NEK7
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0A2R8Y4L2 | S95 | Sugiyama | HNRNPA1L3 HNRNPA1P48 | RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED |
| A0MZ66 | S444 | Sugiyama | SHTN1 KIAA1598 | RPVNQTARPKTKPESSKGCEsAVDELKGILGtLNKSTSSRs |
| A0MZ66 | S473 | Sugiyama | SHTN1 KIAA1598 | LGtLNKSTSSRsLKsLDPENsEtELERILRRRKVtAEADss |
| A5A3E0 | S1065 | Sugiyama | POTEF A26C1B | ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________ |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | S939 | Sugiyama | POTEF A26C1B | VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE |
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| A5A3E0 | Y1062 | Sugiyama | POTEF A26C1B | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______ |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| A6NKT7 | S1006 | Sugiyama | RGPD3 RGP3 | FGKKDLNFKGFSGAGEKLFSsQYGKMANKANtsGDFEKDDD |
| A6NMY6 | S134 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD |
| A6NMY6 | S164 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGS |
| A6NMY6 | T163 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG |
| O00115 | S57 | Sugiyama | DNASE2 DNASE2A DNL2 | ALRGSGEAAQRGLQYKyLDEssGGWRDGRALINsPEGAVGR |
| O00170 | S53 | Sugiyama | AIP XAP2 | KATFHYRtLHsDDEGtVLDDsRARGKPMELIIGKKFKLPVW |
| O00273 | S302 | Sugiyama | DFFA DFF1 DFF45 H13 | TETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDLQN |
| O00273 | T300 | Sugiyama | DFFA DFF1 DFF45 H13 | KKTETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDL |
| O00567 | S151 | Sugiyama | NOP56 NOL5A | NLVKGLTDLSACKAQLGLGHsYSRAKVKFNVNRVDNMIIQS |
| O14737 | S51 | Sugiyama | PDCD5 TFAR19 | EAKHREAEMRNsILAQVLDQsARARLsNLALVKPEKTKAVE |
| O14818 | T152 | Sugiyama | PSMA7 HSPC | LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL |
| O15013 | S1287 | Sugiyama | ARHGEF10 KIAA0294 | WLGDSLGSMTQKsDLssssGsLsLsHGsssLEHRSEDsTIy |
| O15013 | S1289 | Sugiyama | ARHGEF10 KIAA0294 | GDSLGSMTQKsDLssssGsLsLsHGsssLEHRSEDsTIyDL |
| O15013 | S1291 | Sugiyama | ARHGEF10 KIAA0294 | SLGSMTQKsDLssssGsLsLsHGsssLEHRSEDsTIyDLLK |
| O15067 | S225 | Sugiyama | PFAS KIAA0361 | KRFQELQRNPstVEAFDLAQsNsEHSRHWFFKGQLHVDGQK |
| O15212 | S53 | Sugiyama | PFDN6 HKE2 PFD6 | LEAQLtENNIVKEELALLDGsNVVFKLLGPVLVKQELGEAR |
| O15371 | S324 | Sugiyama | EIF3D EIF3S7 | NsFNsPRNLAMEAtyINHNFsQQCLRMGKERYNFPNPNPFV |
| O15371 | Y318 | Sugiyama | EIF3D EIF3S7 | PPQDEGNsFNsPRNLAMEAtyINHNFsQQCLRMGKERYNFP |
| O15446 | S64 | Sugiyama | POLR1G ASE1 CAST CD3EAP PAF49 | LIQAPADFAPECFNGRHVPLsGsQIVKGKLAGKRHRyRVLS |
| O43164 | S196 | Sugiyama | PJA2 KIAA0438 RNF131 | EDNDHLQLSAEVVEGSRYQEsLGNtVFELENREAEAYtGLs |
| O43175 | S287 | Sugiyama | PHGDH PGDH3 | PRDRALVDHENVIsCPHLGAsTKEAQSRCGEEIAVQFVDMV |
| O43242 | S450 | Sugiyama | PSMD3 | sPEDAEFIVAKAIRDGVIEAsINHEKGYVQSKEMIDIYSTR |
| O43390 | T141 | Sugiyama | HNRNPR HNRPR | GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP |
| O43390 | Y136 | Sugiyama | HNRNPR HNRPR | QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY |
| O43615 | S94 | Sugiyama | TIMM44 MIMT44 TIM44 | NKEMKESIKKFRDEARRLEEsDVLQEARRKyKtIESETVRT |
| O43615 | T198 | Sugiyama | TIMM44 MIMT44 TIM44 | ALsQGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEFAGDKF |
| O43707 | S909 | Sugiyama | ACTN4 | PDAVPGALDyKsFStALyGEsDL__________________ |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60271 | S190 | Sugiyama | SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 | YMEHLERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLP |
| O60343 | S304 | Sugiyama | TBC1D4 AS160 KIAA0603 | ASQPALTSSRVCFPERILEDsGFDEQQEFRsRCssVTGVQR |
| O60361 | S84 | Sugiyama | NME2P1 | EGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHG |
| O60361 | T79 | Sugiyama | NME2P1 | VAMVWEGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGR |
| O60506 | T138 | Sugiyama | SYNCRIP HNRPQ NSAP1 | GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP |
| O60506 | Y133 | Sugiyama | SYNCRIP HNRPQ NSAP1 | ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY |
| O60566 | T608 | Sugiyama | BUB1B BUBR1 MAD3L SSK1 | SEDAIITGFRNVtICPNPEDtCDFARAARFVStPFHEIMSL |
| O60749 | S354 | Sugiyama | SNX2 TRG9 | RKELSANTAAFAKSAAMLGNsEDHTALSRALsQLAEVEEKI |
| O60763 | S881 | Sugiyama | USO1 VDP | KNEIKALSEERTAIKEQLDssNsTIAILQTEKDKLELEITD |
| O60841 | S196 | Sugiyama | EIF5B IF2 KIAA0741 | ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN |
| O75116 | T567 | Sugiyama | ROCK2 KIAA0619 | NQNSQISTEKVNQLQRQLDEtNALLRtESDTAARLRKTQAE |
| O75179 | S1159 | Sugiyama | ANKRD17 GTAR KIAA0697 | GADIEAQSERTKDTPLSLACsGGRQEVVELLLARGANKEHR |
| O75347 | S103 | Sugiyama | TBCA | ENEKDLEEAEEyKEARLVLDsVKLEA_______________ |
| O75436 | T102 | Sugiyama | VPS26A VPS26 | KSNTHEFVNLVKELALPGELtQSRSYDFEFMQVEKPYESYI |
| O75534 | S782 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | LDDAsAPRLMVLRQPRGPDNsMGFGAERKIRQAGVID____ |
| O75663 | S94 | Sugiyama | TIPRL | RCVNNyQGMLKVACAEEWQEsRtEGEHSKEVIKPyDWTyTT |
| O75663 | T96 | Sugiyama | TIPRL | VNNyQGMLKVACAEEWQEsRtEGEHSKEVIKPyDWTyTTDY |
| O75694 | S1232 | Sugiyama | NUP155 KIAA0791 | SDPILVQTLWQDIIEKELSDsVTLSSSDRMHALSLKIVLLG |
| O75717 | S367 | Sugiyama | WDHD1 AND1 | PsFsKGIINDDEDDEDLMMAsGRPRQRsHILEDDENsVDIs |
| O75821 | S189 | Sugiyama | EIF3G EIF3S4 | CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK |
| O76094 | S524 | Sugiyama | SRP72 | KHLPSSDSMSLKVDVEALENsAGAtyIRKKGGKVTGDsQPK |
| O94888 | S288 | Sugiyama | UBXN7 KIAA0794 UBXD7 | sssPPKKCARsEsLIDAsEDsQLEAAIRASLQETHFDstQT |
| O95218 | S181 | Sugiyama | ZRANB2 ZIS ZNF265 | DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR |
| O95218 | S188 | Sugiyama | ZRANB2 ZIS ZNF265 | KLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRRSRSKSRS |
| O95757 | S587 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM |
| O95757 | S599 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND |
| O95816 | S208 | Sugiyama | BAG2 | IKLLEHSKGAGSKTLQQNAEsRFN_________________ |
| O95816 | S31 | Sugiyama | BAG2 | NEGRFCRsssMADRsSRLLEsLDQLELRVEALREAATAVEQ |
| O95831 | T188 | Sugiyama | AIFM1 AIF PDCD8 | LPYMRPPLSKELWFSDDPNVtKtLRFKQWNGKERSIYFQPP |
| P00338 | S105 | Sugiyama | LDHA PIG19 | VTANsKLVIItAGARQQEGEsRLNLVQRNVNIFKFIIPNVV |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P00338 | T322 | Sugiyama | LDHA PIG19 | DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________ |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | T168 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF |
| P00558 | Y161 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL |
| P00966 | S131 | Sugiyama | ASS1 ASS | AKYVSHGATGKGNDQVRFELsCysLAPQIKVIAPWRMPEFY |
| P00966 | S134 | Sugiyama | ASS1 ASS | VSHGATGKGNDQVRFELsCysLAPQIKVIAPWRMPEFYNRF |
| P02545 | S525 | Sugiyama | LMNA LMN1 | tHsPPTDLVWKAQNtWGCGNsLRtALINstGEEVAMRKLVR |
| P02786 | S151 | Sugiyama | TFRC | LsEKLDstDFTGtIKLLNENsyVPREAGsQKDENLALyVEN |
| P04040 | S515 | Sugiyama | CAT | ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________ |
| P04040 | S517 | Sugiyama | CAT | LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________ |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | T49 | Sugiyama | ALDOA ALDA | GILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDR |
| P04083 | S173 | Sugiyama | ANXA1 ANX1 LPC1 | NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG |
| P04083 | S189 | Sugiyama | ANXA1 ANX1 LPC1 | tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA |
| P04083 | S201 | Sugiyama | ANXA1 ANX1 LPC1 | LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF |
| P04083 | T169 | Sugiyama | ANXA1 ANX1 LPC1 | IRDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRs |
| P04150 | S125 | Sugiyama | NR3C1 GRL | PQQGQISLSSGETDLKLLEEsIANLNRstsVPENPKSSAST |
| P04406 | S151 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T211 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P04920 | S65 | Sugiyama | SLC4A2 AE2 EPB3L1 HKB3 MPB3L | ERFEEILQEAGsRGGEEPGRsYGEEDFEyHRQSSHHIHHPL |
| P05198 | S219 | Sugiyama | EIF2S1 EIF2A | CYGYEGIDAVKEALRAGLNCsTENMPIKINLIAPPRYVMTT |
| P05362 | S444 | Sugiyama | ICAM1 | NPLPELKCLKDGtFPLPIGEsVtVtRDLEGtyLCRARSTQG |
| P05362 | S51 | Sugiyama | ICAM1 | VSPSKVILPRGGsVLVTCstsCDQPKLLGIETPLPKKELLL |
| P05362 | T448 | Sugiyama | ICAM1 | ELKCLKDGtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTR |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05455 | S325 | Sugiyama | SSB | VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA |
| P05783 | S323 | Sugiyama | KRT18 CYK18 PIG46 | VQsLEIDLDsMRNLKAsLENsLREVEARYALQMEQLNGILL |
| P05783 | S398 | Sugiyama | KRT18 CYK18 PIG46 | ATYRRLLEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKV |
| P05787 | S410 | Sugiyama | KRT8 CYK8 | TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL |
| P06733 | S14 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA |
| P06733 | S268 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S291 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA |
| P06733 | S349 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV |
| P06733 | S353 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs |
| P06733 | S40 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK |
| P06733 | T100 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | T55 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP |
| P06733 | Y270 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV |
| P06733 | Y44 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK |
| P06748 | S137 | Sugiyama | NPM1 NPM | VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK |
| P07195 | S106 | Sugiyama | LDHB | VtANSKIVVVtAGVRQQEGEsRLNLVQRNVNVFKFIIPQIV |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | S44 | Sugiyama | LDHB | ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07205 | T168 | Sugiyama | PGK2 PGKB | EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF |
| P07205 | Y161 | Sugiyama | PGK2 PGKB | KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL |
| P07237 | S88 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG |
| P07355 | S134 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD |
| P07355 | S164 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGs |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07355 | T163 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG |
| P07437 | S75 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| P07437 | T55 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs |
| P07437 | T72 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| P07737 | S85 | Sugiyama | PFN1 | tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK |
| P07737 | T65 | Sugiyama | PFN1 | PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs |
| P07814 | S1511 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PGAKCVCGKNPAKyytLFGRsy___________________ |
| P07814 | S335 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt |
| P07814 | S882 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | AQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAK |
| P07814 | T1506 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | LCELQPGAKCVCGKNPAKyytLFGRsy______________ |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S164 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGT |
| P07900 | S165 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK |
| P07900 | S399 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK |
| P07900 | S406 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | RGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKKCLELFtE |
| P07900 | S468 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | GIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQ |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S641 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD |
| P08195 | S253 | Sugiyama | SLC3A2 MDU1 | FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA |
| P08195 | S296 | Sugiyama | SLC3A2 MDU1 | DLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNYRGEN |
| P08195 | S402 | Sugiyama | SLC3A2 MDU1 | SSDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQY |
| P08195 | S403 | Sugiyama | SLC3A2 MDU1 | SDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYL |
| P08195 | S408 | Sugiyama | SLC3A2 MDU1 | ILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGN |
| P08195 | Y404 | Sugiyama | SLC3A2 MDU1 | DLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLN |
| P08238 | S159 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | VAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGT |
| P08238 | S160 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK |
| P08238 | S391 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK |
| P08238 | S398 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKKCLELFsE |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | T616 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE |
| P08238 | Y457 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK |
| P08865 | S75 | Sugiyama | RPSA LAMBR LAMR1 | WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG |
| P08865 | S79 | Sugiyama | RPSA LAMBR LAMR1 | LLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPI |
| P09104 | S40 | Sugiyama | ENO2 | VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09104 | Y44 | Sugiyama | ENO2 | LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK |
| P09211 | S66 | Sugiyama | GSTP1 FAEES3 GST3 | ASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQE |
| P09211 | T62 | Sugiyama | GSTP1 FAEES3 GST3 | GsLKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGK |
| P09211 | Y64 | Sugiyama | GSTP1 FAEES3 GST3 | LKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQ |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P09417 | S163 | Sugiyama | QDPR DHPR SDR33C1 | GTPGMIGYGMAKGAVHQLCQsLAGKNSGMPPGAAAIAVLPV |
| P09429 | S35 | Sugiyama | HMGB1 HMG1 | syAFFVQtCREEHKKKHPDAsVNFsEFsKKCsERWKtMsAK |
| P09622 | S502 | Sugiyama | DLD GCSL LAD PHE3 | RVCHAHPTLSEAFREANLAAsFGKSINF_____________ |
| P09651 | S95 | Sugiyama | HNRNPA1 HNRPA1 | RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| P09661 | S226 | Sugiyama | SNRPA1 | NAIANAstLAEVERLKGLLQsGQIPGRERRsGPtDDGEEEM |
| P09960 | S581 | Sugiyama | LTA4H LTA4 | EQGRMKFTRPLFKDLAAFDKsHDQAVRTYQEHKASMHPVTA |
| P09972 | S36 | Sugiyama | ALDOC ALDC | LsDIALRIVAPGKGILAADEsVGsMAKRLsQIGVENtEENR |
| P0CG38 | S1065 | Sugiyama | POTEI | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG38 | Y1062 | Sugiyama | POTEI | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P0CG39 | S1028 | Sugiyama | POTEJ | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | Y1025 | Sugiyama | POTEJ | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P0CG41 | S140 | Sugiyama | CTAGE8 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | T41 | Sugiyama | TUBA3C TUBA2 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| P0DPH7 | T56 | Sugiyama | TUBA3C TUBA2 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| P10412 | S55 | Sugiyama | H1-4 H1F4 HIST1H1E | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P10809 | S453 | Sugiyama | HSPD1 HSP60 | EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK |
| P10809 | S488 | Sugiyama | HSPD1 HSP60 | IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG |
| P10809 | T428 | Sugiyama | HSPD1 HSP60 | GtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGCALLRCI |
| P11142 | S153 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | AyLGKtVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNVLRII |
| P11142 | S329 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | LFRGtLDPVEKALRDAKLDKsQIHDIVLVGGstRIPKIQKL |
| P11142 | S340 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN |
| P11142 | S362 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | RIPKIQKLLQDFFNGKELNKsINPDEAVAyGAAVQAAILsG |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11142 | T45 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN |
| P11142 | T47 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P11717 | S1382 | Sugiyama | IGF2R MPRI | PPFDLTECSFKDGAGNsFDLsSLSRYSDNWEAITGTGDPEH |
| P11940 | T191 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | GRFKSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLF |
| P11940 | Y194 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF |
| P12004 | S152 | Sugiyama | PCNA | EySCVVKMPSGEFARICRDLsHIGDAVVIsCAKDGVKFSAs |
| P12004 | S161 | Sugiyama | PCNA | SGEFARICRDLsHIGDAVVIsCAKDGVKFSAsGELGNGNIK |
| P12004 | S172 | Sugiyama | PCNA | sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE |
| P12270 | S1185 | Sugiyama | TPR | KLSDKVVASVKEGVQGPLNVsLsEEGKSQEQILEILRFIRR |
| P12270 | S1241 | Sugiyama | TPR | SLRYRQRVELLERELQELQDsLNAEREKVQVTAKTMAQHEE |
| P12277 | S164 | Sugiyama | CKB CKBB | PHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAEQ |
| P13489 | S178 | Sugiyama | RNH1 PRI RNH | SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP |
| P13489 | S290 | Sugiyama | RNH1 PRI RNH | AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S38 | Sugiyama | EEF2 EF2 | NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD |
| P13639 | S587 | Sugiyama | EEF2 EF2 | CIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKAR |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13667 | S135 | Sugiyama | PDIA4 ERP70 ERP72 | IPVAKIDAtsAsVLAsRFDVsGyPtIKILKKGQAVDyEGsR |
| P13667 | S154 | Sugiyama | PDIA4 ERP70 ERP72 | VsGyPtIKILKKGQAVDyEGsRtQEEIVAKVREVSQPDWTP |
| P13667 | S379 | Sugiyama | PDIA4 ERP70 ERP72 | QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH |
| P13667 | S470 | Sugiyama | PDIA4 ERP70 ERP72 | FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP |
| P13667 | S482 | Sugiyama | PDIA4 ERP70 ERP72 | VKDLGLsEsGEDVNAAILDEsGKKFAMEPEEFDsDtLREFV |
| P13667 | T156 | Sugiyama | PDIA4 ERP70 ERP72 | GyPtIKILKKGQAVDyEGsRtQEEIVAKVREVSQPDWTPPP |
| P13674 | T140 | Sugiyama | P4HA1 P4HA | YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS |
| P13674 | T147 | Sugiyama | P4HA1 P4HA | QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC |
| P13674 | Y141 | Sugiyama | P4HA1 P4HA | FPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSF |
| P13798 | S185 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | VAEKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQ |
| P13798 | S299 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | RSALYYVDLIGGKCELLSDDsLAVssPRLSPDQCRIVYLQY |
| P13798 | S303 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | YYVDLIGGKCELLSDDsLAVssPRLSPDQCRIVYLQYPSLI |
| P13929 | S40 | Sugiyama | ENO3 | VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P13929 | Y44 | Sugiyama | ENO3 | LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK |
| P14314 | S478 | Sugiyama | PRKCSH G19P1 | DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS |
| P14314 | T134 | Sugiyama | PRKCSH G19P1 | NtCKEKGRKEREsLQQMAEVtREGFRLKKILIEDWKKAREE |
| P14314 | T469 | Sugiyama | PRKCSH G19P1 | WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt |
| P14314 | T479 | Sugiyama | PRKCSH G19P1 | KFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPSR |
| P14618 | S100 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | tHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGPEIR |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S55 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | IDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMNVARLN |
| P14618 | S77 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs |
| P14618 | S97 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP |
| P14618 | T87 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | S447 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | PKyLNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRK |
| P14625 | S515 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ |
| P14625 | S551 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKEKQDKIyFMAGsSRKEAEssPFVERLLKKGyEVIyLTEP |
| P14625 | S64 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR |
| P14625 | S674 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | WsGNMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLI |
| P14625 | T450 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | LNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRKTLD |
| P14625 | Y527 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | AKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAGsSRK |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P15153 | S158 | Sugiyama | RAC2 | TYPQGLALAKEIDSVKyLECsALtQRGLKtVFDEAIRAVLC |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15374 | S126 | Sugiyama | UCHL3 | NNKDKMHFESGSTLKKFLEEsVsMsPEERARyLENyDAIRV |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15531 | S99 | Sugiyama | NME1 NDPKA NM23 | EGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHG |
| P15531 | T94 | Sugiyama | NME1 NDPKA NM23 | VAMVWEGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGR |
| P15880 | T232 | Sugiyama | RPS2 RPS4 | KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt |
| P15924 | S1259 | Sugiyama | DSP | LDRLSRENRDLKDEIVRLNDsILQATEQRRRAEENALQQKA |
| P16333 | S320 | Sugiyama | NCK1 NCK | GHEGDFLIRDSEssPNDFSVsLKAQGKNKHFKVQLKETVYC |
| P16402 | S56 | Sugiyama | H1-3 H1F3 HIST1H1D | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P16403 | S55 | Sugiyama | H1-2 H1F2 HIST1H1C | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17066 | T228 | Sugiyama | HSPA6 HSP70B' | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P17066 | T47 | Sugiyama | HSPA6 HSP70B' | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P17066 | T49 | Sugiyama | HSPA6 HSP70B' | EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV |
| P17987 | S35 | Sugiyama | TCP1 CCT1 CCTA | EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT |
| P18615 | S135 | Sugiyama | NELFE RD RDBP | sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG |
| P18754 | S85 | Sugiyama | RCC1 CHC1 | IPEDVVQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsV |
| P19338 | S328 | Sugiyama | NCL | NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK |
| P19338 | S458 | Sugiyama | NCL | TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P19338 | S591 | Sugiyama | NCL | SKTLFVKGLsEDttEEtLKEsFDGsVRARIVTDRETGssKG |
| P19338 | S595 | Sugiyama | NCL | FVKGLsEDttEEtLKEsFDGsVRARIVTDRETGssKGFGFV |
| P19338 | Y462 | Sugiyama | NCL | AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs |
| P20073 | S216 | Sugiyama | ANXA7 ANX7 SNX OK/SW-cl.95 | KAMKGFGtDEQAIVDVVANRsNDQRQKIKAAFKTSYGKDLI |
| P20618 | Y158 | Sugiyama | PSMB1 PSC5 | IGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLD |
| P22061 | S119 | Sugiyama | PCMT1 | MVGCTGKVIGIDHIKELVDDsVNNVRKDDPTLLssGRVQLV |
| P22102 | S106 | Sugiyama | GART PGFT PRGS | LRsAGVQCFGPTAEAAQLEssKRFAKEFMDRHGIPTAQWKA |
| P22392 | S99 | Sugiyama | NME2 NM23B | EGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHG |
| P22392 | T94 | Sugiyama | NME2 NM23B | VAMVWEGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGR |
| P22626 | S225 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN |
| P22626 | S318 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GNYNDFGNYNQQPSNYGPMKsGNFGGsRNMGGPyGGGNyGP |
| P22626 | S324 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GNYNQQPSNYGPMKsGNFGGsRNMGGPyGGGNyGPGGsGGs |
| P22692 | S255 | Sugiyama | IGFBP4 IBP4 | VKLPGGLEPKGELDCHQLADsFRE_________________ |
| P23246 | S283 | Sugiyama | SFPQ PSF | GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN |
| P23381 | S357 | Sugiyama | WARS1 IFI53 WARS WRS | STFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAF |
| P23381 | S358 | Sugiyama | WARS1 IFI53 WARS WRS | TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs |
| P23381 | T364 | Sugiyama | WARS1 IFI53 WARS WRS | QGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRDtI |
| P23526 | S183 | Sugiyama | AHCY SAHH | NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI |
| P23528 | T63 | Sugiyama | CFL1 CFL | DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA |
| P23588 | S122 | Sugiyama | EIF4B | NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA |
| P24752 | S218 | Sugiyama | ACAT1 ACAT MAT | ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV |
| P25205 | S34 | Sugiyama | MCM3 | EAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVNDL |
| P25705 | S65 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | KtGtAEMssILEERILGADtsVDLEETGRVLsIGDGIARVH |
| P25786 | T11 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ |
| P26038 | S576 | Sugiyama | MSN | YKtLRQIRQGNTKQRIDEFEsM___________________ |
| P26232 | S667 | Sugiyama | CTNNA2 CAPR | YDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEEKAKIAEQV |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | T148 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV |
| P26373 | T151 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE |
| P26639 | S522 | Sugiyama | TARS1 TARS | PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP |
| P26641 | T287 | Sugiyama | EEF1G EF1G PRO1608 | EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL |
| P27348 | S145 | Sugiyama | YWHAQ | YFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHP |
| P27348 | S156 | Sugiyama | YWHAQ | DDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLGLALNFSV |
| P27348 | S37 | Sugiyama | YWHAQ | ERyDDMAtCMKAVtEQGAELsNEERNLLsVAyKNVVGGRRS |
| P27348 | S45 | Sugiyama | YWHAQ | CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI |
| P27695 | S135 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | SHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDEEHDQEG |
| P27695 | S66 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | EDPPDQKtsPsGKPAtLKICsWNVDGLRAWIKKKGLDWVKE |
| P27695 | T97 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | KKKGLDWVKEEAPDILCLQEtKCSENKLPAELQELPGLSHQ |
| P27695 | Y128 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | LQELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGD |
| P27797 | S35 | Sugiyama | CALR CRTC | AVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGK |
| P27797 | S40 | Sugiyama | CALR CRTC | AVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGKFyGDE |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | S53 | Sugiyama | CALR CRTC | WtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDAR |
| P27797 | S78 | Sugiyama | CALR CRTC | GDEEKDKGLQTSQDARFyALsAsFEPFSNKGQTLVVQFTVK |
| P27797 | S80 | Sugiyama | CALR CRTC | EEKDKGLQTSQDARFyALsAsFEPFSNKGQTLVVQFTVKHE |
| P27824 | S74 | Sugiyama | CANX | SSPKVTYKAPVPtGEVyFADsFDRGTLSGWILSKAKKDDTD |
| P28838 | S180 | Sugiyama | LAP3 LAPEP PEPS | YEYDDLKQKKKMAVSAKLyGsGDQEAWQKGVLFAsGQNLAR |
| P28838 | S194 | Sugiyama | LAP3 LAPEP PEPS | SAKLyGsGDQEAWQKGVLFAsGQNLARQLMETPANEMTPtR |
| P29144 | S1039 | Sugiyama | TPP2 | EEFTEALRDLKIQWMTKLDSsDIyNELKEtyPNyLPLyVAR |
| P29144 | S221 | Sugiyama | TPP2 | HDGEVWRACIDSNEDGDLSKsTVLRNYKEAQEYGSFGTAEM |
| P29144 | S93 | Sugiyama | TPP2 | SGDVNTATEVEPKDGEIVGLsGRVLKIPASWTNPSGKYHIG |
| P29401 | S190 | Sugiyama | TKT | ASIYKLDNLVAILDINRLGQsDPAPLQHQMDIyQKRCEAFG |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S64 | Sugiyama | EEF1D EF1D | sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI |
| P29692 | S65 | Sugiyama | EEF1D EF1D | VILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRIA |
| P29692 | T147 | Sugiyama | EEF1D EF1D | PQtQHVsPMRQVEPPAKKPAtPAEDDEDDDIDLFGsDNEEE |
| P30044 | S205 | Sugiyama | PRDX5 ACR1 SBBI10 | VQDGIVKALNVEPDGTGLTCsLAPNIISQL___________ |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30101 | S155 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | ASVPLRTEEEFKKFISDKDAsIVGFFDDsFsEAHsEFLKAA |
| P30101 | S163 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | EEFKKFISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYR |
| P30101 | T437 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KELGEKLsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsP |
| P30740 | S281 | Sugiyama | SERPINB1 ELANH2 MNEI PI2 | PENLDFIEVNVSLPRFKLEEsYTLNSDLARLGVQDLFNssK |
| P31153 | S247 | Sugiyama | MAT2A AMS2 MATA2 | IKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLtGRKII |
| P31327 | S205 | Sugiyama | CPS1 | FEGQPVDFVDPNKQNLIAEVstKDVKVYGKGNPTKVVAVDC |
| P31327 | S808 | Sugiyama | CPS1 | IGSSMKsVGEVMAIGRTFEEsFQKALRMCHPsIEGFTPRLP |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P31327 | T326 | Sugiyama | CPS1 | AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP |
| P31327 | T900 | Sugiyama | CPS1 | KMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKC |
| P31327 | T903 | Sugiyama | CPS1 | DILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKCLGL |
| P31939 | S370 | Sugiyama | ATIC PURH OK/SW-cl.86 | ALTILSKKKNGNyCVLQMDQsYKPDENEVRTLFGLHLsQKR |
| P31943 | S285 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | NyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDI |
| P31946 | S147 | Sugiyama | YWHAB | YFRyLsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHP |
| P31946 | S158 | Sugiyama | YWHAB | DNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV |
| P31946 | S47 | Sugiyama | YWHAB | AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P31947 | S45 | Sugiyama | SFN HME1 | FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI |
| P31948 | S459 | Sugiyama | STIP1 | EAMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRH |
| P31948 | S460 | Sugiyama | STIP1 | AMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRHD |
| P32929 | S61 | Sugiyama | CTH | ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA |
| P33176 | S950 | Sugiyama | KIF5B KNS KNS1 | PAAsPtHPSAIRGGGAFVQNsQPVAVRGGGGKQV_______ |
| P34896 | S17 | Sugiyama | SHMT1 | ____MTMPVNGAHKDADLWSsHDKMLAQPLKDSDVEVyNII |
| P34897 | S417 | Sugiyama | SHMT2 | ERVLELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFR |
| P34897 | S76 | Sugiyama | SHMT2 | MWELLQREKDRQCRGLELIAsENFCsRAALEALGsCLNNKY |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34931 | T228 | Sugiyama | HSPA1L | DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK |
| P34931 | T47 | Sugiyama | HSPA1L | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN |
| P34931 | T49 | Sugiyama | HSPA1L | EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV |
| P35221 | S295 | Sugiyama | CTNNA1 | GGELAyALNNFDKQIIVDPLsFsEERFRPSLEERLESIISG |
| P35221 | S668 | Sugiyama | CTNNA1 | FDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEQKAKIAEQV |
| P35579 | S1713 | Sugiyama | MYH9 | ERAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQ |
| P35579 | T1155 | Sugiyama | MYH9 | RDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKKT |
| P35613 | S279 | Sugiyama | BSG UNQ6505/PRO21383 | TDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQy |
| P36578 | S63 | Sugiyama | RPL4 RPL1 | NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P36871 | S134 | Sugiyama | PGM1 | LtAsHNPGGPNGDFGIKFNIsNGGPAPEAITDKIFQISKTI |
| P36871 | S483 | Sugiyama | PGM1 | DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37802 | T190 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________ |
| P38646 | S200 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | NyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNVLRVI |
| P38646 | S549 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P38646 | T120 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV |
| P38646 | Y118 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P40855 | S147 | Sugiyama | PEX19 HK33 PXF OK/SW-cl.22 | SCLKETLSGLAKNATDLQNssMsEEELTKAMEGLGMDEGDG |
| P40925 | S153 | Sugiyama | MDH1 MDHA | ANtNCLtAsKSAPSIPKENFsCLtRLDHNRAKAQIALKLGV |
| P41091 | S108 | Sugiyama | EIF2S3 EIF2G | IYKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVR |
| P41252 | T1068 | Sugiyama | IARS1 IARS | PsDKVLIQEKTQLKGSELEItLTRGSSLPGPACAYVNLNIC |
| P42677 | S78 | Sugiyama | RPS27 MPS1 | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| P42704 | S1027 | Sugiyama | LRPPRC LRP130 | VPFDVPELWyEDEKHsLNsssAsttEPDFQKDILIACRLNQ |
| P43034 | S157 | Sugiyama | PAFAH1B1 LIS1 MDCR MDS PAFAHA | yEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADMTIKLW |
| P43243 | S211 | Sugiyama | MATR3 KIAA0723 | DRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDDRLRDGERCR |
| P43490 | S180 | Sugiyama | NAMPT PBEF PBEF1 | TVATNSREQKKILAKyLLEtsGNLDGLEyKLHDFGyRGVSS |
| P45974 | S783 | Sugiyama | USP5 ISOT | IDDLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQL |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46777 | S172 | Sugiyama | RPL5 MSTP030 | RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA |
| P46777 | S176 | Sugiyama | RPL5 MSTP030 | GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR |
| P46782 | S75 | Sugiyama | RPS5 | RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH |
| P46783 | S146 | Sugiyama | RPS10 | TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_ |
| P46937 | S405 | Sugiyama | YAP1 YAP65 | FLNsGtyHsRDEstDsGLsMssysVPRtPDDFLNsVDEMDT |
| P47712 | S729 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA |
| P47756 | S192 | Sugiyama | CAPZB | TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN |
| P48426 | S115 | Sugiyama | PIP4K2A PI5P4KA PIP5K2 PIP5K2A | PMVFRNLRERFGIDDQDFQNsLTRSAPLPNDSQARSGARFH |
| P48444 | S138 | Sugiyama | ARCN1 COPD | ALGYRENVNLAQIRTFTEMDsHEEKVFRAVRETQEREAKAE |
| P48444 | S253 | Sugiyama | ARCN1 COPD | KEVDNFVDKLKsEGEtIMSssMGKRTSEATKMHAPPINMES |
| P48739 | S165 | Sugiyama | PITPNB | DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P48741 | T228 | Sugiyama | HSPA7 HSP70B | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P48741 | T47 | Sugiyama | HSPA7 HSP70B | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P48741 | T49 | Sugiyama | HSPA7 HSP70B | EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV |
| P49321 | S704 | Sugiyama | NASP | PGGGGssVsMIASRKPtDGAsssNCVTDIsHLVRKKRKPEE |
| P49321 | S705 | Sugiyama | NASP | GGGGssVsMIASRKPtDGAsssNCVTDIsHLVRKKRKPEEE |
| P49321 | S713 | Sugiyama | NASP | MIASRKPtDGAsssNCVTDIsHLVRKKRKPEEEsPRKDDAK |
| P49327 | S2039 | Sugiyama | FASN FAS | FSSVSCGRGNAGQsNyGFANsAMERICEKRRHEGLPGLAVQ |
| P49327 | S324 | Sugiyama | FASN FAS | ELNGItRALCAtRQEPLLIGsTKSNMGHPEPASGLAALAKV |
| P49327 | S63 | Sugiyama | FASN FAS | GLyGLPRRsGKLKDLSRFDAsFFGVHPKQAHTMDPQLRLLL |
| P49327 | T1718 | Sugiyama | FASN FAS | TVGSAEKRAYLQARFPQLDstSFANSRDtsFEQHVLWHTGG |
| P49327 | T315 | Sugiyama | FASN FAS | tGTKVGDPQELNGItRALCAtRQEPLLIGsTKSNMGHPEPA |
| P49368 | S458 | Sugiyama | CCT3 CCTG TRIC5 | RAVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtW |
| P49368 | T373 | Sugiyama | CCT3 CCTG TRIC5 | KKIGDEYFTFITDCKDPKACtILLRGAsKEILSEVERNLQD |
| P49589 | S305 | Sugiyama | CARS1 CARS | KLVPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKA |
| P49736 | S170 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | KRRQVERAtEDGEEDEEMIEsIENLEDLKGHSVREWVsMAG |
| P49792 | S1550 | Sugiyama | RANBP2 NUP358 | KTLKSGFEDMFAKKEGQWDCsSCLVRNEANATRCVACQNPD |
| P49792 | S1613 | Sugiyama | RANBP2 NUP358 | KAPKSGFEGMFTKKEGQWDCsVCLVRNEASATKCIACQNPG |
| P49792 | S1832 | Sugiyama | RANBP2 NUP358 | KPIAEAPsAFTLGSEMKLHDssGsQVGtGFKSNFSEKASKF |
| P49792 | S1981 | Sugiyama | RANBP2 NUP358 | FGKKDPNFKGFSGAGEKLFSsQYGKMANKANtsGDFEKDDD |
| P50395 | S396 | Sugiyama | GDI2 RABGDIB | IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD |
| P50395 | T413 | Sugiyama | GDI2 RABGDIB | GtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFEE |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50454 | S141 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI |
| P50897 | T261 | Sugiyama | PPT1 CLN1 PPT | SEWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLV |
| P50991 | T199 | Sugiyama | CCT4 CCTD SRB | YSSLLsPMSVNAVMKVIDPAtAtsVDLRDIKIVKKLGGTID |
| P50991 | T201 | Sugiyama | CCT4 CCTD SRB | SLLsPMSVNAVMKVIDPAtAtsVDLRDIKIVKKLGGTIDDC |
| P50995 | S490 | Sugiyama | ANXA11 ANX11 | RSEYKRMYGKsLyHDISGDtsGDyRKILLKICGGND_____ |
| P51532 | S1382 | Sugiyama | SMARCA4 BAF190A BRG1 SNF2B SNF2L4 | EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE |
| P52209 | S126 | Sugiyama | PGD PGDH | YRDTTRRCRDLKAKGILFVGsGVsGGEEGARyGPSLMPGGN |
| P52209 | S405 | Sugiyama | PGD PGDH | ELQNLLLDDFFKSAVENCQDsWRRAVSTGVQAGIPMPCFTT |
| P52272 | S633 | Sugiyama | HNRNPM HNRPM NAGR1 | GGGGAsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKAC |
| P52272 | S637 | Sugiyama | HNRNPM HNRPM NAGR1 | AsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKACQIFV |
| P52565 | S148 | Sugiyama | ARHGDIA GDIA1 | YIQHTyRKGVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKG |
| P52732 | S1033 | SIGNOR|PSP | KIF11 EG5 KNSL1 TRIP5 | QHKKSHGKDKENRGINTLERsKVEETtEHLVTKSRLPLRAQ |
| P52789 | S889 | Sugiyama | HK2 | PHFAKVMHETVKDLAPKCDVsFLQsEDGSGKGAALITAVAC |
| P52888 | S29 | Sugiyama | THOP1 | GDMADAAsPCSVVNDLRWDLsAQQIEERTRELIEQTKRVyD |
| P52907 | S215 | Sugiyama | CAPZA1 | QVHYYEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENA |
| P52907 | S219 | Sugiyama | CAPZA1 | YEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAENEy |
| P52907 | T217 | Sugiyama | CAPZA1 | HYYEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAEN |
| P53999 | S57 | Sugiyama | SUB1 PC4 RPO2TC1 | VKKQKTGETsRALsssKQssssRDDNMFQIGKMRYVSVRDF |
| P54105 | S193 | Sugiyama | CLNS1A CLCI ICLN | GLSHLTAEGQATLERLEGMLsQsVssQYNMAGVRtEDsIRD |
| P54136 | S329 | Sugiyama | RARS1 RARS | KLICDVSRQELNKIyDALDVsLIERGEsFYQDRMNDIVKEF |
| P54136 | S336 | Sugiyama | RARS1 RARS | RQELNKIyDALDVsLIERGEsFYQDRMNDIVKEFEDRGFVQ |
| P54252 | S260 | Sugiyama | ATXN3 ATX3 MJD MJD1 SCA3 | IDMEDEEADLRRAIQLsMQGssRNIsQDMtQtsGTNLTSEE |
| P54274 | S114 | SIGNOR|PSP | TERF1 PIN2 TRBF1 TRF TRF1 | RSEDFRRTRNSAEAIIHGLSsLTACQLRtIYICQFLTRIAA |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P54652 | T46 | Sugiyama | HSPA2 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN |
| P54652 | T48 | Sugiyama | HSPA2 | EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI |
| P55036 | S358 | Sugiyama | PSMD4 MCB1 | VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_ |
| P55036 | T264 | Sugiyama | PSMD4 MCB1 | AEAGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEE |
| P55060 | S931 | Sugiyama | CSE1L CAS XPO2 | KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL |
| P55072 | S459 | Sugiyama | VCP HEL-220 HEL-S-70 | AEVMNSLAVTMDDFRWALSQsNPSALRETVVEVPQVTWEDI |
| P55072 | S765 | Sugiyama | VCP HEL-220 HEL-S-70 | RsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGAGPsQ |
| P55209 | S69 | Sugiyama | NAP1L1 NRP | LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA |
| P55769 | S29 | Sugiyama | SNU13 NHP2L1 | KAyPLADAHLTKKLLDLVQQsCNyKQLRKGANEATKTLNRG |
| P56192 | S127 | Sugiyama | MARS1 MARS | GKKGEDVLGSVRRALTHIDHsLSRQNCPFLAGETESLADIV |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | T90 | Sugiyama | TPI1 TPI | VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60660 | T22 | Sugiyama | MYL6 | CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S239 | Sugiyama | ACTB | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P60709 | S365 | Sugiyama | ACTB | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S60 | Sugiyama | ACTB | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60709 | Y362 | Sugiyama | ACTB | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P60709 | Y53 | Sugiyama | ACTB | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P60763 | S158 | Sugiyama | RAC3 | TYPQGLAMAREIGSVKyLECsALtQRGLKtVFDEAIRAVLC |
| P60842 | S78 | Sugiyama | EIF4A1 DDX2A EIF4A | IQQRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDL |
| P61081 | S175 | Sugiyama | UBE2M UBC12 | NNRRLFEQNVQRSMRGGyIGstyFERCLK____________ |
| P61221 | Y594 | Sugiyama | ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 | RPRINKLNsIKDVEQKKsGNyFFLDD_______________ |
| P61247 | S236 | Sugiyama | RPS3A FTE1 MFTL | KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy |
| P61247 | S237 | Sugiyama | RPS3A FTE1 MFTL | MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE |
| P61254 | S9 | Sugiyama | RPL26 | ____________MKFNPFVtsDRsKNRKRHFNAPsHIRRKI |
| P61313 | S97 | Sugiyama | RPL15 EC45 TCBAP0781 | KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN |
| P61353 | T94 | Sugiyama | RPL27 | VyNyNHLMPtRysVDIPLDKtVVNKDVFRDPALKRKARREA |
| P61604 | S21 | Sugiyama | HSPE1 | MAGQAFRKFLPLFDRVLVERsAAETVTKGGIMLPEKSQGKV |
| P61769 | S75 | Sugiyama | B2M CDABP0092 HDCMA22P | IEVDLLKNGERIEKVEHsDLsFsKDWSFYLLYYTEFTPTEK |
| P61978 | S401 | Sugiyama | HNRNPK HNRPK | GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | S46 | Sugiyama | YWHAG | AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P62241 | S115 | Sugiyama | RPS8 OK/SW-cl.83 | TLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEE |
| P62241 | S160 | Sugiyama | RPS8 OK/SW-cl.83 | KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S117 | Sugiyama | YWHAE | CCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAEFAt |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S46 | Sugiyama | YWHAE | SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI |
| P62258 | T229 | Sugiyama | YWHAE | LsEEsyKDstLIMQLLRDNLtLWtsDMQGDGEEQNKEALQD |
| P62263 | S139 | Sugiyama | RPS14 PRO2640 | LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________ |
| P62266 | S45 | Sugiyama | RPS23 | KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62273 | Y7 | Sugiyama | RPS29 | ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR |
| P62277 | S12 | Sugiyama | RPS13 | _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD |
| P62277 | S14 | Sugiyama | RPS13 | _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK |
| P62280 | T54 | Sugiyama | RPS11 | PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs |
| P62736 | S241 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P62736 | S62 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62736 | Y55 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P62753 | T127 | Sugiyama | RPS6 OK/SW-cl.2 | SVLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNL |
| P62753 | T128 | Sugiyama | RPS6 OK/SW-cl.2 | VLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNLs |
| P62826 | T66 | Sugiyama | RAN ARA24 OK/SW-cl.81 | EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | S138 | Sugiyama | RPL8 | EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62979 | S134 | Sugiyama | RPS27A UBA80 UBCEP1 | IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE |
| P63000 | S158 | Sugiyama | RAC1 TC25 MIG5 | TYPQGLAMAKEIGAVKyLECsALtQRGLKtVFDEAIRAVLC |
| P63104 | S145 | Sugiyama | YWHAZ | YYRyLAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHP |
| P63104 | S156 | Sugiyama | YWHAZ | DDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | S45 | Sugiyama | YWHAZ | CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI |
| P63104 | T30 | Sugiyama | YWHAZ | AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN |
| P63173 | T14 | Sugiyama | RPL38 | _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S239 | Sugiyama | ACTG1 ACTG | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63261 | S365 | Sugiyama | ACTG1 ACTG | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S60 | Sugiyama | ACTG1 ACTG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63261 | Y362 | Sugiyama | ACTG1 ACTG | GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______ |
| P63261 | Y53 | Sugiyama | ACTG1 ACTG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P63267 | S240 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63267 | S61 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P63267 | Y54 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68032 | S241 | Sugiyama | ACTC1 ACTC | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68032 | S62 | Sugiyama | ACTC1 ACTC | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68032 | Y55 | Sugiyama | ACTC1 ACTC | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68104 | T432 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| P68133 | S241 | Sugiyama | ACTA1 ACTA | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68133 | S62 | Sugiyama | ACTA1 ACTA | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68133 | Y55 | Sugiyama | ACTA1 ACTA | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | T41 | Sugiyama | TUBA1B | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| P68363 | T56 | Sugiyama | TUBA1B | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T80 | Sugiyama | TUBA1B | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| P68363 | T82 | Sugiyama | TUBA1B | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| P78356 | S120 | Sugiyama | PIP4K2B PIP5K2B | PMVFRNLRERFGIDDQDyQNsVTRSAPINSDSQGRCGTRFL |
| P78371 | S438 | Sugiyama | CCT2 99D8.1 CCTB | AHAVTQLANRtPGKEAVAMEsyAKALRMLPTIIADNAGYDS |
| P78406 | S74 | Sugiyama | RAE1 MRNP41 | GNFLIAGSWANDVRCWEVQDsGQtIPKAQQMHTGPVLDVCW |
| P78417 | S23 | Sugiyama | GSTO1 GSTTLP28 | GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK |
| P78527 | S3363 | Sugiyama | PRKDC HYRC HYRC1 | SEPACLAEIEEDKARRILELsGsssEDsEKVIAGLyQRAFQ |
| P78527 | T2638 | Sugiyama | PRKDC HYRC HYRC1 | tRtQEGsLSARWPVAGQIRAtQQQHDFtLtQtADGRssFDW |
| P78527 | T2649 | Sugiyama | PRKDC HYRC HYRC1 | WPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstDPLVD |
| P83731 | S38 | Sugiyama | RPL24 | GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK |
| P84098 | S37 | Sugiyama | RPL19 | CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV |
| P84098 | T29 | Sugiyama | RPL19 | RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL |
| P99999 | S48 | Sugiyama | CYCS CYC | KTGPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEY |
| Q00610 | S1147 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | sYIKADDPSSYMEVVQAANTsGNWEELVKYLQMARKKAREs |
| Q00610 | S1222 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | GDRCyDEKMyDAAKLLyNNVsNFGRLAstLVHLGEyQAAVD |
| Q00610 | S886 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG |
| Q00839 | S585 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | KFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRKAVV |
| Q00839 | T582 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | CLGKFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRK |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01082 | S35 | Sugiyama | SPTBN1 SPTB2 | QQQYSDVNNRWDVDDWDNENsSARLFERSRIKALADEREAV |
| Q01105 | S133 | Sugiyama | SET | DEEALHYLTRVEVtEFEDIKsGyRIDFyFDENPyFENKVLS |
| Q01105 | S161 | Sugiyama | SET | FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK |
| Q01105 | S165 | Sugiyama | SET | PyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQ |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q01518 | T165 | Sugiyama | CAP1 CAP | AMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVKA |
| Q01844 | S443 | Sugiyama | EWSR1 EWS | AKAAVEWFDGKDFQGSKLKVsLARKKPPMNSMRGGLPPREG |
| Q02818 | S378 | Sugiyama | NUCB1 NUC | EAELNAKAQRLsQETEALGRsQGRLEAQKRELQQAVLHMEQ |
| Q04637 | S1134 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | RPAtstLNRFsALQQAVPtEsTDNRRVVQRssLsRERGEKA |
| Q04760 | T35 | Sugiyama | GLO1 | AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM |
| Q04864 | S274 | Sugiyama | REL | TEPVTVKMQLRRPSDQEVsEsMDFRYLPDEKDTYGNKAKKQ |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q05639 | T432 | Sugiyama | EEF1A2 EEF1AL STN | VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT |
| Q06265 | S287 | Sugiyama | EXOSC9 PMSCL1 | KALENDQKVRKEGGKFGFAEsIANQRITAFKMEKAPIDtsD |
| Q06323 | S31 | Sugiyama | PSME1 IFI5111 | QAKVDVFREDLCTKtENLLGsyFPKKIsELDAFLKEPALNE |
| Q06323 | S55 | Sugiyama | PSME1 IFI5111 | KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE |
| Q06830 | T18 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | ___MSSGNAKIGHPAPNFKAtAVMPDGQFKDIsLsDyKGKY |
| Q07021 | S210 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS |
| Q08211 | S625 | Sugiyama | DHX9 DDX9 LKP NDH2 | DANCNLICGDEyGPETRLsMsQLNEKETPFELIEALLKYIE |
| Q08378 | S1093 | Sugiyama | GOLGA3 | SQELEESREKVLELEDELQEsRGFRKKIKRLEESNKKLALE |
| Q08AD1 | S473 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | stPNRGITRsIsNEGLtLNNsHVsKHIRKNLSFKPINGEEE |
| Q12874 | S482 | Sugiyama | SF3A3 SAP61 | LKLQKASERWQPDtEEEyEDssGNVVNKKTYEDLKRQGLL_ |
| Q13148 | S292 | Sugiyama | TARDBP TDP43 | RsGRFGGNPGGFGNQGGFGNsRGGGAGLGNNQGsNMGGGMN |
| Q13162 | S73 | Sugiyama | PRDX4 | FyAGGQVyPGEAsRVsVADHsLHLSKAKISKPAPYWEGTAV |
| Q13283 | S362 | Sugiyama | G3BP1 G3BP | LFIGNLPHEVDKSELKDFFQsyGNVVELRINsGGKLPNFGF |
| Q13310 | T191 | Sugiyama | PABPC4 APP1 PABP4 | GRFKSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELF |
| Q13310 | Y194 | Sugiyama | PABPC4 APP1 PABP4 | KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF |
| Q13347 | S217 | Sugiyama | EIF3I EIF3S2 TRIP1 | sRDMtMFVtASKDNTAKLFDsttLEHQKTFRTERPVNSAAL |
| Q13509 | S75 | Sugiyama | TUBB3 TUBB4 | SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS |
| Q13509 | T72 | Sugiyama | TUBB3 TUBB4 | NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF |
| Q13617 | S230 | Sugiyama | CUL2 | PFLTETGEYYKQEASNLLQEsNCSQYMEKVLGRLKDEEIRC |
| Q13765 | S117 | Sugiyama | NACA HSD48 | RKSKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQL |
| Q13765 | S132 | Sugiyama | NACA HSD48 | YKSPAsDtyIVFGEAKIEDLsQQAQLAAAEKFKVQGEAVsN |
| Q13765 | S186 | Sugiyama | NACA HSD48 | sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI |
| Q13765 | T119 | Sugiyama | NACA HSD48 | SKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAA |
| Q13885 | S75 | Sugiyama | TUBB2A TUBB2 | AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q13885 | T72 | Sugiyama | TUBB2A TUBB2 | NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| Q14152 | S1256 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EDRFRRPRDEGGWRRGPAEEsssWRDssRRDDRDRDDRRRE |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14157 | T256 | Sugiyama | UBAP2L KIAA0144 NICE4 | AWRtAtEEWGtEDWNEDLsEtKIFtAsNVssVPLPAENVtI |
| Q14192 | S13 | Sugiyama | FHL2 DRAL SLIM3 | ________MTERFDCHHCNEsLFGKKYILREESPYCVVCFE |
| Q14240 | S79 | Sugiyama | EIF4A2 DDX2B EIF4F | IQQRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEF |
| Q14247 | S432 | Sugiyama | CTTN EMS1 | EERLPssPVyEDAAsFKAELsyRGPVsGtEPEPVysMEAAD |
| Q14498 | T347 | Sugiyama | RBM39 HCC1 RNPC2 | TERtDAssAssFLDsDELERtGIDLGtTGRLQLMARLAEGT |
| Q14498 | T353 | Sugiyama | RBM39 HCC1 RNPC2 | ssAssFLDsDELERtGIDLGtTGRLQLMARLAEGTGLQIPP |
| Q14566 | S341 | Sugiyama | MCM6 | tAEsIKNQMTVKEWEKVFEMsQDKNLYHNLCTSLFPTIHGN |
| Q14568 | S164 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGT |
| Q14568 | S165 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14683 | S649 | Sugiyama | SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 | AFGGHQRHKtVALDGtLFQKsGVISGGASDLKAKARRWDEK |
| Q14974 | S201 | Sugiyama | KPNB1 NTF97 | MRKEEPSNNVKLAAtNALLNsLEFTKANFDKESERHFIMQV |
| Q14974 | T195 | Sugiyama | KPNB1 NTF97 | TAIIQGMRKEEPSNNVKLAAtNALLNsLEFTKANFDKESER |
| Q14980 | S1181 | Sugiyama | NUMA1 NMP22 NUMA | DsALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQD |
| Q15021 | S1310 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | RACHTRGLDGIKELEIGQAGsQRAPsAKKPSTGSRyQPLAs |
| Q15043 | S56 | Sugiyama | SLC39A14 KIAA0062 ZIP14 | PAISAASFLQDLIHRYGEGDsLTLQQLKALLNHLDVGVGRG |
| Q15056 | S110 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK |
| Q15058 | S1217 | SIGNOR|EPSD|PSP | KIF14 KIAA0042 | RRIsGCLHDIQVHPIKNLHSsHssGLMDKsstIysNsAESF |
| Q15058 | S1219 | SIGNOR|EPSD|PSP | KIF14 KIAA0042 | IsGCLHDIQVHPIKNLHSsHssGLMDKsstIysNsAESFLP |
| Q15058 | S1220 | SIGNOR|EPSD|PSP | KIF14 KIAA0042 | sGCLHDIQVHPIKNLHSsHssGLMDKsstIysNsAESFLPG |
| Q15058 | S56 | SIGNOR|EPSD|PSP | KIF14 KIAA0042 | LKLHLKSDMSECENDDPLLRsAGKVRDINRtYVISASRKTA |
| Q15058 | S607 | SIGNOR|EPSD|PSP | KIF14 KIAA0042 | EGEEHDHRITSRINLIDLAGsERCSTAHTNGDRLKEGVSIN |
| Q15084 | S169 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | GKQGRSDsSSKKDVIELtDDsFDKNVLDSEDVWMVEFYAPW |
| Q15084 | S230 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | QTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIFQKGEsPV |
| Q15084 | S375 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | GYPAMAAINARKMKFALLKGsFsEQGINEFLRELsFGRGst |
| Q15084 | T223 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | AAsEVKEQTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIF |
| Q15126 | S66 | Sugiyama | PMVK PMKI | PLKEQYAQEHGLNFQRLLDTsTYKEAFRKDMIRWGEEKRQA |
| Q15185 | S118 | Sugiyama | PTGES3 P23 TEBP | WLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGDEDVDL |
| Q15185 | S72 | Sugiyama | PTGES3 P23 TEBP | EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE |
| Q15293 | S80 | Sugiyama | RCN1 RCN | HEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGDGFVt |
| Q15382 | S140 | Sugiyama | RHEB RHEB2 | KKDLHMERVIsYEEGKALAEsWNAAFLEssAKENQTAVDVF |
| Q15382 | S148 | Sugiyama | RHEB RHEB2 | VIsYEEGKALAEsWNAAFLEssAKENQTAVDVFRRIILEAE |
| Q15382 | S149 | Sugiyama | RHEB RHEB2 | IsYEEGKALAEsWNAAFLEssAKENQTAVDVFRRIILEAEK |
| Q15393 | T689 | Sugiyama | SF3B3 KIAA0017 SAP130 | LQNGVLLRTVLDPVTGDLSDtRTRYLGSRPVKLFRVRMQGQ |
| Q15545 | S200 | Sugiyama | TAF7 TAF2F TAFII55 | RWEIIAEDETKEAENQGLDIssPGMsGHRQGHDsLEHDELR |
| Q15751 | S1541 | Sugiyama | HERC1 | sDEEGYALsGRRNVDLDLAAsHRKRGPMHSQLESLSDsWAR |
| Q16401 | S98 | Sugiyama | PSMD5 KIAA0072 | VHVARNLRVDLQRGLIHPDDsVKILTLSQIGRIVENSDAVT |
| Q16531 | S379 | Sugiyama | DDB1 XAP1 | IVDMCVVDLERQGQGQLVTCsGAFKEGSLRIIRNGIGIHEH |
| Q16658 | S259 | Sugiyama | FSCN1 FAN1 HSN SNL | tLKAGKATKVGKDELFALEQsCAQVVLQAANERNVsTRQGM |
| Q16658 | T239 | Sugiyama | FSCN1 FAN1 HSN SNL | GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs |
| Q16762 | S35 | Sugiyama | TST | WLAESIRTGKLGPGLRVLDAsWysPGTREARKEYLERHVPG |
| Q27J81 | S1192 | Sugiyama | INF2 C14orf151 C14orf173 | EDEDEEDtAPEsALDtsLDKsFsEDAVtDssGsGtLPRARG |
| Q32P51 | S95 | Sugiyama | HNRNPA1L2 HNRNPA1L | TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| Q3ZCM7 | S75 | Sugiyama | TUBB8 | SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC |
| Q49A26 | S540 | Sugiyama | GLYR1 HIBDL NDF NP60 NPAC | PTPMAAAANEVYKRAKALDQsDNDMSAVyRAYIH_______ |
| Q53EL6 | S49 | Sugiyama | PDCD4 H731 | ENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNssR |
| Q562R1 | S240 | Sugiyama | ACTBL2 | VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | T489 | Sugiyama | HSP90AB3P HSP90BC | YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME |
| Q5H9R7 | S579 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | IDQFGFNDEKFADQDDIGNVsFDRVSDINFTLNTNESGNIA |
| Q5SW79 | S551 | Sugiyama | CEP170 FAM68A KAB KIAA0470 | DyNRPVINEKHKDLIKDWALssAAAVMEERKPLTTSGFHHs |
| Q5T1M5 | S1092 | Sugiyama | FKBP15 KIAA0674 | DNPSGKVCVREVAPDGPLQEsstRLsLtsDPEEGDPLALGP |
| Q5T1V6 | S165 | Sugiyama | DDX59 ZNHIT5 | KSKLSNPQKADsEPEsPLNAsYVYKEHPFILNLQEDQIENL |
| Q5T4S7 | S2743 | Sugiyama | UBR4 KIAA0462 KIAA1307 RBAF600 | NtPMGDKDDDDDDDADEKMQsSGIPNGGHIRQESQEQSEVD |
| Q5VT52 | S1177 | Sugiyama | RPRD2 KIAA0460 HSPC099 | GGLTGFKTAPYKERAPQFQEsVGsFRsNsFNstFEHHLPPs |
| Q5VTE0 | T432 | Sugiyama | EEF1A1P5 EEF1AL3 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| Q5VZL5 | S242 | Sugiyama | ZMYM4 KIAA0425 ZNF262 | FRDSSYPFANKESIGSELGNsFAsNIRIKEEPLDDEYDKAM |
| Q6PCE3 | S316 | Sugiyama | PGM2L1 BM32A | PDFSTVKCPNPEEGEsVLELsLRLAEKENARVVLATDPDAD |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | T41 | Sugiyama | TUBA3E | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q6PEY2 | T56 | Sugiyama | TUBA3E | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| Q6S8J3 | S1065 | Sugiyama | POTEE A26C1A POTE2 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | S939 | Sugiyama | POTEE A26C1A POTE2 | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6S8J3 | Y1062 | Sugiyama | POTEE A26C1A POTE2 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | T41 | Sugiyama | TUBA1A TUBA3 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q71U36 | T56 | Sugiyama | TUBA1A TUBA3 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T80 | Sugiyama | TUBA1A TUBA3 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q71U36 | T82 | Sugiyama | TUBA1A TUBA3 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q71UM5 | S78 | Sugiyama | RPS27L | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| Q7KZF4 | S909 | Sugiyama | SND1 TDRD11 | RLNLWRyGDFRADDADEFGysR___________________ |
| Q7KZI7 | T478 | Sugiyama | MARK2 EMK1 | LPGLERKKttPtPstNSVLststNRsRNsPLLERAsLGQAs |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q7Z4H7 | S856 | Sugiyama | HAUS6 DGT6 FAM29A KIAA1574 | RYEALKKSLSKKREESyLSNsQtPERHKPELsPtPQNVQtD |
| Q86U42 | S235 | Sugiyama | PABPN1 PAB2 PABP2 | FAyIEFSDKEsVRTSLALDEsLFRGRQIKVIPKRTNRPGIS |
| Q86U44 | S358 | Sugiyama | METTL3 MTA70 | DSEAPGsKDHtPsQELALTQsVGGDSSADRLFPPQWICCDI |
| Q86UF2 | S140 | Sugiyama | CTAGE6 CTAGE6P | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q86V81 | S8 | Sugiyama | ALYREF ALY BEF THOC4 | _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG |
| Q8IUD2 | S824 | Sugiyama | ERC1 ELKS KIAA1081 RAB6IP2 | KKKsAQMLEEARRREDNLNDsSQQLQDSLRKKDDRIEELEE |
| Q8IWZ3 | S1131 | Sugiyama | ANKHD1 KIAA1085 MASK VBARP PP2500 | GGDIEAQSERTKDTPLSLACsGGRQEVVDLLLARGANKEHR |
| Q8IX94 | S140 | Sugiyama | CTAGE4 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q8N1F7 | S72 | Sugiyama | NUP93 KIAA0095 | sQETADVKASVLLGsRGLDIsHIsQRLEsLsAAtTFEPLEP |
| Q8N6H7 | S368 | Sugiyama | ARFGAP2 ZNF289 Nbla10535 | VGTFASGPPKYKDNPFsLGEsFGsRWDTDAAWGMDRVEEKE |
| Q8N6T3 | S246 | Sugiyama | ARFGAP1 ARF1GAP | KEGATKFGSQASQKASELGHsLNENVLKPAQEKVKEGKIFD |
| Q8NBK3 | S357 | Sugiyama | SUMF1 PSEC0152 UNQ3037/PRO9852 | HRSYCYRYRCAARSQNTPDSsAsNLGFRCAADRLPtMD___ |
| Q8NBP7 | S487 | Sugiyama | PCSK9 NARC1 PSEC0052 | PTRMATAVARCAPDEELLsCssFSRSGKRRGERMEAQGGKL |
| Q8NE71 | S287 | Sugiyama | ABCF1 ABC50 | YERQVASLKAANAAENDFsVsQAEMSsRQAMLENASDIKLE |
| Q8NEY8 | S329 | Sugiyama | PPHLN1 HSPC206 HSPC232 | CETFGMVVKMLIEKDPsLEKsIQFALRQNLHEIESAGQTWQ |
| Q8NEZ2 | S324 | Sugiyama | VPS37A HCRP1 | LTQMKSTFEKKMQRQHELSEsCsASALQARLKVAAHEAEEE |
| Q8NEZ2 | S326 | Sugiyama | VPS37A HCRP1 | QMKSTFEKKMQRQHELSEsCsASALQARLKVAAHEAEEESD |
| Q8TAM6 | S280 | Sugiyama | ERMN KIAA1189 | TISYRKIRKGNTKQRIDEFEsMMHL________________ |
| Q8TDX7 | S195 | Sugiyama | NEK7 | VKLGDLGLGRFFssKttAAHsLVGtPyYMsPERIHENGYNF |
| Q8TDX7 | S245 | Sugiyama | NEK7 | LLYEMAALQSPFYGDKMNLYsLCKKIEQCDYPPLPsDHYSE |
| Q8TDX7 | S260 | Sugiyama | NEK7 | KMNLYsLCKKIEQCDYPPLPsDHYSEELRQLVNMCINPDPE |
| Q8TDX7 | S46 | Sugiyama | NEK7 | MGYNTLANFRIEKKIGRGQFsEVYRAACLLDGVPVALKKVQ |
| Q8TDX7 | T190 | Sugiyama | NEK7 | TATGVVKLGDLGLGRFFssKttAAHsLVGtPyYMsPERIHE |
| Q8TDX7 | T191 | Sugiyama | NEK7 | ATGVVKLGDLGLGRFFssKttAAHsLVGtPyYMsPERIHEN |
| Q8TDX7 | T199 | Sugiyama | NEK7 | DLGLGRFFssKttAAHsLVGtPyYMsPERIHENGYNFKSDI |
| Q8TDX7 | Y201 | Sugiyama | NEK7 | GLGRFFssKttAAHsLVGtPyYMsPERIHENGYNFKSDIWS |
| Q8WWM7 | S273 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | PNEMFKFNEENyGVKTtyDssLssytVPLEKDNsEEFRQRE |
| Q92878 | S878 | Sugiyama | RAD50 | EQIQHLKSTTNELKSEKLQIsTNLQRRQQLEEQTVELSTEV |
| Q92890 | S217 | Sugiyama | UFD1 UFD1L | YKEPERQVQHEEstEGEADHsGyAGELGFRAFsGsGNRLDG |
| Q969M3 | S45 | Sugiyama | YIPF5 FINGER5 YIP1A PP12723 SB140 UNQ3123/PRO10275 | SYDYGGSGGPYSKQYAGyDysQQGRFVPPDMMQPQQPYTGQ |
| Q969M3 | Y44 | Sugiyama | YIPF5 FINGER5 YIP1A PP12723 SB140 UNQ3123/PRO10275 | QSYDYGGSGGPYSKQYAGyDysQQGRFVPPDMMQPQQPYTG |
| Q96AE4 | S52 | Sugiyama | FUBP1 | KDALQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQ |
| Q96AE4 | S55 | Sugiyama | FUBP1 | LQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQPDA |
| Q96AG4 | S47 | Sugiyama | LRRC59 PRO1855 | LNEVPVKELAALPKATILDLsCNKLTTLPSDFCGLtHLVKL |
| Q96EP5 | S208 | Sugiyama | DAZAP1 | AEPRDsKsQAPGQPGAsQWGsRVVPNAANGWAGQPPPTWQQ |
| Q96FV9 | T650 | Sugiyama | THOC1 HPR1 | PENLINALNKsGLSDLAESLtNDNETNs_____________ |
| Q96HE7 | S143 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD |
| Q96PK6 | S620 | Sugiyama | RBM14 SIP | KRYGSDRRLAELsDYRRLsEsQLsFRRsPtKSSLDYRRLPD |
| Q96PZ0 | S571 | Sugiyama | PUS7 KIAA1897 | LTADNLDIDNMRHKIRDysLsGAyRKIIIRPQNVSWEVVAY |
| Q96T51 | S80 | Sugiyama | RUFY1 RABIP4 ZFYVE12 | EGWSAPILTLARRAtGNLsAsCGSALRAAAGLGGGDSGDGT |
| Q99497 | S57 | Sugiyama | PARK7 | GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL |
| Q99575 | S75 | Sugiyama | POP1 KIAA0061 | RQRQTRVNPHsLPDPEVNEQsssKGMFRKKGGWKAGPEGTs |
| Q99613 | S639 | Sugiyama | EIF3C EIF3S8 | CAFRQGLTKDAHNALLDIQssGRAKELLGQGLLLRSLQERN |
| Q99615 | S88 | Sugiyama | DNAJC7 TPR2 TTC2 | RAATLMMLGRFREALGDAQQsVRLDDsFVRGHLREGKCHLS |
| Q99832 | T351 | Sugiyama | CCT7 CCTH NIP7-1 | QtSVNALSADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCt |
| Q99832 | T458 | Sugiyama | CCT7 CCTH NIP7-1 | yAKALEIIPRQLCDNAGFDAtNILNKLRARHAQGGTWYGVD |
| Q9BQ69 | T91 | Sugiyama | MACROD1 LRP16 | RTAGVRTWAPLAMAAKVDLStsTDWKEAKSFLKGLSDKQRE |
| Q9BQE3 | S439 | Sugiyama | TUBA1C TUBA6 | SEAREDMAALEKDyEEVGADsADGEDEGEEy__________ |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | T41 | Sugiyama | TUBA1C TUBA6 | WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH |
| Q9BQE3 | T56 | Sugiyama | TUBA1C TUBA6 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T80 | Sugiyama | TUBA1C TUBA6 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q9BQE3 | T82 | Sugiyama | TUBA1C TUBA6 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q9BRA2 | S41 | Sugiyama | TXNDC17 TXNL5 | QHNGKTIFAyFTGSKDAGGKsWCPDCVQAEPVVREGLKHIS |
| Q9BRK5 | S142 | Sugiyama | SDF4 CAB45 PSEC0034 | EMQRWIMEKTAEHFQEAMEEsKTHFRAVDPDGDGHVsWDEy |
| Q9BT78 | S16 | Sugiyama | COPS4 CSN4 | _____MAAAVRQDLAQLMNSsGsHKDLAGKYRQILEKAIQL |
| Q9BTE6 | S184 | Sugiyama | AARSD1 | DRLPVNVRELsLDDPEVEQVsGRGLPDDHAGPIRVVNIEGV |
| Q9BUJ2 | T507 | Sugiyama | HNRNPUL1 E1BAP5 HNRPUL1 | CLNRLIQIAARKKRNyILDQtNVyGsAQRRKMRPFEGFQRK |
| Q9BV86 | S63 | Sugiyama | NTMT1 C9orf32 METTL11A NRMT NRMT1 AD-003 | NSSRKFLQRFLREGPNKTGtsCALDCGAGIGRITKRLLLPL |
| Q9BVA1 | S75 | Sugiyama | TUBB2B | tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q9BVA1 | T72 | Sugiyama | TUBB2B | NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| Q9BXP5 | S703 | Sugiyama | SRRT ARS2 ASR2 | EEAQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKFK |
| Q9BYX7 | S239 | Sugiyama | POTEKP ACTBL3 FKSG30 | VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE |
| Q9BYX7 | S365 | Sugiyama | POTEKP ACTBL3 FKSG30 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9BYX7 | Y362 | Sugiyama | POTEKP ACTBL3 FKSG30 | GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______ |
| Q9GZL7 | S230 | Sugiyama | WDR12 | DKMLKIWStVPtDEEDEMEEsTNRPRKKQKTEQLGLTRTPI |
| Q9GZZ9 | S24 | Sugiyama | UBA5 UBE1DC1 | SVERLQQRVQELERELAQERsLQVPRSGDGGGGRVRIEKMs |
| Q9H173 | T125 | Sugiyama | SIL1 UNQ545/PRO836 | QYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEME |
| Q9H1H9 | S1754 | Sugiyama | KIF13A RBKIN | sFTEFMGVSEGKDFDGLTDssAGELssRRsLPNKTGGKTVS |
| Q9H2M9 | S455 | Sugiyama | RAB3GAP2 KIAA0839 | TVEDLHERVPEKADFsPFGNsQGPSRVAQFLVIYAPRRGIL |
| Q9H2U2 | S313 | Sugiyama | PPA2 HSPC124 | VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG |
| Q9H3N1 | S228 | Sugiyama | TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 | PSKRRRPQPYPYPSKKLLsEsAQPLKKVEEEQEADEEDVsE |
| Q9H3N1 | S92 | Sugiyama | TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 | WGEDLEVNIAKVDVTEQPGLsGRFIITALPTIYHCKDGEFR |
| Q9H6T3 | S348 | Sugiyama | RPAP3 | KIQKYEEAEKDCTQAILLDGsYSKAFARRGTARTFLGKLNE |
| Q9H788 | S187 | Sugiyama | SH2D4A PPP1R38 SH2A | EEKIRSLSSSSRNIQQMLADsINRMKAYAFHQKKESMKKKQ |
| Q9H788 | S317 | Sugiyama | SH2D4A PPP1R38 SH2A | SGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRAGY |
| Q9HB71 | T209 | Sugiyama | CACYBP S100A6BP SIP PNAS-107 | EGLMNVLKKIyEDGDDDMKRtINKAWVESREKQAKGDTEF_ |
| Q9HC35 | S146 | SIGNOR | EML4 C2orf2 EMAPL4 | REKKEEsHsNDQsPQIRAsPsPQPssQPLQIHRQtPEsKNA |
| Q9NP81 | S184 | Sugiyama | SARS2 SARSM | YLQALKLPNQTHPDVPVGDEsQARVLHMVGDKPVFSFQPRG |
| Q9NQ39 | S157 | Sugiyama | RPS10P5 RPS10L | TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_ |
| Q9NQE9 | S46 | Sugiyama | HINT3 | VssVGTCEAAGKsPEPKDyDstCVFCRIAGRQDPGTELLHC |
| Q9NQR4 | S137 | Sugiyama | NIT2 CUA002 | DIDVPGKITFQESKTLsPGDsFSTFDTPyCRVGLGICYDMR |
| Q9NRX4 | T119 | Sugiyama | PHPT1 PHP14 CGI-202 HSPC141 | PAQHAISTEKIKAKyPDyEVtWANDGy______________ |
| Q9NY33 | S190 | Sugiyama | DPP3 | TYFSGNCTMEDAKLAQDFLDsQNLsAyNtRLFKEVDGEGKP |
| Q9NY33 | S194 | Sugiyama | DPP3 | GNCTMEDAKLAQDFLDsQNLsAyNtRLFKEVDGEGKPYYEV |
| Q9NYB9 | S22 | Sugiyama | ABI2 ARGBPIA | AELQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSAD |
| Q9NYF8 | S205 | Sugiyama | BCLAF1 BTF KIAA0164 | EEPKDtFEHDPsEsIDEFNKssAtsGDIWPGLsAyDNsPRs |
| Q9NYU2 | T808 | Sugiyama | UGGT1 GT UGCGL1 UGGT UGT1 UGTR | SNNVRISMINNPAKEISYENtQISRAIWAALQTQTSNAAKN |
| Q9UBC2 | S518 | Sugiyama | EPS15L1 EPS15R | LNRAKSELNRLQQEETQLEQsIQAGRVQLETIIKSLKSTQD |
| Q9UBC2 | S672 | Sugiyama | EPS15L1 EPS15R | ttstDPFGGDPFKESDPFRGsAtDDFFKKQTKNDPFTSDPF |
| Q9UBR2 | S78 | Sugiyama | CTSZ | SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UI15 | T190 | Sugiyama | TAGLN3 NP25 | GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________ |
| Q9ULC3 | S186 | Sugiyama | RAB23 HSPC137 | AEKYLQKLKQQIAEDPELTHsssNKIGVFNtsGGsHsGQNs |
| Q9UMY4 | S114 | Sugiyama | SNX12 | PGKALKRQLPFRGDEGIFEEsFIEERRQGLEQFINKIAGHP |
| Q9UNF0 | S273 | Sugiyama | PACSIN2 | KHLDLSNVAGYKAIyHDLEQsIRAADAVEDLRWFRANHGPG |
| Q9UNX3 | S9 | Sugiyama | RPL26L1 RPL26P1 | ____________MKFNPFVtsDRsKNRKRHFNAPSHVRRKI |
| Q9UPQ0 | S907 | Sugiyama | LIMCH1 KIAA1102 | TRESDRLEEKGsLTEGALAHsGNPVSKGVHEDHQLDTEAGA |
| Q9UQE7 | S886 | Sugiyama | SMC3 BAM BMH CSPG6 SMC3L1 | LEAINKRVKDTMARSEDLDNsIDKTEAGIKELQKSMERWKN |
| Q9Y265 | S29 | Sugiyama | RUVBL1 INO80H NMP238 TIP49 TIP49A | TTKTQRIAsHSHVKGLGLDEsGLAKQAASGLVGQENAREAC |
| Q9Y285 | S199 | Sugiyama | FARSA FARS FARSL FARSLA | SAFSTsISKQETELsPEMIssGSWRDRPFKPYNFLAHGVLP |
| Q9Y2B0 | S115 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF |
| Q9Y2B0 | S178 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | NVKDKLCSKRtDLCDHALHIsHDEL________________ |
| Q9Y2B0 | S63 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2I7 | S1145 | Sugiyama | PIKFYVE KIAA0981 PIP5K3 | IQVLPSHELVSTRIAEHLGDsQSLGRMLADYRARGGRIQPK |
| Q9Y3F4 | S282 | Sugiyama | STRAP MAWD UNRIP | KGHFGPIHCVRFSPDGELyAsGSEDGTLRLWQTVVGKtyGL |
| Q9Y3U8 | S91 | Sugiyama | RPL36 | KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______ |
| Q9Y450 | S65 | Sugiyama | HBS1L HBS1 KIAA1038 | RDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCL |
| Q9Y597 | S602 | Sugiyama | KCTD3 | KDVGGPTEEELLKLLDQCDLstsRCAtPNIsPATSVVQHSH |
| Q9Y5X1 | S116 | Sugiyama | SNX9 SH3PX1 SH3PXD3A | SNNHQVGSGNDPWSAWSASKsGNWESsEGWGAQPEGAGAQR |
| Q9Y617 | S43 | Sugiyama | PSAT1 PSA | LEIQKELLDYKGVGIsVLEMsHRssDFAKIINNTENLVREL |
| Q9Y6D5 | S700 | Sugiyama | ARFGEF2 ARFGEP2 BIG2 | QFLHQEERLDSTQVGDFLGDsARFNKEVMYAYVDQLDFCEK |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 1 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 7.771561e-16 | 15.109 | 1 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 1.728617e-13 | 12.762 | 1 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 2.252543e-11 | 10.647 | 0 | 0 |
| M Phase | R-HSA-68886 | 4.114187e-11 | 10.386 | 1 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 4.977507e-11 | 10.303 | 1 | 1 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 2.757732e-10 | 9.559 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 2.757732e-10 | 9.559 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 6.447013e-10 | 9.191 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 8.052073e-10 | 9.094 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 9.856129e-10 | 9.006 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 9.548502e-10 | 9.020 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 4.674663e-09 | 8.330 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 4.907423e-09 | 8.309 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 9.039334e-09 | 8.044 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 1.251654e-08 | 7.903 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 7.203185e-08 | 7.142 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.759911e-07 | 6.755 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 3.033836e-07 | 6.518 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 5.232770e-07 | 6.281 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 5.562190e-07 | 6.255 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 6.764612e-07 | 6.170 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.535716e-06 | 5.814 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 2.278796e-06 | 5.642 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 3.057438e-06 | 5.515 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 4.746440e-06 | 5.324 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 2.049388e-05 | 4.688 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.975643e-05 | 4.704 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 2.385082e-05 | 4.622 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.759379e-05 | 4.559 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 3.434280e-05 | 4.464 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 3.434280e-05 | 4.464 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 3.913277e-05 | 4.407 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 3.913277e-05 | 4.407 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 3.913277e-05 | 4.407 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 4.444985e-05 | 4.352 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 4.623407e-05 | 4.335 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 6.557733e-05 | 4.183 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.289772e-04 | 3.889 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.551341e-04 | 3.809 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.741666e-04 | 3.759 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 2.078228e-04 | 3.682 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.055259e-04 | 3.687 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 2.662666e-04 | 3.575 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 2.721083e-04 | 3.565 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 2.789406e-04 | 3.554 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 3.311064e-04 | 3.480 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 3.006637e-04 | 3.522 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 3.118930e-04 | 3.506 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 3.167348e-04 | 3.499 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 3.273617e-04 | 3.485 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 4.006792e-04 | 3.397 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 4.006792e-04 | 3.397 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 4.006792e-04 | 3.397 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 4.006792e-04 | 3.397 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 3.829841e-04 | 3.417 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 3.762761e-04 | 3.424 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 3.787350e-04 | 3.422 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 4.211958e-04 | 3.376 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 4.321560e-04 | 3.364 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 4.321560e-04 | 3.364 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 4.653286e-04 | 3.332 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 4.679348e-04 | 3.330 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 4.943157e-04 | 3.306 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 5.956441e-04 | 3.225 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 6.386623e-04 | 3.195 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 6.460535e-04 | 3.190 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 6.461067e-04 | 3.190 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 7.055015e-04 | 3.152 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 6.809621e-04 | 3.167 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 7.251776e-04 | 3.140 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 7.820899e-04 | 3.107 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 8.197669e-04 | 3.086 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 9.071062e-04 | 3.042 | 0 | 0 |
| Kinesins | R-HSA-983189 | 9.177447e-04 | 3.037 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 9.425929e-04 | 3.026 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.008225e-03 | 2.996 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.008225e-03 | 2.996 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.071155e-03 | 2.970 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.289013e-03 | 2.890 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.306651e-03 | 2.884 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 1.372047e-03 | 2.863 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.300675e-03 | 2.886 | 1 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 1.377934e-03 | 2.861 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.431523e-03 | 2.844 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 1.464532e-03 | 2.834 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.470139e-03 | 2.833 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.713692e-03 | 2.766 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.738388e-03 | 2.760 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.769589e-03 | 2.752 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 2.074409e-03 | 2.683 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 2.074409e-03 | 2.683 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 2.074409e-03 | 2.683 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 2.074409e-03 | 2.683 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 2.158441e-03 | 2.666 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 1.913936e-03 | 2.718 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 2.108677e-03 | 2.676 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.314312e-03 | 2.636 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 2.464383e-03 | 2.608 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 2.474707e-03 | 2.606 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 2.538486e-03 | 2.595 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 2.571450e-03 | 2.590 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 2.841422e-03 | 2.546 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.771900e-03 | 2.557 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.778653e-03 | 2.556 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.927366e-03 | 2.534 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 3.085278e-03 | 2.511 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 3.459435e-03 | 2.461 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 3.676403e-03 | 2.435 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 3.685091e-03 | 2.434 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 3.809701e-03 | 2.419 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 3.897779e-03 | 2.409 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 4.113214e-03 | 2.386 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 3.993253e-03 | 2.399 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 4.121945e-03 | 2.385 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 4.129806e-03 | 2.384 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 4.129806e-03 | 2.384 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 4.129806e-03 | 2.384 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 4.450256e-03 | 2.352 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 4.450256e-03 | 2.352 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 4.909814e-03 | 2.309 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 4.992790e-03 | 2.302 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 5.183945e-03 | 2.285 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 5.357108e-03 | 2.271 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 5.359147e-03 | 2.271 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 5.769040e-03 | 2.239 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 6.370525e-03 | 2.196 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 7.349717e-03 | 2.134 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 8.061971e-03 | 2.094 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 8.061971e-03 | 2.094 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 7.936196e-03 | 2.100 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 7.698306e-03 | 2.114 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 8.061971e-03 | 2.094 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 8.061971e-03 | 2.094 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 8.472034e-03 | 2.072 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 8.611545e-03 | 2.065 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 8.664892e-03 | 2.062 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 8.774345e-03 | 2.057 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 8.944135e-03 | 2.048 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 9.075240e-03 | 2.042 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 9.201066e-03 | 2.036 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 9.201066e-03 | 2.036 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 9.535942e-03 | 2.021 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 9.535942e-03 | 2.021 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 9.882194e-03 | 2.005 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.049113e-02 | 1.979 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.056613e-02 | 1.976 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 1.099406e-02 | 1.959 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.197176e-02 | 1.922 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.217248e-02 | 1.915 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.217248e-02 | 1.915 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 1.217248e-02 | 1.915 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.250929e-02 | 1.903 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.273315e-02 | 1.895 | 1 | 0 |
| Heme signaling | R-HSA-9707616 | 1.298710e-02 | 1.886 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 1.300249e-02 | 1.886 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.325860e-02 | 1.878 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 1.389480e-02 | 1.857 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 1.628847e-02 | 1.788 | 0 | 0 |
| Signaling by RAS GAP mutants | R-HSA-9753510 | 1.628847e-02 | 1.788 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.594049e-02 | 1.797 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.533302e-02 | 1.814 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 1.530844e-02 | 1.815 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 1.530844e-02 | 1.815 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.523229e-02 | 1.817 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.603615e-02 | 1.795 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.641683e-02 | 1.785 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.758630e-02 | 1.755 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 1.759322e-02 | 1.755 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 2.028507e-02 | 1.693 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 2.028507e-02 | 1.693 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 2.028507e-02 | 1.693 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 2.028507e-02 | 1.693 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 2.028507e-02 | 1.693 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 2.028507e-02 | 1.693 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 2.028507e-02 | 1.693 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 1.899145e-02 | 1.721 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 1.899145e-02 | 1.721 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 1.899145e-02 | 1.721 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.899145e-02 | 1.721 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 1.899145e-02 | 1.721 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 1.899145e-02 | 1.721 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 1.899145e-02 | 1.721 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 1.910826e-02 | 1.719 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 1.910826e-02 | 1.719 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 2.028507e-02 | 1.693 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.967144e-02 | 1.706 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.028507e-02 | 1.693 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.822119e-02 | 1.739 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.035331e-02 | 1.691 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 2.170926e-02 | 1.663 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.171249e-02 | 1.663 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 2.209128e-02 | 1.656 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 2.209128e-02 | 1.656 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.209128e-02 | 1.656 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.209128e-02 | 1.656 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.218240e-02 | 1.654 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 2.218240e-02 | 1.654 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 2.261741e-02 | 1.646 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 2.261741e-02 | 1.646 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 2.261741e-02 | 1.646 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 2.326681e-02 | 1.633 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 2.326681e-02 | 1.633 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 2.525286e-02 | 1.598 | 1 | 1 |
| Nucleosome assembly | R-HSA-774815 | 2.544288e-02 | 1.594 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 2.544288e-02 | 1.594 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 2.594780e-02 | 1.586 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 2.497610e-02 | 1.602 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 2.463073e-02 | 1.609 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 2.323526e-02 | 1.634 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 2.525286e-02 | 1.598 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 2.544288e-02 | 1.594 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 2.499467e-02 | 1.602 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 2.622298e-02 | 1.581 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 2.631713e-02 | 1.580 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 2.657080e-02 | 1.576 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 2.704403e-02 | 1.568 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 2.761681e-02 | 1.559 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 2.817662e-02 | 1.550 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.817662e-02 | 1.550 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.817662e-02 | 1.550 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 2.835381e-02 | 1.547 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 2.835381e-02 | 1.547 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 2.888148e-02 | 1.539 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.890559e-02 | 1.539 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.890559e-02 | 1.539 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.890559e-02 | 1.539 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.890559e-02 | 1.539 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.890559e-02 | 1.539 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.890559e-02 | 1.539 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 2.890559e-02 | 1.539 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.890559e-02 | 1.539 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.890559e-02 | 1.539 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 2.919788e-02 | 1.535 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 2.919788e-02 | 1.535 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 3.200402e-02 | 1.495 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 3.200402e-02 | 1.495 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 2.982438e-02 | 1.525 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 3.416904e-02 | 1.466 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 3.010555e-02 | 1.521 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 3.174250e-02 | 1.498 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 3.271414e-02 | 1.485 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.099466e-02 | 1.509 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 3.380316e-02 | 1.471 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 3.416904e-02 | 1.466 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 3.416904e-02 | 1.466 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 3.120954e-02 | 1.506 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 3.155889e-02 | 1.501 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 3.120954e-02 | 1.506 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 3.201623e-02 | 1.495 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 3.316846e-02 | 1.479 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 3.502271e-02 | 1.456 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.591336e-02 | 1.445 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 3.616122e-02 | 1.442 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 3.738506e-02 | 1.427 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 3.837563e-02 | 1.416 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 3.885682e-02 | 1.411 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 3.894386e-02 | 1.410 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 3.894386e-02 | 1.410 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 3.894386e-02 | 1.410 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 3.894386e-02 | 1.410 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 3.894386e-02 | 1.410 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.547801e-02 | 1.342 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 4.414146e-02 | 1.355 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 4.414146e-02 | 1.355 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 4.414146e-02 | 1.355 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 4.130983e-02 | 1.384 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 4.130983e-02 | 1.384 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 4.130983e-02 | 1.384 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 4.130983e-02 | 1.384 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 4.130472e-02 | 1.384 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 4.130472e-02 | 1.384 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 4.430471e-02 | 1.354 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.430471e-02 | 1.354 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 4.134912e-02 | 1.384 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 4.732172e-02 | 1.325 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 4.732172e-02 | 1.325 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 4.364620e-02 | 1.360 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 4.364620e-02 | 1.360 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 4.939350e-02 | 1.306 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.939350e-02 | 1.306 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 4.709431e-02 | 1.327 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 4.706605e-02 | 1.327 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.939350e-02 | 1.306 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 4.523119e-02 | 1.345 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 4.523119e-02 | 1.345 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.939350e-02 | 1.306 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 4.547801e-02 | 1.342 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 4.547801e-02 | 1.342 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.364620e-02 | 1.360 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 4.547801e-02 | 1.342 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 4.306562e-02 | 1.366 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 4.130472e-02 | 1.384 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 4.216321e-02 | 1.375 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 4.130983e-02 | 1.384 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 4.934306e-02 | 1.307 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 4.714288e-02 | 1.327 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 4.939350e-02 | 1.306 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 4.130983e-02 | 1.384 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 4.130983e-02 | 1.384 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 4.364620e-02 | 1.360 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 4.959014e-02 | 1.305 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 4.959014e-02 | 1.305 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 4.959014e-02 | 1.305 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 5.055098e-02 | 1.296 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 5.055098e-02 | 1.296 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 5.110356e-02 | 1.292 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 5.110356e-02 | 1.292 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 5.110356e-02 | 1.292 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 5.190625e-02 | 1.285 | 0 | 0 |
| S Phase | R-HSA-69242 | 5.312117e-02 | 1.275 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 5.384822e-02 | 1.269 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 5.384822e-02 | 1.269 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 5.402756e-02 | 1.267 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 5.485329e-02 | 1.261 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 5.485329e-02 | 1.261 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 5.485329e-02 | 1.261 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 5.563167e-02 | 1.255 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 5.656101e-02 | 1.247 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 5.669079e-02 | 1.246 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 5.719927e-02 | 1.243 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 5.830814e-02 | 1.234 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 5.831619e-02 | 1.234 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 5.851580e-02 | 1.233 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 5.851580e-02 | 1.233 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 5.851580e-02 | 1.233 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 5.855294e-02 | 1.232 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 5.855294e-02 | 1.232 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 5.855294e-02 | 1.232 | 0 | 0 |
| Defective Base Excision Repair Associated with OGG1 | R-HSA-9656249 | 5.974445e-02 | 1.224 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 5.974445e-02 | 1.224 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 5.974445e-02 | 1.224 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 6.575567e-02 | 1.182 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 6.575567e-02 | 1.182 | 0 | 0 |
| IRS activation | R-HSA-74713 | 6.575567e-02 | 1.182 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 6.575567e-02 | 1.182 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 6.575567e-02 | 1.182 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 6.178443e-02 | 1.209 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 6.178443e-02 | 1.209 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 6.178443e-02 | 1.209 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 6.821492e-02 | 1.166 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 7.275246e-02 | 1.138 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 7.275246e-02 | 1.138 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 7.275246e-02 | 1.138 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 7.275246e-02 | 1.138 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 6.094277e-02 | 1.215 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 6.861644e-02 | 1.164 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 6.861644e-02 | 1.164 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 6.327412e-02 | 1.199 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 6.340989e-02 | 1.198 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 6.761907e-02 | 1.170 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 6.340989e-02 | 1.198 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 7.254874e-02 | 1.139 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 6.013090e-02 | 1.221 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 6.177166e-02 | 1.209 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 7.345383e-02 | 1.134 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 7.254874e-02 | 1.139 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 7.043263e-02 | 1.152 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 6.327412e-02 | 1.199 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 6.492857e-02 | 1.188 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 7.272667e-02 | 1.138 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 6.178443e-02 | 1.209 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 7.275246e-02 | 1.138 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 6.821492e-02 | 1.166 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 6.611422e-02 | 1.180 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 6.178443e-02 | 1.209 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 7.508124e-02 | 1.124 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 7.508124e-02 | 1.124 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 7.508124e-02 | 1.124 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 7.508124e-02 | 1.124 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 7.545223e-02 | 1.122 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 7.545223e-02 | 1.122 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 7.545223e-02 | 1.122 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 7.545223e-02 | 1.122 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 7.552100e-02 | 1.122 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 7.552100e-02 | 1.122 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 7.552100e-02 | 1.122 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 7.552100e-02 | 1.122 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 7.572766e-02 | 1.121 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 7.639131e-02 | 1.117 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 7.687705e-02 | 1.114 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 7.693061e-02 | 1.114 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 7.739932e-02 | 1.111 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 7.964454e-02 | 1.099 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 8.288575e-02 | 1.082 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 8.288575e-02 | 1.082 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 8.491564e-02 | 1.071 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 8.521813e-02 | 1.069 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 8.530883e-02 | 1.069 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 8.530883e-02 | 1.069 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.530883e-02 | 1.069 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 8.569593e-02 | 1.067 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 8.583724e-02 | 1.066 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 8.736304e-02 | 1.059 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 8.813747e-02 | 1.055 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 8.813747e-02 | 1.055 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 8.850721e-02 | 1.053 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 8.943763e-02 | 1.048 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 8.943763e-02 | 1.048 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 8.943763e-02 | 1.048 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 8.943763e-02 | 1.048 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 8.943763e-02 | 1.048 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 8.943763e-02 | 1.048 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 8.943763e-02 | 1.048 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 9.076902e-02 | 1.042 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 9.076902e-02 | 1.042 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 9.076902e-02 | 1.042 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 9.086725e-02 | 1.042 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 9.374266e-02 | 1.028 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 9.374266e-02 | 1.028 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 9.374266e-02 | 1.028 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 9.505642e-02 | 1.022 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 9.505642e-02 | 1.022 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.517379e-02 | 1.021 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 9.517379e-02 | 1.021 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 9.711030e-02 | 1.013 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 9.766547e-02 | 1.010 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 9.766547e-02 | 1.010 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 9.766547e-02 | 1.010 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.002708e-01 | 0.999 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.015245e-01 | 0.993 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 1.020670e-01 | 0.991 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.228679e-01 | 0.911 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 1.228679e-01 | 0.911 | 0 | 0 |
| Defective OGG1 Localization | R-HSA-9657050 | 1.228679e-01 | 0.911 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 1.228679e-01 | 0.911 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.228679e-01 | 0.911 | 0 | 0 |
| Defective OGG1 Substrate Binding | R-HSA-9656255 | 1.228679e-01 | 0.911 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 1.161221e-01 | 0.935 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 1.161221e-01 | 0.935 | 1 | 1 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.143646e-01 | 0.942 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 1.367802e-01 | 0.864 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.255652e-01 | 0.901 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.255652e-01 | 0.901 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 1.255652e-01 | 0.901 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 1.142543e-01 | 0.942 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 1.035970e-01 | 0.985 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.317595e-01 | 0.880 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 1.158285e-01 | 0.936 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 1.158285e-01 | 0.936 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 1.158285e-01 | 0.936 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.241235e-01 | 0.906 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 1.350171e-01 | 0.870 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.142167e-01 | 0.942 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.276152e-01 | 0.894 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 1.303622e-01 | 0.885 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.055124e-01 | 0.977 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.136919e-01 | 0.944 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 1.074749e-01 | 0.969 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 1.301810e-01 | 0.885 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.172374e-01 | 0.931 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 1.161221e-01 | 0.935 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 1.312051e-01 | 0.882 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 1.085208e-01 | 0.964 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.367802e-01 | 0.864 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 1.142543e-01 | 0.942 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.278110e-01 | 0.893 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 1.054037e-01 | 0.977 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.124506e-01 | 0.949 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.347841e-01 | 0.870 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.282472e-01 | 0.892 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 1.035970e-01 | 0.985 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 1.319908e-01 | 0.879 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.361885e-01 | 0.866 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 1.074749e-01 | 0.969 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.172374e-01 | 0.931 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 1.255652e-01 | 0.901 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 1.387831e-01 | 0.858 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 1.404644e-01 | 0.852 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 1.404644e-01 | 0.852 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.404644e-01 | 0.852 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 1.404644e-01 | 0.852 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 1.404644e-01 | 0.852 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 1.404644e-01 | 0.852 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 1.404644e-01 | 0.852 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 1.404644e-01 | 0.852 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 1.416780e-01 | 0.849 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 1.436526e-01 | 0.843 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 1.449494e-01 | 0.839 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 1.449494e-01 | 0.839 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.451496e-01 | 0.838 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 1.451496e-01 | 0.838 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 1.451496e-01 | 0.838 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.451496e-01 | 0.838 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 1.451496e-01 | 0.838 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 1.453637e-01 | 0.838 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.453637e-01 | 0.838 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 1.453637e-01 | 0.838 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 1.453637e-01 | 0.838 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 1.453637e-01 | 0.838 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.510906e-01 | 0.821 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.527113e-01 | 0.816 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.527113e-01 | 0.816 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.535131e-01 | 0.814 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 1.536280e-01 | 0.814 | 0 | 0 |
| Defective OGG1 Substrate Processing | R-HSA-9656256 | 2.306455e-01 | 0.637 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.306455e-01 | 0.637 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 2.306455e-01 | 0.637 | 0 | 0 |
| TGFBR2 MSI Frameshift Mutants in Cancer | R-HSA-3642279 | 2.306455e-01 | 0.637 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 2.306455e-01 | 0.637 | 0 | 0 |
| Impaired BRCA2 binding to SEM1 (DSS1) | R-HSA-9763198 | 2.306455e-01 | 0.637 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 2.306455e-01 | 0.637 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 2.306455e-01 | 0.637 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 2.306455e-01 | 0.637 | 0 | 0 |
| Impaired BRCA2 translocation to the nucleus | R-HSA-9709275 | 2.306455e-01 | 0.637 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 2.306455e-01 | 0.637 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 2.306455e-01 | 0.637 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.863713e-01 | 0.730 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.863713e-01 | 0.730 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.863713e-01 | 0.730 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.863713e-01 | 0.730 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 1.863713e-01 | 0.730 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 1.863713e-01 | 0.730 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 1.863713e-01 | 0.730 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 1.863713e-01 | 0.730 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 3.251855e-01 | 0.488 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 3.251855e-01 | 0.488 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 3.251855e-01 | 0.488 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 3.251855e-01 | 0.488 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 3.251855e-01 | 0.488 | 0 | 0 |
| Defective HK1 causes hexokinase deficiency (HK deficiency) | R-HSA-5619056 | 3.251855e-01 | 0.488 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 3.251855e-01 | 0.488 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 3.251855e-01 | 0.488 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 3.251855e-01 | 0.488 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.251855e-01 | 0.488 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 3.251855e-01 | 0.488 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 3.251855e-01 | 0.488 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.251855e-01 | 0.488 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.251855e-01 | 0.488 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 3.251855e-01 | 0.488 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 3.251855e-01 | 0.488 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 3.251855e-01 | 0.488 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 2.339772e-01 | 0.631 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 2.339772e-01 | 0.631 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 2.339772e-01 | 0.631 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.339772e-01 | 0.631 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 2.339772e-01 | 0.631 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 2.339772e-01 | 0.631 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 2.339772e-01 | 0.631 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 2.339772e-01 | 0.631 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 2.339772e-01 | 0.631 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 1.767014e-01 | 0.753 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.096788e-01 | 0.678 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 2.096788e-01 | 0.678 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 2.096788e-01 | 0.678 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 2.821723e-01 | 0.549 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 4.081130e-01 | 0.389 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 4.081130e-01 | 0.389 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 4.081130e-01 | 0.389 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 4.081130e-01 | 0.389 | 0 | 0 |
| Defective visual phototransduction due to STRA6 loss of function | R-HSA-9918449 | 4.081130e-01 | 0.389 | 0 | 0 |
| Defective SLC12A1 causes Bartter syndrome 1 (BS1) | R-HSA-5619104 | 4.081130e-01 | 0.389 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 4.081130e-01 | 0.389 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 4.081130e-01 | 0.389 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 4.081130e-01 | 0.389 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 4.081130e-01 | 0.389 | 0 | 0 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 | R-HSA-5083633 | 4.081130e-01 | 0.389 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 4.081130e-01 | 0.389 | 0 | 0 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 | R-HSA-5083629 | 4.081130e-01 | 0.389 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 4.081130e-01 | 0.389 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 4.081130e-01 | 0.389 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 1.862175e-01 | 0.730 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 2.438587e-01 | 0.613 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 2.438587e-01 | 0.613 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 2.438587e-01 | 0.613 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 2.128200e-01 | 0.672 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 3.300934e-01 | 0.481 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 3.300934e-01 | 0.481 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 3.300934e-01 | 0.481 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 3.300934e-01 | 0.481 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 3.300934e-01 | 0.481 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.871703e-01 | 0.728 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 1.655724e-01 | 0.781 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 2.788325e-01 | 0.555 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 2.403902e-01 | 0.619 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.403902e-01 | 0.619 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 2.403902e-01 | 0.619 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.403902e-01 | 0.619 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 2.097682e-01 | 0.678 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 1.632970e-01 | 0.787 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 1.632970e-01 | 0.787 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 1.802204e-01 | 0.744 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 2.043051e-01 | 0.690 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 2.331879e-01 | 0.632 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 2.687135e-01 | 0.571 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 3.142267e-01 | 0.503 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 3.142267e-01 | 0.503 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 3.142267e-01 | 0.503 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 3.770805e-01 | 0.424 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 3.770805e-01 | 0.424 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 3.770805e-01 | 0.424 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 3.770805e-01 | 0.424 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 3.770805e-01 | 0.424 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 3.770805e-01 | 0.424 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 3.770805e-01 | 0.424 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.572976e-01 | 0.590 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 2.975814e-01 | 0.526 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 1.639283e-01 | 0.785 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 3.497059e-01 | 0.456 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 3.497059e-01 | 0.456 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 3.497059e-01 | 0.456 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 3.497059e-01 | 0.456 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 3.497059e-01 | 0.456 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 2.075046e-01 | 0.683 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 2.819652e-01 | 0.550 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.641760e-01 | 0.785 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 2.675676e-01 | 0.573 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 3.267945e-01 | 0.486 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 3.267945e-01 | 0.486 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 3.267945e-01 | 0.486 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 4.226399e-01 | 0.374 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 4.226399e-01 | 0.374 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 4.226399e-01 | 0.374 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 4.226399e-01 | 0.374 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 4.226399e-01 | 0.374 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.834102e-01 | 0.737 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 2.146936e-01 | 0.668 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 3.070601e-01 | 0.513 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.966294e-01 | 0.706 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 3.849746e-01 | 0.415 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 3.849746e-01 | 0.415 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 2.741112e-01 | 0.562 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 3.561652e-01 | 0.448 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 3.561652e-01 | 0.448 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 3.324547e-01 | 0.478 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 3.324547e-01 | 0.478 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 2.242674e-01 | 0.649 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 1.955679e-01 | 0.709 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 2.783506e-01 | 0.555 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 2.810681e-01 | 0.551 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 3.855197e-01 | 0.414 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 3.855197e-01 | 0.414 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 3.855197e-01 | 0.414 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 4.197765e-01 | 0.377 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 4.664131e-01 | 0.331 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 4.664131e-01 | 0.331 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 4.664131e-01 | 0.331 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 4.664131e-01 | 0.331 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 3.355370e-01 | 0.474 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 3.836571e-01 | 0.416 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 4.146985e-01 | 0.382 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.688424e-01 | 0.773 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 2.700560e-01 | 0.569 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 4.538936e-01 | 0.343 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 4.538936e-01 | 0.343 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 2.980158e-01 | 0.526 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 3.326322e-01 | 0.478 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 4.092374e-01 | 0.388 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 4.435577e-01 | 0.353 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.357916e-01 | 0.474 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 3.596479e-01 | 0.444 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 3.596479e-01 | 0.444 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 4.267786e-01 | 0.370 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 4.130833e-01 | 0.384 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 4.495979e-01 | 0.347 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 3.288968e-01 | 0.483 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.991485e-01 | 0.701 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 3.832673e-01 | 0.416 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 3.832673e-01 | 0.416 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 2.942967e-01 | 0.531 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.577901e-01 | 0.446 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.760583e-01 | 0.754 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.835065e-01 | 0.547 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 4.196408e-01 | 0.377 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 4.196408e-01 | 0.377 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 2.701910e-01 | 0.568 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 3.849746e-01 | 0.415 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 3.162028e-01 | 0.500 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 4.451920e-01 | 0.351 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.593857e-01 | 0.798 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.839827e-01 | 0.547 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.828535e-01 | 0.548 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 2.459093e-01 | 0.609 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 3.934319e-01 | 0.405 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.845971e-01 | 0.734 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 3.761218e-01 | 0.425 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 4.664131e-01 | 0.331 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 4.038213e-01 | 0.394 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 3.774901e-01 | 0.423 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 2.128200e-01 | 0.672 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 3.142267e-01 | 0.503 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 2.572976e-01 | 0.590 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 3.451307e-01 | 0.462 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 4.324356e-01 | 0.364 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 1.910060e-01 | 0.719 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 4.226399e-01 | 0.374 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 4.196408e-01 | 0.377 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 1.750865e-01 | 0.757 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.695759e-01 | 0.771 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 2.242674e-01 | 0.649 | 0 | 0 |
| Protein folding | R-HSA-391251 | 3.630637e-01 | 0.440 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 2.403902e-01 | 0.619 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 3.855197e-01 | 0.414 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 2.153120e-01 | 0.667 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.911456e-01 | 0.536 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 2.349492e-01 | 0.629 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 4.598425e-01 | 0.337 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 2.543062e-01 | 0.595 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 1.862175e-01 | 0.730 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.770805e-01 | 0.424 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 3.770805e-01 | 0.424 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 2.783506e-01 | 0.555 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 2.683503e-01 | 0.571 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 1.968683e-01 | 0.706 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.428498e-01 | 0.465 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 4.241747e-01 | 0.372 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.596479e-01 | 0.444 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 4.333815e-01 | 0.363 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 2.033838e-01 | 0.692 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 3.894730e-01 | 0.410 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 1.655724e-01 | 0.781 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 3.564574e-01 | 0.448 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 3.147945e-01 | 0.502 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.835534e-01 | 0.736 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 4.226399e-01 | 0.374 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 2.564735e-01 | 0.591 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 2.788325e-01 | 0.555 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 1.863713e-01 | 0.730 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 1.871703e-01 | 0.728 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 1.802204e-01 | 0.744 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 2.247917e-01 | 0.648 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 2.975814e-01 | 0.526 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 2.675676e-01 | 0.573 | 0 | 0 |
| PKA activation | R-HSA-163615 | 3.561652e-01 | 0.448 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.668496e-01 | 0.778 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 3.855197e-01 | 0.414 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 2.451029e-01 | 0.611 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 3.153520e-01 | 0.501 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 2.582931e-01 | 0.588 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 2.065058e-01 | 0.685 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 1.750865e-01 | 0.757 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 2.788325e-01 | 0.555 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 4.495979e-01 | 0.347 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.772754e-01 | 0.751 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 2.161066e-01 | 0.665 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 2.201265e-01 | 0.657 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 2.136639e-01 | 0.670 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 1.706206e-01 | 0.768 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.572976e-01 | 0.590 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 2.783506e-01 | 0.555 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 2.783506e-01 | 0.555 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 3.671826e-01 | 0.435 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.923320e-01 | 0.716 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 3.326322e-01 | 0.478 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 2.744667e-01 | 0.562 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 1.597882e-01 | 0.796 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 3.848542e-01 | 0.415 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 3.848542e-01 | 0.415 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 3.164388e-01 | 0.500 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 2.128200e-01 | 0.672 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 1.632970e-01 | 0.787 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 3.142267e-01 | 0.503 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 3.770805e-01 | 0.424 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 2.975814e-01 | 0.526 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 1.760583e-01 | 0.754 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 1.760583e-01 | 0.754 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 4.664131e-01 | 0.331 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 2.033838e-01 | 0.692 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 4.216601e-01 | 0.375 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 4.216601e-01 | 0.375 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 1.933441e-01 | 0.714 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 1.933441e-01 | 0.714 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 2.010123e-01 | 0.697 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 3.060000e-01 | 0.514 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 1.691519e-01 | 0.772 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 4.603600e-01 | 0.337 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 1.933441e-01 | 0.714 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.941101e-01 | 0.531 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.687135e-01 | 0.571 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 2.970229e-01 | 0.527 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 2.836365e-01 | 0.547 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 2.836365e-01 | 0.547 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 2.836365e-01 | 0.547 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 2.836365e-01 | 0.547 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 2.128200e-01 | 0.672 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 3.142267e-01 | 0.503 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 3.070601e-01 | 0.513 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 3.159746e-01 | 0.500 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 2.350500e-01 | 0.629 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 3.288968e-01 | 0.483 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 4.012862e-01 | 0.397 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 4.436119e-01 | 0.353 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.786458e-01 | 0.748 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 4.390136e-01 | 0.358 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.617723e-01 | 0.791 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 3.710116e-01 | 0.431 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 3.036908e-01 | 0.518 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 2.096788e-01 | 0.678 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 2.438587e-01 | 0.613 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.802204e-01 | 0.744 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 4.615649e-01 | 0.336 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 3.545039e-01 | 0.450 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 2.403902e-01 | 0.619 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 3.149234e-01 | 0.502 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 4.358905e-01 | 0.361 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.596479e-01 | 0.444 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 3.935196e-01 | 0.405 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 2.595167e-01 | 0.586 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 1.638685e-01 | 0.786 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 3.442089e-01 | 0.463 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 2.543062e-01 | 0.595 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 3.251855e-01 | 0.488 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.251855e-01 | 0.488 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 2.339772e-01 | 0.631 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.339772e-01 | 0.631 | 0 | 0 |
| Proton/oligopeptide cotransporters | R-HSA-427975 | 2.821723e-01 | 0.549 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 4.081130e-01 | 0.389 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 3.142267e-01 | 0.503 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 3.142267e-01 | 0.503 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 3.770805e-01 | 0.424 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 3.770805e-01 | 0.424 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 2.572976e-01 | 0.590 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.497059e-01 | 0.456 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 2.819652e-01 | 0.550 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.675676e-01 | 0.573 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 3.121414e-01 | 0.506 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 2.639249e-01 | 0.579 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 2.533413e-01 | 0.596 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 3.580261e-01 | 0.446 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 3.580261e-01 | 0.446 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 3.580261e-01 | 0.446 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 4.664131e-01 | 0.331 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 4.664131e-01 | 0.331 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.991708e-01 | 0.524 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 4.092374e-01 | 0.388 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 4.346641e-01 | 0.362 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 3.782017e-01 | 0.422 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.064655e-01 | 0.391 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 4.460115e-01 | 0.351 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 2.701910e-01 | 0.568 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 4.185935e-01 | 0.378 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 2.456646e-01 | 0.610 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 2.810681e-01 | 0.551 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 1.632970e-01 | 0.787 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 3.849746e-01 | 0.415 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 3.123183e-01 | 0.505 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.331879e-01 | 0.632 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 2.970229e-01 | 0.527 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 2.788325e-01 | 0.555 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 3.849746e-01 | 0.415 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 4.538936e-01 | 0.343 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 2.140483e-01 | 0.669 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 3.386025e-01 | 0.470 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 4.531449e-01 | 0.344 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.146936e-01 | 0.668 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 4.598425e-01 | 0.337 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 2.097682e-01 | 0.678 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 2.247917e-01 | 0.648 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 2.075046e-01 | 0.683 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 2.821723e-01 | 0.549 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 3.770805e-01 | 0.424 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.772754e-01 | 0.751 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 4.664131e-01 | 0.331 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 3.807992e-01 | 0.419 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 3.935196e-01 | 0.405 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 1.955679e-01 | 0.709 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 4.197765e-01 | 0.377 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 2.741112e-01 | 0.562 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.848542e-01 | 0.415 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 3.855197e-01 | 0.414 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 2.058589e-01 | 0.686 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 3.355370e-01 | 0.474 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 3.859417e-01 | 0.413 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.251855e-01 | 0.488 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 2.339772e-01 | 0.631 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 2.821723e-01 | 0.549 | 0 | 0 |
| SLC-mediated transport of oligopeptides | R-HSA-9959399 | 3.770805e-01 | 0.424 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 2.819652e-01 | 0.550 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 4.226399e-01 | 0.374 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 3.070601e-01 | 0.513 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 4.664131e-01 | 0.331 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 3.355370e-01 | 0.474 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 2.836365e-01 | 0.547 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 3.836571e-01 | 0.416 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 4.346641e-01 | 0.362 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 4.598425e-01 | 0.337 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 2.140483e-01 | 0.669 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 2.151957e-01 | 0.667 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 4.456446e-01 | 0.351 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 3.849746e-01 | 0.415 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 4.435577e-01 | 0.353 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.045064e-01 | 0.689 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 3.545039e-01 | 0.450 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 4.358905e-01 | 0.361 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.538936e-01 | 0.343 | 0 | 0 |
| Diseases of Base Excision Repair | R-HSA-9605308 | 2.821723e-01 | 0.549 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.855197e-01 | 0.414 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 1.863713e-01 | 0.730 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 2.339772e-01 | 0.631 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.840980e-01 | 0.735 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 3.267945e-01 | 0.486 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 4.226399e-01 | 0.374 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 3.324547e-01 | 0.478 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 4.664131e-01 | 0.331 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 4.038213e-01 | 0.394 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 4.346641e-01 | 0.362 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 3.561614e-01 | 0.448 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 3.739766e-01 | 0.427 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 3.267945e-01 | 0.486 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 4.664131e-01 | 0.331 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 4.664131e-01 | 0.331 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 4.495979e-01 | 0.347 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.556134e-01 | 0.808 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 2.942967e-01 | 0.531 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 4.664131e-01 | 0.331 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 4.538936e-01 | 0.343 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 3.326322e-01 | 0.478 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 3.561652e-01 | 0.448 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 4.668422e-01 | 0.331 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 4.703255e-01 | 0.328 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 4.703255e-01 | 0.328 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 4.714281e-01 | 0.327 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 4.714281e-01 | 0.327 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 4.714281e-01 | 0.327 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 4.714281e-01 | 0.327 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 4.719692e-01 | 0.326 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 4.719692e-01 | 0.326 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 4.719692e-01 | 0.326 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 4.722107e-01 | 0.326 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 4.724944e-01 | 0.326 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 4.759520e-01 | 0.322 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 4.778648e-01 | 0.321 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 4.799369e-01 | 0.319 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 4.800172e-01 | 0.319 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 4.808538e-01 | 0.318 | 0 | 0 |
| Activation of Na-permeable kainate receptors | R-HSA-451307 | 4.808538e-01 | 0.318 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 4.808538e-01 | 0.318 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 4.808538e-01 | 0.318 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 4.808538e-01 | 0.318 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 4.808538e-01 | 0.318 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 4.808538e-01 | 0.318 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 4.808538e-01 | 0.318 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 4.808538e-01 | 0.318 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 4.810633e-01 | 0.318 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 4.818868e-01 | 0.317 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 4.822039e-01 | 0.317 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 4.822039e-01 | 0.317 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 4.846499e-01 | 0.315 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 4.846858e-01 | 0.315 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 4.846858e-01 | 0.315 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 4.846858e-01 | 0.315 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 4.871437e-01 | 0.312 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 4.871437e-01 | 0.312 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 4.871437e-01 | 0.312 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 4.871437e-01 | 0.312 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 4.871437e-01 | 0.312 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 4.871437e-01 | 0.312 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 4.871437e-01 | 0.312 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.871437e-01 | 0.312 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 4.871437e-01 | 0.312 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 4.880610e-01 | 0.312 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 4.893591e-01 | 0.310 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 4.906148e-01 | 0.309 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 4.940662e-01 | 0.306 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 4.945537e-01 | 0.306 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 4.945537e-01 | 0.306 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 4.965016e-01 | 0.304 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 4.979006e-01 | 0.303 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 4.998202e-01 | 0.301 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.998202e-01 | 0.301 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 4.998202e-01 | 0.301 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 4.998202e-01 | 0.301 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 4.998202e-01 | 0.301 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 4.998202e-01 | 0.301 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 5.026695e-01 | 0.299 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 5.081510e-01 | 0.294 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 5.081510e-01 | 0.294 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 5.081510e-01 | 0.294 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 5.081510e-01 | 0.294 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 5.081510e-01 | 0.294 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 5.081510e-01 | 0.294 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 5.091163e-01 | 0.293 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 5.091163e-01 | 0.293 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 5.101449e-01 | 0.292 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 5.107008e-01 | 0.292 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 5.165690e-01 | 0.287 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 5.193785e-01 | 0.285 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 5.193785e-01 | 0.285 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 5.193785e-01 | 0.285 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 5.193785e-01 | 0.285 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 5.193785e-01 | 0.285 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 5.193785e-01 | 0.285 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 5.193785e-01 | 0.285 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 5.231024e-01 | 0.281 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 5.270135e-01 | 0.278 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 5.283579e-01 | 0.277 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 5.382039e-01 | 0.269 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 5.382039e-01 | 0.269 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 5.395975e-01 | 0.268 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 5.427409e-01 | 0.265 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 5.436632e-01 | 0.265 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 5.446587e-01 | 0.264 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 5.446587e-01 | 0.264 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 5.446587e-01 | 0.264 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 5.446587e-01 | 0.264 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 5.446587e-01 | 0.264 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.446587e-01 | 0.264 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 5.446587e-01 | 0.264 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 5.446587e-01 | 0.264 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 5.446587e-01 | 0.264 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 5.446587e-01 | 0.264 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 5.446587e-01 | 0.264 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 5.446587e-01 | 0.264 | 0 | 0 |
| Electric Transmission Across Gap Junctions | R-HSA-112303 | 5.446587e-01 | 0.264 | 0 | 0 |
| Transmission across Electrical Synapses | R-HSA-112307 | 5.446587e-01 | 0.264 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 5.468439e-01 | 0.262 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 5.476930e-01 | 0.261 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 5.476930e-01 | 0.261 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 5.476930e-01 | 0.261 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 5.476930e-01 | 0.261 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 5.476930e-01 | 0.261 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 5.493113e-01 | 0.260 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 5.504799e-01 | 0.259 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 5.504799e-01 | 0.259 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 5.506157e-01 | 0.259 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 5.506157e-01 | 0.259 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 5.534665e-01 | 0.257 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 5.534665e-01 | 0.257 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 5.534665e-01 | 0.257 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 5.541245e-01 | 0.256 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 5.594112e-01 | 0.252 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 5.594112e-01 | 0.252 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 5.622674e-01 | 0.250 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 5.622674e-01 | 0.250 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 5.622674e-01 | 0.250 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 5.622674e-01 | 0.250 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 5.634904e-01 | 0.249 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 5.639066e-01 | 0.249 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 5.677014e-01 | 0.246 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 5.677014e-01 | 0.246 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 5.702847e-01 | 0.244 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.702847e-01 | 0.244 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 5.727859e-01 | 0.242 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 5.748121e-01 | 0.240 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 5.752105e-01 | 0.240 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 5.791103e-01 | 0.237 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 5.792768e-01 | 0.237 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 5.792768e-01 | 0.237 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 5.801490e-01 | 0.236 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 5.803578e-01 | 0.236 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 5.803578e-01 | 0.236 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 5.803578e-01 | 0.236 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 5.814076e-01 | 0.236 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 5.814076e-01 | 0.236 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 5.828891e-01 | 0.234 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 5.845022e-01 | 0.233 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 5.849482e-01 | 0.233 | 0 | 0 |
| Scavenging by Class H Receptors | R-HSA-3000497 | 5.849482e-01 | 0.233 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 5.849482e-01 | 0.233 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 5.849482e-01 | 0.233 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 5.849482e-01 | 0.233 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 5.849482e-01 | 0.233 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 5.861929e-01 | 0.232 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 5.861929e-01 | 0.232 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 5.879275e-01 | 0.231 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 5.884278e-01 | 0.230 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 5.958904e-01 | 0.225 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 6.001312e-01 | 0.222 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 6.003807e-01 | 0.222 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 6.003807e-01 | 0.222 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 6.003943e-01 | 0.222 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 6.003943e-01 | 0.222 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 6.006251e-01 | 0.221 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 6.006251e-01 | 0.221 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 6.006251e-01 | 0.221 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 6.006251e-01 | 0.221 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 6.006251e-01 | 0.221 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 6.006251e-01 | 0.221 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 6.006251e-01 | 0.221 | 0 | 0 |
| Inositol transporters | R-HSA-429593 | 6.006251e-01 | 0.221 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 6.006251e-01 | 0.221 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 6.006251e-01 | 0.221 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 6.006251e-01 | 0.221 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 6.006251e-01 | 0.221 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 6.009963e-01 | 0.221 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 6.038896e-01 | 0.219 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 6.038896e-01 | 0.219 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 6.038896e-01 | 0.219 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 6.038896e-01 | 0.219 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 6.076870e-01 | 0.216 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 6.089469e-01 | 0.215 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 6.100147e-01 | 0.215 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 6.171636e-01 | 0.210 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 6.198815e-01 | 0.208 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 6.198815e-01 | 0.208 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 6.198815e-01 | 0.208 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 6.198815e-01 | 0.208 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 6.198815e-01 | 0.208 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 6.198815e-01 | 0.208 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 6.198815e-01 | 0.208 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 6.198815e-01 | 0.208 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 6.198815e-01 | 0.208 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 6.199912e-01 | 0.208 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 6.229318e-01 | 0.206 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 6.242263e-01 | 0.205 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 6.277608e-01 | 0.202 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 6.277608e-01 | 0.202 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 6.277608e-01 | 0.202 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 6.342553e-01 | 0.198 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 6.362034e-01 | 0.196 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 6.362252e-01 | 0.196 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 6.368610e-01 | 0.196 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 6.392046e-01 | 0.194 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 6.392046e-01 | 0.194 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 6.437113e-01 | 0.191 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 6.437113e-01 | 0.191 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 6.448725e-01 | 0.191 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 6.455425e-01 | 0.190 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.459183e-01 | 0.190 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 6.484494e-01 | 0.188 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 6.497154e-01 | 0.187 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.497154e-01 | 0.187 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.497154e-01 | 0.187 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.497154e-01 | 0.187 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 6.497154e-01 | 0.187 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 6.497154e-01 | 0.187 | 0 | 0 |
| Phase 1 - inactivation of fast Na+ channels | R-HSA-5576894 | 6.497154e-01 | 0.187 | 0 | 0 |
| Signaling by MST1 | R-HSA-8852405 | 6.497154e-01 | 0.187 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 6.497154e-01 | 0.187 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 6.497154e-01 | 0.187 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 6.497154e-01 | 0.187 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 6.497154e-01 | 0.187 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 6.497154e-01 | 0.187 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.505734e-01 | 0.187 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 6.506919e-01 | 0.187 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 6.506919e-01 | 0.187 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 6.507736e-01 | 0.187 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 6.515846e-01 | 0.186 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 6.525009e-01 | 0.185 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 6.525009e-01 | 0.185 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 6.525009e-01 | 0.185 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 6.525009e-01 | 0.185 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 6.525009e-01 | 0.185 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 6.525009e-01 | 0.185 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 6.525009e-01 | 0.185 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 6.525009e-01 | 0.185 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 6.566432e-01 | 0.183 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 6.566432e-01 | 0.183 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 6.566654e-01 | 0.183 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 6.621028e-01 | 0.179 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 6.621028e-01 | 0.179 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 6.621028e-01 | 0.179 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 6.621028e-01 | 0.179 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 6.621028e-01 | 0.179 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 6.635384e-01 | 0.178 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 6.664622e-01 | 0.176 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 6.664622e-01 | 0.176 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 6.701338e-01 | 0.174 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 6.703777e-01 | 0.174 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 6.703777e-01 | 0.174 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 6.703777e-01 | 0.174 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 6.726609e-01 | 0.172 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 6.726609e-01 | 0.172 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 6.753993e-01 | 0.170 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 6.756886e-01 | 0.170 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 6.771807e-01 | 0.169 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 6.792758e-01 | 0.168 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 6.828472e-01 | 0.166 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 6.828472e-01 | 0.166 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 6.828472e-01 | 0.166 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 6.828472e-01 | 0.166 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 6.841493e-01 | 0.165 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 6.866366e-01 | 0.163 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 6.866366e-01 | 0.163 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 6.866366e-01 | 0.163 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 6.866366e-01 | 0.163 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 6.866868e-01 | 0.163 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 6.866868e-01 | 0.163 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 6.925834e-01 | 0.160 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 6.925834e-01 | 0.160 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 6.927741e-01 | 0.159 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 6.927741e-01 | 0.159 | 0 | 0 |
| Chylomicron clearance | R-HSA-8964026 | 6.927741e-01 | 0.159 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 6.927741e-01 | 0.159 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 6.927741e-01 | 0.159 | 0 | 0 |
| Defective CHST3 causes SEDCJD | R-HSA-3595172 | 6.927741e-01 | 0.159 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 6.927741e-01 | 0.159 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 6.927741e-01 | 0.159 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 6.927741e-01 | 0.159 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 6.927741e-01 | 0.159 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 6.927741e-01 | 0.159 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 6.927741e-01 | 0.159 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 6.927741e-01 | 0.159 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 6.930122e-01 | 0.159 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 6.936548e-01 | 0.159 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 6.952270e-01 | 0.158 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 7.015938e-01 | 0.154 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 7.024699e-01 | 0.153 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 7.039407e-01 | 0.152 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.039407e-01 | 0.152 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 7.056854e-01 | 0.151 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 7.064545e-01 | 0.151 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 7.097099e-01 | 0.149 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.098106e-01 | 0.149 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.098106e-01 | 0.149 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 7.098106e-01 | 0.149 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 7.109864e-01 | 0.148 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 7.109864e-01 | 0.148 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 7.109864e-01 | 0.148 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 7.109864e-01 | 0.148 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 7.109864e-01 | 0.148 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 7.117769e-01 | 0.148 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 7.136691e-01 | 0.147 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 7.136691e-01 | 0.147 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 7.136691e-01 | 0.147 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 7.136691e-01 | 0.147 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 7.150411e-01 | 0.146 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 7.159625e-01 | 0.145 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 7.175069e-01 | 0.144 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 7.177195e-01 | 0.144 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 7.182095e-01 | 0.144 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 7.193642e-01 | 0.143 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 7.193642e-01 | 0.143 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 7.235051e-01 | 0.141 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 7.235051e-01 | 0.141 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 7.257759e-01 | 0.139 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 7.305421e-01 | 0.136 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.305421e-01 | 0.136 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 7.305421e-01 | 0.136 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 7.305421e-01 | 0.136 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 7.305421e-01 | 0.136 | 0 | 0 |
| Defective CHSY1 causes TPBS | R-HSA-3595177 | 7.305421e-01 | 0.136 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 7.305421e-01 | 0.136 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.305421e-01 | 0.136 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 7.305421e-01 | 0.136 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 7.305421e-01 | 0.136 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 7.305421e-01 | 0.136 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 7.305421e-01 | 0.136 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 7.305421e-01 | 0.136 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 7.305421e-01 | 0.136 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 7.305421e-01 | 0.136 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.316421e-01 | 0.136 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 7.316421e-01 | 0.136 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 7.316421e-01 | 0.136 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 7.327065e-01 | 0.135 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 7.327065e-01 | 0.135 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 7.330301e-01 | 0.135 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 7.370024e-01 | 0.133 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 7.370024e-01 | 0.133 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 7.370024e-01 | 0.133 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 7.391560e-01 | 0.131 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 7.395186e-01 | 0.131 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 7.395186e-01 | 0.131 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 7.412082e-01 | 0.130 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 7.413483e-01 | 0.130 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 7.413483e-01 | 0.130 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 7.413483e-01 | 0.130 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 7.428528e-01 | 0.129 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 7.507758e-01 | 0.124 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 7.521580e-01 | 0.124 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 7.521580e-01 | 0.124 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 7.521580e-01 | 0.124 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.521580e-01 | 0.124 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 7.609920e-01 | 0.119 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 7.609920e-01 | 0.119 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 7.609920e-01 | 0.119 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 7.609920e-01 | 0.119 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 7.609920e-01 | 0.119 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.609920e-01 | 0.119 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 7.609920e-01 | 0.119 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 7.619310e-01 | 0.118 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 7.636172e-01 | 0.117 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.636691e-01 | 0.117 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 7.636691e-01 | 0.117 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.636691e-01 | 0.117 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 7.636691e-01 | 0.117 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 7.636691e-01 | 0.117 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 7.636691e-01 | 0.117 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 7.636691e-01 | 0.117 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 7.636691e-01 | 0.117 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 7.636691e-01 | 0.117 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 7.636691e-01 | 0.117 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 7.636691e-01 | 0.117 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 7.636691e-01 | 0.117 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 7.636691e-01 | 0.117 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 7.636691e-01 | 0.117 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 7.636691e-01 | 0.117 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 7.678914e-01 | 0.115 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 7.678914e-01 | 0.115 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 7.678914e-01 | 0.115 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 7.680825e-01 | 0.115 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 7.697634e-01 | 0.114 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 7.703735e-01 | 0.113 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 7.713931e-01 | 0.113 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 7.713931e-01 | 0.113 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 7.713931e-01 | 0.113 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 7.713931e-01 | 0.113 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 7.796938e-01 | 0.108 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 7.828132e-01 | 0.106 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 7.828132e-01 | 0.106 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 7.830601e-01 | 0.106 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 7.830601e-01 | 0.106 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 7.840724e-01 | 0.106 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 7.840724e-01 | 0.106 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 7.845886e-01 | 0.105 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 7.845886e-01 | 0.105 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 7.893886e-01 | 0.103 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 7.893886e-01 | 0.103 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 7.898268e-01 | 0.102 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 7.927251e-01 | 0.101 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 7.927251e-01 | 0.101 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 7.927251e-01 | 0.101 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 7.927251e-01 | 0.101 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 7.927251e-01 | 0.101 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 7.927251e-01 | 0.101 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 7.927251e-01 | 0.101 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 7.927251e-01 | 0.101 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 7.927251e-01 | 0.101 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 7.927251e-01 | 0.101 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 7.927251e-01 | 0.101 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 7.993417e-01 | 0.097 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 8.000501e-01 | 0.097 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 8.018991e-01 | 0.096 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 8.033164e-01 | 0.095 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 8.033164e-01 | 0.095 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 8.033164e-01 | 0.095 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 8.035162e-01 | 0.095 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 8.061901e-01 | 0.094 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.061901e-01 | 0.094 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.089836e-01 | 0.092 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 8.100856e-01 | 0.091 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 8.108481e-01 | 0.091 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 8.137255e-01 | 0.090 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 8.182103e-01 | 0.087 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 8.182103e-01 | 0.087 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 8.182103e-01 | 0.087 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 8.182103e-01 | 0.087 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 8.182103e-01 | 0.087 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 8.182103e-01 | 0.087 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 8.182103e-01 | 0.087 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 8.182103e-01 | 0.087 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 8.182103e-01 | 0.087 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 8.182103e-01 | 0.087 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 8.182103e-01 | 0.087 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 8.182103e-01 | 0.087 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 8.182103e-01 | 0.087 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 8.182103e-01 | 0.087 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 8.218472e-01 | 0.085 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 8.218728e-01 | 0.085 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 8.218728e-01 | 0.085 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 8.218728e-01 | 0.085 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.218728e-01 | 0.085 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 8.218728e-01 | 0.085 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 8.218728e-01 | 0.085 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 8.226609e-01 | 0.085 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 8.226609e-01 | 0.085 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 8.226609e-01 | 0.085 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 8.226609e-01 | 0.085 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 8.226609e-01 | 0.085 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 8.226609e-01 | 0.085 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 8.226609e-01 | 0.085 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.229642e-01 | 0.085 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 8.246662e-01 | 0.084 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 8.269847e-01 | 0.083 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 8.272525e-01 | 0.082 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 8.272525e-01 | 0.082 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 8.272525e-01 | 0.082 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 8.307266e-01 | 0.081 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 8.335628e-01 | 0.079 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 8.350055e-01 | 0.078 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 8.354483e-01 | 0.078 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 8.364116e-01 | 0.078 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 8.375425e-01 | 0.077 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 8.388411e-01 | 0.076 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 8.388411e-01 | 0.076 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 8.388411e-01 | 0.076 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 8.388411e-01 | 0.076 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.388411e-01 | 0.076 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 8.388411e-01 | 0.076 | 0 | 0 |
| Depurination | R-HSA-73927 | 8.399534e-01 | 0.076 | 0 | 0 |
| DAG1 core M3 glycosylations | R-HSA-8932505 | 8.405633e-01 | 0.075 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 8.405633e-01 | 0.075 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 8.405633e-01 | 0.075 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 8.405633e-01 | 0.075 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 8.405633e-01 | 0.075 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 8.405633e-01 | 0.075 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 8.405633e-01 | 0.075 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 8.405633e-01 | 0.075 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 8.405633e-01 | 0.075 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 8.405633e-01 | 0.075 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 8.457875e-01 | 0.073 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 8.476538e-01 | 0.072 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 8.499367e-01 | 0.071 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 8.499367e-01 | 0.071 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 8.518607e-01 | 0.070 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 8.518607e-01 | 0.070 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 8.518607e-01 | 0.070 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 8.532261e-01 | 0.069 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 8.532261e-01 | 0.069 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 8.543311e-01 | 0.068 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 8.543311e-01 | 0.068 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 8.543311e-01 | 0.068 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 8.543311e-01 | 0.068 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 8.543311e-01 | 0.068 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 8.551179e-01 | 0.068 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 8.563823e-01 | 0.067 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 8.582467e-01 | 0.066 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 8.600607e-01 | 0.065 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 8.601689e-01 | 0.065 | 0 | 0 |
| Anchoring fibril formation | R-HSA-2214320 | 8.601689e-01 | 0.065 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 8.601689e-01 | 0.065 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 8.601689e-01 | 0.065 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.601689e-01 | 0.065 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 8.601689e-01 | 0.065 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 8.601689e-01 | 0.065 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 8.601689e-01 | 0.065 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 8.601689e-01 | 0.065 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.610567e-01 | 0.065 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 8.611559e-01 | 0.065 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 8.614584e-01 | 0.065 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 8.620264e-01 | 0.064 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 8.624767e-01 | 0.064 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 8.624767e-01 | 0.064 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 8.630076e-01 | 0.064 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 8.630076e-01 | 0.064 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 8.661469e-01 | 0.062 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 8.661469e-01 | 0.062 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.684497e-01 | 0.061 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.710265e-01 | 0.060 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 8.710265e-01 | 0.060 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 8.726037e-01 | 0.059 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 8.726037e-01 | 0.059 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 8.726037e-01 | 0.059 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 8.734280e-01 | 0.059 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 8.734280e-01 | 0.059 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 8.740857e-01 | 0.058 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 8.743075e-01 | 0.058 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 8.743075e-01 | 0.058 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 8.757509e-01 | 0.058 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 8.757509e-01 | 0.058 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 8.773647e-01 | 0.057 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 8.773647e-01 | 0.057 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 8.773647e-01 | 0.057 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 8.773647e-01 | 0.057 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.773647e-01 | 0.057 | 0 | 0 |
| Synthesis of GDP-mannose | R-HSA-446205 | 8.773647e-01 | 0.057 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 8.773647e-01 | 0.057 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 8.773647e-01 | 0.057 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.773647e-01 | 0.057 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 8.773647e-01 | 0.057 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 8.795311e-01 | 0.056 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 8.814802e-01 | 0.055 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 8.831564e-01 | 0.054 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 8.831564e-01 | 0.054 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 8.831564e-01 | 0.054 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 8.845726e-01 | 0.053 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 8.845726e-01 | 0.053 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 8.845726e-01 | 0.053 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 8.863737e-01 | 0.052 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 8.872563e-01 | 0.052 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 8.875585e-01 | 0.052 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 8.924466e-01 | 0.049 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.924466e-01 | 0.049 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 8.924466e-01 | 0.049 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.924466e-01 | 0.049 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 8.924466e-01 | 0.049 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.924466e-01 | 0.049 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 8.926578e-01 | 0.049 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.928520e-01 | 0.049 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 8.929802e-01 | 0.049 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 8.929802e-01 | 0.049 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 8.929802e-01 | 0.049 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 8.951275e-01 | 0.048 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 8.982994e-01 | 0.047 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 8.999506e-01 | 0.046 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.006739e-01 | 0.045 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 9.015540e-01 | 0.045 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 9.019501e-01 | 0.045 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.035143e-01 | 0.044 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.035837e-01 | 0.044 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.035837e-01 | 0.044 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 9.035837e-01 | 0.044 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 9.038595e-01 | 0.044 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.038595e-01 | 0.044 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.038595e-01 | 0.044 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 9.038595e-01 | 0.044 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 9.056746e-01 | 0.043 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 9.056746e-01 | 0.043 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 9.056746e-01 | 0.043 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 9.056746e-01 | 0.043 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 9.056746e-01 | 0.043 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 9.056746e-01 | 0.043 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 9.056746e-01 | 0.043 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 9.056746e-01 | 0.043 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 9.056746e-01 | 0.043 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 9.056746e-01 | 0.043 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.078814e-01 | 0.042 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 9.080016e-01 | 0.042 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.085306e-01 | 0.042 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.089834e-01 | 0.041 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.122711e-01 | 0.040 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.131987e-01 | 0.039 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.131987e-01 | 0.039 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.131987e-01 | 0.039 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.131987e-01 | 0.039 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.131987e-01 | 0.039 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.131987e-01 | 0.039 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.138252e-01 | 0.039 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.146799e-01 | 0.039 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.149844e-01 | 0.039 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 9.152707e-01 | 0.038 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.158301e-01 | 0.038 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 9.172763e-01 | 0.037 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 9.172763e-01 | 0.037 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 9.172763e-01 | 0.037 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 9.172763e-01 | 0.037 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 9.172763e-01 | 0.037 | 0 | 0 |
| Protein repair | R-HSA-5676934 | 9.172763e-01 | 0.037 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 9.172763e-01 | 0.037 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 9.172763e-01 | 0.037 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 9.172763e-01 | 0.037 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.173015e-01 | 0.037 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.200080e-01 | 0.036 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 9.210328e-01 | 0.036 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.210328e-01 | 0.036 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.219079e-01 | 0.035 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.219079e-01 | 0.035 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.242704e-01 | 0.034 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.256407e-01 | 0.034 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 9.271163e-01 | 0.033 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 9.271163e-01 | 0.033 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.271163e-01 | 0.033 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.271163e-01 | 0.033 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 9.274516e-01 | 0.033 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 9.274516e-01 | 0.033 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 9.274516e-01 | 0.033 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 9.274516e-01 | 0.033 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.274516e-01 | 0.033 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 9.274516e-01 | 0.033 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 9.274516e-01 | 0.033 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 9.274516e-01 | 0.033 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 9.274516e-01 | 0.033 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.275953e-01 | 0.033 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.297885e-01 | 0.032 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 9.316572e-01 | 0.031 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 9.316572e-01 | 0.031 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 9.319570e-01 | 0.031 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 9.353233e-01 | 0.029 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 9.355066e-01 | 0.029 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 9.363758e-01 | 0.029 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.363758e-01 | 0.029 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.363758e-01 | 0.029 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 9.363758e-01 | 0.029 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 9.363758e-01 | 0.029 | 0 | 0 |
| Vitamin B6 activation to pyridoxal phosphate | R-HSA-964975 | 9.363758e-01 | 0.029 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 9.363758e-01 | 0.029 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 9.363758e-01 | 0.029 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 9.363758e-01 | 0.029 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 9.363758e-01 | 0.029 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 9.363758e-01 | 0.029 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.369126e-01 | 0.028 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.369126e-01 | 0.028 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.369126e-01 | 0.028 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.369126e-01 | 0.028 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.369126e-01 | 0.028 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.372450e-01 | 0.028 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.376475e-01 | 0.028 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 9.379912e-01 | 0.028 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.381346e-01 | 0.028 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.396215e-01 | 0.027 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.396215e-01 | 0.027 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.400827e-01 | 0.027 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.424447e-01 | 0.026 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.424447e-01 | 0.026 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.424447e-01 | 0.026 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.433471e-01 | 0.025 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.433471e-01 | 0.025 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 9.442028e-01 | 0.025 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.442028e-01 | 0.025 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.442028e-01 | 0.025 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 9.442028e-01 | 0.025 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 9.442028e-01 | 0.025 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 9.442028e-01 | 0.025 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 9.442028e-01 | 0.025 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 9.442028e-01 | 0.025 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 9.442028e-01 | 0.025 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.451001e-01 | 0.025 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.458794e-01 | 0.024 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 9.469063e-01 | 0.024 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 9.491536e-01 | 0.023 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.491536e-01 | 0.023 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 9.492726e-01 | 0.023 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 9.494800e-01 | 0.023 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.501135e-01 | 0.022 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.501135e-01 | 0.022 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.501135e-01 | 0.022 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.502846e-01 | 0.022 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 9.503991e-01 | 0.022 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 9.510672e-01 | 0.022 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.510672e-01 | 0.022 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 9.510672e-01 | 0.022 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 9.510672e-01 | 0.022 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 9.538894e-01 | 0.021 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 9.543894e-01 | 0.020 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.546972e-01 | 0.020 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.546972e-01 | 0.020 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.546972e-01 | 0.020 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.570875e-01 | 0.019 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.570875e-01 | 0.019 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.588843e-01 | 0.018 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.588843e-01 | 0.018 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.588843e-01 | 0.018 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.588843e-01 | 0.018 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.590369e-01 | 0.018 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 9.591069e-01 | 0.018 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 9.613963e-01 | 0.017 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.623675e-01 | 0.017 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.623675e-01 | 0.017 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.623675e-01 | 0.017 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.627061e-01 | 0.017 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 9.633544e-01 | 0.016 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 9.633544e-01 | 0.016 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 9.633544e-01 | 0.016 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 9.644722e-01 | 0.016 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.661916e-01 | 0.015 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.669980e-01 | 0.015 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.669980e-01 | 0.015 | 0 | 0 |
| Abacavir metabolism | R-HSA-2161541 | 9.669980e-01 | 0.015 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.669980e-01 | 0.015 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 9.669980e-01 | 0.015 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.671761e-01 | 0.014 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.671761e-01 | 0.014 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.671761e-01 | 0.014 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.672534e-01 | 0.014 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.676884e-01 | 0.014 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.685057e-01 | 0.014 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.705557e-01 | 0.013 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 9.706124e-01 | 0.013 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.706124e-01 | 0.013 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.706124e-01 | 0.013 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.706124e-01 | 0.013 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.706124e-01 | 0.013 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.706124e-01 | 0.013 | 0 | 0 |
| CS-GAG biosynthesis | R-HSA-2022870 | 9.710590e-01 | 0.013 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 9.710590e-01 | 0.013 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.710590e-01 | 0.013 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.714669e-01 | 0.013 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.722606e-01 | 0.012 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 9.729113e-01 | 0.012 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.731207e-01 | 0.012 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.734312e-01 | 0.012 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.737003e-01 | 0.012 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.746205e-01 | 0.011 | 0 | 0 |
| Reactions specific to the complex N-glycan synthesis pathway | R-HSA-975578 | 9.746205e-01 | 0.011 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.746205e-01 | 0.011 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.746205e-01 | 0.011 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.754864e-01 | 0.011 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.764735e-01 | 0.010 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.764735e-01 | 0.010 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.777439e-01 | 0.010 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.777439e-01 | 0.010 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.777439e-01 | 0.010 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.777439e-01 | 0.010 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 9.778309e-01 | 0.010 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.787387e-01 | 0.009 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.789627e-01 | 0.009 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.790017e-01 | 0.009 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.795001e-01 | 0.009 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.798900e-01 | 0.009 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.798900e-01 | 0.009 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 9.804831e-01 | 0.009 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.804831e-01 | 0.009 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.811957e-01 | 0.008 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.811957e-01 | 0.008 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.818261e-01 | 0.008 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.823363e-01 | 0.008 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.824949e-01 | 0.008 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.828853e-01 | 0.007 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.828853e-01 | 0.007 | 0 | 0 |
| Retinoid cycle disease events | R-HSA-2453864 | 9.828853e-01 | 0.007 | 0 | 0 |
| Diseases associated with visual transduction | R-HSA-2474795 | 9.828853e-01 | 0.007 | 0 | 0 |
| Diseases of the neuronal system | R-HSA-9675143 | 9.828853e-01 | 0.007 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.831979e-01 | 0.007 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.832312e-01 | 0.007 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 9.838279e-01 | 0.007 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 9.843020e-01 | 0.007 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 9.843020e-01 | 0.007 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 9.846036e-01 | 0.007 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 9.848579e-01 | 0.007 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.849919e-01 | 0.007 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.849919e-01 | 0.007 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.849919e-01 | 0.007 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.849919e-01 | 0.007 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.849922e-01 | 0.007 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.849922e-01 | 0.007 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 9.850787e-01 | 0.007 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.854756e-01 | 0.006 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.862911e-01 | 0.006 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.863327e-01 | 0.006 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.865996e-01 | 0.006 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 9.868394e-01 | 0.006 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.868394e-01 | 0.006 | 0 | 0 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | R-HSA-83936 | 9.868394e-01 | 0.006 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 9.868394e-01 | 0.006 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 9.868394e-01 | 0.006 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.868394e-01 | 0.006 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 9.872451e-01 | 0.006 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.876269e-01 | 0.005 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.880387e-01 | 0.005 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.895085e-01 | 0.005 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 9.898803e-01 | 0.004 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.898803e-01 | 0.004 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.898803e-01 | 0.004 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.908533e-01 | 0.004 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 9.908842e-01 | 0.004 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.909655e-01 | 0.004 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 9.913534e-01 | 0.004 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.915094e-01 | 0.004 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.922188e-01 | 0.003 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.922535e-01 | 0.003 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.924248e-01 | 0.003 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.925777e-01 | 0.003 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.928852e-01 | 0.003 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.931769e-01 | 0.003 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.932535e-01 | 0.003 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.934030e-01 | 0.003 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 9.939236e-01 | 0.003 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.940171e-01 | 0.003 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.940171e-01 | 0.003 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.940636e-01 | 0.003 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.940636e-01 | 0.003 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.941050e-01 | 0.003 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.943994e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.946452e-01 | 0.002 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.946452e-01 | 0.002 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 9.947539e-01 | 0.002 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.947539e-01 | 0.002 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.947539e-01 | 0.002 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.947539e-01 | 0.002 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.954000e-01 | 0.002 | 0 | 0 |
| Phosphate bond hydrolysis by NUDT proteins | R-HSA-2393930 | 9.954000e-01 | 0.002 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.955478e-01 | 0.002 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.959665e-01 | 0.002 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.959665e-01 | 0.002 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 9.962206e-01 | 0.002 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.962206e-01 | 0.002 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 9.964633e-01 | 0.002 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.964633e-01 | 0.002 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.964633e-01 | 0.002 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.968697e-01 | 0.001 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.968989e-01 | 0.001 | 0 | 0 |
| Ubiquinol biosynthesis | R-HSA-2142789 | 9.968989e-01 | 0.001 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.968989e-01 | 0.001 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.968989e-01 | 0.001 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.970075e-01 | 0.001 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.972809e-01 | 0.001 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.974632e-01 | 0.001 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.976327e-01 | 0.001 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.976912e-01 | 0.001 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.978243e-01 | 0.001 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.979096e-01 | 0.001 | 0 | 0 |
| N-glycan antennae elongation in the medial/trans-Golgi | R-HSA-975576 | 9.979096e-01 | 0.001 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.979096e-01 | 0.001 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.979690e-01 | 0.001 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.979690e-01 | 0.001 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.981672e-01 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.982209e-01 | 0.001 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.982735e-01 | 0.001 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.983930e-01 | 0.001 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.984616e-01 | 0.001 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.985775e-01 | 0.001 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.986870e-01 | 0.001 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.986879e-01 | 0.001 | 0 | 0 |
| Translation | R-HSA-72766 | 9.987170e-01 | 0.001 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.987646e-01 | 0.001 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.987646e-01 | 0.001 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.987646e-01 | 0.001 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.987933e-01 | 0.001 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.988733e-01 | 0.000 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.989169e-01 | 0.000 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.990504e-01 | 0.000 | 0 | 0 |
| The canonical retinoid cycle in rods (twilight vision) | R-HSA-2453902 | 9.990504e-01 | 0.000 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.990504e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.991834e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.991834e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.992373e-01 | 0.000 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.992700e-01 | 0.000 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.992700e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.993051e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.993362e-01 | 0.000 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.993566e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.994291e-01 | 0.000 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.994389e-01 | 0.000 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.994389e-01 | 0.000 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.995081e-01 | 0.000 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.995687e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.995963e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.996014e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.996465e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.996465e-01 | 0.000 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.997094e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.997452e-01 | 0.000 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.997816e-01 | 0.000 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.998495e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.998495e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.998654e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.998843e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.998938e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.998944e-01 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.999004e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.999018e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.999111e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.999250e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999417e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.999540e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.999690e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999737e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999738e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.999762e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.999762e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999790e-01 | 0.000 | 0 | 0 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 9.999791e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.999817e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999843e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999861e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999862e-01 | 0.000 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.999877e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.999877e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999883e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999900e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999909e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999917e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999919e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999921e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999944e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999951e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.999954e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999959e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.999962e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999962e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999966e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999971e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999973e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999978e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999979e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999995e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999995e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999998e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999999e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999999e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999999e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999999e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999999e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999999e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 1.000000e+00 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | -0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 1 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.110223e-16 | 15.955 | 1 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.776357e-15 | 14.750 | 1 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 6.006307e-14 | 13.221 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 1.448841e-13 | 12.839 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.886269e-13 | 12.724 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 9.916512e-13 | 12.004 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.462275e-12 | 11.835 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 4.644951e-12 | 11.333 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.265987e-11 | 10.898 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.976364e-11 | 10.704 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 3.171940e-11 | 10.499 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 3.374312e-11 | 10.472 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 3.592260e-11 | 10.445 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.812861e-11 | 10.419 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.492573e-11 | 10.348 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 5.129608e-11 | 10.290 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 6.061263e-11 | 10.217 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 5.848610e-11 | 10.233 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 7.276846e-11 | 10.138 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 7.253609e-11 | 10.139 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 7.253609e-11 | 10.139 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 8.357692e-11 | 10.078 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 8.330769e-11 | 10.079 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 8.141587e-11 | 10.089 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 8.623413e-11 | 10.064 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 9.236256e-11 | 10.035 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.024912e-10 | 9.989 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.305781e-10 | 9.884 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.655402e-10 | 9.781 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.972111e-10 | 9.705 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 6.136025e-10 | 9.212 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 6.136025e-10 | 9.212 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 8.236961e-10 | 9.084 | 1 | 0 |
| Aggrephagy | R-HSA-9646399 | 8.839929e-10 | 9.054 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 9.786841e-10 | 9.009 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 2.213208e-09 | 8.655 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 2.290181e-09 | 8.640 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 2.447161e-09 | 8.611 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 2.956314e-09 | 8.529 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 2.906930e-09 | 8.537 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 3.112624e-09 | 8.507 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 4.921222e-09 | 8.308 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 5.293805e-09 | 8.276 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 6.791835e-09 | 8.168 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 7.289598e-09 | 8.137 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 8.921018e-09 | 8.050 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.076309e-08 | 7.968 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 1.483281e-08 | 7.829 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.783391e-08 | 7.749 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.914368e-08 | 7.718 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 2.114289e-08 | 7.675 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 2.274497e-08 | 7.643 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 3.085467e-08 | 7.511 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 3.485874e-08 | 7.458 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 3.709124e-08 | 7.431 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 3.595825e-08 | 7.444 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 3.977826e-08 | 7.400 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 3.940388e-08 | 7.404 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 4.330306e-08 | 7.363 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 5.736023e-08 | 7.241 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 5.787795e-08 | 7.237 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 6.045869e-08 | 7.219 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 7.604748e-08 | 7.119 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 8.128668e-08 | 7.090 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 8.338905e-08 | 7.079 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 1.103293e-07 | 6.957 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.136197e-07 | 6.945 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.350338e-07 | 6.870 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.065963e-07 | 6.685 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.065963e-07 | 6.685 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 2.336096e-07 | 6.632 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 2.367662e-07 | 6.626 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.518911e-07 | 6.599 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.477171e-07 | 6.606 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 2.875181e-07 | 6.541 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 2.875181e-07 | 6.541 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 2.900462e-07 | 6.538 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 3.094785e-07 | 6.509 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 3.480058e-07 | 6.458 | 1 | 1 |
| Macroautophagy | R-HSA-1632852 | 3.778347e-07 | 6.423 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 4.172365e-07 | 6.380 | 1 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 4.989041e-07 | 6.302 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 6.172208e-07 | 6.210 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 6.401784e-07 | 6.194 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 6.835091e-07 | 6.165 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 6.992025e-07 | 6.155 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 7.347269e-07 | 6.134 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 8.492807e-07 | 6.071 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 8.708822e-07 | 6.060 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 9.895498e-07 | 6.005 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 1.005586e-06 | 5.998 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.008143e-06 | 5.996 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.117468e-06 | 5.952 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.308794e-06 | 5.883 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 1.362264e-06 | 5.866 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 1.568117e-06 | 5.805 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 1.590312e-06 | 5.799 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.809559e-06 | 5.742 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 1.900313e-06 | 5.721 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 1.914130e-06 | 5.718 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.001136e-06 | 5.699 | 0 | 0 |
| Protein folding | R-HSA-391251 | 2.300392e-06 | 5.638 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 2.762755e-06 | 5.559 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 2.996948e-06 | 5.523 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 3.133007e-06 | 5.504 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 4.020580e-06 | 5.396 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 4.512567e-06 | 5.346 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 4.663065e-06 | 5.331 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 4.884227e-06 | 5.311 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 5.069247e-06 | 5.295 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 5.764871e-06 | 5.239 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 7.089671e-06 | 5.149 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 8.083176e-06 | 5.092 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 9.015710e-06 | 5.045 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 8.896460e-06 | 5.051 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.492962e-06 | 5.023 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 1.048558e-05 | 4.979 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.263139e-05 | 4.899 | 1 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.398652e-05 | 4.854 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 1.559074e-05 | 4.807 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.528508e-05 | 4.816 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.557576e-05 | 4.808 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.561772e-05 | 4.806 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 1.650894e-05 | 4.782 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.652989e-05 | 4.782 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.746140e-05 | 4.758 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.808361e-05 | 4.743 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.808361e-05 | 4.743 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.928710e-05 | 4.715 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 2.063766e-05 | 4.685 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 2.187527e-05 | 4.660 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 2.099509e-05 | 4.678 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 2.170920e-05 | 4.663 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 2.367346e-05 | 4.626 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 2.453704e-05 | 4.610 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 2.561184e-05 | 4.592 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.619000e-05 | 4.582 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.729190e-05 | 4.564 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 3.031529e-05 | 4.518 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 3.308160e-05 | 4.480 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 3.308160e-05 | 4.480 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 3.077423e-05 | 4.512 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 3.106174e-05 | 4.508 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 3.267060e-05 | 4.486 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 3.575436e-05 | 4.447 | 0 | 0 |
| S Phase | R-HSA-69242 | 3.821132e-05 | 4.418 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 3.849385e-05 | 4.415 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 4.380973e-05 | 4.358 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 4.613974e-05 | 4.336 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 4.952517e-05 | 4.305 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 5.457567e-05 | 4.263 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 5.750825e-05 | 4.240 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 5.793209e-05 | 4.237 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 5.793209e-05 | 4.237 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 6.427321e-05 | 4.192 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 6.201004e-05 | 4.208 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 6.786836e-05 | 4.168 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 7.155918e-05 | 4.145 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 7.269532e-05 | 4.138 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 7.811347e-05 | 4.107 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 8.337426e-05 | 4.079 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 8.355774e-05 | 4.078 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 8.456260e-05 | 4.073 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 8.531681e-05 | 4.069 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 8.805070e-05 | 4.055 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 8.805070e-05 | 4.055 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 8.817458e-05 | 4.055 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 8.907058e-05 | 4.050 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 9.285655e-05 | 4.032 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 9.470378e-05 | 4.024 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.886359e-05 | 4.005 | 0 | 0 |
| Translation | R-HSA-72766 | 1.134567e-04 | 3.945 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.364745e-04 | 3.865 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.364745e-04 | 3.865 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.364745e-04 | 3.865 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.364745e-04 | 3.865 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.360911e-04 | 3.866 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.383884e-04 | 3.859 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.433830e-04 | 3.844 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 1.461486e-04 | 3.835 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.488268e-04 | 3.827 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 1.532928e-04 | 3.814 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.543357e-04 | 3.812 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.749918e-04 | 3.757 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.854584e-04 | 3.732 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.910230e-04 | 3.719 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.713061e-04 | 3.766 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.782561e-04 | 3.749 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.755903e-04 | 3.755 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 1.750795e-04 | 3.757 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.741623e-04 | 3.759 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 1.941421e-04 | 3.712 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.965487e-04 | 3.707 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 2.125018e-04 | 3.673 | 0 | 0 |
| Kinesins | R-HSA-983189 | 2.125018e-04 | 3.673 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 2.164455e-04 | 3.665 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 2.207355e-04 | 3.656 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 2.344701e-04 | 3.630 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 2.474018e-04 | 3.607 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 2.480481e-04 | 3.605 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 2.480481e-04 | 3.605 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.567207e-04 | 3.591 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.835573e-04 | 3.547 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.973949e-04 | 3.527 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 3.039685e-04 | 3.517 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 3.068499e-04 | 3.513 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 3.081991e-04 | 3.511 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 3.299111e-04 | 3.482 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 3.698646e-04 | 3.432 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 3.373793e-04 | 3.472 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 3.382297e-04 | 3.471 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 3.460534e-04 | 3.461 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 3.771729e-04 | 3.423 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 3.598389e-04 | 3.444 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 3.546662e-04 | 3.450 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 3.462441e-04 | 3.461 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 4.261723e-04 | 3.370 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 4.292024e-04 | 3.367 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 4.364711e-04 | 3.360 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 4.388383e-04 | 3.358 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 4.867776e-04 | 3.313 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 4.888432e-04 | 3.311 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 4.946400e-04 | 3.306 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 5.018603e-04 | 3.299 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 5.018603e-04 | 3.299 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 5.309477e-04 | 3.275 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 5.510786e-04 | 3.259 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 5.711332e-04 | 3.243 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 6.057173e-04 | 3.218 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 6.470167e-04 | 3.189 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 7.368337e-04 | 3.133 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 7.368337e-04 | 3.133 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 7.368337e-04 | 3.133 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 7.368337e-04 | 3.133 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 7.371157e-04 | 3.132 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 7.766026e-04 | 3.110 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 7.156782e-04 | 3.145 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 6.993691e-04 | 3.155 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 6.733531e-04 | 3.172 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 6.688787e-04 | 3.175 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 8.027363e-04 | 3.095 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 8.027363e-04 | 3.095 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 8.517574e-04 | 3.070 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 8.517574e-04 | 3.070 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 8.988528e-04 | 3.046 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 9.047212e-04 | 3.043 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 9.383422e-04 | 3.028 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 9.383422e-04 | 3.028 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 9.396970e-04 | 3.027 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 9.436647e-04 | 3.025 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 9.550842e-04 | 3.020 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.707165e-04 | 3.013 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 9.855269e-04 | 3.006 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.008242e-03 | 2.996 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.014346e-03 | 2.994 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.017486e-03 | 2.992 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 1.021941e-03 | 2.991 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 1.028841e-03 | 2.988 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.031064e-03 | 2.987 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 1.061716e-03 | 2.974 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.111369e-03 | 2.954 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.127499e-03 | 2.948 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.169441e-03 | 2.932 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 1.177663e-03 | 2.929 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 1.185957e-03 | 2.926 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 1.202696e-03 | 2.920 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 1.208832e-03 | 2.918 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.233507e-03 | 2.909 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 1.235375e-03 | 2.908 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.239900e-03 | 2.907 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 1.283526e-03 | 2.892 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.343645e-03 | 2.872 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.395126e-03 | 2.855 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.396509e-03 | 2.855 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.396509e-03 | 2.855 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 1.396509e-03 | 2.855 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 1.409615e-03 | 2.851 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 1.468267e-03 | 2.833 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 1.461476e-03 | 2.835 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.579738e-03 | 2.801 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 1.645582e-03 | 2.784 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.721083e-03 | 2.764 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 1.716000e-03 | 2.765 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.771182e-03 | 2.752 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.771977e-03 | 2.752 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 1.970612e-03 | 2.705 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.970612e-03 | 2.705 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.970612e-03 | 2.705 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.974873e-03 | 2.704 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 2.000799e-03 | 2.699 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 2.077088e-03 | 2.683 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 2.077088e-03 | 2.683 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 2.077088e-03 | 2.683 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 2.092756e-03 | 2.679 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 2.092756e-03 | 2.679 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 2.246349e-03 | 2.649 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 2.344737e-03 | 2.630 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 2.359894e-03 | 2.627 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 2.367654e-03 | 2.626 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.367654e-03 | 2.626 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 2.368409e-03 | 2.626 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 2.368409e-03 | 2.626 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 2.371234e-03 | 2.625 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.427526e-03 | 2.615 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 2.525479e-03 | 2.598 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.534051e-03 | 2.596 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 2.608791e-03 | 2.584 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.696988e-03 | 2.569 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 2.896116e-03 | 2.538 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.896116e-03 | 2.538 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 2.985534e-03 | 2.525 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 3.005593e-03 | 2.522 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 3.047641e-03 | 2.516 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 3.055080e-03 | 2.515 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 3.172402e-03 | 2.499 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 3.184622e-03 | 2.497 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.184622e-03 | 2.497 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 3.184622e-03 | 2.497 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.184622e-03 | 2.497 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 3.184622e-03 | 2.497 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 3.195163e-03 | 2.496 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 3.447318e-03 | 2.463 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 3.641733e-03 | 2.439 | 1 | 1 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 3.379216e-03 | 2.471 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 3.928310e-03 | 2.406 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.514113e-03 | 2.454 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 3.596184e-03 | 2.444 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 4.051523e-03 | 2.392 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 3.456484e-03 | 2.461 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 4.160086e-03 | 2.381 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 4.160086e-03 | 2.381 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 3.641733e-03 | 2.439 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 3.631380e-03 | 2.440 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 3.705513e-03 | 2.431 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 3.379216e-03 | 2.471 | 0 | 0 |
| Immune System | R-HSA-168256 | 3.828499e-03 | 2.417 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 4.160182e-03 | 2.381 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 4.160182e-03 | 2.381 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 4.195408e-03 | 2.377 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 4.324966e-03 | 2.364 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 4.505817e-03 | 2.346 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 4.553236e-03 | 2.342 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 4.818575e-03 | 2.317 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 4.882796e-03 | 2.311 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 4.898503e-03 | 2.310 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 4.898503e-03 | 2.310 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 4.925756e-03 | 2.308 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 4.990925e-03 | 2.302 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 5.126024e-03 | 2.290 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 5.126024e-03 | 2.290 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.268389e-03 | 2.278 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 5.340288e-03 | 2.272 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 5.480774e-03 | 2.261 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 5.645832e-03 | 2.248 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 5.645832e-03 | 2.248 | 0 | 0 |
| Depurination | R-HSA-73927 | 5.995351e-03 | 2.222 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 6.089221e-03 | 2.215 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 6.089221e-03 | 2.215 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 6.204803e-03 | 2.207 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 6.241240e-03 | 2.205 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 6.241240e-03 | 2.205 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 6.275597e-03 | 2.202 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 6.308836e-03 | 2.200 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 6.308836e-03 | 2.200 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 6.336479e-03 | 2.198 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 6.411420e-03 | 2.193 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 6.411420e-03 | 2.193 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 6.568399e-03 | 2.183 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 6.800321e-03 | 2.167 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 6.957401e-03 | 2.158 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 6.957401e-03 | 2.158 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 7.174662e-03 | 2.144 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 7.273092e-03 | 2.138 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 7.280216e-03 | 2.138 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 7.314039e-03 | 2.136 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 7.314039e-03 | 2.136 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 7.314039e-03 | 2.136 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 7.377485e-03 | 2.132 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 7.379919e-03 | 2.132 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 7.415978e-03 | 2.130 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 7.487722e-03 | 2.126 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 7.524536e-03 | 2.124 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 7.524536e-03 | 2.124 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 7.524536e-03 | 2.124 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 7.579893e-03 | 2.120 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 7.582893e-03 | 2.120 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 7.779536e-03 | 2.109 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 7.850914e-03 | 2.105 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 7.881525e-03 | 2.103 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 7.881861e-03 | 2.103 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 8.135122e-03 | 2.090 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 8.135122e-03 | 2.090 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 8.135122e-03 | 2.090 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 8.659559e-03 | 2.063 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 8.659559e-03 | 2.063 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 8.659559e-03 | 2.063 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 8.659559e-03 | 2.063 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 8.659559e-03 | 2.063 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 8.667162e-03 | 2.062 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 8.697782e-03 | 2.061 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 8.737598e-03 | 2.059 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 8.917360e-03 | 2.050 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.917360e-03 | 2.050 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 8.917360e-03 | 2.050 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 9.222294e-03 | 2.035 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.406093e-03 | 2.027 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.406093e-03 | 2.027 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 9.406093e-03 | 2.027 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 1.008094e-02 | 1.996 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 9.726422e-03 | 2.012 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.240477e-02 | 1.906 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.240477e-02 | 1.906 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 1.240477e-02 | 1.906 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 1.078567e-02 | 1.967 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.099267e-02 | 1.959 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.069772e-02 | 1.971 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 1.257687e-02 | 1.900 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 1.257687e-02 | 1.900 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 9.861794e-03 | 2.006 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 1.138859e-02 | 1.944 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.132016e-02 | 1.946 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 1.078567e-02 | 1.967 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.175776e-02 | 1.930 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.240477e-02 | 1.906 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.099267e-02 | 1.959 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.099267e-02 | 1.959 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 1.082488e-02 | 1.966 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 1.130226e-02 | 1.947 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 1.257687e-02 | 1.900 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 9.910518e-03 | 2.004 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 1.008094e-02 | 1.996 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.240195e-02 | 1.907 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.240195e-02 | 1.907 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.270984e-02 | 1.896 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 1.280806e-02 | 1.893 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 1.280806e-02 | 1.893 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 1.285045e-02 | 1.891 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.314142e-02 | 1.881 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.314142e-02 | 1.881 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.314142e-02 | 1.881 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 1.349146e-02 | 1.870 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.349146e-02 | 1.870 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.358438e-02 | 1.867 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 1.358438e-02 | 1.867 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 1.358438e-02 | 1.867 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 1.358438e-02 | 1.867 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 1.358438e-02 | 1.867 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 1.419544e-02 | 1.848 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 1.419544e-02 | 1.848 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 1.419544e-02 | 1.848 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 1.440651e-02 | 1.841 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.469104e-02 | 1.833 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.529963e-02 | 1.815 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 1.556256e-02 | 1.808 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.558211e-02 | 1.807 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.558211e-02 | 1.807 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.635957e-02 | 1.786 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.688248e-02 | 1.773 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 1.705612e-02 | 1.768 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.708413e-02 | 1.767 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.708413e-02 | 1.767 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 1.760404e-02 | 1.754 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.760404e-02 | 1.754 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.786426e-02 | 1.748 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 1.786426e-02 | 1.748 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 1.786426e-02 | 1.748 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.786426e-02 | 1.748 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 1.808959e-02 | 1.743 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 1.823009e-02 | 1.739 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 1.833493e-02 | 1.737 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 1.833493e-02 | 1.737 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 1.920922e-02 | 1.716 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.920922e-02 | 1.716 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.920922e-02 | 1.716 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.920922e-02 | 1.716 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 1.923695e-02 | 1.716 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 2.023060e-02 | 1.694 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 2.025227e-02 | 1.694 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 2.027121e-02 | 1.693 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 2.031474e-02 | 1.692 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 2.034264e-02 | 1.692 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 2.050261e-02 | 1.688 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.204153e-02 | 1.657 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 2.231310e-02 | 1.651 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 2.246973e-02 | 1.648 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 2.246973e-02 | 1.648 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 2.246973e-02 | 1.648 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 2.246973e-02 | 1.648 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 2.246973e-02 | 1.648 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 2.246973e-02 | 1.648 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 2.260059e-02 | 1.646 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 2.260059e-02 | 1.646 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 2.265020e-02 | 1.645 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 2.282522e-02 | 1.642 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 2.282522e-02 | 1.642 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 2.306293e-02 | 1.637 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 2.325149e-02 | 1.634 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.346191e-02 | 1.630 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 2.346191e-02 | 1.630 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 3.299075e-02 | 1.482 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 3.299075e-02 | 1.482 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 3.235117e-02 | 1.490 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 3.235117e-02 | 1.490 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 3.462293e-02 | 1.461 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 3.368025e-02 | 1.473 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.485353e-02 | 1.605 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.485353e-02 | 1.605 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 2.865501e-02 | 1.543 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 2.865501e-02 | 1.543 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 2.865501e-02 | 1.543 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 2.865501e-02 | 1.543 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 2.580942e-02 | 1.588 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 2.580942e-02 | 1.588 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 2.790592e-02 | 1.554 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 3.399409e-02 | 1.469 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 2.571418e-02 | 1.590 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 2.466731e-02 | 1.608 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 2.751419e-02 | 1.560 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 2.790592e-02 | 1.554 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 2.874598e-02 | 1.541 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 3.297895e-02 | 1.482 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 3.299075e-02 | 1.482 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 3.235117e-02 | 1.490 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 3.462293e-02 | 1.461 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 3.462293e-02 | 1.461 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 2.580942e-02 | 1.588 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 3.541730e-02 | 1.451 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 2.932777e-02 | 1.533 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 3.316842e-02 | 1.479 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 2.571418e-02 | 1.590 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 2.659589e-02 | 1.575 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 3.079801e-02 | 1.511 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 3.462293e-02 | 1.461 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 2.483387e-02 | 1.605 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 2.813133e-02 | 1.551 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 3.462293e-02 | 1.461 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 2.927553e-02 | 1.533 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 2.874598e-02 | 1.541 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 2.874598e-02 | 1.541 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 2.686916e-02 | 1.571 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.485353e-02 | 1.605 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 2.932777e-02 | 1.533 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 2.444389e-02 | 1.612 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 2.463381e-02 | 1.608 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 3.235117e-02 | 1.490 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 2.932777e-02 | 1.533 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 2.636630e-02 | 1.579 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 3.098122e-02 | 1.509 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.817191e-02 | 1.550 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 2.436713e-02 | 1.613 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 2.790592e-02 | 1.554 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 2.463381e-02 | 1.608 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 2.813133e-02 | 1.551 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 3.316842e-02 | 1.479 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 2.686916e-02 | 1.571 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 3.297895e-02 | 1.482 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 2.603682e-02 | 1.584 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 3.499919e-02 | 1.456 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.826765e-02 | 1.549 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 2.463381e-02 | 1.608 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 2.436713e-02 | 1.613 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 3.555939e-02 | 1.449 | 0 | 0 |
| Defective Base Excision Repair Associated with OGG1 | R-HSA-9656249 | 3.604405e-02 | 1.443 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.604405e-02 | 1.443 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.604405e-02 | 1.443 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 3.657811e-02 | 1.437 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 3.658927e-02 | 1.437 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 3.734319e-02 | 1.428 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 3.782436e-02 | 1.422 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 3.782436e-02 | 1.422 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 3.877554e-02 | 1.411 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 3.913142e-02 | 1.407 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 3.913142e-02 | 1.407 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 3.913142e-02 | 1.407 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 3.972140e-02 | 1.401 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 3.972140e-02 | 1.401 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 4.068353e-02 | 1.391 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 4.133113e-02 | 1.384 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 4.133113e-02 | 1.384 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.196955e-02 | 1.377 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 4.196955e-02 | 1.377 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 4.196955e-02 | 1.377 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 4.196955e-02 | 1.377 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 4.196955e-02 | 1.377 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.196955e-02 | 1.377 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.196955e-02 | 1.377 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 4.196955e-02 | 1.377 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 4.196955e-02 | 1.377 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 4.241448e-02 | 1.372 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 4.241448e-02 | 1.372 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 4.241448e-02 | 1.372 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 4.375037e-02 | 1.359 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 4.375037e-02 | 1.359 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 4.481379e-02 | 1.349 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 4.508090e-02 | 1.346 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 4.508090e-02 | 1.346 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 4.587061e-02 | 1.338 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.640810e-02 | 1.333 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 4.640810e-02 | 1.333 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 4.653055e-02 | 1.332 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 4.704422e-02 | 1.327 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 4.782867e-02 | 1.320 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 4.794981e-02 | 1.319 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 4.889602e-02 | 1.311 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 4.978898e-02 | 1.303 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 4.986878e-02 | 1.302 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 5.015903e-02 | 1.300 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 5.018715e-02 | 1.299 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 5.018715e-02 | 1.299 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 5.018715e-02 | 1.299 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 5.018715e-02 | 1.299 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 5.018715e-02 | 1.299 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 5.039634e-02 | 1.298 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 5.105730e-02 | 1.292 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 5.158123e-02 | 1.288 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 5.197385e-02 | 1.284 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 5.197385e-02 | 1.284 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 5.197385e-02 | 1.284 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 5.197385e-02 | 1.284 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 5.367368e-02 | 1.270 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 5.367368e-02 | 1.270 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 5.367368e-02 | 1.270 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 5.367368e-02 | 1.270 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 5.372092e-02 | 1.270 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 5.375262e-02 | 1.270 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 5.434744e-02 | 1.265 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 5.667904e-02 | 1.247 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 5.758066e-02 | 1.240 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 5.905737e-02 | 1.229 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 5.928272e-02 | 1.227 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 5.928272e-02 | 1.227 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 5.928272e-02 | 1.227 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 5.928272e-02 | 1.227 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 5.928272e-02 | 1.227 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 5.928272e-02 | 1.227 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 5.995689e-02 | 1.222 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 6.011894e-02 | 1.221 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 6.011894e-02 | 1.221 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 6.011894e-02 | 1.221 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 6.011894e-02 | 1.221 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 6.011894e-02 | 1.221 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 6.086058e-02 | 1.216 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 6.139819e-02 | 1.212 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 6.157126e-02 | 1.211 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 6.176240e-02 | 1.209 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 6.264408e-02 | 1.203 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 6.300687e-02 | 1.201 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 6.308982e-02 | 1.200 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 6.356306e-02 | 1.197 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 6.356306e-02 | 1.197 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 6.372489e-02 | 1.196 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 6.583935e-02 | 1.182 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 6.900130e-02 | 1.161 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 6.918313e-02 | 1.160 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 6.918313e-02 | 1.160 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 6.918313e-02 | 1.160 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 6.925461e-02 | 1.160 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.985176e-02 | 1.156 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 6.992537e-02 | 1.155 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 6.992537e-02 | 1.155 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 7.136751e-02 | 1.146 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 7.184720e-02 | 1.144 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 7.248430e-02 | 1.140 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 7.287098e-02 | 1.137 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 7.310113e-02 | 1.136 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.385758e-02 | 1.132 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 7.403682e-02 | 1.131 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 7.403682e-02 | 1.131 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 7.582805e-02 | 1.120 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 7.582805e-02 | 1.120 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 7.582805e-02 | 1.120 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 7.582805e-02 | 1.120 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 7.582805e-02 | 1.120 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.590330e-02 | 1.120 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 7.667050e-02 | 1.115 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 7.667050e-02 | 1.115 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 7.667050e-02 | 1.115 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 7.667050e-02 | 1.115 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 7.733223e-02 | 1.112 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 7.733223e-02 | 1.112 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 7.782739e-02 | 1.109 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.782739e-02 | 1.109 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 7.817988e-02 | 1.107 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 7.818917e-02 | 1.107 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 7.818917e-02 | 1.107 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 7.872610e-02 | 1.104 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 7.872610e-02 | 1.104 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 7.945268e-02 | 1.100 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 7.945268e-02 | 1.100 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 7.945268e-02 | 1.100 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 7.978360e-02 | 1.098 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 8.009298e-02 | 1.096 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 8.009298e-02 | 1.096 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 8.379989e-02 | 1.077 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 8.379989e-02 | 1.077 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 8.379989e-02 | 1.077 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 8.379989e-02 | 1.077 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 8.486679e-02 | 1.071 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 8.505520e-02 | 1.070 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 8.505520e-02 | 1.070 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 8.601724e-02 | 1.065 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 8.697989e-02 | 1.061 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 8.697989e-02 | 1.061 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 8.818129e-02 | 1.055 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 8.952315e-02 | 1.048 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 8.953835e-02 | 1.048 | 0 | 0 |
| Defective OGG1 Substrate Binding | R-HSA-9656255 | 9.396771e-02 | 1.027 | 0 | 0 |
| Defective OGG1 Localization | R-HSA-9657050 | 9.396771e-02 | 1.027 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 9.396771e-02 | 1.027 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 1.791105e-01 | 0.747 | 0 | 0 |
| Defective OGG1 Substrate Processing | R-HSA-9656256 | 1.791105e-01 | 0.747 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.791105e-01 | 0.747 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.791105e-01 | 0.747 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.791105e-01 | 0.747 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.791105e-01 | 0.747 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.791105e-01 | 0.747 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.791105e-01 | 0.747 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 1.791105e-01 | 0.747 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.791105e-01 | 0.747 | 0 | 0 |
| RPIA deficiency: failed conversion of RU5P to R5P | R-HSA-6791461 | 1.791105e-01 | 0.747 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 1.791105e-01 | 0.747 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH3 | R-HSA-5632927 | 1.791105e-01 | 0.747 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 1.791105e-01 | 0.747 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.791105e-01 | 0.747 | 0 | 0 |
| RPIA deficiency: failed conversion of R5P to RU5P | R-HSA-5659996 | 1.791105e-01 | 0.747 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.192701e-01 | 0.923 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.192701e-01 | 0.923 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.192701e-01 | 0.923 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.192701e-01 | 0.923 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 1.192701e-01 | 0.923 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.192701e-01 | 0.923 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 1.525696e-01 | 0.817 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 1.525696e-01 | 0.817 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 9.660887e-02 | 1.015 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 1.170238e-01 | 0.932 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 1.619805e-01 | 0.791 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 1.619805e-01 | 0.791 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 1.209202e-01 | 0.918 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 9.178031e-02 | 1.037 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 1.042920e-01 | 0.982 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 1.175973e-01 | 0.930 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 1.560254e-01 | 0.807 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.004374e-01 | 0.998 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.748457e-01 | 0.757 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.748457e-01 | 0.757 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 1.748457e-01 | 0.757 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 1.748457e-01 | 0.757 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 1.618846e-01 | 0.791 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 1.361108e-01 | 0.866 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 1.152316e-01 | 0.938 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.806560e-02 | 1.008 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 1.779528e-01 | 0.750 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 1.164125e-01 | 0.934 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 1.164125e-01 | 0.934 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 1.164125e-01 | 0.934 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.262292e-01 | 0.899 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 1.364620e-01 | 0.865 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 1.581278e-01 | 0.801 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.695328e-01 | 0.771 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 1.180905e-01 | 0.928 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 1.372088e-01 | 0.863 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 1.070219e-01 | 0.971 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 1.259905e-01 | 0.900 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 1.074865e-01 | 0.969 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.170238e-01 | 0.932 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 1.004374e-01 | 0.998 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 1.070219e-01 | 0.971 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 1.049753e-01 | 0.979 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.029178e-01 | 0.988 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 1.470993e-01 | 0.832 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.525696e-01 | 0.817 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 1.768640e-01 | 0.752 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 9.077741e-02 | 1.042 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.161387e-01 | 0.935 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.627624e-01 | 0.788 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.409105e-01 | 0.851 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.409105e-01 | 0.851 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.409105e-01 | 0.851 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.409105e-01 | 0.851 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 8.975209e-02 | 1.047 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 1.175973e-01 | 0.930 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 1.345463e-01 | 0.871 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.070219e-01 | 0.971 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 1.042920e-01 | 0.982 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 1.175673e-01 | 0.930 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 1.175673e-01 | 0.930 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 9.660887e-02 | 1.015 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 1.192701e-01 | 0.923 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 1.192701e-01 | 0.923 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 9.660887e-02 | 1.015 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.170238e-01 | 0.932 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 1.581278e-01 | 0.801 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 1.046583e-01 | 0.980 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.560254e-01 | 0.807 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.380211e-01 | 0.860 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 1.758261e-01 | 0.755 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.922973e-02 | 1.003 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 1.048052e-01 | 0.980 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 9.178031e-02 | 1.037 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 1.581278e-01 | 0.801 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 1.525696e-01 | 0.817 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 9.660887e-02 | 1.015 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 1.048052e-01 | 0.980 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 9.210142e-02 | 1.036 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.409105e-01 | 0.851 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.791105e-01 | 0.747 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.192701e-01 | 0.923 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 1.192701e-01 | 0.923 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 1.525696e-01 | 0.817 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 1.388800e-01 | 0.857 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.048052e-01 | 0.980 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 1.316594e-01 | 0.881 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 1.748457e-01 | 0.757 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 1.788710e-01 | 0.747 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 1.501995e-01 | 0.823 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 9.724868e-02 | 1.012 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 1.546909e-01 | 0.811 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 1.737270e-01 | 0.760 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.560254e-01 | 0.807 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 1.004374e-01 | 0.998 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.470993e-01 | 0.832 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 1.695328e-01 | 0.771 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 1.175973e-01 | 0.930 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 1.042920e-01 | 0.982 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 1.170238e-01 | 0.932 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 9.523393e-02 | 1.021 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 9.720513e-02 | 1.012 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 1.501995e-01 | 0.823 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 1.175973e-01 | 0.930 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 9.523393e-02 | 1.021 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 1.175973e-01 | 0.930 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.262292e-01 | 0.899 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 1.525696e-01 | 0.817 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.316594e-01 | 0.881 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 1.316594e-01 | 0.881 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 1.737270e-01 | 0.760 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 1.124769e-01 | 0.949 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.372375e-01 | 0.863 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 1.580993e-01 | 0.801 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.316594e-01 | 0.881 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.209202e-01 | 0.918 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 1.042920e-01 | 0.982 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.560254e-01 | 0.807 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.668451e-01 | 0.778 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 1.042920e-01 | 0.982 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.748457e-01 | 0.757 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.491676e-01 | 0.826 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 1.812983e-01 | 0.742 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 1.829039e-01 | 0.738 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.861289e-01 | 0.730 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.861289e-01 | 0.730 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 1.861289e-01 | 0.730 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 1.861289e-01 | 0.730 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 1.861289e-01 | 0.730 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.861289e-01 | 0.730 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 1.864894e-01 | 0.729 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 1.865901e-01 | 0.729 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.865901e-01 | 0.729 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.865901e-01 | 0.729 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 1.867369e-01 | 0.729 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 1.873904e-01 | 0.727 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.873904e-01 | 0.727 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 1.873904e-01 | 0.727 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 1.873904e-01 | 0.727 | 0 | 0 |
| Proton/oligopeptide cotransporters | R-HSA-427975 | 1.873904e-01 | 0.727 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.873904e-01 | 0.727 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.873904e-01 | 0.727 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.873904e-01 | 0.727 | 0 | 0 |
| Diseases of Base Excision Repair | R-HSA-9605308 | 1.873904e-01 | 0.727 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 1.873904e-01 | 0.727 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.914395e-01 | 0.718 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 1.914395e-01 | 0.718 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 1.914395e-01 | 0.718 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.934071e-01 | 0.714 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 1.934071e-01 | 0.714 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 1.936682e-01 | 0.713 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 1.943916e-01 | 0.711 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 1.943916e-01 | 0.711 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 1.943916e-01 | 0.711 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.945900e-01 | 0.711 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 1.959435e-01 | 0.708 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 1.960201e-01 | 0.708 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.979407e-01 | 0.703 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 1.984813e-01 | 0.702 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 2.001314e-01 | 0.699 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 2.029468e-01 | 0.693 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 2.064538e-01 | 0.685 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 2.064538e-01 | 0.685 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 2.086793e-01 | 0.681 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 2.111331e-01 | 0.675 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 2.111331e-01 | 0.675 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 2.117422e-01 | 0.674 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 2.117422e-01 | 0.674 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 2.117422e-01 | 0.674 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 2.124391e-01 | 0.673 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.133112e-01 | 0.671 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 2.137408e-01 | 0.670 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 2.145709e-01 | 0.668 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 2.145709e-01 | 0.668 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.145709e-01 | 0.668 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 2.145709e-01 | 0.668 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 2.145709e-01 | 0.668 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 2.218707e-01 | 0.654 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 2.218707e-01 | 0.654 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 2.218707e-01 | 0.654 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 2.218707e-01 | 0.654 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.231532e-01 | 0.651 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 2.231532e-01 | 0.651 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 2.231532e-01 | 0.651 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 2.231532e-01 | 0.651 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 2.231532e-01 | 0.651 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 2.293541e-01 | 0.639 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 2.293541e-01 | 0.639 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 2.336244e-01 | 0.631 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 2.352910e-01 | 0.628 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 2.352910e-01 | 0.628 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 2.352910e-01 | 0.628 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 2.352910e-01 | 0.628 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.352910e-01 | 0.628 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 2.368082e-01 | 0.626 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 2.368082e-01 | 0.626 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 2.368082e-01 | 0.626 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.368082e-01 | 0.626 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 2.368082e-01 | 0.626 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 2.368082e-01 | 0.626 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 2.376526e-01 | 0.624 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 2.423639e-01 | 0.616 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 2.446528e-01 | 0.611 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.473696e-01 | 0.607 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.473696e-01 | 0.607 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 2.473696e-01 | 0.607 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 2.473696e-01 | 0.607 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 2.537613e-01 | 0.596 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 2.537613e-01 | 0.596 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 2.562567e-01 | 0.591 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.562567e-01 | 0.591 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 2.562567e-01 | 0.591 | 0 | 0 |
| Defective HK1 causes hexokinase deficiency (HK deficiency) | R-HSA-5619056 | 2.562567e-01 | 0.591 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 2.562567e-01 | 0.591 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.562567e-01 | 0.591 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.562567e-01 | 0.591 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.562567e-01 | 0.591 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.562567e-01 | 0.591 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.562567e-01 | 0.591 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.562567e-01 | 0.591 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 2.562567e-01 | 0.591 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.562567e-01 | 0.591 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.562567e-01 | 0.591 | 0 | 0 |
| NTRK3 as a dependence receptor | R-HSA-9603505 | 2.562567e-01 | 0.591 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 2.564602e-01 | 0.591 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 2.564602e-01 | 0.591 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 2.570335e-01 | 0.590 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.593737e-01 | 0.586 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.593737e-01 | 0.586 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.593737e-01 | 0.586 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.593737e-01 | 0.586 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 2.593737e-01 | 0.586 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 2.593737e-01 | 0.586 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 2.593737e-01 | 0.586 | 0 | 0 |
| SLC-mediated transport of oligopeptides | R-HSA-9959399 | 2.593737e-01 | 0.586 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 2.593737e-01 | 0.586 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.593737e-01 | 0.586 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.621081e-01 | 0.582 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 2.629785e-01 | 0.580 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 2.629785e-01 | 0.580 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 2.657321e-01 | 0.576 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 2.657321e-01 | 0.576 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 2.657321e-01 | 0.576 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 2.657321e-01 | 0.576 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.657321e-01 | 0.576 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 2.719520e-01 | 0.566 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 2.719520e-01 | 0.566 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 2.743437e-01 | 0.562 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 2.768613e-01 | 0.558 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 2.779884e-01 | 0.556 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 2.843856e-01 | 0.546 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 2.843856e-01 | 0.546 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 2.844003e-01 | 0.546 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 2.868034e-01 | 0.542 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 2.870906e-01 | 0.542 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 2.894797e-01 | 0.538 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 2.894797e-01 | 0.538 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 2.934028e-01 | 0.533 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 2.956504e-01 | 0.529 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.956504e-01 | 0.529 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 2.956504e-01 | 0.529 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 2.956504e-01 | 0.529 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 2.956504e-01 | 0.529 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 2.970429e-01 | 0.527 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 2.997883e-01 | 0.523 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 2.997883e-01 | 0.523 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 2.997883e-01 | 0.523 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 3.002593e-01 | 0.523 | 0 | 0 |
| Disease | R-HSA-1643685 | 3.006618e-01 | 0.522 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 3.010438e-01 | 0.521 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 3.013718e-01 | 0.521 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 3.036590e-01 | 0.518 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 3.036590e-01 | 0.518 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 3.065300e-01 | 0.514 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 3.161590e-01 | 0.500 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 3.161590e-01 | 0.500 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 3.161590e-01 | 0.500 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 3.161590e-01 | 0.500 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 3.199572e-01 | 0.495 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 3.206860e-01 | 0.494 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 3.206860e-01 | 0.494 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 3.206860e-01 | 0.494 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 3.206860e-01 | 0.494 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 3.206860e-01 | 0.494 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 3.206860e-01 | 0.494 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 3.206860e-01 | 0.494 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 3.217756e-01 | 0.492 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 3.217756e-01 | 0.492 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 3.217756e-01 | 0.492 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 3.217756e-01 | 0.492 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 3.261570e-01 | 0.487 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.261570e-01 | 0.487 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.261570e-01 | 0.487 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.261570e-01 | 0.487 | 0 | 0 |
| Defective AHCY causes HMAHCHD | R-HSA-5578997 | 3.261570e-01 | 0.487 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 3.261570e-01 | 0.487 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.261570e-01 | 0.487 | 0 | 0 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 | R-HSA-5083633 | 3.261570e-01 | 0.487 | 0 | 0 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 | R-HSA-5083629 | 3.261570e-01 | 0.487 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.261570e-01 | 0.487 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 3.261570e-01 | 0.487 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.261570e-01 | 0.487 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 3.305894e-01 | 0.481 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 3.316532e-01 | 0.479 | 0 | 0 |
| Hypusine synthesis from eIF5A-lysine | R-HSA-204626 | 3.316532e-01 | 0.479 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 3.316532e-01 | 0.479 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 3.316532e-01 | 0.479 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 3.316532e-01 | 0.479 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 3.316532e-01 | 0.479 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 3.316532e-01 | 0.479 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.316532e-01 | 0.479 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 3.335369e-01 | 0.477 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.372175e-01 | 0.472 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 3.415410e-01 | 0.467 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 3.418985e-01 | 0.466 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 3.428765e-01 | 0.465 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.428765e-01 | 0.465 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 3.428765e-01 | 0.465 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 3.428765e-01 | 0.465 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 3.434740e-01 | 0.464 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 3.438701e-01 | 0.464 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 3.438701e-01 | 0.464 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 3.551023e-01 | 0.450 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 3.579338e-01 | 0.446 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 3.580804e-01 | 0.446 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 3.607871e-01 | 0.443 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 3.659956e-01 | 0.437 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 3.659956e-01 | 0.437 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 3.659956e-01 | 0.437 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 3.659956e-01 | 0.437 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.671133e-01 | 0.435 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 3.671133e-01 | 0.435 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 3.671133e-01 | 0.435 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 3.671133e-01 | 0.435 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 3.671133e-01 | 0.435 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.671133e-01 | 0.435 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 3.695047e-01 | 0.432 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.695047e-01 | 0.432 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 3.727504e-01 | 0.429 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 3.801151e-01 | 0.420 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 3.801151e-01 | 0.420 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 3.801151e-01 | 0.420 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 3.801151e-01 | 0.420 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 3.880808e-01 | 0.411 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 3.894914e-01 | 0.410 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 3.894914e-01 | 0.410 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 3.894914e-01 | 0.410 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 3.894914e-01 | 0.410 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.894914e-01 | 0.410 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.894914e-01 | 0.410 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.894914e-01 | 0.410 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.894914e-01 | 0.410 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 3.894914e-01 | 0.410 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 3.894914e-01 | 0.410 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 3.894914e-01 | 0.410 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 3.894914e-01 | 0.410 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 3.915110e-01 | 0.407 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 3.933296e-01 | 0.405 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 3.959292e-01 | 0.402 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 3.959292e-01 | 0.402 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 3.959292e-01 | 0.402 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 3.959292e-01 | 0.402 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.993954e-01 | 0.399 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 4.018149e-01 | 0.396 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 4.018149e-01 | 0.396 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 4.018149e-01 | 0.396 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 4.018149e-01 | 0.396 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 4.018149e-01 | 0.396 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 4.018149e-01 | 0.396 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 4.021947e-01 | 0.396 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 4.100589e-01 | 0.387 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 4.100589e-01 | 0.387 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 4.100589e-01 | 0.387 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 4.169269e-01 | 0.380 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 4.186108e-01 | 0.378 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 4.186108e-01 | 0.378 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 4.186108e-01 | 0.378 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 4.220478e-01 | 0.375 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 4.243751e-01 | 0.372 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 4.318683e-01 | 0.365 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 4.318683e-01 | 0.365 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.355875e-01 | 0.361 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 4.355875e-01 | 0.361 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 4.355875e-01 | 0.361 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 4.443275e-01 | 0.352 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 4.468765e-01 | 0.350 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 4.468765e-01 | 0.350 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 4.468765e-01 | 0.350 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.468765e-01 | 0.350 | 0 | 0 |
| Defective FMO3 causes TMAU | R-HSA-5579019 | 4.468765e-01 | 0.350 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 4.468765e-01 | 0.350 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 4.468765e-01 | 0.350 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.468765e-01 | 0.350 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 4.468765e-01 | 0.350 | 0 | 0 |
| Extrinsic Pathway of Fibrin Clot Formation | R-HSA-140834 | 4.468765e-01 | 0.350 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 4.468765e-01 | 0.350 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 4.468765e-01 | 0.350 | 0 | 0 |
| Toxicity of tetanus toxin (tetX) | R-HSA-5250982 | 4.468765e-01 | 0.350 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.477704e-01 | 0.349 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 4.477704e-01 | 0.349 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 4.511065e-01 | 0.346 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 4.534523e-01 | 0.343 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 4.619327e-01 | 0.335 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 4.682991e-01 | 0.329 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 4.682991e-01 | 0.329 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 4.682991e-01 | 0.329 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 4.682991e-01 | 0.329 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 4.682991e-01 | 0.329 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 4.682991e-01 | 0.329 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 4.682991e-01 | 0.329 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 4.682991e-01 | 0.329 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 4.682991e-01 | 0.329 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 4.682991e-01 | 0.329 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 4.730185e-01 | 0.325 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 4.730185e-01 | 0.325 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 4.730185e-01 | 0.325 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 4.751818e-01 | 0.323 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 4.754574e-01 | 0.323 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 4.756765e-01 | 0.323 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 4.846782e-01 | 0.315 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 4.898975e-01 | 0.310 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 4.977246e-01 | 0.303 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 4.977246e-01 | 0.303 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 4.977246e-01 | 0.303 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 4.988707e-01 | 0.302 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 4.988707e-01 | 0.302 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 4.988707e-01 | 0.302 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.988707e-01 | 0.302 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.988707e-01 | 0.302 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 4.988707e-01 | 0.302 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 4.988707e-01 | 0.302 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 4.988707e-01 | 0.302 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.988707e-01 | 0.302 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 4.988707e-01 | 0.302 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 4.988707e-01 | 0.302 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 4.988707e-01 | 0.302 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 4.988707e-01 | 0.302 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 4.988707e-01 | 0.302 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 4.988707e-01 | 0.302 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 4.998510e-01 | 0.301 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 4.998510e-01 | 0.301 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 4.998510e-01 | 0.301 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 4.998510e-01 | 0.301 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 4.998510e-01 | 0.301 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.998510e-01 | 0.301 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 4.998510e-01 | 0.301 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 5.022444e-01 | 0.299 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 5.123262e-01 | 0.290 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 5.163611e-01 | 0.287 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 5.205209e-01 | 0.284 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 5.218313e-01 | 0.282 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 5.218313e-01 | 0.282 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 5.292354e-01 | 0.276 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 5.301721e-01 | 0.276 | 0 | 0 |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA | R-HSA-77348 | 5.301721e-01 | 0.276 | 0 | 0 |
| Beta oxidation of hexanoyl-CoA to butanoyl-CoA | R-HSA-77350 | 5.301721e-01 | 0.276 | 0 | 0 |
| Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA | R-HSA-77310 | 5.301721e-01 | 0.276 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 5.301721e-01 | 0.276 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 5.301721e-01 | 0.276 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 5.301721e-01 | 0.276 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 5.301721e-01 | 0.276 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 5.301721e-01 | 0.276 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 5.303574e-01 | 0.275 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.324881e-01 | 0.274 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 5.365771e-01 | 0.270 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 5.365771e-01 | 0.270 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 5.367017e-01 | 0.270 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 5.420273e-01 | 0.266 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 5.452908e-01 | 0.263 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 5.452908e-01 | 0.263 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 5.452908e-01 | 0.263 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 5.452908e-01 | 0.263 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.459801e-01 | 0.263 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.459801e-01 | 0.263 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.459801e-01 | 0.263 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 5.459801e-01 | 0.263 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.459801e-01 | 0.263 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 5.459801e-01 | 0.263 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 5.459801e-01 | 0.263 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 5.459801e-01 | 0.263 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 5.459801e-01 | 0.263 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 5.459801e-01 | 0.263 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 5.459801e-01 | 0.263 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 5.459801e-01 | 0.263 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 5.459801e-01 | 0.263 | 0 | 0 |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors | R-HSA-389397 | 5.459801e-01 | 0.263 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 5.459801e-01 | 0.263 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 5.459801e-01 | 0.263 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 5.480843e-01 | 0.261 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 5.480843e-01 | 0.261 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 5.506064e-01 | 0.259 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 5.538004e-01 | 0.257 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 5.563585e-01 | 0.255 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 5.563585e-01 | 0.255 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 5.592150e-01 | 0.252 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 5.592150e-01 | 0.252 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 5.654833e-01 | 0.248 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 5.654833e-01 | 0.248 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 5.678666e-01 | 0.246 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 5.680642e-01 | 0.246 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 5.680642e-01 | 0.246 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 5.807218e-01 | 0.236 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 5.825338e-01 | 0.235 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 5.825338e-01 | 0.235 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 5.869522e-01 | 0.231 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 5.869522e-01 | 0.231 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 5.869522e-01 | 0.231 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 5.869522e-01 | 0.231 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 5.869522e-01 | 0.231 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 5.869522e-01 | 0.231 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 5.869522e-01 | 0.231 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 5.886635e-01 | 0.230 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.886635e-01 | 0.230 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.886635e-01 | 0.230 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.886635e-01 | 0.230 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.886635e-01 | 0.230 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 5.886635e-01 | 0.230 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.886635e-01 | 0.230 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.886635e-01 | 0.230 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 5.886635e-01 | 0.230 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 5.886635e-01 | 0.230 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 5.886635e-01 | 0.230 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 5.886635e-01 | 0.230 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.886635e-01 | 0.230 | 0 | 0 |
| Leukotriene receptors | R-HSA-391906 | 5.886635e-01 | 0.230 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 5.886635e-01 | 0.230 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 5.887363e-01 | 0.230 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 5.901206e-01 | 0.229 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 5.901206e-01 | 0.229 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 5.901206e-01 | 0.229 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 5.901206e-01 | 0.229 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 5.901206e-01 | 0.229 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 5.901206e-01 | 0.229 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 5.992172e-01 | 0.222 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 6.086050e-01 | 0.216 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 6.114366e-01 | 0.214 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 6.114366e-01 | 0.214 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 6.114366e-01 | 0.214 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 6.114366e-01 | 0.214 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 6.128360e-01 | 0.213 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 6.133724e-01 | 0.212 | 0 | 0 |
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA | R-HSA-77346 | 6.133724e-01 | 0.212 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 6.133724e-01 | 0.212 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 6.133724e-01 | 0.212 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 6.133724e-01 | 0.212 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 6.133724e-01 | 0.212 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 6.273364e-01 | 0.202 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 6.273364e-01 | 0.202 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 6.273364e-01 | 0.202 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 6.273364e-01 | 0.202 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.273364e-01 | 0.202 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 6.273364e-01 | 0.202 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 6.273364e-01 | 0.202 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 6.273364e-01 | 0.202 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 6.273364e-01 | 0.202 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 6.273364e-01 | 0.202 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.273364e-01 | 0.202 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 6.273364e-01 | 0.202 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 6.273364e-01 | 0.202 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 6.273364e-01 | 0.202 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 6.273364e-01 | 0.202 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 6.319953e-01 | 0.199 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 6.319953e-01 | 0.199 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 6.319953e-01 | 0.199 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 6.319953e-01 | 0.199 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 6.330886e-01 | 0.199 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 6.336432e-01 | 0.198 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 6.384781e-01 | 0.195 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 6.384781e-01 | 0.195 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 6.384781e-01 | 0.195 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 6.384781e-01 | 0.195 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 6.474156e-01 | 0.189 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.474156e-01 | 0.189 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 6.474156e-01 | 0.189 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 6.483073e-01 | 0.188 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 6.490304e-01 | 0.188 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 6.490304e-01 | 0.188 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 6.517860e-01 | 0.186 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 6.517860e-01 | 0.186 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 6.517860e-01 | 0.186 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 6.532763e-01 | 0.185 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 6.612411e-01 | 0.180 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 6.622828e-01 | 0.179 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 6.622828e-01 | 0.179 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 6.622828e-01 | 0.179 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 6.622828e-01 | 0.179 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 6.622828e-01 | 0.179 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 6.622828e-01 | 0.179 | 0 | 0 |
| PKA activation | R-HSA-163615 | 6.622828e-01 | 0.179 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 6.622828e-01 | 0.179 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 6.622828e-01 | 0.179 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.623755e-01 | 0.179 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.623755e-01 | 0.179 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 6.623755e-01 | 0.179 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.623755e-01 | 0.179 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 6.623755e-01 | 0.179 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.623755e-01 | 0.179 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 6.623755e-01 | 0.179 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 6.623755e-01 | 0.179 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 6.623755e-01 | 0.179 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 6.623755e-01 | 0.179 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 6.623755e-01 | 0.179 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 6.623755e-01 | 0.179 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 6.623755e-01 | 0.179 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.623755e-01 | 0.179 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 6.623755e-01 | 0.179 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.623755e-01 | 0.179 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 6.646335e-01 | 0.177 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 6.646335e-01 | 0.177 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 6.680766e-01 | 0.175 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 6.708033e-01 | 0.173 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 6.708033e-01 | 0.173 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.743723e-01 | 0.171 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 6.751899e-01 | 0.171 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 6.833245e-01 | 0.165 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 6.833245e-01 | 0.165 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 6.833245e-01 | 0.165 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 6.848093e-01 | 0.164 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 6.848093e-01 | 0.164 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.848093e-01 | 0.164 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 6.848093e-01 | 0.164 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 6.848093e-01 | 0.164 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 6.848093e-01 | 0.164 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 6.848093e-01 | 0.164 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 6.890467e-01 | 0.162 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.941219e-01 | 0.159 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 6.941219e-01 | 0.159 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 6.941219e-01 | 0.159 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 6.941219e-01 | 0.159 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.941219e-01 | 0.159 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 6.941219e-01 | 0.159 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.941219e-01 | 0.159 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.941219e-01 | 0.159 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 6.941219e-01 | 0.159 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 6.941219e-01 | 0.159 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.941219e-01 | 0.159 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 6.941219e-01 | 0.159 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 6.941219e-01 | 0.159 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 6.941219e-01 | 0.159 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 6.941219e-01 | 0.159 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 6.964269e-01 | 0.157 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 6.981335e-01 | 0.156 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 7.060874e-01 | 0.151 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 7.060874e-01 | 0.151 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 7.060874e-01 | 0.151 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 7.060874e-01 | 0.151 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 7.081170e-01 | 0.150 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 7.114909e-01 | 0.148 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 7.228850e-01 | 0.141 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 7.228850e-01 | 0.141 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 7.228850e-01 | 0.141 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 7.228850e-01 | 0.141 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 7.228850e-01 | 0.141 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 7.228850e-01 | 0.141 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 7.232297e-01 | 0.141 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 7.261527e-01 | 0.139 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 7.261527e-01 | 0.139 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 7.261527e-01 | 0.139 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 7.261527e-01 | 0.139 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 7.272940e-01 | 0.138 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 7.323365e-01 | 0.135 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 7.323365e-01 | 0.135 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 7.430655e-01 | 0.129 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 7.450450e-01 | 0.128 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 7.450450e-01 | 0.128 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 7.453105e-01 | 0.128 | 0 | 0 |
| DAG1 core M3 glycosylations | R-HSA-8932505 | 7.489448e-01 | 0.126 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 7.489448e-01 | 0.126 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 7.489448e-01 | 0.126 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 7.489448e-01 | 0.126 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 7.489448e-01 | 0.126 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.489448e-01 | 0.126 | 0 | 0 |
| Conjugation of benzoate with glycine | R-HSA-177135 | 7.489448e-01 | 0.126 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 7.489448e-01 | 0.126 | 0 | 0 |
| Propionyl-CoA catabolism | R-HSA-71032 | 7.489448e-01 | 0.126 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 7.489448e-01 | 0.126 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 7.489448e-01 | 0.126 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.489448e-01 | 0.126 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.489448e-01 | 0.126 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 7.515556e-01 | 0.124 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 7.544053e-01 | 0.122 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 7.554931e-01 | 0.122 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 7.557419e-01 | 0.122 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 7.628075e-01 | 0.118 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 7.628075e-01 | 0.118 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 7.628075e-01 | 0.118 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 7.628075e-01 | 0.118 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.628075e-01 | 0.118 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 7.628075e-01 | 0.118 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 7.688997e-01 | 0.114 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 7.725554e-01 | 0.112 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.725554e-01 | 0.112 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 7.725554e-01 | 0.112 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.725554e-01 | 0.112 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 7.725554e-01 | 0.112 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 7.725554e-01 | 0.112 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 7.725554e-01 | 0.112 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.725554e-01 | 0.112 | 0 | 0 |
| FMO oxidises nucleophiles | R-HSA-217271 | 7.725554e-01 | 0.112 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 7.725554e-01 | 0.112 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 7.725554e-01 | 0.112 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 7.725554e-01 | 0.112 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 7.735188e-01 | 0.112 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.783188e-01 | 0.109 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 7.794856e-01 | 0.108 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 7.814953e-01 | 0.107 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 7.939468e-01 | 0.100 | 0 | 0 |
| Beta oxidation of palmitoyl-CoA to myristoyl-CoA | R-HSA-77305 | 7.939468e-01 | 0.100 | 0 | 0 |
| Beta oxidation of myristoyl-CoA to lauroyl-CoA | R-HSA-77285 | 7.939468e-01 | 0.100 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 7.939468e-01 | 0.100 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 7.939468e-01 | 0.100 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 7.939468e-01 | 0.100 | 0 | 0 |
| Acetylation | R-HSA-156582 | 7.939468e-01 | 0.100 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.939468e-01 | 0.100 | 0 | 0 |
| Conjugation of salicylate with glycine | R-HSA-177128 | 7.939468e-01 | 0.100 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.939468e-01 | 0.100 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 7.939468e-01 | 0.100 | 0 | 0 |
| Synthesis of GDP-mannose | R-HSA-446205 | 7.939468e-01 | 0.100 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 7.939468e-01 | 0.100 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 7.939468e-01 | 0.100 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 7.939468e-01 | 0.100 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 7.939468e-01 | 0.100 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 7.939468e-01 | 0.100 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 7.939468e-01 | 0.100 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.939468e-01 | 0.100 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 7.951261e-01 | 0.100 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 7.951261e-01 | 0.100 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.951261e-01 | 0.100 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 7.951261e-01 | 0.100 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 7.957889e-01 | 0.099 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 7.957889e-01 | 0.099 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 7.957889e-01 | 0.099 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 7.994680e-01 | 0.097 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 7.995635e-01 | 0.097 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 8.017142e-01 | 0.096 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 8.020672e-01 | 0.096 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 8.033725e-01 | 0.095 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 8.082232e-01 | 0.092 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 8.088016e-01 | 0.092 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 8.097765e-01 | 0.092 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.097765e-01 | 0.092 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 8.097765e-01 | 0.092 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 8.133275e-01 | 0.090 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 8.133275e-01 | 0.090 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 8.133275e-01 | 0.090 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 8.133275e-01 | 0.090 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 8.189934e-01 | 0.087 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 8.234847e-01 | 0.084 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.234847e-01 | 0.084 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 8.278919e-01 | 0.082 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.308863e-01 | 0.080 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 8.308863e-01 | 0.080 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.308863e-01 | 0.080 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 8.308863e-01 | 0.080 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.308863e-01 | 0.080 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 8.308863e-01 | 0.080 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.308863e-01 | 0.080 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.308863e-01 | 0.080 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 8.311778e-01 | 0.080 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 8.311778e-01 | 0.080 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 8.329798e-01 | 0.079 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 8.362983e-01 | 0.078 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.362983e-01 | 0.078 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 8.362983e-01 | 0.078 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 8.417429e-01 | 0.075 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 8.417429e-01 | 0.075 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 8.420780e-01 | 0.075 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.467945e-01 | 0.072 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.467945e-01 | 0.072 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 8.467945e-01 | 0.072 | 0 | 0 |
| Transport and metabolism of PAPS | R-HSA-174362 | 8.467945e-01 | 0.072 | 0 | 0 |
| Beta oxidation of butanoyl-CoA to acetyl-CoA | R-HSA-77352 | 8.467945e-01 | 0.072 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 8.467945e-01 | 0.072 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 8.467945e-01 | 0.072 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 8.467945e-01 | 0.072 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 8.467945e-01 | 0.072 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 8.482642e-01 | 0.071 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 8.482642e-01 | 0.071 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 8.482642e-01 | 0.071 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 8.482642e-01 | 0.071 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 8.510172e-01 | 0.070 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.611635e-01 | 0.065 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.612070e-01 | 0.065 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 8.612070e-01 | 0.065 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 8.612070e-01 | 0.065 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 8.612070e-01 | 0.065 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 8.612070e-01 | 0.065 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 8.612070e-01 | 0.065 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 8.612070e-01 | 0.065 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 8.671462e-01 | 0.062 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 8.672019e-01 | 0.062 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.698361e-01 | 0.061 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 8.700654e-01 | 0.060 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 8.742645e-01 | 0.058 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 8.742645e-01 | 0.058 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of unsaturated fatty acids | R-HSA-77288 | 8.742645e-01 | 0.058 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 8.742645e-01 | 0.058 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.742645e-01 | 0.058 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 8.742645e-01 | 0.058 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.742645e-01 | 0.058 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 8.742645e-01 | 0.058 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.742645e-01 | 0.058 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.795305e-01 | 0.056 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.795305e-01 | 0.056 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 8.795305e-01 | 0.056 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 8.795305e-01 | 0.056 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.806380e-01 | 0.055 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 8.822400e-01 | 0.054 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 8.860943e-01 | 0.053 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.860943e-01 | 0.053 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 8.860943e-01 | 0.053 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.860943e-01 | 0.053 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.860943e-01 | 0.053 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 8.863383e-01 | 0.052 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 8.885537e-01 | 0.051 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 8.885537e-01 | 0.051 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 8.885537e-01 | 0.051 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 8.895137e-01 | 0.051 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.960753e-01 | 0.048 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 8.968117e-01 | 0.047 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 8.969462e-01 | 0.047 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 8.969462e-01 | 0.047 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 8.969462e-01 | 0.047 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.022917e-01 | 0.045 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.047468e-01 | 0.043 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 9.054215e-01 | 0.043 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.058847e-01 | 0.043 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 9.065212e-01 | 0.043 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 9.065212e-01 | 0.043 | 0 | 0 |
| Conjugation of carboxylic acids | R-HSA-159424 | 9.065212e-01 | 0.043 | 0 | 0 |
| Amino Acid conjugation | R-HSA-156587 | 9.065212e-01 | 0.043 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.065212e-01 | 0.043 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 9.065212e-01 | 0.043 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 9.065212e-01 | 0.043 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.113141e-01 | 0.040 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.119924e-01 | 0.040 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.119924e-01 | 0.040 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.135859e-01 | 0.039 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.137453e-01 | 0.039 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.137453e-01 | 0.039 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.149585e-01 | 0.039 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 9.153177e-01 | 0.038 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.153177e-01 | 0.038 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 9.153177e-01 | 0.038 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.153177e-01 | 0.038 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.153177e-01 | 0.038 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.153177e-01 | 0.038 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.225814e-01 | 0.035 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.231493e-01 | 0.035 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.232869e-01 | 0.035 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 9.232869e-01 | 0.035 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.232869e-01 | 0.035 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.232869e-01 | 0.035 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 9.232869e-01 | 0.035 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.232869e-01 | 0.035 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.242783e-01 | 0.034 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.242783e-01 | 0.034 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 9.245604e-01 | 0.034 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.248419e-01 | 0.034 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.249587e-01 | 0.034 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 9.305065e-01 | 0.031 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.305065e-01 | 0.031 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 9.305065e-01 | 0.031 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.307447e-01 | 0.031 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 9.361068e-01 | 0.029 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.361068e-01 | 0.029 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.361068e-01 | 0.029 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.361068e-01 | 0.029 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 9.361068e-01 | 0.029 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.370471e-01 | 0.028 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.370471e-01 | 0.028 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.370471e-01 | 0.028 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.370471e-01 | 0.028 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.391220e-01 | 0.027 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.391220e-01 | 0.027 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.392227e-01 | 0.027 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.410734e-01 | 0.026 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.429724e-01 | 0.026 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.429724e-01 | 0.026 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 9.429724e-01 | 0.026 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.429724e-01 | 0.026 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 9.456716e-01 | 0.024 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.463602e-01 | 0.024 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.473470e-01 | 0.023 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.483404e-01 | 0.023 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.483404e-01 | 0.023 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.484644e-01 | 0.023 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.532033e-01 | 0.021 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.532033e-01 | 0.021 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.532033e-01 | 0.021 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.532033e-01 | 0.021 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 9.538623e-01 | 0.021 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.538623e-01 | 0.021 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.538623e-01 | 0.021 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.544508e-01 | 0.020 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.544508e-01 | 0.020 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.575011e-01 | 0.019 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.575318e-01 | 0.019 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.576088e-01 | 0.019 | 0 | 0 |
| Linoleic acid (LA) metabolism | R-HSA-2046105 | 9.576088e-01 | 0.019 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.576088e-01 | 0.019 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.576088e-01 | 0.019 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.576088e-01 | 0.019 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 9.605167e-01 | 0.017 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.606500e-01 | 0.017 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.615997e-01 | 0.017 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.615997e-01 | 0.017 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.616503e-01 | 0.017 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.618233e-01 | 0.017 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.634436e-01 | 0.016 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.639706e-01 | 0.016 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.652152e-01 | 0.015 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.661640e-01 | 0.015 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids | R-HSA-77286 | 9.668394e-01 | 0.015 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.668394e-01 | 0.015 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.684783e-01 | 0.014 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 9.684904e-01 | 0.014 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.684904e-01 | 0.014 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 9.684904e-01 | 0.014 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.694876e-01 | 0.013 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.694876e-01 | 0.013 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.713512e-01 | 0.013 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.714574e-01 | 0.013 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.714574e-01 | 0.013 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.753878e-01 | 0.011 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.762644e-01 | 0.010 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.765801e-01 | 0.010 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.778775e-01 | 0.010 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.781808e-01 | 0.010 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.783527e-01 | 0.010 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.787857e-01 | 0.009 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.799996e-01 | 0.009 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.807838e-01 | 0.008 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.807838e-01 | 0.008 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.807838e-01 | 0.008 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.807838e-01 | 0.008 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.825938e-01 | 0.008 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.825938e-01 | 0.008 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.825938e-01 | 0.008 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.825938e-01 | 0.008 | 0 | 0 |
| Phosphate bond hydrolysis by NUDT proteins | R-HSA-2393930 | 9.825938e-01 | 0.008 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.842334e-01 | 0.007 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.842334e-01 | 0.007 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.842334e-01 | 0.007 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.842334e-01 | 0.007 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.851715e-01 | 0.006 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.882827e-01 | 0.005 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.882827e-01 | 0.005 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.889768e-01 | 0.005 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.898664e-01 | 0.004 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.903867e-01 | 0.004 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.903867e-01 | 0.004 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.906474e-01 | 0.004 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.907029e-01 | 0.004 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.907434e-01 | 0.004 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.912926e-01 | 0.004 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.916243e-01 | 0.004 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.922171e-01 | 0.003 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.923485e-01 | 0.003 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.934239e-01 | 0.003 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.935297e-01 | 0.003 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.935297e-01 | 0.003 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.936534e-01 | 0.003 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.937014e-01 | 0.003 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.941395e-01 | 0.003 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.941395e-01 | 0.003 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.941395e-01 | 0.003 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.944745e-01 | 0.002 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.951923e-01 | 0.002 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.953600e-01 | 0.002 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.954709e-01 | 0.002 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.955720e-01 | 0.002 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.955720e-01 | 0.002 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.956455e-01 | 0.002 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.956455e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.960560e-01 | 0.002 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.964278e-01 | 0.002 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.964332e-01 | 0.002 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.964332e-01 | 0.002 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.964332e-01 | 0.002 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.967335e-01 | 0.001 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.967646e-01 | 0.001 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.967951e-01 | 0.001 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.970089e-01 | 0.001 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.970375e-01 | 0.001 | 0 | 0 |
| Cytosolic sulfonation of small molecules | R-HSA-156584 | 9.970697e-01 | 0.001 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.970697e-01 | 0.001 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.974344e-01 | 0.001 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.974929e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.980779e-01 | 0.001 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.980779e-01 | 0.001 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.981368e-01 | 0.001 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.982413e-01 | 0.001 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.982800e-01 | 0.001 | 0 | 0 |
| Sialic acid metabolism | R-HSA-4085001 | 9.986734e-01 | 0.001 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.987986e-01 | 0.001 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.989119e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.989119e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.991076e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.991918e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.993997e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.994474e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.995542e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.995962e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.995962e-01 | 0.000 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.997001e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.997084e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.997084e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.997563e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.997748e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.997780e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.998174e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.998503e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.998521e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.998888e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.998970e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999253e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999259e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999539e-01 | 0.000 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.999588e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999627e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999644e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999672e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999716e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999723e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999725e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999794e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999850e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999875e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999927e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999938e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999949e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999962e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999965e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999984e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999987e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 9.999987e-01 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 9.999990e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999992e-01 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 9.999992e-01 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 9.999993e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 9.999995e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999995e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999996e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999998e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.999998e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999998e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999999e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999999e-01 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 1.000000e+00 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
