NEK1

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities

T Sites Probabilities

Y Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Log-Odds: Y Sites / Y Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

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substrate_uniprot site source substrate_genes site_seq
A5A3E0 S939 Sugiyama POTEF A26C1B VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE
A6NMY6 S134 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD
A6NMY6 T123 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B LKtPAQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEI
A6NMY6 T136 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B AsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtDLE
A6NMY6 T163 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
O00161 S23 Sugiyama SNAP23 NLssEEIQQRAHQITDEsLEstRRILGLAIEsQDAGIKtIt
O00273 S302 Sugiyama DFFA DFF1 DFF45 H13 TETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDLQN
O00273 T300 Sugiyama DFFA DFF1 DFF45 H13 KKTETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDL
O14777 S165 EPSD|PSP NDC80 HEC HEC1 KNTC2 TKFEEEVPRIFKDLGYPFALsKSSMYTVGAPHTWPHIVAAL
O14908 T238 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 FDMISQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPs
O14908 T242 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 SQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPsAFEE
O14950 T160 Sugiyama MYL12B MRLC2 MYLC2B DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
O15127 T109 Sugiyama SCAMP2 QEELDRKAAELERKERELQNtVANLHVRQNNWPPLPSWCPV
O15212 S53 Sugiyama PFDN6 HKE2 PFD6 LEAQLtENNIVKEELALLDGsNVVFKLLGPVLVKQELGEAR
O15212 T107 Sugiyama PFDN6 HKE2 PFD6 IKRYESQLRDLERQsEQQREtLAQLQQEFQRAQAAKAGAPG
O15347 S14 Sugiyama HMGB3 HMG2A HMG4 _______MAKGDPKKPKGKMsAYAFFVQtCREEHKKKNPEV
O15347 T22 Sugiyama HMGB3 HMG2A HMG4 AKGDPKKPKGKMsAYAFFVQtCREEHKKKNPEVPVNFAEFS
O15446 S64 Sugiyama POLR1G ASE1 CAST CD3EAP PAF49 LIQAPADFAPECFNGRHVPLsGsQIVKGKLAGKRHRyRVLS
O43175 T78 Sugiyama PHGDH PGDH3 KVTADVINAAEKLQVVGRAGtGVDNVDLEAAtRKGILVMNT
O43175 T89 Sugiyama PHGDH PGDH3 KLQVVGRAGtGVDNVDLEAAtRKGILVMNTPNGNSLSAAEL
O43390 T134 Sugiyama HNRNPR HNRPR KVQESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O43390 T141 Sugiyama HNRNPR HNRPR GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP
O43390 Y136 Sugiyama HNRNPR HNRPR QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O43399 S84 Sugiyama TPD52L2 RQVLAAKERHCGELKRRLGLstLGELKQNLsRsWHDVQVss
O43399 T85 Sugiyama TPD52L2 QVLAAKERHCGELKRRLGLstLGELKQNLsRsWHDVQVssA
O43707 T359 Sugiyama ACTN4 RRVHKPPKVQEKCQLEINFNtLQtKLRLSNRPAFMPSEGKM
O43707 T362 Sugiyama ACTN4 HKPPKVQEKCQLEINFNtLQtKLRLSNRPAFMPSEGKMVSD
O43707 T613 Sugiyama ACTN4 EAQRIAESNHIKLsGsNPyttVtPQIINsKWEKVQQLVPKR
O43852 T196 Sugiyama CALU FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60220 S94 Sugiyama TIMM8A DDP DDP1 TIM8A SQFILNRLEQTQKSKPVFSEsLsD_________________
O60271 T191 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 MEHLERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPA
O60271 T418 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 DEGADLLGMGREVENLILENtQLLEtKNALNIVKNDLIAKV
O60271 T423 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 LLGMGREVENLILENtQLLEtKNALNIVKNDLIAKVDELTC
O60361 T88 Sugiyama NME2P1 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
O60506 T131 Sugiyama SYNCRIP HNRPQ NSAP1 KVADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDS
O60506 T138 Sugiyama SYNCRIP HNRPQ NSAP1 GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP
O60506 Y133 Sugiyama SYNCRIP HNRPQ NSAP1 ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O60814 S39 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
O60841 S196 Sugiyama EIF5B IF2 KIAA0741 ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN
O60841 T289 Sugiyama EIF5B IF2 KIAA0741 QKESQRKFEEETVKSKVTVDtGVIPAsEEKAEtPtAAEDDN
O75116 T573 Sugiyama ROCK2 KIAA0619 STEKVNQLQRQLDEtNALLRtESDTAARLRKTQAESSKQIQ
O75534 T761 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR GPKAVAAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDN
O95071 T119 Sugiyama UBR5 EDD EDD1 HYD KIAA0896 GRTSRPGRTSDsPWFLsGSEtLGRLAGNTLGSRWSsGVGGs
O95218 S188 Sugiyama ZRANB2 ZIS ZNF265 KLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRRSRSKSRS
O95218 T50 Sugiyama ZRANB2 ZIS ZNF265 SCNRCGREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQ
O95218 T55 Sugiyama ZRANB2 ZIS ZNF265 GREKTTEAKMMKAGGtEIGKtLAEKSRGLFsANDWQCKTCs
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338 S319 Sugiyama LDHA PIG19 GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00491 T177 Sugiyama PNP NP DRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVAG
P00505 T192 Sugiyama GOT2 KYAT4 AGMQLQGyRYYDPKtCGFDFtGAVEDISKIPEQSVLLLHAC
P00558 S393 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA
P00558 S399 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 T394 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 GDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDAL
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P04040 S515 Sugiyama CAT ALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL________
P04040 T511 Sugiyama CAT SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 T119 Sugiyama ALDOA ALDA KsKGGVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYK
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04075 T49 Sugiyama ALDOA ALDA GILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDR
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04083 T169 Sugiyama ANXA1 ANX1 LPC1 IRDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRs
P04083 T172 Sugiyama ANXA1 ANX1 LPC1 INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF
P04406 S151 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 FVMGVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIV
P04406 S312 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA
P04406 S321 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406 T154 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GVNHEKYDNSLKIIsNAsCttNCLAPLAKVIHDNFGIVEGL
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04632 T143 Sugiyama CAPNS1 CAPN4 CAPNS ILNKVVTRHPDLKTDGFGIDtCRSMVAVMDSDTTGKLGFEE
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P04792 T174 Sugiyama HSPB1 HSP27 HSP28 SSsLsPEGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGP
P04792 T180 Sugiyama HSPB1 HSP27 HSP28 EGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsD
P04792 T184 Sugiyama HSPB1 HSP27 HSP28 TVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAA
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05455 T302 Sugiyama SSB ALGKAKDANNGNLQLRNKEVtWEVLEGEVEKEALKKIIEDQ
P06703 S46 Sugiyama S100A6 CACY KHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRNKDQ
P06703 T43 Sugiyama S100A6 CACY EGDKHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRN
P06733 S268 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP
P06733 S27 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733 S272 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 FRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsI
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 S40 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK
P06733 S419 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 CRSERLAKyNQLLRIEEELGsKAKFAGRNFRNPLAK_____
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T229 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DEGGFAPNILENKEGLELLKtAIGKAGYTDKVVIGMDVAAS
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 T55 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP
P06733 Y270 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV
P06733 Y407 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GLCtGQIKTGAPCRSERLAKyNQLLRIEEELGsKAKFAGRN
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06748 S137 Sugiyama NPM1 NPM VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK
P06748 S260 Sugiyama NPM1 NPM GPssVEDIKAKMQAsIEKGGsLPKVEAKFINyVKNCFRMtD
P06748 T279 Sugiyama NPM1 NPM GsLPKVEAKFINyVKNCFRMtDQEAIQDLWQWRKsL_____
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 S44 Sugiyama LDHB ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM
P07195 T302 Sugiyama LDHB YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 S393 Sugiyama PGK2 PGKB GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA
P07205 S399 Sugiyama PGK2 PGKB CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 T394 Sugiyama PGK2 PGKB GDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEAL
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 T428 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB DKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFPA
P07355 S134 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD
P07355 T123 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D LKtPAQyDAsELKAsMKGLGtDEDsLIEIICsRtNQELQEI
P07355 T136 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D AsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtDLE
P07355 T163 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
P07437 S115 Sugiyama TUBB TUBB5 OK/SW-cl.56 sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 T312 Sugiyama TUBB TUBB5 OK/SW-cl.56 QVFDAKNMMAACDPRHGRyLtVAAVFRGRMsMKEVDEQMLN
P07437 T55 Sugiyama TUBB TUBB5 OK/SW-cl.56 tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs
P07437 Y310 Sugiyama TUBB TUBB5 OK/SW-cl.56 tQQVFDAKNMMAACDPRHGRyLtVAAVFRGRMsMKEVDEQM
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 S739 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV
P07814 T745 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAVQGDVVR
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900 T109 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LtIVDtGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
P07900 T195 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG
P07900 T317 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07900 Y627 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA TANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIEtLR
P07942 S1294 Sugiyama LAMB1 TTSQSNSTAKELDSLQTEAEsLDNtVKELAEQLEFIKNSDI
P07942 T1298 Sugiyama LAMB1 SNSTAKELDSLQTEAEsLDNtVKELAEQLEFIKNSDIRGAL
P08134 T60 Sugiyama RHOC ARH9 ARHC ENYIADIEVDGKQVELALWDtAGQEDYDRLRPLSYPDTDVI
P08195 S598 Sugiyama SLC3A2 MDU1 LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP
P08195 T599 Sugiyama SLC3A2 MDU1 QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH
P08238 S45 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL
P08238 S460 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 T104 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LtLVDtGIGMtKADLINNLGtIAKSGtKAFMEALQAGADIS
P08238 T190 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
P08238 T309 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238 T459 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEt
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08708 T102 Sugiyama RPS17 RPS17L DNyVPEVsALDQEIIEVDPDtKEMLKLLDFGsLsNLQVtQP
P08758 S37 Sugiyama ANXA5 ANX5 ENX2 PP4 ERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAF
P08758 S46 Sugiyama ANXA5 ANX5 ENX2 PP4 KAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTLFGRDLL
P08758 T33 Sugiyama ANXA5 ANX5 ENX2 PP4 PGFDERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEI
P08758 T43 Sugiyama ANXA5 ANX5 ENX2 PP4 tLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTLFGR
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09104 S40 Sugiyama ENO2 VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P09972 T123 Sugiyama ALDOC ALDC IVVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGA
P0DPH7 S48 Sugiyama TUBA3C TUBA2 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P0DPH7 T334 Sugiyama TUBA3C TUBA2 ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
P0DPH7 T41 Sugiyama TUBA3C TUBA2 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P0DPH7 T56 Sugiyama TUBA3C TUBA2 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
P10412 S36 Sugiyama H1-4 H1F4 HIST1H1E EKtPVKKKARKsAGAAKRKAsGPPVsELItKAVAASKERsG
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10412 S58 Sugiyama H1-4 H1F4 HIST1H1E PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P10412 T45 Sugiyama H1-4 H1F4 HIST1H1E RKsAGAAKRKAsGPPVsELItKAVAASKERsGVsLAALKKA
P10412 T92 Sugiyama H1-4 H1F4 HIST1H1E DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P10412 T96 Sugiyama H1-4 H1F4 HIST1H1E NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P10412 T99 Sugiyama H1-4 H1F4 HIST1H1E RIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEAKPK
P10412 Y71 Sugiyama H1-4 H1F4 HIST1H1E SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P10809 S247 Sugiyama HSPD1 HSP60 yFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEIANAH
P10809 S453 Sugiyama HSPD1 HSP60 EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK
P10809 T428 Sugiyama HSPD1 HSP60 GtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGCALLRCI
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P11047 S942 Sugiyama LAMC1 LAMB2 GFYNLQSGQGCERCDCHALGstNGQCDIRTGQCECQPGITG
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T37 Sugiyama HSPA8 HSC70 HSP73 HSPA10 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P11142 T47 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV
P11142 T586 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DKQKILDKCNEIINWLDKNQtAEKEEFEHQQKELEKVCNPI
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P12004 S172 Sugiyama PCNA sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE
P12109 S201 Sugiyama COL6A1 HLGVKVFSVAITPDHLEPRLsIIAtDHTYRRNFTAADWGQS
P12109 T205 Sugiyama COL6A1 KVFSVAITPDHLEPRLsIIAtDHTYRRNFTAADWGQSRDAE
P12814 T340 Sugiyama ACTN1 RRLHKPPKVQEKCQLEINFNtLQtKLRLsNRPAFMPsEGRM
P12814 T343 Sugiyama ACTN1 HKPPKVQEKCQLEINFNtLQtKLRLsNRPAFMPsEGRMVSD
P13667 T380 Sugiyama PDIA4 ERP70 ERP72 PEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGHR
P13674 T140 Sugiyama P4HA1 P4HA YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P13929 S40 Sugiyama ENO3 VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P13987 T76 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF
P14314 S445 Sugiyama PRKCSH G19P1 YRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKy
P14314 S451 Sugiyama PRKCSH G19P1 KLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKyEQGtGC
P14314 S478 Sugiyama PRKCSH G19P1 DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS
P14314 T134 Sugiyama PRKCSH G19P1 NtCKEKGRKEREsLQQMAEVtREGFRLKKILIEDWKKAREE
P14314 T444 Sugiyama PRKCSH G19P1 VYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMK
P14314 T448 Sugiyama PRKCSH G19P1 CPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKyEQG
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 S55 Sugiyama PKM OIP3 PK2 PK3 PKM2 IDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMNVARLN
P14618 S77 Sugiyama PKM OIP3 PK2 PK3 PKM2 sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs
P14618 T41 Sugiyama PKM OIP3 PK2 PK3 PKM2 AMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtL
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625 S106 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S515 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ
P14625 S64 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14649 T101 Sugiyama MYL6B MLC1SA DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDELKSRR
P15531 T103 Sugiyama NME1 NDPKA NM23 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P15880 T202 Sugiyama RPS2 RPS4 CKVTGRCGsVLVRLIPAPRGtGIVsAPVPKKLLMMAGIDDC
P15880 T285 Sugiyama RPS2 RPS4 PyQEFtDHLVKtHtRVsVQRtQAPAVATt____________
P15924 T61 Sugiyama DSP YYSRRGVITDQNsDGyCQtGtMsRHQNQNTIQELLQNCSDC
P16401 T102 Sugiyama H1-5 H1F5 HIST1H1B RIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEAKPK
P16401 T95 Sugiyama H1-5 H1F5 HIST1H1B DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16401 T99 Sugiyama H1-5 H1F5 HIST1H1B NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P16402 S37 Sugiyama H1-3 H1F3 HIST1H1D KtPVKKKAKKAGATAGKRKAsGPPVsELItKAVAASKERsG
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16402 S59 Sugiyama H1-3 H1F3 HIST1H1D PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P16402 T100 Sugiyama H1-3 H1F3 HIST1H1D RIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAASGEGKPK
P16402 T46 Sugiyama H1-3 H1F3 HIST1H1D KAGATAGKRKAsGPPVsELItKAVAASKERsGVsLAALKKA
P16402 T93 Sugiyama H1-3 H1F3 HIST1H1D DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16402 T97 Sugiyama H1-3 H1F3 HIST1H1D NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAASGEG
P16402 Y72 Sugiyama H1-3 H1F3 HIST1H1D SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P16403 S36 Sugiyama H1-2 H1F2 HIST1H1C EKAPVKKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsG
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S58 Sugiyama H1-2 H1F2 HIST1H1C PPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEKNNS
P16403 T45 Sugiyama H1-2 H1F2 HIST1H1C AKKAGGtPRKAsGPPVsELItKAVAASKERsGVsLAALKKA
P16403 T92 Sugiyama H1-2 H1F2 HIST1H1C DVEKNNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAA
P16403 T96 Sugiyama H1-2 H1F2 HIST1H1C NNSRIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEA
P16403 T99 Sugiyama H1-2 H1F2 HIST1H1C RIKLGLKsLVsKGtLVQtKGtGAsGsFKLNKKAAsGEAKPK
P16403 Y71 Sugiyama H1-2 H1F2 HIST1H1C SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P17066 T49 Sugiyama HSPA6 HSP70B' EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P18124 T17 Sugiyama RPL7 ____MEGVEEKKKEVPAVPEtLKKKRRNFAELKIKRLRKKF
P18621 T151 Sugiyama RPL17 RAHGRINPyMssPCHIEMILtEKEQIVPKPEEEVAQKKKIS
P18621 T79 Sugiyama RPL17 PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE
P18621 Y139 Sugiyama RPL17 VNKAPKMRRRTYRAHGRINPyMssPCHIEMILtEKEQIVPK
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T146 Sugiyama PGAM1 PGAMA CDABP0006 MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P18754 S85 Sugiyama RCC1 CHC1 IPEDVVQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsV
P19105 T159 Sugiyama MYL12A MLCB MRLC3 RLC DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
P19338 S356 Sugiyama NCL LAVVDVRIGMTRKFGyVDFEsAEDLEKALELtGLKVFGNEI
P19338 S532 Sugiyama NCL IKVPQNQNGKSKGyAFIEFAsFEDAKEALNSCNKREIEGRA
P19338 Y351 Sugiyama NCL FAKNDLAVVDVRIGMTRKFGyVDFEsAEDLEKALELtGLKV
P19338 Y525 Sugiyama NCL VFEKATFIKVPQNQNGKSKGyAFIEFAsFEDAKEALNSCNK
P20042 S67 Sugiyama EIF2S2 EIF2B EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK
P20073 S216 Sugiyama ANXA7 ANX7 SNX OK/SW-cl.95 KAMKGFGtDEQAIVDVVANRsNDQRQKIKAAFKTSYGKDLI
P20073 T203 Sugiyama ANXA7 ANX7 SNX OK/SW-cl.95 ANFDAIRDAEILRKAMKGFGtDEQAIVDVVANRsNDQRQKI
P20290 T131 Sugiyama BTF3 NACB OK/SW-cl.8 NQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsIL
P20290 T133 Sugiyama BTF3 NACB OK/SW-cl.8 GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ
P20290 T135 Sugiyama BTF3 NACB OK/SW-cl.8 VIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLG
P20290 T140 Sugiyama BTF3 NACB OK/SW-cl.8 NPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLGADsLt
P21796 S193 SIGNOR|EPSD|PSP VDAC1 VDAC YKTDEFQLHTNVNDGTEFGGsIYQKVNKKLETAVNLAWtAG
P22061 S133 Sugiyama PCMT1 KELVDDsVNNVRKDDPTLLssGRVQLVVGDGRMGYAEEAPY
P22314 T682 Sugiyama UBA1 A1S9T UBE1 NVNQyLtDPKFVERtLRLAGtQPLEVLEAVQRSLVLQRPQT
P22392 T103 Sugiyama NME2 NM23B VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P22492 Y75 Sugiyama H1-6 H1FT H1T HIST1H1T SQERVGMSLVALKKALAAAGyDVEKNNSRIKLSLKSLVNKG
P22626 S212 Sugiyama HNRNPA2B1 HNRPA2B1 EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23396 T242 Sugiyama RPS3 OK/SW-cl.26 PIsEQKGGKPEPPAMPQPVPtA___________________
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23588 S122 Sugiyama EIF4B NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26038 T526 Sugiyama MSN EERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHA
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T107 Sugiyama RPL13 BBC1 OK/SW-cl.46 HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27348 Y48 Sugiyama YWHAQ AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 S78 Sugiyama CALR CRTC GDEEKDKGLQTSQDARFyALsAsFEPFSNKGQTLVVQFTVK
P27797 S80 Sugiyama CALR CRTC EEKDKGLQTSQDARFyALsAsFEPFSNKGQTLVVQFTVKHE
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P28482 T351 Sugiyama MAPK1 ERK2 PRKM1 PRKM2 FDMELDDLPKEKLKELIFEEtARFQPGYRS___________
P29401 S439 Sugiyama TKT VSIGEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVE
P29401 T342 Sugiyama TKT GQALAKLGHAsDRIIALDGDtKNstFsEIFKKEHPDRFIEC
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29692 S60 Sugiyama EEF1D EF1D ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P29692 S64 Sugiyama EEF1D EF1D sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI
P29692 S74 Sugiyama EEF1D EF1D RENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVENQsL
P29692 T73 Sugiyama EEF1D EF1D ARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVENQs
P30041 T192 Sugiyama PRDX6 AOP2 KIAA0106 EKRVAtPVDWKDGDsVMVLPtIPEEEAKKLFPKGVFtKELP
P30041 T48 Sugiyama PRDX6 AOP2 KIAA0106 FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL
P30050 S157 Sugiyama RPL12 QsVGCNVDGRHPHDIIDDINsGAVECPAs____________
P30050 T135 Sugiyama RPL12 QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30050 T18 Sugiyama RPL12 ___MPPKFDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLs
P30050 T25 Sugiyama RPL12 FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD
P30086 S60 Sugiyama PEBP1 PBP PEBP VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK
P30086 T167 Sugiyama PEBP1 PBP PEBP GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30086 Y64 Sugiyama PEBP1 PBP PEBP tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW
P30101 T437 Sugiyama PDIA3 ERP57 ERP60 GRP58 KELGEKLsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsP
P31327 S564 Sugiyama CPS1 TEDRQLFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPV
P31327 S569 Sugiyama CPS1 LFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPVMIRSA
P31327 T326 Sugiyama CPS1 AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP
P31327 T45 Sugiyama CPS1 AHQKWKFSRPGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPS
P31327 T54 Sugiyama CPS1 PGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPSSVAGEVVFN
P31943 S281 Sugiyama HNRNPH1 HNRPH HNRPH1 GRDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAt
P31943 S285 Sugiyama HNRNPH1 HNRPH HNRPH1 NyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDI
P31943 T282 Sugiyama HNRNPH1 HNRPH HNRPH1 RDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtE
P31943 T286 Sugiyama HNRNPH1 HNRPH HNRPH1 yCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIy
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31946 Y50 Sugiyama YWHAB AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31947 Y48 Sugiyama SFN HME1 GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK
P31948 T243 Sugiyama STIP1 KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT
P33176 S950 Sugiyama KIF5B KNS KNS1 PAAsPtHPSAIRGGGAFVQNsQPVAVRGGGGKQV_______
P34931 T39 Sugiyama HSPA1L CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P34931 T49 Sugiyama HSPA1L EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV
P35241 T425 Sugiyama RDX KQAADQMKNQEQLAAELAEFtAKIALLEEAKKKKEEEATEW
P35269 T154 Sugiyama GTF2F1 RAP74 AFEAFPVHNWYNFTPLARHRtLtAEEAEEEWERRNKVLNHF
P35579 S1154 Sugiyama MYH9 KRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNILKK
P35579 S1308 Sugiyama MYH9 LLsQsDSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLs
P35579 S1916 Sugiyama MYH9 LQRELEDAtEtADAMNREVssLKNKLRRGDLPFVVPRRMAR
P35579 S876 Sugiyama MYH9 KVREKQLAAENRLTEMEtLQsQLMAEKLQLQEQLQAETELC
P35579 T1151 Sugiyama MYH9 EKQKRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNI
P35579 T1208 Sugiyama MYH9 QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE
P35579 T1313 Sugiyama MYH9 DSKSSKLTKDFsALEsQLQDtQELLQEENRQKLsLstKLKQ
P35579 T1904 Sugiyama MYH9 EEAQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRG
P35579 T1906 Sugiyama MYH9 AQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRGDL
P35579 T873 Sugiyama MYH9 ELVKVREKQLAAENRLTEMEtLQsQLMAEKLQLQEQLQAET
P35609 T347 Sugiyama ACTN2 RRKHKPPKVQEKCQLEINFNtLQtKLRISNRPAFMPSEGKM
P35609 T350 Sugiyama ACTN2 HKPPKVQEKCQLEINFNtLQtKLRISNRPAFMPSEGKMVSD
P36578 S255 Sugiyama RPL4 RPL1 LNILKLAPGGHVGRFCIWtEsAFRKLDELyGtWRKAAsLKs
P36578 S272 Sugiyama RPL4 RPL1 WtEsAFRKLDELyGtWRKAAsLKsNyNLPMHKMINtDLsRI
P36578 S275 Sugiyama RPL4 RPL1 sAFRKLDELyGtWRKAAsLKsNyNLPMHKMINtDLsRILKs
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T253 Sugiyama RPL4 RPL1 sKLNILKLAPGGHVGRFCIWtEsAFRKLDELyGtWRKAAsL
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578 T69 Sugiyama RPL4 RPL1 RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P36578 Y277 Sugiyama RPL4 RPL1 FRKLDELyGtWRKAAsLKsNyNLPMHKMINtDLsRILKsPE
P37108 T45 Sugiyama SRP14 sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37802 S145 Sugiyama TAGLN2 KIAA0120 CDABP0035 VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN
P37802 S163 Sugiyama TAGLN2 KIAA0120 CDABP0035 LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38117 T172 Sugiyama ETFB FP585 QVTLEGDKLKVEREIDGGLEtLRLKLPAVVTADLRLNEPRy
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 S59 Sugiyama RPS19 LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019 T36 Sugiyama RPS19 RALAAFLKKSGKLKVPEWVDtVKLAKHKELAPyDENWFytR
P39019 T55 Sugiyama RPS19 DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019 T60 Sugiyama RPS19 AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40337 S168 SIGNOR|EPSD|PSP VHL FANITLPVYTLKERCLQVVRsLVKPENyRRLDIVRsLyEDL
P40337 S183 EPSD|PSP VHL LQVVRsLVKPENyRRLDIVRsLyEDLEDHPNVQKDLERLtQ
P40337 T100 EPSD|PSP VHL sPRVVLPVWLNFDGEPQPYPtLPPGtGRRIHsyRGHLWLFR
P40337 T105 EPSD|PSP VHL LPVWLNFDGEPQPYPtLPPGtGRRIHsyRGHLWLFRDAGTH
P40337 T202 EPSD|PSP VHL RsLyEDLEDHPNVQKDLERLtQERIAHQRMGD_________
P40337 Y112 EPSD|PSP VHL DGEPQPYPtLPPGtGRRIHsyRGHLWLFRDAGTHDGLLVNQ
P40337 Y175 EPSD|PSP VHL VYTLKERCLQVVRsLVKPENyRRLDIVRsLyEDLEDHPNVQ
P40429 T153 Sugiyama RPL13A RKFAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQ
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P40855 S147 Sugiyama PEX19 HK33 PXF OK/SW-cl.22 SCLKETLSGLAKNATDLQNssMsEEELTKAMEGLGMDEGDG
P41091 T120 Sugiyama EIF2S3 EIF2G ECyRSCGsstPDEFPtDIPGtKGNFKLVRHVSFVDCPGHDI
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42766 T59 Sugiyama RPL35 GAASKLsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyK
P42766 T64 Sugiyama RPL35 LsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyKPLDLR
P43490 T179 Sugiyama NAMPT PBEF PBEF1 ITVATNSREQKKILAKyLLEtsGNLDGLEyKLHDFGyRGVS
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46776 Y52 Sugiyama RPL27A RGNAGGLHHHRINFDKyHPGyFGKVGMKHYHLKRNQsFCPt
P46779 T81 Sugiyama RPL28 VVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKNK
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P47914 S142 Sugiyama RPL29 KAKAKAKAKDQTKAQAAAPAsVPAQAPKRtQAPtKAsE___
P47914 S26 Sugiyama RPL29 NHTTHNQSRKWHRNGIKKPRsQRYEsLKGVDPKFLRNMRFA
P47914 S31 Sugiyama RPL29 NQSRKWHRNGIKKPRsQRYEsLKGVDPKFLRNMRFAKKHNK
P47914 T155 Sugiyama RPL29 AQAAAPAsVPAQAPKRtQAPtKAsE________________
P47914 Y98 Sugiyama RPL29 PKEVKPKIPKGVSRKLDRLAyIAHPKLGKRARARIAKGLRL
P48163 S336 SIGNOR|PSP ME1 ALEKEGLPKEKAIKKIWLVDsKGLIVKGRASLTQEKEKFAH
P48643 T269 Sugiyama CCT5 CCTE KIAA0098 AILTCPFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMI
P48643 Y274 Sugiyama CCT5 CCTE KIAA0098 PFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQQIKE
P48741 T49 Sugiyama HSPA7 HSP70B EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P49327 T2215 Sugiyama FASN FAS DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN
P49327 T309 Sugiyama FASN FAS yIEAHGtGTKVGDPQELNGItRALCAtRQEPLLIGsTKSNM
P49915 T330 Sugiyama GMPS LPIsDEDRtPRKRISKTLNMttsPEEKRKIIGDTFVKIANE
P50395 T407 Sugiyama GDI2 RABGDIB LVPKDLGtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGs
P50395 T412 Sugiyama GDI2 RABGDIB LGtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFE
P50395 T413 Sugiyama GDI2 RABGDIB GtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFEE
P50897 T261 Sugiyama PPT1 CLN1 PPT SEWFGFYRsGQAKEtIPLQEtsLytQDRLGLKEMDNAGQLV
P51659 T191 Sugiyama HSD17B4 EDH17B4 SDR8C1 LLGLANSLAIEGRKsNIHCNtIAPNAGsRMTQTVMPEDLVE
P51858 T94 Sugiyama HDGF HMG1L2 GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP
P51991 S370 Sugiyama HNRNPA3 HNRPA3 sFGGRssGsPyGGGyGsGGGsGGyGsRRF____________
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P52272 S528 Sugiyama HNRNPM HNRPM NAGR1 IERMGsGVERMGPAIERMGLsMERMVPAGMGAGLERMGPVM
P53634 T431 Sugiyama CTSC CPPI GYGTDSASGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIE
P53999 S10 Sugiyama SUB1 PC4 RPO2TC1 ___________MPKSKELVsssssGsDsDsEVDKKLKRKKQ
P54105 T34 Sugiyama CLNS1A CLCI ICLN EGLLRQQPDTEAVLNGKGLGtGtLyIAEsRLSWLDGsGLGF
P54105 T36 Sugiyama CLNS1A CLCI ICLN LLRQQPDTEAVLNGKGLGtGtLyIAEsRLSWLDGsGLGFSL
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T38 Sugiyama HSPA2 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P54652 T48 Sugiyama HSPA2 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI
P55010 T227 Sugiyama EIF5 ttEEAQRRRMDEISDHAKVLtLsDDLERtIEERVNILFDFV
P55010 T235 Sugiyama EIF5 RMDEISDHAKVLtLsDDLERtIEERVNILFDFVKKKKEEGV
P55036 T264 Sugiyama PSMD4 MCB1 AEAGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEE
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55209 T269 Sugiyama NAP1L1 NRP GPEIMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVT
P55209 T272 Sugiyama NAP1L1 NRP IMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVTKTV
P55209 T64 Sugiyama NAP1L1 NRP QNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNL
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P57053 S39 Sugiyama H2BC12L H2BFS H2BS1 VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P57721 T159 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT sQCGsLIGKGGSKIKEIREstGAQVQVAGDMLPNstERAVT
P57721 T174 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT EIREstGAQVQVAGDMLPNstERAVTISGTPDAIIQCVKQI
P58546 T108 Sugiyama MTPN LSKGADKTVKGPDGLTAFEAtDNQAIKALLQ__________
P58876 S39 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P60174 S106 Sugiyama TPI1 TPI DCGAtWVVLGHsERRHVFGEsDELIGQKVAHALAEGLGVIA
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 S97 Sugiyama TPI1 TPI GEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELIGQKVAHA
P60174 T214 Sugiyama TPI1 TPI KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T90 Sugiyama TPI1 TPI VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 T22 Sugiyama MYL6 CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN
P60660 T44 Sugiyama MYL6 DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDEMNVKV
P60660 T85 Sugiyama MYL6 LDFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVM
P60709 S239 Sugiyama ACTB VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T106 Sugiyama ACTB WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T203 Sugiyama ACTB RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P60709 T303 Sugiyama ACTB MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P60709 T304 Sugiyama ACTB KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P61204 S147 Sugiyama ARF3 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61289 T99 Sugiyama PSME3 LDGPTYKKRRLDECEEAFQGtKVFVMPNGMLKSNQQLVDII
P61313 T80 Sugiyama RPL15 EC45 TCBAP0781 VIyRIRVRRGGRKRPVPKGAtyGKPVHHGVNQLKFARsLQs
P61313 Y81 Sugiyama RPL15 EC45 TCBAP0781 IyRIRVRRGGRKRPVPKGAtyGKPVHHGVNQLKFARsLQsV
P61353 S34 Sugiyama RPL27 LAGRYSGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKVT
P61353 T33 Sugiyama RPL27 VLAGRYSGRKAVIVKNIDDGtsDRPysHALVAGIDRyPRKV
P61586 T60 Sugiyama RHOA ARH12 ARHA RHO12 ENyVADIEVDGKQVELALWDtAGQEDyDRLRPLSYPDTDVI
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61978 Y72 Sugiyama HNRNPK HNRPK KNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISA
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981 Y49 Sugiyama YWHAG NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P62081 S174 Sugiyama RPS7 IKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL
P62081 T172 Sugiyama RPS7 RLIKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEF
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62258 Y49 Sugiyama YWHAE KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62266 T34 Sugiyama RPS23 RSHRRDQKWHDKQYKKAHLGtALKANPFGGAsHAKGIVLEK
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62273 Y34 Sugiyama RPS29 FGQGSRSCRVCSNRHGLIRKyGLNMCRQCFRQYAKDIGFIK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T28 Sugiyama RPS11 RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK
P62316 T40 Sugiyama SNRPD2 SNRPD1 EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62424 T93 Sugiyama RPL7A SURF-3 SURF3 RLKVPPAINQFtQALDRQTAtQLLKLAHKYRPEtKQEKKQR
P62736 S241 Sugiyama ACTA2 ACTSA ACTVS GIG46 VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62745 T60 Sugiyama RHOB ARH6 ARHB ENYVADIEVDGKQVELALWDtAGQEDYDRLRPLSYPDTDVI
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62750 Y144 Sugiyama RPL23A VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________
P62753 S6 Sugiyama RPS6 OK/SW-cl.2 _______________MKLNIsFPAtGCQKLIEVDDERKLRt
P62753 T10 Sugiyama RPS6 OK/SW-cl.2 ___________MKLNIsFPAtGCQKLIEVDDERKLRtFyEK
P62807 S39 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62851 T113 Sugiyama RPS25 sKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA________
P62851 Y109 Sugiyama RPS25 QELLsKGLIKLVSKHRAQVIytRNtKGGDAPAAGEDA____
P62857 T21 Sugiyama RPS28 MDTSRVQPIKLARVTKVLGRtGsQGQCtQVRVEFMDDtsRs
P62857 T38 Sugiyama RPS28 LGRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtL
P62899 T107 Sugiyama RPL31 RLSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN__
P62899 T112 Sugiyama RPL31 RNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN_______
P62899 T113 Sugiyama RPL31 NEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN________
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62899 Y103 Sugiyama RPL31 RIRVRLSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVD
P62899 Y108 Sugiyama RPL31 LSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN___
P62899 Y25 Sugiyama RPL31 KKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRA
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62906 Y11 Sugiyama RPL10A NEDD6 __________MSSKVsRDtLyEAVREVLHGNQRKRRKFLET
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62942 T15 Sugiyama FKBP1A FKBP1 FKBP12 ______MGVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGK
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 S123 Sugiyama RPS27A UBA80 UBCEP1 LKYYKVDENGKIsRLRRECPsDECGAGVFMAsHFDRHyCGK
P62979 S134 Sugiyama RPS27A UBA80 UBCEP1 IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P62979 T147 Sugiyama RPS27A UBA80 UBCEP1 GAGVFMAsHFDRHyCGKCCLtyCFNKPEDK___________
P62979 Y140 Sugiyama RPS27A UBA80 UBCEP1 ECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPEDK____
P62979 Y148 Sugiyama RPS27A UBA80 UBCEP1 AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63104 T194 Sugiyama YWHAZ FSVFYYEILNsPEKACSLAKtAFDEAIAELDtLsEEsyKDs
P63104 T30 Sugiyama YWHAZ AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN
P63104 Y48 Sugiyama YWHAZ sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK
P63167 T26 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63261 S239 Sugiyama ACTG1 ACTG VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T106 Sugiyama ACTG1 ACTG WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T203 Sugiyama ACTG1 ACTG RDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALDF
P63261 T303 Sugiyama ACTG1 ACTG MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P63261 T304 Sugiyama ACTG1 ACTG KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S240 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 T126 Sugiyama YBX1 NSEP1 YB1 GEtVEFDVVEGEKGAEAANVtGPGGVPVQGsKYAADRNHYR
P67809 T271 Sugiyama YBX1 NSEP1 YB1 RQRQPREDGNEEDKENQGDEtQGQQPPQRRyRRNFNYRRRR
P67936 T241 Sugiyama TPM4 EEKLAQAKEENVGLHQtLDQtLNELNCI_____________
P68032 S241 Sugiyama ACTC1 ACTC VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S241 Sugiyama ACTA1 ACTA VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 S48 Sugiyama TUBA1B HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
P68363 T334 Sugiyama TUBA1B ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG
P68363 T41 Sugiyama TUBA1B WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
P68363 T56 Sugiyama TUBA1B MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P68431 Y42 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ATKAARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELL
P78371 T103 Sugiyama CCT2 99D8.1 CCTB VLVDMSRVQDDEVGDGTTsVtVLAAELLREAESLIAKKIHP
P78371 T474 Sugiyama CCT2 99D8.1 CCTB AGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGIT
P78371 T64 Sugiyama CCT2 99D8.1 CCTB GPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVL
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S7 Sugiyama RPL24 ______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731 T52 Sugiyama RPL24 LNAKCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRT
P83731 Y55 Sugiyama RPL24 KCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRTRRA
P83881 S79 Sugiyama RPL36A RPL44 GIG15 MIG6 KAKTTKKIVLRLECVEPNCRsKRMLAIKRCKHFELGGDKKR
P84077 S147 Sugiyama ARF1 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P84098 S12 Sugiyama RPL19 _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098 S122 Sugiyama RPL19 LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI
P84098 S13 Sugiyama RPL19 ________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEIA
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84098 Y124 Sugiyama RPL19 RLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHIHK
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P84243 Y42 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ATKAARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELL
Q01082 S1388 Sugiyama SPTBN1 SPTB2 TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy
Q01105 S161 Sugiyama SET FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q02539 T102 Sugiyama H1-1 H1F1 HIST1H1A RIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKASSVETKPG
Q02539 T95 Sugiyama H1-1 H1F1 HIST1H1A DVEKNNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKAS
Q02539 T99 Sugiyama H1-1 H1F1 HIST1H1A NNSRIKLGIKsLVsKGtLVQtKGtGAsGsFKLNKKASSVET
Q02539 Y74 Sugiyama H1-1 H1F1 HIST1H1A SKERGGVSLAALKKALAAAGyDVEKNNSRIKLGIKsLVsKG
Q02818 S378 Sugiyama NUCB1 NUC EAELNAKAQRLsQETEALGRsQGRLEAQKRELQQAVLHMEQ
Q02878 T213 Sugiyama RPL6 TXREB1 FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q02878 Y216 Sugiyama RPL6 TXREB1 AtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIFDtE
Q04637 T1119 Sugiyama EIF4G1 EIF4F EIF4G EIF4GI GGSGAKPSDAAsEAARPAtstLNRFsALQQAVPtEsTDNRR
Q04760 T35 Sugiyama GLO1 AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q04917 Y49 Sugiyama YWHAH YWHA1 AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q07020 S130 Sugiyama RPL18 RSRILRAGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYR
Q07020 T122 Sugiyama RPL18 ALRVTSRARSRILRAGGKILtFDQLALDsPKGCGtVLLsGP
Q08043 T354 Sugiyama ACTN3 RRLHKPPRIQEKCQLEINFNtLQtKLRLSHRPAFMPSEGKL
Q08043 T357 Sugiyama ACTN3 HKPPRIQEKCQLEINFNtLQtKLRLSHRPAFMPSEGKLVSD
Q12906 T300 Sugiyama ILF3 DRBF MPHOSPH4 NF90 ASGIVMPDGSGIYDPCEKEAtDAIGHLDRQQREDItQsAQH
Q13098 S483 Sugiyama GPS1 COPS1 CSN1 QIHVKsPPREGsQGELtPANsQsRMstNM____________
Q13442 T18 Sugiyama PDAP1 HASPP28 ___MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREEE
Q13442 T92 Sugiyama PDAP1 HASPP28 QKRKGVEGLIDIENPNRVAQttKKVtQLDLDGPKELSRRER
Q13442 T93 Sugiyama PDAP1 HASPP28 KRKGVEGLIDIENPNRVAQttKKVtQLDLDGPKELSRRERE
Q13509 S115 Sugiyama TUBB3 TUBB4 SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13885 S115 Sugiyama TUBB2A TUBB2 sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q14103 S271 Sugiyama HNRNPD AUF1 HNRPD KCEIKVAMSKEQyQQQQQWGsRGGFAGRARGRGGGPSQNWN
Q14103 T91 Sugiyama HNRNPD AUF1 HNRPD sKNEEDEGHsNssPRHsEAAtAQREEWKMFIGGLSWDTTKK
Q14157 S254 Sugiyama UBAP2L KIAA0144 NICE4 TSAWRtAtEEWGtEDWNEDLsEtKIFtAsNVssVPLPAENV
Q14157 T246 Sugiyama UBAP2L KIAA0144 NICE4 GHFEPDDGTSAWRtAtEEWGtEDWNEDLsEtKIFtAsNVss
Q14192 T234 Sugiyama FHL2 DRAL SLIM3 CDLyAKKCAGCTNPISGLGGtKyIsFEERQWHNDCFNCKKC
Q14204 T1307 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 FGRLKDDREKCAKAKEALELtDtGLLsGSEERVQVALEELQ
Q14204 T1309 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 RLKDDREKCAKAKEALELtDtGLLsGSEERVQVALEELQDL
Q14204 T695 Sugiyama DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 NHVEGQKLKQDGDsFRMKLNtQEIFDDWARKVQQRNLGVSG
Q14320 S62 Sugiyama FAM50A DXS9928E HXC26 XAP5 KSNIDKKFsAHyDAVEAELKsstVGLVtLNDMKAKQEALVK
Q14320 T69 Sugiyama FAM50A DXS9928E HXC26 XAP5 FsAHyDAVEAELKsstVGLVtLNDMKAKQEALVKEREKQLA
Q14444 T303 Sugiyama CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 YTEQSEVESTEYVNRQFMAEtQFtsGEKEQVDEWTVETVEV
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14568 T109 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LTIVDTGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
Q14677 T271 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 KDEEETVTTKHIHItQATEttttRHKRTANPsKtIDLGAAA
Q15003 T729 Sugiyama NCAPH BRRN BRRN1 CAPH KIAA0074 PLAFACLLHLANEKNLKLEGtEDLsDVLVRQGD________
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15056 S69 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 LPFNTVQGDIDAIFKDLsIRsVRLVRDKDTDKFKGFCyVEF
Q15056 T100 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 KFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRK
Q15084 S263 Sugiyama PDIA6 ERP5 P5 TXNDC7 FQKGEsPVDyDGGRTRsDIVsRALDLFSDNAPPPELLEIIN
Q15181 T245 Sugiyama PPA1 IOPPP PP DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA
Q15181 T246 Sugiyama PPA1 IOPPP PP HWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDAL
Q15293 T101 Sugiyama RCN1 RCN KERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNVA
Q15293 T144 Sugiyama RCN1 RCN WKDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtF
Q15293 T163 Sugiyama RCN1 RCN AtyGyyLGNPAEFHDssDHHtFKKMLPRDERRFKAADLNGD
Q15293 Y145 Sugiyama RCN1 RCN KDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtFK
Q15365 T127 Sugiyama PCBP1 TQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT
Q15365 T142 Sugiyama PCBP1 EIREstGAQVQVAGDMLPNstERAITIAGVPQSVTECVKQI
Q15366 T127 Sugiyama PCBP2 sQCGsLIGKGGCKIKEIREstGAQVQVAGDMLPNstERAIT
Q15366 T142 Sugiyama PCBP2 EIREstGAQVQVAGDMLPNstERAITIAGIPQSIIECVKQI
Q15369 T41 Sugiyama ELOC TCEB1 LISSDGHEFIVKREHALtsGtIKAMLSGPGQFAENETNEVN
Q15417 T224 Sugiyama CNN3 ISLQMGTNKGAsQAGMLAPGtRRDIYDQKLTLQPVDNSTIS
Q16576 T10 Sugiyama RBBP7 RBAP46 ___________MAsKEMFEDtVEERVINEEYKIWKKNTPFL
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q16695 Y42 Sugiyama H3-4 H3FT HIST3H3 ATKVARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELL
Q16775 T291 Sugiyama HAGH GLO2 HAGH1 PFMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD___
Q16775 T292 Sugiyama HAGH GLO2 HAGH1 FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____
Q27J81 T1039 Sugiyama INF2 C14orf151 C14orf173 PAGDPVGSTRCPASEPGLDAtTASESRGWDLVDAVtPGPQP
Q562R1 S240 Sugiyama ACTBL2 VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE
Q58FF6 T165 Sugiyama HSP90AB4P DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG
Q58FF7 T169 Sugiyama HSP90AB3P HSP90BC DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q58FF8 T104 Sugiyama HSP90AB2P HSP90BB LTLVDTGIGMTKADLINNLGtIAKFQDQTEYLEEMQVKEVV
Q5QJE6 S703 Sugiyama DNTTIP2 ERBP TDIF2 GFPKyFQIGtIVDNPADFyHsRIPKKQRKRTIVEELLADSE
Q5QJE6 T692 Sugiyama DNTTIP2 ERBP TDIF2 PKRFYKKNDRDGFPKyFQIGtIVDNPADFyHsRIPKKQRKR
Q5QNW6 S39 Sugiyama H2BC18 HIST2H2BF VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q5SW79 T870 Sugiyama CEP170 FAM68A KAB KIAA0470 IELIPHINKQTsstPssLALtsAsRIRERsEsLDPDssMDT
Q5T3I0 T271 Sugiyama GPATCH4 GPATC4 KVsDEREGTTKGNEKEDAAGtsGLGELNSREQtNQSLRKGK
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6NXT2 Y41 Sugiyama H3-5 H3F3C LATKAARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELL
Q6PEY2 S48 Sugiyama TUBA3E HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q6PEY2 T334 Sugiyama TUBA3E ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q6PEY2 T41 Sugiyama TUBA3E WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q6PEY2 T56 Sugiyama TUBA3E MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
Q6S8J3 S939 Sugiyama POTEE A26C1A POTE2 VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE
Q6UXH1 T300 Sugiyama CRELD2 UNQ185/PRO211 GYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSYVCVCP
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71DI3 Y42 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ATKAARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELL
Q71U36 S48 Sugiyama TUBA1A TUBA3 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q71U36 T334 Sugiyama TUBA1A TUBA3 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q71U36 T41 Sugiyama TUBA1A TUBA3 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q71U36 T56 Sugiyama TUBA1A TUBA3 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7KZF4 T134 Sugiyama SND1 TDRD11 LGKDTNGENIAEsLVAEGLAtRREGMRANNPEQNRLsECEE
Q7Z2W4 T363 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 NPGstyLASNsTsAPNWKsLtsWtNDQGARRKtVFsPtLPA
Q7Z417 S652 Sugiyama NUFIP2 KIAA1321 PIG1 NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI
Q7Z739 T177 Sugiyama YTHDF3 YPPSSLGRAITDGQAGFGNDtLSKVPGISsIEQGMTGLKIG
Q86V81 S8 Sugiyama ALYREF ALY BEF THOC4 _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG
Q86V81 T148 Sugiyama ALYREF ALY BEF THOC4 EFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQYNG
Q8IX12 S1075 Sugiyama CCAR1 CARP1 DIS LQLLEEKTDEDEKTILNLENsNKsLsGELREVKKDLsQLQE
Q8N129 T46 Sugiyama CNPY4 PSEC0237 UNQ1909/PRO4354 EEDDDTERLPSKCEVCKLLstELQAELsRtGRsREVLELGQ
Q8N129 T55 Sugiyama CNPY4 PSEC0237 UNQ1909/PRO4354 PSKCEVCKLLstELQAELsRtGRsREVLELGQVLDTGKRKR
Q8NBS9 T264 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 KVDCtQHyELCsGNQVRGyPtLLWFRDGKKVDQYKGKRDLE
Q8NBS9 Y262 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 IGKVDCtQHyELCsGNQVRGyPtLLWFRDGKKVDQYKGKRD
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q92598 T795 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 DQDPVVRAQEIKTKIKELNNtCEPVVTQPKPKIEsPKLERt
Q92698 S572 EPSD|PSP RAD54L RAD54A RAKVVERFNSPSSPDFVFMLsSKAGGCGLNLIGANRLVMFD
Q93079 S39 Sugiyama H2BC9 H2BFJ HIST1H2BH VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q969Q0 S79 Sugiyama RPL36AL KAKTTKKIVLRLECVEPNCRsKRMLAIKRCKHFELGGDKKR
Q96CP2 T83 Sugiyama FLYWCH2 HCVMsLGVPGPATLAKALLQtHPEAQRAIEAAPQEPEQKRS
Q96G46 T99 Sugiyama DUS3L DGQtADGQtEEAAEPGEQLQtQKRARGQNKGRPHVKPTNYD
Q96HE7 T148 Sugiyama ERO1A ERO1L UNQ434/PRO865 IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA
Q96PY6 S14 Sugiyama NEK1 KIAA1901 _______MEKYVRLQKIGEGsFGKAILVKstEDGRQYVIKE
Q96PY6 S155 Sugiyama NEK1 KIAA1901 FLTKDGtVQLGDFGIARVLNstVELARTCIGTPYYLSPEIC
Q96PY6 S23 Sugiyama NEK1 KIAA1901 KYVRLQKIGEGsFGKAILVKstEDGRQYVIKEINISRMSSK
Q96PY6 S251 Sugiyama NEK1 KIAA1901 LRSLVSQLFKRNPRDRPSVNsILEKGFIAKRIEKFLSPQLI
Q96PY6 S285 Sugiyama NEK1 KIAA1901 FLSPQLIAEEFCLKTFSKFGsQPIPAKRPAsGQNsISVMPA
Q96PY6 S295 Sugiyama NEK1 KIAA1901 FCLKTFSKFGsQPIPAKRPAsGQNsISVMPAQKITKPAAKy
Q96PY6 S299 Sugiyama NEK1 KIAA1901 TFSKFGsQPIPAKRPAsGQNsISVMPAQKITKPAAKyGIPL
Q96PY6 S414 Sugiyama NEK1 KIAA1901 EKERLERINRAREQGWRNVLsAGGsGEVKAPFLGsGGtIAP
Q96PY6 S418 Sugiyama NEK1 KIAA1901 LERINRAREQGWRNVLsAGGsGEVKAPFLGsGGtIAPSsFS
Q96PY6 S428 Sugiyama NEK1 KIAA1901 GWRNVLsAGGsGEVKAPFLGsGGtIAPSsFSsRGQYEHYHA
Q96PY6 S436 Sugiyama NEK1 KIAA1901 GGsGEVKAPFLGsGGtIAPSsFSsRGQYEHYHAIFDQMQQQ
Q96PY6 S439 Sugiyama NEK1 KIAA1901 GEVKAPFLGsGGtIAPSsFSsRGQYEHYHAIFDQMQQQRAE
Q96PY6 T141 Sugiyama NEK1 KIAA1901 DRKILHRDIKSQNIFLTKDGtVQLGDFGIARVLNstVELAR
Q96PY6 T156 Sugiyama NEK1 KIAA1901 LTKDGtVQLGDFGIARVLNstVELARTCIGTPYYLSPEICE
Q96PY6 T24 Sugiyama NEK1 KIAA1901 YVRLQKIGEGsFGKAILVKstEDGRQYVIKEINISRMSSKE
Q96PY6 T431 Sugiyama NEK1 KIAA1901 NVLsAGGsGEVKAPFLGsGGtIAPSsFSsRGQYEHYHAIFD
Q96PY6 Y315 Sugiyama NEK1 KIAA1901 sGQNsISVMPAQKITKPAAKyGIPLAyKKYGDKKLHEKKPL
Q96PY6 Y321 Sugiyama NEK1 KIAA1901 SVMPAQKITKPAAKyGIPLAyKKYGDKKLHEKKPLQKHKQA
Q99733 T24 Sugiyama NAP1L4 NAP2 HsFsDGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQER
Q99733 T28 Sugiyama NAP1L4 NAP2 DGVPsDsVEAAKNAsNtEKLtDQVMQNPRVLAALQERLDNV
Q99877 S39 Sugiyama H2BC15 H2BFD HIST1H2BN VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99879 S39 Sugiyama H2BC14 H2BFE HIST1H2BM INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99880 S39 Sugiyama H2BC13 H2BFC HIST1H2BL VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q9BQE3 S48 Sugiyama TUBA1C TUBA6 HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV
Q9BQE3 T334 Sugiyama TUBA1C TUBA6 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q9BQE3 T41 Sugiyama TUBA1C TUBA6 WELYCLEHGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKH
Q9BQE3 T56 Sugiyama TUBA1C TUBA6 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BS26 T155 Sugiyama ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 yIRQQKSDPIQEIRDLAEIttLDRSKRNIIGYFEQKDSDNy
Q9BSV6 S93 Sugiyama TSEN34 LENG5 SEN34 RPDSRHHSLALTSFKRQQEEsFQEQSALAAEARETRRQELL
Q9BVA1 S115 Sugiyama TUBB2B sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BWD1 T209 Sugiyama ACAT2 ACTL TENAQKAGHFDKEIVPVLVstRKGLIEVKtDEFPRHGsNIE
Q9BYX7 S239 Sugiyama POTEKP ACTBL3 FKSG30 VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE
Q9C0C2 T1323 Sugiyama TNKS1BP1 KIAA1741 TAB182 ELGVGQMDWGNNLGLRDLEVtCDPDsGGsQGLRGCGVGQMD
Q9H444 S87 Sugiyama CHMP4B C20orf178 SHAX1 QALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEVLK
Q9H444 T85 Sugiyama CHMP4B C20orf178 SHAX1 ALQALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEV
Q9H788 S124 Sugiyama SH2D4A PPP1R38 SH2A LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD
Q9HB71 T209 Sugiyama CACYBP S100A6BP SIP PNAS-107 EGLMNVLKKIyEDGDDDMKRtINKAWVESREKQAKGDTEF_
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NW75 S58 Sugiyama GPATCH2 GPATC2 ESSEQARGGFAEtGDHsRsIsCPLKRQARKRRGRKRRSYNV
Q9NW75 T50 Sugiyama GPATCH2 GPATC2 HDLVsALEESSEQARGGFAEtGDHsRsIsCPLKRQARKRRG
Q9NYF8 T208 Sugiyama BCLAF1 BTF KIAA0164 KDtFEHDPsEsIDEFNKssAtsGDIWPGLsAyDNsPRsPHs
Q9NYF8 T304 Sugiyama BCLAF1 BTF KIAA0164 ysPsQNsPIHHIPsRRsPAKtIAPQNAPRDEsRGRssFyPD
Q9NZZ3 T23 Sugiyama CHMP5 C9orf83 SNF7DC2 CGI-34 HSPC177 PNAS-114 PNAS-2 RLFGKAKPKAPPPsLtDCIGtVDsRAEsIDKKISRLDAELV
Q9P2J5 T728 Sugiyama LARS1 KIAA1352 LARS GHLLLNSEKMSKstGNFLtLtQAIDKFSADGMRLALADAGD
Q9UBR2 T172 Sugiyama CTSZ ETCNNYQAKDQECDKFNQCGtCNEFKECHAIRNYTLWRVGD
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9ULW6 T342 Sugiyama NAP1L2 BPX GTAIEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVT
Q9ULW6 T345 Sugiyama NAP1L2 BPX IEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVTEDF
Q9UMX5 T76 Sugiyama NENF CIR2 SPUF GGEEEDQPIyLAVKGVVFDVtSGKEFYGRGAPYNALTGKDS
Q9UNF1 T117 Sugiyama MAGED2 BCG1 AENKSLAADTKKQNADPQAVtMPATEtKKVSHVADTKVNTK
Q9UNF1 T123 Sugiyama MAGED2 BCG1 AADTKKQNADPQAVtMPATEtKKVSHVADTKVNTKAQETEA
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UNZ2 S212 Sugiyama NSFL1C UBXN2C sLDNGELRSyQDPsNAQFLEsIRRGEVPAELRRLAHGGQVN
Q9UQ35 S1054 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sLCAGVKsstPPGEsyFGVssLQLKGQsQtsPDHRsDtssP
Q9UQ35 T1043 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 DsLVQsCPGsLsLCAGVKsstPPGEsyFGVssLQLKGQsQt
Q9UQ80 T200 Sugiyama PA2G4 EBP1 TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV
Q9UQ80 T60 Sugiyama PA2G4 EBP1 ssGVsVLsLCEKGDAMIMEEtGKIFKKEKEMKKGIAFPTSI
Q9Y247 S62 Sugiyama FAM50B X5L KSQVDKRFSAHyDAVEAELKsstVGLVtLNDMKARQEALVR
Q9Y247 T69 Sugiyama FAM50B X5L FSAHyDAVEAELKsstVGLVtLNDMKARQEALVRERERQLA
Q9Y2B0 S115 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF
Q9Y2B0 S63 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2B0 T100 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL
Q9Y2B0 T132 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF
Q9Y2T7 S137 Sugiyama YBX2 CSDA3 MSY2 EDVFVHQtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEA
Q9Y2T7 T143 Sugiyama YBX2 CSDA3 MSY2 QtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEATNVTGP
Q9Y3F4 T48 Sugiyama STRAP MAWD UNRIP YGYFLISACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLN
Q9Y3F4 T54 Sugiyama STRAP MAWD UNRIP SACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLNKDATKA
Q9Y3U8 Y53 Sugiyama RPL36 LTKHTKFVRDMIREVCGFAPyERRAMELLKVSKDKRALKFI
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Oncogene Induced Senescence R-HSA-2559585 0.000010 4.999 0 0
Nuclear Receptor transcription pathway R-HSA-383280 0.000228 3.642 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 0.000166 3.779 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 0.000238 3.623 0 0
Signal Transduction R-HSA-162582 0.000224 3.650 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 0.000598 3.224 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 0.000598 3.224 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 0.000598 3.224 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 0.000598 3.224 0 0
Signaling by Hippo R-HSA-2028269 0.000295 3.530 0 0
Cellular Senescence R-HSA-2559583 0.000538 3.269 0 0
Protein-protein interactions at synapses R-HSA-6794362 0.001538 2.813 0 0
Sema4D in semaphorin signaling R-HSA-400685 0.001712 2.766 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 0.002512 2.600 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 0.002512 2.600 0 0
Semaphorin interactions R-HSA-373755 0.002544 2.594 0 0
Signaling by ALK R-HSA-201556 0.002795 2.554 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 0.003108 2.508 0 0
Neurexins and neuroligins R-HSA-6794361 0.003204 2.494 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 0.004138 2.383 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 0.004138 2.383 0 0
Signaling by LTK R-HSA-9842663 0.004138 2.383 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 0.004250 2.372 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 0.004611 2.336 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 0.005392 2.268 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 0.005877 2.231 0 0
Signaling by ERBB2 R-HSA-1227986 0.006648 2.177 0 0
Mitophagy R-HSA-5205647 0.006592 2.181 0 0
RAF activation R-HSA-5673000 0.006592 2.181 0 0
Muscle contraction R-HSA-397014 0.006536 2.185 0 0
Apoptotic execution phase R-HSA-75153 0.006569 2.183 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 0.007576 2.121 0 0
Cell-extracellular matrix interactions R-HSA-446353 0.007499 2.125 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 0.007478 2.126 0 0
RAF/MAP kinase cascade R-HSA-5673001 0.007483 2.126 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 0.007499 2.125 0 0
Nervous system development R-HSA-9675108 0.007315 2.136 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 0.008029 2.095 0 0
Axon guidance R-HSA-422475 0.008002 2.097 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 0.009516 2.022 0 0
Regulation of TP53 Expression R-HSA-6804754 0.011427 1.942 0 0
Diseases of cellular response to stress R-HSA-9675132 0.011427 1.942 0 0
Diseases of Cellular Senescence R-HSA-9630747 0.011427 1.942 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 0.011427 1.942 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 0.009906 2.004 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 0.011164 1.952 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 0.010122 1.995 0 0
Interaction between L1 and Ankyrins R-HSA-445095 0.011087 1.955 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 0.010522 1.978 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 0.012468 1.904 0 0
Cell Cycle R-HSA-1640170 0.012196 1.914 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 0.012135 1.916 0 0
Membrane Trafficking R-HSA-199991 0.012968 1.887 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 0.013961 1.855 0 0
Regulation of TP53 Activity R-HSA-5633007 0.013739 1.862 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 0.013501 1.870 0 0
MAPK family signaling cascades R-HSA-5683057 0.014010 1.854 0 0
Amplification of signal from the kinetochores R-HSA-141424 0.014475 1.839 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 0.014475 1.839 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 0.015570 1.808 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 0.015570 1.808 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 0.015570 1.808 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 0.016279 1.788 0 0
Selective autophagy R-HSA-9663891 0.017345 1.761 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 0.017097 1.767 0 0
L1CAM interactions R-HSA-373760 0.016906 1.772 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 0.017395 1.760 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 0.018692 1.728 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 0.019593 1.708 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 0.019593 1.708 0 0
Regulation of PTEN gene transcription R-HSA-8943724 0.020717 1.684 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 0.024406 1.613 0 0
Signaling by GSK3beta mutants R-HSA-5339716 0.022856 1.641 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 0.023923 1.621 0 0
Striated Muscle Contraction R-HSA-390522 0.023230 1.634 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 0.023923 1.621 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 0.022582 1.646 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 0.022582 1.646 0 0
Intracellular signaling by second messengers R-HSA-9006925 0.021338 1.671 0 0
EPH-Ephrin signaling R-HSA-2682334 0.023016 1.638 0 0
MHC class II antigen presentation R-HSA-2132295 0.023650 1.626 0 0
Cell Cycle, Mitotic R-HSA-69278 0.021107 1.676 0 0
Mitochondrial calcium ion transport R-HSA-8949215 0.023923 1.621 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 0.026951 1.569 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 0.026951 1.569 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 0.026951 1.569 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 0.026951 1.569 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 0.026951 1.569 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 0.026951 1.569 0 0
Notch-HLH transcription pathway R-HSA-350054 0.026839 1.571 0 0
Signal amplification R-HSA-392518 0.025465 1.594 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 0.025396 1.595 0 0
Mitotic Prometaphase R-HSA-68877 0.025446 1.594 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 0.029903 1.524 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 0.032369 1.490 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 0.029903 1.524 0 0
PIP3 activates AKT signaling R-HSA-1257604 0.030477 1.516 0 0
Regulation of TP53 Degradation R-HSA-6804757 0.030337 1.518 0 0
Potassium Channels R-HSA-1296071 0.029903 1.524 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 0.031436 1.503 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 0.032369 1.490 0 0
NrCAM interactions R-HSA-447038 0.032369 1.490 0 0
HSF1-dependent transactivation R-HSA-3371571 0.032594 1.487 0 0
Voltage gated Potassium channels R-HSA-1296072 0.032978 1.482 0 0
Thromboxane signalling through TP receptor R-HSA-428930 0.033282 1.478 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 0.034679 1.460 0 0
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects R-HSA-9646304 0.039085 1.408 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 0.039085 1.408 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 0.039085 1.408 0 0
Evasion of Oncogene Induced Senescence Due to p14ARF Defects R-HSA-9646303 0.039085 1.408 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 0.036776 1.434 0 0
Long-term potentiation R-HSA-9620244 0.036813 1.434 0 0
Adipogenesis R-HSA-9843745 0.036419 1.439 0 0
Mitotic Spindle Checkpoint R-HSA-69618 0.036361 1.439 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 0.036689 1.435 0 0
Cardiac conduction R-HSA-5576891 0.036419 1.439 0 0
XBP1(S) activates chaperone genes R-HSA-381038 0.038999 1.409 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 0.041200 1.385 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 0.041200 1.385 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 0.041200 1.385 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 0.041409 1.383 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 0.041409 1.383 0 0
Phase 4 - resting membrane potential R-HSA-5576886 0.046938 1.328 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 0.044498 1.352 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 0.048291 1.316 0 0
Intra-Golgi traffic R-HSA-6811438 0.048291 1.316 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 0.047166 1.326 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 0.044498 1.352 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 0.045213 1.345 0 0
Signaling by Interleukins R-HSA-449147 0.044169 1.355 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 0.048651 1.313 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 0.049145 1.309 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 0.049801 1.303 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 0.050818 1.294 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 0.051781 1.286 0 0
IRE1alpha activates chaperones R-HSA-381070 0.052172 1.283 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 0.053011 1.276 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 0.076645 1.116 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9632697 0.076645 1.116 0 0
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function R-HSA-9645722 0.076645 1.116 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 R-HSA-9630791 0.076645 1.116 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 0.112739 0.948 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 0.112739 0.948 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 0.112739 0.948 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 0.112739 0.948 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 0.112739 0.948 0 0
Defective SLC12A3 causes Gitelman syndrome (GS) R-HSA-5619087 0.112739 0.948 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 0.112739 0.948 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 0.112739 0.948 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 0.061149 1.214 0 0
Defective GCLC causes HAGGSD R-HSA-5578999 0.180755 0.743 0 0
Classical Kir channels R-HSA-1296053 0.180755 0.743 0 0
FGFR1b ligand binding and activation R-HSA-190370 0.072123 1.142 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 0.072123 1.142 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 0.072123 1.142 0 0
WNT mediated activation of DVL R-HSA-201688 0.083674 1.077 0 0
HCN channels R-HSA-1296061 0.212786 0.672 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 0.212786 0.672 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 0.212786 0.672 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 0.095740 1.019 0 0
Folding of actin by CCT/TriC R-HSA-390450 0.095740 1.019 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 0.095740 1.019 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 0.108263 0.966 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 0.108263 0.966 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 0.108263 0.966 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 0.108263 0.966 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 0.108263 0.966 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 0.243565 0.613 0 0
IRS activation R-HSA-74713 0.243565 0.613 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 0.243565 0.613 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 0.059017 1.229 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 0.059017 1.229 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 0.121190 0.917 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 0.121190 0.917 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 0.273143 0.564 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 0.273143 0.564 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 0.079554 1.099 0 0
Adenylate cyclase activating pathway R-HSA-170660 0.148054 0.830 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 0.087002 1.060 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 0.087002 1.060 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 0.087002 1.060 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 0.087002 1.060 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 0.094733 1.023 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 0.094733 1.023 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 0.094733 1.023 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 0.161901 0.791 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 0.301567 0.521 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 0.301567 0.521 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 0.102734 0.988 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 0.175967 0.755 0 0
SHC1 events in EGFR signaling R-HSA-180336 0.175967 0.755 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 0.175967 0.755 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 0.110992 0.955 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 0.077849 1.109 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 0.119495 0.923 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 0.119495 0.923 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 0.328880 0.483 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 0.328880 0.483 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 0.328880 0.483 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 0.328880 0.483 0 0
IFNG signaling activates MAPKs R-HSA-9732724 0.328880 0.483 0 0
SOS-mediated signalling R-HSA-112412 0.328880 0.483 0 0
FGFR3b ligand binding and activation R-HSA-190371 0.328880 0.483 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 0.204612 0.689 0 0
Signaling by EGFR in Cancer R-HSA-1643713 0.137185 0.863 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 0.146345 0.835 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 0.146345 0.835 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 0.219120 0.659 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 0.355127 0.450 0 0
Type I hemidesmosome assembly R-HSA-446107 0.355127 0.450 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 0.355127 0.450 0 0
phospho-PLA2 pathway R-HSA-111995 0.355127 0.450 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 0.355127 0.450 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 0.233712 0.631 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 0.248357 0.605 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 0.380349 0.420 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 0.078526 1.105 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 0.184786 0.733 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 0.263029 0.580 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 0.263029 0.580 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 0.263029 0.580 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 0.263029 0.580 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 0.171190 0.767 0 0
Signaling downstream of RAS mutants R-HSA-9649948 0.171190 0.767 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 0.171190 0.767 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 0.150482 0.823 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 0.427876 0.369 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 0.427876 0.369 0 0
Regulation of RAS by GAPs R-HSA-5658442 0.202918 0.693 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 0.350396 0.455 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 0.193961 0.712 0 0
Signaling by RAF1 mutants R-HSA-9656223 0.310734 0.508 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 0.406724 0.391 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 0.314805 0.502 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 0.314805 0.502 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 0.364698 0.438 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 0.332655 0.478 0 0
AURKA Activation by TPX2 R-HSA-8854518 0.341599 0.466 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 0.404133 0.393 0 0
Centrosome maturation R-HSA-380287 0.421841 0.375 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 0.353541 0.452 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 0.235941 0.627 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 0.165231 0.782 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 0.174931 0.757 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 0.235941 0.627 0 0
Chaperonin-mediated protein folding R-HSA-390466 0.092855 1.032 0 0
DAP12 signaling R-HSA-2424491 0.057576 1.240 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 0.089118 1.050 0 0
COPI-mediated anterograde transport R-HSA-6807878 0.257282 0.590 0 0
Oncogenic MAPK signaling R-HSA-6802957 0.170484 0.768 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 0.083407 1.079 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 0.359503 0.444 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 0.108263 0.966 0 0
Neutrophil degranulation R-HSA-6798695 0.356524 0.448 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 0.360771 0.443 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 0.260874 0.584 0 0
Activation of GABAB receptors R-HSA-991365 0.321539 0.493 0 0
Signal attenuation R-HSA-74749 0.095740 1.019 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 0.328880 0.483 0 0
Protein folding R-HSA-391251 0.117063 0.932 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 0.307637 0.512 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 0.075730 1.121 0 0
Signaling by FGFR R-HSA-190236 0.270580 0.568 0 0
Germ layer formation at gastrulation R-HSA-9754189 0.072400 1.140 0 0
Regulation of CDH11 function R-HSA-9762292 0.095740 1.019 0 0
Co-inhibition by CTLA4 R-HSA-389513 0.263029 0.580 0 0
PI3K/AKT activation R-HSA-198203 0.404586 0.393 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 0.292361 0.534 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 0.378828 0.422 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 0.132426 0.878 0 0
Chaperone Mediated Autophagy R-HSA-9613829 0.065550 1.183 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 0.306976 0.513 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 0.257060 0.590 0 0
Activation of the pre-replicative complex R-HSA-68962 0.174931 0.757 0 0
Signaling by RAS mutants R-HSA-6802949 0.171190 0.767 0 0
GABA B receptor activation R-HSA-977444 0.321539 0.493 0 0
DNA Double Strand Break Response R-HSA-5693606 0.182685 0.738 0 0
DNA Double-Strand Break Repair R-HSA-5693532 0.246639 0.608 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 0.072123 1.142 0 0
IRAK1 recruits IKK complex R-HSA-937039 0.134469 0.871 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 0.134469 0.871 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 0.134469 0.871 0 0
Formation of axial mesoderm R-HSA-9796292 0.148054 0.830 0 0
cGMP effects R-HSA-418457 0.161901 0.791 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 0.204612 0.689 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 0.380349 0.420 0 0
TGFBR3 expression R-HSA-9839394 0.350396 0.455 0 0
Separation of Sister Chromatids R-HSA-2467813 0.116458 0.934 0 0
COPII-mediated vesicle transport R-HSA-204005 0.377396 0.423 0 0
Signaling by FGFR2 R-HSA-5654738 0.275889 0.559 0 0
Aggrephagy R-HSA-9646399 0.289165 0.539 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 0.080217 1.096 0 0
Signaling by FGFR3 R-HSA-5654741 0.163547 0.786 0 0
ER to Golgi Anterograde Transport R-HSA-199977 0.128330 0.892 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 0.099539 1.002 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 0.109999 0.959 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 0.336011 0.474 0 0
Myogenesis R-HSA-525793 0.364673 0.438 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 0.310755 0.508 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 0.055332 1.257 0 0
Signaling by FGFR4 R-HSA-5654743 0.148651 0.828 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 0.225716 0.646 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 0.302463 0.519 0 0
TNFR1-mediated ceramide production R-HSA-5626978 0.212786 0.672 0 0
Formation of the posterior neural plate R-HSA-9832991 0.108263 0.966 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 0.243565 0.613 0 0
FGFR1c ligand binding and activation R-HSA-190373 0.148054 0.830 0 0
PTK6 Expression R-HSA-8849473 0.328880 0.483 0 0
mRNA Editing: C to U Conversion R-HSA-72200 0.328880 0.483 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 0.355127 0.450 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 0.233712 0.631 0 0
Signaling by FGFR1 R-HSA-5654736 0.115421 0.938 0 0
FGFR2b ligand binding and activation R-HSA-190377 0.427876 0.369 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 0.392848 0.406 0 0
IGF1R signaling cascade R-HSA-2428924 0.163063 0.788 0 0
Parasite infection R-HSA-9664407 0.179707 0.745 0 0
Leishmania phagocytosis R-HSA-9664417 0.179707 0.745 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 0.179707 0.745 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 0.148054 0.830 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 0.246465 0.608 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 0.321532 0.493 0 0
PTEN Regulation R-HSA-6807070 0.098825 1.005 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 0.138332 0.859 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 0.138332 0.859 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 0.138332 0.859 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 0.138332 0.859 0 0
TCF dependent signaling in response to WNT R-HSA-201681 0.188211 0.725 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 0.212786 0.672 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 0.212786 0.672 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 0.243565 0.613 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 0.273143 0.564 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 0.175967 0.755 0 0
Signalling to RAS R-HSA-167044 0.277705 0.556 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 0.169507 0.771 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 0.217155 0.663 0 0
FGFR1 ligand binding and activation R-HSA-190242 0.233712 0.631 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 0.215151 0.667 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 0.420444 0.376 0 0
mRNA Editing R-HSA-75072 0.083674 1.077 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 0.204612 0.689 0 0
Specification of the neural plate border R-HSA-9834899 0.248357 0.605 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 0.364673 0.438 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 0.406724 0.391 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 0.072484 1.140 0 0
Autophagy R-HSA-9612973 0.092966 1.032 0 0
Formation of editosomes by ADAR proteins R-HSA-77042 0.076645 1.116 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 0.112739 0.948 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 0.112739 0.948 0 0
mRNA Editing: A to I Conversion R-HSA-75064 0.147424 0.831 0 0
C6 deamination of adenosine R-HSA-75102 0.147424 0.831 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 0.083674 1.077 0 0
Ionotropic activity of kainate receptors R-HSA-451306 0.108263 0.966 0 0
vRNP Assembly R-HSA-192905 0.108263 0.966 0 0
Signaling by APC mutants R-HSA-4839744 0.108263 0.966 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 0.243565 0.613 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 0.121190 0.917 0 0
Signaling by AXIN mutants R-HSA-4839735 0.121190 0.917 0 0
Signaling by AMER1 mutants R-HSA-4839748 0.121190 0.917 0 0
Synaptic adhesion-like molecules R-HSA-8849932 0.065550 1.183 0 0
Formation of the Editosome R-HSA-75094 0.273143 0.564 0 0
Intracellular metabolism of fatty acids regulates insulin secretion R-HSA-434313 0.301567 0.521 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 0.328880 0.483 0 0
PKA activation in glucagon signalling R-HSA-164378 0.233712 0.631 0 0
Cargo concentration in the ER R-HSA-5694530 0.184786 0.733 0 0
Signaling by WNT in cancer R-HSA-4791275 0.194782 0.710 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 0.404586 0.393 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 0.404586 0.393 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 0.404586 0.393 0 0
DNA replication initiation R-HSA-68952 0.404586 0.393 0 0
Ion influx/efflux at host-pathogen interface R-HSA-6803544 0.404586 0.393 0 0
Developmental Cell Lineages R-HSA-9734767 0.106525 0.973 0 0
DAP12 interactions R-HSA-2172127 0.156032 0.807 0 0
Signalling to ERKs R-HSA-187687 0.235941 0.627 0 0
G alpha (12/13) signalling events R-HSA-416482 0.132566 0.878 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 0.387520 0.412 0 0
G-protein mediated events R-HSA-112040 0.182685 0.738 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 0.336011 0.474 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 0.297646 0.526 0 0
MTOR signalling R-HSA-165159 0.321539 0.493 0 0
Macroautophagy R-HSA-1632852 0.105003 0.979 0 0
Signaling by WNT R-HSA-195721 0.291144 0.536 0 0
Opioid Signalling R-HSA-111885 0.311373 0.507 0 0
Receptor Mediated Mitophagy R-HSA-8934903 0.095740 1.019 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 0.243565 0.613 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 0.355127 0.450 0 0
Kinesins R-HSA-983189 0.057231 1.242 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 0.289165 0.539 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 0.289165 0.539 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 0.406724 0.391 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 0.306405 0.514 0 0
Signaling by NOTCH1 R-HSA-1980143 0.053792 1.269 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 0.138332 0.859 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 0.106047 0.975 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 0.212786 0.672 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 0.328880 0.483 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 0.328880 0.483 0 0
GPER1 signaling R-HSA-9634597 0.075730 1.121 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 0.380349 0.420 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 0.380349 0.420 0 0
Attenuation phase R-HSA-3371568 0.289165 0.539 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 0.378828 0.422 0 0
Signaling by TGFBR3 R-HSA-9839373 0.364698 0.438 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 0.292361 0.534 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 0.323302 0.490 0 0
Pyroptosis R-HSA-5620971 0.155698 0.808 0 0
mTORC1-mediated signalling R-HSA-166208 0.306976 0.513 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 0.156721 0.805 0 0
Meiosis R-HSA-1500620 0.170484 0.768 0 0
Acyl chain remodelling of PS R-HSA-1482801 0.350396 0.455 0 0
G2/M Checkpoints R-HSA-69481 0.339233 0.470 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 0.063893 1.195 0 0
Vesicle-mediated transport R-HSA-5653656 0.094603 1.024 0 0
Signaling by PTK6 R-HSA-8848021 0.067388 1.171 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 0.067388 1.171 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 0.204908 0.688 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 0.392848 0.406 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 0.406724 0.391 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 0.087002 1.060 0 0
Negative regulation of MAPK pathway R-HSA-5675221 0.134312 0.872 0 0
Generic Transcription Pathway R-HSA-212436 0.150461 0.823 0 0
Cell Cycle Checkpoints R-HSA-69620 0.057418 1.241 0 0
Leishmania infection R-HSA-9658195 0.424074 0.373 0 0
Parasitic Infection Pathways R-HSA-9824443 0.424074 0.373 0 0
Mitotic Anaphase R-HSA-68882 0.094758 1.023 0 0
Breakdown of the nuclear lamina R-HSA-352238 0.112739 0.948 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 0.180755 0.743 0 0
Sensory perception of sour taste R-HSA-9729555 0.212786 0.672 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 0.243565 0.613 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 0.273143 0.564 0 0
Activation of SMO R-HSA-5635838 0.190216 0.721 0 0
Ca2+ activated K+ channels R-HSA-1296052 0.328880 0.483 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 0.328880 0.483 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 0.233712 0.631 0 0
ARMS-mediated activation R-HSA-170984 0.380349 0.420 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 0.427876 0.369 0 0
Synthesis of PI R-HSA-1483226 0.427876 0.369 0 0
Meiotic synapsis R-HSA-1221632 0.227758 0.643 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 0.176239 0.754 0 0
Ca2+ pathway R-HSA-4086398 0.224282 0.649 0 0
G2/M DNA damage checkpoint R-HSA-69473 0.231477 0.635 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 0.097140 1.013 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 0.392848 0.406 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 0.353934 0.451 0 0
RNA Polymerase II Transcription R-HSA-73857 0.339462 0.469 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 0.072600 1.139 0 0
Metabolism of cofactors R-HSA-8978934 0.386326 0.413 0 0
Cellular responses to stress R-HSA-2262752 0.205068 0.688 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 0.094733 1.023 0 0
PLC beta mediated events R-HSA-112043 0.144352 0.841 0 0
Biotin transport and metabolism R-HSA-196780 0.175967 0.755 0 0
Neuronal System R-HSA-112316 0.058965 1.229 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 0.278421 0.555 0 0
M Phase R-HSA-68886 0.132767 0.877 0 0
Degradation of CDH1 R-HSA-9766229 0.396783 0.401 0 0
G2/M Transition R-HSA-69275 0.123423 0.909 0 0
Ion transport by P-type ATPases R-HSA-936837 0.323722 0.490 0 0
Cellular responses to stimuli R-HSA-8953897 0.178855 0.747 0 0
Signaling by VEGF R-HSA-194138 0.057305 1.242 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 0.142958 0.845 0 0
Mitotic G2-G2/M phases R-HSA-453274 0.129622 0.887 0 0
Histamine receptors R-HSA-390650 0.180755 0.743 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 0.094733 1.023 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 0.301567 0.521 0 0
Rap1 signalling R-HSA-392517 0.248357 0.605 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 0.380349 0.420 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 0.204908 0.688 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 0.111035 0.955 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 0.137185 0.863 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 0.059017 1.229 0 0
Formation of the anterior neural plate R-HSA-9823739 0.175967 0.755 0 0
Integration of energy metabolism R-HSA-163685 0.162274 0.790 0 0
Ca-dependent events R-HSA-111996 0.141409 0.850 0 0
Rab regulation of trafficking R-HSA-9007101 0.156824 0.805 0 0
Post NMDA receptor activation events R-HSA-438064 0.187979 0.726 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 0.370216 0.432 0 0
MECP2 regulates transcription factors R-HSA-9022707 0.061149 1.214 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 0.212786 0.672 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 0.095740 1.019 0 0
RUNX2 regulates chondrocyte maturation R-HSA-8941284 0.243565 0.613 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 0.243565 0.613 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 0.273143 0.564 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 0.148054 0.830 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 0.094733 1.023 0 0
NADPH regeneration R-HSA-389542 0.301567 0.521 0 0
Trafficking of AMPA receptors R-HSA-399719 0.062345 1.205 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 0.328880 0.483 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 0.328880 0.483 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 0.328880 0.483 0 0
PKA activation R-HSA-163615 0.233712 0.631 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 0.380349 0.420 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 0.380349 0.420 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 0.427876 0.369 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 0.278421 0.555 0 0
MAP kinase activation R-HSA-450294 0.297044 0.527 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 0.420444 0.376 0 0
Regulated Necrosis R-HSA-5218859 0.189412 0.723 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 0.073742 1.132 0 0
Ion channel transport R-HSA-983712 0.212999 0.672 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 0.073742 1.132 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 0.073742 1.132 0 0
Ion homeostasis R-HSA-5578775 0.253310 0.596 0 0
Synthesis of PA R-HSA-1483166 0.261958 0.582 0 0
Response of endothelial cells to shear stress R-HSA-9860931 0.179304 0.746 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 0.375432 0.425 0 0
Sensory processing of sound R-HSA-9659379 0.062374 1.205 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 0.404586 0.393 0 0
Pexophagy R-HSA-9664873 0.404586 0.393 0 0
Interleukin-17 signaling R-HSA-448424 0.377396 0.423 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 0.114858 0.940 0 0
Toll-like Receptor Cascades R-HSA-168898 0.139238 0.856 0 0
Pyruvate metabolism R-HSA-70268 0.337377 0.472 1 0
Platelet homeostasis R-HSA-418346 0.332148 0.479 0 0
Platelet sensitization by LDL R-HSA-432142 0.065550 1.183 0 0
Maturation of nucleoprotein R-HSA-9683610 0.148054 0.830 0 0
GP1b-IX-V activation signalling R-HSA-430116 0.380349 0.420 0 0
Interleukin-1 signaling R-HSA-9020702 0.290827 0.536 0 0
Stimuli-sensing channels R-HSA-2672351 0.206356 0.685 0 0
Diseases of programmed cell death R-HSA-9645723 0.193961 0.712 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 0.386326 0.413 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 0.289165 0.539 0 0
Diseases of Immune System R-HSA-5260271 0.289165 0.539 0 0
Mitochondrial protein import R-HSA-1268020 0.305911 0.514 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 0.062374 1.205 0 0
Interleukin-2 signaling R-HSA-9020558 0.108263 0.966 0 0
STING mediated induction of host immune responses R-HSA-1834941 0.072400 1.140 0 0
Formation of the nephric duct R-HSA-9830364 0.128230 0.892 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 0.275889 0.559 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 0.200825 0.697 0 0
Diseases of DNA repair R-HSA-9675135 0.364698 0.438 0 0
ESR-mediated signaling R-HSA-8939211 0.330828 0.480 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 0.061149 1.214 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 0.083674 1.077 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 0.273143 0.564 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 0.273143 0.564 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 0.087002 1.060 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 0.175967 0.755 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 0.110992 0.955 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 0.328880 0.483 0 0
Synthesis of PG R-HSA-1483148 0.204612 0.689 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 0.380349 0.420 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 0.094886 1.023 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 0.204908 0.688 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 0.306976 0.513 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 0.427876 0.369 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 0.427876 0.369 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 0.130842 0.883 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 0.404133 0.393 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 0.143541 0.843 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 0.360088 0.444 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 0.240682 0.619 0 0
Signaling by NTRKs R-HSA-166520 0.344297 0.463 0 0
MyD88-independent TLR4 cascade R-HSA-166166 0.360088 0.444 0 0
PI Metabolism R-HSA-1483255 0.086283 1.064 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 0.325201 0.488 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 0.215151 0.667 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 0.350396 0.455 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 0.406724 0.391 0 0
Signaling by ALK in cancer R-HSA-9700206 0.200825 0.697 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 0.094733 1.023 0 0
Ephrin signaling R-HSA-3928664 0.233712 0.631 0 0
Signal transduction by L1 R-HSA-445144 0.263029 0.580 0 0
Neurodegenerative Diseases R-HSA-8863678 0.336011 0.474 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 0.336011 0.474 0 0
Deubiquitination R-HSA-5688426 0.416371 0.381 0 0
FOXO-mediated transcription R-HSA-9614085 0.076767 1.115 0 0
Calmodulin induced events R-HSA-111933 0.246465 0.608 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 0.273143 0.564 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 0.190216 0.721 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 0.380349 0.420 0 0
Creatine metabolism R-HSA-71288 0.263029 0.580 0 0
Tandem pore domain potassium channels R-HSA-1296346 0.404586 0.393 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 0.156721 0.805 0 0
CaM pathway R-HSA-111997 0.246465 0.608 0 0
Estrogen-dependent gene expression R-HSA-9018519 0.269275 0.570 0 0
Phospholipid metabolism R-HSA-1483257 0.279274 0.554 0 0
Co-stimulation by CD28 R-HSA-389356 0.186835 0.729 0 0
ChREBP activates metabolic gene expression R-HSA-163765 0.108263 0.966 0 0
Interleukin-1 family signaling R-HSA-446652 0.146569 0.834 0 0
PKR-mediated signaling R-HSA-9833482 0.275889 0.559 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 0.328182 0.484 0 0
Programmed Cell Death R-HSA-5357801 0.070961 1.149 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 0.273143 0.564 0 0
Malate-aspartate shuttle R-HSA-9856872 0.161901 0.791 0 0
TRP channels R-HSA-3295583 0.137185 0.863 0 0
Maturation of nucleoprotein R-HSA-9694631 0.248357 0.605 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 0.277705 0.556 0 0
Suppression of apoptosis R-HSA-9635465 0.427876 0.369 0 0
NRAGE signals death through JNK R-HSA-193648 0.253310 0.596 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 0.364673 0.438 0 0
DAG and IP3 signaling R-HSA-1489509 0.353934 0.451 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 0.276671 0.558 0 0
Syndecan interactions R-HSA-3000170 0.321532 0.493 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 0.380349 0.420 0 0
MITF-M-dependent gene expression R-HSA-9856651 0.139119 0.857 0 0
EPHB-mediated forward signaling R-HSA-3928662 0.343147 0.465 0 0
Apoptosis R-HSA-109581 0.110294 0.957 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 0.110992 0.955 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 0.072484 1.140 0 0
Prostanoid ligand receptors R-HSA-391908 0.427876 0.369 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 0.427876 0.369 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 0.378828 0.422 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 0.219391 0.659 0 0
Cytokine Signaling in Immune system R-HSA-1280215 0.378389 0.422 0 0
Apoptotic factor-mediated response R-HSA-111471 0.233712 0.631 0 0
Signaling by Leptin R-HSA-2586552 0.404586 0.393 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 0.378828 0.422 0 0
TNF signaling R-HSA-75893 0.253310 0.596 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 0.355127 0.450 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 0.380349 0.420 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 0.233712 0.631 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 0.204908 0.688 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 0.225499 0.647 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 0.364673 0.438 0 0
Interleukin-37 signaling R-HSA-9008059 0.057576 1.240 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 0.404133 0.393 0 0
Death Receptor Signaling R-HSA-73887 0.379926 0.420 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 0.332655 0.478 0 0
Regulation of TNFR1 signaling R-HSA-5357905 0.364698 0.438 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 0.278421 0.555 0 0
Unfolded Protein Response (UPR) R-HSA-381119 0.286204 0.543 0 0
Interleukin-12 signaling R-HSA-9020591 0.430649 0.366 0 0
Aspartate and asparagine metabolism R-HSA-8963693 0.434001 0.363 0 0
Smooth Muscle Contraction R-HSA-445355 0.438834 0.358 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 0.442913 0.354 0 0
Immune System R-HSA-168256 0.447967 0.349 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 0.450257 0.347 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 0.450257 0.347 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 0.450257 0.347 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 0.450257 0.347 0 0
ERKs are inactivated R-HSA-202670 0.450257 0.347 0 0
Activation of RAC1 R-HSA-428540 0.450257 0.347 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 0.450257 0.347 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 0.450257 0.347 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 0.450257 0.347 0 0
Cellular response to heat stress R-HSA-3371556 0.451072 0.346 0 0
Hedgehog 'off' state R-HSA-5610787 0.453959 0.343 0 0
Signaling by NOTCH3 R-HSA-9012852 0.459443 0.338 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 0.460588 0.337 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 0.460588 0.337 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 0.460588 0.337 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 0.460588 0.337 0 0
FGFR1 mutant receptor activation R-HSA-1839124 0.460588 0.337 0 0
Integrin signaling R-HSA-354192 0.460588 0.337 0 0
Regulation of necroptotic cell death R-HSA-5675482 0.460588 0.337 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 0.460588 0.337 0 0
Clathrin-mediated endocytosis R-HSA-8856828 0.460984 0.336 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 0.461598 0.336 0 0
Signaling by EGFR R-HSA-177929 0.469625 0.328 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 0.469625 0.328 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 0.469625 0.328 0 0
Scavenging by Class F Receptors R-HSA-3000484 0.471763 0.326 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 0.471763 0.326 0 0
GRB2 events in EGFR signaling R-HSA-179812 0.471763 0.326 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 0.471763 0.326 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 0.471763 0.326 0 0
MET activates RAS signaling R-HSA-8851805 0.471763 0.326 0 0
Interleukin-15 signaling R-HSA-8983432 0.471763 0.326 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 0.471763 0.326 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 0.471763 0.326 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 0.471763 0.326 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 0.471763 0.326 0 0
Formation of the cornified envelope R-HSA-6809371 0.471765 0.326 0 0
Resolution of D-Loop Structures R-HSA-5693537 0.473606 0.325 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 0.473606 0.325 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 0.473606 0.325 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 0.473606 0.325 0 0
Processing of DNA double-strand break ends R-HSA-5693607 0.474075 0.324 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 0.479721 0.319 0 0
Regulation of CDH1 Function R-HSA-9764561 0.479721 0.319 0 0
Nuclear Envelope Breakdown R-HSA-2980766 0.479721 0.319 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 0.480961 0.318 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 0.485440 0.314 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 0.485440 0.314 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 0.485440 0.314 0 0
Gene expression (Transcription) R-HSA-74160 0.486245 0.313 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 0.486432 0.313 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 0.486432 0.313 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 0.486432 0.313 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 0.486432 0.313 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 0.486432 0.313 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 0.489725 0.310 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 0.492430 0.308 0 0
FGFR2c ligand binding and activation R-HSA-190375 0.492430 0.308 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 0.492430 0.308 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 0.492430 0.308 0 0
FGFR4 ligand binding and activation R-HSA-190322 0.492430 0.308 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 0.492430 0.308 0 0
Frs2-mediated activation R-HSA-170968 0.492430 0.308 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 0.492430 0.308 0 0
FGFR3 mutant receptor activation R-HSA-2033514 0.492430 0.308 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 0.492430 0.308 0 0
Ub-specific processing proteases R-HSA-5689880 0.498467 0.302 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 0.499061 0.302 0 0
Potential therapeutics for SARS R-HSA-9679191 0.504942 0.297 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 0.505737 0.296 0 0
Platelet activation, signaling and aggregation R-HSA-76002 0.506963 0.295 0 0
Co-inhibition by PD-1 R-HSA-389948 0.509114 0.293 0 0
GABA receptor activation R-HSA-977443 0.509445 0.293 0 0
RET signaling R-HSA-8853659 0.511489 0.291 0 0
HSF1 activation R-HSA-3371511 0.511489 0.291 0 0
GPVI-mediated activation cascade R-HSA-114604 0.511489 0.291 0 0
RUNX2 regulates bone development R-HSA-8941326 0.511489 0.291 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 0.512289 0.290 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 0.512289 0.290 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 0.512289 0.290 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 0.512289 0.290 0 0
FGFR3c ligand binding and activation R-HSA-190372 0.512289 0.290 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 0.512289 0.290 0 0
Hydrolysis of LPC R-HSA-1483115 0.512289 0.290 0 0
Regulation of KIT signaling R-HSA-1433559 0.512289 0.290 0 0
Acyl chain remodeling of CL R-HSA-1482798 0.512289 0.290 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 0.512289 0.290 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 0.517289 0.286 0 0
Aquaporin-mediated transport R-HSA-445717 0.519154 0.285 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 0.523713 0.281 0 0
Degradation of DVL R-HSA-4641258 0.523713 0.281 0 0
Ovarian tumor domain proteases R-HSA-5689896 0.523713 0.281 0 0
Cell junction organization R-HSA-446728 0.525651 0.279 0 0
Reproduction R-HSA-1474165 0.525739 0.279 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 0.529525 0.276 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 0.531372 0.275 0 0
G beta:gamma signalling through BTK R-HSA-8964315 0.531372 0.275 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 0.531372 0.275 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 0.531372 0.275 0 0
Erythropoietin activates RAS R-HSA-9027284 0.531372 0.275 0 0
FGFR3 ligand binding and activation R-HSA-190239 0.531372 0.275 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 0.531372 0.275 0 0
Synthesis of 12-eicosatetraenoic acid derivatives R-HSA-2142712 0.531372 0.275 0 0
p38MAPK events R-HSA-171007 0.531372 0.275 0 0
Spry regulation of FGF signaling R-HSA-1295596 0.531372 0.275 0 0
Interleukin-12 family signaling R-HSA-447115 0.532600 0.274 0 0
PPARA activates gene expression R-HSA-1989781 0.535598 0.271 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 0.535730 0.271 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 0.535730 0.271 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 0.535730 0.271 0 0
Stabilization of p53 R-HSA-69541 0.547536 0.262 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 0.547536 0.262 0 0
Insulin receptor signalling cascade R-HSA-74751 0.547641 0.262 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 0.547649 0.261 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 0.549710 0.260 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 0.549710 0.260 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 0.549710 0.260 0 0
Killing mechanisms R-HSA-9664420 0.549710 0.260 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 0.549710 0.260 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 0.549710 0.260 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 0.549710 0.260 0 0
Prolonged ERK activation events R-HSA-169893 0.549710 0.260 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 0.549710 0.260 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 0.549710 0.260 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 0.549710 0.260 0 0
Negative regulation of FLT3 R-HSA-9706369 0.549710 0.260 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 0.549710 0.260 0 0
Adaptive Immune System R-HSA-1280218 0.556638 0.254 0 0
Cellular response to hypoxia R-HSA-1234174 0.556914 0.254 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 0.559130 0.252 0 0
Interleukin-2 family signaling R-HSA-451927 0.559130 0.252 0 0
Glycogen metabolism R-HSA-8982491 0.559130 0.252 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 0.564307 0.248 0 0
Innate Immune System R-HSA-168249 0.567144 0.246 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 0.567331 0.246 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 0.567331 0.246 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 0.567331 0.246 0 0
Scavenging by Class B Receptors R-HSA-3000471 0.567331 0.246 0 0
Vitamin B6 activation to pyridoxal phosphate R-HSA-964975 0.567331 0.246 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 0.567331 0.246 0 0
Passive transport by Aquaporins R-HSA-432047 0.567331 0.246 0 0
Fibronectin matrix formation R-HSA-1566977 0.567331 0.246 0 0
Galactose catabolism R-HSA-70370 0.567331 0.246 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 0.570511 0.244 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 0.570511 0.244 0 0
PKMTs methylate histone lysines R-HSA-3214841 0.570511 0.244 0 0
FLT3 Signaling R-HSA-9607240 0.570511 0.244 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 0.571053 0.243 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 0.575114 0.240 0 0
Kidney development R-HSA-9830369 0.575114 0.240 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 0.577353 0.239 0 0
G alpha (q) signalling events R-HSA-416476 0.579372 0.237 0 0
MAP2K and MAPK activation R-HSA-5674135 0.581678 0.235 0 0
Signaling by FGFR1 in disease R-HSA-5655302 0.581678 0.235 0 0
Translation of Structural Proteins R-HSA-9683701 0.581678 0.235 0 0
Signaling by Hedgehog R-HSA-5358351 0.583607 0.234 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 0.584037 0.234 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 0.584263 0.233 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 0.584263 0.233 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 0.584263 0.233 0 0
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770 0.584263 0.233 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 0.584263 0.233 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 0.584263 0.233 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 0.584263 0.233 0 0
Developmental Biology R-HSA-1266738 0.587787 0.231 0 0
Signaling by NOTCH R-HSA-157118 0.588252 0.230 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 0.592629 0.227 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 0.592629 0.227 0 0
Cilium Assembly R-HSA-5617833 0.593570 0.227 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 0.595277 0.225 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 0.600534 0.221 0 0
GAB1 signalosome R-HSA-180292 0.600534 0.221 0 0
Activated point mutants of FGFR2 R-HSA-2033519 0.600534 0.221 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 0.600534 0.221 0 0
Mismatch Repair R-HSA-5358508 0.600534 0.221 0 0
Transport of connexons to the plasma membrane R-HSA-190872 0.600534 0.221 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 0.600534 0.221 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 0.600534 0.221 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 0.600534 0.221 0 0
Tie2 Signaling R-HSA-210993 0.600534 0.221 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 0.601521 0.221 0 0
Defective pyroptosis R-HSA-9710421 0.603365 0.219 0 0
TBC/RABGAPs R-HSA-8854214 0.603365 0.219 0 0
Response of Mtb to phagocytosis R-HSA-9637690 0.603365 0.219 0 0
Homology Directed Repair R-HSA-5693538 0.605181 0.218 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 0.610080 0.215 0 0
Hedgehog 'on' state R-HSA-5632684 0.610080 0.215 0 0
Cyclin D associated events in G1 R-HSA-69231 0.613885 0.212 0 0
G1 Phase R-HSA-69236 0.613885 0.212 0 0
Netrin-1 signaling R-HSA-373752 0.613885 0.212 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 0.616169 0.210 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 0.616169 0.210 0 0
Regulation of signaling by CBL R-HSA-912631 0.616169 0.210 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 0.616169 0.210 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 0.616169 0.210 0 0
The NLRP3 inflammasome R-HSA-844456 0.616169 0.210 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 0.616169 0.210 0 0
Mitotic Prophase R-HSA-68875 0.618308 0.209 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 0.624191 0.205 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 0.624191 0.205 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 0.631194 0.200 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 0.631194 0.200 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 0.631194 0.200 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 0.631194 0.200 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 0.631194 0.200 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 0.631194 0.200 0 0
Acyl chain remodelling of PI R-HSA-1482922 0.631194 0.200 0 0
Formation of definitive endoderm R-HSA-9823730 0.631194 0.200 0 0
Protein hydroxylation R-HSA-9629569 0.631194 0.200 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 0.631194 0.200 0 0
Glycogen synthesis R-HSA-3322077 0.631194 0.200 0 0
Regulation of insulin secretion R-HSA-422356 0.631807 0.199 0 0
G alpha (s) signalling events R-HSA-418555 0.633279 0.198 0 0
Regulation of pyruvate metabolism R-HSA-9861718 0.634282 0.198 1 1
Signaling by ERBB4 R-HSA-1236394 0.635010 0.197 0 0
HATs acetylate histones R-HSA-3214847 0.638854 0.195 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 0.638854 0.195 0 0
Protein ubiquitination R-HSA-8852135 0.643069 0.192 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 0.643069 0.192 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 0.644161 0.191 0 0
Recycling pathway of L1 R-HSA-437239 0.644161 0.191 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 0.645630 0.190 0 0
G-protein activation R-HSA-202040 0.645630 0.190 0 0
FGFR2 ligand binding and activation R-HSA-190241 0.645630 0.190 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 0.645630 0.190 0 0
ERK/MAPK targets R-HSA-198753 0.645630 0.190 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 0.645630 0.190 0 0
Acyl chain remodelling of PG R-HSA-1482925 0.645630 0.190 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 0.645630 0.190 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 0.645630 0.190 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 0.646734 0.189 0 0
UCH proteinases R-HSA-5689603 0.651002 0.186 0 0
Intraflagellar transport R-HSA-5620924 0.653827 0.185 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 0.658809 0.181 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 0.659503 0.181 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 0.659503 0.181 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 0.659503 0.181 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 0.659503 0.181 0 0
Eicosanoids R-HSA-211979 0.659503 0.181 0 0
Miscellaneous substrates R-HSA-211958 0.659503 0.181 0 0
Glutathione synthesis and recycling R-HSA-174403 0.659503 0.181 0 0
Signaling by PDGFR in disease R-HSA-9671555 0.659503 0.181 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 0.663282 0.178 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 0.663282 0.178 0 0
Signaling by Nuclear Receptors R-HSA-9006931 0.664600 0.177 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 0.665812 0.177 0 0
PI3K Cascade R-HSA-109704 0.672529 0.172 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 0.672833 0.172 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 0.672833 0.172 0 0
FGFR2 alternative splicing R-HSA-6803529 0.672833 0.172 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 0.672833 0.172 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 0.672833 0.172 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 0.672833 0.172 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 0.672833 0.172 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 0.672833 0.172 0 0
rRNA processing R-HSA-72312 0.674230 0.171 0 0
Protein localization R-HSA-9609507 0.676681 0.170 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 0.681569 0.166 0 0
Meiotic recombination R-HSA-912446 0.681569 0.166 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 0.681569 0.166 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 0.685643 0.164 0 0
Interleukin receptor SHC signaling R-HSA-912526 0.685643 0.164 0 0
Fatty acids R-HSA-211935 0.685643 0.164 0 0
Carnitine shuttle R-HSA-200425 0.685643 0.164 0 0
Formation of the ureteric bud R-HSA-9830674 0.685643 0.164 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 0.685643 0.164 0 0
Growth hormone receptor signaling R-HSA-982772 0.685643 0.164 0 0
Cell-Cell communication R-HSA-1500931 0.688140 0.162 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 0.688768 0.162 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 0.690403 0.161 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 0.690403 0.161 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 0.697951 0.156 0 0
Deadenylation of mRNA R-HSA-429947 0.697951 0.156 0 0
Complex III assembly R-HSA-9865881 0.697951 0.156 0 0
TNFs bind their physiological receptors R-HSA-5669034 0.697951 0.156 0 0
Regulation of PTEN stability and activity R-HSA-8948751 0.699035 0.156 0 0
Organelle biogenesis and maintenance R-HSA-1852241 0.703189 0.153 0 0
Antigen processing-Cross presentation R-HSA-1236975 0.704385 0.152 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 0.709778 0.149 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 0.709778 0.149 0 0
G protein gated Potassium channels R-HSA-1296059 0.709778 0.149 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 0.709778 0.149 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 0.709778 0.149 0 0
HDMs demethylate histones R-HSA-3214842 0.709778 0.149 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 0.709778 0.149 0 0
Laminin interactions R-HSA-3000157 0.709778 0.149 0 0
Interleukin-7 signaling R-HSA-1266695 0.709778 0.149 0 0
Transmission across Chemical Synapses R-HSA-112315 0.714180 0.146 0 0
G alpha (z) signalling events R-HSA-418597 0.715700 0.145 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 0.721143 0.142 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 0.721143 0.142 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 0.721143 0.142 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 0.721143 0.142 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 0.721143 0.142 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 0.721143 0.142 0 0
Suppression of phagosomal maturation R-HSA-9637687 0.721143 0.142 0 0
IRS-mediated signalling R-HSA-112399 0.731583 0.136 0 0
Signaling by FGFR3 in disease R-HSA-5655332 0.732064 0.135 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 0.732064 0.135 0 0
Cristae formation R-HSA-8949613 0.732064 0.135 0 0
Triglyceride biosynthesis R-HSA-75109 0.732064 0.135 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 0.732064 0.135 0 0
Maturation of hRSV A proteins R-HSA-9828806 0.732064 0.135 0 0
Hemostasis R-HSA-109582 0.737317 0.132 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 0.739238 0.131 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 0.742557 0.129 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 0.742557 0.129 0 0
Inflammasomes R-HSA-622312 0.742557 0.129 0 0
mRNA Splicing - Major Pathway R-HSA-72163 0.744736 0.128 0 0
Peroxisomal protein import R-HSA-9033241 0.746706 0.127 0 0
ER-Phagosome pathway R-HSA-1236974 0.748858 0.126 0 0
Late endosomal microautophagy R-HSA-9615710 0.752640 0.123 0 0
Signaling by Erythropoietin R-HSA-9006335 0.752640 0.123 0 0
Termination of translesion DNA synthesis R-HSA-5656169 0.752640 0.123 0 0
Platelet calcium homeostasis R-HSA-418360 0.752640 0.123 0 0
DARPP-32 events R-HSA-180024 0.752640 0.123 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 0.755619 0.122 0 0
Interferon alpha/beta signaling R-HSA-909733 0.755619 0.122 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 0.760874 0.119 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 0.761092 0.119 0 0
Formation of paraxial mesoderm R-HSA-9793380 0.761092 0.119 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 0.762329 0.118 0 0
Activation of BH3-only proteins R-HSA-114452 0.762329 0.118 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 0.762329 0.118 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 0.762329 0.118 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 0.762329 0.118 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 0.763864 0.117 0 0
Mitochondrial biogenesis R-HSA-1592230 0.766024 0.116 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 0.768016 0.115 0 0
Heme signaling R-HSA-9707616 0.768016 0.115 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 0.768016 0.115 0 0
EGFR downregulation R-HSA-182971 0.771639 0.113 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 0.771639 0.113 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 0.771639 0.113 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 0.771639 0.113 0 0
Molecules associated with elastic fibres R-HSA-2129379 0.771639 0.113 0 0
Signaling by Insulin receptor R-HSA-74752 0.772419 0.112 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 0.774765 0.111 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 0.778019 0.109 0 0
G0 and Early G1 R-HSA-1538133 0.780584 0.108 0 0
Inwardly rectifying K+ channels R-HSA-1296065 0.780584 0.108 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 0.780584 0.108 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 0.781178 0.107 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 0.781341 0.107 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 0.782022 0.107 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 0.785791 0.105 0 0
mRNA Splicing R-HSA-72172 0.788727 0.103 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 0.788879 0.103 0 0
Activation of ATR in response to replication stress R-HSA-176187 0.789180 0.103 0 0
G-protein beta:gamma signalling R-HSA-397795 0.789180 0.103 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 0.789180 0.103 0 0
Cardiogenesis R-HSA-9733709 0.789180 0.103 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 0.789180 0.103 0 0
Gastrulation R-HSA-9758941 0.794920 0.100 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 0.795165 0.100 0 0
Acyl chain remodelling of PC R-HSA-1482788 0.797440 0.098 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 0.797440 0.098 0 0
Miscellaneous transport and binding events R-HSA-5223345 0.797440 0.098 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 0.799294 0.097 0 0
Host Interactions of HIV factors R-HSA-162909 0.799726 0.097 0 0
Nicotinate metabolism R-HSA-196807 0.800070 0.097 0 0
Epigenetic regulation of gene expression R-HSA-212165 0.804621 0.094 0 0
Dual Incision in GG-NER R-HSA-5696400 0.805376 0.094 0 0
eNOS activation R-HSA-203615 0.805376 0.094 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 0.805376 0.094 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 0.805376 0.094 0 0
NOD1/2 Signaling Pathway R-HSA-168638 0.805376 0.094 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 0.805376 0.094 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 0.805376 0.094 0 0
Gap junction assembly R-HSA-190861 0.805376 0.094 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 0.805376 0.094 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 0.805376 0.094 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 0.805376 0.094 0 0
Signaling by NOTCH2 R-HSA-1980145 0.805376 0.094 0 0
G1/S Transition R-HSA-69206 0.808603 0.092 0 0
Post-translational protein phosphorylation R-HSA-8957275 0.809276 0.092 0 0
Cellular response to chemical stress R-HSA-9711123 0.810454 0.091 0 0
Acyl chain remodelling of PE R-HSA-1482839 0.813002 0.090 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 0.813002 0.090 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 0.813002 0.090 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 0.813002 0.090 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 0.815078 0.089 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 0.817363 0.088 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 0.817363 0.088 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 0.820330 0.086 0 0
RNA Polymerase III Transcription R-HSA-74158 0.820330 0.086 0 0
FGFR2 mutant receptor activation R-HSA-1839126 0.820330 0.086 0 0
FLT3 signaling in disease R-HSA-9682385 0.820330 0.086 0 0
Glycosphingolipid transport R-HSA-9845576 0.820330 0.086 0 0
G1/S-Specific Transcription R-HSA-69205 0.820330 0.086 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 0.822823 0.085 0 0
Ubiquinol biosynthesis R-HSA-2142789 0.827371 0.082 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 0.827371 0.082 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 0.827371 0.082 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 0.827371 0.082 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 0.828136 0.082 0 0
Purine catabolism R-HSA-74259 0.828136 0.082 0 0
DNA Repair R-HSA-73894 0.828139 0.082 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 0.830037 0.081 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 0.834136 0.079 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 0.834136 0.079 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 0.834136 0.079 0 0
Purine salvage R-HSA-74217 0.834136 0.079 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 0.834136 0.079 0 0
Elastic fibre formation R-HSA-1566948 0.834136 0.079 0 0
Adherens junctions interactions R-HSA-418990 0.836172 0.078 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 0.836736 0.077 0 0
Signaling by FGFR in disease R-HSA-1226099 0.838333 0.077 0 0
Signaling by NOTCH4 R-HSA-9013694 0.838333 0.077 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 0.840637 0.075 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 0.840637 0.075 0 0
RAS processing R-HSA-9648002 0.840637 0.075 0 0
Circadian clock R-HSA-9909396 0.840949 0.075 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 0.843224 0.074 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 0.843224 0.074 0 0
Generation of second messenger molecules R-HSA-202433 0.846883 0.072 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 0.846883 0.072 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 0.846883 0.072 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 0.846883 0.072 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 0.847980 0.072 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 0.851826 0.070 1 0
Translation of Structural Proteins R-HSA-9694635 0.852605 0.069 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 0.852885 0.069 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 0.852885 0.069 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 0.852885 0.069 0 0
RNA Polymerase I Transcription R-HSA-73864 0.857101 0.067 0 0
Cholesterol biosynthesis R-HSA-191273 0.857101 0.067 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 0.857466 0.067 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 0.858652 0.066 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 0.858652 0.066 0 0
DNA Replication Pre-Initiation R-HSA-69002 0.860721 0.065 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 0.864193 0.063 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 0.864193 0.063 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 0.864193 0.063 0 0
TCR signaling R-HSA-202403 0.864403 0.063 0 0
Signaling by SCF-KIT R-HSA-1433557 0.869517 0.061 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 0.869746 0.061 0 0
FCERI mediated MAPK activation R-HSA-2871796 0.871512 0.060 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 0.873859 0.059 0 0
Gap junction trafficking R-HSA-190828 0.874633 0.058 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 0.874633 0.058 0 0
Amine ligand-binding receptors R-HSA-375280 0.874633 0.058 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 0.874800 0.058 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 0.874942 0.058 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 0.876670 0.057 0 0
Signaling by ROBO receptors R-HSA-376176 0.876670 0.057 0 0
Metabolism of steroids R-HSA-8957322 0.879042 0.056 0 0
Nucleosome assembly R-HSA-774815 0.879548 0.056 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 0.879548 0.056 0 0
Somitogenesis R-HSA-9824272 0.879548 0.056 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 0.879548 0.056 0 0
Chromatin modifying enzymes R-HSA-3247509 0.879597 0.056 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 0.880301 0.055 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 0.880301 0.055 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 0.881312 0.055 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 0.881542 0.055 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 0.881559 0.055 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 0.884272 0.053 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 0.884272 0.053 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 0.884749 0.053 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 0.885219 0.053 0 0
SARS-CoV-1 Infection R-HSA-9678108 0.885594 0.053 0 0
Keratinization R-HSA-6805567 0.886637 0.052 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 0.887862 0.052 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 0.888790 0.051 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 0.888810 0.051 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 0.888810 0.051 0 0
Synthesis of PC R-HSA-1483191 0.888810 0.051 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 0.888810 0.051 0 0
Gluconeogenesis R-HSA-70263 0.893170 0.049 0 0
NGF-stimulated transcription R-HSA-9031628 0.893170 0.049 0 0
Metal ion SLC transporters R-HSA-425410 0.893170 0.049 0 0
Glucose metabolism R-HSA-70326 0.893864 0.049 0 0
S Phase R-HSA-69242 0.897232 0.047 0 0
DNA Damage Bypass R-HSA-73893 0.897360 0.047 0 0
Gap junction trafficking and regulation R-HSA-157858 0.897360 0.047 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 0.897360 0.047 0 0
Metabolism of vitamins and cofactors R-HSA-196854 0.898604 0.046 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 0.899576 0.046 0 0
Signaling by FGFR2 in disease R-HSA-5655253 0.901386 0.045 0 0
Downstream TCR signaling R-HSA-202424 0.905149 0.043 0 0
Base Excision Repair R-HSA-73884 0.905149 0.043 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 0.908970 0.041 0 0
mRNA 3'-end processing R-HSA-72187 0.908970 0.041 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 0.908970 0.041 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 0.911041 0.040 0 0
Chromatin organization R-HSA-4839726 0.911176 0.040 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 0.912541 0.040 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 0.912541 0.040 0 0
Amino acids regulate mTORC1 R-HSA-9639288 0.912541 0.040 0 0
Nucleotide biosynthesis R-HSA-8956320 0.912541 0.040 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 0.913856 0.039 0 0
Cell-cell junction organization R-HSA-421270 0.914798 0.039 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 0.919269 0.037 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 0.919754 0.036 0 0
Cellular response to starvation R-HSA-9711097 0.920242 0.036 0 0
Platelet degranulation R-HSA-114608 0.921997 0.035 0 0
Interferon gamma signaling R-HSA-877300 0.922269 0.035 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 0.922436 0.035 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 0.922436 0.035 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 0.922436 0.035 0 0
Signaling by TGFB family members R-HSA-9006936 0.924249 0.034 0 0
Eukaryotic Translation Termination R-HSA-72764 0.924303 0.034 0 0
Dectin-2 family R-HSA-5621480 0.925480 0.034 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 0.926722 0.033 0 0
Dual incision in TC-NER R-HSA-6782135 0.928404 0.032 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 0.928404 0.032 0 0
SARS-CoV-2-host interactions R-HSA-9705683 0.930038 0.031 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 0.931214 0.031 0 0
Triglyceride metabolism R-HSA-8979227 0.931214 0.031 0 0
Regulation of beta-cell development R-HSA-186712 0.931214 0.031 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 0.931214 0.031 0 0
Extension of Telomeres R-HSA-180786 0.931214 0.031 0 0
Glutathione conjugation R-HSA-156590 0.933913 0.030 0 0
tRNA Aminoacylation R-HSA-379724 0.933913 0.030 0 0
Degradation of the extracellular matrix R-HSA-1474228 0.934297 0.030 0 0
Signaling by GPCR R-HSA-372790 0.935007 0.029 0 0
Glycolysis R-HSA-70171 0.935686 0.029 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 0.936164 0.029 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 0.936507 0.028 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 0.936507 0.028 0 0
Nucleotide salvage R-HSA-8956321 0.936507 0.028 0 0
Collagen degradation R-HSA-1442490 0.936507 0.028 0 0
GPCR downstream signalling R-HSA-388396 0.937340 0.028 0 0
tRNA processing in the nucleus R-HSA-6784531 0.938999 0.027 0 0
Regulation of endogenous retroelements R-HSA-9842860 0.939768 0.027 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 0.943604 0.025 0 0
RSV-host interactions R-HSA-9833110 0.945434 0.024 0 0
Nucleotide Excision Repair R-HSA-5696398 0.947207 0.024 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 0.947582 0.023 0 0
Leishmania parasite growth and survival R-HSA-9664433 0.947582 0.023 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 0.948028 0.023 0 0
Gene Silencing by RNA R-HSA-211000 0.950590 0.022 0 0
Synthesis of DNA R-HSA-69239 0.950590 0.022 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 0.953571 0.021 0 0
G alpha (i) signalling events R-HSA-418594 0.954422 0.020 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 0.955723 0.020 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 0.955723 0.020 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 0.956606 0.019 0 0
ECM proteoglycans R-HSA-3000178 0.957462 0.019 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 0.957462 0.019 0 0
Regulation of mitotic cell cycle R-HSA-453276 0.957462 0.019 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 0.958166 0.019 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 0.958166 0.019 0 0
Inositol phosphate metabolism R-HSA-1483249 0.958166 0.019 0 0
SARS-CoV-2 Infection R-HSA-9694516 0.958255 0.019 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 0.959132 0.018 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 0.959132 0.018 0 0
Interferon Signaling R-HSA-913531 0.960734 0.017 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 0.960738 0.017 0 0
Switching of origins to a post-replicative state R-HSA-69052 0.960738 0.017 0 0
Transport of vitamins, nucleosides, and related molecules R-HSA-425397 0.962280 0.017 0 0
ROS and RNS production in phagocytes R-HSA-1222556 0.962280 0.017 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 0.963761 0.016 0 0
Arachidonate metabolism R-HSA-2142753 0.965640 0.015 0 0
Asparagine N-linked glycosylation R-HSA-446203 0.965992 0.015 0 0
DNA Replication R-HSA-69306 0.966659 0.015 0 0
PCP/CE pathway R-HSA-4086400 0.967867 0.014 0 0
SLC-mediated transport of organic anions R-HSA-9955298 0.967867 0.014 0 0
Integrin cell surface interactions R-HSA-216083 0.967867 0.014 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 0.968613 0.014 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 0.969129 0.014 0 0
Signaling by MET R-HSA-6806834 0.970342 0.013 0 0
SARS-CoV Infections R-HSA-9679506 0.970638 0.013 0 0
Chromosome Maintenance R-HSA-73886 0.971111 0.013 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 0.971111 0.013 0 0
Amyloid fiber formation R-HSA-977225 0.971508 0.013 0 0
HCMV Early Events R-HSA-9609690 0.972087 0.012 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 0.972627 0.012 0 0
Cytoprotection by HMOX1 R-HSA-9707564 0.973703 0.012 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 0.973703 0.012 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 0.974737 0.011 0 0
Peroxisomal lipid metabolism R-HSA-390918 0.974737 0.011 0 0
Metabolism of nucleotides R-HSA-15869 0.975237 0.011 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 0.977600 0.010 0 0
Nucleotide catabolism R-HSA-8956319 0.978741 0.009 0 0
Peptide chain elongation R-HSA-156902 0.979327 0.009 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 0.979327 0.009 0 0
Sensory perception of taste R-HSA-9717189 0.980821 0.008 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 0.980921 0.008 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 0.981671 0.008 0 0
Eukaryotic Translation Elongation R-HSA-156842 0.983084 0.007 0 0
FCGR activation R-HSA-2029481 0.983749 0.007 0 0
Assembly of the pre-replicative complex R-HSA-68867 0.983749 0.007 0 0
Mitochondrial protein degradation R-HSA-9837999 0.984389 0.007 0 0
Collagen formation R-HSA-1474290 0.984389 0.007 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 0.984716 0.007 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 0.985003 0.007 0 0
Respiratory electron transport R-HSA-611105 0.985017 0.007 0 0
Influenza Infection R-HSA-168255 0.985480 0.006 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 0.985593 0.006 0 0
Formation of a pool of free 40S subunits R-HSA-72689 0.985593 0.006 0 0
Extracellular matrix organization R-HSA-1474244 0.986471 0.006 0 0
Telomere Maintenance R-HSA-157579 0.986704 0.006 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 0.986704 0.006 0 0
Neddylation R-HSA-8951664 0.986744 0.006 0 0
Synthesis of bile acids and bile salts R-HSA-192105 0.987730 0.005 0 0
Peptide ligand-binding receptors R-HSA-375276 0.988356 0.005 0 0
FCERI mediated NF-kB activation R-HSA-2871837 0.988590 0.005 0 0
Selenocysteine synthesis R-HSA-2408557 0.988676 0.005 0 0
HIV Infection R-HSA-162906 0.988885 0.005 0 0
Viral mRNA Translation R-HSA-192823 0.989550 0.005 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 0.990356 0.004 0 0
Activation of HOX genes during differentiation R-HSA-5619507 0.990356 0.004 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 0.990749 0.004 0 0
SARS-CoV-1-host interactions R-HSA-9692914 0.991101 0.004 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 0.991375 0.004 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 0.991451 0.004 0 0
Cell surface interactions at the vascular wall R-HSA-202733 0.991739 0.004 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 0.991788 0.004 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 0.991788 0.004 0 0
Bile acid and bile salt metabolism R-HSA-194068 0.992422 0.003 0 0
Antimicrobial peptides R-HSA-6803157 0.992720 0.003 0 0
Post-translational protein modification R-HSA-597592 0.993399 0.003 0 0
HCMV Infection R-HSA-9609646 0.994415 0.002 0 0
Eukaryotic Translation Initiation R-HSA-72613 0.994505 0.002 0 0
Cap-dependent Translation Initiation R-HSA-72737 0.994505 0.002 0 0
Metabolism of RNA R-HSA-8953854 0.994647 0.002 0 0
Peptide hormone metabolism R-HSA-2980736 0.994722 0.002 0 0
tRNA processing R-HSA-72306 0.995595 0.002 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 0.995853 0.002 0 0
Regulation of Complement cascade R-HSA-977606 0.996173 0.002 0 0
Transport of small molecules R-HSA-382551 0.997965 0.001 0 0
Ribosome-associated quality control R-HSA-9948299 0.997990 0.001 0 0
Late Phase of HIV Life Cycle R-HSA-162599 0.998356 0.001 0 0
Complement cascade R-HSA-166658 0.998543 0.001 0 0
Bacterial Infection Pathways R-HSA-9824439 0.999055 0.000 0 0
HCMV Late Events R-HSA-9610379 0.999102 0.000 0 0
HIV Life Cycle R-HSA-162587 0.999102 0.000 0 0
Viral Infection Pathways R-HSA-9824446 0.999233 0.000 0 0
GPCR ligand binding R-HSA-500792 0.999248 0.000 0 0
Selenoamino acid metabolism R-HSA-2408522 0.999323 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 0.999400 0.000 0 0
SLC transporter disorders R-HSA-5619102 0.999400 0.000 0 0
Fatty acid metabolism R-HSA-8978868 0.999428 0.000 0 0
Diseases of glycosylation R-HSA-3781865 0.999710 0.000 0 0
Metabolism of lipids R-HSA-556833 0.999823 0.000 0 0
Disease R-HSA-1643685 0.999829 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 0.999919 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 0.999954 0.000 0 0
Infectious disease R-HSA-5663205 0.999960 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 0.999968 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 0.999970 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 0.999978 0.000 0 0
Diseases of metabolism R-HSA-5668914 0.999997 0.000 0 0
Translation R-HSA-72766 0.999998 0.000 0 0
Metabolism of proteins R-HSA-392499 0.999998 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000 0.000 0 0
Biological oxidations R-HSA-211859 1.000000 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000 0.000 0 0
Metabolism R-HSA-1430728 1.000000 0.000 1 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
DNA methylation R-HSA-5334118 1.110223e-16 15.955 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.110223e-16 15.955 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.110223e-16 15.955 0 0
HCMV Early Events R-HSA-9609690 1.110223e-16 15.955 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.110223e-16 15.955 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.110223e-16 15.955 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.110223e-16 15.955 0 0
Mitotic Prophase R-HSA-68875 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Cell Cycle R-HSA-1640170 1.110223e-16 15.955 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Cell-Cell communication R-HSA-1500931 1.110223e-16 15.955 0 0
Cellular Senescence R-HSA-2559583 1.110223e-16 15.955 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cell junction organization R-HSA-446728 2.220446e-16 15.654 0 0
Developmental Biology R-HSA-1266738 2.220446e-16 15.654 0 0
PRC2 methylates histones and DNA R-HSA-212300 3.330669e-16 15.477 0 0
Cell Cycle, Mitotic R-HSA-69278 3.330669e-16 15.477 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 7.771561e-16 15.109 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 8.881784e-16 15.051 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.332268e-15 14.875 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.665335e-15 14.778 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.887379e-15 14.724 0 0
Viral Infection Pathways R-HSA-9824446 2.109424e-15 14.676 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 2.442491e-15 14.612 0 0
HCMV Infection R-HSA-9609646 3.774758e-15 14.423 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 6.550316e-15 14.184 0 0
Defective pyroptosis R-HSA-9710421 7.549517e-15 14.122 0 0
Meiotic recombination R-HSA-912446 1.032507e-14 13.986 0 0
Packaging Of Telomere Ends R-HSA-171306 1.065814e-14 13.972 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.153833e-14 13.667 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.231548e-14 13.651 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 3.019807e-14 13.520 0 0
HDACs deacetylate histones R-HSA-3214815 3.586020e-14 13.445 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 4.862777e-14 13.313 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 4.862777e-14 13.313 0 0
Gene Silencing by RNA R-HSA-211000 7.438494e-14 13.129 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 8.426593e-14 13.074 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 9.958701e-14 13.002 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.227907e-13 12.911 0 0
Meiosis R-HSA-1500620 1.253442e-13 12.902 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 1.513234e-13 12.820 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.513234e-13 12.820 0 0
Nucleosome assembly R-HSA-774815 1.687539e-13 12.773 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.687539e-13 12.773 0 0
Meiotic synapsis R-HSA-1221632 1.959544e-13 12.708 0 0
RNA Polymerase I Transcription R-HSA-73864 1.977307e-13 12.704 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.354783e-13 12.628 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 3.016476e-13 12.521 0 0
Diseases of programmed cell death R-HSA-9645723 3.022027e-13 12.520 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 3.289591e-13 12.483 0 0
HATs acetylate histones R-HSA-3214847 6.042944e-13 12.219 0 0
Eukaryotic Translation Elongation R-HSA-156842 8.582024e-13 12.066 0 0
Cleavage of the damaged purine R-HSA-110331 9.915402e-13 12.004 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.078138e-12 11.967 0 0
Chromosome Maintenance R-HSA-73886 1.331379e-12 11.876 0 0
Depurination R-HSA-73927 1.406653e-12 11.852 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.855516e-12 11.732 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.950662e-12 11.710 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 2.293832e-12 11.639 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 2.416845e-12 11.617 0 0
Telomere Maintenance R-HSA-157579 2.783107e-12 11.555 0 0
Cap-dependent Translation Initiation R-HSA-72737 3.473777e-12 11.459 0 0
Eukaryotic Translation Initiation R-HSA-72613 3.473777e-12 11.459 0 0
Adherens junctions interactions R-HSA-418990 3.680611e-12 11.434 0 0
Estrogen-dependent gene expression R-HSA-9018519 4.013123e-12 11.397 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.895861e-12 11.310 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.642598e-12 11.249 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 7.174483e-12 11.144 0 0
Depyrimidination R-HSA-73928 7.174483e-12 11.144 0 0
Cell-cell junction organization R-HSA-421270 7.305601e-12 11.136 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 8.623102e-12 11.064 0 0
Infectious disease R-HSA-5663205 1.619649e-11 10.791 0 0
L1CAM interactions R-HSA-373760 2.052103e-11 10.688 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 2.666423e-11 10.574 0 0
Recycling pathway of L1 R-HSA-437239 3.084810e-11 10.511 0 0
Reproduction R-HSA-1474165 4.218881e-11 10.375 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 4.576961e-11 10.339 0 0
Metabolism of RNA R-HSA-8953854 4.466649e-11 10.350 0 0
Assembly of the pre-replicative complex R-HSA-68867 4.734024e-11 10.325 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 5.317435e-11 10.274 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 7.538881e-11 10.123 0 0
Transport of connexons to the plasma membrane R-HSA-190872 7.557732e-11 10.122 0 0
Post NMDA receptor activation events R-HSA-438064 8.508916e-11 10.070 0 0
Peptide chain elongation R-HSA-156902 1.023944e-10 9.990 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 1.167482e-10 9.933 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.297579e-10 9.887 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.391305e-10 9.857 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.391305e-10 9.857 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.630016e-10 9.788 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.885482e-10 9.725 0 0
Regulation of endogenous retroelements R-HSA-9842860 2.626399e-10 9.581 0 0
Influenza Infection R-HSA-168255 2.914522e-10 9.535 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 2.944363e-10 9.531 0 0
Interleukin-12 signaling R-HSA-9020591 3.895101e-10 9.409 0 0
Activation of HOX genes during differentiation R-HSA-5619507 4.239988e-10 9.373 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 4.239988e-10 9.373 0 0
ESR-mediated signaling R-HSA-8939211 4.675390e-10 9.330 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 5.227733e-10 9.282 0 0
G2/M Checkpoints R-HSA-69481 6.557891e-10 9.183 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 6.744960e-10 9.171 0 0
Amyloid fiber formation R-HSA-977225 9.936795e-10 9.003 0 0
Gap junction trafficking R-HSA-190828 1.119792e-09 8.951 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.282416e-09 8.892 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.443628e-09 8.841 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.503302e-09 8.823 0 0
Apoptotic execution phase R-HSA-75153 1.849479e-09 8.733 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 2.036353e-09 8.691 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 2.678697e-09 8.572 0 0
Aggrephagy R-HSA-9646399 2.681023e-09 8.572 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.992435e-09 8.524 0 0
SARS-CoV-1-host interactions R-HSA-9692914 3.172663e-09 8.499 0 0
Interleukin-12 family signaling R-HSA-447115 3.338046e-09 8.477 0 0
Ribosome-associated quality control R-HSA-9948299 3.516789e-09 8.454 0 0
Striated Muscle Contraction R-HSA-390522 3.568972e-09 8.447 0 0
Gap junction trafficking and regulation R-HSA-157858 3.778851e-09 8.423 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 3.820628e-09 8.418 0 0
PKR-mediated signaling R-HSA-9833482 5.236787e-09 8.281 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 6.368993e-09 8.196 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 6.368993e-09 8.196 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.399080e-09 8.131 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.399080e-09 8.131 0 0
TCF dependent signaling in response to WNT R-HSA-201681 7.985126e-09 8.098 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 8.128205e-09 8.090 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.053577e-08 7.977 0 0
Cell Cycle Checkpoints R-HSA-69620 1.113554e-08 7.953 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.207674e-08 7.918 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.368829e-08 7.864 0 0
Apoptosis R-HSA-109581 1.376317e-08 7.861 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.586728e-08 7.799 0 0
Eukaryotic Translation Termination R-HSA-72764 1.586728e-08 7.799 0 0
Chromatin modifying enzymes R-HSA-3247509 1.838898e-08 7.735 0 0
Immune System R-HSA-168256 1.860294e-08 7.730 0 0
DNA Replication R-HSA-69306 2.208601e-08 7.656 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 2.258807e-08 7.646 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 2.459080e-08 7.609 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 2.565520e-08 7.591 0 0
Base Excision Repair R-HSA-73884 3.057350e-08 7.515 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 3.135246e-08 7.504 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.477764e-08 7.459 0 0
Selenocysteine synthesis R-HSA-2408557 3.719478e-08 7.430 0 0
Gap junction assembly R-HSA-190861 4.387225e-08 7.358 0 0
Viral mRNA Translation R-HSA-192823 4.880014e-08 7.312 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 5.068666e-08 7.295 0 0
Chromatin organization R-HSA-4839726 6.308486e-08 7.200 0 0
Programmed Cell Death R-HSA-5357801 6.943077e-08 7.158 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 7.904684e-08 7.102 0 0
Signaling by WNT R-HSA-195721 7.231417e-08 7.141 0 0
Mitotic Prometaphase R-HSA-68877 8.012020e-08 7.096 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.255226e-08 7.083 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.534554e-08 7.021 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.012382e-07 6.995 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.063177e-07 6.973 0 0
HCMV Late Events R-HSA-9610379 1.366938e-07 6.864 0 0
Co-inhibition by PD-1 R-HSA-389948 1.484740e-07 6.828 0 0
Translation R-HSA-72766 1.743147e-07 6.759 0 0
Mitotic Anaphase R-HSA-68882 1.761025e-07 6.754 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.910791e-07 6.719 0 0
Signaling by ROBO receptors R-HSA-376176 1.918211e-07 6.717 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.967754e-07 6.706 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.021671e-07 6.694 0 0
Protein folding R-HSA-391251 2.455792e-07 6.610 0 0
EPH-Ephrin signaling R-HSA-2682334 2.455792e-07 6.610 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.484390e-07 6.605 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.484390e-07 6.605 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.484390e-07 6.605 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 2.493024e-07 6.603 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 4.151530e-07 6.382 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 4.356569e-07 6.361 0 0
Cell-extracellular matrix interactions R-HSA-446353 5.491346e-07 6.260 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 5.491346e-07 6.260 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 5.544216e-07 6.256 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 5.565031e-07 6.255 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 5.619096e-07 6.250 0 0
Cellular response to starvation R-HSA-9711097 5.814303e-07 6.236 0 0
Signal Transduction R-HSA-162582 5.926960e-07 6.227 0 0
Disease R-HSA-1643685 6.036014e-07 6.219 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 6.146347e-07 6.211 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 6.286878e-07 6.202 0 0
DNA Double Strand Break Response R-HSA-5693606 7.592968e-07 6.120 0 0
Signaling downstream of RAS mutants R-HSA-9649948 7.911083e-07 6.102 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 7.911083e-07 6.102 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 7.911083e-07 6.102 0 0
Signaling by RAS mutants R-HSA-6802949 7.911083e-07 6.102 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.551910e-07 6.020 0 0
Separation of Sister Chromatids R-HSA-2467813 1.000670e-06 6.000 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.081207e-06 5.966 0 0
Signaling by NOTCH R-HSA-157118 1.102269e-06 5.958 0 0
Signaling by RAF1 mutants R-HSA-9656223 2.057509e-06 5.687 0 0
Neutrophil degranulation R-HSA-6798695 1.960907e-06 5.708 0 0
rRNA processing R-HSA-72312 1.951849e-06 5.710 0 0
G2/M Transition R-HSA-69275 1.964721e-06 5.707 0 0
Mitotic G2-G2/M phases R-HSA-453274 2.301993e-06 5.638 0 0
Ub-specific processing proteases R-HSA-5689880 2.347305e-06 5.629 0 0
SARS-CoV-1 Infection R-HSA-9678108 2.763333e-06 5.559 0 0
Selective autophagy R-HSA-9663891 3.043305e-06 5.517 0 0
Epigenetic regulation of gene expression R-HSA-212165 3.093057e-06 5.510 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 3.254028e-06 5.488 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 3.254028e-06 5.488 0 0
Glycolysis R-HSA-70171 3.474782e-06 5.459 0 0
RMTs methylate histone arginines R-HSA-3214858 3.598863e-06 5.444 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 3.967221e-06 5.402 0 0
Signaling by Nuclear Receptors R-HSA-9006931 4.027105e-06 5.395 0 0
Muscle contraction R-HSA-397014 4.605898e-06 5.337 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 5.043590e-06 5.297 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 5.356024e-06 5.271 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 6.010840e-06 5.221 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 6.671137e-06 5.176 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 6.671137e-06 5.176 0 0
Kinesins R-HSA-983189 8.073002e-06 5.093 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 8.171568e-06 5.088 0 0
Oncogenic MAPK signaling R-HSA-6802957 8.685013e-06 5.061 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 8.706100e-06 5.060 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.063176e-06 5.043 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 9.527246e-06 5.021 0 0
Cellular response to heat stress R-HSA-3371556 9.964180e-06 5.002 0 0
Interferon Signaling R-HSA-913531 1.182866e-05 4.927 0 0
Selenoamino acid metabolism R-HSA-2408522 1.214139e-05 4.916 0 0
MAP2K and MAPK activation R-HSA-5674135 1.343956e-05 4.872 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.350350e-05 4.870 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.632285e-05 4.787 0 0
Translation initiation complex formation R-HSA-72649 1.818807e-05 4.740 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 2.057675e-05 4.687 0 0
Regulation of CDH1 Function R-HSA-9764561 2.783512e-05 4.555 0 0
Glucose metabolism R-HSA-70326 2.592150e-05 4.586 0 0
Deubiquitination R-HSA-5688426 2.509685e-05 4.600 0 0
Homology Directed Repair R-HSA-5693538 2.835292e-05 4.547 0 0
mRNA Splicing - Major Pathway R-HSA-72163 3.560898e-05 4.448 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 3.617886e-05 4.442 0 0
Metabolism of proteins R-HSA-392499 3.659467e-05 4.437 0 0
Gluconeogenesis R-HSA-70263 4.105975e-05 4.387 0 0
Transmission across Chemical Synapses R-HSA-112315 5.430103e-05 4.265 0 0
Autophagy R-HSA-9612973 6.984299e-05 4.156 0 0
mRNA Splicing R-HSA-72172 7.187265e-05 4.143 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.844886e-05 4.105 0 0
Cilium Assembly R-HSA-5617833 8.082303e-05 4.092 0 0
Developmental Cell Lineages R-HSA-9734767 1.038907e-04 3.983 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.069006e-04 3.971 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.143659e-04 3.942 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.216547e-04 3.915 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.243528e-04 3.905 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.377068e-04 3.861 0 0
Long-term potentiation R-HSA-9620244 1.428510e-04 3.845 0 0
COPI-mediated anterograde transport R-HSA-6807878 1.522446e-04 3.817 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.628875e-04 3.788 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.747323e-04 3.758 0 0
Ephrin signaling R-HSA-3928664 1.984144e-04 3.702 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.984144e-04 3.702 0 0
Intraflagellar transport R-HSA-5620924 2.141672e-04 3.669 0 0
Macroautophagy R-HSA-1632852 2.193102e-04 3.659 0 0
Protein ubiquitination R-HSA-8852135 2.330575e-04 3.633 0 0
UCH proteinases R-HSA-5689603 2.576929e-04 3.589 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 2.606358e-04 3.584 0 0
Organelle biogenesis and maintenance R-HSA-1852241 2.704629e-04 3.568 0 0
Semaphorin interactions R-HSA-373755 2.763429e-04 3.559 0 0
Signaling by Interleukins R-HSA-449147 2.945902e-04 3.531 0 0
Membrane Trafficking R-HSA-199991 3.106792e-04 3.508 0 0
Activation of BH3-only proteins R-HSA-114452 3.500289e-04 3.456 0 0
RAF/MAP kinase cascade R-HSA-5673001 3.694098e-04 3.432 0 0
Smooth Muscle Contraction R-HSA-445355 3.964465e-04 3.402 0 0
MHC class II antigen presentation R-HSA-2132295 4.865359e-04 3.313 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 4.887782e-04 3.311 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 5.044079e-04 3.297 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 5.099022e-04 3.293 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 5.445507e-04 3.264 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 5.571798e-04 3.254 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 6.492162e-04 3.188 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 7.946446e-04 3.100 0 0
Protein methylation R-HSA-8876725 6.492162e-04 3.188 0 0
Platelet degranulation R-HSA-114608 6.861130e-04 3.164 0 0
Hemostasis R-HSA-109582 6.624085e-04 3.179 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 8.011314e-04 3.096 0 0
MAPK family signaling cascades R-HSA-5683057 8.231209e-04 3.085 0 0
Adaptive Immune System R-HSA-1280218 8.955430e-04 3.048 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 9.000591e-04 3.046 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.082422e-04 3.042 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.010987e-03 2.995 0 0
Metalloprotease DUBs R-HSA-5689901 1.103518e-03 2.957 0 0
Signaling by Hippo R-HSA-2028269 1.239633e-03 2.907 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.288825e-03 2.890 0 0
DNA Repair R-HSA-73894 1.336679e-03 2.874 0 0
Neuronal System R-HSA-112316 1.597134e-03 2.797 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 1.729847e-03 2.762 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 1.898413e-03 2.722 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.989175e-03 2.701 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.989175e-03 2.701 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.989175e-03 2.701 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.276858e-03 2.643 0 0
Platelet activation, signaling and aggregation R-HSA-76002 2.283826e-03 2.641 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 2.303759e-03 2.638 0 0
Hedgehog 'off' state R-HSA-5610787 2.385444e-03 2.622 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 2.728735e-03 2.564 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.842505e-03 2.546 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.844913e-03 2.546 0 0
SARS-CoV Infections R-HSA-9679506 3.023827e-03 2.519 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 3.052256e-03 2.515 0 0
mTORC1-mediated signalling R-HSA-166208 3.486565e-03 2.458 0 0
RAF activation R-HSA-5673000 3.749682e-03 2.426 0 0
Nuclear import of Rev protein R-HSA-180746 3.749682e-03 2.426 0 0
Signaling by Hedgehog R-HSA-5358351 4.164006e-03 2.380 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 4.208258e-03 2.376 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.234293e-03 2.373 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 4.279206e-03 2.369 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 4.279206e-03 2.369 0 0
HSF1 activation R-HSA-3371511 4.706981e-03 2.327 0 0
Manipulation of host energy metabolism R-HSA-9636667 5.246649e-03 2.280 0 0
Breakdown of the nuclear lamina R-HSA-352238 5.246649e-03 2.280 0 0
AURKA Activation by TPX2 R-HSA-8854518 5.444423e-03 2.264 0 0
Vesicle-mediated transport R-HSA-5653656 5.566528e-03 2.254 0 0
HSF1-dependent transactivation R-HSA-3371571 5.593168e-03 2.252 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 5.659480e-03 2.247 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 6.206693e-03 2.207 0 0
ER to Golgi Anterograde Transport R-HSA-199977 6.869814e-03 2.163 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 9.112787e-03 2.040 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 9.112787e-03 2.040 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 9.112787e-03 2.040 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 9.112787e-03 2.040 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 9.112787e-03 2.040 0 0
Type I hemidesmosome assembly R-HSA-446107 7.340042e-03 2.134 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 7.340042e-03 2.134 0 0
Formation of annular gap junctions R-HSA-196025 7.340042e-03 2.134 0 0
Gap junction degradation R-HSA-190873 9.286010e-03 2.032 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 8.233437e-03 2.084 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 7.143598e-03 2.146 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 9.094131e-03 2.041 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 7.143598e-03 2.146 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 8.484193e-03 2.071 0 0
GP1b-IX-V activation signalling R-HSA-430116 9.286010e-03 2.032 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 8.484193e-03 2.071 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 7.025288e-03 2.153 0 0
SARS-CoV-2 Infection R-HSA-9694516 7.349558e-03 2.134 0 0
Chaperone Mediated Autophagy R-HSA-9613829 9.570199e-03 2.019 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 9.713012e-03 2.013 0 0
Centrosome maturation R-HSA-380287 1.041139e-02 1.982 0 0
Trafficking of AMPA receptors R-HSA-399719 1.087840e-02 1.963 0 0
Host Interactions of HIV factors R-HSA-162909 1.137208e-02 1.944 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.150539e-02 1.939 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.150539e-02 1.939 0 0
Signaling by ERBB2 R-HSA-1227986 1.157932e-02 1.936 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.204855e-02 1.919 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.264898e-02 1.898 0 0
Nephrin family interactions R-HSA-373753 1.264898e-02 1.898 0 0
Protein hydroxylation R-HSA-9629569 1.264898e-02 1.898 0 0
Signal transduction by L1 R-HSA-445144 1.264898e-02 1.898 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.284539e-02 1.891 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.337635e-02 1.874 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.434032e-02 1.843 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.434032e-02 1.843 0 0
Signaling by PTK6 R-HSA-8848021 1.434032e-02 1.843 0 0
Basigin interactions R-HSA-210991 1.439978e-02 1.842 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.629674e-02 1.788 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.629674e-02 1.788 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 1.629674e-02 1.788 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.629674e-02 1.788 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 1.739446e-02 1.760 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.823983e-02 1.739 0 0
FGFR2 alternative splicing R-HSA-6803529 1.834329e-02 1.737 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.957527e-02 1.708 0 0
MTF1 activates gene expression R-HSA-5660489 1.957527e-02 1.708 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.993755e-02 1.700 0 0
Syndecan interactions R-HSA-3000170 2.054247e-02 1.687 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 2.123963e-02 1.673 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.277650e-02 1.643 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 2.289696e-02 1.640 0 0
Neurodegenerative Diseases R-HSA-8863678 2.289696e-02 1.640 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.310782e-02 1.636 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 2.394475e-02 1.621 0 0
HIV Life Cycle R-HSA-162587 2.415210e-02 1.617 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 2.507908e-02 1.601 0 0
HDMs demethylate histones R-HSA-3214842 2.540903e-02 1.595 0 0
Sema4D in semaphorin signaling R-HSA-400685 2.540903e-02 1.595 0 0
Regulation of MITF-M dependent genes involved in invasion R-HSA-9854909 2.603657e-02 1.584 0 0
Malate-aspartate shuttle R-HSA-9856872 2.686211e-02 1.571 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.690449e-02 1.570 0 0
Attenuation phase R-HSA-3371568 2.715507e-02 1.566 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 2.715507e-02 1.566 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 2.786629e-02 1.555 0 0
Signaling by ALK in cancer R-HSA-9700206 2.786629e-02 1.555 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.787293e-02 1.555 0 0
Myogenesis R-HSA-525793 2.808060e-02 1.552 0 0
Signaling by ERBB4 R-HSA-1236394 2.847377e-02 1.546 0 0
PKMTs methylate histone lysines R-HSA-3214841 2.933732e-02 1.533 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.933732e-02 1.533 0 0
Signaling by VEGF R-HSA-194138 2.963079e-02 1.528 0 0
Innate Immune System R-HSA-168249 3.061718e-02 1.514 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.068281e-02 1.513 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 3.079631e-02 1.512 0 0
DCC mediated attractive signaling R-HSA-418885 3.079631e-02 1.512 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 3.079631e-02 1.512 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 3.091322e-02 1.510 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 3.091322e-02 1.510 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.162720e-02 1.500 0 0
HIV Infection R-HSA-162906 3.260096e-02 1.487 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 3.323386e-02 1.478 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 3.323386e-02 1.478 0 0
MTOR signalling R-HSA-165159 3.402592e-02 1.468 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 3.501589e-02 1.456 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 3.501589e-02 1.456 0 0
Sensory processing of sound R-HSA-9659379 3.724919e-02 1.429 0 0
Viral Messenger RNA Synthesis R-HSA-168325 3.793827e-02 1.421 0 0
Recycling of eIF2:GDP R-HSA-72731 4.960429e-02 1.304 0 0
Disinhibition of SNARE formation R-HSA-114516 4.960429e-02 1.304 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 4.960429e-02 1.304 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 3.951777e-02 1.403 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 4.429800e-02 1.354 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 4.429800e-02 1.354 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 4.429800e-02 1.354 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 4.935186e-02 1.307 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 4.038735e-02 1.394 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 4.387247e-02 1.358 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 4.387247e-02 1.358 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.133278e-02 1.290 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 5.133278e-02 1.290 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 5.530673e-02 1.257 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 5.530673e-02 1.257 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 4.472838e-02 1.349 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 4.328482e-02 1.364 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 4.188509e-02 1.378 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 5.780875e-02 1.238 0 0
Rap1 signalling R-HSA-392517 5.467391e-02 1.262 0 0
CHL1 interactions R-HSA-447041 4.960429e-02 1.304 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 5.530673e-02 1.257 0 0
Response of endothelial cells to shear stress R-HSA-9860931 5.479550e-02 1.261 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 4.960429e-02 1.304 0 0
Signaling by TGFBR3 R-HSA-9839373 4.472838e-02 1.349 0 0
STING mediated induction of host immune responses R-HSA-1834941 5.467391e-02 1.262 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 5.133278e-02 1.290 0 0
Post-translational protein modification R-HSA-597592 4.002787e-02 1.398 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 4.472838e-02 1.349 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 5.042813e-02 1.297 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 5.437852e-02 1.265 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 5.836208e-02 1.234 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 5.866919e-02 1.232 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 5.866919e-02 1.232 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 5.866919e-02 1.232 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 5.944188e-02 1.226 0 0
Formation of definitive endoderm R-HSA-9823730 6.025809e-02 1.220 0 0
Late Phase of HIV Life Cycle R-HSA-162599 6.175084e-02 1.209 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 6.373692e-02 1.196 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 6.416097e-02 1.193 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 6.609781e-02 1.180 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 6.609781e-02 1.180 0 0
Early Phase of HIV Life Cycle R-HSA-162594 6.609781e-02 1.180 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 6.819024e-02 1.166 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 6.819024e-02 1.166 0 0
Calmodulin induced events R-HSA-111933 6.819024e-02 1.166 0 0
CaM pathway R-HSA-111997 6.819024e-02 1.166 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 6.825334e-02 1.166 0 0
ALK mutants bind TKIs R-HSA-9700645 6.825334e-02 1.166 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 6.825334e-02 1.166 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 6.825334e-02 1.166 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 6.825334e-02 1.166 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 6.825334e-02 1.166 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 6.835055e-02 1.165 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 6.835055e-02 1.165 0 0
Diseases of Telomere Maintenance R-HSA-9673013 6.835055e-02 1.165 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 6.835055e-02 1.165 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 6.835055e-02 1.165 0 0
Inhibition of PKR R-HSA-169131 6.835055e-02 1.165 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 7.062883e-02 1.151 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 7.131512e-02 1.147 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 7.218597e-02 1.142 0 0
Signaling by NOTCH4 R-HSA-9013694 7.391060e-02 1.131 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 7.497461e-02 1.125 0 0
ISG15 antiviral mechanism R-HSA-1169408 7.727803e-02 1.112 0 0
Binding and entry of HIV virion R-HSA-173107 7.830977e-02 1.106 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 7.830977e-02 1.106 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 7.830977e-02 1.106 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 7.851507e-02 1.105 0 0
Gene expression (Transcription) R-HSA-74160 8.174527e-02 1.088 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 8.248031e-02 1.084 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 8.248031e-02 1.084 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 8.248031e-02 1.084 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 8.252805e-02 1.083 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 8.754607e-02 1.058 0 0
PCP/CE pathway R-HSA-4086400 8.789096e-02 1.056 0 0
snRNP Assembly R-HSA-191859 9.192381e-02 1.037 0 0
Metabolism of non-coding RNA R-HSA-194441 9.192381e-02 1.037 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 9.235311e-02 1.035 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 9.275870e-02 1.033 0 0
RAB geranylgeranylation R-HSA-8873719 9.632406e-02 1.016 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 9.762380e-02 1.010 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.886787e-02 1.005 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 9.886787e-02 1.005 0 0
Interleukin-7 signaling R-HSA-1266695 9.886787e-02 1.005 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 9.966476e-02 1.001 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 9.966476e-02 1.001 0 0
Integration of provirus R-HSA-162592 9.966476e-02 1.001 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 9.966476e-02 1.001 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 9.966476e-02 1.001 0 0
Interactions of Tat with host cellular proteins R-HSA-176034 1.007564e-01 0.997 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 1.007564e-01 0.997 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.007564e-01 0.997 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 1.007564e-01 0.997 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.026960e-01 0.988 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 1.036129e-01 0.985 0 0
Ca-dependent events R-HSA-111996 1.036129e-01 0.985 0 0
Signaling by TGFB family members R-HSA-9006936 1.049868e-01 0.979 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.054382e-01 0.977 0 0
tRNA processing in the nucleus R-HSA-6784531 1.054382e-01 0.977 0 0
Signaling by EGFR in Cancer R-HSA-1643713 1.060793e-01 0.974 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.064808e-01 0.973 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.092481e-01 0.962 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.104051e-01 0.957 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.108821e-01 0.955 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.108821e-01 0.955 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.134897e-01 0.945 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.134897e-01 0.945 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 1.134897e-01 0.945 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.134897e-01 0.945 0 0
Opioid Signalling R-HSA-111885 1.174202e-01 0.930 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 1.174202e-01 0.930 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 1.320369e-01 0.879 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 1.320369e-01 0.879 0 0
Potassium transport channels R-HSA-1296067 1.320369e-01 0.879 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 1.913769e-01 0.718 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 1.913769e-01 0.718 0 0
Signaling by MAP2K mutants R-HSA-9652169 1.913769e-01 0.718 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.913769e-01 0.718 0 0
IRS activation R-HSA-74713 2.195103e-01 0.659 0 0
G2 Phase R-HSA-68911 2.195103e-01 0.659 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.195103e-01 0.659 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.195103e-01 0.659 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 2.195103e-01 0.659 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 2.195103e-01 0.659 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 1.709423e-01 0.767 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 1.709423e-01 0.767 0 0
HIV elongation arrest and recovery R-HSA-167287 1.210902e-01 0.917 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.210902e-01 0.917 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 1.962492e-01 0.707 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.090712e-01 0.680 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.219748e-01 0.654 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.349390e-01 0.629 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.655709e-01 0.781 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 1.723806e-01 0.764 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 2.238332e-01 0.650 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.198357e-01 0.921 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.198357e-01 0.921 0 0
HIV Transcription Elongation R-HSA-167169 2.330882e-01 0.632 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 2.330882e-01 0.632 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 2.330882e-01 0.632 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 1.862818e-01 0.730 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 1.933647e-01 0.714 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 1.933647e-01 0.714 0 0
Dual incision in TC-NER R-HSA-6782135 2.077739e-01 0.682 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 1.788542e-01 0.748 0 0
Integrin signaling R-HSA-354192 1.616267e-01 0.791 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.532118e-01 0.815 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 1.512985e-01 0.820 0 0
Regulation of mitotic cell cycle R-HSA-453276 1.512985e-01 0.820 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.965531e-01 0.707 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 2.349390e-01 0.629 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 1.792857e-01 0.746 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 2.195103e-01 0.659 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 1.709423e-01 0.767 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 1.962492e-01 0.707 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 2.238332e-01 0.650 0 0
G alpha (z) signalling events R-HSA-418597 1.862818e-01 0.730 0 0
Degradation of CDH1 R-HSA-9766229 1.457554e-01 0.836 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 2.090712e-01 0.680 0 0
Stabilization of p53 R-HSA-69541 2.238332e-01 0.650 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 1.320369e-01 0.879 0 0
MET interacts with TNS proteins R-HSA-8875513 1.622312e-01 0.790 0 0
Fibronectin matrix formation R-HSA-1566977 1.709423e-01 0.767 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 2.090712e-01 0.680 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.055574e-01 0.687 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 1.534808e-01 0.814 0 0
G alpha (12/13) signalling events R-HSA-416482 1.917725e-01 0.717 0 0
Frs2-mediated activation R-HSA-170968 1.224090e-01 0.912 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 1.709423e-01 0.767 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.090712e-01 0.680 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 1.457554e-01 0.836 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 1.457554e-01 0.836 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 2.146535e-01 0.668 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 1.288717e-01 0.890 0 0
ERK/MAPK targets R-HSA-198753 2.349390e-01 0.629 0 0
Prolonged ERK activation events R-HSA-169893 1.585072e-01 0.800 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 1.933647e-01 0.714 0 0
Leishmania phagocytosis R-HSA-9664417 1.967606e-01 0.706 0 0
Parasite infection R-HSA-9664407 1.967606e-01 0.706 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 1.967606e-01 0.706 0 0
Hedgehog ligand biogenesis R-HSA-5358346 1.588607e-01 0.799 0 0
Regulation of PTEN gene transcription R-HSA-8943724 2.224791e-01 0.653 0 0
The NLRP3 inflammasome R-HSA-844456 2.090712e-01 0.680 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 2.238332e-01 0.650 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.917725e-01 0.717 0 0
Intracellular oxygen transport R-HSA-8981607 1.622312e-01 0.790 0 0
NADE modulates death signalling R-HSA-205025 1.913769e-01 0.718 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 1.224090e-01 0.912 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 2.330882e-01 0.632 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 2.330882e-01 0.632 0 0
Signalling to ERKs R-HSA-187687 1.876491e-01 0.727 0 0
Mitochondrial protein degradation R-HSA-9837999 1.666415e-01 0.778 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.055574e-01 0.687 0 0
NRAGE signals death through JNK R-HSA-193648 1.933647e-01 0.714 0 0
Extracellular matrix organization R-HSA-1474244 1.856195e-01 0.731 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.515876e-01 0.819 0 0
Activation, myristolyation of BID and translocation to mitochondria R-HSA-75108 1.320369e-01 0.879 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.195103e-01 0.659 0 0
Regulation of KIT signaling R-HSA-1433559 1.342104e-01 0.872 0 0
MAP kinase activation R-HSA-450294 2.299320e-01 0.638 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 1.876491e-01 0.727 0 0
G-protein mediated events R-HSA-112040 1.299798e-01 0.886 0 0
RNA Polymerase II Transcription R-HSA-73857 2.137126e-01 0.670 0 0
Toxicity of tetanus toxin (tetX) R-HSA-5250982 1.913769e-01 0.718 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 2.195103e-01 0.659 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 2.195103e-01 0.659 0 0
Signal regulatory protein family interactions R-HSA-391160 1.342104e-01 0.872 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.219748e-01 0.654 0 0
Signaling by FGFR2 R-HSA-5654738 2.039841e-01 0.690 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 2.005302e-01 0.698 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.467461e-01 0.833 0 0
Signaling by NTRKs R-HSA-166520 1.391285e-01 0.857 0 0
Generic Transcription Pathway R-HSA-212436 1.356650e-01 0.868 0 0
Creatine metabolism R-HSA-71288 2.219748e-01 0.654 0 0
Pentose phosphate pathway R-HSA-71336 2.238332e-01 0.650 0 0
DAG and IP3 signaling R-HSA-1489509 1.209183e-01 0.918 0 0
PLC beta mediated events R-HSA-112043 2.299320e-01 0.638 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.180116e-01 0.662 0 0
Signaling by FGFR R-HSA-190236 1.925470e-01 0.715 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 2.349390e-01 0.629 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.498262e-01 0.824 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 1.655709e-01 0.781 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 1.701771e-01 0.769 0 0
Specification of primordial germ cells R-HSA-9827857 1.835316e-01 0.736 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.224090e-01 0.912 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.979042e-01 0.704 0 0
Response to metal ions R-HSA-5660526 1.709423e-01 0.767 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.241873e-01 0.906 0 0
IRE1alpha activates chaperones R-HSA-381070 1.518590e-01 0.819 0 0
FOXO-mediated transcription R-HSA-9614085 1.979042e-01 0.704 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 2.368449e-01 0.626 0 0
Mitochondrial protein import R-HSA-1268020 2.374462e-01 0.624 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 2.424104e-01 0.615 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.424104e-01 0.615 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 2.424104e-01 0.615 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 2.424104e-01 0.615 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 2.450173e-01 0.611 0 0
Plus-strand DNA synthesis R-HSA-164525 2.466666e-01 0.608 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.466666e-01 0.608 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.466666e-01 0.608 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.466666e-01 0.608 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.466666e-01 0.608 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.466666e-01 0.608 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.466666e-01 0.608 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.466666e-01 0.608 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.466666e-01 0.608 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 2.479440e-01 0.606 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 2.485664e-01 0.605 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 2.489076e-01 0.604 0 0
Metabolism of amino acids and derivatives R-HSA-71291 2.615378e-01 0.582 0 0
Protein localization R-HSA-9609507 2.626310e-01 0.581 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 2.659751e-01 0.575 0 0
MyD88-independent TLR4 cascade R-HSA-166166 2.659751e-01 0.575 0 0
ER-Phagosome pathway R-HSA-1236974 2.683941e-01 0.571 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 2.707031e-01 0.568 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 2.728796e-01 0.564 0 0
Signaling by LTK in cancer R-HSA-9842640 2.728796e-01 0.564 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.728796e-01 0.564 0 0
RUNX3 regulates YAP1-mediated transcription R-HSA-8951671 2.728796e-01 0.564 0 0
Autointegration results in viral DNA circles R-HSA-177539 2.728796e-01 0.564 0 0
Uncoating of the HIV Virion R-HSA-162585 2.728796e-01 0.564 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 2.728796e-01 0.564 0 0
CREB phosphorylation R-HSA-199920 2.728796e-01 0.564 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 2.728796e-01 0.564 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 2.728796e-01 0.564 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 2.728796e-01 0.564 0 0
VLDL assembly R-HSA-8866423 2.728796e-01 0.564 0 0
Neurofascin interactions R-HSA-447043 2.728796e-01 0.564 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 2.740037e-01 0.562 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 2.740037e-01 0.562 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.740037e-01 0.562 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 2.802177e-01 0.553 0 0
Netrin-1 signaling R-HSA-373752 2.802177e-01 0.553 0 0
Deadenylation of mRNA R-HSA-429947 2.870250e-01 0.542 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.870250e-01 0.542 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 2.870250e-01 0.542 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 2.897623e-01 0.538 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 2.897623e-01 0.538 0 0
Interferon gamma signaling R-HSA-877300 2.926967e-01 0.534 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 2.981821e-01 0.526 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 2.981821e-01 0.526 0 0
IFNG signaling activates MAPKs R-HSA-9732724 2.981821e-01 0.526 0 0
SOS-mediated signalling R-HSA-112412 2.981821e-01 0.526 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 2.981821e-01 0.526 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 2.981821e-01 0.526 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 2.981821e-01 0.526 0 0
LDL remodeling R-HSA-8964041 2.981821e-01 0.526 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 2.992640e-01 0.524 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 2.992640e-01 0.524 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.992640e-01 0.524 0 0
Interleukin-17 signaling R-HSA-448424 2.992640e-01 0.524 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 2.993299e-01 0.524 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 2.993299e-01 0.524 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 2.993299e-01 0.524 0 0
TGFBR3 expression R-HSA-9839394 3.000203e-01 0.523 0 0
Laminin interactions R-HSA-3000157 3.000203e-01 0.523 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.000203e-01 0.523 0 0
Tight junction interactions R-HSA-420029 3.000203e-01 0.523 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 3.089139e-01 0.510 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.089733e-01 0.510 0 0
MET activates PTK2 signaling R-HSA-8874081 3.129757e-01 0.504 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 3.129757e-01 0.504 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 3.129757e-01 0.504 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 3.150446e-01 0.502 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 3.150446e-01 0.502 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 3.158266e-01 0.501 0 0
GPER1 signaling R-HSA-9634597 3.185078e-01 0.497 0 0
Mitochondrial biogenesis R-HSA-1592230 3.203800e-01 0.494 0 0
Reverse Transcription of HIV RNA R-HSA-162589 3.226055e-01 0.491 0 0
Minus-strand DNA synthesis R-HSA-164516 3.226055e-01 0.491 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.226055e-01 0.491 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 3.226055e-01 0.491 0 0
FGFR1b ligand binding and activation R-HSA-190370 3.226055e-01 0.491 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.226055e-01 0.491 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.226055e-01 0.491 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 3.226055e-01 0.491 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 3.226055e-01 0.491 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 3.226055e-01 0.491 0 0
Interleukin-23 signaling R-HSA-9020933 3.226055e-01 0.491 0 0
Ca2+ pathway R-HSA-4086398 3.229625e-01 0.491 0 0
Switching of origins to a post-replicative state R-HSA-69052 3.229625e-01 0.491 0 0
Cristae formation R-HSA-8949613 3.258782e-01 0.487 0 0
Insulin processing R-HSA-264876 3.258782e-01 0.487 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.265364e-01 0.486 0 0
DNA Damage Bypass R-HSA-73893 3.281053e-01 0.484 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.332683e-01 0.477 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 3.364910e-01 0.473 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 3.387159e-01 0.470 0 0
Formation of the Early Elongation Complex R-HSA-113418 3.387159e-01 0.470 0 0
Telomere Extension By Telomerase R-HSA-171319 3.387159e-01 0.470 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 3.387159e-01 0.470 0 0
Inflammasomes R-HSA-622312 3.387159e-01 0.470 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 3.388355e-01 0.470 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 3.395592e-01 0.469 0 0
Post-translational protein phosphorylation R-HSA-8957275 3.434060e-01 0.464 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 3.434060e-01 0.464 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 3.434060e-01 0.464 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 3.434060e-01 0.464 0 0
Lipophagy R-HSA-9613354 3.461805e-01 0.461 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.461805e-01 0.461 0 0
ARMS-mediated activation R-HSA-170984 3.461805e-01 0.461 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.461805e-01 0.461 0 0
Regulation of signaling by NODAL R-HSA-1433617 3.461805e-01 0.461 0 0
Calcineurin activates NFAT R-HSA-2025928 3.461805e-01 0.461 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 3.461805e-01 0.461 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.461805e-01 0.461 0 0
Regulated proteolysis of p75NTR R-HSA-193692 3.461805e-01 0.461 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.461805e-01 0.461 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 3.472875e-01 0.459 0 0
The phototransduction cascade R-HSA-2514856 3.472875e-01 0.459 0 0
mRNA Capping R-HSA-72086 3.514777e-01 0.454 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.514777e-01 0.454 0 0
mRNA 3'-end processing R-HSA-72187 3.568607e-01 0.448 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 3.568607e-01 0.448 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 3.568607e-01 0.448 0 0
Orc1 removal from chromatin R-HSA-68949 3.568607e-01 0.448 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 3.568607e-01 0.448 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 3.641533e-01 0.439 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.641533e-01 0.439 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.641987e-01 0.439 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 3.664147e-01 0.436 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 3.664147e-01 0.436 0 0
Nucleotide biosynthesis R-HSA-8956320 3.664147e-01 0.436 0 0
MAPK3 (ERK1) activation R-HSA-110056 3.689363e-01 0.433 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 3.689363e-01 0.433 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.689363e-01 0.433 0 0
Regulation of CDH11 function R-HSA-9762292 3.689363e-01 0.433 0 0
PI3K/AKT activation R-HSA-198203 3.689363e-01 0.433 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.689363e-01 0.433 0 0
Signal attenuation R-HSA-74749 3.689363e-01 0.433 0 0
2-LTR circle formation R-HSA-164843 3.689363e-01 0.433 0 0
Josephin domain DUBs R-HSA-5689877 3.689363e-01 0.433 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 3.689363e-01 0.433 0 0
Signaling by Leptin R-HSA-2586552 3.689363e-01 0.433 0 0
S Phase R-HSA-69242 3.736715e-01 0.428 0 0
EGFR downregulation R-HSA-182971 3.767333e-01 0.424 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 3.767333e-01 0.424 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.767333e-01 0.424 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 3.767333e-01 0.424 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.767333e-01 0.424 0 0
Molecules associated with elastic fibres R-HSA-2129379 3.767333e-01 0.424 0 0
Parasitic Infection Pathways R-HSA-9824443 3.791757e-01 0.421 0 0
Leishmania infection R-HSA-9658195 3.791757e-01 0.421 0 0
Potential therapeutics for SARS R-HSA-9679191 3.850931e-01 0.414 0 0
Signaling by NOTCH3 R-HSA-9012852 3.854446e-01 0.414 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 3.865030e-01 0.413 0 0
G0 and Early G1 R-HSA-1538133 3.892091e-01 0.410 0 0
Inwardly rectifying K+ channels R-HSA-1296065 3.892091e-01 0.410 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 3.892091e-01 0.410 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 3.892091e-01 0.410 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.909016e-01 0.408 0 0
vRNP Assembly R-HSA-192905 3.909016e-01 0.408 0 0
Chylomicron assembly R-HSA-8963888 3.909016e-01 0.408 0 0
Bicarbonate transporters R-HSA-425381 3.909016e-01 0.408 0 0
PECAM1 interactions R-HSA-210990 3.909016e-01 0.408 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 3.909016e-01 0.408 0 0
Dissolution of Fibrin Clot R-HSA-75205 3.909016e-01 0.408 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.949107e-01 0.404 0 0
Ion homeostasis R-HSA-5578775 3.949107e-01 0.404 0 0
Nucleotide Excision Repair R-HSA-5696398 3.988777e-01 0.399 0 0
Nuclear RNA decay R-HSA-9930044 4.015726e-01 0.396 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 4.015726e-01 0.396 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.015726e-01 0.396 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.015726e-01 0.396 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 4.121035e-01 0.385 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 4.121035e-01 0.385 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.121035e-01 0.385 0 0
Plasmalogen biosynthesis R-HSA-75896 4.121035e-01 0.385 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 4.121035e-01 0.385 0 0
Synthesis of DNA R-HSA-69239 4.127080e-01 0.384 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 4.138166e-01 0.383 0 0
Vpu mediated degradation of CD4 R-HSA-180534 4.138166e-01 0.383 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 4.180657e-01 0.379 0 0
Antigen processing-Cross presentation R-HSA-1236975 4.196062e-01 0.377 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 4.196062e-01 0.377 0 0
Extension of Telomeres R-HSA-180786 4.230593e-01 0.374 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 4.230593e-01 0.374 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 4.259025e-01 0.371 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 4.259025e-01 0.371 0 0
Dual Incision in GG-NER R-HSA-5696400 4.259344e-01 0.371 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 4.259344e-01 0.371 0 0
Signal amplification R-HSA-392518 4.259344e-01 0.371 0 0
eNOS activation R-HSA-203615 4.259344e-01 0.371 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 4.259344e-01 0.371 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 4.259344e-01 0.371 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 4.264905e-01 0.370 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.325687e-01 0.364 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.325687e-01 0.364 0 0
Repression of WNT target genes R-HSA-4641265 4.325687e-01 0.364 0 0
GRB2 events in EGFR signaling R-HSA-179812 4.325687e-01 0.364 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.325687e-01 0.364 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.325687e-01 0.364 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 4.325687e-01 0.364 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 4.325687e-01 0.364 0 0
Polymerase switching R-HSA-69091 4.325687e-01 0.364 0 0
Leading Strand Synthesis R-HSA-69109 4.325687e-01 0.364 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.325687e-01 0.364 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 4.325687e-01 0.364 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.325687e-01 0.364 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 4.325687e-01 0.364 0 0
OAS antiviral response R-HSA-8983711 4.325687e-01 0.364 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 4.337125e-01 0.363 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 4.379201e-01 0.359 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 4.379201e-01 0.359 0 0
Oncogene Induced Senescence R-HSA-2559585 4.379201e-01 0.359 0 0
Regulation of Apoptosis R-HSA-169911 4.379201e-01 0.359 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.388192e-01 0.358 0 0
Cellular response to chemical stress R-HSA-9711123 4.414799e-01 0.355 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 4.415756e-01 0.355 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 4.497680e-01 0.347 0 0
RNA Polymerase III Transcription R-HSA-74158 4.497680e-01 0.347 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 4.497680e-01 0.347 0 0
FLT3 signaling in disease R-HSA-9682385 4.497680e-01 0.347 0 0
FGFR2 mutant receptor activation R-HSA-1839126 4.497680e-01 0.347 0 0
RET signaling R-HSA-8853659 4.497680e-01 0.347 0 0
NCAM signaling for neurite out-growth R-HSA-375165 4.507476e-01 0.346 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 4.523227e-01 0.345 0 0
Formation of axial mesoderm R-HSA-9796292 4.523227e-01 0.345 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 4.523227e-01 0.345 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 4.523227e-01 0.345 0 0
FGFR1c ligand binding and activation R-HSA-190373 4.523227e-01 0.345 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 4.523227e-01 0.345 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 4.523227e-01 0.345 0 0
Interleukin-6 signaling R-HSA-1059683 4.523227e-01 0.345 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 4.538517e-01 0.343 0 0
Degradation of DVL R-HSA-4641258 4.614734e-01 0.336 0 0
Degradation of AXIN R-HSA-4641257 4.614734e-01 0.336 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 4.614734e-01 0.336 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 4.674021e-01 0.330 0 0
Removal of the Flap Intermediate R-HSA-69166 4.713902e-01 0.327 0 0
Retrograde neurotrophin signalling R-HSA-177504 4.713902e-01 0.327 0 0
CRMPs in Sema3A signaling R-HSA-399956 4.713902e-01 0.327 0 0
YAP1- and WWTR1 (TAZ)-stimulated gene expression R-HSA-2032785 4.713902e-01 0.327 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 4.713902e-01 0.327 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 4.713902e-01 0.327 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 4.713902e-01 0.327 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.713902e-01 0.327 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 4.713902e-01 0.327 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 4.722726e-01 0.326 0 0
MET promotes cell motility R-HSA-8875878 4.730317e-01 0.325 0 0
Elastic fibre formation R-HSA-1566948 4.730317e-01 0.325 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 4.730317e-01 0.325 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 4.741390e-01 0.324 0 0
PTEN Regulation R-HSA-6807070 4.752745e-01 0.323 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 4.844391e-01 0.315 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 4.844391e-01 0.315 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 4.844391e-01 0.315 0 0
Erythropoietin activates RAS R-HSA-9027284 4.897949e-01 0.310 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 4.897949e-01 0.310 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 4.897949e-01 0.310 0 0
SHC1 events in EGFR signaling R-HSA-180336 4.897949e-01 0.310 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 4.897949e-01 0.310 0 0
G beta:gamma signalling through BTK R-HSA-8964315 4.897949e-01 0.310 0 0
Processive synthesis on the lagging strand R-HSA-69183 4.897949e-01 0.310 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 4.897949e-01 0.310 0 0
p38MAPK events R-HSA-171007 4.897949e-01 0.310 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 4.897949e-01 0.310 0 0
Protein repair R-HSA-5676934 4.897949e-01 0.310 0 0
Spry regulation of FGF signaling R-HSA-1295596 4.897949e-01 0.310 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 4.897949e-01 0.310 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 4.897949e-01 0.310 0 0
Other semaphorin interactions R-HSA-416700 4.897949e-01 0.310 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 4.956920e-01 0.305 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 4.956920e-01 0.305 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 4.956920e-01 0.305 0 0
Collagen formation R-HSA-1474290 5.023995e-01 0.299 0 0
Transcription of the HIV genome R-HSA-167172 5.043683e-01 0.297 0 0
Regulated Necrosis R-HSA-5218859 5.043683e-01 0.297 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 5.067874e-01 0.295 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.067874e-01 0.295 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 5.067874e-01 0.295 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 5.073784e-01 0.295 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 5.073784e-01 0.295 0 0
Phosphorylation of the APC/C R-HSA-176412 5.075600e-01 0.295 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.075600e-01 0.295 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.075600e-01 0.295 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 5.075600e-01 0.295 0 0
Negative regulation of FLT3 R-HSA-9706369 5.075600e-01 0.295 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 5.075600e-01 0.295 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.075600e-01 0.295 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.075600e-01 0.295 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.075600e-01 0.295 0 0
Attachment and Entry R-HSA-9678110 5.075600e-01 0.295 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 5.177226e-01 0.286 0 0
HIV Transcription Initiation R-HSA-167161 5.177226e-01 0.286 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 5.177226e-01 0.286 0 0
Degradation of CRY and PER proteins R-HSA-9932298 5.177226e-01 0.286 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 5.177226e-01 0.286 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 5.177226e-01 0.286 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 5.177226e-01 0.286 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 5.216378e-01 0.283 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.247075e-01 0.280 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.247075e-01 0.280 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 5.247075e-01 0.280 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.247075e-01 0.280 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 5.247075e-01 0.280 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 5.247075e-01 0.280 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 5.247075e-01 0.280 0 0
Coenzyme A biosynthesis R-HSA-196783 5.247075e-01 0.280 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 5.269155e-01 0.278 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 5.269155e-01 0.278 0 0
Activation of GABAB receptors R-HSA-991365 5.284953e-01 0.277 0 0
GABA B receptor activation R-HSA-977444 5.284953e-01 0.277 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.284953e-01 0.277 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 5.284953e-01 0.277 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.333524e-01 0.273 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 5.349343e-01 0.272 0 0
Regulation of insulin secretion R-HSA-422356 5.389548e-01 0.268 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 5.391036e-01 0.268 0 0
Signaling by SCF-KIT R-HSA-1433557 5.391036e-01 0.268 0 0
Response of Mtb to phagocytosis R-HSA-9637690 5.391036e-01 0.268 0 0
Formation of the cornified envelope R-HSA-6809371 5.397495e-01 0.268 0 0
Gastrulation R-HSA-9758941 5.407476e-01 0.267 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 5.412589e-01 0.267 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 5.412589e-01 0.267 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 5.412589e-01 0.267 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 5.412589e-01 0.267 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 5.412589e-01 0.267 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 5.412589e-01 0.267 0 0
Uptake and function of anthrax toxins R-HSA-5210891 5.412589e-01 0.267 0 0
MITF-M-dependent gene expression R-HSA-9856651 5.465293e-01 0.262 0 0
Proteasome assembly R-HSA-9907900 5.495458e-01 0.260 0 0
ABC-family proteins mediated transport R-HSA-382556 5.531923e-01 0.257 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.551627e-01 0.256 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 5.572349e-01 0.254 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 5.572349e-01 0.254 0 0
GAB1 signalosome R-HSA-180292 5.572349e-01 0.254 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 5.572349e-01 0.254 0 0
Presynaptic function of Kainate receptors R-HSA-500657 5.572349e-01 0.254 0 0
Polo-like kinase mediated events R-HSA-156711 5.572349e-01 0.254 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 5.572349e-01 0.254 0 0
FGFR1 ligand binding and activation R-HSA-190242 5.572349e-01 0.254 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 5.572349e-01 0.254 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 5.572349e-01 0.254 0 0
Mismatch Repair R-HSA-5358508 5.572349e-01 0.254 0 0
Cell surface interactions at the vascular wall R-HSA-202733 5.582164e-01 0.253 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 5.598208e-01 0.252 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 5.598208e-01 0.252 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 5.598208e-01 0.252 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 5.598208e-01 0.252 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 5.598208e-01 0.252 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 5.598208e-01 0.252 0 0
Somitogenesis R-HSA-9824272 5.598208e-01 0.252 0 0
Interleukin-1 signaling R-HSA-9020702 5.602231e-01 0.252 0 0
Death Receptor Signaling R-HSA-73887 5.693230e-01 0.245 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 5.699273e-01 0.244 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 5.699273e-01 0.244 0 0
Regulation of signaling by CBL R-HSA-912631 5.726555e-01 0.242 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 5.726555e-01 0.242 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 5.726555e-01 0.242 0 0
Translesion Synthesis by POLH R-HSA-110320 5.726555e-01 0.242 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 5.726555e-01 0.242 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 5.726555e-01 0.242 0 0
Other interleukin signaling R-HSA-449836 5.726555e-01 0.242 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 5.833291e-01 0.234 0 0
Integrin cell surface interactions R-HSA-216083 5.872461e-01 0.231 0 0
ABC transporter disorders R-HSA-5619084 5.872461e-01 0.231 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 5.875399e-01 0.231 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 5.875399e-01 0.231 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 5.875399e-01 0.231 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 5.875399e-01 0.231 0 0
Negative regulation of MET activity R-HSA-6807004 5.875399e-01 0.231 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 5.875399e-01 0.231 0 0
Signaling by NODAL R-HSA-1181150 5.875399e-01 0.231 0 0
RSV-host interactions R-HSA-9833110 5.877327e-01 0.231 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 5.896327e-01 0.229 0 0
NGF-stimulated transcription R-HSA-9031628 5.896327e-01 0.229 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 6.019068e-01 0.220 0 0
G-protein activation R-HSA-202040 6.019068e-01 0.220 0 0
Lagging Strand Synthesis R-HSA-69186 6.019068e-01 0.220 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.019068e-01 0.220 0 0
Signalling to RAS R-HSA-167044 6.019068e-01 0.220 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 6.019068e-01 0.220 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.019068e-01 0.220 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 6.019068e-01 0.220 0 0
Signaling by MET R-HSA-6806834 6.027217e-01 0.220 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.027217e-01 0.220 0 0
Regulation of RAS by GAPs R-HSA-5658442 6.086591e-01 0.216 0 0
Signaling by FGFR2 in disease R-HSA-5655253 6.086591e-01 0.216 0 0
Toll-like Receptor Cascades R-HSA-168898 6.139837e-01 0.212 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 6.157741e-01 0.211 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 6.157741e-01 0.211 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 6.157741e-01 0.211 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 6.157741e-01 0.211 0 0
Serine metabolism R-HSA-977347 6.157741e-01 0.211 0 0
Androgen biosynthesis R-HSA-193048 6.157741e-01 0.211 0 0
Attachment and Entry R-HSA-9694614 6.157741e-01 0.211 0 0
Signaling by PDGFR in disease R-HSA-9671555 6.157741e-01 0.211 0 0
Assembly Of The HIV Virion R-HSA-175474 6.157741e-01 0.211 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 6.179177e-01 0.209 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.291592e-01 0.201 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 6.291592e-01 0.201 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 6.291592e-01 0.201 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 6.291592e-01 0.201 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.291592e-01 0.201 0 0
LDL clearance R-HSA-8964038 6.291592e-01 0.201 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 6.291592e-01 0.201 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.291592e-01 0.201 0 0
Integration of energy metabolism R-HSA-163685 6.302836e-01 0.200 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.325054e-01 0.199 0 0
Regulation of PTEN stability and activity R-HSA-8948751 6.359277e-01 0.197 0 0
Inositol phosphate metabolism R-HSA-1483249 6.396136e-01 0.194 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.420787e-01 0.192 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 6.420787e-01 0.192 0 0
Biosynthesis of maresins R-HSA-9018682 6.420787e-01 0.192 0 0
Formation of the ureteric bud R-HSA-9830674 6.420787e-01 0.192 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 6.420787e-01 0.192 0 0
Growth hormone receptor signaling R-HSA-982772 6.420787e-01 0.192 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.538048e-01 0.185 0 0
CYP2E1 reactions R-HSA-211999 6.545490e-01 0.184 0 0
Thromboxane signalling through TP receptor R-HSA-428930 6.545490e-01 0.184 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 6.545490e-01 0.184 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 6.545490e-01 0.184 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 6.545490e-01 0.184 0 0
Plasma lipoprotein assembly R-HSA-8963898 6.545490e-01 0.184 0 0
Mitochondrial RNA degradation R-HSA-9836573 6.545490e-01 0.184 0 0
Complex III assembly R-HSA-9865881 6.545490e-01 0.184 0 0
Interleukin-6 family signaling R-HSA-6783589 6.545490e-01 0.184 0 0
tRNA processing R-HSA-72306 6.593579e-01 0.181 0 0
Pyruvate metabolism R-HSA-70268 6.607052e-01 0.180 1 0
Signaling by EGFR R-HSA-177929 6.616852e-01 0.179 0 0
Signaling by FGFR1 R-HSA-5654736 6.616852e-01 0.179 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 6.665854e-01 0.176 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 6.665854e-01 0.176 0 0
G protein gated Potassium channels R-HSA-1296059 6.665854e-01 0.176 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 6.665854e-01 0.176 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 6.665854e-01 0.176 0 0
Hyaluronan degradation R-HSA-2160916 6.665854e-01 0.176 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 6.665854e-01 0.176 0 0
Interferon alpha/beta signaling R-HSA-909733 6.697939e-01 0.174 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 6.782033e-01 0.169 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 6.782033e-01 0.169 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 6.782033e-01 0.169 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 6.782033e-01 0.169 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 6.782033e-01 0.169 0 0
TRP channels R-HSA-3295583 6.782033e-01 0.169 0 0
Rab regulation of trafficking R-HSA-9007101 6.813685e-01 0.167 0 0
Peptide hormone metabolism R-HSA-2980736 6.813685e-01 0.167 0 0
Peroxisomal protein import R-HSA-9033241 6.859588e-01 0.164 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 6.859588e-01 0.164 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 6.894169e-01 0.162 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 6.894169e-01 0.162 0 0
Maturation of hRSV A proteins R-HSA-9828806 6.894169e-01 0.162 0 0
GABA receptor activation R-HSA-977443 6.937264e-01 0.159 0 0
Metabolism of polyamines R-HSA-351202 6.937264e-01 0.159 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 7.002405e-01 0.155 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 7.002405e-01 0.155 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 7.002405e-01 0.155 0 0
Pyroptosis R-HSA-5620971 7.002405e-01 0.155 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 7.013347e-01 0.154 0 0
Formation of paraxial mesoderm R-HSA-9793380 7.013347e-01 0.154 0 0
Asparagine N-linked glycosylation R-HSA-446203 7.019800e-01 0.154 0 0
Signaling by Erythropoietin R-HSA-9006335 7.106875e-01 0.148 0 0
Late endosomal microautophagy R-HSA-9615710 7.106875e-01 0.148 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 7.106875e-01 0.148 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.106875e-01 0.148 0 0
Platelet calcium homeostasis R-HSA-418360 7.106875e-01 0.148 0 0
Glucagon-type ligand receptors R-HSA-420092 7.106875e-01 0.148 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 7.106875e-01 0.148 0 0
DARPP-32 events R-HSA-180024 7.106875e-01 0.148 0 0
Activation of the pre-replicative complex R-HSA-68962 7.207711e-01 0.142 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.207711e-01 0.142 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.207711e-01 0.142 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.207711e-01 0.142 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.207711e-01 0.142 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 7.232211e-01 0.141 0 0
Ion transport by P-type ATPases R-HSA-936837 7.232211e-01 0.141 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.283788e-01 0.138 0 0
G1/S Transition R-HSA-69206 7.299054e-01 0.137 0 0
Potassium Channels R-HSA-1296071 7.300450e-01 0.137 0 0
Cellular response to hypoxia R-HSA-1234174 7.302098e-01 0.137 0 0
Budding and maturation of HIV virion R-HSA-162588 7.305037e-01 0.136 0 0
DNA strand elongation R-HSA-69190 7.398978e-01 0.131 0 0
Signaling by WNT in cancer R-HSA-4791275 7.398978e-01 0.131 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 7.417700e-01 0.130 0 0
G-protein beta:gamma signalling R-HSA-397795 7.489649e-01 0.126 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 7.489649e-01 0.126 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.489649e-01 0.126 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 7.489649e-01 0.126 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 7.489649e-01 0.126 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 7.489649e-01 0.126 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 7.502821e-01 0.125 0 0
Regulation of TP53 Activity R-HSA-5633007 7.547195e-01 0.122 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 7.577165e-01 0.120 0 0
Glutamate and glutamine metabolism R-HSA-8964539 7.577165e-01 0.120 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 7.577165e-01 0.120 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 7.577165e-01 0.120 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 7.577165e-01 0.120 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 7.661635e-01 0.116 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 7.661635e-01 0.116 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 7.661635e-01 0.116 0 0
Hyaluronan metabolism R-HSA-2142845 7.661635e-01 0.116 0 0
Signaling by NOTCH2 R-HSA-1980145 7.661635e-01 0.116 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.677945e-01 0.115 0 0
Circadian clock R-HSA-9909396 7.682198e-01 0.115 0 0
ECM proteoglycans R-HSA-3000178 7.690569e-01 0.114 0 0
Hedgehog 'on' state R-HSA-5632684 7.690569e-01 0.114 0 0
PERK regulates gene expression R-HSA-381042 7.743165e-01 0.111 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 7.750367e-01 0.111 0 0
RUNX2 regulates bone development R-HSA-8941326 7.821857e-01 0.107 0 0
G1/S-Specific Transcription R-HSA-69205 7.821857e-01 0.107 0 0
SLC transporter disorders R-HSA-5619102 7.833123e-01 0.106 0 0
Signaling by FGFR in disease R-HSA-1226099 7.865914e-01 0.104 0 0
Voltage gated Potassium channels R-HSA-1296072 7.897810e-01 0.102 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 7.897810e-01 0.102 0 0
Ovarian tumor domain proteases R-HSA-5689896 7.897810e-01 0.102 0 0
Collagen chain trimerization R-HSA-8948216 7.897810e-01 0.102 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 7.921707e-01 0.101 0 0
Stimuli-sensing channels R-HSA-2672351 7.970700e-01 0.099 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 7.971119e-01 0.098 0 0
Plasma lipoprotein clearance R-HSA-8964043 8.041876e-01 0.095 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 8.041876e-01 0.095 0 0
TCR signaling R-HSA-202403 8.060421e-01 0.094 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 8.110169e-01 0.091 0 0
Diseases of Immune System R-HSA-5260271 8.110169e-01 0.091 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 8.110169e-01 0.091 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.110169e-01 0.091 0 0
Generation of second messenger molecules R-HSA-202433 8.110169e-01 0.091 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 8.110169e-01 0.091 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 8.132194e-01 0.090 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 8.176085e-01 0.087 0 0
FLT3 Signaling R-HSA-9607240 8.176085e-01 0.087 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 8.239705e-01 0.084 0 0
Scavenging by Class A Receptors R-HSA-3000480 8.239705e-01 0.084 0 0
Intra-Golgi traffic R-HSA-6811438 8.239705e-01 0.084 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.301110e-01 0.081 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 8.301110e-01 0.081 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 8.319492e-01 0.080 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 8.323442e-01 0.080 0 0
Signaling by FGFR4 R-HSA-5654743 8.360376e-01 0.078 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 8.360376e-01 0.078 0 0
TBC/RABGAPs R-HSA-8854214 8.360376e-01 0.078 0 0
G1 Phase R-HSA-69236 8.417579e-01 0.075 0 0
Cyclin D associated events in G1 R-HSA-69231 8.417579e-01 0.075 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 8.472789e-01 0.072 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 8.472789e-01 0.072 0 0
Signaling by FGFR3 R-HSA-5654741 8.472789e-01 0.072 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 8.496042e-01 0.071 0 0
Interleukin-1 family signaling R-HSA-446652 8.517654e-01 0.070 0 0
Regulation of pyruvate metabolism R-HSA-9861718 8.526076e-01 0.069 1 1
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 8.577508e-01 0.067 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 8.577508e-01 0.067 0 0
Ion channel transport R-HSA-983712 8.592877e-01 0.066 0 0
Plasma lipoprotein remodeling R-HSA-8963899 8.627147e-01 0.064 0 0
Neurotransmitter release cycle R-HSA-112310 8.653795e-01 0.063 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 8.653795e-01 0.063 0 0
Downstream TCR signaling R-HSA-202424 8.653795e-01 0.063 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 8.675057e-01 0.062 0 0
Chemokine receptors bind chemokines R-HSA-380108 8.675057e-01 0.062 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 8.695672e-01 0.061 0 0
PI3K Cascade R-HSA-109704 8.721298e-01 0.059 0 0
Azathioprine ADME R-HSA-9748787 8.721298e-01 0.059 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 8.761487e-01 0.057 0 0
Neurexins and neuroligins R-HSA-6794361 8.809003e-01 0.055 0 0
Amino acids regulate mTORC1 R-HSA-9639288 8.850577e-01 0.053 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 8.923456e-01 0.049 1 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 8.923476e-01 0.049 0 0
Adipogenesis R-HSA-9843745 8.925552e-01 0.049 0 0
Cardiac conduction R-HSA-5576891 8.925552e-01 0.049 0 0
Paracetamol ADME R-HSA-9753281 8.929429e-01 0.049 0 0
Degradation of the extracellular matrix R-HSA-1474228 8.951567e-01 0.048 0 0
IRS-mediated signalling R-HSA-112399 9.002880e-01 0.046 0 0
Keratinization R-HSA-6805567 9.019647e-01 0.045 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.037697e-01 0.044 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.040915e-01 0.044 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.071301e-01 0.042 0 0
tRNA Aminoacylation R-HSA-379724 9.103732e-01 0.041 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 9.103732e-01 0.041 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 9.103732e-01 0.041 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 9.103732e-01 0.041 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 9.103732e-01 0.041 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 9.103732e-01 0.041 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.135034e-01 0.039 0 0
Aquaporin-mediated transport R-HSA-445717 9.135034e-01 0.039 0 0
Collagen degradation R-HSA-1442490 9.135034e-01 0.039 0 0
Heme signaling R-HSA-9707616 9.165244e-01 0.038 0 0
Respiratory electron transport R-HSA-611105 9.181169e-01 0.037 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 9.194400e-01 0.036 0 0
Complex I biogenesis R-HSA-6799198 9.194400e-01 0.036 0 0
Platelet homeostasis R-HSA-418346 9.212993e-01 0.036 0 0
Xenobiotics R-HSA-211981 9.222540e-01 0.035 0 0
Insulin receptor signalling cascade R-HSA-74751 9.222540e-01 0.035 0 0
IGF1R signaling cascade R-HSA-2428924 9.222540e-01 0.035 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.249699e-01 0.034 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.275910e-01 0.033 0 0
Neddylation R-HSA-8951664 9.284621e-01 0.032 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 9.301207e-01 0.031 0 0
Kidney development R-HSA-9830369 9.301207e-01 0.031 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.301207e-01 0.031 0 0
Metabolism of steroid hormones R-HSA-196071 9.301207e-01 0.031 0 0
Visual phototransduction R-HSA-2187338 9.315019e-01 0.031 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.371927e-01 0.028 0 0
Metabolism of cofactors R-HSA-8978934 9.393876e-01 0.027 0 0
Aspirin ADME R-HSA-9749641 9.435502e-01 0.025 0 0
Metabolism of nucleotides R-HSA-15869 9.483926e-01 0.023 0 0
Signaling by NOTCH1 R-HSA-1980143 9.492651e-01 0.023 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.520514e-01 0.021 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.527504e-01 0.021 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.544024e-01 0.020 0 0
Bacterial Infection Pathways R-HSA-9824439 9.547836e-01 0.020 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.575353e-01 0.019 0 0
Protein-protein interactions at synapses R-HSA-6794362 9.631712e-01 0.016 0 0
G alpha (s) signalling events R-HSA-418555 9.643464e-01 0.016 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.662021e-01 0.015 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.662021e-01 0.015 0 0
G alpha (i) signalling events R-HSA-418594 9.670846e-01 0.015 0 0
G alpha (q) signalling events R-HSA-416476 9.727044e-01 0.012 0 0
Signaling by Insulin receptor R-HSA-74752 9.732706e-01 0.012 0 0
Peptide ligand-binding receptors R-HSA-375276 9.762156e-01 0.010 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.776322e-01 0.010 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.786678e-01 0.009 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.822381e-01 0.008 0 0
PPARA activates gene expression R-HSA-1989781 9.847643e-01 0.007 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.856739e-01 0.006 0 0
GPCR downstream signalling R-HSA-388396 9.917915e-01 0.004 0 0
Signaling by GPCR R-HSA-372790 9.964169e-01 0.002 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.967176e-01 0.001 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.967452e-01 0.001 0 0
Drug ADME R-HSA-9748784 9.980320e-01 0.001 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.986190e-01 0.001 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.986210e-01 0.001 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.994760e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.995906e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.997208e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.998661e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999398e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999554e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999595e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999842e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999965e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999998e-01 0.000 0 0
Biological oxidations R-HSA-211859 9.999999e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 1 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways