MST2

Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
Download
substrate_uniprot site source substrate_genes site_seq
A0MZ66 T455 Sugiyama SHTN1 KIAA1598 KPESSKGCEsAVDELKGILGtLNKSTSSRsLKsLDPENsEt
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 T949 Sugiyama POTEF A26C1B TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NMY6 S26 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI
A6NMY6 T163 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
O00571 T156 Sugiyama DDX3X DBX DDX3 WSKPLPPSERLEQELFsGGNtGINFEKYDDIPVEATGNNCP
O14818 S150 Sugiyama PSMA7 HSPC SALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVRE
O14818 T147 Sugiyama PSMA7 HSPC FGISALIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKS
O14818 T152 Sugiyama PSMA7 HSPC LIVGFDFDGTPRLyQtDPsGtyHAWKANAIGRGAKSVREFL
O14908 T238 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 FDMISQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPs
O14908 T242 Sugiyama GIPC1 C19orf3 GIPC RGS19IP1 SQRsAGGRPGsGPQLGtGRGtLRLRsRGPAtVEDLPsAFEE
O15143 S323 Sugiyama ARPC1B ARC41 QNLDKKAssEGGtAAGAGLDsLHKNsVsQIsVLsGGKAKCS
O15143 T315 Sugiyama ARPC1B ARC41 GLTARERFQNLDKKAssEGGtAAGAGLDsLHKNsVsQIsVL
O15523 T154 Sugiyama DDX3Y DBY WSKPLPPSERLEQELFsGGNtGINFEKYDDIPVEATGSNCP
O43290 T430 Sugiyama SART1 RKKEKEVVVRADDLLPLGDQtQDGDFGsRLRGRGRRRVsEV
O43390 T137 Sugiyama HNRNPR HNRPR ESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O43390 T141 Sugiyama HNRNPR HNRPR GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGVQP
O43707 S447 Sugiyama ACTN4 AWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAAHQ
O43707 S507 Sugiyama ACTN4 DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID
O43707 S511 Sugiyama ACTN4 VNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAIDQLHL
O43707 T249 Sugiyama ACTN4 EVAEKyLDIPKMLDAEDIVNtARPDEKAIMTyVssFyHAFs
O43707 T443 Sugiyama ACTN4 sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL
O43707 T445 Sugiyama ACTN4 HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA
O43852 T196 Sugiyama CALU FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD
O43852 T89 Sugiyama CALU sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV
O60271 T191 Sugiyama SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 MEHLERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPA
O60361 T88 Sugiyama NME2P1 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
O60506 T134 Sugiyama SYNCRIP HNRPQ NSAP1 DSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYS
O60506 T138 Sugiyama SYNCRIP HNRPQ NSAP1 GPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVYSGQQP
O60610 T545 Sugiyama DIAPH1 DIAP1 SEKQQIATEKQDLEAEVsQLtGEVAKLTKELEDAKKEMASL
O60716 T869 Sugiyama CTNND1 KIAA0384 FQVNLNNAsRsQssHsyDDstLPLIDRNQKsDKKPDREEIQ
O60841 S186 Sugiyama EIF5B IF2 KIAA0741 EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN
O60841 S222 Sugiyama EIF5B IF2 KIAA0741 KNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAEKKERERKK
O75369 T490 Sugiyama FLNB FLN1L FLN3 TABP TAP RETTDFKVDTKAAGSGELGVtMKGPKGLEELVKQKDFLDGV
O75821 S189 Sugiyama EIF3G EIF3S4 CPYKDtLGPMQKELAEQLGLstGEKEKLPGELEPVQAtQNK
O75821 T206 Sugiyama EIF3G EIF3S4 LGLstGEKEKLPGELEPVQAtQNKtGKYVPPsLRDGAsRRG
O75821 T210 Sugiyama EIF3G EIF3S4 tGEKEKLPGELEPVQAtQNKtGKYVPPsLRDGAsRRGESMQ
O75822 T157 Sugiyama EIF3J EIF3S1 PRO0391 GVNNAVyGIDAMNPSSRDDFtEFGKLLKDKITQYEKSLYYA
O94776 S433 Sugiyama MTA2 MTA1L1 PID ATRGtTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQt
O94776 Y437 Sugiyama MTA2 MTA1L1 PID tTEPHSRGHLsRPEAQsLsPyttsANRAKLLAKNRQtFLLQ
O95218 T100 Sugiyama ZRANB2 ZIS ZNF265 ARRsECNMCNtPKYAKLEERtGYGGGFNERENVEyIEREEs
O95373 T968 Sugiyama IPO7 RANBP7 IIDDEDNPVDEYQIFKAIFQtIQNRNPVWyQALTHGLNEEQ
O95373 T997 Sugiyama IPO7 RANBP7 yQALTHGLNEEQRKQLQDIAtLADQRRAAHESKMIEKHGGY
O95721 T139 Sugiyama SNAP29 LVNYFKSKPVEtPPEQNGtLtSQPNNRLKEAISTSKEQEAK
O95835 S872 EPSD|PSP LATS1 WARTS GFRWTHDSKYYQsGDHPRQDsMDFsNEWGDPSSCRCGDRLK
O95835 S909 GPS6|EPSD|PSP LATS1 WARTS DRLKPLERRAARQHQRCLAHsLVGTPNYIAPEVLLRTGYTQ
O95835 T1012 EPSD|PSP LATS1 WARTS PEDRLGKNGADEIKAHPFFKtIDFsSDLRQQSASYIPKITH
O95835 T1060 EPSD|PSP LATS1 WARTS DPVDPDKLWsDDNEEENVNDtLNGWYKNGKHPEHAFYEFtF
O95835 T1079 GPS6|EPSD|PSP LATS1 WARTS DtLNGWYKNGKHPEHAFYEFtFRRFFDDNGYPYNYPKPIEY
O95835 T967 EPSD|PSP LATS1 WARTS QPPFLAQTPLETQMKVINWQtSLHIPPQAKLSPEASDLIIK
O95861 T287 Sugiyama BPNT1 GNVLQYHKDVKHMNSAGVLAtLRNyDyyASRVPESIKNALV
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 S167 Sugiyama LDHA PIG19 AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG
P00491 T169 Sugiyama PNP NP GPNDERFGDRFPAMsDAyDRtMRQRALstWKQMGEQRELQE
P00519 T735 EPSD|PSP ABL1 ABL JTK7 RsCsAsCVPHGAKDTEWRSVtLPRDLQStGRQFDSstFGGH
P00558 S390 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 IIGGGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPG
P00558 S399 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__
P00558 T168 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF
P00558 T376 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MDEVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGG
P00558 T378 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 EVVKAtsRGCItIIGGGDtAtCCAKWNtEDKVsHVstGGGA
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P02545 S525 Sugiyama LMNA LMN1 tHsPPTDLVWKAQNtWGCGNsLRtALINstGEEVAMRKLVR
P02786 T143 Sugiyama TFRC yWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAGsQKDE
P02786 T362 Sugiyama TFRC AEKLFGNMEGDCPSDWKTDstCRMVTSESKNVKLTVSNVLK
P04040 S120 Sugiyama CAT FEHIGKKTPIAVRFStVAGEsGSADtVRDPRGFAVKFYTED
P04040 T125 Sugiyama CAT KKTPIAVRFStVAGEsGSADtVRDPRGFAVKFYTEDGNWDL
P04040 T434 Sugiyama CAT QQPSALEHSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEE
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 T119 Sugiyama ALDOA ALDA KsKGGVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYK
P04075 T123 Sugiyama ALDOA ALDA GVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGA
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04075 T52 Sugiyama ALDOA ALDA AADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDRVNP
P04083 T172 Sugiyama ANXA1 ANX1 LPC1 INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF
P04083 T223 Sugiyama ANXA1 ANX1 LPC1 ARALyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKY
P04083 T226 Sugiyama ANXA1 ANX1 LPC1 LyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKYSKH
P04150 S682 PSP NR3C1 GRL EYLCMKtLLLLSSVPKDGLKsQELFDEIRMTYIKELGKAIV
P04150 S746 PSP NR3C1 GRL HEVVENLLNYCFQTFLDKTMsIEFPEMLAEIITNQIPKYSN
P04150 T562 PSP NR3C1 GRL EVLYAGYDSSVPDStWRIMTtLNMLGGRQVIAAVKWAKAIP
P04150 T668 PSP NR3C1 GRL YVSSELHRLQVSYEEYLCMKtLLLLSSVPKDGLKsQELFDE
P04406 T246 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS
P05187 T185 Sugiyama ALPP PLAP VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC
P05455 S325 Sugiyama SSB VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA
P05783 T404 Sugiyama KRT18 CYK18 PIG46 LEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVVsETND
P05787 S291 Sugiyama KRT8 CYK8 ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN
P05787 S410 Sugiyama KRT8 CYK8 TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL
P05787 T413 Sugiyama KRT8 CYK8 KLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGLtsP
P06733 S291 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA
P06733 S353 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs
P06733 T100 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK
P06733 T19 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA
P06733 T205 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE
P06733 T26 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA
P06733 T41 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG
P06733 T55 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP
P06733 T72 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 NDKtRYMGKGVSKAVEHINKtIAPALVsKKLNVtEQEKIDK
P06744 T250 Sugiyama GPI LQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFWDWV
P06748 S260 Sugiyama NPM1 NPM GPssVEDIKAKMQAsIEKGGsLPKVEAKFINyVKNCFRMtD
P06748 S43 Sugiyama NPM1 NPM LKADKDyHFKVDNDENEHQLsLRTVsLGAGAKDELHIVEAE
P07108 T36 Sugiyama DBI LKTKPsDEEMLFIyGHyKQAtVGDINtERPGMLDFTGKAKW
P07108 T42 Sugiyama DBI DEEMLFIyGHyKQAtVGDINtERPGMLDFTGKAKWDAWNEL
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S168 Sugiyama LDHB TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG
P07195 T18 Sugiyama LDHB ___MATLKEKLIAPVAEEEAtVPNNKITVVGVGQVGMACAI
P07195 T276 Sugiyama LDHB SVADLIESMLKNLSRIHPVStMVKGMYGIENEVFLSLPCIL
P07195 T323 Sugiyama LDHB sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________
P07205 S390 Sugiyama PGK2 PGKB VIGGGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPG
P07205 S399 Sugiyama PGK2 PGKB CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__
P07205 T168 Sugiyama PGK2 PGKB EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 T85 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB KAAGKLKAEGSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFF
P07355 S26 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI
P07355 T163 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG
P07737 S85 Sugiyama PFN1 tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 T1506 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 LCELQPGAKCVCGKNPAKyytLFGRsy______________
P07858 T218 Sugiyama CTSB CPSB CTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSEKD
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07864 S167 Sugiyama LDHC LDH3 LDHX VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG
P07900 S476 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900 S63 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P07900 S641 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD
P07900 S72 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQDRtLtIV
P07900 T109 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LtIVDtGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
P07900 T171 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILHLK
P07900 T195 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG
P07900 T467 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN
P07900 T540 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yMIEPIDEyCVQQLKEFEGKtLVsVTKEGLELPEDEEEKKK
P07900 T624 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA yGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIE
P07900 T645 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL
P07900 Y493 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK
P08195 S253 Sugiyama SLC3A2 MDU1 FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S58 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238 S67 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB AsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERtLtLV
P08238 T104 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LtLVDtGIGMtKADLINNLGtIAKSGtKAFMEALQAGADIS
P08238 T166 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILHLK
P08238 T190 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 T616 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE
P08238 T637 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MGyMMAKKHLEINPDHPIVEtLRQKAEADKNDKAVKDLVVL
P08238 Y457 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK
P08238 Y619 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR
P08708 T30 Sugiyama RPS17 RPS17L KKAARVIIEKyytRLGNDFHtNKRVCEEIAIIPSKKLRNKI
P08758 S37 Sugiyama ANXA5 ANX5 ENX2 PP4 ERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAF
P08758 T23 Sugiyama ANXA5 ANX5 ENX2 PP4 QVLRGtVtDFPGFDERADAEtLRKAMKGLGtDEEsILtLLt
P08758 T33 Sugiyama ANXA5 ANX5 ENX2 PP4 PGFDERADAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEI
P08758 T40 Sugiyama ANXA5 ANX5 ENX2 PP4 DAEtLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTL
P08758 T43 Sugiyama ANXA5 ANX5 ENX2 PP4 tLRKAMKGLGtDEEsILtLLtsRsNAQRQEISAAFKTLFGR
P08865 T94 Sugiyama RPSA LAMBR LAMR1 VsVIssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQA
P08865 T97 Sugiyama RPSA LAMBR LAMR1 IssRNtGQRAVLKFAAAtGAtPIAGRFtPGTFTNQIQAAFR
P09104 T41 Sugiyama ENO2 EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG
P09211 T62 Sugiyama GSTP1 FAEES3 GST3 GsLKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGK
P09211 T68 Sugiyama GSTP1 FAEES3 GST3 CLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQQEAA
P09211 Y64 Sugiyama GSTP1 FAEES3 GST3 LKASCLyGQLPKFQDGDLtLyQsNtILRHLGRTLGLYGKDQ
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P09382 T58 Sugiyama LGALS1 DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF
P09429 S35 Sugiyama HMGB1 HMG1 syAFFVQtCREEHKKKHPDAsVNFsEFsKKCsERWKtMsAK
P09651 S365 Sugiyama HNRNPA1 HNRPA1 GQyFAKPRNQGGyGGssssssyGsGRRF_____________
P09661 T213 Sugiyama SNRPA1 KGGPsPGDVEAIKNAIANAstLAEVERLKGLLQsGQIPGRE
P09923 T182 Sugiyama ALPI VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC
P09972 T124 Sugiyama ALDOC ALDC VVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGAD
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0DPH7 T334 Sugiyama TUBA3C TUBA2 ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
P0DPH7 T337 Sugiyama TUBA3C TUBA2 MLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
P0DPH7 T51 Sugiyama TUBA3C TUBA2 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P0DPH7 T56 Sugiyama TUBA3C TUBA2 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
P10412 S55 Sugiyama H1-4 H1F4 HIST1H1E AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P10768 T205 Sugiyama ESD KKAFsGyLGTDQsKWKAyDAtHLVKsYPGsQLDILIDQGKD
P10809 S67 Sugiyama HSPD1 HSP60 LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK
P10809 T113 Sugiyama HSPD1 HSP60 IGAKLVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISK
P10809 T117 Sugiyama HSPD1 HSP60 LVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISKGANP
P10809 T231 Sugiyama HSPD1 HSP60 LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI
P10809 T320 Sugiyama HSPD1 HSP60 VKAPGFGDNRKNQLKDMAIAtGGAVFGEEGLtLNLEDVQPH
P10809 T331 Sugiyama HSPD1 HSP60 NQLKDMAIAtGGAVFGEEGLtLNLEDVQPHDLGKVGEVIVt
P10809 T61 Sugiyama HSPD1 HSP60 LQGVDLLADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVA
P10809 Y223 Sugiyama HSPD1 HSP60 DGKtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAy
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 S432 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMTKD
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 T226 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK
P11142 T37 Sugiyama HSPA8 HSC70 HSP73 HSPA10 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P11142 T45 Sugiyama HSPA8 HSC70 HSP73 HSPA10 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN
P11142 T47 Sugiyama HSPA8 HSC70 HSP73 HSPA10 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtNtV
P11142 T586 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DKQKILDKCNEIINWLDKNQtAEKEEFEHQQKELEKVCNPI
P11142 T64 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ
P11142 T66 Sugiyama HSPA8 HSC70 HSP73 HSPA10 DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD
P11766 T127 Sugiyama ADH5 ADHX FDH KTNLCQKIRVTQGKGLMPDGtSRFTCKGKTILHYMGTSTFS
P11940 T191 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 GRFKSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLF
P11940 T319 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KNLDDGIDDERLRKEFsPFGtItsAKVMMEGGRSKGFGFVC
P12268 S416 Sugiyama IMPDH2 IMPD2 APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK
P12277 S129 Sugiyama CKB CKBB DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG
P12956 T316 Sugiyama XRCC6 G22P1 VKTKTRtFNtstGGLLLPsDtKRSQIYGSRQIILEKEETEE
P13489 T176 Sugiyama RNH1 PRI RNH AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD
P13639 T484 Sugiyama EEF2 EF2 VPCGNIVGLVGVDQFLVKtGtIttFEHAHNMRVMKFsVsPV
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13667 S567 Sugiyama PDIA4 ERP70 ERP72 LIEFYAPWCGHCKQLEPVyNsLAKKYKGQKGLVIAKMDATA
P13667 T123 Sugiyama PDIA4 ERP70 ERP72 KIANILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKIL
P13667 T238 Sugiyama PDIA4 ERP70 ERP72 KAAKELSKRSPPIPLAKVDAtAETDLAKRFDVsGyPTLKIF
P13667 T380 Sugiyama PDIA4 ERP70 ERP72 PEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGHR
P13667 T497 Sugiyama PDIA4 ERP70 ERP72 AILDEsGKKFAMEPEEFDsDtLREFVtAFKKGKLKPVIKSQ
P13667 T503 Sugiyama PDIA4 ERP70 ERP72 GKKFAMEPEEFDsDtLREFVtAFKKGKLKPVIKSQPVPKNN
P13674 T147 Sugiyama P4HA1 P4HA QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC
P13929 T19 Sugiyama ENO3 __MAMQKIFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGA
P13929 T26 Sugiyama ENO3 IFAREILDsRGNPtVEVDLHtAKGRFRAAVPsGAstGIyEA
P13929 T41 Sugiyama ENO3 EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG
P13987 T76 Sugiyama CD59 MIC11 MIN1 MIN2 MIN3 MSK21 AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF
P14314 S445 Sugiyama PRKCSH G19P1 YRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKy
P14314 S451 Sugiyama PRKCSH G19P1 KLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMKyEQGtGC
P14314 T444 Sugiyama PRKCSH G19P1 VYRLCPFKLVSQKPKLGGsPtsLGtWGsWIGPDHDKFSAMK
P14314 T469 Sugiyama PRKCSH G19P1 WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S77 Sugiyama PKM OIP3 PK2 PK3 PKM2 sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs
P14618 T41 Sugiyama PKM OIP3 PK2 PK3 PKM2 AMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtL
P14618 T45 Sugiyama PKM OIP3 PK2 PK3 PKM2 TFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMI
P14618 T454 Sugiyama PKM OIP3 PK2 PK3 PKM2 SGRSAHQVARYRPRAPIIAVtRNPQtARQAHLYRGIFPVLC
P14618 T459 Sugiyama PKM OIP3 PK2 PK3 PKM2 HQVARYRPRAPIIAVtRNPQtARQAHLYRGIFPVLCKDPVQ
P14618 T50 Sugiyama PKM OIP3 PK2 PK3 PKM2 MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN
P14618 T87 Sugiyama PKM OIP3 PK2 PK3 PKM2 sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP
P14625 S680 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 RIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDMLRR
P14625 T148 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GNEELTVKIKCDKEKNLLHVtDtGVGMtREELVKNLGTIAK
P14625 T155 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 KIKCDKEKNLLHVtDtGVGMtREELVKNLGTIAKsGtsEFL
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P15170 T315 Sugiyama GSPT1 ERF3A NRSVDGPIRLPIVDKYKDMGtVVLGKLESGSICKGQQLVMM
P15259 S189 Sugiyama PGAM2 PGAMM EEIVPQIKAGKRVLIAAHGNsLRGIVKHLEGMSDQAIMELN
P15311 T299 Sugiyama EZR VIL2 RILQLCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQLE
P15311 T533 Sugiyama EZR VIL2 NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII
P15531 T103 Sugiyama NME1 NDPKA NM23 VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P15880 S190 Sugiyama RPS2 RPS4 WGNKIGKPHTVPCKVTGRCGsVLVRLIPAPRGtGIVsAPVP
P15880 T232 Sugiyama RPS2 RPS4 KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt
P15880 T285 Sugiyama RPS2 RPS4 PyQEFtDHLVKtHtRVsVQRtQAPAVATt____________
P15924 T61 Sugiyama DSP YYSRRGVITDQNsDGyCQtGtMsRHQNQNTIQELLQNCSDC
P16070 T76 Sugiyama CD44 LHR MDU2 MDU3 MIC4 FNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRIHPNSI
P16402 S56 Sugiyama H1-3 H1F3 HIST1H1D AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P16403 S55 Sugiyama H1-2 H1F2 HIST1H1C AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK
P17066 T228 Sugiyama HSPA6 HSP70B' DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P17066 T47 Sugiyama HSPA6 HSP70B' RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P17066 T49 Sugiyama HSPA6 HSP70B' EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P17252 S226 EPSD|PSP PRKCA PKCA PRKACA NESKQKTKTIRSTLNPQWNEsFtFKLKPSDKDRRLsVEIWD
P17252 T228 EPSD|PSP PRKCA PKCA PRKACA SKQKTKTIRSTLNPQWNEsFtFKLKPSDKDRRLsVEIWDWD
P17844 S520 Sugiyama DDX5 G17P1 HELR HLR1 GKRGGFNTFRDRENYDRGYssLLKRDFGAKTQNGVYSAANY
P17980 T163 Sugiyama PSMC3 TBP1 EKLKPGDLVGVNKDSyLILEtLPtEyDsRVKAMEVDERPtE
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18124 T17 Sugiyama RPL7 ____MEGVEEKKKEVPAVPEtLKKKRRNFAELKIKRLRKKF
P18621 S14 Sugiyama RPL17 _______MVRysLDPENPtKsCKSRGSNLRVHFKNtRETAQ
P18621 T12 Sugiyama RPL17 _________MVRysLDPENPtKsCKSRGSNLRVHFKNtRET
P18669 S155 Sugiyama PGAM1 PGAMA CDABP0006 NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI
P18669 S189 Sugiyama PGAM1 PGAMA CDABP0006 EEIVPQIKEGKRVLIAAHGNsLRGIVKHLEGLSEEAIMELN
P18669 T146 Sugiyama PGAM1 PGAMA CDABP0006 MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF
P18669 T159 Sugiyama PGAM1 PGAMA CDABP0006 DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 T301 Sugiyama NCL KKEMAKQKAAPEAKKQKVEGtEPttAFNLFVGNLNFNKSAP
P19338 T304 Sugiyama NCL MAKQKAAPEAKKQKVEGtEPttAFNLFVGNLNFNKSAPELK
P19338 T305 Sugiyama NCL AKQKAAPEAKKQKVEGtEPttAFNLFVGNLNFNKSAPELKt
P19338 T487 Sugiyama NCL KGQNQDYRGGKNSTWsGESKtLVLsNLsysAtEEtLQEVFE
P19338 T587 Sugiyama NCL RSQPSKTLFVKGLsEDttEEtLKEsFDGsVRARIVTDRETG
P19338 Y463 Sugiyama NCL EKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWsG
P20073 T203 Sugiyama ANXA7 ANX7 SNX OK/SW-cl.95 ANFDAIRDAEILRKAMKGFGtDEQAIVDVVANRsNDQRQKI
P20290 T131 Sugiyama BTF3 NACB OK/SW-cl.8 NQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsIL
P20290 T133 Sugiyama BTF3 NACB OK/SW-cl.8 GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ
P20290 T135 Sugiyama BTF3 NACB OK/SW-cl.8 VIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLG
P20290 T140 Sugiyama BTF3 NACB OK/SW-cl.8 NPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLGADsLt
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P20618 S162 Sugiyama PSMB1 PSC5 DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG
P22102 T39 Sugiyama GART PGFT PRGS WKLAQSHHVKQVLVAPGNAGtACSEKISNTAISISDHTALA
P22314 T676 Sugiyama UBA1 A1S9T UBE1 FKQPAENVNQyLtDPKFVERtLRLAGtQPLEVLEAVQRSLV
P22392 T103 Sugiyama NME2 NM23B VVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHGsDsV
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P22626 T140 Sugiyama HNRNPA2B1 HNRPA2B1 KEDTEEHHLRDyFEEYGKIDtIEIItDRQsGKKRGFGFVtF
P23246 S283 Sugiyama SFPQ PSF GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN
P23284 T113 Sugiyama PPIB CYPB FHRVIKDFMIQGGDFtRGDGtGGKsIyGERFPDENFKLKHy
P23396 T242 Sugiyama RPS3 OK/SW-cl.26 PIsEQKGGKPEPPAMPQPVPtA___________________
P23526 S183 Sugiyama AHCY SAHH NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI
P23528 T63 Sugiyama CFL1 CFL DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23528 T88 Sugiyama CFL1 CFL yAtFVKMLPDKDCRyALyDAtyEtKESKKEDLVFIFWAPES
P23921 T555 Sugiyama RRM1 RR1 IyyGALEASCDLAKEQGPyEtyEGsPVsKGILQYDMWNVTP
P24752 T220 Sugiyama ACAT1 ACAT MAT TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV
P25786 T11 Sugiyama PSMA1 HC2 NU PROS30 PSC2 __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ
P25788 S243 Sugiyama PSMA3 HC8 PSC8 GRHEIVPKDIREEAEKyAKEsLKEEDEsDDDNM________
P26038 S576 Sugiyama MSN YKtLRQIRQGNTKQRIDEFEsM___________________
P26038 T299 Sugiyama MSN RILALCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQME
P26038 T425 Sugiyama MSN QAsRDQKKTQEQLALEMAELtARIsQLEMARQKKEsEAVEW
P26373 S181 Sugiyama RPL13 BBC1 OK/SW-cl.46 YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE
P26373 T148 Sugiyama RPL13 BBC1 OK/SW-cl.46 PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV
P26373 T151 Sugiyama RPL13 BBC1 OK/SW-cl.46 PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE
P26641 S304 Sugiyama EEF1G EF1G PRO1608 PKstFVLDEFKRKysNEDtLsVALPyFWEHFDKDGWSLWyS
P26641 T302 Sugiyama EEF1G EF1G PRO1608 HLPKstFVLDEFKRKysNEDtLsVALPyFWEHFDKDGWSLW
P26641 T411 Sugiyama EEF1G EF1G PRO1608 QVDyESyTWRKLDPGsEEtQtLVREyFSWEGAFQHVGKAFN
P27797 S78 Sugiyama CALR CRTC GDEEKDKGLQTSQDARFyALsAsFEPFSNKGQTLVVQFTVK
P27797 S80 Sugiyama CALR CRTC EEKDKGLQTSQDARFyALsAsFEPFSNKGQTLVVQFTVKHE
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P28066 S159 Sugiyama PSMA5 VALLFGGVDEKGPQLFHMDPsGtFVQCDARAIGsAsEGAQs
P29401 S548 Sugiyama TKT NIRVLDPFTIKPLDRKLILDsARAtKGRILTVEDHYYEGGI
P29401 T444 Sugiyama TKT DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT
P29401 T454 Sugiyama TKT LAMFRsVPtstVFyPsDGVAtEKAVELAANTKGICFIRTsR
P29692 T129 Sugiyama EEF1D EF1D EARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPA
P30050 T135 Sugiyama RPL12 QMRHRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDI
P30050 T18 Sugiyama RPL12 ___MPPKFDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLs
P30050 T25 Sugiyama RPL12 FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD
P30086 S60 Sugiyama PEBP1 PBP PEBP VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK
P30086 T101 Sugiyama PEBP1 PBP PEBP YREWHHFLVVNMKGNDIssGtVLsDyVGsGPPKGtGLHRyV
P30101 T437 Sugiyama PDIA3 ERP57 ERP60 GRP58 KELGEKLsKDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsP
P30101 T485 Sugiyama PDIA3 ERP57 ERP60 GRP58 KKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKKKAQEDL
P30419 T122 Sugiyama NMT1 NMT GQGPAKTMEEASKRSyQFWDtQPVPKLGEVVNtHGPVEPDK
P31153 S247 Sugiyama MAT2A AMS2 MATA2 IKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLtGRKII
P31153 T240 Sugiyama MAT2A AMS2 MATA2 DALKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAG
P31327 S898 Sugiyama CPS1 LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS
P31327 T900 Sugiyama CPS1 KMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKC
P31327 T903 Sugiyama CPS1 DILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKCLGL
P31942 S298 Sugiyama HNRNPH3 HNRPH3 GGsGMGGYGRDGMDNQGGyGsVGRMGMGNNysGGyGtPDGL
P31943 S281 Sugiyama HNRNPH1 HNRPH HNRPH1 GRDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAt
P31943 S285 Sugiyama HNRNPH1 HNRPH HNRPH1 NyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDI
P31943 T287 Sugiyama HNRNPH1 HNRPH HNRPH1 CFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIyN
P31948 T145 Sugiyama STIP1 MNPFNMPNLYQKLESDPRtRtLLSDPTYRELIEQLRNKPSD
P31948 T243 Sugiyama STIP1 KQALKEKELGNDAYKKKDFDtALKHYDKAKELDPtNMtyIT
P31949 T33 Sugiyama S100A11 MLN70 S100C CIESLIAVFQKYAGKDGyNytLsKtEFLsFMNTELAAFTKN
P33992 T226 Sugiyama MCM5 CDC46 KCPLDPyFIMPDKCKCVDFQtLKLQELPDAVPHGEMPRHMQ
P34896 T94 Sugiyama SHMT1 SEGyPGQRYYGGTEFIDELEtLCQKRALQAYKLDPQCWGVN
P34897 T276 Sugiyama SHMT2 SGLVAAKVIPsPFKHADIVTtTTHKtLRGARSGLIFyRKGV
P34897 T281 Sugiyama SHMT2 AKVIPsPFKHADIVTtTTHKtLRGARSGLIFyRKGVKAVDP
P34931 T228 Sugiyama HSPA1L DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK
P34931 T39 Sugiyama HSPA1L CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P34931 T47 Sugiyama HSPA1L KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN
P34931 T49 Sugiyama HSPA1L EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQNTV
P35221 S641 Sugiyama CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35241 T299 Sugiyama RDX RILALCMGNHELYMRRRKPDtIEVQQMKAQAREEKHQKQLE
P35269 S399 Sugiyama GTF2F1 RAP74 GSSRGNsRPGtPsAEGGstsstLRAAASKLEQGKRVSEMPA
P35269 T41 Sugiyama GTF2F1 RAP74 NTTKKyNIMAFNAADKVNFAtWNQARLERDLSNKKIyQEEE
P35579 T1151 Sugiyama MYH9 EKQKRDLGEELEALKtELEDtLDstAAQQELRSKREQEVNI
P35579 T1208 Sugiyama MYH9 QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE
P35579 T1764 Sugiyama MYH9 NtELINDRLKKANLQIDQINtDLNLERSHAQKNENARQQLE
P35579 T1904 Sugiyama MYH9 EEAQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRG
P35579 T1906 Sugiyama MYH9 AQRANAsRRKLQRELEDAtEtADAMNREVssLKNKLRRGDL
P35606 S350 Sugiyama COPB2 MGDAEIKDGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVC
P36578 S63 Sugiyama RPL4 RPL1 NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG
P36578 S66 Sugiyama RPL4 RPL1 KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR
P36578 S87 Sugiyama RPL4 RPL1 WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT
P36578 T62 Sugiyama RPL4 RPL1 TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG
P36578 T69 Sugiyama RPL4 RPL1 RQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHRsGQ
P36578 T84 Sugiyama RPL4 RPL1 AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37108 T29 Sugiyama SRP14 FLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGtVEGF
P37108 T45 Sugiyama SRP14 sVyItLKKYDGRTKPIPKKGtVEGFEPADNKCLLRATDGKK
P37802 S145 Sugiyama TAGLN2 KIAA0120 CDABP0035 VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN
P37802 T113 Sugiyama TAGLN2 KIAA0120 CDABP0035 IsQFLQAAERYGINTTDIFQtVDLWEGKNMACVQRTLMNLG
P37802 T180 Sugiyama TAGLN2 KIAA0120 CDABP0035 RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P38117 T172 Sugiyama ETFB FP585 QVTLEGDKLKVEREIDGGLEtLRLKLPAVVTADLRLNEPRy
P38646 S473 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VFTKLINRNTTIPTKKSQVFstAADGQtQVEIKVCQGEREM
P38646 T116 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD
P38646 T120 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV
P38646 T398 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA
P38646 T474 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 FTKLINRNTTIPTKKSQVFstAADGQtQVEIKVCQGEREMA
P38646 T480 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 RNTTIPTKKSQVFstAADGQtQVEIKVCQGEREMAGDNKLL
P38646 T86 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 S59 Sugiyama RPS19 LAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIY
P39019 T60 Sugiyama RPS19 AKHKELAPyDENWFytRAAstARHLYLRGGAGVGsMTKIYG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P39748 T127 Sugiyama FEN1 RAD2 AEKQLQQAQAAGAEQEVEKFtKRLVKVTKQHNDECKHLLSL
P40429 T155 Sugiyama RPL13A FAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYRKKKQLM
P40763 T622 PSP STAT3 APRF PPGTFLLRFSESSKEGGVTFtWVEKDISGKTQIQSVEPyTK
P40925 T135 Sugiyama MDH1 MDHA ALDKYAKKSVKVIVVGNPANtNCLtAsKSAPSIPKENFsCL
P40925 T139 Sugiyama MDH1 MDHA YAKKSVKVIVVGNPANtNCLtAsKSAPSIPKENFsCLtRLD
P40925 T225 Sugiyama MDH1 MDHA KEVGVyEALKDDsWLKGEFVttVQQRGAAVIKARKLssAMS
P40926 T227 Sugiyama MDH2 PLISQCtPKVDFPQDQLtALtGRIQEAGtEVVKAKAGAGsA
P41091 T41 Sugiyama EIF2S3 EIF2G ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
P41091 T46 Sugiyama EIF2S3 EIF2G tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHt
P41208 T45 Sugiyama CETN2 CALT CEN2 LtEEQKQEIREAFDLFDADGtGtIDVKELKVAMRALGFEPK
P41208 T47 Sugiyama CETN2 CALT CEN2 EEQKQEIREAFDLFDADGtGtIDVKELKVAMRALGFEPKKE
P41252 T507 Sugiyama IARS1 IARS LEELSGAKISDLHRESVDHLtIPsRCGKGSLHRISEVFDCW
P42166 T137 Sugiyama TMPO LAP2 NEDLLDQLVKyGVNPGPIVGttRKLYEKKLLKLREQGtEsR
P42167 T137 Sugiyama TMPO LAP2 NEDLLDQLVKyGVNPGPIVGtTRKLYEKKLLKLREQGTESR
P42224 S640 Sugiyama STAT1 SQNGGEPDFHAVEPYTKKELsAVtFPDIIRNYKVMAAENIP
P42224 T643 Sugiyama STAT1 GGEPDFHAVEPYTKKELsAVtFPDIIRNYKVMAAENIPENP
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P42677 T74 Sugiyama RPS27 MPS1 VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
P43034 T247 Sugiyama PAFAH1B1 LIS1 MDCR MDS PAFAHA VKTFTGHREWVRMVRPNQDGtLIASCSNDQTVRVWVVATKE
P46060 S50 Sugiyama RANGAP1 KIAA1835 SD LKLNTAEDAKDVIKEIEDFDsLEALRLEGNtVGVEAARVIA
P46060 T60 Sugiyama RANGAP1 KIAA1835 SD DVIKEIEDFDsLEALRLEGNtVGVEAARVIAKALEKKSELK
P46776 S68 Sugiyama RPL27A yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV
P46776 T72 Sugiyama RPL27A yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK
P46776 Y52 Sugiyama RPL27A RGNAGGLHHHRINFDKyHPGyFGKVGMKHYHLKRNQsFCPt
P46779 T80 Sugiyama RPL28 VVVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKN
P46779 T81 Sugiyama RPL28 VVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKNK
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46783 T148 Sugiyama RPS10 RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___
P46937 S127 EPSD|PSP YAP1 YAP65 QAstDAGtAGALtPQHVRAHssPAsLQLGAVsPGtLtPtGV
P46940 T1471 Sugiyama IQGAP1 KIAA0051 tLQEKKEKIQTGLKKLTELGtVDPKNKyQELINDIARDIRN
P47756 T186 Sugiyama CAPZB HYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDC
P48643 S51 Sugiyama CCT5 CCTE KIAA0098 LEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtVT
P48643 T47 Sugiyama CCT5 CCTE KIAA0098 RLMGLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGD
P48643 T50 Sugiyama CCT5 CCTE KIAA0098 GLEALKSHIMAAKAVANtMRtsLGPNGLDKMMVDKDGDVtV
P48739 S165 Sugiyama PITPNB DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP
P48741 T228 Sugiyama HSPA7 HSP70B DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR
P48741 T47 Sugiyama HSPA7 HSP70B RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN
P48741 T49 Sugiyama HSPA7 HSP70B EILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHNtV
P49327 T1999 Sugiyama FASN FAS LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF
P49368 T373 Sugiyama CCT3 CCTG TRIC5 KKIGDEYFTFITDCKDPKACtILLRGAsKEILSEVERNLQD
P49368 T459 Sugiyama CCT3 CCTG TRIC5 AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG
P49368 T486 Sugiyama CCT3 CCTG TRIC5 LRAKHtQENCEtWGVNGEtGtLVDMKELGIWEPLAVKLQTY
P49773 T17 Sugiyama HINT1 HINT PKCI1 PRKCNH1 ____MADEIAKAQVARPGGDtIFGKIIRKEIPAKIIFEDDR
P49792 T2679 Sugiyama RANBP2 NUP358 CYKNRPDyVsEEEEDDEDFEtAVKKLNGKLYLDGsEKCRPL
P50395 T205 Sugiyama GDI2 RABGDIB TGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsPYL
P50395 T407 Sugiyama GDI2 RABGDIB LVPKDLGtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGs
P50395 T413 Sugiyama GDI2 RABGDIB GtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFEE
P50990 T374 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 EVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDD
P50991 T69 Sugiyama CCT4 CCTD SRB RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR
P50991 T71 Sugiyama CCT4 CCTD SRB sLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAARML
P50991 T76 Sugiyama CCT4 CCTD SRB GMDKMIQDGKGDVtItNDGAtILKQMQVLHPAARMLVELSK
P51149 T168 Sugiyama RAB7A RAB7 NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE
P51659 T191 Sugiyama HSD17B4 EDH17B4 SDR8C1 LLGLANSLAIEGRKsNIHCNtIAPNAGsRMTQTVMPEDLVE
P51858 T94 Sugiyama HDGF HMG1L2 GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP
P51955 S356 GPS6|EPSD|PSP NEK2 NEK2A NLK1 VRERLAEDKLARAENLLKNYsLLKERKFLsLAsNPELLNLP
P51955 S365 GPS6|EPSD|PSP NEK2 NEK2A NLK1 LARAENLLKNYsLLKERKFLsLAsNPELLNLPsSVIKKKVH
P51955 S406 GPS6|EPSD|PSP NEK2 NEK2A NLK1 FSGESKENIMRsENSEsQLTsKSKCKDLKKRLHAAQLRAQA
P51955 S438 GPS6|EPSD|PSP NEK2 NEK2A NLK1 HAAQLRAQALsDIEKNYQLKsRQILGMR_____________
P51991 S370 Sugiyama HNRNPA3 HNRPA3 sFGGRssGsPyGGGyGsGGGsGGyGsRRF____________
P51991 S375 Sugiyama HNRNPA3 HNRPA3 ssGsPyGGGyGsGGGsGGyGsRRF_________________
P52907 T249 Sugiyama CAPZA1 IKIIENAENEyQTAIsENyQtMSDTTFKALRRQLPVTRTKI
P52948 T172 Sugiyama NUP98 ADAR2 SFTAAPTGTTIKFNPPTGTDtMVKAGVSTNISTKHQCITAM
P53634 T431 Sugiyama CTSC CPPI GYGTDSASGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIE
P54105 T34 Sugiyama CLNS1A CLCI ICLN EGLLRQQPDTEAVLNGKGLGtGtLyIAEsRLSWLDGsGLGF
P54105 T36 Sugiyama CLNS1A CLCI ICLN LLRQQPDTEAVLNGKGLGtGtLyIAEsRLSWLDGsGLGFSL
P54652 T229 Sugiyama HSPA2 DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK
P54652 T38 Sugiyama HSPA2 CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN
P54652 T46 Sugiyama HSPA2 KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN
P54652 T48 Sugiyama HSPA2 EIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTNTI
P54819 T192 Sugiyama AK2 ADK2 LIRRsDDNEKALKIRLQAyHtQttPLIEyyRKRGIHSAIDA
P54819 T194 Sugiyama AK2 ADK2 RRsDDNEKALKIRLQAyHtQttPLIEyyRKRGIHSAIDASQ
P55060 S931 Sugiyama CSE1L CAS XPO2 KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL
P55060 T339 Sugiyama CSE1L CAS XPO2 QFLASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADE
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55209 T269 Sugiyama NAP1L1 NRP GPEIMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVT
P55209 T272 Sugiyama NAP1L1 NRP IMGCTGCQIDWKKGKNVtLKtIKKKQKHKGRGTVRTVTKTV
P55209 T64 Sugiyama NAP1L1 NRP QNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNL
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P57721 S173 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT KEIREstGAQVQVAGDMLPNstERAVTISGTPDAIIQCVKQ
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 S97 Sugiyama TPI1 TPI GEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELIGQKVAHA
P60174 T173 Sugiyama TPI1 TPI DNVKDWSKVVLAyEPVWAIGtGKtATPQQAQEVHEKLRGWL
P60174 T176 Sugiyama TPI1 TPI KDWSKVVLAyEPVWAIGtGKtATPQQAQEVHEKLRGWLKsN
P60174 T217 Sugiyama TPI1 TPI VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL
P60174 T28 Sugiyama TPI1 TPI FVGGNWKMNGRKQsLGELIGtLNAAKVPADtEVVCAPPtAy
P60174 T90 Sugiyama TPI1 TPI VTNGAFtGEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELI
P60660 T103 Sugiyama MYL6 QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE
P60660 T22 Sugiyama MYL6 CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S323 Sugiyama ACTB ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 T106 Sugiyama ACTB WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P60709 T201 Sugiyama ACTB AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P60709 T202 Sugiyama ACTB GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P60709 T249 Sugiyama ACTB tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P60709 T297 Sugiyama ACTB TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709 T304 Sugiyama ACTB KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P60709 T318 Sugiyama ACTB VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P60709 T324 Sugiyama ACTB tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60842 T80 Sugiyama EIF4A1 DDX2A EIF4A QRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDLKA
P60866 T9 Sugiyama RPS20 ____________MAFKDtGKtPVEPEVAIHRIRITLTSRNV
P61204 S147 Sugiyama ARF3 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 S237 Sugiyama RPS3A FTE1 MFTL MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE
P61254 S23 Sugiyama RPL26 FNPFVtsDRsKNRKRHFNAPsHIRRKIMssPLSKELRQKYN
P61289 T99 Sugiyama PSME3 LDGPTYKKRRLDECEEAFQGtKVFVMPNGMLKSNQQLVDII
P61313 S97 Sugiyama RPL15 EC45 TCBAP0781 KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN
P61313 Y59 Sugiyama RPL15 EC45 TCBAP0781 APRPTRPDKARRLGYKAKQGyVIyRIRVRRGGRKRPVPKGA
P61313 Y6 Sugiyama RPL15 EC45 TCBAP0781 _______________MGAYKyIQELWRKKQSDVMRFLLRVR
P61353 T94 Sugiyama RPL27 VyNyNHLMPtRysVDIPLDKtVVNKDVFRDPALKRKARREA
P61604 T45 Sugiyama HSPE1 TVTKGGIMLPEKSQGKVLQAtVVAVGsGsKGKGGEIQPVsV
P61604 T79 Sugiyama HSPE1 EIQPVsVKVGDKVLLPEyGGtKVVLDDKDyFLFRDGDILGK
P61758 T171 Sugiyama VBP1 PFDN3 ATKNLDsLEEDLDFLRDQFTtTEVNMARVyNWDVKRRNKDD
P61769 T106 Sugiyama B2M CDABP0092 HDCMA22P YYTEFTPTEKDEYACRVNHVtLsQPKIVKWDRDM_______
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P62081 S119 Sugiyama RPS7 RILPKPTRKSRTKNKQKRPRsRtLtAVHDAILEDLVFPsEI
P62081 S137 Sugiyama RPS7 PRsRtLtAVHDAILEDLVFPsEIVGKRIRVKLDGSRLIKVH
P62081 T121 Sugiyama RPS7 LPKPTRKSRTKNKQKRPRsRtLtAVHDAILEDLVFPsEIVG
P62081 T123 Sugiyama RPS7 KPTRKSRTKNKQKRPRsRtLtAVHDAILEDLVFPsEIVGKR
P62241 S160 Sugiyama RPS8 OK/SW-cl.83 KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 S148 Sugiyama YWHAE YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP
P62258 T114 Sugiyama YWHAE KLICCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAE
P62263 S139 Sugiyama RPS14 PRO2640 LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________
P62263 T140 Sugiyama RPS14 PRO2640 ARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL_________
P62266 S45 Sugiyama RPS23 KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA
P62266 T34 Sugiyama RPS23 RSHRRDQKWHDKQYKKAHLGtALKANPFGGAsHAKGIVLEK
P62273 Y34 Sugiyama RPS29 FGQGSRSCRVCSNRHGLIRKyGLNMCRQCFRQYAKDIGFIK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 T15 Sugiyama RPS11 ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR
P62280 T28 Sugiyama RPS11 RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK
P62280 T54 Sugiyama RPS11 PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs
P62424 T84 Sugiyama RPL7A SURF-3 SURF3 QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP
P62424 T93 Sugiyama RPL7A SURF-3 SURF3 RLKVPPAINQFtQALDRQTAtQLLKLAHKYRPEtKQEKKQR
P62495 T298 Sugiyama ETF1 ERF1 RF1 SUP45L1 VKFIQEKKLIGRyFDEIsQDtGKyCFGVEDTLKALEMGAVE
P62736 S325 Sugiyama ACTA2 ACTSA ACTVS GIG46 tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P62736 T251 Sugiyama ACTA2 ACTSA ACTVS GIG46 tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P62736 T320 Sugiyama ACTA2 ACTSA ACTVS GIG46 VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P62736 T326 Sugiyama ACTA2 ACTSA ACTVS GIG46 TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 T126 Sugiyama RPL23A KHQIKQAVKKLyDIDVAKVNtLIRPDGEKKAYVRLAPDyDA
P62826 S150 Sugiyama RAN ARA24 OK/SW-cl.81 KVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARKLIG
P62826 T21 Sugiyama RAN ARA24 OK/SW-cl.81 MAAQGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVA
P62826 T24 Sugiyama RAN ARA24 OK/SW-cl.81 QGEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVATLG
P62826 T25 Sugiyama RAN ARA24 OK/SW-cl.81 GEPQVQFKLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGV
P62826 T32 Sugiyama RAN ARA24 OK/SW-cl.81 KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF
P62857 T38 Sugiyama RPS28 LGRtGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtL
P62857 T57 Sugiyama RPS28 DtsRsIIRNVKGPVREGDVLtLLEsEREARRLR________
P62888 T83 Sugiyama RPL30 yAMLAKtGVHHysGNNIELGtACGKyyRVCtLAIIDPGDsD
P62899 T107 Sugiyama RPL31 RLSRKRNEDEDsPNKLytLVtyVPVttFKNLQtVNVDEN__
P62899 T119 Sugiyama RPL31 PNKLytLVtyVPVttFKNLQtVNVDEN______________
P62899 T22 Sugiyama RPL31 APAKKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRA
P62899 T26 Sugiyama RPL31 KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL
P62899 Y25 Sugiyama RPL31 KKGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRA
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62917 S14 Sugiyama RPL8 _______MGRVIRGQRKGAGsVFRAHVKHRKGAARLRAVDF
P62917 T135 Sugiyama RPL8 CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK
P62917 T143 Sugiyama RPL8 RGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVISSANR
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62942 T15 Sugiyama FKBP1A FKBP1 FKBP12 ______MGVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGK
P62942 T22 Sugiyama FKBP1A FKBP1 FKBP12 GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD
P62942 T28 Sugiyama FKBP1A FKBP1 FKBP12 IsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPFK
P62942 T7 Sugiyama FKBP1A FKBP1 FKBP12 ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy
P62942 Y27 Sugiyama FKBP1A FKBP1 FKBP12 tIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRDRNKPF
P63104 S28 Sugiyama YWHAZ QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy
P63167 T26 Sugiyama DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220 S68 Sugiyama RPS21 GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____
P63241 S100 Sugiyama EIF5A DVPNIKRNDFQLIGIQDGyLsLLQDSGEVREDLRLPEGDLG
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S323 Sugiyama ACTG1 ACTG ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 T106 Sugiyama ACTG1 ACTG WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET
P63261 T201 Sugiyama ACTG1 ACTG AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL
P63261 T202 Sugiyama ACTG1 ACTG GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD
P63261 T249 Sugiyama ACTG1 ACTG tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM
P63261 T297 Sugiyama ACTG1 ACTG TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261 T304 Sugiyama ACTG1 ACTG KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst
P63261 T318 Sugiyama ACTG1 ACTG VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs
P63261 T324 Sugiyama ACTG1 ACTG tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63267 S324 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P63267 T250 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P63267 T319 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P63267 T325 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67809 S102 Sugiyama YBX1 NSEP1 YB1 EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P67809 T108 Sugiyama YBX1 NSEP1 YB1 QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP
P67809 T126 Sugiyama YBX1 NSEP1 YB1 GEtVEFDVVEGEKGAEAANVtGPGGVPVQGsKYAADRNHYR
P67809 T89 Sugiyama YBX1 NSEP1 YB1 RNGyGFINRNDtKEDVFVHQtAIKKNNPRKyLRsVGDGEtV
P67809 Y72 Sugiyama YBX1 NSEP1 YB1 KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
P68032 S325 Sugiyama ACTC1 ACTC tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68032 T251 Sugiyama ACTC1 ACTC tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68032 T320 Sugiyama ACTC1 ACTC VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68032 T326 Sugiyama ACTC1 ACTC TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 T261 Sugiyama EEF1A1 EEF1A EF1A LENG7 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
P68104 T432 Sugiyama EEF1A1 EEF1A EF1A LENG7 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
P68133 S325 Sugiyama ACTA1 ACTA TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG
P68133 T251 Sugiyama ACTA1 ACTA tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM
P68133 T320 Sugiyama ACTA1 ACTA VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS
P68133 T326 Sugiyama ACTA1 ACTA TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 T334 Sugiyama TUBA1B ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG
P68363 T337 Sugiyama TUBA1B LLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVGINy
P68363 T51 Sugiyama TUBA1B QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
P68363 T56 Sugiyama TUBA1B MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
P68363 T80 Sugiyama TUBA1B KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
P68363 T82 Sugiyama TUBA1B VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
P68431 T46 Sugiyama H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P78371 T103 Sugiyama CCT2 99D8.1 CCTB VLVDMSRVQDDEVGDGTTsVtVLAAELLREAESLIAKKIHP
P78371 T242 Sugiyama CCT2 99D8.1 CCTB KKIGVNQPKRIENAKILIANtGMDtDKIKIFGsRVRVDstA
P78371 T246 Sugiyama CCT2 99D8.1 CCTB VNQPKRIENAKILIANtGMDtDKIKIFGsRVRVDstAKVAE
P78417 S23 Sugiyama GSTO1 GSTTLP28 GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK
P83731 T52 Sugiyama RPL24 LNAKCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRT
P83731 Y55 Sugiyama RPL24 KCEsAFLSKRNPRQINWtVLyRRKHKKGQsEEIQKKRTRRA
P84077 S147 Sugiyama ARF1 KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY
P84098 S12 Sugiyama RPL19 _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI
P84098 S122 Sugiyama RPL19 LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI
P84098 S13 Sugiyama RPL19 ________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEIA
P84098 S37 Sugiyama RPL19 CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV
P84098 T29 Sugiyama RPL19 RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL
P84098 Y124 Sugiyama RPL19 RLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHIHK
P84243 T46 Sugiyama H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
P99999 T50 Sugiyama CYCS CYC GPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEYLE
Q00839 T530 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 KTTWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtG
Q00839 T532 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 TWVTKHAAENPGKyNILGtNtIMDKMMVAGFKKQMADtGKL
Q00839 T549 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GtNtIMDKMMVAGFKKQMADtGKLNtLLQRAPQCLGKFIEI
Q00839 T554 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 MDKMMVAGFKKQMADtGKLNtLLQRAPQCLGKFIEIAARKK
Q00839 T582 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 CLGKFIEIAARKKRNFILDQtNVsAAAQRRKMCLFAGFQRK
Q01105 S168 Sugiyama SET ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN
Q01518 T165 Sugiyama CAP1 CAP AMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVKA
Q01650 T45 Sugiyama SLC7A5 CD98LC LAT1 MPE16 KMLAAKsADGsAPAGEGEGVtLQRNITLLNGVAIIVGTIIG
Q02543 T101 Sugiyama RPL18A WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA
Q02543 T107 Sugiyama RPL18A RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM
Q02878 T118 Sugiyama RPL6 TXREB1 GDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQHVR
Q02878 T213 Sugiyama RPL6 TXREB1 FVIAtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIF
Q02878 T235 Sugiyama RPL6 TXREB1 AyFKKKKLRKPRHQEGEIFDtEKEKYEITEQRKIDQKAVDs
Q02878 T91 Sugiyama RPL6 TXREB1 RKYSAAKSKVEKKKKEKVLAtVtKPVGGDKNGGTRVVKLRK
Q02878 Y216 Sugiyama RPL6 TXREB1 AtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIFDtE
Q04760 T35 Sugiyama GLO1 AALSCCSDADPSTKDFLLQQtMLRVKDPKKSLDFyTRVLGM
Q05639 T261 Sugiyama EEF1A2 EEF1AL STN PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA
Q05639 T432 Sugiyama EEF1A2 EEF1AL STN VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT
Q06830 T18 Sugiyama PRDX1 PAGA PAGB TDPX2 ___MSSGNAKIGHPAPNFKAtAVMPDGQFKDIsLsDyKGKY
Q07020 T136 Sugiyama RPL18 AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP
Q07020 T85 Sugiyama RPL18 RMIRKMKLPGRENKtAVVVGtItDDVRVQEVPKLKVCALRV
Q12792 T348 Sugiyama TWF1 PTK9 GPAGKRGIRRLIRGPAEtEAttD__________________
Q12874 S295 Sugiyama SF3A3 SAP61 GGTLEERAQRLFSTKGKsLEsLDtsLFAKNPKSKGTKRDTE
Q12874 T298 Sugiyama SF3A3 SAP61 LEERAQRLFSTKGKsLEsLDtsLFAKNPKSKGTKRDTERNK
Q12906 T300 Sugiyama ILF3 DRBF MPHOSPH4 NF90 ASGIVMPDGSGIYDPCEKEAtDAIGHLDRQQREDItQsAQH
Q13043 S65 Sugiyama STK4 KRS2 MST1 YKAIHKETGQIVAIKQVPVEsDLQEIIKEIsIMQQCDsPHV
Q13043 T175 Sugiyama STK4 KRS2 MST1 ILLNtEGHAKLADFGVAGQLtDtMAKRNtVIGtPFWMAPEV
Q13043 T177 Sugiyama STK4 KRS2 MST1 LNtEGHAKLADFGVAGQLtDtMAKRNtVIGtPFWMAPEVIQ
Q13131 T183 PSP PRKAA1 AMPK1 NAKIADFGLsNMMsDGEFLRtsCGsPNyAAPEVISGRLYAG
Q13136 S787 Sugiyama PPFIA1 LIP1 IRDIRNstGsQDGPVSNPsssNssQDsLHKAPKKKGIKSSI
Q13188 S15 Sugiyama STK3 KRS1 MST2 ______MEQPPAPKSKLKKLsEDsLtKQPEEVFDVLEKLGE
Q13188 S18 Sugiyama STK3 KRS1 MST2 ___MEQPPAPKSKLKKLsEDsLtKQPEEVFDVLEKLGEGsY
Q13188 S37 Sugiyama STK3 KRS1 MST2 DsLtKQPEEVFDVLEKLGEGsYGsVFKAIHKESGQVVAIKQ
Q13188 S385 Sugiyama STK3 KRS1 MST2 MVINSEDEEEEDGtMKRNAtsPQVQRPsFMDyFDKQDFKNK
Q13188 S392 Sugiyama STK3 KRS1 MST2 EEEEDGtMKRNAtsPQVQRPsFMDyFDKQDFKNKsHENCNQ
Q13188 S40 Sugiyama STK3 KRS1 MST2 tKQPEEVFDVLEKLGEGsYGsVFKAIHKESGQVVAIKQVPV
Q13188 S444 Sugiyama STK3 KRS1 MST2 VFPDNWKVPQDGDFDFLKNLsLEELQMRLKALDPMMEREIE
Q13188 S62 Sugiyama STK3 KRS1 MST2 FKAIHKESGQVVAIKQVPVEsDLQEIIKEISIMQQCDSPyV
Q13188 T172 Sugiyama STK3 KRS1 MST2 ILLNtEGHAKLADFGVAGQLtDtMAKRNtVIGTPFWMAPEV
Q13188 T174 Sugiyama STK3 KRS1 MST2 LNtEGHAKLADFGVAGQLtDtMAKRNtVIGTPFWMAPEVIQ
Q13188 T180 EPSD|PSP STK3 KRS1 MST2 AKLADFGVAGQLtDtMAKRNtVIGTPFWMAPEVIQEIGYNC
Q13188 T20 Sugiyama STK3 KRS1 MST2 _MEQPPAPKSKLKKLsEDsLtKQPEEVFDVLEKLGEGsYGs
Q13188 T378 EPSD|PSP STK3 KRS1 MST2 LESDLGTMVINSEDEEEEDGtMKRNAtsPQVQRPsFMDyFD
Q13188 T384 Sugiyama STK3 KRS1 MST2 TMVINSEDEEEEDGtMKRNAtsPQVQRPsFMDyFDKQDFKN
Q13188 Y396 Sugiyama STK3 KRS1 MST2 DGtMKRNAtsPQVQRPsFMDyFDKQDFKNKsHENCNQNMHE
Q13283 T241 Sugiyama G3BP1 G3BP ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP
Q13310 T191 Sugiyama PABPC4 APP1 PABP4 GRFKSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELF
Q13347 T201 Sugiyama EIF3I EIF3S2 TRIP1 LVNVKEHSRQINDIQLsRDMtMFVtASKDNTAKLFDsttLE
Q13347 T205 Sugiyama EIF3I EIF3S2 TRIP1 KEHSRQINDIQLsRDMtMFVtASKDNTAKLFDsttLEHQKT
Q13435 T315 Sugiyama SF3B2 SAP145 EMETDARssLGQsAsEtEEDtVsVsKKEKNRKRRNRKKKKK
Q13442 T92 Sugiyama PDAP1 HASPP28 QKRKGVEGLIDIENPNRVAQttKKVtQLDLDGPKELSRRER
Q13442 T93 Sugiyama PDAP1 HASPP28 KRKGVEGLIDIENPNRVAQttKKVtQLDLDGPKELSRRERE
Q13561 S83 Sugiyama DCTN2 DCTN50 GTKGLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKY
Q13561 T315 Sugiyama DCTN2 DCTN50 KHKASVEDADTQSKVHQLyEtIQRWsPIASTLPELVQRLVT
Q13765 T214 Sugiyama NACA HSD48 KAVRALKNNSNDIVNAIMELtM___________________
Q14103 T127 Sugiyama HNRNPD AUF1 HNRPD DTTKKDLKDYFSKFGEVVDCtLKLDPITGRSRGFGFVLFKE
Q14103 T91 Sugiyama HNRNPD AUF1 HNRPD sKNEEDEGHsNssPRHsEAAtAQREEWKMFIGGLSWDTTKK
Q14152 S1262 Sugiyama EIF3A EIF3S10 KIAA0139 PRDEGGWRRGPAEEsssWRDssRRDDRDRDDRRRERDDRRD
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14152 T1379 Sugiyama EIF3A EIF3S10 KIAA0139 EKDREsLRRTKNEtDEDGWttVRR_________________
Q14157 T23 Sugiyama UBAP2L KIAA0144 NICE4 TSVGTNRARGNWEQPQNQNQtQHKQRPQATAEQIRLAQMIS
Q14192 T234 Sugiyama FHL2 DRAL SLIM3 CDLyAKKCAGCTNPISGLGGtKyIsFEERQWHNDCFNCKKC
Q14240 T81 Sugiyama EIF4A2 DDX2B EIF4F QRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEFKE
Q14247 T219 Sugiyama CTTN EMS1 yGIDKDKVDKsAVGFEyQGKtEKHESQKDyVKGFGGKFGVQ
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14568 T109 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 LTIVDTGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS
Q14568 T171 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 ITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILHLK
Q14677 T271 Sugiyama CLINT1 ENTH EPN4 EPNR KIAA0171 KDEEETVTTKHIHItQATEttttRHKRTANPsKtIDLGAAA
Q14683 T1005 Sugiyama SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 DLCEDLKDAQAEEEIKQEMNtLQQKLNEQQsVLQRIAAPNM
Q14697 T40 Sugiyama GANAB G2AN KIAA0088 LAFLGVCLGITLAVDRSNFKtCEEssFCKRQRsIRPGLsPy
Q15056 S110 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK
Q15056 S94 Sugiyama EIF4H KIAA0038 WBSCR1 WSCR1 RDKDTDKFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVD
Q15084 T239 Sugiyama PDIA6 ERP5 P5 TXNDC7 AVDAtVNQVLAsRYGIRGFPtIKIFQKGEsPVDyDGGRTRs
Q15181 T245 Sugiyama PPA1 IOPPP PP DHWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDA
Q15181 T246 Sugiyama PPA1 IOPPP PP HWKALVTKKTNGKGIsCMNttLsEsPFKCDPDAARAIVDAL
Q15185 S72 Sugiyama PTGES3 P23 TEBP EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE
Q15293 T100 Sugiyama RCN1 RCN sKERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNV
Q15293 T71 Sugiyama RCN1 RCN EDNQsFQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRI
Q15365 S141 Sugiyama PCBP1 KEIREstGAQVQVAGDMLPNstERAITIAGVPQSVTECVKQ
Q15366 S141 Sugiyama PCBP2 KEIREstGAQVQVAGDMLPNstERAITIAGIPQSIIECVKQ
Q15369 T41 Sugiyama ELOC TCEB1 LISSDGHEFIVKREHALtsGtIKAMLSGPGQFAENETNEVN
Q15459 S506 Sugiyama SF3A1 SAP114 KKIGEEEIQKPEEKVTWDGHsGsMARTQQAAQANITLQEQI
Q15637 T26 Sugiyama SF1 ZFM1 ZNF162 NAtPLDFPsKKRKRsRWNQDtMEQKTVIPGMPTVIPPGLTR
Q15648 S1493 Sugiyama MED1 ARC205 CRSP1 CRSP200 DRIP205 DRIP230 PBP PPARBP PPARGBP RB18A TRAP220 TRIP2 EKsyQNsPssDDGIRPLPEYstEKHKKHKKEKKKVKDKDRD
Q16181 T426 Sugiyama SEPTIN7 CDC10 SEPT7 DEKANWEAQQRILEQQNssRtLEKNKKKGKIF_________
Q16576 T10 Sugiyama RBBP7 RBAP46 ___________MAsKEMFEDtVEERVINEEYKIWKKNTPFL
Q16637 T37 Sugiyama SMN1 SMN SMNT; SMN2 SMNC DsVLFRRGtGQsDDsDIWDDtALIKAYDKAVAsFKHALKNG
Q16658 T239 Sugiyama FSCN1 FAN1 HSN SNL GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs
Q16695 T46 Sugiyama H3-4 H3FT HIST3H3 ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q16775 T292 Sugiyama HAGH GLO2 HAGH1 FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____
Q2VIR3 T41 Sugiyama EIF2S3B ttLDVtKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAI
Q2VIR3 T46 Sugiyama EIF2S3B tKLTPLSHEVISRQAtINIGtIGHVAHGKSTVVKAISGVHT
Q3ZCM7 S75 Sugiyama TUBB8 SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC
Q3ZCM7 T72 Sugiyama TUBB8 NEASGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIF
Q562R1 T250 Sugiyama ACTBL2 RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF6 T165 Sugiyama HSP90AB4P DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S58 Sugiyama HSP90AB3P HSP90BC IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF7 S67 Sugiyama HSP90AB3P HSP90BC ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERTLALV
Q58FF7 T169 Sugiyama HSP90AB3P HSP90BC DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG
Q58FF7 T489 Sugiyama HSP90AB3P HSP90BC YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME
Q58FF7 Y492 Sugiyama HSP90AB3P HSP90BC TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR
Q58FF8 S58 Sugiyama HSP90AB2P HSP90BB IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 S67 Sugiyama HSP90AB2P HSP90BB ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQEHTLTLV
Q58FF8 T104 Sugiyama HSP90AB2P HSP90BB LTLVDTGIGMTKADLINNLGtIAKFQDQTEYLEEMQVKEVV
Q58FG0 Y178 Sugiyama HSP90AA5P HSP90AE QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK
Q58FG1 T248 Sugiyama HSP90AA4P HSP90AD HSPCAL2 YTIEPIDEYCVQQLKEFEGKtLVsVTKEDLELPEDEEEKKK
Q5T3I0 T271 Sugiyama GPATCH4 GPATC4 KVsDEREGTTKGNEKEDAAGtsGLGELNSREQtNQSLRKGK
Q5VTE0 T261 Sugiyama EEF1A1P5 EEF1AL3 PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA
Q5VTE0 T432 Sugiyama EEF1A1P5 EEF1AL3 VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT
Q6NXT2 T45 Sugiyama H3-5 H3F3C AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL
Q6PEY2 T334 Sugiyama TUBA3E ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q6PEY2 T337 Sugiyama TUBA3E MLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
Q6PEY2 T51 Sugiyama TUBA3E QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q6PEY2 T56 Sugiyama TUBA3E MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 T949 Sugiyama POTEE A26C1A POTE2 tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UXH1 T300 Sugiyama CRELD2 UNQ185/PRO211 GYAREHGQCADVDECsLAEKtCVRKNENCYNTPGSYVCVCP
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q6ZMR3 S167 Sugiyama LDHAL6A LDHL2 AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG
Q71DI3 T46 Sugiyama H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL
Q71U36 T334 Sugiyama TUBA1A TUBA3 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q71U36 T337 Sugiyama TUBA1A TUBA3 LLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
Q71U36 T51 Sugiyama TUBA1A TUBA3 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q71U36 T56 Sugiyama TUBA1A TUBA3 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q71U36 T80 Sugiyama TUBA1A TUBA3 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q71U36 T82 Sugiyama TUBA1A TUBA3 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q71UM5 T74 Sugiyama RPS27L VLCVGCSTVLCQPTGGKARLtEGCsFRRKQH__________
Q7L9L4 T12 EPSD|PSP MOB1B MOB4A MOBKL1A _________MsFLFGsRssKtFKPKKNIPEGSHQyELLKHA
Q7L9L4 T35 EPSD|PSP MOB1B MOB4A MOBKL1A PKKNIPEGSHQyELLKHAEAtLGsGNLRMAVMLPEGEDLNE
Q7L9L4 T74 EPSD|PSP MOB1B MOB4A MOBKL1A NEWVAVNTVDFFNQINMLYGtITDFCTEESCPVMSAGPKYE
Q7Z2W4 T294 Sugiyama ZC3HAV1 ZC3HDC2 PRO1677 PsPDQIsHRAsLEDAPVDDLtRKFtyLGsQDRARPPsGsSK
Q7Z739 T177 Sugiyama YTHDF3 YPPSSLGRAITDGQAGFGNDtLSKVPGISsIEQGMTGLKIG
Q86UE4 T477 Sugiyama MTDH AEG1 LYRIC stAQDtEELEKEIREDLPVNtsKTRPKQEKAFSLKtIstsD
Q86V81 T148 Sugiyama ALYREF ALY BEF THOC4 EFGtLKKAAVHYDRsGRsLGtADVHFERKADALKAMKQYNG
Q8IYD1 T444 Sugiyama GSPT2 ERF3B NRSIDGPIRLPIVDKYKDMGtVVLGKLESGSIFKGQQLVMM
Q8NBS9 T122 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 LGDKYNSMEDAKVYVAKVDCtAHsDVCsAQGVRGYPTLKLF
Q8NBS9 T264 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 KVDCtQHyELCsGNQVRGyPtLLWFRDGKKVDQYKGKRDLE
Q8NBS9 Y262 Sugiyama TXNDC5 TLP46 UNQ364/PRO700 IGKVDCtQHyELCsGNQVRGyPtLLWFRDGKKVDQYKGKRD
Q8TAM6 S280 Sugiyama ERMN KIAA1189 TISYRKIRKGNTKQRIDEFEsMMHL________________
Q8WXX5 S215 Sugiyama DNAJC9 EEAKEAEMSRKELGLDEGVDsLKAAIQSRQKDRQKEMDNFL
Q92522 T55 Sugiyama H1-10 H1FX KRKNSKKKNQPGKySQLVVEtIRRLGERNGSSLAKIYTEAK
Q92598 T63 Sugiyama HSPH1 HSP105 HSP110 KIAA0201 SKNRTIGVAAKNQQITHANNtVsNFKRFHGRAFNDPFIQKE
Q92882 T200 Sugiyama OSTF1 ATNAACAsLLKKKQGTDAVRtLsNAEDyLDDEDsD______
Q96AY3 T200 Sugiyama FKBP10 FKBP65 PSEC0056 HYNGTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLG
Q96AY3 T203 Sugiyama FKBP10 FKBP65 PSEC0056 GTLLDGTSFDTSYSKGGtyDtyVGsGWLIKGMDQGLLGMCP
Q96GQ7 S98 Sugiyama DDX27 cPERP-F RHLP HSPC259 PP3241 RsADFNPDFVFTEKEGTyDGsWALADVMSQLKKKRAATTLD
Q96GQ7 Y95 Sugiyama DDX27 cPERP-F RHLP HSPC259 PP3241 GKNRsADFNPDFVFTEKEGTyDGsWALADVMSQLKKKRAAT
Q96HC4 T80 Sugiyama PDLIM5 ENH L9 GMTHLEAQNKIKGCTGsLNMtLQRAsAAPKPEPVPVQKGEP
Q96QK1 T773 Sugiyama VPS35 MEM3 TCCCTA00141 DLPNLEssEEtEQINKHFHNtLEHLRLRREsPEsEGPIyEG
Q99460 T830 Sugiyama PSMD1 TFAYPAPLEVPKEKEKEKVStAVLsItAKAKKKEKEKEKKE
Q99460 T836 Sugiyama PSMD1 PLEVPKEKEKEKVStAVLsItAKAKKKEKEKEKKEEEKMEV
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99613 T880 Sugiyama EIF3C EIF3S8 AEKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMR
Q99729 S242 Sugiyama HNRNPAB ABBP1 HNRPAB SKCEIKVAQPKEVyQQQQyGsGGRGNRNRGNRGSGGGGGGG
Q99733 S54 Sugiyama NAP1L4 NAP2 NPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQ
Q99733 T58 Sugiyama NAP1L4 NAP2 LAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQVRCA
Q99733 Y55 Sugiyama NAP1L4 NAP2 PRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQV
Q99832 T57 Sugiyama CCT7 CCTH NIP7-1 RTTLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAK
Q99832 T64 Sugiyama CCT7 CCTH NIP7-1 GMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTLVDIAK
Q9BQ39 T148 Sugiyama DDX50 ETLTREQKEGAFsNFPIsEEtIKLLKGRGVTYLFPIQVKTF
Q9BQE3 T334 Sugiyama TUBA1C TUBA6 ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG
Q9BQE3 T337 Sugiyama TUBA1C TUBA6 LLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy
Q9BQE3 T51 Sugiyama TUBA1C TUBA6 QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE
Q9BQE3 T56 Sugiyama TUBA1C TUBA6 MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID
Q9BQE3 T80 Sugiyama TUBA1C TUBA6 KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA
Q9BQE3 T82 Sugiyama TUBA1C TUBA6 VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN
Q9BS26 T155 Sugiyama ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 yIRQQKSDPIQEIRDLAEIttLDRSKRNIIGYFEQKDSDNy
Q9BV86 T62 Sugiyama NTMT1 C9orf32 METTL11A NRMT NRMT1 AD-003 INSSRKFLQRFLREGPNKTGtsCALDCGAGIGRITKRLLLP
Q9BXP5 T702 Sugiyama SRRT ARS2 ASR2 EEEAQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKF
Q9BXP5 T705 Sugiyama SRRT ARS2 ASR2 AQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKFKGP
Q9BY43 T82 Sugiyama CHMP4A C14orf123 SHAX2 CDA04 HSPC134 ALQALRRKKRFEQQLAQTDGtLStLEFQREAIENATtNAEV
Q9BY43 T85 Sugiyama CHMP4A C14orf123 SHAX2 CDA04 HSPC134 ALRRKKRFEQQLAQTDGtLStLEFQREAIENATtNAEVLRT
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 T249 Sugiyama POTEKP ACTBL3 FKSG30 MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9GZQ8 T50 PSP MAP1LC3B MAP1ALC3 KIPVIIERYKGEKQLPVLDKtKFLVPDHVNMSELIKIIRRR
Q9GZT8 T149 Sugiyama NIF3L1 ALS2CR1 MDS015 My018 AYDAAPQGVNNWLAKGLGACtSRPIHPSKAPNyPTEGNHRV
Q9H0C5 S273 Sugiyama BTBD1 C15orf1 NS5ATP8 QRQQLPVTFGNKQKVLGKALsLIRFPLMTIEEFAAGPAQSG
Q9H173 T125 Sugiyama SIL1 UNQ545/PRO836 QYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEME
Q9H173 T127 Sugiyama SIL1 UNQ545/PRO836 EDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEMESs
Q9H2U1 T179 Sugiyama DHX36 DDX36 KIAA1488 MLEL1 RHAU NRsyIDRDsEyLLQENEPDGtLDQKLLEDLQKKKNDLRYIE
Q9H3K6 T27 Sugiyama BOLA2 BOLA2A My016; BOLA2B YLREKLQRDLEAEHVEVEDttLNRCsCsFRVLVVSAKFEGK
Q9H444 T85 Sugiyama CHMP4B C20orf178 SHAX1 ALQALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEV
Q9H444 T88 Sugiyama CHMP4B C20orf178 SHAX1 ALKRKKRYEKQLAQIDGtLstIEFQREALENANtNtEVLKN
Q9H4B6 S269 EPSD|PSP SAV1 WW45 GTYYVDHTNKKAQYRHPCAPsVPRyDQPPPVTYQPQQTERN
Q9H4B6 S27 EPSD|PSP SAV1 WW45 TKNEVSKPAEVQGKYVKKEtsPLLRNLMPsFIRHGPTIPRR
Q9H4B6 S36 EPSD|PSP SAV1 WW45 EVQGKYVKKEtsPLLRNLMPsFIRHGPTIPRRTDICLPDSs
Q9H4B6 T26 EPSD|PSP SAV1 WW45 KTKNEVSKPAEVQGKYVKKEtsPLLRNLMPsFIRHGPTIPR
Q9H8S9 T12 EPSD|PSP MOB1A C2orf6 MOB4B MOBK1B MOBKL1B _________MsFLFssRssKtFKPKKNIPEGSHQyELLKHA
Q9H8S9 T35 EPSD|PSP MOB1A C2orf6 MOB4B MOBK1B MOBKL1B PKKNIPEGSHQyELLKHAEAtLGsGNLRQAVMLPEGEDLNE
Q9H8S9 T74 GPS6|EPSD|PSP MOB1A C2orf6 MOB4B MOBK1B MOBKL1B NEWIAVNTVDFFNQINMLYGtITEFCTEASCPVMSAGPRYE
Q9HB71 T209 Sugiyama CACYBP S100A6BP SIP PNAS-107 EGLMNVLKKIyEDGDDDMKRtINKAWVESREKQAKGDTEF_
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NQ39 T159 Sugiyama RPS10P5 RPS10L RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___
Q9NR30 T197 Sugiyama DDX21 QEIPVEQKEGAFsNFPIsEEtIKLLKGRGVTFLFPIQAKTF
Q9NZZ3 T23 Sugiyama CHMP5 C9orf83 SNF7DC2 CGI-34 HSPC177 PNAS-114 PNAS-2 RLFGKAKPKAPPPsLtDCIGtVDsRAEsIDKKISRLDAELV
Q9P258 T20 Sugiyama RCC2 KIAA1470 TD60 _MPRKKAAAAAWEEPssGNGtARAGPRKRGGPAGRKRERPE
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UII2 S39 Sugiyama ATP5IF1 ATPI ATPIF1 TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF
Q9ULW6 T342 Sugiyama NAP1L2 BPX GTAIEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVT
Q9ULW6 T345 Sugiyama NAP1L2 BPX IEYSTGCEIDWNEGKNVtLKtIKKKQKHRIWGTIRTVTEDF
Q9UQ80 T200 Sugiyama PA2G4 EBP1 TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV
Q9UQ80 T386 Sugiyama PA2G4 EBP1 tQKKKKKKAsKtAENAtsGEtLEENEAGD____________
Q9UQ80 T60 Sugiyama PA2G4 EBP1 ssGVsVLsLCEKGDAMIMEEtGKIFKKEKEMKKGIAFPTSI
Q9Y281 T88 Sugiyama CFL2 YtsFVKLLPLNDCRyALyDAtyEtKESKKEDLVFIFWAPES
Q9Y295 T62 Sugiyama DRG1 NEDD3 LITPKGGGGGGPGEGFDVAKtGDARIGFVGFPSVGKSTLLS
Q9Y2B0 S63 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2B0 T100 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL
Q9Y2B0 T132 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF
Q9Y2K2 T221 PSP SIK3 KIAA0999 QSK L19 NIKIADFGFSNLFTPGQLLKtWCGSPPYAAPELFEGKEYDG
Q9Y2T7 T124 Sugiyama YBX2 CSDA3 MSY2 RNGyGFINRNDtKEDVFVHQtAIKRNNPRKFLRsVGDGEtV
Q9Y2T7 Y107 Sugiyama YBX2 CSDA3 MSY2 KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
Q9Y2W1 T227 Sugiyama THRAP3 BCLAF2 TRAP150 sGGtsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRER
Q9Y2W1 T230 Sugiyama THRAP3 BCLAF2 TRAP150 tsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERsPA
Q9Y2W1 Y228 Sugiyama THRAP3 BCLAF2 TRAP150 GGtsQDTKAsEssKPWPDAtyGtGsAsRAsAVsELsPRERs
Q9Y2X3 S434 Sugiyama NOP58 NOL5 NOP5 HSPC120 AKTEKYEHKSEVKtyDPSGDstLPtCsKKRKIEQVDKEDEI
Q9Y2X3 T435 Sugiyama NOP58 NOL5 NOP5 HSPC120 KTEKYEHKSEVKtyDPSGDstLPtCsKKRKIEQVDKEDEIT
Q9Y2X3 Y428 Sugiyama NOP58 NOL5 NOP5 HSPC120 GTGKALAKTEKYEHKSEVKtyDPSGDstLPtCsKKRKIEQV
Q9Y3F4 S230 Sugiyama STRAP MAWD UNRIP SAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLyKy
Q9Y3F4 T225 Sugiyama STRAP MAWD UNRIP SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF
Q9Y3F4 T48 Sugiyama STRAP MAWD UNRIP YGYFLISACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLN
Q9Y3F4 T54 Sugiyama STRAP MAWD UNRIP SACKDGKPMLRQGDtGDWIGtFLGHKGAVWGAtLNKDATKA
Q9Y4L1 S742 Sugiyama HYOU1 GRP170 HSPH4 ORP150 KLQDLTLRDLEKQEREKAANsLEAFIFEtQDKLyQPEyQEV
Q9Y4L1 T750 Sugiyama HYOU1 GRP170 HSPH4 ORP150 DLEKQEREKAANsLEAFIFEtQDKLyQPEyQEVsTEEQREE
Q9Y5L4 S57 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW
Q9Y5L4 T79 Sugiyama TIMM13 TIM13B TIMM13A TIMM13B DNSEQKCIAMCMDRyMDAWNtVsRAYNSRLQRERANM____
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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name reactome_id p -log10p ref_path ref_path_lowest
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 5.956086e-07 6.225 0 0
Apoptotic execution phase R-HSA-75153 5.764448e-07 6.239 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.337549e-07 6.134 0 0
Mitotic Prometaphase R-HSA-68877 1.157480e-05 4.936 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.287044e-05 4.890 0 0
Signaling by ALK in cancer R-HSA-9700206 1.287044e-05 4.890 0 0
Cell Cycle, Mitotic R-HSA-69278 1.182340e-04 3.927 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 1.784065e-04 3.749 0 0
Amplification of signal from the kinetochores R-HSA-141424 1.784065e-04 3.749 0 0
Cell Cycle R-HSA-1640170 1.832547e-04 3.737 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 1.941571e-04 3.712 0 0
Signaling by Hippo R-HSA-2028269 3.385681e-04 3.470 1 1
Interaction between L1 and Ankyrins R-HSA-445095 4.942911e-04 3.306 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 5.679185e-04 3.246 0 0
Nephrin family interactions R-HSA-373753 6.580226e-04 3.182 0 0
Axon guidance R-HSA-422475 7.402902e-04 3.131 0 0
Mitotic Spindle Checkpoint R-HSA-69618 8.322151e-04 3.080 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 8.189506e-04 3.087 0 0
M Phase R-HSA-68886 7.748723e-04 3.111 0 0
Membrane Trafficking R-HSA-199991 9.603734e-04 3.018 0 0
Nuclear Receptor transcription pathway R-HSA-383280 1.024161e-03 2.990 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.097875e-03 2.959 0 0
Type I hemidesmosome assembly R-HSA-446107 1.188516e-03 2.925 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.188516e-03 2.925 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.233515e-03 2.909 0 0
Cell Cycle Checkpoints R-HSA-69620 1.438279e-03 2.842 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.657255e-03 2.781 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.774897e-03 2.751 0 0
Kinesins R-HSA-983189 2.276114e-03 2.643 0 0
Signaling by VEGF R-HSA-194138 2.310189e-03 2.636 0 0
Nervous system development R-HSA-9675108 2.300391e-03 2.638 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.479156e-03 2.606 0 0
Signal Transduction R-HSA-162582 2.637837e-03 2.579 1 0
Programmed Cell Death R-HSA-5357801 2.879937e-03 2.541 0 0
Semaphorin interactions R-HSA-373755 3.019300e-03 2.520 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.527318e-03 2.453 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 4.037986e-03 2.394 0 0
EPH-Ephrin signaling R-HSA-2682334 3.765503e-03 2.424 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 4.037986e-03 2.394 0 0
Apoptosis R-HSA-109581 3.693793e-03 2.433 0 0
Interleukin-37 signaling R-HSA-9008059 4.037986e-03 2.394 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 4.534847e-03 2.343 0 0
Integrin signaling R-HSA-354192 5.898706e-03 2.229 0 0
G2/M DNA replication checkpoint R-HSA-69478 6.312501e-03 2.200 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 6.527375e-03 2.185 0 0
Regulation of KIT signaling R-HSA-1433559 6.816731e-03 2.166 0 0
Signal regulatory protein family interactions R-HSA-391160 6.816731e-03 2.166 0 0
SOS-mediated signalling R-HSA-112412 8.403571e-03 2.076 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 8.403571e-03 2.076 0 0
Signaling by ERBB2 R-HSA-1227986 7.714003e-03 2.113 0 0
L1CAM interactions R-HSA-373760 8.374382e-03 2.077 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 9.999797e-03 2.000 0 0
Separation of Sister Chromatids R-HSA-2467813 9.290225e-03 2.032 0 0
Signaling by PTK6 R-HSA-8848021 9.819559e-03 2.008 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 9.819559e-03 2.008 0 0
Mitotic Anaphase R-HSA-68882 9.877826e-03 2.005 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 1.200759e-02 1.921 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 1.200759e-02 1.921 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 1.200759e-02 1.921 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 1.200759e-02 1.921 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.085576e-02 1.964 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 1.148488e-02 1.940 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.148488e-02 1.940 0 0
Deubiquitination R-HSA-5688426 1.096996e-02 1.960 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.027512e-02 1.988 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.144288e-02 1.941 0 0
Signaling by Interleukins R-HSA-449147 1.143868e-02 1.942 0 0
MHC class II antigen presentation R-HSA-2132295 1.222936e-02 1.913 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.367957e-02 1.864 0 0
Cell-Cell communication R-HSA-1500931 1.299983e-02 1.886 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.381237e-02 1.860 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.487647e-02 1.828 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.503060e-02 1.823 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 1.515672e-02 1.819 0 0
Signal attenuation R-HSA-74749 1.688240e-02 1.773 0 0
Axonal growth stimulation R-HSA-209563 1.826601e-02 1.738 0 0
MAPK family signaling cascades R-HSA-5683057 1.850662e-02 1.733 0 0
Truncations of AMER1 destabilize the destruction complex R-HSA-5467348 2.046881e-02 1.689 0 0
APC truncation mutants have impaired AXIN binding R-HSA-5467337 2.046881e-02 1.689 0 0
AXIN missense mutants destabilize the destruction complex R-HSA-5467340 2.046881e-02 1.689 0 0
Signaling by APC mutants R-HSA-4839744 2.046881e-02 1.689 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 2.144009e-02 1.669 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 2.330490e-02 1.633 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 2.324931e-02 1.634 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 2.194985e-02 1.659 0 0
G2/M Transition R-HSA-69275 2.407130e-02 1.619 0 0
Interleukin-12 signaling R-HSA-9020591 2.407241e-02 1.618 0 0
Signaling by GSK3beta mutants R-HSA-5339716 2.444080e-02 1.612 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 2.444080e-02 1.612 0 0
Signaling by AMER1 mutants R-HSA-4839748 2.444080e-02 1.612 0 0
Signaling by AXIN mutants R-HSA-4839735 2.444080e-02 1.612 0 0
Vesicle-mediated transport R-HSA-5653656 2.448282e-02 1.611 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.561030e-02 1.592 0 0
RAF activation R-HSA-5673000 2.804746e-02 1.552 0 0
Mitotic G2-G2/M phases R-HSA-453274 2.590683e-02 1.587 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 2.866027e-02 1.543 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 2.866027e-02 1.543 0 0
Signaling by CTNNB1 phospho-site mutants R-HSA-4839743 2.879812e-02 1.541 0 0
CTNNB1 S45 mutants aren't phosphorylated R-HSA-5358751 2.879812e-02 1.541 0 0
CTNNB1 S37 mutants aren't phosphorylated R-HSA-5358749 2.879812e-02 1.541 0 0
CTNNB1 S33 mutants aren't phosphorylated R-HSA-5358747 2.879812e-02 1.541 0 0
CTNNB1 T41 mutants aren't phosphorylated R-HSA-5358752 2.879812e-02 1.541 0 0
Co-stimulation by CD28 R-HSA-389356 2.928309e-02 1.533 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 3.253996e-02 1.488 0 0
RAF/MAP kinase cascade R-HSA-5673001 3.240962e-02 1.489 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 3.253856e-02 1.488 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 3.154653e-02 1.501 0 0
FLT3 signaling in disease R-HSA-9682385 3.336096e-02 1.477 0 0
IRS activation R-HSA-74713 3.394359e-02 1.469 0 0
Inositol transporters R-HSA-429593 3.394359e-02 1.469 0 0
Co-inhibition by BTLA R-HSA-9927353 3.394359e-02 1.469 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.440069e-02 1.463 0 0
Regulation of TP53 Activity R-HSA-5633007 3.444926e-02 1.463 0 0
AURKA Activation by TPX2 R-HSA-8854518 3.460516e-02 1.461 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 3.865762e-02 1.413 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.612308e-02 1.442 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.623664e-02 1.441 0 0
Platelet activation, signaling and aggregation R-HSA-76002 3.681567e-02 1.434 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.899209e-02 1.409 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 3.927996e-02 1.406 0 0
Long-term potentiation R-HSA-9620244 3.987107e-02 1.399 0 0
Oncogenic MAPK signaling R-HSA-6802957 3.993821e-02 1.399 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 4.243319e-02 1.372 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 4.243319e-02 1.372 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 4.317499e-02 1.365 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 4.317499e-02 1.365 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 4.317499e-02 1.365 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 4.317499e-02 1.365 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 4.388651e-02 1.358 0 0
Beta-catenin phosphorylation cascade R-HSA-196299 4.414990e-02 1.355 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 4.414990e-02 1.355 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 5.000808e-02 1.301 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.000808e-02 1.301 0 0
Interleukin-12 family signaling R-HSA-447115 4.648484e-02 1.333 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 5.010241e-02 1.300 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 5.150084e-02 1.288 0 0
Signaling by RAF1 mutants R-HSA-9656223 5.285484e-02 1.277 0 0
MAP2K and MAPK activation R-HSA-5674135 5.285484e-02 1.277 0 0
Regulation of NFE2L2 gene expression R-HSA-9818749 5.321930e-02 1.274 0 0
Signaling by ERBB4 R-HSA-1236394 5.427303e-02 1.265 0 0
Ub-specific processing proteases R-HSA-5689880 5.606952e-02 1.251 0 0
Diseases of Telomere Maintenance R-HSA-9673013 7.859278e-02 1.105 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 7.859278e-02 1.105 0 0
Defective Inhibition of DNA Recombination at Telomere R-HSA-9670621 7.859278e-02 1.105 0 0
Alternative Lengthening of Telomeres (ALT) R-HSA-9006821 7.859278e-02 1.105 0 0
Defective DNA double strand break response due to BRCA1 loss of function R-HSA-9663199 7.859278e-02 1.105 0 0
Hereditary fructose intolerance R-HSA-5657560 7.859278e-02 1.105 0 0
Defective DNA double strand break response due to BARD1 loss of function R-HSA-9699150 7.859278e-02 1.105 0 0
Impaired BRCA2 binding to SEM1 (DSS1) R-HSA-9763198 7.859278e-02 1.105 0 0
Impaired BRCA2 translocation to the nucleus R-HSA-9709275 7.859278e-02 1.105 0 0
Defective Mismatch Repair Associated With MSH6 R-HSA-5632968 7.859278e-02 1.105 0 0
Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations R-HSA-9670613 7.859278e-02 1.105 0 0
Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations R-HSA-9670615 7.859278e-02 1.105 0 0
NFG and proNGF binds to p75NTR R-HSA-205017 1.155450e-01 0.937 0 0
XAV939 stabilizes AXIN R-HSA-5545619 1.155450e-01 0.937 0 0
TRAF3 deficiency - HSE R-HSA-5602571 1.155450e-01 0.937 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.155450e-01 0.937 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.510174e-01 0.821 0 0
Glycogen storage disease type 0 (muscle GYS1) R-HSA-3828062 1.510174e-01 0.821 0 0
Defective visual phototransduction due to STRA6 loss of function R-HSA-9918449 1.510174e-01 0.821 0 0
Glycogen storage disease type II (GAA) R-HSA-5357609 1.510174e-01 0.821 0 0
Glycogen storage disease type XV (GYG1) R-HSA-3814836 1.510174e-01 0.821 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 6.399671e-02 1.194 0 0
MET activates PTPN11 R-HSA-8865999 1.850692e-01 0.733 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 7.543246e-02 1.122 0 0
Formation of annular gap junctions R-HSA-196025 7.543246e-02 1.122 0 0
MET receptor recycling R-HSA-8875656 7.543246e-02 1.122 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 7.543246e-02 1.122 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 7.543246e-02 1.122 0 0
ARMS-mediated activation R-HSA-170984 8.745660e-02 1.058 0 0
Regulated proteolysis of p75NTR R-HSA-193692 8.745660e-02 1.058 0 0
Gap junction degradation R-HSA-190873 8.745660e-02 1.058 0 0
Inactivation of CDC42 and RAC1 R-HSA-428543 8.745660e-02 1.058 0 0
NADE modulates death signalling R-HSA-205025 2.177572e-01 0.662 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 2.177572e-01 0.662 0 0
NFE2L2 regulating ER-stress associated genes R-HSA-9818035 2.177572e-01 0.662 0 0
Nucleotide catabolism defects R-HSA-9735786 2.177572e-01 0.662 0 0
Defective LFNG causes SCDO3 R-HSA-5083630 2.177572e-01 0.662 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.000037e-01 1.000 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 1.000037e-01 1.000 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.130127e-01 0.947 0 0
NFE2L2 regulating TCA cycle genes R-HSA-9818025 2.491359e-01 0.604 0 0
NFE2L2 regulating inflammation associated genes R-HSA-9818026 2.491359e-01 0.604 0 0
G2 Phase R-HSA-68911 2.491359e-01 0.604 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 6.278725e-02 1.202 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.264265e-01 0.898 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 1.264265e-01 0.898 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.264265e-01 0.898 0 0
PKA activation in glucagon signalling R-HSA-164378 6.968821e-02 1.157 0 0
Impaired BRCA2 binding to PALB2 R-HSA-9709603 7.691528e-02 1.114 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.401917e-01 0.853 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.401917e-01 0.853 0 0
Loss of MECP2 binding ability to the NCoR/SMRT complex R-HSA-9022537 2.792578e-01 0.554 0 0
Defective homologous recombination repair (HRR) due to PALB2 loss of function R-HSA-9701193 8.445647e-02 1.073 0 0
Defective homologous recombination repair (HRR) due to BRCA1 loss of function R-HSA-9701192 8.445647e-02 1.073 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function R-HSA-9704646 8.445647e-02 1.073 0 0
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function R-HSA-9704331 8.445647e-02 1.073 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.542589e-01 0.812 0 0
Adenylate cyclase activating pathway R-HSA-170660 1.542589e-01 0.812 0 0
Signaling by LTK in cancer R-HSA-9842640 3.081731e-01 0.511 0 0
Erythropoietin activates STAT5 R-HSA-9027283 3.081731e-01 0.511 0 0
STAT5 Activation R-HSA-9645135 3.081731e-01 0.511 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 3.081731e-01 0.511 0 0
Erythropoietin activates RAS R-HSA-9027284 1.831171e-01 0.737 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 1.831171e-01 0.737 0 0
Deadenylation of mRNA R-HSA-429947 1.264203e-01 0.898 0 0
POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation R-HSA-2892245 3.359299e-01 0.474 0 0
PP2A-mediated dephosphorylation of key metabolic factors R-HSA-163767 3.359299e-01 0.474 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.359299e-01 0.474 0 0
Recycling of eIF2:GDP R-HSA-72731 3.359299e-01 0.474 0 0
Pre-NOTCH Processing in the Endoplasmic Reticulum R-HSA-1912399 3.359299e-01 0.474 0 0
Disinhibition of SNARE formation R-HSA-114516 3.359299e-01 0.474 0 0
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) R-HSA-5693554 1.355693e-01 0.868 0 0
Signaling downstream of RAS mutants R-HSA-9649948 7.324328e-02 1.135 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 1.545117e-01 0.811 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 1.545117e-01 0.811 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 1.545117e-01 0.811 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 1.545117e-01 0.811 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 1.545117e-01 0.811 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.276131e-01 0.643 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.276131e-01 0.643 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 3.625748e-01 0.441 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 3.625748e-01 0.441 0 0
HIV elongation arrest and recovery R-HSA-167287 1.642770e-01 0.784 0 0
Pausing and recovery of HIV elongation R-HSA-167290 1.642770e-01 0.784 0 0
Signaling by Erythropoietin R-HSA-9006335 1.742197e-01 0.759 0 0
Late endosomal microautophagy R-HSA-9615710 1.742197e-01 0.759 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 1.742197e-01 0.759 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 1.290580e-01 0.889 0 0
Centrosome maturation R-HSA-380287 5.713671e-02 1.243 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.576799e-01 0.589 0 0
NFE2L2 regulating MDR associated enzymes R-HSA-9818032 3.881522e-01 0.411 0 0
CASP8 activity is inhibited R-HSA-5218900 3.881522e-01 0.411 0 0
ALK mutants bind TKIs R-HSA-9700645 3.881522e-01 0.411 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 1.435557e-01 0.843 0 0
HIV Transcription Initiation R-HSA-167161 1.435557e-01 0.843 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 1.435557e-01 0.843 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 1.586581e-01 0.800 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 2.154915e-01 0.667 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.877981e-01 0.541 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.877981e-01 0.541 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 4.127047e-01 0.384 0 0
2-LTR circle formation R-HSA-164843 4.127047e-01 0.384 0 0
Folding of actin by CCT/TriC R-HSA-390450 4.127047e-01 0.384 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 1.743150e-01 0.759 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 2.261182e-01 0.646 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 2.261182e-01 0.646 0 0
Striated Muscle Contraction R-HSA-390522 2.261182e-01 0.646 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 2.261182e-01 0.646 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 3.028147e-01 0.519 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 2.368427e-01 0.626 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 2.368427e-01 0.626 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.069040e-01 0.971 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.987265e-01 0.702 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 2.476528e-01 0.606 0 0
FGFR2 alternative splicing R-HSA-6803529 3.177741e-01 0.498 0 0
Notch-HLH transcription pathway R-HSA-350054 3.177741e-01 0.498 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.362734e-01 0.360 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 3.326567e-01 0.478 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 3.326567e-01 0.478 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 2.327273e-01 0.633 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 3.474445e-01 0.459 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 2.032195e-01 0.692 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.414429e-01 0.617 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 2.915136e-01 0.535 0 0
Translation initiation complex formation R-HSA-72649 2.502316e-01 0.602 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 3.025783e-01 0.519 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 3.025783e-01 0.519 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.398033e-01 0.620 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 2.549143e-01 0.594 0 0
GABA B receptor activation R-HSA-977444 3.358463e-01 0.474 0 0
Activation of GABAB receptors R-HSA-991365 3.358463e-01 0.474 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 4.053439e-01 0.392 0 0
Formation of the Early Elongation Complex R-HSA-113418 4.053439e-01 0.392 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 4.194413e-01 0.377 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 3.093606e-01 0.510 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 3.800336e-01 0.420 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 4.333661e-01 0.363 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 4.471096e-01 0.350 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 4.471096e-01 0.350 0 0
Neutrophil degranulation R-HSA-6798695 1.300280e-01 0.886 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 3.683476e-01 0.434 0 0
mRNA 3'-end processing R-HSA-72187 4.449274e-01 0.352 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 3.972735e-01 0.401 0 0
Meiotic synapsis R-HSA-1221632 4.554964e-01 0.342 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.554964e-01 0.342 0 0
Transcription of the HIV genome R-HSA-167172 2.032195e-01 0.692 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 1.909093e-01 0.719 0 0
Signaling by EGFR in Cancer R-HSA-1643713 3.766723e-01 0.424 0 0
Nucleotide Excision Repair R-HSA-5696398 1.114278e-01 0.953 0 0
DAP12 signaling R-HSA-2424491 4.333661e-01 0.363 0 0
HIV Transcription Elongation R-HSA-167169 3.025783e-01 0.519 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 2.877981e-01 0.541 0 0
mRNA Capping R-HSA-72086 4.194413e-01 0.377 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 8.706537e-02 1.060 0 0
Telomere Extension By Telomerase R-HSA-171319 4.053439e-01 0.392 0 0
Ribosome-associated quality control R-HSA-9948299 4.489162e-01 0.348 0 0
Activation of the pre-replicative complex R-HSA-68962 1.843260e-01 0.734 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.154641e-01 0.938 0 0
DNA Damage Bypass R-HSA-73893 4.127616e-01 0.384 0 0
p75NTR regulates axonogenesis R-HSA-193697 8.745660e-02 1.058 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 3.025783e-01 0.519 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 4.140455e-01 0.383 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 1.264265e-01 0.898 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 2.126686e-01 0.672 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 6.968821e-02 1.157 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 7.324328e-02 1.135 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 7.324328e-02 1.135 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 1.079564e-01 0.967 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.139978e-01 0.943 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 4.049457e-01 0.393 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 3.702480e-01 0.432 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 2.692979e-01 0.570 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 7.543246e-02 1.122 0 0
DCC mediated attractive signaling R-HSA-418885 1.831171e-01 0.737 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.326567e-01 0.478 0 0
MET promotes cell motility R-HSA-8875878 2.804780e-01 0.552 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.855367e-01 0.544 0 0
Processing of DNA double-strand break ends R-HSA-5693607 3.014659e-01 0.521 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.855367e-01 0.544 0 0
Regulation of CDH11 function R-HSA-9762292 1.000037e-01 1.000 0 0
PI3K/AKT activation R-HSA-198203 1.000037e-01 1.000 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 3.359299e-01 0.474 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.727454e-01 0.564 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.727454e-01 0.564 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 3.177741e-01 0.498 0 0
LGI-ADAM interactions R-HSA-5682910 4.362734e-01 0.360 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 4.362734e-01 0.360 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 2.915136e-01 0.535 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 3.025783e-01 0.519 0 0
Attenuation phase R-HSA-3371568 3.025783e-01 0.519 0 0
Chaperone Mediated Autophagy R-HSA-9613829 6.968821e-02 1.157 0 0
Recycling pathway of L1 R-HSA-437239 7.776958e-02 1.109 0 0
Signaling by RAS mutants R-HSA-6802949 7.324328e-02 1.135 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 1.234077e-01 0.909 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.685007e-01 0.773 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 8.745660e-02 1.058 0 0
Regulation of gap junction activity R-HSA-191650 2.177572e-01 0.662 0 0
PKA activation R-HSA-163615 6.968821e-02 1.157 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 1.264203e-01 0.898 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 1.642770e-01 0.784 0 0
Translesion Synthesis by POLH R-HSA-110320 2.576799e-01 0.589 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 2.605290e-01 0.584 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 6.968821e-02 1.157 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 6.278725e-02 1.202 0 0
Regulation of signaling by CBL R-HSA-912631 7.691528e-02 1.114 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 2.476528e-01 0.606 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 3.683268e-01 0.434 0 0
Late Phase of HIV Life Cycle R-HSA-162599 1.256881e-01 0.901 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 2.804780e-01 0.552 0 0
Resolution of D-Loop Structures R-HSA-5693537 2.261182e-01 0.646 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.028147e-01 0.519 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.471096e-01 0.350 0 0
Homology Directed Repair R-HSA-5693538 1.777869e-01 0.750 0 0
TNFR1-mediated ceramide production R-HSA-5626978 2.177572e-01 0.662 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 1.000037e-01 1.000 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.491359e-01 0.604 0 0
SLC15A4:TASL-dependent IRF5 activation R-HSA-9860276 2.792578e-01 0.554 0 0
PTK6 Expression R-HSA-8849473 3.359299e-01 0.474 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 3.625748e-01 0.441 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.426267e-01 0.615 0 0
Resolution of D-loop Structures through Holliday Junction Intermediates R-HSA-5693568 2.154915e-01 0.667 0 0
Metabolism of non-coding RNA R-HSA-194441 1.429929e-01 0.845 0 0
snRNP Assembly R-HSA-191859 1.429929e-01 0.845 0 0
Tight junction interactions R-HSA-420029 3.621214e-01 0.441 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 3.358463e-01 0.474 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 2.243194e-01 0.649 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 2.323849e-01 0.634 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.683476e-01 0.434 0 0
Eukaryotic Translation Elongation R-HSA-156842 4.052716e-01 0.392 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.431920e-01 0.844 0 0
Rab regulation of trafficking R-HSA-9007101 2.918781e-01 0.535 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 1.184005e-01 0.927 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 1.152274e-01 0.938 0 0
Parasite infection R-HSA-9664407 1.152274e-01 0.938 0 0
Leishmania phagocytosis R-HSA-9664417 1.152274e-01 0.938 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 1.020672e-01 0.991 0 0
HSF1-dependent transactivation R-HSA-3371571 2.240913e-01 0.650 0 0
Meiosis R-HSA-1500620 3.332004e-01 0.477 0 0
Death Receptor Signaling R-HSA-73887 1.723919e-01 0.763 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 1.978251e-01 0.704 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.450766e-01 0.838 0 0
Cellular response to chemical stress R-HSA-9711123 3.993657e-01 0.399 0 0
EGFR downregulation R-HSA-182971 1.945823e-01 0.711 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.134972e-01 0.945 0 0
NRIF signals cell death from the nucleus R-HSA-205043 1.685817e-01 0.773 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 1.362282e-01 0.866 0 0
NRAGE signals death through JNK R-HSA-193648 1.249038e-01 0.903 0 0
HSF1 activation R-HSA-3371511 2.585364e-01 0.587 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.247543e-01 0.488 0 0
Signaling by WNT in cancer R-HSA-4791275 7.252321e-02 1.140 0 0
Keratinization R-HSA-6805567 4.455698e-01 0.351 0 0
RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression R-HSA-9933387 1.843260e-01 0.734 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.881522e-01 0.411 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 3.028147e-01 0.519 0 0
Chromosome Maintenance R-HSA-73886 3.175398e-01 0.498 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 2.126686e-01 0.672 0 0
Germ layer formation at gastrulation R-HSA-9754189 2.576799e-01 0.589 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.682168e-01 0.774 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 2.694819e-01 0.569 0 0
Nuclear Envelope Breakdown R-HSA-2980766 2.769722e-01 0.558 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 1.742197e-01 0.759 0 0
Mitophagy R-HSA-5205647 2.368427e-01 0.626 0 0
GPVI-mediated activation cascade R-HSA-114604 1.020672e-01 0.991 0 0
Cellular response to heat stress R-HSA-3371556 1.928062e-01 0.715 0 0
Manipulation of host energy metabolism R-HSA-9636667 1.155450e-01 0.937 0 0
Defective Mismatch Repair Associated With MSH2 R-HSA-5632928 1.155450e-01 0.937 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.510174e-01 0.821 0 0
Negative regulation of TCF-dependent signaling by DVL-interacting proteins R-HSA-5368598 1.850692e-01 0.733 0 0
Unwinding of DNA R-HSA-176974 8.745660e-02 1.058 0 0
Suppression of autophagy R-HSA-9636569 2.491359e-01 0.604 0 0
Signaling by LTK R-HSA-9842663 1.401917e-01 0.853 0 0
Ceramide signalling R-HSA-193681 2.792578e-01 0.554 0 0
Phosphorylation of Emi1 R-HSA-176417 2.792578e-01 0.554 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.792578e-01 0.554 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 1.542589e-01 0.812 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 1.978251e-01 0.704 0 0
Negative regulation of activity of TFAP2 (AP-2) family transcription factors R-HSA-8866904 3.625748e-01 0.441 0 0
Regulation by c-FLIP R-HSA-3371378 3.625748e-01 0.441 0 0
Co-stimulation by ICOS R-HSA-9927354 3.625748e-01 0.441 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 7.426516e-02 1.129 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 2.576799e-01 0.589 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 4.127047e-01 0.384 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 4.127047e-01 0.384 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 2.261182e-01 0.646 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 4.362734e-01 0.360 0 0
vRNP Assembly R-HSA-192905 4.362734e-01 0.360 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.037881e-01 0.984 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 2.804780e-01 0.552 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 2.859897e-01 0.544 0 0
Cristae formation R-HSA-8949613 3.910839e-01 0.408 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.620671e-01 0.790 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.053439e-01 0.392 0 0
Viral Messenger RNA Synthesis R-HSA-168325 3.132682e-01 0.504 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 2.556682e-01 0.592 0 0
Mitochondrial protein import R-HSA-1268020 3.224168e-01 0.492 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 4.194413e-01 0.377 0 0
Telomere Maintenance R-HSA-157579 2.831018e-01 0.548 0 0
Budding and maturation of HIV virion R-HSA-162588 4.471096e-01 0.350 0 0
COPI-mediated anterograde transport R-HSA-6807878 4.450040e-01 0.352 0 0
HIV Life Cycle R-HSA-162587 1.092182e-01 0.962 0 0
FGFR1 mutant receptor activation R-HSA-1839124 2.154915e-01 0.667 0 0
Extension of Telomeres R-HSA-180786 2.950488e-01 0.530 0 0
DNA Repair R-HSA-73894 2.192127e-01 0.659 0 0
Ephrin signaling R-HSA-3928664 6.968821e-02 1.157 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 2.576799e-01 0.589 0 0
Formation of the cornified envelope R-HSA-6809371 6.097212e-02 1.215 0 0
Heme signaling R-HSA-9707616 7.046851e-02 1.152 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 3.025783e-01 0.519 0 0
PTK6 Regulates Proteins Involved in RNA Processing R-HSA-8849468 2.491359e-01 0.604 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 9.229922e-02 1.035 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.625748e-01 0.441 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.807205e-01 0.552 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.664205e-01 0.779 0 0
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway R-HSA-5676594 1.542589e-01 0.812 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 1.945823e-01 0.711 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 3.621214e-01 0.441 0 0
Netrin-1 signaling R-HSA-373752 1.664205e-01 0.779 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 3.703720e-01 0.431 0 0
HIV Infection R-HSA-162906 3.148016e-01 0.502 0 0
Muscarinic acetylcholine receptors R-HSA-390648 2.491359e-01 0.604 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 1.685817e-01 0.773 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 3.359299e-01 0.474 0 0
Activation of PUMA and translocation to mitochondria R-HSA-139915 3.359299e-01 0.474 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.881522e-01 0.411 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 3.881522e-01 0.411 0 0
GPER1 signaling R-HSA-9634597 4.019062e-01 0.396 0 0
Meiotic recombination R-HSA-912446 4.342782e-01 0.362 0 0
Cilium Assembly R-HSA-5617833 2.414722e-01 0.617 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 1.542589e-01 0.812 0 0
Pyroptosis R-HSA-5620971 1.642770e-01 0.784 0 0
Acyl chain remodelling of PS R-HSA-1482801 3.621214e-01 0.441 0 0
Smooth Muscle Contraction R-HSA-445355 4.554964e-01 0.342 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 3.136618e-01 0.504 0 0
Cellular responses to stress R-HSA-2262752 2.594951e-01 0.586 0 0
Oncogene Induced Senescence R-HSA-2559585 2.476528e-01 0.606 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.264203e-01 0.898 0 0
Signaling by FGFR in disease R-HSA-1226099 2.473287e-01 0.607 0 0
UCH proteinases R-HSA-5689603 2.625559e-01 0.581 0 0
Platelet degranulation R-HSA-114608 2.297611e-01 0.639 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 7.060354e-02 1.151 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.435557e-01 0.843 0 0
Toll-like Receptor Cascades R-HSA-168898 3.589213e-01 0.445 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.510344e-01 0.821 0 0
G-protein mediated events R-HSA-112040 3.683268e-01 0.434 0 0
Diseases of Mismatch Repair (MMR) R-HSA-5423599 1.850692e-01 0.733 0 0
SLC-mediated bile acid transport R-HSA-9958517 7.543246e-02 1.122 0 0
p75NTR negatively regulates cell cycle via SC1 R-HSA-193670 2.177572e-01 0.662 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 2.792578e-01 0.554 0 0
Maturation of nucleoprotein R-HSA-9683610 1.542589e-01 0.812 0 0
Ca2+ activated K+ channels R-HSA-1296052 3.359299e-01 0.474 0 0
Synthesis of PIPs in the nucleus R-HSA-8847453 3.359299e-01 0.474 0 0
VLDL clearance R-HSA-8964046 3.359299e-01 0.474 0 0
Dimerization of procaspase-8 R-HSA-69416 3.625748e-01 0.441 0 0
TGFBR3 PTM regulation R-HSA-9839383 3.625748e-01 0.441 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.881522e-01 0.411 0 0
DNA strand elongation R-HSA-69190 2.049752e-01 0.688 0 0
Regulation of necroptotic cell death R-HSA-5675482 2.154915e-01 0.667 0 0
Cross-presentation of particulate exogenous antigens (phagosomes) R-HSA-1236973 4.127047e-01 0.384 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 1.743150e-01 0.759 0 0
RET signaling R-HSA-8853659 2.585364e-01 0.587 0 0
G2/M DNA damage checkpoint R-HSA-69473 2.473287e-01 0.607 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 3.910839e-01 0.408 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 3.690306e-01 0.433 0 0
Cellular responses to stimuli R-HSA-8953897 2.799462e-01 0.553 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 2.361939e-01 0.627 0 0
Leishmania infection R-HSA-9658195 1.775328e-01 0.751 0 0
Parasitic Infection Pathways R-HSA-9824443 1.775328e-01 0.751 0 0
FLT3 Signaling R-HSA-9607240 3.136618e-01 0.504 0 0
Autophagy R-HSA-9612973 1.061475e-01 0.974 0 0
Diseases of DNA repair R-HSA-9675135 1.823352e-01 0.739 0 0
Regulated Necrosis R-HSA-5218859 9.495275e-02 1.022 0 0
MyD88-independent TLR4 cascade R-HSA-166166 2.361939e-01 0.627 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 2.069187e-01 0.684 0 0
Prolonged ERK activation events R-HSA-169893 1.978251e-01 0.704 0 0
Neurexins and neuroligins R-HSA-6794361 4.449274e-01 0.352 0 0
Downstream signal transduction R-HSA-186763 1.945823e-01 0.711 0 0
Signaling by SCF-KIT R-HSA-1433557 1.586581e-01 0.800 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 2.323421e-01 0.634 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.831171e-01 0.737 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.766723e-01 0.424 0 0
Intra-Golgi traffic R-HSA-6811438 3.247543e-01 0.488 0 0
Degradation of CDH1 R-HSA-9766229 4.127616e-01 0.384 0 0
G2/M Checkpoints R-HSA-69481 1.329570e-01 0.876 0 0
Gap junction trafficking and regulation R-HSA-157858 4.127616e-01 0.384 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 8.745660e-02 1.058 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 8.445647e-02 1.073 0 0
Rap1 signalling R-HSA-392517 2.576799e-01 0.589 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.194413e-01 0.377 0 0
Selective autophagy R-HSA-9663891 3.652120e-01 0.437 0 0
Cellular response to starvation R-HSA-9711097 4.316144e-01 0.365 0 0
Post NMDA receptor activation events R-HSA-438064 1.027563e-01 0.988 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 1.256881e-01 0.901 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 2.804780e-01 0.552 0 0
Reproduction R-HSA-1474165 3.896480e-01 0.409 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 3.535207e-01 0.452 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.449643e-01 0.839 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 1.845658e-01 0.734 0 0
G alpha (12/13) signalling events R-HSA-416482 1.444412e-01 0.840 0 0
Glycolysis R-HSA-70171 1.737856e-01 0.760 0 0
Organelle biogenesis and maintenance R-HSA-1852241 2.347862e-01 0.629 0 0
ESR-mediated signaling R-HSA-8939211 3.628753e-01 0.440 0 0
Cell junction organization R-HSA-446728 3.384343e-01 0.471 0 0
Adrenoceptors R-HSA-390696 7.543246e-02 1.122 0 0
Regulation of HMOX1 expression and activity R-HSA-9707587 2.177572e-01 0.662 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.177572e-01 0.662 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.000037e-01 1.000 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.792578e-01 0.554 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 3.081731e-01 0.511 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.978251e-01 0.704 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.359299e-01 0.474 0 0
Alpha-defensins R-HSA-1462054 3.625748e-01 0.441 0 0
AMPK inhibits chREBP transcriptional activation activity R-HSA-163680 3.881522e-01 0.411 0 0
Signalling to ERKs R-HSA-187687 2.476528e-01 0.606 0 0
Bicarbonate transporters R-HSA-425381 4.362734e-01 0.360 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 3.910839e-01 0.408 0 0
DARPP-32 events R-HSA-180024 4.194413e-01 0.377 0 0
Signaling by ROBO receptors R-HSA-376176 3.033895e-01 0.518 0 0
ISG15 antiviral mechanism R-HSA-1169408 4.411446e-01 0.355 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.020728e-01 0.991 0 0
Immune System R-HSA-168256 1.058034e-01 0.976 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.766723e-01 0.424 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 3.909946e-01 0.408 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 3.683476e-01 0.434 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 1.970861e-01 0.705 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.136618e-01 0.504 0 0
Platelet sensitization by LDL R-HSA-432142 6.968821e-02 1.157 0 0
Regulation of NPAS4 gene transcription R-HSA-9768777 3.881522e-01 0.411 0 0
GP1b-IX-V activation signalling R-HSA-430116 3.881522e-01 0.411 0 0
Activation of ATR in response to replication stress R-HSA-176187 2.154915e-01 0.667 0 0
Transport of RCbl within the body R-HSA-9758890 4.362734e-01 0.360 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 8.692465e-02 1.061 0 0
Macroautophagy R-HSA-1632852 3.218908e-01 0.492 0 0
Calmodulin induced events R-HSA-111933 1.020672e-01 0.991 0 0
Hemostasis R-HSA-109582 2.050142e-01 0.688 0 0
Maturation of nucleoprotein R-HSA-9694631 2.576799e-01 0.589 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 1.308107e-01 0.883 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.235543e-01 0.373 0 0
Adaptive Immune System R-HSA-1280218 2.693100e-01 0.570 0 0
Protein-protein interactions at synapses R-HSA-6794362 3.332004e-01 0.477 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 4.411446e-01 0.355 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 2.543771e-01 0.595 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.028147e-01 0.519 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 2.729570e-01 0.564 0 0
CaM pathway R-HSA-111997 1.020672e-01 0.991 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.399671e-02 1.194 0 0
Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence R-HSA-9825895 7.543246e-02 1.122 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 8.745660e-02 1.058 0 0
Polo-like kinase mediated events R-HSA-156711 6.968821e-02 1.157 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 2.792578e-01 0.554 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.542589e-01 0.812 0 0
Nef and signal transduction R-HSA-164944 3.081731e-01 0.511 0 0
Syndecan interactions R-HSA-3000170 1.175048e-01 0.930 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 3.881522e-01 0.411 0 0
LDL clearance R-HSA-8964038 3.177741e-01 0.498 0 0
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 4.362734e-01 0.360 0 0
Synthesis of PIPs at the ER membrane R-HSA-1483248 4.362734e-01 0.360 0 0
SARS-CoV-2 modulates autophagy R-HSA-9754560 4.362734e-01 0.360 0 0
Pyrimidine salvage R-HSA-73614 4.053439e-01 0.392 0 0
Aquaporin-mediated transport R-HSA-445717 3.132682e-01 0.504 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 3.224168e-01 0.492 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.900621e-01 0.538 0 0
Glucose metabolism R-HSA-70326 2.918781e-01 0.535 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.900621e-01 0.538 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.900621e-01 0.538 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.369361e-01 0.863 0 0
Signaling by PDGF R-HSA-186797 3.224168e-01 0.492 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.936036e-01 0.532 0 0
Diseases of programmed cell death R-HSA-9645723 3.652120e-01 0.437 0 0
Cellular Senescence R-HSA-2559583 4.276520e-01 0.369 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 4.194413e-01 0.377 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 3.755515e-01 0.425 0 0
Interleukin-2 family signaling R-HSA-451927 1.290580e-01 0.889 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.039153e-01 0.983 0 0
Ca-dependent events R-HSA-111996 1.510344e-01 0.821 0 0
Signaling by NTRKs R-HSA-166520 2.436049e-01 0.613 0 0
Neurodegenerative Diseases R-HSA-8863678 3.474445e-01 0.459 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 3.474445e-01 0.459 0 0
DAG and IP3 signaling R-HSA-1489509 1.743150e-01 0.759 0 0
Generation of second messenger molecules R-HSA-202433 3.025783e-01 0.519 0 0
Response of endothelial cells to shear stress R-HSA-9860931 3.324668e-01 0.478 0 0
Cytokine Signaling in Immune system R-HSA-1280215 9.197779e-02 1.036 0 0
Influenza Infection R-HSA-168255 2.955296e-01 0.529 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.978251e-01 0.704 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.020672e-01 0.991 0 0
Zinc influx into cells by the SLC39 gene family R-HSA-442380 3.881522e-01 0.411 0 0
Cellular response to mitochondrial stress R-HSA-9840373 3.881522e-01 0.411 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 4.127047e-01 0.384 0 0
Metalloprotease DUBs R-HSA-5689901 3.766723e-01 0.424 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 3.910839e-01 0.408 0 0
Potential therapeutics for SARS R-HSA-9679191 2.540364e-01 0.595 0 0
PI3K Cascade R-HSA-109704 4.235543e-01 0.373 0 0
PLC beta mediated events R-HSA-112043 3.132682e-01 0.504 0 0
Intracellular signaling by second messengers R-HSA-9006925 2.335591e-01 0.632 0 0
Zinc transporters R-HSA-435354 1.685817e-01 0.773 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.355693e-01 0.868 0 0
Sensory processing of sound R-HSA-9659379 6.951325e-02 1.158 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 3.621214e-01 0.441 0 0
Integration of energy metabolism R-HSA-163685 4.358016e-01 0.361 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 3.224168e-01 0.492 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.148598e-01 0.382 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 4.115726e-01 0.386 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 2.680026e-01 0.572 0 0
Zinc efflux and compartmentalization by the SLC30 family R-HSA-435368 2.491359e-01 0.604 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.792578e-01 0.554 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.220511e-01 0.913 0 0
PECAM1 interactions R-HSA-210990 4.362734e-01 0.360 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.777869e-01 0.750 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 3.910839e-01 0.408 0 0
Interleukin-1 family signaling R-HSA-446652 1.640911e-01 0.785 0 0
Amine ligand-binding receptors R-HSA-375280 3.579929e-01 0.446 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 2.980987e-01 0.526 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 2.426267e-01 0.615 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 3.621214e-01 0.441 0 0
Butyrophilin (BTN) family interactions R-HSA-8851680 8.745660e-02 1.058 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 2.491359e-01 0.604 0 0
Displacement of DNA glycosylase by APEX1 R-HSA-110357 3.359299e-01 0.474 0 0
Assembly Of The HIV Virion R-HSA-175474 3.028147e-01 0.519 0 0
Gluconeogenesis R-HSA-70263 4.019062e-01 0.396 0 0
PI Metabolism R-HSA-1483255 1.845658e-01 0.734 0 0
CD163 mediating an anti-inflammatory response R-HSA-9662834 4.362734e-01 0.360 0 0
Constitutive Signaling by AKT1 E17K in Cancer R-HSA-5674400 3.326567e-01 0.478 0 0
SARS-CoV-2 Infection R-HSA-9694516 2.578513e-01 0.589 0 0
Growth hormone receptor signaling R-HSA-982772 1.175048e-01 0.930 0 0
Signaling by Leptin R-HSA-2586552 1.000037e-01 1.000 0 0
Specification of primordial germ cells R-HSA-9827857 2.276131e-01 0.643 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 2.426267e-01 0.615 0 0
Interleukin-2 signaling R-HSA-9020558 4.362734e-01 0.360 0 0
Mitochondrial calcium ion transport R-HSA-8949215 1.004305e-01 0.998 0 0
Defective RIPK1-mediated regulated necrosis R-HSA-9693928 4.127047e-01 0.384 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.028147e-01 0.519 0 0
Mitochondrial biogenesis R-HSA-1592230 4.473824e-01 0.349 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 1.616914e-01 0.791 0 0
Interleukin-7 signaling R-HSA-1266695 3.621214e-01 0.441 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 2.950488e-01 0.530 0 0
rRNA processing R-HSA-72312 4.563454e-01 0.341 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 4.588977e-01 0.338 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.588977e-01 0.338 0 0
NF-kB is activated and signals survival R-HSA-209560 4.588977e-01 0.338 0 0
Plasmalogen biosynthesis R-HSA-75896 4.588977e-01 0.338 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 4.588977e-01 0.338 0 0
ERKs are inactivated R-HSA-202670 4.588977e-01 0.338 0 0
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis R-HSA-9623433 4.588977e-01 0.338 0 0
Activation of RAC1 R-HSA-428540 4.588977e-01 0.338 0 0
Integration of provirus R-HSA-162592 4.588977e-01 0.338 0 0
G0 and Early G1 R-HSA-1538133 4.606639e-01 0.337 0 0
Post-translational protein phosphorylation R-HSA-8957275 4.607232e-01 0.337 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 4.615856e-01 0.336 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 4.615856e-01 0.336 0 0
Mitotic Prophase R-HSA-68875 4.686533e-01 0.329 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 4.740220e-01 0.324 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 4.740220e-01 0.324 0 0
Regulation of TP53 Activity through Acetylation R-HSA-6804758 4.740220e-01 0.324 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 4.740220e-01 0.324 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.763737e-01 0.322 0 0
G alpha (z) signalling events R-HSA-418597 4.763737e-01 0.322 0 0
Muscle contraction R-HSA-397014 4.779092e-01 0.321 0 0
NOTCH2 intracellular domain regulates transcription R-HSA-2197563 4.806152e-01 0.318 0 0
p75NTR recruits signalling complexes R-HSA-209543 4.806152e-01 0.318 0 0
GRB2 events in EGFR signaling R-HSA-179812 4.806152e-01 0.318 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.806152e-01 0.318 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 4.806152e-01 0.318 0 0
IRAK1 recruits IKK complex R-HSA-937039 4.806152e-01 0.318 0 0
Polymerase switching R-HSA-69091 4.806152e-01 0.318 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 4.806152e-01 0.318 0 0
Leading Strand Synthesis R-HSA-69109 4.806152e-01 0.318 0 0
VLDLR internalisation and degradation R-HSA-8866427 4.806152e-01 0.318 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 4.806152e-01 0.318 0 0
MET activates RAS signaling R-HSA-8851805 4.806152e-01 0.318 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 4.806152e-01 0.318 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 4.806152e-01 0.318 0 0
Regulation of IFNG signaling R-HSA-877312 4.806152e-01 0.318 0 0
Interleukin-15 signaling R-HSA-8983432 4.806152e-01 0.318 0 0
Pervasive developmental disorders R-HSA-9005895 4.806152e-01 0.318 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 4.806152e-01 0.318 0 0
Disorders of Nervous System Development R-HSA-9697154 4.806152e-01 0.318 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 4.806152e-01 0.318 0 0
AKT phosphorylates targets in the cytosol R-HSA-198323 4.806152e-01 0.318 0 0
OAS antiviral response R-HSA-8983711 4.806152e-01 0.318 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 4.827110e-01 0.316 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 4.827110e-01 0.316 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.866727e-01 0.313 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.866727e-01 0.313 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 4.866727e-01 0.313 0 0
TNF signaling R-HSA-75893 4.866727e-01 0.313 0 0
Signaling by EGFR R-HSA-177929 4.866727e-01 0.313 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 4.866727e-01 0.313 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 4.871779e-01 0.312 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 4.871779e-01 0.312 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 4.871779e-01 0.312 0 0
Glutamate and glutamine metabolism R-HSA-8964539 4.871779e-01 0.312 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 4.917486e-01 0.308 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.917486e-01 0.308 0 0
SARS-CoV Infections R-HSA-9679506 4.930266e-01 0.307 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 4.941020e-01 0.306 0 0
Regulation of CDH1 Function R-HSA-9764561 4.968727e-01 0.304 0 0
IRS-mediated signalling R-HSA-112399 4.968727e-01 0.304 0 0
Dual Incision in GG-NER R-HSA-5696400 5.001264e-01 0.301 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 5.001264e-01 0.301 0 0
Signaling by NOTCH2 R-HSA-1980145 5.001264e-01 0.301 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 5.001264e-01 0.301 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 5.001264e-01 0.301 0 0
Nuclear import of Rev protein R-HSA-180746 5.001264e-01 0.301 0 0
BMAL1:CLOCK,NPAS2 activates circadian expression R-HSA-1368108 5.001264e-01 0.301 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 5.014624e-01 0.300 0 0
Diseases of nucleotide metabolism R-HSA-9735804 5.014624e-01 0.300 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 5.014624e-01 0.300 0 0
PI5P Regulates TP53 Acetylation R-HSA-6811555 5.014624e-01 0.300 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 5.014624e-01 0.300 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 5.014624e-01 0.300 0 0
Regulation of TP53 Activity through Association with Co-factors R-HSA-6804759 5.014624e-01 0.300 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 5.014624e-01 0.300 0 0
Dual incision in TC-NER R-HSA-6782135 5.069699e-01 0.295 0 0
Opioid Signalling R-HSA-111885 5.070170e-01 0.295 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 5.070498e-01 0.295 0 0
G1/S Transition R-HSA-69206 5.104655e-01 0.292 0 0
Cytoprotection by HMOX1 R-HSA-9707564 5.112893e-01 0.291 0 0
RSV-host interactions R-HSA-9833110 5.145826e-01 0.289 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.169606e-01 0.287 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 5.169606e-01 0.287 0 0
S Phase R-HSA-69242 5.197022e-01 0.284 0 0
Retrograde neurotrophin signalling R-HSA-177504 5.214741e-01 0.283 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 5.214741e-01 0.283 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 5.214741e-01 0.283 0 0
Signaling by FGFR4 in disease R-HSA-5655291 5.214741e-01 0.283 0 0
TP53 Regulates Transcription of Death Receptors and Ligands R-HSA-6803211 5.214741e-01 0.283 0 0
cGMP effects R-HSA-418457 5.214741e-01 0.283 0 0
CRMPs in Sema3A signaling R-HSA-399956 5.214741e-01 0.283 0 0
P2Y receptors R-HSA-417957 5.214741e-01 0.283 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 5.214741e-01 0.283 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 5.253833e-01 0.280 0 0
G1/S-Specific Transcription R-HSA-69205 5.253833e-01 0.280 0 0
FGFR2 mutant receptor activation R-HSA-1839126 5.253833e-01 0.280 0 0
RAB geranylgeranylation R-HSA-8873719 5.268415e-01 0.278 0 0
GABA receptor activation R-HSA-977443 5.268415e-01 0.278 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 5.282060e-01 0.277 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.366095e-01 0.270 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.366095e-01 0.270 0 0
Nucleotide salvage R-HSA-8956321 5.366095e-01 0.270 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.366095e-01 0.270 0 0
MAP kinase activation R-HSA-450294 5.366095e-01 0.270 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 5.376848e-01 0.269 0 0
Voltage gated Potassium channels R-HSA-1296072 5.376848e-01 0.269 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 5.376848e-01 0.269 0 0
Ovarian tumor domain proteases R-HSA-5689896 5.376848e-01 0.269 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 5.376848e-01 0.269 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 5.384528e-01 0.269 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 5.406836e-01 0.267 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 5.406836e-01 0.267 0 0
p75NTR signals via NF-kB R-HSA-193639 5.406836e-01 0.267 0 0
Translesion synthesis by REV1 R-HSA-110312 5.406836e-01 0.267 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 5.406836e-01 0.267 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 5.406836e-01 0.267 0 0
SHC1 events in EGFR signaling R-HSA-180336 5.406836e-01 0.267 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 5.406836e-01 0.267 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 5.406836e-01 0.267 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 5.406836e-01 0.267 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 5.406836e-01 0.267 0 0
Spry regulation of FGF signaling R-HSA-1295596 5.406836e-01 0.267 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 5.406836e-01 0.267 0 0
Formation of the anterior neural plate R-HSA-9823739 5.406836e-01 0.267 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 5.448325e-01 0.264 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.462616e-01 0.263 0 0
NCAM signaling for neurite out-growth R-HSA-375165 5.462616e-01 0.263 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 5.497646e-01 0.260 0 0
Purine salvage R-HSA-74217 5.497646e-01 0.260 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 5.569014e-01 0.254 0 0
Translesion synthesis by POLI R-HSA-5656121 5.591232e-01 0.252 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.591232e-01 0.252 0 0
Phosphorylation of the APC/C R-HSA-176412 5.591232e-01 0.252 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.591232e-01 0.252 0 0
Activation of SMO R-HSA-5635838 5.591232e-01 0.252 0 0
WNT5:FZD7-mediated leishmania damping R-HSA-9673324 5.591232e-01 0.252 0 0
Killing mechanisms R-HSA-9664420 5.591232e-01 0.252 0 0
Induction of Cell-Cell Fusion R-HSA-9733458 5.591232e-01 0.252 0 0
Fructose catabolism R-HSA-70350 5.591232e-01 0.252 0 0
Negative regulation of FLT3 R-HSA-9706369 5.591232e-01 0.252 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 5.591232e-01 0.252 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 5.591232e-01 0.252 0 0
Peptide chain elongation R-HSA-156902 5.611515e-01 0.251 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 5.616208e-01 0.251 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 5.616208e-01 0.251 0 0
Plasma lipoprotein clearance R-HSA-8964043 5.616208e-01 0.251 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 5.616208e-01 0.251 0 0
Signaling by ALK R-HSA-201556 5.616208e-01 0.251 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 5.616208e-01 0.251 0 0
Circadian clock R-HSA-9909396 5.641701e-01 0.249 0 0
Insulin receptor signalling cascade R-HSA-74751 5.652083e-01 0.248 0 0
IGF1R signaling cascade R-HSA-2428924 5.652083e-01 0.248 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 5.732124e-01 0.242 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 5.732124e-01 0.242 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 5.732518e-01 0.242 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 5.732518e-01 0.242 0 0
Diseases of Immune System R-HSA-5260271 5.732518e-01 0.242 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 5.732518e-01 0.242 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 5.732518e-01 0.242 0 0
Aggrephagy R-HSA-9646399 5.732518e-01 0.242 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 5.732518e-01 0.242 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 5.744984e-01 0.241 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 5.761219e-01 0.239 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 5.768235e-01 0.239 0 0
Translesion synthesis by POLK R-HSA-5655862 5.768235e-01 0.239 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 5.768235e-01 0.239 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 5.768235e-01 0.239 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 5.768235e-01 0.239 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 5.768235e-01 0.239 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 5.768235e-01 0.239 0 0
Synthesis of PG R-HSA-1483148 5.768235e-01 0.239 0 0
Disorders of Developmental Biology R-HSA-9675151 5.768235e-01 0.239 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 5.768235e-01 0.239 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 5.768235e-01 0.239 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 5.802185e-01 0.236 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 5.846565e-01 0.233 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 5.846565e-01 0.233 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 5.850204e-01 0.233 0 0
Disease R-HSA-1643685 5.885842e-01 0.230 0 0
Innate Immune System R-HSA-168249 5.898437e-01 0.229 0 0
DNA Double Strand Break Response R-HSA-5693606 5.927024e-01 0.227 0 0
Signaling by TGFB family members R-HSA-9006936 5.927784e-01 0.227 0 0
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) R-HSA-5358565 5.938142e-01 0.226 0 0
Glycogen storage diseases R-HSA-3229121 5.938142e-01 0.226 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 5.938142e-01 0.226 0 0
Regulation of NPAS4 gene expression R-HSA-9768759 5.938142e-01 0.226 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 5.938142e-01 0.226 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 5.942248e-01 0.226 0 0
Telomere C-strand (Lagging Strand) Synthesis R-HSA-174417 5.958345e-01 0.225 0 0
Translation of Structural Proteins R-HSA-9683701 5.958345e-01 0.225 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 6.067855e-01 0.217 0 0
MTOR signalling R-HSA-165159 6.067855e-01 0.217 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 6.067855e-01 0.217 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 6.081198e-01 0.216 0 0
GAB1 signalosome R-HSA-180292 6.101238e-01 0.215 0 0
PCNA-Dependent Long Patch Base Excision Repair R-HSA-5651801 6.101238e-01 0.215 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 6.101238e-01 0.215 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 6.101238e-01 0.215 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 6.101238e-01 0.215 0 0
Mismatch Repair R-HSA-5358508 6.101238e-01 0.215 0 0
Tie2 Signaling R-HSA-210993 6.101238e-01 0.215 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 6.101238e-01 0.215 0 0
Nucleotide-like (purinergic) receptors R-HSA-418038 6.101238e-01 0.215 0 0
Apoptotic factor-mediated response R-HSA-111471 6.101238e-01 0.215 0 0
Collagen formation R-HSA-1474290 6.156425e-01 0.211 0 0
Defective pyroptosis R-HSA-9710421 6.175098e-01 0.209 0 0
TBC/RABGAPs R-HSA-8854214 6.175098e-01 0.209 0 0
Response of Mtb to phagocytosis R-HSA-9637690 6.175098e-01 0.209 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 6.190459e-01 0.208 0 0
Interleukin-17 signaling R-HSA-448424 6.190459e-01 0.208 0 0
Neuronal System R-HSA-112316 6.222027e-01 0.206 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 6.230747e-01 0.205 0 0
Pre-NOTCH Processing in Golgi R-HSA-1912420 6.257794e-01 0.204 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 6.257794e-01 0.204 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 6.257794e-01 0.204 0 0
E2F mediated regulation of DNA replication R-HSA-113510 6.257794e-01 0.204 0 0
The NLRP3 inflammasome R-HSA-844456 6.257794e-01 0.204 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 6.257794e-01 0.204 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 6.257794e-01 0.204 0 0
STING mediated induction of host immune responses R-HSA-1834941 6.257794e-01 0.204 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 6.257794e-01 0.204 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 6.275658e-01 0.202 0 0
Regulation of mitotic cell cycle R-HSA-453276 6.275658e-01 0.202 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 6.275658e-01 0.202 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 6.275658e-01 0.202 0 0
DAP12 interactions R-HSA-2172127 6.280078e-01 0.202 0 0
Gap junction trafficking R-HSA-190828 6.280078e-01 0.202 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.304155e-01 0.200 0 0
Eukaryotic Translation Termination R-HSA-72764 6.304155e-01 0.200 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 6.359535e-01 0.197 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 6.359535e-01 0.197 0 0
Phospholipid metabolism R-HSA-1483257 6.376200e-01 0.195 0 0
Potassium Channels R-HSA-1296071 6.376641e-01 0.195 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 6.382805e-01 0.195 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 6.408073e-01 0.193 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 6.408073e-01 0.193 0 0
Glycogen synthesis R-HSA-3322077 6.408073e-01 0.193 0 0
Negative regulation of MET activity R-HSA-6807004 6.408073e-01 0.193 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 6.408073e-01 0.193 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 6.408073e-01 0.193 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.448198e-01 0.191 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 6.473187e-01 0.189 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 6.483290e-01 0.188 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.483290e-01 0.188 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 6.483290e-01 0.188 0 0
Regulation of TNFR1 signaling R-HSA-5357905 6.483290e-01 0.188 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 6.483290e-01 0.188 0 0
Regulation of pyruvate metabolism R-HSA-9861718 6.483290e-01 0.188 0 0
Signaling by TGFBR3 R-HSA-9839373 6.483290e-01 0.188 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 6.483290e-01 0.188 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 6.552326e-01 0.184 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 6.552326e-01 0.184 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 6.552326e-01 0.184 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.552326e-01 0.184 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 6.552326e-01 0.184 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 6.552326e-01 0.184 0 0
Lagging Strand Synthesis R-HSA-69186 6.552326e-01 0.184 0 0
Signalling to RAS R-HSA-167044 6.552326e-01 0.184 0 0
ERK/MAPK targets R-HSA-198753 6.552326e-01 0.184 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 6.552326e-01 0.184 0 0
Basigin interactions R-HSA-210991 6.552326e-01 0.184 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 6.552326e-01 0.184 0 0
Early Phase of HIV Life Cycle R-HSA-162594 6.552326e-01 0.184 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 6.581548e-01 0.182 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 6.581548e-01 0.182 0 0
Synthesis of PC R-HSA-1483191 6.581548e-01 0.182 0 0
HATs acetylate histones R-HSA-3214847 6.588496e-01 0.181 0 0
Chromatin organization R-HSA-4839726 6.622542e-01 0.179 0 0
Hedgehog 'off' state R-HSA-5610787 6.657227e-01 0.177 0 0
Host Interactions of HIV factors R-HSA-162909 6.660614e-01 0.176 0 0
NGF-stimulated transcription R-HSA-9031628 6.677594e-01 0.175 0 0
Metal ion SLC transporters R-HSA-425410 6.677594e-01 0.175 0 0
ER to Golgi Anterograde Transport R-HSA-199977 6.678021e-01 0.175 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.681747e-01 0.175 0 0
Signaling by NOTCH1 R-HSA-1980143 6.681747e-01 0.175 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 6.690794e-01 0.175 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 6.690794e-01 0.175 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 6.690794e-01 0.175 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 6.690794e-01 0.175 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 6.690794e-01 0.175 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 6.690794e-01 0.175 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.690794e-01 0.175 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 6.690794e-01 0.175 0 0
Signaling by PDGFR in disease R-HSA-9671555 6.690794e-01 0.175 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 6.690794e-01 0.175 0 0
Ribavirin ADME R-HSA-9755088 6.690794e-01 0.175 0 0
Selenocysteine synthesis R-HSA-2408557 6.725007e-01 0.172 0 0
Interleukin-1 signaling R-HSA-9020702 6.725007e-01 0.172 0 0
Developmental Biology R-HSA-1266738 6.803488e-01 0.167 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 6.823709e-01 0.166 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.823709e-01 0.166 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 6.823709e-01 0.166 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 6.823709e-01 0.166 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 6.823709e-01 0.166 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 6.823709e-01 0.166 0 0
Fructose metabolism R-HSA-5652084 6.823709e-01 0.166 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 6.823709e-01 0.166 0 0
mTORC1-mediated signalling R-HSA-166208 6.823709e-01 0.166 0 0
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain R-HSA-6803205 6.823709e-01 0.166 0 0
Signaling by KIT in disease R-HSA-9669938 6.823709e-01 0.166 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 6.823709e-01 0.166 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.823709e-01 0.166 0 0
RNA Polymerase I Transcription R-HSA-73864 6.834848e-01 0.165 0 0
PCP/CE pathway R-HSA-4086400 6.834848e-01 0.165 0 0
SLC-mediated transport of organic anions R-HSA-9955298 6.834848e-01 0.165 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 6.841428e-01 0.165 0 0
Viral mRNA Translation R-HSA-192823 6.857704e-01 0.164 0 0
Regulation of RAS by GAPs R-HSA-5658442 6.863134e-01 0.163 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 6.951207e-01 0.158 0 0
G beta:gamma signalling through PI3Kgamma R-HSA-392451 6.951293e-01 0.158 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 6.951293e-01 0.158 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 6.951293e-01 0.158 0 0
Organic anion transport by SLCO transporters R-HSA-879518 6.951293e-01 0.158 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.951293e-01 0.158 0 0
Interleukin-20 family signaling R-HSA-8854691 6.951293e-01 0.158 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 6.951293e-01 0.158 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 6.952671e-01 0.158 0 0
The phototransduction cascade R-HSA-2514856 6.952671e-01 0.158 0 0
Signaling by MET R-HSA-6806834 6.982625e-01 0.156 0 0
Signaling by FGFR2 R-HSA-5654738 6.982625e-01 0.156 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 6.982625e-01 0.156 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 6.982625e-01 0.156 0 0
PKR-mediated signaling R-HSA-9833482 6.982625e-01 0.156 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 7.040084e-01 0.152 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 7.040084e-01 0.152 0 0
Orc1 removal from chromatin R-HSA-68949 7.040084e-01 0.152 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 7.040084e-01 0.152 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.040084e-01 0.152 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 7.073759e-01 0.150 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 7.073759e-01 0.150 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 7.073759e-01 0.150 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 7.073759e-01 0.150 0 0
Platelet homeostasis R-HSA-418346 7.111600e-01 0.148 0 0
SARS-CoV-1-host interactions R-HSA-9692914 7.111600e-01 0.148 0 0
Chromatin modifying enzymes R-HSA-3247509 7.118001e-01 0.148 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 7.125400e-01 0.147 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 7.172679e-01 0.144 0 0
Synthesis of DNA R-HSA-69239 7.172679e-01 0.144 0 0
Gene Silencing by RNA R-HSA-211000 7.172679e-01 0.144 0 0
Adipogenesis R-HSA-9843745 7.182882e-01 0.144 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 7.191314e-01 0.143 0 0
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits R-HSA-997272 7.191314e-01 0.143 0 0
G protein gated Potassium channels R-HSA-1296059 7.191314e-01 0.143 0 0
Activation of G protein gated Potassium channels R-HSA-1296041 7.191314e-01 0.143 0 0
Polymerase switching on the C-strand of the telomere R-HSA-174411 7.191314e-01 0.143 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 7.191314e-01 0.143 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 7.191314e-01 0.143 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 7.191314e-01 0.143 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 7.191314e-01 0.143 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 7.191314e-01 0.143 0 0
Retinoid cycle disease events R-HSA-2453864 7.191314e-01 0.143 0 0
Diseases associated with visual transduction R-HSA-2474795 7.191314e-01 0.143 0 0
Diseases of the neuronal system R-HSA-9675143 7.191314e-01 0.143 0 0
Laminin interactions R-HSA-3000157 7.191314e-01 0.143 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 7.194384e-01 0.143 0 0
TCF dependent signaling in response to WNT R-HSA-201681 7.197289e-01 0.143 0 0
Stimuli-sensing channels R-HSA-2672351 7.232802e-01 0.141 0 0
Metabolism of RNA R-HSA-8953854 7.246742e-01 0.140 0 0
MET activates PTK2 signaling R-HSA-8874081 7.304153e-01 0.136 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 7.304153e-01 0.136 0 0
Resolution of AP sites via the multiple-nucleotide patch replacement pathway R-HSA-110373 7.304153e-01 0.136 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 7.304153e-01 0.136 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 7.304153e-01 0.136 0 0
TRP channels R-HSA-3295583 7.304153e-01 0.136 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 7.304153e-01 0.136 0 0
Suppression of phagosomal maturation R-HSA-9637687 7.304153e-01 0.136 0 0
TCR signaling R-HSA-202403 7.350192e-01 0.134 0 0
Ion homeostasis R-HSA-5578775 7.369045e-01 0.133 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 7.369045e-01 0.133 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 7.412465e-01 0.130 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.412465e-01 0.130 0 0
Signaling by BMP R-HSA-201451 7.412465e-01 0.130 0 0
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release R-HSA-6803204 7.412465e-01 0.130 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 7.412465e-01 0.130 0 0
Processive synthesis on the C-strand of the telomere R-HSA-174414 7.412465e-01 0.130 0 0
Triglyceride biosynthesis R-HSA-75109 7.412465e-01 0.130 0 0
Insulin processing R-HSA-264876 7.412465e-01 0.130 0 0
Dectin-2 family R-HSA-5621480 7.446257e-01 0.128 0 0
Transmission across Chemical Synapses R-HSA-112315 7.458023e-01 0.127 0 0
FCERI mediated MAPK activation R-HSA-2871796 7.463795e-01 0.127 0 0
Viral Infection Pathways R-HSA-9824446 7.474915e-01 0.126 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 7.516432e-01 0.124 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 7.516432e-01 0.124 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.516432e-01 0.124 0 0
Inflammasomes R-HSA-622312 7.516432e-01 0.124 0 0
Signaling by WNT R-HSA-195721 7.520786e-01 0.124 0 0
Pyruvate metabolism R-HSA-70268 7.521384e-01 0.124 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 7.521519e-01 0.124 0 0
Signaling by Hedgehog R-HSA-5358351 7.596093e-01 0.119 0 0
Termination of translesion DNA synthesis R-HSA-5656169 7.616227e-01 0.118 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.616227e-01 0.118 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 7.616227e-01 0.118 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 7.616227e-01 0.118 0 0
Regulation of PTEN gene transcription R-HSA-8943724 7.666321e-01 0.115 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 7.666321e-01 0.115 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 7.666321e-01 0.115 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 7.666321e-01 0.115 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 7.666321e-01 0.115 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 7.666321e-01 0.115 0 0
mRNA Splicing - Major Pathway R-HSA-72163 7.680002e-01 0.115 0 0
Neddylation R-HSA-8951664 7.691796e-01 0.114 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 7.699835e-01 0.114 0 0
Base Excision Repair R-HSA-73884 7.702460e-01 0.113 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.712019e-01 0.113 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.712019e-01 0.113 0 0
Energy dependent regulation of mTOR by LKB1-AMPK R-HSA-380972 7.712019e-01 0.113 0 0
Thrombin signalling through proteinase activated receptors (PARs) R-HSA-456926 7.712019e-01 0.113 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.712019e-01 0.113 0 0
Activation of BH3-only proteins R-HSA-114452 7.712019e-01 0.113 0 0
Interferon alpha/beta signaling R-HSA-909733 7.731478e-01 0.112 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 7.760368e-01 0.110 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 7.801342e-01 0.108 0 0
tRNA processing in the nucleus R-HSA-6784531 7.803714e-01 0.108 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 7.803966e-01 0.108 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 7.803966e-01 0.108 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 7.803966e-01 0.108 0 0
Trafficking of AMPA receptors R-HSA-399719 7.803966e-01 0.108 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 7.803966e-01 0.108 0 0
Cargo concentration in the ER R-HSA-5694530 7.803966e-01 0.108 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 7.869715e-01 0.104 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 7.869715e-01 0.104 0 0
Signaling by Insulin receptor R-HSA-74752 7.872591e-01 0.104 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 7.872591e-01 0.104 0 0
Signaling by Nuclear Receptors R-HSA-9006931 7.875934e-01 0.104 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 7.889667e-01 0.103 0 0
G alpha (s) signalling events R-HSA-418555 7.889667e-01 0.103 0 0
Inwardly rectifying K+ channels R-HSA-1296065 7.892224e-01 0.103 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.892224e-01 0.103 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 7.892224e-01 0.103 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 7.929226e-01 0.101 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 7.933965e-01 0.101 0 0
Ion transport by P-type ATPases R-HSA-936837 7.933965e-01 0.101 0 0
Leishmania parasite growth and survival R-HSA-9664433 7.970042e-01 0.099 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 7.970042e-01 0.099 0 0
Defective B3GALTL causes PpS R-HSA-5083635 7.976940e-01 0.098 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 7.976940e-01 0.098 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 7.976940e-01 0.098 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 7.976940e-01 0.098 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 7.976940e-01 0.098 0 0
G-protein beta:gamma signalling R-HSA-397795 7.976940e-01 0.098 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 7.976940e-01 0.098 0 0
Cellular response to hypoxia R-HSA-1234174 7.996498e-01 0.097 0 0
SARS-CoV-1 Infection R-HSA-9678108 8.048042e-01 0.094 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 8.057347e-01 0.094 0 0
Acyl chain remodelling of PC R-HSA-1482788 8.058256e-01 0.094 0 0
Effects of PIP2 hydrolysis R-HSA-114508 8.058256e-01 0.094 0 0
mRNA Splicing R-HSA-72172 8.099164e-01 0.092 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 8.112906e-01 0.091 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 8.132848e-01 0.090 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 8.132848e-01 0.090 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 8.132848e-01 0.090 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 8.136308e-01 0.090 0 0
eNOS activation R-HSA-203615 8.136308e-01 0.090 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 8.136308e-01 0.090 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 8.136308e-01 0.090 0 0
NOD1/2 Signaling Pathway R-HSA-168638 8.136308e-01 0.090 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 8.136308e-01 0.090 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 8.136308e-01 0.090 0 0
MITF-M-dependent gene expression R-HSA-9856651 8.167681e-01 0.088 0 0
G alpha (q) signalling events R-HSA-416476 8.210262e-01 0.086 0 0
Regulation of Apoptosis R-HSA-169911 8.211228e-01 0.086 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 8.211228e-01 0.086 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 8.211228e-01 0.086 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 8.211228e-01 0.086 0 0
Acyl chain remodelling of PE R-HSA-1482839 8.211228e-01 0.086 0 0
PERK regulates gene expression R-HSA-381042 8.211228e-01 0.086 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 8.211228e-01 0.086 0 0
Signaling by FGFR R-HSA-190236 8.229150e-01 0.085 0 0
Regulation of insulin secretion R-HSA-422356 8.229150e-01 0.085 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 8.230138e-01 0.085 0 0
FOXO-mediated transcription R-HSA-9614085 8.275693e-01 0.082 0 0
DNA Replication R-HSA-69306 8.282860e-01 0.082 0 0
Protein localization R-HSA-9609507 8.282860e-01 0.082 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 8.283140e-01 0.082 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 8.283140e-01 0.082 0 0
RNA Polymerase III Transcription R-HSA-74158 8.283140e-01 0.082 0 0
HS-GAG biosynthesis R-HSA-2022928 8.283140e-01 0.082 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 8.284596e-01 0.082 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 8.337541e-01 0.079 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 8.337541e-01 0.079 0 0
RNA Polymerase II Transcription R-HSA-73857 8.339284e-01 0.079 0 0
O-glycosylation of TSR domain-containing proteins R-HSA-5173214 8.352165e-01 0.078 0 0
Degradation of AXIN R-HSA-4641257 8.352165e-01 0.078 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 8.352165e-01 0.078 0 0
Collagen chain trimerization R-HSA-8948216 8.352165e-01 0.078 0 0
Metabolism of folate and pterines R-HSA-196757 8.352165e-01 0.078 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 8.365642e-01 0.078 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 8.396706e-01 0.076 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 8.418419e-01 0.075 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.418419e-01 0.075 0 0
HCMV Late Events R-HSA-9610379 8.427221e-01 0.074 0 0
Switching of origins to a post-replicative state R-HSA-69052 8.439025e-01 0.074 0 0
Ca2+ pathway R-HSA-4086398 8.439025e-01 0.074 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 8.439025e-01 0.074 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 8.439025e-01 0.074 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 8.461710e-01 0.073 0 0
Signaling by NOTCH4 R-HSA-9013694 8.487631e-01 0.071 0 0
Generic Transcription Pathway R-HSA-212436 8.496232e-01 0.071 0 0
Cardiac conduction R-HSA-5576891 8.514257e-01 0.070 0 0
Ion channel transport R-HSA-983712 8.530236e-01 0.069 0 0
Activation of HOX genes during differentiation R-HSA-5619507 8.533456e-01 0.069 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 8.533456e-01 0.069 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 8.543054e-01 0.068 0 0
Glycogen metabolism R-HSA-8982491 8.543054e-01 0.068 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 8.601644e-01 0.065 0 0
Translation of Structural Proteins R-HSA-9694635 8.625296e-01 0.064 0 0
Cell-cell junction organization R-HSA-421270 8.647138e-01 0.063 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 8.657881e-01 0.063 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 8.657881e-01 0.063 0 0
Heme biosynthesis R-HSA-189451 8.657881e-01 0.063 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 8.657881e-01 0.063 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 8.657881e-01 0.063 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 8.710595e-01 0.060 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 8.711860e-01 0.060 0 0
Depyrimidination R-HSA-73928 8.711860e-01 0.060 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 8.711860e-01 0.060 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 8.718537e-01 0.060 0 0
DNA Replication Pre-Initiation R-HSA-69002 8.721932e-01 0.059 0 0
Signaling by FGFR4 R-HSA-5654743 8.763671e-01 0.057 0 0
Defensins R-HSA-1461973 8.763671e-01 0.057 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 8.763671e-01 0.057 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 8.813401e-01 0.055 0 0
RMTs methylate histone arginines R-HSA-3214858 8.813401e-01 0.055 0 0
Surfactant metabolism R-HSA-5683826 8.813401e-01 0.055 0 0
Cobalamin (Cbl, vitamin B12) transport and metabolism R-HSA-196741 8.813401e-01 0.055 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 8.856966e-01 0.053 0 0
Nucleosome assembly R-HSA-774815 8.861134e-01 0.053 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 8.861134e-01 0.053 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 8.861134e-01 0.053 0 0
Signaling by FGFR3 R-HSA-5654741 8.861134e-01 0.053 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 8.861134e-01 0.053 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 8.861134e-01 0.053 0 0
Fanconi Anemia Pathway R-HSA-6783310 8.861134e-01 0.053 0 0
The canonical retinoid cycle in rods (twilight vision) R-HSA-2453902 8.861134e-01 0.053 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 8.861134e-01 0.053 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 8.861134e-01 0.053 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 8.886261e-01 0.051 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 8.906949e-01 0.050 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 8.906949e-01 0.050 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 8.910342e-01 0.050 0 0
Developmental Cell Lineages R-HSA-9734767 8.926476e-01 0.049 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 8.972187e-01 0.047 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 8.979126e-01 0.047 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 8.979126e-01 0.047 0 0
Intraflagellar transport R-HSA-5620924 8.993132e-01 0.046 0 0
Interferon Signaling R-HSA-913531 9.002388e-01 0.046 0 0
XBP1(S) activates chaperone genes R-HSA-381038 9.005251e-01 0.046 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 9.033645e-01 0.044 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 9.033645e-01 0.044 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 9.033645e-01 0.044 0 0
Chaperonin-mediated protein folding R-HSA-390466 9.037321e-01 0.044 0 0
Visual phototransduction R-HSA-2187338 9.055371e-01 0.043 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 9.109852e-01 0.040 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 9.145675e-01 0.039 0 0
Regulation of PTEN stability and activity R-HSA-8948751 9.180058e-01 0.037 0 0
IRE1alpha activates chaperones R-HSA-381070 9.183671e-01 0.037 0 0
Protein folding R-HSA-391251 9.210314e-01 0.036 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 9.210314e-01 0.036 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 9.213060e-01 0.036 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 9.213060e-01 0.036 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.213060e-01 0.036 0 0
FCGR activation R-HSA-2029481 9.236138e-01 0.035 0 0
Adherens junctions interactions R-HSA-418990 9.239215e-01 0.034 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 9.244735e-01 0.034 0 0
HDACs deacetylate histones R-HSA-3214815 9.244735e-01 0.034 0 0
Paracetamol ADME R-HSA-9753281 9.244735e-01 0.034 0 0
Signaling by NOTCH3 R-HSA-9012852 9.244735e-01 0.034 0 0
Translation R-HSA-72766 9.254713e-01 0.034 0 0
Mitochondrial protein degradation R-HSA-9837999 9.261165e-01 0.033 0 0
Signaling by FGFR1 R-HSA-5654736 9.275137e-01 0.033 0 0
Synthesis of PA R-HSA-1483166 9.304317e-01 0.031 0 0
Infectious disease R-HSA-5663205 9.308452e-01 0.031 0 0
Interferon gamma signaling R-HSA-877300 9.311370e-01 0.031 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 9.332324e-01 0.030 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.332324e-01 0.030 0 0
Peroxisomal protein import R-HSA-9033241 9.359205e-01 0.029 0 0
Triglyceride metabolism R-HSA-8979227 9.359205e-01 0.029 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 9.359205e-01 0.029 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 9.385006e-01 0.028 0 0
Glutathione conjugation R-HSA-156590 9.385006e-01 0.028 0 0
tRNA Aminoacylation R-HSA-379724 9.385006e-01 0.028 0 0
Selenoamino acid metabolism R-HSA-2408522 9.398162e-01 0.027 0 0
Gene expression (Transcription) R-HSA-74160 9.398580e-01 0.027 0 0
Collagen degradation R-HSA-1442490 9.409769e-01 0.026 0 0
Epigenetic regulation of gene expression R-HSA-212165 9.409885e-01 0.026 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.413171e-01 0.026 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 9.433537e-01 0.025 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 9.433537e-01 0.025 0 0
Co-inhibition by PD-1 R-HSA-389948 9.449158e-01 0.025 0 0
Regulation of endogenous retroelements R-HSA-9842860 9.454048e-01 0.024 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.478243e-01 0.023 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.489690e-01 0.023 0 0
Extracellular matrix organization R-HSA-1474244 9.500032e-01 0.022 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.519426e-01 0.021 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 9.529709e-01 0.021 0 0
PTEN Regulation R-HSA-6807070 9.538636e-01 0.021 0 0
Unfolded Protein Response (UPR) R-HSA-381119 9.538636e-01 0.021 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 9.542567e-01 0.020 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 9.542567e-01 0.020 0 0
Signaling by NOTCH R-HSA-157118 9.548167e-01 0.020 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 9.557363e-01 0.020 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 9.557363e-01 0.020 0 0
Antigen processing-Cross presentation R-HSA-1236975 9.569874e-01 0.019 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 9.592309e-01 0.018 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 9.592309e-01 0.018 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 9.592309e-01 0.018 0 0
Metabolism of cofactors R-HSA-8978934 9.608735e-01 0.017 0 0
Hedgehog 'on' state R-HSA-5632684 9.608735e-01 0.017 0 0
Metabolism of porphyrins R-HSA-189445 9.608735e-01 0.017 0 0
Retinoid metabolism and transport R-HSA-975634 9.608735e-01 0.017 0 0
Antimicrobial peptides R-HSA-6803157 9.611958e-01 0.017 0 0
FCERI mediated NF-kB activation R-HSA-2871837 9.615782e-01 0.017 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 9.624501e-01 0.017 0 0
Purine catabolism R-HSA-74259 9.624501e-01 0.017 0 0
Inositol phosphate metabolism R-HSA-1483249 9.625087e-01 0.017 0 0
G alpha (i) signalling events R-HSA-418594 9.633868e-01 0.016 0 0
HCMV Infection R-HSA-9609646 9.646786e-01 0.016 0 0
ROS and RNS production in phagocytes R-HSA-1222556 9.654154e-01 0.015 0 0
TP53 Regulates Transcription of Cell Death Genes R-HSA-5633008 9.668091e-01 0.015 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 9.694307e-01 0.013 0 0
GPCR downstream signalling R-HSA-388396 9.697569e-01 0.013 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 9.718051e-01 0.012 0 0
PPARA activates gene expression R-HSA-1989781 9.726723e-01 0.012 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 9.740697e-01 0.011 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.743316e-01 0.011 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 9.744035e-01 0.011 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 9.751151e-01 0.011 0 0
HCMV Early Events R-HSA-9609690 9.762045e-01 0.010 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 9.762045e-01 0.010 0 0
Post-translational protein modification R-HSA-597592 9.770556e-01 0.010 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 9.770815e-01 0.010 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 9.785171e-01 0.009 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 9.785171e-01 0.009 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 9.785171e-01 0.009 0 0
Cell surface interactions at the vascular wall R-HSA-202733 9.798627e-01 0.009 0 0
SLC transporter disorders R-HSA-5619102 9.812893e-01 0.008 0 0
Class C/3 (Metabotropic glutamate/pheromone receptors) R-HSA-420499 9.813449e-01 0.008 0 0
ER-Phagosome pathway R-HSA-1236974 9.820974e-01 0.008 0 0
Neurotransmitter release cycle R-HSA-112310 9.828196e-01 0.008 0 0
Downstream TCR signaling R-HSA-202424 9.828196e-01 0.008 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 9.835127e-01 0.007 0 0
tRNA processing R-HSA-72306 9.835338e-01 0.007 0 0
Assembly of the pre-replicative complex R-HSA-68867 9.854289e-01 0.006 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 9.865812e-01 0.006 0 0
Mitochondrial translation elongation R-HSA-5389840 9.876424e-01 0.005 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 9.881412e-01 0.005 0 0
Mitochondrial translation initiation R-HSA-5368286 9.886199e-01 0.005 0 0
Synthesis of bile acids and bile salts R-HSA-192105 9.890793e-01 0.005 0 0
ABC-family proteins mediated transport R-HSA-382556 9.895201e-01 0.005 0 0
Peptide ligand-binding receptors R-HSA-375276 9.901918e-01 0.004 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 9.905478e-01 0.004 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 9.907389e-01 0.004 0 0
Gastrulation R-HSA-9758941 9.917899e-01 0.004 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 9.926328e-01 0.003 0 0
Signaling by GPCR R-HSA-372790 9.926394e-01 0.003 0 0
Mitochondrial translation termination R-HSA-5419276 9.930604e-01 0.003 0 0
Bile acid and bile salt metabolism R-HSA-194068 9.933407e-01 0.003 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 9.948006e-01 0.002 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.953208e-01 0.002 0 0
Peptide hormone metabolism R-HSA-2980736 9.954059e-01 0.002 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.964135e-01 0.002 0 0
Nucleotide catabolism R-HSA-8956319 9.973136e-01 0.001 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 9.974083e-01 0.001 0 0
Sensory perception of taste R-HSA-9717189 9.976267e-01 0.001 0 0
Diseases of glycosylation R-HSA-3781865 9.977977e-01 0.001 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.981075e-01 0.001 0 0
O-linked glycosylation R-HSA-5173105 9.982227e-01 0.001 0 0
Metabolism of nucleotides R-HSA-15869 9.982320e-01 0.001 0 0
Mitochondrial translation R-HSA-5368287 9.982946e-01 0.001 0 0
Metabolism of steroids R-HSA-8957322 9.984279e-01 0.001 0 0
Transport of small molecules R-HSA-382551 9.987758e-01 0.001 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.987907e-01 0.001 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.990036e-01 0.000 0 0
Bacterial Infection Pathways R-HSA-9824439 9.993123e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.994039e-01 0.000 0 0
Metabolism of proteins R-HSA-392499 9.994840e-01 0.000 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.996065e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.996211e-01 0.000 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.997433e-01 0.000 0 0
Glycosaminoglycan metabolism R-HSA-1630316 9.998389e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999395e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.999451e-01 0.000 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 9.999578e-01 0.000 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.999771e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999818e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999819e-01 0.000 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.999996e-01 0.000 0 0
Biological oxidations R-HSA-211859 1.000000e+00 0.000 0 0
Fatty acid metabolism R-HSA-8978868 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Eukaryotic Translation Elongation R-HSA-156842 1.110223e-16 15.955 0 0
Peptide chain elongation R-HSA-156902 1.110223e-16 15.955 0 0
Ribosome-associated quality control R-HSA-9948299 1.110223e-16 15.955 0 0
HSF1 activation R-HSA-3371511 1.110223e-16 15.955 0 0
Attenuation phase R-HSA-3371568 1.110223e-16 15.955 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.110223e-16 15.955 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.110223e-16 15.955 0 0
HSF1-dependent transactivation R-HSA-3371571 1.110223e-16 15.955 0 0
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 1.110223e-16 15.955 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.110223e-16 15.955 0 0
Axon guidance R-HSA-422475 1.110223e-16 15.955 0 0
Nervous system development R-HSA-9675108 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Metabolism of RNA R-HSA-8953854 3.330669e-16 15.477 0 0
Influenza Infection R-HSA-168255 3.330669e-16 15.477 0 0
Cytokine Signaling in Immune system R-HSA-1280215 3.330669e-16 15.477 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 5.551115e-16 15.256 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 5.551115e-16 15.256 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 5.551115e-16 15.256 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.110223e-15 14.955 0 0
Signaling by ROBO receptors R-HSA-376176 2.220446e-15 14.654 0 0
SARS-CoV-1-host interactions R-HSA-9692914 2.664535e-15 14.574 0 0
Aggrephagy R-HSA-9646399 2.997602e-15 14.523 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 3.330669e-15 14.477 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 3.885781e-15 14.411 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 6.439294e-15 14.191 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.054712e-14 13.977 0 0
Interferon Signaling R-HSA-913531 1.199041e-14 13.921 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 2.065015e-14 13.685 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 3.053113e-14 13.515 0 0
M Phase R-HSA-68886 4.152234e-14 13.382 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 4.340972e-14 13.362 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 6.128431e-14 13.213 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 6.128431e-14 13.213 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 7.016610e-14 13.154 0 0
PKR-mediated signaling R-HSA-9833482 7.627232e-14 13.118 0 0
Eukaryotic Translation Termination R-HSA-72764 7.671641e-14 13.115 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.115774e-13 12.952 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 1.563194e-13 12.806 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.201572e-13 12.657 0 0
Selenocysteine synthesis R-HSA-2408557 2.624567e-13 12.581 0 0
Viral mRNA Translation R-HSA-192823 3.889111e-13 12.410 0 0
Transport of connexons to the plasma membrane R-HSA-190872 3.969047e-13 12.401 0 0
Translation initiation complex formation R-HSA-72649 4.627410e-13 12.335 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 9.227064e-13 12.035 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 1.003309e-12 11.999 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.393552e-12 11.856 0 0
Viral Infection Pathways R-HSA-9824446 3.817613e-12 11.418 0 0
Selective autophagy R-HSA-9663891 4.117151e-12 11.385 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 7.236323e-12 11.140 0 0
Translation R-HSA-72766 7.992829e-12 11.097 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 8.532730e-12 11.069 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 9.683143e-12 11.014 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.877443e-11 10.726 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.991973e-11 10.701 0 0
Gap junction trafficking R-HSA-190828 2.119804e-11 10.674 0 0
Post NMDA receptor activation events R-HSA-438064 2.289835e-11 10.640 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 3.141665e-11 10.503 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 3.766432e-11 10.424 0 0
Cell-Cell communication R-HSA-1500931 4.237344e-11 10.373 0 0
Cell Cycle, Mitotic R-HSA-69278 4.634382e-11 10.334 0 0
Recycling pathway of L1 R-HSA-437239 4.976242e-11 10.303 0 0
Cell Cycle R-HSA-1640170 6.385559e-11 10.195 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 6.557077e-11 10.183 0 0
SARS-CoV-1 Infection R-HSA-9678108 8.452428e-11 10.073 0 0
Gap junction trafficking and regulation R-HSA-157858 8.543011e-11 10.068 0 0
Selenoamino acid metabolism R-HSA-2408522 8.827827e-11 10.054 0 0
SARS-CoV-2-host interactions R-HSA-9705683 1.073215e-10 9.969 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.132688e-10 9.946 0 0
Mitotic Anaphase R-HSA-68882 1.237117e-10 9.908 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 1.375320e-10 9.862 0 0
Cell junction organization R-HSA-446728 2.418140e-10 9.617 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 3.019397e-10 9.520 0 0
G2/M Transition R-HSA-69275 3.053759e-10 9.515 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.820397e-10 9.418 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 3.792580e-10 9.421 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 4.674444e-10 9.330 0 0
Autophagy R-HSA-9612973 6.925520e-10 9.160 0 0
Gap junction assembly R-HSA-190861 7.148677e-10 9.146 0 0
Cellular response to starvation R-HSA-9711097 8.815639e-10 9.055 0 0
Signaling by ERBB2 R-HSA-1227986 1.188432e-09 8.925 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.631900e-09 8.787 0 0
Separation of Sister Chromatids R-HSA-2467813 1.781186e-09 8.749 0 0
Infectious disease R-HSA-5663205 2.006127e-09 8.698 0 0
Macroautophagy R-HSA-1632852 2.021139e-09 8.694 0 0
rRNA processing R-HSA-72312 2.374912e-09 8.624 0 0
Regulation of CDH1 Function R-HSA-9764561 4.512416e-09 8.346 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 4.821333e-09 8.317 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.473113e-09 8.189 0 0
Developmental Biology R-HSA-1266738 6.987085e-09 8.156 0 0
Platelet activation, signaling and aggregation R-HSA-76002 7.433111e-09 8.129 0 0
Immune System R-HSA-168256 1.008116e-08 7.996 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 1.262095e-08 7.899 0 0
Signaling by RAS mutants R-HSA-6802949 2.197215e-08 7.658 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.197215e-08 7.658 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.197215e-08 7.658 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.197215e-08 7.658 0 0
Apoptotic execution phase R-HSA-75153 2.197215e-08 7.658 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 2.215112e-08 7.655 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 2.215112e-08 7.655 0 0
Apoptosis R-HSA-109581 2.511615e-08 7.600 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 2.748361e-08 7.561 0 0
L1CAM interactions R-HSA-373760 2.781773e-08 7.556 0 0
Chaperonin-mediated protein folding R-HSA-390466 3.088709e-08 7.510 0 0
HCMV Early Events R-HSA-9609690 5.281448e-08 7.277 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 5.197463e-08 7.284 0 0
Signaling by RAF1 mutants R-HSA-9656223 5.356900e-08 7.271 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 5.368076e-08 7.270 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 6.133604e-08 7.212 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 6.721659e-08 7.173 0 0
Protein folding R-HSA-391251 7.529452e-08 7.123 0 0
Hemostasis R-HSA-109582 9.410536e-08 7.026 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.058569e-07 6.975 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.162817e-07 6.934 0 0
Programmed Cell Death R-HSA-5357801 1.287850e-07 6.890 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.412279e-07 6.850 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 1.421231e-07 6.847 0 0
Interleukin-12 signaling R-HSA-9020591 1.451907e-07 6.838 0 0
Mitotic Prometaphase R-HSA-68877 1.459310e-07 6.836 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.748868e-07 6.757 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.936828e-07 6.713 0 0
Mitotic Prophase R-HSA-68875 2.052545e-07 6.688 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 2.283517e-07 6.641 0 0
Hedgehog 'off' state R-HSA-5610787 2.555318e-07 6.593 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.565175e-07 6.591 0 0
Host Interactions of HIV factors R-HSA-162909 3.233765e-07 6.490 0 0
Kinesins R-HSA-983189 3.487890e-07 6.457 0 0
MAPK family signaling cascades R-HSA-5683057 4.358832e-07 6.361 0 0
mRNA Splicing - Major Pathway R-HSA-72163 5.576889e-07 6.254 0 0
Cell-extracellular matrix interactions R-HSA-446353 6.921794e-07 6.160 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 7.987384e-07 6.098 0 0
Interleukin-12 family signaling R-HSA-447115 8.256927e-07 6.083 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 9.956083e-07 6.002 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.123231e-06 5.950 0 0
Glycolysis R-HSA-70171 1.177526e-06 5.929 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 1.220410e-06 5.913 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.246243e-06 5.904 0 0
HCMV Infection R-HSA-9609646 1.309916e-06 5.883 0 0
mRNA Splicing R-HSA-72172 1.357660e-06 5.867 0 0
Cell-cell junction organization R-HSA-421270 1.404768e-06 5.852 0 0
EPH-Ephrin signaling R-HSA-2682334 1.785128e-06 5.748 0 0
Signaling by Interleukins R-HSA-449147 1.798489e-06 5.745 0 0
Platelet degranulation R-HSA-114608 2.010762e-06 5.697 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.049577e-06 5.688 0 0
MAP2K and MAPK activation R-HSA-5674135 2.764406e-06 5.558 0 0
Regulation of signaling by CBL R-HSA-912631 3.827442e-06 5.417 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.845211e-06 5.415 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.845211e-06 5.415 0 0
Disease R-HSA-1643685 3.884903e-06 5.411 0 0
Cilium Assembly R-HSA-5617833 4.470396e-06 5.350 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 4.517307e-06 5.345 0 0
Organelle biogenesis and maintenance R-HSA-1852241 4.846989e-06 5.315 0 0
SARS-CoV Infections R-HSA-9679506 5.160725e-06 5.287 0 0
Transmission across Chemical Synapses R-HSA-112315 5.753516e-06 5.240 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 6.383407e-06 5.195 0 0
Signaling by Hedgehog R-HSA-5358351 6.887478e-06 5.162 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 7.012026e-06 5.154 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 8.151086e-06 5.089 0 0
Intraflagellar transport R-HSA-5620924 9.565832e-06 5.019 0 0
Signal Transduction R-HSA-162582 9.968617e-06 5.001 1 0
Glucose metabolism R-HSA-70326 1.013223e-05 4.994 0 0
TICAM1,TRAF6-dependent induction of TAK1 complex R-HSA-9014325 1.037112e-05 4.984 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.088815e-05 4.963 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 1.288283e-05 4.890 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.656779e-05 4.781 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.671277e-05 4.777 0 0
Signaling by PTK6 R-HSA-8848021 1.671277e-05 4.777 0 0
MHC class II antigen presentation R-HSA-2132295 1.778059e-05 4.750 0 0
Cellular Senescence R-HSA-2559583 2.115959e-05 4.674 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.739944e-05 4.562 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.878945e-05 4.541 0 0
Adherens junctions interactions R-HSA-418990 3.364656e-05 4.473 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 3.774745e-05 4.423 0 0
Regulation of PTEN localization R-HSA-8948747 3.938041e-05 4.405 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 4.111651e-05 4.386 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 5.220165e-05 4.282 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 5.511373e-05 4.259 0 0
COPI-mediated anterograde transport R-HSA-6807878 5.511373e-05 4.259 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 6.155398e-05 4.211 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 5.885921e-05 4.230 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 5.885921e-05 4.230 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 6.709396e-05 4.173 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 6.268725e-05 4.203 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 7.430416e-05 4.129 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 8.094108e-05 4.092 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 8.409460e-05 4.075 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 8.409460e-05 4.075 0 0
IRAK2 mediated activation of TAK1 complex R-HSA-937042 9.230448e-05 4.035 0 0
G2/M Checkpoints R-HSA-69481 9.466701e-05 4.024 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 9.707822e-05 4.013 0 0
Negative regulation of MAPK pathway R-HSA-5675221 1.009088e-04 3.996 0 0
Neutrophil degranulation R-HSA-6798695 1.081293e-04 3.966 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.106590e-04 3.956 0 0
Josephin domain DUBs R-HSA-5689877 1.336807e-04 3.874 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 1.336807e-04 3.874 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 1.415000e-04 3.849 0 0
Adaptive Immune System R-HSA-1280218 1.415890e-04 3.849 0 0
FLT3 signaling by CBL mutants R-HSA-9706377 1.438082e-04 3.842 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 1.442095e-04 3.841 0 0
HIV Infection R-HSA-162906 1.563366e-04 3.806 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.879485e-04 3.726 0 0
Nuclear import of Rev protein R-HSA-180746 1.622011e-04 3.790 0 0
Signaling by Hippo R-HSA-2028269 1.849029e-04 3.733 1 1
Alpha-protein kinase 1 signaling pathway R-HSA-9645460 1.879485e-04 3.726 0 0
Membrane Trafficking R-HSA-199991 1.632635e-04 3.787 0 0
Gene Silencing by RNA R-HSA-211000 1.647086e-04 3.783 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 1.890920e-04 3.723 0 0
Regulation of Apoptosis R-HSA-169911 1.905898e-04 3.720 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 2.084112e-04 3.681 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.089080e-04 3.680 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 2.229366e-04 3.652 0 0
Ephrin signaling R-HSA-3928664 2.341604e-04 3.630 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.357767e-04 3.627 0 0
Maturation of protein E R-HSA-9683683 2.383764e-04 3.623 0 0
Maturation of protein E R-HSA-9694493 2.383764e-04 3.623 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 2.575809e-04 3.589 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 2.575809e-04 3.589 0 0
Ovarian tumor domain proteases R-HSA-5689896 2.596510e-04 3.586 0 0
Signaling by VEGF R-HSA-194138 2.631085e-04 3.580 0 0
Gluconeogenesis R-HSA-70263 2.686124e-04 3.571 0 0
Translesion Synthesis by POLH R-HSA-110320 2.931985e-04 3.533 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 3.027658e-04 3.519 0 0
Degradation of CDH1 R-HSA-9766229 3.051477e-04 3.515 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 3.051477e-04 3.515 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 3.051477e-04 3.515 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 3.452450e-04 3.462 0 0
VLDLR internalisation and degradation R-HSA-8866427 3.452450e-04 3.462 0 0
p75NTR recruits signalling complexes R-HSA-209543 3.452450e-04 3.462 0 0
Regulation of RAS by GAPs R-HSA-5658442 3.456974e-04 3.461 0 0
Stabilization of p53 R-HSA-69541 3.479522e-04 3.458 0 0
Semaphorin interactions R-HSA-373755 3.522451e-04 3.453 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.563972e-04 3.448 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 3.563972e-04 3.448 0 0
Clathrin-mediated endocytosis R-HSA-8856828 3.775966e-04 3.423 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 3.905940e-04 3.408 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 4.004917e-04 3.397 0 0
PCP/CE pathway R-HSA-4086400 4.062072e-04 3.391 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.948446e-04 3.306 0 0
EGFR downregulation R-HSA-182971 4.942461e-04 3.306 0 0
activated TAK1 mediates p38 MAPK activation R-HSA-450302 5.424711e-04 3.266 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 4.593045e-04 3.338 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 4.942461e-04 3.306 0 0
Metabolism of proteins R-HSA-392499 4.756209e-04 3.323 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 5.862272e-04 3.232 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 5.979578e-04 3.223 0 0
G alpha (z) signalling events R-HSA-418597 6.209122e-04 3.207 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 6.509000e-04 3.186 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 6.545271e-04 3.184 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 6.715642e-04 3.173 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 6.789714e-04 3.168 0 0
Neuronal System R-HSA-112316 6.893378e-04 3.162 0 0
TCR signaling R-HSA-202403 6.939120e-04 3.159 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 7.211296e-04 3.142 0 0
TICAM1, RIP1-mediated IKK complex recruitment R-HSA-168927 7.457225e-04 3.127 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 7.457225e-04 3.127 0 0
Protein methylation R-HSA-8876725 7.457225e-04 3.127 0 0
Spry regulation of FGF signaling R-HSA-1295596 7.457225e-04 3.127 0 0
p75NTR signals via NF-kB R-HSA-193639 7.457225e-04 3.127 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 7.686047e-04 3.114 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 7.773543e-04 3.109 0 0
Vpu mediated degradation of CD4 R-HSA-180534 7.773543e-04 3.109 0 0
Myoclonic epilepsy of Lafora R-HSA-3785653 7.818120e-04 3.107 0 0
Modulation by Mtb of host immune system R-HSA-9637628 7.818120e-04 3.107 0 0
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 R-HSA-8849469 7.818120e-04 3.107 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 8.019589e-04 3.096 0 0
RAF activation R-HSA-5673000 8.958963e-04 3.048 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.028242e-03 2.988 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 8.958963e-04 3.048 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 1.028242e-03 2.988 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 1.028242e-03 2.988 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 8.675130e-04 3.062 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 9.594901e-04 3.018 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 8.958963e-04 3.048 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 8.958963e-04 3.048 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 9.763793e-04 3.010 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 9.317653e-04 3.031 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 8.675130e-04 3.062 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 8.675130e-04 3.062 0 0
Signaling by ERBB4 R-HSA-1236394 1.046580e-03 2.980 0 0
Signaling by NOTCH4 R-HSA-9013694 1.046580e-03 2.980 0 0
Long-term potentiation R-HSA-9620244 1.100433e-03 2.958 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 1.159187e-03 2.936 0 0
ER-Phagosome pathway R-HSA-1236974 1.161968e-03 2.935 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.175485e-03 2.930 0 0
Downstream TCR signaling R-HSA-202424 1.258228e-03 2.900 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 1.284257e-03 2.891 0 0
Degradation of DVL R-HSA-4641258 1.338758e-03 2.873 0 0
Degradation of AXIN R-HSA-4641257 1.338758e-03 2.873 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 1.338758e-03 2.873 0 0
Innate Immune System R-HSA-168249 1.350934e-03 2.869 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.353730e-03 2.868 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 1.413760e-03 2.850 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 1.413760e-03 2.850 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 1.413760e-03 2.850 0 0
Pexophagy R-HSA-9664873 1.440353e-03 2.842 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.460779e-03 2.835 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 1.507074e-03 2.822 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 1.519234e-03 2.818 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 1.695832e-03 2.771 0 0
Hedgehog ligand biogenesis R-HSA-5358346 1.695832e-03 2.771 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.711140e-03 2.767 0 0
Cell Cycle Checkpoints R-HSA-69620 1.713261e-03 2.766 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.715079e-03 2.766 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 1.718121e-03 2.765 0 0
RAS processing R-HSA-9648002 1.718121e-03 2.765 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 1.718121e-03 2.765 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.718121e-03 2.765 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.718121e-03 2.765 0 0
Regulation of TP53 Activity through Methylation R-HSA-6804760 1.721840e-03 2.764 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.731935e-03 2.761 0 0
Signaling by ALK in cancer R-HSA-9700206 1.731935e-03 2.761 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.866438e-03 2.729 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 1.880256e-03 2.726 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 1.880256e-03 2.726 0 0
Orc1 removal from chromatin R-HSA-68949 1.880256e-03 2.726 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.880256e-03 2.726 0 0
PECAM1 interactions R-HSA-210990 1.882839e-03 2.725 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.068123e-03 2.684 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.068123e-03 2.684 0 0
Late endosomal microautophagy R-HSA-9615710 2.019093e-03 2.695 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 2.019093e-03 2.695 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 2.319672e-03 2.635 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 1.936662e-03 2.713 0 0
Ub-specific processing proteases R-HSA-5689880 2.285786e-03 2.641 0 0
Regulation of PTEN stability and activity R-HSA-8948751 2.080140e-03 2.682 0 0
Nephrin family interactions R-HSA-373753 2.462631e-03 2.609 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 2.080140e-03 2.682 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 2.529843e-03 2.597 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 2.296368e-03 2.639 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 2.403969e-03 2.619 0 0
HIV Life Cycle R-HSA-162587 2.379897e-03 2.623 0 0
Degradation of CRY and PER proteins R-HSA-9932298 2.437845e-03 2.613 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 2.437845e-03 2.613 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.899847e-03 2.721 0 0
Amyloid fiber formation R-HSA-977225 1.899847e-03 2.721 0 0
ATF6 (ATF6-alpha) activates chaperone genes R-HSA-381183 2.411503e-03 2.618 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 2.437845e-03 2.613 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 2.437845e-03 2.613 0 0
Smooth Muscle Contraction R-HSA-445355 2.080140e-03 2.682 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 2.325478e-03 2.633 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 1.936662e-03 2.713 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 1.936662e-03 2.713 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 2.176134e-03 2.662 0 0
DNA Replication Pre-Initiation R-HSA-69002 1.983403e-03 2.703 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.185046e-03 2.661 0 0
NF-kB is activated and signals survival R-HSA-209560 2.411503e-03 2.618 0 0
G-protein mediated events R-HSA-112040 2.040721e-03 2.690 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 2.176134e-03 2.662 0 0
FLT3 Signaling R-HSA-9607240 2.176134e-03 2.662 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 2.652745e-03 2.576 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 2.652745e-03 2.576 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 2.652745e-03 2.576 0 0
Late Phase of HIV Life Cycle R-HSA-162599 2.729932e-03 2.564 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 2.729932e-03 2.564 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 2.781487e-03 2.556 0 0
Signaling by EGFR R-HSA-177929 2.781487e-03 2.556 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 2.781487e-03 2.556 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 2.871797e-03 2.542 0 0
Regulation of mitotic cell cycle R-HSA-453276 2.871797e-03 2.542 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 2.871797e-03 2.542 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 2.909094e-03 2.536 0 0
Prevention of phagosomal-lysosomal fusion R-HSA-9636383 2.909094e-03 2.536 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 3.033351e-03 2.518 0 0
Response of Mtb to phagocytosis R-HSA-9637690 3.033351e-03 2.518 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 3.034175e-03 2.518 0 0
Signaling by NOTCH1 HD Domain Mutants in Cancer R-HSA-2691230 3.034175e-03 2.518 0 0
Constitutive Signaling by NOTCH1 HD Domain Mutants R-HSA-2691232 3.034175e-03 2.518 0 0
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation R-HSA-975144 3.034175e-03 2.518 0 0
IRAK1 recruits IKK complex R-HSA-937039 3.034175e-03 2.518 0 0
Interferon alpha/beta signaling R-HSA-909733 3.305986e-03 2.481 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 3.329109e-03 2.478 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.369896e-03 2.472 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 3.377152e-03 2.471 0 0
Gap-filling DNA repair synthesis and ligation in GG-NER R-HSA-5696397 3.411254e-03 2.467 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.411254e-03 2.467 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 3.411254e-03 2.467 0 0
Assembly Of The HIV Virion R-HSA-175474 3.411254e-03 2.467 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 3.424918e-03 2.465 0 0
Regulation of necroptotic cell death R-HSA-5675482 3.424918e-03 2.465 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 3.456275e-03 2.461 0 0
Diseases of programmed cell death R-HSA-9645723 3.484990e-03 2.458 0 0
ER to Golgi Anterograde Transport R-HSA-199977 3.571140e-03 2.447 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 3.654963e-03 2.437 0 0
Vesicle-mediated transport R-HSA-5653656 3.678007e-03 2.434 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 3.734171e-03 2.428 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 3.734171e-03 2.428 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 3.734171e-03 2.428 0 0
Membrane binding and targetting of GAG proteins R-HSA-174490 3.758464e-03 2.425 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 3.758464e-03 2.425 0 0
ATF6 (ATF6-alpha) activates chaperones R-HSA-381033 3.758464e-03 2.425 0 0
Striated Muscle Contraction R-HSA-390522 3.868356e-03 2.412 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 3.868356e-03 2.412 0 0
Centrosome maturation R-HSA-380287 3.949922e-03 2.403 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 3.972850e-03 2.401 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.011495e-03 2.397 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 4.127605e-03 2.384 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.127605e-03 2.384 0 0
UCH proteinases R-HSA-5689603 4.263427e-03 2.370 0 0
Intracellular signaling by second messengers R-HSA-9006925 4.376172e-03 2.359 0 0
Nucleotide Excision Repair R-HSA-5696398 4.443909e-03 2.352 0 0
Manipulation of host energy metabolism R-HSA-9636667 5.571191e-03 2.254 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 4.614612e-03 2.336 0 0
Disinhibition of SNARE formation R-HSA-114516 6.162819e-03 2.210 0 0
Adenylate cyclase inhibitory pathway R-HSA-170670 5.540975e-03 2.256 0 0
Translesion synthesis by POLI R-HSA-5656121 6.612947e-03 2.180 0 0
Tight junction interactions R-HSA-420029 6.051288e-03 2.218 0 0
Translesion synthesis by REV1 R-HSA-110312 5.540975e-03 2.256 0 0
PTEN Regulation R-HSA-6807070 5.643841e-03 2.248 0 0
Neurodegenerative Diseases R-HSA-8863678 5.289204e-03 2.277 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 5.289204e-03 2.277 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.551639e-03 2.342 0 0
Protein localization R-HSA-9609507 4.848009e-03 2.314 0 0
Synthesis And Processing Of GAG, GAGPOL Polyproteins R-HSA-174495 4.591716e-03 2.338 0 0
Regulation of KIT signaling R-HSA-1433559 4.591716e-03 2.338 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 6.075782e-03 2.216 0 0
Cellular response to hypoxia R-HSA-1234174 6.025022e-03 2.220 0 0
NRIF signals cell death from the nucleus R-HSA-205043 4.591716e-03 2.338 0 0
Nef and signal transduction R-HSA-164944 4.614612e-03 2.336 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 6.162819e-03 2.210 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 6.747102e-03 2.171 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 5.540975e-03 2.256 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 5.565472e-03 2.254 0 0
Antigen processing-Cross presentation R-HSA-1236975 5.335673e-03 2.273 0 0
TAK1-dependent IKK and NF-kappa-B activation R-HSA-445989 4.551639e-03 2.342 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 4.591716e-03 2.338 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 6.572324e-03 2.182 0 0
Muscle contraction R-HSA-397014 6.031907e-03 2.220 0 0
Regulation of NF-kappa B signaling R-HSA-9758274 6.612947e-03 2.180 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 5.089816e-03 2.293 0 0
Regulation of BACH1 activity R-HSA-9708530 6.612947e-03 2.180 0 0
Negative regulation of FLT3 R-HSA-9706369 6.612947e-03 2.180 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 6.774774e-03 2.169 0 0
Suppression of phagosomal maturation R-HSA-9637687 6.887436e-03 2.162 0 0
Deubiquitination R-HSA-5688426 6.994637e-03 2.155 0 0
DNA Double Strand Break Response R-HSA-5693606 7.030007e-03 2.153 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 7.182152e-03 2.144 0 0
mRNA 3'-end processing R-HSA-72187 7.182152e-03 2.144 0 0
ESR-mediated signaling R-HSA-8939211 7.474075e-03 2.126 0 0
Regulated Necrosis R-HSA-5218859 7.577583e-03 2.120 0 0
Signaling by WNT R-HSA-195721 7.692547e-03 2.114 0 0
Metabolism of amino acids and derivatives R-HSA-71291 7.698101e-03 2.114 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 7.801152e-03 2.108 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 7.801152e-03 2.108 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 7.801152e-03 2.108 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 7.801152e-03 2.108 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 7.813977e-03 2.107 0 0
Translesion synthesis by POLK R-HSA-5655862 7.813977e-03 2.107 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 7.813977e-03 2.107 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 7.813977e-03 2.107 0 0
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling R-HSA-975110 7.813977e-03 2.107 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 7.820682e-03 2.107 0 0
Type I hemidesmosome assembly R-HSA-446107 7.986407e-03 2.098 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 7.986407e-03 2.098 0 0
Formation of annular gap junctions R-HSA-196025 7.986407e-03 2.098 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 8.248472e-03 2.084 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 8.248472e-03 2.084 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 8.768279e-03 2.057 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 8.770062e-03 2.057 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 8.795857e-03 2.056 0 0
Negative regulation of FGFR3 signaling R-HSA-5654732 8.795857e-03 2.056 0 0
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template R-HSA-110313 9.082846e-03 2.042 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 9.082846e-03 2.042 0 0
Interleukin-1 signaling R-HSA-9020702 9.135608e-03 2.039 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 9.150026e-03 2.039 0 0
Regulation of FZD by ubiquitination R-HSA-4641263 9.150026e-03 2.039 0 0
Glycogen storage diseases R-HSA-3229121 9.150026e-03 2.039 0 0
Signaling by NOTCH3 R-HSA-9012852 9.222026e-03 2.035 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 9.669420e-03 2.015 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 9.669420e-03 2.015 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 9.669420e-03 2.015 0 0
TGFBR1 LBD Mutants in Cancer R-HSA-3656535 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 9.669420e-03 2.015 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 9.669420e-03 2.015 0 0
Negative regulation of FGFR4 signaling R-HSA-5654733 9.874874e-03 2.005 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.009355e-02 1.996 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 1.009355e-02 1.996 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 1.009355e-02 1.996 0 0
Gap junction degradation R-HSA-190873 1.009563e-02 1.996 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.009563e-02 1.996 0 0
Homology Directed Repair R-HSA-5693538 1.039596e-02 1.983 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 1.062665e-02 1.974 0 0
Switching of origins to a post-replicative state R-HSA-69052 1.080934e-02 1.966 0 0
Opioid Signalling R-HSA-111885 1.082696e-02 1.965 0 0
DNA Double-Strand Break Repair R-HSA-5693532 1.149734e-02 1.939 0 0
DNA Replication R-HSA-69306 1.149734e-02 1.939 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.156199e-02 1.937 0 0
Dual incision in TC-NER R-HSA-6782135 1.165677e-02 1.933 0 0
Signaling by FGFR4 R-HSA-5654743 1.194608e-02 1.923 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.195808e-02 1.922 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 1.207992e-02 1.918 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.210402e-02 1.917 0 0
Trafficking of AMPA receptors R-HSA-399719 1.229859e-02 1.910 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 1.229859e-02 1.910 0 0
Budding and maturation of HIV virion R-HSA-162588 1.229859e-02 1.910 0 0
Protein ubiquitination R-HSA-8852135 1.235257e-02 1.908 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 1.235257e-02 1.908 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.249853e-02 1.903 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 1.249853e-02 1.903 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.249853e-02 1.903 0 0
Metabolism of non-coding RNA R-HSA-194441 1.256287e-02 1.901 0 0
snRNP Assembly R-HSA-191859 1.256287e-02 1.901 0 0
G1 Phase R-HSA-69236 1.302735e-02 1.885 0 0
Cyclin D associated events in G1 R-HSA-69231 1.302735e-02 1.885 0 0
Unfolded Protein Response (UPR) R-HSA-381119 1.363343e-02 1.865 0 0
Downregulation of SMAD2/3:SMAD4 transcriptional activity R-HSA-2173795 1.364938e-02 1.865 0 0
Negative regulation of MET activity R-HSA-6807004 1.402178e-02 1.853 0 0
Glycogen synthesis R-HSA-3322077 1.402178e-02 1.853 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.416054e-02 1.849 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 1.416054e-02 1.849 0 0
DAG and IP3 signaling R-HSA-1489509 1.417537e-02 1.848 0 0
Signaling by FGFR3 R-HSA-5654741 1.417537e-02 1.848 0 0
Viral Messenger RNA Synthesis R-HSA-168325 1.452533e-02 1.838 0 0
MAP kinase activation R-HSA-450294 1.452533e-02 1.838 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.452533e-02 1.838 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 1.452533e-02 1.838 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 1.491034e-02 1.827 0 0
ABC transporter disorders R-HSA-5619084 1.496237e-02 1.825 0 0
Negative regulation of FGFR1 signaling R-HSA-5654726 1.509661e-02 1.821 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.509661e-02 1.821 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 1.539202e-02 1.813 0 0
tRNA processing in the nucleus R-HSA-6784531 1.558444e-02 1.807 0 0
MyD88-independent TLR4 cascade R-HSA-166166 1.568934e-02 1.804 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 1.568934e-02 1.804 0 0
ADP signalling through P2Y purinoceptor 12 R-HSA-392170 1.594928e-02 1.797 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 1.594928e-02 1.797 0 0
NOTCH2 Activation and Transmission of Signal to the Nucleus R-HSA-2979096 1.594928e-02 1.797 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 1.594928e-02 1.797 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 1.648226e-02 1.783 0 0
Co-inhibition by PD-1 R-HSA-389948 1.651579e-02 1.782 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.664300e-02 1.779 0 0
Signaling by NOTCH R-HSA-157118 1.681131e-02 1.774 0 0
Signaling by FGFR2 R-HSA-5654738 1.691095e-02 1.772 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 1.803535e-02 1.744 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 1.820798e-02 1.740 0 0
Mitophagy R-HSA-5205647 1.829110e-02 1.738 0 0
NOD1/2 Signaling Pathway R-HSA-168638 1.829110e-02 1.738 0 0
Negative regulation of FGFR2 signaling R-HSA-5654727 1.829110e-02 1.738 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.911019e-02 1.719 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 1.934954e-02 1.713 0 0
DNA Damage Bypass R-HSA-73893 1.947207e-02 1.711 0 0
mTORC1-mediated signalling R-HSA-166208 2.028341e-02 1.693 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 2.028341e-02 1.693 0 0
Signaling by KIT in disease R-HSA-9669938 2.028341e-02 1.693 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 2.038095e-02 1.691 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 2.038095e-02 1.691 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 2.038095e-02 1.691 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 2.074098e-02 1.683 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 2.074098e-02 1.683 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 2.074098e-02 1.683 0 0
MTF1 activates gene expression R-HSA-5660489 2.074098e-02 1.683 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 2.101233e-02 1.678 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 2.134499e-02 1.671 0 0
PRC2 methylates histones and DNA R-HSA-212300 2.190192e-02 1.660 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 2.190192e-02 1.660 0 0
Calmodulin induced events R-HSA-111933 2.190192e-02 1.660 0 0
CaM pathway R-HSA-111997 2.190192e-02 1.660 0 0
FLT3 signaling in disease R-HSA-9682385 2.190192e-02 1.660 0 0
Meiotic recombination R-HSA-912446 2.256761e-02 1.647 0 0
Meiosis R-HSA-1500620 2.257093e-02 1.646 0 0
Syndecan interactions R-HSA-3000170 2.269643e-02 1.644 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 2.311194e-02 1.636 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 2.384568e-02 1.623 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 2.386898e-02 1.622 0 0
DEx/H-box helicases activate type I IFN and inflammatory cytokines production R-HSA-3134963 2.756731e-02 1.560 0 0
Loss of Function of TGFBR1 in Cancer R-HSA-3656534 2.756731e-02 1.560 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 4.346349e-02 1.362 0 0
RAS signaling downstream of NF1 loss-of-function variants R-HSA-6802953 4.346349e-02 1.362 0 0
CD28 dependent Vav1 pathway R-HSA-389359 2.513966e-02 1.600 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 3.782977e-02 1.422 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 4.266048e-02 1.370 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 4.778414e-02 1.321 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 4.778414e-02 1.321 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 4.778414e-02 1.321 0 0
DNA methylation R-HSA-5334118 4.075224e-02 1.390 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 4.075224e-02 1.390 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 3.285799e-02 1.483 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 2.423279e-02 1.616 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 4.054662e-02 1.392 0 0
FCERI mediated NF-kB activation R-HSA-2871837 3.842263e-02 1.415 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 4.778414e-02 1.321 0 0
Metalloprotease DUBs R-HSA-5689901 3.094865e-02 1.509 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 3.308204e-02 1.480 0 0
Toxicity of botulinum toxin type G (botG) R-HSA-5250989 2.756731e-02 1.560 0 0
Mitochondrial protein import R-HSA-1268020 4.549476e-02 1.342 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 3.043943e-02 1.517 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.768413e-02 1.558 0 0
RNA Polymerase I Transcription R-HSA-73864 4.064271e-02 1.391 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 3.660131e-02 1.437 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 3.516273e-02 1.454 0 0
Termination of translesion DNA synthesis R-HSA-5656169 4.075224e-02 1.390 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 3.285799e-02 1.483 0 0
Fanconi Anemia Pathway R-HSA-6783310 4.671645e-02 1.331 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 4.496407e-02 1.347 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 3.782977e-02 1.422 0 0
Signaling by TGF-beta Receptor Complex in Cancer R-HSA-3304351 4.346349e-02 1.362 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 3.285799e-02 1.483 0 0
Signaling by SCF-KIT R-HSA-1433557 4.081644e-02 1.389 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 4.433732e-02 1.353 0 0
Developmental Cell Lineages R-HSA-9734767 3.372465e-02 1.472 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.416257e-02 1.355 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 2.513966e-02 1.600 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.513966e-02 1.600 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.527697e-02 1.597 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 3.404281e-02 1.468 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 2.636590e-02 1.579 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 2.636590e-02 1.579 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 3.001139e-02 1.523 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 4.266048e-02 1.370 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 3.001139e-02 1.523 0 0
DNA Repair R-HSA-73894 4.248278e-02 1.372 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.802714e-02 1.552 0 0
RAB geranylgeranylation R-HSA-8873719 4.054662e-02 1.392 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 2.513966e-02 1.600 0 0
G1/S Transition R-HSA-69206 3.540791e-02 1.451 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 4.064271e-02 1.391 0 0
Defective pyroptosis R-HSA-9710421 4.081644e-02 1.389 0 0
TNF signaling R-HSA-75893 3.170903e-02 1.499 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 4.130673e-02 1.384 0 0
Interleukin-17 signaling R-HSA-448424 2.609718e-02 1.583 0 0
Reproduction R-HSA-1474165 4.471384e-02 1.350 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 2.741548e-02 1.562 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 3.170903e-02 1.499 0 0
Activated NOTCH1 Transmits Signal to the Nucleus R-HSA-2122948 3.094865e-02 1.509 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 3.595353e-02 1.444 0 0
TCF dependent signaling in response to WNT R-HSA-201681 3.731333e-02 1.428 0 0
ER Quality Control Compartment (ERQC) R-HSA-901032 3.404281e-02 1.468 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 4.549476e-02 1.342 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 2.517011e-02 1.599 0 0
Ca-dependent events R-HSA-111996 3.804549e-02 1.420 0 0
Interleukin-1 family signaling R-HSA-446652 2.451202e-02 1.611 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 4.726126e-02 1.325 0 0
Plasma lipoprotein clearance R-HSA-8964043 2.813606e-02 1.551 0 0
Signaling by FGFR1 R-HSA-5654736 3.170903e-02 1.499 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 3.655355e-02 1.437 0 0
Hedgehog 'on' state R-HSA-5632684 2.768413e-02 1.558 0 0
Cellular response to chemical stress R-HSA-9711123 3.865259e-02 1.413 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 2.609718e-02 1.583 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 4.054662e-02 1.392 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 4.738258e-02 1.324 0 0
Regulation of gene expression in beta cells R-HSA-210745 4.075224e-02 1.390 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 4.549476e-02 1.342 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 3.524582e-02 1.453 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 4.810362e-02 1.318 0 0
Circadian clock R-HSA-9909396 4.815249e-02 1.317 0 0
Signaling by FGFR R-HSA-190236 4.935838e-02 1.307 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 4.984650e-02 1.302 0 0
Regulation of TNFR1 signaling R-HSA-5357905 4.984650e-02 1.302 0 0
Regulation of pyruvate metabolism R-HSA-9861718 4.984650e-02 1.302 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 5.198116e-02 1.284 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.240942e-02 1.281 0 0
ABC-family proteins mediated transport R-HSA-382556 5.373138e-02 1.270 0 0
Parasitic Infection Pathways R-HSA-9824443 5.387620e-02 1.269 0 0
Leishmania infection R-HSA-9658195 5.387620e-02 1.269 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 5.600799e-02 1.252 0 0
Integrin signaling R-HSA-354192 5.625705e-02 1.250 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 5.625705e-02 1.250 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 5.625705e-02 1.250 0 0
Co-stimulation by CD28 R-HSA-389356 5.646792e-02 1.248 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 5.647503e-02 1.248 0 0
Estrogen-dependent gene expression R-HSA-9018519 5.751273e-02 1.240 0 0
Regulation of endogenous retroelements R-HSA-9842860 5.834510e-02 1.234 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 5.834980e-02 1.234 0 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 5.888667e-02 1.230 0 0
The NLRP3 inflammasome R-HSA-844456 5.888667e-02 1.230 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 5.995929e-02 1.222 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 5.995929e-02 1.222 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 6.056402e-02 1.218 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.194375e-02 1.208 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.194375e-02 1.208 0 0
Toxicity of botulinum toxin type B (botB) R-HSA-5250958 6.194375e-02 1.208 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 6.194375e-02 1.208 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 6.194375e-02 1.208 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 6.485197e-02 1.188 0 0
Co-inhibition by CTLA4 R-HSA-389513 6.485197e-02 1.188 0 0
Signal transduction by L1 R-HSA-445144 6.485197e-02 1.188 0 0
Dual Incision in GG-NER R-HSA-5696400 6.504069e-02 1.187 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 6.504069e-02 1.187 0 0
Signal amplification R-HSA-392518 6.504069e-02 1.187 0 0
Calnexin/calreticulin cycle R-HSA-901042 6.504069e-02 1.187 0 0
Signaling by NOTCH2 R-HSA-1980145 6.504069e-02 1.187 0 0
Pyruvate metabolism R-HSA-70268 6.513068e-02 1.186 0 0
RSV-host interactions R-HSA-9833110 6.572204e-02 1.182 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 6.742323e-02 1.171 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 6.891745e-02 1.162 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 6.891745e-02 1.162 0 0
Disorders of transmembrane transporters R-HSA-5619115 6.939964e-02 1.159 0 0
Oncogene Induced Senescence R-HSA-2559585 6.968523e-02 1.157 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 7.043115e-02 1.152 0 0
RPIA deficiency: failed conversion of RU5P to R5P R-HSA-6791461 7.043115e-02 1.152 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 7.043115e-02 1.152 0 0
TICAM1 deficiency - HSE R-HSA-5602566 7.043115e-02 1.152 0 0
RPIA deficiency: failed conversion of R5P to RU5P R-HSA-5659996 7.043115e-02 1.152 0 0
Inhibition of PKR R-HSA-169131 7.043115e-02 1.152 0 0
Basigin interactions R-HSA-210991 7.108327e-02 1.148 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 7.108327e-02 1.148 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 7.115276e-02 1.148 0 0
Lipophagy R-HSA-9613354 7.201294e-02 1.143 0 0
5-Phosphoribose 1-diphosphate biosynthesis R-HSA-73843 7.201294e-02 1.143 0 0
ALK mutants bind TKIs R-HSA-9700645 7.201294e-02 1.143 0 0
Calcineurin activates NFAT R-HSA-2025928 7.201294e-02 1.143 0 0
GP1b-IX-V activation signalling R-HSA-430116 7.201294e-02 1.143 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 7.201294e-02 1.143 0 0
Synthesis of DNA R-HSA-69239 7.365119e-02 1.133 0 0
GPVI-mediated activation cascade R-HSA-114604 7.449555e-02 1.128 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 7.512191e-02 1.124 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 7.697501e-02 1.114 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 7.757241e-02 1.110 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 7.757241e-02 1.110 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 7.757241e-02 1.110 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 7.920982e-02 1.101 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 7.946927e-02 1.100 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 7.946927e-02 1.100 0 0
IRE1alpha activates chaperones R-HSA-381070 8.012040e-02 1.096 0 0
Binding and entry of HIV virion R-HSA-173107 8.256653e-02 1.083 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 8.256653e-02 1.083 0 0
Iron uptake and transport R-HSA-917937 8.652497e-02 1.063 0 0
Toll-like Receptor Cascades R-HSA-168898 8.808725e-02 1.055 0 0
Pentose phosphate pathway R-HSA-71336 8.989626e-02 1.046 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 9.128954e-02 1.040 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 9.216560e-02 1.035 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 9.534363e-02 1.021 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 9.534363e-02 1.021 0 0
Glycogen metabolism R-HSA-8982491 9.534363e-02 1.021 0 0
TRAF6 mediated NF-kB activation R-HSA-933542 9.849937e-02 1.007 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 1.007604e-01 0.997 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.009427e-01 0.996 0 0
PKMTs methylate histone lysines R-HSA-3214841 1.009427e-01 0.996 0 0
Peroxisomal protein import R-HSA-9033241 1.013710e-01 0.994 0 0
Regulation of beta-cell development R-HSA-186712 1.013710e-01 0.994 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 1.037671e-01 0.984 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 1.037671e-01 0.984 0 0
TRAF3 deficiency - HSE R-HSA-5602571 1.037671e-01 0.984 0 0
Breakdown of the nuclear lamina R-HSA-352238 1.037671e-01 0.984 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 1.049394e-01 0.979 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.049394e-01 0.979 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.049394e-01 0.979 0 0
Activation of RAC1 R-HSA-428540 1.049394e-01 0.979 0 0
Regulation of PTEN gene transcription R-HSA-8943724 1.061395e-01 0.974 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 1.061395e-01 0.974 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 1.061395e-01 0.974 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 1.061395e-01 0.974 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 1.061395e-01 0.974 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 1.061395e-01 0.974 0 0
Signaling by MET R-HSA-6806834 1.063686e-01 0.973 0 0
Translation of Structural Proteins R-HSA-9683701 1.066899e-01 0.972 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 1.086067e-01 0.964 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 1.105980e-01 0.956 0 0
Mitochondrial biogenesis R-HSA-1592230 1.108917e-01 0.955 0 0
PLC beta mediated events R-HSA-112043 1.110164e-01 0.955 0 0
HATs acetylate histones R-HSA-3214847 1.117003e-01 0.952 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 1.117003e-01 0.952 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.125817e-01 0.949 0 0
Activation of GABAB receptors R-HSA-991365 1.125817e-01 0.949 0 0
GABA B receptor activation R-HSA-977444 1.125817e-01 0.949 0 0
MTOR signalling R-HSA-165159 1.125817e-01 0.949 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.166719e-01 0.933 0 0
GRB2 events in EGFR signaling R-HSA-179812 1.166719e-01 0.933 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 1.166719e-01 0.933 0 0
OAS antiviral response R-HSA-8983711 1.166719e-01 0.933 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 1.214198e-01 0.916 0 0
RMTs methylate histone arginines R-HSA-3214858 1.247840e-01 0.904 0 0
Chromosome Maintenance R-HSA-73886 1.252288e-01 0.902 0 0
Parasite infection R-HSA-9664407 1.253967e-01 0.902 0 0
Leishmania phagocytosis R-HSA-9664417 1.253967e-01 0.902 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 1.253967e-01 0.902 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 1.287146e-01 0.890 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 1.294577e-01 0.888 0 0
Inflammasomes R-HSA-622312 1.294577e-01 0.888 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.310865e-01 0.882 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 1.310865e-01 0.882 0 0
Gene expression (Transcription) R-HSA-74160 1.347597e-01 0.870 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 1.359096e-01 0.867 0 0
TGFBR2 Kinase Domain Mutants in Cancer R-HSA-3645790 1.359096e-01 0.867 0 0
Signaling by RAS GAP mutants R-HSA-9753510 1.359096e-01 0.867 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 1.359096e-01 0.867 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 1.359096e-01 0.867 0 0
Loss of Function of TGFBR2 in Cancer R-HSA-3642278 1.359096e-01 0.867 0 0
ATF6B (ATF6-beta) activates chaperones R-HSA-8874177 1.359096e-01 0.867 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 1.375177e-01 0.862 0 0
XBP1(S) activates chaperone genes R-HSA-381038 1.377144e-01 0.861 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 1.410304e-01 0.851 0 0
CRMPs in Sema3A signaling R-HSA-399956 1.410304e-01 0.851 0 0
HDR through Homologous Recombination (HRR) R-HSA-5685942 1.424455e-01 0.846 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 1.458970e-01 0.836 0 0
DAP12 signaling R-HSA-2424491 1.460701e-01 0.835 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 1.460701e-01 0.835 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 1.507492e-01 0.822 0 0
GPER1 signaling R-HSA-9634597 1.507492e-01 0.822 0 0
Erythropoietin activates RAS R-HSA-9027284 1.535843e-01 0.814 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 1.535843e-01 0.814 0 0
SHC1 events in EGFR signaling R-HSA-180336 1.535843e-01 0.814 0 0
DCC mediated attractive signaling R-HSA-418885 1.535843e-01 0.814 0 0
p38MAPK events R-HSA-171007 1.535843e-01 0.814 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 1.535843e-01 0.814 0 0
RIP-mediated NFkB activation via ZBP1 R-HSA-1810476 1.535843e-01 0.814 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 1.535843e-01 0.814 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 1.535843e-01 0.814 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 1.535843e-01 0.814 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.535843e-01 0.814 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 1.535843e-01 0.814 0 0
S Phase R-HSA-69242 1.581146e-01 0.801 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.624505e-01 0.789 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 1.633317e-01 0.787 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 1.633317e-01 0.787 0 0
G0 and Early G1 R-HSA-1538133 1.633317e-01 0.787 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 1.663435e-01 0.779 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 1.663435e-01 0.779 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 1.663435e-01 0.779 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.691585e-01 0.772 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 1.693908e-01 0.771 0 0
Leishmania parasite growth and survival R-HSA-9664433 1.693908e-01 0.771 0 0
The phototransduction cascade R-HSA-2514856 1.714526e-01 0.766 0 0
Inositol phosphate metabolism R-HSA-1483249 1.717968e-01 0.765 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 1.721810e-01 0.764 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 1.721810e-01 0.764 0 0
Ca2+ pathway R-HSA-4086398 1.772453e-01 0.751 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 1.772453e-01 0.751 0 0
FCGR activation R-HSA-2029481 1.781432e-01 0.749 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 1.792771e-01 0.746 0 0
Response to metal ions R-HSA-5660526 1.792771e-01 0.746 0 0
Effects of PIP2 hydrolysis R-HSA-114508 1.811629e-01 0.742 0 0
Death Receptor Signaling R-HSA-73887 1.820020e-01 0.740 0 0
Mitochondrial protein degradation R-HSA-9837999 1.835061e-01 0.736 0 0
Meiotic synapsis R-HSA-1221632 1.857725e-01 0.731 0 0
Specification of primordial germ cells R-HSA-9827857 1.923564e-01 0.716 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.937908e-01 0.713 0 0
HCMV Late Events R-HSA-9610379 1.945188e-01 0.711 0 0
Signaling by NOTCH1 R-HSA-1980143 1.957418e-01 0.708 0 0
HCN channels R-HSA-1296061 1.967831e-01 0.706 0 0
TLR3-mediated TICAM1-dependent programmed cell death R-HSA-9013957 1.967831e-01 0.706 0 0
Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine R-HSA-9735763 1.967831e-01 0.706 0 0
Nucleotide catabolism defects R-HSA-9735786 1.967831e-01 0.706 0 0
TGFBR1 KD Mutants in Cancer R-HSA-3656532 1.967831e-01 0.706 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 1.967831e-01 0.706 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 1.967831e-01 0.706 0 0
NADE modulates death signalling R-HSA-205025 1.967831e-01 0.706 0 0
Toxicity of tetanus toxin (tetX) R-HSA-5250982 1.967831e-01 0.706 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 1.994856e-01 0.700 0 0
Signalling to ERKs R-HSA-187687 1.994856e-01 0.700 0 0
PERK regulates gene expression R-HSA-381042 1.994856e-01 0.700 0 0
Post-translational protein modification R-HSA-597592 2.015657e-01 0.696 0 0
Translation of Structural Proteins R-HSA-9694635 2.020518e-01 0.695 0 0
RNA Polymerase III Transcription Termination R-HSA-73980 2.055543e-01 0.687 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 2.055543e-01 0.687 0 0
Serotonin Neurotransmitter Release Cycle R-HSA-181429 2.055543e-01 0.687 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 2.055543e-01 0.687 0 0
Nephron development R-HSA-9831926 2.055543e-01 0.687 0 0
Telomere Maintenance R-HSA-157579 2.055710e-01 0.687 0 0
Signaling by TGFB family members R-HSA-9006936 2.073922e-01 0.683 0 0
Regulation of TP53 Activity R-HSA-5633007 2.073922e-01 0.683 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.079359e-01 0.682 0 0
Sensory processing of sound R-HSA-9659379 2.148719e-01 0.668 0 0
Dectin-2 family R-HSA-5621480 2.154872e-01 0.667 0 0
Extracellular matrix organization R-HSA-1474244 2.183356e-01 0.661 0 0
Rap1 signalling R-HSA-392517 2.188455e-01 0.660 0 0
Other interleukin signaling R-HSA-449836 2.188455e-01 0.660 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.188455e-01 0.660 0 0
NTRK2 activates RAC1 R-HSA-9032759 2.255949e-01 0.647 0 0
G2 Phase R-HSA-68911 2.255949e-01 0.647 0 0
SMAD2/3 Phosphorylation Motif Mutants in Cancer R-HSA-3304356 2.255949e-01 0.647 0 0
Resolution of AP sites via the single-nucleotide replacement pathway R-HSA-110381 2.255949e-01 0.647 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 2.255949e-01 0.647 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 2.255949e-01 0.647 0 0
Suppression of autophagy R-HSA-9636569 2.255949e-01 0.647 0 0
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes R-HSA-111464 2.255949e-01 0.647 0 0
Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK R-HSA-9931529 2.255949e-01 0.647 0 0
Reelin signalling pathway R-HSA-8866376 2.255949e-01 0.647 0 0
SMAC (DIABLO) binds to IAPs R-HSA-111463 2.255949e-01 0.647 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 2.269331e-01 0.644 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 2.308068e-01 0.637 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.322065e-01 0.634 0 0
VxPx cargo-targeting to cilium R-HSA-5620916 2.322065e-01 0.634 0 0
Protein hydroxylation R-HSA-9629569 2.322065e-01 0.634 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 2.322065e-01 0.634 0 0
Formation of definitive endoderm R-HSA-9823730 2.322065e-01 0.634 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 2.373037e-01 0.625 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 2.373037e-01 0.625 0 0
GABA receptor activation R-HSA-977443 2.385658e-01 0.622 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 2.456152e-01 0.610 0 0
Early Phase of HIV Life Cycle R-HSA-162594 2.456152e-01 0.610 0 0
Acetylcholine Neurotransmitter Release Cycle R-HSA-264642 2.456152e-01 0.610 0 0
Signalling to RAS R-HSA-167044 2.456152e-01 0.610 0 0
Formation of paraxial mesoderm R-HSA-9793380 2.463848e-01 0.608 0 0
Diseases of Immune System R-HSA-5260271 2.469496e-01 0.607 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 2.469496e-01 0.607 0 0
Generation of second messenger molecules R-HSA-202433 2.469496e-01 0.607 0 0
Activation of HOX genes during differentiation R-HSA-5619507 2.522565e-01 0.598 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 2.522565e-01 0.598 0 0
Plus-strand DNA synthesis R-HSA-164525 2.533749e-01 0.596 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 2.533749e-01 0.596 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 2.533749e-01 0.596 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 2.533749e-01 0.596 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 2.533749e-01 0.596 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 2.533749e-01 0.596 0 0
Activation of caspases through apoptosome-mediated cleavage R-HSA-111459 2.533749e-01 0.596 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 2.533749e-01 0.596 0 0
Pentose phosphate pathway disease R-HSA-6791465 2.533749e-01 0.596 0 0
Loss of Function of SMAD2/3 in Cancer R-HSA-3304349 2.533749e-01 0.596 0 0
Phosphorylation of Emi1 R-HSA-176417 2.533749e-01 0.596 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 2.533749e-01 0.596 0 0
Release of apoptotic factors from the mitochondria R-HSA-111457 2.533749e-01 0.596 0 0
SMAC, XIAP-regulated apoptotic response R-HSA-111469 2.533749e-01 0.596 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 2.533749e-01 0.596 0 0
TYSND1 cleaves peroxisomal proteins R-HSA-9033500 2.533749e-01 0.596 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 2.590509e-01 0.587 0 0
Mitochondrial calcium ion transport R-HSA-8949215 2.590509e-01 0.587 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.615452e-01 0.582 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.615452e-01 0.582 0 0
Neddylation R-HSA-8951664 2.695356e-01 0.569 0 0
Asparagine N-linked glycosylation R-HSA-446203 2.702513e-01 0.568 0 0
FGFR2 alternative splicing R-HSA-6803529 2.724947e-01 0.565 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 2.724947e-01 0.565 0 0
Dopamine Neurotransmitter Release Cycle R-HSA-212676 2.724947e-01 0.565 0 0
Neurotoxicity of clostridium toxins R-HSA-168799 2.724947e-01 0.565 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 2.762098e-01 0.559 0 0
Erythropoietin activates STAT5 R-HSA-9027283 2.801600e-01 0.553 0 0
G2/M DNA replication checkpoint R-HSA-69478 2.801600e-01 0.553 0 0
Uncoating of the HIV Virion R-HSA-162585 2.801600e-01 0.553 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 2.801600e-01 0.553 0 0
CREB phosphorylation R-HSA-199920 2.801600e-01 0.553 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 2.801600e-01 0.553 0 0
Toxicity of botulinum toxin type D (botD) R-HSA-5250955 2.801600e-01 0.553 0 0
Small interfering RNA (siRNA) biogenesis R-HSA-426486 2.801600e-01 0.553 0 0
Toxicity of botulinum toxin type F (botF) R-HSA-5250981 2.801600e-01 0.553 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 2.859286e-01 0.544 0 0
Proteasome assembly R-HSA-9907900 2.959049e-01 0.529 0 0
DAP12 interactions R-HSA-2172127 2.959049e-01 0.529 0 0
Netrin-1 signaling R-HSA-373752 2.959049e-01 0.529 0 0
Deadenylation of mRNA R-HSA-429947 2.993362e-01 0.524 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 2.993362e-01 0.524 0 0
Norepinephrine Neurotransmitter Release Cycle R-HSA-181430 2.993362e-01 0.524 0 0
FCERI mediated MAPK activation R-HSA-2871796 3.015204e-01 0.521 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 3.024170e-01 0.519 0 0
Nucleosome assembly R-HSA-774815 3.057860e-01 0.515 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 3.057860e-01 0.515 0 0
Somitogenesis R-HSA-9824272 3.057860e-01 0.515 0 0
IFNG signaling activates MAPKs R-HSA-9732724 3.059857e-01 0.514 0 0
TRIF-mediated programmed cell death R-HSA-2562578 3.059857e-01 0.514 0 0
Cohesin Loading onto Chromatin R-HSA-2470946 3.059857e-01 0.514 0 0
Recycling of eIF2:GDP R-HSA-72731 3.059857e-01 0.514 0 0
Insulin effects increased synthesis of Xylulose-5-Phosphate R-HSA-163754 3.059857e-01 0.514 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 3.059857e-01 0.514 0 0
NOSTRIN mediated eNOS trafficking R-HSA-203641 3.059857e-01 0.514 0 0
SOS-mediated signalling R-HSA-112412 3.059857e-01 0.514 0 0
CHL1 interactions R-HSA-447041 3.059857e-01 0.514 0 0
TGFBR3 regulates TGF-beta signaling R-HSA-9839389 3.059857e-01 0.514 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 3.078093e-01 0.512 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 3.105545e-01 0.508 0 0
HDMs demethylate histones R-HSA-3214842 3.127019e-01 0.505 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.127019e-01 0.505 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.127019e-01 0.505 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 3.127019e-01 0.505 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 3.127019e-01 0.505 0 0
Interleukin-7 signaling R-HSA-1266695 3.127019e-01 0.505 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 3.156799e-01 0.501 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 3.156799e-01 0.501 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 3.173496e-01 0.498 0 0
Late SARS-CoV-2 Infection Events R-HSA-9772573 3.173496e-01 0.498 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 3.260118e-01 0.487 0 0
Adrenaline,noradrenaline inhibits insulin secretion R-HSA-400042 3.260118e-01 0.487 0 0
Glutamate Neurotransmitter Release Cycle R-HSA-210500 3.260118e-01 0.487 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 3.260118e-01 0.487 0 0
Chromatin modifying enzymes R-HSA-3247509 3.263412e-01 0.486 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 3.268871e-01 0.486 0 0
Reverse Transcription of HIV RNA R-HSA-162589 3.308865e-01 0.480 0 0
Minus-strand DNA synthesis R-HSA-164516 3.308865e-01 0.480 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 3.308865e-01 0.480 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 3.308865e-01 0.480 0 0
Activation of RAS in B cells R-HSA-1169092 3.308865e-01 0.480 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 3.308865e-01 0.480 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 3.308865e-01 0.480 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 3.315525e-01 0.479 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 3.392524e-01 0.469 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 3.392524e-01 0.469 0 0
Cristae formation R-HSA-8949613 3.392524e-01 0.469 0 0
Packaging Of Telomere Ends R-HSA-171306 3.392524e-01 0.469 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 3.392524e-01 0.469 0 0
Interaction between L1 and Ankyrins R-HSA-445095 3.392524e-01 0.469 0 0
Insulin processing R-HSA-264876 3.392524e-01 0.469 0 0
RNA Polymerase II Transcription R-HSA-73857 3.447787e-01 0.462 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 3.523541e-01 0.453 0 0
HIV elongation arrest and recovery R-HSA-167287 3.524118e-01 0.453 0 0
Pausing and recovery of HIV elongation R-HSA-167290 3.524118e-01 0.453 0 0
Telomere Extension By Telomerase R-HSA-171319 3.524118e-01 0.453 0 0
ATF4 activates genes in response to endoplasmic reticulum stress R-HSA-380994 3.524118e-01 0.453 0 0
Pyroptosis R-HSA-5620971 3.524118e-01 0.453 0 0
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway R-HSA-5649702 3.548952e-01 0.450 0 0
Estrogen-stimulated signaling through PRKCZ R-HSA-9634635 3.548952e-01 0.450 0 0
Activation of the AP-1 family of transcription factors R-HSA-450341 3.548952e-01 0.450 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 3.548952e-01 0.450 0 0
ARMS-mediated activation R-HSA-170984 3.548952e-01 0.450 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 3.548952e-01 0.450 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 3.548952e-01 0.450 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 3.548952e-01 0.450 0 0
Signaling by Erythropoietin R-HSA-9006335 3.654787e-01 0.437 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.654787e-01 0.437 0 0
MAPK targets/ Nuclear events mediated by MAP kinases R-HSA-450282 3.654787e-01 0.437 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.660288e-01 0.436 0 0
Post-translational protein phosphorylation R-HSA-8957275 3.672668e-01 0.435 0 0
Regulation of insulin secretion R-HSA-422356 3.672668e-01 0.435 0 0
Establishment of Sister Chromatid Cohesion R-HSA-2468052 3.780440e-01 0.422 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 3.780440e-01 0.422 0 0
Regulation of CDH11 function R-HSA-9762292 3.780440e-01 0.422 0 0
Formation of apoptosome R-HSA-111458 3.780440e-01 0.422 0 0
Regulation of the apoptosome activity R-HSA-9627069 3.780440e-01 0.422 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 3.780440e-01 0.422 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 3.780440e-01 0.422 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 3.780440e-01 0.422 0 0
MAPK3 (ERK1) activation R-HSA-110056 3.780440e-01 0.422 0 0
Activation of BH3-only proteins R-HSA-114452 3.784429e-01 0.422 0 0
Interleukin-37 signaling R-HSA-9008059 3.784429e-01 0.422 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.815823e-01 0.418 0 0
tRNA processing R-HSA-72306 3.864977e-01 0.413 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 3.912949e-01 0.407 0 0
Chromatin organization R-HSA-4839726 3.945766e-01 0.404 0 0
G alpha (i) signalling events R-HSA-418594 3.967173e-01 0.402 0 0
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 R-HSA-933543 4.003634e-01 0.398 0 0
vRNP Assembly R-HSA-192905 4.003634e-01 0.398 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 4.003634e-01 0.398 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 4.003634e-01 0.398 0 0
Bicarbonate transporters R-HSA-425381 4.003634e-01 0.398 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 4.003634e-01 0.398 0 0
Interleukin-2 signaling R-HSA-9020558 4.003634e-01 0.398 0 0
Dissolution of Fibrin Clot R-HSA-75205 4.003634e-01 0.398 0 0
Signaling by NTRKs R-HSA-166520 4.036210e-01 0.394 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 4.040262e-01 0.394 0 0
HDACs deacetylate histones R-HSA-3214815 4.042341e-01 0.393 0 0
Response of endothelial cells to shear stress R-HSA-9860931 4.101591e-01 0.387 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 4.102095e-01 0.387 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 4.139138e-01 0.383 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 4.139138e-01 0.383 0 0
Ion homeostasis R-HSA-5578775 4.139138e-01 0.383 0 0
Nuclear RNA decay R-HSA-9930044 4.166287e-01 0.380 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 4.166287e-01 0.380 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 4.166287e-01 0.380 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 4.218832e-01 0.375 0 0
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters R-HSA-9931512 4.218832e-01 0.375 0 0
Cytochrome c-mediated apoptotic response R-HSA-111461 4.218832e-01 0.375 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 4.218832e-01 0.375 0 0
Plasmalogen biosynthesis R-HSA-75896 4.218832e-01 0.375 0 0
Mitotic Telophase/Cytokinesis R-HSA-68884 4.218832e-01 0.375 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 4.218832e-01 0.375 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 4.218832e-01 0.375 0 0
Integration of provirus R-HSA-162592 4.218832e-01 0.375 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 4.230389e-01 0.374 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 4.271689e-01 0.369 0 0
Glutamate and glutamine metabolism R-HSA-8964539 4.290954e-01 0.367 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 4.290954e-01 0.367 0 0
Generic Transcription Pathway R-HSA-212436 4.341909e-01 0.362 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 4.358298e-01 0.361 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 4.414199e-01 0.355 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 4.414199e-01 0.355 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 4.414199e-01 0.355 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 4.414199e-01 0.355 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 4.414199e-01 0.355 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 4.426319e-01 0.354 0 0
Scavenging by Class F Receptors R-HSA-3000484 4.426319e-01 0.354 0 0
RUNX3 regulates NOTCH signaling R-HSA-8941856 4.426319e-01 0.354 0 0
MET activates RAS signaling R-HSA-8851805 4.426319e-01 0.354 0 0
Trafficking and processing of endosomal TLR R-HSA-1679131 4.426319e-01 0.354 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 4.426319e-01 0.354 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 4.426319e-01 0.354 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 4.426319e-01 0.354 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 4.426319e-01 0.354 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 4.426331e-01 0.354 0 0
Stimuli-sensing channels R-HSA-2672351 4.455961e-01 0.351 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 4.489886e-01 0.348 0 0
Metabolism of polyamines R-HSA-351202 4.520857e-01 0.345 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 4.626372e-01 0.335 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 4.626372e-01 0.335 0 0
Frs2-mediated activation R-HSA-170968 4.626372e-01 0.335 0 0
Diseases of nucleotide metabolism R-HSA-9735804 4.626372e-01 0.335 0 0
HDR through MMEJ (alt-NHEJ) R-HSA-5685939 4.626372e-01 0.335 0 0
RNA Polymerase III Abortive And Retractive Initiation R-HSA-749476 4.656193e-01 0.332 0 0
RNA Polymerase III Transcription R-HSA-74158 4.656193e-01 0.332 0 0
G1/S-Specific Transcription R-HSA-69205 4.656193e-01 0.332 0 0
Cleavage of the damaged purine R-HSA-110331 4.774843e-01 0.321 0 0
Retrograde neurotrophin signalling R-HSA-177504 4.819256e-01 0.317 0 0
cGMP effects R-HSA-418457 4.819256e-01 0.317 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 4.819256e-01 0.317 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 4.819256e-01 0.317 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 4.819256e-01 0.317 0 0
Malate-aspartate shuttle R-HSA-9856872 4.819256e-01 0.317 0 0
Signaling by FGFR4 in disease R-HSA-5655291 4.819256e-01 0.317 0 0
Integration of energy metabolism R-HSA-163685 4.863707e-01 0.313 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 4.873738e-01 0.312 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 4.891871e-01 0.311 0 0
Depurination R-HSA-73927 4.891871e-01 0.311 0 0
Ion transport by P-type ATPases R-HSA-936837 4.891963e-01 0.311 0 0
Ion channel transport R-HSA-983712 4.898090e-01 0.310 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 4.942324e-01 0.306 0 0
RNA Polymerase III Chain Elongation R-HSA-73780 5.005228e-01 0.301 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 5.005228e-01 0.301 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 5.005228e-01 0.301 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 5.007242e-01 0.300 0 0
Transcriptional Regulation by E2F6 R-HSA-8953750 5.007242e-01 0.300 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 5.007242e-01 0.300 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 5.078454e-01 0.294 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 5.120923e-01 0.291 0 0
HIV Transcription Elongation R-HSA-167169 5.120923e-01 0.291 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 5.120923e-01 0.291 0 0
SLC transporter disorders R-HSA-5619102 5.138950e-01 0.289 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 5.184536e-01 0.285 0 0
Activation of the phototransduction cascade R-HSA-2485179 5.184536e-01 0.285 0 0
Phosphorylation of the APC/C R-HSA-176412 5.184536e-01 0.285 0 0
Prolonged ERK activation events R-HSA-169893 5.184536e-01 0.285 0 0
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells R-HSA-210744 5.184536e-01 0.285 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 5.184536e-01 0.285 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 5.184536e-01 0.285 0 0
Attachment and Entry R-HSA-9678110 5.184536e-01 0.285 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 5.190154e-01 0.285 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 5.232887e-01 0.281 0 0
Collagen formation R-HSA-1474290 5.265434e-01 0.279 0 0
Scavenging by Class A Receptors R-HSA-3000480 5.343111e-01 0.272 0 0
Intra-Golgi traffic R-HSA-6811438 5.343111e-01 0.272 0 0
G beta:gamma signalling through CDC42 R-HSA-8964616 5.357416e-01 0.271 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 5.357416e-01 0.271 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 5.357416e-01 0.271 0 0
mRNA decay by 5' to 3' exoribonuclease R-HSA-430039 5.357416e-01 0.271 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 5.451575e-01 0.263 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 5.451575e-01 0.263 0 0
Depyrimidination R-HSA-73928 5.451575e-01 0.263 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 5.487768e-01 0.261 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 5.524101e-01 0.258 0 0
TBC/RABGAPs R-HSA-8854214 5.558264e-01 0.255 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 5.594518e-01 0.252 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 5.594518e-01 0.252 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.607048e-01 0.251 0 0
GAB1 signalosome R-HSA-180292 5.684811e-01 0.245 0 0
Apoptotic factor-mediated response R-HSA-111471 5.684811e-01 0.245 0 0
Synaptic adhesion-like molecules R-HSA-8849932 5.684811e-01 0.245 0 0
Tie2 Signaling R-HSA-210993 5.684811e-01 0.245 0 0
Vitamin D (calciferol) metabolism R-HSA-196791 5.684811e-01 0.245 0 0
Gastrulation R-HSA-9758941 5.708336e-01 0.243 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 5.766270e-01 0.239 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 5.797824e-01 0.237 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 5.797824e-01 0.237 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 5.797824e-01 0.237 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 5.839759e-01 0.234 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 5.839759e-01 0.234 0 0
mRNA decay by 3' to 5' exoribonuclease R-HSA-429958 5.839759e-01 0.234 0 0
E2F mediated regulation of DNA replication R-HSA-113510 5.839759e-01 0.234 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 5.839759e-01 0.234 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 5.839759e-01 0.234 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 5.839759e-01 0.234 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 5.839759e-01 0.234 0 0
Cell surface interactions at the vascular wall R-HSA-202733 5.952014e-01 0.225 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 5.967068e-01 0.224 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 5.989153e-01 0.223 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 5.989153e-01 0.223 0 0
Wax and plasmalogen biosynthesis R-HSA-8848584 5.989153e-01 0.223 0 0
Creatine metabolism R-HSA-71288 5.989153e-01 0.223 0 0
Common Pathway of Fibrin Clot Formation R-HSA-140875 5.989153e-01 0.223 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 5.993205e-01 0.222 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 6.064756e-01 0.217 0 0
NGF-stimulated transcription R-HSA-9031628 6.064756e-01 0.217 0 0
SHC-mediated cascade:FGFR3 R-HSA-5654704 6.133191e-01 0.212 0 0
Regulation of MITF-M-dependent genes involved in apoptosis R-HSA-9824594 6.133191e-01 0.212 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 6.168568e-01 0.210 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.235584e-01 0.205 0 0
Signaling by FGFR2 in disease R-HSA-5655253 6.254718e-01 0.204 0 0
Interferon gamma signaling R-HSA-877300 6.267650e-01 0.203 0 0
RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-76066 6.272065e-01 0.203 0 0
SHC-mediated cascade:FGFR4 R-HSA-5654719 6.272065e-01 0.203 0 0
FRS-mediated FGFR3 signaling R-HSA-5654706 6.272065e-01 0.203 0 0
Androgen biosynthesis R-HSA-193048 6.272065e-01 0.203 0 0
Attachment and Entry R-HSA-9694614 6.272065e-01 0.203 0 0
Signaling by PDGFR in disease R-HSA-9671555 6.272065e-01 0.203 0 0
Ribavirin ADME R-HSA-9755088 6.272065e-01 0.203 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 6.272065e-01 0.203 0 0
Notch-HLH transcription pathway R-HSA-350054 6.405960e-01 0.193 0 0
RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76071 6.405960e-01 0.193 0 0
RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76061 6.405960e-01 0.193 0 0
FRS-mediated FGFR4 signaling R-HSA-5654712 6.405960e-01 0.193 0 0
LDL clearance R-HSA-8964038 6.405960e-01 0.193 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 6.405960e-01 0.193 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 6.405960e-01 0.193 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 6.437496e-01 0.191 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 6.437496e-01 0.191 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 6.526212e-01 0.185 0 0
Nucleotide biosynthesis R-HSA-8956320 6.526212e-01 0.185 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 6.535053e-01 0.185 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 6.535053e-01 0.185 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 6.535053e-01 0.185 0 0
Growth hormone receptor signaling R-HSA-982772 6.535053e-01 0.185 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 6.613159e-01 0.180 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 6.659517e-01 0.177 0 0
SHC-mediated cascade:FGFR1 R-HSA-5654688 6.659517e-01 0.177 0 0
Mitochondrial RNA degradation R-HSA-9836573 6.659517e-01 0.177 0 0
Complex III assembly R-HSA-9865881 6.659517e-01 0.177 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 6.659517e-01 0.177 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 6.674745e-01 0.176 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 6.741802e-01 0.171 0 0
Sema4D in semaphorin signaling R-HSA-400685 6.779518e-01 0.169 0 0
FRS-mediated FGFR1 signaling R-HSA-5654693 6.779518e-01 0.169 0 0
Laminin interactions R-HSA-3000157 6.779518e-01 0.169 0 0
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes R-HSA-9931510 6.895215e-01 0.161 0 0
Myogenesis R-HSA-525793 6.895215e-01 0.161 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 6.895215e-01 0.161 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 6.895215e-01 0.161 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 6.895215e-01 0.161 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 7.006762e-01 0.154 0 0
SHC-mediated cascade:FGFR2 R-HSA-5654699 7.006762e-01 0.154 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 7.006762e-01 0.154 0 0
Signaling by FGFR3 in disease R-HSA-5655332 7.006762e-01 0.154 0 0
Neurotransmitter release cycle R-HSA-112310 7.007721e-01 0.154 0 0
Base Excision Repair R-HSA-73884 7.007721e-01 0.154 0 0
Extension of Telomeres R-HSA-180786 7.021852e-01 0.154 0 0
Rab regulation of trafficking R-HSA-9007101 7.043645e-01 0.152 0 0
G alpha (q) signalling events R-HSA-416476 7.094872e-01 0.149 0 0
tRNA Aminoacylation R-HSA-379724 7.098496e-01 0.149 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 7.114308e-01 0.148 0 0
Formation of the Early Elongation Complex R-HSA-113418 7.114308e-01 0.148 0 0
FRS-mediated FGFR2 signaling R-HSA-5654700 7.114308e-01 0.148 0 0
RUNX2 regulates osteoblast differentiation R-HSA-8940973 7.114308e-01 0.148 0 0
Impaired BRCA2 binding to RAD51 R-HSA-9709570 7.217996e-01 0.142 0 0
mRNA Capping R-HSA-72086 7.217996e-01 0.142 0 0
Nitric oxide stimulates guanylate cyclase R-HSA-392154 7.217996e-01 0.142 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 7.217996e-01 0.142 0 0
DARPP-32 events R-HSA-180024 7.217996e-01 0.142 0 0
NCAM signaling for neurite out-growth R-HSA-375165 7.246837e-01 0.140 0 0
Signaling by PDGF R-HSA-186797 7.246837e-01 0.140 0 0
Activation of the pre-replicative complex R-HSA-68962 7.317965e-01 0.136 0 0
RNA Polymerase III Transcription Initiation R-HSA-76046 7.317965e-01 0.136 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 7.317965e-01 0.136 0 0
NOTCH3 Intracellular Domain Regulates Transcription R-HSA-9013508 7.317965e-01 0.136 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 7.317965e-01 0.136 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 7.317965e-01 0.136 0 0
Potential therapeutics for SARS R-HSA-9679191 7.339753e-01 0.134 0 0
MITF-M-dependent gene expression R-HSA-9856651 7.339753e-01 0.134 0 0
Bacterial Infection Pathways R-HSA-9824439 7.362412e-01 0.133 0 0
Molecules associated with elastic fibres R-HSA-2129379 7.414347e-01 0.130 0 0
Downstream signal transduction R-HSA-186763 7.414347e-01 0.130 0 0
Formation of the cornified envelope R-HSA-6809371 7.416266e-01 0.130 0 0
Diseases of mitotic cell cycle R-HSA-9675126 7.507272e-01 0.125 0 0
Kidney development R-HSA-9830369 7.589809e-01 0.120 0 0
HDR through Single Strand Annealing (SSA) R-HSA-5685938 7.596862e-01 0.119 0 0
G-protein beta:gamma signalling R-HSA-397795 7.596862e-01 0.119 0 0
Activation of ATR in response to replication stress R-HSA-176187 7.596862e-01 0.119 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 7.596862e-01 0.119 0 0
Transcription of the HIV genome R-HSA-167172 7.653801e-01 0.116 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 7.653801e-01 0.116 0 0
eNOS activation R-HSA-203615 7.766514e-01 0.110 0 0
Defective homologous recombination repair (HRR) due to BRCA2 loss of function R-HSA-9701190 7.766514e-01 0.110 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 7.766514e-01 0.110 0 0
Diseases of DNA Double-Strand Break Repair R-HSA-9675136 7.766514e-01 0.110 0 0
ECM proteoglycans R-HSA-3000178 7.836990e-01 0.106 0 0
Formation of WDR5-containing histone-modifying complexes R-HSA-9772755 7.846802e-01 0.105 0 0
Presynaptic phase of homologous DNA pairing and strand exchange R-HSA-5693616 7.846802e-01 0.105 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 7.846802e-01 0.105 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 7.846802e-01 0.105 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 7.846802e-01 0.105 0 0
Formation of Fibrin Clot (Clotting Cascade) R-HSA-140877 7.924208e-01 0.101 0 0
RUNX2 regulates bone development R-HSA-8941326 7.924208e-01 0.101 0 0
Triglyceride catabolism R-HSA-163560 7.924208e-01 0.101 0 0
FGFR2 mutant receptor activation R-HSA-1839126 7.924208e-01 0.101 0 0
RET signaling R-HSA-8853659 7.924208e-01 0.101 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 7.998836e-01 0.097 0 0
Collagen chain trimerization R-HSA-8948216 7.998836e-01 0.097 0 0
Metabolism of folate and pterines R-HSA-196757 7.998836e-01 0.097 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 8.007501e-01 0.097 0 0
Signaling by FGFR in disease R-HSA-1226099 8.007501e-01 0.097 0 0
GPCR downstream signalling R-HSA-388396 8.038272e-01 0.095 0 0
Elastic fibre formation R-HSA-1566948 8.070786e-01 0.093 0 0
Purine salvage R-HSA-74217 8.070786e-01 0.093 0 0
MET promotes cell motility R-HSA-8875878 8.070786e-01 0.093 0 0
Homologous DNA Pairing and Strand Exchange R-HSA-5693579 8.070786e-01 0.093 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 8.070786e-01 0.093 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 8.140153e-01 0.089 0 0
Expression of BMAL (ARNTL), CLOCK, and NPAS2 R-HSA-9931509 8.140153e-01 0.089 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 8.207030e-01 0.086 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 8.207030e-01 0.086 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 8.207030e-01 0.086 0 0
Maturation of TCA enzymes and regulation of TCA cycle R-HSA-9854311 8.207030e-01 0.086 0 0
Tryptophan catabolism R-HSA-71240 8.207030e-01 0.086 0 0
Mitochondrial tRNA aminoacylation R-HSA-379726 8.207030e-01 0.086 0 0
Interleukin-2 family signaling R-HSA-451927 8.207030e-01 0.086 0 0
Integrin cell surface interactions R-HSA-216083 8.216257e-01 0.085 0 0
Interleukin-10 signaling R-HSA-6783783 8.216257e-01 0.085 0 0
G alpha (s) signalling events R-HSA-418555 8.228923e-01 0.085 0 0
Resolution of Abasic Sites (AP sites) R-HSA-73933 8.271506e-01 0.082 0 0
Maturation of spike protein R-HSA-9694548 8.271506e-01 0.082 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 8.333667e-01 0.079 0 0
HIV Transcription Initiation R-HSA-167161 8.333667e-01 0.079 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 8.333667e-01 0.079 0 0
Signaling by FGFR1 in disease R-HSA-5655302 8.333667e-01 0.079 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 8.393596e-01 0.076 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 8.451374e-01 0.073 0 0
Synthesis of very long-chain fatty acyl-CoAs R-HSA-75876 8.451374e-01 0.073 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 8.498305e-01 0.071 0 0
Methylation R-HSA-156581 8.507077e-01 0.070 0 0
Synthesis of Leukotrienes (LT) and Eoxins (EX) R-HSA-2142691 8.507077e-01 0.070 0 0
Visual phototransduction R-HSA-2187338 8.523799e-01 0.069 0 0
Protein-protein interactions at synapses R-HSA-6794362 8.534789e-01 0.069 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 8.560779e-01 0.067 0 0
Peptide hormone metabolism R-HSA-2980736 8.569709e-01 0.067 0 0
Signaling by TGFBR3 R-HSA-9839373 8.612553e-01 0.065 0 0
Diseases of DNA repair R-HSA-9675135 8.612553e-01 0.065 0 0
Peptide ligand-binding receptors R-HSA-375276 8.685163e-01 0.061 0 0
Chemokine receptors bind chemokines R-HSA-380108 8.756983e-01 0.058 0 0
Neurexins and neuroligins R-HSA-6794361 8.886401e-01 0.051 0 0
Glucuronidation R-HSA-156588 8.965116e-01 0.047 0 0
NRAGE signals death through JNK R-HSA-193648 9.038275e-01 0.044 0 0
Cardiac conduction R-HSA-5576891 9.041275e-01 0.044 0 0
Metabolism of nucleotides R-HSA-15869 9.056539e-01 0.043 0 0
IRS-mediated signalling R-HSA-112399 9.072895e-01 0.042 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 9.106271e-01 0.041 0 0
Triglyceride metabolism R-HSA-8979227 9.138448e-01 0.039 0 0
Amino acid transport across the plasma membrane R-HSA-352230 9.138448e-01 0.039 0 0
PI Metabolism R-HSA-1483255 9.179723e-01 0.037 0 0
Signaling by GPCR R-HSA-372790 9.194560e-01 0.036 0 0
Nucleotide salvage R-HSA-8956321 9.199372e-01 0.036 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 9.199372e-01 0.036 0 0
Collagen degradation R-HSA-1442490 9.199372e-01 0.036 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 9.228202e-01 0.035 0 0
Heme signaling R-HSA-9707616 9.228202e-01 0.035 0 0
Complex I biogenesis R-HSA-6799198 9.255995e-01 0.034 0 0
CD22 mediated BCR regulation R-HSA-5690714 9.282789e-01 0.032 0 0
IGF1R signaling cascade R-HSA-2428924 9.282789e-01 0.032 0 0
Insulin receptor signalling cascade R-HSA-74751 9.282789e-01 0.032 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 9.308620e-01 0.031 0 0
tRNA modification in the nucleus and cytosol R-HSA-6782315 9.333522e-01 0.030 0 0
SLC-mediated transport of amino acids R-HSA-9958863 9.357528e-01 0.029 0 0
Metabolism of steroid hormones R-HSA-196071 9.357528e-01 0.029 0 0
Fatty acyl-CoA biosynthesis R-HSA-75105 9.424491e-01 0.026 0 0
Metabolism of cofactors R-HSA-8978934 9.445226e-01 0.025 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 9.446497e-01 0.025 0 0
Purine catabolism R-HSA-74259 9.465215e-01 0.024 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 9.520970e-01 0.021 0 0
Nuclear Receptor transcription pathway R-HSA-383280 9.570921e-01 0.019 0 0
G alpha (12/13) signalling events R-HSA-416482 9.570921e-01 0.019 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 9.586388e-01 0.018 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 9.586388e-01 0.018 0 0
Cytoprotection by HMOX1 R-HSA-9707564 9.642885e-01 0.016 0 0
Keratinization R-HSA-6805567 9.651982e-01 0.015 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 9.691677e-01 0.014 0 0
Sulfur amino acid metabolism R-HSA-1614635 9.691677e-01 0.014 0 0
Respiratory electron transport R-HSA-611105 9.750150e-01 0.011 0 0
Signaling by Insulin receptor R-HSA-74752 9.761595e-01 0.010 0 0
Potassium Channels R-HSA-1296071 9.801616e-01 0.009 0 0
FOXO-mediated transcription R-HSA-9614085 9.822332e-01 0.008 0 0
Platelet homeostasis R-HSA-418346 9.867615e-01 0.006 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 9.934215e-01 0.003 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.944649e-01 0.002 0 0
Nucleotide catabolism R-HSA-8956319 9.949167e-01 0.002 0 0
Adipogenesis R-HSA-9843745 9.954487e-01 0.002 0 0
Sensory perception of taste R-HSA-9717189 9.954487e-01 0.002 0 0
Degradation of the extracellular matrix R-HSA-1474228 9.956134e-01 0.002 0 0
Diseases of metabolism R-HSA-5668914 9.971297e-01 0.001 0 0
Arachidonate metabolism R-HSA-2142753 9.980512e-01 0.001 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.992324e-01 0.000 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.993171e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.996208e-01 0.000 0 0
Metabolism of steroids R-HSA-8957322 9.997061e-01 0.000 0 0
Drug ADME R-HSA-9748784 9.998424e-01 0.000 0 0
Phospholipid metabolism R-HSA-1483257 9.998852e-01 0.000 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.998990e-01 0.000 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.999830e-01 0.000 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.999895e-01 0.000 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.999968e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.999977e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.999980e-01 0.000 0 0
Biological oxidations R-HSA-211859 9.999996e-01 0.000 0 0
Metabolism R-HSA-1430728 9.999998e-01 0.000 0 0
Sensory Perception R-HSA-9709957 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 -0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways