
Neurotransmitter release cycle R-HSA-112310 9.146979e-01 0.039 0 0
PI3K Cascade R-HSA-109704 9.178266e-01 0.037 0 0
PI Metabolism R-HSA-1483255 9.181322e-01 0.037 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 9.188232e-01 0.037 0 0
Lagging Strand Synthesis R-HSA-69186 9.188232e-01 0.037 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 9.188232e-01 0.037 0 0
Abacavir metabolism R-HSA-2161541 9.188232e-01 0.037 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.188232e-01 0.037 0 0
Interferon gamma signaling R-HSA-877300 9.193312e-01 0.037 0 0
Voltage gated Potassium channels R-HSA-1296072 9.251496e-01 0.034 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 9.263026e-01 0.033 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.263026e-01 0.033 0 0
CS-GAG biosynthesis R-HSA-2022870 9.263026e-01 0.033 0 0
Serine metabolism R-HSA-977347 9.263026e-01 0.033 0 0
Glutathione synthesis and recycling R-HSA-174403 9.263026e-01 0.033 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.273794e-01 0.033 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.291431e-01 0.032 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.307995e-01 0.031 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 9.307995e-01 0.031 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.330934e-01 0.030 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 9.330934e-01 0.030 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 9.330934e-01 0.030 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 9.330934e-01 0.030 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 9.330934e-01 0.030 0 0
Fructose metabolism R-HSA-5652084 9.330934e-01 0.030 0 0
Ethanol oxidation R-HSA-71384 9.330934e-01 0.030 0 0
Signaling by KIT in disease R-HSA-9669938 9.330934e-01 0.030 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.345197e-01 0.029 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 9.360442e-01 0.029 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.392587e-01 0.027 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 9.392587e-01 0.027 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 9.392587e-01 0.027 0 0
Interleukin receptor SHC signaling R-HSA-912526 9.392587e-01 0.027 0 0
Formation of the ureteric bud R-HSA-9830674 9.392587e-01 0.027 0 0
Synthesis of UDP-N-acetyl-glucosamine R-HSA-446210 9.392587e-01 0.027 0 0
Interleukin-20 family signaling R-HSA-8854691 9.392587e-01 0.027 0 0
HIV Transcription Elongation R-HSA-167169 9.409103e-01 0.026 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 9.409103e-01 0.026 0 0
rRNA processing in the mitochondrion R-HSA-8868766 9.409103e-01 0.026 0 0
Generation of second messenger molecules R-HSA-202433 9.409103e-01 0.026 0 0
Synthesis of dolichyl-phosphate R-HSA-446199 9.448563e-01 0.025 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 9.448563e-01 0.025 0 0
Interleukin-6 family signaling R-HSA-6783589 9.448563e-01 0.025 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 9.454231e-01 0.024 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 9.454231e-01 0.024 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 9.454231e-01 0.024 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.454281e-01 0.024 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.474568e-01 0.023 0 0
IRS-mediated signalling R-HSA-112399 9.494711e-01 0.023 0 0
Synthesis of PA R-HSA-1483166 9.494711e-01 0.023 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 9.496064e-01 0.022 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.499383e-01 0.022 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 9.499383e-01 0.022 0 0
Acyl chain remodelling of PS R-HSA-1482801 9.499383e-01 0.022 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.499383e-01 0.022 0 0
Beta-oxidation of pristanoyl-CoA R-HSA-389887 9.499383e-01 0.022 0 0
Alpha-oxidation of phytanate R-HSA-389599 9.499383e-01 0.022 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.499383e-01 0.022 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.509102e-01 0.022 0 0
Linoleic acid (LA) metabolism R-HSA-2046105 9.545523e-01 0.020 0 0
MET activates PTK2 signaling R-HSA-8874081 9.545523e-01 0.020 0 0
Attachment of bacteria to epithelial cells R-HSA-9638630 9.545523e-01 0.020 0 0
Sphingolipid catabolism R-HSA-9845614 9.545523e-01 0.020 0 0
Formation of the cornified envelope R-HSA-6809371 9.549340e-01 0.020 0 0
Regulation of beta-cell development R-HSA-186712 9.561654e-01 0.019 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.570725e-01 0.019 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 9.587412e-01 0.018 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 9.587412e-01 0.018 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.587412e-01 0.018 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 9.587412e-01 0.018 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.587412e-01 0.018 0 0
Triglyceride biosynthesis R-HSA-75109 9.587412e-01 0.018 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 9.587412e-01 0.018 0 0
Netrin-1 signaling R-HSA-373752 9.603962e-01 0.018 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.620218e-01 0.017 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 9.625443e-01 0.017 0 0
Formation of the Early Elongation Complex R-HSA-113418 9.625443e-01 0.017 0 0
Prednisone ADME R-HSA-9757110 9.625443e-01 0.017 0 0
mitochondrial fatty acid beta-oxidation of saturated fatty acids R-HSA-77286 9.634722e-01 0.016 0 0
Mitochondrial protein import R-HSA-1268020 9.646662e-01 0.016 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.646662e-01 0.016 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 9.659970e-01 0.015 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.659970e-01 0.015 0 0
Peptide hormone metabolism R-HSA-2980736 9.686294e-01 0.014 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.689495e-01 0.014 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 9.691317e-01 0.014 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 9.691317e-01 0.014 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.691317e-01 0.014 0 0
Neurotransmitter clearance R-HSA-112311 9.691317e-01 0.014 0 0
IGF1R signaling cascade R-HSA-2428924 9.694428e-01 0.013 0 0
Insulin receptor signalling cascade R-HSA-74751 9.694428e-01 0.013 0 0
Extracellular matrix organization R-HSA-1474244 9.696956e-01 0.013 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.713824e-01 0.013 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.715955e-01 0.013 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.719775e-01 0.012 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.719775e-01 0.012 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.719775e-01 0.012 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.736308e-01 0.012 0 0
DNA strand elongation R-HSA-69190 9.745611e-01 0.011 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.757081e-01 0.011 0 0
Cardiogenesis R-HSA-9733709 9.769067e-01 0.010 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.769067e-01 0.010 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.790361e-01 0.009 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 9.790361e-01 0.009 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.803674e-01 0.009 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.807524e-01 0.008 0 0
RA biosynthesis pathway R-HSA-5365859 9.809693e-01 0.008 0 0
Nucleotide biosynthesis R-HSA-8956320 9.810332e-01 0.008 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.827243e-01 0.008 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.827243e-01 0.008 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.827243e-01 0.008 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.843175e-01 0.007 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.843175e-01 0.007 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 9.852180e-01 0.006 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.857639e-01 0.006 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.857639e-01 0.006 0 0
Dectin-2 family R-HSA-5621480 9.864018e-01 0.006 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.865156e-01 0.006 0 0
tRNA processing in the mitochondrion R-HSA-6785470 9.870770e-01 0.006 0 0
Elastic fibre formation R-HSA-1566948 9.870770e-01 0.006 0 0
Biofilm formation R-HSA-9931953 9.870770e-01 0.006 0 0
Purine salvage R-HSA-74217 9.870770e-01 0.006 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.871041e-01 0.006 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.882691e-01 0.005 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.883201e-01 0.005 0 0
Integrin cell surface interactions R-HSA-216083 9.892665e-01 0.005 0 0
Interleukin-2 family signaling R-HSA-451927 9.893512e-01 0.005 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.912254e-01 0.004 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.912826e-01 0.004 0 0
Complex I biogenesis R-HSA-6799198 9.917893e-01 0.004 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.920350e-01 0.003 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.924558e-01 0.003 0 0
Pyrimidine catabolism R-HSA-73621 9.927699e-01 0.003 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.932376e-01 0.003 0 0
Surfactant metabolism R-HSA-5683826 9.934371e-01 0.003 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.936338e-01 0.003 0 0
Kidney development R-HSA-9830369 9.941532e-01 0.003 0 0
Nicotinate metabolism R-HSA-196807 9.941532e-01 0.003 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.945897e-01 0.002 0 0
O-linked glycosylation of mucins R-HSA-913709 9.946310e-01 0.002 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.950413e-01 0.002 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.950413e-01 0.002 0 0
ECM proteoglycans R-HSA-3000178 9.958460e-01 0.002 0 0
Metabolism of porphyrins R-HSA-189445 9.958460e-01 0.002 0 0
Metabolism of cofactors R-HSA-8978934 9.958460e-01 0.002 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.960893e-01 0.002 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.963291e-01 0.002 0 0
Signaling by Insulin receptor R-HSA-74752 9.969154e-01 0.001 0 0
G alpha (i) signalling events R-HSA-418594 9.977203e-01 0.001 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.977274e-01 0.001 0 0
Paracetamol ADME R-HSA-9753281 9.977384e-01 0.001 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.977384e-01 0.001 0 0
G alpha (s) signalling events R-HSA-418555 9.977672e-01 0.001 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.979160e-01 0.001 0 0
Mitochondrial translation elongation R-HSA-5389840 9.979296e-01 0.001 0 0
Mitochondrial translation initiation R-HSA-5368286 9.982367e-01 0.001 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.982482e-01 0.001 0 0
G alpha (q) signalling events R-HSA-416476 9.983333e-01 0.001 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.984650e-01 0.001 0 0
Phospholipid metabolism R-HSA-1483257 9.985470e-01 0.001 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.986068e-01 0.001 0 0
Glutathione conjugation R-HSA-156590 9.986068e-01 0.001 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.986068e-01 0.001 0 0
Endogenous sterols R-HSA-211976 9.987355e-01 0.001 0 0
Nucleotide salvage R-HSA-8956321 9.987355e-01 0.001 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.988225e-01 0.001 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.992087e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.992931e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.992931e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.993346e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.994716e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.994800e-01 0.000 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.995204e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.995204e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.995647e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.995693e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.995948e-01 0.000 0 0
Aspirin ADME R-HSA-9749641 9.996050e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.996392e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.996764e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.997188e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.997525e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.997568e-01 0.000 0 0
Cholesterol biosynthesis R-HSA-191273 9.997568e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.997793e-01 0.000 0 0
Keratinization R-HSA-6805567 9.997906e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.998170e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.998218e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.998573e-01 0.000 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.998737e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.998985e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999164e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999211e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999238e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999491e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999614e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999755e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999870e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999893e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999893e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999901e-01 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 9.999931e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999948e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.999963e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999965e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999983e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999991e-01 0.000 0 0
Infection with Enterobacteria R-HSA-9640148 9.999992e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999995e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999999e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999999e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999999e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999999e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways