MST4

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0MZ66 T455 Sugiyama SHTN1 KIAA1598 KPESSKGCEsAVDELKGILGtLNKSTSSRsLKsLDPENsEt
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
B2RPK0 S15 Sugiyama HMGB1P1 HMG1L1 HMGB1L1 ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHSDAS
B2RPK0 T22 Sugiyama HMGB1P1 HMG1L1 HMGB1L1 GKGDPKKPRGKMssyAFFVQtCREEHKKKHSDASVNFSEFS
O00267 T709 Sugiyama SUPT5H SPT5 SPT5H GGSGGMSRGRGRRDNELIGQtVRISQGPYKGYIGVVKDATE
O00303 T119 Sugiyama EIF3F EIF3S5 LASIVDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPH
O00303 T123 Sugiyama EIF3F EIF3S5 VDSYERRNEGAARVIGtLLGtVDKHSVEVTNCFSVPHNEsE
O00429 S44 Sugiyama DNM1L DLP1 DRP1 QLPQIVVVGTQSSGKSsVLEsLVGRDLLPRGTGIVTRRPLI
O00506 S149 Sugiyama STK25 SOK1 YSK1 DYLHsERKIHRDIKAANVLLsEQGDVKLADFGVAGQLtDtQ
O00506 T166 Sugiyama STK25 SOK1 YSK1 VLLsEQGDVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEV
O00506 T168 Sugiyama STK25 SOK1 YSK1 LsEQGDVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEVIK
O00584 T120 Sugiyama RNASET2 RNASE6PL VIHSFPNRSRFWKHEWEKHGtCAAQVDALNSQKKYFGRSLE
O14744 T80 Sugiyama PRMT5 HRMT1L5 IBP72 JBP1 SKB1 KNRPGPQTRSDLLLSGRDWNtLIVGKLSPWIRPDSKVEKIR
O14818 T147 Sugiyama PSMA7 HSPC FGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKS
O14818 T152 Sugiyama PSMA7 HSPC LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL
O14818 Y145 Sugiyama PSMA7 HSPC RPFGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGA
O14829 S6 Sugiyama PPEF1 PPEF PPP7C _______________MGCSSsSTKTRRSDTSLRAALIIQNW
O14908 T238 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 FDMISQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPs
O14908 T242 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 SQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPsAFEE
O14950 T160 Sugiyama MYL12B MRLC2 MYLC2B DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
O15212 T75 Sugiyama PFDN6 HKE2 PFD6 VVFKLLGPVLVKQELGEARAtVGKRLDyItAEIKRYESQLR
O15371 T49 Sugiyama EIF3D EIF3S7 PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY
O43290 T430 Sugiyama SART1 RKKEKEVVVRADDLLPLGDQtQDGDFGsRLRGRGRRRVsEV
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43390 T141 Sugiyama HNRNPR HNRPR GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP
O43399 T146 Sugiyama TPD52L2 yKKTQETLsQAGQKtsAALstVGsAIsRKLGDMRNsAtFKs
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43707 T69 Sugiyama ACTN4 EKQQRKTFTAWCNsHLRKAGtQIENIDEDFRDGLKLMLLLE
O43852 T196 Sugiyama CALU FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60231 T110 Sugiyama DHX16 DBP2 DDX16 KIAA0577 PRP2 LLEKNRSYRLLEDsEEssEEtVsRAGsSLQKKRKKRKHLRK
O60361 S107 Sugiyama NME2P1 GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDY
O60361 T88 Sugiyama NME2P1 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O60506 T138 Sugiyama SYNCRIP HNRPQ NSAP1 GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP
O60716 S230 Sugiyama CTNND1 KIAA0384 PDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRA
O60716 S232 Sugiyama CTNND1 KIAA0384 GysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRAPs
O60814 S39 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
O60927 T75 Sugiyama PPP1R11 HCGV TCTE5 RRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHR
O75347 S103 Sugiyama TBCA ENEKDLEEAEEyKEARLVLDsVKLEA_______________
O75369 T907 Sugiyama FLNB FLN1L FLN3 TABP TAP PLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLVTYGGD
O75390 T335 Sugiyama CS LQKEVGKDVSDEKLRDYIWNtLNSGRVVPGyGHAVLRKTDP
O75534 T761 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR GPKAVAAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDN
O75821 S217 Sugiyama EIF3G EIF3S4 PGELEPVQAtQNKtGKYVPPsLRDGAsRRGESMQPNRRADD
O75821 T240 Sugiyama EIF3G EIF3S4 DGAsRRGESMQPNRRADDNAtIRVtNLSEDTRETDLQELFR
O75822 T33 Sugiyama EIF3J EIF3S1 PRO0391 sWDADAFsVEDPVRKVGGGGtAGGDRWEGEDEDEDVKDNWD
O95071 T119 Sugiyama UBR5 EDD EDD1 HYD KIAA0896 GRTSRPGRTSDsPWFLsGSEtLGRLAGNTLGSRWSsGVGGs
O95255 S66 Sugiyama ABCC6 ARA MRP6 VLGPIYLLFIHHHGRGYLRMsPLFKAKMVLGFALIVLCTSS
O95678 S162 Sugiyama KRT75 K6HF KB18 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
O95707 T62 Sugiyama POP4 RPP29 MsPQAREDQLQRKAVVLEyFtRHKRKEKKKKAKGLSARQRR
O95714 S2928 Sugiyama HERC2 ILLGRIRAEEEDLAAVPFLAsDNEEEEDEKGNSGsLIRKKA
O95757 S587 Sugiyama HSPA4L APG1 HSPH3 OSP94 RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00338 T322 Sugiyama LDHA PIG19 DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________
P00390 T507 Sugiyama GSR GLUR GRD1 MLQGFAVAVKMGATKADFDNtVAIHPtssEELVtLR_____
P00390 T520 Sugiyama GSR GLUR GRD1 TKADFDNtVAIHPtssEELVtLR__________________
P00492 S123 Sugiyama HPRT1 HPRT KsYCNDQsTGDIKVIGGDDLstLTGKNVLIVEDIIDTGKTM
P00492 T124 Sugiyama HPRT1 HPRT sYCNDQsTGDIKVIGGDDLstLTGKNVLIVEDIIDTGKTMQ
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P02538 S176 Sugiyama KRT6A K6A KRT6D IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT
P02786 T143 Sugiyama TFRC yWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAGsQKDE
P02786 T336 Sugiyama TFRC FNHTQFPPSRSSGLPNIPVQtISRAAAEKLFGNMEGDCPSD
P04040 S517 Sugiyama CAT LDKYNAEKPKNAIHtFVQsGsHLAAREKANL__________
P04040 T125 Sugiyama CAT KKTPIAVRFStVAGEsGSADtVRDPRGFAVKFYTEDGNWDL
P04040 T434 Sugiyama CAT QQPSALEHSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEE
P04040 T511 Sugiyama CAT SHIQALLDKYNAEKPKNAIHtFVQsGsHLAAREKANL____
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T119 Sugiyama ALDOA ALDA KsKGGVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYK
P04083 S173 Sugiyama ANXA1 ANX1 LPC1 NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG
P04083 T223 Sugiyama ANXA1 ANX1 LPC1 ARALyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKY
P04083 T226 Sugiyama ANXA1 ANX1 LPC1 LyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKYSKH
P04083 T64 Sugiyama ANXA1 ANX1 LPC1 PssDVAALHKAIMVKGVDEAtIIDILtKRNNAQRQQIKAAY
P04083 T70 Sugiyama ANXA1 ANX1 LPC1 ALHKAIMVKGVDEAtIIDILtKRNNAQRQQIKAAYLQEtGK
P04259 S176 Sugiyama KRT6B K6B KRTL1 IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P04406 S321 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______
P04406 T211 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P04632 T143 Sugiyama CAPNS1 CAPN4 CAPNS ILNKVVTRHPDLKTDGFGIDtCRSMVAVMDSDTTGKLGFEE
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05787 S104 Sugiyama KRT8 CYK8 IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS
P05787 S410 Sugiyama KRT8 CYK8 TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P06703 S46 Sugiyama S100A6 CACY KHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRNKDQ
P06703 T43 Sugiyama S100A6 CACY EGDKHTLSKKELKELIQKELtIGsKLQDAEIARLMEDLDRN
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 S37 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 T55 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP
P06748 S125 Sugiyama NPM1 NPM GsGPVHIsGQHLVAVEEDAEsEDEEEEDVKLLsIsGKRsAP
P06748 S260 Sugiyama NPM1 NPM GPssVEDIKAKMQAsIEKGGsLPKVEAKFINyVKNCFRMtD
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07195 T302 Sugiyama LDHB YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07437 S75 Sugiyama TUBB TUBB5 OK/SW-cl.56 tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
P07686 T474 Sugiyama HEXB HCC7 ISYGQDWRKyyKVEPLDFGGtQKQKQLFIGGEACLWGEYVD
P07737 T65 Sugiyama PFN1 PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 T1506 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 LCELQPGAKCVCGKNPAKyytLFGRsy______________
P07858 T95 Sugiyama CTSB CPSB TEDLKLPAsFDAREQWPQCPtIKEIRDQGSCGSCWAFGAVE
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S165 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK
P07900 S476 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S641 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD
P07900 T109 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LtIVDtGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
P07900 T317 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA WtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P07900 T624 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE
P07900 T645 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL
P08195 S292 Sugiyama SLC3A2 MDU1 VAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNY
P08195 T321 Sugiyama SLC3A2 MDU1 SIRVILDLTPNYRGENSWFStQVDtVATKVKDALEFWLQAG
P08195 T325 Sugiyama SLC3A2 MDU1 ILDLTPNYRGENSWFStQVDtVATKVKDALEFWLQAGVDGF
P08238 S160 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 T104 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LtLVDtGIGMtKADLINNLGtIAKSGtKAFMEALQAGADIS
P08238 T309 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB WtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEGQLEF
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08238 T637 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL
P08238 T85 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LDsGKELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtI
P08238 T89 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KELKIDIIPNPQERtLtLVDtGIGMtKADLINNLGtIAKSG
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08708 T22 Sugiyama RPS17 RPS17L GRVRTKTVKKAARVIIEKyytRLGNDFHtNKRVCEEIAIIP
P08729 S104 Sugiyama KRT7 SCL LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT
P08758 T40 Sugiyama ANXA5 ANX5 ENX2 PP4 DAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTL
P08758 T43 Sugiyama ANXA5 ANX5 ENX2 PP4 tLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTLFGR
P08758 T8 Sugiyama ANXA5 ANX5 ENX2 PP4 _____________MAQVLRGtVtDFPGFDERADAEtLRKAM
P09104 S37 Sugiyama ENO2 NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY
P09211 T62 Sugiyama GSTP1 FAEES3 GST3 GsLKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGK
P09211 T68 Sugiyama GSTP1 FAEES3 GST3 CLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQEAA
P09211 Y64 Sugiyama GSTP1 FAEES3 GST3 LKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQ
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09429 S15 Sugiyama HMGB1 HMG1 ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAs
P09429 T22 Sugiyama HMGB1 HMG1 GKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAsVNFsEFs
P09651 S368 Sugiyama HNRNPA1 HNRPA1 FAKPRNQGGyGGssssssyGsGRRF________________
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10646 S237 Sugiyama TFPI LACI TFPI1 CLTPADRGLCRANENRFyyNsVIGKCRPFKYSGCGGNENNF
P10646 Y235 Sugiyama TFPI LACI TFPI1 SWCLTPADRGLCRANENRFyyNsVIGKCRPFKYSGCGGNEN
P10809 T231 Sugiyama HSPD1 HSP60 LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T425 Sugiyama HSPA8 HSC70 HSP73 HSPA10 TAGGVMTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEG
P11142 T427 Sugiyama HSPA8 HSC70 HSP73 HSPA10 GGVMTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGER
P11142 T47 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11586 T527 Sugiyama MTHFD1 MTHFC MTHFD PTTLtDEEINRFARLDIDPEtITWQRVLDTNDRFLRKITIG
P11940 T379 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 AtKPLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINP
P12035 S211 Sugiyama KRT3 IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN
P12268 S416 Sugiyama IMPDH2 IMPD2 APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12814 T424 Sugiyama ACTN1 sIHEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEsDL
P12814 T426 Sugiyama ACTN1 HEAWtDGKEAMLRQKDyEtAtLsEIKALLKKHEAFEsDLAA
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 T34 Sugiyama EEF2 EF2 DKKANIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEt
P13639 T5 Sugiyama EEF2 EF2 ________________MVNFtVDQIRAIMDKKANIRNMsVI
P13639 T735 Sugiyama EEF2 EF2 HRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCPEQV
P13647 S181 Sugiyama KRT5 IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13667 T139 Sugiyama PDIA4 ERP70 ERP72 KIDAtsAsVLAsRFDVsGyPtIKILKKGQAVDyEGsRtQEE
P13674 T140 Sugiyama P4HA1 P4HA YFPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKS
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13929 S37 Sugiyama ENO3 NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY
P13987 T76 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P15153 T161 Sugiyama RAC2 QGLALAKEIDSVKyLECsALtQRGLKtVFDEAIRAVLCPQP
P15170 T315 Sugiyama GSPT1 ERF3A NRSVDGPIRLPIVDKYKDMGtVVLGKLESGSICKGQQLVMM
P15311 T567 SIGNOR|EPSD|PSP EZR VIL2 RTHNDIIHNENMRQGRDKYKtLRQIRQGNTKQRIDEFEAL_
P15531 S122 Sugiyama NME1 NDPKA NM23 GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy
P15531 T103 Sugiyama NME1 NDPKA NM23 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P15880 T230 Sugiyama RPS2 RPS4 PKKLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysy
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P15880 T285 Sugiyama RPS2 RPS4 PyQEFtDHLVKtHtRVsVQRtQAPAVATt____________
P15924 T61 Sugiyama DSP YYSRRGVITDQNsDGyCQtGtMsRHQNQNTIQELLQNCSDC
P16070 T76 Sugiyama CD44 LHR MDU2 MDU3 MIC4 FNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRIHPNSI
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17066 T49 Sugiyama HSPA6 HSP70B' EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P17844 T438 Sugiyama DDX5 G17P1 HELR HLR1 yPNSsEDyIHRIGRTARSTKtGtAytFFtPNNIKQVSDLIS
P17844 T443 Sugiyama DDX5 G17P1 HELR HLR1 EDyIHRIGRTARSTKtGtAytFFtPNNIKQVSDLISVLREA
P17987 S35 Sugiyama TCP1 CCT1 CCTA EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT
P18124 T17 Sugiyama RPL7 ____MEGVEEKKKEVPAVPEtLKKKRRNFAELKIKRLRKKF
P18124 T170 Sugiyama RPL7 VNELIyKRGYGKINKKRIALtDNALIARSLGKyGIICMEDL
P18621 T79 Sugiyama RPL17 PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE
P18669 S152 Sugiyama PGAM1 PGAMA CDABP0006 FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 T146 Sugiyama PGAM1 PGAMA CDABP0006 MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P19105 T159 Sugiyama MYL12A MLCB MRLC3 RLC DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P19338 S595 Sugiyama NCL FVKGLsEDttEEtLKEsFDGsVRARIVTDRETGssKGFGFV
P19338 T452 Sugiyama NCL AyIEFKTEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQD
P19338 T464 Sugiyama NCL KTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsGE
P19338 T587 Sugiyama NCL RSQPSKTLFVKGLsEDttEEtLKEsFDGsVRARIVTDRETG
P19338 Y463 Sugiyama NCL EKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsG
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20674 T105 Sugiyama COX5A EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY
P22090 S204 Sugiyama RPS4Y1 RPS4Y PRO2646 IGGANLGRVGVITNRERHPGsFDVVHVKDANGNSFATRLSN
P22392 S122 Sugiyama NME2 NM23B GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDy
P22392 T103 Sugiyama NME2 NM23B VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P22626 T140 Sugiyama HNRNPA2B1 HNRPA2B1 KEDTEEHHLRDyFEEYGKIDtIEIItDRQsGKKRGFGFVtF
P23193 T256 Sugiyama TCEA1 GTF2S TFIIS MRKNLTKEAIREHQMAKTGGtQTDLFtCGKCKKKNCTYTQV
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23381 S358 Sugiyama WARS1 IFI53 WARS WRS TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs
P23381 T364 Sugiyama WARS1 IFI53 WARS WRS QGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRDtI
P23381 T383 Sugiyama WARS1 IFI53 WARS WRS DtAKQIKTKVNKHAFsGGRDtIEEHRQFGGNCDVDVSFMYL
P23396 S104 Sugiyama RPS3 OK/SW-cl.26 VELyAEKVAtRGLCAIAQAEsLRyKLLGGLAVRRACyGVLR
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23528 T91 Sugiyama CFL1 CFL FVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPESAPL
P23528 Y89 Sugiyama CFL1 CFL AtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPESA
P24752 S218 Sugiyama ACAT1 ACAT MAT ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV
P24752 T220 Sugiyama ACAT1 ACAT MAT TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV
P24941 T160 Sugiyama CDK2 CDKN2 AIKLADFGLARAFGVPVRtytHEVVtLWyRAPEILLGCKYY
P25705 S198 Sugiyama ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK
P25786 T11 Sugiyama PSMA1 HC2 NU PROS30 PSC2 __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ
P25789 T9 Sugiyama PSMA4 HC9 PSC9 ____________MSRRyDsRttIFsPEGRLYQVEYAMEAIG
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26373 T24 Sugiyama RPL13 BBC1 OK/SW-cl.46 SRNGMVLKPHFHKDWQRRVAtWFNQPARKIRRRKARQAKAR
P26583 S15 Sugiyama HMGB2 HMG2 ______MGKGDPNKPRGKMssyAFFVQtCREEHKKKHPDss
P26583 T22 Sugiyama HMGB2 HMG2 GKGDPNKPRGKMssyAFFVQtCREEHKKKHPDssVNFAEFS
P26639 T700 Sugiyama TARS1 TARS EKISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAE
P26641 T287 Sugiyama EEF1G EF1G PRO1608 EQALAAEPKAKDPFAHLPKstFVLDEFKRKysNEDtLsVAL
P27348 S45 Sugiyama YWHAQ CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI
P27348 T205 Sugiyama YWHAQ PELACTLAKTAFDEAIAELDtLNEDsyKDstLIMQLLRDNL
P27695 S66 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 EDPPDQKtsPsGKPAtLKICsWNVDGLRAWIKKKGLDWVKE
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P28340 S1064 Sugiyama POLD1 POLD LNALEERFSRLWTQCQRCQGsLHEDVICTSRDCPIFyMRKK
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29401 T454 Sugiyama TKT LAMFRsVPtstVFyPsDGVAtEKAVELAANTKGICFIRTsR
P29692 S162 Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 S60 Sugiyama EEF1D EF1D ENGAsVILRDIARARENIQKsLAGssGPGAssGtsGDHGEL
P30041 T48 Sugiyama PRDX6 AOP2 KIAA0106 FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL
P30041 T49 Sugiyama PRDX6 AOP2 KIAA0106 LGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKLI
P30043 T199 Sugiyama BLVRB FLR SCAN HDLGHFMLRCLttDEyDGHstyPsHQyQ_____________
P30050 T135 Sugiyama RPL12 QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30086 S60 Sugiyama PEBP1 PBP PEBP VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK
P30086 S99 Sugiyama PEBP1 PBP PEBP PKYREWHHFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHR
P30086 T167 Sugiyama PEBP1 PBP PEBP GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30086 Y64 Sugiyama PEBP1 PBP PEBP tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW
P30101 T102 Sugiyama PDIA3 ERP57 ERP60 GRP58 KVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRtAD
P30626 T130 Sugiyama SRI IsFDTDRSGTVDPQELQKALttMGFRLsPQAVNSIAKRYst
P30626 T131 Sugiyama SRI sFDTDRSGTVDPQELQKALttMGFRLsPQAVNSIAKRYstN
P31942 S298 Sugiyama HNRNPH3 HNRPH3 GGsGMGGYGRDGMDNQGGyGsVGRMGMGNNysGGyGtPDGL
P31946 S47 Sugiyama YWHAB AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI
P31947 S45 Sugiyama SFN HME1 FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI
P31948 T243 Sugiyama STIP1 KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT
P31949 T33 Sugiyama S100A11 MLN70 S100C CIESLIAVFQKYAGKDGyNytLsKtEFLsFMNTELAAFTKN
P32119 T142 Sugiyama PRDX2 NKEFB TDPX1 EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF
P32929 T372 Sugiyama CTH AIMtHASVLKNDRDVLGISDtLIRLsVGLEDEEDLLEDLDQ
P33121 T695 Sugiyama ACSL1 FACL1 FACL2 LACS LACS1 LACS2 KAKRPELRNYFRSQIDDLyStIKV_________________
P33991 T854 Sugiyama MCM4 CDC21 AITKDMFEEALRALADDDFLtVtGKtVRLL___________
P33991 T859 Sugiyama MCM4 CDC21 MFEEALRALADDDFLtVtGKtVRLL________________
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931 T49 Sugiyama HSPA1L EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV
P35269 T154 Sugiyama GTF2F1 RAP74 AFEAFPVHNWYNFTPLARHRtLtAEEAEEEWERRNKVLNHF
P35269 T41 Sugiyama GTF2F1 RAP74 NTTKKyNIMAFNAADKVNFAtWNQARLERDLSNKKIyQEEE
P35579 S1892 Sugiyama MYH9 LKQLKRQLEEAEEEAQRANAsRRKLQRELEDAtEtADAMNR
P35579 T1151 Sugiyama MYH9 EKQKRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNI
P35579 T1208 Sugiyama MYH9 QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE
P35658 T860 Sugiyama NUP214 CAIN CAN KIAA0023 LEQKKKQRHLLVPERETLFNtLANNREIINQQRKRLNHLVD
P35908 S191 Sugiyama KRT2 KRT2A KRT2E IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE
P36578 S66 Sugiyama RPL4 RPL1 KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578 T69 Sugiyama RPL4 RPL1 RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P36871 S483 Sugiyama PGM1 DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37108 T29 Sugiyama SRP14 FLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGtVEGF
P37108 T45 Sugiyama SRP14 sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37108 Y27 Sugiyama SRP14 EQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGtVE
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P38117 T172 Sugiyama ETFB FP585 QVTLEGDKLKVEREIDGGLEtLRLKLPAVVTADLRLNEPRy
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 T94 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 S59 Sugiyama RPS19 LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019 S93 Sugiyama RPS19 GsMTKIYGGRQRNGVMPsHFsRGsKsVARRVLQALEGLKMV
P39019 T55 Sugiyama RPS19 DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM
P39019 T60 Sugiyama RPS19 AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P41091 T22 Sugiyama EIF2S3 EIF2G AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
P41091 T41 Sugiyama EIF2S3 EIF2G ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
P41091 T430 Sugiyama EIF2S3 EIF2G sLstGGRVSAVKADLGKIVLtNPVCtEVGEKIALSRRVEKH
P41091 T435 Sugiyama EIF2S3 EIF2G GRVSAVKADLGKIVLtNPVCtEVGEKIALSRRVEKHWRLIG
P41091 T46 Sugiyama EIF2S3 EIF2G tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHt
P41091 T9 Sugiyama EIF2S3 EIF2G ____________MAGGEAGVtLGQPHLsRQDLttLDVtKLT
P42677 S11 Sugiyama RPS27 MPS1 __________MPLAKDLLHPsPEEEKRKHKKKRLVQsPNsy
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42766 T59 Sugiyama RPL35 GAASKLsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyK
P42766 T64 Sugiyama RPL35 LsKIRVVRKSIARVLtVINQtQKENLRKFYKGKKyKPLDLR
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P46060 T247 Sugiyama RANGAP1 KIAA1835 SD ALAQAFAVNPLLRVINLNDNtFTEKGAVAMAETLKTLRQVE
P46108 S41 Sugiyama CRK QEAVALLQGQRHGVFLVRDsstsPGDyVLSVSENSRVSHYI
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S230 Sugiyama RPL5 MSTP030 yLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAHAAIREN
P46777 T177 Sugiyama RPL5 MSTP030 NKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRK
P46778 T29 Sugiyama RPL21 RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ
P46779 T80 Sugiyama RPL28 VVVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKN
P46779 T81 Sugiyama RPL28 VVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKNK
P46781 S160 Sugiyama RPS9 QVVNIPSFIVRLDsQKHIDFsLRsPYGGGRPGRVKRKNAKK
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46937 S94 PSP YAP1 YAP65 NPKtANVPQtVPMRLRKLPDsFFKPPEPKsHsRQAstDAGt
P46937 T110 PSP YAP1 YAP65 KLPDsFFKPPEPKsHsRQAstDAGtAGALtPQHVRAHssPA
P46937 T41 PSP YAP1 YAP65 SQPPQGQGPPSGPGQPAPAAtQAAPQAPPAGHQIVHVRGDs
P46937 T77 PSP YAP1 YAP65 VRGDsEtDLEALFNAVMNPKtANVPQtVPMRLRKLPDsFFK
P46937 T83 PSP YAP1 YAP65 tDLEALFNAVMNPKtANVPQtVPMRLRKLPDsFFKPPEPKs
P47756 T186 Sugiyama CAPZB HYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDC
P48643 T47 Sugiyama CCT5 CCTE KIAA0098 RLMGLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGD
P48643 T50 Sugiyama CCT5 CCTE KIAA0098 GLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtV
P48668 S176 Sugiyama KRT6C KRT6E IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P48741 T49 Sugiyama HSPA7 HSP70B EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P49368 T459 Sugiyama CCT3 CCTG TRIC5 AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG
P49368 T484 Sugiyama CCT3 CCTG TRIC5 tSLRAKHtQENCEtWGVNGEtGtLVDMKELGIWEPLAVKLQ
P49411 T433 Sugiyama TUFM LRQPMILEKGQRFTLRDGNRtIGTGLVTNTLAMTEEEKNIK
P49589 S34 Sugiyama CARS1 CARS VQPQWsPPAGtQPCRLHLyNsLtRNKEVFIPQDGKKVTWYC
P49590 S127 Sugiyama HARS2 HARSL HARSR HO3 KYGEDSGLMYDLKDQGGELLsLRYDLTVPFARYLAMNKVKK
P49773 T17 Sugiyama HINT1 HINT PKCI1 PRKCNH1 ____MADEIAKAQVARPGGDtIFGKIIRKEIPAKIIFEDDR
P49840 Y279 Sugiyama GSK3A LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841 Y216 Sugiyama GSK3B LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P50402 T43 Sugiyama EMD EDMD STA HGPVVGstRRLyEKKIFEyEtQRRRLsPPsssAAssysFsD
P50613 S164 Sugiyama CDK7 CAK CAK1 CDKN7 MO15 STK1 LLDENGVLKLADFGLAKsFGsPNRAytHQVVtRWYRAPELL
P50613 T170 Sugiyama CDK7 CAK CAK1 CDKN7 MO15 STK1 VLKLADFGLAKsFGsPNRAytHQVVtRWYRAPELLFGARMY
P50613 Y169 Sugiyama CDK7 CAK CAK1 CDKN7 MO15 STK1 GVLKLADFGLAKsFGsPNRAytHQVVtRWYRAPELLFGARM
P50990 T374 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDD
P50990 T398 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 RGstDNLMDDIERAVDDGVNtFKVLTRDKRLVPGGGAtEIE
P50991 S51 Sugiyama CCT4 CCTD SRB AQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtIt
P50991 T50 Sugiyama CCT4 CCTD SRB PAQIRFsNISAAKAVADAIRtsLGPKGMDKMIQDGKGDVtI
P50991 T69 Sugiyama CCT4 CCTD SRB RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR
P51116 S601 Sugiyama FXR2 FMR1L2 RPQRRNRSRRRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQ
P51116 T610 Sugiyama FXR2 FMR1L2 RRRNRGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLER
P51149 T168 Sugiyama RAB7A RAB7 NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE
P51532 S1382 Sugiyama SMARCA4 BAF190A BRG1 SNF2B SNF2L4 EEEKMFGRGSRHRKEVDYsDsLTEKQWLKAIEEGtLEEIEE
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P52272 T68 Sugiyama HNRNPM HNRPM NAGR1 KRKEKNIKRGGNRFEPyANPtKRYRAFITNIPFDVKWQsLK
P52948 S872 Sugiyama NUP98 ADAR2 LEAVSRKQGAQFKEyRPEtGsWVFKVSHFSKYGLQDsDEEE
P53621 T821 Sugiyama COPA IMPLDTNWPLLTVSKGFFEGtIAsKGKGGALAADIDIDTVG
P53634 T431 Sugiyama CTSC CPPI GYGTDSASGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIE
P54652 T164 Sugiyama HSPA2 VITVPAYFNDSQRQATKDAGtITGLNVLRIINEPtAAAIAy
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T48 Sugiyama HSPA2 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI
P55036 S358 Sugiyama PSMD4 MCB1 VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55854 S27 Sugiyama SUMO3 SMT3A SMT3H1 KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P56192 S812 Sugiyama MARS1 MARS GHQIGTVSPLFQKLENDQIEsLRQRFGGGQAKtsPKPAVVE
P56537 T91 Sugiyama EIF6 EIF3A ITGB4BP OK/SW-cl.27 LVPNNTTDQELQHIRNSLPDtVQIRRVEERLSALGNVTTCN
P57053 S39 Sugiyama H2BC12L H2BFS H2BS1 VTKAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P58876 S39 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
P60174 S204 Sugiyama TPI1 TPI EVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQ
P60174 S21 Sugiyama TPI1 TPI MAPSRKFFVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVV
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 T205 Sugiyama TPI1 TPI VHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQP
P60174 T214 Sugiyama TPI1 TPI KsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGG
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T28 Sugiyama TPI1 TPI FVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVVCAPPtAy
P60174 T38 Sugiyama TPI1 TPI RKQsLGELIGtLNAAKVPADtEVVCAPPtAyIDFARQKLDP
P60174 T46 Sugiyama TPI1 TPI IGtLNAAKVPADtEVVCAPPtAyIDFARQKLDPKIAVAAQN
P60174 T90 Sugiyama TPI1 TPI VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 T85 Sugiyama MYL6 LDFEHFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVM
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S300 Sugiyama ACTB NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 S52 Sugiyama ACTB PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P60709 S60 Sugiyama ACTB HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T202 Sugiyama ACTB GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709 T297 Sugiyama ACTB TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709 T303 Sugiyama ACTB MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P60709 T304 Sugiyama ACTB KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y53 Sugiyama ACTB sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P60763 T161 Sugiyama RAC3 QGLAMAREIGSVKyLECsALtQRGLKtVFDEAIRAVLCPPP
P60842 T80 Sugiyama EIF4A1 DDX2A EIF4A QRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDLKA
P61221 S186 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 AIIKPQYVDQIPKAAKGtVGsILDRKDETKTQAIVCQQLDL
P61221 T183 Sugiyama ABCE1 RLI RNASEL1 RNASELI RNS4I OK/SW-cl.40 DLKAIIKPQYVDQIPKAAKGtVGsILDRKDETKTQAIVCQQ
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61254 T93 Sugiyama RPL26 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
P61254 T94 Sugiyama RPL26 YRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDKD
P61289 T99 Sugiyama PSME3 LDGPTYKKRRLDECEEAFQGtKVFVMPNGMLKSNQQLVDII
P61604 S64 Sugiyama HSPE1 AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD
P61604 T45 Sugiyama HSPE1 TVTKGGIMLPEKSQGKVLQAtVVAVGsGsKGKGGEIQPVsV
P61604 T79 Sugiyama HSPE1 EIQPVsVKVGDKVLLPEyGGtKVVLDDKDyFLFRDGDILGK
P61956 S28 Sugiyama SUMO2 SMT3B SMT3H2 EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 S420 Sugiyama HNRNPK HNRPK GsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITItGt
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61981 S46 Sugiyama YWHAG AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI
P61981 T210 Sugiyama YWHAG PEQACHLAKtAFDDAIAELDtLNEDsyKDstLIMQLLRDNL
P62081 T172 Sugiyama RPS7 RLIKVHLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEF
P62241 S115 Sugiyama RPS8 OK/SW-cl.83 TLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEE
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S46 Sugiyama YWHAE SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62263 T140 Sugiyama RPS14 PRO2640 ARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL_________
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62266 T34 Sugiyama RPS23 RSHRRDQKWHDKQYKKAHLGtALKANPFGGAsHAKGIVLEK
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62273 S9 Sugiyama RPS29 ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T15 Sugiyama RPS11 ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62280 T28 Sugiyama RPS11 RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62312 T75 Sugiyama LSM6 QLKNKyGDAFIRGNNVLyIstQKRRM_______________
P62316 T40 Sugiyama SNRPD2 SNRPD1 EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD
P62424 T142 Sugiyama RPL7A SURF-3 SURF3 AAGKGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVD
P62424 T145 Sugiyama RPL7A SURF-3 SURF3 KGDVPTKRPPVLRAGVNtVttLVENKKAQLVVIAHDVDPIE
P62424 T84 Sugiyama RPL7A SURF-3 SURF3 QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP
P62701 S204 Sugiyama RPS4X CCG2 RPS4 SCAR tGGANLGRIGVITNRERHPGsFDVVHVKDANGNSFATRLsN
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 S54 Sugiyama ACTA2 ACTSA ACTVS GIG46 PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P62736 S62 Sugiyama ACTA2 ACTSA ACTVS GIG46 HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y55 Sugiyama ACTA2 ACTSA ACTVS GIG46 sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62750 T42 Sugiyama RPL23A LKAKKAVLKGVHSHKKKKIRtsPTFRRPKTLRLRRQPKYPR
P62753 T125 Sugiyama RPS6 OK/SW-cl.2 NLSVLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLF
P62753 T127 Sugiyama RPS6 OK/SW-cl.2 SVLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNL
P62753 T128 Sugiyama RPS6 OK/SW-cl.2 VLNLVIVKKGEKDIPGLtDttVPRRLGPKRASRIRKLFNLs
P62807 S39 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI VTKAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKA
P62826 T21 Sugiyama RAN ARA24 OK/SW-cl.81 MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62826 T66 Sugiyama RAN ARA24 OK/SW-cl.81 EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA
P62857 T57 Sugiyama RPS28 DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________
P62888 T83 Sugiyama RPL30 yAMLAKtGVHHysGNNIELGtACGKyyRVCtLAIIDPGDsD
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62899 Y108 Sugiyama RPL31 LSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN___
P62899 Y25 Sugiyama RPL31 KKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRA
P62906 S64 Sugiyama RPL10A NEDD6 QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62913 S59 Sugiyama RPL11 VLEQLtGQtPVFsKARyTVRsFGIRRNEKIAVHCTVRGAKA
P62913 Y55 Sugiyama RPL11 RAAKVLEQLtGQtPVFsKARyTVRsFGIRRNEKIAVHCTVR
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 T143 Sugiyama RPL8 RGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANR
P62917 T146 Sugiyama RPL8 LARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANRAVV
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 S51 Sugiyama PPIA CYPA KtAENFRALSTGEKGFGYKGsCFHRIIPGFMCQGGDFtRHN
P62937 T157 Sugiyama PPIA CYPA NIVEAMERFGsRNGKTSKKItIADCGQLE____________
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62979 S134 Sugiyama RPS27A UBA80 UBCEP1 IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE
P63000 T161 Sugiyama RAC1 TC25 MIG5 QGLAMAKEIGAVKyLECsALtQRGLKtVFDEAIRAVLCPPP
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63104 S45 Sugiyama YWHAZ CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI
P63151 S409 Sugiyama PPP2R2A RTVLKPRKVCASGKRKKDEIsVDsLDFNKKILHTAWHPKEN
P63151 S412 Sugiyama PPP2R2A LKPRKVCASGKRKKDEIsVDsLDFNKKILHTAWHPKENIIA
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S300 Sugiyama ACTG1 ACTG NSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItAL
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 S52 Sugiyama ACTG1 ACTG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE
P63261 S60 Sugiyama ACTG1 ACTG HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T202 Sugiyama ACTG1 ACTG GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261 T297 Sugiyama ACTG1 ACTG TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261 T303 Sugiyama ACTG1 ACTG MKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPs
P63261 T304 Sugiyama ACTG1 ACTG KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y53 Sugiyama ACTG1 ACTG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 S53 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P63267 S61 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y54 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 S54 Sugiyama ACTC1 ACTC PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68032 S62 Sugiyama ACTC1 ACTC HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y55 Sugiyama ACTC1 ACTC sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68104 T22 Sugiyama EEF1A1 EEF1A EF1A LENG7 GKEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKF
P68104 T261 Sugiyama EEF1A1 EEF1A EF1A LENG7 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 S54 Sugiyama ACTA1 ACTA PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE
P68133 S62 Sugiyama ACTA1 ACTA HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y55 Sugiyama ACTA1 ACTA sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH
P68363 T73 Sugiyama TUBA1B FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68363 Y83 Sugiyama TUBA1B PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
P78371 S60 Sugiyama CCT2 99D8.1 CCTB KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA
P78371 T69 Sugiyama CCT2 99D8.1 CCTB DKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVLVDMSR
P78417 S23 Sugiyama GSTO1 GSTTLP28 GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK
P78417 Y27 Sugiyama GSTO1 GSTTLP28 RsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLKAKGI
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 S7 Sugiyama RPL24 ______________MKVELCsFsGyKIYPGHGRRYARTDGK
P83731 T52 Sugiyama RPL24 LNAKCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRT
P83731 Y55 Sugiyama RPL24 KCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRTRRA
P84098 S122 Sugiyama RPL19 LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI
P84098 S13 Sugiyama RPL19 ________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEIA
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84103 S95 Sugiyama SRSF3 SFRS3 SRP20 RVRVELSNGEKRSRNRGPPPsWGRRPRDDYRRRSPPPRRRS
P99999 T50 Sugiyama CYCS CYC GPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEYLE
Q00341 T729 Sugiyama HDLBP HBP VGL VEKAKKQLLHLAEEKQTKSFtVDIRAKPEYHKFLIGKGGGK
Q00526 T160 Sugiyama CDK3 CDKN3 AIKLADFGLARAFGVPLRtYtHEVVTLWYRAPEILLGSKFY
Q00839 S267 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KRPREDHGRGyFEyIEENKysRAKsPQPPVEEEDEHFDDtV
Q00839 T530 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KTTWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtG
Q00839 T532 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 TWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtGKL
Q01082 S1388 Sugiyama SPTBN1 SPTB2 TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy
Q01105 S165 Sugiyama SET PyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQ
Q01518 T165 Sugiyama CAP1 CAP AMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVKA
Q01546 S196 Sugiyama KRT76 KRT2B KRT2P IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02543 Y97 Sugiyama RPL18A NFGIWLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARH
Q02790 T278 Sugiyama FKBP4 FKBP52 sWEMNsEEKLEQSTIVKERGtVYFKEGKYKQALLQYKKIVS
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q04760 T35 Sugiyama GLO1 AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM
Q04917 S46 Sugiyama YWHAH YWHA1 AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI
Q05639 T22 Sugiyama EEF1A2 EEF1AL STN GKEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKF
Q05639 T261 Sugiyama EEF1A2 EEF1AL STN PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06830 T143 Sugiyama PRDX1 PAGA PAGB TDPX2 EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020 T39 Sugiyama RPL18 KSQDIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRP
Q07020 T42 Sugiyama RPL18 DIyLRLLVKLYRFLARRtNstFNQVVLKRLFMSRtNRPPLs
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q07157 T1167 Sugiyama TJP1 ZO1 EQAPRAsALRHEEQPAPGyDtHGRLRPEAQPHPsAGPKPAE
Q13131 T183 PSP PRKAA1 AMPK1 NAKIADFGLsNMMsDGEFLRtsCGsPNyAAPEVISGRLYAG
Q13136 T572 Sugiyama PPFIA1 LIP1 LRRPQKGRLAALRDEPSKVQtLNEQDWERAQQASVLANVAQ
Q13263 S784 Sugiyama TRIM28 KAP1 RNF96 TIF1B DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK
Q13283 T241 Sugiyama G3BP1 G3BP ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP
Q13409 S111 Sugiyama DYNC1I2 DNCI2 DNCIC2 KsVStPsEAGsQDsGDGAVGsRTLHWDTDPSVLQLHSDSDL
Q13509 S75 Sugiyama TUBB3 TUBB4 SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS
Q13561 T315 Sugiyama DCTN2 DCTN50 KHKASVEDADTQSKVHQLyEtIQRWsPIASTLPELVQRLVT
Q13765 T119 Sugiyama NACA HSD48 SKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAA
Q13885 S75 Sugiyama TUBB2A TUBB2 AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q14004 S389 Sugiyama CDK13 CDC2L CDC2L5 CHED KIAA1791 SYSRHSSYERGGDVsPsPyssSsWRRsRsPysPVLRRSGKS
Q14103 S271 Sugiyama HNRNPD AUF1 HNRPD KCEIKVAMSKEQyQQQQQWGsRGGFAGRARGRGGGPSQNWN
Q14103 T127 Sugiyama HNRNPD AUF1 HNRPD DTTKKDLKDYFSKFGEVVDCtLKLDPITGRSRGFGFVLFKE
Q14152 S1028 Sugiyama EIF3A EIF3S10 KIAA0139 NWRHADDDRPPRRGLDEDRGsWRtADEDRGPRRGMDDDRGP
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14152 S988 Sugiyama EIF3A EIF3S10 KIAA0139 PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN
Q14152 T1378 Sugiyama EIF3A EIF3S10 KIAA0139 AEKDREsLRRTKNEtDEDGWttVRR________________
Q14152 T1379 Sugiyama EIF3A EIF3S10 KIAA0139 EKDREsLRRTKNEtDEDGWttVRR_________________
Q14152 T898 Sugiyama EIF3A EIF3S10 KIAA0139 LGDssLSRKDSRWGDRDsEGtWRKGPEADsEWRRGPPEKEW
Q14157 S852 Sugiyama UBAP2L KIAA0144 NICE4 LDyysIPFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASS
Q14157 T358 Sugiyama UBAP2L KIAA0144 NICE4 MVsMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLAAQ
Q14240 T81 Sugiyama EIF4A2 DDX2B EIF4F QRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEFKE
Q14247 S113 Sugiyama CTTN EMS1 DRMDKsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVD
Q14568 S165 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK
Q14568 T109 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LTIVDTGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
Q14677 T271 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 KDEEETVTTKHIHItQATEttttRHKRTANPsKtIDLGAAA
Q14697 S44 Sugiyama GANAB G2AN KIAA0088 GVCLGITLAVDRSNFKtCEEssFCKRQRsIRPGLsPyRALL
Q14697 T40 Sugiyama GANAB G2AN KIAA0088 LAFLGVCLGITLAVDRSNFKtCEEssFCKRQRsIRPGLsPy
Q14974 T863 Sugiyama KPNB1 NTF97 IHELLTEGRRSKTNKAKtLAtWATKELRKLKNQA_______
Q14978 T610 Sugiyama NOLC1 KIAA0035 NS5ATP13 EAAKEAEtPQAKKIKLQtPNtFPKRKKGEKRAssPFRRVRE
Q14CN4 S138 Sugiyama KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN
Q15021 S1310 Sugiyama NCAPD2 CAPD2 CNAP1 KIAA0159 RACHTRGLDGIKELEIGQAGsQRAPsAKKPSTGSRyQPLAs
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15056 S69 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 LPFNTVQGDIDAIFKDLsIRsVRLVRDKDTDKFKGFCyVEF
Q15084 S230 Sugiyama PDIA6 ERP5 P5 TXNDC7 QTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIFQKGEsPV
Q15084 T223 Sugiyama PDIA6 ERP5 P5 TXNDC7 AAsEVKEQTKGKVKLAAVDAtVNQVLAsRYGIRGFPtIKIF
Q15185 S85 Sugiyama PTGES3 P23 TEBP KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN
Q15293 T144 Sugiyama RCN1 RCN WKDYDRDKDDKISWEEyKQAtyGyyLGNPAEFHDssDHHtF
Q15293 T163 Sugiyama RCN1 RCN AtyGyyLGNPAEFHDssDHHtFKKMLPRDERRFKAADLNGD
Q15560 T254 Sugiyama TCEA2 IRKAMTKEAIREHQMARTGGtQTDLFtCGKCRKKNCTYTQV
Q15631 T67 Sugiyama TSN QGAGFQDIPKRCLKAREHFGtVKTHLTSLKTKFPAEQYYRF
Q16181 T318 Sugiyama SEPTIN7 CDC10 SEPT7 KDVTNNVHyENyRSRKLAAVtyNGVDNNKNKGQLtKsPLAQ
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16775 T292 Sugiyama HAGH GLO2 HAGH1 FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____
Q27J81 T1206 Sugiyama INF2 C14orf151 C14orf173 DtsLDKsFsEDAVtDssGsGtLPRARGRASKGTGKRRKKRP
Q2VIR3 T22 Sugiyama EIF2S3B AGGEAGVtLGQPHLsRQDLttLDVtKLTPLSHEVISRQAtI
Q2VIR3 T41 Sugiyama EIF2S3B ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
Q2VIR3 T430 Sugiyama EIF2S3B sLstGGRVSAVKADLGKIVLtNPVCtEVGEKIALSRRVEKH
Q2VIR3 T435 Sugiyama EIF2S3B GRVSAVKADLGKIVLtNPVCtEVGEKIALSRRVEKHWRLIG
Q2VIR3 T46 Sugiyama EIF2S3B tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHT
Q2VIR3 T9 Sugiyama EIF2S3B ____________MAGGEAGVtLGQPHLsRQDLttLDVtKLT
Q3SY84 S143 Sugiyama KRT71 K6IRS1 KB34 KRT6IRS1 IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE
Q3ZCM7 S75 Sugiyama TUBB8 SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC
Q3ZCM7 T72 Sugiyama TUBB8 NEASGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIF
Q53EL6 S49 Sugiyama PDCD4 H731 ENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKNssR
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q58FF8 T104 Sugiyama HSP90AB2P HSP90BB LTLVDTGIGMTKADLINNLGtIAKFQDQTEYLEEMQVKEVV
Q5QNW6 S39 Sugiyama H2BC18 HIST2H2BF VTKVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q5VTE0 T22 Sugiyama EEF1A1P5 EEF1AL3 GKEKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKF
Q5VTE0 T261 Sugiyama EEF1A1P5 EEF1AL3 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q5XKE5 S155 Sugiyama KRT79 K6L KB38 KRT6L IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA
Q66LE6 S415 Sugiyama PPP2R2D KIAA1541 RASLKPRKVCTGGKRRKDEIsVDsLDFNKKILHTAWHPVDN
Q66LE6 S418 Sugiyama PPP2R2D KIAA1541 LKPRKVCTGGKRRKDEIsVDsLDFNKKILHTAWHPVDNVIA
Q6EEV6 S28 Sugiyama SUMO4 SMT3H4 EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC
Q6PCE3 S175 Sugiyama PGM2L1 BM32A PFVPYAVQKLKAVAGVMItAsHNRKEDNGYKVYWETGAQIT
Q6PKG0 S627 Sugiyama LARP1 KIAA0731 LARP FLFDEEMEQMDGRKNtFtAWsDEEsDyEIDDRDVNKILIVt
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71U36 T73 Sugiyama TUBA1A TUBA3 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71U36 Y83 Sugiyama TUBA1A TUBA3 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7RTS7 S153 Sugiyama KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE
Q7Z417 S655 Sugiyama NUFIP2 KIAA1321 PIG1 LGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsIWNL
Q7Z739 T177 Sugiyama YTHDF3 YPPSSLGRAITDGQAGFGNDtLSKVPGISsIEQGMTGLKIG
Q7Z794 S177 Sugiyama KRT77 KRT1B IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE
Q86UE4 T194 Sugiyama MTDH AEG1 LYRIC KAVQNssRHDGKEVDEGAWEtKISHREKRQQRKRDKVLtDs
Q86UE4 T477 Sugiyama MTDH AEG1 LYRIC stAQDtEELEKEIREDLPVNtsKTRPKQEKAFSLKtIstsD
Q86V81 T148 Sugiyama ALYREF ALY BEF THOC4 EFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQYNG
Q86W92 T968 Sugiyama PPFIBP1 KIAA1230 MRLyEEDDLDRLEQMEDsEGtVRQIGAFSEGINNLTHMLKE
Q86Y46 S145 Sugiyama KRT73 K6IRS3 KB36 KRT6IRS3 IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE
Q8IYD1 T444 Sugiyama GSPT2 ERF3B NRSIDGPIRLPIVDKYKDMGtVVLGKLESGSIFKGQQLVMM
Q8TAE6 T73 EPSD|PSP PPP1R14C KEPI AAAAGQVQQQQQRRHQQGKVtVKYDRKELRKRLVLEEWIVE
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8TDY4 T545 SIGNOR|EPSD|PSP ASAP3 DDEFL1 UPLC1 GTRRDYIMAKYVEHRFARRCtPEPQRLWTAICNRDLLSVLE
Q8TF09 T67 Sugiyama DYNLRB2 DNCL2B DNLC2B ROBLD2 HHLTMKAKSTVRDIDPQNDLtFLRIRSKKHEIMVAPDKEYL
Q8WXX5 S215 Sugiyama DNAJC9 EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL
Q92499 T302 Sugiyama DDX1 FLPNAPKALIVEPSRELAEQtLNNIKQFKKYIDNPKLRELL
Q92688 T105 Sugiyama ANP32B APRIL PHAPI2 EKLPNLTHLNLsGNKLKDIstLEPLKKLECLKsLDLFNCEV
Q92890 S299 Sugiyama UFD1 UFD1L KKVEEDEAGGRFVAFsGEGQsLRKKGRKP____________
Q93079 S39 Sugiyama H2BC9 H2BFJ HIST1H2BH VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q96AY3 T200 Sugiyama FKBP10 FKBP65 PSEC0056 HYNGTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLG
Q96AY3 T203 Sugiyama FKBP10 FKBP65 PSEC0056 GTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGMCP
Q96C86 T318 Sugiyama DCPS DCS1 HINT5 HSPC015 LAEVIENLECDPRHyQQRTLtFALRADDPLLKLLQEAQQS_
Q96C86 Y312 Sugiyama DCPS DCS1 HINT5 HSPC015 VERAHLLAEVIENLECDPRHyQQRTLtFALRADDPLLKLLQ
Q96G46 T167 Sugiyama DUS3L VGRYLETKPADLGPRCVLFEtFGRCPYGVtCRFAGAHLRPE
Q99547 T124 Sugiyama MPHOSPH6 MPP6 TVELDVsDEEMARRyEtLVGtIGKKFARKRDHANYEEDENG
Q99547 Y118 Sugiyama MPHOSPH6 MPP6 EEVEDETVELDVsDEEMARRyEtLVGtIGKKFARKRDHANY
Q99613 T880 Sugiyama EIF3C EIF3S8 AEKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMR
Q99627 T158 Sugiyama COPS8 CSN8 GLPVEEAVKGILEQGWQADstTRMVLPRKPVAGALDVsFNK
Q99733 T58 Sugiyama NAP1L4 NAP2 LAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQVRCA
Q99733 Y55 Sugiyama NAP1L4 NAP2 PRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQV
Q99832 T57 Sugiyama CCT7 CCTH NIP7-1 RTTLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAK
Q99832 T64 Sugiyama CCT7 CCTH NIP7-1 GMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTLVDIAK
Q99848 S270 Sugiyama EBNA1BP2 EBP2 FGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPGKKGSN
Q99877 S39 Sugiyama H2BC15 H2BFD HIST1H2BN VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99879 S39 Sugiyama H2BC14 H2BFE HIST1H2BM INKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q99880 S39 Sugiyama H2BC13 H2BFC HIST1H2BL VTKAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKA
Q9BQE3 T73 Sugiyama TUBA1C TUBA6 FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BQE3 Y83 Sugiyama TUBA1C TUBA6 PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy
Q9BS26 T155 Sugiyama ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 yIRQQKSDPIQEIRDLAEIttLDRSKRNIIGYFEQKDSDNy
Q9BUJ2 S512 Sugiyama HNRNPUL1 E1BAP5 HNRPUL1 IQIAARKKRNyILDQtNVyGsAQRRKMRPFEGFQRKAIVIC
Q9BUL8 S39 EPSD|PSP PDCD10 CCM3 TFAR15 SMPLYAVMYPVFNELERVNLsAAQtLRAAFIKAEKENPGLT
Q9BUL8 T43 EPSD|PSP PDCD10 CCM3 TFAR15 YAVMYPVFNELERVNLsAAQtLRAAFIKAEKENPGLTQDII
Q9BVA1 S75 Sugiyama TUBB2B tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9C0C2 T204 Sugiyama TNKS1BP1 KIAA1741 TAB182 GSRLTFNHDGssRYGPRTyGtTTAPRDEDGstLFRGWsQEG
Q9C0C9 S115 Sugiyama UBE2O KIAA1734 GRGssGCSEAGGAGHEEGRAsPLRRGYVRVQWYPEGVKQHV
Q9C0C9 S87 Sugiyama UBE2O KIAA1734 SGRYRGsVHFGLVRLIHGEDsDsEGEEEGRGssGCSEAGGA
Q9C0C9 S89 Sugiyama UBE2O KIAA1734 RYRGsVHFGLVRLIHGEDsDsEGEEEGRGssGCSEAGGAGH
Q9H0B6 S539 Sugiyama KLC2 sEsDLEDVGPTAEWNGDGsGsLRRSGsFGKLRDALRRsSEM
Q9H0C5 S273 Sugiyama BTBD1 C15orf1 NS5ATP8 QRQQLPVTFGNKQKVLGKALsLIRFPLMTIEEFAAGPAQSG
Q9H173 T125 Sugiyama SIL1 UNQ545/PRO836 QYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEME
Q9H444 T85 Sugiyama CHMP4B C20orf178 SHAX1 ALQALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEV
Q9H444 T88 Sugiyama CHMP4B C20orf178 SHAX1 ALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEVLKN
Q9H788 S124 Sugiyama SH2D4A PPP1R38 SH2A LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD
Q9H788 S187 Sugiyama SH2D4A PPP1R38 SH2A EEKIRSLSSSSRNIQQMLADsINRMKAYAFHQKKESMKKKQ
Q9H788 T313 Sugiyama SH2D4A PPP1R38 SH2A QFLNSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPL
Q9HB71 T209 Sugiyama CACYBP S100A6BP SIP PNAS-107 EGLMNVLKKIyEDGDDDMKRtINKAWVESREKQAKGDTEF_
Q9HCN8 T199 Sugiyama SDF2L1 UNQ1941/PRO4424 GSPIRGQHEVHGMPSANtHNtWKAMEGIFIKPSVEPSAGHD
Q9NP97 T67 Sugiyama DYNLRB1 BITH DNCL2A DNLC2A ROBLD1 HSPC162 HSFILKARStVRDIDPQNDLtFLRIRsKKNEIMVAPDKDYF
Q9NPQ8 T441 Sugiyama RIC8A AARGLMAGGRPEGQysEDEDtDtDEyKEAKAsINPVTGRVE
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQW7 T591 Sugiyama XPNPEP1 XPNPEPL XPNPEPL1 MIDVDSLTDKECDWLNNyHLtCRDVIGKELQKQGRQEALEW
Q9NRX4 T119 Sugiyama PHPT1 PHP14 CGI-202 HSPC141 PAQHAISTEKIKAKyPDyEVtWANDGy______________
Q9NSB2 S178 Sugiyama KRT84 KRTHB4 AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS
Q9NZZ3 T23 Sugiyama CHMP5 C9orf83 SNF7DC2 CGI-34 HSPC177 PNAS-114 PNAS-2 RLFGKAKPKAPPPsLtDCIGtVDsRAEsIDKKISRLDAELV
Q9P0J1 T494 Sugiyama PDP1 PDP PPM2C EDQNAATHLIRHAVGNNEFGtVDHERLSKMLSLPEELARMY
Q9P258 T20 Sugiyama RCC2 KIAA1470 TD60 _MPRKKAAAAAWEEPssGNGtARAGPRKRGGPAGRKRERPE
Q9P289 T178 GPS6|EPSD STK26 MASK MST4 VKLADFGVAGQLtDtQIKRNtFVGtPFWMAPEVIQQSAYDS
Q9P2E9 T684 Sugiyama RRBP1 KIAA1398 EGEAQRLIEILSEKAGIIQDtWHKATQKGDPVAILKRQLEE
Q9UBR2 S195 Sugiyama CTSZ EFKECHAIRNYTLWRVGDYGsLSGREKMMAEIYANGPISCG
Q9UBR2 T172 Sugiyama CTSZ ETCNNYQAKDQECDKFNQCGtCNEFKECHAIRNYTLWRVGD
Q9UGY1 S21 Sugiyama NOL12 MGRNKKKKRDGDDRRPRLVLsFDEEKRREyLTGFHKRKVER
Q9UHA3 T64 Sugiyama RSL24D1 C15orf15 RPL24L My024 RNPRKVRWTKAFRKAAGKELtVDNsFEFEKRRNEPIKYQRE
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UII2 S39 Sugiyama ATP5IF1 ATPI ATPIF1 TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF
Q9UJ70 S76 Sugiyama NAGK AKRKAGVDPLVPLRsLGLsLsGGDQEDAGRILIEELRDRFP
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UNX3 T93 Sugiyama RPL26L1 RPL26P1 VYRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDK
Q9UNX3 T94 Sugiyama RPL26L1 RPL26P1 YRKKyVIyIERVQREKANGttVHVGIHPSKVVITRLKLDKD
Q9UQ35 S2692 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS
Q9UQ35 T848 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 KtPsRQsHSsssPHPKVKsGtPPRQGsItsPQANEQsVtPQ
Q9UQ80 T200 Sugiyama PA2G4 EBP1 TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV
Q9Y281 T91 Sugiyama CFL2 FVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPESAPL
Q9Y281 Y89 Sugiyama CFL2 tsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPESA
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2B0 T100 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL
Q9Y2B0 T132 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF
Q9Y2K2 T221 PSP SIK3 KIAA0999 QSK L19 NIKIADFGFSNLFTPGQLLKtWCGSPPYAAPELFEGKEYDG
Q9Y2T7 T143 Sugiyama YBX2 CSDA3 MSY2 QtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEATNVTGP
Q9Y2W1 S232 Sugiyama THRAP3 BCLAF2 TRAP150 QDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERsPALK
Q9Y2W1 T230 Sugiyama THRAP3 BCLAF2 TRAP150 tsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERsPA
Q9Y3B8 S203 Sugiyama REXO2 SFN SMFN CGI-114 EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK
Q9Y4P1 S383 SIGNOR|EPSD|PSP ATG4B APG4B AUTL1 KIAA0943 DVLNLSLDSSDVERLERFFDsEDEDFEILsL__________
Q9Y570 S265 Sugiyama PPME1 PME1 PP2593 PRO0750 EGsKsIVEGIIEEEEEDEEGsESISKRKKEDDMETKKDHPY
Q9Y5B9 S650 Sugiyama SUPT16H FACT140 FACTP140 KRYKTREAEEKEKEGIVKQDsLVINLNRsNPKLKDLYIRPN
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Q9Y5L4 T79 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B DNSEQKCIAMCMDRyMDAWNtVsRAYNSRLQRERANM____
Q9Y6E0 S149 Sugiyama STK24 MST3 STK3 DETQIATILREILKGLDYLHsEKKIHRDIKAANVLLSEHGE
Q9Y6E0 S46 Sugiyama STK24 MST3 STK3 TNLKADPEELFTKLEKIGKGsFGEVFKGIDNRTQKVVAIKI
Q9Y6E0 T182 Sugiyama STK24 MST3 STK3 VLLSEHGEVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEV
Q9Y6E0 T184 Sugiyama STK24 MST3 STK3 LSEHGEVKLADFGVAGQLtDtQIKRNtFVGTPFWMAPEVIK
Q9Y6E0 T297 Sugiyama STK24 MST3 STK3 AKELLKHKFILRNAKKTsyLtELIDRYKRWKAEQSHDDSSS
Q9Y6E0 Y295 Sugiyama STK24 MST3 STK3 PTAKELLKHKFILRNAKKTsyLtELIDRYKRWKAEQSHDDS
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Cell Cycle R-HSA-1640170 2.029419e-10 9.693 0 0
Apoptotic execution phase R-HSA-75153 3.319205e-09 8.479 1 0
Cell Cycle, Mitotic R-HSA-69278 1.294109e-08 7.888 0 0
Cellular Senescence R-HSA-2559583 1.550986e-08 7.809 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 4.346442e-07 6.362 1 1
Axon guidance R-HSA-422475 3.993004e-07 6.399 0 0
Signal Transduction R-HSA-162582 5.549054e-07 6.256 0 0
Cell Cycle Checkpoints R-HSA-69620 8.531743e-07 6.069 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.135492e-06 5.945 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.135492e-06 5.945 0 0
M Phase R-HSA-68886 1.992776e-06 5.701 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.793973e-06 5.554 0 0
Nervous system development R-HSA-9675108 4.956706e-06 5.305 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 5.660989e-06 5.247 0 0
mRNA 3'-end processing R-HSA-72187 1.171190e-05 4.931 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.155838e-05 4.937 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.274805e-05 4.895 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.353152e-05 4.869 0 0
Signaling by Hippo R-HSA-2028269 1.321425e-05 4.879 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 2.328832e-05 4.633 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 2.705090e-05 4.568 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.665130e-05 4.574 0 0
G2/M DNA damage checkpoint R-HSA-69473 3.033593e-05 4.518 0 0
Signaling by ROBO receptors R-HSA-376176 3.574909e-05 4.447 0 0
Mitotic Prometaphase R-HSA-68877 4.007152e-05 4.397 0 0
Interleukin-12 signaling R-HSA-9020591 4.522709e-05 4.345 0 0
Mitotic Prophase R-HSA-68875 5.046830e-05 4.297 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 7.174345e-05 4.144 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.102994e-04 3.957 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 1.099425e-04 3.959 0 0
Signaling by VEGF R-HSA-194138 1.194058e-04 3.923 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.295762e-04 3.887 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.372298e-04 3.863 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.561485e-04 3.806 0 0
mRNA Splicing - Major Pathway R-HSA-72163 1.561814e-04 3.806 0 0
mRNA Splicing R-HSA-72172 1.520766e-04 3.818 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.685388e-04 3.773 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.926542e-04 3.715 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.901478e-04 3.721 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.183641e-04 3.661 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.406562e-04 3.468 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.343401e-04 3.476 0 0
Interleukin-12 family signaling R-HSA-447115 3.697734e-04 3.432 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.122388e-04 3.385 0 0
Diseases of programmed cell death R-HSA-9645723 4.316548e-04 3.365 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 4.511142e-04 3.346 0 0
Chromatin modifying enzymes R-HSA-3247509 5.218033e-04 3.282 0 0
Rap1 signalling R-HSA-392517 5.115441e-04 3.291 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 5.108091e-04 3.292 0 0
Signaling by ALK in cancer R-HSA-9700206 5.108091e-04 3.292 0 0
Estrogen-dependent gene expression R-HSA-9018519 6.175601e-04 3.209 0 0
HATs acetylate histones R-HSA-3214847 6.324918e-04 3.199 0 0
ESR-mediated signaling R-HSA-8939211 6.795026e-04 3.168 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.931220e-04 3.159 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 7.143481e-04 3.146 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 8.453022e-04 3.073 0 0
G alpha (12/13) signalling events R-HSA-416482 8.395870e-04 3.076 0 0
Regulation of TP53 Activity R-HSA-5633007 8.234822e-04 3.084 0 0
Mitotic Anaphase R-HSA-68882 8.478190e-04 3.072 0 0
EPH-Ephrin signaling R-HSA-2682334 8.979516e-04 3.047 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 9.264292e-04 3.033 0 0
Apoptosis R-HSA-109581 1.011255e-03 2.995 1 0
Chromatin organization R-HSA-4839726 1.129754e-03 2.947 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.163837e-03 2.934 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.166601e-03 2.933 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.290293e-03 2.889 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.366662e-03 2.864 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.613555e-03 2.792 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.643857e-03 2.784 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.932207e-03 2.714 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.915429e-03 2.718 0 0
Semaphorin interactions R-HSA-373755 1.948252e-03 2.710 0 0
Meiotic synapsis R-HSA-1221632 1.961013e-03 2.708 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 2.175967e-03 2.662 0 0
Separation of Sister Chromatids R-HSA-2467813 2.155434e-03 2.666 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.260054e-03 2.646 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 2.263099e-03 2.645 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.312933e-03 2.636 0 0
MECP2 regulates transcription factors R-HSA-9022707 2.578018e-03 2.589 0 0
PRC2 methylates histones and DNA R-HSA-212300 2.516067e-03 2.599 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.583428e-03 2.588 0 0
Kinesins R-HSA-983189 2.711465e-03 2.567 0 0
MAP2K and MAPK activation R-HSA-5674135 3.192206e-03 2.496 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 3.083786e-03 2.511 0 0
DNA methylation R-HSA-5334118 3.297788e-03 2.482 0 0
Signaling downstream of RAS mutants R-HSA-9649948 3.247805e-03 2.488 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 3.247805e-03 2.488 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 3.247805e-03 2.488 0 0
Signaling by RAS mutants R-HSA-6802949 3.247805e-03 2.488 0 0
Post NMDA receptor activation events R-HSA-438064 3.405816e-03 2.468 0 0
Chromosome Maintenance R-HSA-73886 3.440511e-03 2.463 0 0
DNA Double Strand Break Response R-HSA-5693606 3.567822e-03 2.448 0 0
Cap-dependent Translation Initiation R-HSA-72737 3.692269e-03 2.433 0 0
Eukaryotic Translation Initiation R-HSA-72613 3.692269e-03 2.433 0 0
G2/M Checkpoints R-HSA-69481 3.928862e-03 2.406 0 0
Nuclear Envelope Breakdown R-HSA-2980766 3.774179e-03 2.423 0 0
DNA Repair R-HSA-73894 4.061406e-03 2.391 0 0
Programmed Cell Death R-HSA-5357801 4.069485e-03 2.390 1 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 4.085676e-03 2.389 0 0
Interleukin-37 signaling R-HSA-9008059 4.105549e-03 2.387 0 0
FOXO-mediated transcription of cell cycle genes R-HSA-9617828 4.130997e-03 2.384 0 0
Ephrin signaling R-HSA-3928664 4.484257e-03 2.348 0 0
Defective pyroptosis R-HSA-9710421 4.569511e-03 2.340 0 0
Meiosis R-HSA-1500620 4.623464e-03 2.335 0 0
Metalloprotease DUBs R-HSA-5689901 4.686808e-03 2.329 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 5.404235e-03 2.267 0 0
EPHB-mediated forward signaling R-HSA-3928662 5.420370e-03 2.266 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 5.535346e-03 2.257 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 5.665111e-03 2.247 0 0
Formation of a pool of free 40S subunits R-HSA-72689 5.812080e-03 2.236 0 0
AKT phosphorylates targets in the nucleus R-HSA-198693 6.162606e-03 2.210 0 0
Packaging Of Telomere Ends R-HSA-171306 5.843362e-03 2.233 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 6.267075e-03 2.203 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 5.843362e-03 2.233 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 5.843362e-03 2.233 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 6.394869e-03 2.194 0 0
Nucleosome assembly R-HSA-774815 6.394869e-03 2.194 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 6.436993e-03 2.191 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 6.466783e-03 2.189 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 6.466783e-03 2.189 0 0
AURKA Activation by TPX2 R-HSA-8854518 6.493872e-03 2.187 0 0
Deubiquitination R-HSA-5688426 6.751781e-03 2.171 0 0
G-protein mediated events R-HSA-112040 7.418793e-03 2.130 0 0
Eukaryotic Translation Elongation R-HSA-156842 6.957411e-03 2.158 0 0
NRAGE signals death through JNK R-HSA-193648 7.072680e-03 2.150 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 7.033533e-03 2.153 0 0
Peptide chain elongation R-HSA-156902 7.443002e-03 2.128 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 7.514994e-03 2.124 0 0
Signaling by RAF1 mutants R-HSA-9656223 7.621682e-03 2.118 0 0
Breakdown of the nuclear lamina R-HSA-352238 8.027959e-03 2.095 0 0
Homology Directed Repair R-HSA-5693538 8.054906e-03 2.094 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 8.313250e-03 2.080 0 0
Neurodegenerative Diseases R-HSA-8863678 8.342320e-03 2.079 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 8.342320e-03 2.079 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 8.881492e-03 2.052 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 9.046567e-03 2.044 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.018399e-02 1.992 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 1.018559e-02 1.992 0 0
Reproduction R-HSA-1474165 9.911762e-03 2.004 0 0
HDMs demethylate histones R-HSA-3214842 1.030584e-02 1.987 0 0
Long-term potentiation R-HSA-9620244 1.030584e-02 1.987 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.069416e-02 1.971 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.070375e-02 1.970 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.072934e-02 1.969 0 0
Specification of primordial germ cells R-HSA-9827857 1.076926e-02 1.968 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.081067e-02 1.966 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 1.245772e-02 1.905 0 0
HDACs deacetylate histones R-HSA-3214815 1.290593e-02 1.889 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.223998e-02 1.912 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.234487e-02 1.909 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 1.174431e-02 1.930 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.212726e-02 1.916 0 0
Cell-Cell communication R-HSA-1500931 1.260346e-02 1.900 0 0
Telomere Maintenance R-HSA-157579 1.311236e-02 1.882 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.356810e-02 1.867 0 0
Synaptic adhesion-like molecules R-HSA-8849932 1.371440e-02 1.863 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 1.371440e-02 1.863 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.382931e-02 1.859 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.471741e-02 1.832 0 0
Cellular responses to stress R-HSA-2262752 1.508834e-02 1.821 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.533601e-02 1.814 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 1.540034e-02 1.812 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.544163e-02 1.811 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.545584e-02 1.811 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.725382e-02 1.763 0 0
Activation of RAC1 R-HSA-428540 1.688295e-02 1.773 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.726893e-02 1.763 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.654153e-02 1.781 0 0
Meiotic recombination R-HSA-912446 1.555709e-02 1.808 0 0
MAPK family signaling cascades R-HSA-5683057 1.650982e-02 1.782 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 1.734581e-02 1.761 0 0
Type I hemidesmosome assembly R-HSA-446107 1.734581e-02 1.761 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.734581e-02 1.761 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.771621e-02 1.752 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.771621e-02 1.752 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.773558e-02 1.751 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.773558e-02 1.751 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 1.815787e-02 1.741 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 1.815787e-02 1.741 0 0
Eukaryotic Translation Termination R-HSA-72764 1.900416e-02 1.721 0 0
Centrosome maturation R-HSA-380287 1.926445e-02 1.715 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.932736e-02 1.714 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.979094e-02 1.704 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 1.979094e-02 1.704 0 0
Processing of Capped Intronless Pre-mRNA R-HSA-75067 2.186341e-02 1.660 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.180841e-02 1.661 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 2.180841e-02 1.661 0 0
GPER1 signaling R-HSA-9634597 2.146154e-02 1.668 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 2.020135e-02 1.695 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 2.087281e-02 1.680 0 0
Metabolism of RNA R-HSA-8953854 2.036439e-02 1.691 0 0
Influenza Infection R-HSA-168255 2.033950e-02 1.692 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.369734e-02 1.625 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.369734e-02 1.625 0 0
Muscle contraction R-HSA-397014 2.382590e-02 1.623 0 0
Cellular responses to stimuli R-HSA-8953897 2.385249e-02 1.622 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 2.388241e-02 1.622 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 2.405183e-02 1.619 0 0
Processing of Intronless Pre-mRNAs R-HSA-77595 2.490973e-02 1.604 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 2.574255e-02 1.589 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 2.675075e-02 1.573 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 3.009265e-02 1.522 0 0
Diseases of Telomere Maintenance R-HSA-9673013 3.009265e-02 1.522 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 3.009265e-02 1.522 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 3.009265e-02 1.522 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 3.009265e-02 1.522 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 3.009265e-02 1.522 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 3.009265e-02 1.522 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 3.009265e-02 1.522 0 0
Axonal growth stimulation R-HSA-209563 3.057702e-02 1.515 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 2.749797e-02 1.561 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 2.679268e-02 1.572 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 2.679268e-02 1.572 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 2.679268e-02 1.572 0 0
Protein-protein interactions at synapses R-HSA-6794362 2.942458e-02 1.531 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.854486e-02 1.544 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 2.893327e-02 1.539 0 0
Glycolysis R-HSA-70171 2.980813e-02 1.526 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 3.110048e-02 1.507 0 0
Myogenesis R-HSA-525793 3.110048e-02 1.507 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 3.145229e-02 1.502 0 0
Regulation of CDH11 function R-HSA-9762292 3.231060e-02 1.491 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 3.231060e-02 1.491 0 0
Selenocysteine synthesis R-HSA-2408557 3.243839e-02 1.489 0 0
Intracellular signaling by second messengers R-HSA-9006925 3.332684e-02 1.477 0 0
RET signaling R-HSA-8853659 3.337486e-02 1.477 0 0
Calmodulin induced events R-HSA-111933 3.337486e-02 1.477 0 0
CaM pathway R-HSA-111997 3.337486e-02 1.477 0 0
Signaling by PTK6 R-HSA-8848021 3.354560e-02 1.474 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 3.354560e-02 1.474 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.398769e-02 1.469 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 3.425757e-02 1.465 0 0
CREB phosphorylation R-HSA-199920 3.425757e-02 1.465 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 4.060737e-02 1.391 0 0
Recycling pathway of L1 R-HSA-437239 3.785012e-02 1.422 0 0
Viral mRNA Translation R-HSA-192823 3.821715e-02 1.418 0 0
Integrin signaling R-HSA-354192 4.060737e-02 1.391 0 0
G0 and Early G1 R-HSA-1538133 3.512695e-02 1.454 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 4.060737e-02 1.391 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.848063e-02 1.415 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 3.751325e-02 1.426 0 0
Activation of ATR in response to replication stress R-HSA-176187 4.060737e-02 1.391 0 0
Cell junction organization R-HSA-446728 3.645727e-02 1.438 0 0
Cleavage of the damaged purine R-HSA-110331 3.827792e-02 1.417 0 0
Ca-dependent events R-HSA-111996 4.070863e-02 1.390 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 4.070863e-02 1.390 0 0
Depyrimidination R-HSA-73928 4.070863e-02 1.390 0 0
ChREBP activates metabolic gene expression R-HSA-163765 4.209862e-02 1.376 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 4.366185e-02 1.360 0 0
Depurination R-HSA-73927 4.366185e-02 1.360 0 0
Signaling by NTRKs R-HSA-166520 4.472134e-02 1.349 0 0
Signaling by ERBB2 R-HSA-1227986 4.488034e-02 1.348 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 4.507986e-02 1.346 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 4.507986e-02 1.346 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.520122e-02 1.345 0 0
Ub-specific processing proteases R-HSA-5689880 4.607998e-02 1.336 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 4.657562e-02 1.332 0 0
Striated Muscle Contraction R-HSA-390522 4.664622e-02 1.331 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 4.664622e-02 1.331 0 0
RUNX3 regulates WNT signaling R-HSA-8951430 4.715021e-02 1.327 0 0
Binding of TCF/LEF:CTNNB1 to target gene promoters R-HSA-4411364 4.715021e-02 1.327 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 4.715021e-02 1.327 0 0
TNFR1-mediated ceramide production R-HSA-5626978 4.797789e-02 1.319 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 4.922393e-02 1.308 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 4.948157e-02 1.306 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 4.954398e-02 1.305 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 4.954398e-02 1.305 0 0
PLC beta mediated events R-HSA-112043 4.964245e-02 1.304 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.984349e-02 1.302 0 0
Base Excision Repair R-HSA-73884 4.984349e-02 1.302 0 0
L1CAM interactions R-HSA-373760 5.033660e-02 1.298 0 0
RMTs methylate histone arginines R-HSA-3214858 5.165667e-02 1.287 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 6.208393e-02 1.207 0 0
Transport of glycerol from adipocytes to the liver by Aquaporins R-HSA-432030 6.208393e-02 1.207 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 5.349207e-02 1.272 0 0
Signaling by GSK3beta mutants R-HSA-5339716 5.349207e-02 1.272 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 5.404108e-02 1.267 0 0
Nuclear import of Rev protein R-HSA-180746 5.326208e-02 1.274 0 0
Ion homeostasis R-HSA-5578775 5.414474e-02 1.266 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 5.982814e-02 1.223 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 5.326208e-02 1.274 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 5.349207e-02 1.272 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 5.593940e-02 1.252 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 5.193285e-02 1.285 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 5.723879e-02 1.242 0 0
DAG and IP3 signaling R-HSA-1489509 5.781613e-02 1.238 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 5.191002e-02 1.285 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 5.326208e-02 1.274 0 0
Gene Silencing by RNA R-HSA-211000 5.594844e-02 1.252 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 6.237451e-02 1.205 0 0
Adrenoceptors R-HSA-390696 6.237451e-02 1.205 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 6.237451e-02 1.205 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 6.237451e-02 1.205 0 0
Death Receptor Signaling R-HSA-73887 6.436633e-02 1.191 0 0
Diseases of DNA repair R-HSA-9675135 6.444754e-02 1.191 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 6.541504e-02 1.184 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 6.650416e-02 1.177 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 6.650416e-02 1.177 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 6.650416e-02 1.177 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 6.650416e-02 1.177 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 6.650416e-02 1.177 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 6.650416e-02 1.177 0 0
Regulation of TP53 Degradation R-HSA-6804757 6.828320e-02 1.166 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.920205e-02 1.160 0 0
IRS activation R-HSA-74713 6.923291e-02 1.160 0 0
G2 Phase R-HSA-68911 6.923291e-02 1.160 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 6.923291e-02 1.160 0 0
Negative regulation of MAPK pathway R-HSA-5675221 7.031821e-02 1.153 0 0
FOXO-mediated transcription R-HSA-9614085 7.193146e-02 1.143 0 0
Mitotic G2-G2/M phases R-HSA-453274 7.334837e-02 1.135 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.406079e-02 1.130 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 7.587251e-02 1.120 0 0
RNA Polymerase I Transcription R-HSA-73864 7.699175e-02 1.114 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 7.831903e-02 1.106 0 0
Regulation of PTEN gene transcription R-HSA-8943724 7.924285e-02 1.101 0 0
p75NTR regulates axonogenesis R-HSA-193697 7.986842e-02 1.098 0 0
ALK mutants bind TKIs R-HSA-9700645 7.986842e-02 1.098 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 8.012518e-02 1.096 0 0
Interaction between L1 and Ankyrins R-HSA-445095 8.012518e-02 1.096 0 0
RAF/MAP kinase cascade R-HSA-5673001 8.020061e-02 1.096 0 0
Phosphorylation of Emi1 R-HSA-176417 9.398418e-02 1.027 0 0
Signal attenuation R-HSA-74749 9.951840e-02 1.002 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 9.951840e-02 1.002 0 0
Folding of actin by CCT/TriC R-HSA-390450 9.951840e-02 1.002 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 8.111926e-02 1.091 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 8.111926e-02 1.091 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 8.111926e-02 1.091 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 8.111926e-02 1.091 0 0
Regulation of KIT signaling R-HSA-1433559 9.729520e-02 1.012 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 9.729520e-02 1.012 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 9.229428e-02 1.035 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 8.631784e-02 1.064 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 8.363618e-02 1.078 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 9.229428e-02 1.035 0 0
Signaling by EGFR R-HSA-177929 9.520508e-02 1.021 0 0
DNA Damage Bypass R-HSA-73893 8.724997e-02 1.059 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 8.450694e-02 1.073 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 9.193879e-02 1.037 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 8.454321e-02 1.073 0 0
mTORC1-mediated signalling R-HSA-166208 8.631784e-02 1.064 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 8.575293e-02 1.067 0 0
Opioid Signalling R-HSA-111885 1.005778e-01 0.997 0 0
Membrane Trafficking R-HSA-199991 8.503544e-02 1.070 0 0
Signaling by Nuclear Receptors R-HSA-9006931 9.980725e-02 1.001 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 9.608622e-02 1.017 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 9.398418e-02 1.027 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 9.513842e-02 1.022 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 9.951840e-02 1.002 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 9.323309e-02 1.030 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 9.323309e-02 1.030 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 8.100146e-02 1.092 0 0
Regulation of TP53 Expression R-HSA-6804754 1.013085e-01 0.994 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.013085e-01 0.994 0 0
Potassium transport channels R-HSA-1296067 1.013085e-01 0.994 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.013442e-01 0.994 0 0
Platelet calcium homeostasis R-HSA-418360 1.028672e-01 0.988 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 1.028672e-01 0.988 0 0
RAF activation R-HSA-5673000 1.049070e-01 0.979 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 1.056134e-01 0.976 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.063875e-01 0.973 0 0
UCH proteinases R-HSA-5689603 1.063875e-01 0.973 0 0
Ribosome-associated quality control R-HSA-9948299 1.064072e-01 0.973 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 1.126128e-01 0.948 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.126128e-01 0.948 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.149661e-01 0.939 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.149661e-01 0.939 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 1.149661e-01 0.939 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.154540e-01 0.938 0 0
Activation of BH3-only proteins R-HSA-114452 1.154540e-01 0.938 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.165863e-01 0.933 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.165892e-01 0.933 0 0
Oncogene Induced Senescence R-HSA-2559585 1.165892e-01 0.933 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.170897e-01 0.931 0 0
Glucose metabolism R-HSA-70326 1.203654e-01 0.919 0 0
Signaling by APC mutants R-HSA-4839744 1.211695e-01 0.917 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 1.211695e-01 0.917 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 1.211695e-01 0.917 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 1.211695e-01 0.917 0 0
Interleukin-2 signaling R-HSA-9020558 1.211695e-01 0.917 0 0
Leukotriene receptors R-HSA-391906 1.217924e-01 0.914 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 1.226995e-01 0.911 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 1.230942e-01 0.910 0 0
Nephrin family interactions R-HSA-373753 1.230942e-01 0.910 0 0
Drug resistance of KIT mutants R-HSA-9669937 1.254243e-01 0.902 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.254243e-01 0.902 0 0
KIT mutants bind TKIs R-HSA-9669921 1.254243e-01 0.902 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.254243e-01 0.902 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.254243e-01 0.902 0 0
Dasatinib-resistant KIT mutants R-HSA-9669914 1.254243e-01 0.902 0 0
Imatinib-resistant KIT mutants R-HSA-9669917 1.254243e-01 0.902 0 0
Regorafenib-resistant KIT mutants R-HSA-9669929 1.254243e-01 0.902 0 0
Sorafenib-resistant KIT mutants R-HSA-9669936 1.254243e-01 0.902 0 0
APC truncation mutants are not K63 polyubiquitinated R-HSA-5467333 1.254243e-01 0.902 0 0
Loss of function of TP53 in cancer due to loss of tetramerization ability R-HSA-9723905 1.254243e-01 0.902 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.254243e-01 0.902 0 0
Nilotinib-resistant KIT mutants R-HSA-9669926 1.254243e-01 0.902 0 0
Defective translocation of RB1 mutants to the nucleus R-HSA-9661070 1.254243e-01 0.902 0 0
Loss of Function of TP53 in Cancer R-HSA-9723907 1.254243e-01 0.902 0 0
Sunitinib-resistant KIT mutants R-HSA-9669934 1.254243e-01 0.902 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.254243e-01 0.902 0 0
Masitinib-resistant KIT mutants R-HSA-9669924 1.254243e-01 0.902 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.254243e-01 0.902 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.454502e-01 0.837 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 1.454502e-01 0.837 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 1.521768e-01 0.818 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 1.521768e-01 0.818 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 1.446353e-01 0.840 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.340455e-01 0.873 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.544300e-01 0.811 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 1.544300e-01 0.811 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 1.582536e-01 0.801 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 1.426286e-01 0.846 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 1.288275e-01 0.890 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 1.288275e-01 0.890 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 1.578274e-01 0.802 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.419790e-01 0.848 0 0
Translation initiation complex formation R-HSA-72649 1.350727e-01 0.869 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.575403e-01 0.803 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.648958e-01 0.783 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.259134e-01 0.900 0 0
G2/M Transition R-HSA-69275 1.252310e-01 0.902 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 1.401602e-01 0.853 0 0
MHC class II antigen presentation R-HSA-2132295 1.648958e-01 0.783 0 0
Netrin-1 signaling R-HSA-373752 1.660079e-01 0.780 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.419790e-01 0.848 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 1.340455e-01 0.873 0 0
Killing mechanisms R-HSA-9664420 1.340455e-01 0.873 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.284601e-01 0.891 0 0
MTOR signalling R-HSA-165159 1.401566e-01 0.853 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 1.340455e-01 0.873 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.387667e-01 0.858 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 1.403939e-01 0.853 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 1.589365e-01 0.799 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 1.403939e-01 0.853 0 0
Gene expression (Transcription) R-HSA-74160 1.505591e-01 0.822 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.454502e-01 0.837 0 0
Neuronal System R-HSA-112316 1.586153e-01 0.800 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.471673e-01 0.832 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 1.578274e-01 0.802 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.488771e-01 0.827 0 0
NGF-stimulated transcription R-HSA-9031628 1.377909e-01 0.861 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.436135e-01 0.843 0 0
Signaling by AMER1 mutants R-HSA-4839748 1.446353e-01 0.840 0 0
Signaling by AXIN mutants R-HSA-4839735 1.446353e-01 0.840 0 0
TRP channels R-HSA-3295583 1.426286e-01 0.846 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.575403e-01 0.803 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.582536e-01 0.801 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.573541e-01 0.803 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 1.350727e-01 0.869 0 0
Regulation of FOXO transcriptional activity by acetylation R-HSA-9617629 1.697067e-01 0.770 0 0
Polymerase switching R-HSA-69091 1.697067e-01 0.770 0 0
Leading Strand Synthesis R-HSA-69109 1.697067e-01 0.770 0 0
Role of second messengers in netrin-1 signaling R-HSA-418890 1.697067e-01 0.770 0 0
Signaling by LTK R-HSA-9842663 1.697067e-01 0.770 0 0
RNA Polymerase II Transcription R-HSA-73857 1.698444e-01 0.770 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 1.699266e-01 0.770 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.733869e-01 0.761 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 1.733869e-01 0.761 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 1.760021e-01 0.754 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 1.760021e-01 0.754 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 1.760021e-01 0.754 0 0
Pyroptosis R-HSA-5620971 1.760458e-01 0.754 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.797376e-01 0.745 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.804518e-01 0.744 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.814721e-01 0.741 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.817854e-01 0.740 0 0
RSK activation R-HSA-444257 1.846444e-01 0.734 0 0
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs R-HSA-77588 1.846444e-01 0.734 0 0
Sodium/Proton exchangers R-HSA-425986 1.846444e-01 0.734 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.847915e-01 0.733 0 0
Neurexins and neuroligins R-HSA-6794361 1.878114e-01 0.726 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 2.351238e-01 0.629 0 0
Defective Mismatch Repair Associated With MSH3 R-HSA-5632927 2.351238e-01 0.629 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 2.351238e-01 0.629 0 0
Hereditary fructose intolerance R-HSA-5657560 2.351238e-01 0.629 0 0
TFAP2 (AP-2) family regulates transcription of cell cycle factors R-HSA-8866911 1.926598e-01 0.715 0 0
Regulation of gap junction activity R-HSA-191650 1.926598e-01 0.715 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 1.926598e-01 0.715 0 0
NADE modulates death signalling R-HSA-205025 1.926598e-01 0.715 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 1.926598e-01 0.715 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.926598e-01 0.715 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 1.926598e-01 0.715 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 1.926598e-01 0.715 0 0
PI and PC transport between ER and Golgi membranes R-HSA-1483196 3.310690e-01 0.480 0 0
Signaling by juxtamembrane domain KIT mutants R-HSA-9669935 3.310690e-01 0.480 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 3.310690e-01 0.480 0 0
Signaling by extracellular domain mutants of KIT R-HSA-9680187 3.310690e-01 0.480 0 0
Abasic sugar-phosphate removal via the single-nucleotide replacement pathway R-HSA-73930 3.310690e-01 0.480 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 3.310690e-01 0.480 0 0
MPS IIID - Sanfilippo syndrome D R-HSA-2206305 3.310690e-01 0.480 0 0
Signaling by kinase domain mutants of KIT R-HSA-9669933 3.310690e-01 0.480 0 0
Intestinal infectious diseases R-HSA-8942233 3.310690e-01 0.480 0 0
Defective SLC6A2 causes orthostatic intolerance (OI) R-HSA-5619109 3.310690e-01 0.480 0 0
Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) R-HSA-5619054 3.310690e-01 0.480 0 0
TWIK-releated acid-sensitive K+ channel (TASK) R-HSA-1299316 3.310690e-01 0.480 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5619081 3.310690e-01 0.480 0 0
Defective CD320 causes MMATC R-HSA-3359485 3.310690e-01 0.480 0 0
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) R-HSA-5660724 3.310690e-01 0.480 0 0
MyD88 deficiency (TLR5) R-HSA-5602680 3.310690e-01 0.480 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 3.310690e-01 0.480 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 3.310690e-01 0.480 0 0
Trafficking of myristoylated proteins to the cilium R-HSA-5624138 2.414743e-01 0.617 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.414743e-01 0.617 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.414743e-01 0.617 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 2.187113e-01 0.660 0 0
WNT mediated activation of DVL R-HSA-201688 2.187113e-01 0.660 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 2.907490e-01 0.536 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.149838e-01 0.382 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.149838e-01 0.382 0 0
Interaction between PHLDA1 and AURKA R-HSA-8854521 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.149838e-01 0.382 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.149838e-01 0.382 0 0
Mitotic Metaphase/Anaphase Transition R-HSA-68881 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.149838e-01 0.382 0 0
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) R-HSA-5619089 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.149838e-01 0.382 0 0
HHAT G278V doesn't palmitoylate Hh-Np R-HSA-5658034 4.149838e-01 0.382 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.149838e-01 0.382 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 2.539176e-01 0.595 0 0
PI3K/AKT activation R-HSA-198203 2.539176e-01 0.595 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 3.396010e-01 0.469 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 3.396010e-01 0.469 0 0
G2/M DNA replication checkpoint R-HSA-69478 3.396010e-01 0.469 0 0
Polo-like kinase mediated events R-HSA-156711 1.986340e-01 0.702 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 1.986340e-01 0.702 0 0
PKA activation in glucagon signalling R-HSA-164378 1.986340e-01 0.702 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 2.898366e-01 0.538 0 0
DCC mediated attractive signaling R-HSA-418885 2.522932e-01 0.598 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 2.522932e-01 0.598 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 2.221908e-01 0.653 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.972174e-01 0.705 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.179176e-01 0.662 0 0
Deadenylation of mRNA R-HSA-429947 2.179176e-01 0.662 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 2.465329e-01 0.608 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 2.465329e-01 0.608 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 2.465329e-01 0.608 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 2.465329e-01 0.608 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 3.260815e-01 0.487 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 3.260815e-01 0.487 0 0
Inhibition of replication initiation of damaged DNA by RB1/E2F1 R-HSA-113501 3.260815e-01 0.487 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 3.260815e-01 0.487 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.873613e-01 0.412 0 0
Netrin mediated repulsion signals R-HSA-418886 3.873613e-01 0.412 0 0
SOS-mediated signalling R-HSA-112412 3.873613e-01 0.412 0 0
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose R-HSA-9031528 3.873613e-01 0.412 0 0
SLBP independent Processing of Histone Pre-mRNAs R-HSA-111367 3.873613e-01 0.412 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 3.873613e-01 0.412 0 0
TFAP2 (AP-2) family regulates transcription of other transcription factors R-HSA-8866906 4.883761e-01 0.311 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 4.883761e-01 0.311 0 0
Invadopodia formation R-HSA-8941237 4.883761e-01 0.311 0 0
Classical Kir channels R-HSA-1296053 4.883761e-01 0.311 0 0
Defective GCLC causes HAGGSD R-HSA-5578999 4.883761e-01 0.311 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.896000e-01 0.722 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 2.124377e-01 0.673 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 2.124377e-01 0.673 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 2.393079e-01 0.621 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 3.112093e-01 0.507 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 3.112093e-01 0.507 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 3.623075e-01 0.441 0 0
Disorders of Nervous System Development R-HSA-9697154 3.623075e-01 0.441 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 3.623075e-01 0.441 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 3.623075e-01 0.441 0 0
Pervasive developmental disorders R-HSA-9005895 3.623075e-01 0.441 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 2.970091e-01 0.527 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 3.411723e-01 0.467 0 0
Removal of the Flap Intermediate from the C-strand R-HSA-174437 3.411723e-01 0.467 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 4.335355e-01 0.363 0 0
Activation of RAS in B cells R-HSA-1169092 4.335355e-01 0.363 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 4.335355e-01 0.363 0 0
FGFR1b ligand binding and activation R-HSA-190370 4.335355e-01 0.363 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 4.335355e-01 0.363 0 0
Activation of GABAB receptors R-HSA-991365 2.325418e-01 0.633 0 0
snRNP Assembly R-HSA-191859 1.945347e-01 0.711 0 0
Metabolism of non-coding RNA R-HSA-194441 1.945347e-01 0.711 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.076768e-01 0.683 0 0
Telomere Extension By Telomerase R-HSA-171319 3.066556e-01 0.513 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 3.982136e-01 0.400 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.298399e-01 0.482 0 0
Dual Incision in GG-NER R-HSA-5696400 3.129994e-01 0.504 0 0
Activation of the pre-replicative complex R-HSA-68962 3.532325e-01 0.452 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 3.751461e-01 0.426 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 3.751461e-01 0.426 0 0
E2F mediated regulation of DNA replication R-HSA-113510 4.011418e-01 0.397 0 0
Removal of the Flap Intermediate R-HSA-69166 4.335411e-01 0.363 0 0
Gap junction degradation R-HSA-190873 4.777700e-01 0.321 0 0
HCN channels R-HSA-1296061 5.525648e-01 0.258 0 0
AKT-mediated inactivation of FOXO1A R-HSA-211163 5.525648e-01 0.258 0 0
RUNX3 regulates BCL2L11 (BIM) transcription R-HSA-8952158 5.525648e-01 0.258 0 0
Inhibition of TSC complex formation by PKB R-HSA-165181 5.525648e-01 0.258 0 0
ATP sensitive Potassium channels R-HSA-1296025 5.525648e-01 0.258 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 5.525648e-01 0.258 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 5.525648e-01 0.258 0 0
Nuclear Receptor transcription pathway R-HSA-383280 2.690745e-01 0.570 0 0
G1/S-Specific Transcription R-HSA-69205 3.555638e-01 0.449 0 0
Downstream signal transduction R-HSA-186763 3.767415e-01 0.424 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 3.767415e-01 0.424 0 0
Trafficking of AMPA receptors R-HSA-399719 3.767415e-01 0.424 0 0
Tight junction interactions R-HSA-420029 4.013236e-01 0.397 0 0
Co-inhibition by CTLA4 R-HSA-389513 4.308085e-01 0.366 0 0
Voltage gated Potassium channels R-HSA-1296072 3.770615e-01 0.424 0 0
Translesion synthesis by REV1 R-HSA-110312 4.680725e-01 0.330 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.273731e-01 0.369 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 3.563763e-01 0.448 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 3.555742e-01 0.449 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 4.237607e-01 0.373 0 0
Binding and entry of HIV virion R-HSA-173107 5.198249e-01 0.284 0 0
2-LTR circle formation R-HSA-164843 5.198249e-01 0.284 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 5.198249e-01 0.284 0 0
Activation of PPARGC1A (PGC-1alpha) by phosphorylation R-HSA-2151209 5.198249e-01 0.284 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 5.198249e-01 0.284 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 4.531906e-01 0.344 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 4.531906e-01 0.344 0 0
Translesion synthesis by POLI R-HSA-5656121 5.016282e-01 0.300 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.016282e-01 0.300 0 0
Phosphorylation of the APC/C R-HSA-176412 5.016282e-01 0.300 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 5.016282e-01 0.300 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 3.850015e-01 0.415 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 4.365625e-01 0.360 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 4.887828e-01 0.311 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.564359e-01 0.341 0 0
HCMV Early Events R-HSA-9609690 3.655209e-01 0.437 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 4.568922e-01 0.340 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 4.840724e-01 0.315 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 5.340643e-01 0.272 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 5.340643e-01 0.272 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.340643e-01 0.272 0 0
Translesion synthesis by POLK R-HSA-5655862 5.340643e-01 0.272 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.340643e-01 0.272 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 5.595509e-01 0.252 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 5.595509e-01 0.252 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 5.595509e-01 0.252 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.875860e-01 0.312 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 5.283486e-01 0.277 0 0
Neutrophil degranulation R-HSA-6798695 4.199181e-01 0.377 0 0
Interleukin receptor SHC signaling R-HSA-912526 5.441790e-01 0.264 0 0
Dual incision in TC-NER R-HSA-6782135 5.239637e-01 0.281 0 0
Regulation of endogenous retroelements R-HSA-9842860 5.493699e-01 0.260 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 4.901661e-01 0.310 0 0
Regulation of mitotic cell cycle R-HSA-453276 4.901661e-01 0.310 0 0
Early Phase of HIV Life Cycle R-HSA-162594 2.715192e-01 0.566 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 1.971683e-01 0.705 0 0
Chaperonin-mediated protein folding R-HSA-390466 3.108364e-01 0.507 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 5.066328e-01 0.295 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 3.369084e-01 0.472 0 0
Adipogenesis R-HSA-9843745 3.306168e-01 0.481 0 0
G1/S Transition R-HSA-69206 5.089832e-01 0.293 0 0
Specification of the neural plate border R-HSA-9834899 2.221908e-01 0.653 0 0
Extension of Telomeres R-HSA-180786 1.945347e-01 0.711 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.228648e-01 0.491 0 0
Signaling by SCF-KIT R-HSA-1433557 3.766222e-01 0.424 0 0
Lagging Strand Synthesis R-HSA-69186 2.715192e-01 0.566 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 3.129994e-01 0.504 0 0
EGFR downregulation R-HSA-182971 5.523819e-01 0.258 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.465329e-01 0.608 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 3.534267e-01 0.452 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 3.172880e-01 0.499 0 0
G alpha (s) signalling events R-HSA-418555 4.059937e-01 0.391 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 2.858792e-01 0.544 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 3.260815e-01 0.487 0 0
GABA B receptor activation R-HSA-977444 2.325418e-01 0.633 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 3.369084e-01 0.472 0 0
Termination of translesion DNA synthesis R-HSA-5656169 5.037594e-01 0.298 0 0
Transcriptional regulation of testis differentiation R-HSA-9690406 5.340643e-01 0.272 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.391003e-01 0.268 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 2.393079e-01 0.621 0 0
Extrinsic Pathway of Fibrin Clot Formation R-HSA-140834 5.525648e-01 0.258 0 0
TGFBR3 expression R-HSA-9839394 4.013236e-01 0.397 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.964780e-01 0.528 0 0
Epigenetic regulation of gene expression R-HSA-212165 2.024260e-01 0.694 0 0
Nucleotide Excision Repair R-HSA-5696398 4.021504e-01 0.396 0 0
Developmental Cell Lineages R-HSA-9734767 4.521435e-01 0.345 0 0
Integration of provirus R-HSA-162592 3.260815e-01 0.487 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 3.112093e-01 0.507 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 4.335411e-01 0.363 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 3.050826e-01 0.516 0 0
Processive synthesis on the lagging strand R-HSA-69183 4.680725e-01 0.330 0 0
Protein folding R-HSA-391251 3.944425e-01 0.404 0 0
Resolution of D-Loop Structures R-HSA-5693537 2.920741e-01 0.535 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 5.377629e-01 0.269 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 5.523819e-01 0.258 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 2.837743e-01 0.547 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 2.187113e-01 0.660 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 2.393079e-01 0.621 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 2.325418e-01 0.633 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 4.237607e-01 0.373 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 5.198249e-01 0.284 0 0
GABA receptor activation R-HSA-977443 4.274863e-01 0.369 0 0
Disorders of Developmental Biology R-HSA-9675151 5.340643e-01 0.272 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 5.441790e-01 0.264 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 1.896000e-01 0.722 0 0
IGF1R signaling cascade R-HSA-2428924 4.976341e-01 0.303 0 0
GAB1 signalosome R-HSA-180292 3.712092e-01 0.430 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 2.002070e-01 0.699 0 0
Activation of NOXA and translocation to mitochondria R-HSA-111448 1.926598e-01 0.715 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.815138e-01 0.551 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.873613e-01 0.412 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 3.873613e-01 0.412 0 0
DNA strand elongation R-HSA-69190 2.512988e-01 0.600 0 0
Nuclear RNA decay R-HSA-9930044 2.714831e-01 0.566 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 1.945347e-01 0.711 0 0
Lysosphingolipid and LPA receptors R-HSA-419408 4.680725e-01 0.330 0 0
Signalling to RAS R-HSA-167044 4.600646e-01 0.337 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 5.168523e-01 0.287 0 0
Signal amplification R-HSA-392518 1.896000e-01 0.722 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 2.612925e-01 0.583 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 2.808545e-01 0.552 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 4.702472e-01 0.328 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 2.221908e-01 0.653 0 0
Ca2+ pathway R-HSA-4086398 2.952331e-01 0.530 0 0
S Phase R-HSA-69242 3.822981e-01 0.418 0 0
HIV Life Cycle R-HSA-162587 4.013908e-01 0.396 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 4.901661e-01 0.310 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 1.926598e-01 0.715 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.414743e-01 0.617 0 0
PKA activation R-HSA-163615 1.986340e-01 0.702 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 2.715192e-01 0.566 0 0
Translesion Synthesis by POLH R-HSA-110320 4.011418e-01 0.397 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 4.777700e-01 0.321 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.767415e-01 0.424 0 0
Telomere C-strand synthesis initiation R-HSA-174430 4.680725e-01 0.330 0 0
Passive transport by Aquaporins R-HSA-432047 5.340643e-01 0.272 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 5.529808e-01 0.257 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 3.228648e-01 0.491 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 5.148583e-01 0.288 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 2.064223e-01 0.685 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 3.411723e-01 0.467 0 0
Platelet activation, signaling and aggregation R-HSA-76002 3.592377e-01 0.445 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 3.112093e-01 0.507 0 0
Integration of energy metabolism R-HSA-163685 2.465728e-01 0.608 0 0
Activation of HOX genes during differentiation R-HSA-5619507 2.984261e-01 0.525 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 2.984261e-01 0.525 0 0
Cilium Assembly R-HSA-5617833 1.939914e-01 0.712 0 0
DNA Replication Pre-Initiation R-HSA-69002 2.751965e-01 0.560 0 0
Repression of WNT target genes R-HSA-4641265 3.623075e-01 0.441 0 0
Signaling by FGFR1 in disease R-HSA-5655302 4.840724e-01 0.315 0 0
Organelle biogenesis and maintenance R-HSA-1852241 3.231909e-01 0.491 0 0
TP53 Regulates Transcription of Caspase Activators and Caspases R-HSA-6803207 2.815138e-01 0.551 0 0
Cyclin D associated events in G1 R-HSA-69231 2.666125e-01 0.574 0 0
G1 Phase R-HSA-69236 2.666125e-01 0.574 0 0
Generic Transcription Pathway R-HSA-212436 5.337508e-01 0.273 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.961605e-01 0.707 0 0
G alpha (z) signalling events R-HSA-418597 4.691329e-01 0.329 0 0
Regulation of insulin secretion R-HSA-422356 4.938749e-01 0.306 0 0
GPVI-mediated activation cascade R-HSA-114604 5.156340e-01 0.288 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.131494e-01 0.384 0 0
TNF signaling R-HSA-75893 4.875860e-01 0.312 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 1.961605e-01 0.707 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 3.260815e-01 0.487 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.393079e-01 0.621 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 4.335355e-01 0.363 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 4.335355e-01 0.363 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.129994e-01 0.504 0 0
GP1b-IX-V activation signalling R-HSA-430116 4.777700e-01 0.321 0 0
Calcineurin activates NFAT R-HSA-2025928 4.777700e-01 0.321 0 0
Aggrephagy R-HSA-9646399 4.416096e-01 0.355 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.675031e-01 0.246 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.972174e-01 0.705 0 0
Potassium Channels R-HSA-1296071 4.655976e-01 0.332 0 0
Transmission across Chemical Synapses R-HSA-112315 2.932210e-01 0.533 0 0
MyD88-independent TLR4 cascade R-HSA-166166 5.680122e-01 0.246 0 0
Signaling by WNT R-HSA-195721 2.216839e-01 0.654 0 0
PERK regulates gene expression R-HSA-381042 3.341865e-01 0.476 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 5.680122e-01 0.246 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 2.187113e-01 0.660 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.940156e-01 0.712 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.629362e-01 0.334 0 0
Host Interactions of HIV factors R-HSA-162909 3.931634e-01 0.405 0 0
Assembly of the pre-replicative complex R-HSA-68867 3.109494e-01 0.507 0 0
Cardiac conduction R-HSA-5576891 1.919254e-01 0.717 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 2.539176e-01 0.595 0 0
POLB-Dependent Long Patch Base Excision Repair R-HSA-110362 3.260815e-01 0.487 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.714831e-01 0.566 0 0
Transcriptional activation of p53 responsive genes R-HSA-69560 5.525648e-01 0.258 0 0
Transcriptional activation of cell cycle inhibitor p21 R-HSA-69895 5.525648e-01 0.258 0 0
p38MAPK events R-HSA-171007 4.680725e-01 0.330 0 0
Chylomicron assembly R-HSA-8963888 5.595509e-01 0.252 0 0
Signalling to ERKs R-HSA-187687 3.341865e-01 0.476 0 0
DNA Replication R-HSA-69306 2.854251e-01 0.545 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 4.273731e-01 0.369 0 0
Platelet homeostasis R-HSA-418346 4.154668e-01 0.381 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.414743e-01 0.617 0 0
Receptor Mediated Mitophagy R-HSA-8934903 2.539176e-01 0.595 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 3.396010e-01 0.469 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 3.260815e-01 0.487 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 2.124377e-01 0.673 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.002070e-01 0.699 0 0
tRNA processing in the nucleus R-HSA-6784531 3.398417e-01 0.469 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 4.786813e-01 0.320 0 0
Signaling by TGFBR3 R-HSA-9839373 4.365625e-01 0.360 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 3.298399e-01 0.482 0 0
Interleukin-2 family signaling R-HSA-451927 4.416096e-01 0.355 0 0
Parasitic Infection Pathways R-HSA-9824443 5.429753e-01 0.265 0 0
Leishmania infection R-HSA-9658195 5.429753e-01 0.265 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 3.532325e-01 0.452 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 4.777700e-01 0.321 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 3.679859e-01 0.434 0 0
Rab regulation of trafficking R-HSA-9007101 4.895314e-01 0.310 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 1.930549e-01 0.714 0 0
Frs2-mediated activation R-HSA-170968 3.982136e-01 0.400 0 0
Developmental Biology R-HSA-1266738 3.742810e-01 0.427 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 4.938749e-01 0.306 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 4.938749e-01 0.306 0 0
Prolonged ERK activation events R-HSA-169893 5.016282e-01 0.300 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 2.837743e-01 0.547 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 4.938749e-01 0.306 0 0
Inhibition of PKR R-HSA-169131 2.351238e-01 0.629 0 0
Inhibition of Host mRNA Processing and RNA Silencing R-HSA-168315 3.310690e-01 0.480 0 0
TGFBR3 regulates FGF2 signaling R-HSA-9839397 3.310690e-01 0.480 0 0
ARMS-mediated activation R-HSA-170984 2.187113e-01 0.660 0 0
Signalling to ERK5 R-HSA-198765 4.149838e-01 0.382 0 0
Regulation of cortical dendrite branching R-HSA-8985801 4.149838e-01 0.382 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 1.961605e-01 0.707 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.396010e-01 0.469 0 0
Bicarbonate transporters R-HSA-425381 2.898366e-01 0.538 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.873613e-01 0.412 0 0
Activation of BIM and translocation to mitochondria R-HSA-111446 4.883761e-01 0.311 0 0
MET interacts with TNS proteins R-HSA-8875513 4.883761e-01 0.311 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 4.335355e-01 0.363 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.841911e-01 0.546 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 3.751461e-01 0.426 0 0
Unwinding of DNA R-HSA-176974 4.777700e-01 0.321 0 0
Activation of the TFAP2 (AP-2) family of transcription factors R-HSA-8866907 4.777700e-01 0.321 0 0
Dopamine receptors R-HSA-390651 5.525648e-01 0.258 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.770615e-01 0.424 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.241098e-01 0.489 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 5.198249e-01 0.284 0 0
Ionotropic activity of kainate receptors R-HSA-451306 5.595509e-01 0.252 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 4.802545e-01 0.319 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.863927e-01 0.543 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 5.084624e-01 0.294 0 0
Selective autophagy R-HSA-9663891 5.371385e-01 0.270 0 0
Cell-cell junction organization R-HSA-421270 2.905138e-01 0.537 0 0
Adherens junctions interactions R-HSA-418990 3.130394e-01 0.504 0 0
Cellular response to starvation R-HSA-9711097 2.053752e-01 0.687 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 4.887828e-01 0.311 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 4.273731e-01 0.369 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 5.016282e-01 0.300 0 0
rRNA processing R-HSA-72312 3.103178e-01 0.508 0 0
Regulated Necrosis R-HSA-5218859 4.401388e-01 0.356 0 0
FLT3 Signaling R-HSA-9607240 3.172880e-01 0.499 0 0
Hemostasis R-HSA-109582 5.484366e-01 0.261 0 0
Smooth Muscle Contraction R-HSA-445355 3.050826e-01 0.516 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 2.187113e-01 0.660 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 4.335355e-01 0.363 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 4.777700e-01 0.321 0 0
TBC/RABGAPs R-HSA-8854214 5.255703e-01 0.279 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 4.627490e-01 0.335 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 4.887828e-01 0.311 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.049665e-01 0.297 0 0
Negative regulation of FLT3 R-HSA-9706369 5.016282e-01 0.300 0 0
Amine ligand-binding receptors R-HSA-375280 5.458402e-01 0.263 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.569097e-01 0.447 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 4.249148e-01 0.372 0 0
Stimuli-sensing channels R-HSA-2672351 4.421506e-01 0.354 0 0
Nef and signal transduction R-HSA-164944 3.396010e-01 0.469 0 0
Lipid particle organization R-HSA-8964572 3.396010e-01 0.469 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 4.777700e-01 0.321 0 0
Interleukin-1 processing R-HSA-448706 4.777700e-01 0.321 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 4.777700e-01 0.321 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 4.680725e-01 0.330 0 0
SARS-CoV-2-host interactions R-HSA-9705683 4.702839e-01 0.328 0 0
Sensory processing of sound R-HSA-9659379 1.975019e-01 0.704 0 0
Ion transport by P-type ATPases R-HSA-936837 4.976341e-01 0.303 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 2.858680e-01 0.544 0 0
PI Metabolism R-HSA-1483255 4.466467e-01 0.350 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 2.907490e-01 0.536 0 0
DSCAM interactions R-HSA-376172 4.149838e-01 0.382 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 2.539176e-01 0.595 0 0
Platelet sensitization by LDL R-HSA-432142 1.986340e-01 0.702 0 0
Synthesis of PI R-HSA-1483226 2.898366e-01 0.538 0 0
CASP5-mediated substrate cleavage R-HSA-9960525 4.883761e-01 0.311 0 0
SLC-mediated bile acid transport R-HSA-9958517 4.335355e-01 0.363 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 2.714831e-01 0.566 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 5.525648e-01 0.258 0 0
Eicosanoid ligand-binding receptors R-HSA-391903 4.308085e-01 0.366 0 0
Amyloid fiber formation R-HSA-977225 3.104790e-01 0.508 0 0
LTC4-CYSLTR mediated IL4 production R-HSA-9664535 5.198249e-01 0.284 0 0
Activation of SMO R-HSA-5635838 5.016282e-01 0.300 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.365625e-01 0.360 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.505504e-01 0.346 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 5.595509e-01 0.252 0 0
Signaling by TGFB family members R-HSA-9006936 5.156708e-01 0.288 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.221908e-01 0.653 0 0
Plasma lipoprotein assembly R-HSA-8963898 2.179176e-01 0.662 0 0
Signal regulatory protein family interactions R-HSA-391160 4.335411e-01 0.363 0 0
Basigin interactions R-HSA-210991 4.600646e-01 0.337 0 0
SARS-CoV-1-host interactions R-HSA-9692914 2.416991e-01 0.617 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.907490e-01 0.536 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.522932e-01 0.598 0 0
Histamine receptors R-HSA-390650 4.883761e-01 0.311 0 0
PECAM1 interactions R-HSA-210990 5.595509e-01 0.252 0 0
Unfolded Protein Response (UPR) R-HSA-381119 5.212341e-01 0.283 0 0
Miscellaneous transport and binding events R-HSA-5223345 2.920741e-01 0.535 0 0
Syndecan interactions R-HSA-3000170 3.489530e-01 0.457 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 4.531906e-01 0.344 0 0
Co-stimulation by CD28 R-HSA-389356 4.761769e-01 0.322 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 3.569097e-01 0.447 0 0
NrCAM interactions R-HSA-447038 2.414743e-01 0.617 0 0
Growth hormone receptor signaling R-HSA-982772 1.972174e-01 0.705 0 0
Phase 3 - rapid repolarisation R-HSA-5576890 3.873613e-01 0.412 0 0
CASP4-mediated substrate cleavage R-HSA-9960519 4.883761e-01 0.311 0 0
Regulation of MITF-M dependent genes involved in metabolism R-HSA-9854907 4.883761e-01 0.311 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.970091e-01 0.527 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 3.172880e-01 0.499 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 5.525648e-01 0.258 0 0
Signaling by Interleukins R-HSA-449147 1.910551e-01 0.719 0 0
HDL assembly R-HSA-8963896 2.237664e-01 0.650 0 0
IRE1alpha activates chaperones R-HSA-381070 4.857718e-01 0.314 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 4.149838e-01 0.382 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 3.020721e-01 0.520 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 4.680725e-01 0.330 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 2.815138e-01 0.551 0 0
Signaling by Leptin R-HSA-2586552 2.539176e-01 0.595 0 0
Selenoamino acid metabolism R-HSA-2408522 3.984347e-01 0.400 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 3.982136e-01 0.400 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.479685e-01 0.349 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 5.652687e-01 0.248 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 4.335411e-01 0.363 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 5.706840e-01 0.244 0 0
Signaling by NOTCH1 R-HSA-1980143 5.707951e-01 0.244 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 5.714583e-01 0.243 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 5.740948e-01 0.241 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.744778e-01 0.241 0 0
Inwardly rectifying K+ channels R-HSA-1296065 5.758012e-01 0.240 0 0
Signaling by WNT in cancer R-HSA-4791275 5.758012e-01 0.240 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 5.758012e-01 0.240 0 0
Aquaporin-mediated transport R-HSA-445717 5.767399e-01 0.239 0 0
Signaling by ALK R-HSA-201556 5.806381e-01 0.236 0 0
Interferon Signaling R-HSA-913531 5.812282e-01 0.236 0 0
Regulation of TNFR1 signaling R-HSA-5357905 5.852227e-01 0.233 0 0
Interferon gamma signaling R-HSA-877300 5.870519e-01 0.231 0 0
Inositol phosphate metabolism R-HSA-1483249 5.937312e-01 0.226 0 0
Heme signaling R-HSA-9707616 5.937449e-01 0.226 0 0
Interleukin-1 family signaling R-HSA-446652 5.939480e-01 0.226 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 5.947035e-01 0.226 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 5.951582e-01 0.225 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 5.951582e-01 0.225 0 0
Mismatch Repair R-HSA-5358508 5.951582e-01 0.225 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 5.951582e-01 0.225 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 5.951582e-01 0.225 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 5.951582e-01 0.225 0 0
Interleukin-7 signaling R-HSA-1266695 5.963034e-01 0.225 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 5.968705e-01 0.224 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 5.968705e-01 0.224 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 5.968705e-01 0.224 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 5.968705e-01 0.224 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 5.968705e-01 0.224 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 5.977295e-01 0.223 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.977295e-01 0.223 0 0
G-protein beta:gamma signalling R-HSA-397795 5.985570e-01 0.223 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 5.985570e-01 0.223 0 0
HIV Infection R-HSA-162906 6.002765e-01 0.222 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 6.013006e-01 0.221 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 6.013006e-01 0.221 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 6.013006e-01 0.221 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 6.013006e-01 0.221 0 0
Glycogen metabolism R-HSA-8982491 6.013006e-01 0.221 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 6.026704e-01 0.220 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 6.042679e-01 0.219 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 6.052387e-01 0.218 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 6.073295e-01 0.217 0 0
Activation of AMPA receptors R-HSA-399710 6.087036e-01 0.216 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 6.087036e-01 0.216 0 0
NOSIP mediated eNOS trafficking R-HSA-203754 6.087036e-01 0.216 0 0
Defective SLC1A3 causes episodic ataxia 6 (EA6) R-HSA-5619062 6.087036e-01 0.216 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 6.087036e-01 0.216 0 0
Post-transcriptional silencing by small RNAs R-HSA-426496 6.087036e-01 0.216 0 0
PTK6 Down-Regulation R-HSA-8849472 6.087036e-01 0.216 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 6.087036e-01 0.216 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 6.087036e-01 0.216 0 0
Muscarinic acetylcholine receptors R-HSA-390648 6.087036e-01 0.216 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 6.087036e-01 0.216 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 6.087036e-01 0.216 0 0
Co-inhibition by BTLA R-HSA-9927353 6.087036e-01 0.216 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 6.087036e-01 0.216 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 6.087036e-01 0.216 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 6.104175e-01 0.214 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 6.118886e-01 0.213 0 0
XBP1(S) activates chaperone genes R-HSA-381038 6.195442e-01 0.208 0 0
Effects of PIP2 hydrolysis R-HSA-114508 6.206084e-01 0.207 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 6.206084e-01 0.207 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 6.209868e-01 0.207 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 6.209868e-01 0.207 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.236748e-01 0.205 0 0
Germ layer formation at gastrulation R-HSA-9754189 6.236748e-01 0.205 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.236748e-01 0.205 0 0
PPARA activates gene expression R-HSA-1989781 6.260180e-01 0.203 0 0
p75NTR recruits signalling complexes R-HSA-209543 6.317621e-01 0.199 0 0
Scavenging by Class F Receptors R-HSA-3000484 6.317621e-01 0.199 0 0
VLDLR internalisation and degradation R-HSA-8866427 6.317621e-01 0.199 0 0
Interleukin-15 signaling R-HSA-8983432 6.317621e-01 0.199 0 0
OAS antiviral response R-HSA-8983711 6.317621e-01 0.199 0 0
Regulation of IFNG signaling R-HSA-877312 6.317621e-01 0.199 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 6.317621e-01 0.199 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 6.407295e-01 0.193 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 6.409274e-01 0.193 0 0
Degradation of CDH1 R-HSA-9766229 6.409274e-01 0.193 0 0
Regulation of CDH1 Function R-HSA-9764561 6.415950e-01 0.193 0 0
Mitophagy R-HSA-5205647 6.419223e-01 0.193 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 6.431005e-01 0.192 0 0
Cristae formation R-HSA-8949613 6.446962e-01 0.191 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 6.456481e-01 0.190 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 6.467420e-01 0.189 0 0
HCMV Late Events R-HSA-9610379 6.467420e-01 0.189 0 0
Signal transduction by L1 R-HSA-445144 6.507830e-01 0.187 0 0
Formation of definitive endoderm R-HSA-9823730 6.507830e-01 0.187 0 0
Protein hydroxylation R-HSA-9629569 6.507830e-01 0.187 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 6.523919e-01 0.185 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 6.529969e-01 0.185 0 0
Plus-strand DNA synthesis R-HSA-164525 6.578017e-01 0.182 0 0
Nef Mediated CD8 Down-regulation R-HSA-182218 6.578017e-01 0.182 0 0
PKB-mediated events R-HSA-109703 6.578017e-01 0.182 0 0
PDE3B signalling R-HSA-165160 6.578017e-01 0.182 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 6.578017e-01 0.182 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 6.578017e-01 0.182 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 6.578017e-01 0.182 0 0
IkBA variant leads to EDA-ID R-HSA-5603029 6.578017e-01 0.182 0 0
Signaling by MAPK mutants R-HSA-9652817 6.578017e-01 0.182 0 0
Phase 1 - inactivation of fast Na+ channels R-HSA-5576894 6.578017e-01 0.182 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 6.578017e-01 0.182 0 0
Ceramide signalling R-HSA-193681 6.578017e-01 0.182 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 6.578017e-01 0.182 0 0
SLIT2:ROBO1 increases RHOA activity R-HSA-8985586 6.578017e-01 0.182 0 0
Synthesis of PS R-HSA-1483101 6.578017e-01 0.182 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 6.578017e-01 0.182 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 6.578017e-01 0.182 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 6.578017e-01 0.182 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 6.578017e-01 0.182 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 6.578017e-01 0.182 0 0
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660825 6.578017e-01 0.182 0 0
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant R-HSA-2660826 6.578017e-01 0.182 0 0
RUNX3 regulates CDKN1A transcription R-HSA-8941855 6.578017e-01 0.182 0 0
Signaling by ERBB4 R-HSA-1236394 6.588476e-01 0.181 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 6.642475e-01 0.178 0 0
Adenylate cyclase activating pathway R-HSA-170660 6.642475e-01 0.178 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 6.642475e-01 0.178 0 0
FGFR1c ligand binding and activation R-HSA-190373 6.642475e-01 0.178 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 6.642475e-01 0.178 0 0
Reversible hydration of carbon dioxide R-HSA-1475029 6.642475e-01 0.178 0 0
Maturation of nucleoprotein R-HSA-9683610 6.642475e-01 0.178 0 0
Ion channel transport R-HSA-983712 6.655658e-01 0.177 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 6.674054e-01 0.176 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 6.674054e-01 0.176 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 6.732716e-01 0.172 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 6.732716e-01 0.172 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.748317e-01 0.171 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.764661e-01 0.170 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 6.764661e-01 0.170 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.764661e-01 0.170 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 6.764661e-01 0.170 0 0
ERK/MAPK targets R-HSA-198753 6.764661e-01 0.170 0 0
Mitochondrial biogenesis R-HSA-1592230 6.780400e-01 0.169 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 6.822417e-01 0.166 0 0
RNA Polymerase III Transcription R-HSA-74158 6.822417e-01 0.166 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 6.822417e-01 0.166 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 6.890982e-01 0.162 0 0
DARPP-32 events R-HSA-180024 6.890982e-01 0.162 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 6.896617e-01 0.161 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 6.896617e-01 0.161 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 6.896617e-01 0.161 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 6.896617e-01 0.161 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 6.896617e-01 0.161 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 6.920365e-01 0.160 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 6.920365e-01 0.160 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 6.925372e-01 0.160 0 0
Prolactin receptor signaling R-HSA-1170546 6.943811e-01 0.158 0 0
Regulation of CDH1 mRNA translation by microRNAs R-HSA-9764562 6.943811e-01 0.158 0 0
Retrograde neurotrophin signalling R-HSA-177504 6.943811e-01 0.158 0 0
cGMP effects R-HSA-418457 6.943811e-01 0.158 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 6.943811e-01 0.158 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 6.943811e-01 0.158 0 0
Zinc transporters R-HSA-435354 6.943811e-01 0.158 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 6.997633e-01 0.155 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.002343e-01 0.155 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.002343e-01 0.155 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 7.007242e-01 0.154 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 7.007242e-01 0.154 0 0
Signaling by PDGFR in disease R-HSA-9671555 7.007242e-01 0.154 0 0
Signaling by LTK in cancer R-HSA-9842640 7.007416e-01 0.154 0 0
STAT5 Activation R-HSA-9645135 7.007416e-01 0.154 0 0
Erythropoietin activates STAT5 R-HSA-9027283 7.007416e-01 0.154 0 0
Uncoating of the HIV Virion R-HSA-162585 7.007416e-01 0.154 0 0
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors R-HSA-629587 7.007416e-01 0.154 0 0
Autointegration results in viral DNA circles R-HSA-177539 7.007416e-01 0.154 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 7.007416e-01 0.154 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 7.007416e-01 0.154 0 0
Abacavir transmembrane transport R-HSA-2161517 7.007416e-01 0.154 0 0
NADPH regeneration R-HSA-389542 7.007416e-01 0.154 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 7.007416e-01 0.154 0 0
HDL clearance R-HSA-8964011 7.007416e-01 0.154 0 0
VLDL assembly R-HSA-8866423 7.007416e-01 0.154 0 0
MAP kinase activation R-HSA-450294 7.047439e-01 0.152 0 0
Viral Messenger RNA Synthesis R-HSA-168325 7.047439e-01 0.152 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 7.079820e-01 0.150 0 0
DAP12 signaling R-HSA-2424491 7.097677e-01 0.149 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.097677e-01 0.149 0 0
Adaptive Immune System R-HSA-1280218 7.099207e-01 0.149 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 7.122941e-01 0.147 0 0
Macroautophagy R-HSA-1632852 7.122941e-01 0.147 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 7.124159e-01 0.147 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 7.126390e-01 0.147 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 7.129524e-01 0.147 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 7.193887e-01 0.143 0 0
MET promotes cell motility R-HSA-8875878 7.193887e-01 0.143 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 7.193887e-01 0.143 0 0
Cellular response to heat stress R-HSA-3371556 7.215015e-01 0.142 0 0
Erythropoietin activates RAS R-HSA-9027284 7.222414e-01 0.141 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 7.222414e-01 0.141 0 0
SHC1 events in EGFR signaling R-HSA-180336 7.222414e-01 0.141 0 0
G beta:gamma signalling through BTK R-HSA-8964315 7.222414e-01 0.141 0 0
p75NTR signals via NF-kB R-HSA-193639 7.222414e-01 0.141 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 7.222414e-01 0.141 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 7.222414e-01 0.141 0 0
Biotin transport and metabolism R-HSA-196780 7.222414e-01 0.141 0 0
Spry regulation of FGF signaling R-HSA-1295596 7.222414e-01 0.141 0 0
Protein methylation R-HSA-8876725 7.222414e-01 0.141 0 0
FGFR2 alternative splicing R-HSA-6803529 7.235708e-01 0.141 0 0
Notch-HLH transcription pathway R-HSA-350054 7.235708e-01 0.141 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 7.235708e-01 0.141 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 7.289386e-01 0.137 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.317778e-01 0.136 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.317778e-01 0.136 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 7.367590e-01 0.133 0 0
Vesicle-mediated transport R-HSA-5653656 7.369573e-01 0.133 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 7.382955e-01 0.132 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 7.382955e-01 0.132 0 0
CHL1 interactions R-HSA-447041 7.382955e-01 0.132 0 0
Defective HLCS causes multiple carboxylase deficiency R-HSA-3371599 7.382955e-01 0.132 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 7.382955e-01 0.132 0 0
Regulation of PTEN localization R-HSA-8948747 7.382955e-01 0.132 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 7.382955e-01 0.132 0 0
TRIF-mediated programmed cell death R-HSA-2562578 7.382955e-01 0.132 0 0
FGFR3b ligand binding and activation R-HSA-190371 7.382955e-01 0.132 0 0
Disinhibition of SNARE formation R-HSA-114516 7.382955e-01 0.132 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 7.382955e-01 0.132 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 7.382955e-01 0.132 0 0
Cysteine formation from homocysteine R-HSA-1614603 7.382955e-01 0.132 0 0
LDL remodeling R-HSA-8964041 7.382955e-01 0.132 0 0
Ca2+ activated K+ channels R-HSA-1296052 7.382955e-01 0.132 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 7.382955e-01 0.132 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 7.382955e-01 0.132 0 0
PKR-mediated signaling R-HSA-9833482 7.397665e-01 0.131 0 0
Clathrin-mediated endocytosis R-HSA-8856828 7.407713e-01 0.130 0 0
Formation of the ureteric bud R-HSA-9830674 7.450311e-01 0.128 0 0
Insulin receptor signalling cascade R-HSA-74751 7.470668e-01 0.127 0 0
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion R-HSA-434316 7.479246e-01 0.126 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 7.479246e-01 0.126 0 0
Class I peroxisomal membrane protein import R-HSA-9603798 7.479246e-01 0.126 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 7.479246e-01 0.126 0 0
Regulation of BACH1 activity R-HSA-9708530 7.479246e-01 0.126 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 7.479246e-01 0.126 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 7.480490e-01 0.126 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 7.524482e-01 0.124 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 7.533299e-01 0.123 0 0
Diseases of Immune System R-HSA-5260271 7.533299e-01 0.123 0 0
Co-inhibition by PD-1 R-HSA-389948 7.582356e-01 0.120 0 0
Metal ion SLC transporters R-HSA-425410 7.595523e-01 0.119 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 7.651392e-01 0.116 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.651392e-01 0.116 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 7.656836e-01 0.116 0 0
Regulation of necroptotic cell death R-HSA-5675482 7.656836e-01 0.116 0 0
Reverse Transcription of HIV RNA R-HSA-162589 7.711387e-01 0.113 0 0
Minus-strand DNA synthesis R-HSA-164516 7.711387e-01 0.113 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 7.711387e-01 0.113 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 7.711387e-01 0.113 0 0
phospho-PLA2 pathway R-HSA-111995 7.711387e-01 0.113 0 0
Regulation of NPAS4 mRNA translation R-HSA-9768778 7.711387e-01 0.113 0 0
Highly calcium permeable nicotinic acetylcholine receptors R-HSA-629597 7.711387e-01 0.113 0 0
Formation of annular gap junctions R-HSA-196025 7.711387e-01 0.113 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 7.711387e-01 0.113 0 0
Interleukin-9 signaling R-HSA-8985947 7.711387e-01 0.113 0 0
Regulation by c-FLIP R-HSA-3371378 7.711387e-01 0.113 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 7.711387e-01 0.113 0 0
Dimerization of procaspase-8 R-HSA-69416 7.711387e-01 0.113 0 0
TGFBR3 PTM regulation R-HSA-9839383 7.711387e-01 0.113 0 0
Alpha-defensins R-HSA-1462054 7.711387e-01 0.113 0 0
Interleukin-23 signaling R-HSA-9020933 7.711387e-01 0.113 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 7.715381e-01 0.113 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 7.715381e-01 0.113 0 0
Phase 2 - plateau phase R-HSA-5576893 7.715381e-01 0.113 0 0
Synthesis of PG R-HSA-1483148 7.715381e-01 0.113 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 7.738725e-01 0.111 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 7.738725e-01 0.111 0 0
Protein ubiquitination R-HSA-8852135 7.794477e-01 0.108 0 0
HCMV Infection R-HSA-9609646 7.808460e-01 0.107 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 7.823387e-01 0.107 0 0
Autophagy R-HSA-9612973 7.831506e-01 0.106 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.839371e-01 0.106 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.839371e-01 0.106 0 0
G protein gated Potassium channels R-HSA-1296059 7.839371e-01 0.106 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.839371e-01 0.106 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 7.839371e-01 0.106 0 0
Formation of the nephric duct R-HSA-9830364 7.839371e-01 0.106 0 0
Intra-Golgi traffic R-HSA-6811438 7.841068e-01 0.106 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 7.841068e-01 0.106 0 0
SLC-mediated transport of neurotransmitters R-HSA-442660 7.841068e-01 0.106 0 0
PI3K Cascade R-HSA-109704 7.875436e-01 0.104 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 7.931968e-01 0.101 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 7.931968e-01 0.101 0 0
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) R-HSA-5358606 7.931968e-01 0.101 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 7.931968e-01 0.101 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 7.931968e-01 0.101 0 0
Synthesis of PIPs at the late endosome membrane R-HSA-1660517 7.931968e-01 0.101 0 0
Transcription of the HIV genome R-HSA-167172 7.966192e-01 0.099 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 7.980383e-01 0.098 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 7.980383e-01 0.098 0 0
NOD1/2 Signaling Pathway R-HSA-168638 7.980383e-01 0.098 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 7.998618e-01 0.097 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 7.998618e-01 0.097 0 0
Regulated proteolysis of p75NTR R-HSA-193692 7.998618e-01 0.097 0 0
CASP8 activity is inhibited R-HSA-5218900 7.998618e-01 0.097 0 0
Defects in biotin (Btn) metabolism R-HSA-3323169 7.998618e-01 0.097 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 7.998618e-01 0.097 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 7.998618e-01 0.097 0 0
Regulation of signaling by NODAL R-HSA-1433617 7.998618e-01 0.097 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 7.998618e-01 0.097 0 0
Lipophagy R-HSA-9613354 7.998618e-01 0.097 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 7.998618e-01 0.097 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 7.998618e-01 0.097 0 0
The phototransduction cascade R-HSA-2514856 8.005752e-01 0.097 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 8.014721e-01 0.096 0 0
SARS-CoV-2 Infection R-HSA-9694516 8.024155e-01 0.096 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 8.101088e-01 0.091 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.117643e-01 0.091 0 0
Signaling by FGFR4 R-HSA-5654743 8.118202e-01 0.091 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 8.128101e-01 0.090 0 0
Cytosolic iron-sulfur cluster assembly R-HSA-2564830 8.130194e-01 0.090 0 0
G beta:gamma signalling through PLC beta R-HSA-418217 8.130194e-01 0.090 0 0
FGFR1 ligand binding and activation R-HSA-190242 8.130194e-01 0.090 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 8.130194e-01 0.090 0 0
Presynaptic function of Kainate receptors R-HSA-500657 8.130194e-01 0.090 0 0
Chaperone Mediated Autophagy R-HSA-9613829 8.130194e-01 0.090 0 0
Apoptotic factor-mediated response R-HSA-111471 8.130194e-01 0.090 0 0
Tie2 Signaling R-HSA-210993 8.130194e-01 0.090 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 8.130194e-01 0.090 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 8.153721e-01 0.089 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 8.177959e-01 0.087 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 8.177959e-01 0.087 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 8.177959e-01 0.087 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 8.177959e-01 0.087 0 0
Insulin processing R-HSA-264876 8.177959e-01 0.087 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 8.177959e-01 0.087 0 0
Signaling by NOTCH R-HSA-157118 8.182456e-01 0.087 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 8.184989e-01 0.087 0 0
Interleukin-17 signaling R-HSA-448424 8.184989e-01 0.087 0 0
DAP12 interactions R-HSA-2172127 8.245719e-01 0.084 0 0
DNA replication initiation R-HSA-68952 8.249815e-01 0.084 0 0
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors R-HSA-629594 8.249815e-01 0.084 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 8.249815e-01 0.084 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 8.249815e-01 0.084 0 0
Maturation of spike protein R-HSA-9683686 8.249815e-01 0.084 0 0
MAPK3 (ERK1) activation R-HSA-110056 8.249815e-01 0.084 0 0
Metal sequestration by antimicrobial proteins R-HSA-6799990 8.249815e-01 0.084 0 0
Josephin domain DUBs R-HSA-5689877 8.249815e-01 0.084 0 0
Tandem pore domain potassium channels R-HSA-1296346 8.249815e-01 0.084 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 8.249815e-01 0.084 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 8.255019e-01 0.083 0 0
Signaling by PDGF R-HSA-186797 8.263322e-01 0.083 0 0
Triglyceride catabolism R-HSA-163560 8.266846e-01 0.083 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 8.311255e-01 0.080 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 8.311255e-01 0.080 0 0
Other interleukin signaling R-HSA-449836 8.311255e-01 0.080 0 0
Maturation of nucleoprotein R-HSA-9694631 8.311255e-01 0.080 0 0
HIV elongation arrest and recovery R-HSA-167287 8.329634e-01 0.079 0 0
Pausing and recovery of HIV elongation R-HSA-167290 8.329634e-01 0.079 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 8.329634e-01 0.079 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 8.329634e-01 0.079 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 8.329634e-01 0.079 0 0
PTEN Regulation R-HSA-6807070 8.334131e-01 0.079 0 0
Signaling by FGFR3 R-HSA-5654741 8.366147e-01 0.077 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 8.366147e-01 0.077 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 8.385197e-01 0.076 0 0
Leishmania phagocytosis R-HSA-9664417 8.404077e-01 0.076 0 0
Parasite infection R-HSA-9664407 8.404077e-01 0.076 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 8.404077e-01 0.076 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 8.419773e-01 0.075 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 8.430198e-01 0.074 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 8.465658e-01 0.072 0 0
Regulation of CDH11 mRNA translation by microRNAs R-HSA-9759811 8.469496e-01 0.072 0 0
Presynaptic depolarization and calcium channel opening R-HSA-112308 8.469496e-01 0.072 0 0
LGI-ADAM interactions R-HSA-5682910 8.469496e-01 0.072 0 0
FGFR2b ligand binding and activation R-HSA-190377 8.469496e-01 0.072 0 0
vRNA Synthesis R-HSA-192814 8.469496e-01 0.072 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 8.469496e-01 0.072 0 0
Transport of RCbl within the body R-HSA-9758890 8.469496e-01 0.072 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 8.469496e-01 0.072 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 8.469496e-01 0.072 0 0
Suppression of apoptosis R-HSA-9635465 8.469496e-01 0.072 0 0
Prostanoid ligand receptors R-HSA-391908 8.469496e-01 0.072 0 0
Signaling by Erythropoietin R-HSA-9006335 8.470311e-01 0.072 0 0
Late endosomal microautophagy R-HSA-9615710 8.470311e-01 0.072 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 8.470311e-01 0.072 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 8.470311e-01 0.072 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 8.470311e-01 0.072 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 8.476337e-01 0.072 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 8.476337e-01 0.072 0 0
Signaling by NODAL R-HSA-1181150 8.476337e-01 0.072 0 0
Negative regulation of MET activity R-HSA-6807004 8.476337e-01 0.072 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 8.479714e-01 0.072 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 8.518742e-01 0.070 0 0
Platelet degranulation R-HSA-114608 8.529056e-01 0.069 0 0
Signaling by FGFR1 R-HSA-5654736 8.566075e-01 0.067 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 8.566075e-01 0.067 0 0
Signaling by FGFR in disease R-HSA-1226099 8.567568e-01 0.067 0 0
MITF-M-dependent gene expression R-HSA-9856651 8.575031e-01 0.067 0 0
Potential therapeutics for SARS R-HSA-9679191 8.575031e-01 0.067 0 0
Toll-like Receptor Cascades R-HSA-168898 8.592941e-01 0.066 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 8.600569e-01 0.065 0 0
G-protein activation R-HSA-202040 8.626596e-01 0.064 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 8.626596e-01 0.064 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 8.626596e-01 0.064 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 8.626596e-01 0.064 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 8.626596e-01 0.064 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 8.626596e-01 0.064 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 8.632595e-01 0.064 0 0
Stabilization of p53 R-HSA-69541 8.632595e-01 0.064 0 0
IRS-mediated signalling R-HSA-112399 8.661019e-01 0.062 0 0
Presynaptic nicotinic acetylcholine receptors R-HSA-622323 8.661615e-01 0.062 0 0
Endosomal/Vacuolar pathway R-HSA-1236977 8.661615e-01 0.062 0 0
Signaling by activated point mutants of FGFR1 R-HSA-1839122 8.661615e-01 0.062 0 0
NF-kB is activated and signals survival R-HSA-209560 8.661615e-01 0.062 0 0
Plasmalogen biosynthesis R-HSA-75896 8.661615e-01 0.062 0 0
ERKs are inactivated R-HSA-202670 8.661615e-01 0.062 0 0
Sodium/Calcium exchangers R-HSA-425561 8.661615e-01 0.062 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 8.661615e-01 0.062 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.672688e-01 0.062 0 0
Gluconeogenesis R-HSA-70263 8.687234e-01 0.061 0 0
SARS-CoV Infections R-HSA-9679506 8.705144e-01 0.060 0 0
Budding and maturation of HIV virion R-HSA-162588 8.720986e-01 0.059 0 0
Cargo concentration in the ER R-HSA-5694530 8.720986e-01 0.059 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 8.738865e-01 0.059 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 8.738865e-01 0.059 0 0
HIV Transcription Elongation R-HSA-167169 8.738865e-01 0.059 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 8.738865e-01 0.059 0 0
Generation of second messenger molecules R-HSA-202433 8.738865e-01 0.059 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 8.763154e-01 0.057 0 0
Mitochondrial calcium ion transport R-HSA-8949215 8.763154e-01 0.057 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 8.763154e-01 0.057 0 0
Assembly Of The HIV Virion R-HSA-175474 8.763154e-01 0.057 0 0
Gap junction trafficking and regulation R-HSA-157858 8.781694e-01 0.056 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 8.781694e-01 0.056 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 8.809622e-01 0.055 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 8.829627e-01 0.054 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 8.829627e-01 0.054 0 0
IRAK1 recruits IKK complex R-HSA-937039 8.829627e-01 0.054 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 8.829627e-01 0.054 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 8.829627e-01 0.054 0 0
GRB2 events in EGFR signaling R-HSA-179812 8.829627e-01 0.054 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 8.829627e-01 0.054 0 0
Serotonin clearance from the synaptic cleft R-HSA-380615 8.829627e-01 0.054 0 0
MET activates RAS signaling R-HSA-8851805 8.829627e-01 0.054 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 8.829627e-01 0.054 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 8.829627e-01 0.054 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 8.829627e-01 0.054 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 8.829627e-01 0.054 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 8.829627e-01 0.054 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 8.829627e-01 0.054 0 0
Estrogen biosynthesis R-HSA-193144 8.829627e-01 0.054 0 0
Triglyceride metabolism R-HSA-8979227 8.835254e-01 0.054 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 8.849208e-01 0.053 0 0
Viral Infection Pathways R-HSA-9824446 8.860803e-01 0.053 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 8.880057e-01 0.052 0 0
PCP/CE pathway R-HSA-4086400 8.882392e-01 0.051 0 0
ER to Golgi Anterograde Transport R-HSA-199977 8.886124e-01 0.051 0 0
Signaling by KIT in disease R-HSA-9669938 8.887080e-01 0.051 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 8.887080e-01 0.051 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 8.887080e-01 0.051 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 8.887080e-01 0.051 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 8.887080e-01 0.051 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 8.887080e-01 0.051 0 0
LDL clearance R-HSA-8964038 8.887080e-01 0.051 0 0
Circadian clock R-HSA-9909396 8.896302e-01 0.051 0 0
HIV Transcription Initiation R-HSA-167161 8.930125e-01 0.049 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.930125e-01 0.049 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.930125e-01 0.049 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 8.934591e-01 0.049 0 0
Cardiogenesis R-HSA-9733709 8.934591e-01 0.049 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 8.946973e-01 0.048 0 0
Acetylcholine binding and downstream events R-HSA-181431 8.976557e-01 0.047 0 0
Postsynaptic nicotinic acetylcholine receptors R-HSA-622327 8.976557e-01 0.047 0 0
FGFR2c ligand binding and activation R-HSA-190375 8.976557e-01 0.047 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 8.976557e-01 0.047 0 0
FGFR4 ligand binding and activation R-HSA-190322 8.976557e-01 0.047 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 8.976557e-01 0.047 0 0
Signaling by activated point mutants of FGFR3 R-HSA-1839130 8.976557e-01 0.047 0 0
Mtb iron assimilation by chelation R-HSA-1222449 8.976557e-01 0.047 0 0
Formation of axial mesoderm R-HSA-9796292 8.976557e-01 0.047 0 0
FGFR3 mutant receptor activation R-HSA-2033514 8.976557e-01 0.047 0 0
CD28 dependent Vav1 pathway R-HSA-389359 8.976557e-01 0.047 0 0
Acyl chain remodeling of DAG and TAG R-HSA-1482883 8.976557e-01 0.047 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 8.999394e-01 0.046 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 8.999394e-01 0.046 0 0
Free fatty acids regulate insulin secretion R-HSA-400451 8.999394e-01 0.046 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 9.015845e-01 0.045 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.015845e-01 0.045 0 0
Signaling by FGFR2 R-HSA-5654738 9.016828e-01 0.045 0 0
Signaling by MET R-HSA-6806834 9.016828e-01 0.045 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 9.028897e-01 0.044 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 9.030989e-01 0.044 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 9.060431e-01 0.043 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 9.064603e-01 0.043 0 0
RSV-host interactions R-HSA-9833110 9.065341e-01 0.043 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 9.079262e-01 0.042 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 9.095437e-01 0.041 0 0
Thromboxane signalling through TP receptor R-HSA-428930 9.101058e-01 0.041 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 9.103595e-01 0.041 0 0
Phospholipase C-mediated cascade; FGFR3 R-HSA-5654227 9.105048e-01 0.041 0 0
CRMPs in Sema3A signaling R-HSA-399956 9.105048e-01 0.041 0 0
NRIF signals cell death from the nucleus R-HSA-205043 9.105048e-01 0.041 0 0
FGFR3c ligand binding and activation R-HSA-190372 9.105048e-01 0.041 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 9.105048e-01 0.041 0 0
Hydrolysis of LPC R-HSA-1483115 9.105048e-01 0.041 0 0
Physiological factors R-HSA-5578768 9.105048e-01 0.041 0 0
Malate-aspartate shuttle R-HSA-9856872 9.105048e-01 0.041 0 0
Non-canonical inflammasome activation R-HSA-9686114 9.105048e-01 0.041 0 0
Acyl chain remodeling of CL R-HSA-1482798 9.105048e-01 0.041 0 0
P2Y receptors R-HSA-417957 9.105048e-01 0.041 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 9.115593e-01 0.040 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 9.115593e-01 0.040 0 0
Hyaluronan metabolism R-HSA-2142845 9.115593e-01 0.040 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.123008e-01 0.040 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 9.192974e-01 0.037 0 0
Laminin interactions R-HSA-3000157 9.192974e-01 0.037 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 9.195194e-01 0.036 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 9.195194e-01 0.036 0 0
Synthesis of DNA R-HSA-69239 9.215599e-01 0.035 0 0
Competing endogenous RNAs (ceRNAs) regulate PTEN translation R-HSA-8948700 9.217414e-01 0.035 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 9.217414e-01 0.035 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 9.217414e-01 0.035 0 0
Phospholipase C-mediated cascade; FGFR4 R-HSA-5654228 9.217414e-01 0.035 0 0
FGFR3 ligand binding and activation R-HSA-190239 9.217414e-01 0.035 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 9.217414e-01 0.035 0 0
Synthesis of 12-eicosatetraenoic acid derivatives R-HSA-2142712 9.217414e-01 0.035 0 0
Dopamine clearance from the synaptic cleft R-HSA-379401 9.217414e-01 0.035 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 9.217414e-01 0.035 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 9.217414e-01 0.035 0 0
Other semaphorin interactions R-HSA-416700 9.217414e-01 0.035 0 0
Formation of the anterior neural plate R-HSA-9823739 9.217414e-01 0.035 0 0
Signaling by Hedgehog R-HSA-5358351 9.227344e-01 0.035 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 9.237632e-01 0.034 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 9.237632e-01 0.034 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 9.237632e-01 0.034 0 0
Cellular response to hypoxia R-HSA-1234174 9.246984e-01 0.034 0 0
Hedgehog 'off' state R-HSA-5610787 9.266955e-01 0.033 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 9.268149e-01 0.033 0 0
Glycosphingolipid transport R-HSA-9845576 9.268196e-01 0.033 0 0
RUNX2 regulates bone development R-HSA-8941326 9.268196e-01 0.033 0 0
Signaling by EGFR in Cancer R-HSA-1643713 9.275988e-01 0.033 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 9.275988e-01 0.033 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 9.275988e-01 0.033 0 0
Signaling by Insulin receptor R-HSA-74752 9.277671e-01 0.033 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.277671e-01 0.033 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 9.299378e-01 0.032 0 0
Leishmania parasite growth and survival R-HSA-9664433 9.299378e-01 0.032 0 0
Interleukin-1 signaling R-HSA-9020702 9.311248e-01 0.031 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 9.315678e-01 0.031 0 0
Activation of the phototransduction cascade R-HSA-2485179 9.315678e-01 0.031 0 0
Differentiation of T cells R-HSA-9945266 9.315678e-01 0.031 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 9.315678e-01 0.031 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 9.315678e-01 0.031 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 9.315678e-01 0.031 0 0
Fructose catabolism R-HSA-70350 9.315678e-01 0.031 0 0
Attachment and Entry R-HSA-9678110 9.315678e-01 0.031 0 0
Atorvastatin ADME R-HSA-9754706 9.315678e-01 0.031 0 0
Degradation of DVL R-HSA-4641258 9.335071e-01 0.030 0 0
Synthesis of PA R-HSA-1483166 9.348357e-01 0.029 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 9.350885e-01 0.029 0 0
Triglyceride biosynthesis R-HSA-75109 9.350885e-01 0.029 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 9.350885e-01 0.029 0 0
Synthesis of PC R-HSA-1483191 9.359394e-01 0.029 0 0
Immune System R-HSA-168256 9.372400e-01 0.028 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.399345e-01 0.027 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 9.401608e-01 0.027 0 0
Vitamin B6 activation to pyridoxal phosphate R-HSA-964975 9.401608e-01 0.027 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 9.401608e-01 0.027 0 0
Galactose catabolism R-HSA-70370 9.401608e-01 0.027 0 0
Intraflagellar transport R-HSA-5620924 9.413404e-01 0.026 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 9.418394e-01 0.026 0 0
Formation of the Early Elongation Complex R-HSA-113418 9.418394e-01 0.026 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 9.418394e-01 0.026 0 0
Insulin receptor recycling R-HSA-77387 9.418394e-01 0.026 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 9.446713e-01 0.025 0 0
Plasma lipoprotein clearance R-HSA-8964043 9.452212e-01 0.024 0 0
G alpha (q) signalling events R-HSA-416476 9.460642e-01 0.024 0 0
Phospholipase C-mediated cascade: FGFR1 R-HSA-5654219 9.476753e-01 0.023 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.476753e-01 0.023 0 0
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770 9.476753e-01 0.023 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 9.476753e-01 0.023 0 0
Sulfide oxidation to sulfate R-HSA-1614517 9.476753e-01 0.023 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 9.501297e-01 0.022 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 9.503304e-01 0.022 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 9.503304e-01 0.022 0 0
Regulation of RAS by GAPs R-HSA-5658442 9.509149e-01 0.022 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 9.515020e-01 0.022 0 0
Hedgehog 'on' state R-HSA-5632684 9.524927e-01 0.021 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 9.531449e-01 0.021 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 9.533893e-01 0.021 0 0
Neurotransmitter clearance R-HSA-112311 9.533893e-01 0.021 0 0
Activated point mutants of FGFR2 R-HSA-2033519 9.542465e-01 0.020 0 0
Transport of connexons to the plasma membrane R-HSA-190872 9.542465e-01 0.020 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 9.542465e-01 0.020 0 0
Organic anion transport by SLC5/17/25 transporters R-HSA-428643 9.542465e-01 0.020 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 9.542465e-01 0.020 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 9.542465e-01 0.020 0 0
Post-translational protein phosphorylation R-HSA-8957275 9.547030e-01 0.020 0 0
Signaling by FGFR R-HSA-190236 9.547030e-01 0.020 0 0
Maturation of spike protein R-HSA-9694548 9.549922e-01 0.020 0 0
HSF1-dependent transactivation R-HSA-3371571 9.551433e-01 0.020 0 0
Phospholipid metabolism R-HSA-1483257 9.569862e-01 0.019 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 9.583075e-01 0.018 0 0
Orc1 removal from chromatin R-HSA-68949 9.590333e-01 0.018 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.592419e-01 0.018 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.592419e-01 0.018 0 0
Translation of Structural Proteins R-HSA-9683701 9.592419e-01 0.018 0 0
Switching of origins to a post-replicative state R-HSA-69052 9.594553e-01 0.018 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.598764e-01 0.018 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 9.599927e-01 0.018 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 9.599927e-01 0.018 0 0
Prostacyclin signalling through prostacyclin receptor R-HSA-392851 9.599927e-01 0.018 0 0
Regulation of signaling by CBL R-HSA-912631 9.599927e-01 0.018 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 9.599927e-01 0.018 0 0
Synthesis of 5-eicosatetraenoic acids R-HSA-2142688 9.599927e-01 0.018 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 9.599927e-01 0.018 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 9.599927e-01 0.018 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 9.599927e-01 0.018 0 0
The NLRP3 inflammasome R-HSA-844456 9.599927e-01 0.018 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 9.636544e-01 0.016 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 9.650176e-01 0.015 0 0
Phospholipase C-mediated cascade; FGFR2 R-HSA-5654221 9.650176e-01 0.015 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 9.650176e-01 0.015 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 9.650176e-01 0.015 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 9.650176e-01 0.015 0 0
Mitochondrial iron-sulfur cluster biogenesis R-HSA-1362409 9.650176e-01 0.015 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 9.650176e-01 0.015 0 0
Acyl chain remodelling of PI R-HSA-1482922 9.650176e-01 0.015 0 0
Keratan sulfate degradation R-HSA-2022857 9.650176e-01 0.015 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 9.650176e-01 0.015 0 0
Pregnenolone biosynthesis R-HSA-196108 9.650176e-01 0.015 0 0
Glycogen synthesis R-HSA-3322077 9.650176e-01 0.015 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 9.666352e-01 0.015 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 9.666352e-01 0.015 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 9.666925e-01 0.015 0 0
FGFR2 ligand binding and activation R-HSA-190241 9.694116e-01 0.013 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 9.694116e-01 0.013 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 9.694116e-01 0.013 0 0
Vitamin C (ascorbate) metabolism R-HSA-196836 9.694116e-01 0.013 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 9.694116e-01 0.013 0 0
Acyl chain remodelling of PG R-HSA-1482925 9.694116e-01 0.013 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 9.694116e-01 0.013 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 9.694116e-01 0.013 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 9.698385e-01 0.013 0 0
Gap junction trafficking R-HSA-190828 9.698385e-01 0.013 0 0
Surfactant metabolism R-HSA-5683826 9.698385e-01 0.013 0 0
Acyl chain remodelling of PC R-HSA-1482788 9.702510e-01 0.013 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 9.702510e-01 0.013 0 0
Kidney development R-HSA-9830369 9.719543e-01 0.012 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 9.732540e-01 0.012 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 9.732540e-01 0.012 0 0
Glutathione synthesis and recycling R-HSA-174403 9.732540e-01 0.012 0 0
Attachment and Entry R-HSA-9694614 9.732540e-01 0.012 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 9.734413e-01 0.012 0 0
Calnexin/calreticulin cycle R-HSA-901042 9.734413e-01 0.012 0 0
Signaling by NOTCH2 R-HSA-1980145 9.734413e-01 0.012 0 0
Phosphate bond hydrolysis by NUDT proteins R-HSA-2393930 9.734413e-01 0.012 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 9.743045e-01 0.011 0 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 9.751353e-01 0.011 0 0
Acyl chain remodelling of PE R-HSA-1482839 9.762998e-01 0.010 0 0
Defects in vitamin and cofactor metabolism R-HSA-3296482 9.762998e-01 0.010 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 9.762998e-01 0.010 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 9.766138e-01 0.010 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 9.766138e-01 0.010 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 9.766138e-01 0.010 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 9.766138e-01 0.010 0 0
Fructose metabolism R-HSA-5652084 9.766138e-01 0.010 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 9.766138e-01 0.010 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 9.777900e-01 0.010 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 9.777900e-01 0.010 0 0
Interferon alpha/beta signaling R-HSA-909733 9.779037e-01 0.010 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 9.784648e-01 0.009 0 0
FGFR2 mutant receptor activation R-HSA-1839126 9.788594e-01 0.009 0 0
FLT3 signaling in disease R-HSA-9682385 9.788594e-01 0.009 0 0
HSF1 activation R-HSA-3371511 9.788594e-01 0.009 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 9.788594e-01 0.009 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.793155e-01 0.009 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 9.795518e-01 0.009 0 0
Carnitine shuttle R-HSA-200425 9.795518e-01 0.009 0 0
Synthesis of pyrophosphates in the cytosol R-HSA-1855167 9.795518e-01 0.009 0 0
Cellular response to chemical stress R-HSA-9711123 9.799908e-01 0.009 0 0
tRNA Aminoacylation R-HSA-379724 9.805824e-01 0.009 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 9.821208e-01 0.008 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 9.821208e-01 0.008 0 0
Complex III assembly R-HSA-9865881 9.821208e-01 0.008 0 0
TNFs bind their physiological receptors R-HSA-5669034 9.821208e-01 0.008 0 0
TCR signaling R-HSA-202403 9.821713e-01 0.008 0 0
Collagen degradation R-HSA-1442490 9.823549e-01 0.008 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 9.823825e-01 0.008 0 0
alpha-linolenic acid (ALA) metabolism R-HSA-2046106 9.831992e-01 0.007 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 9.834143e-01 0.007 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 9.839734e-01 0.007 0 0
Mitochondrial protein import R-HSA-1268020 9.839734e-01 0.007 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 9.843672e-01 0.007 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 9.843672e-01 0.007 0 0
Hyaluronan degradation R-HSA-2160916 9.843672e-01 0.007 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 9.843672e-01 0.007 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 9.843672e-01 0.007 0 0
Defects in cobalamin (B12) metabolism R-HSA-3296469 9.843672e-01 0.007 0 0
Signaling by NOTCH4 R-HSA-9013694 9.849652e-01 0.007 0 0
Pentose phosphate pathway R-HSA-71336 9.850311e-01 0.007 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 9.850311e-01 0.007 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 9.853333e-01 0.006 0 0
Hedgehog ligand biogenesis R-HSA-5358346 9.853333e-01 0.006 0 0
MET activates PTK2 signaling R-HSA-8874081 9.863315e-01 0.006 0 0
Abacavir ADME R-HSA-2161522 9.863315e-01 0.006 0 0
Linoleic acid (LA) metabolism R-HSA-2046105 9.863315e-01 0.006 0 0
Suppression of phagosomal maturation R-HSA-9637687 9.863315e-01 0.006 0 0
Neddylation R-HSA-8951664 9.864523e-01 0.006 0 0
Attenuation phase R-HSA-3371568 9.866680e-01 0.006 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 9.877950e-01 0.005 0 0
GPCR downstream signalling R-HSA-388396 9.878735e-01 0.005 0 0
Signaling by FGFR3 in disease R-HSA-5655332 9.880490e-01 0.005 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 9.880490e-01 0.005 0 0
Synthesis of PE R-HSA-1483213 9.880490e-01 0.005 0 0
Synthesis of bile acids and bile salts via 27-hydroxycholesterol R-HSA-193807 9.880490e-01 0.005 0 0
Signaling by BMP R-HSA-201451 9.880490e-01 0.005 0 0
Maturation of hRSV A proteins R-HSA-9828806 9.880490e-01 0.005 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 9.881300e-01 0.005 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 9.881300e-01 0.005 0 0
Translation of Structural Proteins R-HSA-9694635 9.885740e-01 0.005 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 9.895509e-01 0.005 0 0
Prednisone ADME R-HSA-9757110 9.895509e-01 0.005 0 0
Pyrimidine salvage R-HSA-73614 9.895509e-01 0.005 0 0
Inflammasomes R-HSA-622312 9.895509e-01 0.005 0 0
Cholesterol biosynthesis R-HSA-191273 9.895824e-01 0.005 0 0
Integrin cell surface interactions R-HSA-216083 9.895824e-01 0.005 0 0
ER-Phagosome pathway R-HSA-1236974 9.903193e-01 0.004 0 0
Signaling by NOTCH3 R-HSA-9012852 9.903834e-01 0.004 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 9.905999e-01 0.004 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 9.908372e-01 0.004 0 0
Thyroxine biosynthesis R-HSA-209968 9.908640e-01 0.004 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 9.908640e-01 0.004 0 0
Activation of Matrix Metalloproteinases R-HSA-1592389 9.908640e-01 0.004 0 0
Regulation of gene expression in beta cells R-HSA-210745 9.908640e-01 0.004 0 0
mRNA Capping R-HSA-72086 9.908640e-01 0.004 0 0
Glucagon-type ligand receptors R-HSA-420092 9.908640e-01 0.004 0 0
Neurotransmitter release cycle R-HSA-112310 9.911389e-01 0.004 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 9.916388e-01 0.004 0 0
Response of Mtb to phagocytosis R-HSA-9637690 9.916388e-01 0.004 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 9.920122e-01 0.003 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 9.920122e-01 0.003 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 9.920122e-01 0.003 0 0
Mucopolysaccharidoses R-HSA-2206281 9.920122e-01 0.003 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.926973e-01 0.003 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 9.930162e-01 0.003 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 9.930162e-01 0.003 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.930162e-01 0.003 0 0
Synthesis of glycosylphosphatidylinositol (GPI) R-HSA-162710 9.930162e-01 0.003 0 0
SLC transporter disorders R-HSA-5619102 9.930533e-01 0.003 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 9.932210e-01 0.003 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 9.933907e-01 0.003 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 9.933907e-01 0.003 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 9.933907e-01 0.003 0 0
Fanconi Anemia Pathway R-HSA-6783310 9.933907e-01 0.003 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.934782e-01 0.003 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 9.934823e-01 0.003 0 0
HS-GAG degradation R-HSA-2024096 9.938940e-01 0.003 0 0
Regulation of pyruvate metabolism R-HSA-9861718 9.941263e-01 0.003 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 9.941263e-01 0.003 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 9.941263e-01 0.003 0 0
Collagen formation R-HSA-1474290 9.943409e-01 0.002 0 0
RAB geranylgeranylation R-HSA-8873719 9.943762e-01 0.002 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.943762e-01 0.002 0 0
Defective B3GALTL causes PpS R-HSA-5083635 9.946615e-01 0.002 0 0
Recycling of bile acids and salts R-HSA-159418 9.946615e-01 0.002 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 9.946615e-01 0.002 0 0
tRNA processing R-HSA-72306 9.947449e-01 0.002 0 0
alpha-linolenic (omega3) and linoleic (omega6) acid metabolism R-HSA-2046104 9.947815e-01 0.002 0 0
Translation R-HSA-72766 9.950309e-01 0.002 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.951189e-01 0.002 0 0
Glutamate and glutamine metabolism R-HSA-8964539 9.953326e-01 0.002 0 0
Heme degradation R-HSA-189483 9.953326e-01 0.002 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 9.953326e-01 0.002 0 0
NCAM signaling for neurite out-growth R-HSA-375165 9.954738e-01 0.002 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.955319e-01 0.002 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.955907e-01 0.002 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.958208e-01 0.002 0 0
eNOS activation R-HSA-203615 9.959194e-01 0.002 0 0
Gap junction assembly R-HSA-190861 9.959194e-01 0.002 0 0
Signaling by FGFR2 in disease R-HSA-5655253 9.963459e-01 0.002 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 9.964324e-01 0.002 0 0
Regulation of Apoptosis R-HSA-169911 9.964324e-01 0.002 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 9.964324e-01 0.002 0 0
Interleukin-10 signaling R-HSA-6783783 9.967566e-01 0.001 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 9.968810e-01 0.001 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 9.968810e-01 0.001 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.970795e-01 0.001 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 9.971221e-01 0.001 0 0
O-glycosylation of TSR domain-containing proteins R-HSA-5173214 9.972732e-01 0.001 0 0
SLC-mediated transport of organic cations R-HSA-549127 9.972732e-01 0.001 0 0
Beta-oxidation of very long chain fatty acids R-HSA-390247 9.972732e-01 0.001 0 0
Collagen chain trimerization R-HSA-8948216 9.972732e-01 0.001 0 0
Metabolism of folate and pterines R-HSA-196757 9.972732e-01 0.001 0 0
Nicotinate metabolism R-HSA-196807 9.973846e-01 0.001 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.974469e-01 0.001 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.974469e-01 0.001 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 9.976160e-01 0.001 0 0
Purine salvage R-HSA-74217 9.976160e-01 0.001 0 0
Elastic fibre formation R-HSA-1566948 9.976160e-01 0.001 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.977355e-01 0.001 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.979158e-01 0.001 0 0
Formation of the cornified envelope R-HSA-6809371 9.979609e-01 0.001 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 9.980688e-01 0.001 0 0
COPII-mediated vesicle transport R-HSA-204005 9.981247e-01 0.001 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 9.981779e-01 0.001 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 9.981779e-01 0.001 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 9.984071e-01 0.001 0 0
Dectin-2 family R-HSA-5621480 9.984219e-01 0.001 0 0
Purine catabolism R-HSA-74259 9.984998e-01 0.001 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 9.985904e-01 0.001 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.986015e-01 0.001 0 0
Heme biosynthesis R-HSA-189451 9.986074e-01 0.001 0 0
Peroxisomal protein import R-HSA-9033241 9.987609e-01 0.001 0 0
Regulation of beta-cell development R-HSA-186712 9.987609e-01 0.001 0 0
Glutathione conjugation R-HSA-156590 9.989023e-01 0.000 0 0
Defensins R-HSA-1461973 9.989357e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.989607e-01 0.000 0 0
Formation of paraxial mesoderm R-HSA-9793380 9.990277e-01 0.000 0 0
Endogenous sterols R-HSA-211976 9.990277e-01 0.000 0 0
Nucleotide salvage R-HSA-8956321 9.990277e-01 0.000 0 0
Methylation R-HSA-156581 9.990696e-01 0.000 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 9.990696e-01 0.000 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.991635e-01 0.000 0 0
Somitogenesis R-HSA-9824272 9.991867e-01 0.000 0 0
Degradation of cysteine and homocysteine R-HSA-1614558 9.991867e-01 0.000 0 0
Protein localization R-HSA-9609507 9.991891e-01 0.000 0 0
SLC-mediated transport of organic anions R-HSA-9955298 9.992367e-01 0.000 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 9.992890e-01 0.000 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 9.993784e-01 0.000 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.994567e-01 0.000 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 9.994724e-01 0.000 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 9.994724e-01 0.000 0 0
Mitochondrial protein degradation R-HSA-9837999 9.995153e-01 0.000 0 0
Keratan sulfate/keratin metabolism R-HSA-1638074 9.995250e-01 0.000 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.995250e-01 0.000 0 0
Glyoxylate metabolism and glycine degradation R-HSA-389661 9.995250e-01 0.000 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.995323e-01 0.000 0 0
Metabolism of steroid hormones R-HSA-196071 9.995323e-01 0.000 0 0
Peptide hormone metabolism R-HSA-2980736 9.995671e-01 0.000 0 0
Gastrulation R-HSA-9758941 9.995730e-01 0.000 0 0
Azathioprine ADME R-HSA-9748787 9.995848e-01 0.000 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.995862e-01 0.000 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.996371e-01 0.000 0 0
Complex IV assembly R-HSA-9864848 9.996371e-01 0.000 0 0
Cytosolic sulfonation of small molecules R-HSA-156584 9.996371e-01 0.000 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.996827e-01 0.000 0 0
ECM proteoglycans R-HSA-3000178 9.997138e-01 0.000 0 0
Metabolism of cofactors R-HSA-8978934 9.997138e-01 0.000 0 0
Metabolism of porphyrins R-HSA-189445 9.997138e-01 0.000 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.997272e-01 0.000 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 9.997469e-01 0.000 0 0
Pyruvate metabolism R-HSA-70268 9.997569e-01 0.000 0 0
FCERI mediated MAPK activation R-HSA-2871796 9.997606e-01 0.000 0 0
ABC-family proteins mediated transport R-HSA-382556 9.997738e-01 0.000 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 9.997763e-01 0.000 0 0
Paracetamol ADME R-HSA-9753281 9.997881e-01 0.000 0 0
Infectious disease R-HSA-5663205 9.997888e-01 0.000 0 0
Metabolism of amine-derived hormones R-HSA-209776 9.998148e-01 0.000 0 0
Digestion R-HSA-8935690 9.998148e-01 0.000 0 0
Downstream TCR signaling R-HSA-202424 9.998282e-01 0.000 0 0
G alpha (i) signalling events R-HSA-418594 9.998371e-01 0.000 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.998763e-01 0.000 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.998763e-01 0.000 0 0
ABC transporter disorders R-HSA-5619084 9.998794e-01 0.000 0 0
Complex I biogenesis R-HSA-6799198 9.999278e-01 0.000 0 0
Digestion and absorption R-HSA-8963743 9.999278e-01 0.000 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 9.999325e-01 0.000 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.999330e-01 0.000 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.999369e-01 0.000 0 0
Xenobiotics R-HSA-211981 9.999369e-01 0.000 0 0
Innate Immune System R-HSA-168249 9.999377e-01 0.000 0 0
Peroxisomal lipid metabolism R-HSA-390918 9.999428e-01 0.000 0 0
Disease R-HSA-1643685 9.999440e-01 0.000 0 0
Latent infection - Other responses of Mtb to phagocytosis R-HSA-1222499 9.999448e-01 0.000 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.999511e-01 0.000 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.999526e-01 0.000 0 0
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol R-HSA-193368 9.999579e-01 0.000 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.999607e-01 0.000 0 0
Extracellular matrix organization R-HSA-1474244 9.999677e-01 0.000 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.999694e-01 0.000 0 0
Glycosphingolipid catabolism R-HSA-9840310 9.999719e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.999753e-01 0.000 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 9.999754e-01 0.000 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.999759e-01 0.000 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 9.999762e-01 0.000 0 0
FCGR activation R-HSA-2029481 9.999856e-01 0.000 0 0
Iron uptake and transport R-HSA-917937 9.999857e-01 0.000 0 0
Visual phototransduction R-HSA-2187338 9.999870e-01 0.000 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.999877e-01 0.000 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.999886e-01 0.000 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.999916e-01 0.000 0 0
Sensory perception of taste R-HSA-9717189 9.999961e-01 0.000 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.999976e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999983e-01 0.000 0 0
Antimicrobial peptides R-HSA-6803157 9.999989e-01 0.000 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.999991e-01 0.000 0 0
Nucleotide catabolism R-HSA-8956319 9.999992e-01 0.000 0 0
Peptide ligand-binding receptors R-HSA-375276 9.999992e-01 0.000 0 0
Post-translational protein modification R-HSA-597592 9.999994e-01 0.000 0 0
Keratinization R-HSA-6805567 9.999996e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999998e-01 0.000 0 0
Post-translational modification: synthesis of GPI-anchored proteins R-HSA-163125 9.999998e-01 0.000 0 0
Transport of small molecules R-HSA-382551 1.000000e+00 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 1.000000e+00 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 1.000000e+00 0.000 0 0
Respiratory electron transport R-HSA-611105 1.000000e+00 0.000 0 0
Glycosphingolipid metabolism R-HSA-1660662 1.000000e+00 0.000 0 0
FCERI mediated NF-kB activation R-HSA-2871837 1.000000e+00 0.000 0 0
Regulation of Complement cascade R-HSA-977606 1.000000e+00 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 1.000000e+00 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 1.000000e+00 0.000 0 0
Metabolism of nucleotides R-HSA-15869 1.000000e+00 0.000 0 0
Arachidonate metabolism R-HSA-2142753 1.000000e+00 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 1.000000e+00 0.000 0 0
O-linked glycosylation R-HSA-5173105 1.000000e+00 0.000 0 0
Sphingolipid metabolism R-HSA-428157 1.000000e+00 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 1.000000e+00 0.000 0 0
Complement cascade R-HSA-166658 1.000000e+00 0.000 0 0
Metabolism of proteins R-HSA-392499 1.000000e+00 0.000 0 0
Diseases of glycosylation R-HSA-3781865 1.000000e+00 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 1.000000e+00 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.000000e+00 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 1.000000e+00 0.000 0 0
Drug ADME R-HSA-9748784 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 1.000000e+00 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 1.000000e+00 0.000 0 0
Expression and translocation of olfactory receptors R-HSA-9752946 1.000000e+00 -0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 -0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Olfactory Signaling Pathway R-HSA-381753 1.000000e+00 -0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 -0.000 0 0
Diseases of metabolism R-HSA-5668914 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.110223e-16 15.955 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.110223e-16 15.955 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.110223e-16 15.955 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 1.110223e-16 15.955 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 1.110223e-16 15.955 0 0
Eukaryotic Translation Elongation R-HSA-156842 1.110223e-16 15.955 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.110223e-16 15.955 0 0
HSF1-dependent transactivation R-HSA-3371571 1.110223e-16 15.955 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.110223e-16 15.955 0 0
Peptide chain elongation R-HSA-156902 1.110223e-16 15.955 0 0
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.110223e-16 15.955 0 0
M Phase R-HSA-68886 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Signaling by ROBO receptors R-HSA-376176 1.110223e-16 15.955 0 0
Cell-Cell communication R-HSA-1500931 1.110223e-16 15.955 0 0
Developmental Biology R-HSA-1266738 1.110223e-16 15.955 0 0
Viral Infection Pathways R-HSA-9824446 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Influenza Infection R-HSA-168255 1.110223e-16 15.955 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.220446e-16 15.654 0 0
Attenuation phase R-HSA-3371568 4.440892e-16 15.353 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 5.551115e-16 15.256 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 6.661338e-16 15.176 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 8.881784e-16 15.051 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 8.881784e-16 15.051 0 0
Cell Cycle R-HSA-1640170 8.881784e-16 15.051 0 0
Eukaryotic Translation Termination R-HSA-72764 1.221245e-15 14.913 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.443290e-15 14.841 0 0
Mitotic Prophase R-HSA-68875 2.220446e-15 14.654 0 0
Cell Cycle, Mitotic R-HSA-69278 2.331468e-15 14.632 0 0
Cell junction organization R-HSA-446728 2.553513e-15 14.593 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 2.997602e-15 14.523 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 3.219647e-15 14.492 0 0
Ribosome-associated quality control R-HSA-9948299 3.885781e-15 14.411 0 0
Selenocysteine synthesis R-HSA-2408557 4.884981e-15 14.311 0 0
Viral mRNA Translation R-HSA-192823 7.660539e-15 14.116 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 7.882583e-15 14.103 0 0
HSF1 activation R-HSA-3371511 9.547918e-15 14.020 0 0
SARS-CoV-1-host interactions R-HSA-9692914 1.842970e-14 13.734 0 0
Signal Transduction R-HSA-162582 2.531308e-14 13.597 0 0
Post NMDA receptor activation events R-HSA-438064 3.652634e-14 13.437 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 2.227107e-13 12.652 0 0
Metabolism of RNA R-HSA-8953854 2.476908e-13 12.606 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 2.599032e-13 12.585 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 2.763345e-13 12.559 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 3.246292e-13 12.489 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 3.553824e-13 12.449 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 3.802514e-13 12.420 0 0
G2/M DNA damage checkpoint R-HSA-69473 4.197753e-13 12.377 0 0
HCMV Early Events R-HSA-9609690 4.447553e-13 12.352 0 0
Aggrephagy R-HSA-9646399 5.000445e-13 12.301 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 5.309087e-13 12.275 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 6.559198e-13 12.183 0 0
Recycling pathway of L1 R-HSA-437239 8.197887e-13 12.086 0 0
Translation initiation complex formation R-HSA-72649 8.300027e-13 12.081 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.433076e-12 11.844 0 0
Infectious disease R-HSA-5663205 1.464162e-12 11.834 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.529776e-12 11.815 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.544431e-12 11.811 0 0
Selenoamino acid metabolism R-HSA-2408522 1.753264e-12 11.756 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 4.887646e-12 11.311 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 4.909406e-12 11.309 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 5.141998e-12 11.289 0 0
L1CAM interactions R-HSA-373760 6.526668e-12 11.185 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 7.294387e-12 11.137 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 7.294387e-12 11.137 0 0
PRC2 methylates histones and DNA R-HSA-212300 1.175127e-11 10.930 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 1.194478e-11 10.923 0 0
Selective autophagy R-HSA-9663891 1.313361e-11 10.882 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.291545e-11 10.889 0 0
Gap junction trafficking and regulation R-HSA-157858 1.321687e-11 10.879 0 0
Cellular response to starvation R-HSA-9711097 1.566791e-11 10.805 0 0
HCMV Infection R-HSA-9609646 2.235989e-11 10.651 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.491451e-11 10.604 0 0
Gap junction trafficking R-HSA-190828 2.492451e-11 10.603 0 0
Cell-cell junction organization R-HSA-421270 2.492506e-11 10.603 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 2.819978e-11 10.550 0 0
Adherens junctions interactions R-HSA-418990 3.391742e-11 10.470 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 3.434175e-11 10.464 0 0
SARS-CoV-1 Infection R-HSA-9678108 4.150624e-11 10.382 0 0
Transport of connexons to the plasma membrane R-HSA-190872 4.272638e-11 10.369 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.547618e-11 10.342 0 0
G2/M Checkpoints R-HSA-69481 4.826017e-11 10.316 0 0
Translation R-HSA-72766 5.868905e-11 10.231 0 0
DNA methylation R-HSA-5334118 6.308110e-11 10.200 0 0
PKR-mediated signaling R-HSA-9833482 7.684842e-11 10.114 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 8.570722e-11 10.067 0 0
Apoptosis R-HSA-109581 1.204171e-10 9.919 1 0
Interferon Signaling R-HSA-913531 1.213534e-10 9.916 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.383720e-10 9.859 0 0
Defective pyroptosis R-HSA-9710421 1.565225e-10 9.805 0 0
rRNA processing R-HSA-72312 1.621692e-10 9.790 0 0
EPH-Ephrin signaling R-HSA-2682334 2.074911e-10 9.683 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 2.323258e-10 9.634 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 2.736389e-10 9.563 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 2.738774e-10 9.562 0 0
Signaling by RAS mutants R-HSA-6802949 3.680345e-10 9.434 0 0
Signaling downstream of RAS mutants R-HSA-9649948 3.680345e-10 9.434 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 3.680345e-10 9.434 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 3.680345e-10 9.434 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 3.612207e-10 9.442 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 3.680345e-10 9.434 0 0
Apoptotic execution phase R-HSA-75153 3.680345e-10 9.434 1 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 3.943967e-10 9.404 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 4.601728e-10 9.337 0 0
Diseases of programmed cell death R-HSA-9645723 4.601728e-10 9.337 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 5.366751e-10 9.270 0 0
Signaling by RAF1 mutants R-HSA-9656223 7.211194e-10 9.142 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 7.389725e-10 9.131 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 7.786858e-10 9.109 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.032369e-09 8.986 0 0
DNA Double Strand Break Response R-HSA-5693606 1.203657e-09 8.919 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 1.257928e-09 8.900 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 1.330484e-09 8.876 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 1.378191e-09 8.861 0 0
Meiotic recombination R-HSA-912446 1.365300e-09 8.865 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.391902e-09 8.856 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.466340e-09 8.834 0 0
Programmed Cell Death R-HSA-5357801 1.634782e-09 8.787 1 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.670735e-09 8.777 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.747551e-09 8.758 0 0
RNA Polymerase I Transcription R-HSA-73864 1.862562e-09 8.730 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 2.548556e-09 8.594 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 2.604258e-09 8.584 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 2.823264e-09 8.549 0 0
Platelet activation, signaling and aggregation R-HSA-76002 2.915458e-09 8.535 0 0
Packaging Of Telomere Ends R-HSA-171306 3.175778e-09 8.498 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 3.300443e-09 8.481 0 0
HDACs deacetylate histones R-HSA-3214815 3.564524e-09 8.448 0 0
Gene Silencing by RNA R-HSA-211000 3.694120e-09 8.432 0 0
Signaling by VEGF R-HSA-194138 3.712772e-09 8.430 0 0
Autophagy R-HSA-9612973 4.064479e-09 8.391 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 4.354340e-09 8.361 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 4.354340e-09 8.361 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 4.505095e-09 8.346 0 0
Immune System R-HSA-168256 4.544429e-09 8.343 0 0
Cellular Senescence R-HSA-2559583 4.912923e-09 8.309 0 0
Estrogen-dependent gene expression R-HSA-9018519 4.925682e-09 8.308 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 5.143411e-09 8.289 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 5.677261e-09 8.246 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 6.059710e-09 8.218 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 6.995646e-09 8.155 0 0
Regulation of endogenous retroelements R-HSA-9842860 7.074438e-09 8.150 0 0
Disease R-HSA-1643685 7.868543e-09 8.104 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 8.496231e-09 8.071 0 0
Macroautophagy R-HSA-1632852 9.340649e-09 8.030 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.137600e-08 7.944 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 1.137603e-08 7.944 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.148619e-08 7.940 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.239292e-08 7.907 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 1.337731e-08 7.874 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.618280e-08 7.791 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.628407e-08 7.788 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.640330e-08 7.785 0 0
Amyloid fiber formation R-HSA-977225 1.801630e-08 7.744 0 0
Hemostasis R-HSA-109582 1.856303e-08 7.731 0 0
Protein folding R-HSA-391251 3.026060e-08 7.519 0 0
G2/M Transition R-HSA-69275 3.408529e-08 7.467 0 0
Oncogenic MAPK signaling R-HSA-6802957 3.554191e-08 7.449 0 0
Meiosis R-HSA-1500620 3.554191e-08 7.449 0 0
Gap junction assembly R-HSA-190861 3.925693e-08 7.406 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 3.925693e-08 7.406 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 4.072420e-08 7.390 0 0
Mitotic G2-G2/M phases R-HSA-453274 4.175768e-08 7.379 0 0
MAP2K and MAPK activation R-HSA-5674135 4.233764e-08 7.373 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 5.587550e-08 7.253 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 5.671204e-08 7.246 0 0
Signaling by ERBB2 R-HSA-1227986 6.533105e-08 7.185 0 0
Mitotic Anaphase R-HSA-68882 5.912124e-08 7.228 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 6.480482e-08 7.188 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 7.951049e-08 7.100 0 0
Cleavage of the damaged purine R-HSA-110331 8.762344e-08 7.057 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 8.974686e-08 7.047 0 0
Processing of DNA double-strand break ends R-HSA-5693607 9.372862e-08 7.028 0 0
Meiotic synapsis R-HSA-1221632 9.595085e-08 7.018 0 0
MAPK family signaling cascades R-HSA-5683057 1.061859e-07 6.974 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.088816e-07 6.963 0 0
Nucleosome assembly R-HSA-774815 1.088816e-07 6.963 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 1.102388e-07 6.958 0 0
Depurination R-HSA-73927 1.129382e-07 6.947 0 0
Glycolysis R-HSA-70171 1.155791e-07 6.937 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.304757e-07 6.884 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.444914e-07 6.840 0 0
Membrane Trafficking R-HSA-199991 1.648754e-07 6.783 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.915476e-07 6.718 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 2.096944e-07 6.678 0 0
Regulation of CDH1 Function R-HSA-9764561 2.131780e-07 6.671 0 0
Nuclear Envelope Breakdown R-HSA-2980766 2.131780e-07 6.671 0 0
Cell Cycle Checkpoints R-HSA-69620 2.188661e-07 6.660 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.531547e-07 6.597 0 0
Mitotic Prometaphase R-HSA-68877 2.307816e-07 6.637 0 0
SARS-CoV-2 Infection R-HSA-9694516 3.278803e-07 6.484 0 0
ESR-mediated signaling R-HSA-8939211 3.640252e-07 6.439 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 3.668173e-07 6.436 0 0
Depyrimidination R-HSA-73928 3.668173e-07 6.436 0 0
HATs acetylate histones R-HSA-3214847 4.452401e-07 6.351 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.732791e-07 6.325 0 0
Reproduction R-HSA-1474165 5.463959e-07 6.262 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 5.506333e-07 6.259 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 6.359200e-07 6.197 0 0
Signaling by PTK6 R-HSA-8848021 6.359200e-07 6.197 0 0
mRNA Splicing R-HSA-72172 6.734332e-07 6.172 0 0
Adaptive Immune System R-HSA-1280218 7.460872e-07 6.127 0 0
Assembly of the pre-replicative complex R-HSA-68867 7.546047e-07 6.122 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.602719e-07 6.119 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 8.333596e-07 6.079 0 0
Chaperone Mediated Autophagy R-HSA-9613829 8.823245e-07 6.054 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 9.671486e-07 6.015 0 0
Activation of HOX genes during differentiation R-HSA-5619507 9.671486e-07 6.015 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.036105e-06 5.985 1 1
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.045678e-06 5.981 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 1.045678e-06 5.981 0 0
SARS-CoV Infections R-HSA-9679506 1.046443e-06 5.980 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.268495e-06 5.897 0 0
Ub-specific processing proteases R-HSA-5689880 1.300714e-06 5.886 0 0
Glucose metabolism R-HSA-70326 1.456941e-06 5.837 0 0
Nephrin family interactions R-HSA-373753 1.734183e-06 5.761 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.775442e-06 5.751 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.852358e-06 5.732 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.091928e-06 5.679 0 0
Kinesins R-HSA-983189 2.003479e-06 5.698 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.120045e-06 5.674 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 2.136805e-06 5.670 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 3.155437e-06 5.501 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 3.797503e-06 5.421 0 0
Co-inhibition by PD-1 R-HSA-389948 4.155385e-06 5.381 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 4.465304e-06 5.350 0 0
Platelet degranulation R-HSA-114608 4.763303e-06 5.322 0 0
Interleukin-12 signaling R-HSA-9020591 4.800158e-06 5.319 0 0
COPI-mediated anterograde transport R-HSA-6807878 5.269993e-06 5.278 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 5.269993e-06 5.278 0 0
Cilium Assembly R-HSA-5617833 5.578012e-06 5.254 0 0
Telomere Maintenance R-HSA-157579 5.938763e-06 5.226 0 0
Homology Directed Repair R-HSA-5693538 6.049825e-06 5.218 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 6.817397e-06 5.166 0 0
Chromosome Maintenance R-HSA-73886 8.253030e-06 5.083 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 8.253030e-06 5.083 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 8.321735e-06 5.080 0 0
Hedgehog 'off' state R-HSA-5610787 8.425881e-06 5.074 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 9.442115e-06 5.025 0 0
Signaling by WNT R-HSA-195721 9.844296e-06 5.007 0 0
Deubiquitination R-HSA-5688426 1.095390e-05 4.960 0 0
Regulation of signaling by CBL R-HSA-912631 1.127376e-05 4.948 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.178381e-05 4.929 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.230445e-05 4.910 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.346599e-05 4.871 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.381315e-05 4.860 0 0
Organelle biogenesis and maintenance R-HSA-1852241 1.471719e-05 4.832 0 0
Regulation of KIT signaling R-HSA-1433559 1.506458e-05 4.822 0 0
Semaphorin interactions R-HSA-373755 1.568635e-05 4.804 0 0
Signaling by Hedgehog R-HSA-5358351 1.657125e-05 4.781 0 0
Metabolism of proteins R-HSA-392499 1.773800e-05 4.751 0 0
DCC mediated attractive signaling R-HSA-418885 2.120990e-05 4.673 0 0
DAG and IP3 signaling R-HSA-1489509 2.282477e-05 4.642 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 2.120990e-05 4.673 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.106060e-05 4.677 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 2.120990e-05 4.673 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.120990e-05 4.673 0 0
Interleukin-12 family signaling R-HSA-447115 2.242943e-05 4.649 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 2.395227e-05 4.621 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 2.589997e-05 4.587 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.064647e-05 4.514 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.064647e-05 4.514 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 3.548722e-05 4.450 0 0
PECAM1 interactions R-HSA-210990 3.605449e-05 4.443 0 0
Host Interactions of HIV factors R-HSA-162909 3.763400e-05 4.424 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 4.057720e-05 4.392 0 0
Epigenetic regulation of gene expression R-HSA-212165 4.158661e-05 4.381 0 0
Transmission across Chemical Synapses R-HSA-112315 4.158661e-05 4.381 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 4.513238e-05 4.346 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 4.513238e-05 4.346 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 4.513238e-05 4.346 0 0
Nef and signal transduction R-HSA-164944 4.860561e-05 4.313 0 0
Intracellular signaling by second messengers R-HSA-9006925 4.914159e-05 4.309 0 0
Separation of Sister Chromatids R-HSA-2467813 5.086089e-05 4.294 0 0
FLT3 Signaling R-HSA-9607240 5.158556e-05 4.287 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 5.263267e-05 4.279 0 0
Vesicle-mediated transport R-HSA-5653656 5.301948e-05 4.276 0 0
Long-term potentiation R-HSA-9620244 6.751636e-05 4.171 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 6.861498e-05 4.164 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 6.867580e-05 4.163 0 0
Ephrin signaling R-HSA-3928664 6.987343e-05 4.156 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 7.001352e-05 4.155 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 7.001352e-05 4.155 0 0
Ca-dependent events R-HSA-111996 7.199666e-05 4.143 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 7.771747e-05 4.109 0 0
RAF activation R-HSA-5673000 8.205064e-05 4.086 0 0
Signaling by SCF-KIT R-HSA-1433557 8.454176e-05 4.073 0 0
HCMV Late Events R-HSA-9610379 8.639645e-05 4.064 0 0
Signaling by Interleukins R-HSA-449147 8.778801e-05 4.057 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 9.009360e-05 4.045 0 0
Rap1 signalling R-HSA-392517 9.077348e-05 4.042 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.026943e-04 3.988 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.034521e-04 3.985 0 0
MHC class II antigen presentation R-HSA-2132295 1.106011e-04 3.956 0 0
Calmodulin induced events R-HSA-111933 1.169607e-04 3.932 0 0
CaM pathway R-HSA-111997 1.169607e-04 3.932 0 0
Signaling by EGFR R-HSA-177929 1.200476e-04 3.921 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.232452e-04 3.909 0 0
Chromatin modifying enzymes R-HSA-3247509 1.260527e-04 3.899 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.386636e-04 3.858 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 1.416088e-04 3.849 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 1.660607e-04 3.780 0 0
Gap junction degradation R-HSA-190873 1.845614e-04 3.734 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.885468e-04 3.725 0 0
Intraflagellar transport R-HSA-5620924 1.787012e-04 3.748 0 0
Muscle contraction R-HSA-397014 2.091088e-04 3.680 0 0
TCF dependent signaling in response to WNT R-HSA-201681 2.090409e-04 3.680 0 0
DNA Replication R-HSA-69306 1.827210e-04 3.738 0 0
Signaling by NOTCH R-HSA-157118 1.788460e-04 3.748 0 0
PLC beta mediated events R-HSA-112043 2.275659e-04 3.643 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.331740e-04 3.632 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.331740e-04 3.632 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.382338e-04 3.623 0 0
Centrosome maturation R-HSA-380287 2.897410e-04 3.538 0 0
ISG15 antiviral mechanism R-HSA-1169408 2.897410e-04 3.538 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 2.897410e-04 3.538 0 0
Chromatin organization R-HSA-4839726 2.949176e-04 3.530 0 0
Negative regulation of MAPK pathway R-HSA-5675221 3.034946e-04 3.518 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 3.159983e-04 3.500 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 3.201719e-04 3.495 0 0
ER to Golgi Anterograde Transport R-HSA-199977 3.311599e-04 3.480 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.484341e-04 3.458 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 3.484341e-04 3.458 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 3.722155e-04 3.429 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.075064e-04 3.390 0 0
Base Excision Repair R-HSA-73884 4.075064e-04 3.390 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 4.228035e-04 3.374 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 4.382157e-04 3.358 0 0
G-protein mediated events R-HSA-112040 4.546694e-04 3.342 0 0
Developmental Cell Lineages R-HSA-9734767 6.080731e-04 3.216 0 0
Neuronal System R-HSA-112316 6.576974e-04 3.182 0 0
Clathrin-mediated endocytosis R-HSA-8856828 6.839945e-04 3.165 0 0
Neutrophil degranulation R-HSA-6798695 8.385824e-04 3.076 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 8.561072e-04 3.067 0 0
Late endosomal microautophagy R-HSA-9615710 8.561072e-04 3.067 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 9.661768e-04 3.015 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 9.661768e-04 3.015 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 1.005906e-03 2.997 0 0
Activation of BH3-only proteins R-HSA-114452 1.005906e-03 2.997 0 0
Protein ubiquitination R-HSA-8852135 1.027724e-03 2.988 0 0
HIV Infection R-HSA-162906 1.136087e-03 2.945 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.139069e-03 2.943 0 0
Formation of annular gap junctions R-HSA-196025 1.354185e-03 2.868 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 1.354185e-03 2.868 0 0
Parasite infection R-HSA-9664407 1.388888e-03 2.857 0 0
Leishmania phagocytosis R-HSA-9664417 1.388888e-03 2.857 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 1.388888e-03 2.857 0 0
Smooth Muscle Contraction R-HSA-445355 1.400529e-03 2.854 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 1.404482e-03 2.852 0 0
Signaling by KIT in disease R-HSA-9669938 1.404482e-03 2.852 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.442132e-03 2.841 0 0
Spry regulation of FGF signaling R-HSA-1295596 1.442132e-03 2.841 0 0
Integrin signaling R-HSA-354192 1.581695e-03 2.801 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 1.673600e-03 2.776 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.800748e-03 2.745 0 0
Negative regulation of FLT3 R-HSA-9706369 1.800748e-03 2.745 0 0
Striated Muscle Contraction R-HSA-390522 1.821892e-03 2.739 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 1.821892e-03 2.739 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.855329e-03 2.732 0 0
Netrin-1 signaling R-HSA-373752 1.965441e-03 2.707 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 2.093645e-03 2.679 0 0
Signaling by ALK in cancer R-HSA-9700206 2.093645e-03 2.679 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 2.472176e-03 2.607 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 2.472176e-03 2.607 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 2.594353e-03 2.586 0 0
Loss of MECP2 binding ability to 5hmC-DNA R-HSA-9022534 3.396397e-03 2.469 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 3.216994e-03 2.493 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.707693e-03 2.567 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.718520e-03 2.566 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 3.474737e-03 2.459 0 0
Degradation of CDH1 R-HSA-9766229 3.417632e-03 2.466 0 0
Gluconeogenesis R-HSA-70263 3.075761e-03 2.512 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 3.484973e-03 2.458 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 3.484973e-03 2.458 0 0
Innate Immune System R-HSA-168249 3.659237e-03 2.437 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 3.910570e-03 2.408 0 0
PCP/CE pathway R-HSA-4086400 4.285173e-03 2.368 0 0
Response of endothelial cells to shear stress R-HSA-9860931 4.362345e-03 2.360 0 0
Opioid Signalling R-HSA-111885 4.362345e-03 2.360 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 4.386648e-03 2.358 0 0
Co-inhibition by CTLA4 R-HSA-389513 4.630084e-03 2.334 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 4.905247e-03 2.309 0 0
Signaling by MET R-HSA-6806834 5.009825e-03 2.300 0 0
Signaling by FGFR2 R-HSA-5654738 5.009825e-03 2.300 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 5.042424e-03 2.297 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 5.042424e-03 2.297 0 0
EGFR downregulation R-HSA-182971 5.451739e-03 2.263 0 0
Trafficking of AMPA receptors R-HSA-399719 5.451739e-03 2.263 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 5.451739e-03 2.263 0 0
Gene expression (Transcription) R-HSA-74160 6.276094e-03 2.202 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 6.335242e-03 2.198 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 6.354235e-03 2.197 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 6.354235e-03 2.197 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 6.354235e-03 2.197 0 0
Mitochondrial calcium ion transport R-HSA-8949215 6.354235e-03 2.197 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 6.646900e-03 2.177 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 6.704921e-03 2.174 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 6.734949e-03 2.172 0 0
TCR signaling R-HSA-202403 6.828425e-03 2.166 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 6.972181e-03 2.157 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 6.972181e-03 2.157 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 7.244215e-03 2.140 0 0
mTORC1-mediated signalling R-HSA-166208 7.366122e-03 2.133 0 0
Manipulation of host energy metabolism R-HSA-9636667 7.431285e-03 2.129 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 7.431521e-03 2.129 0 0
DNA Repair R-HSA-73894 7.450768e-03 2.128 0 0
RMTs methylate histone arginines R-HSA-3214858 7.450971e-03 2.128 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 7.458196e-03 2.127 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 7.705110e-03 2.113 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 7.837740e-03 2.106 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 8.024983e-03 2.096 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 8.216847e-03 2.085 0 0
Syndecan interactions R-HSA-3000170 8.485177e-03 2.071 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 8.666022e-03 2.062 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.755097e-03 2.058 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 8.778059e-03 2.057 0 0
Nuclear import of Rev protein R-HSA-180746 8.778059e-03 2.057 0 0
HIV Life Cycle R-HSA-162587 9.038585e-03 2.044 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 9.039145e-03 2.044 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 9.255244e-03 2.034 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 9.256510e-03 2.034 0 0
Protein methylation R-HSA-8876725 9.256510e-03 2.034 0 0
Signaling by ERBB4 R-HSA-1236394 9.319382e-03 2.031 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 9.716667e-03 2.012 0 0
Neurodegenerative Diseases R-HSA-8863678 9.716667e-03 2.012 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.718897e-03 2.012 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 9.796486e-03 2.009 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 9.796486e-03 2.009 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.030751e-02 1.987 0 0
Co-stimulation by CD28 R-HSA-389356 1.086221e-02 1.964 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 1.089631e-02 1.963 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 1.089631e-02 1.963 0 0
GPVI-mediated activation cascade R-HSA-114604 1.089631e-02 1.963 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.089631e-02 1.963 0 0
RET signaling R-HSA-8853659 1.089631e-02 1.963 0 0
Parasitic Infection Pathways R-HSA-9824443 1.098965e-02 1.959 0 0
Leishmania infection R-HSA-9658195 1.098965e-02 1.959 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.106567e-02 1.956 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 1.158059e-02 1.936 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 1.194320e-02 1.923 0 0
Type I hemidesmosome assembly R-HSA-446107 1.194320e-02 1.923 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.194320e-02 1.923 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.194320e-02 1.923 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.194320e-02 1.923 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 1.194320e-02 1.923 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 1.208074e-02 1.918 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.284836e-02 1.891 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.284836e-02 1.891 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.284836e-02 1.891 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.284836e-02 1.891 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.284836e-02 1.891 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.293799e-02 1.888 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.293799e-02 1.888 0 0
Loss of MECP2 binding ability to 5mC-DNA R-HSA-9022538 1.952619e-02 1.709 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 1.508321e-02 1.822 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 1.508321e-02 1.822 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 1.508321e-02 1.822 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.744018e-02 1.758 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 1.973555e-02 1.705 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.471593e-02 1.832 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.617269e-02 1.791 0 0
mRNA 3'-end processing R-HSA-72187 1.528532e-02 1.816 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.772606e-02 1.751 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 1.413547e-02 1.850 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 1.853424e-02 1.732 0 0
GAB1 signalosome R-HSA-180292 1.744018e-02 1.758 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 1.503391e-02 1.823 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 1.773071e-02 1.751 0 0
DAP12 signaling R-HSA-2424491 1.973555e-02 1.705 0 0
Josephin domain DUBs R-HSA-5689877 1.853424e-02 1.732 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 1.937879e-02 1.713 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 1.413547e-02 1.850 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.413547e-02 1.850 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 1.937879e-02 1.713 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 1.937879e-02 1.713 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 1.586531e-02 1.800 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 1.773071e-02 1.751 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 1.617269e-02 1.791 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.481057e-02 1.829 0 0
Signaling by Hippo R-HSA-2028269 1.508321e-02 1.822 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 1.765540e-02 1.753 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.413547e-02 1.850 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.471593e-02 1.832 0 0
RNA Polymerase II Transcription R-HSA-73857 1.590359e-02 1.799 0 0
PIP3 activates AKT signaling R-HSA-1257604 1.747526e-02 1.758 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.487470e-02 1.828 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.786367e-02 1.748 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 1.381762e-02 1.860 0 0
Signaling by FGFR R-HSA-190236 1.973927e-02 1.705 0 0
Translesion Synthesis by POLH R-HSA-110320 2.001450e-02 1.699 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 2.113348e-02 1.675 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.120553e-02 1.674 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 2.188341e-02 1.660 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 2.188341e-02 1.660 0 0
Downstream signal transduction R-HSA-186763 2.188341e-02 1.660 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 2.244794e-02 1.649 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 2.281096e-02 1.642 0 0
Negative regulation of MET activity R-HSA-6807004 2.281096e-02 1.642 0 0
Signal transduction by L1 R-HSA-445144 2.281096e-02 1.642 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 2.299262e-02 1.638 0 0
Signaling by FGFR4 R-HSA-5654743 2.299262e-02 1.638 0 0
Generic Transcription Pathway R-HSA-212436 2.354155e-02 1.628 0 0
G1 Phase R-HSA-69236 2.495857e-02 1.603 0 0
Cyclin D associated events in G1 R-HSA-69231 2.495857e-02 1.603 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.495857e-02 1.603 0 0
Metabolism of amino acids and derivatives R-HSA-71291 2.510690e-02 1.600 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 2.662110e-02 1.575 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 2.662110e-02 1.575 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 2.662110e-02 1.575 0 0
Activation of RAC1 R-HSA-428540 2.677596e-02 1.572 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 2.677596e-02 1.572 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 2.677596e-02 1.572 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.703355e-02 1.568 0 0
Signaling by FGFR3 R-HSA-5654741 2.703355e-02 1.568 0 0
MECP2 regulates transcription of genes involved in GABA signaling R-HSA-9022927 2.735103e-02 1.563 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.735103e-02 1.563 0 0
MTF1 activates gene expression R-HSA-5660489 2.735103e-02 1.563 0 0
Signaling by NTRKs R-HSA-166520 2.739736e-02 1.562 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 2.762521e-02 1.559 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 2.908561e-02 1.536 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 2.908561e-02 1.536 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 2.921663e-02 1.534 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 2.921963e-02 1.534 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 2.963496e-02 1.528 0 0
IRE1alpha activates chaperones R-HSA-381070 3.061561e-02 1.514 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 3.151677e-02 1.501 0 0
Pervasive developmental disorders R-HSA-9005895 3.151677e-02 1.501 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 3.151677e-02 1.501 0 0
Disorders of Nervous System Development R-HSA-9697154 3.151677e-02 1.501 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.151677e-02 1.501 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 3.151677e-02 1.501 0 0
VLDLR internalisation and degradation R-HSA-8866427 3.151677e-02 1.501 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 3.151872e-02 1.501 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 3.170047e-02 1.499 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 3.196657e-02 1.495 0 0
Mitophagy R-HSA-5205647 3.196657e-02 1.495 0 0
FGFR2 alternative splicing R-HSA-6803529 3.256951e-02 1.487 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 3.256951e-02 1.487 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 3.256951e-02 1.487 0 0
Mitochondrial protein degradation R-HSA-9837999 3.577921e-02 1.446 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 3.621638e-02 1.441 0 0
NTRK2 activates RAC1 R-HSA-9032759 3.621638e-02 1.441 0 0
CD28 dependent Vav1 pathway R-HSA-389359 3.666660e-02 1.436 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 3.666660e-02 1.436 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 3.666660e-02 1.436 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 4.023921e-02 1.395 0 0
Deadenylation of mRNA R-HSA-429947 4.023921e-02 1.395 0 0
Plasma lipoprotein assembly R-HSA-8963898 4.023921e-02 1.395 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 4.050803e-02 1.392 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 4.109959e-02 1.386 0 0
Ovarian tumor domain proteases R-HSA-5689896 4.116213e-02 1.386 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 4.221974e-02 1.374 0 0
HDL assembly R-HSA-8963896 4.221974e-02 1.374 0 0
MET promotes cell motility R-HSA-8875878 4.454744e-02 1.351 0 0
Regulated Necrosis R-HSA-5218859 4.565513e-02 1.341 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 4.602258e-02 1.337 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 4.602258e-02 1.337 0 0
Sodium-coupled phosphate cotransporters R-HSA-427652 4.602258e-02 1.337 0 0
Maturation of protein E R-HSA-9683683 4.602258e-02 1.337 0 0
Maturation of protein E R-HSA-9694493 4.602258e-02 1.337 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.777473e-02 1.321 0 0
RAS processing R-HSA-9648002 4.809448e-02 1.318 0 0
Pentose phosphate pathway R-HSA-71336 4.809448e-02 1.318 0 0
Erythropoietin activates RAS R-HSA-9027284 4.816873e-02 1.317 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 4.816873e-02 1.317 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 4.816873e-02 1.317 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 4.816873e-02 1.317 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 4.832079e-02 1.316 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.884821e-02 1.311 0 0
MET activates PTK2 signaling R-HSA-8874081 4.884821e-02 1.311 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.108344e-02 1.292 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.108344e-02 1.292 0 0
Interferon alpha/beta signaling R-HSA-909733 5.158933e-02 1.287 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 5.180378e-02 1.286 0 0
Generation of second messenger molecules R-HSA-202433 5.180378e-02 1.286 0 0
XBP1(S) activates chaperone genes R-HSA-381038 5.236743e-02 1.281 0 0
Interaction between L1 and Ankyrins R-HSA-445095 5.350375e-02 1.272 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.450459e-02 1.264 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.450459e-02 1.264 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.450459e-02 1.264 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 5.450459e-02 1.264 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.450459e-02 1.264 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 5.567559e-02 1.254 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 5.567559e-02 1.254 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 5.667643e-02 1.247 0 0
Erythropoietin activates STAT5 R-HSA-9027283 5.667643e-02 1.247 0 0
G2/M DNA replication checkpoint R-HSA-69478 5.667643e-02 1.247 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.667643e-02 1.247 0 0
Ion homeostasis R-HSA-5578775 5.753596e-02 1.240 0 0
Signaling by FGFR1 R-HSA-5654736 5.753596e-02 1.240 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 5.753596e-02 1.240 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 5.839142e-02 1.234 0 0
Hereditary fructose intolerance R-HSA-5657560 8.133540e-02 1.090 0 0
TICAM1 deficiency - HSE R-HSA-5602566 8.133540e-02 1.090 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 8.133540e-02 1.090 0 0
MECP2 regulates transcription factors R-HSA-9022707 6.809085e-02 1.167 0 0
Role of ABL in ROBO-SLIT signaling R-HSA-428890 6.809085e-02 1.167 0 0
SOS-mediated signalling R-HSA-112412 6.809085e-02 1.167 0 0
Disinhibition of SNARE formation R-HSA-114516 6.809085e-02 1.167 0 0
Lipophagy R-HSA-9613354 9.288142e-02 1.032 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 9.288142e-02 1.032 0 0
Binding and entry of HIV virion R-HSA-173107 1.061109e-01 0.974 0 0
MECP2 regulates transcription of neuronal ligands R-HSA-9022702 1.061109e-01 0.974 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 1.061109e-01 0.974 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 8.349481e-02 1.078 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 8.349481e-02 1.078 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 1.086999e-01 0.964 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 7.746069e-02 1.111 0 0
Metabolism of non-coding RNA R-HSA-194441 6.840752e-02 1.165 0 0
snRNP Assembly R-HSA-191859 6.840752e-02 1.165 0 0
Early Phase of HIV Life Cycle R-HSA-162594 9.999695e-02 1.000 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 6.121703e-02 1.213 0 0
Disorders of Developmental Biology R-HSA-9675151 6.121703e-02 1.213 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.031849e-01 0.986 0 0
DNA Damage Bypass R-HSA-73893 9.773551e-02 1.010 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 6.809085e-02 1.167 0 0
Budding and maturation of HIV virion R-HSA-162588 7.442316e-02 1.128 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 1.176304e-01 0.929 0 0
G0 and Early G1 R-HSA-1538133 8.021271e-02 1.096 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 6.809085e-02 1.167 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 8.018448e-02 1.096 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 6.390626e-02 1.194 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 6.121703e-02 1.213 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 1.087819e-01 0.963 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 9.999695e-02 1.000 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 8.349481e-02 1.078 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 1.003343e-01 0.999 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 1.176839e-01 0.929 0 0
Regulation of necroptotic cell death R-HSA-5675482 8.621858e-02 1.064 0 0
Inhibition of PKR R-HSA-169131 8.133540e-02 1.090 0 0
Regulation of PTEN localization R-HSA-8948747 6.809085e-02 1.167 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 8.018448e-02 1.096 0 0
PKA activation R-HSA-163615 7.572495e-02 1.121 0 0
PKA activation in glucagon signalling R-HSA-164378 7.572495e-02 1.121 0 0
DARPP-32 events R-HSA-180024 6.350908e-02 1.197 0 0
GPER1 signaling R-HSA-9634597 9.243616e-02 1.034 0 0
Viral Messenger RNA Synthesis R-HSA-168325 7.627247e-02 1.118 0 0
Interleukin-1 signaling R-HSA-9020702 1.078991e-01 0.967 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 6.121703e-02 1.213 0 0
Signalling to ERKs R-HSA-187687 1.054870e-01 0.977 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 9.433958e-02 1.025 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 1.171183e-01 0.931 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 1.171183e-01 0.931 0 0
Downstream TCR signaling R-HSA-202424 6.328512e-02 1.199 0 0
MTOR signalling R-HSA-165159 6.390626e-02 1.194 0 0
CHL1 interactions R-HSA-447041 6.809085e-02 1.167 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 9.288142e-02 1.032 0 0
Regulation of PTEN gene transcription R-HSA-8943724 7.227844e-02 1.141 0 0
Hedgehog ligand biogenesis R-HSA-5358346 1.087819e-01 0.963 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 8.908792e-02 1.050 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 7.630080e-02 1.117 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 9.636706e-02 1.016 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 9.636706e-02 1.016 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 9.636706e-02 1.016 0 0
DAP12 interactions R-HSA-2172127 7.278270e-02 1.138 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.773551e-02 1.010 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.773551e-02 1.010 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 8.877419e-02 1.052 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 9.887609e-02 1.005 0 0
ARMS-mediated activation R-HSA-170984 9.288142e-02 1.032 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 9.999695e-02 1.000 0 0
Effects of PIP2 hydrolysis R-HSA-114508 9.243626e-02 1.034 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 8.018448e-02 1.096 0 0
Basigin interactions R-HSA-210991 9.999695e-02 1.000 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 7.336063e-02 1.135 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 8.018448e-02 1.096 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 9.288142e-02 1.032 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 8.621858e-02 1.064 0 0
tRNA processing in the nucleus R-HSA-6784531 8.038912e-02 1.095 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 8.755966e-02 1.058 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 5.972332e-02 1.224 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.061109e-01 0.974 0 0
Signaling by PDGFR in disease R-HSA-9671555 1.086999e-01 0.964 0 0
Assembly Of The HIV Virion R-HSA-175474 1.086999e-01 0.964 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 6.390626e-02 1.194 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.145236e-01 0.941 0 0
Regulation of TP53 Activity R-HSA-5633007 8.104017e-02 1.091 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 8.414031e-02 1.075 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.809085e-02 1.167 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 8.018448e-02 1.096 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 9.288142e-02 1.032 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 9.159029e-02 1.038 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 1.086999e-01 0.964 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 1.086999e-01 0.964 0 0
Triglyceride catabolism R-HSA-163560 1.123092e-01 0.950 0 0
Modulation by Mtb of host immune system R-HSA-9637628 8.018448e-02 1.096 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 7.572495e-02 1.121 0 0
Cellular response to chemical stress R-HSA-9711123 6.979324e-02 1.156 0 0
Pexophagy R-HSA-9664873 1.061109e-01 0.974 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 8.301454e-02 1.081 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 6.768466e-02 1.170 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 7.599877e-02 1.119 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.076184e-01 0.968 0 0
Glycogen synthesis R-HSA-3322077 9.159029e-02 1.038 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 9.243616e-02 1.034 0 0
FLT3 signaling in disease R-HSA-9682385 1.123092e-01 0.950 0 0
TRAF3 deficiency - HSE R-HSA-5602571 1.194911e-01 0.923 0 0
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) R-HSA-5619111 1.194911e-01 0.923 0 0
Defective PGM1 causes PGM1-CDG R-HSA-5609974 1.194911e-01 0.923 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.194911e-01 0.923 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.198069e-01 0.922 0 0
Interleukin-2 signaling R-HSA-9020558 1.198069e-01 0.922 0 0
ChREBP activates metabolic gene expression R-HSA-163765 1.198069e-01 0.922 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 1.212621e-01 0.916 0 0
Leishmania parasite growth and survival R-HSA-9664433 1.212621e-01 0.916 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 1.265179e-01 0.898 0 0
ER-Phagosome pathway R-HSA-1236974 1.269908e-01 0.896 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.280897e-01 0.892 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.287183e-01 0.890 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 1.288899e-01 0.890 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 1.288899e-01 0.890 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.318080e-01 0.880 0 0
G alpha (z) signalling events R-HSA-418597 1.325873e-01 0.877 0 0
Stabilization of p53 R-HSA-69541 1.338919e-01 0.873 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 1.338919e-01 0.873 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 1.338919e-01 0.873 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.339080e-01 0.873 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 1.339080e-01 0.873 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.339080e-01 0.873 0 0
Integration of provirus R-HSA-162592 1.339080e-01 0.873 0 0
NF-kB is activated and signals survival R-HSA-209560 1.339080e-01 0.873 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 1.339080e-01 0.873 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 1.364331e-01 0.865 0 0
TNF signaling R-HSA-75893 1.388772e-01 0.857 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 1.388772e-01 0.857 0 0
Signaling by NOTCH4 R-HSA-9013694 1.389813e-01 0.857 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 1.414370e-01 0.849 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 1.414370e-01 0.849 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 1.414370e-01 0.849 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 1.414370e-01 0.849 0 0
Diseases of Immune System R-HSA-5260271 1.414370e-01 0.849 0 0
Glycogen metabolism R-HSA-8982491 1.414370e-01 0.849 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.452956e-01 0.838 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 1.461671e-01 0.835 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 1.461671e-01 0.835 0 0
HDMs demethylate histones R-HSA-3214842 1.461671e-01 0.835 0 0
Tight junction interactions R-HSA-420029 1.461671e-01 0.835 0 0
Interleukin-7 signaling R-HSA-1266695 1.461671e-01 0.835 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 1.467152e-01 0.834 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.483570e-01 0.829 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.483570e-01 0.829 0 0
GRB2 events in EGFR signaling R-HSA-179812 1.483570e-01 0.829 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 1.483570e-01 0.829 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 1.483570e-01 0.829 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 1.483570e-01 0.829 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 1.483570e-01 0.829 0 0
IRAK1 recruits IKK complex R-HSA-937039 1.483570e-01 0.829 0 0
p75NTR recruits signalling complexes R-HSA-209543 1.483570e-01 0.829 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 1.491463e-01 0.826 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 1.491463e-01 0.826 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 1.491463e-01 0.826 0 0
Post-translational protein modification R-HSA-597592 1.512012e-01 0.820 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.514532e-01 0.820 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.514532e-01 0.820 0 0
FCGR activation R-HSA-2029481 1.518615e-01 0.819 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 1.560642e-01 0.807 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 1.560642e-01 0.807 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 1.560642e-01 0.807 0 0
Potassium transport channels R-HSA-1296067 1.560642e-01 0.807 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.560642e-01 0.807 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 1.560642e-01 0.807 0 0
Regulation of cortical dendrite branching R-HSA-8985801 1.560642e-01 0.807 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 1.560642e-01 0.807 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 1.561196e-01 0.807 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 1.561196e-01 0.807 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 1.561196e-01 0.807 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.631010e-01 0.788 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.631010e-01 0.788 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 1.631010e-01 0.788 0 0
Frs2-mediated activation R-HSA-170968 1.631010e-01 0.788 0 0
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis R-HSA-9029558 1.631010e-01 0.788 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 1.631010e-01 0.788 0 0
RAB geranylgeranylation R-HSA-8873719 1.652847e-01 0.782 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 1.662753e-01 0.779 0 0
Sensory processing of sound R-HSA-9659379 1.679877e-01 0.775 0 0
Extracellular matrix organization R-HSA-1474244 1.702971e-01 0.769 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 1.731905e-01 0.761 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.731905e-01 0.761 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 1.766184e-01 0.753 0 0
Pyroptosis R-HSA-5620971 1.766184e-01 0.753 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 1.766184e-01 0.753 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 1.780905e-01 0.749 0 0
CRMPs in Sema3A signaling R-HSA-399956 1.780905e-01 0.749 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.780905e-01 0.749 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 1.780905e-01 0.749 0 0
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA R-HSA-77310 1.780905e-01 0.749 0 0
Beta oxidation of hexanoyl-CoA to butanoyl-CoA R-HSA-77350 1.780905e-01 0.749 0 0
Beta oxidation of octanoyl-CoA to hexanoyl-CoA R-HSA-77348 1.780905e-01 0.749 0 0
NRIF signals cell death from the nucleus R-HSA-205043 1.780905e-01 0.749 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 1.780905e-01 0.749 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 1.780905e-01 0.749 0 0
Acyl chain remodeling of CL R-HSA-1482798 1.780905e-01 0.749 0 0
Signal regulatory protein family interactions R-HSA-391160 1.780905e-01 0.749 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.788045e-01 0.748 0 0
Mitochondrial protein import R-HSA-1268020 1.791829e-01 0.747 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.791829e-01 0.747 0 0
Signaling by PDGF R-HSA-186797 1.791829e-01 0.747 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 1.802505e-01 0.744 0 0
Potential therapeutics for SARS R-HSA-9679191 1.814341e-01 0.741 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 1.814868e-01 0.741 0 0
Post-translational protein phosphorylation R-HSA-8957275 1.844230e-01 0.734 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 1.862913e-01 0.730 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 1.862913e-01 0.730 0 0
Signaling by Erythropoietin R-HSA-9006335 1.871338e-01 0.728 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 1.871338e-01 0.728 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 1.899118e-01 0.721 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 1.899118e-01 0.721 0 0
Interleukin-1 family signaling R-HSA-446652 1.904488e-01 0.720 0 0
FasL/ CD95L signaling R-HSA-75157 1.911204e-01 0.719 0 0
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins R-HSA-9673766 1.911204e-01 0.719 0 0
IRAK4 deficiency (TLR5) R-HSA-5603037 1.911204e-01 0.719 0 0
Classical Kir channels R-HSA-1296053 1.911204e-01 0.719 0 0
MET interacts with TNS proteins R-HSA-8875513 1.911204e-01 0.719 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.932798e-01 0.714 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.932798e-01 0.714 0 0
Translesion synthesis by REV1 R-HSA-110312 1.932798e-01 0.714 0 0
p38MAPK events R-HSA-171007 1.932798e-01 0.714 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.932798e-01 0.714 0 0
p75NTR signals via NF-kB R-HSA-193639 1.932798e-01 0.714 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 1.935003e-01 0.713 0 0
Ion transport by P-type ATPases R-HSA-936837 1.935003e-01 0.713 0 0
Mitochondrial biogenesis R-HSA-1592230 1.967761e-01 0.706 0 0
Regulation of TNFR1 signaling R-HSA-5357905 1.984581e-01 0.702 0 0
Integration of energy metabolism R-HSA-163685 2.063133e-01 0.685 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 2.086209e-01 0.681 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 2.086209e-01 0.681 0 0
Translesion synthesis by POLI R-HSA-5656121 2.086266e-01 0.681 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 2.086266e-01 0.681 0 0
Prolonged ERK activation events R-HSA-169893 2.086266e-01 0.681 0 0
Regulation of BACH1 activity R-HSA-9708530 2.086266e-01 0.681 0 0
NGF-stimulated transcription R-HSA-9031628 2.158854e-01 0.666 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 2.190240e-01 0.660 0 0
PTEN Regulation R-HSA-6807070 2.216461e-01 0.654 0 0
Translesion synthesis by POLK R-HSA-5655862 2.240917e-01 0.650 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 2.240917e-01 0.650 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 2.240917e-01 0.650 0 0
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA R-HSA-77346 2.240917e-01 0.650 0 0
Galactose catabolism R-HSA-70370 2.240917e-01 0.650 0 0
Response to metal ions R-HSA-5660526 2.240917e-01 0.650 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 2.247224e-01 0.648 0 0
HCN channels R-HSA-1296061 2.247224e-01 0.648 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 2.247224e-01 0.648 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 2.247224e-01 0.648 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 2.247224e-01 0.648 0 0
Regulation of gap junction activity R-HSA-191650 2.247224e-01 0.648 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.247224e-01 0.648 0 0
Dopamine receptors R-HSA-390651 2.247224e-01 0.648 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.247224e-01 0.648 0 0
NADE modulates death signalling R-HSA-205025 2.247224e-01 0.648 0 0
Pyruvate metabolism R-HSA-70268 2.257455e-01 0.646 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 2.306189e-01 0.637 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 2.306189e-01 0.637 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 2.379504e-01 0.624 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 2.396387e-01 0.620 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 2.396387e-01 0.620 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 2.396387e-01 0.620 0 0
Specification of primordial germ cells R-HSA-9827857 2.396387e-01 0.620 0 0
Glycogen storage diseases R-HSA-3229121 2.396387e-01 0.620 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.417740e-01 0.617 0 0
Vpu mediated degradation of CD4 R-HSA-180534 2.417740e-01 0.617 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 2.417740e-01 0.617 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 2.464112e-01 0.608 0 0
Regulation of mitotic cell cycle R-HSA-453276 2.464112e-01 0.608 0 0
Hedgehog 'on' state R-HSA-5632684 2.464112e-01 0.608 0 0
G1/S Transition R-HSA-69206 2.468988e-01 0.607 0 0
Antigen processing-Cross presentation R-HSA-1236975 2.505440e-01 0.601 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 2.518729e-01 0.599 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 2.518729e-01 0.599 0 0
Orc1 removal from chromatin R-HSA-68949 2.518729e-01 0.599 0 0
NOD1/2 Signaling Pathway R-HSA-168638 2.530151e-01 0.597 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 2.530151e-01 0.597 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 2.530151e-01 0.597 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 2.542662e-01 0.595 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 2.552344e-01 0.593 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.552344e-01 0.593 0 0
Polo-like kinase mediated events R-HSA-156711 2.552344e-01 0.593 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.552344e-01 0.593 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.552344e-01 0.593 0 0
IRS activation R-HSA-74713 2.569305e-01 0.590 0 0
G2 Phase R-HSA-68911 2.569305e-01 0.590 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 2.569305e-01 0.590 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.569305e-01 0.590 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 2.569305e-01 0.590 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.569305e-01 0.590 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.569305e-01 0.590 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.569305e-01 0.590 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.569305e-01 0.590 0 0
Reelin signalling pathway R-HSA-8866376 2.569305e-01 0.590 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.569305e-01 0.590 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.569305e-01 0.590 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 2.610635e-01 0.583 0 0
Ca2+ pathway R-HSA-4086398 2.621818e-01 0.581 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.621818e-01 0.581 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 2.643289e-01 0.578 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 2.643289e-01 0.578 0 0
Regulation of Apoptosis R-HSA-169911 2.643289e-01 0.578 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 2.703173e-01 0.568 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.708479e-01 0.567 0 0
The NLRP3 inflammasome R-HSA-844456 2.708479e-01 0.567 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 2.744755e-01 0.561 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.757026e-01 0.560 0 0
G1/S-Specific Transcription R-HSA-69205 2.757026e-01 0.560 0 0
RUNX2 regulates bone development R-HSA-8941326 2.757026e-01 0.560 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.796273e-01 0.553 0 0
Signaling by NOTCH3 R-HSA-9012852 2.796273e-01 0.553 0 0
Collagen formation R-HSA-1474290 2.816398e-01 0.550 0 0
Toll-like Receptor Cascades R-HSA-168898 2.822008e-01 0.549 0 0
UCH proteinases R-HSA-5689603 2.862476e-01 0.543 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 2.864509e-01 0.543 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.864509e-01 0.543 0 0
Protein hydroxylation R-HSA-9629569 2.864509e-01 0.543 0 0
Formation of definitive endoderm R-HSA-9823730 2.864509e-01 0.543 0 0
Degradation of DVL R-HSA-4641258 2.871239e-01 0.542 0 0
Degradation of AXIN R-HSA-4641257 2.871239e-01 0.542 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 2.871239e-01 0.542 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 2.871239e-01 0.542 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.871239e-01 0.542 0 0
Plus-strand DNA synthesis R-HSA-164525 2.878025e-01 0.541 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.878025e-01 0.541 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.878025e-01 0.541 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.878025e-01 0.541 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.878025e-01 0.541 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.878025e-01 0.541 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.878025e-01 0.541 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.878025e-01 0.541 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.878025e-01 0.541 0 0
Phosphorylation of Emi1 R-HSA-176417 2.878025e-01 0.541 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.878025e-01 0.541 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.878025e-01 0.541 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.878025e-01 0.541 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.878025e-01 0.541 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.888455e-01 0.539 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.889867e-01 0.539 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 2.958729e-01 0.529 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 2.981673e-01 0.526 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 2.985808e-01 0.525 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 3.020173e-01 0.520 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 3.020173e-01 0.520 0 0
Signalling to RAS R-HSA-167044 3.020173e-01 0.520 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 3.020173e-01 0.520 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 3.020173e-01 0.520 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 3.020173e-01 0.520 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 3.020173e-01 0.520 0 0
ABC transporter disorders R-HSA-5619084 3.025131e-01 0.519 0 0
Protein localization R-HSA-9609507 3.038833e-01 0.517 0 0
Death Receptor Signaling R-HSA-73887 3.096251e-01 0.509 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.100619e-01 0.509 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 3.100619e-01 0.509 0 0
Plasma lipoprotein clearance R-HSA-8964043 3.100619e-01 0.509 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 3.172942e-01 0.499 0 0
Triglyceride metabolism R-HSA-8979227 3.172942e-01 0.499 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 3.172942e-01 0.499 0 0
Signaling by LTK in cancer R-HSA-9842640 3.173936e-01 0.498 0 0
Autointegration results in viral DNA circles R-HSA-177539 3.173936e-01 0.498 0 0
Uncoating of the HIV Virion R-HSA-162585 3.173936e-01 0.498 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 3.173936e-01 0.498 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 3.173936e-01 0.498 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 3.173936e-01 0.498 0 0
Integration of viral DNA into host genomic DNA R-HSA-175567 3.173936e-01 0.498 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.173936e-01 0.498 0 0
VLDL assembly R-HSA-8866423 3.173936e-01 0.498 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 3.175234e-01 0.498 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.175234e-01 0.498 0 0
Ribavirin ADME R-HSA-9755088 3.175234e-01 0.498 0 0
Regulation of insulin secretion R-HSA-422356 3.180206e-01 0.498 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 3.215559e-01 0.493 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 3.215559e-01 0.493 0 0
tRNA Aminoacylation R-HSA-379724 3.267848e-01 0.486 0 0
Fructose metabolism R-HSA-5652084 3.329472e-01 0.478 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 3.329472e-01 0.478 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 3.330523e-01 0.477 0 0
Asparagine N-linked glycosylation R-HSA-446203 3.332612e-01 0.477 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 3.360273e-01 0.474 0 0
MAP kinase activation R-HSA-450294 3.362922e-01 0.473 0 0
Degradation of CRY and PER proteins R-HSA-9932298 3.445408e-01 0.463 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.457569e-01 0.461 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.457569e-01 0.461 0 0
Recycling of eIF2:GDP R-HSA-72731 3.457569e-01 0.461 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.457569e-01 0.461 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.457569e-01 0.461 0 0
LDL remodeling R-HSA-8964041 3.457569e-01 0.461 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.457569e-01 0.461 0 0
Netrin mediated repulsion signals R-HSA-418886 3.457569e-01 0.461 0 0
Nef Mediated CD4 Down-regulation R-HSA-167590 3.457569e-01 0.461 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.457569e-01 0.461 0 0
NCAM signaling for neurite out-growth R-HSA-375165 3.458104e-01 0.461 0 0
Growth hormone receptor signaling R-HSA-982772 3.482690e-01 0.458 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.482690e-01 0.458 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 3.519949e-01 0.453 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 3.560117e-01 0.449 0 0
ADP signalling through P2Y purinoceptor 1 R-HSA-418592 3.634705e-01 0.440 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 3.634705e-01 0.440 0 0
Complex III assembly R-HSA-9865881 3.634705e-01 0.440 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 3.686073e-01 0.433 0 0
Amplification of signal from the kinetochores R-HSA-141424 3.686073e-01 0.433 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 3.686073e-01 0.433 0 0
Reverse Transcription of HIV RNA R-HSA-162589 3.729434e-01 0.428 0 0
Minus-strand DNA synthesis R-HSA-164516 3.729434e-01 0.428 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.729434e-01 0.428 0 0
phospho-PLA2 pathway R-HSA-111995 3.729434e-01 0.428 0 0
Nef mediated downregulation of MHC class I complex cell surface expression R-HSA-164940 3.729434e-01 0.428 0 0
Regulation by c-FLIP R-HSA-3371378 3.729434e-01 0.428 0 0
Activation of RAS in B cells R-HSA-1169092 3.729434e-01 0.428 0 0
Fructose biosynthesis R-HSA-5652227 3.729434e-01 0.428 0 0
Dimerization of procaspase-8 R-HSA-69416 3.729434e-01 0.428 0 0
Sodium/Proton exchangers R-HSA-425986 3.729434e-01 0.428 0 0
Interleukin-23 signaling R-HSA-9020933 3.729434e-01 0.428 0 0
Nucleotide Excision Repair R-HSA-5696398 3.774333e-01 0.423 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 3.785354e-01 0.422 0 0
Laminin interactions R-HSA-3000157 3.785354e-01 0.422 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 3.785354e-01 0.422 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 3.785354e-01 0.422 0 0
Fanconi Anemia Pathway R-HSA-6783310 3.902270e-01 0.409 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 3.902270e-01 0.409 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 3.902270e-01 0.409 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 3.902270e-01 0.409 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 3.902270e-01 0.409 0 0
Somitogenesis R-HSA-9824272 3.902270e-01 0.409 0 0
Metalloprotease DUBs R-HSA-5689901 3.934488e-01 0.405 0 0
Myogenesis R-HSA-525793 3.934488e-01 0.405 0 0
Suppression of phagosomal maturation R-HSA-9637687 3.934488e-01 0.405 0 0
CASP8 activity is inhibited R-HSA-5218900 3.990017e-01 0.399 0 0
ALK mutants bind TKIs R-HSA-9700645 3.990017e-01 0.399 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 3.990017e-01 0.399 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.990017e-01 0.399 0 0
Calcineurin activates NFAT R-HSA-2025928 3.990017e-01 0.399 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.990017e-01 0.399 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 3.990017e-01 0.399 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.990017e-01 0.399 0 0
Regulation of commissural axon pathfinding by SLIT and ROBO R-HSA-428542 3.990017e-01 0.399 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 3.990017e-01 0.399 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.990017e-01 0.399 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.990017e-01 0.399 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 3.990017e-01 0.399 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 4.015381e-01 0.396 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.015381e-01 0.396 0 0
Regulation of pyruvate metabolism R-HSA-9861718 4.015381e-01 0.396 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 4.015381e-01 0.396 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 4.028247e-01 0.395 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 4.058859e-01 0.392 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 4.081973e-01 0.389 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 4.081973e-01 0.389 0 0
Cristae formation R-HSA-8949613 4.081973e-01 0.389 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 4.081973e-01 0.389 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 4.081973e-01 0.389 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 4.081973e-01 0.389 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.127890e-01 0.384 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 4.127890e-01 0.384 0 0
Interleukin-17 signaling R-HSA-448424 4.216658e-01 0.375 0 0
HIV elongation arrest and recovery R-HSA-167287 4.227689e-01 0.374 0 0
Pausing and recovery of HIV elongation R-HSA-167290 4.227689e-01 0.374 0 0
Telomere Extension By Telomerase R-HSA-171319 4.227689e-01 0.374 0 0
Inflammasomes R-HSA-622312 4.227689e-01 0.374 0 0
Regulation of CDH11 function R-HSA-9762292 4.239787e-01 0.373 0 0
Formation of apoptosome R-HSA-111458 4.239787e-01 0.373 0 0
PI3K/AKT activation R-HSA-198203 4.239787e-01 0.373 0 0
Regulation of the apoptosome activity R-HSA-9627069 4.239787e-01 0.373 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 4.239787e-01 0.373 0 0
Signal attenuation R-HSA-74749 4.239787e-01 0.373 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 4.239787e-01 0.373 0 0
2-LTR circle formation R-HSA-164843 4.239787e-01 0.373 0 0
Sperm Motility And Taxes R-HSA-1300642 4.239787e-01 0.373 0 0
MAPK3 (ERK1) activation R-HSA-110056 4.239787e-01 0.373 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 4.239787e-01 0.373 0 0
Receptor Mediated Mitophagy R-HSA-8934903 4.239787e-01 0.373 0 0
Signaling by Leptin R-HSA-2586552 4.239787e-01 0.373 0 0
Cardiac conduction R-HSA-5576891 4.315465e-01 0.365 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 4.350818e-01 0.361 0 0
Termination of translesion DNA synthesis R-HSA-5656169 4.371528e-01 0.359 0 0
Platelet calcium homeostasis R-HSA-418360 4.371528e-01 0.359 0 0
Circadian clock R-HSA-9909396 4.383553e-01 0.358 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 4.403603e-01 0.356 0 0
Azathioprine ADME R-HSA-9748787 4.461104e-01 0.351 0 0
vRNP Assembly R-HSA-192905 4.479191e-01 0.349 0 0
Chylomicron assembly R-HSA-8963888 4.479191e-01 0.349 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 4.479191e-01 0.349 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 4.479191e-01 0.349 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.479191e-01 0.349 0 0
Switching of origins to a post-replicative state R-HSA-69052 4.496416e-01 0.347 0 0
Interleukin-37 signaling R-HSA-9008059 4.513395e-01 0.345 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 4.570523e-01 0.340 0 0
The phototransduction cascade R-HSA-2514856 4.570523e-01 0.340 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 4.653205e-01 0.332 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.653205e-01 0.332 0 0
Molecules associated with elastic fibres R-HSA-2129379 4.653205e-01 0.332 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 4.679018e-01 0.330 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 4.680521e-01 0.330 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.708659e-01 0.327 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.708659e-01 0.327 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 4.708659e-01 0.327 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 4.708659e-01 0.327 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 4.708659e-01 0.327 0 0
Sensing of DNA Double Strand Breaks R-HSA-5693548 4.708659e-01 0.327 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 4.708659e-01 0.327 0 0
Potassium Channels R-HSA-1296071 4.754981e-01 0.323 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 4.786535e-01 0.320 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.786535e-01 0.320 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.786535e-01 0.320 0 0
Inwardly rectifying K+ channels R-HSA-1296065 4.790885e-01 0.320 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 4.790885e-01 0.320 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 4.790885e-01 0.320 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.928603e-01 0.307 0 0
Beta oxidation of myristoyl-CoA to lauroyl-CoA R-HSA-77285 4.928603e-01 0.307 0 0
Beta oxidation of palmitoyl-CoA to myristoyl-CoA R-HSA-77305 4.928603e-01 0.307 0 0
MET activates RAS signaling R-HSA-8851805 4.928603e-01 0.307 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 4.928603e-01 0.307 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 4.928603e-01 0.307 0 0
OAS antiviral response R-HSA-8983711 4.928603e-01 0.307 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.994358e-01 0.302 0 0
FOXO-mediated transcription R-HSA-9614085 4.994358e-01 0.302 0 0
Glutamate and glutamine metabolism R-HSA-8964539 5.059605e-01 0.296 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 5.059605e-01 0.296 0 0
Mitotic Spindle Checkpoint R-HSA-69618 5.073229e-01 0.295 0 0
ABC-family proteins mediated transport R-HSA-382556 5.073229e-01 0.295 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 5.102742e-01 0.292 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 5.102742e-01 0.292 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 5.139417e-01 0.289 0 0
Processing of SMDT1 R-HSA-8949664 5.139417e-01 0.289 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 5.139417e-01 0.289 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 5.139417e-01 0.289 0 0
Interleukin-6 signaling R-HSA-1059683 5.139417e-01 0.289 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.139417e-01 0.289 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 5.151600e-01 0.288 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 5.190542e-01 0.285 0 0
Dual Incision in GG-NER R-HSA-5696400 5.190542e-01 0.285 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 5.190542e-01 0.285 0 0
Calnexin/calreticulin cycle R-HSA-901042 5.190542e-01 0.285 0 0
Signal amplification R-HSA-392518 5.190542e-01 0.285 0 0
Signaling by NOTCH2 R-HSA-1980145 5.190542e-01 0.285 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 5.190542e-01 0.285 0 0
Dectin-2 family R-HSA-5621480 5.205886e-01 0.284 0 0
Ion channel transport R-HSA-983712 5.214192e-01 0.283 0 0
Cell surface interactions at the vascular wall R-HSA-202733 5.290558e-01 0.276 0 0
Dual incision in TC-NER R-HSA-6782135 5.307837e-01 0.275 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 5.307837e-01 0.275 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 5.319143e-01 0.274 0 0
Oncogene Induced Senescence R-HSA-2559585 5.319143e-01 0.274 0 0
cGMP effects R-HSA-418457 5.341480e-01 0.272 0 0
Hydrolysis of LPC R-HSA-1483115 5.341480e-01 0.272 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 5.341480e-01 0.272 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 5.341480e-01 0.272 0 0
Malate-aspartate shuttle R-HSA-9856872 5.341480e-01 0.272 0 0
Zinc transporters R-HSA-435354 5.341480e-01 0.272 0 0
Signaling by FGFR4 in disease R-HSA-5655291 5.341480e-01 0.272 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.341480e-01 0.272 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 5.445376e-01 0.264 0 0
RNA Polymerase III Transcription R-HSA-74158 5.445376e-01 0.264 0 0
RSV-host interactions R-HSA-9833110 5.459655e-01 0.263 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 5.535155e-01 0.257 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 5.535155e-01 0.257 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.535155e-01 0.257 0 0
Beta oxidation of butanoyl-CoA to acetyl-CoA R-HSA-77352 5.535155e-01 0.257 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 5.535155e-01 0.257 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 5.535155e-01 0.257 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 5.535155e-01 0.257 0 0
Other semaphorin interactions R-HSA-416700 5.535155e-01 0.257 0 0
Voltage gated Potassium channels R-HSA-1296072 5.569215e-01 0.254 0 0
Collagen chain trimerization R-HSA-8948216 5.569215e-01 0.254 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.606218e-01 0.251 0 0
Aquaporin-mediated transport R-HSA-445717 5.606218e-01 0.251 0 0
Formation of paraxial mesoderm R-HSA-9793380 5.606218e-01 0.251 0 0
Elastic fibre formation R-HSA-1566948 5.690641e-01 0.245 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 5.690641e-01 0.245 0 0
MITF-M-dependent gene expression R-HSA-9856651 5.696988e-01 0.244 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.720789e-01 0.243 0 0
Phosphorylation of the APC/C R-HSA-176412 5.720789e-01 0.243 0 0
Phase 4 - resting membrane potential R-HSA-5576886 5.720789e-01 0.243 0 0
Killing mechanisms R-HSA-9664420 5.720789e-01 0.243 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.720789e-01 0.243 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 5.720789e-01 0.243 0 0
Fructose catabolism R-HSA-70350 5.720789e-01 0.243 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.720789e-01 0.243 0 0
Activation of SMO R-HSA-5635838 5.720789e-01 0.243 0 0
Attachment and Entry R-HSA-9678110 5.720789e-01 0.243 0 0
Disorders of transmembrane transporters R-HSA-5619115 5.795281e-01 0.237 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 5.809641e-01 0.236 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 5.898716e-01 0.229 0 0
Fibronectin matrix formation R-HSA-1566977 5.898716e-01 0.229 0 0
Biosynthesis of maresin-like SPMs R-HSA-9027307 5.898716e-01 0.229 0 0
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids R-HSA-77288 5.898716e-01 0.229 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.898716e-01 0.229 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 5.898716e-01 0.229 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 5.926206e-01 0.227 0 0
HIV Transcription Elongation R-HSA-167169 5.926206e-01 0.227 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 5.926206e-01 0.227 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 5.926206e-01 0.227 0 0
Interleukin-2 family signaling R-HSA-451927 5.926206e-01 0.227 0 0
Cellular response to hypoxia R-HSA-1234174 5.985656e-01 0.223 0 0
Inositol phosphate metabolism R-HSA-1483249 6.045918e-01 0.219 0 0
Elevation of cytosolic Ca2+ levels R-HSA-139853 6.069255e-01 0.217 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 6.069255e-01 0.217 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 6.069255e-01 0.217 0 0
Translation of Structural Proteins R-HSA-9683701 6.152025e-01 0.211 0 0
Apoptotic factor-mediated response R-HSA-111471 6.232713e-01 0.205 0 0
Platelet sensitization by LDL R-HSA-432142 6.232713e-01 0.205 0 0
Tie2 Signaling R-HSA-210993 6.232713e-01 0.205 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 6.232713e-01 0.205 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9679504 6.232713e-01 0.205 0 0
Signaling by TGFB family members R-HSA-9006936 6.297828e-01 0.201 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 6.389383e-01 0.195 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 6.389383e-01 0.195 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.389383e-01 0.195 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.389383e-01 0.195 0 0
STING mediated induction of host immune responses R-HSA-1834941 6.389383e-01 0.195 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.389383e-01 0.195 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 6.389480e-01 0.195 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 6.428791e-01 0.192 0 0
ECM proteoglycans R-HSA-3000178 6.513158e-01 0.186 0 0
Transcription of E2F targets under negative control by DREAM complex R-HSA-1362277 6.539546e-01 0.184 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 6.539546e-01 0.184 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 6.539546e-01 0.184 0 0
Creatine metabolism R-HSA-71288 6.539546e-01 0.184 0 0
Acyl chain remodelling of PI R-HSA-1482922 6.539546e-01 0.184 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 6.539546e-01 0.184 0 0
Pregnenolone biosynthesis R-HSA-196108 6.539546e-01 0.184 0 0
mitochondrial fatty acid beta-oxidation of saturated fatty acids R-HSA-77286 6.574583e-01 0.182 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 6.574583e-01 0.182 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.674240e-01 0.176 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.674240e-01 0.176 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 6.677594e-01 0.175 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.683474e-01 0.175 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.683474e-01 0.175 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.683474e-01 0.175 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 6.683474e-01 0.175 0 0
Acyl chain remodelling of PG R-HSA-1482925 6.683474e-01 0.175 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 6.720192e-01 0.173 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 6.757662e-01 0.170 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 6.821423e-01 0.166 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 6.821423e-01 0.166 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.821423e-01 0.166 0 0
Attachment and Entry R-HSA-9694614 6.821423e-01 0.166 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 6.836297e-01 0.165 0 0
FCERI mediated NF-kB activation R-HSA-2871837 6.837854e-01 0.165 0 0
Metal ion SLC transporters R-HSA-425410 6.866514e-01 0.163 0 0
tRNA processing R-HSA-72306 6.900650e-01 0.161 0 0
Signaling by NOTCH1 R-HSA-1980143 6.913502e-01 0.160 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.953643e-01 0.158 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 6.953643e-01 0.158 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 6.953643e-01 0.158 0 0
LDL clearance R-HSA-8964038 6.953643e-01 0.158 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.953643e-01 0.158 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.953643e-01 0.158 0 0
Translation of Replicase and Assembly of the Replication Transcription Complex R-HSA-9694676 6.953643e-01 0.158 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 6.959179e-01 0.157 0 0
Formation of the cornified envelope R-HSA-6809371 6.959326e-01 0.157 0 0
Translation of Structural Proteins R-HSA-9694635 6.989282e-01 0.156 0 0
Signaling by FGFR2 in disease R-HSA-5655253 7.049566e-01 0.152 0 0
S Phase R-HSA-69242 7.058071e-01 0.151 0 0
Integrin cell surface interactions R-HSA-216083 7.063641e-01 0.151 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 7.063641e-01 0.151 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 7.080370e-01 0.150 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 7.080370e-01 0.150 0 0
Biosynthesis of maresins R-HSA-9018682 7.080370e-01 0.150 0 0
Formation of the ureteric bud R-HSA-9830674 7.080370e-01 0.150 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 7.080370e-01 0.150 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 7.136586e-01 0.147 0 0
CYP2E1 reactions R-HSA-211999 7.201833e-01 0.143 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 7.201833e-01 0.143 0 0
Mitochondrial RNA degradation R-HSA-9836573 7.201833e-01 0.143 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 7.201833e-01 0.143 0 0
Interleukin-6 family signaling R-HSA-6783589 7.201833e-01 0.143 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 7.223623e-01 0.141 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.223623e-01 0.141 0 0
G alpha (i) signalling events R-HSA-418594 7.285009e-01 0.138 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.318250e-01 0.136 0 0
G protein gated Potassium channels R-HSA-1296059 7.318250e-01 0.136 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.318250e-01 0.136 0 0
Acyl chain remodelling of PS R-HSA-1482801 7.318250e-01 0.136 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.318250e-01 0.136 0 0
Hyaluronan degradation R-HSA-2160916 7.318250e-01 0.136 0 0
Fertilization R-HSA-1187000 7.318250e-01 0.136 0 0
Platelet homeostasis R-HSA-418346 7.366947e-01 0.133 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 7.414394e-01 0.130 0 0
Synthesis of DNA R-HSA-69239 7.425993e-01 0.129 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 7.429830e-01 0.129 0 0
TRP channels R-HSA-3295583 7.429830e-01 0.129 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 7.429830e-01 0.129 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 7.429830e-01 0.129 0 0
Adipogenesis R-HSA-9843745 7.464237e-01 0.127 0 0
Stimuli-sensing channels R-HSA-2672351 7.484027e-01 0.126 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 7.536774e-01 0.123 0 0
Insulin processing R-HSA-264876 7.536774e-01 0.123 0 0
Maturation of hRSV A proteins R-HSA-9828806 7.536774e-01 0.123 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.536774e-01 0.123 0 0
NRAGE signals death through JNK R-HSA-193648 7.545768e-01 0.122 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 7.608370e-01 0.119 0 0
Interferon gamma signaling R-HSA-877300 7.608787e-01 0.119 0 0
IRS-mediated signalling R-HSA-112399 7.621094e-01 0.118 0 0
G alpha (q) signalling events R-HSA-416476 7.639182e-01 0.117 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 7.639274e-01 0.117 0 0
Formation of the Early Elongation Complex R-HSA-113418 7.639274e-01 0.117 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.639274e-01 0.117 0 0
FCERI mediated MAPK activation R-HSA-2871796 7.706167e-01 0.113 0 0
mRNA Capping R-HSA-72086 7.737516e-01 0.111 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 7.737516e-01 0.111 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 7.737516e-01 0.111 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.737516e-01 0.111 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 7.737516e-01 0.111 0 0
Peroxisomal protein import R-HSA-9033241 7.765747e-01 0.110 0 0
Extension of Telomeres R-HSA-180786 7.765747e-01 0.110 0 0
Activation of the pre-replicative complex R-HSA-68962 7.831674e-01 0.106 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.831674e-01 0.106 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 7.831674e-01 0.106 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.831674e-01 0.106 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.831674e-01 0.106 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 7.831674e-01 0.106 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.831674e-01 0.106 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.831674e-01 0.106 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 7.835148e-01 0.106 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 7.835148e-01 0.106 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 7.835148e-01 0.106 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 7.835148e-01 0.106 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 7.835148e-01 0.106 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 7.902649e-01 0.102 0 0
SLC transporter disorders R-HSA-5619102 7.959045e-01 0.099 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 7.961862e-01 0.099 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 8.008415e-01 0.096 0 0
Diseases of mitotic cell cycle R-HSA-9675126 8.008415e-01 0.096 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 8.032101e-01 0.095 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 8.068315e-01 0.093 0 0
Nuclear RNA decay R-HSA-9930044 8.091314e-01 0.092 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 8.091314e-01 0.092 0 0
Activation of ATR in response to replication stress R-HSA-176187 8.091314e-01 0.092 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 8.091314e-01 0.092 0 0
Diseases associated with glycosylation precursor biosynthesis R-HSA-5609975 8.091314e-01 0.092 0 0
Insulin receptor signalling cascade R-HSA-74751 8.094129e-01 0.092 0 0
IGF1R signaling cascade R-HSA-2428924 8.094129e-01 0.092 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 8.154408e-01 0.089 0 0
G alpha (s) signalling events R-HSA-418555 8.157106e-01 0.088 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.170768e-01 0.088 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 8.170768e-01 0.088 0 0
Vitamin B5 (pantothenate) metabolism R-HSA-199220 8.170768e-01 0.088 0 0
EGR2 and SOX10-mediated initiation of Schwann cell myelination R-HSA-9619665 8.170768e-01 0.088 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 8.237847e-01 0.084 0 0
eNOS activation R-HSA-203615 8.246919e-01 0.084 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 8.246919e-01 0.084 0 0
Hyaluronan metabolism R-HSA-2142845 8.246919e-01 0.084 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 8.269874e-01 0.083 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 8.316199e-01 0.080 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.319904e-01 0.080 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 8.319904e-01 0.080 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 8.319904e-01 0.080 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 8.319904e-01 0.080 0 0
PERK regulates gene expression R-HSA-381042 8.319904e-01 0.080 0 0
Transcription of the HIV genome R-HSA-167172 8.325136e-01 0.080 0 0
Gastrulation R-HSA-9758941 8.358773e-01 0.078 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 8.380220e-01 0.077 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 8.389855e-01 0.076 0 0
FGFR2 mutant receptor activation R-HSA-1839126 8.389855e-01 0.076 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 8.582736e-01 0.066 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.582736e-01 0.066 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 8.582736e-01 0.066 0 0
Signaling by ALK R-HSA-201556 8.582736e-01 0.066 0 0
Signaling by FGFR in disease R-HSA-1226099 8.624448e-01 0.064 0 0
ROS and RNS production in phagocytes R-HSA-1222556 8.624448e-01 0.064 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 8.641759e-01 0.063 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.641759e-01 0.063 0 0
Iron uptake and transport R-HSA-917937 8.669296e-01 0.062 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 8.698326e-01 0.061 0 0
Maturation of spike protein R-HSA-9694548 8.698326e-01 0.061 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.752542e-01 0.058 0 0
HIV Transcription Initiation R-HSA-167161 8.752542e-01 0.058 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.752542e-01 0.058 0 0
Intra-Golgi traffic R-HSA-6811438 8.752542e-01 0.058 0 0
Signaling by FGFR1 in disease R-HSA-5655302 8.752542e-01 0.058 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 8.754988e-01 0.058 0 0
Nuclear Receptor transcription pathway R-HSA-383280 8.795900e-01 0.056 0 0
G alpha (12/13) signalling events R-HSA-416482 8.795900e-01 0.056 0 0
Activation of GABAB receptors R-HSA-991365 8.804502e-01 0.055 0 0
GABA B receptor activation R-HSA-977444 8.804502e-01 0.055 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.804502e-01 0.055 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.854301e-01 0.053 0 0
TBC/RABGAPs R-HSA-8854214 8.854301e-01 0.053 0 0
Proteasome assembly R-HSA-9907900 8.902028e-01 0.051 0 0
Methylation R-HSA-156581 8.902028e-01 0.051 0 0
Amine ligand-binding receptors R-HSA-375280 8.902028e-01 0.051 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 8.947770e-01 0.048 0 0
Signaling by TGFBR3 R-HSA-9839373 8.991609e-01 0.046 0 0
Plasma lipoprotein remodeling R-HSA-8963899 9.073892e-01 0.042 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 9.111910e-01 0.040 0 0
Chemokine receptors bind chemokines R-HSA-380108 9.112483e-01 0.040 0 0
PI3K Cascade R-HSA-109704 9.149469e-01 0.039 0 0
Rab regulation of trafficking R-HSA-9007101 9.159049e-01 0.038 0 0
Neurexins and neuroligins R-HSA-6794361 9.218887e-01 0.035 0 0
Amino acids regulate mTORC1 R-HSA-9639288 9.251444e-01 0.034 0 0
Nucleotide biosynthesis R-HSA-8956320 9.251444e-01 0.034 0 0
Signaling by Insulin receptor R-HSA-74752 9.302068e-01 0.031 0 0
Paracetamol ADME R-HSA-9753281 9.312550e-01 0.031 0 0
Synthesis of PA R-HSA-1483166 9.368675e-01 0.028 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.371180e-01 0.028 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 9.413595e-01 0.026 0 0
Neddylation R-HSA-8951664 9.421786e-01 0.026 0 0
GABA receptor activation R-HSA-977443 9.444399e-01 0.025 0 0
Metabolism of polyamines R-HSA-351202 9.444399e-01 0.025 0 0
Sphingolipid de novo biosynthesis R-HSA-1660661 9.444399e-01 0.025 0 0
Collagen degradation R-HSA-1442490 9.467568e-01 0.024 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.489773e-01 0.023 0 0
Heme signaling R-HSA-9707616 9.489773e-01 0.023 0 0
Complex I biogenesis R-HSA-6799198 9.511052e-01 0.022 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.526020e-01 0.021 0 0
Xenobiotics R-HSA-211981 9.531446e-01 0.021 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.531446e-01 0.021 0 0
GPCR downstream signalling R-HSA-388396 9.535373e-01 0.021 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.558493e-01 0.020 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.569720e-01 0.019 0 0
Kidney development R-HSA-9830369 9.587670e-01 0.018 0 0
Metabolism of steroid hormones R-HSA-196071 9.587670e-01 0.018 0 0
Metabolism of nucleotides R-HSA-15869 9.602991e-01 0.018 0 0
Keratinization R-HSA-6805567 9.628060e-01 0.016 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.637156e-01 0.016 0 0
COPII-mediated vesicle transport R-HSA-204005 9.637156e-01 0.016 0 0
Metabolism of cofactors R-HSA-8978934 9.652296e-01 0.015 0 0
Respiratory electron transport R-HSA-611105 9.674874e-01 0.014 0 0
Aspirin ADME R-HSA-9749641 9.680710e-01 0.014 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.706805e-01 0.013 0 0
Visual phototransduction R-HSA-2187338 9.708993e-01 0.013 0 0
Peptide hormone metabolism R-HSA-2980736 9.750696e-01 0.011 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.752780e-01 0.011 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 9.772992e-01 0.010 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.791554e-01 0.009 0 0
Signaling by GPCR R-HSA-372790 9.805627e-01 0.009 0 0
Protein-protein interactions at synapses R-HSA-6794362 9.808601e-01 0.008 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.824255e-01 0.008 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.824255e-01 0.008 0 0
Neurotransmitter release cycle R-HSA-112310 9.851832e-01 0.006 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.884204e-01 0.005 0 0
Drug ADME R-HSA-9748784 9.907250e-01 0.004 0 0
Bacterial Infection Pathways R-HSA-9824439 9.908439e-01 0.004 0 0
PI Metabolism R-HSA-1483255 9.918499e-01 0.004 0 0
Peptide ligand-binding receptors R-HSA-375276 9.923155e-01 0.003 0 0
PPARA activates gene expression R-HSA-1989781 9.947373e-01 0.002 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.951200e-01 0.002 0 0
Transport of small molecules R-HSA-382551 9.979601e-01 0.001 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.981753e-01 0.001 0 0
Metabolism of steroids R-HSA-8957322 9.989312e-01 0.000 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 9.989543e-01 0.000 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.991958e-01 0.000 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.992253e-01 0.000 0 0
Arachidonate metabolism R-HSA-2142753 9.992890e-01 0.000 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 9.996263e-01 0.000 0 0
Diseases of glycosylation R-HSA-3781865 9.998275e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.998518e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.998828e-01 0.000 0 0
Sphingolipid metabolism R-HSA-428157 9.999169e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999600e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999680e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.999772e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.999791e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999813e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.999845e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999870e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999988e-01 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
GPCR ligand binding R-HSA-500792 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways