NEK2
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0A2R8Y4L2 | S95 | Sugiyama | HNRNPA1L3 HNRNPA1P48 | RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED |
| A5A3E0 | S1065 | Sugiyama | POTEF A26C1B | ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________ |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | S939 | Sugiyama | POTEF A26C1B | VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE |
| A5A3E0 | T789 | Sugiyama | POTEF A26C1B | YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPVLLTEAT |
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| A6NKT7 | T1500 | Sugiyama | RGPD3 RGP3 | RsstPREsPCGKIAVAVLEEtTRERTDVIQGDDVADAASEV |
| B2RPK0 | S15 | Sugiyama | HMGB1P1 HMG1L1 HMGB1L1 | ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHSDAS |
| B2RPK0 | T22 | Sugiyama | HMGB1P1 HMG1L1 HMGB1L1 | GKGDPKKPRGKMssyAFFVQtCREEHKKKHSDASVNFSEFS |
| O00151 | S31 | Sugiyama | PDLIM1 CLIM1 CLP36 | PGPWGFRLVGGKDFEQPLAIsRVtPGSKAALANLCIGDVIT |
| O14556 | T301 | Sugiyama | GAPDHS GAPD2 GAPDH2 GAPDS HSD-35 HSD35 | ASTGAAKAVTKVIPELKGKLtGMAFRVPTPDVSVVDLTCRL |
| O14777 | S165 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | NDC80 HEC HEC1 KNTC2 | TKFEEEVPRIFKDLGYPFALsKSSMYTVGAPHTWPHIVAAL |
| O14910 | S100 | Sugiyama | LIN7A MALS1 VELI1 | GCPEFRARATAKATVAAFAAsEGHSHPRVVELPKTDEGLGF |
| O14974 | S304 | Sugiyama | PPP1R12A MBS MYPT1 | QKKQNLLHsEKRDKKsPLIEstANMDNNQSQKTFKNKETLI |
| O15013 | S1289 | Sugiyama | ARHGEF10 KIAA0294 | GDSLGSMTQKsDLssssGsLsLsHGsssLEHRSEDsTIyDL |
| O15013 | S1291 | Sugiyama | ARHGEF10 KIAA0294 | SLGSMTQKsDLssssGsLsLsHGsssLEHRSEDsTIyDLLK |
| O15127 | T109 | Sugiyama | SCAMP2 | QEELDRKAAELERKERELQNtVANLHVRQNNWPPLPSWCPV |
| O15360 | T351 | EPSD|PSP | FANCA FAA FACA FANCH | SPVLKASDAVQMQREWsFARtHPLLTSLYRRLFVMLSAEEL |
| O15372 | S290 | Sugiyama | EIF3H EIF3S3 | QQQQKHQYQQRRQQENMQRQsRGEPPLPEEDLsKLFKPPQP |
| O43164 | T200 | Sugiyama | PJA2 KIAA0438 RNF131 | HLQLSAEVVEGSRYQEsLGNtVFELENREAEAYtGLsPPVP |
| O43175 | S287 | Sugiyama | PHGDH PGDH3 | PRDRALVDHENVIsCPHLGAsTKEAQSRCGEEIAVQFVDMV |
| O43615 | T198 | Sugiyama | TIMM44 MIMT44 TIM44 | ALsQGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEFAGDKF |
| O43707 | S507 | Sugiyama | ACTN4 | DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID |
| O43707 | S511 | Sugiyama | ACTN4 | VNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAIDQLHL |
| O43707 | T613 | Sugiyama | ACTN4 | EAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPKR |
| O43852 | S300 | Sugiyama | CALU | NKDGKLTKEEIVDKyDLFVGsQAtDFGEALVRHDEF_____ |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60361 | T79 | Sugiyama | NME2P1 | VAMVWEGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGR |
| O60361 | T88 | Sugiyama | NME2P1 | VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV |
| O60610 | S1235 | Sugiyama | DIAPH1 DIAP1 | KRGPRQANRKAGCAVtSLLAsELtKDDAMAAVPAKVsKNsE |
| O60610 | T1230 | Sugiyama | DIAPH1 DIAP1 | AAFRRKRGPRQANRKAGCAVtSLLAsELtKDDAMAAVPAKV |
| O60664 | S225 | Sugiyama | PLIN3 M6PRBP1 TIP47 | PLTDAELARIAtsLDGFDVAsVQQQRQEQSyFVRLGsLSER |
| O60716 | S617 | Sugiyama | CTNND1 KIAA0384 | AERyQEAAPNVANNtGPHAAsCFGAKKGKDEWFSRGKKPIE |
| O60763 | S751 | Sugiyama | USO1 VDP | EIGRLREEIEELKRNQELLQsQLTEKDSMIENMKSSQtSGT |
| O60814 | S39 | Sugiyama | H2BC12 H2BFT HIRIP1 HIST1H2BK | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| O60841 | S196 | Sugiyama | EIF5B IF2 KIAA0741 | ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN |
| O60927 | T75 | Sugiyama | PPP1R11 HCGV TCTE5 | RRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHR |
| O75369 | T1585 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | RAIVHDNKDGtyAVtyIPDKtGRYMIGVTYGGDDIPLsPyR |
| O75663 | S124 | Sugiyama | TIPRL | VIKPyDWTyTTDYKGTLLGEsLKLKVVPTTDHIDTEKLKAR |
| O75663 | S94 | Sugiyama | TIPRL | RCVNNyQGMLKVACAEEWQEsRtEGEHSKEVIKPyDWTyTT |
| O75663 | T96 | Sugiyama | TIPRL | VNNyQGMLKVACAEEWQEsRtEGEHSKEVIKPyDWTyTTDY |
| O75821 | S189 | Sugiyama | EIF3G EIF3S4 | CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK |
| O75821 | T240 | Sugiyama | EIF3G EIF3S4 | DGAsRRGESMQPNRRADDNAtIRVtNLSEDTRETDLQELFR |
| O75937 | S81 | Sugiyama | DNAJC8 SPF31 HSPC315 HSPC331 | VLQIDPEVTDEEIKKRFRQLsILVHPDKNQDDADRAQKAFE |
| O94776 | S433 | Sugiyama | MTA2 MTA1L1 PID | ATRGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQt |
| O95071 | S1878 | Sugiyama | UBR5 EDD EDD1 HYD KIAA0896 | ALASAGDPGHPNHPLHAsQNsARRERMTAREEASLRTLEGR |
| O95816 | S208 | Sugiyama | BAG2 | IKLLEHSKGAGSKTLQQNAEsRFN_________________ |
| O95831 | S118 | Sugiyama | AIFM1 AIF PDCD8 | RIsGLGLtPEQKQKKAALsAsEGEEVPQDKAPSHVPFLLIG |
| P00338 | S105 | Sugiyama | LDHA PIG19 | VTANsKLVIItAGARQQEGEsRLNLVQRNVNIFKFIIPNVV |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P00338 | S319 | Sugiyama | LDHA PIG19 | GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______ |
| P00505 | T192 | Sugiyama | GOT2 KYAT4 | AGMQLQGyRYYDPKtCGFDFtGAVEDISKIPEQSVLLLHAC |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | S390 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | IIGGGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPG |
| P00558 | S393 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA |
| P00558 | S399 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__ |
| P00558 | T168 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF |
| P02786 | S361 | Sugiyama | TFRC | AAEKLFGNMEGDCPSDWKTDstCRMVTSESKNVKLTVSNVL |
| P04040 | T43 | Sugiyama | CAT | KADVLttGAGNPVGDKLNVItVGPRGPLLVQDVVFTDEMAH |
| P04075 | S176 | Sugiyama | ALDOA ALDA | EHtPsALAIMENANVLARyAsICQQNGIVPIVEPEILPDGD |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S354 | Sugiyama | ALDOA ALDA | ANsLACQGKytPsGQAGAAAsEsLFVsNHAy__________ |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S360 | Sugiyama | ALDOA ALDA | QGKytPsGQAGAAAsEsLFVsNHAy________________ |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T119 | Sugiyama | ALDOA ALDA | KsKGGVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYK |
| P04075 | Y364 | Sugiyama | ALDOA ALDA | tPsGQAGAAAsEsLFVsNHAy____________________ |
| P04083 | S182 | Sugiyama | ANXA1 ANX1 LPC1 | RDLAKDItsDtsGDFRNALLsLAKGDRsEDFGVNEDLADsD |
| P04083 | S201 | Sugiyama | ANXA1 ANX1 LPC1 | LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF |
| P04083 | T88 | Sugiyama | ANXA1 ANX1 LPC1 | ILtKRNNAQRQQIKAAYLQEtGKPLDEtLKKALtGHLEEVV |
| P04083 | T95 | Sugiyama | ANXA1 ANX1 LPC1 | AQRQQIKAAYLQEtGKPLDEtLKKALtGHLEEVVLALLKTP |
| P04406 | S148 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | APMFVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNF |
| P04406 | S151 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T153 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | MGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEG |
| P04406 | T154 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEGL |
| P04406 | T211 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM |
| P04406 | T229 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | AstGAAKAVGKVIPELNGKLtGMAFRVPtANVsVVDLtCRL |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04637 | S315 | PSP | TP53 P53 | PHHELPPGStKRALPNNTsssPQPKKKPLDGEyFTLQIRGR |
| P04792 | S187 | Sugiyama | HSPB1 HSP27 HSP28 | APMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAAK__ |
| P04792 | T180 | Sugiyama | HSPB1 HSP27 HSP28 | EGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsD |
| P05187 | T185 | Sugiyama | ALPP PLAP | VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC |
| P05362 | S444 | Sugiyama | ICAM1 | NPLPELKCLKDGtFPLPIGEsVtVtRDLEGtyLCRARSTQG |
| P05362 | T436 | Sugiyama | ICAM1 | TPMCQAWGNPLPELKCLKDGtFPLPIGEsVtVtRDLEGtyL |
| P05386 | S101 | Sugiyama | RPLP1 RRP1 | APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______ |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S102 | Sugiyama | RPLP2 D11S2243E RPP2 | PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05455 | S325 | Sugiyama | SSB | VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA |
| P05783 | S319 | Sugiyama | KRT18 CYK18 PIG46 | LRRtVQsLEIDLDsMRNLKAsLENsLREVEARYALQMEQLN |
| P05783 | S323 | Sugiyama | KRT18 CYK18 PIG46 | VQsLEIDLDsMRNLKAsLENsLREVEARYALQMEQLNGILL |
| P05783 | S93 | Sugiyama | KRT18 CYK18 PIG46 | GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR |
| P05787 | S258 | Sugiyama | KRT8 CYK8 | QISDTSVVLsMDNSRsLDMDsIIAEVKAQyEDIANRsRAEA |
| P05787 | S274 | Sugiyama | KRT8 CYK8 | LDMDsIIAEVKAQyEDIANRsRAEAEsMyQIKyEELQsLAG |
| P05787 | S280 | Sugiyama | KRT8 CYK8 | IAEVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDL |
| P05787 | S291 | Sugiyama | KRT8 CYK8 | ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN |
| P05787 | S330 | Sugiyama | KRT8 CYK8 | MNRNISRLQAEIEGLKGQRAsLEAAIADAEQRGELAIKDAN |
| P05787 | S410 | Sugiyama | KRT8 CYK8 | TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL |
| P06733 | S14 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S310 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VsIEDPFDQDDWGAWQKFtAsAGIQVVGDDLTVtNPKRIAK |
| P06733 | S349 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV |
| P06733 | S353 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | S40 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK |
| P06733 | T323 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | AWQKFtAsAGIQVVGDDLTVtNPKRIAKAVNEKsCNCLLLK |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | Y44 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK |
| P06744 | T250 | Sugiyama | GPI | LQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFWDWV |
| P06748 | S137 | Sugiyama | NPM1 NPM | VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK |
| P06748 | S43 | Sugiyama | NPM1 NPM | LKADKDyHFKVDNDENEHQLsLRTVsLGAGAKDELHIVEAE |
| P06748 | S70 | EPSD|PSP | NPM1 NPM | GAGAKDELHIVEAEAMNyEGsPIKVtLAtLKMsVQPtVsLG |
| P06748 | S88 | EPSD|PSP | NPM1 NPM | EGsPIKVtLAtLKMsVQPtVsLGGFEItPPVVLRLKCGsGP |
| P06748 | T279 | Sugiyama | NPM1 NPM | GsLPKVEAKFINyVKNCFRMtDQEAIQDLWQWRKsL_____ |
| P07195 | S106 | Sugiyama | LDHB | VtANSKIVVVtAGVRQQEGEsRLNLVQRNVNVFKFIIPQIV |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | S320 | Sugiyama | LDHB | GLtsVINQKLKDDEVAQLKKsADtLWDIQKDLKDL______ |
| P07195 | S44 | Sugiyama | LDHB | ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM |
| P07205 | S390 | Sugiyama | PGK2 PGKB | VIGGGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPG |
| P07205 | S393 | Sugiyama | PGK2 PGKB | GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA |
| P07205 | S399 | Sugiyama | PGK2 PGKB | CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__ |
| P07205 | T168 | Sugiyama | PGK2 PGKB | EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF |
| P07237 | S449 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | ANEVEAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKF |
| P07237 | T453 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | EAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESG |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | S75 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| P07437 | T107 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC |
| P07814 | S330 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | KHRKNPIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGC |
| P07814 | S335 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07814 | S882 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | AQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAK |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S169 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | TVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILH |
| P07900 | S399 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK |
| P07900 | S406 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | RGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKKCLELFtE |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S623 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | tyGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsII |
| P07900 | S641 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD |
| P07900 | T624 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE |
| P07900 | T645 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL |
| P07900 | Y627 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | TANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIEtLR |
| P08195 | S129 | Sugiyama | SLC3A2 MDU1 | DMKEVELNELEPEKQPMNAAsGAAMsLAGAEKNGLVKIKVA |
| P08195 | S134 | Sugiyama | SLC3A2 MDU1 | ELNELEPEKQPMNAAsGAAMsLAGAEKNGLVKIKVAEDEAE |
| P08195 | S253 | Sugiyama | SLC3A2 MDU1 | FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA |
| P08195 | S403 | Sugiyama | SLC3A2 MDU1 | SDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYL |
| P08195 | S408 | Sugiyama | SLC3A2 MDU1 | ILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGN |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | T599 | Sugiyama | SLC3A2 MDU1 | QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH |
| P08195 | Y404 | Sugiyama | SLC3A2 MDU1 | DLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLN |
| P08238 | S164 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | VVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILH |
| P08238 | S391 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK |
| P08238 | S398 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKKCLELFsE |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S482 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | T479 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | tsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAF |
| P08238 | T637 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL |
| P08865 | S75 | Sugiyama | RPSA LAMBR LAMR1 | WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG |
| P08865 | S78 | Sugiyama | RPSA LAMBR LAMR1 | LLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtP |
| P08865 | T94 | Sugiyama | RPSA LAMBR LAMR1 | VsVIssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQA |
| P09104 | S37 | Sugiyama | ENO2 | NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY |
| P09104 | S40 | Sugiyama | ENO2 | VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09104 | Y44 | Sugiyama | ENO2 | LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK |
| P09211 | S66 | Sugiyama | GSTP1 FAEES3 GST3 | ASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQE |
| P09211 | T62 | Sugiyama | GSTP1 FAEES3 GST3 | GsLKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGK |
| P09211 | Y64 | Sugiyama | GSTP1 FAEES3 GST3 | LKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQ |
| P09417 | S163 | Sugiyama | QDPR DHPR SDR33C1 | GTPGMIGYGMAKGAVHQLCQsLAGKNSGMPPGAAAIAVLPV |
| P09429 | S15 | Sugiyama | HMGB1 HMG1 | ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAs |
| P09429 | T22 | Sugiyama | HMGB1 HMG1 | GKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAsVNFsEFs |
| P09651 | S360 | Sugiyama | HNRNPA1 HNRPA1 | PyGGGGQyFAKPRNQGGyGGssssssyGsGRRF________ |
| P09651 | S95 | Sugiyama | HNRNPA1 HNRPA1 | RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| P09651 | Y366 | Sugiyama | HNRNPA1 HNRPA1 | QyFAKPRNQGGyGGssssssyGsGRRF______________ |
| P09923 | T182 | Sugiyama | ALPI | VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC |
| P09972 | S176 | Sugiyama | ALDOC ALDC | ERTPSALAILENANVLARyAsICQQNGIVPIVEPEILPDGD |
| P0CG38 | S1065 | Sugiyama | POTEI | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG38 | T789 | Sugiyama | POTEI | YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP |
| P0CG39 | S1028 | Sugiyama | POTEJ | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | T752 | Sugiyama | POTEJ | YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP |
| P0DJD0 | T1484 | Sugiyama | RGPD1 RANBP2L6 RGP1 | RsstPREsPCGKIAVAVLEEtTRERTDVIQGDDVADAASEV |
| P0DPH7 | T56 | Sugiyama | TUBA3C TUBA2 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| P10412 | T92 | Sugiyama | H1-4 H1F4 HIST1H1E | DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA |
| P10412 | T96 | Sugiyama | H1-4 H1F4 HIST1H1E | NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA |
| P10809 | S67 | Sugiyama | HSPD1 HSP60 | LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK |
| P10809 | T231 | Sugiyama | HSPD1 HSP60 | LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI |
| P10809 | T61 | Sugiyama | HSPD1 HSP60 | LQGVDLLADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVA |
| P11047 | S942 | Sugiyama | LAMC1 LAMB2 | GFYNLQSGQGCERCDCHALGstNGQCDIRTGQCECQPGITG |
| P11047 | T943 | Sugiyama | LAMC1 LAMB2 | FYNLQSGQGCERCDCHALGstNGQCDIRTGQCECQPGITGQ |
| P11142 | S153 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | AyLGKtVTNAVVtVPAyFNDsQRQAtKDAGtIAGLNVLRII |
| P11142 | S329 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | LFRGtLDPVEKALRDAKLDKsQIHDIVLVGGstRIPKIQKL |
| P11142 | S340 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN |
| P11142 | S85 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11142 | T37 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P11142 | T47 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P12004 | S172 | Sugiyama | PCNA | sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE |
| P12004 | T98 | Sugiyama | PCNA | ILKCAGNEDIITLRAEDNADtLALVFEAPNQEKVSDYEMKL |
| P12956 | S306 | Sugiyama | XRCC6 G22P1 | IKLYRETNEPVKTKTRtFNtstGGLLLPsDtKRSQIYGSRQ |
| P12956 | T316 | Sugiyama | XRCC6 G22P1 | VKTKTRtFNtstGGLLLPsDtKRSQIYGSRQIILEKEETEE |
| P12956 | T541 | Sugiyama | XRCC6 G22P1 | LVDEFKELVyPPDyNPEGKVtKRKHDNEGSGSKRPKVEysE |
| P13489 | S178 | Sugiyama | RNH1 PRI RNH | SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP |
| P13489 | S290 | Sugiyama | RNH1 PRI RNH | AKGCGDLCRVLRAKESLKELsLAGNELGDEGARLLCETLLE |
| P13489 | T176 | Sugiyama | RNH1 PRI RNH | AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S38 | Sugiyama | EEF2 EF2 | NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | S595 | PSP | EEF2 EF2 | PVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGLAE |
| P13639 | S732 | Sugiyama | EEF2 EF2 | DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP |
| P13667 | S468 | Sugiyama | PDIA4 ERP70 ERP72 | ytFAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAM |
| P13667 | S482 | Sugiyama | PDIA4 ERP70 ERP72 | VKDLGLsEsGEDVNAAILDEsGKKFAMEPEEFDsDtLREFV |
| P13674 | T140 | Sugiyama | P4HA1 P4HA | YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS |
| P13797 | S110 | Sugiyama | PLS3 | AKTFRKAINRKEGICALGGTsELssEGtQHsysEEEKyAFV |
| P13797 | S114 | Sugiyama | PLS3 | RKAINRKEGICALGGTsELssEGtQHsysEEEKyAFVNWIN |
| P13797 | S326 | Sugiyama | PLS3 | LNQIAPKGQKEGEPRIDINMsGFNETDDLKRAEsMLQQADK |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P13861 | Y105 | Sugiyama | PRKAR2A PKR2 PRKAR2 | DLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVIHPKTDE |
| P13929 | S37 | Sugiyama | ENO3 | NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY |
| P13929 | S40 | Sugiyama | ENO3 | VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P13929 | Y44 | Sugiyama | ENO3 | LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK |
| P13987 | T76 | Sugiyama | CD59 MIC11 MIN1 MIN2 MIN3 MSK21 | AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14314 | S478 | Sugiyama | PRKCSH G19P1 | DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS |
| P14314 | T469 | Sugiyama | PRKCSH G19P1 | WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S77 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs |
| P14618 | T195 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | yVDDGLISLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAA |
| P14618 | T45 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI |
| P14618 | T50 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN |
| P14618 | T87 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | S447 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | PKyLNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRK |
| P14625 | S544 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | LDQyVERMKEKQDKIyFMAGsSRKEAEssPFVERLLKKGyE |
| P14625 | S64 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR |
| P14625 | S650 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | KIEKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtG |
| P14625 | S655 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | VVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtGKDIst |
| P14625 | S680 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | RIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDMLRR |
| P14625 | T450 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | LNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRKTLD |
| P14625 | Y652 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | EKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtGKD |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14868 | S33 | Sugiyama | DARS1 DARS PIG40 | KPREIMDAAEDyAKERyGIssMIQsQEKPDRVLVRVRDLtI |
| P14868 | S37 | Sugiyama | DARS1 DARS PIG40 | IMDAAEDyAKERyGIssMIQsQEKPDRVLVRVRDLtIQKAD |
| P15259 | S189 | Sugiyama | PGAM2 PGAMM | EEIVPQIKAGKRVLIAAHGNsLRGIVKHLEGMSDQAIMELN |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15531 | T103 | Sugiyama | NME1 NDPKA NM23 | VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV |
| P15531 | T94 | Sugiyama | NME1 NDPKA NM23 | VAMVWEGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGR |
| P15880 | T285 | Sugiyama | RPS2 RPS4 | PyQEFtDHLVKtHtRVsVQRtQAPAVATt____________ |
| P16401 | T95 | Sugiyama | H1-5 H1F5 HIST1H1B | DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA |
| P16401 | T99 | Sugiyama | H1-5 H1F5 HIST1H1B | NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA |
| P16402 | T93 | Sugiyama | H1-3 H1F3 HIST1H1D | DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA |
| P16402 | T97 | Sugiyama | H1-3 H1F3 HIST1H1D | NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAASGEG |
| P16403 | T92 | Sugiyama | H1-2 H1F2 HIST1H1C | DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA |
| P16403 | T96 | Sugiyama | H1-2 H1F2 HIST1H1C | NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA |
| P17066 | T49 | Sugiyama | HSPA6 HSP70B' | EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV |
| P17844 | S520 | Sugiyama | DDX5 G17P1 HELR HLR1 | GKRGGFNTFRDRENYDRGYssLLKRDFGAKTQNGVYSAANY |
| P17987 | S35 | Sugiyama | TCP1 CCT1 CCTA | EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT |
| P18669 | S155 | Sugiyama | PGAM1 PGAMA CDABP0006 | NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI |
| P18669 | S189 | Sugiyama | PGAM1 PGAMA CDABP0006 | EEIVPQIKEGKRVLIAAHGNsLRGIVKHLEGLSEEAIMELN |
| P18669 | T159 | Sugiyama | PGAM1 PGAMA CDABP0006 | DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK |
| P18754 | S85 | Sugiyama | RCC1 CHC1 | IPEDVVQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsV |
| P18887 | S145 | Sugiyama | XRCC1 | WDRVKIVCSQPYSKDsPFGLsFVRFHsPPDKDEAEAPSQKV |
| P19338 | S458 | Sugiyama | NCL | TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P20073 | S216 | Sugiyama | ANXA7 ANX7 SNX OK/SW-cl.95 | KAMKGFGtDEQAIVDVVANRsNDQRQKIKAAFKTSYGKDLI |
| P20073 | T203 | Sugiyama | ANXA7 ANX7 SNX OK/SW-cl.95 | ANFDAIRDAEILRKAMKGFGtDEQAIVDVVANRsNDQRQKI |
| P20618 | S157 | Sugiyama | PSMB1 PSC5 | IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL |
| P20618 | S162 | Sugiyama | PSMB1 PSC5 | DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG |
| P20810 | S295 | Sugiyama | CAST | QEKKRKVEKDtMsDQALEALsAsLGTRQAEPELDLRsIKEV |
| P20810 | S297 | Sugiyama | CAST | KKRKVEKDtMsDQALEALsAsLGTRQAEPELDLRsIKEVDE |
| P22102 | S106 | Sugiyama | GART PGFT PRGS | LRsAGVQCFGPTAEAAQLEssKRFAKEFMDRHGIPTAQWKA |
| P22234 | S213 | Sugiyama | PAICS ADE2 AIRC PAIS | EFGVDVTTKEIVLADVIDNDsWRLWPSGDRsQQKDKQSYRD |
| P22314 | S46 | Sugiyama | UBA1 A1S9T UBE1 | AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA |
| P22314 | T682 | Sugiyama | UBA1 A1S9T UBE1 | NVNQyLtDPKFVERtLRLAGtQPLEVLEAVQRSLVLQRPQT |
| P22392 | T103 | Sugiyama | NME2 NM23B | VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV |
| P22392 | T94 | Sugiyama | NME2 NM23B | VAMVWEGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGR |
| P22626 | S212 | Sugiyama | HNRNPA2B1 HNRPA2B1 | EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD |
| P22626 | S225 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN |
| P23246 | S283 | Sugiyama | SFPQ PSF | GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN |
| P23284 | S117 | Sugiyama | PPIB CYPB | IKDFMIQGGDFtRGDGtGGKsIyGERFPDENFKLKHyGPGW |
| P23284 | S139 | Sugiyama | PPIB CYPB | yGERFPDENFKLKHyGPGWVsMANAGKDTNGsQFFITTVKT |
| P23381 | S358 | Sugiyama | WARS1 IFI53 WARS WRS | TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs |
| P23381 | S378 | Sugiyama | WARS1 IFI53 WARS WRS | sIFLtDtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDV |
| P23381 | T383 | Sugiyama | WARS1 IFI53 WARS WRS | DtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDVSFMYL |
| P23588 | S122 | Sugiyama | EIF4B | NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA |
| P24752 | S195 | Sugiyama | ACAT1 ACAT MAT | LEDLIVKDGLtDVyNKIHMGsCAENTAKKLNIARNEQDAyA |
| P25398 | S107 | Sugiyama | RPS12 | EWVGLCKIDREGKPRKVVGCsCVVVKDYGKESQAKDVIEEy |
| P25786 | S211 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | GLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDDDVsP |
| P26038 | S576 | Sugiyama | MSN | YKtLRQIRQGNTKQRIDEFEsM___________________ |
| P26232 | S654 | Sugiyama | CTNNA2 CAPR | EELEDDsDFEQEDYDVRsRtsVQtEDDQLIAGQsARAIMAQ |
| P26232 | S667 | Sugiyama | CTNNA2 CAPR | YDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEEKAKIAEQV |
| P26232 | T657 | Sugiyama | CTNNA2 CAPR | EDDsDFEQEDYDVRsRtsVQtEDDQLIAGQsARAIMAQLPQ |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | T148 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV |
| P26373 | T151 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE |
| P26583 | S15 | Sugiyama | HMGB2 HMG2 | ______MGKGDPNKPRGKMssyAFFVQtCREEHKKKHPDss |
| P26583 | T22 | Sugiyama | HMGB2 HMG2 | GKGDPNKPRGKMssyAFFVQtCREEHKKKHPDssVNFAEFS |
| P26639 | S522 | Sugiyama | TARS1 TARS | PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP |
| P26639 | T700 | Sugiyama | TARS1 TARS | EKISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAE |
| P27348 | S145 | Sugiyama | YWHAQ | YFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHP |
| P27348 | S156 | Sugiyama | YWHAQ | DDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLGLALNFSV |
| P27348 | S45 | Sugiyama | YWHAQ | CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI |
| P27695 | S143 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | sDKEGysGVGLLsRQCPLKVsyGIGDEEHDQEGRVIVAEFD |
| P27797 | S189 | Sugiyama | CALR CRTC | THLytLIVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIK |
| P27797 | S193 | Sugiyama | CALR CRTC | tLIVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDA |
| P27797 | S195 | Sugiyama | CALR CRTC | IVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDAsK |
| P27797 | S214 | Sugiyama | CALR CRTC | GsLEDDWDFLPPKKIKDPDAsKPEDWDERAKIDDPtDsKPE |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | S53 | Sugiyama | CALR CRTC | WtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDAR |
| P27797 | S80 | Sugiyama | CALR CRTC | EEKDKGLQTSQDARFyALsAsFEPFSNKGQTLVVQFTVKHE |
| P29144 | S164 | Sugiyama | TPP2 | VALAEACRKQEEFDVANNGSsQANKLIKEELQsQVELLNsF |
| P29401 | S190 | Sugiyama | TKT | ASIYKLDNLVAILDINRLGQsDPAPLQHQMDIyQKRCEAFG |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | S305 | Sugiyama | TKT | LAtPPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQAL |
| P29401 | S548 | Sugiyama | TKT | NIRVLDPFTIKPLDRKLILDsARAtKGRILTVEDHYYEGGI |
| P29401 | T444 | Sugiyama | TKT | DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT |
| P29692 | S60 | Sugiyama | EEF1D EF1D | ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL |
| P29692 | S64 | Sugiyama | EEF1D EF1D | sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI |
| P30041 | S186 | Sugiyama | PRDX6 AOP2 KIAA0106 | SLQLTAEKRVAtPVDWKDGDsVMVLPtIPEEEAKKLFPKGV |
| P30041 | T48 | Sugiyama | PRDX6 AOP2 KIAA0106 | FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL |
| P30041 | T49 | Sugiyama | PRDX6 AOP2 KIAA0106 | LGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKLI |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30050 | T18 | Sugiyama | RPL12 | ___MPPKFDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLs |
| P30050 | T25 | Sugiyama | RPL12 | FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | S60 | Sugiyama | PEBP1 PBP PEBP | VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK |
| P30086 | T167 | Sugiyama | PEBP1 PBP PEBP | GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK |
| P30101 | S98 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | VPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGP |
| P30101 | T102 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRtAD |
| P30101 | T437 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KELGEKLsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsP |
| P31327 | S540 | Sugiyama | CPS1 | LFKRGVLKEYGVKVLGtsVEsIMATEDRQLFSDKLNEINEK |
| P31327 | S564 | Sugiyama | CPS1 | TEDRQLFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPV |
| P31327 | S569 | Sugiyama | CPS1 | LFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPVMIRSA |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P31327 | T326 | Sugiyama | CPS1 | AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP |
| P31327 | T900 | Sugiyama | CPS1 | KMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKC |
| P31939 | S370 | Sugiyama | ATIC PURH OK/SW-cl.86 | ALTILSKKKNGNyCVLQMDQsYKPDENEVRTLFGLHLsQKR |
| P31946 | S47 | Sugiyama | YWHAB | AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P31947 | S45 | Sugiyama | SFN HME1 | FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI |
| P31948 | S42 | Sugiyama | STIP1 | DALQCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDGC |
| P31948 | S45 | Sugiyama | STIP1 | QCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDGCKtV |
| P31948 | S460 | Sugiyama | STIP1 | AMKDytKAMDVYQKALDLDssCKEAADGYQRCMMAQyNRHD |
| P31948 | Y48 | Sugiyama | STIP1 | sEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDGCKtVDLK |
| P32929 | S61 | Sugiyama | CTH | ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA |
| P32929 | S63 | Sugiyama | CTH | LSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGAKY |
| P33176 | S55 | Sugiyama | KIF5B KNS KNS1 | GEDTVVIASKPYAFDRVFQSsTsQEQVyNDCAKKIVKDVLE |
| P33176 | S57 | Sugiyama | KIF5B KNS KNS1 | DTVVIASKPYAFDRVFQSsTsQEQVyNDCAKKIVKDVLEGy |
| P33176 | S718 | Sugiyama | KIF5B KNS KNS1 | KQAVEQQIQSHRETHQKQIssLRDEVEAKAKLITDLQDQNQ |
| P33176 | S950 | Sugiyama | KIF5B KNS KNS1 | PAAsPtHPSAIRGGGAFVQNsQPVAVRGGGGKQV_______ |
| P33316 | S120 | Sugiyama | DUT | PsKRARPAEVGGMQLRFARLsEHAtAPTRGsARAAGYDLYS |
| P33316 | S130 | Sugiyama | DUT | GGMQLRFARLsEHAtAPTRGsARAAGYDLYSAYDYTIPPME |
| P33991 | T856 | Sugiyama | MCM4 CDC21 | TKDMFEEALRALADDDFLtVtGKtVRLL_____________ |
| P33991 | T859 | Sugiyama | MCM4 CDC21 | MFEEALRALADDDFLtVtGKtVRLL________________ |
| P33992 | S424 | Sugiyama | MCM5 CDC46 | tsGKGSSAAGLtAsVMRDPssRNFIMEGGAMVLADGGVVCI |
| P34931 | T39 | Sugiyama | HSPA1L | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P34931 | T49 | Sugiyama | HSPA1L | EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV |
| P35221 | S655 | Sugiyama | CTNNA1 | PEELDDsDFEtEDFDVRsRtsVQtEDDQLIAGQsARAIMAQ |
| P35221 | S668 | Sugiyama | CTNNA1 | FDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEQKAKIAEQV |
| P35221 | S690 | Sugiyama | CTNNA1 | RAIMAQLPQEQKAKIAEQVAsFQEEKSKLDAEVSKWDDSGN |
| P35221 | T658 | Sugiyama | CTNNA1 | LDDsDFEtEDFDVRsRtsVQtEDDQLIAGQsARAIMAQLPQ |
| P35221 | T762 | Sugiyama | CTNNA1 | VISAAKKIAEAGSRMDKLGRtIADHCPDSACKQDLLAYLQR |
| P35579 | S1195 | Sugiyama | MYH9 | TLEEEAKTHEAQIQEMRQKHsQAVEELAEQLEQtKRVKANL |
| P35579 | S1308 | Sugiyama | MYH9 | LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs |
| P35579 | S1713 | Sugiyama | MYH9 | ERAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQ |
| P35579 | S1714 | Sugiyama | MYH9 | RAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQL |
| P35579 | T1208 | Sugiyama | MYH9 | QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE |
| P35579 | T1221 | Sugiyama | MYH9 | LAEQLEQtKRVKANLEKAKQtLENERGELANEVKVLLQGKG |
| P35579 | T1313 | Sugiyama | MYH9 | DSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLstKLKQ |
| P35580 | S1013 | Sugiyama | MYH10 | QNSKFIKEKKLMEDRIAECssQLAEEEEKAKNLAKIRNKQE |
| P35580 | S1699 | Sugiyama | MYH10 | EKKLKSLEAEILQLQEELASsERARRHAEQERDELADEItN |
| P35580 | T1320 | Sugiyama | MYH10 | EKKGIKFAKDAAsLEsQLQDtQELLQEETRQKLNLSSRIRQ |
| P35637 | S462 | Sugiyama | FUS TLS | NECNQCKAPKPDGPGGGPGGsHMGGNyGDDRRGGRGGYDRG |
| P35658 | T860 | Sugiyama | NUP214 CAIN CAN KIAA0023 | LEQKKKQRHLLVPERETLFNtLANNREIINQQRKRLNHLVD |
| P36578 | S63 | Sugiyama | RPL4 RPL1 | NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P36578 | T62 | Sugiyama | RPL4 RPL1 | TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG |
| P36578 | T84 | Sugiyama | RPL4 RPL1 | AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP |
| P36871 | S134 | Sugiyama | PGM1 | LtAsHNPGGPNGDFGIKFNIsNGGPAPEAITDKIFQISKTI |
| P36873 | T307 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | PPP1CC | ETLMCSFQILKPAEKKKPNAtRPVtPPRGMItKQAKK____ |
| P36873 | T318 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | PPP1CC | PAEKKKPNAtRPVtPPRGMItKQAKK_______________ |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37802 | S94 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | QAPVKKIQAstMAFKQMEQIsQFLQAAERYGINTTDIFQtV |
| P37802 | T180 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_ |
| P38117 | T172 | Sugiyama | ETFB FP585 | QVTLEGDKLKVEREIDGGLEtLRLKLPAVVTADLRLNEPRy |
| P38646 | S200 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | NyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNVLRVI |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P38646 | T120 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV |
| P38646 | T86 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK |
| P38646 | Y118 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK |
| P39019 | S59 | Sugiyama | RPS19 | LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY |
| P39019 | T55 | Sugiyama | RPS19 | DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM |
| P39019 | T60 | Sugiyama | RPS19 | AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG |
| P39019 | Y48 | Sugiyama | RPS19 | LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P39023 | S13 | Sugiyama | RPL3 OK/SW-cl.32 | ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP |
| P40227 | S455 | Sugiyama | CCT6A CCT6 CCTZ | LGVQAFADALLIIPKVLAQNsGFDLQEtLVKIQAEHSESGQ |
| P40227 | S49 | Sugiyama | CCT6A CCT6 CCTZ | GLQDVLRTNLGPKGTMKMLVsGAGDIKLTKDGNVLLHEMQI |
| P40227 | T462 | Sugiyama | CCT6A CCT6 CCTZ | DALLIIPKVLAQNsGFDLQEtLVKIQAEHSESGQLVGVDLN |
| P42677 | S78 | Sugiyama | RPS27 MPS1 | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| P42704 | S1026 | Sugiyama | LRPPRC LRP130 | EVPFDVPELWyEDEKHsLNsssAsttEPDFQKDILIACRLN |
| P43243 | S234 | Sugiyama | MATR3 KIAA0723 | yDRMDyEDDRLRDGERCRDDsFFGEtsHNyHKFDsEyERMG |
| P43243 | T239 | Sugiyama | MATR3 KIAA0723 | yEDDRLRDGERCRDDsFFGEtsHNyHKFDsEyERMGRGPGP |
| P46013 | S1329 | Sugiyama | MKI67 | IIIFVGtPVQKLDLtENLtGsKRRPQtPKEEAQALEDLtGF |
| P46060 | S454 | Sugiyama | RANGAP1 KIAA1835 SD | VstFLAFPsPEKLLRLGPKssVLIAQQTDTSDPEKVVSAFL |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46777 | S172 | Sugiyama | RPL5 MSTP030 | RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46777 | T177 | Sugiyama | RPL5 MSTP030 | NKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRK |
| P46782 | S75 | Sugiyama | RPS5 | RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH |
| P46782 | T73 | Sugiyama | RPS5 | AGRYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIV |
| P46783 | S146 | Sugiyama | RPS10 | TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_ |
| P46937 | T143 | SIGNOR|PSP | YAP1 YAP65 | VRAHssPAsLQLGAVsPGtLtPtGVVsGPAAtPTAQHLRQs |
| P47712 | S727 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP |
| P47712 | S729 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA |
| P47756 | S192 | Sugiyama | CAPZB | TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN |
| P47914 | T151 | Sugiyama | RPL29 | DQTKAQAAAPAsVPAQAPKRtQAPtKAsE____________ |
| P48444 | S253 | Sugiyama | ARCN1 COPD | KEVDNFVDKLKsEGEtIMSssMGKRTSEATKMHAPPINMES |
| P48643 | S51 | Sugiyama | CCT5 CCTE KIAA0098 | LEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtVT |
| P48643 | T269 | Sugiyama | CCT5 CCTE KIAA0098 | AILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMI |
| P48643 | T47 | Sugiyama | CCT5 CCTE KIAA0098 | RLMGLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGD |
| P48643 | T50 | Sugiyama | CCT5 CCTE KIAA0098 | GLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtV |
| P48739 | S165 | Sugiyama | PITPNB | DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP |
| P48741 | T49 | Sugiyama | HSPA7 HSP70B | EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV |
| P49023 | S272 | Sugiyama | PXN | QQQtRIsAssAtRELDELMAsLsDFKIQGLEQRADGERCWA |
| P49327 | S1997 | Sugiyama | FASN FAS | DGLLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFV |
| P49327 | S2039 | Sugiyama | FASN FAS | FSSVSCGRGNAGQsNyGFANsAMERICEKRRHEGLPGLAVQ |
| P49327 | S427 | Sugiyama | FASN FAS | NTQPPPAPAPHATLPRLLRAsGRTPEAVQKLLEQGLRHSQD |
| P49327 | T1999 | Sugiyama | FASN FAS | LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF |
| P49368 | T459 | Sugiyama | CCT3 CCTG TRIC5 | AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG |
| P49588 | T181 | Sugiyama | AARS1 AARS | LDDtKILPGNMKDNFWEMGDtGPCGPCsEIHyDRIGGRDAA |
| P49736 | S229 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | sHGHNVFKERIsDMCKENREsLVVNyEDLAAREHVLAYFLP |
| P49792 | T2475 | Sugiyama | RANBP2 NUP358 | RsstPREsPCGKIAVAVLEEtTRERTDVIQGDDVADAtsEV |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50454 | S149 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | KLGsRLyGPssVsFADDFVRssKQHYNCEHSKINFRDKRSA |
| P50897 | T261 | Sugiyama | PPT1 CLN1 PPT | SEWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLV |
| P51955 | S171 | SIGNOR|EPSD|PSP|Sugiyama | NEK2 NEK2A NLK1 | GKQNVKLGDFGLARILNHDtsFAKtFVGtPYYMsPEQMNRM |
| P51955 | S241 | GPS6|SIGNOR|EPSD|PSP | NEK2 NEK2A NLK1 | QKELAGKIREGKFRRIPYRYsDELNEIITRMLNLKDYHRPs |
| P51955 | S261 | Sugiyama | NEK2 NEK2A NLK1 | sDELNEIITRMLNLKDYHRPsVEEILENPLIADLVADEQRR |
| P51955 | S296 | Sugiyama | NEK2 NEK2A NLK1 | ADEQRRNLERRGRQLGEPEKsQDssPVLsELKLKEIQLQER |
| P51955 | S299 | Sugiyama | NEK2 NEK2A NLK1 | QRRNLERRGRQLGEPEKsQDssPVLsELKLKEIQLQERERA |
| P51955 | S356 | EPSD|PSP | NEK2 NEK2A NLK1 | VRERLAEDKLARAENLLKNYsLLKERKFLsLAsNPELLNLP |
| P51955 | S365 | Sugiyama | NEK2 NEK2A NLK1 | LARAENLLKNYsLLKERKFLsLAsNPELLNLPsSVIKKKVH |
| P51955 | S368 | Sugiyama | NEK2 NEK2A NLK1 | AENLLKNYsLLKERKFLsLAsNPELLNLPsSVIKKKVHFSG |
| P51955 | S397 | EPSD|PSP | NEK2 NEK2A NLK1 | sSVIKKKVHFSGESKENIMRsENSEsQLTsKSKCKDLKKRL |
| P51955 | S402 | EPSD|PSP | NEK2 NEK2A NLK1 | KKVHFSGESKENIMRsENSEsQLTsKSKCKDLKKRLHAAQL |
| P51955 | S428 | EPSD|PSP|Sugiyama | NEK2 NEK2A NLK1 | SKCKDLKKRLHAAQLRAQALsDIEKNYQLKsRQILGMR___ |
| P51955 | S43 | Sugiyama | NEK2 NEK2A NLK1 | QKIRRKSDGKILVWKELDYGsMTEAEKQMLVSEVNLLRELK |
| P51955 | T170 | SIGNOR|EPSD|PSP | NEK2 NEK2A NLK1 | DGKQNVKLGDFGLARILNHDtsFAKtFVGtPYYMsPEQMNR |
| P51955 | T175 | GPS6|SIGNOR|EPSD|PSP | NEK2 NEK2A NLK1 | VKLGDFGLARILNHDtsFAKtFVGtPYYMsPEQMNRMSYNE |
| P51955 | T179 | GPS6|SIGNOR|EPSD|PSP | NEK2 NEK2A NLK1 | DFGLARILNHDtsFAKtFVGtPYYMsPEQMNRMSYNEKSDI |
| P52272 | S528 | Sugiyama | HNRNPM HNRPM NAGR1 | IERMGsGVERMGPAIERMGLsMERMVPAGMGAGLERMGPVM |
| P52272 | S633 | Sugiyama | HNRNPM HNRPM NAGR1 | GGGGAsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKAC |
| P52272 | S637 | Sugiyama | HNRNPM HNRPM NAGR1 | AsFDRAIEMERGNFGGsFAGsFGGAGGHAPGVARKACQIFV |
| P52565 | S148 | Sugiyama | ARHGDIA GDIA1 | YIQHTyRKGVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKG |
| P52597 | S107 | Sugiyama | HNRNPF HNRPF | KSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTKEEI |
| P53367 | S293 | Sugiyama | ARFIP1 | DLEELNLGPRDANTLPKIEQsQHLFQAHKEKYDKMRNDVSV |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P53396 | S457 | Sugiyama | ACLY | FLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMPQD |
| P53396 | S459 | Sugiyama | ACLY | LNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMPQDsV |
| P53609 | S347 | Sugiyama | PGGT1B | CGLSLMEESGICKVHPALNVsTRTSERLLDLHQSWKTKDSK |
| P53621 | S389 | Sugiyama | COPA | SYNPAENAVLLCTRAsNLENstyDLytIPKDADsQNPDAPE |
| P53999 | S10 | Sugiyama | SUB1 PC4 RPO2TC1 | ___________MPKSKELVsssssGsDsDsEVDKKLKRKKQ |
| P53999 | S56 | Sugiyama | SUB1 PC4 RPO2TC1 | PVKKQKTGETsRALsssKQssssRDDNMFQIGKMRYVSVRD |
| P54274 | S114 | PSP | TERF1 PIN2 TRBF1 TRF TRF1 | RSEDFRRTRNSAEAIIHGLSsLTACQLRtIYICQFLTRIAA |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P54652 | T38 | Sugiyama | HSPA2 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P54652 | T48 | Sugiyama | HSPA2 | EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI |
| P55060 | S342 | Sugiyama | CSE1L CAS XPO2 | ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF |
| P55060 | S931 | Sugiyama | CSE1L CAS XPO2 | KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL |
| P55072 | S765 | Sugiyama | VCP HEL-220 HEL-S-70 | RsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGAGPsQ |
| P55072 | T761 | Sugiyama | VCP HEL-220 HEL-S-70 | RFARRsVsDNDIRKyEMFAQtLQQsRGFGsFRFPsGNQGGA |
| P55209 | S69 | Sugiyama | NAP1L1 NRP | LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA |
| P56192 | S812 | Sugiyama | MARS1 MARS | GHQIGTVSPLFQKLENDQIEsLRQRFGGGQAKtsPKPAVVE |
| P57053 | S39 | Sugiyama | H2BC12L H2BFS H2BS1 | VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P58546 | T108 | Sugiyama | MTPN | LSKGADKTVKGPDGLTAFEAtDNQAIKALLQ__________ |
| P58876 | S39 | Sugiyama | H2BC5 H2BFB HIRIP2 HIST1H2BD | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | S97 | Sugiyama | TPI1 TPI | GEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELIGQKVAHA |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60174 | T28 | Sugiyama | TPI1 TPI | FVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVVCAPPtAy |
| P60174 | T38 | Sugiyama | TPI1 TPI | RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP |
| P60174 | T46 | Sugiyama | TPI1 TPI | IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN |
| P60174 | T90 | Sugiyama | TPI1 TPI | VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI |
| P60510 | T293 | Sugiyama | PPP4C PPP4 PPX | LELDEHLQKDFIIFEAAPQEtRGIPSKKPVADYFL______ |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60709 | S239 | Sugiyama | ACTB | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P60709 | S300 | Sugiyama | ACTB | NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S365 | Sugiyama | ACTB | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | S60 | Sugiyama | ACTB | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P60709 | T201 | Sugiyama | ACTB | AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL |
| P60709 | T202 | Sugiyama | ACTB | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P60709 | T203 | Sugiyama | ACTB | RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P60709 | T303 | Sugiyama | ACTB | MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P60709 | T89 | Sugiyama | ACTB | YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60709 | Y53 | Sugiyama | ACTB | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P60842 | S78 | Sugiyama | EIF4A1 DDX2A EIF4A | IQQRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDL |
| P61081 | S175 | Sugiyama | UBE2M UBC12 | NNRRLFEQNVQRSMRGGyIGstyFERCLK____________ |
| P61204 | S147 | Sugiyama | ARF3 | KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY |
| P61247 | S238 | Sugiyama | RPS3A FTE1 MFTL | LKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyEP |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61254 | S9 | Sugiyama | RPL26 | ____________MKFNPFVtsDRsKNRKRHFNAPsHIRRKI |
| P61254 | T8 | Sugiyama | RPL26 | _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK |
| P61313 | S97 | Sugiyama | RPL15 EC45 TCBAP0781 | KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN |
| P61604 | T45 | Sugiyama | HSPE1 | TVTKGGIMLPEKSQGKVLQAtVVAVGsGsKGKGGEIQPVsV |
| P61978 | S36 | Sugiyama | HNRNPK HNRPK | NGEFGKRPAEDMEEEQAFKRsRNtDEMVELRILLQSKNAGA |
| P61978 | S401 | Sugiyama | HNRNPK HNRPK | GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | S46 | Sugiyama | YWHAG | AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P61981 | T199 | Sugiyama | YWHAG | YSVFYYEIQNAPEQACHLAKtAFDDAIAELDtLNEDsyKDs |
| P62241 | S160 | Sugiyama | RPS8 OK/SW-cl.83 | KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S46 | Sugiyama | YWHAE | SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI |
| P62263 | S139 | Sugiyama | RPS14 PRO2640 | LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________ |
| P62266 | S45 | Sugiyama | RPS23 | KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA |
| P62273 | S9 | Sugiyama | RPS29 | ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG |
| P62277 | S14 | Sugiyama | RPS13 | _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK |
| P62280 | S67 | Sugiyama | RPS11 | PKEAIEGtyIDKKCPFTGNVsIRGRILsGVVTKMKMQRTIV |
| P62304 | S89 | Sugiyama | SNRPE | KSRKQLGRIMLKGDNITLLQsVsN_________________ |
| P62314 | S59 | Sugiyama | SNRPD1 | HLKAVKMTLKNREPVQLEtLsIRGNNIRYFILPDsLPLDTL |
| P62314 | T57 | Sugiyama | SNRPD1 | NTHLKAVKMTLKNREPVQLEtLsIRGNNIRYFILPDsLPLD |
| P62736 | S241 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | S62 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62736 | Y55 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P62753 | S148 | Sugiyama | RPS6 OK/SW-cl.2 | tVPRRLGPKRASRIRKLFNLsKEDDVRQyVVRKPLNKEGKK |
| P62807 | S39 | Sugiyama | H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI | VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA |
| P62826 | S150 | Sugiyama | RAN ARA24 OK/SW-cl.81 | KVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARKLIG |
| P62826 | T21 | Sugiyama | RAN ARA24 OK/SW-cl.81 | MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA |
| P62857 | T38 | Sugiyama | RPS28 | LGRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtL |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | S14 | Sugiyama | RPL8 | _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62979 | S134 | Sugiyama | RPS27A UBA80 UBCEP1 | IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE |
| P63104 | S145 | Sugiyama | YWHAZ | YYRyLAEVAAGDDKKGIVDQsQQAyQEAFEIsKKEMQPTHP |
| P63104 | S156 | Sugiyama | YWHAZ | DDKKGIVDQsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | S45 | Sugiyama | YWHAZ | CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI |
| P63173 | T14 | Sugiyama | RPL38 | _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF |
| P63220 | S65 | Sugiyama | RPS21 | RFNGQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF__ |
| P63261 | S239 | Sugiyama | ACTG1 ACTG | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63261 | S300 | Sugiyama | ACTG1 ACTG | NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S365 | Sugiyama | ACTG1 ACTG | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | S60 | Sugiyama | ACTG1 ACTG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P63261 | T201 | Sugiyama | ACTG1 ACTG | AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL |
| P63261 | T202 | Sugiyama | ACTG1 ACTG | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P63261 | T203 | Sugiyama | ACTG1 ACTG | RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63261 | T303 | Sugiyama | ACTG1 ACTG | MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63261 | T89 | Sugiyama | ACTG1 ACTG | YPIEHGIVTNWDDMEKIWHHtFyNELRVAPEEHPVLLtEAP |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63261 | Y53 | Sugiyama | ACTG1 ACTG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P63267 | S240 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | S61 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P63267 | Y54 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P67809 | S136 | Sugiyama | YBX1 NSEP1 YB1 | GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR |
| P68032 | S241 | Sugiyama | ACTC1 ACTC | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | S62 | Sugiyama | ACTC1 ACTC | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68032 | T91 | Sugiyama | ACTC1 ACTC | yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68032 | Y55 | Sugiyama | ACTC1 ACTC | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68133 | S241 | Sugiyama | ACTA1 ACTA | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | S62 | Sugiyama | ACTA1 ACTA | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68133 | T91 | Sugiyama | ACTA1 ACTA | yPIEHGIItNWDDMEKIWHHtFyNELRVAPEEHPtLLTEAP |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68133 | Y55 | Sugiyama | ACTA1 ACTA | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68363 | S439 | Sugiyama | TUBA1B | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| P68363 | T56 | Sugiyama | TUBA1B | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T82 | Sugiyama | TUBA1B | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| P68363 | Y83 | Sugiyama | TUBA1B | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| P78347 | S547 | Sugiyama | GTF2I BAP135 WBSCR6 | IIQVGNRIKFVIKRPELLTHsttEVTQPRtNtPVKEDWNVR |
| P78417 | S23 | Sugiyama | GSTO1 GSTTLP28 | GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK |
| P78527 | T2647 | Sugiyama | PRKDC HYRC HYRC1 | ARWPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstDPL |
| P83881 | S79 | Sugiyama | RPL36A RPL44 GIG15 MIG6 | KAKTTKKIVLRLECVEPNCRsKRMLAIKRCKHFELGGDKKR |
| P84077 | S147 | Sugiyama | ARF1 | KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY |
| P84098 | T29 | Sugiyama | RPL19 | RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL |
| Q00610 | S1483 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | VNEsLNNLFITEEDyQALRTsIDAyDNFDNIsLAQRLEKHE |
| Q00610 | S886 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG |
| Q00839 | T582 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | CLGKFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRK |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01105 | S161 | Sugiyama | SET | FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q01105 | T169 | Sugiyama | SET | NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK |
| Q01518 | T165 | Sugiyama | CAP1 CAP | AMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVKA |
| Q01650 | S31 | Sugiyama | SLC7A5 CD98LC LAT1 MPE16 | LAAPAAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNIT |
| Q02539 | T95 | Sugiyama | H1-1 H1F1 HIST1H1A | DVEKNNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKAS |
| Q02539 | T99 | Sugiyama | H1-1 H1F1 HIST1H1A | NNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKASSVET |
| Q02878 | S255 | Sugiyama | RPL6 TXREB1 | tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF |
| Q04760 | T35 | Sugiyama | GLO1 | AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q06265 | S287 | Sugiyama | EXOSC9 PMSCL1 | KALENDQKVRKEGGKFGFAEsIANQRITAFKMEKAPIDtsD |
| Q06323 | S31 | Sugiyama | PSME1 IFI5111 | QAKVDVFREDLCTKtENLLGsyFPKKIsELDAFLKEPALNE |
| Q06830 | S152 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV |
| Q06830 | T156 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG |
| Q06830 | T166 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | DLPVGRsVDEtLRLVQAFQFtDKHGEVCPAGWKPGsDtIKP |
| Q06830 | T18 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | ___MSSGNAKIGHPAPNFKAtAVMPDGQFKDIsLsDyKGKY |
| Q06830 | T183 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | FQFtDKHGEVCPAGWKPGsDtIKPDVQKSKEyFSKQK____ |
| Q08211 | S1026 | Sugiyama | DHX9 DDX9 LKP NDH2 | HKEKRKILTTEGRNALIHKssVNCPFssQDMKYPSPFFVFG |
| Q08211 | S625 | Sugiyama | DHX9 DDX9 LKP NDH2 | DANCNLICGDEyGPETRLsMsQLNEKETPFELIEALLKYIE |
| Q12792 | S140 | Sugiyama | TWF1 PTK9 | EVFGTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKIN |
| Q12792 | S142 | Sugiyama | TWF1 PTK9 | FGTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKINEV |
| Q13098 | S483 | Sugiyama | GPS1 COPS1 CSN1 | QIHVKsPPREGsQGELtPANsQsRMstNM____________ |
| Q13098 | S485 | Sugiyama | GPS1 COPS1 CSN1 | HVKsPPREGsQGELtPANsQsRMstNM______________ |
| Q13148 | S292 | Sugiyama | TARDBP TDP43 | RsGRFGGNPGGFGNQGGFGNsRGGGAGLGNNQGsNMGGGMN |
| Q13263 | T418 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | WTKSAEAFGKIVAERPGtNstGPAPMAPPRAPGPLSKQGsG |
| Q13283 | S362 | Sugiyama | G3BP1 G3BP | LFIGNLPHEVDKSELKDFFQsyGNVVELRINsGGKLPNFGF |
| Q13347 | S217 | Sugiyama | EIF3I EIF3S2 TRIP1 | sRDMtMFVtASKDNTAKLFDsttLEHQKTFRTERPVNSAAL |
| Q13409 | S92 | Sugiyama | DYNC1I2 DNCI2 DNCIC2 | ESPIVFSEYWVPPPMsPSSKsVStPsEAGsQDsGDGAVGsR |
| Q13409 | T617 | Sugiyama | DYNC1I2 DNCI2 DNCIC2 | YDVGEQIAVPRNDEWARFGRtLAEINANRADAEEEAATRIP |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13509 | S75 | Sugiyama | TUBB3 TUBB4 | SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS |
| Q13509 | T107 | Sugiyama | TUBB3 TUBB4 | PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC |
| Q13526 | S108 | Sugiyama | PIN1 | LINGyIQKIKSGEEDFEsLAsQFSDCSsAKARGDLGAFsRG |
| Q13561 | S70 | Sugiyama | DCTN2 DCTN50 | PNAAYDKFKDKRVGTKGLDFsDRIGKTKRtGyEsGEyEMLG |
| Q13564 | S367 | Sugiyama | NAE1 APPBP1 HPP1 | REKAKKDAAAVGNHVAKLLQsIGQAPESISEKELKLLCSNS |
| Q13765 | S186 | Sugiyama | NACA HSD48 | sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q13885 | S75 | Sugiyama | TUBB2A TUBB2 | AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q13885 | T107 | Sugiyama | TUBB2A TUBB2 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q14152 | S1258 | Sugiyama | EIF3A EIF3S10 KIAA0139 | RFRRPRDEGGWRRGPAEEsssWRDssRRDDRDRDDRRRERD |
| Q14152 | S1262 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PRDEGGWRRGPAEEsssWRDssRRDDRDRDDRRRERDDRRD |
| Q14152 | S206 | Sugiyama | EIF3A EIF3S10 KIAA0139 | LQYTRKAEFRKLCDNLRMHLsQIQRHHNQstAINLNNPESQ |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14152 | S988 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN |
| Q14204 | T1309 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | RLKDDREKCAKAKEALELtDtGLLsGSEERVQVALEELQDL |
| Q14240 | S79 | Sugiyama | EIF4A2 DDX2B EIF4F | IQQRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEF |
| Q14247 | S113 | Sugiyama | CTTN EMS1 | DRMDKsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVD |
| Q14444 | T303 | Sugiyama | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 | YTEQSEVESTEYVNRQFMAEtQFtsGEKEQVDEWTVETVEV |
| Q14568 | S169 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | TVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILH |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14676 | T449 | Sugiyama | MDC1 KIAA0170 NFBD1 | RDAEEDMPQRVVLLQRsQtttERDsDtDVEEEELPVENREA |
| Q14697 | S913 | Sugiyama | GANAB G2AN KIAA0088 | VIIGAGKPAAVVLQTKGSPEsRLsFQHDPEtsVLVLRKPGI |
| Q14697 | S916 | Sugiyama | GANAB G2AN KIAA0088 | GAGKPAAVVLQTKGSPEsRLsFQHDPEtsVLVLRKPGINVA |
| Q14697 | T923 | Sugiyama | GANAB G2AN KIAA0088 | VVLQTKGSPEsRLsFQHDPEtsVLVLRKPGINVASDWSIHL |
| Q14974 | S201 | Sugiyama | KPNB1 NTF97 | MRKEEPSNNVKLAAtNALLNsLEFTKANFDKESERHFIMQV |
| Q14974 | T195 | Sugiyama | KPNB1 NTF97 | TAIIQGMRKEEPSNNVKLAAtNALLNsLEFTKANFDKESER |
| Q14980 | S1181 | Sugiyama | NUMA1 NMP22 NUMA | DsALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQD |
| Q14980 | T538 | Sugiyama | NUMA1 NMP22 NUMA | DQELAGLKQQAKEKQAQLAQtLQQQEQASQGLRHQVEQLSs |
| Q15056 | S110 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK |
| Q15056 | S66 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | VGNLPFNTVQGDIDAIFKDLsIRsVRLVRDKDTDKFKGFCy |
| Q15056 | S69 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | LPFNTVQGDIDAIFKDLsIRsVRLVRDKDTDKFKGFCyVEF |
| Q15084 | S375 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | GYPAMAAINARKMKFALLKGsFsEQGINEFLRELsFGRGst |
| Q15181 | S241 | Sugiyama | PPA1 IOPPP PP | KSTHDHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARA |
| Q15181 | T246 | Sugiyama | PPA1 IOPPP PP | HWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDAL |
| Q15185 | S39 | Sugiyama | PTGES3 P23 TEBP | FCVEDSKDVNVNFEKsKLTFsCLGGsDNFKHLNEIDLFHCI |
| Q15185 | S72 | Sugiyama | PTGES3 P23 TEBP | EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE |
| Q15293 | S315 | Sugiyama | RCN1 RCN | NKDEKLTKEEILENWNMFVGsQAtNyGEDLtKNHDEL____ |
| Q15459 | S508 | Sugiyama | SF3A1 SAP114 | IGEEEIQKPEEKVTWDGHsGsMARTQQAAQANITLQEQIEA |
| Q16181 | T318 | Sugiyama | SEPTIN7 CDC10 SEPT7 | KDVTNNVHyENyRSRKLAAVtyNGVDNNKNKGQLtKsPLAQ |
| Q16658 | S127 | Sugiyama | FSCN1 FAN1 HSN SNL | AHRRYFGGtEDRLsCFAQtVsPAEKWSVHIAMHPQVNIYSV |
| Q16658 | S234 | Sugiyama | FSCN1 FAN1 HSN SNL | LEFRsGKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELF |
| Q16658 | T125 | Sugiyama | FSCN1 FAN1 HSN SNL | SEAHRRYFGGtEDRLsCFAQtVsPAEKWSVHIAMHPQVNIY |
| Q16775 | T292 | Sugiyama | HAGH GLO2 HAGH1 | FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____ |
| Q32P51 | S95 | Sugiyama | HNRNPA1L2 HNRNPA1L | TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| Q562R1 | S240 | Sugiyama | ACTBL2 | VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q5FBB7 | S14 | GPS6|SIGNOR|EPSD|PSP | SGO1 SGOL1 | _______MAKERCLKKSFQDsLEDIKKRMKEKRNKNLAEIG |
| Q5FBB7 | S507 | GPS6|SIGNOR|EPSD|PSP | SGO1 SGOL1 | PTLASKLRRGDPFTDLCFLNsPIFKQKKDLRRSKKRALEVS |
| Q5H9R7 | S502 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | QQLIKDLPDEVRERWETFCTsSLGEtNKRNTVDLVttCHIH |
| Q5H9R7 | T507 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | DLPDEVRERWETFCTsSLGEtNKRNTVDLVttCHIHsssDD |
| Q5QNW6 | S39 | Sugiyama | H2BC18 HIST2H2BF | VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q6FI81 | S307 | Sugiyama | CIAPIN1 CUA001 PRO0915 | sCPyLGMPAFKPGEKVLLsDsNLHDA_______________ |
| Q6IBS0 | S140 | Sugiyama | TWF2 PTK9L MSTP011 | ELFGTVKDDLSFAGyQKHLssCAAPAPLtsAERELQQIRIN |
| Q6PEY2 | T56 | Sugiyama | TUBA3E | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| Q6S8J3 | S1065 | Sugiyama | POTEE A26C1A POTE2 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | S939 | Sugiyama | POTEE A26C1A POTE2 | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| Q6S8J3 | T789 | Sugiyama | POTEE A26C1A POTE2 | YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71U36 | S439 | Sugiyama | TUBA1A TUBA3 | SEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy________ |
| Q71U36 | T56 | Sugiyama | TUBA1A TUBA3 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T82 | Sugiyama | TUBA1A TUBA3 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q71U36 | Y83 | Sugiyama | TUBA1A TUBA3 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q71UM5 | S78 | Sugiyama | RPS27L | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| Q7KZF4 | S126 | Sugiyama | SND1 TDRD11 | GREyGMIyLGKDTNGENIAEsLVAEGLAtRREGMRANNPEQ |
| Q7KZF4 | S150 | Sugiyama | SND1 TDRD11 | EGLAtRREGMRANNPEQNRLsECEEQAKAAKKGMWSEGNGS |
| Q7KZF4 | T134 | Sugiyama | SND1 TDRD11 | LGKDTNGENIAEsLVAEGLAtRREGMRANNPEQNRLsECEE |
| Q7Z3J3 | T1500 | Sugiyama | RGPD4 RGP4 | RsstPREsPCGKIAVAVLEEtTRERTDVIQGDDVADAASEV |
| Q8N137 | S36 | EPSD|PSP | CNTROB LIP8 PP1221 | DLLSDSSEPPGLNQVSSEVtsQLYAsLRLsRQAEATARAQL |
| Q8N137 | S41 | EPSD|PSP | CNTROB LIP8 PP1221 | SSEPPGLNQVSSEVtsQLYAsLRLsRQAEATARAQLYLPst |
| Q8N137 | S45 | EPSD|PSP | CNTROB LIP8 PP1221 | PGLNQVSSEVtsQLYAsLRLsRQAEATARAQLYLPstsPPH |
| Q8N137 | T35 | EPSD|PSP | CNTROB LIP8 PP1221 | EDLLSDSSEPPGLNQVSSEVtsQLYAsLRLsRQAEATARAQ |
| Q8NBJ7 | S256 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG |
| Q8NBS9 | S285 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | LLWFRDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETV |
| Q8NBS9 | S292 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | KKVDQYKGKRDLEsLREyVEsQLQRTETGATETVTPSEAPV |
| Q8NE71 | S287 | Sugiyama | ABCF1 ABC50 | YERQVASLKAANAAENDFsVsQAEMSsRQAMLENASDIKLE |
| Q8TAM6 | S280 | Sugiyama | ERMN KIAA1189 | TISYRKIRKGNTKQRIDEFEsMMHL________________ |
| Q8TEQ6 | S1396 | Sugiyama | GEMIN5 | EVQETLAEMIRQHQKSQLCKsTANGPDKNEPEVEAEQPLCs |
| Q8TEQ6 | S1416 | Sugiyama | GEMIN5 | sTANGPDKNEPEVEAEQPLCssQSQCKEEKNEPLSLPELTK |
| Q8WVJ2 | S153 | Sugiyama | NUDCD2 | GFDFsGAEIsGNytKGGPDFsNLEK________________ |
| Q92688 | S104 | Sugiyama | ANP32B APRIL PHAPI2 | AEKLPNLTHLNLsGNKLKDIstLEPLKKLECLKsLDLFNCE |
| Q92734 | S164 | Sugiyama | TFG | REEKsAsDssGKQstQVMAAsMsAFDPLKNQDEINKNVMsA |
| Q92734 | S166 | Sugiyama | TFG | EKsAsDssGKQstQVMAAsMsAFDPLKNQDEINKNVMsAFG |
| Q92734 | S183 | Sugiyama | TFG | AsMsAFDPLKNQDEINKNVMsAFGLtDDQVsGPPsAPAEDR |
| Q92734 | T158 | Sugiyama | TFG | NDTVDGREEKsAsDssGKQstQVMAAsMsAFDPLKNQDEIN |
| Q92997 | S263 | GPS6 | DVL3 KIAA0208 | MSLNIITVTLNMEKYNFLGIsIVGQSNERGDGGIYIGsIMK |
| Q92997 | S280 | EPSD|PSP | DVL3 KIAA0208 | LGIsIVGQSNERGDGGIYIGsIMKGGAVAADGRIEPGDMLL |
| Q92997 | S633 | GPS6 | DVL3 KIAA0208 | LRGPRERAPsERsGPAASEHsHRsHHsLAssLRSHHTHPSY |
| Q92997 | S643 | EPSD|PSP | DVL3 KIAA0208 | ERsGPAASEHsHRsHHsLAssLRSHHTHPSYGPPGVPPLYG |
| Q92997 | S697 | EPSD|PSP | DVL3 KIAA0208 | GPPGAPPGRDLAsVPPELtAsRQsFRMAMGNPSEFFVDVM_ |
| Q92997 | T15 | EPSD|PSP | DVL3 KIAA0208 | ______MGETKIIYHLDGQEtPYLVKLPLPAERVTLADFKG |
| Q93079 | S39 | Sugiyama | H2BC9 H2BFJ HIST1H2BH | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q969Q0 | S79 | Sugiyama | RPL36AL | KAKTTKKIVLRLECVEPNCRsKRMLAIKRCKHFELGGDKKR |
| Q969U7 | S166 | Sugiyama | PSMG2 HCCA3 PAC2 TNFSF5IP1 | SMQKSVQNKIKSLNWEEMEKsRCIPEIDDSEFCIRIPGGGI |
| Q96AG4 | S47 | Sugiyama | LRRC59 PRO1855 | LNEVPVKELAALPKATILDLsCNKLTTLPSDFCGLtHLVKL |
| Q96CN5 | S661 | SIGNOR|PSP | LRRC45 | DEEAQRASFLQNAVLAYVQAsPVRTLSPPK___________ |
| Q96EP5 | S204 | Sugiyama | DAZAP1 | EVKRAEPRDsKsQAPGQPGAsQWGsRVVPNAANGWAGQPPP |
| Q96HE7 | S143 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD |
| Q96IR7 | S360 | Sugiyama | HPDL GLOXD1 | LIQRQGATGFGQGNIRALWQsVQEQsARSQEA_________ |
| Q96QK1 | T773 | Sugiyama | VPS35 MEM3 TCCCTA00141 | DLPNLEssEEtEQINKHFHNtLEHLRLRREsPEsEGPIyEG |
| Q99426 | S163 | Sugiyama | TBCB CG22 CKAP1 | AEAAQRLAEEKAQASSIPVGsRCEVRAAGQSPRRGTVMYVG |
| Q99426 | T120 | Sugiyama | TBCB CG22 CKAP1 | DVSRVEKytIsQEAyDQRQDtVRSFLKRsKLGRyNEEERAQ |
| Q99501 | S352 | SIGNOR|PSP | GAS2L1 GAR22 | PEtPPRPRDQLPPHPRsRRysGDsDssAssAQSGPLGTRSD |
| Q99877 | S39 | Sugiyama | H2BC15 H2BFD HIST1H2BN | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99879 | S39 | Sugiyama | H2BC14 H2BFE HIST1H2BM | INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q99880 | S39 | Sugiyama | H2BC13 H2BFC HIST1H2BL | VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA |
| Q9BQE3 | T56 | Sugiyama | TUBA1C TUBA6 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T82 | Sugiyama | TUBA1C TUBA6 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q9BQE3 | Y83 | Sugiyama | TUBA1C TUBA6 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q9BUJ2 | T113 | Sugiyama | HNRNPUL1 E1BAP5 HNRPUL1 | SGPDGHYAMDNITRQNQFyDtQVIKQENESGyERRPLEMEQ |
| Q9BV73 | S2064 | PSP | CEP250 CEP2 CNAP1 | LAQRDEELRHQQEREQLLEKsLAQRVQENMIQEKQNLGQER |
| Q9BV73 | S2392 | SIGNOR | CEP250 CEP2 CNAP1 | DYITRSAQTSRELAGLHHsLsHsLLAVAQAPEATVLEAETR |
| Q9BV73 | S2394 | SIGNOR | CEP250 CEP2 CNAP1 | ITRSAQTSRELAGLHHsLsHsLLAVAQAPEATVLEAETRRL |
| Q9BV73 | S2417 | GPS6|EPSD|PSP | CEP250 CEP2 CNAP1 | AVAQAPEATVLEAETRRLDEsLTQsLtsPGPVLLHPsPsTT |
| Q9BV73 | S2421 | GPS6|EPSD|PSP | CEP250 CEP2 CNAP1 | APEATVLEAETRRLDEsLTQsLtsPGPVLLHPsPsTTQAAS |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BVA1 | S75 | Sugiyama | TUBB2B | tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q9BVA1 | T107 | Sugiyama | TUBB2B | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q9BWD1 | S208 | Sugiyama | ACAT2 ACTL | RTENAQKAGHFDKEIVPVLVstRKGLIEVKtDEFPRHGsNI |
| Q9BYX7 | S239 | Sugiyama | POTEKP ACTBL3 FKSG30 | VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE |
| Q9BYX7 | S365 | Sugiyama | POTEKP ACTBL3 FKSG30 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9BYX7 | T89 | Sugiyama | POTEKP ACTBL3 FKSG30 | YPMEHGIITNWDDMEKIWHHtFyNELRVAPEEHPILLTEAP |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9C0C2 | S1371 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | QNVELFGAPSEAREHGVGGVsQCPEPGLRHNGsLsPGLEAR |
| Q9GZT8 | T149 | Sugiyama | NIF3L1 ALS2CR1 MDS015 My018 | AYDAAPQGVNNWLAKGLGACtSRPIHPSKAPNyPTEGNHRV |
| Q9H2G2 | T1233 | Sugiyama | SLK KIAA0204 STK2 | LNPStQsRISKFyPIPsLHstGs__________________ |
| Q9H2U2 | S313 | Sugiyama | PPA2 HSPC124 | VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG |
| Q9H788 | S124 | Sugiyama | SH2D4A PPP1R38 SH2A | LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD |
| Q9H788 | Y131 | Sugiyama | SH2D4A PPP1R38 SH2A | EEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKDIWKKVAE |
| Q9H8Y5 | S75 | Sugiyama | ANKZF1 ZNF744 | EsPERKLLQGPMDISEKLFCsTCDQTFQNHQEQREHYKLDW |
| Q9NQ39 | S157 | Sugiyama | RPS10P5 RPS10L | TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_ |
| Q9NUP9 | S85 | Sugiyama | LIN7C MALS3 VELI3 | SSPEVRANATAKATVAAFAAsEGHSHPRVVELPKTEEGLGF |
| Q9NVA2 | S407 | Sugiyama | SEPTIN11 SEPT11 | ELEEEVNNFQKKKAAAQLLQsQAQQSGAQQTKKDKDKKNAS |
| Q9NYL9 | S25 | Sugiyama | TMOD3 | FRKDLEKyKDLDEDELLGNLsEtELKQLETVLDDLDPENAL |
| Q9NZL9 | S16 | Sugiyama | MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 | _____MVGREKELsIHFVPGsCRLVEEEVNIPNRRVLVtGA |
| Q9NZL9 | S9 | Sugiyama | MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 | ____________MVGREKELsIHFVPGsCRLVEEEVNIPNR |
| Q9NZQ7 | T194 | GPS6|SIGNOR|PSP | CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1 | VLSGKTtTTNsKREEKLFNVtsTLRINTTTNEIFYCtFRRL |
| Q9NZQ7 | T210 | GPS6|SIGNOR|PSP | CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1 | LFNVtsTLRINTTTNEIFYCtFRRLDPEENHTAELVIPELP |
| Q9P258 | T20 | Sugiyama | RCC2 KIAA1470 TD60 | _MPRKKAAAAAWEEPssGNGtARAGPRKRGGPAGRKRERPE |
| Q9UBR2 | S78 | Sugiyama | CTSZ | SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST |
| Q9UBS4 | T188 | Sugiyama | DNAJB11 EDJ ERJ3 HDJ9 PSEC0121 UNQ537/PRO1080 | KCNCRQEMRTTQLGPGRFQMtQEVVCDECPNVKLVNEERTL |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UII2 | S39 | Sugiyama | ATP5IF1 ATPI ATPIF1 | TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF |
| Q9UNX3 | S9 | Sugiyama | RPL26L1 RPL26P1 | ____________MKFNPFVtsDRsKNRKRHFNAPSHVRRKI |
| Q9UNX3 | T8 | Sugiyama | RPL26L1 RPL26P1 | _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK |
| Q9UQ35 | S1054 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sLCAGVKsstPPGEsyFGVssLQLKGQsQtsPDHRsDtssP |
| Q9UQ35 | T1043 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | DsLVQsCPGsLsLCAGVKsstPPGEsyFGVssLQLKGQsQt |
| Q9UQ80 | T200 | Sugiyama | PA2G4 EBP1 | TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV |
| Q9UQ80 | T60 | Sugiyama | PA2G4 EBP1 | ssGVsVLsLCEKGDAMIMEEtGKIFKKEKEMKKGIAFPTSI |
| Q9Y262 | S414 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | YGDKMLRMQKGDPQVyEELFsysCPKFLSPVVPNYDNVHPN |
| Q9Y2B0 | S178 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | NVKDKLCSKRtDLCDHALHIsHDEL________________ |
| Q9Y2B0 | S63 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y3B8 | S92 | Sugiyama | REXO2 SFN SMFN CGI-114 | LNILAEGPNLIIKQPDELLDsMSDWCKEHHGKSGLTKAVKE |
| Q9Y3F4 | S230 | Sugiyama | STRAP MAWD UNRIP | SAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLyKy |
| Q9Y3F4 | T225 | Sugiyama | STRAP MAWD UNRIP | SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF |
| Q9Y617 | S43 | Sugiyama | PSAT1 PSA | LEIQKELLDYKGVGIsVLEMsHRssDFAKIINNTENLVREL |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Signal Transduction | R-HSA-162582 | 1.575898e-09 | 8.802 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.865788e-09 | 8.543 | 1 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 3.350615e-09 | 8.475 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 4.541766e-09 | 8.343 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 6.924557e-09 | 8.160 | 1 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.929367e-08 | 7.533 | 1 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.416275e-07 | 6.849 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.761541e-07 | 6.754 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.624480e-07 | 6.581 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 3.896652e-07 | 6.409 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 6.084389e-07 | 6.216 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.084284e-06 | 5.965 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 1.901673e-06 | 5.721 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.157199e-06 | 5.666 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 2.189059e-06 | 5.660 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 3.071606e-06 | 5.513 | 1 | 0 |
| Kinesins | R-HSA-983189 | 3.002575e-06 | 5.523 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 4.015827e-06 | 5.396 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 4.015827e-06 | 5.396 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 4.557291e-06 | 5.341 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 8.051478e-06 | 5.094 | 1 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.019935e-05 | 4.991 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.203868e-05 | 4.919 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.176725e-05 | 4.929 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.242194e-05 | 4.906 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.459850e-05 | 4.836 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 1.514509e-05 | 4.820 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.459850e-05 | 4.836 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 1.945619e-05 | 4.711 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.977619e-05 | 4.704 | 1 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.016496e-05 | 4.520 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.895909e-05 | 4.538 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 2.920045e-05 | 4.535 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 3.425870e-05 | 4.465 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 3.781070e-05 | 4.422 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.883244e-05 | 4.411 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.083215e-05 | 4.389 | 1 | 1 |
| Selective autophagy | R-HSA-9663891 | 4.083215e-05 | 4.389 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 5.348491e-05 | 4.272 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 5.228695e-05 | 4.282 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 5.228695e-05 | 4.282 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 6.286763e-05 | 4.202 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 6.334765e-05 | 4.198 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 6.630548e-05 | 4.178 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 6.611932e-05 | 4.180 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 7.169334e-05 | 4.145 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 7.416527e-05 | 4.130 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 8.489419e-05 | 4.071 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 8.541483e-05 | 4.068 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 9.780771e-05 | 4.010 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.037509e-04 | 3.984 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.212284e-04 | 3.916 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 1.290110e-04 | 3.889 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.634231e-04 | 3.787 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.798315e-04 | 3.745 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.985992e-04 | 3.702 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.971244e-04 | 3.705 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 2.477916e-04 | 3.606 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 2.755022e-04 | 3.560 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 2.714739e-04 | 3.566 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.783291e-04 | 3.555 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 3.215018e-04 | 3.493 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 3.221992e-04 | 3.492 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 3.624784e-04 | 3.441 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 4.227269e-04 | 3.374 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 4.308174e-04 | 3.366 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 4.508975e-04 | 3.346 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.438045e-04 | 3.265 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 6.140119e-04 | 3.212 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 6.497812e-04 | 3.187 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 7.639235e-04 | 3.117 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 8.019453e-04 | 3.096 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 8.357693e-04 | 3.078 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 8.808413e-04 | 3.055 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 9.507778e-04 | 3.022 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.000269e-03 | 3.000 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 9.620943e-04 | 3.017 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 9.980155e-04 | 3.001 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.120474e-03 | 2.951 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.287607e-03 | 2.890 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 1.296096e-03 | 2.887 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 1.332873e-03 | 2.875 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.386486e-03 | 2.858 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.631708e-03 | 2.787 | 1 | 1 |
| Oncogene Induced Senescence | R-HSA-2559585 | 1.662782e-03 | 2.779 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 1.961357e-03 | 2.707 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.977878e-03 | 2.704 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.978260e-03 | 2.704 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 2.007263e-03 | 2.697 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 2.261480e-03 | 2.646 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 2.272177e-03 | 2.644 | 1 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.197533e-03 | 2.658 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 2.380212e-03 | 2.623 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 2.389218e-03 | 2.622 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 2.421707e-03 | 2.616 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.509479e-03 | 2.600 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 2.623518e-03 | 2.581 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.851758e-03 | 2.545 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 2.884587e-03 | 2.540 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 3.209873e-03 | 2.494 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 3.253578e-03 | 2.488 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.296081e-03 | 2.482 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 3.507012e-03 | 2.455 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 3.659834e-03 | 2.437 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 3.796308e-03 | 2.421 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.973224e-03 | 2.401 | 1 | 1 |
| Signaling by RAS mutants | R-HSA-6802949 | 4.234853e-03 | 2.373 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 4.234853e-03 | 2.373 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 4.234853e-03 | 2.373 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 4.234853e-03 | 2.373 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 4.088869e-03 | 2.388 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 4.183086e-03 | 2.379 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 4.792503e-03 | 2.319 | 1 | 1 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 4.792503e-03 | 2.319 | 1 | 1 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 4.672961e-03 | 2.330 | 1 | 1 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 4.642581e-03 | 2.333 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 4.792503e-03 | 2.319 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 4.781148e-03 | 2.320 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 5.167332e-03 | 2.287 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 5.858643e-03 | 2.232 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 5.858643e-03 | 2.232 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 5.858643e-03 | 2.232 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 5.858643e-03 | 2.232 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 5.796288e-03 | 2.237 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 5.796288e-03 | 2.237 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 5.796288e-03 | 2.237 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 5.646476e-03 | 2.248 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 5.371834e-03 | 2.270 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 6.036373e-03 | 2.219 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 5.446064e-03 | 2.264 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.155906e-03 | 2.211 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 6.174291e-03 | 2.209 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 6.204509e-03 | 2.207 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 6.567731e-03 | 2.183 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 6.802616e-03 | 2.167 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 6.982433e-03 | 2.156 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 7.202903e-03 | 2.142 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 7.414740e-03 | 2.130 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 7.414740e-03 | 2.130 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 8.357608e-03 | 2.078 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 8.357608e-03 | 2.078 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 8.357608e-03 | 2.078 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 8.357608e-03 | 2.078 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 8.357608e-03 | 2.078 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 8.357608e-03 | 2.078 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 7.913516e-03 | 2.102 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 7.925729e-03 | 2.101 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 8.734468e-03 | 2.059 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 8.793685e-03 | 2.056 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 9.034515e-03 | 2.044 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 9.034515e-03 | 2.044 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 9.347187e-03 | 2.029 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 9.663838e-03 | 2.015 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 9.663838e-03 | 2.015 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 9.893641e-03 | 2.005 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 1.089409e-02 | 1.963 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.094522e-02 | 1.961 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.111053e-02 | 1.954 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.141946e-02 | 1.942 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.156841e-02 | 1.937 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.163487e-02 | 1.934 | 1 | 1 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.316675e-02 | 1.881 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.316675e-02 | 1.881 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.316675e-02 | 1.881 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.316675e-02 | 1.881 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 1.235802e-02 | 1.908 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.290804e-02 | 1.889 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.197707e-02 | 1.922 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.272749e-02 | 1.895 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 1.272749e-02 | 1.895 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.316675e-02 | 1.881 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.290804e-02 | 1.889 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.320094e-02 | 1.879 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.389313e-02 | 1.857 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.413624e-02 | 1.850 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 1.420310e-02 | 1.848 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 1.432608e-02 | 1.844 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 1.452403e-02 | 1.838 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 1.454309e-02 | 1.837 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 1.478397e-02 | 1.830 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.544999e-02 | 1.811 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.599554e-02 | 1.796 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.604062e-02 | 1.795 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 1.658671e-02 | 1.780 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 2.090373e-02 | 1.680 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.941329e-02 | 1.712 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 2.052475e-02 | 1.688 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.941329e-02 | 1.712 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.941329e-02 | 1.712 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 2.109356e-02 | 1.676 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.110795e-02 | 1.676 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 2.110795e-02 | 1.676 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 2.161163e-02 | 1.665 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 2.244632e-02 | 1.649 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 2.258769e-02 | 1.646 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 2.258769e-02 | 1.646 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 2.258769e-02 | 1.646 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 2.273318e-02 | 1.643 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 2.273318e-02 | 1.643 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 2.277056e-02 | 1.643 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 2.343158e-02 | 1.630 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 2.363021e-02 | 1.627 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 2.371310e-02 | 1.625 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.380086e-02 | 1.623 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 2.380086e-02 | 1.623 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 2.382881e-02 | 1.623 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 2.599831e-02 | 1.585 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 2.485071e-02 | 1.605 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.475420e-02 | 1.606 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 2.598008e-02 | 1.585 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 2.493032e-02 | 1.603 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 2.673006e-02 | 1.573 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.444728e-02 | 1.612 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.742641e-02 | 1.562 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.771806e-02 | 1.557 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.841513e-02 | 1.546 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 2.861446e-02 | 1.543 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 2.861446e-02 | 1.543 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 2.861446e-02 | 1.543 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 2.907811e-02 | 1.536 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 2.921325e-02 | 1.534 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 2.927141e-02 | 1.534 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 3.012816e-02 | 1.521 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.029826e-02 | 1.519 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 3.294574e-02 | 1.482 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 3.302071e-02 | 1.481 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 3.353176e-02 | 1.475 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 3.353176e-02 | 1.475 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 3.460642e-02 | 1.461 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 3.460642e-02 | 1.461 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 3.502498e-02 | 1.456 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 3.657146e-02 | 1.437 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 3.567484e-02 | 1.448 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 3.862533e-02 | 1.413 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 3.759810e-02 | 1.425 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 3.561136e-02 | 1.448 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 3.958120e-02 | 1.403 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 3.859372e-02 | 1.413 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 3.636453e-02 | 1.439 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 3.636453e-02 | 1.439 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 3.859372e-02 | 1.413 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 4.017448e-02 | 1.396 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 4.028542e-02 | 1.395 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 4.042702e-02 | 1.393 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 4.104249e-02 | 1.387 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 4.105458e-02 | 1.387 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 4.115406e-02 | 1.386 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 4.259901e-02 | 1.371 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 4.361622e-02 | 1.360 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 4.361622e-02 | 1.360 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 4.477061e-02 | 1.349 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 4.477339e-02 | 1.349 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 4.479162e-02 | 1.349 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 4.496557e-02 | 1.347 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 4.496557e-02 | 1.347 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 4.496557e-02 | 1.347 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 4.915138e-02 | 1.308 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 4.915138e-02 | 1.308 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 4.915138e-02 | 1.308 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 4.915138e-02 | 1.308 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 4.915138e-02 | 1.308 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 4.915138e-02 | 1.308 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 4.915138e-02 | 1.308 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 4.699649e-02 | 1.328 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 4.699649e-02 | 1.328 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 4.699649e-02 | 1.328 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 5.194017e-02 | 1.284 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 5.390173e-02 | 1.268 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 4.938245e-02 | 1.306 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 4.938245e-02 | 1.306 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 5.334674e-02 | 1.273 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 5.334674e-02 | 1.273 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 4.705843e-02 | 1.327 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.722113e-02 | 1.326 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 5.390173e-02 | 1.268 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 5.390173e-02 | 1.268 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 4.938245e-02 | 1.306 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 5.131271e-02 | 1.290 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 5.131271e-02 | 1.290 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 4.910950e-02 | 1.309 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 5.414972e-02 | 1.266 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 5.422227e-02 | 1.266 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 5.457933e-02 | 1.263 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 5.457933e-02 | 1.263 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 5.493506e-02 | 1.260 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 5.539098e-02 | 1.257 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.617475e-02 | 1.250 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 5.681116e-02 | 1.246 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 5.734136e-02 | 1.242 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 5.758314e-02 | 1.240 | 1 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 5.786963e-02 | 1.238 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 5.814543e-02 | 1.235 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 5.844702e-02 | 1.233 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 5.883090e-02 | 1.230 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 5.884856e-02 | 1.230 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 5.956987e-02 | 1.225 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 6.091192e-02 | 1.215 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 6.112654e-02 | 1.214 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 6.157881e-02 | 1.211 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 6.324319e-02 | 1.199 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 6.324319e-02 | 1.199 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 6.324319e-02 | 1.199 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 6.324319e-02 | 1.199 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 6.331411e-02 | 1.198 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 6.390249e-02 | 1.194 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 6.390249e-02 | 1.194 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 6.429169e-02 | 1.192 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 6.544519e-02 | 1.184 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 6.640741e-02 | 1.178 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 6.640741e-02 | 1.178 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 6.640741e-02 | 1.178 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 6.670815e-02 | 1.176 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 6.726862e-02 | 1.172 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 7.656020e-02 | 1.116 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 7.656020e-02 | 1.116 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 7.656020e-02 | 1.116 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 8.226204e-02 | 1.085 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 8.226204e-02 | 1.085 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 8.131044e-02 | 1.090 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 7.840684e-02 | 1.106 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 7.112072e-02 | 1.148 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 7.112072e-02 | 1.148 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 7.746794e-02 | 1.111 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 7.877929e-02 | 1.104 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 7.927865e-02 | 1.101 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 7.279969e-02 | 1.138 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 7.856281e-02 | 1.105 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 7.370824e-02 | 1.132 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 7.559074e-02 | 1.122 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 7.328162e-02 | 1.135 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 7.759948e-02 | 1.110 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 7.579871e-02 | 1.120 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 7.656020e-02 | 1.116 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 7.130822e-02 | 1.147 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 8.298627e-02 | 1.081 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 8.299364e-02 | 1.081 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 8.597246e-02 | 1.066 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 8.747281e-02 | 1.058 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 8.747281e-02 | 1.058 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 8.887405e-02 | 1.051 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 8.887405e-02 | 1.051 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 8.887405e-02 | 1.051 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 9.016986e-02 | 1.045 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 9.084161e-02 | 1.042 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 9.084161e-02 | 1.042 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 9.084161e-02 | 1.042 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 9.084161e-02 | 1.042 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 9.121302e-02 | 1.040 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 9.282626e-02 | 1.032 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 9.632568e-02 | 1.016 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 9.760919e-02 | 1.011 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 9.760919e-02 | 1.011 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 9.760919e-02 | 1.011 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.829378e-02 | 1.007 | 0 | 0 |
| Defective Base Excision Repair Associated with OGG1 | R-HSA-9656249 | 9.878991e-02 | 1.005 | 0 | 0 |
| Transport of glycerol from adipocytes to the liver by Aquaporins | R-HSA-432030 | 9.878991e-02 | 1.005 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 9.878991e-02 | 1.005 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 9.878991e-02 | 1.005 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 9.878991e-02 | 1.005 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 9.878991e-02 | 1.005 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 9.878991e-02 | 1.005 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 9.878991e-02 | 1.005 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 9.878991e-02 | 1.005 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 9.878991e-02 | 1.005 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 9.907564e-02 | 1.004 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 9.907564e-02 | 1.004 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 1.022954e-01 | 0.990 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.022954e-01 | 0.990 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.022954e-01 | 0.990 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 1.039627e-01 | 0.983 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 1.016630e-01 | 0.993 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.223366e-01 | 0.912 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.223366e-01 | 0.912 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.223366e-01 | 0.912 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 1.223366e-01 | 0.912 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.017220e-01 | 0.993 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 1.257552e-01 | 0.900 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 1.257552e-01 | 0.900 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 1.169457e-01 | 0.932 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.087281e-01 | 0.964 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.010957e-01 | 0.995 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.233759e-01 | 0.909 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.233759e-01 | 0.909 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.142592e-01 | 0.942 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 1.186406e-01 | 0.926 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.212534e-01 | 0.916 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.155668e-01 | 0.937 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.096756e-01 | 0.960 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.087945e-01 | 0.963 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 1.214132e-01 | 0.916 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 1.155668e-01 | 0.937 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.169457e-01 | 0.932 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 1.142592e-01 | 0.942 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 1.069008e-01 | 0.971 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 1.155668e-01 | 0.937 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.220092e-01 | 0.914 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.017217e-01 | 0.993 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 1.027578e-01 | 0.988 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.142592e-01 | 0.942 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 1.223366e-01 | 0.912 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.019615e-01 | 0.992 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.186406e-01 | 0.926 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.171954e-01 | 0.931 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 1.039627e-01 | 0.983 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.028106e-01 | 0.988 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.269987e-01 | 0.896 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.269987e-01 | 0.896 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 1.274760e-01 | 0.895 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 1.274760e-01 | 0.895 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.274760e-01 | 0.895 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 1.274760e-01 | 0.895 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.281851e-01 | 0.892 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.286581e-01 | 0.891 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.313040e-01 | 0.882 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 1.314379e-01 | 0.881 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 1.314379e-01 | 0.881 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.319835e-01 | 0.879 | 0 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 1.613799e-01 | 0.792 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 1.613799e-01 | 0.792 | 0 | 0 |
| Defective OGG1 Localization | R-HSA-9657050 | 1.613799e-01 | 0.792 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.613799e-01 | 0.792 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 1.613799e-01 | 0.792 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 1.613799e-01 | 0.792 | 0 | 0 |
| Deletions in the AXIN1 gene destabilize the destruction complex | R-HSA-5467345 | 1.613799e-01 | 0.792 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 1.613799e-01 | 0.792 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 1.613799e-01 | 0.792 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.613799e-01 | 0.792 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 1.613799e-01 | 0.792 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 1.613799e-01 | 0.792 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 1.613799e-01 | 0.792 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 1.613799e-01 | 0.792 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 1.613799e-01 | 0.792 | 0 | 0 |
| Defective OGG1 Substrate Binding | R-HSA-9656255 | 1.613799e-01 | 0.792 | 0 | 0 |
| Deletions in the AMER1 gene destabilize the destruction complex | R-HSA-5467343 | 1.613799e-01 | 0.792 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 1.571727e-01 | 0.804 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 1.571727e-01 | 0.804 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 1.571727e-01 | 0.804 | 0 | 0 |
| Defective OGG1 Substrate Processing | R-HSA-9656256 | 2.967241e-01 | 0.528 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.967241e-01 | 0.528 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 2.967241e-01 | 0.528 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 2.967241e-01 | 0.528 | 0 | 0 |
| Blockage of phagosome acidification | R-HSA-9636467 | 2.967241e-01 | 0.528 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.967241e-01 | 0.528 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 2.967241e-01 | 0.528 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.967241e-01 | 0.528 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 2.967241e-01 | 0.528 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 2.967241e-01 | 0.528 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.967241e-01 | 0.528 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 2.201868e-01 | 0.657 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 2.201868e-01 | 0.657 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 2.201868e-01 | 0.657 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.683878e-01 | 0.774 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 1.683878e-01 | 0.774 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 1.683878e-01 | 0.774 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.683878e-01 | 0.774 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 1.683878e-01 | 0.774 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 1.683878e-01 | 0.774 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 1.635501e-01 | 0.786 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.635501e-01 | 0.786 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 2.124667e-01 | 0.673 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.124667e-01 | 0.673 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 2.124667e-01 | 0.673 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 2.848182e-01 | 0.545 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 2.848182e-01 | 0.545 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 2.848182e-01 | 0.545 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 2.848182e-01 | 0.545 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 2.848182e-01 | 0.545 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 2.848182e-01 | 0.545 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 2.848182e-01 | 0.545 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 2.848182e-01 | 0.545 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 2.848182e-01 | 0.545 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 2.848182e-01 | 0.545 | 0 | 0 |
| PI and PC transport between ER and Golgi membranes | R-HSA-1483196 | 4.102316e-01 | 0.387 | 0 | 0 |
| Nef mediated downregulation of CD28 cell surface expression | R-HSA-164939 | 4.102316e-01 | 0.387 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 4.102316e-01 | 0.387 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 4.102316e-01 | 0.387 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 4.102316e-01 | 0.387 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 4.102316e-01 | 0.387 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5660686 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective SLC12A3 causes Gitelman syndrome (GS) | R-HSA-5619087 | 4.102316e-01 | 0.387 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 4.102316e-01 | 0.387 | 0 | 0 |
| MyD88 deficiency (TLR5) | R-HSA-5602680 | 4.102316e-01 | 0.387 | 0 | 0 |
| MPS IIID - Sanfilippo syndrome D | R-HSA-2206305 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 4.102316e-01 | 0.387 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 4.102316e-01 | 0.387 | 0 | 0 |
| Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) | R-HSA-5619101 | 4.102316e-01 | 0.387 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 4.102316e-01 | 0.387 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5660724 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective CD320 causes MMATC | R-HSA-3359485 | 4.102316e-01 | 0.387 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5619081 | 4.102316e-01 | 0.387 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.547120e-01 | 0.810 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.547120e-01 | 0.810 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.547120e-01 | 0.810 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 1.547120e-01 | 0.810 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 1.547120e-01 | 0.810 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 1.547120e-01 | 0.810 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 1.981385e-01 | 0.703 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 1.981385e-01 | 0.703 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 2.586520e-01 | 0.587 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.586520e-01 | 0.587 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 2.586520e-01 | 0.587 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 2.586520e-01 | 0.587 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.586520e-01 | 0.587 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 2.586520e-01 | 0.587 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 1.832824e-01 | 0.737 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.832824e-01 | 0.737 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 1.832824e-01 | 0.737 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 1.832824e-01 | 0.737 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 1.832824e-01 | 0.737 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 1.351187e-01 | 0.869 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 1.691954e-01 | 0.772 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 1.691954e-01 | 0.772 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 1.691954e-01 | 0.772 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 2.346837e-01 | 0.630 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 2.346837e-01 | 0.630 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 3.489046e-01 | 0.457 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 3.489046e-01 | 0.457 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 3.489046e-01 | 0.457 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 3.489046e-01 | 0.457 | 0 | 0 |
| IRS activation | R-HSA-74713 | 3.489046e-01 | 0.457 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 3.489046e-01 | 0.457 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 3.489046e-01 | 0.457 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 3.489046e-01 | 0.457 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 3.489046e-01 | 0.457 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 3.489046e-01 | 0.457 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 1.561764e-01 | 0.806 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 1.561764e-01 | 0.806 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 1.561764e-01 | 0.806 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 1.561764e-01 | 0.806 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 2.136041e-01 | 0.670 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.136041e-01 | 0.670 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 2.136041e-01 | 0.670 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 1.950548e-01 | 0.710 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 3.059771e-01 | 0.514 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 3.059771e-01 | 0.514 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 3.059771e-01 | 0.514 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 1.786298e-01 | 0.748 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 1.786298e-01 | 0.748 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 1.786298e-01 | 0.748 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 1.786298e-01 | 0.748 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 2.726642e-01 | 0.564 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 2.726642e-01 | 0.564 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 2.726642e-01 | 0.564 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 2.726642e-01 | 0.564 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 1.508681e-01 | 0.821 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 1.508681e-01 | 0.821 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 2.453663e-01 | 0.610 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 2.453663e-01 | 0.610 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 2.453663e-01 | 0.610 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 2.453663e-01 | 0.610 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.453663e-01 | 0.610 | 0 | 0 |
| PKA activation | R-HSA-163615 | 2.222794e-01 | 0.653 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 2.222794e-01 | 0.653 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 2.023515e-01 | 0.694 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.849042e-01 | 0.733 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.557027e-01 | 0.808 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.557027e-01 | 0.808 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.433488e-01 | 0.844 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.322054e-01 | 0.879 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.592228e-01 | 0.798 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 1.890764e-01 | 0.723 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 1.890764e-01 | 0.723 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 2.506592e-01 | 0.601 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 3.115755e-01 | 0.506 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 3.115755e-01 | 0.506 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 3.115755e-01 | 0.506 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 3.535934e-01 | 0.451 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 3.535934e-01 | 0.451 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 3.535934e-01 | 0.451 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 3.535934e-01 | 0.451 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 3.535934e-01 | 0.451 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 4.109390e-01 | 0.386 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 4.109390e-01 | 0.386 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 4.109390e-01 | 0.386 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 4.109390e-01 | 0.386 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 4.109390e-01 | 0.386 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 4.109390e-01 | 0.386 | 0 | 0 |
| Phase 1 - inactivation of fast Na+ channels | R-HSA-5576894 | 4.109390e-01 | 0.386 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 5.054246e-01 | 0.296 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 5.054246e-01 | 0.296 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective UGT1A4 causes hyperbilirubinemia | R-HSA-5579016 | 5.054246e-01 | 0.296 | 0 | 0 |
| Interaction between PHLDA1 and AURKA | R-HSA-8854521 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 5.054246e-01 | 0.296 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 5.054246e-01 | 0.296 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 5.054246e-01 | 0.296 | 0 | 0 |
| Signaling by RAS GAP mutants | R-HSA-9753510 | 5.054246e-01 | 0.296 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective SLC12A1 causes Bartter syndrome 1 (BS1) | R-HSA-5619104 | 5.054246e-01 | 0.296 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective DHDDS causes RP59 | R-HSA-4755609 | 5.054246e-01 | 0.296 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective visual phototransduction due to STRA6 loss of function | R-HSA-9918449 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 5.054246e-01 | 0.296 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.759355e-01 | 0.755 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 2.096156e-01 | 0.679 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 2.298386e-01 | 0.639 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 1.391728e-01 | 0.856 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 2.799762e-01 | 0.553 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.404274e-01 | 0.853 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 3.119379e-01 | 0.506 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 1.787345e-01 | 0.748 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 3.509445e-01 | 0.455 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 3.509445e-01 | 0.455 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 2.796575e-01 | 0.553 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.311646e-01 | 0.636 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 2.531418e-01 | 0.597 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 4.007799e-01 | 0.397 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 4.007799e-01 | 0.397 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 4.007799e-01 | 0.397 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 4.007799e-01 | 0.397 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.781582e-01 | 0.556 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 2.781582e-01 | 0.556 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 2.781582e-01 | 0.556 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 3.069444e-01 | 0.513 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 2.759401e-01 | 0.559 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.281918e-01 | 0.642 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.090408e-01 | 0.680 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.090408e-01 | 0.680 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 1.909713e-01 | 0.719 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 3.405410e-01 | 0.468 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 4.699148e-01 | 0.328 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 4.699148e-01 | 0.328 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 4.699148e-01 | 0.328 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.992955e-01 | 0.524 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 2.433345e-01 | 0.614 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 3.347179e-01 | 0.475 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 2.951479e-01 | 0.530 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.681609e-01 | 0.774 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.713578e-01 | 0.430 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 4.469430e-01 | 0.350 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 4.469430e-01 | 0.350 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 3.174622e-01 | 0.498 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 3.174622e-01 | 0.498 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 2.472482e-01 | 0.607 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 2.439548e-01 | 0.613 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 3.548079e-01 | 0.450 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 4.293731e-01 | 0.367 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.293731e-01 | 0.367 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 4.293731e-01 | 0.367 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 4.293731e-01 | 0.367 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 4.293731e-01 | 0.367 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.535666e-01 | 0.814 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.385818e-01 | 0.858 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.510262e-01 | 0.600 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 2.474252e-01 | 0.607 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 4.022574e-01 | 0.395 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 3.716705e-01 | 0.430 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 3.550094e-01 | 0.450 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 2.791047e-01 | 0.554 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 2.259527e-01 | 0.646 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 3.136157e-01 | 0.504 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 3.682098e-01 | 0.434 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 3.861670e-01 | 0.413 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 3.861670e-01 | 0.413 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 4.193621e-01 | 0.377 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 4.193621e-01 | 0.377 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 4.330494e-01 | 0.363 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 4.488376e-01 | 0.348 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 4.677121e-01 | 0.330 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 4.916097e-01 | 0.308 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 5.252036e-01 | 0.280 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 5.252036e-01 | 0.280 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 5.252036e-01 | 0.280 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 5.252036e-01 | 0.280 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 5.252036e-01 | 0.280 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 5.252036e-01 | 0.280 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 5.252036e-01 | 0.280 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 5.252036e-01 | 0.280 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 2.055106e-01 | 0.687 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 3.658680e-01 | 0.437 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 3.737253e-01 | 0.427 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 4.334280e-01 | 0.363 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 3.908020e-01 | 0.408 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 4.475166e-01 | 0.349 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 4.635581e-01 | 0.334 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 4.635581e-01 | 0.334 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 3.030764e-01 | 0.518 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 4.823070e-01 | 0.317 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 4.823070e-01 | 0.317 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 4.203052e-01 | 0.376 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 4.311979e-01 | 0.365 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 5.050715e-01 | 0.297 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 5.050715e-01 | 0.297 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 4.697734e-01 | 0.328 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 4.936236e-01 | 0.307 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 4.787480e-01 | 0.320 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 5.150458e-01 | 0.288 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 3.889261e-01 | 0.410 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 4.806319e-01 | 0.318 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 4.215075e-01 | 0.375 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 4.752978e-01 | 0.323 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 5.231030e-01 | 0.281 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 4.826554e-01 | 0.316 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 4.997174e-01 | 0.301 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 4.979252e-01 | 0.303 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 4.979252e-01 | 0.303 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 5.187215e-01 | 0.285 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 2.554593e-01 | 0.593 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.806394e-01 | 0.743 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 3.032799e-01 | 0.518 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 5.174686e-01 | 0.286 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 4.979252e-01 | 0.303 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 4.823070e-01 | 0.317 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 1.948977e-01 | 0.710 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 2.191305e-01 | 0.659 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 3.768716e-01 | 0.424 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.539150e-01 | 0.595 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 3.583979e-01 | 0.446 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 2.068894e-01 | 0.684 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 2.271996e-01 | 0.644 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 4.093710e-01 | 0.388 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 4.263604e-01 | 0.370 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 3.415842e-01 | 0.467 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 2.726642e-01 | 0.564 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 4.632471e-01 | 0.334 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 2.782500e-01 | 0.556 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 4.148317e-01 | 0.382 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 2.191305e-01 | 0.659 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.133936e-01 | 0.671 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 3.100097e-01 | 0.509 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 4.007799e-01 | 0.397 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.604989e-01 | 0.795 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 1.917858e-01 | 0.717 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 4.101475e-01 | 0.387 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 1.333421e-01 | 0.875 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 1.390461e-01 | 0.857 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 2.782500e-01 | 0.556 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 3.115755e-01 | 0.506 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.414805e-01 | 0.849 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 3.768716e-01 | 0.424 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 4.936236e-01 | 0.307 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 4.557387e-01 | 0.341 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 3.630578e-01 | 0.440 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 1.694684e-01 | 0.771 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 1.433488e-01 | 0.844 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 2.280929e-01 | 0.642 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 4.867371e-01 | 0.313 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 2.726642e-01 | 0.564 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 2.440382e-01 | 0.613 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 3.020922e-01 | 0.520 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 2.726642e-01 | 0.564 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 3.100097e-01 | 0.509 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 4.007799e-01 | 0.397 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.362414e-01 | 0.866 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 4.697734e-01 | 0.328 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 4.015654e-01 | 0.396 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.489908e-01 | 0.827 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 2.742012e-01 | 0.562 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 3.174622e-01 | 0.498 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 1.403549e-01 | 0.853 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 4.293731e-01 | 0.367 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.779769e-01 | 0.750 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 2.866960e-01 | 0.543 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 3.835942e-01 | 0.416 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 2.453663e-01 | 0.610 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 1.849042e-01 | 0.733 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.374589e-01 | 0.862 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 2.531418e-01 | 0.597 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.939394e-01 | 0.712 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 3.962215e-01 | 0.402 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 2.782500e-01 | 0.556 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 2.116415e-01 | 0.674 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 2.116415e-01 | 0.674 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.544832e-01 | 0.811 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.820763e-01 | 0.740 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 3.288725e-01 | 0.483 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 4.488376e-01 | 0.348 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 4.209139e-01 | 0.376 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 4.209139e-01 | 0.376 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 2.137139e-01 | 0.670 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 4.938233e-01 | 0.306 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 4.585074e-01 | 0.339 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.683878e-01 | 0.774 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 2.848182e-01 | 0.545 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.981385e-01 | 0.703 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 1.832824e-01 | 0.737 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 2.453663e-01 | 0.610 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 2.023515e-01 | 0.694 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 2.271996e-01 | 0.644 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 2.310013e-01 | 0.636 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 2.246515e-01 | 0.648 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 2.458130e-01 | 0.609 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 3.347179e-01 | 0.475 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 2.205034e-01 | 0.657 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 4.293731e-01 | 0.367 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 2.690189e-01 | 0.570 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 5.252036e-01 | 0.280 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 4.001500e-01 | 0.398 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 4.078986e-01 | 0.389 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 4.939556e-01 | 0.306 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 1.779769e-01 | 0.750 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 3.629323e-01 | 0.440 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 3.688552e-01 | 0.433 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 1.917858e-01 | 0.717 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 2.531418e-01 | 0.597 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 2.519156e-01 | 0.599 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 4.072060e-01 | 0.390 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 3.487029e-01 | 0.458 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 5.108674e-01 | 0.292 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 4.006241e-01 | 0.397 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 4.322798e-01 | 0.364 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 1.448973e-01 | 0.839 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 1.448973e-01 | 0.839 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 1.917858e-01 | 0.717 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 4.566754e-01 | 0.340 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 2.501916e-01 | 0.602 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.105914e-01 | 0.677 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 4.681416e-01 | 0.330 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.981385e-01 | 0.703 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 1.779769e-01 | 0.750 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 4.072060e-01 | 0.390 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 3.377385e-01 | 0.471 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 2.220702e-01 | 0.654 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.974920e-01 | 0.527 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 3.147445e-01 | 0.502 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 4.469430e-01 | 0.350 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 2.124667e-01 | 0.673 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 3.059771e-01 | 0.514 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 2.726642e-01 | 0.564 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.271996e-01 | 0.644 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 3.115755e-01 | 0.506 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 2.096156e-01 | 0.679 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 3.119379e-01 | 0.506 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 3.401276e-01 | 0.468 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 3.809600e-01 | 0.419 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 4.677121e-01 | 0.330 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 5.050715e-01 | 0.297 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 4.001794e-01 | 0.398 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 4.853597e-01 | 0.314 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.460340e-01 | 0.836 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 3.915513e-01 | 0.407 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 3.915513e-01 | 0.407 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.874255e-01 | 0.727 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 2.093976e-01 | 0.679 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.503190e-01 | 0.823 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 1.888032e-01 | 0.724 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 5.255136e-01 | 0.279 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.639909e-01 | 0.785 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 3.805107e-01 | 0.420 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 1.786167e-01 | 0.748 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 3.694760e-01 | 0.432 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 1.888032e-01 | 0.724 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 2.068894e-01 | 0.684 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 4.619553e-01 | 0.335 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 1.547120e-01 | 0.810 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 3.149292e-01 | 0.502 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 3.600867e-01 | 0.444 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.759355e-01 | 0.755 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.506296e-01 | 0.822 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 2.531418e-01 | 0.597 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 4.786784e-01 | 0.320 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 2.748710e-01 | 0.561 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 3.289346e-01 | 0.483 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 4.786784e-01 | 0.320 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 4.615071e-01 | 0.336 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 1.683878e-01 | 0.774 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 1.683878e-01 | 0.774 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 3.489046e-01 | 0.457 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 1.733006e-01 | 0.761 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 2.506592e-01 | 0.601 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 3.535934e-01 | 0.451 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 3.535934e-01 | 0.451 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 3.509445e-01 | 0.455 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 2.519156e-01 | 0.599 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 2.909293e-01 | 0.536 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 3.148034e-01 | 0.502 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 3.148034e-01 | 0.502 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 3.148034e-01 | 0.502 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 3.148034e-01 | 0.502 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 4.677121e-01 | 0.330 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 4.916097e-01 | 0.308 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 4.475166e-01 | 0.349 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 5.178329e-01 | 0.286 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 5.221846e-01 | 0.282 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 3.861670e-01 | 0.413 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 5.221846e-01 | 0.282 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.635173e-01 | 0.786 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 3.685077e-01 | 0.434 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 2.933045e-01 | 0.533 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 2.909293e-01 | 0.536 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 3.174622e-01 | 0.498 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 3.174622e-01 | 0.498 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 3.685077e-01 | 0.434 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 5.050715e-01 | 0.297 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 3.119379e-01 | 0.506 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 4.595142e-01 | 0.338 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 3.685077e-01 | 0.434 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 2.501448e-01 | 0.602 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 2.586520e-01 | 0.587 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 4.330494e-01 | 0.363 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 4.883620e-01 | 0.311 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 1.649967e-01 | 0.783 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 2.963927e-01 | 0.528 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 2.530684e-01 | 0.597 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 1.905273e-01 | 0.720 | 1 | 0 |
| Immune System | R-HSA-168256 | 4.202097e-01 | 0.377 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.453663e-01 | 0.610 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 4.007799e-01 | 0.397 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.065892e-01 | 0.295 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 5.286039e-01 | 0.277 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 5.203253e-01 | 0.284 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 3.036056e-01 | 0.518 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.530215e-01 | 0.597 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.981385e-01 | 0.703 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 3.489046e-01 | 0.457 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 3.059771e-01 | 0.514 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.023515e-01 | 0.694 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 3.831265e-01 | 0.417 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.353363e-01 | 0.628 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.231049e-01 | 0.491 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 4.697734e-01 | 0.328 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.293731e-01 | 0.367 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 3.883595e-01 | 0.411 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 1.950548e-01 | 0.710 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 1.791590e-01 | 0.747 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 4.006241e-01 | 0.397 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 1.351187e-01 | 0.869 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.776760e-01 | 0.750 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 2.298386e-01 | 0.639 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.433488e-01 | 0.844 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.938233e-01 | 0.306 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.525164e-01 | 0.817 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.967241e-01 | 0.528 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 2.967241e-01 | 0.528 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 2.848182e-01 | 0.545 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 4.102316e-01 | 0.387 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 4.102316e-01 | 0.387 | 0 | 0 |
| Inhibition of Host mRNA Processing and RNA Silencing | R-HSA-168315 | 4.102316e-01 | 0.387 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 4.102316e-01 | 0.387 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 1.832824e-01 | 0.737 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 3.489046e-01 | 0.457 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 3.489046e-01 | 0.457 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 2.453663e-01 | 0.610 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 1.322054e-01 | 0.879 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 4.109390e-01 | 0.386 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 5.054246e-01 | 0.296 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 5.054246e-01 | 0.296 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 5.054246e-01 | 0.296 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 5.054246e-01 | 0.296 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 1.917858e-01 | 0.717 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 1.413041e-01 | 0.850 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 3.509445e-01 | 0.455 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 2.116922e-01 | 0.674 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.946106e-01 | 0.711 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 4.007799e-01 | 0.397 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 2.732708e-01 | 0.563 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 3.805107e-01 | 0.420 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 3.628160e-01 | 0.440 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 2.214985e-01 | 0.655 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 3.333495e-01 | 0.477 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 4.916097e-01 | 0.308 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 4.325879e-01 | 0.364 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 4.823070e-01 | 0.317 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 4.557387e-01 | 0.341 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 1.413041e-01 | 0.850 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.643278e-01 | 0.578 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 3.115755e-01 | 0.506 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 3.148034e-01 | 0.502 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 3.809600e-01 | 0.419 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 2.222794e-01 | 0.653 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 3.464481e-01 | 0.460 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 2.659621e-01 | 0.575 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 3.891335e-01 | 0.410 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 4.754116e-01 | 0.323 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 4.595142e-01 | 0.338 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.977911e-01 | 0.400 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 1.683878e-01 | 0.774 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 2.453663e-01 | 0.610 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 3.535934e-01 | 0.451 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 4.595142e-01 | 0.338 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 4.605970e-01 | 0.337 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 5.041333e-01 | 0.297 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 3.198311e-01 | 0.495 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 3.545125e-01 | 0.450 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 3.405410e-01 | 0.468 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 4.767803e-01 | 0.322 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 1.635173e-01 | 0.786 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 1.733006e-01 | 0.761 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 3.903388e-01 | 0.409 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 3.550094e-01 | 0.450 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 4.677121e-01 | 0.330 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 2.530215e-01 | 0.597 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 2.433345e-01 | 0.614 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 2.586520e-01 | 0.587 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.983905e-01 | 0.525 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 3.694814e-01 | 0.432 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 4.635581e-01 | 0.334 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.293731e-01 | 0.367 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 4.842276e-01 | 0.315 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 4.823070e-01 | 0.317 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 4.102316e-01 | 0.387 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 1.832824e-01 | 0.737 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 3.489046e-01 | 0.457 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 3.535934e-01 | 0.451 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 3.535934e-01 | 0.451 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 2.531418e-01 | 0.597 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 2.732708e-01 | 0.563 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 4.469430e-01 | 0.350 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 5.252036e-01 | 0.280 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 4.101499e-01 | 0.387 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 2.951479e-01 | 0.530 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 2.346837e-01 | 0.630 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 2.136041e-01 | 0.670 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 1.759355e-01 | 0.755 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 4.823070e-01 | 0.317 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 2.298386e-01 | 0.639 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 2.506592e-01 | 0.601 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 3.805107e-01 | 0.420 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 2.510262e-01 | 0.600 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.222794e-01 | 0.653 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 1.981385e-01 | 0.703 | 0 | 0 |
| Diseases of Base Excision Repair | R-HSA-9605308 | 4.109390e-01 | 0.386 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 2.639267e-01 | 0.579 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 1.981385e-01 | 0.703 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 3.489046e-01 | 0.457 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 4.109390e-01 | 0.386 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 3.401276e-01 | 0.468 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 5.150458e-01 | 0.288 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 5.135760e-01 | 0.289 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 2.726914e-01 | 0.564 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 2.406970e-01 | 0.619 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.790305e-01 | 0.554 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 5.124821e-01 | 0.290 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 3.100097e-01 | 0.509 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 3.861670e-01 | 0.413 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 5.252036e-01 | 0.280 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 3.861670e-01 | 0.413 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 4.643391e-01 | 0.333 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 1.917858e-01 | 0.717 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 5.150458e-01 | 0.288 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 4.677121e-01 | 0.330 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.799762e-01 | 0.553 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 5.297173e-01 | 0.276 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 5.299462e-01 | 0.276 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 5.344176e-01 | 0.272 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 5.344176e-01 | 0.272 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 5.344176e-01 | 0.272 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 5.344176e-01 | 0.272 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 5.344176e-01 | 0.272 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 5.344176e-01 | 0.272 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 5.344176e-01 | 0.272 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 5.344176e-01 | 0.272 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 5.396790e-01 | 0.268 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 5.412167e-01 | 0.267 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 5.412167e-01 | 0.267 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 5.412167e-01 | 0.267 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 5.412167e-01 | 0.267 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.442231e-01 | 0.264 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 5.462390e-01 | 0.263 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 5.476116e-01 | 0.262 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 5.484512e-01 | 0.261 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 5.507667e-01 | 0.259 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 5.512356e-01 | 0.259 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 5.518709e-01 | 0.258 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 5.518709e-01 | 0.258 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 5.518709e-01 | 0.258 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 5.518709e-01 | 0.258 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 5.518709e-01 | 0.258 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 5.548306e-01 | 0.256 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 5.549843e-01 | 0.256 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 5.549843e-01 | 0.256 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 5.589431e-01 | 0.253 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 5.605229e-01 | 0.251 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 5.643862e-01 | 0.248 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 5.666462e-01 | 0.247 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 5.714560e-01 | 0.243 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 5.747279e-01 | 0.241 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 5.751025e-01 | 0.240 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 5.751025e-01 | 0.240 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 5.751025e-01 | 0.240 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 5.751025e-01 | 0.240 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 5.751025e-01 | 0.240 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 5.751025e-01 | 0.240 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 5.751025e-01 | 0.240 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 5.759600e-01 | 0.240 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 5.759600e-01 | 0.240 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 5.759600e-01 | 0.240 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 5.764591e-01 | 0.239 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 5.764591e-01 | 0.239 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 5.764591e-01 | 0.239 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 5.764591e-01 | 0.239 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 5.764591e-01 | 0.239 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 5.764591e-01 | 0.239 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 5.764591e-01 | 0.239 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 5.764591e-01 | 0.239 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 5.764591e-01 | 0.239 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 5.764591e-01 | 0.239 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 5.764591e-01 | 0.239 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 5.764591e-01 | 0.239 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 5.764591e-01 | 0.239 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 5.776930e-01 | 0.238 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 5.776930e-01 | 0.238 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 5.798193e-01 | 0.237 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.798193e-01 | 0.237 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 5.798193e-01 | 0.237 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 5.821289e-01 | 0.235 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 5.821289e-01 | 0.235 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 5.845191e-01 | 0.233 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 5.845191e-01 | 0.233 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 5.845191e-01 | 0.233 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 5.852573e-01 | 0.233 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 5.852573e-01 | 0.233 | 0 | 0 |
| Signaling by plasma membrane FGFR1 fusions | R-HSA-8853336 | 5.852573e-01 | 0.233 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 5.852573e-01 | 0.233 | 0 | 0 |
| Activation of Na-permeable kainate receptors | R-HSA-451307 | 5.852573e-01 | 0.233 | 0 | 0 |
| Defective ABCC2 causes DJS | R-HSA-5679001 | 5.852573e-01 | 0.233 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 5.852573e-01 | 0.233 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 5.852573e-01 | 0.233 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 5.852573e-01 | 0.233 | 0 | 0 |
| Adrenaline signalling through Alpha-2 adrenergic receptor | R-HSA-392023 | 5.852573e-01 | 0.233 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 5.852573e-01 | 0.233 | 0 | 0 |
| Defective GCLC causes HAGGSD | R-HSA-5578999 | 5.852573e-01 | 0.233 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 5.852573e-01 | 0.233 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 5.852573e-01 | 0.233 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 5.852573e-01 | 0.233 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 5.852573e-01 | 0.233 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 5.852573e-01 | 0.233 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 5.852573e-01 | 0.233 | 0 | 0 |
| Tachykinin receptors bind tachykinins | R-HSA-380095 | 5.852573e-01 | 0.233 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 5.852573e-01 | 0.233 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 5.852573e-01 | 0.233 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 5.852573e-01 | 0.233 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 5.869356e-01 | 0.231 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 5.882311e-01 | 0.230 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 5.918397e-01 | 0.228 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 5.943758e-01 | 0.226 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 5.987165e-01 | 0.223 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 5.992430e-01 | 0.222 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 5.992430e-01 | 0.222 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 6.068573e-01 | 0.217 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 6.073491e-01 | 0.217 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 6.073491e-01 | 0.217 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 6.073491e-01 | 0.217 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 6.073491e-01 | 0.217 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.074719e-01 | 0.216 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 6.074719e-01 | 0.216 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 6.078749e-01 | 0.216 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 6.087333e-01 | 0.216 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 6.091581e-01 | 0.215 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 6.101842e-01 | 0.215 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 6.134855e-01 | 0.212 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 6.134855e-01 | 0.212 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 6.134855e-01 | 0.212 | 0 | 0 |
| S Phase | R-HSA-69242 | 6.145692e-01 | 0.211 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.213968e-01 | 0.207 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 6.224104e-01 | 0.206 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 6.232595e-01 | 0.205 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 6.235428e-01 | 0.205 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 6.235428e-01 | 0.205 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.235428e-01 | 0.205 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 6.235428e-01 | 0.205 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.235428e-01 | 0.205 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 6.235428e-01 | 0.205 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 6.235428e-01 | 0.205 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 6.235428e-01 | 0.205 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 6.235428e-01 | 0.205 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 6.235428e-01 | 0.205 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 6.235428e-01 | 0.205 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 6.235428e-01 | 0.205 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 6.245009e-01 | 0.204 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 6.324337e-01 | 0.199 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 6.329108e-01 | 0.199 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 6.329108e-01 | 0.199 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 6.329108e-01 | 0.199 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 6.357673e-01 | 0.197 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 6.379206e-01 | 0.195 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 6.407072e-01 | 0.193 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 6.407072e-01 | 0.193 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 6.494601e-01 | 0.187 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 6.494601e-01 | 0.187 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 6.494601e-01 | 0.187 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 6.497888e-01 | 0.187 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 6.501379e-01 | 0.187 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 6.516509e-01 | 0.186 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 6.522074e-01 | 0.186 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 6.522074e-01 | 0.186 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 6.522074e-01 | 0.186 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 6.522074e-01 | 0.186 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 6.522074e-01 | 0.186 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 6.522074e-01 | 0.186 | 0 | 0 |
| MPS VI - Maroteaux-Lamy syndrome | R-HSA-2206285 | 6.522074e-01 | 0.186 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 6.522074e-01 | 0.186 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 6.522074e-01 | 0.186 | 0 | 0 |
| Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate | R-HSA-2978092 | 6.522074e-01 | 0.186 | 0 | 0 |
| Signaling by LRP5 mutants | R-HSA-5339717 | 6.522074e-01 | 0.186 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 6.522074e-01 | 0.186 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 6.522074e-01 | 0.186 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 6.522074e-01 | 0.186 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 6.522074e-01 | 0.186 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 6.522074e-01 | 0.186 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 6.522074e-01 | 0.186 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 6.522074e-01 | 0.186 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 6.546345e-01 | 0.184 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 6.579212e-01 | 0.182 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 6.584538e-01 | 0.181 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 6.628027e-01 | 0.179 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 6.628822e-01 | 0.179 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 6.628822e-01 | 0.179 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 6.639187e-01 | 0.178 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 6.664660e-01 | 0.176 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 6.664660e-01 | 0.176 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 6.664660e-01 | 0.176 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 6.664660e-01 | 0.176 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 6.664660e-01 | 0.176 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 6.664660e-01 | 0.176 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 6.664660e-01 | 0.176 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 6.664660e-01 | 0.176 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 6.680987e-01 | 0.175 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 6.705391e-01 | 0.174 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 6.705391e-01 | 0.174 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 6.705391e-01 | 0.174 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 6.711243e-01 | 0.173 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 6.736061e-01 | 0.172 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 6.818447e-01 | 0.166 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 6.818447e-01 | 0.166 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 6.818447e-01 | 0.166 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 6.823972e-01 | 0.166 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 6.827572e-01 | 0.166 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 6.829802e-01 | 0.166 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 6.829802e-01 | 0.166 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 6.829802e-01 | 0.166 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 6.829802e-01 | 0.166 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 6.829802e-01 | 0.166 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 6.829802e-01 | 0.166 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 6.829802e-01 | 0.166 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 6.829802e-01 | 0.166 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 6.829802e-01 | 0.166 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 6.829802e-01 | 0.166 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 6.829802e-01 | 0.166 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 6.832642e-01 | 0.165 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 6.886490e-01 | 0.162 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 6.886490e-01 | 0.162 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 6.886490e-01 | 0.162 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 6.951098e-01 | 0.158 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 6.978672e-01 | 0.156 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 6.985235e-01 | 0.156 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 6.986172e-01 | 0.156 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 6.986172e-01 | 0.156 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 6.986172e-01 | 0.156 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 7.046513e-01 | 0.152 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 7.046513e-01 | 0.152 | 0 | 0 |
| Presynaptic depolarization and calcium channel opening | R-HSA-112308 | 7.053449e-01 | 0.152 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 7.053449e-01 | 0.152 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 7.053449e-01 | 0.152 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 7.053449e-01 | 0.152 | 0 | 0 |
| Regulation of gene expression in early pancreatic precursor cells | R-HSA-210747 | 7.053449e-01 | 0.152 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 7.053449e-01 | 0.152 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.053449e-01 | 0.152 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.053449e-01 | 0.152 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.053449e-01 | 0.152 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 7.053449e-01 | 0.152 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 7.053449e-01 | 0.152 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 7.057144e-01 | 0.151 | 0 | 0 |
| Activation of AMPA receptors | R-HSA-399710 | 7.083533e-01 | 0.150 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 7.083533e-01 | 0.150 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 7.083533e-01 | 0.150 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 7.083533e-01 | 0.150 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 7.083533e-01 | 0.150 | 0 | 0 |
| Defective SLC1A3 causes episodic ataxia 6 (EA6) | R-HSA-5619062 | 7.083533e-01 | 0.150 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 7.083533e-01 | 0.150 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 7.083533e-01 | 0.150 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 7.083533e-01 | 0.150 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 7.083533e-01 | 0.150 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 7.083533e-01 | 0.150 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 7.083533e-01 | 0.150 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 7.083533e-01 | 0.150 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 7.083533e-01 | 0.150 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 7.092984e-01 | 0.149 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 7.134655e-01 | 0.147 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 7.134655e-01 | 0.147 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 7.134655e-01 | 0.147 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 7.140486e-01 | 0.146 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 7.140486e-01 | 0.146 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 7.140486e-01 | 0.146 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 7.140486e-01 | 0.146 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 7.140486e-01 | 0.146 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 7.144444e-01 | 0.146 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 7.168851e-01 | 0.145 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 7.195911e-01 | 0.143 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 7.207826e-01 | 0.142 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.229170e-01 | 0.141 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 7.249314e-01 | 0.140 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 7.249314e-01 | 0.140 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 7.249314e-01 | 0.140 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 7.249314e-01 | 0.140 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 7.263233e-01 | 0.139 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 7.263233e-01 | 0.139 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 7.323392e-01 | 0.135 | 1 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 7.323392e-01 | 0.135 | 1 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 7.360517e-01 | 0.133 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 7.385917e-01 | 0.132 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 7.403665e-01 | 0.131 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 7.403665e-01 | 0.131 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 7.403665e-01 | 0.131 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 7.403665e-01 | 0.131 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 7.427075e-01 | 0.129 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 7.427075e-01 | 0.129 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 7.427075e-01 | 0.129 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 7.441762e-01 | 0.128 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 7.468541e-01 | 0.127 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 7.468541e-01 | 0.127 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 7.494946e-01 | 0.125 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 7.494946e-01 | 0.125 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 7.494946e-01 | 0.125 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 7.499723e-01 | 0.125 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 7.502931e-01 | 0.125 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 7.552159e-01 | 0.122 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 7.554380e-01 | 0.122 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 7.554380e-01 | 0.122 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 7.554380e-01 | 0.122 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 7.554380e-01 | 0.122 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 7.554380e-01 | 0.122 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 7.554380e-01 | 0.122 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 7.554380e-01 | 0.122 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 7.554380e-01 | 0.122 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 7.554380e-01 | 0.122 | 0 | 0 |
| Formation of the Editosome | R-HSA-75094 | 7.554380e-01 | 0.122 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 7.554380e-01 | 0.122 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 7.554380e-01 | 0.122 | 0 | 0 |
| Sensory perception of salty taste | R-HSA-9730628 | 7.554380e-01 | 0.122 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 7.554380e-01 | 0.122 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 7.554380e-01 | 0.122 | 0 | 0 |
| Ligand-receptor interactions | R-HSA-5632681 | 7.554380e-01 | 0.122 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 7.554380e-01 | 0.122 | 0 | 0 |
| Relaxin receptors | R-HSA-444821 | 7.554380e-01 | 0.122 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 7.554380e-01 | 0.122 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 7.554380e-01 | 0.122 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 7.571679e-01 | 0.121 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 7.571679e-01 | 0.121 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 7.587152e-01 | 0.120 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 7.662473e-01 | 0.116 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 7.667618e-01 | 0.115 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 7.681832e-01 | 0.115 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 7.690290e-01 | 0.114 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 7.690290e-01 | 0.114 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 7.690290e-01 | 0.114 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 7.704842e-01 | 0.113 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 7.704842e-01 | 0.113 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 7.704842e-01 | 0.113 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 7.714970e-01 | 0.113 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 7.717627e-01 | 0.113 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 7.717627e-01 | 0.113 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 7.717627e-01 | 0.113 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 7.723383e-01 | 0.112 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.723383e-01 | 0.112 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 7.733305e-01 | 0.112 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 7.733305e-01 | 0.112 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 7.747743e-01 | 0.111 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 7.763187e-01 | 0.110 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 7.785901e-01 | 0.109 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 7.845150e-01 | 0.105 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.845150e-01 | 0.105 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 7.845150e-01 | 0.105 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 7.849843e-01 | 0.105 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 7.849843e-01 | 0.105 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 7.911093e-01 | 0.102 | 1 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 7.911093e-01 | 0.102 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 7.931080e-01 | 0.101 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 7.931080e-01 | 0.101 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 7.931080e-01 | 0.101 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 7.931080e-01 | 0.101 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 7.931080e-01 | 0.101 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 7.931080e-01 | 0.101 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 7.931080e-01 | 0.101 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 7.931080e-01 | 0.101 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 7.935096e-01 | 0.100 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 7.935096e-01 | 0.100 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 7.935096e-01 | 0.100 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 7.935096e-01 | 0.100 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.935096e-01 | 0.100 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 7.935096e-01 | 0.100 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 7.935096e-01 | 0.100 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 7.935096e-01 | 0.100 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 7.949233e-01 | 0.100 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 7.949233e-01 | 0.100 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 7.949233e-01 | 0.100 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 7.949233e-01 | 0.100 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 7.949233e-01 | 0.100 | 0 | 0 |
| Defective CHST3 causes SEDCJD | R-HSA-3595172 | 7.949233e-01 | 0.100 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 7.949233e-01 | 0.100 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 7.949233e-01 | 0.100 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 7.949233e-01 | 0.100 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 7.949233e-01 | 0.100 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 7.949233e-01 | 0.100 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 7.949233e-01 | 0.100 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 7.949233e-01 | 0.100 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 7.949233e-01 | 0.100 | 0 | 0 |
| Metabolism of vitamin K | R-HSA-6806664 | 7.949233e-01 | 0.100 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 7.949233e-01 | 0.100 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 7.949233e-01 | 0.100 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.983843e-01 | 0.098 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 7.997913e-01 | 0.097 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 7.997913e-01 | 0.097 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 7.997913e-01 | 0.097 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 7.997913e-01 | 0.097 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 8.003971e-01 | 0.097 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 8.130674e-01 | 0.090 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.130674e-01 | 0.090 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 8.130674e-01 | 0.090 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 8.145417e-01 | 0.089 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 8.150556e-01 | 0.089 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 8.150556e-01 | 0.089 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 8.150556e-01 | 0.089 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 8.150556e-01 | 0.089 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 8.150556e-01 | 0.089 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 8.150556e-01 | 0.089 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 8.150556e-01 | 0.089 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 8.177592e-01 | 0.087 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 8.199817e-01 | 0.086 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 8.218973e-01 | 0.085 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 8.247211e-01 | 0.084 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.247211e-01 | 0.084 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 8.247211e-01 | 0.084 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.247211e-01 | 0.084 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 8.247211e-01 | 0.084 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 8.247211e-01 | 0.084 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.247211e-01 | 0.084 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 8.247211e-01 | 0.084 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 8.247211e-01 | 0.084 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 8.247211e-01 | 0.084 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 8.247211e-01 | 0.084 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 8.248444e-01 | 0.084 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.265206e-01 | 0.083 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 8.280355e-01 | 0.082 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 8.280355e-01 | 0.082 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 8.280355e-01 | 0.082 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 8.280355e-01 | 0.082 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 8.280355e-01 | 0.082 | 0 | 0 |
| Defective CHSY1 causes TPBS | R-HSA-3595177 | 8.280355e-01 | 0.082 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis | R-HSA-9632974 | 8.280355e-01 | 0.082 | 0 | 0 |
| mRNA Editing: C to U Conversion | R-HSA-72200 | 8.280355e-01 | 0.082 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 8.280355e-01 | 0.082 | 0 | 0 |
| Cysteine formation from homocysteine | R-HSA-1614603 | 8.280355e-01 | 0.082 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 8.280355e-01 | 0.082 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 8.280355e-01 | 0.082 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 8.280355e-01 | 0.082 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 8.280355e-01 | 0.082 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 8.280355e-01 | 0.082 | 0 | 0 |
| Maturation of replicase proteins | R-HSA-9694301 | 8.280355e-01 | 0.082 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 8.309366e-01 | 0.080 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 8.309366e-01 | 0.080 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 8.310799e-01 | 0.080 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 8.310799e-01 | 0.080 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 8.310799e-01 | 0.080 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 8.310799e-01 | 0.080 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 8.349936e-01 | 0.078 | 1 | 1 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 8.349936e-01 | 0.078 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 8.349936e-01 | 0.078 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 8.353216e-01 | 0.078 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 8.357723e-01 | 0.078 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 8.357723e-01 | 0.078 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 8.388409e-01 | 0.076 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.393957e-01 | 0.076 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.446151e-01 | 0.073 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 8.461303e-01 | 0.073 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 8.461303e-01 | 0.073 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 8.461303e-01 | 0.073 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 8.461303e-01 | 0.073 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 8.461948e-01 | 0.073 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 8.468218e-01 | 0.072 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 8.468218e-01 | 0.072 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 8.468218e-01 | 0.072 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 8.468218e-01 | 0.072 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 8.468218e-01 | 0.072 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 8.468218e-01 | 0.072 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 8.476219e-01 | 0.072 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 8.476219e-01 | 0.072 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 8.476219e-01 | 0.072 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 8.518364e-01 | 0.070 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 8.518364e-01 | 0.070 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 8.530500e-01 | 0.069 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.530500e-01 | 0.069 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.547037e-01 | 0.068 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.557108e-01 | 0.068 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 8.558029e-01 | 0.068 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 8.558029e-01 | 0.068 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 8.558029e-01 | 0.068 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 8.558029e-01 | 0.068 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 8.558029e-01 | 0.068 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 8.558029e-01 | 0.068 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 8.558029e-01 | 0.068 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 8.558029e-01 | 0.068 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 8.558029e-01 | 0.068 | 0 | 0 |
| RSK activation | R-HSA-444257 | 8.558029e-01 | 0.068 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 8.558029e-01 | 0.068 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 8.581461e-01 | 0.066 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 8.598624e-01 | 0.066 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.598624e-01 | 0.066 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 8.598624e-01 | 0.066 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 8.601763e-01 | 0.065 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 8.609323e-01 | 0.065 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 8.611111e-01 | 0.065 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.622927e-01 | 0.064 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 8.627727e-01 | 0.064 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 8.628702e-01 | 0.064 | 1 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 8.645733e-01 | 0.063 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 8.653616e-01 | 0.063 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 8.663571e-01 | 0.062 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 8.663571e-01 | 0.062 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 8.663571e-01 | 0.062 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 8.663571e-01 | 0.062 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 8.663571e-01 | 0.062 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 8.693557e-01 | 0.061 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 8.693557e-01 | 0.061 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 8.722800e-01 | 0.059 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 8.731309e-01 | 0.059 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 8.731309e-01 | 0.059 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.754487e-01 | 0.058 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.766142e-01 | 0.057 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 8.776497e-01 | 0.057 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 8.790880e-01 | 0.056 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 8.790880e-01 | 0.056 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 8.790880e-01 | 0.056 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 8.790880e-01 | 0.056 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 8.790880e-01 | 0.056 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 8.790880e-01 | 0.056 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 8.790880e-01 | 0.056 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 8.790880e-01 | 0.056 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 8.790880e-01 | 0.056 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 8.790880e-01 | 0.056 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 8.801908e-01 | 0.055 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 8.835790e-01 | 0.054 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 8.835790e-01 | 0.054 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 8.835790e-01 | 0.054 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 8.835790e-01 | 0.054 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.835790e-01 | 0.054 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 8.835790e-01 | 0.054 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 8.835790e-01 | 0.054 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 8.835790e-01 | 0.054 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 8.835790e-01 | 0.054 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.835790e-01 | 0.054 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 8.840414e-01 | 0.054 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 8.850525e-01 | 0.053 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 8.850525e-01 | 0.053 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 8.857298e-01 | 0.053 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 8.892294e-01 | 0.051 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.892294e-01 | 0.051 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 8.926803e-01 | 0.049 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 8.935901e-01 | 0.049 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 8.960001e-01 | 0.048 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 8.972352e-01 | 0.047 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 8.972352e-01 | 0.047 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 8.972352e-01 | 0.047 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 8.972352e-01 | 0.047 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 8.986140e-01 | 0.046 | 0 | 0 |
| OADH complex synthesizes glutaryl-CoA from 2-OA | R-HSA-9858328 | 8.986140e-01 | 0.046 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 8.986140e-01 | 0.046 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 8.986140e-01 | 0.046 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 8.986140e-01 | 0.046 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 8.986140e-01 | 0.046 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 8.986140e-01 | 0.046 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 8.986140e-01 | 0.046 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 8.986140e-01 | 0.046 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 8.986140e-01 | 0.046 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 8.986140e-01 | 0.046 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 8.987251e-01 | 0.046 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 8.987251e-01 | 0.046 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.007008e-01 | 0.045 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.018042e-01 | 0.045 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 9.018042e-01 | 0.045 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 9.018042e-01 | 0.045 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 9.026328e-01 | 0.044 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 9.031756e-01 | 0.044 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.031756e-01 | 0.044 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.060329e-01 | 0.043 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 9.060329e-01 | 0.043 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.060329e-01 | 0.043 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.060329e-01 | 0.043 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.072264e-01 | 0.042 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.090613e-01 | 0.041 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 9.102586e-01 | 0.041 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 9.102586e-01 | 0.041 | 1 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.120078e-01 | 0.040 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 9.120167e-01 | 0.040 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 9.120167e-01 | 0.040 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 9.120167e-01 | 0.040 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.120167e-01 | 0.040 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 9.120167e-01 | 0.040 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 9.149878e-01 | 0.039 | 0 | 0 |
| FGFR2b ligand binding and activation | R-HSA-190377 | 9.149878e-01 | 0.039 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 9.149878e-01 | 0.039 | 0 | 0 |
| Conjugation of benzoate with glycine | R-HSA-177135 | 9.149878e-01 | 0.039 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 9.149878e-01 | 0.039 | 0 | 0 |
| Cholesterol biosynthesis via desmosterol | R-HSA-6807047 | 9.149878e-01 | 0.039 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 9.149878e-01 | 0.039 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 9.149878e-01 | 0.039 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 9.149878e-01 | 0.039 | 0 | 0 |
| LGI-ADAM interactions | R-HSA-5682910 | 9.149878e-01 | 0.039 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 9.152094e-01 | 0.038 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.152094e-01 | 0.038 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 9.152094e-01 | 0.038 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 9.152094e-01 | 0.038 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 9.152094e-01 | 0.038 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 9.152094e-01 | 0.038 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 9.152094e-01 | 0.038 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.152094e-01 | 0.038 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 9.167110e-01 | 0.038 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 9.168496e-01 | 0.038 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 9.169292e-01 | 0.038 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.185855e-01 | 0.037 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.185855e-01 | 0.037 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.185855e-01 | 0.037 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.196386e-01 | 0.036 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 9.201316e-01 | 0.036 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.205356e-01 | 0.036 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 9.205356e-01 | 0.036 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.209417e-01 | 0.036 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.235872e-01 | 0.035 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.235872e-01 | 0.035 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.235872e-01 | 0.035 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 9.236576e-01 | 0.034 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.236576e-01 | 0.034 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 9.236576e-01 | 0.034 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 9.236576e-01 | 0.034 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.236576e-01 | 0.034 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 9.236576e-01 | 0.034 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 9.239917e-01 | 0.034 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 9.287180e-01 | 0.032 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 9.287180e-01 | 0.032 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 9.287180e-01 | 0.032 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 9.287180e-01 | 0.032 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 9.287180e-01 | 0.032 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 9.287180e-01 | 0.032 | 0 | 0 |
| Scavenging by Class H Receptors | R-HSA-3000497 | 9.287180e-01 | 0.032 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 9.287180e-01 | 0.032 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 9.287180e-01 | 0.032 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 9.287180e-01 | 0.032 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 9.287180e-01 | 0.032 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 9.287180e-01 | 0.032 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 9.287180e-01 | 0.032 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.290546e-01 | 0.032 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.290546e-01 | 0.032 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.290799e-01 | 0.032 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.290799e-01 | 0.032 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 9.304416e-01 | 0.031 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 9.312220e-01 | 0.031 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 9.312220e-01 | 0.031 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 9.312220e-01 | 0.031 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.312220e-01 | 0.031 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 9.319656e-01 | 0.031 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.324388e-01 | 0.030 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.338342e-01 | 0.030 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 9.338342e-01 | 0.030 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.338342e-01 | 0.030 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.367397e-01 | 0.028 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.367397e-01 | 0.028 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 9.374910e-01 | 0.028 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 9.374910e-01 | 0.028 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.374910e-01 | 0.028 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.374910e-01 | 0.028 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 9.374910e-01 | 0.028 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.380999e-01 | 0.028 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.381680e-01 | 0.028 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 9.402313e-01 | 0.027 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 9.402313e-01 | 0.027 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 9.402313e-01 | 0.027 | 0 | 0 |
| Conjugation of salicylate with glycine | R-HSA-177128 | 9.402313e-01 | 0.027 | 0 | 0 |
| Proline catabolism | R-HSA-70688 | 9.402313e-01 | 0.027 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 9.402313e-01 | 0.027 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 9.402313e-01 | 0.027 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 9.402313e-01 | 0.027 | 0 | 0 |
| Estrogen biosynthesis | R-HSA-193144 | 9.402313e-01 | 0.027 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.407639e-01 | 0.027 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 9.427158e-01 | 0.026 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 9.427158e-01 | 0.026 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.427158e-01 | 0.026 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 9.427158e-01 | 0.026 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.427158e-01 | 0.026 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.436606e-01 | 0.025 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 9.437403e-01 | 0.025 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 9.444768e-01 | 0.025 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.444768e-01 | 0.025 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.446106e-01 | 0.025 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 9.446106e-01 | 0.025 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.449709e-01 | 0.025 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.464096e-01 | 0.024 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.464096e-01 | 0.024 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.482436e-01 | 0.023 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 9.482436e-01 | 0.023 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.486869e-01 | 0.023 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.489193e-01 | 0.023 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 9.498855e-01 | 0.022 | 0 | 0 |
| OGDH complex synthesizes succinyl-CoA from 2-OG | R-HSA-9853506 | 9.498855e-01 | 0.022 | 0 | 0 |
| FGFR2c ligand binding and activation | R-HSA-190375 | 9.498855e-01 | 0.022 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 9.498855e-01 | 0.022 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 9.498855e-01 | 0.022 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 9.498855e-01 | 0.022 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 9.498855e-01 | 0.022 | 0 | 0 |
| Mtb iron assimilation by chelation | R-HSA-1222449 | 9.498855e-01 | 0.022 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 9.498855e-01 | 0.022 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 9.498855e-01 | 0.022 | 0 | 0 |
| Eicosanoids | R-HSA-211979 | 9.504551e-01 | 0.022 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.504551e-01 | 0.022 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 9.516116e-01 | 0.022 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 9.516116e-01 | 0.022 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.516116e-01 | 0.022 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.516116e-01 | 0.022 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.516298e-01 | 0.022 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.517015e-01 | 0.021 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.525427e-01 | 0.021 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.553781e-01 | 0.020 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.553781e-01 | 0.020 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 9.553781e-01 | 0.020 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.562929e-01 | 0.019 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 9.564642e-01 | 0.019 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.567375e-01 | 0.019 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 9.571894e-01 | 0.019 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.571894e-01 | 0.019 | 0 | 0 |
| Free fatty acid receptors | R-HSA-444209 | 9.571894e-01 | 0.019 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 9.571894e-01 | 0.019 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.571894e-01 | 0.019 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 9.571894e-01 | 0.019 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.574456e-01 | 0.019 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.574456e-01 | 0.019 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 9.579808e-01 | 0.019 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 9.579808e-01 | 0.019 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 9.579808e-01 | 0.019 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 9.579808e-01 | 0.019 | 0 | 0 |
| The activation of arylsulfatases | R-HSA-1663150 | 9.579808e-01 | 0.019 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 9.579808e-01 | 0.019 | 0 | 0 |
| Vitamin B2 (riboflavin) metabolism | R-HSA-196843 | 9.579808e-01 | 0.019 | 0 | 0 |
| N-glycan trimming and elongation in the cis-Golgi | R-HSA-964739 | 9.579808e-01 | 0.019 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 9.579808e-01 | 0.019 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 9.579808e-01 | 0.019 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 9.579808e-01 | 0.019 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 9.579808e-01 | 0.019 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 9.579808e-01 | 0.019 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 9.579808e-01 | 0.019 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 9.579815e-01 | 0.019 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 9.600618e-01 | 0.018 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.600618e-01 | 0.018 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.602391e-01 | 0.018 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.604733e-01 | 0.018 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.606442e-01 | 0.017 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 9.627069e-01 | 0.017 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 9.627069e-01 | 0.017 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 9.630414e-01 | 0.016 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 9.630414e-01 | 0.016 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 9.630414e-01 | 0.016 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.630414e-01 | 0.016 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 9.630414e-01 | 0.016 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.630414e-01 | 0.016 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.636271e-01 | 0.016 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 9.647688e-01 | 0.016 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 9.647688e-01 | 0.016 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 9.647688e-01 | 0.016 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 9.647688e-01 | 0.016 | 0 | 0 |
| Synthesis of 12-eicosatetraenoic acid derivatives | R-HSA-2142712 | 9.647688e-01 | 0.016 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 9.647688e-01 | 0.016 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 9.647688e-01 | 0.016 | 0 | 0 |
| Protein repair | R-HSA-5676934 | 9.647688e-01 | 0.016 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 9.647688e-01 | 0.016 | 0 | 0 |
| Transport and metabolism of PAPS | R-HSA-174362 | 9.647688e-01 | 0.016 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.649529e-01 | 0.015 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.673107e-01 | 0.014 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.681203e-01 | 0.014 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 9.681203e-01 | 0.014 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.681203e-01 | 0.014 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.685157e-01 | 0.014 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.685446e-01 | 0.014 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 9.704606e-01 | 0.013 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 9.704606e-01 | 0.013 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 9.704606e-01 | 0.013 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 9.704606e-01 | 0.013 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 9.704606e-01 | 0.013 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.713738e-01 | 0.013 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.713738e-01 | 0.013 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.713738e-01 | 0.013 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 9.719587e-01 | 0.012 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.725231e-01 | 0.012 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.725231e-01 | 0.012 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.725290e-01 | 0.012 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.738345e-01 | 0.012 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.739190e-01 | 0.011 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.743874e-01 | 0.011 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.752330e-01 | 0.011 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.752330e-01 | 0.011 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 9.752330e-01 | 0.011 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 9.752330e-01 | 0.011 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 9.752330e-01 | 0.011 | 0 | 0 |
| Vitamin B6 activation to pyridoxal phosphate | R-HSA-964975 | 9.752330e-01 | 0.011 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 9.752330e-01 | 0.011 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 9.752330e-01 | 0.011 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 9.752330e-01 | 0.011 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 9.752330e-01 | 0.011 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.757136e-01 | 0.011 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.767582e-01 | 0.010 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.777216e-01 | 0.010 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.781078e-01 | 0.010 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 9.785487e-01 | 0.009 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 9.792347e-01 | 0.009 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.792347e-01 | 0.009 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.792347e-01 | 0.009 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 9.792347e-01 | 0.009 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 9.792347e-01 | 0.009 | 0 | 0 |
| Synthesis of 15-eicosatetraenoic acid derivatives | R-HSA-2142770 | 9.792347e-01 | 0.009 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 9.792347e-01 | 0.009 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 9.792347e-01 | 0.009 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 9.792347e-01 | 0.009 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.796340e-01 | 0.009 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.796340e-01 | 0.009 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.796340e-01 | 0.009 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 9.798855e-01 | 0.009 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.808800e-01 | 0.008 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.808800e-01 | 0.008 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.810695e-01 | 0.008 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.810695e-01 | 0.008 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.821152e-01 | 0.008 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 9.824844e-01 | 0.008 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 9.825900e-01 | 0.008 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.825900e-01 | 0.008 | 0 | 0 |
| Activated point mutants of FGFR2 | R-HSA-2033519 | 9.825900e-01 | 0.008 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 9.825900e-01 | 0.008 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 9.825900e-01 | 0.008 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.833148e-01 | 0.007 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.833148e-01 | 0.007 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.835606e-01 | 0.007 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 9.849456e-01 | 0.007 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.849456e-01 | 0.007 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.850860e-01 | 0.007 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 9.852947e-01 | 0.006 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.852947e-01 | 0.006 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 9.854033e-01 | 0.006 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 9.854033e-01 | 0.006 | 0 | 0 |
| Amino Acid conjugation | R-HSA-156587 | 9.854033e-01 | 0.006 | 0 | 0 |
| Conjugation of carboxylic acids | R-HSA-159424 | 9.854033e-01 | 0.006 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 9.854033e-01 | 0.006 | 0 | 0 |
| Transport of nucleotide sugars | R-HSA-727802 | 9.854033e-01 | 0.006 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 9.854033e-01 | 0.006 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.854033e-01 | 0.006 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.854511e-01 | 0.006 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.858959e-01 | 0.006 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.870689e-01 | 0.006 | 0 | 0 |
| Mucopolysaccharidoses | R-HSA-2206281 | 9.870689e-01 | 0.006 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.873235e-01 | 0.006 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.877621e-01 | 0.005 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.877621e-01 | 0.005 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.877621e-01 | 0.005 | 0 | 0 |
| Keratan sulfate degradation | R-HSA-2022857 | 9.877621e-01 | 0.005 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.877621e-01 | 0.005 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.877642e-01 | 0.005 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 9.879930e-01 | 0.005 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.888992e-01 | 0.005 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.888992e-01 | 0.005 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.895554e-01 | 0.005 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.897399e-01 | 0.004 | 0 | 0 |
| FGFR2 ligand binding and activation | R-HSA-190241 | 9.897399e-01 | 0.004 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 9.897399e-01 | 0.004 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.909789e-01 | 0.004 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 9.913108e-01 | 0.004 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.913108e-01 | 0.004 | 0 | 0 |
| CS-GAG biosynthesis | R-HSA-2022870 | 9.913981e-01 | 0.004 | 0 | 0 |
| Miscellaneous substrates | R-HSA-211958 | 9.913981e-01 | 0.004 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.913981e-01 | 0.004 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.913981e-01 | 0.004 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 9.913981e-01 | 0.004 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.913981e-01 | 0.004 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.913981e-01 | 0.004 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.915431e-01 | 0.004 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.922853e-01 | 0.003 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.923160e-01 | 0.003 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 9.927884e-01 | 0.003 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.927884e-01 | 0.003 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 9.927884e-01 | 0.003 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 9.930002e-01 | 0.003 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.931055e-01 | 0.003 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.931055e-01 | 0.003 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 9.936920e-01 | 0.003 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.939541e-01 | 0.003 | 0 | 0 |
| Fatty acids | R-HSA-211935 | 9.939541e-01 | 0.003 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.939541e-01 | 0.003 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.939541e-01 | 0.003 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.939541e-01 | 0.003 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.940036e-01 | 0.003 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.940036e-01 | 0.003 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.940036e-01 | 0.003 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.943080e-01 | 0.002 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.946714e-01 | 0.002 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.948055e-01 | 0.002 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.948055e-01 | 0.002 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.949314e-01 | 0.002 | 0 | 0 |
| Synthesis of dolichyl-phosphate | R-HSA-446199 | 9.949314e-01 | 0.002 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.954186e-01 | 0.002 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 9.957507e-01 | 0.002 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.957507e-01 | 0.002 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 9.957507e-01 | 0.002 | 0 | 0 |
| Retinoid cycle disease events | R-HSA-2453864 | 9.957507e-01 | 0.002 | 0 | 0 |
| Diseases associated with visual transduction | R-HSA-2474795 | 9.957507e-01 | 0.002 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.957507e-01 | 0.002 | 0 | 0 |
| Diseases of the neuronal system | R-HSA-9675143 | 9.957507e-01 | 0.002 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.957507e-01 | 0.002 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.957507e-01 | 0.002 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.959382e-01 | 0.002 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.961757e-01 | 0.002 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.962406e-01 | 0.002 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.962406e-01 | 0.002 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.964377e-01 | 0.002 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.964377e-01 | 0.002 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.964377e-01 | 0.002 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.965224e-01 | 0.002 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.967852e-01 | 0.001 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.967852e-01 | 0.001 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.967852e-01 | 0.001 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.968107e-01 | 0.001 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.969177e-01 | 0.001 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.970136e-01 | 0.001 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.970136e-01 | 0.001 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.970136e-01 | 0.001 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.973327e-01 | 0.001 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.973465e-01 | 0.001 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.974283e-01 | 0.001 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.974965e-01 | 0.001 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 9.975627e-01 | 0.001 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.976740e-01 | 0.001 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.976841e-01 | 0.001 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.976841e-01 | 0.001 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.976841e-01 | 0.001 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.976929e-01 | 0.001 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.976929e-01 | 0.001 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.979008e-01 | 0.001 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.979008e-01 | 0.001 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.979013e-01 | 0.001 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.979013e-01 | 0.001 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.979013e-01 | 0.001 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.979798e-01 | 0.001 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.979944e-01 | 0.001 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.979944e-01 | 0.001 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.980961e-01 | 0.001 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.981747e-01 | 0.001 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.982875e-01 | 0.001 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.984773e-01 | 0.001 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.987637e-01 | 0.001 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.987651e-01 | 0.001 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.987957e-01 | 0.001 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.989361e-01 | 0.000 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.989636e-01 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.990516e-01 | 0.000 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.990928e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.991194e-01 | 0.000 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.991771e-01 | 0.000 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.992345e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.992718e-01 | 0.000 | 0 | 0 |
| Phosphate bond hydrolysis by NUDT proteins | R-HSA-2393930 | 9.992718e-01 | 0.000 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.993409e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.993512e-01 | 0.000 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.993877e-01 | 0.000 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.993896e-01 | 0.000 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.993896e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 9.993896e-01 | 0.000 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.993896e-01 | 0.000 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.994727e-01 | 0.000 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.994883e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.994883e-01 | 0.000 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.995217e-01 | 0.000 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.995460e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.995620e-01 | 0.000 | 0 | 0 |
| Ubiquinol biosynthesis | R-HSA-2142789 | 9.995711e-01 | 0.000 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.995711e-01 | 0.000 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.995711e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.996521e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.996986e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.997110e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.997110e-01 | 0.000 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.997474e-01 | 0.000 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.997474e-01 | 0.000 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.997489e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.997492e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.997768e-01 | 0.000 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.998062e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.998063e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.998156e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.998160e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.998166e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.998184e-01 | 0.000 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.998225e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.998304e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.998316e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.998430e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.998638e-01 | 0.000 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.998673e-01 | 0.000 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.998753e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.998839e-01 | 0.000 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.998871e-01 | 0.000 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.998955e-01 | 0.000 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.998955e-01 | 0.000 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.999004e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999096e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.999107e-01 | 0.000 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.999124e-01 | 0.000 | 0 | 0 |
| The canonical retinoid cycle in rods (twilight vision) | R-HSA-2453902 | 9.999124e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.999146e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.999155e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.999267e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.999316e-01 | 0.000 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.999385e-01 | 0.000 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.999462e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.999484e-01 | 0.000 | 0 | 0 |
| Keratan sulfate/keratin metabolism | R-HSA-1638074 | 9.999568e-01 | 0.000 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.999638e-01 | 0.000 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.999659e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999661e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999667e-01 | 0.000 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.999696e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999725e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999849e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999867e-01 | 0.000 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.999875e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999917e-01 | 0.000 | 0 | 0 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 9.999919e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999925e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.999926e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999932e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.999947e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999947e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999958e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.999964e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.999965e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999971e-01 | 0.000 | 0 | 0 |
| Latent infection - Other responses of Mtb to phagocytosis | R-HSA-1222499 | 9.999974e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.999975e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999975e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999981e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.999982e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.999985e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999989e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999989e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.999991e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.999991e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.999991e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999992e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999993e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999995e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999998e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999998e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999999e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999999e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 1.000000e+00 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | -0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | -0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 1 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.110223e-16 | 15.955 | 1 | 0 |
| M Phase | R-HSA-68886 | 1.110223e-16 | 15.955 | 1 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.110223e-16 | 15.955 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.110223e-16 | 15.955 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 2.220446e-16 | 15.654 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.330669e-16 | 15.477 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.440892e-16 | 15.353 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 4.218847e-15 | 14.375 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 6.661338e-15 | 14.176 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.643130e-14 | 13.784 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 6.183942e-14 | 13.209 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 8.459899e-14 | 13.073 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.303402e-13 | 12.885 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.303402e-13 | 12.885 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.544631e-13 | 12.594 | 1 | 0 |
| Cellular Senescence | R-HSA-2559583 | 5.552225e-13 | 12.256 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.285971e-12 | 11.891 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.294742e-12 | 11.888 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 3.360756e-12 | 11.474 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 4.033995e-12 | 11.394 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 6.514234e-12 | 11.186 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 6.514234e-12 | 11.186 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 7.674750e-12 | 11.115 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.046530e-11 | 10.980 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.420530e-11 | 10.848 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 2.387612e-11 | 10.622 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.432266e-11 | 10.614 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 2.821143e-11 | 10.550 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 3.250922e-11 | 10.488 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 4.041745e-11 | 10.393 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 3.966316e-11 | 10.402 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 3.966316e-11 | 10.402 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 4.578038e-11 | 10.339 | 1 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 6.523437e-11 | 10.186 | 1 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 7.197298e-11 | 10.143 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 7.100087e-11 | 10.149 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 7.752721e-11 | 10.111 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 8.190570e-11 | 10.087 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 9.617707e-11 | 10.017 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 9.617707e-11 | 10.017 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.581597e-10 | 9.801 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.884112e-10 | 9.725 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.980854e-10 | 9.703 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 2.060661e-10 | 9.686 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 2.488041e-10 | 9.604 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 3.207227e-10 | 9.494 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 3.385601e-10 | 9.470 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 3.641298e-10 | 9.439 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 3.760023e-10 | 9.425 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 4.860535e-10 | 9.313 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 6.202276e-10 | 9.207 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 7.686279e-10 | 9.114 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 8.039339e-10 | 9.095 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 8.626594e-10 | 9.064 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.389281e-10 | 9.076 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.260487e-09 | 8.899 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.263214e-09 | 8.899 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.453696e-09 | 8.838 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.638031e-09 | 8.786 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 2.052642e-09 | 8.688 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 2.052642e-09 | 8.688 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 2.108693e-09 | 8.676 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 2.166009e-09 | 8.664 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 2.464692e-09 | 8.608 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 2.774915e-09 | 8.557 | 1 | 1 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 2.863189e-09 | 8.543 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 3.042070e-09 | 8.517 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 4.757772e-09 | 8.323 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 5.513946e-09 | 8.259 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.262727e-09 | 8.203 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 6.719553e-09 | 8.173 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 6.735810e-09 | 8.172 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 8.094568e-09 | 8.092 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 8.942464e-09 | 8.049 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.027139e-09 | 8.044 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 9.724605e-09 | 8.012 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.388225e-09 | 8.027 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.023976e-08 | 7.990 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.064802e-08 | 7.973 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.086788e-08 | 7.964 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 1.190970e-08 | 7.924 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 1.366020e-08 | 7.865 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 1.460825e-08 | 7.835 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.841472e-08 | 7.735 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 2.064183e-08 | 7.685 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 2.068400e-08 | 7.684 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.431991e-08 | 7.614 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 2.539602e-08 | 7.595 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.923977e-08 | 7.534 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.923977e-08 | 7.534 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 3.067940e-08 | 7.513 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 3.323216e-08 | 7.478 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 3.653108e-08 | 7.437 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 3.980050e-08 | 7.400 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 5.243635e-08 | 7.280 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 5.176364e-08 | 7.286 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 5.721674e-08 | 7.242 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 5.785013e-08 | 7.238 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 6.285848e-08 | 7.202 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 6.621929e-08 | 7.179 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 6.734680e-08 | 7.172 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 6.762532e-08 | 7.170 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 7.207160e-08 | 7.142 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 7.405593e-08 | 7.130 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 7.405593e-08 | 7.130 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 7.626993e-08 | 7.118 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 8.035527e-08 | 7.095 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 7.671593e-08 | 7.115 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 1.088706e-07 | 6.963 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.220588e-07 | 6.913 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.398390e-07 | 6.854 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.539066e-07 | 6.813 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 1.539560e-07 | 6.813 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 1.674574e-07 | 6.776 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.999054e-07 | 6.699 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.887123e-07 | 6.724 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 2.000526e-07 | 6.699 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 2.006248e-07 | 6.698 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.048533e-07 | 6.689 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.226196e-07 | 6.652 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 2.370048e-07 | 6.625 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 2.445215e-07 | 6.612 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 2.853534e-07 | 6.545 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 3.148608e-07 | 6.502 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 3.184978e-07 | 6.497 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 3.282639e-07 | 6.484 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 3.765706e-07 | 6.424 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 4.358370e-07 | 6.361 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 4.406726e-07 | 6.356 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 4.152533e-07 | 6.382 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 4.788854e-07 | 6.320 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 5.141150e-07 | 6.289 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 5.339098e-07 | 6.273 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 5.795566e-07 | 6.237 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 6.169762e-07 | 6.210 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 6.700895e-07 | 6.174 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 6.700895e-07 | 6.174 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 6.922802e-07 | 6.160 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 7.268255e-07 | 6.139 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 7.062323e-07 | 6.151 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 7.509708e-07 | 6.124 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 7.857275e-07 | 6.105 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.036475e-07 | 6.095 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 8.140492e-07 | 6.089 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 8.509767e-07 | 6.070 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.870428e-07 | 6.006 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 1.002561e-06 | 5.999 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.040241e-06 | 5.983 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.219650e-06 | 5.914 | 1 | 1 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 1.280355e-06 | 5.893 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.301012e-06 | 5.886 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.369288e-06 | 5.864 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.503283e-06 | 5.823 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.581354e-06 | 5.801 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 1.632446e-06 | 5.787 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.671333e-06 | 5.777 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.689484e-06 | 5.772 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 1.714639e-06 | 5.766 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.950100e-06 | 5.710 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.978346e-06 | 5.704 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 1.991661e-06 | 5.701 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.064424e-06 | 5.685 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 2.115494e-06 | 5.675 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 2.117544e-06 | 5.674 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 2.311555e-06 | 5.636 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.443224e-06 | 5.612 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 2.808280e-06 | 5.552 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 2.818255e-06 | 5.550 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 3.021344e-06 | 5.520 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 3.046652e-06 | 5.516 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 3.142431e-06 | 5.503 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 3.265877e-06 | 5.486 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 3.426754e-06 | 5.465 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 3.566691e-06 | 5.448 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 3.579401e-06 | 5.446 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 3.916861e-06 | 5.407 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 3.980479e-06 | 5.400 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 4.468389e-06 | 5.350 | 0 | 0 |
| Depurination | R-HSA-73927 | 4.784572e-06 | 5.320 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 5.201483e-06 | 5.284 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 5.362541e-06 | 5.271 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 5.362541e-06 | 5.271 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 4.887827e-06 | 5.311 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 4.887827e-06 | 5.311 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 5.493152e-06 | 5.260 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 5.555122e-06 | 5.255 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 6.053057e-06 | 5.218 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 6.367210e-06 | 5.196 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 6.466771e-06 | 5.189 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 7.896154e-06 | 5.103 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 8.310920e-06 | 5.080 | 0 | 0 |
| Kinesins | R-HSA-983189 | 8.451204e-06 | 5.073 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 1.075611e-05 | 4.968 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.131087e-05 | 4.947 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 1.135915e-05 | 4.945 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.378660e-05 | 4.861 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 1.423598e-05 | 4.847 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.441842e-05 | 4.841 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.587097e-05 | 4.799 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.505919e-05 | 4.822 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 1.640781e-05 | 4.785 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.742021e-05 | 4.759 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.766531e-05 | 4.753 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 1.807557e-05 | 4.743 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 2.078240e-05 | 4.682 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 2.120651e-05 | 4.674 | 0 | 0 |
| Protein folding | R-HSA-391251 | 2.127647e-05 | 4.672 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 2.154510e-05 | 4.667 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 2.361484e-05 | 4.627 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.433031e-05 | 4.614 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 2.528620e-05 | 4.597 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 2.535991e-05 | 4.596 | 1 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 2.611086e-05 | 4.583 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 2.649733e-05 | 4.577 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.865116e-05 | 4.543 | 1 | 1 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.892928e-05 | 4.539 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 2.892928e-05 | 4.539 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 2.941328e-05 | 4.531 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 2.973697e-05 | 4.527 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 3.026798e-05 | 4.519 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 3.188673e-05 | 4.496 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 3.292830e-05 | 4.482 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 4.636757e-05 | 4.334 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 4.636757e-05 | 4.334 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 4.537412e-05 | 4.343 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 4.652528e-05 | 4.332 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 4.652528e-05 | 4.332 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 4.652528e-05 | 4.332 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 4.652528e-05 | 4.332 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 4.652528e-05 | 4.332 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 4.847496e-05 | 4.314 | 1 | 1 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 4.847496e-05 | 4.314 | 1 | 1 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 5.048285e-05 | 4.297 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 5.108776e-05 | 4.292 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 6.008923e-05 | 4.221 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 6.230132e-05 | 4.206 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 6.378996e-05 | 4.195 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 7.389167e-05 | 4.131 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 7.799472e-05 | 4.108 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 8.108775e-05 | 4.091 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 8.676942e-05 | 4.062 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 8.676942e-05 | 4.062 | 0 | 0 |
| Translation | R-HSA-72766 | 8.925371e-05 | 4.049 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 9.303153e-05 | 4.031 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.025290e-04 | 3.989 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.094087e-04 | 3.961 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.002113e-04 | 3.999 | 1 | 1 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 1.096768e-04 | 3.960 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 1.002113e-04 | 3.999 | 0 | 0 |
| S Phase | R-HSA-69242 | 1.005621e-04 | 3.998 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 1.094087e-04 | 3.961 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.023894e-04 | 3.990 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.023894e-04 | 3.990 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 9.872892e-05 | 4.006 | 0 | 0 |
| Immune System | R-HSA-168256 | 1.115620e-04 | 3.952 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 1.169504e-04 | 3.932 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.180125e-04 | 3.928 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.213909e-04 | 3.916 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.391025e-04 | 3.857 | 1 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.414216e-04 | 3.849 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.414216e-04 | 3.849 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.414216e-04 | 3.849 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.427516e-04 | 3.845 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.439955e-04 | 3.842 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.439955e-04 | 3.842 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 1.515390e-04 | 3.819 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 1.566117e-04 | 3.805 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 1.612556e-04 | 3.792 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.621163e-04 | 3.790 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 1.705139e-04 | 3.768 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 1.705139e-04 | 3.768 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.843879e-04 | 3.734 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.857764e-04 | 3.731 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.883132e-04 | 3.725 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.949573e-04 | 3.710 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 1.964589e-04 | 3.707 | 1 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 1.964589e-04 | 3.707 | 1 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 2.006623e-04 | 3.698 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 2.028436e-04 | 3.693 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 2.108720e-04 | 3.676 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 2.251441e-04 | 3.648 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 2.346381e-04 | 3.630 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 2.356854e-04 | 3.628 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 2.363421e-04 | 3.626 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 2.365224e-04 | 3.626 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 2.431143e-04 | 3.614 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 2.457587e-04 | 3.609 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.457587e-04 | 3.609 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 2.461021e-04 | 3.609 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 2.572567e-04 | 3.590 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 2.576910e-04 | 3.589 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.661419e-04 | 3.575 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.735363e-04 | 3.563 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 2.884785e-04 | 3.540 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 3.247394e-04 | 3.488 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 3.334154e-04 | 3.477 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 3.215165e-04 | 3.493 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 3.504805e-04 | 3.455 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 3.506075e-04 | 3.455 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 3.589067e-04 | 3.445 | 1 | 1 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 3.617685e-04 | 3.442 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 3.654594e-04 | 3.437 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 3.909732e-04 | 3.408 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 3.909732e-04 | 3.408 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 3.928495e-04 | 3.406 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 4.002589e-04 | 3.398 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 4.496893e-04 | 3.347 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.742128e-04 | 3.324 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 4.790313e-04 | 3.320 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 4.793720e-04 | 3.319 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 5.041607e-04 | 3.297 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 5.277570e-04 | 3.278 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 5.300393e-04 | 3.276 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 5.415148e-04 | 3.266 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 5.415148e-04 | 3.266 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 5.596884e-04 | 3.252 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 5.604057e-04 | 3.251 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 5.604057e-04 | 3.251 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 5.612526e-04 | 3.251 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 5.642347e-04 | 3.249 | 1 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 5.785389e-04 | 3.238 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 6.076304e-04 | 3.216 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 6.534996e-04 | 3.185 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 7.552287e-04 | 3.122 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 7.661221e-04 | 3.116 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 7.685012e-04 | 3.114 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 7.836452e-04 | 3.106 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 7.887203e-04 | 3.103 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 7.887795e-04 | 3.103 | 1 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 7.994423e-04 | 3.097 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 7.994423e-04 | 3.097 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 8.288833e-04 | 3.082 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.981946e-04 | 3.047 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 8.981946e-04 | 3.047 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 9.167477e-04 | 3.038 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 9.262891e-04 | 3.033 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 9.270053e-04 | 3.033 | 1 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 9.378750e-04 | 3.028 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 9.429207e-04 | 3.026 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 9.429207e-04 | 3.026 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 1.049896e-03 | 2.979 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.056447e-03 | 2.976 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.056447e-03 | 2.976 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 1.097233e-03 | 2.960 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.127948e-03 | 2.948 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.127948e-03 | 2.948 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 1.134098e-03 | 2.945 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 1.134098e-03 | 2.945 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 1.201215e-03 | 2.920 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 1.296462e-03 | 2.887 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.213837e-03 | 2.916 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.502244e-03 | 2.823 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.502244e-03 | 2.823 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 1.502244e-03 | 2.823 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 1.316801e-03 | 2.880 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.296695e-03 | 2.887 | 1 | 1 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 1.347271e-03 | 2.871 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 1.296462e-03 | 2.887 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 1.347271e-03 | 2.871 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 1.478932e-03 | 2.830 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.455093e-03 | 2.837 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.369061e-03 | 2.864 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 1.542097e-03 | 2.812 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.586166e-03 | 2.800 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 1.587077e-03 | 2.799 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 1.912729e-03 | 2.718 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.913165e-03 | 2.718 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.916350e-03 | 2.718 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 1.981452e-03 | 2.703 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 2.036116e-03 | 2.691 | 1 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 2.107396e-03 | 2.676 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 2.175612e-03 | 2.662 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 2.247621e-03 | 2.648 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 2.247621e-03 | 2.648 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 2.252440e-03 | 2.647 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.345769e-03 | 2.630 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 2.350213e-03 | 2.629 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.368553e-03 | 2.626 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 2.496878e-03 | 2.603 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.496878e-03 | 2.603 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 2.496878e-03 | 2.603 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.670413e-03 | 2.573 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.719415e-03 | 2.566 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 2.731539e-03 | 2.564 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.731539e-03 | 2.564 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.752398e-03 | 2.560 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 2.950419e-03 | 2.530 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 3.076146e-03 | 2.512 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 3.086337e-03 | 2.511 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 3.123978e-03 | 2.505 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 3.129711e-03 | 2.504 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 3.163716e-03 | 2.500 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 3.187738e-03 | 2.497 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 3.236579e-03 | 2.490 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 3.236579e-03 | 2.490 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 3.267985e-03 | 2.486 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 3.350801e-03 | 2.475 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 3.350801e-03 | 2.475 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.350801e-03 | 2.475 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 3.350801e-03 | 2.475 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 3.350801e-03 | 2.475 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 3.410548e-03 | 2.467 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 3.442216e-03 | 2.463 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.492215e-03 | 2.457 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.541800e-03 | 2.451 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 3.651338e-03 | 2.438 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 3.675469e-03 | 2.435 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 3.675469e-03 | 2.435 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 3.724977e-03 | 2.429 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.814531e-03 | 2.419 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 3.847990e-03 | 2.415 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 3.847990e-03 | 2.415 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 3.872496e-03 | 2.412 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 3.872496e-03 | 2.412 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 3.901950e-03 | 2.409 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 3.901950e-03 | 2.409 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 3.901950e-03 | 2.409 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 3.901950e-03 | 2.409 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 4.002233e-03 | 2.398 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 4.116186e-03 | 2.386 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 4.241273e-03 | 2.373 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 5.661985e-03 | 2.247 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 5.328493e-03 | 2.273 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 4.350963e-03 | 2.361 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 4.410972e-03 | 2.355 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 5.173034e-03 | 2.286 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 5.173034e-03 | 2.286 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 4.630357e-03 | 2.334 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 5.143473e-03 | 2.289 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 4.524648e-03 | 2.344 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 5.462654e-03 | 2.263 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 4.668656e-03 | 2.331 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 5.218723e-03 | 2.282 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 4.630357e-03 | 2.334 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 4.630357e-03 | 2.334 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 5.462654e-03 | 2.263 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 5.279906e-03 | 2.277 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 4.635717e-03 | 2.334 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 4.350963e-03 | 2.361 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 5.173034e-03 | 2.286 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 4.349116e-03 | 2.362 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 5.328493e-03 | 2.273 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 5.469414e-03 | 2.262 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 4.905768e-03 | 2.309 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 4.278471e-03 | 2.369 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 5.684636e-03 | 2.245 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.410972e-03 | 2.355 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 4.557577e-03 | 2.341 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 5.706615e-03 | 2.244 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 5.706615e-03 | 2.244 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 5.901153e-03 | 2.229 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 5.901153e-03 | 2.229 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 6.222684e-03 | 2.206 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 6.643171e-03 | 2.178 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 6.686334e-03 | 2.175 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 6.742682e-03 | 2.171 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 6.988212e-03 | 2.156 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 7.006337e-03 | 2.155 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 7.384464e-03 | 2.132 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 7.597395e-03 | 2.119 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 7.819376e-03 | 2.107 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 7.832074e-03 | 2.106 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 7.832074e-03 | 2.106 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 7.832074e-03 | 2.106 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 7.832074e-03 | 2.106 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 7.832074e-03 | 2.106 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 7.846511e-03 | 2.105 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 7.895301e-03 | 2.103 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 8.064580e-03 | 2.093 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 8.939566e-03 | 2.049 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 8.939566e-03 | 2.049 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 8.939566e-03 | 2.049 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 9.076063e-03 | 2.042 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 9.124008e-03 | 2.040 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 9.124008e-03 | 2.040 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.211070e-03 | 2.036 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.243906e-03 | 2.034 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 9.243906e-03 | 2.034 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 9.538438e-03 | 2.021 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 9.681063e-03 | 2.014 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 1.003108e-02 | 1.999 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 1.003108e-02 | 1.999 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.003108e-02 | 1.999 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 1.003108e-02 | 1.999 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.046392e-02 | 1.980 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 1.046392e-02 | 1.980 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.046392e-02 | 1.980 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 1.046392e-02 | 1.980 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 1.046392e-02 | 1.980 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 1.074806e-02 | 1.969 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 1.074997e-02 | 1.969 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 1.130576e-02 | 1.947 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.157350e-02 | 1.937 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 1.157350e-02 | 1.937 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.157350e-02 | 1.937 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.191975e-02 | 1.924 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.207664e-02 | 1.918 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 1.215510e-02 | 1.915 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 1.224616e-02 | 1.912 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 1.247645e-02 | 1.904 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.293528e-02 | 1.888 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.293528e-02 | 1.888 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 1.293528e-02 | 1.888 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 1.293528e-02 | 1.888 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 1.293528e-02 | 1.888 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.348322e-02 | 1.870 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 1.373105e-02 | 1.862 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.382538e-02 | 1.859 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.382538e-02 | 1.859 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.382538e-02 | 1.859 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 1.384217e-02 | 1.859 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 1.384217e-02 | 1.859 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 1.399395e-02 | 1.854 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 1.399395e-02 | 1.854 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 1.408158e-02 | 1.851 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.413509e-02 | 1.850 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.440372e-02 | 1.842 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 1.440372e-02 | 1.842 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 1.440372e-02 | 1.842 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.505306e-02 | 1.822 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 1.505306e-02 | 1.822 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 1.534972e-02 | 1.814 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.538291e-02 | 1.813 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 1.539579e-02 | 1.813 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 1.589126e-02 | 1.799 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.638085e-02 | 1.786 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 1.708832e-02 | 1.767 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 1.708832e-02 | 1.767 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 1.718204e-02 | 1.765 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 1.726829e-02 | 1.763 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 1.726829e-02 | 1.763 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.738705e-02 | 1.760 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.738705e-02 | 1.760 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.738705e-02 | 1.760 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.738705e-02 | 1.760 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.738705e-02 | 1.760 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.738705e-02 | 1.760 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.817767e-02 | 1.740 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.824668e-02 | 1.739 | 0 | 0 |
| Disease | R-HSA-1643685 | 1.859450e-02 | 1.731 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.871136e-02 | 1.728 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 1.926042e-02 | 1.715 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 1.926042e-02 | 1.715 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 1.932204e-02 | 1.714 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 1.932204e-02 | 1.714 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 1.999843e-02 | 1.699 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 2.003047e-02 | 1.698 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 2.003047e-02 | 1.698 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 2.003047e-02 | 1.698 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.008800e-02 | 1.697 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 2.009086e-02 | 1.697 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.009086e-02 | 1.697 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 2.044326e-02 | 1.689 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 2.075506e-02 | 1.683 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 2.187475e-02 | 1.660 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 2.285836e-02 | 1.641 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 2.285836e-02 | 1.641 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 2.285836e-02 | 1.641 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.441210e-02 | 1.612 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 2.939140e-02 | 1.532 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.606947e-02 | 1.584 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 3.003487e-02 | 1.522 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 2.883149e-02 | 1.540 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 2.965709e-02 | 1.528 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 2.731724e-02 | 1.564 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 3.289974e-02 | 1.483 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 2.724565e-02 | 1.565 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 2.724565e-02 | 1.565 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 3.003487e-02 | 1.522 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 2.724565e-02 | 1.565 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.003487e-02 | 1.522 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 3.330522e-02 | 1.477 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 2.965709e-02 | 1.528 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 2.716826e-02 | 1.566 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 2.339169e-02 | 1.631 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 2.339169e-02 | 1.631 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 2.537753e-02 | 1.596 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 2.750327e-02 | 1.561 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 2.485384e-02 | 1.605 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 2.380818e-02 | 1.623 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 2.751078e-02 | 1.560 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 3.330522e-02 | 1.477 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 2.751078e-02 | 1.560 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.606947e-02 | 1.584 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 2.965709e-02 | 1.528 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 2.327349e-02 | 1.633 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 2.327349e-02 | 1.633 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.353913e-02 | 1.628 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 2.865113e-02 | 1.543 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 2.385536e-02 | 1.622 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 2.230944e-02 | 1.652 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 2.537753e-02 | 1.596 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 2.807827e-02 | 1.552 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 3.011729e-02 | 1.521 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 2.731724e-02 | 1.564 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.939140e-02 | 1.532 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 2.965709e-02 | 1.528 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 2.537753e-02 | 1.596 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 3.377496e-02 | 1.471 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 3.377496e-02 | 1.471 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.395431e-02 | 1.469 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 3.439586e-02 | 1.463 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 3.439586e-02 | 1.463 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 3.458499e-02 | 1.461 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 3.499426e-02 | 1.456 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 3.499426e-02 | 1.456 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.499426e-02 | 1.456 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 3.499426e-02 | 1.456 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 3.566850e-02 | 1.448 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 3.581124e-02 | 1.446 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 3.581124e-02 | 1.446 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 3.581124e-02 | 1.446 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.666134e-02 | 1.436 | 0 | 0 |
| Inhibition of Host mRNA Processing and RNA Silencing | R-HSA-168315 | 3.666134e-02 | 1.436 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.666134e-02 | 1.436 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 3.745665e-02 | 1.426 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 3.833789e-02 | 1.416 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 3.856410e-02 | 1.414 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 4.124193e-02 | 1.385 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 4.124193e-02 | 1.385 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 4.135396e-02 | 1.383 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 4.252134e-02 | 1.371 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 4.252134e-02 | 1.371 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 4.284780e-02 | 1.368 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 4.307431e-02 | 1.366 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 4.327035e-02 | 1.364 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.337997e-02 | 1.363 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 4.337997e-02 | 1.363 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 4.337997e-02 | 1.363 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.337997e-02 | 1.363 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 4.369410e-02 | 1.360 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 4.369410e-02 | 1.360 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 4.393755e-02 | 1.357 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 4.393755e-02 | 1.357 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 4.435152e-02 | 1.353 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 4.436013e-02 | 1.353 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 4.436013e-02 | 1.353 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 4.436013e-02 | 1.353 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 4.653320e-02 | 1.332 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 4.693084e-02 | 1.329 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 4.693084e-02 | 1.329 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 4.693084e-02 | 1.329 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 4.693084e-02 | 1.329 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 4.744847e-02 | 1.324 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 4.744847e-02 | 1.324 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 4.815078e-02 | 1.317 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 4.815078e-02 | 1.317 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 4.872475e-02 | 1.312 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 4.901762e-02 | 1.310 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 4.960644e-02 | 1.304 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 4.998674e-02 | 1.301 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 5.013093e-02 | 1.300 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 5.026205e-02 | 1.299 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 5.026205e-02 | 1.299 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 5.026205e-02 | 1.299 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 5.183813e-02 | 1.285 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 5.183813e-02 | 1.285 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 5.183813e-02 | 1.285 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 5.183813e-02 | 1.285 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 5.183813e-02 | 1.285 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 5.303122e-02 | 1.275 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 5.374068e-02 | 1.270 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 5.573223e-02 | 1.254 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 5.573223e-02 | 1.254 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 5.573223e-02 | 1.254 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 5.605541e-02 | 1.251 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 5.605541e-02 | 1.251 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 5.605541e-02 | 1.251 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 5.661262e-02 | 1.247 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 5.670988e-02 | 1.246 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 5.928377e-02 | 1.227 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 6.030359e-02 | 1.220 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 6.047638e-02 | 1.218 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 6.111284e-02 | 1.214 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 6.111284e-02 | 1.214 | 0 | 0 |
| Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) | R-HSA-1299308 | 6.111284e-02 | 1.214 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 6.111284e-02 | 1.214 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 6.119124e-02 | 1.213 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 6.119124e-02 | 1.213 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 6.119124e-02 | 1.213 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 6.119124e-02 | 1.213 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 6.222782e-02 | 1.206 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 6.317952e-02 | 1.199 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 6.399270e-02 | 1.194 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 6.399270e-02 | 1.194 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 6.427689e-02 | 1.192 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 6.482049e-02 | 1.188 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 6.482049e-02 | 1.188 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 6.482049e-02 | 1.188 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 6.613277e-02 | 1.180 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 6.658662e-02 | 1.177 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 7.143593e-02 | 1.146 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 7.143593e-02 | 1.146 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 7.365397e-02 | 1.133 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 7.505465e-02 | 1.125 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 7.697170e-02 | 1.114 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 7.785726e-02 | 1.109 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 7.785726e-02 | 1.109 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 7.785726e-02 | 1.109 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 7.785726e-02 | 1.109 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 7.785726e-02 | 1.109 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 7.785726e-02 | 1.109 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 7.785726e-02 | 1.109 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 7.785726e-02 | 1.109 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 7.785726e-02 | 1.109 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 7.785726e-02 | 1.109 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 7.785726e-02 | 1.109 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 7.834944e-02 | 1.106 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 7.929403e-02 | 1.101 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 7.929403e-02 | 1.101 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 7.929403e-02 | 1.101 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.952603e-02 | 1.099 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.952603e-02 | 1.099 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 8.012520e-02 | 1.096 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 8.030715e-02 | 1.095 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.030715e-02 | 1.095 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 8.030715e-02 | 1.095 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 8.256043e-02 | 1.083 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 8.256043e-02 | 1.083 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 8.751434e-02 | 1.058 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 8.886825e-02 | 1.051 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 8.930140e-02 | 1.049 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 8.958776e-02 | 1.048 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 8.958776e-02 | 1.048 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 8.958776e-02 | 1.048 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 8.958776e-02 | 1.048 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 9.209434e-02 | 1.036 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 9.209434e-02 | 1.036 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 9.209434e-02 | 1.036 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 9.209434e-02 | 1.036 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 9.209434e-02 | 1.036 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 9.209434e-02 | 1.036 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 9.209434e-02 | 1.036 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 9.283860e-02 | 1.032 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 9.295104e-02 | 1.032 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 9.295104e-02 | 1.032 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 9.301320e-02 | 1.031 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.319618e-02 | 1.031 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 9.454513e-02 | 1.024 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 9.454513e-02 | 1.024 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 9.481131e-02 | 1.023 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 9.481131e-02 | 1.023 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 9.481131e-02 | 1.023 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 9.481131e-02 | 1.023 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 1.806385e-01 | 0.743 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.806385e-01 | 0.743 | 0 | 0 |
| RPIA deficiency: failed conversion of RU5P to R5P | R-HSA-6791461 | 1.806385e-01 | 0.743 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 1.806385e-01 | 0.743 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.806385e-01 | 0.743 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 1.806385e-01 | 0.743 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.806385e-01 | 0.743 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 1.806385e-01 | 0.743 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.806385e-01 | 0.743 | 0 | 0 |
| RPIA deficiency: failed conversion of R5P to RU5P | R-HSA-5659996 | 1.806385e-01 | 0.743 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 1.806385e-01 | 0.743 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 1.806385e-01 | 0.743 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 1.806385e-01 | 0.743 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.211044e-01 | 0.917 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.211044e-01 | 0.917 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 1.211044e-01 | 0.917 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.211044e-01 | 0.917 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 1.548307e-01 | 0.810 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.548307e-01 | 0.810 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 9.865655e-02 | 1.006 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 9.865655e-02 | 1.006 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 9.865655e-02 | 1.006 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 1.194315e-01 | 0.923 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.194315e-01 | 0.923 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.194315e-01 | 0.923 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.194315e-01 | 0.923 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 1.900651e-01 | 0.721 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 1.900651e-01 | 0.721 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.900651e-01 | 0.721 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 1.900651e-01 | 0.721 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 1.900651e-01 | 0.721 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 1.416524e-01 | 0.849 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 1.074716e-01 | 0.969 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 1.651166e-01 | 0.782 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.651166e-01 | 0.782 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.651166e-01 | 0.782 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.651166e-01 | 0.782 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.651166e-01 | 0.782 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 1.239182e-01 | 0.907 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 1.239182e-01 | 0.907 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.239182e-01 | 0.907 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 1.073633e-01 | 0.969 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 1.413548e-01 | 0.850 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 1.209816e-01 | 0.917 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.596953e-01 | 0.797 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 1.596953e-01 | 0.797 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 1.596953e-01 | 0.797 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 1.153654e-01 | 0.938 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.788493e-01 | 0.748 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.788493e-01 | 0.748 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 1.788493e-01 | 0.748 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 1.662253e-01 | 0.779 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 1.193393e-01 | 0.923 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 1.073633e-01 | 0.969 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 1.019881e-01 | 0.991 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.664298e-01 | 0.779 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.019881e-01 | 0.991 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 9.876208e-02 | 1.005 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 9.876208e-02 | 1.005 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 1.112265e-01 | 0.954 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 1.112265e-01 | 0.954 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.074716e-01 | 0.969 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 1.239182e-01 | 0.907 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 9.876208e-02 | 1.005 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 1.193393e-01 | 0.923 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 1.403655e-01 | 0.853 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 1.034634e-01 | 0.985 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 1.209816e-01 | 0.917 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 1.193393e-01 | 0.923 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 1.524680e-01 | 0.817 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 1.548307e-01 | 0.810 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 1.900651e-01 | 0.721 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.900651e-01 | 0.721 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.896224e-01 | 0.722 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 1.209816e-01 | 0.917 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 1.347538e-01 | 0.870 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 1.415366e-01 | 0.849 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 1.113343e-01 | 0.953 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.074716e-01 | 0.969 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 1.037628e-01 | 0.984 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.900651e-01 | 0.721 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 1.074716e-01 | 0.969 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 1.433581e-01 | 0.844 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.088460e-01 | 0.963 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 1.499609e-01 | 0.824 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 1.455301e-01 | 0.837 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 9.548908e-02 | 1.020 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.806385e-01 | 0.743 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.806385e-01 | 0.743 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.211044e-01 | 0.917 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 1.194315e-01 | 0.923 | 0 | 0 |
| Proton/oligopeptide cotransporters | R-HSA-427975 | 1.900651e-01 | 0.721 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 1.416524e-01 | 0.849 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.896224e-01 | 0.722 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.896224e-01 | 0.722 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 1.788493e-01 | 0.748 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 1.403655e-01 | 0.853 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.120174e-01 | 0.951 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.194315e-01 | 0.923 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 1.275679e-01 | 0.894 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 1.403655e-01 | 0.853 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.074716e-01 | 0.969 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 1.874062e-01 | 0.727 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 1.073633e-01 | 0.969 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 1.820417e-01 | 0.740 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 1.504585e-01 | 0.823 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.754894e-01 | 0.756 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.310110e-01 | 0.883 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 1.548307e-01 | 0.810 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.900651e-01 | 0.721 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 1.820417e-01 | 0.740 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.897212e-01 | 0.722 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 1.869116e-01 | 0.728 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 1.037628e-01 | 0.984 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 1.209816e-01 | 0.917 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 1.637909e-01 | 0.786 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.625878e-01 | 0.789 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.433581e-01 | 0.844 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.072459e-01 | 0.970 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 1.467962e-01 | 0.833 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 1.826104e-01 | 0.738 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 1.353613e-01 | 0.869 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.117190e-01 | 0.952 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.419408e-01 | 0.848 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.353613e-01 | 0.869 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 1.073633e-01 | 0.969 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 1.037821e-01 | 0.984 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 1.392984e-01 | 0.856 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 1.598190e-01 | 0.796 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 1.209039e-01 | 0.918 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.413548e-01 | 0.850 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 1.926362e-01 | 0.715 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 1.948720e-01 | 0.710 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.969199e-01 | 0.706 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 1.969199e-01 | 0.706 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 1.987232e-01 | 0.702 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 1.987232e-01 | 0.702 | 0 | 0 |
| PKA activation | R-HSA-163615 | 1.987232e-01 | 0.702 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 1.987232e-01 | 0.702 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 1.987232e-01 | 0.702 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.995599e-01 | 0.700 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 1.995599e-01 | 0.700 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.999436e-01 | 0.699 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 2.043509e-01 | 0.690 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 2.067667e-01 | 0.685 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 2.122317e-01 | 0.673 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 2.122317e-01 | 0.673 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 2.122317e-01 | 0.673 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 2.149730e-01 | 0.668 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 2.149730e-01 | 0.668 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 2.149730e-01 | 0.668 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 2.170178e-01 | 0.664 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 2.170178e-01 | 0.664 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 2.192220e-01 | 0.659 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 2.224891e-01 | 0.653 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 2.262189e-01 | 0.645 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 2.262189e-01 | 0.645 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 2.262189e-01 | 0.645 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 2.262189e-01 | 0.645 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 2.279394e-01 | 0.642 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 2.279394e-01 | 0.642 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 2.279394e-01 | 0.642 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 2.291337e-01 | 0.640 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 2.325319e-01 | 0.634 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 2.347306e-01 | 0.629 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 2.347306e-01 | 0.629 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 2.349268e-01 | 0.629 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 2.349268e-01 | 0.629 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 2.402506e-01 | 0.619 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 2.409794e-01 | 0.618 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 2.409794e-01 | 0.618 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 2.409794e-01 | 0.618 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 2.435757e-01 | 0.613 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.493955e-01 | 0.603 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 2.493955e-01 | 0.603 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 2.525324e-01 | 0.598 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 2.548068e-01 | 0.594 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 2.583324e-01 | 0.588 | 0 | 0 |
| Mitochondrial transcription initiation | R-HSA-163282 | 2.583324e-01 | 0.588 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 2.583324e-01 | 0.588 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 2.583324e-01 | 0.588 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 2.583324e-01 | 0.588 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 2.583324e-01 | 0.588 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 2.583324e-01 | 0.588 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5660724 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 2.583324e-01 | 0.588 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.583324e-01 | 0.588 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.583324e-01 | 0.588 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.583324e-01 | 0.588 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.583324e-01 | 0.588 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 2.583324e-01 | 0.588 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5619081 | 2.583324e-01 | 0.588 | 0 | 0 |
| Nef mediated downregulation of CD28 cell surface expression | R-HSA-164939 | 2.583324e-01 | 0.588 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.583324e-01 | 0.588 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.583324e-01 | 0.588 | 0 | 0 |
| NTRK3 as a dependence receptor | R-HSA-9603505 | 2.583324e-01 | 0.588 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.617149e-01 | 0.582 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 2.617149e-01 | 0.582 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.628014e-01 | 0.580 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.628014e-01 | 0.580 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 2.628014e-01 | 0.580 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 2.628014e-01 | 0.580 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 2.628014e-01 | 0.580 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 2.628014e-01 | 0.580 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 2.628014e-01 | 0.580 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 2.628014e-01 | 0.580 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 2.628014e-01 | 0.580 | 0 | 0 |
| SLC-mediated transport of oligopeptides | R-HSA-9959399 | 2.628014e-01 | 0.580 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.628014e-01 | 0.580 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 2.662131e-01 | 0.575 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 2.674629e-01 | 0.573 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 2.674629e-01 | 0.573 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 2.718667e-01 | 0.566 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.718667e-01 | 0.566 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.795021e-01 | 0.554 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 2.795021e-01 | 0.554 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 2.795021e-01 | 0.554 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 2.835229e-01 | 0.547 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 2.835229e-01 | 0.547 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.835229e-01 | 0.547 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 2.835229e-01 | 0.547 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 2.907818e-01 | 0.536 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 2.914261e-01 | 0.535 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 2.942561e-01 | 0.531 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 2.942561e-01 | 0.531 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 2.942561e-01 | 0.531 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 2.948844e-01 | 0.530 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 2.953800e-01 | 0.530 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 2.994066e-01 | 0.524 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 2.994066e-01 | 0.524 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 2.994066e-01 | 0.524 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 2.994066e-01 | 0.524 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 2.994066e-01 | 0.524 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 2.994066e-01 | 0.524 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 2.994066e-01 | 0.524 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 2.994066e-01 | 0.524 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 2.994066e-01 | 0.524 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 3.013574e-01 | 0.521 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 3.055855e-01 | 0.515 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 3.062126e-01 | 0.514 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 3.088724e-01 | 0.510 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 3.088724e-01 | 0.510 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 3.088724e-01 | 0.510 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 3.104464e-01 | 0.508 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 3.110349e-01 | 0.507 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 3.110349e-01 | 0.507 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 3.110349e-01 | 0.507 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 3.110349e-01 | 0.507 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 3.171499e-01 | 0.499 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 3.212043e-01 | 0.493 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 3.212043e-01 | 0.493 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 3.212043e-01 | 0.493 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 3.212043e-01 | 0.493 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 3.240487e-01 | 0.489 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 3.278170e-01 | 0.484 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 3.282861e-01 | 0.484 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 3.282861e-01 | 0.484 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.286634e-01 | 0.483 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 3.286634e-01 | 0.483 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.286634e-01 | 0.483 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 3.286634e-01 | 0.483 | 0 | 0 |
| Defective AHCY causes HMAHCHD | R-HSA-5578997 | 3.286634e-01 | 0.483 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.286634e-01 | 0.483 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 3.286634e-01 | 0.483 | 0 | 0 |
| Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) | R-HSA-5655799 | 3.286634e-01 | 0.483 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.286634e-01 | 0.483 | 0 | 0 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 | R-HSA-5083633 | 3.286634e-01 | 0.483 | 0 | 0 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 | R-HSA-5083629 | 3.286634e-01 | 0.483 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 3.286634e-01 | 0.483 | 0 | 0 |
| Transcription from mitochondrial promoters | R-HSA-75944 | 3.286634e-01 | 0.483 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 3.286634e-01 | 0.483 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.286634e-01 | 0.483 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 3.286634e-01 | 0.483 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 3.286634e-01 | 0.483 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.286634e-01 | 0.483 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 3.292187e-01 | 0.483 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 3.338376e-01 | 0.476 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 3.357015e-01 | 0.474 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 3.357015e-01 | 0.474 | 0 | 0 |
| Hypusine synthesis from eIF5A-lysine | R-HSA-204626 | 3.357015e-01 | 0.474 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 3.357015e-01 | 0.474 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 3.357015e-01 | 0.474 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 3.357015e-01 | 0.474 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 3.357015e-01 | 0.474 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.357015e-01 | 0.474 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 3.379901e-01 | 0.471 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 3.425285e-01 | 0.465 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 3.447966e-01 | 0.462 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 3.456561e-01 | 0.461 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.481660e-01 | 0.458 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 3.481660e-01 | 0.458 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 3.481660e-01 | 0.458 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 3.486307e-01 | 0.458 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.486307e-01 | 0.458 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 3.486307e-01 | 0.458 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 3.501360e-01 | 0.456 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 3.501360e-01 | 0.456 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 3.501360e-01 | 0.456 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 3.557783e-01 | 0.449 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 3.587534e-01 | 0.445 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 3.674920e-01 | 0.435 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 3.681018e-01 | 0.434 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.714161e-01 | 0.430 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 3.714161e-01 | 0.430 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 3.714161e-01 | 0.430 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 3.714161e-01 | 0.430 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 3.714161e-01 | 0.430 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 3.714161e-01 | 0.430 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.714161e-01 | 0.430 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 3.714161e-01 | 0.430 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 3.724656e-01 | 0.429 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 3.750125e-01 | 0.426 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.750125e-01 | 0.426 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 3.750125e-01 | 0.426 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 3.806015e-01 | 0.420 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 3.823300e-01 | 0.418 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 3.866102e-01 | 0.413 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 3.875820e-01 | 0.412 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 3.899196e-01 | 0.409 | 0 | 0 |
| Activated NTRK3 signals through PLCG1 | R-HSA-9034793 | 3.923287e-01 | 0.406 | 0 | 0 |
| PLC-gamma1 signalling | R-HSA-167021 | 3.923287e-01 | 0.406 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.923287e-01 | 0.406 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 3.923287e-01 | 0.406 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.923287e-01 | 0.406 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 3.923287e-01 | 0.406 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 3.923287e-01 | 0.406 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 3.923287e-01 | 0.406 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 3.923287e-01 | 0.406 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 3.923287e-01 | 0.406 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 3.947337e-01 | 0.404 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 3.947337e-01 | 0.404 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 4.016288e-01 | 0.396 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 4.016288e-01 | 0.396 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 4.036516e-01 | 0.394 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 4.053890e-01 | 0.392 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 4.063342e-01 | 0.391 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 4.063342e-01 | 0.391 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 4.063342e-01 | 0.391 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 4.063342e-01 | 0.391 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 4.070236e-01 | 0.390 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 4.070236e-01 | 0.390 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 4.070236e-01 | 0.390 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 4.168731e-01 | 0.380 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 4.263816e-01 | 0.370 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 4.263816e-01 | 0.370 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 4.263816e-01 | 0.370 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 4.263816e-01 | 0.370 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 4.279124e-01 | 0.369 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.279124e-01 | 0.369 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 4.279124e-01 | 0.369 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 4.329976e-01 | 0.364 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 4.329976e-01 | 0.364 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 4.370444e-01 | 0.359 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 4.388221e-01 | 0.358 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 4.388221e-01 | 0.358 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 4.388221e-01 | 0.358 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 4.388221e-01 | 0.358 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 4.388221e-01 | 0.358 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 4.388221e-01 | 0.358 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 4.394357e-01 | 0.357 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 4.402857e-01 | 0.356 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.402857e-01 | 0.356 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 4.402857e-01 | 0.356 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 4.402857e-01 | 0.356 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 4.402857e-01 | 0.356 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 4.499598e-01 | 0.347 | 0 | 0 |
| Activated NTRK2 signals through PLCG1 | R-HSA-9026527 | 4.499598e-01 | 0.347 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 4.499598e-01 | 0.347 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 4.499598e-01 | 0.347 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.499598e-01 | 0.347 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 4.499598e-01 | 0.347 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.499598e-01 | 0.347 | 0 | 0 |
| Extrinsic Pathway of Fibrin Clot Formation | R-HSA-140834 | 4.499598e-01 | 0.347 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 4.499598e-01 | 0.347 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 4.499598e-01 | 0.347 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 4.499598e-01 | 0.347 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 4.499598e-01 | 0.347 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 4.499598e-01 | 0.347 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 4.503240e-01 | 0.346 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.537734e-01 | 0.343 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 4.537734e-01 | 0.343 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 4.537734e-01 | 0.343 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 4.537734e-01 | 0.343 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 4.537734e-01 | 0.343 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 4.537734e-01 | 0.343 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 4.538158e-01 | 0.343 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 4.586924e-01 | 0.338 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 4.605241e-01 | 0.337 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 4.605241e-01 | 0.337 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 4.605241e-01 | 0.337 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 4.605241e-01 | 0.337 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 4.646799e-01 | 0.333 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 4.646799e-01 | 0.333 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 4.731401e-01 | 0.325 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 4.731401e-01 | 0.325 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 4.735158e-01 | 0.325 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 4.766481e-01 | 0.322 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 4.791337e-01 | 0.320 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.791337e-01 | 0.320 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 4.819275e-01 | 0.317 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 4.835437e-01 | 0.316 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 4.862083e-01 | 0.313 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 4.864955e-01 | 0.313 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 4.905765e-01 | 0.309 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 5.003226e-01 | 0.301 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 5.008615e-01 | 0.300 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 5.008615e-01 | 0.300 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 5.008615e-01 | 0.300 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 5.014709e-01 | 0.300 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 5.014709e-01 | 0.300 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 5.021284e-01 | 0.299 | 0 | 0 |
| IRS activation | R-HSA-74713 | 5.021284e-01 | 0.299 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 5.021284e-01 | 0.299 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 5.021284e-01 | 0.299 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 5.021284e-01 | 0.299 | 0 | 0 |
| Defective SLC1A3 causes episodic ataxia 6 (EA6) | R-HSA-5619062 | 5.021284e-01 | 0.299 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 5.021284e-01 | 0.299 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 5.021284e-01 | 0.299 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 5.021284e-01 | 0.299 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 5.021284e-01 | 0.299 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 5.021284e-01 | 0.299 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 5.021284e-01 | 0.299 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 5.021284e-01 | 0.299 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 5.021284e-01 | 0.299 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 5.021284e-01 | 0.299 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 5.021284e-01 | 0.299 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 5.021284e-01 | 0.299 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 5.021284e-01 | 0.299 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 5.021284e-01 | 0.299 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 5.021284e-01 | 0.299 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 5.021709e-01 | 0.299 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 5.021709e-01 | 0.299 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 5.029863e-01 | 0.298 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 5.039265e-01 | 0.298 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 5.039265e-01 | 0.298 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 5.039265e-01 | 0.298 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 5.039265e-01 | 0.298 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 5.048002e-01 | 0.297 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 5.048002e-01 | 0.297 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 5.048002e-01 | 0.297 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 5.048002e-01 | 0.297 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 5.048002e-01 | 0.297 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 5.048002e-01 | 0.297 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 5.162598e-01 | 0.287 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 5.162598e-01 | 0.287 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 5.162598e-01 | 0.287 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 5.162598e-01 | 0.287 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 5.162598e-01 | 0.287 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 5.162598e-01 | 0.287 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 5.205305e-01 | 0.284 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 5.236592e-01 | 0.281 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 5.236592e-01 | 0.281 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 5.280951e-01 | 0.277 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 5.280951e-01 | 0.277 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 5.280951e-01 | 0.277 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 5.351969e-01 | 0.271 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 5.351969e-01 | 0.271 | 0 | 0 |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA | R-HSA-77348 | 5.351969e-01 | 0.271 | 0 | 0 |
| Beta oxidation of hexanoyl-CoA to butanoyl-CoA | R-HSA-77350 | 5.351969e-01 | 0.271 | 0 | 0 |
| Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA | R-HSA-77310 | 5.351969e-01 | 0.271 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 5.351969e-01 | 0.271 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 5.351969e-01 | 0.271 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 5.351969e-01 | 0.271 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 5.351969e-01 | 0.271 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 5.359759e-01 | 0.271 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 5.371981e-01 | 0.270 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 5.385941e-01 | 0.269 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 5.385941e-01 | 0.269 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 5.385941e-01 | 0.269 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.430000e-01 | 0.265 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 5.439099e-01 | 0.264 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.493517e-01 | 0.260 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.493517e-01 | 0.260 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.493517e-01 | 0.260 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 5.493517e-01 | 0.260 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.493517e-01 | 0.260 | 0 | 0 |
| Loss-of-function mutations in DLD cause MSUD3/DLDD | R-HSA-9907570 | 5.493517e-01 | 0.260 | 0 | 0 |
| Loss-of-function mutations in DBT cause MSUD2 | R-HSA-9865113 | 5.493517e-01 | 0.260 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 5.493517e-01 | 0.260 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 5.493517e-01 | 0.260 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 5.493517e-01 | 0.260 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 5.493517e-01 | 0.260 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 5.493517e-01 | 0.260 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 5.493517e-01 | 0.260 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 5.493517e-01 | 0.260 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 5.508365e-01 | 0.259 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 5.515931e-01 | 0.258 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 5.515931e-01 | 0.258 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 5.515931e-01 | 0.258 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 5.515931e-01 | 0.258 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 5.563362e-01 | 0.255 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 5.563362e-01 | 0.255 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 5.569058e-01 | 0.254 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 5.642851e-01 | 0.249 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 5.667943e-01 | 0.247 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 5.706294e-01 | 0.244 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 5.715942e-01 | 0.243 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 5.737339e-01 | 0.241 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 5.743825e-01 | 0.241 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 5.830225e-01 | 0.234 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 5.830225e-01 | 0.234 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 5.830225e-01 | 0.234 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 5.841589e-01 | 0.233 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 5.920396e-01 | 0.228 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 5.920396e-01 | 0.228 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 5.920396e-01 | 0.228 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 5.920396e-01 | 0.228 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 5.920396e-01 | 0.228 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 5.920985e-01 | 0.228 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 5.920985e-01 | 0.228 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.920985e-01 | 0.228 | 0 | 0 |
| Chylomicron clearance | R-HSA-8964026 | 5.920985e-01 | 0.228 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 5.920985e-01 | 0.228 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.920985e-01 | 0.228 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.920985e-01 | 0.228 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 5.920985e-01 | 0.228 | 0 | 0 |
| Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD | R-HSA-9865125 | 5.920985e-01 | 0.228 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 5.920985e-01 | 0.228 | 0 | 0 |
| Branched-chain ketoacid dehydrogenase kinase deficiency | R-HSA-9912481 | 5.920985e-01 | 0.228 | 0 | 0 |
| H139Hfs13* PPM1K causes a mild variant of MSUD | R-HSA-9912529 | 5.920985e-01 | 0.228 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 5.920985e-01 | 0.228 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 5.920985e-01 | 0.228 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.920985e-01 | 0.228 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 5.920985e-01 | 0.228 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 5.920985e-01 | 0.228 | 0 | 0 |
| Leukotriene receptors | R-HSA-391906 | 5.920985e-01 | 0.228 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.920985e-01 | 0.228 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 5.964338e-01 | 0.224 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 5.964338e-01 | 0.224 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 5.964338e-01 | 0.224 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 5.964338e-01 | 0.224 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 5.964338e-01 | 0.224 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 5.964338e-01 | 0.224 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 5.964338e-01 | 0.224 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 5.964338e-01 | 0.224 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 6.040280e-01 | 0.219 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 6.050469e-01 | 0.218 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 6.066195e-01 | 0.217 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 6.074182e-01 | 0.217 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 6.085554e-01 | 0.216 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 6.111230e-01 | 0.214 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 6.177250e-01 | 0.209 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 6.177250e-01 | 0.209 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 6.177250e-01 | 0.209 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 6.184517e-01 | 0.209 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 6.184517e-01 | 0.209 | 0 | 0 |
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA | R-HSA-77346 | 6.184517e-01 | 0.209 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 6.184517e-01 | 0.209 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 6.184517e-01 | 0.209 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 6.184517e-01 | 0.209 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 6.184517e-01 | 0.209 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 6.184517e-01 | 0.209 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 6.201237e-01 | 0.208 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 6.201237e-01 | 0.208 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 6.201237e-01 | 0.208 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 6.201237e-01 | 0.208 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 6.234763e-01 | 0.205 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 6.236720e-01 | 0.205 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 6.307927e-01 | 0.200 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 6.307927e-01 | 0.200 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.307927e-01 | 0.200 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 6.307927e-01 | 0.200 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 6.307927e-01 | 0.200 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 6.307927e-01 | 0.200 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 6.307927e-01 | 0.200 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 6.307927e-01 | 0.200 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 6.307927e-01 | 0.200 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 6.307927e-01 | 0.200 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.307927e-01 | 0.200 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 6.307927e-01 | 0.200 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 6.307927e-01 | 0.200 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 6.307927e-01 | 0.200 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 6.307927e-01 | 0.200 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 6.307927e-01 | 0.200 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 6.307927e-01 | 0.200 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 6.318847e-01 | 0.199 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 6.382406e-01 | 0.195 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 6.382406e-01 | 0.195 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 6.382406e-01 | 0.195 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 6.382406e-01 | 0.195 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 6.382406e-01 | 0.195 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 6.382406e-01 | 0.195 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 6.382406e-01 | 0.195 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 6.382406e-01 | 0.195 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 6.382406e-01 | 0.195 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 6.435263e-01 | 0.191 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 6.435263e-01 | 0.191 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 6.435263e-01 | 0.191 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 6.435263e-01 | 0.191 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 6.445127e-01 | 0.191 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 6.549390e-01 | 0.184 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 6.550770e-01 | 0.184 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 6.550770e-01 | 0.184 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.561949e-01 | 0.183 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 6.579714e-01 | 0.182 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 6.579714e-01 | 0.182 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 6.579714e-01 | 0.182 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 6.592783e-01 | 0.181 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.658184e-01 | 0.177 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.658184e-01 | 0.177 | 0 | 0 |
| RSK activation | R-HSA-444257 | 6.658184e-01 | 0.177 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 6.658184e-01 | 0.177 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.658184e-01 | 0.177 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 6.658184e-01 | 0.177 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 6.658184e-01 | 0.177 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 6.658184e-01 | 0.177 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 6.658184e-01 | 0.177 | 0 | 0 |
| Fructose biosynthesis | R-HSA-5652227 | 6.658184e-01 | 0.177 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.658184e-01 | 0.177 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 6.658184e-01 | 0.177 | 0 | 0 |
| SLC-mediated bile acid transport | R-HSA-9958517 | 6.658184e-01 | 0.177 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.658184e-01 | 0.177 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 6.672794e-01 | 0.176 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 6.672794e-01 | 0.176 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 6.672794e-01 | 0.176 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 6.672794e-01 | 0.176 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 6.672794e-01 | 0.176 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 6.672794e-01 | 0.176 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 6.672794e-01 | 0.176 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 6.699302e-01 | 0.174 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 6.699302e-01 | 0.174 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 6.699302e-01 | 0.174 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 6.699302e-01 | 0.174 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 6.717212e-01 | 0.173 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 6.717212e-01 | 0.173 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 6.762726e-01 | 0.170 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 6.769135e-01 | 0.169 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 6.833113e-01 | 0.165 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 6.833916e-01 | 0.165 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 6.844919e-01 | 0.165 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 6.878022e-01 | 0.163 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 6.878022e-01 | 0.163 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 6.880959e-01 | 0.162 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 6.897360e-01 | 0.161 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.897360e-01 | 0.161 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 6.897360e-01 | 0.161 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 6.897360e-01 | 0.161 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 6.950678e-01 | 0.158 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 6.950678e-01 | 0.158 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 6.950678e-01 | 0.158 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 6.950678e-01 | 0.158 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 6.955237e-01 | 0.158 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 6.975232e-01 | 0.156 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 6.975232e-01 | 0.156 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 6.975232e-01 | 0.156 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 6.975232e-01 | 0.156 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 6.975232e-01 | 0.156 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.975232e-01 | 0.156 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 6.975232e-01 | 0.156 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 6.975232e-01 | 0.156 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 6.975232e-01 | 0.156 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.975232e-01 | 0.156 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 6.975232e-01 | 0.156 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.975232e-01 | 0.156 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 6.975232e-01 | 0.156 | 0 | 0 |
| Expression of NOTCH2NL genes | R-HSA-9911233 | 6.975232e-01 | 0.156 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 6.975232e-01 | 0.156 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 6.975232e-01 | 0.156 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 6.975232e-01 | 0.156 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 6.975232e-01 | 0.156 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 6.975232e-01 | 0.156 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 6.986108e-01 | 0.156 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 6.986267e-01 | 0.156 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 7.011067e-01 | 0.154 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.027923e-01 | 0.153 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 7.033176e-01 | 0.153 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 7.069514e-01 | 0.151 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 7.069514e-01 | 0.151 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 7.089931e-01 | 0.149 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 7.109284e-01 | 0.148 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 7.109284e-01 | 0.148 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 7.109284e-01 | 0.148 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 7.109284e-01 | 0.148 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 7.124392e-01 | 0.147 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 7.182671e-01 | 0.144 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 7.182671e-01 | 0.144 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 7.262218e-01 | 0.139 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 7.262218e-01 | 0.139 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 7.262218e-01 | 0.139 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 7.262218e-01 | 0.139 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 7.262218e-01 | 0.139 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 7.262218e-01 | 0.139 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 7.262218e-01 | 0.139 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 7.262218e-01 | 0.139 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 7.262218e-01 | 0.139 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 7.290366e-01 | 0.137 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 7.308942e-01 | 0.136 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 7.308942e-01 | 0.136 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 7.308942e-01 | 0.136 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 7.308942e-01 | 0.136 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 7.308942e-01 | 0.136 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 7.308942e-01 | 0.136 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 7.326530e-01 | 0.135 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 7.338387e-01 | 0.134 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 7.338387e-01 | 0.134 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 7.371025e-01 | 0.132 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 7.448717e-01 | 0.128 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 7.496754e-01 | 0.125 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 7.496754e-01 | 0.125 | 0 | 0 |
| DAG1 core M3 glycosylations | R-HSA-8932505 | 7.521990e-01 | 0.124 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.521990e-01 | 0.124 | 0 | 0 |
| Conjugation of benzoate with glycine | R-HSA-177135 | 7.521990e-01 | 0.124 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 7.521990e-01 | 0.124 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 7.521990e-01 | 0.124 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.521990e-01 | 0.124 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.521990e-01 | 0.124 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 7.521990e-01 | 0.124 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.521990e-01 | 0.124 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.544584e-01 | 0.122 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 7.559754e-01 | 0.121 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 7.597527e-01 | 0.119 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 7.599590e-01 | 0.119 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 7.599590e-01 | 0.119 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 7.618114e-01 | 0.118 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 7.673169e-01 | 0.115 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 7.673169e-01 | 0.115 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 7.673169e-01 | 0.115 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 7.673169e-01 | 0.115 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 7.740356e-01 | 0.111 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 7.743155e-01 | 0.111 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 7.743155e-01 | 0.111 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 7.752079e-01 | 0.111 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 7.753867e-01 | 0.110 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.757128e-01 | 0.110 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 7.757128e-01 | 0.110 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 7.757128e-01 | 0.110 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.757128e-01 | 0.110 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 7.757128e-01 | 0.110 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.757128e-01 | 0.110 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 7.757128e-01 | 0.110 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 7.757128e-01 | 0.110 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 7.757128e-01 | 0.110 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 7.763888e-01 | 0.110 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 7.831772e-01 | 0.106 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 7.831772e-01 | 0.106 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 7.831772e-01 | 0.106 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 7.838659e-01 | 0.106 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.838659e-01 | 0.106 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 7.838659e-01 | 0.106 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 7.846709e-01 | 0.105 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 7.846709e-01 | 0.105 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 7.846709e-01 | 0.105 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 7.850793e-01 | 0.105 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 7.956995e-01 | 0.099 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 7.969966e-01 | 0.099 | 0 | 0 |
| Maple Syrup Urine Disease | R-HSA-9865114 | 7.969966e-01 | 0.099 | 0 | 0 |
| Beta oxidation of myristoyl-CoA to lauroyl-CoA | R-HSA-77285 | 7.969966e-01 | 0.099 | 0 | 0 |
| Beta oxidation of palmitoyl-CoA to myristoyl-CoA | R-HSA-77305 | 7.969966e-01 | 0.099 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 7.969966e-01 | 0.099 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 7.969966e-01 | 0.099 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 7.969966e-01 | 0.099 | 0 | 0 |
| Acetylation | R-HSA-156582 | 7.969966e-01 | 0.099 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.969966e-01 | 0.099 | 0 | 0 |
| Conjugation of salicylate with glycine | R-HSA-177128 | 7.969966e-01 | 0.099 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.969966e-01 | 0.099 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.969966e-01 | 0.099 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 7.969966e-01 | 0.099 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 7.969966e-01 | 0.099 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 7.969966e-01 | 0.099 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 7.969966e-01 | 0.099 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 7.969966e-01 | 0.099 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 7.969966e-01 | 0.099 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.969966e-01 | 0.099 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.993708e-01 | 0.097 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 7.993708e-01 | 0.097 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 8.074850e-01 | 0.093 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 8.138807e-01 | 0.089 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 8.138807e-01 | 0.089 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 8.138807e-01 | 0.089 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 8.138807e-01 | 0.089 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 8.138807e-01 | 0.089 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 8.162618e-01 | 0.088 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.162618e-01 | 0.088 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 8.162618e-01 | 0.088 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.170942e-01 | 0.088 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 8.250927e-01 | 0.083 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 8.274448e-01 | 0.082 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 8.274448e-01 | 0.082 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.274448e-01 | 0.082 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 8.274448e-01 | 0.082 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.274448e-01 | 0.082 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 8.291516e-01 | 0.081 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 8.329840e-01 | 0.079 | 0 | 0 |
| BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV | R-HSA-9859138 | 8.336998e-01 | 0.079 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 8.336998e-01 | 0.079 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.336998e-01 | 0.079 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 8.336998e-01 | 0.079 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 8.336998e-01 | 0.079 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.336998e-01 | 0.079 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 8.336998e-01 | 0.079 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.336998e-01 | 0.079 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 8.358342e-01 | 0.078 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 8.384590e-01 | 0.077 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 8.390559e-01 | 0.076 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.401119e-01 | 0.076 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.401119e-01 | 0.076 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 8.427159e-01 | 0.074 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 8.458421e-01 | 0.073 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 8.479243e-01 | 0.072 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 8.494837e-01 | 0.071 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 8.494837e-01 | 0.071 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 8.494837e-01 | 0.071 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.494837e-01 | 0.071 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 8.494837e-01 | 0.071 | 0 | 0 |
| Beta oxidation of butanoyl-CoA to acetyl-CoA | R-HSA-77352 | 8.494837e-01 | 0.071 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 8.494837e-01 | 0.071 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 8.494837e-01 | 0.071 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 8.494837e-01 | 0.071 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 8.494837e-01 | 0.071 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 8.519299e-01 | 0.070 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 8.559627e-01 | 0.068 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 8.616575e-01 | 0.065 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 8.628083e-01 | 0.064 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 8.629460e-01 | 0.064 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 8.637704e-01 | 0.064 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.637704e-01 | 0.064 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.637704e-01 | 0.064 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.637704e-01 | 0.064 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 8.637704e-01 | 0.064 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 8.637704e-01 | 0.064 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 8.637704e-01 | 0.064 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 8.637704e-01 | 0.064 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 8.637704e-01 | 0.064 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 8.637704e-01 | 0.064 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.637704e-01 | 0.064 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 8.637704e-01 | 0.064 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 8.653420e-01 | 0.063 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 8.653420e-01 | 0.063 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 8.722252e-01 | 0.059 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 8.732058e-01 | 0.059 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 8.732058e-01 | 0.059 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.732058e-01 | 0.059 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 8.732058e-01 | 0.059 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 8.765630e-01 | 0.057 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 8.767018e-01 | 0.057 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.767018e-01 | 0.057 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of unsaturated fatty acids | R-HSA-77288 | 8.767018e-01 | 0.057 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 8.767018e-01 | 0.057 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 8.767018e-01 | 0.057 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.767018e-01 | 0.057 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 8.790751e-01 | 0.056 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 8.799076e-01 | 0.056 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 8.827536e-01 | 0.054 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 8.884064e-01 | 0.051 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.884064e-01 | 0.051 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.884064e-01 | 0.051 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.884064e-01 | 0.051 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.884064e-01 | 0.051 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 8.884064e-01 | 0.051 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 8.884064e-01 | 0.051 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 8.884064e-01 | 0.051 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 8.900744e-01 | 0.051 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 8.916321e-01 | 0.050 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 8.932040e-01 | 0.049 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 8.990005e-01 | 0.046 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 8.990005e-01 | 0.046 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 8.990005e-01 | 0.046 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 8.990005e-01 | 0.046 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 8.990005e-01 | 0.046 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 8.998823e-01 | 0.046 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 8.998823e-01 | 0.046 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.075434e-01 | 0.042 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.075434e-01 | 0.042 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.075434e-01 | 0.042 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.075434e-01 | 0.042 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 9.085894e-01 | 0.042 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 9.085894e-01 | 0.042 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 9.085894e-01 | 0.042 | 0 | 0 |
| Amino Acid conjugation | R-HSA-156587 | 9.085894e-01 | 0.042 | 0 | 0 |
| Conjugation of carboxylic acids | R-HSA-159424 | 9.085894e-01 | 0.042 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.085894e-01 | 0.042 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 9.085894e-01 | 0.042 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 9.085894e-01 | 0.042 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 9.085894e-01 | 0.042 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 9.085894e-01 | 0.042 | 0 | 0 |
| HDL remodeling | R-HSA-8964058 | 9.085894e-01 | 0.042 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 9.101448e-01 | 0.041 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.140808e-01 | 0.039 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.146529e-01 | 0.039 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.152438e-01 | 0.038 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.166983e-01 | 0.038 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 9.172532e-01 | 0.038 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 9.172532e-01 | 0.038 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 9.172685e-01 | 0.038 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 9.172685e-01 | 0.038 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.172685e-01 | 0.038 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.172685e-01 | 0.038 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.172685e-01 | 0.038 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.172685e-01 | 0.038 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.212464e-01 | 0.036 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.214524e-01 | 0.036 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.251239e-01 | 0.034 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.251239e-01 | 0.034 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.251239e-01 | 0.034 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 9.251239e-01 | 0.034 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.251239e-01 | 0.034 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.251239e-01 | 0.034 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.273579e-01 | 0.033 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.276767e-01 | 0.033 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.319780e-01 | 0.031 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.322340e-01 | 0.030 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.322340e-01 | 0.030 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.322340e-01 | 0.030 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 9.330193e-01 | 0.030 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 9.382610e-01 | 0.028 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 9.386692e-01 | 0.027 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 9.386692e-01 | 0.027 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 9.386692e-01 | 0.027 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 9.386692e-01 | 0.027 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 9.386692e-01 | 0.027 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.386692e-01 | 0.027 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.386692e-01 | 0.027 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.435528e-01 | 0.025 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.436486e-01 | 0.025 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.436486e-01 | 0.025 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.444937e-01 | 0.025 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.444937e-01 | 0.025 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 9.444937e-01 | 0.025 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.444937e-01 | 0.025 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.444937e-01 | 0.025 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.444937e-01 | 0.025 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.444937e-01 | 0.025 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.444937e-01 | 0.025 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 9.475982e-01 | 0.023 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 9.475982e-01 | 0.023 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.475982e-01 | 0.023 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.475982e-01 | 0.023 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 9.475982e-01 | 0.023 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.476362e-01 | 0.023 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.497653e-01 | 0.022 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.497653e-01 | 0.022 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 9.497653e-01 | 0.022 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.497653e-01 | 0.022 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.497653e-01 | 0.022 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.517460e-01 | 0.021 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.545366e-01 | 0.020 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.555790e-01 | 0.020 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.579049e-01 | 0.019 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 9.588550e-01 | 0.018 | 0 | 0 |
| Diseases of branched-chain amino acid catabolism | R-HSA-9865118 | 9.588550e-01 | 0.018 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.588550e-01 | 0.018 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.588550e-01 | 0.018 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.624367e-01 | 0.017 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 9.627634e-01 | 0.016 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.629054e-01 | 0.016 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.654056e-01 | 0.015 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 9.663007e-01 | 0.015 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids | R-HSA-77286 | 9.681891e-01 | 0.014 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.695022e-01 | 0.013 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.695022e-01 | 0.013 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 9.695022e-01 | 0.013 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.695022e-01 | 0.013 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.695022e-01 | 0.013 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.699920e-01 | 0.013 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 9.723997e-01 | 0.012 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.731229e-01 | 0.012 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.750221e-01 | 0.011 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.752644e-01 | 0.011 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.771684e-01 | 0.010 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.773134e-01 | 0.010 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.773955e-01 | 0.010 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 9.791642e-01 | 0.009 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.795435e-01 | 0.009 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.808682e-01 | 0.008 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.810025e-01 | 0.008 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.812860e-01 | 0.008 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.832468e-01 | 0.007 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.832468e-01 | 0.007 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 9.832468e-01 | 0.007 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.837233e-01 | 0.007 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.837233e-01 | 0.007 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.838798e-01 | 0.007 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.848391e-01 | 0.007 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.848391e-01 | 0.007 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.848391e-01 | 0.007 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.862801e-01 | 0.006 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.864543e-01 | 0.006 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.875842e-01 | 0.005 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.875842e-01 | 0.005 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.875842e-01 | 0.005 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.885831e-01 | 0.005 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 9.885831e-01 | 0.005 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 9.906744e-01 | 0.004 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.907991e-01 | 0.004 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.913144e-01 | 0.004 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.913144e-01 | 0.004 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 9.919379e-01 | 0.004 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.919379e-01 | 0.004 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.924656e-01 | 0.003 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.926127e-01 | 0.003 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 9.938005e-01 | 0.003 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 9.938005e-01 | 0.003 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 9.943221e-01 | 0.002 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.944170e-01 | 0.002 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.944170e-01 | 0.002 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.948005e-01 | 0.002 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.952394e-01 | 0.002 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.952394e-01 | 0.002 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.955746e-01 | 0.002 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.959384e-01 | 0.002 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.961216e-01 | 0.002 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.966591e-01 | 0.001 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.966591e-01 | 0.001 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.966591e-01 | 0.001 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.969351e-01 | 0.001 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.969585e-01 | 0.001 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.972035e-01 | 0.001 | 0 | 0 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 9.972267e-01 | 0.001 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.974420e-01 | 0.001 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.979454e-01 | 0.001 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.981450e-01 | 0.001 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.982113e-01 | 0.001 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.982202e-01 | 0.001 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.983080e-01 | 0.001 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.983178e-01 | 0.001 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.985093e-01 | 0.001 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.985241e-01 | 0.001 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.986737e-01 | 0.001 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.988725e-01 | 0.000 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.988725e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.989333e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.989682e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.990281e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.991648e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.992179e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.992443e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.992443e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.994936e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.994950e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.995212e-01 | 0.000 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.995796e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.996034e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.996163e-01 | 0.000 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.996163e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.996250e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.997487e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.997560e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.997790e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.997979e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.998139e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.998237e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.998316e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.998316e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.998622e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.998622e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.998980e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999245e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999333e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999392e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999418e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999420e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999596e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.999773e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999778e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999893e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999937e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999959e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999967e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999989e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999991e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999991e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999996e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999996e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999997e-01 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 9.999999e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999999e-01 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 9.999999e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
