NEK6

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities

T Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

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substrate_uniprot site source substrate_genes site_seq
A5A3E0 S1065 Sugiyama POTEF A26C1B ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 S939 Sugiyama POTEF A26C1B VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NMY6 S161 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B QEINRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAE
A6NMY6 S164 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGS
A6NMY6 T163 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
O00115 S57 Sugiyama DNASE2 DNASE2A DNL2 ALRGSGEAAQRGLQYKyLDEssGGWRDGRALINsPEGAVGR
O00141 S377 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP SGK1 SGK LINWDDLINKKItPPFNPNVsGPNDLRHFDPEFTEEPVPNs
O00141 S422 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP SGK1 SGK PDsVLVTAsVKEAAEAFLGFsYAPPTDSFL___________
O00170 S53 Sugiyama AIP XAP2 KATFHYRtLHsDDEGtVLDDsRARGKPMELIIGKKFKLPVW
O00273 T300 Sugiyama DFFA DFF1 DFF45 H13 KKTETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDL
O00443 S108 Sugiyama PIK3C2A LDIDVEKLTQAELEKLLLDDsFETKKTPVLPVTPILSPSFS
O00443 S59 Sugiyama PIK3C2A LAKLQKDRQVTDNQRGFELsssTRKKAQVyNKQDyDLMVFP
O00443 S60 Sugiyama PIK3C2A AKLQKDRQVTDNQRGFELsssTRKKAQVyNKQDyDLMVFPE
O14737 S51 Sugiyama PDCD5 TFAR19 EAKHREAEMRNsILAQVLDQsARARLsNLALVKPEKTKAVE
O14818 T147 Sugiyama PSMA7 HSPC FGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKS
O14818 T152 Sugiyama PSMA7 HSPC LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL
O14818 Y145 Sugiyama PSMA7 HSPC RPFGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGA
O15067 S225 Sugiyama PFAS KIAA0361 KRFQELQRNPstVEAFDLAQsNsEHSRHWFFKGQLHVDGQK
O15067 S227 Sugiyama PFAS KIAA0361 FQELQRNPstVEAFDLAQsNsEHSRHWFFKGQLHVDGQKLV
O15212 S53 Sugiyama PFDN6 HKE2 PFD6 LEAQLtENNIVKEELALLDGsNVVFKLLGPVLVKQELGEAR
O15355 S363 Sugiyama PPM1G PPM1C VANAGDsRCVVsEAGKALDMsyDHKPEDEVELARIKNAGGK
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O15397 S29 Sugiyama IPO8 RANBP8 ALKGTIDPKLRIAAENELNQsYKIINFAPSLLRIIVSDHVE
O43175 S14 Sugiyama PHGDH PGDH3 _______MAFANLRKVLIsDsLDPCCRKILQDGGLQVVEKQ
O43390 T134 Sugiyama HNRNPR HNRPR KVQESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O43390 T141 Sugiyama HNRNPR HNRPR GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP
O43390 Y136 Sugiyama HNRNPR HNRPR QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O43423 S100 Sugiyama ANP32CP PP32R1 AEKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCE
O43615 S94 Sugiyama TIMM44 MIMT44 TIM44 NKEMKESIKKFRDEARRLEEsDVLQEARRKyKtIESETVRT
O43615 T198 Sugiyama TIMM44 MIMT44 TIM44 ALsQGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEFAGDKF
O43707 T612 Sugiyama ACTN4 KEAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPK
O43707 T613 Sugiyama ACTN4 EAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPKR
O43852 S69 Sugiyama CALU HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt
O60220 S94 Sugiyama TIMM8A DDP DDP1 TIM8A SQFILNRLEQTQKSKPVFSEsLsD_________________
O60231 S56 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 RCTSAEEFVQRLRDtDTLDLsGPARDFALRLWNKVPRKAVV
O60271 S815 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 IASVPGARETDYPAGEDLsEsGQVDKASLCGSMTSNSSAET
O60271 T191 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 MEHLERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPA
O60271 T418 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 DEGADLLGMGREVENLILENtQLLEtKNALNIVKNDLIAKV
O60271 T423 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 LLGMGREVENLILENtQLLEtKNALNIVKNDLIAKVDELTC
O60343 S304 Sugiyama TBC1D4 AS160 KIAA0603 ASQPALTSSRVCFPERILEDsGFDEQQEFRsRCssVTGVQR
O60506 T131 Sugiyama SYNCRIP HNRPQ NSAP1 KVADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O60506 T138 Sugiyama SYNCRIP HNRPQ NSAP1 GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP
O60506 Y133 Sugiyama SYNCRIP HNRPQ NSAP1 ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O60566 T608 Sugiyama BUB1B BUBR1 MAD3L SSK1 SEDAIITGFRNVtICPNPEDtCDFARAARFVStPFHEIMSL
O60664 S254 Sugiyama PLIN3 M6PRBP1 TIP47 SyFVRLGsLSERLRQHAyEHsLGKLRATKQRAQEALLQLSQ
O60701 S381 Sugiyama UGDH GAHLHIYDPKVPREQIVVDLsHPGVSEDDQVsRLVTISKDP
O60749 S354 Sugiyama SNX2 TRG9 RKELSANTAAFAKSAAMLGNsEDHTALSRALsQLAEVEEKI
O60763 S880 Sugiyama USO1 VDP LKNEIKALSEERTAIKEQLDssNsTIAILQTEKDKLELEIT
O60763 S883 Sugiyama USO1 VDP EIKALSEERTAIKEQLDssNsTIAILQTEKDKLELEITDSK
O60841 S196 Sugiyama EIF5B IF2 KIAA0741 ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN
O75116 S930 Sugiyama ROCK2 KIAA0619 SLAAQLEITLTKADSEQLARsIAEEQysDLEKEKIMKELEI
O75116 T567 Sugiyama ROCK2 KIAA0619 NQNSQISTEKVNQLQRQLDEtNALLRtESDTAARLRKTQAE
O75116 T573 Sugiyama ROCK2 KIAA0619 STEKVNQLQRQLDEtNALLRtESDTAARLRKTQAESSKQIQ
O75179 S1159 Sugiyama ANKRD17 GTAR KIAA0697 GADIEAQSERTKDTPLSLACsGGRQEVVELLLARGANKEHR
O75179 S156 Sugiyama ANKRD17 GTAR KIAA0697 ILDQDDLENPMLETASKLLLsGtADGADLRTVDPETQARLE
O75179 T158 Sugiyama ANKRD17 GTAR KIAA0697 DQDDLENPMLETASKLLLsGtADGADLRTVDPETQARLEAL
O75347 S60 Sugiyama TBCA MRAEDGENyDIKKQAEILQEsRMMIPDCQRRLEAAyLDLQR
O75436 T102 Sugiyama VPS26A VPS26 KSNTHEFVNLVKELALPGELtQSRSYDFEFMQVEKPYESYI
O75534 S74 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR SQYNGNLQDLKVGDDVEFEVsSDRRTGKPIAVKLVKIKQEI
O75534 S766 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR AAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDNsMGFG
O75663 S94 Sugiyama TIPRL RCVNNyQGMLKVACAEEWQEsRtEGEHSKEVIKPyDWTyTT
O75663 T96 Sugiyama TIPRL VNNyQGMLKVACAEEWQEsRtEGEHSKEVIKPyDWTyTTDY
O75821 S189 Sugiyama EIF3G EIF3S4 CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK
O75821 T27 Sugiyama EIF3G EIF3S4 DsKPsWADQVEEEGEDDKCVtsELLKGIPLAtGDtsPEPEL
O76094 S524 Sugiyama SRP72 KHLPSSDSMSLKVDVEALENsAGAtyIRKKGGKVTGDsQPK
O95235 S240 EPSD|PSP KIF20A MKLP2 RAB6KIFL EEMKKLSLLNGGLQEEELstsLKRsVYIESRIGtstsFDsG
O95235 S244 SIGNOR|EPSD|PSP KIF20A MKLP2 RAB6KIFL KLSLLNGGLQEEELstsLKRsVYIESRIGtstsFDsGIAGL
O95235 S683 EPSD|PSP KIF20A MKLP2 RAB6KIFL VAHQQsGsELALRRsQRLAAsAstQQLQEVKAKLQQCKAEL
O95235 S754 EPSD|PSP KIF20A MKLP2 RAB6KIFL LEEGQKNIRLLRTELQKLGEsLQsAERACCHSTGAGKLRQA
O95235 S883 EPSD|PSP KIF20A MKLP2 RAB6KIFL StDCsPyARILRSRRsPLLKsGPFGKKY_____________
O95292 S160 Sugiyama VAPB UNQ484/PRO983 IIstTAsKtEtPIVSKsLsssLDDtEVKKVMEECKRLQGEV
O95479 S106 Sugiyama H6PD GDH CPKDMAPSHCAEHKDQFLQLsQYRQLKTAEDYQALNKDIEA
O95626 S104 Sugiyama ANP32D PP32R2 AEKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCE
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95716 T78 Sugiyama RAB3D GOV RAB16 DFKVKTVYRHDKRIKLQIWDtAGQERYRtITTAYYRGAMGF
O95757 S587 Sugiyama HSPA4L APG1 HSPH3 OSP94 RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM
O95757 S599 Sugiyama HSPA4L APG1 HSPH3 OSP94 sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND
O95816 S208 Sugiyama BAG2 IKLLEHSKGAGSKTLQQNAEsRFN_________________
O95816 S31 Sugiyama BAG2 NEGRFCRsssMADRsSRLLEsLDQLELRVEALREAATAVEQ
O95831 T188 Sugiyama AIFM1 AIF PDCD8 LPYMRPPLSKELWFSDDPNVtKtLRFKQWNGKERSIYFQPP
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00558 S175 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02545 S295 Sugiyama LMNA LMN1 RQsAERNsNLVGAAHEELQQsRIRIDsLsAQLsQLQKQLAA
P02786 S151 Sugiyama TFRC LsEKLDstDFTGtIKLLNENsyVPREAGsQKDENLALyVEN
P02786 T138 Sugiyama TFRC AARRLyWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAG
P02786 T143 Sugiyama TFRC yWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAGsQKDE
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S354 Sugiyama ALDOA ALDA ANsLACQGKytPsGQAGAAAsEsLFVsNHAy__________
P04075 S356 Sugiyama ALDOA ALDA sLACQGKytPsGQAGAAAsEsLFVsNHAy____________
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S360 Sugiyama ALDOA ALDA QGKytPsGQAGAAAsEsLFVsNHAy________________
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T123 Sugiyama ALDOA ALDA GVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGA
P04075 T124 Sugiyama ALDOA ALDA VVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGAD
P04075 T49 Sugiyama ALDOA ALDA GILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDR
P04083 S173 Sugiyama ANXA1 ANX1 LPC1 NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG
P04083 S189 Sugiyama ANXA1 ANX1 LPC1 tsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsDARALyEA
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04083 T169 Sugiyama ANXA1 ANX1 LPC1 IRDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRs
P04150 S125 Sugiyama NR3C1 GRL PQQGQISLSSGETDLKLLEEsIANLNRstsVPENPKSSAST
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S151 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV
P04406 S210 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 S321 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05198 S219 Sugiyama EIF2S1 EIF2A CYGYEGIDAVKEALRAGLNCsTENMPIKINLIAPPRYVMTT
P05362 T448 Sugiyama ICAM1 ELKCLKDGtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTR
P05362 T454 Sugiyama ICAM1 DGtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTRKVTVNV
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05783 S323 Sugiyama KRT18 CYK18 PIG46 VQsLEIDLDsMRNLKAsLENsLREVEARYALQMEQLNGILL
P05783 S399 Sugiyama KRT18 CYK18 PIG46 TYRRLLEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVV
P05783 S401 Sugiyama KRT18 CYK18 PIG46 RRLLEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVVsE
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S410 Sugiyama KRT8 CYK8 TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P05787 T413 Sugiyama KRT8 CYK8 KLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGLtsP
P06733 S14 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA
P06733 S27 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733 S310 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VsIEDPFDQDDWGAWQKFtAsAGIQVVGDDLTVtNPKRIAK
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T323 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AWQKFtAsAGIQVVGDDLTVtNPKRIAKAVNEKsCNCLLLK
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 T55 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06748 S137 Sugiyama NPM1 NPM VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 S88 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNG
P07355 S161 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D QEINRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAE
P07355 S164 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGs
P07355 T163 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07737 S30 Sugiyama PFN1 NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV
P07737 S85 Sugiyama PFN1 tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK
P07737 T65 Sugiyama PFN1 PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs
P07814 S1473 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 CEDWIKKtTARDQDLEPGAPsMGAKSLCIPFKPLCELQPGA
P07814 S1511 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PGAKCVCGKNPAKyytLFGRsy___________________
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 S882 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 AQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAK
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S164 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGT
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S169 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA TVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILH
P07900 S399 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK
P07900 S406 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA RGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKKCLELFtE
P07900 S468 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA GIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQ
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S52 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07942 S448 Sugiyama LAMB1 CKLNVEGEHCDVCKEGFyDLssEDPFGCKSCACNPLGTIPG
P08134 T60 Sugiyama RHOC ARH9 ARHC ENYIADIEVDGKQVELALWDtAGQEDYDRLRPLSYPDTDVI
P08195 S296 Sugiyama SLC3A2 MDU1 DLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNYRGEN
P08195 S402 Sugiyama SLC3A2 MDU1 SSDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQY
P08195 S403 Sugiyama SLC3A2 MDU1 SDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYL
P08195 S408 Sugiyama SLC3A2 MDU1 ILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGN
P08195 S598 Sugiyama SLC3A2 MDU1 LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08195 T599 Sugiyama SLC3A2 MDU1 QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH
P08195 Y404 Sugiyama SLC3A2 MDU1 DLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLN
P08238 S159 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGT
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S164 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB VVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILH
P08238 S391 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK
P08238 S398 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKKCLELFsE
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09417 S163 Sugiyama QDPR DHPR SDR33C1 GTPGMIGYGMAKGAVHQLCQsLAGKNSGMPPGAAAIAVLPV
P09622 S502 Sugiyama DLD GCSL LAD PHE3 RVCHAHPTLSEAFREANLAAsFGKSINF_____________
P09960 S486 Sugiyama LTA4H LTA4 TNACIALSQRWITAKEDDLNsFNAtDLKDLsSHQLNEFLAQ
P09960 S496 Sugiyama LTA4H LTA4 WITAKEDDLNsFNAtDLKDLsSHQLNEFLAQtLQRAPLPLG
P09960 S581 Sugiyama LTA4H LTA4 EQGRMKFTRPLFKDLAAFDKsHDQAVRTYQEHKASMHPVTA
P09960 T507 Sugiyama LTA4H LTA4 FNAtDLKDLsSHQLNEFLAQtLQRAPLPLGHIKRMQEVYNF
P09972 S356 Sugiyama ALDOC ALDC GLAAQGKYEGSGEDGGAAAQsLyIANHAY____________
P09972 S36 Sugiyama ALDOC ALDC LsDIALRIVAPGKGILAADEsVGsMAKRLsQIGVENtEENR
P09972 T123 Sugiyama ALDOC ALDC IVVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGA
P0CG38 S1065 Sugiyama POTEI ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1028 Sugiyama POTEJ ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG41 S140 Sugiyama CTAGE8 AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH
P0DMV8 T66 SIGNOR|EPSD|PSP HSPA1A HSP72 HSPA1 HSX70 DTERLIGDAAKNQVALNPQNtVFDAKRLIGRKFGDPVVQsD
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7 T41 Sugiyama TUBA3C TUBA2 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P0DPH7 T56 Sugiyama TUBA3C TUBA2 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
P10599 T100 Sugiyama TXN TRDX TRX TRX1 FKKGQKVGEFSGANKEKLEAtINELV_______________
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P10809 S67 Sugiyama HSPD1 HSP60 LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK
P10809 T428 Sugiyama HSPD1 HSP60 GtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGCALLRCI
P10809 T61 Sugiyama HSPD1 HSP60 LQGVDLLADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVA
P11047 T943 Sugiyama LAMC1 LAMB2 FYNLQSGQGCERCDCHALGstNGQCDIRTGQCECQPGITGQ
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T47 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11586 S129 Sugiyama MTHFD1 MTHFC MTHFD INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP
P11586 S872 Sugiyama MTHFD1 MTHFC MTHFD YTKQGFGNLPICMAKtHLsLsHNPEQKGVPTGFILPIRDIR
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P11717 S1378 Sugiyama IGF2R MPRI QYACPPFDLTECSFKDGAGNsFDLsSLSRYSDNWEAITGTG
P11717 S1382 Sugiyama IGF2R MPRI PPFDLTECSFKDGAGNsFDLsSLSRYSDNWEAITGTGDPEH
P12004 S172 Sugiyama PCNA sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12270 S1185 Sugiyama TPR KLSDKVVASVKEGVQGPLNVsLsEEGKSQEQILEILRFIRR
P12277 S129 Sugiyama CKB CKBB DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG
P12277 S337 Sugiyama CKB CKBB LQKRGtGGVDtAAVGGVFDVsNADRLGFSEVELVQMVVDGV
P13489 S178 Sugiyama RNH1 PRI RNH SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S584 Sugiyama EEF2 EF2 DHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyM
P13639 S587 Sugiyama EEF2 EF2 CIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKAR
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 Y579 Sugiyama EEF2 EF2 KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667 S135 Sugiyama PDIA4 ERP70 ERP72 IPVAKIDAtsAsVLAsRFDVsGyPtIKILKKGQAVDyEGsR
P13667 S154 Sugiyama PDIA4 ERP70 ERP72 VsGyPtIKILKKGQAVDyEGsRtQEEIVAKVREVSQPDWTP
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13667 S468 Sugiyama PDIA4 ERP70 ERP72 ytFAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAM
P13667 S470 Sugiyama PDIA4 ERP70 ERP72 FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP
P13667 S482 Sugiyama PDIA4 ERP70 ERP72 VKDLGLsEsGEDVNAAILDEsGKKFAMEPEEFDsDtLREFV
P13667 T156 Sugiyama PDIA4 ERP70 ERP72 GyPtIKILKKGQAVDyEGsRtQEEIVAKVREVSQPDWTPPP
P13674 T140 Sugiyama P4HA1 P4HA YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13674 Y141 Sugiyama P4HA1 P4HA FPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSF
P13798 S185 Sugiyama APEH D3F15S2 D3S48E DNF15S2 VAEKKRPKAEsFFQTKALDVsAsDDEIARLKKPDQAIKGDQ
P13798 S303 Sugiyama APEH D3F15S2 D3S48E DNF15S2 YYVDLIGGKCELLSDDsLAVssPRLSPDQCRIVYLQYPSLI
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P14314 S478 Sugiyama PRKCSH G19P1 DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S77 Sugiyama PKM OIP3 PK2 PK3 PKM2 sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S447 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 PKyLNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRK
P14625 S514 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK
P14625 S64 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14625 S650 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 KIEKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtG
P14625 S655 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 VVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtGKDIst
P14625 Y652 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 EKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtGKD
P14649 S87 Sugiyama MYL6B MLC1SA EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK
P15153 S158 Sugiyama RAC2 TYPQGLALAKEIDSVKyLECsALtQRGLKtVFDEAIRAVLC
P15311 S535 Sugiyama EZR VIL2 EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN
P15374 S126 Sugiyama UCHL3 NNKDKMHFESGSTLKKFLEEsVsMsPEERARyLENyDAIRV
P16455 S22 Sugiyama MGMT DKDCEMKRTTLDsPLGKLELsGCEQGLHEIKLLGKGTSAAD
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17066 T49 Sugiyama HSPA6 HSP70B' EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P17174 S106 Sugiyama GOT1 RLALGDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNG
P17174 T110 Sugiyama GOT1 GDDsPALKEKRVGGVQsLGGtGALRIGADFLARWYNGTNNK
P17987 S35 Sugiyama TCP1 CCT1 CCTA EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18074 T425 PSP ERCC2 XPD XPDC TLVSTYAKGFTIIIEPFDDRtPTIANPILHFSCMDASLAIK
P18206 S579 Sugiyama VCL AARGEGEsPQARALAsQLQDsLKDLKARMQEAMTQEVsDVF
P18615 S135 Sugiyama NELFE RD RDBP sADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEG
P18621 T79 Sugiyama RPL17 PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P18754 S85 Sugiyama RCC1 CHC1 IPEDVVQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsV
P19338 S328 Sugiyama NCL NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P19338 S591 Sugiyama NCL SKTLFVKGLsEDttEEtLKEsFDGsVRARIVTDRETGssKG
P19338 S595 Sugiyama NCL FVKGLsEDttEEtLKEsFDGsVRARIVTDRETGssKGFGFV
P20073 S216 Sugiyama ANXA7 ANX7 SNX OK/SW-cl.95 KAMKGFGtDEQAIVDVVANRsNDQRQKIKAAFKTSYGKDLI
P20336 T78 Sugiyama RAB3A DFKVKTIYRNDKRIKLQIWDtAGQERYRtITTAYYRGAMGF
P20337 T78 Sugiyama RAB3B DFKVKTVYRHEKRVKLQIWDtAGQERYRtITTAYYRGAMGF
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20618 S162 Sugiyama PSMB1 PSC5 DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG
P20674 T105 Sugiyama COX5A EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY
P21333 S1029 Sugiyama FLNA FLN FLN1 VGPSGAAVPCKVEPGLGADNsVVRFLPREEGPYEVEVTYDG
P22061 S133 Sugiyama PCMT1 KELVDDsVNNVRKDDPTLLssGRVQLVVGDGRMGYAEEAPY
P22102 S105 Sugiyama GART PGFT PRGS NLRsAGVQCFGPTAEAAQLEssKRFAKEFMDRHGIPTAQWK
P22102 S106 Sugiyama GART PGFT PRGS LRsAGVQCFGPTAEAAQLEssKRFAKEFMDRHGIPTAQWKA
P22626 S212 Sugiyama HNRNPA2B1 HNRPA2B1 EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD
P22626 S324 Sugiyama HNRNPA2B1 HNRPA2B1 GNYNQQPSNYGPMKsGNFGGsRNMGGPyGGGNyGPGGsGGs
P22692 S255 Sugiyama IGFBP4 IBP4 VKLPGGLEPKGELDCHQLADsFRE_________________
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23381 T364 Sugiyama WARS1 IFI53 WARS WRS QGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRDtI
P23443 S403 GPS6|SIGNOR|EPSD|PSP RPS6KB1 STK14A DSKFtRQtPVDsPDDstLsEsANQVFLGFtYVAPSVLESVK
P23443 S53 GPS6|SIGNOR|EPSD|PSP RPS6KB1 STK14A DQPEDAGSEDELEEGGQLNEsMDHGGVGPYELGMEHCEKFE
P23443 T412 GPS6|EPSD|PSP RPS6KB1 STK14A VDsPDDstLsEsANQVFLGFtYVAPSVLESVKEKFsFEPKI
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23526 T185 Sugiyama AHCY SAHH yKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGIKR
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23588 S122 Sugiyama EIF4B NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P25398 Y127 Sugiyama RPS12 sCVVVKDYGKESQAKDVIEEyFKCKK_______________
P25786 T11 Sugiyama PSMA1 HC2 NU PROS30 PSC2 __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26232 S667 Sugiyama CTNNA2 CAPR YDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEEKAKIAEQV
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26639 S522 Sugiyama TARS1 TARS PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP
P26639 T700 Sugiyama TARS1 TARS EKISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAE
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27348 S145 Sugiyama YWHAQ YFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHP
P27348 S156 Sugiyama YWHAQ DDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLGLALNFSV
P27348 S37 Sugiyama YWHAQ ERyDDMAtCMKAVtEQGAELsNEERNLLsVAyKNVVGGRRS
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27348 T229 Sugiyama YWHAQ DsyKDstLIMQLLRDNLTLWtsDsAGEECDAAEGAEN____
P27348 Y149 Sugiyama YWHAQ LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG
P27695 S129 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 QELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDE
P27695 S135 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 SHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDEEHDQEG
P27695 T97 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 KKKGLDWVKEEAPDILCLQEtKCSENKLPAELQELPGLSHQ
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 S53 Sugiyama CALR CRTC WtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDAR
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P28482 T351 Sugiyama MAPK1 ERK2 PRKM1 PRKM2 FDMELDDLPKEKLKELIFEEtARFQPGYRS___________
P28838 S194 Sugiyama LAP3 LAPEP PEPS SAKLyGsGDQEAWQKGVLFAsGQNLARQLMETPANEMTPtR
P29144 S1039 Sugiyama TPP2 EEFTEALRDLKIQWMTKLDSsDIyNELKEtyPNyLPLyVAR
P29144 S93 Sugiyama TPP2 SGDVNTATEVEPKDGEIVGLsGRVLKIPASWTNPSGKYHIG
P29401 S190 Sugiyama TKT ASIYKLDNLVAILDINRLGQsDPAPLQHQMDIyQKRCEAFG
P29401 S439 Sugiyama TKT VSIGEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVE
P29401 S443 Sugiyama TKT EDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAAN
P29401 T442 Sugiyama TKT GEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAA
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 S60 Sugiyama EEF1D EF1D ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P29692 S64 Sugiyama EEF1D EF1D sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI
P30040 T43 Sugiyama ERP29 C12orf8 ERP28 LLSAPHGGSGLHTKGALPLDtVtFyKVIPKSKFVLVKFDtQ
P30040 T45 Sugiyama ERP29 C12orf8 ERP28 SAPHGGSGLHTKGALPLDtVtFyKVIPKSKFVLVKFDtQyP
P30050 S138 Sugiyama RPL12 HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG
P30740 S281 Sugiyama SERPINB1 ELANH2 MNEI PI2 PENLDFIEVNVSLPRFKLEEsYTLNSDLARLGVQDLFNssK
P30876 S882 Sugiyama POLR2B GDDVIIGKTVtLPENEDELEstNRRYTKRDCSTFLRTSETG
P31150 S213 Sugiyama GDI1 GDIL OPHN2 RABGDIA XAP4 RTDDyLDQPCLETVNRIKLYsEsLARYGKsPYLyPLyGLGE
P31327 S205 Sugiyama CPS1 FEGQPVDFVDPNKQNLIAEVstKDVKVYGKGNPTKVVAVDC
P31327 S808 Sugiyama CPS1 IGSSMKsVGEVMAIGRTFEEsFQKALRMCHPsIEGFTPRLP
P31327 S898 Sugiyama CPS1 LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31327 T326 Sugiyama CPS1 AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP
P31327 T900 Sugiyama CPS1 KMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKC
P31327 T903 Sugiyama CPS1 DILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKCLGL
P31327 T924 Sugiyama CPS1 LKRAKEIGFSDKQISKCLGLtEAQTRELRLKKNIHPWVKQI
P31939 S370 Sugiyama ATIC PURH OK/SW-cl.86 ALTILSKKKNGNyCVLQMDQsYKPDENEVRTLFGLHLsQKR
P31943 S269 Sugiyama HNRNPH1 HNRPH HNRPH1 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH
P31946 S147 Sugiyama YWHAB YFRyLsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHP
P31946 S158 Sugiyama YWHAB DNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31946 T228 Sugiyama YWHAB LNEEsyKDstLIMQLLRDNLtLWtSENQGDEGDAGEGEN__
P31946 Y151 Sugiyama YWHAB LsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLG
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948 S460 Sugiyama STIP1 AMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRHD
P31949 T33 Sugiyama S100A11 MLN70 S100C CIESLIAVFQKYAGKDGyNytLsKtEFLsFMNTELAAFTKN
P32929 S61 Sugiyama CTH ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA
P32929 S63 Sugiyama CTH LSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGAKY
P33176 S443 Sugiyama KIF5B KNS KNS1 EEIAKLYKQLDDKDEEINQQsQLVEKLKTQMLDQEELLAST
P34896 S17 Sugiyama SHMT1 ____MTMPVNGAHKDADLWSsHDKMLAQPLKDSDVEVyNII
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931 T49 Sugiyama HSPA1L EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV
P34932 T365 Sugiyama HSPA4 APG2 HSPH2 TRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAILsP
P35221 S668 Sugiyama CTNNA1 FDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEQKAKIAEQV
P35237 S306 Sugiyama SERPINB6 PI6 PTI LRNLGMTDAFELGKADFSGMsQTDLSLSKVVHKSFVEVNEE
P35579 S1154 Sugiyama MYH9 KRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKK
P35579 S1714 Sugiyama MYH9 RAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQL
P35579 T1146 Sugiyama MYH9 sRNKAEKQKRDLGEELEALKtELEDtLDstAAQQELRSKRE
P35579 T1151 Sugiyama MYH9 EKQKRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNI
P35579 T1155 Sugiyama MYH9 RDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKKT
P35579 T1313 Sugiyama MYH9 DSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLstKLKQ
P35613 S279 Sugiyama BSG UNQ6505/PRO21383 TDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQy
P35613 S368 SIGNOR BSG UNQ6505/PRO21383 RRKPEDVLDDDDAGsAPLKssGQHQNDKGKNVRQRNSS___
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36871 S134 Sugiyama PGM1 LtAsHNPGGPNGDFGIKFNIsNGGPAPEAITDKIFQISKTI
P36871 S483 Sugiyama PGM1 DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR
P37802 S185 Sugiyama TAGLN2 KIAA0120 CDABP0035 NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38646 S200 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 NyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNVLRVI
P38646 S212 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL
P38646 S550 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYAE
P38646 S554 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 AKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYAEEDRR
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39687 S104 Sugiyama ANP32A C15orf1 LANP MAPM PHAP1 AEKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCE
P40763 S727 GPS6|SIGNOR|EPSD|PSP STAT3 APRF KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS
P40763 Y705 SIGNOR|PSP STAT3 APRF KyCRPEsQEHPEADPGsAAPyLKTKFICVtPttCsNtIDLP
P40855 S147 Sugiyama PEX19 HK33 PXF OK/SW-cl.22 SCLKETLSGLAKNATDLQNssMsEEELTKAMEGLGMDEGDG
P40925 S153 Sugiyama MDH1 MDHA ANtNCLtAsKSAPSIPKENFsCLtRLDHNRAKAQIALKLGV
P41252 T1068 Sugiyama IARS1 IARS PsDKVLIQEKTQLKGSELEItLTRGSSLPGPACAYVNLNIC
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P43034 S161 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA DFERtLKGHtDsVQDIsFDHsGKLLASCSADMTIKLWDFQG
P43243 T239 Sugiyama MATR3 KIAA0723 yEDDRLRDGERCRDDsFFGEtsHNyHKFDsEyERMGRGPGP
P43490 S180 Sugiyama NAMPT PBEF PBEF1 TVATNSREQKKILAKyLLEtsGNLDGLEyKLHDFGyRGVSS
P45974 S783 Sugiyama USP5 ISOT IDDLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQL
P46776 Y108 Sugiyama RPL27A VNAAKNKtGAAPIIDVVRsGyyKVLGKGKLPKQPVIVKAKF
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46782 S75 Sugiyama RPS5 RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P46937 S388 Sugiyama YAP1 YAP65 PGMsQELRTMttNssDPFLNsGtyHsRDEstDsGLsMssys
P46937 S405 Sugiyama YAP1 YAP65 FLNsGtyHsRDEstDsGLsMssysVPRtPDDFLNsVDEMDT
P46940 S482 Sugiyama IQGAP1 KIAA0051 LINRALESGDVNTVWKQLsssVtGLTNIEEENCQRYLDELM
P47712 S729 Sugiyama PLA2G4A CPLA2 PLA2G4 KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P48426 S115 Sugiyama PIP4K2A PI5P4KA PIP5K2 PIP5K2A PMVFRNLRERFGIDDQDFQNsLTRSAPLPNDSQARSGARFH
P48444 S253 Sugiyama ARCN1 COPD KEVDNFVDKLKsEGEtIMSssMGKRTSEATKMHAPPINMES
P48643 S51 Sugiyama CCT5 CCTE KIAA0098 LEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtVT
P48643 T269 Sugiyama CCT5 CCTE KIAA0098 AILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMI
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48739 S165 Sugiyama PITPNB DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P48741 T49 Sugiyama HSPA7 HSP70B EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P49327 S2039 Sugiyama FASN FAS FSSVSCGRGNAGQsNyGFANsAMERICEKRRHEGLPGLAVQ
P49327 S2465 Sugiyama FASN FAS LLRAKtGGAyGEDLGADyNLsQVCDGKVsVHVIEGDHRTLL
P49327 T1999 Sugiyama FASN FAS LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF
P49327 T2215 Sugiyama FASN FAS DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49368 S212 Sugiyama CCT3 CCTG TRIC5 EIDIKKYARVEKIPGGIIEDsCVLRGVMINKDVTHPRMRRY
P49368 S244 Sugiyama CCT3 CCTG TRIC5 VTHPRMRRYIKNPRIVLLDssLEyKKGEsQtDIEITREEDF
P49368 S458 Sugiyama CCT3 CCTG TRIC5 RAVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtW
P49588 T164 Sugiyama AARS1 AARS AGLEADLECKQIWQNLGLDDtKILPGNMKDNFWEMGDtGPC
P49588 T181 Sugiyama AARS1 AARS LDDtKILPGNMKDNFWEMGDtGPCGPCsEIHyDRIGGRDAA
P49589 S305 Sugiyama CARS1 CARS KLVPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKA
P49589 S307 Sugiyama CARS1 CARS VPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKASK
P49792 S1613 Sugiyama RANBP2 NUP358 KAPKSGFEGMFTKKEGQWDCsVCLVRNEASATKCIACQNPG
P50395 S213 Sugiyama GDI2 RABGDIB RtDDyLDQPCyEtINRIKLYsEsLARYGKsPYLyPLyGLGE
P50395 S396 Sugiyama GDI2 RABGDIB IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD
P50395 T205 Sugiyama GDI2 RABGDIB TGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsPYL
P50395 T413 Sugiyama GDI2 RABGDIB GtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFEE
P50395 Y203 Sugiyama GDI2 RABGDIB DFTGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsP
P50542 S167 Sugiyama PEX5 PXR1 EVTDPLSVSPARWAEEyLEQsEEKLWLGEPEGTATDRWYDE
P50570 S357 Sugiyama DNM2 DYN2 GVDFEKRIEGSGDQVDTLELsGGARINRIFHERFPFELVKM
P50613 S161 GPS6|EPSD|PSP CDK7 CAK CAK1 CDKN7 MO15 STK1 NNLLLDENGVLKLADFGLAKsFGsPNRAytHQVVtRWYRAP
P50897 T261 Sugiyama PPT1 CLN1 PPT SEWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLV
P50991 T69 Sugiyama CCT4 CCTD SRB RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR
P50995 S490 Sugiyama ANXA11 ANX11 RSEYKRMYGKsLyHDISGDtsGDyRKILLKICGGND_____
P51532 S1382 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE
P51946 S322 Sugiyama CCNH YVsKKSKHEEEEWtDDDLVEsL___________________
P52272 S633 Sugiyama HNRNPM HNRPM NAGR1 GGGGAsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKAC
P52272 S637 Sugiyama HNRNPM HNRPM NAGR1 AsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKACQIFV
P52429 T204 Sugiyama DGKE DAGK5 NLIIPPSYLTSINQMRKDKKtDyEVLASKLGKQWTPLIILA
P52429 Y206 Sugiyama DGKE DAGK5 IIPPSYLTSINQMRKDKKtDyEVLASKLGKQWTPLIILANS
P52597 S107 Sugiyama HNRNPF HNRPF KSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTKEEI
P52732 S1033 GPS6|SIGNOR|EPSD|PSP KIF11 EG5 KNSL1 TRIP5 QHKKSHGKDKENRGINTLERsKVEETtEHLVTKSRLPLRAQ
P52789 S889 Sugiyama HK2 PHFAKVMHETVKDLAPKCDVsFLQsEDGSGKGAALITAVAC
P52789 S893 Sugiyama HK2 KVMHETVKDLAPKCDVsFLQsEDGSGKGAALITAVACRIRE
P52888 S29 Sugiyama THOP1 GDMADAAsPCSVVNDLRWDLsAQQIEERTRELIEQTKRVyD
P52907 S219 Sugiyama CAPZA1 YEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAENEy
P52948 S608 SIGNOR NUP98 ADAR2 NGAFMPKKsIKKLVLKNLNNsNLFsPVNRDsENLAsPsEyP
P52948 S839 SIGNOR NUP98 ADAR2 AEVtLDGVWPTDKTSRCLIKsPDRLADINyEGRLEAVSRKQ
P53396 S457 Sugiyama ACLY FLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMPQD
P53621 S389 Sugiyama COPA SYNPAENAVLLCTRAsNLENstyDLytIPKDADsQNPDAPE
P53621 T821 Sugiyama COPA IMPLDTNWPLLTVSKGFFEGtIAsKGKGGALAADIDIDTVG
P53675 S1016 Sugiyama CLTCL1 CLH22 CLTCL CLTD MTADLPNELIELLEKIVLDNsVFSEHRNLQNLLILTAIKAD
P54105 S193 Sugiyama CLNS1A CLCI ICLN GLSHLTAEGQATLERLEGMLsQsVssQYNMAGVRtEDsIRD
P54252 S260 Sugiyama ATXN3 ATX3 MJD MJD1 SCA3 IDMEDEEADLRRAIQLsMQGssRNIsQDMtQtsGTNLTSEE
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T48 Sugiyama HSPA2 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI
P55036 T264 Sugiyama PSMD4 MCB1 AEAGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEE
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55072 S765 Sugiyama VCP HEL-220 HEL-S-70 RsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGAGPsQ
P55072 T761 Sugiyama VCP HEL-220 HEL-S-70 RFARRsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGA
P55795 S269 Sugiyama HNRNPH2 FTP3 HNRPH2 YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH
P57721 S82 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK
P58546 T108 Sugiyama MTPN LSKGADKTVKGPDGLTAFEAtDNQAIKALLQ__________
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T90 Sugiyama TPI1 TPI VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI
P60228 S442 Sugiyama EIF3E EIF3S6 INT6 IEKKLNQNSRSEAPNWAtQDsGFy_________________
P60228 Y445 Sugiyama EIF3E EIF3S6 INT6 KLNQNSRSEAPNWAtQDsGFy____________________
P60660 S30 Sugiyama MYL6 AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK
P60660 T22 Sugiyama MYL6 CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S239 Sugiyama ACTB VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709 S300 Sugiyama ACTB NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S365 Sugiyama ACTB ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T202 Sugiyama ACTB GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709 T203 Sugiyama ACTB RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T297 Sugiyama ACTB TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709 T303 Sugiyama ACTB MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P60709 T304 Sugiyama ACTB KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y294 Sugiyama ACTB IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ
P60709 Y306 Sugiyama ACTB DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60763 S158 Sugiyama RAC3 TYPQGLAMAREIGSVKyLECsALtQRGLKtVFDEAIRAVLC
P60842 S300 Sugiyama EIF4A1 DDX2A EIF4A NTRRKVDWLTEKMHARDFTVsAMHGDMDQKERDVIMREFRs
P60981 S88 Sugiyama DSTN ACTDP DSN FKHFVGMLPEKDCRyALyDAsFETKESRKEELMFFLWAPEL
P61006 T64 Sugiyama RAB8A MEL RAB8 DFKIRTIELDGKRIKLQIWDtAGQERFRtITTAYYRGAMGI
P61018 T64 Sugiyama RAB4B RAB4 PP1596 EFGSRVVNVGGKTVKLQIWDtAGQERFRSVTRSYYRGAAGA
P61026 T65 Sugiyama RAB10 DFKIKTVELQGKKIKLQIWDtAGQERFHtIttsYYRGAMGI
P61081 S175 Sugiyama UBE2M UBC12 NNRRLFEQNVQRSMRGGyIGstyFERCLK____________
P61106 T67 Sugiyama RAB14 EFGTRIIEVSGQKIKLQIWDtAGQERFRAVTRSYYRGAAGA
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 S263 Sugiyama RPS3A FTE1 MFTL GDEtGAKVERADGyEPPVQEsV___________________
P61254 S12 Sugiyama RPL26 _________MKFNPFVtsDRsKNRKRHFNAPsHIRRKIMss
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61313 S97 Sugiyama RPL15 EC45 TCBAP0781 KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN
P61586 S160 Sugiyama RHOA ARH12 ARHA RHO12 KPEEGRDMANRIGAFGyMECsAKTKDGVREVFEMAtRAALQ
P61586 T60 Sugiyama RHOA ARH12 ARHA RHO12 ENyVADIEVDGKQVELALWDtAGQEDyDRLRPLSYPDTDVI
P61978 S36 Sugiyama HNRNPK HNRPK NGEFGKRPAEDMEEEQAFKRsRNtDEMVELRILLQSKNAGA
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61978 S77 Sugiyama HNRNPK HNRPK VIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIETI
P61978 T39 Sugiyama HNRNPK HNRPK FGKRPAEDMEEEQAFKRsRNtDEMVELRILLQSKNAGAVIG
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981 T231 Sugiyama YWHAG LNEDsyKDstLIMQLLRDNLtLWtsDQQDDDGGEGNN____
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62258 T229 Sugiyama YWHAE LsEEsyKDstLIMQLLRDNLtLWtsDMQGDGEEQNKEALQD
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62273 S9 Sugiyama RPS29 ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T28 Sugiyama RPS11 RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK
P62495 S239 Sugiyama ETF1 ERF1 RF1 SUP45L1 VNVAGLVLAGSADFKTELSQsDMFDQRLQSKVLKLVDISYG
P62736 S241 Sugiyama ACTA2 ACTSA ACTVS GIG46 VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62745 T60 Sugiyama RHOB ARH6 ARHB ENYVADIEVDGKQVELALWDtAGQEDYDRLRPLSYPDTDVI
P62820 T67 Sugiyama RAB1A RAB1 DFKIRTIELDGKTIKLQIWDtAGQERFRtItsSYYRGAHGI
P62826 S150 Sugiyama RAN ARA24 OK/SW-cl.81 KVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARKLIG
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62873 S207 Sugiyama GNB1 VMSLSLAPDTRLFVSGACDAsAKLWDVREGMCRQTFTGHES
P62879 S207 Sugiyama GNB2 VMSLSLAPDGRTFVSGACDAsIKLWDVRDSMCRQTFIGHES
P62979 S134 Sugiyama RPS27A UBA80 UBCEP1 IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P63000 S158 Sugiyama RAC1 TC25 MIG5 TYPQGLAMAKEIGAVKyLECsALtQRGLKtVFDEAIRAVLC
P63104 S145 Sugiyama YWHAZ YYRyLAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHP
P63104 S156 Sugiyama YWHAZ DDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63104 T226 Sugiyama YWHAZ LsEEsyKDstLIMQLLRDNLtLWtsDtQGDEAEAGEGGEN_
P63104 T30 Sugiyama YWHAZ AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN
P63104 Y149 Sugiyama YWHAZ LAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLG
P63146 S148 Sugiyama UBE2B RAD6B UBCH1 QLYQENKREYEKRVsAIVEQsWNDS________________
P63167 T26 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S239 Sugiyama ACTG1 ACTG VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261 S300 Sugiyama ACTG1 ACTG NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S365 Sugiyama ACTG1 ACTG ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T202 Sugiyama ACTG1 ACTG GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261 T203 Sugiyama ACTG1 ACTG RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T297 Sugiyama ACTG1 ACTG TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261 T303 Sugiyama ACTG1 ACTG MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P63261 T304 Sugiyama ACTG1 ACTG KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y294 Sugiyama ACTG1 ACTG IHETTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQ
P63261 Y306 Sugiyama ACTG1 ACTG DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S240 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P68032 S241 Sugiyama ACTC1 ACTC VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S241 Sugiyama ACTA1 ACTA VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 T41 Sugiyama TUBA1B WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P68363 T56 Sugiyama TUBA1B MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363 Y432 Sugiyama TUBA1B GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
P78417 S23 Sugiyama GSTO1 GSTTLP28 GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK
P78527 S3363 Sugiyama PRKDC HYRC HYRC1 SEPACLAEIEEDKARRILELsGsssEDsEKVIAGLyQRAFQ
P78527 T2645 Sugiyama PRKDC HYRC HYRC1 LSARWPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstD
P78527 T2647 Sugiyama PRKDC HYRC HYRC1 ARWPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstDPL
P78527 T2649 Sugiyama PRKDC HYRC HYRC1 WPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstDPLVD
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P99999 S48 Sugiyama CYCS CYC KTGPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEY
Q00403 S99 Sugiyama GTF2B TF2B TFIIB DLsTMIGKGTGAAsFDEFGNsKYQNRRTMSSSDRAMMNAFK
Q00610 S1016 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 MTADLPNELIELLEKIVLDNsVFSEHRNLQNLLILTAIKAD
Q00610 S1222 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 GDRCyDEKMyDAAKLLyNNVsNFGRLAstLVHLGEyQAAVD
Q00610 S886 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG
Q00653 S739 Sugiyama NFKB2 LYT10 GPEKDtRssFRGHtPLDLTCstKVKTLLLNAAQNTMEPPLT
Q00839 T582 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 CLGKFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRK
Q01082 S1388 Sugiyama SPTBN1 SPTB2 TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy
Q01105 S161 Sugiyama SET FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q04637 S1134 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI RPAtstLNRFsALQQAVPtEsTDNRRVVQRssLsRERGEKA
Q04637 T1132 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI AARPAtstLNRFsALQQAVPtEsTDNRRVVQRssLsRERGE
Q04695 S277 Sugiyama KRT17 RDQYEKMAEKNRKDAEDWFFsKTEELNREVATNsELVQSGK
Q04760 T35 Sugiyama GLO1 AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM
Q04837 S79 Sugiyama SSBP1 SSBP LATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPGLRDVAy
Q04864 S272 Sugiyama REL AITEPVTVKMQLRRPSDQEVsEsMDFRYLPDEKDTYGNKAK
Q04864 S274 Sugiyama REL TEPVTVKMQLRRPSDQEVsEsMDFRYLPDEKDTYGNKAKKQ
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q04917 T231 Sugiyama YWHAH YWHA1 LNEDsyKDstLIMQLLRDNLtLWTSDQQDEEAGEGN_____
Q05586 S890 EPSD|PSP GRIN1 NMDAR1 AEPDPKKKATFRAITSTLAssFKRRRssKDTSTGGGRGALQ
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06265 S287 Sugiyama EXOSC9 PMSCL1 KALENDQKVRKEGGKFGFAEsIANQRITAFKMEKAPIDtsD
Q06323 S55 Sugiyama PSME1 IFI5111 KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE
Q06830 S152 Sugiyama PRDX1 PAGA PAGB TDPX2 IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV
Q06830 S30 Sugiyama PRDX1 PAGA PAGB TDPX2 HPAPNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTF
Q06830 S32 Sugiyama PRDX1 PAGA PAGB TDPX2 APNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTFVC
Q06830 T156 Sugiyama PRDX1 PAGA PAGB TDPX2 KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG
Q06830 T18 Sugiyama PRDX1 PAGA PAGB TDPX2 ___MSSGNAKIGHPAPNFKAtAVMPDGQFKDIsLsDyKGKY
Q07021 S213 Sugiyama C1QBP GC1QBP HABP1 SF2P32 VGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDSLDW
Q08211 S130 Sugiyama DHX9 DDX9 LKP NDH2 GGPLPPHLALKAENNsEVGAsGyGVPGPTWDRGANLKDYYS
Q08345 S788 EPSD|PSP DDR1 CAK EDDR1 NEP NTRK4 PTK3A RTK6 TRKE ATRNCLVGENFTIKIADFGMsRNLyAGDyyRVQGRAVLPIR
Q08378 S1093 Sugiyama GOLGA3 SQELEESREKVLELEDELQEsRGFRKKIKRLEESNKKLALE
Q08378 S501 Sugiyama GOLGA3 ERAMTDLQNMLEAKNAsLAssNNDLQVAEEQyQRLMAKVED
Q08999 S659 EPSD|PSP RBL2 RB2 sPLtPRRVtEVRADTGGLGRsItsPTtLyDRYssPPAStTR
Q08AD1 S476 Sugiyama CAMSAP2 CAMSAP1L1 KIAA1078 NRGITRsIsNEGLtLNNsHVsKHIRKNLSFKPINGEEEAEs
Q08AD1 T469 Sugiyama CAMSAP2 CAMSAP1L1 KIAA1078 SVQRstPNRGITRsIsNEGLtLNNsHVsKHIRKNLSFKPIN
Q13042 T585 Sugiyama CDC16 ANAPC6 FREFEVEKQTAEEtGLtPLEtsRKTPDSRPSLEETFEIEMN
Q13136 S846 Sugiyama PPFIA1 LIP1 ALGQAGVSETDNssQDALGLsKLGGQAEKNRKLQKKHELLE
Q13136 T199 Sugiyama PPFIA1 LIP1 RERLRVALERCSLLEEELGAtHKELMILKEQNNQKKTLTDG
Q13148 S292 Sugiyama TARDBP TDP43 RsGRFGGNPGGFGNQGGFGNsRGGGAGLGNNQGsNMGGGMN
Q13200 S361 SIGNOR|PSP PSMD2 TRAP2 EPKVPDDIyKtHLENNRFGGsGsQVDSARMNLASSFVNGFV
Q13283 S250 Sugiyama G3BP1 G3BP sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI
Q13283 T255 Sugiyama G3BP1 G3BP PADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPHVV
Q13283 Y363 Sugiyama G3BP1 G3BP FIGNLPHEVDKSELKDFFQsyGNVVELRINsGGKLPNFGFV
Q13332 S180 Sugiyama PTPRS GNPDPEITWFKDFLPVDPSAsNGRIKQLRSETFESTPIRGA
Q13347 S217 Sugiyama EIF3I EIF3S2 TRIP1 sRDMtMFVtASKDNTAKLFDsttLEHQKTFRTERPVNSAAL
Q13439 S993 Sugiyama GOLGA4 KLLDQEAKLKKELENTALELsQKEKQFNAKMLEMAQANSAG
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13561 S391 Sugiyama DCTN2 DCTN50 LTQVQTTMRENLATVEGNFAsIDERMKKLGK__________
Q13561 T315 Sugiyama DCTN2 DCTN50 KHKASVEDADTQSKVHQLyEtIQRWsPIASTLPELVQRLVT
Q13617 S230 Sugiyama CUL2 PFLTETGEYYKQEASNLLQEsNCSQYMEKVLGRLKDEEIRC
Q13765 S132 Sugiyama NACA HSD48 YKSPAsDtyIVFGEAKIEDLsQQAQLAAAEKFKVQGEAVsN
Q13765 S186 Sugiyama NACA HSD48 sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI
Q13765 S191 Sugiyama NACA HSD48 VDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDIVNAIM
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q14141 S408 Sugiyama SEPTIN6 KIAA0128 SEP2 SEPT6 sLDDEVNAFKQRKTAAELLQsQGsQAGGsQtLKRDKEKKNN
Q14151 S194 Sugiyama SAFB2 KIAA0138 PAQPPEHAVDGEGFKNtLEtssLNFKVtPDIEEsLLEPENE
Q14157 T256 Sugiyama UBAP2L KIAA0144 NICE4 AWRtAtEEWGtEDWNEDLsEtKIFtAsNVssVPLPAENVtI
Q14192 S13 Sugiyama FHL2 DRAL SLIM3 ________MTERFDCHHCNEsLFGKKYILREESPYCVVCFE
Q14192 S257 Sugiyama FHL2 DRAL SLIM3 IsFEERQWHNDCFNCKKCsLsLVGRGFLTERDDILCPDCGK
Q14203 T714 Sugiyama DCTN1 AHERSLDFLIELLHKDQLDEtVNVEPLTKAIKYYQHLYSIH
Q14247 S432 Sugiyama CTTN EMS1 EERLPssPVyEDAAsFKAELsyRGPVsGtEPEPVysMEAAD
Q14444 T303 Sugiyama CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 YTEQSEVESTEYVNRQFMAEtQFtsGEKEQVDEWTVETVEV
Q14566 T195 Sugiyama MCM6 TQPNICRNPVCANRRRFLLDtNKSRFVDFQKVRIQETQAEL
Q14568 S164 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 VAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGT
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 S169 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 TVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILH
Q14568 S52 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14677 S166 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE
Q14694 S253 Sugiyama USP10 KIAA0190 GSDTRTAGQPEGGPGADFGQsCFPAEAGRDtLsRTAGAQPC
Q14697 S169 Sugiyama GANAB G2AN KIAA0088 IILTARPFRLDLLEDRSLLLsVNARGLLEFEHQRAPRVsQG
Q14738 S598 Sugiyama PPP2R5D DVyTIKALEAHKRAEEFLTAsQEAL________________
Q14980 S1149 Sugiyama NUMA1 NMP22 NUMA VSKLEQQCQKQQEQADsLERsLEAERASRAERDsALEtLQG
Q14980 S1181 Sugiyama NUMA1 NMP22 NUMA DsALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQD
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15043 S56 Sugiyama SLC39A14 KIAA0062 ZIP14 PAISAASFLQDLIHRYGEGDsLTLQQLKALLNHLDVGVGRG
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15056 T100 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 KFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRK
Q15084 S169 Sugiyama PDIA6 ERP5 P5 TXNDC7 GKQGRSDsSSKKDVIELtDDsFDKNVLDSEDVWMVEFYAPW
Q15084 S230 Sugiyama PDIA6 ERP5 P5 TXNDC7 QTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIFQKGEsPV
Q15084 S375 Sugiyama PDIA6 ERP5 P5 TXNDC7 GYPAMAAINARKMKFALLKGsFsEQGINEFLRELsFGRGst
Q15084 S389 Sugiyama PDIA6 ERP5 P5 TXNDC7 FALLKGsFsEQGINEFLRELsFGRGstAPVGGGAFPtIVER
Q15084 T223 Sugiyama PDIA6 ERP5 P5 TXNDC7 AAsEVKEQTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIF
Q15149 S4590 Sugiyama PLEC PLEC1 KYLTCPKTKLKISYKDALDRsMVEEGTGLRLLEAAAQstKG
Q15185 S118 Sugiyama PTGES3 P23 TEBP WLsVDFNNWKDWEDDsDEDMsNFDRFSEMMNNMGGDEDVDL
Q15185 S64 Sugiyama PTGES3 P23 TEBP sDNFKHLNEIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQ
Q15286 T64 Sugiyama RAB35 RAB1C RAY DFKIRtVEINGEKVKLQIWDtAGQERFRtITSTYYRGTHGV
Q15365 S50 Sugiyama PCBP1 GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK
Q15366 S50 Sugiyama PCBP2 GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK
Q15643 S1376 Sugiyama TRIP11 CEV14 LQEKDATIRTLQENNHRLSDsIAATSELERKEHEQTDSEIK
Q15751 S1541 Sugiyama HERC1 sDEEGYALsGRRNVDLDLAAsHRKRGPMHSQLESLSDsWAR
Q15751 S440 Sugiyama HERC1 TDGSVRACGKGSYGRLGLGDsNNQSTLKKLTFEPHRSIKKV
Q15771 T65 Sugiyama RAB30 DFMIKTVEINGEKVKLQIWDtAGQERFRSITQSYYRSANAL
Q16658 S234 Sugiyama FSCN1 FAN1 HSN SNL LEFRsGKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELF
Q16762 S35 Sugiyama TST WLAESIRTGKLGPGLRVLDAsWysPGTREARKEYLERHVPG
Q27J81 S1192 Sugiyama INF2 C14orf151 C14orf173 EDEDEEDtAPEsALDtsLDKsFsEDAVtDssGsGtLPRARG
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3ZCM7 S75 Sugiyama TUBB8 SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC
Q49A26 S540 Sugiyama GLYR1 HIBDL NDF NP60 NPAC PTPMAAAANEVYKRAKALDQsDNDMSAVyRAYIH_______
Q53EL6 S49 Sugiyama PDCD4 H731 ENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNssR
Q562R1 S240 Sugiyama ACTBL2 VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q5H9R7 S579 Sugiyama PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 IDQFGFNDEKFADQDDIGNVsFDRVSDINFTLNTNESGNIA
Q5JRX3 S997 Sugiyama PITRM1 KIAA1104 MP1 PREP FLYGLSDEMKQAHREQLFAVsHDKLLAVSDRYLGTGKSTHG
Q5SW79 S551 Sugiyama CEP170 FAM68A KAB KIAA0470 DyNRPVINEKHKDLIKDWALssAAAVMEERKPLTTSGFHHs
Q5T4S7 S2743 Sugiyama UBR4 KIAA0462 KIAA1307 RBAF600 NtPMGDKDDDDDDDADEKMQsSGIPNGGHIRQESQEQSEVD
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q6DD87 S104 Sugiyama ZNF787 HQRTHtGERPNACADCGKTFsQSSHLVQHRRIHtGEKPYAC
Q6FI81 S307 Sugiyama CIAPIN1 CUA001 PRO0915 sCPyLGMPAFKPGEKVLLsDsNLHDA_______________
Q6IQ22 T98 Sugiyama RAB12 DFKIKTVELRGKKIRLQIWDtAGQERFNsITSAYYRSAKGI
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2 T41 Sugiyama TUBA3E WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q6PEY2 T56 Sugiyama TUBA3E MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
Q6S8J3 S1065 Sugiyama POTEE A26C1A POTE2 ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 S939 Sugiyama POTEE A26C1A POTE2 VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 T41 Sugiyama TUBA1A TUBA3 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q71U36 T56 Sugiyama TUBA1A TUBA3 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36 Y432 Sugiyama TUBA1A TUBA3 GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7KZF4 S727 Sugiyama SND1 TDRD11 LEKLMENMRNDIAsHPPVEGsyAPRRGEFCIAKFVDGEWYR
Q7KZF4 S909 Sugiyama SND1 TDRD11 RLNLWRyGDFRADDADEFGysR___________________
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z417 S652 Sugiyama NUFIP2 KIAA1321 PIG1 NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI
Q7Z6J9 S189 Sugiyama TSEN54 SEN54 RRFQPSSVLsPYERQLNLDAsVQHLEDGDGKRKRSSSSPRS
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86U42 S235 Sugiyama PABPN1 PAB2 PABP2 FAyIEFSDKEsVRTSLALDEsLFRGRQIKVIPKRTNRPGIS
Q86UF2 S140 Sugiyama CTAGE6 CTAGE6P AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH
Q86V81 S8 Sugiyama ALYREF ALY BEF THOC4 _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG
Q86W92 S638 Sugiyama PPFIBP1 KIAA1230 GTRATAGPRLGWsRDLGQsNsDLDMPFAKWTKEQVCNWLME
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q86YS6 T74 Sugiyama RAB43 RAB41 DFTMKTLEIQGKRVKLQIWDtAGQERFRTITQSYYRSANGA
Q8IUD2 S824 Sugiyama ERC1 ELKS KIAA1081 RAB6IP2 KKKsAQMLEEARRREDNLNDsSQQLQDSLRKKDDRIEELEE
Q8IV08 S479 Sugiyama PLD3 QLEAIFLRDWDSPYSHDLDTsADSVGNACRLL_________
Q8IWW6 S223 Sugiyama ARHGAP12 GEGSERIHQDSEsGDELSSSsTEQIRAttPPNQGRPDsPVy
Q8IWZ3 S1131 Sugiyama ANKHD1 KIAA1085 MASK VBARP PP2500 GGDIEAQSERTKDTPLSLACsGGRQEVVDLLLARGANKEHR
Q8IX12 S1075 Sugiyama CCAR1 CARP1 DIS LQLLEEKTDEDEKTILNLENsNKsLsGELREVKKDLsQLQE
Q8IX94 S140 Sugiyama CTAGE4 AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH
Q8IXW5 S433 Sugiyama RPAP2 C1orf82 IsDPDSHFPAWREsQNsLDEsLPFRGSGTAIKPLPSYENLK
Q8N1F7 S72 Sugiyama NUP93 KIAA0095 sQETADVKASVLLGsRGLDIsHIsQRLEsLsAAtTFEPLEP
Q8N4X5 S711 Sugiyama AFAP1L2 KIAA1914 XB130 KEKRELKETLLKCTDKEVLAsLEQKLKEIDEECRGEESRRV
Q8N6H7 S368 Sugiyama ARFGAP2 ZNF289 Nbla10535 VGTFASGPPKYKDNPFsLGEsFGsRWDTDAAWGMDRVEEKE
Q8N806 S263 Sugiyama UBR7 C14orf130 QGKDDVREVKVEQNsEPCAGsssEsDLQtVFKNESLNAESK
Q8NBJ7 S264 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 AAEQDMRVLRGAsWIDtADGsANHRARVttRMGNtPDsAsD
Q8NBP7 S487 Sugiyama PCSK9 NARC1 PSEC0052 PTRMATAVARCAPDEELLsCssFSRSGKRRGERMEAQGGKL
Q8NBS9 S426 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 KKVSEHSGGRDLDSLHRFVLsQAKDEL______________
Q8NE71 S287 Sugiyama ABCF1 ABC50 YERQVASLKAANAAENDFsVsQAEMSsRQAMLENASDIKLE
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TD19 S868 Sugiyama NEK9 KIAA1995 NEK8 NERCC LQGLKVAsEAPLEHKPQVEAssPRLNPAVtCAGKGtPLtPP
Q8TF05 S57 Sugiyama PPP4R1 MEG1 PP4R1 DFVSQDEMLTPLGRLDKyAAsENIFNRQMVARSLLDTLREV
Q8WVJ2 S142 Sugiyama NUDCD2 LTLERFQKENPGFDFsGAEIsGNytKGGPDFsNLEK_____
Q8WWI1 S706 Sugiyama LMO7 FBX20 FBXO20 KIAA0858 RLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEMQK
Q8WWM7 S273 Sugiyama ATXN2L A2D A2LG A2LP A2RP PNEMFKFNEENyGVKTtyDssLssytVPLEKDNsEEFRQRE
Q92928 T64 Sugiyama RAB1C DFKIQTIELDGKTIKLQIWDtAGQERFWTITSSYYRGAHGF
Q92930 T64 Sugiyama RAB8B DFKIRTIELDGKKIKLQIWDtAGQERFRtITTAYYRGAMGI
Q969M3 S45 Sugiyama YIPF5 FINGER5 YIP1A PP12723 SB140 UNQ3123/PRO10275 SYDYGGSGGPYSKQYAGyDysQQGRFVPPDMMQPQQPYTGQ
Q96AC1 S666 Sugiyama FERMT2 KIND2 MIG2 PLEKHC1 VHEFIGGYIFLSTRAKDQNEsLDEEMFyKLTSGWV______
Q96AE4 S52 Sugiyama FUBP1 KDALQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQ
Q96AG4 S47 Sugiyama LRRC59 PRO1855 LNEVPVKELAALPKATILDLsCNKLTTLPSDFCGLtHLVKL
Q96AP0 S169 SIGNOR|PSP ACD PIP1 PTOP TINT1 TPP1 YDCLEEHLSESTSSNAGLSLsQLLDEMREDQEHQGALVCLA
Q96AX2 T86 Sugiyama RAB37 DFRNKVVTVDGVRVKLQIWDtAGQERFRSVTHAYYRDAQAL
Q96D15 S76 Sugiyama RCN3 UNQ239/PRO272 HEAFLGREVAKEFDQLtPEEsQARLGRIVDRMDRAGDGDGW
Q96DA2 T65 Sugiyama RAB39B FFSRLVEIEPGKRIKLQIWDtAGQERFRSITRAYYRNSVGG
Q96E17 T86 Sugiyama RAB3C DFKVKTVFKNEKRIKLQIWDtAGQERYRtITTAYYRGAMGF
Q96HE7 S143 Sugiyama ERO1A ERO1L UNQ434/PRO865 EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD
Q96HE7 S71 Sugiyama ERO1A ERO1L UNQ434/PRO865 ETIDRFNNYRLFPRLQKLLEsDyFRyyKVNLKRPCPFWNDI
Q96HE7 T148 Sugiyama ERO1A ERO1L UNQ434/PRO865 IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA
Q96IR7 S360 Sugiyama HPDL GLOXD1 LIQRQGATGFGQGNIRALWQsVQEQsARSQEA_________
Q96LD4 S180 Sugiyama TRIM47 GOA RNF100 ERSPALRGHRLVPPLRRLEEsLCPRHLRPLERYCRAERVCL
Q96QK1 S760 Sugiyama VPS35 MEM3 TCCCTA00141 IQVLNQLIQKIREDLPNLEssEEtEQINKHFHNtLEHLRLR
Q96R06 S716 Sugiyama SPAG5 QVSAQLEECKGQTEQLELENsRLATDLRAQLQILANMDSQL
Q96S66 S59 Sugiyama CLCC1 KIAA0761 MCLC MRKSQAKYGISGEKDVSPDLsCADEIsECyHKLDSLTYKID
Q99426 S76 Sugiyama TBCB CG22 CKAP1 LYGVDDKFYsKLDQEDALLGsYPVDDGCRIHVIDHsGARLG
Q99497 S57 Sugiyama PARK7 GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL
Q99497 T154 Sugiyama PARK7 MNGGHytysENRVEKDGLILtSRGPGTSFEFALAIVEALNG
Q99613 S639 Sugiyama EIF3C EIF3S8 CAFRQGLTKDAHNALLDIQssGRAKELLGQGLLLRSLQERN
Q99615 S94 Sugiyama DNAJC7 TPR2 TTC2 MLGRFREALGDAQQsVRLDDsFVRGHLREGKCHLSLGNAMA
Q99832 T351 Sugiyama CCT7 CCTH NIP7-1 QtSVNALSADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCt
Q99832 T458 Sugiyama CCT7 CCTH NIP7-1 yAKALEIIPRQLCDNAGFDAtNILNKLRARHAQGGTWYGVD
Q99961 S108 Sugiyama SH3GL1 CNSA1 SH3D2B QSEGLLGECMIRHGKELGGEsNFGDALLDAGEsMKRLAEVK
Q99961 S120 Sugiyama SH3GL1 CNSA1 SH3D2B HGKELGGEsNFGDALLDAGEsMKRLAEVKDSLDIEVKQNFI
Q9BQE3 S439 Sugiyama TUBA1C TUBA6 SEAREDMAALEKDyEEVGADsADGEDEGEEy__________
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3 T41 Sugiyama TUBA1C TUBA6 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q9BQE3 T56 Sugiyama TUBA1C TUBA6 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BRA2 S41 Sugiyama TXNDC17 TXNL5 QHNGKTIFAyFTGSKDAGGKsWCPDCVQAEPVVREGLKHIS
Q9BT78 S18 Sugiyama COPS4 CSN4 ___MAAAVRQDLAQLMNSsGsHKDLAGKYRQILEKAIQLSG
Q9BUJ2 T507 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 CLNRLIQIAARKKRNyILDQtNVyGsAQRRKMRPFEGFQRK
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BXP5 S703 Sugiyama SRRT ARS2 ASR2 EEAQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKFK
Q9BYX7 S239 Sugiyama POTEKP ACTBL3 FKSG30 VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9BYX7 S365 Sugiyama POTEKP ACTBL3 FKSG30 ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9C0C2 S1173 Sugiyama TNKS1BP1 KIAA1741 TAB182 KttAGsVDWTDQLGLRNLEVssCVGsGGssEAREsAVGQMG
Q9GZZ9 S24 Sugiyama UBA5 UBE1DC1 SVERLQQRVQELERELAQERsLQVPRSGDGGGGRVRIEKMs
Q9H0U4 T64 Sugiyama RAB1B DFKIRTIELDGKTIKLQIWDtAGQERFRtItsSYYRGAHGI
Q9H147 S210 Sugiyama DNTTIP1 C20orf167 TDIF1 KSCEPIRREGPKWDPARLNEsTTFVLGSRANKALGMGGTRG
Q9H173 T125 Sugiyama SIL1 UNQ545/PRO836 QYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEME
Q9H173 Y126 Sugiyama SIL1 UNQ545/PRO836 YEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEMES
Q9H1H9 S1753 Sugiyama KIF13A RBKIN HsFTEFMGVSEGKDFDGLTDssAGELssRRsLPNKTGGKTV
Q9H2M9 S455 Sugiyama RAB3GAP2 KIAA0839 TVEDLHERVPEKADFsPFGNsQGPSRVAQFLVIYAPRRGIL
Q9H2U2 S313 Sugiyama PPA2 HSPC124 VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG
Q9H3N1 S228 Sugiyama TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 PSKRRRPQPYPYPSKKLLsEsAQPLKKVEEEQEADEEDVsE
Q9H6T3 S348 Sugiyama RPAP3 KIQKYEEAEKDCTQAILLDGsYSKAFARRGTARTFLGKLNE
Q9H788 S187 Sugiyama SH2D4A PPP1R38 SH2A EEKIRSLSSSSRNIQQMLADsINRMKAYAFHQKKESMKKKQ
Q9H788 S317 Sugiyama SH2D4A PPP1R38 SH2A SGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRAGY
Q9HB07 T193 Sugiyama MYG1 C12orf10 DAVDNGISQWAEGEPRyALttTLsARVARLNPTWNHPDQDT
Q9HB71 T209 Sugiyama CACYBP S100A6BP SIP PNAS-107 EGLMNVLKKIyEDGDDDMKRtINKAWVESREKQAKGDTEF_
Q9HC35 S144 SIGNOR|PSP EML4 C2orf2 EMAPL4 GQREKKEEsHsNDQsPQIRAsPsPQPssQPLQIHRQtPEsK
Q9HC98 S206 Sugiyama NEK6 VKLGDLGLGRFFssEttAAHsLVGtPYYMSPERIHENGYNF
Q9HC98 S312 Sugiyama NEK6 QRPDIGYVHQVAKQMHIWMSst___________________
Q9HC98 S57 Sugiyama NEK6 sFRCSLADFQIEKKIGRGQFsEVyKAtCLLDRKTVALKKVQ
Q9HC98 T202 Sugiyama NEK6 ATGVVKLGDLGLGRFFssEttAAHsLVGtPYYMSPERIHEN
Q9HC98 T313 Sugiyama NEK6 RPDIGYVHQVAKQMHIWMSst____________________
Q9HC98 T63 Sugiyama NEK6 ADFQIEKKIGRGQFsEVyKAtCLLDRKTVALKKVQIFEMMD
Q9HC98 Y60 Sugiyama NEK6 CSLADFQIEKKIGRGQFsEVyKAtCLLDRKTVALKKVQIFE
Q9NP61 S455 Sugiyama ARFGAP3 ARFGAP1 RQsQADYETRARLERLsAsssIssADLFEEPRKQPAGNysL
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NQE9 T47 Sugiyama HINT3 ssVGTCEAAGKsPEPKDyDstCVFCRIAGRQDPGTELLHCE
Q9NQR4 S137 Sugiyama NIT2 CUA002 DIDVPGKITFQESKTLsPGDsFSTFDTPyCRVGLGICYDMR
Q9NRX4 T119 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 PAQHAISTEKIKAKyPDyEVtWANDGy______________
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NUQ8 S186 Sugiyama ABCF3 RLESSGKNKSYDVRIENFDVsFGDRVLLAGADVNLAWGRRY
Q9NVA2 S407 Sugiyama SEPTIN11 SEPT11 ELEEEVNNFQKKKAAAQLLQsQAQQSGAQQTKKDKDKKNAS
Q9NY33 S190 Sugiyama DPP3 TYFSGNCTMEDAKLAQDFLDsQNLsAyNtRLFKEVDGEGKP
Q9NYB9 S22 Sugiyama ABI2 ARGBPIA AELQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSAD
Q9UBC2 S518 Sugiyama EPS15L1 EPS15R LNRAKSELNRLQQEETQLEQsIQAGRVQLETIIKSLKSTQD
Q9UGV2 S349 Sugiyama NDRG3 tHstsssLGsGEsPFsRsVtsNQsDGtQESCEsPDVLDRHQ
Q9UI15 S185 Sugiyama TAGLN3 NP25 EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9UK45 S16 Sugiyama LSM7 _____MADKEKKKKEsILDLsKYIDKTIRVKFQGGREASGI
Q9UKK9 S24 Sugiyama NUDT5 NUDIX5 HSPC115 QEPtEssQNGKQyIISEELIsEGKWVKLEKTTYMDPTGKtR
Q9ULC3 S186 Sugiyama RAB23 HSPC137 AEKYLQKLKQQIAEDPELTHsssNKIGVFNtsGGsHsGQNs
Q9UNF0 S273 Sugiyama PACSIN2 KHLDLSNVAGYKAIyHDLEQsIRAADAVEDLRWFRANHGPG
Q9UNX3 S12 Sugiyama RPL26L1 RPL26P1 _________MKFNPFVtsDRsKNRKRHFNAPSHVRRKIMss
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UPN9 S949 Sugiyama TRIM33 KIAA1113 RFG7 TIF1G TFCRDIGKPEVEYDCDNLQHsKKGKTAQGLsPVDQRKCERL
Q9UPQ0 S907 Sugiyama LIMCH1 KIAA1102 TRESDRLEEKGsLTEGALAHsGNPVSKGVHEDHQLDTEAGA
Q9UQ80 T200 Sugiyama PA2G4 EBP1 TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV
Q9UQ80 T60 Sugiyama PA2G4 EBP1 ssGVsVLsLCEKGDAMIMEEtGKIFKKEKEMKKGIAFPTSI
Q9UQB8 S336 Sugiyama BAIAP2 RKAAQPKsLsPPQsQSKLSDsysNtLPVRKSVTPKNSYATt
Q9UQB8 T340 Sugiyama BAIAP2 QPKsLsPPQsQSKLSDsysNtLPVRKSVTPKNSYATtENKt
Q9UQB8 Y337 Sugiyama BAIAP2 KAAQPKsLsPPQsQSKLSDsysNtLPVRKSVTPKNSYATtE
Q9UQE7 S886 Sugiyama SMC3 BAM BMH CSPG6 SMC3L1 LEAINKRVKDTMARSEDLDNsIDKTEAGIKELQKSMERWKN
Q9Y265 S29 Sugiyama RUVBL1 INO80H NMP238 TIP49 TIP49A TTKTQRIAsHSHVKGLGLDEsGLAKQAASGLVGQENAREAC
Q9Y295 T194 Sugiyama DRG1 NEDD3 SKPPNIGFKKKDKGGINLTAtCPQSELDAETVKSILAEyKI
Q9Y2B0 S115 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF
Q9Y2B0 S63 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2X9 S778 Sugiyama ZNF281 GZP1 ZBP99 QLTPSQELDDLIDSQKNLEtsSAFQsssQKLTSQKEQKNLE
Q9Y3B8 S203 Sugiyama REXO2 SFN SMFN CGI-114 EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK
Q9Y3F4 S228 Sugiyama STRAP MAWD UNRIP FHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLy
Q9Y3F4 T225 Sugiyama STRAP MAWD UNRIP SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF
Q9Y450 S65 Sugiyama HBS1L HBS1 KIAA1038 RDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCL
Q9Y5K5 S131 Sugiyama UCHL5 UCH37 AD-019 CGI-70 LSEFKEFSQSFDAAMKGLALsNsDVIRQVHNSFARQQMFEF
Q9Y5X1 S116 Sugiyama SNX9 SH3PX1 SH3PXD3A SNNHQVGSGNDPWSAWSASKsGNWESsEGWGAQPEGAGAQR
Q9Y617 S43 Sugiyama PSAT1 PSA LEIQKELLDYKGVGIsVLEMsHRssDFAKIINNTENLVREL
Q9Y6D5 S700 Sugiyama ARFGEF2 ARFGEP2 BIG2 QFLHQEERLDSTQVGDFLGDsARFNKEVMYAYVDQLDFCEK
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Mitotic Prometaphase R-HSA-68877 1.657341e-12 11.781 1 0
Cell Cycle R-HSA-1640170 4.148126e-12 11.382 1 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.808786e-11 10.743 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.417315e-10 9.849 1 1
Attenuation phase R-HSA-3371568 2.078206e-10 9.682 0 0
Cell Cycle, Mitotic R-HSA-69278 1.894599e-10 9.722 1 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 8.408778e-10 9.075 0 0
HSF1-dependent transactivation R-HSA-3371571 2.305530e-08 7.637 0 0
G2/M Transition R-HSA-69275 6.810326e-08 7.167 0 0
HSF1 activation R-HSA-3371511 6.892807e-08 7.162 0 0
Cellular response to heat stress R-HSA-3371556 8.051432e-08 7.094 0 0
Mitotic G2-G2/M phases R-HSA-453274 9.307258e-08 7.031 0 0
Separation of Sister Chromatids R-HSA-2467813 1.115768e-07 6.952 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.716725e-07 6.765 0 0
Mitotic Anaphase R-HSA-68882 2.778956e-07 6.556 0 0
M Phase R-HSA-68886 3.092727e-07 6.510 1 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.188195e-07 6.496 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 3.280321e-07 6.484 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.127543e-07 6.213 0 0
EPH-Ephrin signaling R-HSA-2682334 6.534166e-07 6.185 0 0
Apoptotic execution phase R-HSA-75153 8.166979e-07 6.088 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 8.873161e-07 6.052 0 0
Amplification of signal from the kinetochores R-HSA-141424 8.873161e-07 6.052 0 0
Kinesins R-HSA-983189 1.177290e-06 5.929 0 0
Signaling by ERBB2 R-HSA-1227986 3.658138e-06 5.437 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.954680e-06 5.403 0 0
MITF-M-dependent gene expression R-HSA-9856651 3.993885e-06 5.399 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 7.059308e-06 5.151 0 0
Nervous system development R-HSA-9675108 8.362942e-06 5.078 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 8.899890e-06 5.051 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.121761e-05 4.950 0 0
Signal Transduction R-HSA-162582 1.067534e-05 4.972 0 0
Cell Cycle Checkpoints R-HSA-69620 1.141135e-05 4.943 0 0
PKR-mediated signaling R-HSA-9833482 1.386407e-05 4.858 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.490344e-05 4.827 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.623793e-05 4.789 0 0
Signaling by ALK in cancer R-HSA-9700206 1.623793e-05 4.789 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.164714e-05 4.665 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.164714e-05 4.665 0 0
Axon guidance R-HSA-422475 2.353778e-05 4.628 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.386782e-05 4.622 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 2.612018e-05 4.583 0 0
Centrosome maturation R-HSA-380287 3.553140e-05 4.449 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 3.597262e-05 4.444 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 3.462385e-05 4.461 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.730096e-05 4.428 0 0
MECP2 regulates transcription factors R-HSA-9022707 5.186495e-05 4.285 0 0
SOS-mediated signalling R-HSA-112412 5.186495e-05 4.285 0 0
EPHB-mediated forward signaling R-HSA-3928662 5.507414e-05 4.259 0 0
Post NMDA receptor activation events R-HSA-438064 6.145607e-05 4.211 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 6.500267e-05 4.187 0 0
mRNA Splicing R-HSA-72172 6.640631e-05 4.178 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 6.869415e-05 4.163 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 7.445791e-05 4.128 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 7.958094e-05 4.099 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 8.961138e-05 4.048 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 9.959772e-05 4.002 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.069766e-04 3.971 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 1.128438e-04 3.948 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.149423e-04 3.940 0 0
Regulation of KIT signaling R-HSA-1433559 1.285676e-04 3.891 0 0
Aggrephagy R-HSA-9646399 1.487176e-04 3.828 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.593455e-04 3.798 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.528331e-04 3.816 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.593455e-04 3.798 0 0
Semaphorin interactions R-HSA-373755 1.579355e-04 3.802 0 0
Signaling by VEGF R-HSA-194138 1.640111e-04 3.785 0 0
Chromatin organization R-HSA-4839726 1.641501e-04 3.785 0 0
Selective autophagy R-HSA-9663891 1.722671e-04 3.764 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 1.872066e-04 3.728 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.973941e-04 3.705 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.186656e-04 3.660 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.302758e-04 3.638 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 2.515550e-04 3.599 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.705999e-04 3.568 0 0
Recycling pathway of L1 R-HSA-437239 3.183591e-04 3.497 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.772687e-04 3.423 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 3.825455e-04 3.417 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 4.294978e-04 3.367 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 4.364838e-04 3.360 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 4.935384e-04 3.307 0 0
FLT3 Signaling R-HSA-9607240 5.492911e-04 3.260 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 6.117516e-04 3.213 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 6.117516e-04 3.213 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 6.692756e-04 3.174 0 0
Chromatin modifying enzymes R-HSA-3247509 6.623534e-04 3.179 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 6.810264e-04 3.167 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 7.684055e-04 3.114 0 0
Erythropoietin activates RAS R-HSA-9027284 8.478485e-04 3.072 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 8.478485e-04 3.072 0 0
Polo-like kinase mediated events R-HSA-156711 8.536347e-04 3.069 0 0
Ephrin signaling R-HSA-3928664 8.536347e-04 3.069 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 8.536347e-04 3.069 0 0
Regulation of TP53 Activity R-HSA-5633007 9.023012e-04 3.045 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 9.345019e-04 3.029 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 9.501433e-04 3.022 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.064129e-03 2.973 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 1.084452e-03 2.965 0 0
Signaling by KIT in disease R-HSA-9669938 1.084452e-03 2.965 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 1.098630e-03 2.959 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 1.105868e-03 2.956 0 0
MET activates RAS signaling R-HSA-8851805 1.154703e-03 2.938 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.204894e-03 2.919 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.138850e-03 2.944 0 0
Gap junction trafficking and regulation R-HSA-157858 1.245662e-03 2.905 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.426427e-03 2.846 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 1.527641e-03 2.816 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.527641e-03 2.816 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 1.426427e-03 2.846 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.627075e-03 2.789 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.674450e-03 2.776 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.682055e-03 2.774 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.696629e-03 2.770 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 1.736892e-03 2.760 0 0
MHC class II antigen presentation R-HSA-2132295 1.774566e-03 2.751 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.804823e-03 2.744 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.852106e-03 2.732 0 0
Nuclear Envelope Breakdown R-HSA-2980766 2.028729e-03 2.693 1 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.084806e-03 2.681 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.084806e-03 2.681 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.173300e-03 2.663 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 2.296353e-03 2.639 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.375927e-03 2.624 0 0
DAP12 signaling R-HSA-2424491 2.559703e-03 2.592 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 2.654782e-03 2.576 0 0
Signaling by SCF-KIT R-HSA-1433557 2.652615e-03 2.576 0 0
Gap junction assembly R-HSA-190861 2.654782e-03 2.576 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 2.721996e-03 2.565 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.721996e-03 2.565 0 0
Cilium Assembly R-HSA-5617833 2.838636e-03 2.547 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 3.058037e-03 2.515 0 0
Gap junction trafficking R-HSA-190828 3.167788e-03 2.499 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 3.296288e-03 2.482 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 3.358076e-03 2.474 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 3.762469e-03 2.425 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 3.795865e-03 2.421 0 0
Signaling by EGFR R-HSA-177929 3.998049e-03 2.398 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 4.008049e-03 2.397 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 4.335186e-03 2.363 0 0
Signaling by RAS mutants R-HSA-6802949 4.445449e-03 2.352 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 4.445449e-03 2.352 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 4.445449e-03 2.352 0 0
Signaling downstream of RAS mutants R-HSA-9649948 4.445449e-03 2.352 0 0
MAP2K and MAPK activation R-HSA-5674135 4.621965e-03 2.335 0 0
Signaling by RAF1 mutants R-HSA-9656223 4.621965e-03 2.335 0 0
Signaling by FGFR1 in disease R-HSA-5655302 4.621965e-03 2.335 0 0
Signaling by LTK R-HSA-9842663 4.742098e-03 2.324 0 0
Membrane Trafficking R-HSA-199991 4.880417e-03 2.312 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 5.188391e-03 2.285 0 0
Signaling by NTRKs R-HSA-166520 5.096711e-03 2.293 0 0
Metabolism of RNA R-HSA-8953854 5.525403e-03 2.258 0 0
Cellular responses to stimuli R-HSA-8953897 5.621538e-03 2.250 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 5.853107e-03 2.233 0 0
Autophagy R-HSA-9612973 5.922910e-03 2.227 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 5.926156e-03 2.227 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 5.996067e-03 2.222 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 6.113883e-03 2.214 0 0
Nef and signal transduction R-HSA-164944 6.176851e-03 2.209 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 6.176851e-03 2.209 0 0
Interleukin-12 signaling R-HSA-9020591 6.249923e-03 2.204 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 6.542902e-03 2.184 0 0
Signalling to RAS R-HSA-167044 6.621516e-03 2.179 0 0
Signal attenuation R-HSA-74749 6.758863e-03 2.170 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 6.758863e-03 2.170 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 7.517207e-03 2.124 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 6.970453e-03 2.157 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 6.970453e-03 2.157 0 0
TGFBR3 expression R-HSA-9839394 6.970453e-03 2.157 0 0
Signaling by Hippo R-HSA-2028269 7.703757e-03 2.113 0 0
Specification of primordial germ cells R-HSA-9827857 7.703757e-03 2.113 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 7.949763e-03 2.100 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 8.102143e-03 2.091 0 0
Signalling to ERKs R-HSA-187687 8.321355e-03 2.080 0 0
Signaling by EGFR in Cancer R-HSA-1643713 8.578866e-03 2.067 0 0
Myogenesis R-HSA-525793 8.578866e-03 2.067 0 0
PECAM1 interactions R-HSA-210990 9.500464e-03 2.022 0 0
L1CAM interactions R-HSA-373760 9.776697e-03 2.010 0 0
Chaperone Mediated Autophagy R-HSA-9613829 9.872949e-03 2.006 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 9.872949e-03 2.006 0 0
Notch-HLH transcription pathway R-HSA-350054 1.037833e-02 1.984 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.094753e-02 1.961 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 9.799968e-03 2.009 0 0
HIV Infection R-HSA-162906 1.102304e-02 1.958 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.057150e-02 1.976 0 0
Signaling by PTK6 R-HSA-8848021 1.050436e-02 1.979 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.050436e-02 1.979 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.045763e-02 1.981 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 9.872949e-03 2.006 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.104368e-02 1.957 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.122462e-02 1.950 0 0
DCC mediated attractive signaling R-HSA-418885 1.148461e-02 1.940 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.148461e-02 1.940 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.164152e-02 1.934 0 0
Homology Directed Repair R-HSA-5693538 1.170036e-02 1.932 0 0
Integrin signaling R-HSA-354192 1.222096e-02 1.913 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.246958e-02 1.904 0 0
Interleukin-12 family signaling R-HSA-447115 1.249964e-02 1.903 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 1.253161e-02 1.902 0 0
Macroautophagy R-HSA-1632852 1.256514e-02 1.901 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.262858e-02 1.899 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.473614e-02 1.832 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.473614e-02 1.832 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.473614e-02 1.832 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.473614e-02 1.832 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.473614e-02 1.832 0 0
Activation of RAS in B cells R-HSA-1169092 1.375294e-02 1.862 0 0
Signaling by AXIN mutants R-HSA-4839735 1.295460e-02 1.888 0 0
Signaling by AMER1 mutants R-HSA-4839748 1.295460e-02 1.888 0 0
Signaling by GSK3beta mutants R-HSA-5339716 1.295460e-02 1.888 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.446054e-02 1.840 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 1.364309e-02 1.865 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.366907e-02 1.864 0 0
HATs acetylate histones R-HSA-3214847 1.499959e-02 1.824 0 0
Apoptosis R-HSA-109581 1.545643e-02 1.811 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.552579e-02 1.809 0 0
Cellular responses to stress R-HSA-2262752 1.553908e-02 1.809 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.623104e-02 1.790 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.707434e-02 1.768 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 1.720424e-02 1.764 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 1.720424e-02 1.764 0 0
GRB2 events in EGFR signaling R-HSA-179812 1.720424e-02 1.764 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 1.720424e-02 1.764 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 1.720424e-02 1.764 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 1.720424e-02 1.764 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 1.720424e-02 1.764 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.720424e-02 1.764 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.720424e-02 1.764 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.954536e-02 1.709 0 0
Phosphorylation of Emi1 R-HSA-176417 1.954536e-02 1.709 0 0
ALK mutants bind TKIs R-HSA-9700645 1.921008e-02 1.716 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 1.909549e-02 1.719 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.984944e-02 1.702 1 1
Regulation of CDH1 Function R-HSA-9764561 2.071710e-02 1.684 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.798414e-02 1.745 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.984944e-02 1.702 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 1.909549e-02 1.719 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.053843e-02 1.687 0 0
NRAGE signals death through JNK R-HSA-193648 1.836987e-02 1.736 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 1.954536e-02 1.709 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 1.874524e-02 1.727 0 0
Downstream signal transduction R-HSA-186763 2.121145e-02 1.673 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.123318e-02 1.673 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.123318e-02 1.673 0 0
CD28 dependent Vav1 pathway R-HSA-389359 2.232496e-02 1.651 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.232496e-02 1.651 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.239482e-02 1.650 0 0
Chaperonin-mediated protein folding R-HSA-390466 2.282824e-02 1.642 0 0
Regulation of TP53 Degradation R-HSA-6804757 2.304163e-02 1.637 0 0
FLT3 signaling in disease R-HSA-9682385 2.304163e-02 1.637 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.321510e-02 1.634 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 2.321510e-02 1.634 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.321510e-02 1.634 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.336506e-02 1.631 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 2.336506e-02 1.631 0 0
Cell-Cell communication R-HSA-1500931 2.465836e-02 1.608 0 0
G0 and Early G1 R-HSA-1538133 2.484060e-02 1.605 0 0
Signaling by WNT in cancer R-HSA-4791275 2.484060e-02 1.605 0 0
Smooth Muscle Contraction R-HSA-445355 2.579708e-02 1.588 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 2.592406e-02 1.586 0 0
Diseases of Telomere Maintenance R-HSA-9673013 2.695404e-02 1.569 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 2.695404e-02 1.569 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 2.695404e-02 1.569 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 2.695404e-02 1.569 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 2.695404e-02 1.569 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 2.695404e-02 1.569 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 2.695404e-02 1.569 0 0
HIV Life Cycle R-HSA-162587 2.700902e-02 1.568 0 0
Nucleotide Excision Repair R-HSA-5696398 2.771931e-02 1.557 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 2.841779e-02 1.546 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 2.841779e-02 1.546 1 1
G2/M DNA replication checkpoint R-HSA-69478 2.841779e-02 1.546 0 0
Signaling by APC mutants R-HSA-4839744 3.397549e-02 1.469 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 3.397549e-02 1.469 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 3.397549e-02 1.469 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 3.397549e-02 1.469 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 2.838303e-02 1.547 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 2.838303e-02 1.547 0 0
Striated Muscle Contraction R-HSA-390522 3.339893e-02 1.476 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 3.217876e-02 1.492 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 3.339893e-02 1.476 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 2.889559e-02 1.539 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 3.180887e-02 1.497 0 0
Co-stimulation by CD28 R-HSA-389356 2.855734e-02 1.544 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.872132e-02 1.542 0 0
Signaling by FGFR4 in disease R-HSA-5655291 2.838303e-02 1.547 0 0
Tie2 Signaling R-HSA-210993 2.872132e-02 1.542 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 3.485109e-02 1.458 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 3.485200e-02 1.458 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 3.485200e-02 1.458 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 3.485200e-02 1.458 0 0
Signaling by ERBB4 R-HSA-1236394 3.501365e-02 1.456 0 0
G2/M DNA damage checkpoint R-HSA-69473 3.501365e-02 1.456 0 0
p38MAPK events R-HSA-171007 3.543396e-02 1.451 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 3.543396e-02 1.451 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 3.543396e-02 1.451 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 3.543396e-02 1.451 0 0
Transcription of the HIV genome R-HSA-167172 3.557317e-02 1.449 0 0
DAP12 interactions R-HSA-2172127 3.571240e-02 1.447 0 0
Heme signaling R-HSA-9707616 3.597872e-02 1.444 0 0
Signaling by Erythropoietin R-HSA-9006335 3.634753e-02 1.440 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 3.634753e-02 1.440 0 0
Adipogenesis R-HSA-9843745 3.768155e-02 1.424 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 3.837140e-02 1.416 0 0
Protein folding R-HSA-391251 3.877476e-02 1.411 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 3.923172e-02 1.406 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.933474e-02 1.405 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 3.933474e-02 1.405 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 3.933474e-02 1.405 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 3.959491e-02 1.402 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 3.959491e-02 1.402 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.959491e-02 1.402 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 3.959491e-02 1.402 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 3.959491e-02 1.402 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.959491e-02 1.402 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 4.021955e-02 1.396 0 0
Regulation of gap junction activity R-HSA-191650 4.142663e-02 1.383 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 4.142663e-02 1.383 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 4.142663e-02 1.383 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 4.179025e-02 1.379 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 4.179025e-02 1.379 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 4.179025e-02 1.379 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 4.179025e-02 1.379 0 0
Nephrin family interactions R-HSA-373753 4.179025e-02 1.379 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 4.208610e-02 1.376 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.342107e-02 1.362 0 0
Activation of RAC1 R-HSA-428540 4.342107e-02 1.362 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 4.342107e-02 1.362 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 4.352144e-02 1.361 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 4.459114e-02 1.351 0 0
Defective Base Excision Repair Associated with OGG1 R-HSA-9656249 5.588325e-02 1.253 0 0
Transport of glycerol from adipocytes to the liver by Aquaporins R-HSA-432030 5.588325e-02 1.253 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 5.232710e-02 1.281 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 5.267663e-02 1.278 0 0
RET signaling R-HSA-8853659 4.979671e-02 1.303 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 5.038624e-02 1.298 0 0
HIV Transcription Initiation R-HSA-167161 5.038624e-02 1.298 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 5.038624e-02 1.298 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 5.039686e-02 1.298 0 0
mRNA 3'-end processing R-HSA-72187 4.501324e-02 1.347 0 0
Translation initiation complex formation R-HSA-72649 5.532697e-02 1.257 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 5.168839e-02 1.287 0 0
Interleukin-15 signaling R-HSA-8983432 5.429327e-02 1.265 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 5.232710e-02 1.281 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.091549e-02 1.293 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 5.429327e-02 1.265 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.501324e-02 1.347 0 0
Intraflagellar transport R-HSA-5620924 5.609013e-02 1.251 0 0
DNA Repair R-HSA-73894 4.947759e-02 1.306 0 0
Gene expression (Transcription) R-HSA-74160 5.153026e-02 1.288 0 0
Signaling by TGFBR3 R-HSA-9839373 4.511029e-02 1.346 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 5.224118e-02 1.282 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.646103e-02 1.248 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.655097e-02 1.248 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 5.820401e-02 1.235 0 0
Signaling by PDGFR in disease R-HSA-9671555 5.820401e-02 1.235 0 0
Signaling by MET R-HSA-6806834 5.933450e-02 1.227 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 6.009833e-02 1.221 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 6.009833e-02 1.221 0 0
IRS activation R-HSA-74713 6.009833e-02 1.221 0 0
Signaling by NOTCH3 R-HSA-9012852 6.104031e-02 1.214 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 6.132180e-02 1.212 0 0
Signaling by FGFR in disease R-HSA-1226099 6.138546e-02 1.212 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 6.284635e-02 1.202 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 6.284635e-02 1.202 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 6.284635e-02 1.202 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 6.284635e-02 1.202 0 0
FGFR1 mutant receptor activation R-HSA-1839124 6.284635e-02 1.202 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 6.300301e-02 1.201 0 0
Signaling by FGFR4 R-HSA-5654743 6.300301e-02 1.201 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 6.329429e-02 1.199 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 6.713488e-02 1.173 0 0
Programmed Cell Death R-HSA-5357801 6.716330e-02 1.173 0 0
GP1b-IX-V activation signalling R-HSA-430116 6.737345e-02 1.172 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 6.737345e-02 1.172 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 6.737345e-02 1.172 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 7.084749e-02 1.150 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 7.084749e-02 1.150 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 7.099253e-02 1.149 0 0
Resolution of D-Loop Structures R-HSA-5693537 7.099253e-02 1.149 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.099253e-02 1.149 0 0
Interferon Signaling R-HSA-913531 7.106798e-02 1.148 0 0
Signaling by NOTCH1 R-HSA-1980143 7.227097e-02 1.141 0 0
Cell junction organization R-HSA-446728 7.519633e-02 1.124 0 0
Host Interactions of HIV factors R-HSA-162909 7.663064e-02 1.116 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 7.751968e-02 1.111 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 7.751968e-02 1.111 0 0
Nucleosome assembly R-HSA-774815 7.751968e-02 1.111 0 0
Signaling by FGFR3 R-HSA-5654741 7.751968e-02 1.111 0 0
IGF1R signaling cascade R-HSA-2428924 7.778202e-02 1.109 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 7.894606e-02 1.103 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 7.894606e-02 1.103 0 0
HIV Transcription Elongation R-HSA-167169 7.894606e-02 1.103 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 7.894606e-02 1.103 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 7.965355e-02 1.099 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.965355e-02 1.099 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 7.976482e-02 1.098 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 7.976482e-02 1.098 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 7.976482e-02 1.098 0 0
Dual Incision in GG-NER R-HSA-5696400 7.976482e-02 1.098 0 0
Nuclear import of Rev protein R-HSA-180746 7.976482e-02 1.098 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 8.032961e-02 1.095 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 8.049065e-02 1.094 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 8.201164e-02 1.086 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 8.201164e-02 1.086 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 1.068244e-01 0.971 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 8.440685e-02 1.074 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.033223e-01 0.986 0 0
Regulation of signaling by CBL R-HSA-912631 8.666787e-02 1.062 0 0
Negative regulation of MET activity R-HSA-6807004 1.001508e-01 0.999 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.001508e-01 0.999 0 0
Co-inhibition by CTLA4 R-HSA-389513 1.001508e-01 0.999 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 1.014894e-01 0.994 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 8.991788e-02 1.046 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.009096e-01 0.996 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.009096e-01 0.996 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 9.919223e-02 1.004 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.029360e-01 0.987 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 8.914581e-02 1.050 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.998967e-02 1.000 0 0
RNA Polymerase III Transcription R-HSA-74158 9.919223e-02 1.004 0 0
Germ layer formation at gastrulation R-HSA-9754189 8.666787e-02 1.062 0 0
Receptor Mediated Mitophagy R-HSA-8934903 8.440685e-02 1.074 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 8.419172e-02 1.075 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 9.542621e-02 1.020 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 9.542621e-02 1.020 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 9.542621e-02 1.020 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 9.542621e-02 1.020 0 0
G alpha (12/13) signalling events R-HSA-416482 8.436645e-02 1.074 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 9.915936e-02 1.004 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 9.711640e-02 1.013 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 8.454504e-02 1.073 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 8.916530e-02 1.050 0 0
ESR-mediated signaling R-HSA-8939211 1.078481e-01 0.967 0 0
Response of endothelial cells to shear stress R-HSA-9860931 9.855701e-02 1.006 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 1.065320e-01 0.973 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 8.419172e-02 1.075 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 8.133550e-02 1.090 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 8.797506e-02 1.056 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 9.542621e-02 1.020 0 0
Signaling by FGFR2 R-HSA-5654738 9.769493e-02 1.010 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 8.759326e-02 1.058 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 8.991788e-02 1.046 0 0
Developmental Biology R-HSA-1266738 9.811145e-02 1.008 0 0
Intracellular signaling by second messengers R-HSA-9006925 9.601774e-02 1.018 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.267441e-02 1.033 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 9.162938e-02 1.038 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 8.936209e-02 1.049 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.034901e-01 0.985 0 0
Long-term potentiation R-HSA-9620244 1.014894e-01 0.994 0 0
Diseases of DNA repair R-HSA-9675135 8.550453e-02 1.068 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 8.201164e-02 1.086 0 0
Interleukin-37 signaling R-HSA-9008059 8.991788e-02 1.046 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.093724e-01 0.961 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.098400e-01 0.959 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.099020e-01 0.959 0 0
Phosphorylation of the APC/C R-HSA-176412 1.118937e-01 0.951 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 1.118937e-01 0.951 0 0
NCAM signaling for neurite out-growth R-HSA-375165 1.119504e-01 0.951 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.144642e-01 0.941 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 1.144642e-01 0.941 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 1.146691e-01 0.941 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.185540e-01 0.926 0 0
Deletions in the AXIN1 gene destabilize the destruction complex R-HSA-5467345 1.185540e-01 0.926 0 0
Defective OGG1 Localization R-HSA-9657050 1.185540e-01 0.926 0 0
Deletions in the AMER1 gene destabilize the destruction complex R-HSA-5467343 1.185540e-01 0.926 0 0
Defective OGG1 Substrate Binding R-HSA-9656255 1.185540e-01 0.926 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.197901e-01 0.922 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 1.210993e-01 0.917 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.239840e-01 0.907 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.240693e-01 0.906 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.250292e-01 0.903 0 0
Nuclear RNA decay R-HSA-9930044 1.250292e-01 0.903 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 1.250292e-01 0.903 0 0
Clathrin-mediated endocytosis R-HSA-8856828 1.257085e-01 0.901 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 1.282620e-01 0.892 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 1.282620e-01 0.892 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.282620e-01 0.892 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.282620e-01 0.892 0 0
Disorders of Developmental Biology R-HSA-9675151 1.296054e-01 0.887 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.301826e-01 0.885 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 1.301826e-01 0.885 0 0
Axonal growth stimulation R-HSA-209563 1.321710e-01 0.879 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 1.321710e-01 0.879 0 0
MET activates PTPN11 R-HSA-8865999 1.321710e-01 0.879 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 1.321710e-01 0.879 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 1.321710e-01 0.879 0 0
Mitotic Prophase R-HSA-68875 1.325648e-01 0.878 1 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.327347e-01 0.877 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.329571e-01 0.876 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 1.341484e-01 0.872 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 1.341484e-01 0.872 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.341484e-01 0.872 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.341484e-01 0.872 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.341484e-01 0.872 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 1.341484e-01 0.872 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.381219e-01 0.860 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 1.385139e-01 0.859 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.391595e-01 0.856 0 0
G2/M Checkpoints R-HSA-69481 1.394042e-01 0.856 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 1.428517e-01 0.845 0 0
HIV elongation arrest and recovery R-HSA-167287 1.428517e-01 0.845 0 0
Formation of the Early Elongation Complex R-HSA-113418 1.428517e-01 0.845 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.428517e-01 0.845 0 0
MAPK family signaling cascades R-HSA-5683057 1.431276e-01 0.844 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.451932e-01 0.838 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.453970e-01 0.837 0 0
Repression of WNT target genes R-HSA-4641265 1.462328e-01 0.835 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.462328e-01 0.835 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.462328e-01 0.835 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.466417e-01 0.834 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 1.466417e-01 0.834 0 0
Metabolism of non-coding RNA R-HSA-194441 1.470422e-01 0.833 0 0
snRNP Assembly R-HSA-191859 1.470422e-01 0.833 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.470422e-01 0.833 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 1.508154e-01 0.822 0 0
Signaling by NOTCH2 R-HSA-1980145 1.518721e-01 0.819 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.530735e-01 0.815 0 0
Eukaryotic Translation Elongation R-HSA-156842 1.546887e-01 0.811 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 1.548594e-01 0.810 0 0
Defective OGG1 Substrate Processing R-HSA-9656256 2.230591e-01 0.652 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 2.230591e-01 0.652 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 2.230591e-01 0.652 0 0
UNC93B1 deficiency - HSE R-HSA-5602415 2.230591e-01 0.652 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 2.230591e-01 0.652 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 2.230591e-01 0.652 0 0
Defective F8 binding to von Willebrand factor R-HSA-9672393 2.230591e-01 0.652 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 2.230591e-01 0.652 0 0
TGFBR2 MSI Frameshift Mutants in Cancer R-HSA-3642279 2.230591e-01 0.652 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 2.230591e-01 0.652 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.758700e-01 0.755 0 0
NADE modulates death signalling R-HSA-205025 1.758700e-01 0.755 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 1.758700e-01 0.755 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.214086e-01 0.655 0 0
Enhanced binding of GP1BA variant to VWF multimer:collagen R-HSA-9845620 2.214086e-01 0.655 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 2.214086e-01 0.655 0 0
Defective binding of VWF variant to GPIb:IX:V R-HSA-9846298 2.214086e-01 0.655 0 0
Type I hemidesmosome assembly R-HSA-446107 1.635750e-01 0.786 0 0
Formation of annular gap junctions R-HSA-196025 1.635750e-01 0.786 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 1.635750e-01 0.786 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 1.946934e-01 0.711 0 0
Lipophagy R-HSA-9613354 1.946934e-01 0.711 0 0
Gap junction degradation R-HSA-190873 1.946934e-01 0.711 0 0
Formation of apoptosome R-HSA-111458 2.271051e-01 0.644 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 2.271051e-01 0.644 0 0
Regulation of the apoptosome activity R-HSA-9627069 2.271051e-01 0.644 0 0
MAPK3 (ERK1) activation R-HSA-110056 2.271051e-01 0.644 0 0
Folding of actin by CCT/TriC R-HSA-390450 2.271051e-01 0.644 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 1.684713e-01 0.773 0 0
Platelet sensitization by LDL R-HSA-432142 1.684713e-01 0.773 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 2.206941e-01 0.656 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 2.206941e-01 0.656 0 0
Interleukin receptor SHC signaling R-HSA-912526 1.639887e-01 0.785 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 1.639887e-01 0.785 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 1.639887e-01 0.785 0 0
Late endosomal microautophagy R-HSA-9615710 1.581965e-01 0.801 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.581965e-01 0.801 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 1.821594e-01 0.740 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 1.821594e-01 0.740 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 2.112493e-01 0.675 0 0
Formation of definitive endoderm R-HSA-9823730 2.112493e-01 0.675 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.818701e-01 0.740 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.932873e-01 0.714 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 2.305499e-01 0.637 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.899571e-01 0.721 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 1.777585e-01 0.750 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 1.777585e-01 0.750 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.162681e-01 0.665 0 0
Neutrophil degranulation R-HSA-6798695 1.731665e-01 0.762 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 1.777585e-01 0.750 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.889082e-01 0.724 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.889082e-01 0.724 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.162681e-01 0.665 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.626683e-01 0.789 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 1.742540e-01 0.759 0 0
Insulin receptor signalling cascade R-HSA-74751 2.049415e-01 0.688 0 0
ERK/MAPK targets R-HSA-198753 2.338264e-01 0.631 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 2.338264e-01 0.631 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.961629e-01 0.707 0 0
Spry regulation of FGF signaling R-HSA-1295596 2.206941e-01 0.656 0 0
Regulation of CDH11 function R-HSA-9762292 2.271051e-01 0.644 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 2.206864e-01 0.656 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.636577e-01 0.786 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 1.946934e-01 0.711 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.698929e-01 0.770 0 0
Platelet activation, signaling and aggregation R-HSA-76002 2.290787e-01 0.640 0 0
Netrin-1 signaling R-HSA-373752 2.155360e-01 0.666 0 0
Death Receptor Signaling R-HSA-73887 2.028545e-01 0.693 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 1.698929e-01 0.770 0 0
S Phase R-HSA-69242 2.133234e-01 0.671 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 1.662511e-01 0.779 0 0
Chromosome Maintenance R-HSA-73886 1.961009e-01 0.708 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 1.662511e-01 0.779 0 0
Interleukin-7 signaling R-HSA-1266695 2.010834e-01 0.697 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 1.581965e-01 0.801 0 0
NGF-stimulated transcription R-HSA-9031628 1.759638e-01 0.755 0 0
Signaling by FGFR1 R-HSA-5654736 1.913423e-01 0.718 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 2.262162e-01 0.645 0 0
Inhibition of PKR R-HSA-169131 2.230591e-01 0.652 0 0
Unwinding of DNA R-HSA-176974 1.946934e-01 0.711 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 1.946934e-01 0.711 0 0
RUNX2 regulates bone development R-HSA-8941326 1.812267e-01 0.742 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.719131e-01 0.765 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 2.214086e-01 0.655 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.214086e-01 0.655 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 2.010834e-01 0.697 0 0
Signaling by PDGF R-HSA-186797 1.806681e-01 0.743 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.214086e-01 0.655 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 2.338264e-01 0.631 0 0
Hemostasis R-HSA-109582 2.382163e-01 0.623 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 2.400313e-01 0.620 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 2.408903e-01 0.618 0 0
Signaling by FGFR3 in disease R-HSA-5655332 2.408903e-01 0.618 0 0
Vesicle-mediated transport R-HSA-5653656 2.420922e-01 0.616 0 0
DNA Double Strand Break Response R-HSA-5693606 2.438088e-01 0.613 0 0
Hedgehog 'off' state R-HSA-5610787 2.440754e-01 0.612 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.452790e-01 0.610 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.452790e-01 0.610 0 0
Interleukin-2 family signaling R-HSA-451927 2.463391e-01 0.608 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 2.467650e-01 0.608 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 2.467650e-01 0.608 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 2.467650e-01 0.608 0 0
Nef mediated downregulation of CD28 cell surface expression R-HSA-164939 3.151793e-01 0.501 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 3.151793e-01 0.501 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 3.151793e-01 0.501 0 0
Defective HK1 causes hexokinase deficiency (HK deficiency) R-HSA-5619056 3.151793e-01 0.501 0 0
Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) R-HSA-5619039 3.151793e-01 0.501 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 3.151793e-01 0.501 0 0
Loss of Function of SMAD4 in Cancer R-HSA-3304347 3.151793e-01 0.501 0 0
SMAD2/3 MH2 Domain Mutants in Cancer R-HSA-3315487 3.151793e-01 0.501 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 3.151793e-01 0.501 0 0
Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome R-HSA-5678420 3.151793e-01 0.501 0 0
XAV939 stabilizes AXIN R-HSA-5545619 3.151793e-01 0.501 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 3.151793e-01 0.501 0 0
SMAD4 MH2 Domain Mutants in Cancer R-HSA-3311021 3.151793e-01 0.501 0 0
Defective SLC17A5 causes Salla disease (SD) and ISSD R-HSA-5619035 3.151793e-01 0.501 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 3.151793e-01 0.501 0 0
Defective VWF binding to collagen type I R-HSA-9845622 3.151793e-01 0.501 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 3.151793e-01 0.501 0 0
Defects of platelet adhesion to exposed collagen R-HSA-9823587 2.677373e-01 0.572 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.677373e-01 0.572 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.677373e-01 0.572 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.677373e-01 0.572 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 2.677373e-01 0.572 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 3.963818e-01 0.402 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 3.963818e-01 0.402 0 0
Signalling to ERK5 R-HSA-198765 3.963818e-01 0.402 0 0
Defective F8 cleavage by thrombin R-HSA-9672391 3.963818e-01 0.402 0 0
Enhanced cleavage of VWF variant by ADAMTS13 R-HSA-9845619 3.963818e-01 0.402 0 0
Potassium transport channels R-HSA-1296067 3.963818e-01 0.402 0 0
Defective visual phototransduction due to STRA6 loss of function R-HSA-9918449 3.963818e-01 0.402 0 0
Defective VWF cleavage by ADAMTS13 variant R-HSA-9845621 3.963818e-01 0.402 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 3.963818e-01 0.402 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 3.963818e-01 0.402 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 3.963818e-01 0.402 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 3.963818e-01 0.402 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 3.963818e-01 0.402 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 3.963818e-01 0.402 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 3.140289e-01 0.503 0 0
VLDL assembly R-HSA-8866423 3.140289e-01 0.503 0 0
CREB phosphorylation R-HSA-199920 3.140289e-01 0.503 0 0
STAT5 Activation R-HSA-9645135 3.140289e-01 0.503 0 0
Erythropoietin activates STAT5 R-HSA-9027283 3.140289e-01 0.503 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 3.140289e-01 0.503 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 2.604327e-01 0.584 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 2.943268e-01 0.531 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 2.943268e-01 0.531 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 2.943268e-01 0.531 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 3.596416e-01 0.444 0 0
Netrin mediated repulsion signals R-HSA-418886 3.596416e-01 0.444 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.596416e-01 0.444 0 0
LDL remodeling R-HSA-8964041 3.596416e-01 0.444 0 0
VLDL clearance R-HSA-8964046 3.596416e-01 0.444 0 0
Disinhibition of SNARE formation R-HSA-114516 3.596416e-01 0.444 0 0
Signaling by plasma membrane FGFR1 fusions R-HSA-8853336 4.679598e-01 0.330 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 4.679598e-01 0.330 0 0
MET interacts with TNS proteins R-HSA-8875513 4.679598e-01 0.330 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 4.679598e-01 0.330 0 0
TFAP2 (AP-2) family regulates transcription of other transcription factors R-HSA-8866906 4.679598e-01 0.330 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 4.679598e-01 0.330 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 4.679598e-01 0.330 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 2.748539e-01 0.561 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 2.748539e-01 0.561 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 3.284694e-01 0.484 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 3.284694e-01 0.484 0 0
Pervasive developmental disorders R-HSA-9005895 3.284694e-01 0.484 0 0
Disorders of Nervous System Development R-HSA-9697154 3.284694e-01 0.484 0 0
Scavenging by Class F Receptors R-HSA-3000484 3.284694e-01 0.484 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 2.570397e-01 0.590 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 4.040856e-01 0.394 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 4.040856e-01 0.394 0 0
MET receptor recycling R-HSA-8875656 4.040856e-01 0.394 0 0
FGFR2 alternative splicing R-HSA-6803529 2.807714e-01 0.552 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 3.625764e-01 0.441 0 0
GAB1 signalosome R-HSA-180292 3.308790e-01 0.480 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 3.308790e-01 0.480 0 0
PKA activation R-HSA-163615 3.308790e-01 0.480 0 0
Deadenylation of mRNA R-HSA-429947 3.293257e-01 0.482 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 3.591586e-01 0.445 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 3.591586e-01 0.445 0 0
CRMPs in Sema3A signaling R-HSA-399956 3.963976e-01 0.402 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 3.963976e-01 0.402 0 0
ARMS-mediated activation R-HSA-170984 4.469971e-01 0.350 0 0
Regulated proteolysis of p75NTR R-HSA-193692 4.469971e-01 0.350 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 4.469971e-01 0.350 0 0
EGFR downregulation R-HSA-182971 3.261024e-01 0.487 0 0
Tight junction interactions R-HSA-420029 3.539242e-01 0.451 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 4.297164e-01 0.367 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 2.926198e-01 0.534 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 3.785949e-01 0.422 0 0
MET promotes cell motility R-HSA-8875878 3.421283e-01 0.466 0 0
Basigin interactions R-HSA-210991 4.154844e-01 0.381 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 4.154844e-01 0.381 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 4.154844e-01 0.381 0 0
2-LTR circle formation R-HSA-164843 4.881148e-01 0.311 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.881148e-01 0.311 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 4.881148e-01 0.311 0 0
Dual incision in TC-NER R-HSA-6782135 3.246875e-01 0.489 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.032384e-01 0.394 0 0
Regulation of BACH1 activity R-HSA-9708530 4.623484e-01 0.335 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 4.623484e-01 0.335 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 4.623484e-01 0.335 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 4.623484e-01 0.335 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 3.035976e-01 0.518 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 4.432619e-01 0.353 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 4.432619e-01 0.353 0 0
Meiotic synapsis R-HSA-1221632 3.652225e-01 0.437 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 3.652225e-01 0.437 0 0
Peptide chain elongation R-HSA-156902 3.438089e-01 0.464 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 4.706255e-01 0.327 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 4.941396e-01 0.306 0 0
Degradation of CDH1 R-HSA-9766229 4.300242e-01 0.367 0 0
Nuclear Receptor transcription pathway R-HSA-383280 4.030402e-01 0.395 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 3.818348e-01 0.418 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 3.988509e-01 0.399 0 0
Regulation of RAS by GAPs R-HSA-5658442 4.487737e-01 0.348 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 4.288750e-01 0.368 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 4.288750e-01 0.368 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 3.989510e-01 0.399 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 3.989510e-01 0.399 0 0
Formation of a pool of free 40S subunits R-HSA-72689 4.683429e-01 0.329 0 0
Regulation of endogenous retroelements R-HSA-9842860 3.562353e-01 0.448 0 0
DNA Damage Bypass R-HSA-73893 4.300242e-01 0.367 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 3.082601e-01 0.511 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 3.625764e-01 0.441 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 4.881148e-01 0.311 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 4.353407e-01 0.361 0 0
mRNA Capping R-HSA-72086 2.827797e-01 0.549 0 0
GPER1 signaling R-HSA-9634597 4.112123e-01 0.386 0 0
Activation of the pre-replicative complex R-HSA-68962 3.043023e-01 0.517 0 0
mTORC1-mediated signalling R-HSA-166208 2.807714e-01 0.552 0 0
p75NTR regulates axonogenesis R-HSA-193697 4.469971e-01 0.350 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 4.623484e-01 0.335 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 4.435227e-01 0.353 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 2.943268e-01 0.531 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 3.874074e-01 0.412 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 4.028668e-01 0.395 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 4.941396e-01 0.306 0 0
Signal amplification R-HSA-392518 4.145256e-01 0.382 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 3.146587e-01 0.502 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 4.040856e-01 0.394 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.220965e-01 0.492 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 4.974745e-01 0.303 0 0
Mitophagy R-HSA-5205647 2.634709e-01 0.579 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.741228e-01 0.562 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 4.180824e-01 0.379 0 0
Adherens junctions interactions R-HSA-418990 4.540374e-01 0.343 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.596416e-01 0.444 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 3.596416e-01 0.444 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 2.807714e-01 0.552 0 0
Diseases of mitotic cell cycle R-HSA-9675126 3.481005e-01 0.458 0 0
PI3K/AKT activation R-HSA-198203 4.881148e-01 0.311 0 0
Cell-cell junction organization R-HSA-421270 4.008877e-01 0.397 0 0
Generation of second messenger molecules R-HSA-202433 3.825705e-01 0.417 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 2.748539e-01 0.561 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 2.595647e-01 0.586 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.493137e-01 0.457 0 0
Meiosis R-HSA-1500620 3.937210e-01 0.405 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 2.827074e-01 0.549 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 3.785949e-01 0.422 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 3.138208e-01 0.503 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 4.838124e-01 0.315 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.361897e-01 0.473 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 3.963976e-01 0.402 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.993957e-01 0.524 0 0
G1 Phase R-HSA-69236 3.361897e-01 0.473 0 0
Cyclin D associated events in G1 R-HSA-69231 3.361897e-01 0.473 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.939721e-01 0.532 0 0
Circadian clock R-HSA-9909396 3.245032e-01 0.489 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 2.827797e-01 0.549 0 0
Prolonged ERK activation events R-HSA-169893 4.623484e-01 0.335 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 2.753466e-01 0.560 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.596416e-01 0.444 0 0
Adrenoceptors R-HSA-390696 4.040856e-01 0.394 0 0
Specification of the neural plate border R-HSA-9834899 3.591586e-01 0.445 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 4.469971e-01 0.350 0 0
IRS-mediated signalling R-HSA-112399 3.085543e-01 0.511 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.627293e-01 0.580 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.435556e-01 0.464 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.793356e-01 0.554 0 0
G-protein mediated events R-HSA-112040 4.736403e-01 0.325 0 0
Interleukin-2 signaling R-HSA-9020558 2.604327e-01 0.584 0 0
Oncogene Induced Senescence R-HSA-2559585 4.365742e-01 0.360 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 2.604327e-01 0.584 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 2.943268e-01 0.531 0 0
Interleukin-27 signaling R-HSA-9020956 4.881148e-01 0.311 0 0
GPVI-mediated activation cascade R-HSA-114604 4.584671e-01 0.339 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.917550e-01 0.308 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.603886e-01 0.584 0 0
Signaling by TGFB family members R-HSA-9006936 3.225666e-01 0.491 0 0
RNA Polymerase II Transcription R-HSA-73857 2.783086e-01 0.555 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 3.702194e-01 0.432 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 4.432619e-01 0.353 0 0
Signaling by NOTCH4 R-HSA-9013694 4.604465e-01 0.337 0 0
Reproduction R-HSA-1474165 3.032134e-01 0.518 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.634150e-01 0.334 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 2.807714e-01 0.552 0 0
PLC beta mediated events R-HSA-112043 3.739602e-01 0.427 0 0
Signaling by FGFR R-HSA-190236 3.061692e-01 0.514 0 0
ARL13B-mediated ciliary trafficking of INPP5E R-HSA-5624958 3.151793e-01 0.501 0 0
Manipulation of host energy metabolism R-HSA-9636667 3.151793e-01 0.501 0 0
Transport of connexins along the secretory pathway R-HSA-190827 3.151793e-01 0.501 0 0
Regulation of cortical dendrite branching R-HSA-8985801 3.963818e-01 0.402 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 3.140289e-01 0.503 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 3.596416e-01 0.444 0 0
MET activates STAT3 R-HSA-8875791 4.679598e-01 0.330 0 0
Adenosine P1 receptors R-HSA-417973 4.679598e-01 0.330 0 0
RAF activation R-HSA-5673000 2.634709e-01 0.579 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 4.469971e-01 0.350 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 2.889275e-01 0.539 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 3.548230e-01 0.450 0 0
Viral Messenger RNA Synthesis R-HSA-168325 3.739602e-01 0.427 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.483812e-01 0.458 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 3.686814e-01 0.433 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 4.997779e-01 0.301 0 0
Muscle contraction R-HSA-397014 2.677628e-01 0.572 0 0
MTOR signalling R-HSA-165159 4.433394e-01 0.353 0 0
Deubiquitination R-HSA-5688426 4.349677e-01 0.362 0 0
Mitochondrial biogenesis R-HSA-1592230 4.867424e-01 0.313 0 0
DNA strand elongation R-HSA-69190 3.481005e-01 0.458 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 4.706255e-01 0.327 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 2.748539e-01 0.561 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 2.604327e-01 0.584 0 0
Ca-dependent events R-HSA-111996 2.994444e-01 0.524 0 0
Protein methylation R-HSA-8876725 4.297164e-01 0.367 0 0
Activation of ATR in response to replication stress R-HSA-176187 3.702194e-01 0.432 0 0
Signaling by ROBO receptors R-HSA-376176 3.096382e-01 0.509 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 2.573441e-01 0.589 0 0
tRNA processing in the nucleus R-HSA-6784531 2.741228e-01 0.562 0 0
DAG and IP3 signaling R-HSA-1489509 3.548230e-01 0.450 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 3.246875e-01 0.489 0 0
Negative regulation of FLT3 R-HSA-9706369 4.623484e-01 0.335 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.600219e-01 0.585 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.332419e-01 0.363 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 2.677373e-01 0.572 0 0
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members R-HSA-111453 4.040856e-01 0.394 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 3.625764e-01 0.441 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 4.469971e-01 0.350 0 0
Calmodulin induced events R-HSA-111933 3.022695e-01 0.520 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.028668e-01 0.395 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 3.879689e-01 0.411 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 3.596416e-01 0.444 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 4.469971e-01 0.350 0 0
CaM pathway R-HSA-111997 3.022695e-01 0.520 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 3.972328e-01 0.401 0 0
Breakdown of the nuclear lamina R-HSA-352238 3.151793e-01 0.501 0 0
Oligomerization of connexins into connexons R-HSA-190704 3.151793e-01 0.501 0 0
DSCAM interactions R-HSA-376172 3.963818e-01 0.402 0 0
Intracellular oxygen transport R-HSA-8981607 4.679598e-01 0.330 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 2.616152e-01 0.582 0 0
Maturation of nucleoprotein R-HSA-9683610 3.625764e-01 0.441 0 0
Early Phase of HIV Life Cycle R-HSA-162594 4.154844e-01 0.381 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.032384e-01 0.394 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 4.277613e-01 0.369 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 3.828030e-01 0.417 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 2.807714e-01 0.552 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 4.761451e-01 0.322 0 0
Sensory processing of sound R-HSA-9659379 4.181387e-01 0.379 0 0
Potential therapeutics for SARS R-HSA-9679191 4.597001e-01 0.338 0 0
Glycolysis R-HSA-70171 4.302894e-01 0.366 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 3.625764e-01 0.441 0 0
Signaling by Hedgehog R-HSA-5358351 3.188945e-01 0.496 0 0
Histamine receptors R-HSA-390650 4.679598e-01 0.330 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 4.469971e-01 0.350 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 4.297164e-01 0.367 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 4.297164e-01 0.367 0 0
Syndecan interactions R-HSA-3000170 4.974745e-01 0.303 0 0
Diseases of Base Excision Repair R-HSA-9605308 2.677373e-01 0.572 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.596416e-01 0.444 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 2.637097e-01 0.579 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.926198e-01 0.534 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 4.881148e-01 0.311 0 0
SARS-CoV-1-host interactions R-HSA-9692914 3.249770e-01 0.488 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 4.357099e-01 0.361 0 0
Influenza Infection R-HSA-168255 3.689975e-01 0.433 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 3.904242e-01 0.408 0 0
Signaling by ALK R-HSA-201556 3.623056e-01 0.441 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 4.706255e-01 0.327 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.487737e-01 0.348 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.677373e-01 0.572 0 0
Signal regulatory protein family interactions R-HSA-391160 3.963976e-01 0.402 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 4.469971e-01 0.350 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 4.297164e-01 0.367 0 0
Mitochondrial calcium ion transport R-HSA-8949215 4.432619e-01 0.353 0 0
G1/S-Specific Transcription R-HSA-69205 4.584671e-01 0.339 0 0
XBP1(S) activates chaperone genes R-HSA-381038 4.226383e-01 0.374 0 0
Growth hormone receptor signaling R-HSA-982772 4.974745e-01 0.303 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 5.015538e-01 0.300 0 0
Signaling by Leptin R-HSA-2586552 4.881148e-01 0.311 0 0
Unfolded Protein Response (UPR) R-HSA-381119 5.018857e-01 0.299 0 0
Fanconi Anemia Pathway R-HSA-6783310 5.030133e-01 0.298 0 0
IRE1alpha activates chaperones R-HSA-381070 5.088630e-01 0.293 0 0
rRNA processing R-HSA-72312 5.097986e-01 0.293 0 0
Parasite infection R-HSA-9664407 5.132760e-01 0.290 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 5.132760e-01 0.290 0 0
Leishmania phagocytosis R-HSA-9664417 5.132760e-01 0.290 0 0
Regulation of TNFR1 signaling R-HSA-5357905 5.224524e-01 0.282 0 0
RNA Polymerase I Transcription R-HSA-73864 5.226221e-01 0.282 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 5.226427e-01 0.282 0 0
Signaling by Insulin receptor R-HSA-74752 5.229682e-01 0.282 0 0
Neurodegenerative Diseases R-HSA-8863678 5.237211e-01 0.281 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 5.237211e-01 0.281 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 5.249640e-01 0.280 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 5.249640e-01 0.280 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 5.249640e-01 0.280 0 0
Chylomicron assembly R-HSA-8963888 5.272607e-01 0.278 0 0
Bicarbonate transporters R-HSA-425381 5.272607e-01 0.278 0 0
Suppression of apoptosis R-HSA-9635465 5.272607e-01 0.278 0 0
ChREBP activates metabolic gene expression R-HSA-163765 5.272607e-01 0.278 0 0
Dissolution of Fibrin Clot R-HSA-75205 5.272607e-01 0.278 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 5.310537e-01 0.275 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 5.310537e-01 0.275 0 0
Nucleotide catabolism defects R-HSA-9735786 5.310537e-01 0.275 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 5.310537e-01 0.275 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 5.310537e-01 0.275 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 5.310537e-01 0.275 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 5.310537e-01 0.275 0 0
Signaling by MAP2K mutants R-HSA-9652169 5.310537e-01 0.275 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 5.310537e-01 0.275 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 5.310537e-01 0.275 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 5.310537e-01 0.275 0 0
ATP sensitive Potassium channels R-HSA-1296025 5.310537e-01 0.275 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 5.310537e-01 0.275 0 0
HCMV Early Events R-HSA-9609690 5.361280e-01 0.271 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 5.364043e-01 0.271 0 0
Transmission across Chemical Synapses R-HSA-112315 5.382002e-01 0.269 0 0
Signaling by Interleukins R-HSA-449147 5.389670e-01 0.268 0 0
Signaling by Nuclear Receptors R-HSA-9006931 5.390017e-01 0.268 0 0
HDACs deacetylate histones R-HSA-3214815 5.402750e-01 0.267 0 0
Diseases of Immune System R-HSA-5260271 5.433664e-01 0.265 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 5.433664e-01 0.265 0 0
Cardiogenesis R-HSA-9733709 5.457929e-01 0.263 0 0
HDMs demethylate histones R-HSA-3214842 5.492903e-01 0.260 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 5.508044e-01 0.259 0 0
PKA activation in glucagon signalling R-HSA-164378 5.547216e-01 0.256 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 5.547216e-01 0.256 0 0
Apoptotic factor-mediated response R-HSA-111471 5.547216e-01 0.256 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 5.547216e-01 0.256 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 5.547216e-01 0.256 0 0
TNF signaling R-HSA-75893 5.578941e-01 0.253 0 0
ERKs are inactivated R-HSA-202670 5.643243e-01 0.248 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 5.643243e-01 0.248 0 0
Integration of provirus R-HSA-162592 5.643243e-01 0.248 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 5.643243e-01 0.248 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 5.643243e-01 0.248 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 5.645062e-01 0.248 0 0
TCF dependent signaling in response to WNT R-HSA-201681 5.658540e-01 0.247 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 5.680290e-01 0.246 0 0
Effects of PIP2 hydrolysis R-HSA-114508 5.680290e-01 0.246 0 0
Ca2+ pathway R-HSA-4086398 5.697973e-01 0.244 0 0
Metalloprotease DUBs R-HSA-5689901 5.741191e-01 0.241 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 5.741191e-01 0.241 0 0
TRP channels R-HSA-3295583 5.741191e-01 0.241 0 0
Eukaryotic Translation Termination R-HSA-72764 5.780457e-01 0.238 0 0
Signaling by NOTCH R-HSA-157118 5.805102e-01 0.236 0 0
Translesion Synthesis by POLH R-HSA-110320 5.833358e-01 0.234 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 5.833358e-01 0.234 0 0
E2F mediated regulation of DNA replication R-HSA-113510 5.833358e-01 0.234 0 0
The NLRP3 inflammasome R-HSA-844456 5.833358e-01 0.234 0 0
Maturation of nucleoprotein R-HSA-9694631 5.833358e-01 0.234 0 0
STING mediated induction of host immune responses R-HSA-1834941 5.833358e-01 0.234 0 0
Intra-Golgi traffic R-HSA-6811438 5.835594e-01 0.234 0 0
Negative regulation of MAPK pathway R-HSA-5675221 5.835594e-01 0.234 0 0
Generic Transcription Pathway R-HSA-212436 5.847666e-01 0.233 0 0
Rab regulation of trafficking R-HSA-9007101 5.854922e-01 0.232 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 5.866687e-01 0.232 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 5.866687e-01 0.232 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 5.866687e-01 0.232 0 0
NTRK2 activates RAC1 R-HSA-9032759 5.866687e-01 0.232 0 0
Defective F9 activation R-HSA-9673221 5.866687e-01 0.232 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 5.866687e-01 0.232 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 5.866687e-01 0.232 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 5.866687e-01 0.232 0 0
Co-inhibition by BTLA R-HSA-9927353 5.866687e-01 0.232 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 5.866687e-01 0.232 0 0
Reelin signalling pathway R-HSA-8866376 5.866687e-01 0.232 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 5.866687e-01 0.232 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 5.866687e-01 0.232 0 0
Assembly of Viral Components at the Budding Site R-HSA-168316 5.866687e-01 0.232 0 0
NOD1/2 Signaling Pathway R-HSA-168638 5.896906e-01 0.229 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 5.896906e-01 0.229 0 0
PTEN Regulation R-HSA-6807070 5.923290e-01 0.227 0 0
Signaling by WNT R-HSA-195721 5.930839e-01 0.227 0 0
G1/S Transition R-HSA-69206 5.955895e-01 0.225 0 0
Cytoprotection by HMOX1 R-HSA-9707564 5.968331e-01 0.224 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 5.981560e-01 0.223 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 5.981560e-01 0.223 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 5.992490e-01 0.222 0 0
Regulation of IFNG signaling R-HSA-877312 5.992490e-01 0.222 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 5.992490e-01 0.222 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 5.992490e-01 0.222 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 5.992490e-01 0.222 0 0
Interleukin-35 Signalling R-HSA-8984722 5.992490e-01 0.222 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 5.992490e-01 0.222 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 6.029606e-01 0.220 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 6.075942e-01 0.216 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 6.088961e-01 0.215 0 0
Extension of Telomeres R-HSA-180786 6.088961e-01 0.215 0 0
PERK regulates gene expression R-HSA-381042 6.107410e-01 0.214 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 6.107505e-01 0.214 0 0
Signal transduction by L1 R-HSA-445144 6.107505e-01 0.214 0 0
Cellular Senescence R-HSA-2559583 6.155811e-01 0.211 0 0
Telomere Extension By Telomerase R-HSA-171319 6.213599e-01 0.207 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 6.213599e-01 0.207 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 6.213599e-01 0.207 0 0
TBC/RABGAPs R-HSA-8854214 6.218601e-01 0.206 0 0
Gastrulation R-HSA-9758941 6.226598e-01 0.206 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 6.249888e-01 0.204 0 0
RAB geranylgeranylation R-HSA-8873719 6.252065e-01 0.204 0 0
Ub-specific processing proteases R-HSA-5689880 6.268828e-01 0.203 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 6.319132e-01 0.199 0 0
Neurexins and neuroligins R-HSA-6794361 6.319132e-01 0.199 0 0
Adenylate cyclase activating pathway R-HSA-170660 6.320207e-01 0.199 0 0
PDH complex synthesizes acetyl-CoA from PYR R-HSA-9861559 6.320207e-01 0.199 0 0
Formation of axial mesoderm R-HSA-9796292 6.320207e-01 0.199 0 0
Interleukin-6 signaling R-HSA-1059683 6.320207e-01 0.199 0 0
Frs2-mediated activation R-HSA-170968 6.320207e-01 0.199 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 6.320207e-01 0.199 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 6.320207e-01 0.199 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 6.320207e-01 0.199 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 6.320207e-01 0.199 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 6.325156e-01 0.199 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 6.356907e-01 0.197 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 6.356907e-01 0.197 0 0
CDC6 association with the ORC:origin complex R-HSA-68689 6.356907e-01 0.197 0 0
PDE3B signalling R-HSA-165160 6.356907e-01 0.197 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 6.356907e-01 0.197 0 0
PKB-mediated events R-HSA-109703 6.356907e-01 0.197 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 6.356907e-01 0.197 0 0
NGF-independant TRKA activation R-HSA-187024 6.356907e-01 0.197 0 0
Ceramide signalling R-HSA-193681 6.356907e-01 0.197 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 6.356907e-01 0.197 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 6.356907e-01 0.197 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 6.356907e-01 0.197 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 6.356907e-01 0.197 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 6.356907e-01 0.197 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 6.369285e-01 0.196 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 6.369285e-01 0.196 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.369285e-01 0.196 0 0
Lagging Strand Synthesis R-HSA-69186 6.369285e-01 0.196 0 0
Gene Silencing by RNA R-HSA-211000 6.390558e-01 0.194 0 0
Formation of paraxial mesoderm R-HSA-9793380 6.411416e-01 0.193 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 6.436998e-01 0.191 0 0
Platelet calcium homeostasis R-HSA-418360 6.436998e-01 0.191 0 0
Integrin cell surface interactions R-HSA-216083 6.437822e-01 0.191 0 0
SARS-CoV-1 Infection R-HSA-9678108 6.459924e-01 0.190 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 6.497053e-01 0.187 0 0
Voltage gated Potassium channels R-HSA-1296072 6.508926e-01 0.186 0 0
Ovarian tumor domain proteases R-HSA-5689896 6.508926e-01 0.186 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 6.516624e-01 0.186 0 0
Neuronal System R-HSA-112316 6.545103e-01 0.184 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 6.550196e-01 0.184 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 6.566868e-01 0.183 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 6.618484e-01 0.179 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 6.618484e-01 0.179 0 0
Ribavirin ADME R-HSA-9755088 6.618484e-01 0.179 0 0
Prolactin receptor signaling R-HSA-1170546 6.626588e-01 0.179 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 6.626588e-01 0.179 0 0
NRIF signals cell death from the nucleus R-HSA-205043 6.626588e-01 0.179 0 0
cGMP effects R-HSA-418457 6.626588e-01 0.179 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 6.626588e-01 0.179 0 0
Acyl chain remodeling of CL R-HSA-1482798 6.626588e-01 0.179 0 0
P2Y receptors R-HSA-417957 6.626588e-01 0.179 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 6.651534e-01 0.177 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 6.651534e-01 0.177 0 0
Activation of BH3-only proteins R-HSA-114452 6.651534e-01 0.177 0 0
Cellular response to chemical stress R-HSA-9711123 6.753140e-01 0.170 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.783528e-01 0.169 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 6.789012e-01 0.168 0 0
Chylomicron clearance R-HSA-8964026 6.789012e-01 0.168 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 6.789012e-01 0.168 0 0
Autointegration results in viral DNA circles R-HSA-177539 6.789012e-01 0.168 0 0
Defective CHST3 causes SEDCJD R-HSA-3595172 6.789012e-01 0.168 0 0
Defective CHST14 causes EDS, musculocontractural type R-HSA-3595174 6.789012e-01 0.168 0 0
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) R-HSA-5619070 6.789012e-01 0.168 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 6.789012e-01 0.168 0 0
MET Receptor Activation R-HSA-6806942 6.789012e-01 0.168 0 0
Intracellular metabolism of fatty acids regulates insulin secretion R-HSA-434313 6.789012e-01 0.168 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 6.789012e-01 0.168 0 0
Abacavir transmembrane transport R-HSA-2161517 6.789012e-01 0.168 0 0
Defective factor VIII causes hemophilia A R-HSA-9662001 6.789012e-01 0.168 0 0
Neurofascin interactions R-HSA-447043 6.789012e-01 0.168 0 0
Glucose metabolism R-HSA-70326 6.809999e-01 0.167 0 0
LDL clearance R-HSA-8964038 6.855030e-01 0.164 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.855030e-01 0.164 0 0
Trafficking of AMPA receptors R-HSA-399719 6.857067e-01 0.164 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 6.857067e-01 0.164 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 6.865592e-01 0.163 0 0
RAS processing R-HSA-9648002 6.883105e-01 0.162 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 6.883105e-01 0.162 0 0
Opioid Signalling R-HSA-111885 6.907875e-01 0.161 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 6.912084e-01 0.160 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 6.912084e-01 0.160 0 0
G beta:gamma signalling through BTK R-HSA-8964315 6.912084e-01 0.160 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 6.912084e-01 0.160 0 0
Processive synthesis on the lagging strand R-HSA-69183 6.912084e-01 0.160 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 6.912084e-01 0.160 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 6.912084e-01 0.160 0 0
Formation of the anterior neural plate R-HSA-9823739 6.912084e-01 0.160 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.920361e-01 0.160 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 6.945897e-01 0.158 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 6.963164e-01 0.157 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 6.963164e-01 0.157 0 0
RSV-host interactions R-HSA-9833110 7.021451e-01 0.154 0 0
Base Excision Repair R-HSA-73884 7.029514e-01 0.153 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.053531e-01 0.152 0 0
Inwardly rectifying K+ channels R-HSA-1296065 7.053531e-01 0.152 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 7.059633e-01 0.151 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 7.078970e-01 0.150 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 7.078970e-01 0.150 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 7.078970e-01 0.150 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 7.149107e-01 0.146 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 7.169888e-01 0.144 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 7.169888e-01 0.144 0 0
IFNG signaling activates MAPKs R-HSA-9732724 7.169888e-01 0.144 0 0
DAG1 core M1 glycosylations R-HSA-8932506 7.169888e-01 0.144 0 0
Defective CHSY1 causes TPBS R-HSA-3595177 7.169888e-01 0.144 0 0
Recycling of eIF2:GDP R-HSA-72731 7.169888e-01 0.144 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 7.169888e-01 0.144 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 7.169888e-01 0.144 0 0
PTK6 Expression R-HSA-8849473 7.169888e-01 0.144 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 7.169888e-01 0.144 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 7.169888e-01 0.144 0 0
Activation of TRKA receptors R-HSA-187015 7.169888e-01 0.144 0 0
Regulation of PTEN localization R-HSA-8948747 7.169888e-01 0.144 0 0
CHL1 interactions R-HSA-447041 7.169888e-01 0.144 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 7.177339e-01 0.144 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 7.177339e-01 0.144 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 7.177339e-01 0.144 0 0
Atorvastatin ADME R-HSA-9754706 7.177339e-01 0.144 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 7.177339e-01 0.144 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 7.177339e-01 0.144 0 0
Activation of SMO R-HSA-5635838 7.177339e-01 0.144 0 0
Interferon gamma signaling R-HSA-877300 7.193417e-01 0.143 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 7.222823e-01 0.141 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.240924e-01 0.140 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 7.240924e-01 0.140 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 7.240924e-01 0.140 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 7.290451e-01 0.137 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 7.290451e-01 0.137 0 0
Viral Infection Pathways R-HSA-9824446 7.348196e-01 0.134 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 7.412074e-01 0.130 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 7.419301e-01 0.130 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 7.423136e-01 0.129 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 7.423136e-01 0.129 0 0
Passive transport by Aquaporins R-HSA-432047 7.423136e-01 0.129 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 7.423136e-01 0.129 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 7.423136e-01 0.129 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 7.423136e-01 0.129 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 7.423136e-01 0.129 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 7.423136e-01 0.129 0 0
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) R-HSA-9651496 7.423136e-01 0.129 0 0
Stimuli-sensing channels R-HSA-2672351 7.449754e-01 0.128 0 0
SARS-CoV-2-host interactions R-HSA-9705683 7.479507e-01 0.126 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 7.489708e-01 0.126 0 0
Formation of the nephric duct R-HSA-9830364 7.489708e-01 0.126 0 0
phospho-PLA2 pathway R-HSA-111995 7.505604e-01 0.125 0 0
DAG1 core M2 glycosylations R-HSA-8932504 7.505604e-01 0.125 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 7.505604e-01 0.125 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 7.505604e-01 0.125 0 0
Interleukin-9 signaling R-HSA-8985947 7.505604e-01 0.125 0 0
Regulation by c-FLIP R-HSA-3371378 7.505604e-01 0.125 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 7.505604e-01 0.125 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 7.505604e-01 0.125 0 0
TGFBR3 PTM regulation R-HSA-9839383 7.505604e-01 0.125 0 0
Dimerization of procaspase-8 R-HSA-69416 7.505604e-01 0.125 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 7.505604e-01 0.125 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 7.505604e-01 0.125 0 0
Interleukin-23 signaling R-HSA-9020933 7.505604e-01 0.125 0 0
Selenocysteine synthesis R-HSA-2408557 7.519172e-01 0.124 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 7.528957e-01 0.123 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 7.546566e-01 0.122 0 0
Developmental Cell Lineages R-HSA-9734767 7.572763e-01 0.121 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 7.588769e-01 0.120 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 7.588769e-01 0.120 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 7.621313e-01 0.118 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 7.650358e-01 0.116 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 7.650358e-01 0.116 0 0
Aquaporin-mediated transport R-HSA-445717 7.657905e-01 0.116 0 0
MAP kinase activation R-HSA-450294 7.657905e-01 0.116 0 0
MET activates PTK2 signaling R-HSA-8874081 7.677040e-01 0.115 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 7.677040e-01 0.115 0 0
Response of Mtb to phagocytosis R-HSA-9637690 7.694767e-01 0.114 0 0
Viral mRNA Translation R-HSA-192823 7.720535e-01 0.112 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.732537e-01 0.112 0 0
Regulation of mitotic cell cycle R-HSA-453276 7.776217e-01 0.109 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 7.776217e-01 0.109 0 0
Interleukin-21 signaling R-HSA-9020958 7.801515e-01 0.108 0 0
WNT mediated activation of DVL R-HSA-201688 7.801515e-01 0.108 0 0
CASP8 activity is inhibited R-HSA-5218900 7.801515e-01 0.108 0 0
Calcineurin activates NFAT R-HSA-2025928 7.801515e-01 0.108 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 7.801515e-01 0.108 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 7.801515e-01 0.108 0 0
MAPK1 (ERK2) activation R-HSA-112411 7.801515e-01 0.108 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 7.801515e-01 0.108 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 7.801515e-01 0.108 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 7.801515e-01 0.108 0 0
Cellular response to mitochondrial stress R-HSA-9840373 7.801515e-01 0.108 0 0
HCMV Infection R-HSA-9609646 7.821500e-01 0.107 0 0
Co-inhibition by PD-1 R-HSA-389948 7.825237e-01 0.107 0 0
RMTs methylate histone arginines R-HSA-3214858 7.836046e-01 0.106 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 7.852806e-01 0.105 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 7.852806e-01 0.105 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.852806e-01 0.105 0 0
Insulin processing R-HSA-264876 7.852806e-01 0.105 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 7.855547e-01 0.105 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 7.859953e-01 0.105 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 7.859953e-01 0.105 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 7.859953e-01 0.105 0 0
Nephron development R-HSA-9831926 7.859953e-01 0.105 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 7.859953e-01 0.105 0 0
Potassium Channels R-HSA-1296071 7.898176e-01 0.102 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 7.901612e-01 0.102 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 7.970522e-01 0.099 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 7.970522e-01 0.099 0 0
Telomere Maintenance R-HSA-157579 7.992518e-01 0.097 0 0
Switching of origins to a post-replicative state R-HSA-69052 7.997308e-01 0.097 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 8.017407e-01 0.096 0 0
Inflammasomes R-HSA-622312 8.017407e-01 0.096 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.021153e-01 0.096 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 8.046636e-01 0.094 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 8.052905e-01 0.094 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 8.052905e-01 0.094 0 0
Rap1 signalling R-HSA-392517 8.052905e-01 0.094 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 8.052905e-01 0.094 0 0
Diseases of hemostasis R-HSA-9671793 8.052905e-01 0.094 0 0
Other interleukin signaling R-HSA-449836 8.052905e-01 0.094 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 8.062336e-01 0.094 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 8.062336e-01 0.094 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 8.062336e-01 0.094 0 0
DNA replication initiation R-HSA-68952 8.062336e-01 0.094 0 0
Arachidonate production from DAG R-HSA-426048 8.062336e-01 0.094 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 8.062336e-01 0.094 0 0
Defective factor IX causes hemophilia B R-HSA-9668250 8.062336e-01 0.094 0 0
Pexophagy R-HSA-9664873 8.062336e-01 0.094 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 8.062336e-01 0.094 0 0
Maturation of spike protein R-HSA-9683686 8.062336e-01 0.094 0 0
Platelet homeostasis R-HSA-418346 8.088350e-01 0.092 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 8.098336e-01 0.092 0 0
Parasitic Infection Pathways R-HSA-9824443 8.142099e-01 0.089 0 0
Leishmania infection R-HSA-9658195 8.142099e-01 0.089 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 8.161729e-01 0.088 0 0
Termination of translesion DNA synthesis R-HSA-5656169 8.171274e-01 0.088 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 8.171274e-01 0.088 0 0
DARPP-32 events R-HSA-180024 8.171274e-01 0.088 0 0
FOXO-mediated transcription R-HSA-9614085 8.171835e-01 0.088 0 0
Synthesis of DNA R-HSA-69239 8.173110e-01 0.088 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.181053e-01 0.087 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 8.184365e-01 0.087 0 0
Iron uptake and transport R-HSA-917937 8.201448e-01 0.086 0 0
Ribosome-associated quality control R-HSA-9948299 8.207081e-01 0.086 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 8.230211e-01 0.085 0 0
Signaling by NODAL R-HSA-1181150 8.230211e-01 0.085 0 0
Creatine metabolism R-HSA-71288 8.230211e-01 0.085 0 0
Glycogen synthesis R-HSA-3322077 8.230211e-01 0.085 0 0
Protein-protein interactions at synapses R-HSA-6794362 8.276353e-01 0.082 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 8.292228e-01 0.081 0 0
DAG1 core M3 glycosylations R-HSA-8932505 8.292228e-01 0.081 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 8.292228e-01 0.081 0 0
vRNP Assembly R-HSA-192905 8.292228e-01 0.081 0 0
vRNA Synthesis R-HSA-192814 8.292228e-01 0.081 0 0
Synthesis of PI R-HSA-1483226 8.292228e-01 0.081 0 0
Transport of RCbl within the body R-HSA-9758890 8.292228e-01 0.081 0 0
Prostanoid ligand receptors R-HSA-391908 8.292228e-01 0.081 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.308866e-01 0.080 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 8.314866e-01 0.080 0 0
G-protein activation R-HSA-202040 8.392868e-01 0.076 0 0
Intrinsic Pathway of Fibrin Clot Formation R-HSA-140837 8.392868e-01 0.076 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 8.392868e-01 0.076 0 0
Cellular response to starvation R-HSA-9711097 8.430233e-01 0.074 0 0
Cargo concentration in the ER R-HSA-5694530 8.448656e-01 0.073 0 0
Regulation of beta-cell development R-HSA-186712 8.475047e-01 0.072 0 0
DS-GAG biosynthesis R-HSA-2022923 8.494857e-01 0.071 0 0
Scavenging by Class H Receptors R-HSA-3000497 8.494857e-01 0.071 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 8.494857e-01 0.071 0 0
Anchoring fibril formation R-HSA-2214320 8.494857e-01 0.071 0 0
Proton-coupled monocarboxylate transport R-HSA-433692 8.494857e-01 0.071 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 8.494857e-01 0.071 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 8.494857e-01 0.071 0 0
NF-kB is activated and signals survival R-HSA-209560 8.494857e-01 0.071 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 8.494857e-01 0.071 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 8.494857e-01 0.071 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 8.494857e-01 0.071 0 0
Assembly Of The HIV Virion R-HSA-175474 8.541854e-01 0.068 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 8.542066e-01 0.068 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 8.542066e-01 0.068 0 0
Maturation of spike protein R-HSA-9694548 8.542066e-01 0.068 0 0
Platelet degranulation R-HSA-114608 8.543454e-01 0.068 0 0
PI3K Cascade R-HSA-109704 8.546375e-01 0.068 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.555205e-01 0.068 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 8.573123e-01 0.067 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 8.573123e-01 0.067 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 8.602451e-01 0.065 0 0
Interleukin-17 signaling R-HSA-448424 8.602451e-01 0.065 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 8.623565e-01 0.064 0 0
Meiotic recombination R-HSA-912446 8.643540e-01 0.063 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.648044e-01 0.063 0 0
Translation of Structural Proteins R-HSA-9683701 8.648044e-01 0.063 0 0
Integration of energy metabolism R-HSA-163685 8.665685e-01 0.062 0 0
p75NTR recruits signalling complexes R-HSA-209543 8.673454e-01 0.062 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 8.673454e-01 0.062 0 0
Polymerase switching R-HSA-69091 8.673454e-01 0.062 0 0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA R-HSA-77305 8.673454e-01 0.062 0 0
Leading Strand Synthesis R-HSA-69109 8.673454e-01 0.062 0 0
Beta oxidation of myristoyl-CoA to lauroyl-CoA R-HSA-77285 8.673454e-01 0.062 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 8.673454e-01 0.062 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 8.673454e-01 0.062 0 0
VLDLR internalisation and degradation R-HSA-8866427 8.673454e-01 0.062 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.673454e-01 0.062 0 0
Synthesis of GDP-mannose R-HSA-446205 8.673454e-01 0.062 0 0
Metallothioneins bind metals R-HSA-5661231 8.673454e-01 0.062 0 0
Reversal of alkylation damage by DNA dioxygenases R-HSA-73943 8.673454e-01 0.062 0 0
OAS antiviral response R-HSA-8983711 8.673454e-01 0.062 0 0
Free fatty acid receptors R-HSA-444209 8.678124e-01 0.062 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 8.678124e-01 0.062 0 0
G-protein beta:gamma signalling R-HSA-397795 8.688752e-01 0.061 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 8.735181e-01 0.059 0 0
Orc1 removal from chromatin R-HSA-68949 8.735181e-01 0.059 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 8.743393e-01 0.058 0 0
GABA B receptor activation R-HSA-977444 8.747343e-01 0.058 0 0
Activation of GABAB receptors R-HSA-991365 8.747343e-01 0.058 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.747343e-01 0.058 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 8.763549e-01 0.057 0 0
PPARA activates gene expression R-HSA-1989781 8.773160e-01 0.057 0 0
Post-translational protein phosphorylation R-HSA-8957275 8.792885e-01 0.056 0 0
Regulation of insulin secretion R-HSA-422356 8.792885e-01 0.056 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 8.792885e-01 0.056 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 8.792885e-01 0.056 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 8.792885e-01 0.056 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 8.796026e-01 0.056 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 8.799013e-01 0.056 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 8.821513e-01 0.054 0 0
Nucleotide biosynthesis R-HSA-8956320 8.821513e-01 0.054 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 8.823573e-01 0.054 0 0
Chylomicron remodeling R-HSA-8963901 8.830868e-01 0.054 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 8.830868e-01 0.054 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 8.830868e-01 0.054 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 8.830868e-01 0.054 0 0
Diseases of nucleotide metabolism R-HSA-9735804 8.830868e-01 0.054 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 8.830868e-01 0.054 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 8.830868e-01 0.054 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 8.830868e-01 0.054 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 8.830868e-01 0.054 0 0
Extracellular matrix organization R-HSA-1474244 8.840282e-01 0.054 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.875501e-01 0.052 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 8.895418e-01 0.051 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 8.895418e-01 0.051 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 8.895418e-01 0.051 0 0
Thromboxane signalling through TP receptor R-HSA-428930 8.916152e-01 0.050 0 0
Interleukin-6 family signaling R-HSA-6783589 8.916152e-01 0.050 0 0
Complex III assembly R-HSA-9865881 8.916152e-01 0.050 0 0
Plasma lipoprotein assembly R-HSA-8963898 8.916152e-01 0.050 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 8.916152e-01 0.050 0 0
Retrograde neurotrophin signalling R-HSA-177504 8.969611e-01 0.047 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 8.969611e-01 0.047 0 0
Hydrolysis of LPC R-HSA-1483115 8.969611e-01 0.047 0 0
Removal of the Flap Intermediate R-HSA-69166 8.969611e-01 0.047 0 0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA R-HSA-77310 8.969611e-01 0.047 0 0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA R-HSA-77350 8.969611e-01 0.047 0 0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA R-HSA-77348 8.969611e-01 0.047 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 8.969611e-01 0.047 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 8.969611e-01 0.047 0 0
Malate-aspartate shuttle R-HSA-9856872 8.969611e-01 0.047 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.969611e-01 0.047 0 0
Glycerophospholipid catabolism R-HSA-6814848 8.969611e-01 0.047 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 8.969611e-01 0.047 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 8.969611e-01 0.047 0 0
G alpha (z) signalling events R-HSA-418597 8.979125e-01 0.047 0 0
MyD88-independent TLR4 cascade R-HSA-166166 9.003716e-01 0.046 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 9.003716e-01 0.046 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 9.019629e-01 0.045 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 9.019629e-01 0.045 0 0
G protein gated Potassium channels R-HSA-1296059 9.019629e-01 0.045 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.019629e-01 0.045 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 9.019629e-01 0.045 0 0
Hyaluronan degradation R-HSA-2160916 9.019629e-01 0.045 0 0
Laminin interactions R-HSA-3000157 9.019629e-01 0.045 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 9.019629e-01 0.045 0 0
UCH proteinases R-HSA-5689603 9.039620e-01 0.044 0 0
Ion homeostasis R-HSA-5578775 9.050841e-01 0.043 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.068342e-01 0.042 0 0
PRC2 methylates histones and DNA R-HSA-212300 9.072413e-01 0.042 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 9.072413e-01 0.042 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 9.082327e-01 0.042 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 9.082327e-01 0.042 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 9.091896e-01 0.041 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 9.091896e-01 0.041 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 9.091896e-01 0.041 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 9.091896e-01 0.041 0 0
p75NTR signals via NF-kB R-HSA-193639 9.091896e-01 0.041 0 0
Translesion synthesis by REV1 R-HSA-110312 9.091896e-01 0.041 0 0
Signaling by Activin R-HSA-1502540 9.091896e-01 0.041 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 9.091896e-01 0.041 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 9.091896e-01 0.041 0 0
Other semaphorin interactions R-HSA-416700 9.091896e-01 0.041 0 0
DNA Damage Reversal R-HSA-73942 9.091896e-01 0.041 0 0
Translation of Structural Proteins R-HSA-9694635 9.099800e-01 0.041 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 9.113818e-01 0.040 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.113818e-01 0.040 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.113818e-01 0.040 0 0
Synthesis of PA R-HSA-1483166 9.118120e-01 0.040 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 9.118354e-01 0.040 0 0
SARS-CoV Infections R-HSA-9679506 9.118455e-01 0.040 0 0
Adaptive Immune System R-HSA-1280218 9.133995e-01 0.039 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 9.136852e-01 0.039 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 9.150907e-01 0.039 0 0
Regulated Necrosis R-HSA-5218859 9.162372e-01 0.038 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.199467e-01 0.036 0 0
Translesion synthesis by POLI R-HSA-5656121 9.199675e-01 0.036 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 9.199675e-01 0.036 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 9.199675e-01 0.036 0 0
Killing mechanisms R-HSA-9664420 9.199675e-01 0.036 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 9.199675e-01 0.036 0 0
Phase 4 - resting membrane potential R-HSA-5576886 9.199675e-01 0.036 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 9.199675e-01 0.036 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 9.199675e-01 0.036 0 0
Virus Assembly and Release R-HSA-168268 9.199675e-01 0.036 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 9.217850e-01 0.035 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 9.217850e-01 0.035 0 0
Gluconeogenesis R-HSA-70263 9.219914e-01 0.035 0 0
Depurination R-HSA-73927 9.223303e-01 0.035 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 9.228729e-01 0.035 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.240216e-01 0.034 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.240216e-01 0.034 0 0
G alpha (q) signalling events R-HSA-416476 9.245281e-01 0.034 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.272013e-01 0.033 0 0
COPII-mediated vesicle transport R-HSA-204005 9.272013e-01 0.033 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 9.272013e-01 0.033 0 0
Insulin receptor recycling R-HSA-77387 9.277275e-01 0.033 0 0
Prednisone ADME R-HSA-9757110 9.277275e-01 0.033 0 0
Pyrimidine salvage R-HSA-73614 9.277275e-01 0.033 0 0
Pyroptosis R-HSA-5620971 9.277275e-01 0.033 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 9.284297e-01 0.032 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 9.290006e-01 0.032 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.290006e-01 0.032 0 0
Pentose phosphate pathway R-HSA-71336 9.290006e-01 0.032 0 0
Translesion synthesis by POLK R-HSA-5655862 9.294667e-01 0.032 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 9.294667e-01 0.032 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 9.294667e-01 0.032 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 9.294667e-01 0.032 0 0
Scavenging by Class B Receptors R-HSA-3000471 9.294667e-01 0.032 0 0
Vitamin B6 activation to pyridoxal phosphate R-HSA-964975 9.294667e-01 0.032 0 0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids R-HSA-77288 9.294667e-01 0.032 0 0
Phase 2 - plateau phase R-HSA-5576893 9.294667e-01 0.032 0 0
Fibronectin matrix formation R-HSA-1566977 9.294667e-01 0.032 0 0
Synthesis of PG R-HSA-1483148 9.294667e-01 0.032 0 0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA R-HSA-77346 9.294667e-01 0.032 0 0
Galactose catabolism R-HSA-70370 9.294667e-01 0.032 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 9.294667e-01 0.032 0 0
Response to metal ions R-HSA-5660526 9.294667e-01 0.032 0 0
Hedgehog 'on' state R-HSA-5632684 9.321939e-01 0.030 0 0
Azathioprine ADME R-HSA-9748787 9.337535e-01 0.030 0 0
DNA methylation R-HSA-5334118 9.347897e-01 0.029 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 9.347897e-01 0.029 0 0
Regulation of pyruvate dehydrogenase (PDH) complex R-HSA-204174 9.347897e-01 0.029 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 9.351404e-01 0.029 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 9.351404e-01 0.029 0 0
Glycogen metabolism R-HSA-8982491 9.351404e-01 0.029 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 9.353360e-01 0.029 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.368810e-01 0.028 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 9.378390e-01 0.028 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 9.378390e-01 0.028 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 9.378390e-01 0.028 0 0
Catecholamine biosynthesis R-HSA-209905 9.378390e-01 0.028 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 9.378390e-01 0.028 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 9.378390e-01 0.028 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 9.378390e-01 0.028 0 0
Uptake and function of anthrax toxins R-HSA-5210891 9.378390e-01 0.028 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 9.378390e-01 0.028 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 9.390837e-01 0.027 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 9.395277e-01 0.027 0 0
Mitochondrial protein import R-HSA-1268020 9.395277e-01 0.027 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.407867e-01 0.027 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 9.411942e-01 0.026 0 0
Neurotransmitter clearance R-HSA-112311 9.411942e-01 0.026 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.411942e-01 0.026 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.411942e-01 0.026 0 0
Ion channel transport R-HSA-983712 9.421265e-01 0.026 0 0
TCR signaling R-HSA-202403 9.426410e-01 0.026 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.438845e-01 0.025 0 0
Protein localization R-HSA-9609507 9.441690e-01 0.025 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.442410e-01 0.025 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 9.452179e-01 0.024 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 9.452179e-01 0.024 0 0
Presynaptic function of Kainate receptors R-HSA-500657 9.452179e-01 0.024 0 0
Synaptic adhesion-like molecules R-HSA-8849932 9.452179e-01 0.024 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.452179e-01 0.024 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.452179e-01 0.024 0 0
Mismatch Repair R-HSA-5358508 9.452179e-01 0.024 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.459743e-01 0.024 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.459743e-01 0.024 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.464370e-01 0.024 0 0
Budding and maturation of HIV virion R-HSA-162588 9.469976e-01 0.024 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 9.469976e-01 0.024 0 0
Toll-like Receptor Cascades R-HSA-168898 9.473643e-01 0.023 0 0
Ion transport by P-type ATPases R-HSA-936837 9.482193e-01 0.023 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 9.484002e-01 0.023 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.484002e-01 0.023 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.486252e-01 0.023 0 0
Inositol phosphate metabolism R-HSA-1483249 9.492148e-01 0.023 0 0
Collagen formation R-HSA-1474290 9.498755e-01 0.022 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.507366e-01 0.022 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.509947e-01 0.022 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 9.517212e-01 0.021 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 9.517212e-01 0.021 0 0
Pyrimidine biosynthesis R-HSA-500753 9.517212e-01 0.021 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.517212e-01 0.021 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 9.517212e-01 0.021 0 0
Cellular response to hypoxia R-HSA-1234174 9.521260e-01 0.021 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 9.522460e-01 0.021 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.525803e-01 0.021 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.541171e-01 0.020 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.554351e-01 0.020 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.554351e-01 0.020 0 0
SLC transporter disorders R-HSA-5619102 9.556830e-01 0.020 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 9.561690e-01 0.019 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 9.564227e-01 0.019 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 9.570068e-01 0.019 0 0
Recycling of bile acids and salts R-HSA-159418 9.570068e-01 0.019 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.571401e-01 0.019 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.574529e-01 0.019 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.574529e-01 0.019 0 0
Protein hydroxylation R-HSA-9629569 9.574529e-01 0.019 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 9.574529e-01 0.019 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.578326e-01 0.019 0 0
Amine ligand-binding receptors R-HSA-375280 9.591082e-01 0.018 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.591450e-01 0.018 0 0
Kidney development R-HSA-9830369 9.591450e-01 0.018 0 0
Diseases of programmed cell death R-HSA-9645723 9.603668e-01 0.018 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.604018e-01 0.018 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.613057e-01 0.017 0 0
Heme degradation R-HSA-189483 9.613057e-01 0.017 0 0
Immune System R-HSA-168256 9.614867e-01 0.017 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.622891e-01 0.017 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 9.625044e-01 0.017 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 9.625044e-01 0.017 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.625044e-01 0.017 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 9.625044e-01 0.017 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.625044e-01 0.017 0 0
Somitogenesis R-HSA-9824272 9.627746e-01 0.016 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.627746e-01 0.016 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.627746e-01 0.016 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 9.648760e-01 0.016 0 0
eNOS activation R-HSA-203615 9.651902e-01 0.015 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.651902e-01 0.015 0 0
Hyaluronan metabolism R-HSA-2142845 9.651902e-01 0.015 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.661299e-01 0.015 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.661299e-01 0.015 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.661299e-01 0.015 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.661299e-01 0.015 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 9.661299e-01 0.015 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.669360e-01 0.015 0 0
CS-GAG biosynthesis R-HSA-2022870 9.669564e-01 0.015 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 9.669564e-01 0.015 0 0
DNA Replication Pre-Initiation R-HSA-69002 9.679292e-01 0.014 0 0
Regulation of Apoptosis R-HSA-169911 9.686981e-01 0.014 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.686981e-01 0.014 0 0
Peroxisomal protein import R-HSA-9033241 9.691740e-01 0.014 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.708800e-01 0.013 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 9.708800e-01 0.013 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 9.708800e-01 0.013 0 0
WNT ligand biogenesis and trafficking R-HSA-3238698 9.708800e-01 0.013 0 0
Reactions specific to the complex N-glycan synthesis pathway R-HSA-975578 9.708800e-01 0.013 0 0
Ethanol oxidation R-HSA-71384 9.708800e-01 0.013 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.709955e-01 0.013 0 0
GABA receptor activation R-HSA-977443 9.717622e-01 0.012 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.717622e-01 0.012 0 0
Triglyceride catabolism R-HSA-163560 9.718640e-01 0.012 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.718640e-01 0.012 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.718640e-01 0.012 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.724442e-01 0.012 0 0
PI Metabolism R-HSA-1483255 9.729949e-01 0.012 0 0
Termination of O-glycan biosynthesis R-HSA-977068 9.743379e-01 0.011 0 0
Interleukin-20 family signaling R-HSA-8854691 9.743379e-01 0.011 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 9.743379e-01 0.011 0 0
Formation of the ureteric bud R-HSA-9830674 9.743379e-01 0.011 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.743379e-01 0.011 0 0
ABC transporters in lipid homeostasis R-HSA-1369062 9.743379e-01 0.011 0 0
Biosynthesis of maresins R-HSA-9018682 9.743379e-01 0.011 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.744116e-01 0.011 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.745634e-01 0.011 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.745634e-01 0.011 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 9.745634e-01 0.011 0 0
Degradation of AXIN R-HSA-4641257 9.747197e-01 0.011 0 0
Cleavage of the damaged purine R-HSA-110331 9.747197e-01 0.011 0 0
Degradation of DVL R-HSA-4641258 9.747197e-01 0.011 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.747197e-01 0.011 0 0
Collagen chain trimerization R-HSA-8948216 9.747197e-01 0.011 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.772941e-01 0.010 0 0
Purine salvage R-HSA-74217 9.772941e-01 0.010 0 0
Mitochondrial RNA degradation R-HSA-9836573 9.773854e-01 0.010 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.773854e-01 0.010 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.783574e-01 0.010 0 0
The phototransduction cascade R-HSA-2514856 9.790328e-01 0.009 0 0
Stabilization of p53 R-HSA-69541 9.796138e-01 0.009 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.800712e-01 0.009 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 9.800712e-01 0.009 0 0
Acyl chain remodelling of PS R-HSA-1482801 9.800712e-01 0.009 0 0
Retinoid cycle disease events R-HSA-2453864 9.800712e-01 0.009 0 0
Diseases of the neuronal system R-HSA-9675143 9.800712e-01 0.009 0 0
Diseases associated with visual transduction R-HSA-2474795 9.800712e-01 0.009 0 0
Interleukin-1 family signaling R-HSA-446652 9.807063e-01 0.008 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.810566e-01 0.008 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.814695e-01 0.008 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.817029e-01 0.008 0 0
DNA Replication R-HSA-69306 9.818634e-01 0.008 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 9.824381e-01 0.008 0 0
Abacavir ADME R-HSA-2161522 9.824381e-01 0.008 0 0
Sphingolipid catabolism R-HSA-9845614 9.824381e-01 0.008 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.826583e-01 0.008 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.826583e-01 0.008 0 0
PCP/CE pathway R-HSA-4086400 9.835202e-01 0.007 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 9.835835e-01 0.007 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.843593e-01 0.007 0 0
Cristae formation R-HSA-8949613 9.845240e-01 0.007 0 0
Signaling by BMP R-HSA-201451 9.845240e-01 0.007 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 9.845240e-01 0.007 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.845240e-01 0.007 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 9.845240e-01 0.007 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.847809e-01 0.007 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.848673e-01 0.007 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.852757e-01 0.006 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.852757e-01 0.006 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.852757e-01 0.006 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.852757e-01 0.006 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.852757e-01 0.006 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 9.863623e-01 0.006 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.879823e-01 0.005 0 0
Glucagon-type ligand receptors R-HSA-420092 9.879823e-01 0.005 0 0
Defective pyroptosis R-HSA-9710421 9.881658e-01 0.005 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 9.883123e-01 0.005 0 0
Dectin-2 family R-HSA-5621480 9.883748e-01 0.005 0 0
Cardiac conduction R-HSA-5576891 9.888875e-01 0.005 0 0
Surfactant metabolism R-HSA-5683826 9.893954e-01 0.005 0 0
FCGR activation R-HSA-2029481 9.894260e-01 0.005 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.894774e-01 0.005 0 0
Formation of the cornified envelope R-HSA-6809371 9.902951e-01 0.004 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.904999e-01 0.004 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.906681e-01 0.004 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.906681e-01 0.004 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.906681e-01 0.004 0 0
Selenoamino acid metabolism R-HSA-2408522 9.910116e-01 0.004 0 0
tRNA Aminoacylation R-HSA-379724 9.913882e-01 0.004 0 0
DAG1 glycosylations R-HSA-8931838 9.917768e-01 0.004 0 0
Nucleotide salvage R-HSA-8956321 9.922132e-01 0.003 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.922132e-01 0.003 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.923821e-01 0.003 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 9.923821e-01 0.003 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.927539e-01 0.003 0 0
HCMV Late Events R-HSA-9610379 9.929355e-01 0.003 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.931811e-01 0.003 0 0
CS/DS degradation R-HSA-2024101 9.936149e-01 0.003 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.936149e-01 0.003 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.936149e-01 0.003 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.938978e-01 0.003 0 0
ER-Phagosome pathway R-HSA-1236974 9.942295e-01 0.003 0 0
Neddylation R-HSA-8951664 9.942904e-01 0.002 0 0
tRNA processing R-HSA-72306 9.943614e-01 0.002 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.943736e-01 0.002 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 9.943736e-01 0.002 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 9.943736e-01 0.002 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 9.943736e-01 0.002 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 9.943736e-01 0.002 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.950423e-01 0.002 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.950423e-01 0.002 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.950423e-01 0.002 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.951167e-01 0.002 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.954238e-01 0.002 0 0
Innate Immune System R-HSA-168249 9.955622e-01 0.002 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.956315e-01 0.002 0 0
HS-GAG biosynthesis R-HSA-2022928 9.956315e-01 0.002 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.956330e-01 0.002 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 9.956330e-01 0.002 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 9.956330e-01 0.002 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.960957e-01 0.002 0 0
Ubiquinol biosynthesis R-HSA-2142789 9.961507e-01 0.002 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.961507e-01 0.002 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.961507e-01 0.002 0 0
Metabolism of folate and pterines R-HSA-196757 9.961507e-01 0.002 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.966082e-01 0.001 0 0
Elastic fibre formation R-HSA-1566948 9.966082e-01 0.001 0 0
Interferon alpha/beta signaling R-HSA-909733 9.967534e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.972042e-01 0.001 0 0
Metabolism of cofactors R-HSA-8978934 9.972042e-01 0.001 0 0
Peptide hormone metabolism R-HSA-2980736 9.972567e-01 0.001 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.972899e-01 0.001 0 0
N-glycan antennae elongation in the medial/trans-Golgi R-HSA-975576 9.973666e-01 0.001 0 0
Tryptophan catabolism R-HSA-71240 9.973666e-01 0.001 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.973666e-01 0.001 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.974590e-01 0.001 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.975367e-01 0.001 0 0
G alpha (s) signalling events R-HSA-418555 9.975508e-01 0.001 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.976797e-01 0.001 0 0
Pyruvate metabolism R-HSA-70268 9.979454e-01 0.001 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.979551e-01 0.001 0 0
Triglyceride metabolism R-HSA-8979227 9.980147e-01 0.001 0 0
Translation R-HSA-72766 9.981045e-01 0.001 0 0
Protein ubiquitination R-HSA-8852135 9.981585e-01 0.001 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 9.981986e-01 0.001 0 0
Depyrimidination R-HSA-73928 9.981986e-01 0.001 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.982275e-01 0.001 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.983540e-01 0.001 0 0
Interleukin-1 signaling R-HSA-9020702 9.984059e-01 0.001 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.984128e-01 0.001 0 0
Endogenous sterols R-HSA-211976 9.984178e-01 0.001 0 0
Collagen degradation R-HSA-1442490 9.984178e-01 0.001 0 0
Downstream TCR signaling R-HSA-202424 9.984718e-01 0.001 0 0
Neurotransmitter release cycle R-HSA-112310 9.984718e-01 0.001 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.986015e-01 0.001 0 0
Methylation R-HSA-156581 9.986015e-01 0.001 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.986015e-01 0.001 0 0
Disease R-HSA-1643685 9.986198e-01 0.001 0 0
mitochondrial fatty acid beta-oxidation of saturated fatty acids R-HSA-77286 9.987678e-01 0.001 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 9.987678e-01 0.001 0 0
The canonical retinoid cycle in rods (twilight vision) R-HSA-2453902 9.987678e-01 0.001 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.987918e-01 0.001 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.988659e-01 0.000 0 0
Xenobiotics R-HSA-211981 9.988759e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.989352e-01 0.000 0 0
Synthesis of PC R-HSA-1483191 9.990435e-01 0.000 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.990435e-01 0.000 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.991057e-01 0.000 0 0
Metal ion SLC transporters R-HSA-425410 9.991572e-01 0.000 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.993458e-01 0.000 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.994236e-01 0.000 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.994236e-01 0.000 0 0
Complex IV assembly R-HSA-9864848 9.994236e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.994350e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.994829e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.994965e-01 0.000 0 0
ECM proteoglycans R-HSA-3000178 9.994965e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.994965e-01 0.000 0 0
ABC-family proteins mediated transport R-HSA-382556 9.995425e-01 0.000 0 0
Purine catabolism R-HSA-74259 9.995513e-01 0.000 0 0
Post-translational protein modification R-HSA-597592 9.995644e-01 0.000 0 0
Aspirin ADME R-HSA-9749641 9.996002e-01 0.000 0 0
Glucuronidation R-HSA-156588 9.996058e-01 0.000 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.996527e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.996941e-01 0.000 0 0
Metabolism of nucleotides R-HSA-15869 9.997743e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.997760e-01 0.000 0 0
Sialic acid metabolism R-HSA-4085001 9.997908e-01 0.000 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.997908e-01 0.000 0 0
Glutathione conjugation R-HSA-156590 9.998157e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.998279e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.998420e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.998527e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.998740e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.998890e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.998994e-01 0.000 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.999216e-01 0.000 0 0
Nicotinate metabolism R-HSA-196807 9.999241e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.999241e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.999292e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.999331e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999510e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.999514e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999641e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.999692e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.999728e-01 0.000 0 0
Interleukin-10 signaling R-HSA-6783783 9.999812e-01 0.000 0 0
ABC transporter disorders R-HSA-5619084 9.999812e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.999857e-01 0.000 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.999871e-01 0.000 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.999900e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999912e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.999920e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999941e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999945e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999953e-01 0.000 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.999983e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999987e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999990e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999994e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999995e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999995e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.999996e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999996e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999997e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999998e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999998e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999998e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999998e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.999999e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.999999e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999999e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 1.000000e+00 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 1.000000e+00 0.000 0 0
Regulation of Complement cascade R-HSA-977606 1.000000e+00 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Mitochondrial translation R-HSA-5368287 1.000000e+00 0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 1.000000e+00 0.000 0 0
Complement cascade R-HSA-166658 1.000000e+00 0.000 0 0
Metabolism of steroids R-HSA-8957322 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 -0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 -0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Cell Cycle, Mitotic R-HSA-69278 1.110223e-16 15.955 1 0
M Phase R-HSA-68886 1.110223e-16 15.955 1 0
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 1 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Metabolism of RNA R-HSA-8953854 1.110223e-15 14.955 0 0
Cellular response to heat stress R-HSA-3371556 4.718448e-14 13.326 0 0
Cell-Cell communication R-HSA-1500931 2.128298e-13 12.672 0 0
Mitotic Prophase R-HSA-68875 1.567413e-12 11.805 1 0
Mitotic Anaphase R-HSA-68882 4.297229e-12 11.367 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 5.153766e-12 11.288 0 0
Axon guidance R-HSA-422475 8.262613e-12 11.083 0 0
Cell junction organization R-HSA-446728 1.146727e-11 10.941 0 0
Nervous system development R-HSA-9675108 1.340517e-11 10.873 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.259405e-10 9.900 0 0
Apoptotic execution phase R-HSA-75153 2.494531e-10 9.603 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.534975e-10 9.452 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 4.353372e-10 9.361 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 4.794900e-10 9.319 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.766481e-10 9.239 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.766481e-10 9.239 0 0
Mitotic Prometaphase R-HSA-68877 1.038546e-09 8.984 1 0
Membrane Trafficking R-HSA-199991 1.146207e-09 8.941 0 0
Apoptosis R-HSA-109581 1.274003e-09 8.895 0 0
Adherens junctions interactions R-HSA-418990 1.744832e-09 8.758 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.193775e-09 8.659 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.193775e-09 8.659 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.155388e-09 8.666 0 0
Nuclear Envelope Breakdown R-HSA-2980766 2.965066e-09 8.528 1 0
Cell-cell junction organization R-HSA-421270 3.008038e-09 8.522 0 0
Programmed Cell Death R-HSA-5357801 3.400453e-09 8.468 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 4.320522e-09 8.364 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 6.911349e-09 8.160 0 0
HSF1-dependent transactivation R-HSA-3371571 6.814943e-09 8.167 0 0
Attenuation phase R-HSA-3371568 7.583034e-09 8.120 0 0
Cell Cycle Checkpoints R-HSA-69620 7.921976e-09 8.101 0 0
Signal Transduction R-HSA-162582 8.058466e-09 8.094 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 8.609169e-09 8.065 0 0
Ub-specific processing proteases R-HSA-5689880 1.028414e-08 7.988 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.056459e-08 7.976 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.228058e-08 7.911 0 0
Separation of Sister Chromatids R-HSA-2467813 1.265027e-08 7.898 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.355697e-08 7.868 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.603328e-08 7.795 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.603328e-08 7.795 0 0
Translation initiation complex formation R-HSA-72649 1.809151e-08 7.743 0 0
Signaling by RAS mutants R-HSA-6802949 2.176733e-08 7.662 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.176733e-08 7.662 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.176733e-08 7.662 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.176733e-08 7.662 0 0
HDACs deacetylate histones R-HSA-3214815 2.470709e-08 7.607 0 0
G2/M Transition R-HSA-69275 3.272152e-08 7.485 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 3.219046e-08 7.492 0 0
Eukaryotic Translation Elongation R-HSA-156842 3.450144e-08 7.462 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.179279e-08 7.379 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.431869e-08 7.353 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 4.760430e-08 7.322 0 0
Gene Silencing by RNA R-HSA-211000 4.974245e-08 7.303 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 6.103051e-08 7.214 0 0
Influenza Infection R-HSA-168255 6.597674e-08 7.181 0 0
Cellular Senescence R-HSA-2559583 7.676020e-08 7.115 0 0
Signaling by ERBB2 R-HSA-1227986 1.068328e-07 6.971 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.187960e-07 6.925 0 0
Meiosis R-HSA-1500620 1.356604e-07 6.868 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.409472e-07 6.851 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.526985e-07 6.816 0 0
G2/M Checkpoints R-HSA-69481 1.855588e-07 6.732 0 0
Meiotic synapsis R-HSA-1221632 1.958679e-07 6.708 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.958679e-07 6.708 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.474196e-07 6.607 0 0
Host Interactions of HIV factors R-HSA-162909 2.422911e-07 6.616 0 0
Nucleosome assembly R-HSA-774815 2.579569e-07 6.588 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 2.579569e-07 6.588 0 0
Post NMDA receptor activation events R-HSA-438064 2.651618e-07 6.576 0 0
Signaling by RAF1 mutants R-HSA-9656223 2.878318e-07 6.541 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 3.310794e-07 6.480 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.310794e-07 6.480 0 0
Selective autophagy R-HSA-9663891 3.292911e-07 6.482 0 0
Viral Infection Pathways R-HSA-9824446 3.351519e-07 6.475 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 3.360182e-07 6.474 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 4.014103e-07 6.396 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.242490e-07 6.372 0 0
mRNA Splicing R-HSA-72172 4.830277e-07 6.316 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.880312e-07 6.312 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 5.571431e-07 6.254 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 5.309406e-07 6.275 0 0
Deubiquitination R-HSA-5688426 5.703093e-07 6.244 0 0
Regulation of CDH1 Function R-HSA-9764561 5.935275e-07 6.227 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 6.083651e-07 6.216 0 0
HSF1 activation R-HSA-3371511 6.659559e-07 6.177 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 6.328661e-07 6.199 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.703194e-07 6.174 0 0
HIV Infection R-HSA-162906 8.522196e-07 6.069 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 9.298688e-07 6.032 0 0
Peptide chain elongation R-HSA-156902 9.748337e-07 6.011 0 0
EPH-Ephrin signaling R-HSA-2682334 9.271085e-07 6.033 0 0
SARS-CoV-2-host interactions R-HSA-9705683 9.615587e-07 6.017 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.129988e-06 5.947 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 1.320572e-06 5.879 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.283660e-06 5.892 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.322768e-06 5.879 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.283660e-06 5.892 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.428646e-06 5.845 0 0
Ribosome-associated quality control R-HSA-9948299 1.572955e-06 5.803 0 0
HATs acetylate histones R-HSA-3214847 1.546972e-06 5.811 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.566381e-06 5.805 1 1
Interleukin-12 signaling R-HSA-9020591 1.649743e-06 5.783 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.973199e-06 5.705 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 2.157717e-06 5.666 0 0
Aggrephagy R-HSA-9646399 2.391126e-06 5.621 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 2.630923e-06 5.580 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 2.630923e-06 5.580 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.790632e-06 5.554 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 2.674156e-06 5.573 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 2.905136e-06 5.537 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 2.964355e-06 5.528 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 3.227873e-06 5.491 0 0
G2/M DNA damage checkpoint R-HSA-69473 3.233233e-06 5.490 0 0
Oncogenic MAPK signaling R-HSA-6802957 3.615365e-06 5.442 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 3.792011e-06 5.421 0 0
Signaling by ROBO receptors R-HSA-376176 3.836821e-06 5.416 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 4.123228e-06 5.385 0 0
MAP2K and MAPK activation R-HSA-5674135 4.296989e-06 5.367 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 4.557558e-06 5.341 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 4.574780e-06 5.340 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 4.944430e-06 5.306 0 0
Meiotic recombination R-HSA-912446 5.060535e-06 5.296 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.456630e-06 5.263 0 0
Macroautophagy R-HSA-1632852 5.813948e-06 5.236 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 5.978283e-06 5.223 0 0
Estrogen-dependent gene expression R-HSA-9018519 6.640893e-06 5.178 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 6.910126e-06 5.161 0 0
L1CAM interactions R-HSA-373760 7.001182e-06 5.155 0 0
RNA Polymerase I Transcription R-HSA-73864 7.360912e-06 5.133 0 0
HCMV Early Events R-HSA-9609690 7.419700e-06 5.130 0 0
Diseases of programmed cell death R-HSA-9645723 7.751113e-06 5.111 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 7.758964e-06 5.110 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 7.807291e-06 5.107 1 1
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 8.862111e-06 5.052 0 0
Signaling by Hippo R-HSA-2028269 9.657488e-06 5.015 0 0
Autophagy R-HSA-9612973 9.963448e-06 5.002 0 0
Interferon Signaling R-HSA-913531 1.013306e-05 4.994 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.034715e-05 4.985 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.035544e-05 4.985 0 0
HIV Life Cycle R-HSA-162587 1.134671e-05 4.945 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.179913e-05 4.928 0 0
Vesicle-mediated transport R-HSA-5653656 1.321050e-05 4.879 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.310882e-05 4.882 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.257209e-05 4.901 0 0
DNA methylation R-HSA-5334118 1.363377e-05 4.865 0 0
Neutrophil degranulation R-HSA-6798695 1.380823e-05 4.860 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.411134e-05 4.850 0 0
Chaperone Mediated Autophagy R-HSA-9613829 1.489456e-05 4.827 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.500087e-05 4.824 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 1.696714e-05 4.770 0 0
Interleukin-12 family signaling R-HSA-447115 1.742529e-05 4.759 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.791456e-05 4.747 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 2.023940e-05 4.694 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.023940e-05 4.694 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 2.107457e-05 4.676 0 0
ESR-mediated signaling R-HSA-8939211 2.169551e-05 4.664 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 2.436600e-05 4.613 0 0
Co-inhibition by PD-1 R-HSA-389948 2.408827e-05 4.618 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 2.494242e-05 4.603 0 0
Signaling by PTK6 R-HSA-8848021 2.494242e-05 4.603 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.532707e-05 4.596 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 2.561756e-05 4.591 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.690114e-05 4.570 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 2.904198e-05 4.537 0 0
Packaging Of Telomere Ends R-HSA-171306 2.904198e-05 4.537 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.983281e-05 4.525 0 0
Signaling by VEGF R-HSA-194138 3.058793e-05 4.514 0 0
TCF dependent signaling in response to WNT R-HSA-201681 3.075062e-05 4.512 0 0
Chromatin modifying enzymes R-HSA-3247509 3.106242e-05 4.508 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.171585e-05 4.499 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.171585e-05 4.499 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 3.306350e-05 4.481 0 0
Eukaryotic Translation Termination R-HSA-72764 3.646847e-05 4.438 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 4.085611e-05 4.389 0 0
PRC2 methylates histones and DNA R-HSA-212300 3.850867e-05 4.414 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 3.848418e-05 4.415 0 0
Selenocysteine synthesis R-HSA-2408557 3.792391e-05 4.421 0 0
COPI-mediated anterograde transport R-HSA-6807878 4.275572e-05 4.369 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.607852e-05 4.337 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 4.607852e-05 4.337 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 4.804879e-05 4.318 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 4.804879e-05 4.318 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 5.025601e-05 4.299 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 5.253322e-05 4.280 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 5.377095e-05 4.269 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 5.987139e-05 4.223 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 6.505058e-05 4.187 0 0
Depurination R-HSA-73927 6.505058e-05 4.187 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 6.659588e-05 4.177 0 0
Chromatin organization R-HSA-4839726 6.889312e-05 4.162 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 7.049775e-05 4.152 0 0
RAF activation R-HSA-5673000 7.969080e-05 4.099 0 0
Nuclear import of Rev protein R-HSA-180746 7.969080e-05 4.099 0 0
Signaling by WNT R-HSA-195721 7.702331e-05 4.113 0 0
Regulation of TP53 Activity R-HSA-5633007 7.466874e-05 4.127 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 7.969080e-05 4.099 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 7.986691e-05 4.098 0 0
Nef and signal transduction R-HSA-164944 8.133858e-05 4.090 0 0
Late Phase of HIV Life Cycle R-HSA-162599 8.313771e-05 4.080 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 8.343408e-05 4.079 0 0
Metalloprotease DUBs R-HSA-5689901 8.461191e-05 4.073 0 0
Protein ubiquitination R-HSA-8852135 8.726538e-05 4.059 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 8.780541e-05 4.056 0 0
SARS-CoV-2 Infection R-HSA-9694516 9.176846e-05 4.037 0 0
Processing of DNA double-strand break ends R-HSA-5693607 9.323521e-05 4.030 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 9.338265e-05 4.030 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.599628e-05 4.018 0 0
Signaling by NOTCH R-HSA-157118 1.038022e-04 3.984 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.063053e-04 3.973 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.064880e-04 3.973 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 1.099588e-04 3.959 0 0
SARS-CoV Infections R-HSA-9679506 1.202856e-04 3.920 0 0
Viral mRNA Translation R-HSA-192823 1.219421e-04 3.914 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.281702e-04 3.892 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.320696e-04 3.879 0 0
MAPK family signaling cascades R-HSA-5683057 1.342766e-04 3.872 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.347640e-04 3.870 0 0
FLT3 Signaling R-HSA-9607240 1.347640e-04 3.870 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.546258e-04 3.811 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.522947e-04 3.817 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.519530e-04 3.818 0 0
Reproduction R-HSA-1474165 1.478597e-04 3.830 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.645200e-04 3.784 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.647796e-04 3.783 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.697549e-04 3.770 0 0
Cleavage of the damaged purine R-HSA-110331 1.697549e-04 3.770 0 0
Muscle contraction R-HSA-397014 1.747305e-04 3.758 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.794648e-04 3.746 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.795682e-04 3.746 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.921364e-04 3.716 0 0
Semaphorin interactions R-HSA-373755 1.977271e-04 3.704 0 0
Recycling pathway of L1 R-HSA-437239 2.033603e-04 3.692 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 2.105811e-04 3.677 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 2.120826e-04 3.673 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.252080e-04 3.647 0 0
Long-term potentiation R-HSA-9620244 2.409347e-04 3.618 0 0
HCMV Infection R-HSA-9609646 2.487862e-04 3.604 0 0
Metabolism of non-coding RNA R-HSA-194441 2.596084e-04 3.586 0 0
snRNP Assembly R-HSA-191859 2.596084e-04 3.586 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.621207e-04 3.581 0 0
Defective pyroptosis R-HSA-9710421 2.623772e-04 3.581 0 0
Homology Directed Repair R-HSA-5693538 2.631756e-04 3.580 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 2.702665e-04 3.568 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.819918e-04 3.550 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.819918e-04 3.550 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.890070e-04 3.539 0 0
Signaling by EGFR in Cancer R-HSA-1643713 3.192871e-04 3.496 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 3.386860e-04 3.470 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 3.386860e-04 3.470 0 0
Degradation of CDH1 R-HSA-9766229 3.046675e-04 3.516 0 0
AURKA Activation by TPX2 R-HSA-8854518 3.329123e-04 3.478 0 0
Cell-extracellular matrix interactions R-HSA-446353 3.403587e-04 3.468 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 3.321567e-04 3.479 0 0
Transport of connexons to the plasma membrane R-HSA-190872 3.184392e-04 3.497 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 3.403587e-04 3.468 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 3.373893e-04 3.472 0 0
Kinesins R-HSA-983189 3.106537e-04 3.508 0 0
rRNA processing R-HSA-72312 3.105785e-04 3.508 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 3.403587e-04 3.468 0 0
DNA Double Strand Break Response R-HSA-5693606 3.931503e-04 3.405 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 4.183594e-04 3.378 0 0
Glycolysis R-HSA-70171 4.211060e-04 3.376 0 0
Cellular response to starvation R-HSA-9711097 4.844850e-04 3.315 0 0
PKR-mediated signaling R-HSA-9833482 4.885422e-04 3.311 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 4.921743e-04 3.308 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 4.921743e-04 3.308 0 0
Gene expression (Transcription) R-HSA-74160 5.038712e-04 3.298 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 5.056556e-04 3.296 0 0
Negative regulation of MAPK pathway R-HSA-5675221 5.154292e-04 3.288 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 5.197237e-04 3.284 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 5.197237e-04 3.284 0 0
mRNA 3'-end processing R-HSA-72187 5.376357e-04 3.270 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.499606e-04 3.260 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 5.804836e-04 3.236 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 6.026655e-04 3.220 0 0
Nephrin family interactions R-HSA-373753 6.026655e-04 3.220 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 6.232975e-04 3.205 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 6.311091e-04 3.200 0 0
Depyrimidination R-HSA-73928 6.311091e-04 3.200 0 0
Smooth Muscle Contraction R-HSA-445355 6.435199e-04 3.191 0 0
S Phase R-HSA-69242 6.676298e-04 3.175 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 6.683838e-04 3.175 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 6.683838e-04 3.175 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 6.899775e-04 3.161 0 0
Striated Muscle Contraction R-HSA-390522 6.918043e-04 3.160 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 6.918043e-04 3.160 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 6.948609e-04 3.158 0 0
Josephin domain DUBs R-HSA-5689877 7.301001e-04 3.137 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 7.301001e-04 3.137 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 7.461625e-04 3.127 0 0
Chromosome Maintenance R-HSA-73886 7.863647e-04 3.104 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 8.074946e-04 3.093 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 8.824509e-04 3.054 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 9.529472e-04 3.021 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 8.582782e-04 3.066 0 0
Epigenetic regulation of gene expression R-HSA-212165 8.500888e-04 3.071 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 8.824509e-04 3.054 0 0
Cellular response to chemical stress R-HSA-9711123 1.012060e-03 2.995 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.326347e-04 3.030 0 0
Gap junction trafficking and regulation R-HSA-157858 8.485823e-04 3.071 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 8.649254e-04 3.063 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 9.876961e-04 3.005 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.070142e-03 2.971 0 0
Signaling by EGFR R-HSA-177929 1.074691e-03 2.969 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.079612e-03 2.967 0 0
DNA Replication R-HSA-69306 1.089536e-03 2.963 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.115993e-03 2.952 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 1.116525e-03 2.952 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.127968e-03 2.948 0 0
Signaling by ALK in cancer R-HSA-9700206 1.127968e-03 2.948 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.129625e-03 2.947 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.129625e-03 2.947 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.129625e-03 2.947 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.129625e-03 2.947 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 1.230659e-03 2.910 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.289280e-03 2.890 0 0
Ephrin signaling R-HSA-3928664 1.289280e-03 2.890 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.289280e-03 2.890 0 0
Amyloid fiber formation R-HSA-977225 1.308477e-03 2.883 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 1.339898e-03 2.873 0 0
Protein folding R-HSA-391251 1.420399e-03 2.848 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.461577e-03 2.835 0 0
Infectious disease R-HSA-5663205 1.469420e-03 2.833 0 0
p38MAPK events R-HSA-171007 1.500255e-03 2.824 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.500255e-03 2.824 0 0
Clathrin-mediated endocytosis R-HSA-8856828 1.505367e-03 2.822 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 1.523021e-03 2.817 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.575055e-03 2.803 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.596197e-03 2.797 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.602446e-03 2.795 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.616191e-03 2.792 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.616191e-03 2.792 0 0
Translation R-HSA-72766 1.640904e-03 2.785 0 0
Regulation of signaling by CBL R-HSA-912631 1.716935e-03 2.765 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.944457e-03 2.711 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.948528e-03 2.710 0 0
Immune System R-HSA-168256 1.965813e-03 2.706 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.970074e-03 2.706 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.182693e-03 2.661 0 0
Late endosomal microautophagy R-HSA-9615710 2.228962e-03 2.652 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.251276e-03 2.648 0 0
Negative regulation of MET activity R-HSA-6807004 2.251276e-03 2.648 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 2.285818e-03 2.641 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.291371e-03 2.640 0 0
Neurodegenerative Diseases R-HSA-8863678 2.291371e-03 2.640 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.301796e-03 2.638 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.478112e-03 2.606 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.478112e-03 2.606 0 0
Gap junction trafficking R-HSA-190828 2.514464e-03 2.600 0 0
Regulation of RAS by GAPs R-HSA-5658442 2.622432e-03 2.581 0 0
tRNA processing in the nucleus R-HSA-6784531 2.692525e-03 2.570 0 0
Cilium Assembly R-HSA-5617833 2.694853e-03 2.569 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.864637e-03 2.543 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.886022e-03 2.540 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.611040e-03 2.442 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 3.611040e-03 2.442 0 0
Centrosome maturation R-HSA-380287 2.988279e-03 2.525 0 0
UCH proteinases R-HSA-5689603 3.390976e-03 2.470 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.971983e-03 2.527 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 2.978992e-03 2.526 0 0
Signalling to ERKs R-HSA-187687 3.103149e-03 2.508 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.344896e-03 2.476 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.642301e-03 2.439 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.642301e-03 2.439 0 0
Folding of actin by CCT/TriC R-HSA-390450 3.661538e-03 2.436 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 3.661538e-03 2.436 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.730006e-03 2.428 0 0
FLT3 signaling in disease R-HSA-9682385 3.730006e-03 2.428 0 0
Glucose metabolism R-HSA-70326 4.000783e-03 2.398 0 0
Developmental Biology R-HSA-1266738 4.071381e-03 2.390 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.427797e-03 2.354 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 4.442084e-03 2.352 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 4.442084e-03 2.352 0 0
Regulation of KIT signaling R-HSA-1433559 4.450654e-03 2.352 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 4.495635e-03 2.347 0 0
mTORC1-mediated signalling R-HSA-166208 4.678521e-03 2.330 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 4.678521e-03 2.330 0 0
Signaling by KIT in disease R-HSA-9669938 4.678521e-03 2.330 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 4.957416e-03 2.305 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.957416e-03 2.305 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 4.957416e-03 2.305 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 4.957416e-03 2.305 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 4.957416e-03 2.305 0 0
DNA Repair R-HSA-73894 4.985357e-03 2.302 0 0
Selenoamino acid metabolism R-HSA-2408522 5.099328e-03 2.292 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 5.106673e-03 2.292 0 0
HCMV Late Events R-HSA-9610379 5.109299e-03 2.292 0 0
PECAM1 interactions R-HSA-210990 5.210195e-03 2.283 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 5.435046e-03 2.265 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 5.532842e-03 2.257 0 0
Regulation of PTEN localization R-HSA-8948747 5.590980e-03 2.253 0 0
SOS-mediated signalling R-HSA-112412 5.590980e-03 2.253 0 0
Signaling by ERBB4 R-HSA-1236394 5.733601e-03 2.242 0 0
Telomere Maintenance R-HSA-157579 5.747106e-03 2.241 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 5.747106e-03 2.241 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.918175e-03 2.228 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 5.918175e-03 2.228 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 5.918175e-03 2.228 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.918175e-03 2.228 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 5.918175e-03 2.228 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.918175e-03 2.228 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 5.941252e-03 2.226 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 5.947239e-03 2.226 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.043402e-03 2.219 0 0
Ion homeostasis R-HSA-5578775 6.312168e-03 2.200 0 0
RMTs methylate histone arginines R-HSA-3214858 6.379241e-03 2.195 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 7.016488e-03 2.154 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 7.072381e-03 2.150 0 0
Mitophagy R-HSA-5205647 7.072381e-03 2.150 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 7.191465e-03 2.143 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 7.191465e-03 2.143 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 7.325328e-03 2.135 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 7.363672e-03 2.133 0 0
RNA Polymerase II Transcription R-HSA-73857 7.398535e-03 2.131 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 7.593233e-03 2.120 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 7.593233e-03 2.120 0 0
Signal transduction by L1 R-HSA-445144 7.621163e-03 2.118 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 7.719785e-03 2.112 0 0
Negative regulation of FLT3 R-HSA-9706369 7.719785e-03 2.112 0 0
Hedgehog 'off' state R-HSA-5610787 7.745456e-03 2.111 0 0
Activation of BH3-only proteins R-HSA-114452 7.934973e-03 2.100 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.044560e-02 1.981 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.044560e-02 1.981 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 8.170355e-03 2.088 0 0
Formation of annular gap junctions R-HSA-196025 8.234627e-03 2.084 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 9.896936e-03 2.004 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 1.061437e-02 1.974 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.477182e-03 2.023 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 8.557361e-03 2.068 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 8.430673e-03 2.074 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 9.626264e-03 2.017 0 0
Regulation of TNFR1 signaling R-HSA-5357905 8.557361e-03 2.068 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 8.170355e-03 2.088 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 9.666675e-03 2.015 0 0
Regulation of TP53 Degradation R-HSA-6804757 9.833436e-03 2.007 0 0
Regulation of Apoptosis R-HSA-169911 8.364948e-03 2.078 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.531093e-03 2.021 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 9.477182e-03 2.023 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.845773e-03 2.007 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 8.774764e-03 2.057 0 0
Platelet degranulation R-HSA-114608 1.057882e-02 1.976 0 0
Signalling to RAS R-HSA-167044 9.490155e-03 2.023 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 9.477182e-03 2.023 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.531686e-03 2.069 0 0
Hemostasis R-HSA-109582 9.447957e-03 2.025 0 0
Base Excision Repair R-HSA-73884 8.871034e-03 2.052 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 8.234627e-03 2.084 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.050309e-02 1.979 0 0
Switching of origins to a post-replicative state R-HSA-69052 1.068635e-02 1.971 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 1.095116e-02 1.961 0 0
Signaling by MET R-HSA-6806834 1.119432e-02 1.951 0 0
TCR signaling R-HSA-202403 1.138073e-02 1.944 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.148064e-02 1.940 0 0
MTOR signalling R-HSA-165159 1.148064e-02 1.940 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.149257e-02 1.940 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.149257e-02 1.940 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 1.163874e-02 1.934 0 0
Gap junction degradation R-HSA-190873 1.163874e-02 1.934 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.163874e-02 1.934 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 1.168043e-02 1.933 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.168043e-02 1.933 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.187705e-02 1.925 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.230800e-02 1.910 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.230800e-02 1.910 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.241431e-02 1.906 0 0
Signaling by NOTCH3 R-HSA-9012852 1.241431e-02 1.906 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.246619e-02 1.904 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.272924e-02 1.895 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.272924e-02 1.895 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.272924e-02 1.895 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 1.279112e-02 1.893 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 1.279112e-02 1.893 0 0
Maturation of protein E R-HSA-9694493 1.279112e-02 1.893 0 0
Maturation of protein E R-HSA-9683683 1.279112e-02 1.893 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.320763e-02 1.879 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 1.325119e-02 1.878 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.334924e-02 1.875 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.335722e-02 1.874 0 0
TNF signaling R-HSA-75893 1.402476e-02 1.853 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.422177e-02 1.847 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 1.435260e-02 1.843 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.461850e-02 1.835 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 1.512622e-02 1.820 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.544226e-02 1.811 0 0
Stabilization of p53 R-HSA-69541 1.544226e-02 1.811 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 1.554072e-02 1.809 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.589149e-02 1.799 0 0
Pexophagy R-HSA-9664873 1.589149e-02 1.799 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.589149e-02 1.799 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 1.633371e-02 1.787 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 1.633371e-02 1.787 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.714327e-02 1.766 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 1.724882e-02 1.763 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 1.724882e-02 1.763 0 0
Regulation of mitotic cell cycle R-HSA-453276 1.743405e-02 1.759 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 1.743405e-02 1.759 0 0
Signaling by Interleukins R-HSA-449147 1.796789e-02 1.746 0 0
Gap junction assembly R-HSA-190861 1.801680e-02 1.744 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.869639e-02 1.728 0 0
Orc1 removal from chromatin R-HSA-68949 1.869639e-02 1.728 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 1.880966e-02 1.726 1 1
Translesion Synthesis by POLH R-HSA-110320 1.908526e-02 1.719 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 1.958778e-02 1.708 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 2.033258e-02 1.692 0 0
Erythropoietin activates RAS R-HSA-9027284 2.063386e-02 1.685 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 2.063386e-02 1.685 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 2.083453e-02 1.681 0 0
Regulation of PTEN stability and activity R-HSA-8948751 2.102194e-02 1.677 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.102194e-02 1.677 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 2.102194e-02 1.677 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 2.107014e-02 1.676 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 2.121914e-02 1.673 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 2.121914e-02 1.673 0 0
Signaling by FGFR2 R-HSA-5654738 2.178210e-02 1.662 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 2.212177e-02 1.655 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 2.212177e-02 1.655 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 2.212177e-02 1.655 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 2.212177e-02 1.655 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 2.212177e-02 1.655 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 2.215525e-02 1.655 0 0
Signaling by NOTCH4 R-HSA-9013694 2.351947e-02 1.629 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.396029e-02 1.621 0 0
EGFR downregulation R-HSA-182971 2.439086e-02 1.613 0 0
Intraflagellar transport R-HSA-5620924 2.496310e-02 1.603 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.631158e-02 1.580 0 0
Recycling of eIF2:GDP R-HSA-72731 2.632925e-02 1.580 0 0
Integration of provirus R-HSA-162592 2.723933e-02 1.565 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 2.723933e-02 1.565 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 2.741050e-02 1.562 0 0
Degradation of DVL R-HSA-4641258 2.741050e-02 1.562 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.779729e-02 1.556 0 0
Basigin interactions R-HSA-210991 2.779729e-02 1.556 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 2.802289e-02 1.552 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 2.802289e-02 1.552 0 0
Myogenesis R-HSA-525793 2.846169e-02 1.546 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 3.000461e-02 1.523 0 0
Regulation of gap junction activity R-HSA-191650 3.000461e-02 1.523 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 3.000461e-02 1.523 0 0
Type I hemidesmosome assembly R-HSA-446107 3.541646e-02 1.451 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.444999e-02 1.463 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.302670e-02 1.481 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 3.302670e-02 1.481 0 0
Notch-HLH transcription pathway R-HSA-350054 3.887351e-02 1.410 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.708084e-02 1.431 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 3.708084e-02 1.431 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.534566e-02 1.452 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 3.741303e-02 1.427 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.929557e-02 1.533 0 0
PTEN Regulation R-HSA-6807070 2.940985e-02 1.532 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 3.139982e-02 1.503 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 3.139982e-02 1.503 0 0
RAS processing R-HSA-9648002 3.534566e-02 1.452 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 3.696073e-02 1.432 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 3.075991e-02 1.512 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 3.444999e-02 1.463 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 3.000461e-02 1.523 0 0
VLDLR internalisation and degradation R-HSA-8866427 3.444999e-02 1.463 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 3.444999e-02 1.463 0 0
IRAK1 recruits IKK complex R-HSA-937039 3.444999e-02 1.463 0 0
GRB2 events in EGFR signaling R-HSA-179812 3.444999e-02 1.463 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 3.887351e-02 1.410 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 4.273868e-02 1.369 0 0
Signaling by SCF-KIT R-HSA-1433557 2.968232e-02 1.528 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 3.302670e-02 1.481 0 0
Generic Transcription Pathway R-HSA-212436 3.435020e-02 1.464 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 3.018400e-02 1.520 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 3.541646e-02 1.451 0 0
Activation of RAS in B cells R-HSA-1169092 3.541646e-02 1.451 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 3.985871e-02 1.399 0 0
G1 Phase R-HSA-69236 3.338973e-02 1.476 0 0
Cyclin D associated events in G1 R-HSA-69231 3.338973e-02 1.476 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 3.566678e-02 1.448 0 0
Signaling by TGFB family members R-HSA-9006936 2.896852e-02 1.538 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 4.273868e-02 1.369 0 0
Vpu mediated degradation of CD4 R-HSA-180534 3.708084e-02 1.431 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 4.215836e-02 1.375 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 4.215836e-02 1.375 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 2.929557e-02 1.533 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.018400e-02 1.520 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 4.215836e-02 1.375 0 0
Signaling by FGFR4 R-HSA-5654743 2.968232e-02 1.528 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 3.882243e-02 1.411 0 0
Signaling by FGFR3 R-HSA-5654741 3.741303e-02 1.427 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.929557e-02 1.533 0 0
Signaling by PDGFR in disease R-HSA-9671555 3.302670e-02 1.481 0 0
p75NTR recruits signalling complexes R-HSA-209543 3.444999e-02 1.463 0 0
XBP1(S) activates chaperone genes R-HSA-381038 4.002237e-02 1.398 0 0
IRE1alpha activates chaperones R-HSA-381070 3.660911e-02 1.436 0 0
Modulation by Mtb of host immune system R-HSA-9637628 3.541646e-02 1.451 0 0
G1/S Transition R-HSA-69206 4.392106e-02 1.357 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 4.392106e-02 1.357 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 4.392106e-02 1.357 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 4.392106e-02 1.357 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 4.398929e-02 1.357 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 4.398929e-02 1.357 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 4.398929e-02 1.357 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 4.410834e-02 1.355 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 4.410834e-02 1.355 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.410834e-02 1.355 0 0
Signaling by Hedgehog R-HSA-5358351 4.411382e-02 1.355 0 0
Defective Base Excision Repair Associated with OGG1 R-HSA-9656249 4.442236e-02 1.352 0 0
Manipulation of host energy metabolism R-HSA-9636667 4.442236e-02 1.352 0 0
Breakdown of the nuclear lamina R-HSA-352238 4.442236e-02 1.352 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 4.475216e-02 1.349 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 4.475216e-02 1.349 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 4.475216e-02 1.349 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 4.528875e-02 1.344 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 4.610273e-02 1.336 0 0
Lipophagy R-HSA-9613354 4.610273e-02 1.336 0 0
ALK mutants bind TKIs R-HSA-9700645 4.610273e-02 1.336 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 4.610273e-02 1.336 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 4.610273e-02 1.336 0 0
Cellular response to mitochondrial stress R-HSA-9840373 4.610273e-02 1.336 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 4.630399e-02 1.334 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 4.768378e-02 1.322 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 4.768378e-02 1.322 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 4.768378e-02 1.322 0 0
Oncogene Induced Senescence R-HSA-2559585 4.768378e-02 1.322 0 0
Regulated Necrosis R-HSA-5218859 4.807831e-02 1.318 0 0
Interleukin-1 signaling R-HSA-9020702 4.855364e-02 1.314 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 5.003693e-02 1.301 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 5.003693e-02 1.301 0 0
DAP12 signaling R-HSA-2424491 5.037456e-02 1.298 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 5.037456e-02 1.298 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 5.212753e-02 1.283 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 5.212753e-02 1.283 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.212753e-02 1.283 0 0
G alpha (z) signalling events R-HSA-418597 5.225502e-02 1.282 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 5.249969e-02 1.280 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 5.346552e-02 1.272 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 5.346552e-02 1.272 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 5.572249e-02 1.254 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.572249e-02 1.254 0 0
Interferon alpha/beta signaling R-HSA-909733 5.629257e-02 1.250 0 0
Trafficking of AMPA receptors R-HSA-399719 5.718874e-02 1.243 0 0
Signaling by FGFR1 R-HSA-5654736 5.735598e-02 1.241 0 0
MHC class II antigen presentation R-HSA-2132295 5.808336e-02 1.236 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 5.838704e-02 1.234 0 0
2-LTR circle formation R-HSA-164843 5.838704e-02 1.234 0 0
Regulation of CDH11 function R-HSA-9762292 5.838704e-02 1.234 0 0
Response of endothelial cells to shear stress R-HSA-9860931 5.962014e-02 1.225 0 0
Degradation of AXIN R-HSA-4641257 6.012268e-02 1.221 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 6.065478e-02 1.217 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 6.065478e-02 1.217 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 6.065478e-02 1.217 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 6.065478e-02 1.217 0 0
PCP/CE pathway R-HSA-4086400 6.087669e-02 1.216 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 6.179910e-02 1.209 0 0
TBC/RABGAPs R-HSA-8854214 6.181675e-02 1.209 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 6.181675e-02 1.209 0 0
Co-inhibition by CTLA4 R-HSA-389513 6.248133e-02 1.204 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 6.262446e-02 1.203 0 0
SHC1 events in EGFR signaling R-HSA-180336 6.262446e-02 1.203 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 6.262446e-02 1.203 0 0
Translesion synthesis by REV1 R-HSA-110312 6.262446e-02 1.203 0 0
Protein methylation R-HSA-8876725 6.262446e-02 1.203 0 0
p75NTR signals via NF-kB R-HSA-193639 6.262446e-02 1.203 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 6.262446e-02 1.203 0 0
Adaptive Immune System R-HSA-1280218 6.347304e-02 1.197 0 0
Diseases of mitotic cell cycle R-HSA-9675126 6.455992e-02 1.190 0 0
Signaling by FGFR R-HSA-190236 6.552249e-02 1.184 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 6.790356e-02 1.168 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 6.832606e-02 1.165 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.873709e-02 1.163 0 0
Hedgehog ligand biogenesis R-HSA-5358346 6.873709e-02 1.163 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 6.874867e-02 1.163 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 6.879130e-02 1.162 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 7.000119e-02 1.155 0 0
Intracellular signaling by second messengers R-HSA-9006925 7.090701e-02 1.149 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 7.223934e-02 1.141 0 0
Early Phase of HIV Life Cycle R-HSA-162594 7.233975e-02 1.141 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 7.233975e-02 1.141 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 7.249400e-02 1.140 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 7.249400e-02 1.140 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 7.328851e-02 1.135 0 0
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) R-HSA-1299308 7.353219e-02 1.134 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 7.353219e-02 1.134 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 7.353219e-02 1.134 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 7.422376e-02 1.129 0 0
Translesion synthesis by POLI R-HSA-5656121 7.422376e-02 1.129 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 7.422376e-02 1.129 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 7.422376e-02 1.129 0 0
Death Receptor Signaling R-HSA-73887 7.427627e-02 1.129 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 7.446493e-02 1.128 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 7.522401e-02 1.124 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 7.525508e-02 1.123 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 7.525508e-02 1.123 0 0
Synthesis of DNA R-HSA-69239 7.693743e-02 1.114 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 7.795233e-02 1.108 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 7.795233e-02 1.108 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 7.961016e-02 1.099 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 7.981642e-02 1.098 0 0
RAB geranylgeranylation R-HSA-8873719 8.103231e-02 1.091 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 8.132335e-02 1.090 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 8.208514e-02 1.086 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 8.236115e-02 1.084 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.236115e-02 1.084 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 8.236115e-02 1.084 0 0
Diseases of DNA repair R-HSA-9675135 8.260678e-02 1.083 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 8.303687e-02 1.081 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 8.344847e-02 1.079 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 8.363611e-02 1.078 0 0
Disease R-HSA-1643685 8.588993e-02 1.066 0 0
Disorders of Developmental Biology R-HSA-9675151 8.690694e-02 1.061 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 8.690694e-02 1.061 0 0
Translesion synthesis by POLK R-HSA-5655862 8.690694e-02 1.061 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 8.690694e-02 1.061 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 8.690694e-02 1.061 0 0
NF-kB is activated and signals survival R-HSA-209560 8.760432e-02 1.057 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 8.760432e-02 1.057 0 0
Formation of paraxial mesoderm R-HSA-9793380 8.778765e-02 1.057 0 0
HIV elongation arrest and recovery R-HSA-167287 8.778913e-02 1.057 0 0
Pausing and recovery of HIV elongation R-HSA-167290 8.778913e-02 1.057 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 8.778913e-02 1.057 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 8.889648e-02 1.051 0 0
Potential therapeutics for SARS R-HSA-9679191 8.975507e-02 1.047 0 0
Dual Incision in GG-NER R-HSA-5696400 9.005844e-02 1.045 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 9.005844e-02 1.045 0 0
Signaling by NOTCH1 R-HSA-1980143 9.007191e-02 1.045 0 0
Downstream TCR signaling R-HSA-202424 9.056961e-02 1.043 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 9.074225e-02 1.042 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 9.074225e-02 1.042 0 0
MyD88-independent TLR4 cascade R-HSA-166166 9.193101e-02 1.037 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 9.193101e-02 1.037 0 0
Defective OGG1 Localization R-HSA-9657050 1.049291e-01 0.979 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.049291e-01 0.979 0 0
Deletions in the AMER1 gene destabilize the destruction complex R-HSA-5467343 1.049291e-01 0.979 0 0
Defective OGG1 Substrate Binding R-HSA-9656255 1.049291e-01 0.979 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.070550e-01 0.970 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 1.070550e-01 0.970 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 1.070550e-01 0.970 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.437452e-01 0.842 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.437452e-01 0.842 0 0
Signaling by MAP2K mutants R-HSA-9652169 1.437452e-01 0.842 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 1.437452e-01 0.842 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 1.012431e-01 0.995 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 1.012431e-01 0.995 0 0
TRIF-mediated programmed cell death R-HSA-2562578 1.012431e-01 0.995 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 1.825699e-01 0.739 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 1.825699e-01 0.739 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 1.246747e-01 0.904 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 1.044053e-01 0.981 0 0
Pervasive developmental disorders R-HSA-9005895 1.044053e-01 0.981 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.044053e-01 0.981 0 0
Disorders of Nervous System Development R-HSA-9697154 1.044053e-01 0.981 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.225480e-01 0.912 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 1.225480e-01 0.912 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.225480e-01 0.912 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.225480e-01 0.912 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 1.764486e-01 0.753 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 1.006438e-01 0.997 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.006438e-01 0.997 0 0
FGFR2 alternative splicing R-HSA-6803529 9.456164e-02 1.024 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.624171e-01 0.789 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.624171e-01 0.789 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 1.068962e-01 0.971 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 1.068962e-01 0.971 0 0
Termination of translesion DNA synthesis R-HSA-5656169 9.829517e-02 1.007 0 0
Deadenylation of mRNA R-HSA-429947 1.200163e-01 0.921 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 1.477232e-01 0.831 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 1.477232e-01 0.831 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.839001e-01 0.735 0 0
Phosphorylation of the APC/C R-HSA-176412 1.839001e-01 0.735 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.094595e-01 0.961 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 1.651802e-01 0.782 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 1.651802e-01 0.782 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.637640e-01 0.786 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.637640e-01 0.786 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 1.467307e-01 0.833 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 1.436245e-01 0.843 0 0
HIV Transcription Elongation R-HSA-167169 1.558986e-01 0.807 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 1.558986e-01 0.807 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.686514e-01 0.773 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.625585e-01 0.789 0 0
Transcription of the HIV genome R-HSA-167172 1.444627e-01 0.840 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 1.788016e-01 0.748 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 1.065255e-01 0.973 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 9.357249e-02 1.029 0 0
DNA Damage Bypass R-HSA-73893 1.072018e-01 0.970 0 0
PERK regulates gene expression R-HSA-381042 9.968464e-02 1.001 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 1.200163e-01 0.921 0 0
Intra-Golgi traffic R-HSA-6811438 9.960646e-02 1.002 0 0
GPER1 signaling R-HSA-9634597 1.745716e-01 0.758 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.314662e-01 0.881 0 0
Integrin signaling R-HSA-354192 1.467307e-01 0.833 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 1.200163e-01 0.921 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.836845e-01 0.736 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.338919e-01 0.873 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.338919e-01 0.873 0 0
DCC mediated attractive signaling R-HSA-418885 1.624171e-01 0.789 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.302872e-01 0.885 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 1.834068e-01 0.737 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 1.825699e-01 0.739 0 0
Signal amplification R-HSA-392518 1.744910e-01 0.758 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.498364e-01 0.824 0 0
FOXO-mediated transcription R-HSA-9614085 1.113744e-01 0.953 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.225480e-01 0.912 0 0
Platelet calcium homeostasis R-HSA-418360 9.829517e-02 1.007 0 0
TGFBR3 expression R-HSA-9839394 1.338919e-01 0.873 0 0
Budding and maturation of HIV virion R-HSA-162588 1.212669e-01 0.916 0 0
Nuclear RNA decay R-HSA-9930044 1.467307e-01 0.833 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.246747e-01 0.904 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 1.044053e-01 0.981 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.205913e-01 0.919 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 1.311133e-01 0.882 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.671983e-01 0.777 0 0
TNFR1-mediated ceramide production R-HSA-5626978 1.437452e-01 0.842 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 1.651802e-01 0.782 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.960646e-02 1.002 0 0
Fanconi Anemia Pathway R-HSA-6783310 1.397805e-01 0.855 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.256886e-01 0.901 0 0
Ca2+ pathway R-HSA-4086398 1.221360e-01 0.913 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 1.449550e-01 0.839 0 0
Circadian clock R-HSA-9909396 1.546317e-01 0.811 0 0
Proteasome assembly R-HSA-9907900 1.290462e-01 0.889 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.619438e-01 0.791 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.619438e-01 0.791 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.212669e-01 0.916 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 1.419247e-01 0.848 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 1.311060e-01 0.882 0 0
Cellular response to hypoxia R-HSA-1234174 1.181840e-01 0.927 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 1.625585e-01 0.789 0 0
Somitogenesis R-HSA-9824272 1.397805e-01 0.855 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 1.825699e-01 0.739 0 0
Malate-aspartate shuttle R-HSA-9856872 1.419247e-01 0.848 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 9.829517e-02 1.007 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 1.744910e-01 0.758 0 0
Rab regulation of trafficking R-HSA-9007101 1.474810e-01 0.831 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.260666e-01 0.899 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 1.467307e-01 0.833 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 1.049244e-01 0.979 0 0
MTF1 activates gene expression R-HSA-5660489 1.437452e-01 0.842 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 1.825699e-01 0.739 0 0
Unwinding of DNA R-HSA-176974 1.498364e-01 0.824 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.225480e-01 0.912 0 0
The NLRP3 inflammasome R-HSA-844456 1.311060e-01 0.882 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.960646e-02 1.002 0 0
Signaling by NOTCH2 R-HSA-1980145 1.744910e-01 0.758 0 0
MAP kinase activation R-HSA-450294 1.503719e-01 0.823 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.488110e-02 1.023 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 1.050913e-01 0.978 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 1.050913e-01 0.978 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 1.050913e-01 0.978 0 0
Frs2-mediated activation R-HSA-170968 1.225480e-01 0.912 0 0
ER-Phagosome pathway R-HSA-1236974 1.355190e-01 0.868 0 0
Post-translational protein modification R-HSA-597592 1.706844e-01 0.768 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.328185e-01 0.877 0 0
Innate Immune System R-HSA-168249 1.556954e-01 0.808 0 0
Activation of ATR in response to replication stress R-HSA-176187 1.467307e-01 0.833 0 0
NOD1/2 Signaling Pathway R-HSA-168638 1.744910e-01 0.758 0 0
NRIF signals cell death from the nucleus R-HSA-205043 1.419247e-01 0.848 0 0
Prolonged ERK activation events R-HSA-169893 1.839001e-01 0.735 0 0
ABC-family proteins mediated transport R-HSA-382556 1.178806e-01 0.929 0 0
FasL/ CD95L signaling R-HSA-75157 1.070550e-01 0.970 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 1.012431e-01 0.995 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 9.456164e-02 1.024 0 0
Mitochondrial calcium ion transport R-HSA-8949215 1.834068e-01 0.737 0 0
Transmission across Chemical Synapses R-HSA-112315 1.121796e-01 0.950 0 0
Formation of definitive endoderm R-HSA-9823730 1.477232e-01 0.831 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.226803e-01 0.911 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.100810e-01 0.958 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 1.624171e-01 0.789 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.132863e-01 0.946 0 0
Hedgehog 'on' state R-HSA-5632684 1.735720e-01 0.761 0 0
Glycogen metabolism R-HSA-8982491 1.558986e-01 0.807 0 0
Signaling by NTRKs R-HSA-166520 1.184892e-01 0.926 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 1.825699e-01 0.739 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 1.044053e-01 0.981 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 1.044053e-01 0.981 0 0
MET activates RAS signaling R-HSA-8851805 1.044053e-01 0.981 0 0
Gluconeogenesis R-HSA-70263 9.858149e-02 1.006 0 0
Ion transport by P-type ATPases R-HSA-936837 1.817974e-01 0.740 0 0
Maturation of nucleoprotein R-HSA-9694631 1.311060e-01 0.882 0 0
Plasma lipoprotein clearance R-HSA-8964043 1.436245e-01 0.843 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 1.651802e-01 0.782 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.187658e-01 0.925 0 0
NrCAM interactions R-HSA-447038 1.825699e-01 0.739 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 1.839001e-01 0.735 0 0
Assembly Of The HIV Virion R-HSA-175474 1.834068e-01 0.737 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.764486e-01 0.753 0 0
MITF-M-dependent gene expression R-HSA-9856651 1.809895e-01 0.742 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 1.044053e-01 0.981 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 1.477232e-01 0.831 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.044053e-01 0.981 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.624171e-01 0.789 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.624171e-01 0.789 0 0
Glycogen synthesis R-HSA-3322077 1.477232e-01 0.831 0 0
Regulation of BACH1 activity R-HSA-9708530 1.839001e-01 0.735 0 0
STING mediated induction of host immune responses R-HSA-1834941 1.311060e-01 0.882 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.419247e-01 0.848 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 1.850058e-01 0.733 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 1.850058e-01 0.733 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.852288e-01 0.732 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.864323e-01 0.729 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.944432e-01 0.711 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 1.955014e-01 0.709 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.956958e-01 0.708 0 0
Signaling by Erythropoietin R-HSA-9006335 1.961787e-01 0.707 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 1.961787e-01 0.707 0 0
mRNA Capping R-HSA-72086 1.961787e-01 0.707 0 0
Regulation of gene expression in beta cells R-HSA-210745 1.961787e-01 0.707 0 0
Activation, translocation and oligomerization of BAX R-HSA-114294 1.988536e-01 0.701 0 0
Defective OGG1 Substrate Processing R-HSA-9656256 1.988536e-01 0.701 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 1.988536e-01 0.701 0 0
Diseases of Telomere Maintenance R-HSA-9673013 1.988536e-01 0.701 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 1.988536e-01 0.701 0 0
Defective Mismatch Repair Associated With MLH1 R-HSA-5545483 1.988536e-01 0.701 0 0
Defective Mismatch Repair Associated With MSH3 R-HSA-5632927 1.988536e-01 0.701 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 1.988536e-01 0.701 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 1.988536e-01 0.701 0 0
Defective Mismatch Repair Associated With PMS2 R-HSA-5632987 1.988536e-01 0.701 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 1.988536e-01 0.701 0 0
Hereditary fructose intolerance R-HSA-5657560 1.988536e-01 0.701 0 0
TICAM1 deficiency - HSE R-HSA-5602566 1.988536e-01 0.701 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 1.988536e-01 0.701 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 1.988536e-01 0.701 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 1.988536e-01 0.701 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 1.988536e-01 0.701 0 0
Inhibition of PKR R-HSA-169131 1.988536e-01 0.701 0 0
Dual incision in TC-NER R-HSA-6782135 2.025590e-01 0.693 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 2.042357e-01 0.690 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 2.042357e-01 0.690 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 2.062441e-01 0.686 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 2.062441e-01 0.686 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 2.062441e-01 0.686 0 0
Metabolism of proteins R-HSA-392499 2.103228e-01 0.677 0 0
Regulation of beta-cell development R-HSA-186712 2.149161e-01 0.668 0 0
Inositol phosphate metabolism R-HSA-1483249 2.217216e-01 0.654 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 2.218690e-01 0.654 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 2.218690e-01 0.654 0 0
Syndecan interactions R-HSA-3000170 2.218690e-01 0.654 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 2.226778e-01 0.652 0 0
Phosphorylation of Emi1 R-HSA-176417 2.226778e-01 0.652 0 0
Proton/oligopeptide cotransporters R-HSA-427975 2.226778e-01 0.652 0 0
TRAIL signaling R-HSA-75158 2.226778e-01 0.652 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 2.226778e-01 0.652 0 0
Diseases of Base Excision Repair R-HSA-9605308 2.226778e-01 0.652 0 0
DAP12 interactions R-HSA-2172127 2.239726e-01 0.650 0 0
Developmental Cell Lineages R-HSA-9734767 2.244851e-01 0.649 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 2.263537e-01 0.645 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.275687e-01 0.643 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 2.289770e-01 0.640 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 2.293181e-01 0.640 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.293181e-01 0.640 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 2.293181e-01 0.640 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.293181e-01 0.640 0 0
Glycogen storage diseases R-HSA-3229121 2.293181e-01 0.640 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 2.329319e-01 0.633 0 0
Signaling by AMER1 mutants R-HSA-4839748 2.329319e-01 0.633 0 0
Signaling by GSK3beta mutants R-HSA-5339716 2.329319e-01 0.633 0 0
Nucleotide Excision Repair R-HSA-5696398 2.330320e-01 0.633 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 2.387463e-01 0.622 0 0
DAG and IP3 signaling R-HSA-1489509 2.387463e-01 0.622 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 2.387463e-01 0.622 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 2.404984e-01 0.619 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 2.416488e-01 0.617 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.451697e-01 0.611 0 0
G0 and Early G1 R-HSA-1538133 2.487090e-01 0.604 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 2.487090e-01 0.604 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 2.493314e-01 0.603 0 0
G alpha (12/13) signalling events R-HSA-416482 2.511181e-01 0.600 0 0
ABC transporter disorders R-HSA-5619084 2.511181e-01 0.600 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 2.522464e-01 0.598 0 0
Pentose phosphate pathway R-HSA-71336 2.522464e-01 0.598 0 0
Interleukin-17 signaling R-HSA-448424 2.526081e-01 0.598 0 0
GAB1 signalosome R-HSA-180292 2.529915e-01 0.597 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.529915e-01 0.597 0 0
Tie2 Signaling R-HSA-210993 2.529915e-01 0.597 0 0
Signaling by TGFBR3 R-HSA-9839373 2.538389e-01 0.595 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 2.622856e-01 0.581 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 2.622856e-01 0.581 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 2.622856e-01 0.581 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 2.622856e-01 0.581 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 2.622856e-01 0.581 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 2.622856e-01 0.581 0 0
Tight junction interactions R-HSA-420029 2.624863e-01 0.581 0 0
Antigen processing-Cross presentation R-HSA-1236975 2.631065e-01 0.580 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.633727e-01 0.579 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 2.633727e-01 0.579 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.633727e-01 0.579 0 0
Autointegration results in viral DNA circles R-HSA-177539 2.633727e-01 0.579 0 0
CREB phosphorylation R-HSA-199920 2.633727e-01 0.579 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.633727e-01 0.579 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 2.633727e-01 0.579 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 2.670486e-01 0.573 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 2.686944e-01 0.571 0 0
Generation of second messenger molecules R-HSA-202433 2.689318e-01 0.570 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 2.771360e-01 0.557 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.771360e-01 0.557 0 0
Cardiac conduction R-HSA-5576891 2.818778e-01 0.550 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 2.829271e-01 0.548 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 2.829271e-01 0.548 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 2.829271e-01 0.548 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 2.829271e-01 0.548 0 0
Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 R-HSA-5083628 2.829271e-01 0.548 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 2.829271e-01 0.548 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 2.829271e-01 0.548 0 0
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) R-HSA-5619045 2.829271e-01 0.548 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 2.829271e-01 0.548 0 0
Defective HK1 causes hexokinase deficiency (HK deficiency) R-HSA-5619056 2.829271e-01 0.548 0 0
Defective SLC34A2 causes PALM R-HSA-5687583 2.829271e-01 0.548 0 0
TRAF3 deficiency - HSE R-HSA-5602571 2.829271e-01 0.548 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 2.829271e-01 0.548 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 2.829271e-01 0.548 0 0
Transport of connexins along the secretory pathway R-HSA-190827 2.829271e-01 0.548 0 0
Oligomerization of connexins into connexons R-HSA-190704 2.829271e-01 0.548 0 0
NTRK3 as a dependence receptor R-HSA-9603505 2.829271e-01 0.548 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.830490e-01 0.548 0 0
Suppression of phagosomal maturation R-HSA-9637687 2.834037e-01 0.548 0 0
Co-stimulation by CD28 R-HSA-389356 2.848571e-01 0.545 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 2.857114e-01 0.544 0 0
Effects of PIP2 hydrolysis R-HSA-114508 2.857114e-01 0.544 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 2.857114e-01 0.544 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 2.859022e-01 0.544 0 0
Disorders of transmembrane transporters R-HSA-5619115 2.879675e-01 0.541 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 2.920619e-01 0.535 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 2.920619e-01 0.535 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 2.920619e-01 0.535 0 0
Maturation of nucleoprotein R-HSA-9683610 2.920619e-01 0.535 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 2.920619e-01 0.535 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 3.016275e-01 0.521 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 3.016275e-01 0.521 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 3.016275e-01 0.521 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 3.016275e-01 0.521 0 0
Protein hydroxylation R-HSA-9629569 3.016275e-01 0.521 0 0
Translation of Structural Proteins R-HSA-9683701 3.031163e-01 0.518 0 0
MECP2 regulates transcription factors R-HSA-9022707 3.040902e-01 0.517 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 3.040902e-01 0.517 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 3.040902e-01 0.517 0 0
Disinhibition of SNARE formation R-HSA-114516 3.040902e-01 0.517 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 3.040902e-01 0.517 0 0
Microbial modulation of RIPK1-mediated regulated necrosis R-HSA-9686347 3.040902e-01 0.517 0 0
CHL1 interactions R-HSA-447041 3.040902e-01 0.517 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.040902e-01 0.517 0 0
SLC-mediated transport of oligopeptides R-HSA-9959399 3.040902e-01 0.517 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.040902e-01 0.517 0 0
RUNX3 Regulates Immune Response and Cell Migration R-HSA-8949275 3.040902e-01 0.517 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 3.046215e-01 0.516 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.046215e-01 0.516 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 3.046422e-01 0.516 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 3.046422e-01 0.516 0 0
Calnexin/calreticulin cycle R-HSA-901042 3.046422e-01 0.516 0 0
Toll-like Receptor Cascades R-HSA-168898 3.120652e-01 0.506 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 3.177787e-01 0.498 0 0
Iron uptake and transport R-HSA-917937 3.177787e-01 0.498 0 0
Ca-dependent events R-HSA-111996 3.205330e-01 0.494 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 3.220454e-01 0.492 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 3.220454e-01 0.492 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 3.237863e-01 0.490 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 3.260624e-01 0.487 0 0
Formation of the Early Elongation Complex R-HSA-113418 3.260624e-01 0.487 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 3.260624e-01 0.487 0 0
Inflammasomes R-HSA-622312 3.260624e-01 0.487 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 3.263467e-01 0.486 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 3.263467e-01 0.486 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 3.263467e-01 0.486 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.370700e-01 0.472 0 0
Protein-protein interactions at synapses R-HSA-6794362 3.386149e-01 0.470 0 0
Interleukin-1 family signaling R-HSA-446652 3.388781e-01 0.470 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 3.430898e-01 0.465 0 0
GPVI-mediated activation cascade R-HSA-114604 3.430898e-01 0.465 0 0
Calmodulin induced events R-HSA-111933 3.430898e-01 0.465 0 0
CaM pathway R-HSA-111997 3.430898e-01 0.465 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 3.443776e-01 0.463 0 0
Regulation by c-FLIP R-HSA-3371378 3.443776e-01 0.463 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 3.443776e-01 0.463 0 0
Dimerization of procaspase-8 R-HSA-69416 3.443776e-01 0.463 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 3.443776e-01 0.463 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 3.443776e-01 0.463 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 3.443776e-01 0.463 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.443776e-01 0.463 0 0
Adrenoceptors R-HSA-390696 3.443776e-01 0.463 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 3.443776e-01 0.463 0 0
Glucagon-type ligand receptors R-HSA-420092 3.476515e-01 0.459 0 0
Neurexins and neuroligins R-HSA-6794361 3.493323e-01 0.457 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 3.493323e-01 0.457 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 3.511806e-01 0.454 0 0
Ribavirin ADME R-HSA-9755088 3.511806e-01 0.454 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 3.511806e-01 0.454 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 3.511806e-01 0.454 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 3.514786e-01 0.454 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 3.520403e-01 0.453 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 3.520403e-01 0.453 0 0
G beta:gamma signalling through BTK R-HSA-8964315 3.520403e-01 0.453 0 0
Netrin-1 signaling R-HSA-373752 3.558116e-01 0.449 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 3.581821e-01 0.446 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 3.581821e-01 0.446 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 3.581821e-01 0.446 0 0
Defective ABCB6 causes MCOPCB7 R-HSA-5683371 3.581821e-01 0.446 0 0
Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 R-HSA-5083629 3.581821e-01 0.446 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 3.581821e-01 0.446 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 3.581821e-01 0.446 0 0
Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 R-HSA-5083633 3.581821e-01 0.446 0 0
mRNA Editing: A to I Conversion R-HSA-75064 3.581821e-01 0.446 0 0
C6 deamination of adenosine R-HSA-75102 3.581821e-01 0.446 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 3.581821e-01 0.446 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 3.581821e-01 0.446 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 3.693168e-01 0.433 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 3.693168e-01 0.433 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 3.693168e-01 0.433 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 3.735937e-01 0.428 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 3.735937e-01 0.428 0 0
Mitochondrial protein import R-HSA-1268020 3.738393e-01 0.427 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 3.760233e-01 0.425 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.760233e-01 0.425 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 3.760233e-01 0.425 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 3.818713e-01 0.418 0 0
Activation of SMO R-HSA-5635838 3.818713e-01 0.418 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 3.818713e-01 0.418 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 3.819660e-01 0.418 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 3.838770e-01 0.416 0 0
Hypusine synthesis from eIF5A-lysine R-HSA-204626 3.838770e-01 0.416 0 0
CASP8 activity is inhibited R-HSA-5218900 3.838770e-01 0.416 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 3.838770e-01 0.416 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.838770e-01 0.416 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.838770e-01 0.416 0 0
Calcineurin activates NFAT R-HSA-2025928 3.838770e-01 0.416 0 0
ARMS-mediated activation R-HSA-170984 3.838770e-01 0.416 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 3.838770e-01 0.416 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 3.838770e-01 0.416 0 0
Downstream signal transduction R-HSA-186763 3.909895e-01 0.408 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 3.914190e-01 0.407 0 0
Regulation of pyruvate metabolism R-HSA-9861718 3.914190e-01 0.407 0 0
Opioid Signalling R-HSA-111885 3.991324e-01 0.399 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 4.007760e-01 0.397 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 4.007760e-01 0.397 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 4.007760e-01 0.397 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 4.014385e-01 0.396 0 0
Signaling by ALK R-HSA-201556 4.014385e-01 0.396 0 0
RSV-host interactions R-HSA-9833110 4.113433e-01 0.386 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 4.113833e-01 0.386 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 4.113833e-01 0.386 0 0
DNA strand elongation R-HSA-69190 4.126043e-01 0.384 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 4.126043e-01 0.384 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 4.157566e-01 0.381 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 4.208703e-01 0.376 0 0
Neuronal System R-HSA-112316 4.209446e-01 0.376 0 0
Binding and entry of HIV virion R-HSA-173107 4.223104e-01 0.374 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 4.223104e-01 0.374 0 0
MAPK3 (ERK1) activation R-HSA-110056 4.223104e-01 0.374 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.223104e-01 0.374 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 4.223104e-01 0.374 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 4.223104e-01 0.374 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 4.223104e-01 0.374 0 0
Tandem pore domain potassium channels R-HSA-1296346 4.223104e-01 0.374 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 4.253480e-01 0.371 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 4.253480e-01 0.371 0 0
Axonal growth stimulation R-HSA-209563 4.255433e-01 0.371 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 4.255433e-01 0.371 0 0
Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome R-HSA-9944997 4.255433e-01 0.371 0 0
Loss of Function of KMT2D in Kabuki Syndrome R-HSA-9944971 4.255433e-01 0.371 0 0
Defective SLC7A7 causes lysinuric protein intolerance (LPI) R-HSA-5660862 4.255433e-01 0.371 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 4.255433e-01 0.371 0 0
MET interacts with TNS proteins R-HSA-8875513 4.255433e-01 0.371 0 0
Type II Na+/Pi cotransporters R-HSA-427589 4.255433e-01 0.371 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 4.270514e-01 0.370 0 0
Post-translational protein phosphorylation R-HSA-8957275 4.335044e-01 0.363 0 0
G-protein beta:gamma signalling R-HSA-397795 4.341001e-01 0.362 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 4.341001e-01 0.362 0 0
Platelet homeostasis R-HSA-418346 4.358007e-01 0.361 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 4.404405e-01 0.356 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 4.404405e-01 0.356 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 4.404405e-01 0.356 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 4.404405e-01 0.356 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 4.447876e-01 0.352 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 4.483619e-01 0.348 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 4.496564e-01 0.347 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 4.496564e-01 0.347 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 4.496564e-01 0.347 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 4.496564e-01 0.347 0 0
Interleukin-7 signaling R-HSA-1266695 4.496564e-01 0.347 0 0
G-protein mediated events R-HSA-112040 4.512501e-01 0.346 0 0
Resolution of D-Loop Structures R-HSA-5693537 4.554197e-01 0.342 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 4.594353e-01 0.338 0 0
HIV Transcription Initiation R-HSA-167161 4.594353e-01 0.338 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 4.594353e-01 0.338 0 0
Signaling by FGFR1 in disease R-HSA-5655302 4.594353e-01 0.338 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 4.594664e-01 0.338 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 4.594664e-01 0.338 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 4.594664e-01 0.338 0 0
Formation of the posterior neural plate R-HSA-9832991 4.594664e-01 0.338 0 0
Bicarbonate transporters R-HSA-425381 4.594664e-01 0.338 0 0
Ionotropic activity of kainate receptors R-HSA-451306 4.594664e-01 0.338 0 0
vRNP Assembly R-HSA-192905 4.594664e-01 0.338 0 0
Signaling by APC mutants R-HSA-4839744 4.594664e-01 0.338 0 0
Suppression of apoptosis R-HSA-9635465 4.594664e-01 0.338 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 4.594664e-01 0.338 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.594664e-01 0.338 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 4.689262e-01 0.329 0 0
PKA activation in glucagon signalling R-HSA-164378 4.689262e-01 0.329 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 4.689262e-01 0.329 0 0
Mismatch Repair R-HSA-5358508 4.689262e-01 0.329 0 0
Polo-like kinase mediated events R-HSA-156711 4.689262e-01 0.329 0 0
Presynaptic function of Kainate receptors R-HSA-500657 4.689262e-01 0.329 0 0
Synaptic adhesion-like molecules R-HSA-8849932 4.689262e-01 0.329 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 4.689262e-01 0.329 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 4.736264e-01 0.325 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 4.736264e-01 0.325 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.736264e-01 0.325 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 4.736264e-01 0.325 0 0
TRP channels R-HSA-3295583 4.736264e-01 0.325 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 4.736264e-01 0.325 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 4.765102e-01 0.322 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 4.765102e-01 0.322 0 0
Gastrulation R-HSA-9758941 4.857885e-01 0.314 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 4.858383e-01 0.314 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 4.858383e-01 0.314 0 0
Nucleotide catabolism defects R-HSA-9735786 4.858383e-01 0.314 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 4.858383e-01 0.314 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 4.858383e-01 0.314 0 0
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834 4.858383e-01 0.314 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 4.858383e-01 0.314 0 0
SARS-CoV-1-mediated effects on programmed cell death R-HSA-9692913 4.858383e-01 0.314 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 4.858383e-01 0.314 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 4.858383e-01 0.314 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 4.858383e-01 0.314 0 0
NADE modulates death signalling R-HSA-205025 4.858383e-01 0.314 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 4.858383e-01 0.314 0 0
Toxicity of tetanus toxin (tetX) R-HSA-5250982 4.858383e-01 0.314 0 0
SLC transporter disorders R-HSA-5619102 4.861145e-01 0.313 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 4.951900e-01 0.305 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 4.951900e-01 0.305 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.951900e-01 0.305 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 4.951900e-01 0.305 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 4.951900e-01 0.305 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 4.951900e-01 0.305 0 0
Signaling by AXIN mutants R-HSA-4839735 4.951900e-01 0.305 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 4.951900e-01 0.305 0 0
Activation of RAC1 R-HSA-428540 4.951900e-01 0.305 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 4.965160e-01 0.304 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 4.967411e-01 0.304 0 0
E2F mediated regulation of DNA replication R-HSA-113510 4.967411e-01 0.304 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 4.967411e-01 0.304 0 0
Other interleukin signaling R-HSA-449836 4.967411e-01 0.304 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 4.967411e-01 0.304 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 4.967411e-01 0.304 0 0
Pyruvate metabolism R-HSA-70268 4.969227e-01 0.304 0 0
Sensory processing of sound R-HSA-9659379 4.970233e-01 0.304 0 0
Cristae formation R-HSA-8949613 4.971911e-01 0.303 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 4.971911e-01 0.303 0 0
Insulin processing R-HSA-264876 4.971911e-01 0.303 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 4.971911e-01 0.303 0 0
Signaling by FGFR3 in disease R-HSA-5655332 4.971911e-01 0.303 0 0
Aquaporin-mediated transport R-HSA-445717 4.972098e-01 0.303 0 0
PLC beta mediated events R-HSA-112043 4.972098e-01 0.303 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 4.973321e-01 0.303 0 0
Heme signaling R-HSA-9707616 5.132219e-01 0.290 0 0
G1/S-Specific Transcription R-HSA-69205 5.178146e-01 0.286 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 5.178146e-01 0.286 0 0
RNA Polymerase III Transcription R-HSA-74158 5.178146e-01 0.286 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 5.202915e-01 0.284 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 5.202915e-01 0.284 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 5.202915e-01 0.284 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 5.202915e-01 0.284 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 5.238025e-01 0.281 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 5.238025e-01 0.281 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 5.238025e-01 0.281 0 0
tRNA processing R-HSA-72306 5.252116e-01 0.280 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 5.271097e-01 0.278 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 5.293726e-01 0.276 0 0
Leading Strand Synthesis R-HSA-69109 5.293726e-01 0.276 0 0
Polymerase switching R-HSA-69091 5.293726e-01 0.276 0 0
Scavenging by Class F Receptors R-HSA-3000484 5.293726e-01 0.276 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 5.293726e-01 0.276 0 0
Repression of WNT target genes R-HSA-4641265 5.293726e-01 0.276 0 0
Ion channel transport R-HSA-983712 5.329861e-01 0.273 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 5.342744e-01 0.272 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 5.398078e-01 0.268 0 0
IRS activation R-HSA-74713 5.398078e-01 0.268 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 5.398078e-01 0.268 0 0
NTRK2 activates RAC1 R-HSA-9032759 5.398078e-01 0.268 0 0
G2 Phase R-HSA-68911 5.398078e-01 0.268 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 5.398078e-01 0.268 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 5.398078e-01 0.268 0 0
PTK6 Down-Regulation R-HSA-8849472 5.398078e-01 0.268 0 0
Suppression of autophagy R-HSA-9636569 5.398078e-01 0.268 0 0
Muscarinic acetylcholine receptors R-HSA-390648 5.398078e-01 0.268 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 5.398078e-01 0.268 0 0
Reelin signalling pathway R-HSA-8866376 5.398078e-01 0.268 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 5.398078e-01 0.268 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 5.428761e-01 0.265 0 0
Regulation of insulin secretion R-HSA-422356 5.482261e-01 0.261 0 0
G-protein activation R-HSA-202040 5.500430e-01 0.260 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 5.500430e-01 0.260 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 5.500430e-01 0.260 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 5.533196e-01 0.257 0 0
Formation of axial mesoderm R-HSA-9796292 5.619441e-01 0.250 0 0
Processing of SMDT1 R-HSA-8949664 5.619441e-01 0.250 0 0
NRAGE signals death through JNK R-HSA-193648 5.645679e-01 0.248 0 0
Activation of the pre-replicative complex R-HSA-68962 5.649007e-01 0.248 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 5.649007e-01 0.248 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 5.649007e-01 0.248 0 0
Parasite infection R-HSA-9664407 5.712220e-01 0.243 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 5.712220e-01 0.243 0 0
Leishmania phagocytosis R-HSA-9664417 5.712220e-01 0.243 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 5.754091e-01 0.240 0 0
Serine metabolism R-HSA-977347 5.754091e-01 0.240 0 0
NGF-stimulated transcription R-HSA-9031628 5.873796e-01 0.231 0 0
Plus-strand DNA synthesis R-HSA-164525 5.881152e-01 0.231 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 5.881152e-01 0.231 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 5.881152e-01 0.231 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 5.881152e-01 0.231 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 5.881152e-01 0.231 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 5.881152e-01 0.231 0 0
CLEC7A/inflammasome pathway R-HSA-5660668 5.881152e-01 0.231 0 0
Pentose phosphate pathway disease R-HSA-6791465 5.881152e-01 0.231 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 5.881152e-01 0.231 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 5.881152e-01 0.231 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 5.881152e-01 0.231 0 0
Intestinal hexose absorption R-HSA-8981373 5.881152e-01 0.231 0 0
Orexin and neuropeptides FF and QRFP bind to their respective receptors R-HSA-389397 5.881152e-01 0.231 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 5.881152e-01 0.231 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 5.881152e-01 0.231 0 0
Mitochondrial biogenesis R-HSA-1592230 5.902505e-01 0.229 0 0
CRMPs in Sema3A signaling R-HSA-399956 5.928662e-01 0.227 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 5.928662e-01 0.227 0 0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA R-HSA-77310 5.928662e-01 0.227 0 0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA R-HSA-77348 5.928662e-01 0.227 0 0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA R-HSA-77350 5.928662e-01 0.227 0 0
Acyl chain remodeling of CL R-HSA-1482798 5.928662e-01 0.227 0 0
Zinc transporters R-HSA-435354 5.928662e-01 0.227 0 0
Signal regulatory protein family interactions R-HSA-391160 5.928662e-01 0.227 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 5.958303e-01 0.225 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 5.958303e-01 0.225 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 5.966230e-01 0.224 0 0
Translation of Structural Proteins R-HSA-9694635 5.990004e-01 0.223 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 5.998599e-01 0.222 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 5.998599e-01 0.222 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 5.998599e-01 0.222 0 0
LDL clearance R-HSA-8964038 5.998599e-01 0.222 0 0
Cellular hexose transport R-HSA-189200 5.998599e-01 0.222 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 5.998599e-01 0.222 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.069982e-01 0.217 0 0
Signaling by WNT in cancer R-HSA-4791275 6.071268e-01 0.217 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 6.141999e-01 0.212 0 0
Parasitic Infection Pathways R-HSA-9824443 6.181596e-01 0.209 0 0
Leishmania infection R-HSA-9658195 6.181596e-01 0.209 0 0
Signaling by FGFR2 in disease R-HSA-5655253 6.209701e-01 0.207 0 0
Formation of the anterior neural plate R-HSA-9823739 6.221261e-01 0.206 0 0
Growth hormone receptor signaling R-HSA-982772 6.233660e-01 0.205 0 0
Signaling by LTK in cancer R-HSA-9842640 6.313542e-01 0.200 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 6.313542e-01 0.200 0 0
G2/M DNA replication checkpoint R-HSA-69478 6.313542e-01 0.200 0 0
Uncoating of the HIV Virion R-HSA-162585 6.313542e-01 0.200 0 0
H139Hfs13* PPM1K causes a mild variant of MSUD R-HSA-9912529 6.313542e-01 0.200 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 6.313542e-01 0.200 0 0
Abacavir transmembrane transport R-HSA-2161517 6.313542e-01 0.200 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 6.313542e-01 0.200 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 6.313542e-01 0.200 0 0
VLDL assembly R-HSA-8866423 6.313542e-01 0.200 0 0
Leukotriene receptors R-HSA-391906 6.313542e-01 0.200 0 0
HDL clearance R-HSA-8964011 6.313542e-01 0.200 0 0
COPII-mediated vesicle transport R-HSA-204005 6.335813e-01 0.198 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 6.401050e-01 0.194 0 0
Thromboxane signalling through TP receptor R-HSA-428930 6.459081e-01 0.190 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 6.467465e-01 0.189 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 6.494268e-01 0.187 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 6.497321e-01 0.187 0 0
Phase 4 - resting membrane potential R-HSA-5576886 6.497321e-01 0.187 0 0
Atorvastatin ADME R-HSA-9754706 6.497321e-01 0.187 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 6.497321e-01 0.187 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 6.497321e-01 0.187 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 6.499579e-01 0.187 0 0
Signaling by PDGF R-HSA-186797 6.568646e-01 0.183 0 0
Adipogenesis R-HSA-9843745 6.603149e-01 0.180 0 0
HDMs demethylate histones R-HSA-3214842 6.674760e-01 0.176 0 0
G protein gated Potassium channels R-HSA-1296059 6.674760e-01 0.176 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 6.674760e-01 0.176 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 6.674760e-01 0.176 0 0
Acyl chain remodelling of PS R-HSA-1482801 6.674760e-01 0.176 0 0
Formation of the nephric duct R-HSA-9830364 6.674760e-01 0.176 0 0
DAG1 core M1 glycosylations R-HSA-8932506 6.700564e-01 0.174 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 6.700564e-01 0.174 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 6.700564e-01 0.174 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 6.700564e-01 0.174 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.700564e-01 0.174 0 0
Mitochondrial ABC transporters R-HSA-1369007 6.700564e-01 0.174 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 6.700564e-01 0.174 0 0
VLDL clearance R-HSA-8964046 6.700564e-01 0.174 0 0
LDL remodeling R-HSA-8964041 6.700564e-01 0.174 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 6.700564e-01 0.174 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 6.700564e-01 0.174 0 0
Netrin mediated repulsion signals R-HSA-418886 6.700564e-01 0.174 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 6.700564e-01 0.174 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 6.700564e-01 0.174 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 6.747071e-01 0.171 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 6.757089e-01 0.170 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 6.757089e-01 0.170 0 0
Fibronectin matrix formation R-HSA-1566977 6.757089e-01 0.170 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 6.757089e-01 0.170 0 0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA R-HSA-77346 6.757089e-01 0.170 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 6.757089e-01 0.170 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 6.757089e-01 0.170 0 0
Synthesis of PG R-HSA-1483148 6.757089e-01 0.170 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 6.757089e-01 0.170 0 0
Response to metal ions R-HSA-5660526 6.757089e-01 0.170 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 6.836269e-01 0.165 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 6.836269e-01 0.165 0 0
Signaling by FGFR in disease R-HSA-1226099 6.871052e-01 0.163 0 0
MET activates PTK2 signaling R-HSA-8874081 6.880672e-01 0.162 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 6.880672e-01 0.162 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 6.880672e-01 0.162 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 6.909716e-01 0.161 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 6.925650e-01 0.160 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 7.000943e-01 0.155 0 0
Specification of primordial germ cells R-HSA-9827857 7.000943e-01 0.155 0 0
RET signaling R-HSA-8853659 7.010197e-01 0.154 0 0
RUNX2 regulates bone development R-HSA-8941326 7.010197e-01 0.154 0 0
Reverse Transcription of HIV RNA R-HSA-162589 7.046974e-01 0.152 0 0
Minus-strand DNA synthesis R-HSA-164516 7.046974e-01 0.152 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 7.046974e-01 0.152 0 0
phospho-PLA2 pathway R-HSA-111995 7.046974e-01 0.152 0 0
DAG1 core M2 glycosylations R-HSA-8932504 7.046974e-01 0.152 0 0
MET receptor recycling R-HSA-8875656 7.046974e-01 0.152 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 7.046974e-01 0.152 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 7.046974e-01 0.152 0 0
FGFR1b ligand binding and activation R-HSA-190370 7.046974e-01 0.152 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 7.046974e-01 0.152 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 7.046974e-01 0.152 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 7.046974e-01 0.152 0 0
Sodium/Proton exchangers R-HSA-425986 7.046974e-01 0.152 0 0
Intestinal absorption R-HSA-8963676 7.046974e-01 0.152 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 7.046974e-01 0.152 0 0
Interleukin-23 signaling R-HSA-9020933 7.046974e-01 0.152 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.076862e-01 0.150 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.076862e-01 0.150 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 7.134924e-01 0.147 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 7.134924e-01 0.147 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 7.147744e-01 0.146 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 7.188731e-01 0.143 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 7.229360e-01 0.141 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 7.229360e-01 0.141 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 7.229360e-01 0.141 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 7.229360e-01 0.141 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 7.229360e-01 0.141 0 0
Platelet sensitization by LDL R-HSA-432142 7.229360e-01 0.141 0 0
Nephron development R-HSA-9831926 7.229360e-01 0.141 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 7.238593e-01 0.140 0 0
Synthesis of PA R-HSA-1483166 7.252615e-01 0.140 0 0
Telomere Extension By Telomerase R-HSA-171319 7.263434e-01 0.139 0 0
Prednisone ADME R-HSA-9757110 7.263434e-01 0.139 0 0
Pyroptosis R-HSA-5620971 7.263434e-01 0.139 0 0
MET promotes cell motility R-HSA-8875878 7.337062e-01 0.134 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 7.337062e-01 0.134 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 7.337062e-01 0.134 0 0
Integrin cell surface interactions R-HSA-216083 7.354425e-01 0.133 0 0
WNT mediated activation of DVL R-HSA-201688 7.357033e-01 0.133 0 0
MAPK1 (ERK2) activation R-HSA-112411 7.357033e-01 0.133 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 7.357033e-01 0.133 0 0
p75NTR regulates axonogenesis R-HSA-193697 7.357033e-01 0.133 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 7.357033e-01 0.133 0 0
mRNA Editing R-HSA-75072 7.357033e-01 0.133 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 7.357033e-01 0.133 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 7.357033e-01 0.133 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 7.357033e-01 0.133 0 0
Interleukin-1 processing R-HSA-448706 7.357033e-01 0.133 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 7.357033e-01 0.133 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 7.357033e-01 0.133 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 7.357033e-01 0.133 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 7.357033e-01 0.133 0 0
DARPP-32 events R-HSA-180024 7.440542e-01 0.128 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 7.440542e-01 0.128 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 7.442894e-01 0.128 0 0
Rap1 signalling R-HSA-392517 7.442894e-01 0.128 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 7.461004e-01 0.127 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 7.486229e-01 0.126 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 7.490084e-01 0.126 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 7.490084e-01 0.126 0 0
Extension of Telomeres R-HSA-180786 7.510350e-01 0.124 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.608382e-01 0.119 0 0
PI3K/AKT activation R-HSA-198203 7.634552e-01 0.117 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 7.634552e-01 0.117 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 7.634552e-01 0.117 0 0
Signal attenuation R-HSA-74749 7.634552e-01 0.117 0 0
CASP4 inflammasome assembly R-HSA-9948001 7.634552e-01 0.117 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 7.634552e-01 0.117 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 7.634552e-01 0.117 0 0
Receptor Mediated Mitophagy R-HSA-8934903 7.634552e-01 0.117 0 0
Signaling by Leptin R-HSA-2586552 7.634552e-01 0.117 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 7.642150e-01 0.117 0 0
Creatine metabolism R-HSA-71288 7.642150e-01 0.117 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 7.642150e-01 0.117 0 0
Signaling by NODAL R-HSA-1181150 7.642150e-01 0.117 0 0
Stimuli-sensing channels R-HSA-2672351 7.743217e-01 0.111 0 0
Molecules associated with elastic fibres R-HSA-2129379 7.767187e-01 0.110 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 7.775737e-01 0.109 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 7.816004e-01 0.107 0 0
Lagging Strand Synthesis R-HSA-69186 7.827773e-01 0.106 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 7.827773e-01 0.106 0 0
ERK/MAPK targets R-HSA-198753 7.827773e-01 0.106 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 7.827773e-01 0.106 0 0
Protein localization R-HSA-9609507 7.836621e-01 0.106 0 0
DAG1 core M3 glycosylations R-HSA-8932505 7.882946e-01 0.103 0 0
vRNA Synthesis R-HSA-192814 7.882946e-01 0.103 0 0
Chylomicron assembly R-HSA-8963888 7.882946e-01 0.103 0 0
Synthesis of PI R-HSA-1483226 7.882946e-01 0.103 0 0
Propionyl-CoA catabolism R-HSA-71032 7.882946e-01 0.103 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 7.882946e-01 0.103 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 7.882946e-01 0.103 0 0
RUNX2 regulates genes involved in cell migration R-HSA-8941332 7.882946e-01 0.103 0 0
Transport of RCbl within the body R-HSA-9758890 7.882946e-01 0.103 0 0
Interleukin-2 signaling R-HSA-9020558 7.882946e-01 0.103 0 0
Cytoprotection by HMOX1 R-HSA-9707564 7.883034e-01 0.103 0 0
Inwardly rectifying K+ channels R-HSA-1296065 7.917215e-01 0.101 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.917215e-01 0.101 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 7.949599e-01 0.100 0 0
Integration of energy metabolism R-HSA-163685 7.977286e-01 0.098 0 0
Activation of GABAB receptors R-HSA-991365 8.035038e-01 0.095 0 0
GABA B receptor activation R-HSA-977444 8.035038e-01 0.095 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.078445e-01 0.093 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 8.105270e-01 0.091 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 8.105270e-01 0.091 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 8.105270e-01 0.091 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 8.105270e-01 0.091 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 8.105270e-01 0.091 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 8.105270e-01 0.091 0 0
DS-GAG biosynthesis R-HSA-2022923 8.105270e-01 0.091 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 8.115771e-01 0.091 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 8.160789e-01 0.088 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 8.160789e-01 0.088 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 8.160789e-01 0.088 0 0
Cell surface interactions at the vascular wall R-HSA-202733 8.263202e-01 0.083 0 0
Surfactant metabolism R-HSA-5683826 8.269238e-01 0.083 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 8.287554e-01 0.082 0 0
Beta oxidation of myristoyl-CoA to lauroyl-CoA R-HSA-77285 8.304257e-01 0.081 0 0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA R-HSA-77305 8.304257e-01 0.081 0 0
Acetylation R-HSA-156582 8.304257e-01 0.081 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.304257e-01 0.081 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 8.304257e-01 0.081 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 8.304257e-01 0.081 0 0
Synthesis of GDP-mannose R-HSA-446205 8.304257e-01 0.081 0 0
Maple Syrup Urine Disease R-HSA-9865114 8.304257e-01 0.081 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 8.304257e-01 0.081 0 0
Regulation of IFNG signaling R-HSA-877312 8.304257e-01 0.081 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 8.304257e-01 0.081 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 8.304257e-01 0.081 0 0
Signaling by LTK R-HSA-9842663 8.304257e-01 0.081 0 0
OAS antiviral response R-HSA-8983711 8.304257e-01 0.081 0 0
Formation of the ureteric bud R-HSA-9830674 8.309536e-01 0.080 0 0
Biosynthesis of maresins R-HSA-9018682 8.309536e-01 0.080 0 0
eNOS activation R-HSA-203615 8.317549e-01 0.080 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 8.317549e-01 0.080 0 0
Kidney development R-HSA-9830369 8.364657e-01 0.078 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 8.447339e-01 0.073 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 8.447339e-01 0.073 0 0
Mitochondrial RNA degradation R-HSA-9836573 8.447339e-01 0.073 0 0
IRS-mediated signalling R-HSA-112399 8.454571e-01 0.073 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 8.479786e-01 0.072 0 0
Diseases of nucleotide metabolism R-HSA-9735804 8.482357e-01 0.071 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 8.482357e-01 0.071 0 0
FGFR1c ligand binding and activation R-HSA-190373 8.482357e-01 0.071 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 8.482357e-01 0.071 0 0
Interleukin-6 signaling R-HSA-1059683 8.482357e-01 0.071 0 0
Extracellular matrix organization R-HSA-1474244 8.512820e-01 0.070 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.546112e-01 0.068 0 0
FCERI mediated NF-kB activation R-HSA-2871837 8.565159e-01 0.067 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 8.574854e-01 0.067 0 0
Laminin interactions R-HSA-3000157 8.574854e-01 0.067 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 8.574854e-01 0.067 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 8.618621e-01 0.065 0 0
Amino acid transport across the plasma membrane R-HSA-352230 8.630530e-01 0.064 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 8.630530e-01 0.064 0 0
Removal of the Flap Intermediate R-HSA-69166 8.641761e-01 0.063 0 0
Retrograde neurotrophin signalling R-HSA-177504 8.641761e-01 0.063 0 0
Synthesis of IPs in the nucleus R-HSA-1855191 8.641761e-01 0.063 0 0
Hydrolysis of LPC R-HSA-1483115 8.641761e-01 0.063 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 8.641761e-01 0.063 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 8.641761e-01 0.063 0 0
Non-canonical inflammasome activation R-HSA-9686114 8.641761e-01 0.063 0 0
Physiological factors R-HSA-5578768 8.641761e-01 0.063 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 8.641761e-01 0.063 0 0
P2Y receptors R-HSA-417957 8.641761e-01 0.063 0 0
Asparagine N-linked glycosylation R-HSA-446203 8.657876e-01 0.063 0 0
Metal ion SLC transporters R-HSA-425410 8.668256e-01 0.062 0 0
Abacavir ADME R-HSA-2161522 8.692722e-01 0.061 0 0
tRNA Aminoacylation R-HSA-379724 8.712006e-01 0.060 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 8.712006e-01 0.060 0 0
Metabolism of polyamines R-HSA-351202 8.712006e-01 0.060 0 0
Elastic fibre formation R-HSA-1566948 8.747051e-01 0.058 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 8.747051e-01 0.058 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 8.784431e-01 0.056 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 8.784431e-01 0.056 0 0
Processive synthesis on the lagging strand R-HSA-69183 8.784431e-01 0.056 0 0
Protein repair R-HSA-5676934 8.784431e-01 0.056 0 0
Beta oxidation of butanoyl-CoA to acetyl-CoA R-HSA-77352 8.784431e-01 0.056 0 0
Biotin transport and metabolism R-HSA-196780 8.784431e-01 0.056 0 0
Other semaphorin interactions R-HSA-416700 8.784431e-01 0.056 0 0
Signaling by Activin R-HSA-1502540 8.784431e-01 0.056 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 8.789339e-01 0.056 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 8.801563e-01 0.055 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 8.836279e-01 0.054 0 0
Azathioprine ADME R-HSA-9748787 8.836290e-01 0.054 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 8.862678e-01 0.052 0 0
Insulin receptor recycling R-HSA-77387 8.901971e-01 0.051 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 8.912122e-01 0.050 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 8.912122e-01 0.050 0 0
Killing mechanisms R-HSA-9664420 8.912122e-01 0.050 0 0
Fructose catabolism R-HSA-70350 8.912122e-01 0.050 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 8.912122e-01 0.050 0 0
Attachment and Entry R-HSA-9678110 8.912122e-01 0.050 0 0
The phototransduction cascade R-HSA-2514856 8.913163e-01 0.050 0 0
Diseases of Immune System R-HSA-5260271 8.922968e-01 0.049 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.922968e-01 0.049 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.967930e-01 0.047 0 0
Insulin receptor signalling cascade R-HSA-74751 8.997965e-01 0.046 0 0
IGF1R signaling cascade R-HSA-2428924 8.997965e-01 0.046 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.006047e-01 0.045 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.010259e-01 0.045 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.010259e-01 0.045 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 9.026406e-01 0.044 0 0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids R-HSA-77288 9.026406e-01 0.044 0 0
Passive transport by Aquaporins R-HSA-432047 9.026406e-01 0.044 0 0
Galactose catabolism R-HSA-70370 9.026406e-01 0.044 0 0
Coenzyme A biosynthesis R-HSA-196783 9.026406e-01 0.044 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 9.026406e-01 0.044 0 0
tRNA modification in the mitochondrion R-HSA-6787450 9.026406e-01 0.044 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.051816e-01 0.043 0 0
Nucleotide biosynthesis R-HSA-8956320 9.053648e-01 0.043 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.060209e-01 0.043 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 9.076394e-01 0.042 0 0
Scavenging by Class A Receptors R-HSA-3000480 9.076394e-01 0.042 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.076394e-01 0.042 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 9.076394e-01 0.042 0 0
Interleukin-37 signaling R-HSA-9008059 9.079745e-01 0.042 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 9.128691e-01 0.040 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 9.128691e-01 0.040 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 9.128691e-01 0.040 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 9.128691e-01 0.040 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.158170e-01 0.038 0 0
Aspartate and asparagine metabolism R-HSA-8963693 9.158170e-01 0.038 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.174628e-01 0.037 0 0
Paracetamol ADME R-HSA-9753281 9.177796e-01 0.037 0 0
PKA activation R-HSA-163615 9.220235e-01 0.035 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 9.220235e-01 0.035 0 0
FGFR1 ligand binding and activation R-HSA-190242 9.220235e-01 0.035 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.220235e-01 0.035 0 0
Apoptotic factor-mediated response R-HSA-111471 9.220235e-01 0.035 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 9.220235e-01 0.035 0 0
Interferon gamma signaling R-HSA-877300 9.239947e-01 0.034 0 0
Neddylation R-HSA-8951664 9.255843e-01 0.034 0 0
Amine ligand-binding receptors R-HSA-375280 9.269585e-01 0.033 0 0
FGFR1 mutant receptor activation R-HSA-1839124 9.296536e-01 0.032 0 0
Cardiogenesis R-HSA-9733709 9.296536e-01 0.032 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 9.296536e-01 0.032 0 0
Germ layer formation at gastrulation R-HSA-9754189 9.302165e-01 0.031 0 0
Specification of the neural plate border R-HSA-9834899 9.302165e-01 0.031 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.302165e-01 0.031 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.302165e-01 0.031 0 0
Signaling by Insulin receptor R-HSA-74752 9.337373e-01 0.030 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.357373e-01 0.029 0 0
Miscellaneous transport and binding events R-HSA-5223345 9.357373e-01 0.029 0 0
Heme degradation R-HSA-189483 9.357373e-01 0.029 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.375492e-01 0.028 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 9.375492e-01 0.028 0 0
Peroxisomal protein import R-HSA-9033241 9.383219e-01 0.028 0 0
Collagen formation R-HSA-1474290 9.412179e-01 0.026 0 0
GABA receptor activation R-HSA-977443 9.426694e-01 0.026 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 9.441117e-01 0.025 0 0
Matriglycan biosynthesis on DAG1 R-HSA-9939291 9.441117e-01 0.025 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 9.441117e-01 0.025 0 0
Abacavir metabolism R-HSA-2161541 9.441117e-01 0.025 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.441117e-01 0.025 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.441117e-01 0.025 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.464388e-01 0.024 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 9.499850e-01 0.022 0 0
Glutathione synthesis and recycling R-HSA-174403 9.499850e-01 0.022 0 0
Attachment and Entry R-HSA-9694614 9.499850e-01 0.022 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.510944e-01 0.022 0 0
Triglyceride catabolism R-HSA-163560 9.511305e-01 0.022 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.511305e-01 0.022 0 0
Fructose metabolism R-HSA-5652084 9.552414e-01 0.020 0 0
Ethanol oxidation R-HSA-71384 9.552414e-01 0.020 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 9.554280e-01 0.020 0 0
Metabolism of folate and pterines R-HSA-196757 9.554280e-01 0.020 0 0
Collagen chain trimerization R-HSA-8948216 9.554280e-01 0.020 0 0
Synthesis of UDP-N-acetyl-glucosamine R-HSA-446210 9.599456e-01 0.018 0 0
Mitochondrial mRNA modification R-HSA-9937008 9.599456e-01 0.018 0 0
Organic anion transport by SLCO transporters R-HSA-879518 9.599456e-01 0.018 0 0
Carnitine shuttle R-HSA-200425 9.599456e-01 0.018 0 0
Interleukin-20 family signaling R-HSA-8854691 9.599456e-01 0.018 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.623114e-01 0.017 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.624361e-01 0.017 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.629624e-01 0.016 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.635990e-01 0.016 0 0
CYP2E1 reactions R-HSA-211999 9.641556e-01 0.016 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 9.641556e-01 0.016 0 0
Assembly of active LPL and LIPC lipase complexes R-HSA-8963889 9.641556e-01 0.016 0 0
Plasma lipoprotein assembly R-HSA-8963898 9.641556e-01 0.016 0 0
Complex III assembly R-HSA-9865881 9.641556e-01 0.016 0 0
Interleukin-6 family signaling R-HSA-6783589 9.641556e-01 0.016 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.648030e-01 0.016 0 0
Hyaluronan degradation R-HSA-2160916 9.679234e-01 0.014 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.685596e-01 0.014 0 0
FCGR activation R-HSA-2029481 9.712036e-01 0.013 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.712036e-01 0.013 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 9.712953e-01 0.013 0 0
Urea cycle R-HSA-70635 9.712953e-01 0.013 0 0
Sphingolipid catabolism R-HSA-9845614 9.712953e-01 0.013 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 9.712953e-01 0.013 0 0
Diseases of branched-chain amino acid catabolism R-HSA-9865118 9.712953e-01 0.013 0 0
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane R-HSA-83936 9.743129e-01 0.011 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.743129e-01 0.011 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.743129e-01 0.011 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.745266e-01 0.011 0 0
Dectin-2 family R-HSA-5621480 9.748289e-01 0.011 0 0
ECM proteoglycans R-HSA-3000178 9.750692e-01 0.011 0 0
Pyrimidine catabolism R-HSA-73621 9.768198e-01 0.010 0 0
Purine catabolism R-HSA-74259 9.769416e-01 0.010 0 0
Pyrimidine salvage R-HSA-73614 9.770135e-01 0.010 0 0
Potassium Channels R-HSA-1296071 9.781264e-01 0.010 0 0
Methylation R-HSA-156581 9.789126e-01 0.009 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 9.789126e-01 0.009 0 0
Thyroxine biosynthesis R-HSA-209968 9.794303e-01 0.009 0 0
mitochondrial fatty acid beta-oxidation of saturated fatty acids R-HSA-77286 9.808217e-01 0.008 0 0
Neurotransmitter clearance R-HSA-112311 9.815931e-01 0.008 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.815931e-01 0.008 0 0
Cargo concentration in the ER R-HSA-5694530 9.835286e-01 0.007 0 0
Neurotransmitter release cycle R-HSA-112310 9.848502e-01 0.007 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.849364e-01 0.007 0 0
DAG1 glycosylations R-HSA-8931838 9.852607e-01 0.006 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.855957e-01 0.006 0 0
PI Metabolism R-HSA-1483255 9.856666e-01 0.006 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.856714e-01 0.006 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.868107e-01 0.006 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.878114e-01 0.005 0 0
G alpha (s) signalling events R-HSA-418555 9.878785e-01 0.005 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.881978e-01 0.005 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.881978e-01 0.005 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.883964e-01 0.005 0 0
Nicotinate metabolism R-HSA-196807 9.893693e-01 0.005 0 0
Hyaluronan metabolism R-HSA-2142845 9.894391e-01 0.005 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 9.894391e-01 0.005 0 0
RA biosynthesis pathway R-HSA-5365859 9.894391e-01 0.005 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.894391e-01 0.005 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 9.894391e-01 0.005 0 0
Mitochondrial protein degradation R-HSA-9837999 9.896359e-01 0.005 0 0
Transferrin endocytosis and recycling R-HSA-917977 9.905500e-01 0.004 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 9.905500e-01 0.004 0 0
Synthesis of bile acids and bile salts via 24-hydroxycholesterol R-HSA-193775 9.905500e-01 0.004 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.905500e-01 0.004 0 0
Glycosphingolipid transport R-HSA-9845576 9.915440e-01 0.004 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.923771e-01 0.003 0 0
Voltage gated Potassium channels R-HSA-1296072 9.924335e-01 0.003 0 0
NCAM1 interactions R-HSA-419037 9.924335e-01 0.003 0 0
Purine salvage R-HSA-74217 9.932295e-01 0.003 0 0
Transport of small molecules R-HSA-382551 9.935094e-01 0.003 0 0
G alpha (q) signalling events R-HSA-416476 9.937167e-01 0.003 0 0
Formation of the cornified envelope R-HSA-6809371 9.938449e-01 0.003 0 0
Tryptophan catabolism R-HSA-71240 9.945792e-01 0.002 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.945792e-01 0.002 0 0
Interleukin-2 family signaling R-HSA-451927 9.945792e-01 0.002 0 0
Triglyceride metabolism R-HSA-8979227 9.950446e-01 0.002 0 0
Aflatoxin activation and detoxification R-HSA-5423646 9.951496e-01 0.002 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.955965e-01 0.002 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.955965e-01 0.002 0 0
Metabolism of nucleotides R-HSA-15869 9.957437e-01 0.002 0 0
Nucleotide salvage R-HSA-8956321 9.959288e-01 0.002 0 0
Collagen degradation R-HSA-1442490 9.959288e-01 0.002 0 0
Peptide hormone metabolism R-HSA-2980736 9.962189e-01 0.002 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.968911e-01 0.001 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.969722e-01 0.001 0 0
Xenobiotics R-HSA-211981 9.969722e-01 0.001 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.970401e-01 0.001 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.972183e-01 0.001 0 0
Synthesis of PC R-HSA-1483191 9.977731e-01 0.001 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.977890e-01 0.001 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.980744e-01 0.001 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.982172e-01 0.001 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.983162e-01 0.001 0 0
PI3K Cascade R-HSA-109704 9.984049e-01 0.001 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 9.984049e-01 0.001 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.984908e-01 0.001 0 0
Metabolism of porphyrins R-HSA-189445 9.984908e-01 0.001 0 0
Branched-chain amino acid catabolism R-HSA-70895 9.985729e-01 0.001 0 0
Drug ADME R-HSA-9748784 9.986374e-01 0.001 0 0
PPARA activates gene expression R-HSA-1989781 9.987103e-01 0.001 0 0
Aspirin ADME R-HSA-9749641 9.987647e-01 0.001 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.988879e-01 0.000 0 0
Glucuronidation R-HSA-156588 9.989779e-01 0.000 0 0
Chondroitin sulfate/dermatan sulfate metabolism R-HSA-1793185 9.990855e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.990926e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.991819e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.992528e-01 0.000 0 0
Interleukin-10 signaling R-HSA-6783783 9.992528e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.993279e-01 0.000 0 0
Sialic acid metabolism R-HSA-4085001 9.994141e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.994286e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.994434e-01 0.000 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.994482e-01 0.000 0 0
Glutathione conjugation R-HSA-156590 9.994758e-01 0.000 0 0
Signaling by Retinoic Acid R-HSA-5362517 9.994758e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.995684e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.996045e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.996247e-01 0.000 0 0
Digestion and absorption R-HSA-8963743 9.996247e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.996999e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.997029e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.997596e-01 0.000 0 0
O-linked glycosylation of mucins R-HSA-913709 9.997849e-01 0.000 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.998279e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.998279e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.998460e-01 0.000 0 0
Retinoid metabolism and transport R-HSA-975634 9.998460e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.998759e-01 0.000 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 9.998898e-01 0.000 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.998898e-01 0.000 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.999014e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999017e-01 0.000 0 0
Mitochondrial translation elongation R-HSA-5389840 9.999122e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999310e-01 0.000 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.999369e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.999369e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999369e-01 0.000 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.999495e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.999517e-01 0.000 0 0
GPCR downstream signalling R-HSA-388396 9.999563e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999680e-01 0.000 0 0
Respiratory electron transport R-HSA-611105 9.999840e-01 0.000 0 0
Synthesis of substrates in N-glycan biosythesis R-HSA-446219 9.999881e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.999893e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999911e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.999920e-01 0.000 0 0
Mitochondrial translation initiation R-HSA-5368286 9.999946e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999947e-01 0.000 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.999969e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999975e-01 0.000 0 0
Mitochondrial translation termination R-HSA-5419276 9.999986e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999988e-01 0.000 0 0
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein R-HSA-446193 9.999993e-01 0.000 0 0
O-linked glycosylation R-HSA-5173105 9.999994e-01 0.000 0 0
Mitochondrial translation R-HSA-5368287 9.999994e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.999997e-01 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 9.999998e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 1.000000e+00 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Metabolism of steroids R-HSA-8957322 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways