MLK3
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0A2R8Y4L2 | S95 | Sugiyama | HNRNPA1L3 HNRNPA1P48 | RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | S939 | Sugiyama | POTEF A26C1B | VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE |
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| A6NMY6 | S134 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD |
| A6NMY6 | S164 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGS |
| A6NMY6 | T163 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG |
| O00165 | S153 | Sugiyama | HAX1 HS1BP1 | PDSHQPRIFGGVLESDARSEsPQPAPDWGsQRPFHRFDDVW |
| O00273 | S305 | Sugiyama | DFFA DFF1 DFF45 H13 | VQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDLQNPKR |
| O00273 | T300 | Sugiyama | DFFA DFF1 DFF45 H13 | KKTETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDL |
| O00299 | S156 | Sugiyama | CLIC1 G6 NCC27 | ALKVLDNyLTsPLPEEVDEtsAEDEGVsQRKFLDGNELTLA |
| O00299 | S163 | Sugiyama | CLIC1 G6 NCC27 | yLTsPLPEEVDEtsAEDEGVsQRKFLDGNELTLADCNLLPK |
| O00410 | S974 | Sugiyama | IPO5 KPNB3 RANBP5 | VIQSADSKTKENVNAtENCIsAVGKIMKFKPDCVNVEEVLP |
| O00469 | S83 | Sugiyama | PLOD2 | NYTVKVLGQGEEWRGGDGINsIGGGQKVRLMKEVMEHYADQ |
| O14734 | S111 | Sugiyama | ACOT8 ACTEIII PTE1 | KLPVLYQVERTRTGsSFSVRsVKAVQHGKPIFICQASFQQA |
| O15127 | T109 | Sugiyama | SCAMP2 | QEELDRKAAELERKERELQNtVANLHVRQNNWPPLPSWCPV |
| O15212 | S53 | Sugiyama | PFDN6 HKE2 PFD6 | LEAQLtENNIVKEELALLDGsNVVFKLLGPVLVKQELGEAR |
| O15357 | S787 | Sugiyama | INPPL1 SHIP2 | IEFYSTCLEEYKKSFENDAQsSDNINFLKVQWSSRQLPTLK |
| O43175 | T89 | Sugiyama | PHGDH PGDH3 | KLQVVGRAGtGVDNVDLEAAtRKGILVMNTPNGNSLSAAEL |
| O43399 | S152 | Sugiyama | TPD52L2 | TLsQAGQKtsAALstVGsAIsRKLGDMRNsAtFKsFEDRVG |
| O43707 | T443 | Sugiyama | ACTN4 | sIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDL |
| O43707 | T445 | Sugiyama | ACTN4 | HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA |
| O43707 | T756 | Sugiyama | ACTN4 | WEQLLTTIARTINEVENQILtRDAKGIsQEQMQEFRASFNH |
| O43707 | Y441 | Sugiyama | ACTN4 | KAsIHEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEs |
| O43852 | S69 | Sugiyama | CALU | HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt |
| O43852 | T65 | Sugiyama | CALU | FDyDHDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKD |
| O43852 | T89 | Sugiyama | CALU | sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV |
| O60271 | S194 | Sugiyama | SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 | LERTKLHQLsGsDQLEstAHsRIRKERPIsLGIFPLPAGDG |
| O60361 | S105 | Sugiyama | NME2P1 | KPGtIRGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELV |
| O60361 | S84 | Sugiyama | NME2P1 | EGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHG |
| O60664 | S175 | Sugiyama | PLIN3 M6PRBP1 TIP47 | RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK |
| O60716 | S252 | Sugiyama | CTNND1 KIAA0384 | sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL |
| O60841 | S196 | Sugiyama | EIF5B IF2 KIAA0741 | ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN |
| O75534 | S598 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | KVNKtHsVNGItEEADPTIysGKVIRPLRSVDPTQTEYQGM |
| O95372 | S212 | Sugiyama | LYPLA2 APT2 | RSVVTPARVQFKTYPGVMHSsCPQEMAAVKEFLEKLLPPV_ |
| O95817 | S165 | Sugiyama | BAG3 BIS | tQPDKQCGQVAAAAAAQPPAsHGPERsQsPAAsDCsssSsS |
| O95831 | T188 | Sugiyama | AIFM1 AIF PDCD8 | LPYMRPPLSKELWFSDDPNVtKtLRFKQWNGKERSIYFQPP |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P04040 | T441 | Sugiyama | CAT | HSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEEQRKRLCE |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T124 | Sugiyama | ALDOA ALDA | VVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGAD |
| P04075 | T37 | Sugiyama | ALDOA ALDA | sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR |
| P04083 | S170 | Sugiyama | ANXA1 ANX1 LPC1 | RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE |
| P04083 | S173 | Sugiyama | ANXA1 ANX1 LPC1 | NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG |
| P04083 | T172 | Sugiyama | ANXA1 ANX1 LPC1 | INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04792 | S176 | Sugiyama | HSPB1 HSP27 HSP28 | sLsPEGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEA |
| P04792 | S26 | Sugiyama | HSPB1 HSP27 HSP28 | VPFsLLRGPsWDPFRDWyPHsRLFDQAFGLPRLPEEWSQWL |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05023 | S675 | Sugiyama | ATP1A1 | VNPRDAKACVVHGsDLKDMTsEQLDDILKyHtEIVFARTsP |
| P05362 | T448 | Sugiyama | ICAM1 | ELKCLKDGtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTR |
| P05386 | S101 | Sugiyama | RPLP1 RRP1 | APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______ |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S102 | Sugiyama | RPLP2 D11S2243E RPP2 | PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S19 | Sugiyama | RPLP2 D11S2243E RPP2 | __MRyVAsyLLAALGGNssPsAKDIKKILDsVGIEADDDRL |
| P05387 | S29 | Sugiyama | RPLP2 D11S2243E RPP2 | LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK |
| P05388 | S307 | Sugiyama | RPLP0 | AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________ |
| P05455 | S325 | Sugiyama | SSB | VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA |
| P05783 | S401 | Sugiyama | KRT18 CYK18 PIG46 | RRLLEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVVsE |
| P05787 | S258 | Sugiyama | KRT8 CYK8 | QISDTSVVLsMDNSRsLDMDsIIAEVKAQyEDIANRsRAEA |
| P05787 | S280 | Sugiyama | KRT8 CYK8 | IAEVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDL |
| P05787 | S291 | Sugiyama | KRT8 CYK8 | ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN |
| P05787 | S410 | Sugiyama | KRT8 CYK8 | TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL |
| P06733 | S268 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S291 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA |
| P06733 | S353 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs |
| P06733 | S79 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GKGVSKAVEHINKtIAPALVsKKLNVtEQEKIDKLMIEMDG |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T55 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP |
| P06748 | S137 | Sugiyama | NPM1 NPM | VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK |
| P07108 | T36 | Sugiyama | DBI | LKTKPsDEEMLFIyGHyKQAtVGDINtERPGMLDFTGKAKW |
| P07108 | T42 | Sugiyama | DBI | DEEMLFIyGHyKQAtVGDINtERPGMLDFTGKAKWDAWNEL |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T18 | Sugiyama | LDHB | ___MATLKEKLIAPVAEEEAtVPNNKITVVGVGQVGMACAI |
| P07237 | S331 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | ECPAVRLITLEEEMTKyKPEsEELtAERItEFCHRFLEGKI |
| P07355 | S134 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD |
| P07355 | S164 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGs |
| P07355 | T163 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | INRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDG |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | T107 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC |
| P07737 | S133 | Sugiyama | PFN1 | LMGKEGVHGGLINKKCyEMAsHLRRsQY_____________ |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07737 | S85 | Sugiyama | PFN1 | tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK |
| P07814 | S1473 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | CEDWIKKtTARDQDLEPGAPsMGAKSLCIPFKPLCELQPGA |
| P07814 | S335 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt |
| P07814 | S880 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | LKAQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPE |
| P07814 | S882 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | AQYKEKTGKEyIPGQPPLsQssDssPtRNsEPAGLEtPEAK |
| P07814 | T1105 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | SALEKEKTHVADFAPEVAWVtRSGKTELAEPIAIRPTsEtV |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S165 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK |
| P07900 | S169 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | TVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILH |
| P07900 | S391 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P07900 | S50 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S72 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | ssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQDRtLtIV |
| P07900 | T195 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG |
| P08151 | S1089 | PSP | GLI1 GLI | GSsGHtPPPsGPPNMAVGNMsVLLRSLPGETEFLNSSA___ |
| P08151 | T394 | PSP | GLI1 GLI | tDPSSLRKHVKTVHGPDAHVtKRHRGDGPLPRAPsISTVEP |
| P08195 | S253 | Sugiyama | SLC3A2 MDU1 | FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA |
| P08195 | S292 | Sugiyama | SLC3A2 MDU1 | VAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNY |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | T275 | Sugiyama | SLC3A2 MDU1 | KVKGLVLGPIHKNQKDDVAQtDLLQIDPNFGsKEDFDsLLQ |
| P08238 | S160 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK |
| P08238 | S164 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | VVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILH |
| P08238 | S383 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S470 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | S535 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| P08238 | S67 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERtLtLV |
| P08238 | T190 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | Y457 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK |
| P08670 | S438 | Sugiyama | VIM | FssLNLREtNLDsLPLVDtHsKRTLLIKtVEtRDGQVINEt |
| P08865 | S75 | Sugiyama | RPSA LAMBR LAMR1 | WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P09496 | S236 | Sugiyama | CLTA | RLCDFNPKSSKQAKDVSRMRsVLIsLKQAPLVH________ |
| P09496 | S240 | Sugiyama | CLTA | FNPKSSKQAKDVSRMRsVLIsLKQAPLVH____________ |
| P09497 | S205 | Sugiyama | CLTB | EETPGTEWEKVAQLCDFNPKssKQCKDVSRLRsVLMsLKQT |
| P09497 | S206 | Sugiyama | CLTB | ETPGTEWEKVAQLCDFNPKssKQCKDVSRLRsVLMsLKQTP |
| P09651 | S95 | Sugiyama | HNRNPA1 HNRPA1 | RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| P09972 | S132 | Sugiyama | ALDOC ALDC | GVVPLAGtDGEtttQGLDGLsERCAQYKKDGADFAKWRCVL |
| P09972 | T125 | Sugiyama | ALDOC ALDC | VGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGADF |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | S54 | Sugiyama | TUBA3C TUBA2 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P0DPH7 | T51 | Sugiyama | TUBA3C TUBA2 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P0DPH7 | T56 | Sugiyama | TUBA3C TUBA2 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| P10412 | S55 | Sugiyama | H1-4 H1F4 HIST1H1E | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P10809 | S247 | Sugiyama | HSPD1 HSP60 | yFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEIANAH |
| P10809 | S67 | Sugiyama | HSPD1 HSP60 | LADAVAVTMGPKGRtVIIEQsWGsPKVTKDGVtVAKsIDLK |
| P11142 | S221 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | GGGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHF |
| P11142 | S340 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | S85 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV |
| P11142 | T163 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11142 | T45 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11586 | S129 | Sugiyama | MTHFD1 MTHFC MTHFD | INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P12268 | S508 | Sugiyama | IMPDH2 IMPD2 | LKFEKRtssAQVEGGVHsLHsyEKRLF______________ |
| P12268 | Y509 | Sugiyama | IMPDH2 IMPD2 | KFEKRtssAQVEGGVHsLHsyEKRLF_______________ |
| P12270 | T1518 | Sugiyama | TPR | ENLQKTLSEKETEARNLQEQtVQLQSELSRLRQDLQDRTTQ |
| P12277 | S129 | Sugiyama | CKB CKBB | DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG |
| P12814 | T737 | Sugiyama | ACTN1 | WEQLLTTIARTINEVENQILtRDAKGIsQEQMNEFRAsFNH |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S38 | Sugiyama | EEF2 EF2 | NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | Y579 | Sugiyama | EEF2 EF2 | KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH |
| P13667 | S126 | Sugiyama | PDIA4 ERP70 ERP72 | NILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILKKG |
| P13667 | S379 | Sugiyama | PDIA4 ERP70 ERP72 | QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P13987 | T76 | Sugiyama | CD59 MIC11 MIN1 MIN2 MIN3 MSK21 | AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF |
| P14209 | S168 | Sugiyama | CD99 MIC2 MIC2X MIC2Y | YQKKKLCFKENAEQGEVDMEsHRNANAEPAVQRtLLEK___ |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14314 | S478 | Sugiyama | PRKCSH G19P1 | DKFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPS |
| P14314 | T134 | Sugiyama | PRKCSH G19P1 | NtCKEKGRKEREsLQQMAEVtREGFRLKKILIEDWKKAREE |
| P14314 | T469 | Sugiyama | PRKCSH G19P1 | WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt |
| P14314 | T479 | Sugiyama | PRKCSH G19P1 | KFSAMKyEQGtGCWQGPNRstTVRLLCGKEtMVtStTEPSR |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S205 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD |
| P14618 | S77 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs |
| P14618 | S97 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP |
| P14618 | T50 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN |
| P14618 | T80 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | tLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAs |
| P14618 | T87 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP |
| P14618 | T95 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | NFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTK |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | S172 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | VGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSELI |
| P14625 | S64 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR |
| P14625 | S674 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | WsGNMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLI |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14649 | T101 | Sugiyama | MYL6B MLC1SA | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDELKSRR |
| P15104 | S322 | Sugiyama | GLUL GLNS | GFHETSNINDFSAGVANRsAsIRIPRTVGQEKKGYFEDRRP |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15531 | S99 | Sugiyama | NME1 NDPKA NM23 | EGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHG |
| P16402 | S56 | Sugiyama | H1-3 H1F3 HIST1H1D | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P16403 | S55 | Sugiyama | H1-2 H1F2 HIST1H1C | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P17066 | T228 | Sugiyama | HSPA6 HSP70B' | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P17066 | T47 | Sugiyama | HSPA6 HSP70B' | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P17812 | S575 | Sugiyama | CTPS1 CTPS | LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____ |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18621 | T12 | Sugiyama | RPL17 | _________MVRysLDPENPtKsCKSRGSNLRVHFKNtRET |
| P18669 | S155 | Sugiyama | PGAM1 PGAMA CDABP0006 | NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI |
| P18669 | T159 | Sugiyama | PGAM1 PGAMA CDABP0006 | DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK |
| P20042 | S160 | Sugiyama | EIF2S2 EIF2B | LEKDEALEDEDNKKDDGIsFsNQtGPAWAGSERDytyEELL |
| P20290 | T133 | Sugiyama | BTF3 NACB OK/SW-cl.8 | GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ |
| P20290 | T140 | Sugiyama | BTF3 NACB OK/SW-cl.8 | NPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLGADsLt |
| P20618 | S151 | Sugiyama | PSMB1 PSC5 | PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA |
| P20618 | S157 | Sugiyama | PSMB1 PSC5 | IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL |
| P20618 | S162 | Sugiyama | PSMB1 PSC5 | DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG |
| P20674 | T105 | Sugiyama | COX5A | EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY |
| P21108 | S10 | Sugiyama | PRPS1L1 PRPS3 PRPSL | ___________MPNIKIFsGssHQDLSQKIADRLGLELGKV |
| P22314 | S56 | Sugiyama | UBA1 A1S9T UBE1 | VPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSVL |
| P22392 | S120 | Sugiyama | NME2 NM23B | KPGtIRGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELV |
| P22392 | S99 | Sugiyama | NME2 NM23B | EGLNVVKTGRVMLGEtNPADsKPGtIRGDFCIQVGRNIIHG |
| P22626 | S198 | Sugiyama | HNRNPA2B1 HNRPA2B1 | NGHNAEVRKALsRQEMQEVQssRsGRGGNFGFGDsRGGGGN |
| P23246 | S283 | Sugiyama | SFPQ PSF | GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN |
| P23381 | S358 | Sugiyama | WARS1 IFI53 WARS WRS | TFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFs |
| P23497 | S180 | Sugiyama | SP100 | EEREERsGLQLsLEQGtGENsFRSLTWPPsGsPsHAGttPP |
| P23526 | S183 | Sugiyama | AHCY SAHH | NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI |
| P23526 | T157 | Sugiyama | AHCY SAHH | NLIHTKYPQLLPGIRGIsEEtTTGVHNLyKMMANGILKVPA |
| P23526 | T185 | Sugiyama | AHCY SAHH | yKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGIKR |
| P23528 | T63 | Sugiyama | CFL1 CFL | DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P23588 | S122 | Sugiyama | EIF4B | NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA |
| P23588 | S207 | Sugiyama | EIF4B | DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR |
| P24752 | S218 | Sugiyama | ACAT1 ACAT MAT | ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV |
| P24752 | T220 | Sugiyama | ACAT1 ACAT MAT | TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV |
| P25398 | S107 | Sugiyama | RPS12 | EWVGLCKIDREGKPRKVVGCsCVVVKDYGKESQAKDVIEEy |
| P25786 | T11 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P27144 | T199 | Sugiyama | AK4 AK3 AK3L1 | KPVIELYKSRGVLHQFsGtEtNKIWPYVYTLFSNKITPIQS |
| P27797 | S193 | Sugiyama | CALR CRTC | tLIVRPDNtyEVKIDNsQVEsGsLEDDWDFLPPKKIKDPDA |
| P27797 | S35 | Sugiyama | CALR CRTC | AVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGK |
| P27797 | S40 | Sugiyama | CALR CRTC | AVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGKFyGDE |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P29401 | S332 | Sugiyama | TKT | GDKIATRKAYGQALAKLGHAsDRIIALDGDtKNstFsEIFK |
| P29401 | T342 | Sugiyama | TKT | GQALAKLGHAsDRIIALDGDtKNstFsEIFKKEHPDRFIEC |
| P29692 | S162 | Sugiyama | EEF1D EF1D | AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S71 | Sugiyama | EEF1D EF1D | ARARENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVEN |
| P29692 | S74 | Sugiyama | EEF1D EF1D | RENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVENQsL |
| P29966 | S26 | Sugiyama | MARCKS MACS PRKCSL | SKTAAKGEAAAERPGEAAVAssPsKANGQENGHVKVNGDAs |
| P30040 | S219 | Sugiyama | ERP29 C12orf8 ERP28 | AEQyLKIMGKILDQGEDFPAsEMTRIARLIEKNKMSDGKKE |
| P30041 | S186 | Sugiyama | PRDX6 AOP2 KIAA0106 | SLQLTAEKRVAtPVDWKDGDsVMVLPtIPEEEAKKLFPKGV |
| P30041 | T48 | Sugiyama | PRDX6 AOP2 KIAA0106 | FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL |
| P30041 | T49 | Sugiyama | PRDX6 AOP2 KIAA0106 | LGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKLI |
| P30041 | T95 | Sugiyama | PRDX6 AOP2 KIAA0106 | SVEDHLAWSKDINAyNCEEPtEKLPFPIIDDRNRELAILLG |
| P30043 | S202 | Sugiyama | BLVRB FLR SCAN | GHFMLRCLttDEyDGHstyPsHQyQ________________ |
| P30044 | S171 | Sugiyama | PRDX5 ACR1 SBBI10 | ADPTGAFGKEtDLLLDDsLVsIFGNRRLKRFsMVVQDGIVK |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30050 | S26 | Sugiyama | RPL12 | DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | S60 | Sugiyama | PEBP1 PBP PEBP | VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK |
| P30101 | S126 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | FRDGEEAGAyDGPRtADGIVsHLKKQAGPASVPLRTEEEFK |
| P30101 | S343 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | IPVVAIRTAKGEKFVMQEEFsRDGKALERFLQDyFDGNLKR |
| P31150 | S316 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM |
| P31327 | S564 | Sugiyama | CPS1 | TEDRQLFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPV |
| P31327 | S569 | Sugiyama | CPS1 | LFSDKLNEINEKIAPsFAVEsIEDALKAADTIGyPVMIRSA |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P31327 | T326 | Sugiyama | CPS1 | AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP |
| P31939 | S450 | Sugiyama | ATIC PURH OK/SW-cl.86 | SNSVCYAKNGQVIGIGAGQQsRIHCTRLAGDKANyWWLRHH |
| P31943 | S104 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | EVFKSNNVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P31943 | T287 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | CFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIyN |
| P31948 | S16 | Sugiyama | STIP1 | _____MEQVNELKEKGNKALsVGNIDDALQCysEAIKLDPH |
| P31948 | S28 | Sugiyama | STIP1 | KEKGNKALsVGNIDDALQCysEAIKLDPHNHVLysNRsAAy |
| P33176 | S443 | Sugiyama | KIF5B KNS KNS1 | EEIAKLYKQLDDKDEEINQQsQLVEKLKTQMLDQEELLAST |
| P34896 | S381 | Sugiyama | SHMT1 | VDLRSKGTDGGRAEKVLEACsIACNKNTCPGDRSALRPSGL |
| P34897 | S417 | Sugiyama | SHMT2 | ERVLELVSITANKNTCPGDRsAItPGGLRLGAPALtSRQFR |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34931 | T228 | Sugiyama | HSPA1L | DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK |
| P34931 | T47 | Sugiyama | HSPA1L | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN |
| P35221 | S295 | Sugiyama | CTNNA1 | GGELAyALNNFDKQIIVDPLsFsEERFRPSLEERLESIISG |
| P35579 | S169 | Sugiyama | MYH9 | HIyAITDtAyRSMMQDREDQsILCTGESGAGKTENTKKVIQ |
| P35579 | S1713 | Sugiyama | MYH9 | ERAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQ |
| P35579 | S1714 | Sugiyama | MYH9 | RAKRQAQQERDELADEIANssGKGALALEEKRRLEARIAQL |
| P35579 | T1208 | Sugiyama | MYH9 | QEMRQKHsQAVEELAEQLEQtKRVKANLEKAKQtLENERGE |
| P35606 | T357 | Sugiyama | COPB2 | DGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVCGDGEYII |
| P35613 | S277 | Sugiyama | BSG UNQ6505/PRO21383 | KITDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPG |
| P35637 | S360 | Sugiyama | FUS TLS | sFDDPPsAKAAIDWFDGKEFsGNPIKVsFATRRADFNRGGG |
| P35998 | S89 | Sugiyama | PSMC2 MSS1 | DTGLAPPALWDLAADKQTLQsEQPLQVARCTKIINADSEDP |
| P36578 | S63 | Sugiyama | RPL4 RPL1 | NLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGG |
| P36578 | S66 | Sugiyama | RPL4 RPL1 | KNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGGGtHR |
| P36578 | T62 | Sugiyama | RPL4 RPL1 | TNLRKNNRQPyAVsELAGHQtsAEsWGtGRAVARIPRVRGG |
| P36871 | S483 | Sugiyama | PGM1 | DKVYtVEKADNFEysDPVDGsIsRNQGLRLIFTDGSRIVFR |
| P37802 | S163 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG |
| P37802 | T180 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_ |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P38646 | T120 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV |
| P38646 | T480 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | RNTTIPTKKSQVFstAADGQtQVEIKVCQGEREMAGDNKLL |
| P38646 | T87 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKR |
| P38646 | Y118 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK |
| P39019 | S93 | Sugiyama | RPS19 | GsMTKIYGGRQRNGVMPsHFsRGsKsVARRVLQALEGLKMV |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P39748 | S293 | Sugiyama | FEN1 RAD2 | NWLHKEAHQLFLEPEVLDPEsVELKWSEPNEEELIKFMCGE |
| P42166 | T160 | Sugiyama | TMPO LAP2 | KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs |
| P42167 | T160 | Sugiyama | TMPO LAP2 | KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS |
| P42677 | S78 | Sugiyama | RPS27 MPS1 | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| P43034 | S152 | Sugiyama | PAFAH1B1 LIS1 MDCR MDS PAFAHA | IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM |
| P43243 | S188 | Sugiyama | MATR3 KIAA0723 | EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P45985 | S257 | SIGNOR|EPSD|PSP | MAP2K4 JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1 | LDRSGNIKLCDFGIsGQLVDsIAKtRDAGCRPyMAPERIDP |
| P45985 | T261 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | MAP2K4 JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1 | GNIKLCDFGIsGQLVDsIAKtRDAGCRPyMAPERIDPSASR |
| P46060 | S24 | Sugiyama | RANGAP1 KIAA1835 SD | EDIAKLAETLAKTQVAGGQLsFKGKSLKLNTAEDAKDVIKE |
| P46734 | S218 | EPSD|PSP | MAP2K3 MEK3 MKK3 PRKMK3 SKK2 | INKEGHVKMCDFGISGyLVDsVAKtMDAGCKPYMAPERINP |
| P46734 | T222 | EPSD|PSP | MAP2K3 MEK3 MKK3 PRKMK3 SKK2 | GHVKMCDFGISGyLVDsVAKtMDAGCKPYMAPERINPELNQ |
| P46777 | S172 | Sugiyama | RPL5 MSTP030 | RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA |
| P46777 | S176 | Sugiyama | RPL5 MSTP030 | GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46777 | T177 | Sugiyama | RPL5 MSTP030 | NKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHRK |
| P47712 | S458 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | DDEsHEPKGtENEDAGsDyQsDNQASWIHRMIMALVSDSAL |
| P47712 | S724 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | NIDVIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFL |
| P47712 | S727 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP |
| P47712 | T425 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | LGVSGSQsRGstMEEELENIttKHIVsNDssDsDDEsHEPK |
| P47756 | S204 | Sugiyama | CAPZB | sGtMNLGGsLtRQMEKDEtVsDCsPHIANIGRLVEDMENKI |
| P47756 | S90 | Sugiyama | CAPZB | SyRsPWSNKyDPPLEDGAMPsARLRKLEVEANNAFDQYRDL |
| P48739 | S165 | Sugiyama | PITPNB | DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP |
| P48739 | T168 | Sugiyama | PITPNB | QVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsPDCP |
| P48741 | T228 | Sugiyama | HSPA7 HSP70B | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P48741 | T47 | Sugiyama | HSPA7 HSP70B | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P49321 | S659 | Sugiyama | NASP | IEELKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsst |
| P49327 | S1129 | Sugiyama | FASN FAS | QQVPILEKFCFtPHTEEGCLsERAALQEELQLCKGLVQALQ |
| P49327 | T309 | Sugiyama | FASN FAS | yIEAHGtGTKVGDPQELNGItRALCAtRQEPLLIGsTKSNM |
| P49588 | S188 | Sugiyama | AARS1 AARS | PGNMKDNFWEMGDtGPCGPCsEIHyDRIGGRDAAHLVNQDD |
| P49589 | S305 | Sugiyama | CARS1 CARS | KLVPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKA |
| P49736 | S170 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | KRRQVERAtEDGEEDEEMIEsIENLEDLKGHSVREWVsMAG |
| P49792 | S14 | Sugiyama | RANBP2 NUP358 | _______MRRSKADVERyIAsVQGstPsPRQKSMKGFYFAK |
| P49792 | S1456 | Sugiyama | RANBP2 NUP358 | IACQNTKsANKsGssFVHQAsFKFGQGDLPKPINSDFRSVF |
| P49792 | S1765 | Sugiyama | RANBP2 NUP358 | IACQCPSKQNQtTAIstPAssEIsKAPKsGFEGMFIRKGQW |
| P49792 | S1768 | Sugiyama | RANBP2 NUP358 | QCPSKQNQtTAIstPAssEIsKAPKsGFEGMFIRKGQWDCS |
| P50395 | S316 | Sugiyama | GDI2 RABGDIB | QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM |
| P50395 | S43 | Sugiyama | GDI2 RABGDIB | MSVNGKKVLHMDRNPyyGGEsAsItPLEDLyKRFKIPGsPP |
| P50395 | T413 | Sugiyama | GDI2 RABGDIB | GtEsQIFIsRTyDAttHFEttCDDIKNIYKRMtGsEFDFEE |
| P50416 | S747 | Sugiyama | CPT1A CPT1 | VGENLINFHISSKFSCPETDsHRFGRHLKEAMTDIITLFGL |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50914 | T43 | Sugiyama | RPL14 | KLVAIVDVIDQNRALVDGPCtQVRRQAMPFKCMQLTDFILK |
| P50990 | S161 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | EILPNLVCCsAKNLRDIDEVssLLRTSIMSKQyGNEVFLAK |
| P50990 | T286 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | MNFsKGEENLMDAQVKAIADtGANVVVtGGKVADMALHYAN |
| P50995 | S490 | Sugiyama | ANXA11 ANX11 | RSEYKRMYGKsLyHDISGDtsGDyRKILLKICGGND_____ |
| P51991 | S375 | Sugiyama | HNRNPA3 HNRPA3 | ssGsPyGGGyGsGGGsGGyGsRRF_________________ |
| P52597 | S107 | Sugiyama | HNRNPF HNRPF | KSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTKEEI |
| P52907 | S219 | Sugiyama | CAPZA1 | YEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAENEy |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P54652 | S224 | Sugiyama | HSPA2 | GGGTFDVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHL |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P54652 | T46 | Sugiyama | HSPA2 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN |
| P55036 | S266 | Sugiyama | PSMD4 MCB1 | AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ |
| P55060 | T339 | Sugiyama | CSE1L CAS XPO2 | QFLASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADE |
| P55060 | T341 | Sugiyama | CSE1L CAS XPO2 | LASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEA |
| P55084 | S248 | Sugiyama | HADHB MSTP029 | DRLAAAFAVSRLEQDEyALRsHSLAKKAQDEGLLSDVVPFK |
| P55209 | T62 | Sugiyama | NAP1L1 NRP | MMQNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALK |
| P55209 | T64 | Sugiyama | NAP1L1 NRP | QNPQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNL |
| P55795 | S104 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | EVFKSNsVEMDWVLKHtGPNsPDtANDGFVRLRGLPFGCSK |
| P55884 | S185 | Sugiyama | EIF3B EIF3S9 | EEELLGDVLKDRPQEADGIDsVIVVDNVPQVGPDRLEKLKN |
| P56192 | S812 | Sugiyama | MARS1 MARS | GHQIGTVSPLFQKLENDQIEsLRQRFGGGQAKtsPKPAVVE |
| P56537 | T91 | Sugiyama | EIF6 EIF3A ITGB4BP OK/SW-cl.27 | LVPNNTTDQELQHIRNSLPDtVQIRRVEERLSALGNVTTCN |
| P57721 | S173 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | KEIREstGAQVQVAGDMLPNstERAVTISGTPDAIIQCVKQ |
| P57721 | S82 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK |
| P57721 | T174 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | EIREstGAQVQVAGDMLPNstERAVTISGTPDAIIQCVKQI |
| P60174 | S204 | Sugiyama | TPI1 TPI | EVHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQ |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | S97 | Sugiyama | TPI1 TPI | GEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELIGQKVAHA |
| P60174 | T205 | Sugiyama | TPI1 TPI | VHEKLRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQP |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60660 | T44 | Sugiyama | MYL6 | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDEMNVKV |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S239 | Sugiyama | ACTB | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | S60 | Sugiyama | ACTB | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P60709 | Y53 | Sugiyama | ACTB | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P60842 | S189 | Sugiyama | EIF4A1 DDX2A EIF4A | RYLSPKYIKMFVLDEADEMLsRGFKDQIyDIFQKLNsNtQV |
| P60891 | S10 | Sugiyama | PRPS1 | ___________MPNIKIFsGssHQDLSQKIADRLGLELGKV |
| P60900 | S177 | Sugiyama | PSMA6 PROS27 | AGyyCGFKATAAGVKQtEstsFLEKKVKKKFDWTFEQTVET |
| P61204 | S147 | Sugiyama | ARF3 | KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY |
| P61247 | S237 | Sugiyama | RPS3A FTE1 MFTL | MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE |
| P61247 | S238 | Sugiyama | RPS3A FTE1 MFTL | LKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyEP |
| P61604 | S64 | Sugiyama | HSPE1 | AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD |
| P61978 | S36 | Sugiyama | HNRNPK HNRPK | NGEFGKRPAEDMEEEQAFKRsRNtDEMVELRILLQSKNAGA |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61978 | S81 | Sugiyama | HNRNPK HNRPK | GGKNIKALRtDyNAsVsVPDssGPERILsISADIETIGEIL |
| P62191 | T56 | Sugiyama | PSMC1 | KKKKTKGPDAASKLPLVtPHtQCRLKLLKLERIKDYLLMEE |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62263 | S137 | Sugiyama | RPS14 PRO2640 | RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______ |
| P62277 | S12 | Sugiyama | RPS13 | _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD |
| P62316 | S30 | Sugiyama | SNRPD2 SNRPD1 | EMtPEELQKREEEEFNtGPLsVLtQsVKNNtQVLINCRNNK |
| P62316 | S35 | Sugiyama | SNRPD2 SNRPD1 | ELQKREEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGR |
| P62316 | T40 | Sugiyama | SNRPD2 SNRPD1 | EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD |
| P62424 | T84 | Sugiyama | RPL7A SURF-3 SURF3 | QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP |
| P62736 | S241 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | S62 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62736 | Y55 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P62857 | S41 | Sugiyama | RPS28 | tGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLLEs |
| P62942 | S9 | Sugiyama | FKBP1A FKBP1 FKBP12 | ____________MGVQVEtIsPGDGRtFPKRGQtCVVHytG |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | S37 | Sugiyama | YWHAZ | ERyDDMAACMKsVtEQGAELsNEERNLLsVAyKNVVGARRs |
| P63151 | S412 | Sugiyama | PPP2R2A | LKPRKVCASGKRKKDEIsVDsLDFNKKILHTAWHPKENIIA |
| P63167 | S21 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAH |
| P63167 | T26 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF |
| P63173 | T14 | Sugiyama | RPL38 | _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF |
| P63220 | S68 | Sugiyama | RPS21 | GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____ |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S239 | Sugiyama | ACTG1 ACTG | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | S60 | Sugiyama | ACTG1 ACTG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63261 | Y53 | Sugiyama | ACTG1 ACTG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P63267 | S240 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | S61 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P63267 | Y54 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68032 | S241 | Sugiyama | ACTC1 ACTC | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | S62 | Sugiyama | ACTC1 ACTC | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68032 | Y55 | Sugiyama | ACTC1 ACTC | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68104 | T24 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | EKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEK |
| P68133 | S241 | Sugiyama | ACTA1 ACTA | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | S62 | Sugiyama | ACTA1 ACTA | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68133 | Y55 | Sugiyama | ACTA1 ACTA | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | S54 | Sugiyama | TUBA1B | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P68363 | T51 | Sugiyama | TUBA1B | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P68363 | T56 | Sugiyama | TUBA1B | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T80 | Sugiyama | TUBA1B | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| P68363 | T82 | Sugiyama | TUBA1B | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| P78417 | S23 | Sugiyama | GSTO1 GSTTLP28 | GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK |
| P80303 | S96 | Sugiyama | NUCB2 NEFA | QKADIEEIKSGRLsKELDLVsHHVRTKLDELKRQEVGRLRM |
| P84077 | S147 | Sugiyama | ARF1 | KQDLPNAMNAAEITDKLGLHsLRHRNWYIQATCATSGDGLY |
| P84098 | S37 | Sugiyama | RPL19 | CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV |
| P84098 | T29 | Sugiyama | RPL19 | RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL |
| P98082 | T638 | Sugiyama | DAB2 DOC2 | TPPQPPPRAGPPKDIssDAFtALDPLGDKEIKDVKEMFKDF |
| P99999 | S48 | Sugiyama | CYCS CYC | KTGPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEY |
| Q00610 | S886 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01082 | S2197 | Sugiyama | SPTBN1 SPTB2 | KTALPAQsAAtLPARtQEtPsAQMEGFLNRKHEWEAHNKKA |
| Q01082 | T1386 | Sugiyama | SPTBN1 SPTB2 | ESTTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSD |
| Q01105 | S133 | Sugiyama | SET | DEEALHYLTRVEVtEFEDIKsGyRIDFyFDENPyFENKVLS |
| Q01105 | S165 | Sugiyama | SET | PyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQ |
| Q01105 | S166 | Sugiyama | SET | yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q01105 | S63 | Sugiyama | SET | EAIEHIDEVQNEIDRLNEQAsEEILKVEQKYNKLRQPFFQK |
| Q02543 | T107 | Sugiyama | RPL18A | RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM |
| Q02818 | S93 | Sugiyama | NUCB1 NUC | QAANAEDIKSGKLsRELDFVsHHVRTKLDELKRQEVSRLRM |
| Q04837 | S79 | Sugiyama | SSBP1 SSBP | LATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPGLRDVAy |
| Q04917 | S38 | Sugiyama | YWHAH YWHA1 | ERyDDMAsAMKAVtELNEPLsNEDRNLLsVAyKNVVGARRS |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q05639 | T24 | Sugiyama | EEF1A2 EEF1AL STN | EKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEK |
| Q05682 | T167 | Sugiyama | CALD1 CAD CDM | TEKEEKsESRQERyEIEETEtVtKSYQKNDWRDAEENKKED |
| Q05682 | T169 | Sugiyama | CALD1 CAD CDM | KEEKsESRQERyEIEETEtVtKSYQKNDWRDAEENKKEDKE |
| Q06830 | S126 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | SDPKRtIAQDyGVLKADEGIsFRGLFIIDDKGILRQItVND |
| Q07021 | S205 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | DCHyPEDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYT |
| Q07021 | S210 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS |
| Q07021 | T165 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | GEEEPSQGQKVEEQEPELtstPNFVVEVIKNDDGKKALVLD |
| Q07157 | S1071 | Sugiyama | TJP1 ZO1 | sRDLEQPtyRyEsssytDQFsRNYEHRLRYEDRVPMyEEQW |
| Q07666 | S150 | Sugiyama | KHDRBS1 SAM68 | EKIQKGDSKKDDEENyLDLFsHKNMKLKERVLIPVKQYPKF |
| Q08J23 | S383 | Sugiyama | NSUN2 SAKI TRM4 | QWKVMTKDGQWFTDWDAVPHsRHTQIRPTMFPPKDPEKLQA |
| Q09028 | S146 | Sugiyama | RBBP4 RBAP48 | EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE |
| Q12874 | S76 | Sugiyama | SF3A3 SAP61 | NLRDLyDDKDGLRKEELNAIsGPNEFAEFyNRLKQIKEFHR |
| Q12906 | S317 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | KEAtDAIGHLDRQQREDItQsAQHALRLAAFGQLHKVLGMD |
| Q12906 | S36 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | AKHssVyPTQEELEAVQNMVsHtERALKAVsDWIDEQEKGs |
| Q12906 | T315 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | CEKEAtDAIGHLDRQQREDItQsAQHALRLAAFGQLHKVLG |
| Q12906 | Y22 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | RPMRIFVNDDRHVMAKHssVyPTQEELEAVQNMVsHtERAL |
| Q13131 | T183 | EPSD|PSP | PRKAA1 AMPK1 | NAKIADFGLsNMMsDGEFLRtsCGsPNyAAPEVISGRLYAG |
| Q13153 | S133 | GPS6|PSP | PAK1 | TKsEQKKNPQAVLDVLEFYNsKKTSNSQKYMsFtDKsAEDy |
| Q13153 | S204 | GPS6|PSP | PAK1 | AtPPPVIAPRPEHTKsVytRsVIEPLPVtPtRDVAtsPIsP |
| Q13263 | S784 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK |
| Q13283 | S67 | Sugiyama | G3BP1 G3BP | sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN |
| Q13283 | T241 | Sugiyama | G3BP1 G3BP | ETAPEDAQKsssPAPADIAQtVQEDLRtFsWAsVtsKNLPP |
| Q13409 | S111 | Sugiyama | DYNC1I2 DNCI2 DNCIC2 | KsVStPsEAGsQDsGDGAVGsRTLHWDTDPSVLQLHSDSDL |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13509 | T107 | Sugiyama | TUBB3 TUBB4 | PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC |
| Q13526 | S115 | Sugiyama | PIN1 | KIKSGEEDFEsLAsQFSDCSsAKARGDLGAFsRGQMQKPFE |
| Q13526 | S138 | SIGNOR|EPSD|PSP | PIN1 | ARGDLGAFsRGQMQKPFEDAsFALRTGEMSGPVFTDsGIHI |
| Q13769 | S312 | Sugiyama | THOC5 C22orf19 KIAA0983 | GSVDEAKALFKPPEDsQDDEsDsDAEEEQttKRRRPtLGVQ |
| Q13769 | S314 | Sugiyama | THOC5 C22orf19 KIAA0983 | VDEAKALFKPPEDsQDDEsDsDAEEEQttKRRRPtLGVQLD |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q13885 | T107 | Sugiyama | TUBB2A TUBB2 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q14152 | S227 | Sugiyama | EIF3A EIF3S10 KIAA0139 | QIQRHHNQstAINLNNPESQsMHLETRLVQLDSAISMELWQ |
| Q14152 | S513 | Sugiyama | EIF3A EIF3S10 KIAA0139 | FGsDLNyAtREDAPIGPHLQsMPSEQIRNQLTAMSSVLAKA |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14152 | T1378 | Sugiyama | EIF3A EIF3S10 KIAA0139 | AEKDREsLRRTKNEtDEDGWttVRR________________ |
| Q14152 | T1379 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EKDREsLRRTKNEtDEDGWttVRR_________________ |
| Q14152 | T216 | Sugiyama | EIF3A EIF3S10 KIAA0139 | KLCDNLRMHLsQIQRHHNQstAINLNNPESQsMHLETRLVQ |
| Q14157 | S859 | Sugiyama | UBAP2L KIAA0144 NICE4 | FPtPttPLtGRDGsLAsNPysGDLtKFGRGDASSPAPATTL |
| Q14204 | S247 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | PKVTDFGDKVEDPTFLNQLQsGVNRWIREIQKVTKLDRDPA |
| Q14240 | S190 | Sugiyama | EIF4A2 DDX2B EIF4F | RYLSPKWIKMFVLDEADEMLsRGFKDQIYEIFQKLNTSIQV |
| Q14247 | S117 | Sugiyama | CTTN EMS1 | KsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVDQsAV |
| Q14247 | S331 | Sugiyama | CTTN EMS1 | GVQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIR |
| Q14247 | S332 | Sugiyama | CTTN EMS1 | VQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIRA |
| Q14247 | T344 | Sugiyama | CTTN EMS1 | FEDVtQVssAyQKTVPVEAVtsKtsNIRANFENLAKEKEQE |
| Q14247 | T347 | Sugiyama | CTTN EMS1 | VtQVssAyQKTVPVEAVtsKtsNIRANFENLAKEKEQEDRR |
| Q14498 | S336 | Sugiyama | RBM39 HCC1 RNPC2 | LAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGR |
| Q14568 | S165 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK |
| Q14568 | S169 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | TVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILH |
| Q14568 | S50 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14677 | S166 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | REERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKWDE |
| Q14677 | T271 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | KDEEETVTTKHIHItQATEttttRHKRTANPsKtIDLGAAA |
| Q14683 | S962 | Sugiyama | SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 | LSKGtMDDIsQEEGssQGEDsVsGsQRIssIYAREALIEID |
| Q15056 | S14 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | _______MADFDtyDDRAyssFGGGRGsRGsAGGHGsRSQK |
| Q15084 | S389 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | FALLKGsFsEQGINEFLRELsFGRGstAPVGGGAFPtIVER |
| Q15165 | S300 | Sugiyama | PON2 | WVGCHPNGQKLFVYDPNNPPsSEVLRIQNILSEKPTVTTVY |
| Q15181 | S127 | Sugiyama | PPA1 IOPPP PP | NDKHTGCCGDNDPIDVCEIGsKVCARGEIIGVKVLGILAMI |
| Q15293 | T100 | Sugiyama | RCN1 RCN | sKERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNV |
| Q15293 | T101 | Sugiyama | RCN1 RCN | KERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNVA |
| Q15365 | S141 | Sugiyama | PCBP1 | KEIREstGAQVQVAGDMLPNstERAITIAGVPQSVTECVKQ |
| Q15365 | S50 | Sugiyama | PCBP1 | GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK |
| Q15365 | T142 | Sugiyama | PCBP1 | EIREstGAQVQVAGDMLPNstERAITIAGVPQSVTECVKQI |
| Q15366 | S141 | Sugiyama | PCBP2 | KEIREstGAQVQVAGDMLPNstERAITIAGIPQSIIECVKQ |
| Q15366 | S50 | Sugiyama | PCBP2 | GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK |
| Q15366 | T142 | Sugiyama | PCBP2 | EIREstGAQVQVAGDMLPNstERAITIAGIPQSIIECVKQI |
| Q16401 | S98 | Sugiyama | PSMD5 KIAA0072 | VHVARNLRVDLQRGLIHPDDsVKILTLSQIGRIVENSDAVT |
| Q16531 | S379 | Sugiyama | DDB1 XAP1 | IVDMCVVDLERQGQGQLVTCsGAFKEGSLRIIRNGIGIHEH |
| Q16576 | S145 | Sugiyama | RBBP7 RBAP46 | EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE |
| Q16584 | S155 | Sugiyama | MAP3K11 MLK3 PTK1 SPRK | SWRGELVAVKAARQDPDEDIsVTAEsVRQEARLFAMLAHPN |
| Q16584 | S160 | Sugiyama | MAP3K11 MLK3 PTK1 SPRK | LVAVKAARQDPDEDIsVTAEsVRQEARLFAMLAHPNIIALK |
| Q16584 | S281 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | MAP3K11 MLK3 PTK1 SPRK | KTLKITDFGLAREWHKtTQMsAAGTYAWMAPEVIKASTFSK |
| Q16584 | T277 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | MAP3K11 MLK3 PTK1 SPRK | DMEHKTLKITDFGLAREWHKtTQMsAAGTYAWMAPEVIKAS |
| Q16658 | T239 | Sugiyama | FSCN1 FAN1 HSN SNL | GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs |
| Q16775 | T292 | Sugiyama | HAGH GLO2 HAGH1 | FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____ |
| Q16881 | T522 | Sugiyama | TXNRD1 GRIM12 KDRF | LLAQRLYAGSTVKCDyENVPttVFTPLEyGACGLSEEKAVE |
| Q16881 | T523 | Sugiyama | TXNRD1 GRIM12 KDRF | LAQRLYAGSTVKCDyENVPttVFTPLEyGACGLSEEKAVEK |
| Q32P51 | S95 | Sugiyama | HNRNPA1L2 HNRNPA1L | TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| Q4V328 | S666 | Sugiyama | GRIPAP1 KIAA1167 | EELVLsEMNsPSRtQtGDsssIssFsYREILREKEssAVPA |
| Q562R1 | S240 | Sugiyama | ACTBL2 | VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE |
| Q562R1 | T107 | Sugiyama | ACTBL2 | WYHTFYNELRVAPDEHPILLtEAPLNPKINREKMTQIMFEA |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q58FF6 | T165 | Sugiyama | HSP90AB4P | DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | S408 | Sugiyama | HSP90AB3P HSP90BC | EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| Q58FF7 | S67 | Sugiyama | HSP90AB3P HSP90BC | ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERTLALV |
| Q58FF7 | T169 | Sugiyama | HSP90AB3P HSP90BC | DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG |
| Q58FF8 | S308 | Sugiyama | HSP90AB2P HSP90BB | YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE |
| Q58FF8 | S67 | Sugiyama | HSP90AB2P HSP90BB | ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQEHTLTLV |
| Q5H9R7 | S579 | Sugiyama | PPP6R3 C11orf23 KIAA1558 PP6R3 SAPL SAPS3 | IDQFGFNDEKFADQDDIGNVsFDRVSDINFTLNTNESGNIA |
| Q5VTE0 | T24 | Sugiyama | EEF1A1P5 EEF1AL3 | EKtHINIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEK |
| Q66LE6 | S418 | Sugiyama | PPP2R2D KIAA1541 | LKPRKVCTGGKRRKDEIsVDsLDFNKKILHTAWHPVDNVIA |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | S54 | Sugiyama | TUBA3E | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q6PEY2 | T51 | Sugiyama | TUBA3E | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q6PEY2 | T56 | Sugiyama | TUBA3E | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | S939 | Sugiyama | POTEE A26C1A POTE2 | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6UN15 | S492 | Sugiyama | FIP1L1 FIP1 RHE | DRDRDRERERTRERERERDHsPtPsVFNsDEERyRYREYAE |
| Q6UN15 | S496 | Sugiyama | FIP1L1 FIP1 RHE | DRERERTRERERERDHsPtPsVFNsDEERyRYREYAERGYE |
| Q6UN15 | T494 | Sugiyama | FIP1L1 FIP1 RHE | DRDRERERTRERERERDHsPtPsVFNsDEERyRYREYAERG |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | S54 | Sugiyama | TUBA1A TUBA3 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q71U36 | T51 | Sugiyama | TUBA1A TUBA3 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q71U36 | T56 | Sugiyama | TUBA1A TUBA3 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T80 | Sugiyama | TUBA1A TUBA3 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q71U36 | T82 | Sugiyama | TUBA1A TUBA3 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q71UM5 | S78 | Sugiyama | RPS27L | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| Q7Z417 | S121 | Sugiyama | NUFIP2 KIAA1321 PIG1 | AGEREISLKNLssDEAtNPIsRVLNGNQQVVDTsLKQTVKA |
| Q8N684 | T203 | Sugiyama | CPSF7 | GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP |
| Q8NBS9 | S129 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | MEDAKVYVAKVDCtAHsDVCsAQGVRGYPTLKLFKPGQEAV |
| Q8NBS9 | S255 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | EHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDGKKVD |
| Q8NHW5 | S307 | Sugiyama | RPLP0P6 | AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________ |
| Q92945 | S200 | Sugiyama | KHSRP FUBP2 | IsPDsGGLPERsVsLtGAPEsVQKAKMMLDDIVSRGRGGPP |
| Q92973 | S339 | Sugiyama | TNPO1 KPNB2 MIP1 TRN | SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE |
| Q96AE4 | S52 | Sugiyama | FUBP1 | KDALQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQ |
| Q96AE4 | S55 | Sugiyama | FUBP1 | LQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQPDA |
| Q96B36 | S211 | Sugiyama | AKT1S1 PRAS40 | WGFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAE |
| Q96GM8 | S420 | Sugiyama | TOE1 | KNDLEMGIKAARPEIADRATsEVPGsQAsPNPVPGDGLHRA |
| Q96HE7 | T148 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA |
| Q96QK1 | S760 | Sugiyama | VPS35 MEM3 TCCCTA00141 | IQVLNQLIQKIREDLPNLEssEEtEQINKHFHNtLEHLRLR |
| Q96RE7 | S330 | Sugiyama | NACC1 BTBD14B NAC1 | MNVGQTAEKVEALPEQVAPEsRNRIRVRQDLASLPAELINQ |
| Q96RS6 | S373 | Sugiyama | NUDCD1 CML66 | EGLTWPELVIGDKQGELIRDsAQCAAIAERLMHLtsEELNP |
| Q99426 | T120 | Sugiyama | TBCB CG22 CKAP1 | DVSRVEKytIsQEAyDQRQDtVRSFLKRsKLGRyNEEERAQ |
| Q99832 | T300 | Sugiyama | CCT7 CCTH NIP7-1 | KIHHSGAKVVLSKLPIGDVAtQyFADRDMFCAGRVPEEDLK |
| Q99832 | T351 | Sugiyama | CCT7 CCTH NIP7-1 | QtSVNALSADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCt |
| Q99832 | T385 | Sugiyama | CCT7 CCTH NIP7-1 | PKAKTCtFILRGGAEQFMEEtERSLHDAIMIVRRAIKNDSV |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | S54 | Sugiyama | TUBA1C TUBA6 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q9BQE3 | T51 | Sugiyama | TUBA1C TUBA6 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q9BQE3 | T56 | Sugiyama | TUBA1C TUBA6 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T80 | Sugiyama | TUBA1C TUBA6 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q9BQE3 | T82 | Sugiyama | TUBA1C TUBA6 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q9BRK5 | S99 | Sugiyama | SDF4 CAB45 PSEC0034 | QEVFLGKDLGGFDEDAEPRRsRRKLMVIFSKVDVNTDRKIS |
| Q9BV86 | S181 | Sugiyama | NTMT1 C9orf32 METTL11A NRMT NRMT1 AD-003 | GIIVIKDNMAQEGVILDDVDsSVCRDLDVVRRIICSAGLSL |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BVA1 | T107 | Sugiyama | TUBB2B | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q9BWD1 | S208 | Sugiyama | ACAT2 ACTL | RTENAQKAGHFDKEIVPVLVstRKGLIEVKtDEFPRHGsNI |
| Q9BXP5 | T705 | Sugiyama | SRRT ARS2 ASR2 | AQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKFKGP |
| Q9BYX7 | S239 | Sugiyama | POTEKP ACTBL3 FKSG30 | VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9H1A4 | S355 | Sugiyama | ANAPC1 TSG24 | PsLHsRsPsISNMAALsRAHsPALGVHsFsGVQRFNIssHN |
| Q9H1A4 | S364 | Sugiyama | ANAPC1 TSG24 | ISNMAALsRAHsPALGVHsFsGVQRFNIssHNQsPKRHSIS |
| Q9H2U2 | S313 | Sugiyama | PPA2 HSPC124 | VQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLG |
| Q9H7N4 | S498 | Sugiyama | SCAF1 SFRS19 SRA1 | GGLDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKK |
| Q9H7N4 | S500 | Sugiyama | SCAF1 SFRS19 SRA1 | LDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKKSR |
| Q9NWU1 | S108 | Sugiyama | OXSM | VAAYVPRGSDEGQFNEQNFVsKSDIKSMSSPTIMAIGAAEL |
| Q9NY33 | S190 | Sugiyama | DPP3 | TYFSGNCTMEDAKLAQDFLDsQNLsAyNtRLFKEVDGEGKP |
| Q9NY33 | S194 | Sugiyama | DPP3 | GNCTMEDAKLAQDFLDsQNLsAyNtRLFKEVDGEGKPYYEV |
| Q9NZB2 | S16 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | _____MGVQGFQDyIEKHCPsAVVPVELQKLARGsLVGGGR |
| Q9UBQ7 | S260 | Sugiyama | GRHPR GLXR MSTP035 | FINISRGDVVNQDDLyQALAsGKIAAAGLDVtsPEPLPTNH |
| Q9UBR2 | S78 | Sugiyama | CTSZ | SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST |
| Q9UH65 | S409 | Sugiyama | SWAP70 KIAA0640 HSPC321 | TELEREKLIRQQMEEQVAQKsSELEQYLQRVRELEDMyLKL |
| Q9UII2 | S39 | Sugiyama | ATP5IF1 ATPI ATPIF1 | TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF |
| Q9UJW0 | T141 | Sugiyama | DCTN4 | VGMADKSVASGGWQEPENPHtQRMNKLIEyyQQLAQKEKVE |
| Q9UMX5 | T130 | Sugiyama | NENF CIR2 SPUF | LTHDTTGLTAKELEALDEVFtKVYKAKYPIVGYTARRILNE |
| Q9UNZ2 | S176 | Sugiyama | NSFL1C UBXN2C | RLGAAPEEEsAyVAGEKRQHssQDVHVVLKLWKsGFsLDNG |
| Q9Y262 | S414 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | YGDKMLRMQKGDPQVyEELFsysCPKFLSPVVPNYDNVHPN |
| Q9Y2B0 | S63 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2B0 | T79 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | NPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGEQIDPs |
| Q9Y2L1 | S223 | Sugiyama | DIS3 KIAA1008 RRP44 | ANPELIDRLACLsEEGNEIEsGKIIFSEHLPLSKLQQGIKS |
| Q9Y450 | S67 | Sugiyama | HBS1L HBS1 KIAA1038 | KPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCLDH |
| Q9Y4H2 | S30 | Sugiyama | IRS2 | PGPASGDGPNLNNNNNNNNHsVRKCGYLRKQKHGHKRFFVL |
| Q9Y696 | S31 | Sugiyama | CLIC4 | KEEDKEPLIELFVKAGsDGEsIGNCPFSQRLFMILWLKGVV |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle | R-HSA-1640170 | 3.330669e-16 | 15.477 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 3.219647e-15 | 14.492 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 2.342793e-12 | 11.630 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 4.533041e-12 | 11.344 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 4.101508e-11 | 10.387 | 0 | 0 |
| M Phase | R-HSA-68886 | 4.452128e-11 | 10.351 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 5.428091e-11 | 10.265 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 6.561962e-11 | 10.183 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 7.530713e-10 | 9.123 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 8.045244e-10 | 9.094 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 1.013053e-09 | 8.994 | 1 | 0 |
| Nervous system development | R-HSA-9675108 | 1.236009e-09 | 8.908 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 7.419729e-09 | 8.130 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 9.834106e-09 | 8.007 | 1 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.391005e-08 | 7.857 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 6.470691e-08 | 7.189 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 6.470691e-08 | 7.189 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 7.001546e-08 | 7.155 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.090235e-07 | 6.962 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 1.136542e-07 | 6.944 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.437430e-07 | 6.842 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.615297e-07 | 6.792 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.615297e-07 | 6.792 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 2.026781e-07 | 6.693 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.901747e-07 | 6.537 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.034657e-06 | 5.985 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 1.294653e-06 | 5.888 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.368871e-06 | 5.864 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.769264e-06 | 5.752 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.971876e-06 | 5.705 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.939279e-06 | 5.532 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 2.939279e-06 | 5.532 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 3.039342e-06 | 5.517 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 3.538727e-06 | 5.451 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 3.895957e-06 | 5.409 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 5.630815e-06 | 5.249 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 6.799867e-06 | 5.167 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.229755e-05 | 4.910 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.400478e-05 | 4.854 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 1.433835e-05 | 4.844 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.522610e-05 | 4.817 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.560624e-05 | 4.807 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 2.467150e-05 | 4.608 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 2.820572e-05 | 4.550 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 3.332772e-05 | 4.477 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 3.669252e-05 | 4.435 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 3.669941e-05 | 4.435 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 3.834689e-05 | 4.416 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 3.922393e-05 | 4.406 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 4.374287e-05 | 4.359 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 5.437913e-05 | 4.265 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 6.483198e-05 | 4.188 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 6.789113e-05 | 4.168 | 0 | 0 |
| Kinesins | R-HSA-983189 | 6.604585e-05 | 4.180 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 6.665472e-05 | 4.176 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 6.665472e-05 | 4.176 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 7.258845e-05 | 4.139 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 8.418820e-05 | 4.075 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 8.752803e-05 | 4.058 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 8.465673e-05 | 4.072 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 8.752880e-05 | 4.058 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 9.839529e-05 | 4.007 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 9.982941e-05 | 4.001 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 1.143951e-04 | 3.942 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 1.146260e-04 | 3.941 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.146260e-04 | 3.941 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.146260e-04 | 3.941 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.151985e-04 | 3.939 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.169303e-04 | 3.932 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 1.162406e-04 | 3.935 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.252298e-04 | 3.902 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.277919e-04 | 3.893 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 1.498146e-04 | 3.824 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 1.515400e-04 | 3.819 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.515400e-04 | 3.819 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.527092e-04 | 3.816 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.546508e-04 | 3.811 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.695813e-04 | 3.771 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.863227e-04 | 3.730 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 2.053541e-04 | 3.687 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.959016e-04 | 3.708 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 2.629839e-04 | 3.580 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.705209e-04 | 3.568 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 3.159019e-04 | 3.500 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 3.466124e-04 | 3.460 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 3.515489e-04 | 3.454 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 3.591206e-04 | 3.445 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 4.187246e-04 | 3.378 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.591021e-04 | 3.338 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 5.192389e-04 | 3.285 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 5.737484e-04 | 3.241 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 5.835428e-04 | 3.234 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 6.140440e-04 | 3.212 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 6.170831e-04 | 3.210 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 6.621841e-04 | 3.179 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 6.452115e-04 | 3.190 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 6.342231e-04 | 3.198 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 6.550489e-04 | 3.184 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 7.127822e-04 | 3.147 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 7.648675e-04 | 3.116 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 8.266329e-04 | 3.083 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 8.131831e-04 | 3.090 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 8.472691e-04 | 3.072 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 8.525645e-04 | 3.069 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 8.746986e-04 | 3.058 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 9.225832e-04 | 3.035 | 1 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.112069e-03 | 2.954 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.120382e-03 | 2.951 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.141753e-03 | 2.942 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.143598e-03 | 2.942 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.265874e-03 | 2.898 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 1.269443e-03 | 2.896 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.441735e-03 | 2.841 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.441735e-03 | 2.841 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.494482e-03 | 2.826 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 1.500839e-03 | 2.824 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.782000e-03 | 2.749 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 1.828301e-03 | 2.738 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.864102e-03 | 2.730 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 1.864102e-03 | 2.730 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 1.952238e-03 | 2.709 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 1.853375e-03 | 2.732 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.911577e-03 | 2.719 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.864102e-03 | 2.730 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 1.805895e-03 | 2.743 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.985387e-03 | 2.702 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 2.005103e-03 | 2.698 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 2.017892e-03 | 2.695 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 2.354181e-03 | 2.628 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 2.354181e-03 | 2.628 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 2.354622e-03 | 2.628 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 2.354622e-03 | 2.628 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 2.292733e-03 | 2.640 | 1 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 2.312977e-03 | 2.636 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.237843e-03 | 2.650 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 2.350883e-03 | 2.629 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.237816e-03 | 2.650 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 2.167377e-03 | 2.664 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 2.254252e-03 | 2.647 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 2.518952e-03 | 2.599 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 2.518952e-03 | 2.599 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 2.518952e-03 | 2.599 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 2.667830e-03 | 2.574 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 2.681644e-03 | 2.572 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.894771e-03 | 2.538 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 3.002638e-03 | 2.522 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 3.082997e-03 | 2.511 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 3.121451e-03 | 2.506 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.327817e-03 | 2.478 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 3.422205e-03 | 2.466 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 3.522256e-03 | 2.453 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 3.576614e-03 | 2.447 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 4.074142e-03 | 2.390 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 3.764092e-03 | 2.424 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 4.159710e-03 | 2.381 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 4.159710e-03 | 2.381 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 4.313729e-03 | 2.365 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 4.313729e-03 | 2.365 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 4.559907e-03 | 2.341 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 4.580786e-03 | 2.339 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 4.661883e-03 | 2.331 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 4.661883e-03 | 2.331 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 4.736424e-03 | 2.325 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 4.736424e-03 | 2.325 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 4.767641e-03 | 2.322 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 4.837561e-03 | 2.315 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 5.315430e-03 | 2.274 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 5.228238e-03 | 2.282 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 5.228238e-03 | 2.282 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 5.505853e-03 | 2.259 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 5.509516e-03 | 2.259 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 5.618556e-03 | 2.250 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 5.436024e-03 | 2.265 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 5.863665e-03 | 2.232 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 5.981737e-03 | 2.223 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 6.123784e-03 | 2.213 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 6.123784e-03 | 2.213 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 6.204126e-03 | 2.207 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 6.204126e-03 | 2.207 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 6.416447e-03 | 2.193 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 6.466573e-03 | 2.189 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 6.586510e-03 | 2.181 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 6.673915e-03 | 2.176 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 6.775819e-03 | 2.169 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 6.787890e-03 | 2.168 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 7.968714e-03 | 2.099 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 7.968714e-03 | 2.099 | 0 | 0 |
| Protein folding | R-HSA-391251 | 7.110011e-03 | 2.148 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 7.401169e-03 | 2.131 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 7.968714e-03 | 2.099 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 8.236450e-03 | 2.084 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 8.285192e-03 | 2.082 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 8.637406e-03 | 2.064 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 8.651854e-03 | 2.063 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 8.722338e-03 | 2.059 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 8.722338e-03 | 2.059 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.768595e-03 | 2.057 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 8.901934e-03 | 2.051 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 9.327321e-03 | 2.030 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 9.430994e-03 | 2.025 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 9.592042e-03 | 2.018 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 9.592042e-03 | 2.018 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 9.802793e-03 | 2.009 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 9.817286e-03 | 2.008 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 1.110930e-02 | 1.954 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 1.110930e-02 | 1.954 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 9.845246e-03 | 2.007 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 9.845246e-03 | 2.007 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 1.052680e-02 | 1.978 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.000281e-02 | 2.000 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.038869e-02 | 1.983 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 1.022394e-02 | 1.990 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.124327e-02 | 1.949 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.124327e-02 | 1.949 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.122068e-02 | 1.950 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 9.993310e-03 | 2.000 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 1.144455e-02 | 1.941 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.146173e-02 | 1.941 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 1.174315e-02 | 1.930 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.177154e-02 | 1.929 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 1.186950e-02 | 1.926 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.213312e-02 | 1.916 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.223225e-02 | 1.912 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 1.223225e-02 | 1.912 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.226039e-02 | 1.911 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 1.228699e-02 | 1.911 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 1.285045e-02 | 1.891 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 1.285045e-02 | 1.891 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 1.285045e-02 | 1.891 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.317833e-02 | 1.880 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.442184e-02 | 1.841 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.461425e-02 | 1.835 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.488222e-02 | 1.827 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 1.488222e-02 | 1.827 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.529038e-02 | 1.816 | 1 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 1.548004e-02 | 1.810 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 1.841727e-02 | 1.735 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.649848e-02 | 1.783 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.649848e-02 | 1.783 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.775936e-02 | 1.751 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.778131e-02 | 1.750 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.658386e-02 | 1.780 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 1.615420e-02 | 1.792 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.597275e-02 | 1.797 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 1.844838e-02 | 1.734 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.892668e-02 | 1.723 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.992844e-02 | 1.701 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.992844e-02 | 1.701 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.992844e-02 | 1.701 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.992844e-02 | 1.701 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 2.018889e-02 | 1.695 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 2.018889e-02 | 1.695 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 2.018889e-02 | 1.695 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 2.018889e-02 | 1.695 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 2.018889e-02 | 1.695 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.018889e-02 | 1.695 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 2.027373e-02 | 1.693 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 2.027373e-02 | 1.693 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 2.027373e-02 | 1.693 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.128426e-02 | 1.672 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.137668e-02 | 1.670 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.137668e-02 | 1.670 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 2.144096e-02 | 1.669 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 2.200549e-02 | 1.657 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 2.251033e-02 | 1.648 | 1 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 2.296728e-02 | 1.639 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 2.310005e-02 | 1.636 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 2.813467e-02 | 1.551 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 2.463507e-02 | 1.608 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.550179e-02 | 1.593 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.550179e-02 | 1.593 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 2.568225e-02 | 1.590 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 2.666571e-02 | 1.574 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.498249e-02 | 1.602 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.569660e-02 | 1.590 | 0 | 0 |
| S Phase | R-HSA-69242 | 2.397288e-02 | 1.620 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 2.813467e-02 | 1.551 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 2.793709e-02 | 1.554 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 2.813467e-02 | 1.551 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 2.579582e-02 | 1.588 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 2.579582e-02 | 1.588 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 2.513404e-02 | 1.600 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 2.801000e-02 | 1.553 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 2.801000e-02 | 1.553 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 2.498249e-02 | 1.602 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 2.815078e-02 | 1.551 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.822804e-02 | 1.549 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 2.822804e-02 | 1.549 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.825487e-02 | 1.549 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.954809e-02 | 1.529 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 2.962411e-02 | 1.528 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 2.962411e-02 | 1.528 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 3.014109e-02 | 1.521 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 3.016838e-02 | 1.520 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 3.016838e-02 | 1.520 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 3.068974e-02 | 1.513 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 3.215050e-02 | 1.493 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 3.215050e-02 | 1.493 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 3.215050e-02 | 1.493 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 3.215050e-02 | 1.493 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.325881e-02 | 1.478 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 3.328888e-02 | 1.478 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 3.328888e-02 | 1.478 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 3.328888e-02 | 1.478 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 3.328888e-02 | 1.478 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 3.328888e-02 | 1.478 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 3.328888e-02 | 1.478 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 3.328888e-02 | 1.478 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 3.365825e-02 | 1.473 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 3.406727e-02 | 1.468 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 3.419397e-02 | 1.466 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 3.432837e-02 | 1.464 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 3.498508e-02 | 1.456 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.512860e-02 | 1.454 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 3.527895e-02 | 1.452 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 3.527895e-02 | 1.452 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 3.527895e-02 | 1.452 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 3.540773e-02 | 1.451 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 3.607675e-02 | 1.443 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 4.532850e-02 | 1.344 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 4.122988e-02 | 1.385 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 4.124826e-02 | 1.385 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 4.771508e-02 | 1.321 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 4.035218e-02 | 1.394 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 4.035218e-02 | 1.394 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.912883e-02 | 1.408 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 4.807607e-02 | 1.318 | 1 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 4.807607e-02 | 1.318 | 1 | 1 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 4.807607e-02 | 1.318 | 1 | 1 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 4.807607e-02 | 1.318 | 1 | 1 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 4.452839e-02 | 1.351 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 4.001188e-02 | 1.398 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 3.912883e-02 | 1.408 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 4.307013e-02 | 1.366 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 4.088394e-02 | 1.388 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 3.912883e-02 | 1.408 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 3.960592e-02 | 1.402 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.941409e-02 | 1.404 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 4.124826e-02 | 1.385 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 3.941409e-02 | 1.404 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 4.368660e-02 | 1.360 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 4.122988e-02 | 1.385 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 4.454305e-02 | 1.351 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 4.753598e-02 | 1.323 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 4.438613e-02 | 1.353 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 4.807607e-02 | 1.318 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 4.454305e-02 | 1.351 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 4.122988e-02 | 1.385 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 4.736739e-02 | 1.325 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 4.330155e-02 | 1.363 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 4.810722e-02 | 1.318 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 4.810722e-02 | 1.318 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 4.822166e-02 | 1.317 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 4.871706e-02 | 1.312 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 4.871706e-02 | 1.312 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 4.871706e-02 | 1.312 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 4.871706e-02 | 1.312 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 4.877800e-02 | 1.312 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 4.899446e-02 | 1.310 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 4.983339e-02 | 1.302 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 5.001614e-02 | 1.301 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 5.036499e-02 | 1.298 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 5.036499e-02 | 1.298 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 5.045426e-02 | 1.297 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.045426e-02 | 1.297 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 5.358799e-02 | 1.271 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 5.365260e-02 | 1.270 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 5.482962e-02 | 1.261 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 5.482962e-02 | 1.261 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 5.482962e-02 | 1.261 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 5.483078e-02 | 1.261 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 5.483078e-02 | 1.261 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.483078e-02 | 1.261 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 5.483078e-02 | 1.261 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 5.483078e-02 | 1.261 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 5.554780e-02 | 1.255 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 5.554780e-02 | 1.255 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 5.554780e-02 | 1.255 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 5.554780e-02 | 1.255 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 5.593135e-02 | 1.252 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 5.593135e-02 | 1.252 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 5.687792e-02 | 1.245 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 5.768685e-02 | 1.239 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 6.027095e-02 | 1.220 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 6.194900e-02 | 1.208 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 6.251835e-02 | 1.204 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 6.452185e-02 | 1.190 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 6.516140e-02 | 1.186 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 6.676113e-02 | 1.175 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 6.721438e-02 | 1.173 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 6.721438e-02 | 1.173 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 6.721438e-02 | 1.173 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 6.745079e-02 | 1.171 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 6.834980e-02 | 1.165 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 6.834980e-02 | 1.165 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 6.834980e-02 | 1.165 | 0 | 0 |
| Transport of glycerol from adipocytes to the liver by Aquaporins | R-HSA-432030 | 6.834980e-02 | 1.165 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 6.834980e-02 | 1.165 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 6.946538e-02 | 1.158 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 7.106741e-02 | 1.148 | 1 | 1 |
| Mitophagy | R-HSA-5205647 | 7.106741e-02 | 1.148 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 7.131251e-02 | 1.147 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 7.308717e-02 | 1.136 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 7.308717e-02 | 1.136 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 7.308717e-02 | 1.136 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 7.308717e-02 | 1.136 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 7.308717e-02 | 1.136 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 7.308717e-02 | 1.136 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 7.455314e-02 | 1.128 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 7.570703e-02 | 1.121 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 7.871450e-02 | 1.104 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 7.871450e-02 | 1.104 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 7.871450e-02 | 1.104 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 8.125412e-02 | 1.090 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 8.014887e-02 | 1.096 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 8.014887e-02 | 1.096 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 9.303377e-02 | 1.031 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 9.303377e-02 | 1.031 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 1.014339e-01 | 0.994 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 7.934196e-02 | 1.100 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 7.934196e-02 | 1.100 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 9.405500e-02 | 1.027 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 9.925627e-02 | 1.003 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.008346e-01 | 0.996 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 8.198569e-02 | 1.086 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 8.198569e-02 | 1.086 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 7.647249e-02 | 1.116 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.977463e-02 | 1.098 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 8.910843e-02 | 1.050 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 7.868685e-02 | 1.104 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 9.004921e-02 | 1.046 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 9.374340e-02 | 1.028 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 7.977463e-02 | 1.098 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 8.457410e-02 | 1.073 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 8.095380e-02 | 1.092 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.561711e-02 | 1.019 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 7.871450e-02 | 1.104 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 9.308814e-02 | 1.031 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 8.285974e-02 | 1.082 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 9.046428e-02 | 1.044 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 8.254612e-02 | 1.083 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 9.374775e-02 | 1.028 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 9.438026e-02 | 1.025 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 7.613142e-02 | 1.118 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 7.636105e-02 | 1.117 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 9.349551e-02 | 1.029 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 9.308814e-02 | 1.031 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.014072e-01 | 0.994 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 7.868685e-02 | 1.104 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.013515e-01 | 0.994 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 8.840155e-02 | 1.054 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 7.977463e-02 | 1.098 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 7.769989e-02 | 1.110 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 7.723131e-02 | 1.112 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 1.019104e-01 | 0.992 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 1.025796e-01 | 0.989 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 1.063159e-01 | 0.973 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.063159e-01 | 0.973 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.063159e-01 | 0.973 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.067324e-01 | 0.972 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 1.067324e-01 | 0.972 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.067324e-01 | 0.972 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 1.070025e-01 | 0.971 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.084543e-01 | 0.965 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.106637e-01 | 0.956 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.108436e-01 | 0.955 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 1.110140e-01 | 0.955 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 1.110140e-01 | 0.955 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 1.110140e-01 | 0.955 | 0 | 0 |
| Signaling by RAS GAP mutants | R-HSA-9753510 | 1.110140e-01 | 0.955 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 1.116417e-01 | 0.952 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 1.119754e-01 | 0.951 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 1.119754e-01 | 0.951 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 1.119754e-01 | 0.951 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.153834e-01 | 0.938 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 1.153834e-01 | 0.938 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 1.153834e-01 | 0.938 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.153834e-01 | 0.938 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.154502e-01 | 0.938 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 1.169614e-01 | 0.932 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 1.176651e-01 | 0.929 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.179749e-01 | 0.928 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 1.186855e-01 | 0.926 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 1.192078e-01 | 0.924 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 1.194979e-01 | 0.923 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 1.199968e-01 | 0.921 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 1.199968e-01 | 0.921 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.201169e-01 | 0.920 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.236801e-01 | 0.908 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 1.260302e-01 | 0.900 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.285397e-01 | 0.891 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 1.285397e-01 | 0.891 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 1.286204e-01 | 0.891 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 1.289787e-01 | 0.889 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.292976e-01 | 0.888 | 0 | 0 |
| Drug resistance of PDGFR mutants | R-HSA-9674415 | 1.320794e-01 | 0.879 | 0 | 0 |
| PDGFR mutants bind TKIs | R-HSA-9674428 | 1.320794e-01 | 0.879 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.320794e-01 | 0.879 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.320794e-01 | 0.879 | 0 | 0 |
| Regorafenib-resistant PDGFR mutants | R-HSA-9674403 | 1.320794e-01 | 0.879 | 0 | 0 |
| Sunitinib-resistant PDGFR mutants | R-HSA-9674401 | 1.320794e-01 | 0.879 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.320794e-01 | 0.879 | 0 | 0 |
| Imatinib-resistant PDGFR mutants | R-HSA-9674396 | 1.320794e-01 | 0.879 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.320794e-01 | 0.879 | 0 | 0 |
| Sorafenib-resistant PDGFR mutants | R-HSA-9674404 | 1.320794e-01 | 0.879 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.467204e-01 | 0.608 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 2.467204e-01 | 0.608 | 0 | 0 |
| Impaired BRCA2 translocation to the nucleus | R-HSA-9709275 | 2.467204e-01 | 0.608 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.467204e-01 | 0.608 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.467204e-01 | 0.608 | 0 | 0 |
| Impaired BRCA2 binding to SEM1 (DSS1) | R-HSA-9763198 | 2.467204e-01 | 0.608 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 2.467204e-01 | 0.608 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.467204e-01 | 0.608 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 2.467204e-01 | 0.608 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of other transcription factors | R-HSA-8866906 | 1.586631e-01 | 0.800 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.586631e-01 | 0.800 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 1.586631e-01 | 0.800 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 1.586631e-01 | 0.800 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 1.586631e-01 | 0.800 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 1.586631e-01 | 0.800 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 1.370907e-01 | 0.863 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 2.092372e-01 | 0.679 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 2.092372e-01 | 0.679 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 2.092372e-01 | 0.679 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 2.092372e-01 | 0.679 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 2.092372e-01 | 0.679 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 2.092372e-01 | 0.679 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 2.092372e-01 | 0.679 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 2.092372e-01 | 0.679 | 0 | 0 |
| Nef mediated downregulation of CD28 cell surface expression | R-HSA-164939 | 3.462246e-01 | 0.461 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 3.462246e-01 | 0.461 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5619081 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI) | R-HSA-5619099 | 3.462246e-01 | 0.461 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 3.462246e-01 | 0.461 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5660724 | 3.462246e-01 | 0.461 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 3.462246e-01 | 0.461 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 3.462246e-01 | 0.461 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 1.704611e-01 | 0.768 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 1.704611e-01 | 0.768 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.704611e-01 | 0.768 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 1.704611e-01 | 0.768 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 1.704611e-01 | 0.768 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 1.397624e-01 | 0.855 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.611335e-01 | 0.583 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.611335e-01 | 0.583 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 2.611335e-01 | 0.583 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 2.611335e-01 | 0.583 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 2.611335e-01 | 0.583 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 2.058483e-01 | 0.686 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 2.058483e-01 | 0.686 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 1.659836e-01 | 0.780 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 1.659836e-01 | 0.780 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 1.659836e-01 | 0.780 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.659836e-01 | 0.780 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.659836e-01 | 0.780 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 1.356948e-01 | 0.867 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.573868e-01 | 0.803 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 1.573868e-01 | 0.803 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.937859e-01 | 0.713 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.937859e-01 | 0.713 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.937859e-01 | 0.713 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.937859e-01 | 0.713 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.937859e-01 | 0.713 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.937859e-01 | 0.713 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 2.426964e-01 | 0.615 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 3.131209e-01 | 0.504 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 3.131209e-01 | 0.504 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 3.131209e-01 | 0.504 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 3.131209e-01 | 0.504 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 3.131209e-01 | 0.504 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 3.131209e-01 | 0.504 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 3.131209e-01 | 0.504 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.477359e-01 | 0.831 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 1.803860e-01 | 0.744 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.803860e-01 | 0.744 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 2.228980e-01 | 0.652 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 2.228980e-01 | 0.652 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 2.228980e-01 | 0.652 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.228980e-01 | 0.652 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 2.228980e-01 | 0.652 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 1.380662e-01 | 0.860 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 2.804872e-01 | 0.552 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 2.804872e-01 | 0.552 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 2.804872e-01 | 0.552 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 2.804872e-01 | 0.552 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 2.045399e-01 | 0.689 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 2.045399e-01 | 0.689 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 2.045399e-01 | 0.689 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 1.550727e-01 | 0.809 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 1.437293e-01 | 0.842 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 1.879397e-01 | 0.726 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 2.530468e-01 | 0.597 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 2.530468e-01 | 0.597 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 2.530468e-01 | 0.597 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 3.642705e-01 | 0.439 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 3.642705e-01 | 0.439 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 3.642705e-01 | 0.439 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 3.642705e-01 | 0.439 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 3.642705e-01 | 0.439 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 3.642705e-01 | 0.439 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 1.332834e-01 | 0.875 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 1.332834e-01 | 0.875 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.729881e-01 | 0.762 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.296876e-01 | 0.639 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 2.296876e-01 | 0.639 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 2.296876e-01 | 0.639 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 2.094727e-01 | 0.679 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 3.187497e-01 | 0.497 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 3.187497e-01 | 0.497 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 3.187497e-01 | 0.497 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 3.187497e-01 | 0.497 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 3.187497e-01 | 0.497 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 3.187497e-01 | 0.497 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 3.187497e-01 | 0.497 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 1.917471e-01 | 0.717 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 2.839641e-01 | 0.547 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 2.839641e-01 | 0.547 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.839641e-01 | 0.547 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.839641e-01 | 0.547 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 2.839641e-01 | 0.547 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.839641e-01 | 0.547 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 1.620260e-01 | 0.790 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.556635e-01 | 0.592 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 2.556635e-01 | 0.592 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 2.556635e-01 | 0.592 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 2.318188e-01 | 0.635 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 2.318188e-01 | 0.635 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 2.318188e-01 | 0.635 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 2.112779e-01 | 0.675 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 2.112779e-01 | 0.675 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 2.112779e-01 | 0.675 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 2.112779e-01 | 0.675 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 2.112779e-01 | 0.675 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 1.776612e-01 | 0.750 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 1.776612e-01 | 0.750 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 2.315037e-01 | 0.635 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 2.548662e-01 | 0.594 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 2.548662e-01 | 0.594 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 2.823011e-01 | 0.549 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 2.823011e-01 | 0.549 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 2.823011e-01 | 0.549 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 2.823011e-01 | 0.549 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 3.153923e-01 | 0.501 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 3.153923e-01 | 0.501 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 3.153923e-01 | 0.501 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 3.570655e-01 | 0.447 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.506300e-01 | 0.822 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 2.297908e-01 | 0.639 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 2.523438e-01 | 0.598 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 3.094352e-01 | 0.509 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 3.094352e-01 | 0.509 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 2.272381e-01 | 0.644 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.470881e-01 | 0.460 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 3.470881e-01 | 0.460 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.057535e-01 | 0.687 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 2.737145e-01 | 0.563 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 1.344029e-01 | 0.872 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 3.950700e-01 | 0.403 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 3.950700e-01 | 0.403 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 3.950700e-01 | 0.403 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 3.950700e-01 | 0.403 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 3.950700e-01 | 0.403 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 3.950700e-01 | 0.403 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 3.950700e-01 | 0.403 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 3.950700e-01 | 0.403 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 2.406388e-01 | 0.619 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 3.369054e-01 | 0.472 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 3.369054e-01 | 0.472 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 2.630252e-01 | 0.580 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 2.630252e-01 | 0.580 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 2.630252e-01 | 0.580 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.613902e-01 | 0.792 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 2.317432e-01 | 0.635 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 3.270694e-01 | 0.485 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 3.270694e-01 | 0.485 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 1.709926e-01 | 0.767 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 2.059440e-01 | 0.686 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.808877e-01 | 0.743 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.713713e-01 | 0.766 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.713713e-01 | 0.766 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 2.682645e-01 | 0.571 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 3.004046e-01 | 0.522 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 2.639473e-01 | 0.578 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 3.016005e-01 | 0.521 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 2.004520e-01 | 0.698 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 2.004520e-01 | 0.698 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 2.004520e-01 | 0.698 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 3.627983e-01 | 0.440 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 3.389490e-01 | 0.470 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.008967e-01 | 0.522 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 2.514603e-01 | 0.600 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 3.359333e-01 | 0.474 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 3.585228e-01 | 0.445 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 3.652762e-01 | 0.437 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 3.652762e-01 | 0.437 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 3.542678e-01 | 0.451 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 3.146334e-01 | 0.502 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 2.449066e-01 | 0.611 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 3.017237e-01 | 0.520 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 2.842732e-01 | 0.546 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.021725e-01 | 0.694 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 1.846478e-01 | 0.734 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 3.177069e-01 | 0.498 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 2.523438e-01 | 0.598 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 3.320858e-01 | 0.479 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 3.320858e-01 | 0.479 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 2.518531e-01 | 0.599 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 1.906073e-01 | 0.720 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 1.620260e-01 | 0.790 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 3.766220e-01 | 0.424 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 3.570655e-01 | 0.447 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 1.673271e-01 | 0.776 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 3.533785e-01 | 0.452 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 3.153923e-01 | 0.501 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 3.153923e-01 | 0.501 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 2.272381e-01 | 0.644 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 2.297908e-01 | 0.639 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 3.950700e-01 | 0.403 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 3.922458e-01 | 0.406 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 1.760455e-01 | 0.754 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.177069e-01 | 0.498 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 1.803860e-01 | 0.744 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 2.530468e-01 | 0.597 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 1.473025e-01 | 0.832 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.449066e-01 | 0.611 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 3.316600e-01 | 0.479 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 2.134832e-01 | 0.671 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 1.917471e-01 | 0.717 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.933112e-01 | 0.714 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.393875e-01 | 0.856 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 3.517776e-01 | 0.454 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 3.924644e-01 | 0.406 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 2.815423e-01 | 0.550 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 2.296876e-01 | 0.639 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 2.924037e-01 | 0.534 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 2.924037e-01 | 0.534 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 3.075098e-01 | 0.512 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 2.649795e-01 | 0.577 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 3.131209e-01 | 0.504 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.804872e-01 | 0.552 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 2.094727e-01 | 0.679 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 2.094727e-01 | 0.679 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 1.934489e-01 | 0.713 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 2.272381e-01 | 0.644 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.541351e-01 | 0.812 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 3.503361e-01 | 0.456 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 3.533785e-01 | 0.452 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.676994e-01 | 0.435 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 2.705890e-01 | 0.568 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 3.026063e-01 | 0.519 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 1.910680e-01 | 0.719 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 2.699407e-01 | 0.569 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.933112e-01 | 0.714 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.774206e-01 | 0.751 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 3.389490e-01 | 0.470 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 3.258414e-01 | 0.487 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 2.092372e-01 | 0.679 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 2.611335e-01 | 0.583 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 2.058483e-01 | 0.686 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 3.642705e-01 | 0.439 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 3.642705e-01 | 0.439 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 2.296876e-01 | 0.639 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.094727e-01 | 0.679 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 3.094352e-01 | 0.509 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 2.207745e-01 | 0.656 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 1.489353e-01 | 0.827 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.413165e-01 | 0.850 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 3.482012e-01 | 0.458 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.479398e-01 | 0.458 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 1.729881e-01 | 0.762 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.823011e-01 | 0.549 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 3.194054e-01 | 0.496 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.369332e-01 | 0.863 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 3.590282e-01 | 0.445 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 3.561943e-01 | 0.448 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 1.659836e-01 | 0.780 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 3.950700e-01 | 0.403 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 3.950700e-01 | 0.403 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 3.766220e-01 | 0.424 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 3.705675e-01 | 0.431 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 3.413625e-01 | 0.467 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 3.153923e-01 | 0.501 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 2.580272e-01 | 0.588 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 2.489251e-01 | 0.604 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.823011e-01 | 0.549 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 2.847891e-01 | 0.545 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 1.424226e-01 | 0.846 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 2.955308e-01 | 0.529 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 2.045399e-01 | 0.689 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 1.620260e-01 | 0.790 | 0 | 0 |
| Activation and oligomerization of BAK protein | R-HSA-111452 | 2.467204e-01 | 0.608 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 1.586631e-01 | 0.800 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 2.611335e-01 | 0.583 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 2.426964e-01 | 0.615 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 3.131209e-01 | 0.504 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 2.045399e-01 | 0.689 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 2.737145e-01 | 0.563 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 3.788258e-01 | 0.422 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 2.499326e-01 | 0.602 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 3.389490e-01 | 0.470 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 3.709586e-01 | 0.431 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 3.709586e-01 | 0.431 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 3.709586e-01 | 0.431 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 3.709586e-01 | 0.431 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.926900e-01 | 0.406 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 2.057535e-01 | 0.687 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 2.613526e-01 | 0.583 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.657921e-01 | 0.575 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 3.144271e-01 | 0.502 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 3.470881e-01 | 0.460 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 3.187497e-01 | 0.497 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 3.855477e-01 | 0.414 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 2.613526e-01 | 0.583 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 2.228980e-01 | 0.652 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 1.508575e-01 | 0.821 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 3.095085e-01 | 0.509 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 2.850435e-01 | 0.545 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 2.949019e-01 | 0.530 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 2.949019e-01 | 0.530 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 3.780122e-01 | 0.422 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 3.780122e-01 | 0.422 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 2.449066e-01 | 0.611 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 1.370907e-01 | 0.863 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 3.131209e-01 | 0.504 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 3.131209e-01 | 0.504 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 3.153923e-01 | 0.501 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 1.368293e-01 | 0.864 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 3.294714e-01 | 0.482 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 2.518531e-01 | 0.599 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 1.870797e-01 | 0.728 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 1.933112e-01 | 0.714 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 2.112779e-01 | 0.675 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 2.775274e-01 | 0.557 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 2.611335e-01 | 0.583 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.737025e-01 | 0.760 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 1.620260e-01 | 0.790 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 1.933112e-01 | 0.714 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 2.004974e-01 | 0.698 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 3.730033e-01 | 0.428 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 2.469811e-01 | 0.607 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 3.106167e-01 | 0.508 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 3.163952e-01 | 0.500 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 3.016005e-01 | 0.521 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 2.449066e-01 | 0.611 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.445248e-01 | 0.463 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.681651e-01 | 0.774 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 3.768962e-01 | 0.424 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 1.772761e-01 | 0.751 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.594341e-01 | 0.797 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 3.320858e-01 | 0.479 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 2.190642e-01 | 0.659 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 2.467204e-01 | 0.608 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 2.467204e-01 | 0.608 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 1.586631e-01 | 0.800 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 2.092372e-01 | 0.679 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.462246e-01 | 0.461 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.462246e-01 | 0.461 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 2.611335e-01 | 0.583 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 2.611335e-01 | 0.583 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 2.426964e-01 | 0.615 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 2.426964e-01 | 0.615 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.804872e-01 | 0.552 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 2.804872e-01 | 0.552 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.729881e-01 | 0.762 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 3.570655e-01 | 0.447 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 3.570655e-01 | 0.447 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 3.740002e-01 | 0.427 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 1.955639e-01 | 0.709 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.937599e-01 | 0.713 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 3.300898e-01 | 0.481 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 2.578954e-01 | 0.589 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.531311e-01 | 0.815 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.531311e-01 | 0.815 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 2.122492e-01 | 0.673 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 2.272571e-01 | 0.643 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 2.059440e-01 | 0.686 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 2.122492e-01 | 0.673 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 2.122492e-01 | 0.673 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 3.187497e-01 | 0.497 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 3.186612e-01 | 0.497 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.705890e-01 | 0.568 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 3.652762e-01 | 0.437 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 3.709586e-01 | 0.431 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 2.426964e-01 | 0.615 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 2.296876e-01 | 0.639 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.187497e-01 | 0.497 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 2.556635e-01 | 0.592 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 3.470881e-01 | 0.460 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.884703e-01 | 0.540 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 3.574991e-01 | 0.447 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 2.556635e-01 | 0.592 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 3.947999e-01 | 0.404 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 1.659836e-01 | 0.780 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 2.576080e-01 | 0.589 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 2.927596e-01 | 0.533 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 2.782307e-01 | 0.556 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 2.530468e-01 | 0.597 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 3.389490e-01 | 0.470 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.400785e-01 | 0.854 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 1.505214e-01 | 0.822 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 2.100696e-01 | 0.678 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.788258e-01 | 0.422 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 3.645576e-01 | 0.438 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 1.673271e-01 | 0.776 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 2.847891e-01 | 0.545 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 1.586631e-01 | 0.800 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 1.370907e-01 | 0.863 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.426964e-01 | 0.615 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 2.804872e-01 | 0.552 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 2.583404e-01 | 0.588 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 1.620260e-01 | 0.790 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 2.112779e-01 | 0.675 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 2.641377e-01 | 0.578 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 2.523438e-01 | 0.598 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 3.369054e-01 | 0.472 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 2.556635e-01 | 0.592 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 3.277259e-01 | 0.484 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 2.809127e-01 | 0.551 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 1.586631e-01 | 0.800 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 2.611335e-01 | 0.583 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 3.131209e-01 | 0.504 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.879397e-01 | 0.726 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 3.470881e-01 | 0.460 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 2.398668e-01 | 0.620 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 3.088272e-01 | 0.510 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 3.720275e-01 | 0.429 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 3.961946e-01 | 0.402 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 3.980058e-01 | 0.400 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.014985e-01 | 0.396 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 4.014985e-01 | 0.396 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 4.040566e-01 | 0.394 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 4.063719e-01 | 0.391 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 4.083263e-01 | 0.389 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 4.083263e-01 | 0.389 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 4.101827e-01 | 0.387 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 4.103995e-01 | 0.387 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 4.103995e-01 | 0.387 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 4.103995e-01 | 0.387 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 4.136006e-01 | 0.383 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 4.138967e-01 | 0.383 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 4.138967e-01 | 0.383 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 4.138967e-01 | 0.383 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 4.138967e-01 | 0.383 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 4.138967e-01 | 0.383 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 4.138967e-01 | 0.383 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 4.138967e-01 | 0.383 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 4.138967e-01 | 0.383 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 4.138967e-01 | 0.383 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 4.138967e-01 | 0.383 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 4.138967e-01 | 0.383 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 4.138967e-01 | 0.383 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 4.178110e-01 | 0.379 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 4.198334e-01 | 0.377 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 4.198334e-01 | 0.377 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 4.198334e-01 | 0.377 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 4.212566e-01 | 0.375 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 4.212566e-01 | 0.375 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 4.231658e-01 | 0.373 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 4.234728e-01 | 0.373 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 4.241311e-01 | 0.372 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 4.265665e-01 | 0.370 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 4.265665e-01 | 0.370 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 4.310584e-01 | 0.365 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 4.324520e-01 | 0.364 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 4.324520e-01 | 0.364 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.324520e-01 | 0.364 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 4.324520e-01 | 0.364 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 4.325899e-01 | 0.364 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 4.325899e-01 | 0.364 | 0 | 0 |
| Interaction between PHLDA1 and AURKA | R-HSA-8854521 | 4.325899e-01 | 0.364 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 4.325899e-01 | 0.364 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 4.325899e-01 | 0.364 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 4.325899e-01 | 0.364 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 4.325899e-01 | 0.364 | 0 | 0 |
| Glycogen storage disease type II (GAA) | R-HSA-5357609 | 4.325899e-01 | 0.364 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 4.325899e-01 | 0.364 | 0 | 0 |
| Defective SLC12A1 causes Bartter syndrome 1 (BS1) | R-HSA-5619104 | 4.325899e-01 | 0.364 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 4.325899e-01 | 0.364 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 4.346864e-01 | 0.362 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 4.382282e-01 | 0.358 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 4.410181e-01 | 0.356 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 4.416239e-01 | 0.355 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 4.416239e-01 | 0.355 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 4.416239e-01 | 0.355 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 4.416239e-01 | 0.355 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 4.416239e-01 | 0.355 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 4.448904e-01 | 0.352 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 4.460785e-01 | 0.351 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 4.471947e-01 | 0.350 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 4.471947e-01 | 0.350 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 4.500891e-01 | 0.347 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 4.536719e-01 | 0.343 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 4.536719e-01 | 0.343 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 4.557147e-01 | 0.341 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 4.557147e-01 | 0.341 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 4.615098e-01 | 0.336 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 4.615098e-01 | 0.336 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 4.615098e-01 | 0.336 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 4.615098e-01 | 0.336 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 4.615098e-01 | 0.336 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 4.615098e-01 | 0.336 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 4.615098e-01 | 0.336 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 4.615098e-01 | 0.336 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 4.615098e-01 | 0.336 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 4.621373e-01 | 0.335 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 4.625361e-01 | 0.335 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 4.628706e-01 | 0.335 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 4.628706e-01 | 0.335 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 4.631510e-01 | 0.334 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 4.631510e-01 | 0.334 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 4.689518e-01 | 0.329 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 4.689518e-01 | 0.329 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 4.689518e-01 | 0.329 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 4.689518e-01 | 0.329 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 4.723352e-01 | 0.326 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.723352e-01 | 0.326 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 4.723352e-01 | 0.326 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 4.723352e-01 | 0.326 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 4.723352e-01 | 0.326 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 4.742145e-01 | 0.324 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 4.742145e-01 | 0.324 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 4.742145e-01 | 0.324 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 4.753631e-01 | 0.323 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 4.753631e-01 | 0.323 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 4.760994e-01 | 0.322 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 4.765053e-01 | 0.322 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.768906e-01 | 0.322 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 4.772329e-01 | 0.321 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 4.903883e-01 | 0.309 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 4.954738e-01 | 0.305 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 4.963195e-01 | 0.304 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 4.972469e-01 | 0.303 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 4.972469e-01 | 0.303 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 4.972469e-01 | 0.303 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 4.972469e-01 | 0.303 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 4.982776e-01 | 0.303 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 4.982776e-01 | 0.303 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 4.982776e-01 | 0.303 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 4.994429e-01 | 0.302 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 4.994429e-01 | 0.302 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 4.994429e-01 | 0.302 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 5.023908e-01 | 0.299 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 5.023908e-01 | 0.299 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 5.023908e-01 | 0.299 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 5.023908e-01 | 0.299 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 5.023908e-01 | 0.299 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 5.043573e-01 | 0.297 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 5.043573e-01 | 0.297 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 5.043573e-01 | 0.297 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 5.043573e-01 | 0.297 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 5.048450e-01 | 0.297 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 5.067757e-01 | 0.295 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 5.067757e-01 | 0.295 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 5.067757e-01 | 0.295 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 5.067757e-01 | 0.295 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 5.067757e-01 | 0.295 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 5.067757e-01 | 0.295 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 5.067757e-01 | 0.295 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 5.067757e-01 | 0.295 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 5.067757e-01 | 0.295 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 5.067757e-01 | 0.295 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 5.067757e-01 | 0.295 | 0 | 0 |
| Activated NTRK3 signals through PLCG1 | R-HSA-9034793 | 5.075504e-01 | 0.295 | 0 | 0 |
| PLC-gamma1 signalling | R-HSA-167021 | 5.075504e-01 | 0.295 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 5.075504e-01 | 0.295 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 5.075504e-01 | 0.295 | 0 | 0 |
| Adrenaline signalling through Alpha-2 adrenergic receptor | R-HSA-392023 | 5.075504e-01 | 0.295 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 5.075504e-01 | 0.295 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 5.075504e-01 | 0.295 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 5.075504e-01 | 0.295 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 5.075504e-01 | 0.295 | 0 | 0 |
| Activation of BMF and translocation to mitochondria | R-HSA-139910 | 5.075504e-01 | 0.295 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 5.075504e-01 | 0.295 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 5.075504e-01 | 0.295 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 5.075504e-01 | 0.295 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 5.214759e-01 | 0.283 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 5.231260e-01 | 0.281 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 5.231260e-01 | 0.281 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 5.231260e-01 | 0.281 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 5.231260e-01 | 0.281 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 5.268284e-01 | 0.278 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 5.268284e-01 | 0.278 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 5.270352e-01 | 0.278 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 5.316690e-01 | 0.274 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 5.316690e-01 | 0.274 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 5.317120e-01 | 0.274 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 5.317120e-01 | 0.274 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 5.324360e-01 | 0.274 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 5.345317e-01 | 0.272 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 5.370514e-01 | 0.270 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 5.385005e-01 | 0.269 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 5.385005e-01 | 0.269 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 5.385005e-01 | 0.269 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 5.385005e-01 | 0.269 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 5.385005e-01 | 0.269 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 5.385005e-01 | 0.269 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 5.416587e-01 | 0.266 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 5.416587e-01 | 0.266 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 5.420994e-01 | 0.266 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 5.440590e-01 | 0.264 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 5.456223e-01 | 0.263 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 5.462204e-01 | 0.263 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 5.494837e-01 | 0.260 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 5.494837e-01 | 0.260 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 5.494837e-01 | 0.260 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 5.494837e-01 | 0.260 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 5.494837e-01 | 0.260 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 5.494837e-01 | 0.260 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 5.494837e-01 | 0.260 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 5.502055e-01 | 0.259 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 5.522504e-01 | 0.258 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 5.575951e-01 | 0.254 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 5.600678e-01 | 0.252 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 5.600678e-01 | 0.252 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 5.600678e-01 | 0.252 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 5.600678e-01 | 0.252 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 5.608794e-01 | 0.251 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 5.650081e-01 | 0.248 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 5.690510e-01 | 0.245 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 5.690510e-01 | 0.245 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 5.712532e-01 | 0.243 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 5.712532e-01 | 0.243 | 0 | 0 |
| Activated NTRK2 signals through PLCG1 | R-HSA-9026527 | 5.726116e-01 | 0.242 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 5.726116e-01 | 0.242 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 5.726116e-01 | 0.242 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 5.726116e-01 | 0.242 | 0 | 0 |
| Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate | R-HSA-2978092 | 5.726116e-01 | 0.242 | 0 | 0 |
| Vasopressin-like receptors | R-HSA-388479 | 5.726116e-01 | 0.242 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 5.726116e-01 | 0.242 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 5.726116e-01 | 0.242 | 0 | 0 |
| Interleukin-38 signaling | R-HSA-9007892 | 5.726116e-01 | 0.242 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 5.752681e-01 | 0.240 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 5.769868e-01 | 0.239 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 5.773354e-01 | 0.239 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 5.791521e-01 | 0.237 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 5.794832e-01 | 0.237 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 5.826895e-01 | 0.235 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 5.865806e-01 | 0.232 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 5.868927e-01 | 0.231 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 5.875044e-01 | 0.231 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 5.875044e-01 | 0.231 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 5.875044e-01 | 0.231 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 5.875044e-01 | 0.231 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 5.895196e-01 | 0.230 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 5.895196e-01 | 0.230 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 5.895196e-01 | 0.230 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 5.895196e-01 | 0.230 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 5.895196e-01 | 0.230 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 5.970734e-01 | 0.224 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 5.991871e-01 | 0.222 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 6.009796e-01 | 0.221 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 6.025221e-01 | 0.220 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 6.025221e-01 | 0.220 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 6.025221e-01 | 0.220 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 6.035698e-01 | 0.219 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 6.116566e-01 | 0.213 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 6.139133e-01 | 0.212 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 6.146406e-01 | 0.211 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 6.146406e-01 | 0.211 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 6.202900e-01 | 0.207 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 6.232069e-01 | 0.205 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 6.241811e-01 | 0.205 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 6.241811e-01 | 0.205 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 6.268439e-01 | 0.203 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 6.268439e-01 | 0.203 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 6.268439e-01 | 0.203 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 6.268439e-01 | 0.203 | 0 | 0 |
| Activation of AMPA receptors | R-HSA-399710 | 6.290804e-01 | 0.201 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 6.290804e-01 | 0.201 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 6.290804e-01 | 0.201 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 6.290804e-01 | 0.201 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 6.290804e-01 | 0.201 | 0 | 0 |
| Trafficking of myristoylated proteins to the cilium | R-HSA-5624138 | 6.290804e-01 | 0.201 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 6.290804e-01 | 0.201 | 0 | 0 |
| Inositol transporters | R-HSA-429593 | 6.290804e-01 | 0.201 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 6.290804e-01 | 0.201 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 6.290804e-01 | 0.201 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 6.290804e-01 | 0.201 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 6.290804e-01 | 0.201 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 6.304403e-01 | 0.200 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 6.322453e-01 | 0.199 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 6.322453e-01 | 0.199 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 6.322453e-01 | 0.199 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 6.322453e-01 | 0.199 | 0 | 0 |
| PKA activation | R-HSA-163615 | 6.322453e-01 | 0.199 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 6.330859e-01 | 0.199 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 6.330859e-01 | 0.199 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 6.330859e-01 | 0.199 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.361527e-01 | 0.196 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 6.379311e-01 | 0.195 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 6.392451e-01 | 0.194 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 6.392451e-01 | 0.194 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 6.392451e-01 | 0.194 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 6.392451e-01 | 0.194 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 6.392451e-01 | 0.194 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 6.416025e-01 | 0.193 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 6.418223e-01 | 0.193 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 6.425861e-01 | 0.192 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 6.444542e-01 | 0.191 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 6.448591e-01 | 0.191 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 6.465534e-01 | 0.189 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 6.504249e-01 | 0.187 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 6.504249e-01 | 0.187 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 6.515328e-01 | 0.186 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.603872e-01 | 0.180 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 6.603872e-01 | 0.180 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 6.603872e-01 | 0.180 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 6.614743e-01 | 0.179 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 6.614743e-01 | 0.179 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 6.614743e-01 | 0.179 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 6.614743e-01 | 0.179 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 6.614743e-01 | 0.179 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 6.614743e-01 | 0.179 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 6.614743e-01 | 0.179 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 6.614743e-01 | 0.179 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 6.620354e-01 | 0.179 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 6.634654e-01 | 0.178 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 6.652915e-01 | 0.177 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 6.675753e-01 | 0.175 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 6.721464e-01 | 0.173 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 6.721464e-01 | 0.173 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 6.732815e-01 | 0.172 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 6.749035e-01 | 0.171 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 6.780911e-01 | 0.169 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.780911e-01 | 0.169 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.780911e-01 | 0.169 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 6.780911e-01 | 0.169 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.780911e-01 | 0.169 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.780911e-01 | 0.169 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 6.780911e-01 | 0.169 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.780911e-01 | 0.169 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 6.780911e-01 | 0.169 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.780911e-01 | 0.169 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 6.780911e-01 | 0.169 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.780911e-01 | 0.169 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 6.780911e-01 | 0.169 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 6.780911e-01 | 0.169 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 6.780911e-01 | 0.169 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 6.780911e-01 | 0.169 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 6.780911e-01 | 0.169 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 6.780911e-01 | 0.169 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 6.780911e-01 | 0.169 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 6.803541e-01 | 0.167 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 6.865528e-01 | 0.163 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 6.865528e-01 | 0.163 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 6.869353e-01 | 0.163 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 6.869353e-01 | 0.163 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 6.869353e-01 | 0.163 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 6.869353e-01 | 0.163 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 6.887042e-01 | 0.162 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 6.887042e-01 | 0.162 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 6.929440e-01 | 0.159 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 6.934710e-01 | 0.159 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 6.934710e-01 | 0.159 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 6.934710e-01 | 0.159 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 6.934710e-01 | 0.159 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 6.934710e-01 | 0.159 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 6.934710e-01 | 0.159 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 6.934710e-01 | 0.159 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 6.934710e-01 | 0.159 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 7.072383e-01 | 0.150 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 7.084499e-01 | 0.150 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 7.084499e-01 | 0.150 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 7.101116e-01 | 0.149 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 7.101116e-01 | 0.149 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 7.102728e-01 | 0.149 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 7.118963e-01 | 0.148 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 7.118963e-01 | 0.148 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.127209e-01 | 0.147 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 7.131620e-01 | 0.147 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.158793e-01 | 0.145 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 7.206283e-01 | 0.142 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 7.206283e-01 | 0.142 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 7.206283e-01 | 0.142 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 7.206283e-01 | 0.142 | 0 | 0 |
| Defective CHST3 causes SEDCJD | R-HSA-3595172 | 7.206283e-01 | 0.142 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 7.206283e-01 | 0.142 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 7.206283e-01 | 0.142 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 7.206283e-01 | 0.142 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 7.206283e-01 | 0.142 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 7.206283e-01 | 0.142 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 7.206283e-01 | 0.142 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 7.206283e-01 | 0.142 | 0 | 0 |
| Leukotriene receptors | R-HSA-391906 | 7.206283e-01 | 0.142 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 7.225580e-01 | 0.141 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 7.229252e-01 | 0.141 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 7.229252e-01 | 0.141 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 7.229252e-01 | 0.141 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 7.229252e-01 | 0.141 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 7.229252e-01 | 0.141 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 7.274244e-01 | 0.138 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 7.274244e-01 | 0.138 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 7.274244e-01 | 0.138 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 7.293003e-01 | 0.137 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 7.293003e-01 | 0.137 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 7.314191e-01 | 0.136 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 7.352926e-01 | 0.134 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 7.442168e-01 | 0.128 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 7.452530e-01 | 0.128 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.452530e-01 | 0.128 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 7.452530e-01 | 0.128 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 7.453708e-01 | 0.128 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 7.457892e-01 | 0.127 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 7.469367e-01 | 0.127 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 7.471390e-01 | 0.127 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 7.499500e-01 | 0.125 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 7.499500e-01 | 0.125 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 7.499500e-01 | 0.125 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 7.499500e-01 | 0.125 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 7.499500e-01 | 0.125 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 7.499500e-01 | 0.125 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.499500e-01 | 0.125 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 7.499500e-01 | 0.125 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 7.499500e-01 | 0.125 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 7.562206e-01 | 0.121 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 7.567072e-01 | 0.121 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.571597e-01 | 0.121 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 7.571597e-01 | 0.121 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.571597e-01 | 0.121 | 0 | 0 |
| Defective CHSY1 causes TPBS | R-HSA-3595177 | 7.575467e-01 | 0.121 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 7.575467e-01 | 0.121 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.575467e-01 | 0.121 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.575467e-01 | 0.121 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 7.575467e-01 | 0.121 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 7.575467e-01 | 0.121 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 7.575467e-01 | 0.121 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 7.575467e-01 | 0.121 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 7.575467e-01 | 0.121 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 7.598319e-01 | 0.119 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 7.618069e-01 | 0.118 | 0 | 0 |
| Depurination | R-HSA-73927 | 7.623175e-01 | 0.118 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 7.675258e-01 | 0.115 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 7.675258e-01 | 0.115 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 7.675258e-01 | 0.115 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 7.681069e-01 | 0.115 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 7.746732e-01 | 0.111 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 7.746732e-01 | 0.111 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 7.746732e-01 | 0.111 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 7.746732e-01 | 0.111 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 7.756630e-01 | 0.110 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 7.785038e-01 | 0.109 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 7.785038e-01 | 0.109 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 7.785038e-01 | 0.109 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 7.849894e-01 | 0.105 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 7.889508e-01 | 0.103 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 7.893110e-01 | 0.103 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 7.893110e-01 | 0.103 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 7.895883e-01 | 0.103 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 7.895883e-01 | 0.103 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 7.895883e-01 | 0.103 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.895883e-01 | 0.103 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 7.895883e-01 | 0.103 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 7.895883e-01 | 0.103 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 7.895883e-01 | 0.103 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 7.895883e-01 | 0.103 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 7.895883e-01 | 0.103 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 7.895883e-01 | 0.103 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 7.895883e-01 | 0.103 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 7.938274e-01 | 0.100 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 7.938274e-01 | 0.100 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 7.938274e-01 | 0.100 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 7.964971e-01 | 0.099 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 7.966308e-01 | 0.099 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 7.972310e-01 | 0.098 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 7.972310e-01 | 0.098 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 7.972310e-01 | 0.098 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.972310e-01 | 0.098 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 8.013906e-01 | 0.096 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 8.014413e-01 | 0.096 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.047293e-01 | 0.094 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 8.047293e-01 | 0.094 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 8.072526e-01 | 0.093 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 8.082403e-01 | 0.092 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 8.091335e-01 | 0.092 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 8.140807e-01 | 0.089 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 8.140807e-01 | 0.089 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 8.140807e-01 | 0.089 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 8.140807e-01 | 0.089 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 8.159419e-01 | 0.088 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 8.167626e-01 | 0.088 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 8.167626e-01 | 0.088 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 8.167626e-01 | 0.088 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 8.173970e-01 | 0.088 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 8.173970e-01 | 0.088 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 8.173970e-01 | 0.088 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 8.173970e-01 | 0.088 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 8.173970e-01 | 0.088 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 8.173970e-01 | 0.088 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 8.173970e-01 | 0.088 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 8.173970e-01 | 0.088 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 8.173970e-01 | 0.088 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 8.176779e-01 | 0.087 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 8.177637e-01 | 0.087 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 8.177637e-01 | 0.087 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.177637e-01 | 0.087 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.177637e-01 | 0.087 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 8.262940e-01 | 0.083 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 8.303581e-01 | 0.081 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 8.311423e-01 | 0.080 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 8.348269e-01 | 0.078 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 8.348269e-01 | 0.078 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 8.348348e-01 | 0.078 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 8.348348e-01 | 0.078 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 8.348348e-01 | 0.078 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 8.364127e-01 | 0.078 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 8.364127e-01 | 0.078 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 8.364127e-01 | 0.078 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 8.364127e-01 | 0.078 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 8.370371e-01 | 0.077 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 8.398458e-01 | 0.076 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 8.415319e-01 | 0.075 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 8.415319e-01 | 0.075 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 8.415319e-01 | 0.075 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 8.415319e-01 | 0.075 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 8.415319e-01 | 0.075 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 8.415319e-01 | 0.075 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 8.453956e-01 | 0.073 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 8.453956e-01 | 0.073 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 8.453956e-01 | 0.073 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.453956e-01 | 0.073 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 8.454714e-01 | 0.073 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 8.504461e-01 | 0.070 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.508215e-01 | 0.070 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 8.533170e-01 | 0.069 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 8.533170e-01 | 0.069 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 8.533170e-01 | 0.069 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 8.533170e-01 | 0.069 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.555026e-01 | 0.068 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.555026e-01 | 0.068 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 8.582666e-01 | 0.066 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 8.592614e-01 | 0.066 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 8.605517e-01 | 0.065 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.611739e-01 | 0.065 | 0 | 0 |
| Presynaptic depolarization and calcium channel opening | R-HSA-112308 | 8.624780e-01 | 0.064 | 0 | 0 |
| FGFR2b ligand binding and activation | R-HSA-190377 | 8.624780e-01 | 0.064 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 8.624780e-01 | 0.064 | 0 | 0 |
| Conjugation of benzoate with glycine | R-HSA-177135 | 8.624780e-01 | 0.064 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 8.624780e-01 | 0.064 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 8.624780e-01 | 0.064 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 8.624780e-01 | 0.064 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 8.624780e-01 | 0.064 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 8.624780e-01 | 0.064 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 8.624780e-01 | 0.064 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 8.624780e-01 | 0.064 | 0 | 0 |
| Vitamin B1 (thiamin) metabolism | R-HSA-196819 | 8.624780e-01 | 0.064 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 8.624780e-01 | 0.064 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 8.649983e-01 | 0.063 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 8.675102e-01 | 0.062 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 8.686119e-01 | 0.061 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 8.686119e-01 | 0.061 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 8.686119e-01 | 0.061 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.686119e-01 | 0.061 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 8.689026e-01 | 0.061 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 8.689026e-01 | 0.061 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 8.689026e-01 | 0.061 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 8.689026e-01 | 0.061 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 8.709250e-01 | 0.060 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 8.720238e-01 | 0.059 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 8.720238e-01 | 0.059 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 8.788561e-01 | 0.056 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 8.788561e-01 | 0.056 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 8.806565e-01 | 0.055 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 8.806565e-01 | 0.055 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 8.806565e-01 | 0.055 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 8.806565e-01 | 0.055 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 8.806565e-01 | 0.055 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 8.806565e-01 | 0.055 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.806565e-01 | 0.055 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.806565e-01 | 0.055 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 8.824276e-01 | 0.054 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 8.837508e-01 | 0.054 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.877055e-01 | 0.052 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 8.881578e-01 | 0.052 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 8.887147e-01 | 0.051 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 8.897436e-01 | 0.051 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.904488e-01 | 0.050 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 8.948876e-01 | 0.048 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 8.964330e-01 | 0.047 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 8.964330e-01 | 0.047 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 8.964330e-01 | 0.047 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.964330e-01 | 0.047 | 0 | 0 |
| Conjugation of salicylate with glycine | R-HSA-177128 | 8.964330e-01 | 0.047 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.964330e-01 | 0.047 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 8.964330e-01 | 0.047 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 8.964330e-01 | 0.047 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 8.970410e-01 | 0.047 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 8.972105e-01 | 0.047 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 8.979813e-01 | 0.047 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 8.988811e-01 | 0.046 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 8.988811e-01 | 0.046 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 9.043641e-01 | 0.044 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.043772e-01 | 0.044 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.061090e-01 | 0.043 | 0 | 0 |
| Free fatty acid receptors | R-HSA-444209 | 9.061090e-01 | 0.043 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.061090e-01 | 0.043 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.061090e-01 | 0.043 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 9.069662e-01 | 0.042 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.088219e-01 | 0.042 | 0 | 0 |
| FGFR2c ligand binding and activation | R-HSA-190375 | 9.101247e-01 | 0.041 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 9.101247e-01 | 0.041 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 9.101247e-01 | 0.041 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 9.101247e-01 | 0.041 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 9.101247e-01 | 0.041 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 9.101247e-01 | 0.041 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 9.101247e-01 | 0.041 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 9.101247e-01 | 0.041 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 9.101247e-01 | 0.041 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.128132e-01 | 0.040 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 9.133784e-01 | 0.039 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.154236e-01 | 0.038 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 9.162014e-01 | 0.038 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 9.176482e-01 | 0.037 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.185727e-01 | 0.037 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.194625e-01 | 0.036 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.194625e-01 | 0.036 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.194625e-01 | 0.036 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 9.216127e-01 | 0.035 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.216384e-01 | 0.035 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 9.220071e-01 | 0.035 | 0 | 0 |
| Synthesis of IPs in the nucleus | R-HSA-1855191 | 9.220071e-01 | 0.035 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 9.220071e-01 | 0.035 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 9.220071e-01 | 0.035 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 9.220071e-01 | 0.035 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 9.220071e-01 | 0.035 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 9.220071e-01 | 0.035 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 9.220071e-01 | 0.035 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.238586e-01 | 0.034 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.252263e-01 | 0.034 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.252672e-01 | 0.034 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.252672e-01 | 0.034 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.252672e-01 | 0.034 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.259647e-01 | 0.033 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.291247e-01 | 0.032 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.291247e-01 | 0.032 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.291247e-01 | 0.032 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 9.293584e-01 | 0.032 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 9.323191e-01 | 0.030 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 9.323191e-01 | 0.030 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 9.323191e-01 | 0.030 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 9.323191e-01 | 0.030 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 9.323191e-01 | 0.030 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 9.323191e-01 | 0.030 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 9.323191e-01 | 0.030 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 9.323191e-01 | 0.030 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.334012e-01 | 0.030 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.334012e-01 | 0.030 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.334012e-01 | 0.030 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.334012e-01 | 0.030 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.334012e-01 | 0.030 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.348269e-01 | 0.029 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.357191e-01 | 0.029 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.357191e-01 | 0.029 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.359694e-01 | 0.029 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 9.404706e-01 | 0.027 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.406915e-01 | 0.027 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 9.406915e-01 | 0.027 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.406915e-01 | 0.027 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.406915e-01 | 0.027 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 9.412682e-01 | 0.026 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 9.412682e-01 | 0.026 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 9.412682e-01 | 0.026 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 9.412682e-01 | 0.026 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 9.412682e-01 | 0.026 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 9.412682e-01 | 0.026 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 9.412682e-01 | 0.026 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 9.412682e-01 | 0.026 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 9.412682e-01 | 0.026 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 9.414321e-01 | 0.026 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.414321e-01 | 0.026 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.421320e-01 | 0.026 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 9.421987e-01 | 0.026 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 9.421987e-01 | 0.026 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.421987e-01 | 0.026 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 9.445538e-01 | 0.025 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.466782e-01 | 0.024 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.472188e-01 | 0.024 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.472188e-01 | 0.024 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.478617e-01 | 0.023 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 9.478617e-01 | 0.023 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.490344e-01 | 0.023 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.490344e-01 | 0.023 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 9.490344e-01 | 0.023 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 9.490344e-01 | 0.023 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 9.490344e-01 | 0.023 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 9.490344e-01 | 0.023 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 9.490344e-01 | 0.023 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 9.490344e-01 | 0.023 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 9.490344e-01 | 0.023 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 9.490344e-01 | 0.023 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.493058e-01 | 0.023 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.501519e-01 | 0.022 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.509907e-01 | 0.022 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.514315e-01 | 0.022 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.514905e-01 | 0.022 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.519555e-01 | 0.021 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.530044e-01 | 0.021 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.530044e-01 | 0.021 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 9.530044e-01 | 0.021 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.530574e-01 | 0.021 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 9.530574e-01 | 0.021 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.530574e-01 | 0.021 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 9.539083e-01 | 0.020 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.542718e-01 | 0.020 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 9.542748e-01 | 0.020 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.546679e-01 | 0.020 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.557741e-01 | 0.020 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.557741e-01 | 0.020 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 9.557741e-01 | 0.020 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.576697e-01 | 0.019 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.576697e-01 | 0.019 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 9.579613e-01 | 0.019 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.582752e-01 | 0.019 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.582752e-01 | 0.019 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.582752e-01 | 0.019 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.589921e-01 | 0.018 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.597893e-01 | 0.018 | 0 | 0 |
| Activated point mutants of FGFR2 | R-HSA-2033519 | 9.616229e-01 | 0.017 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.616229e-01 | 0.017 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 9.616229e-01 | 0.017 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.618980e-01 | 0.017 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 9.618980e-01 | 0.017 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.629344e-01 | 0.016 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 9.629344e-01 | 0.016 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.629344e-01 | 0.016 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.632505e-01 | 0.016 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.636299e-01 | 0.016 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.657264e-01 | 0.015 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.657264e-01 | 0.015 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.657264e-01 | 0.015 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 9.666984e-01 | 0.015 | 0 | 0 |
| Conjugation of carboxylic acids | R-HSA-159424 | 9.666984e-01 | 0.015 | 0 | 0 |
| Amino Acid conjugation | R-HSA-156587 | 9.666984e-01 | 0.015 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 9.666984e-01 | 0.015 | 0 | 0 |
| Methionine salvage pathway | R-HSA-1237112 | 9.666984e-01 | 0.015 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 9.666984e-01 | 0.015 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.670913e-01 | 0.015 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 9.670913e-01 | 0.015 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.691558e-01 | 0.014 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.691899e-01 | 0.014 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 9.691899e-01 | 0.014 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.691899e-01 | 0.014 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.700842e-01 | 0.013 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.711030e-01 | 0.013 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.723203e-01 | 0.012 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.723203e-01 | 0.012 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.723203e-01 | 0.012 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.737874e-01 | 0.012 | 0 | 0 |
| FGFR2 ligand binding and activation | R-HSA-190241 | 9.749252e-01 | 0.011 | 0 | 0 |
| Phenylalanine metabolism | R-HSA-8964208 | 9.749252e-01 | 0.011 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 9.749252e-01 | 0.011 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 9.749252e-01 | 0.011 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.751476e-01 | 0.011 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.754121e-01 | 0.011 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.754121e-01 | 0.011 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.756843e-01 | 0.011 | 0 | 0 |
| CS-GAG biosynthesis | R-HSA-2022870 | 9.782421e-01 | 0.010 | 0 | 0 |
| Eicosanoids | R-HSA-211979 | 9.782421e-01 | 0.010 | 0 | 0 |
| Miscellaneous substrates | R-HSA-211958 | 9.782421e-01 | 0.010 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.782421e-01 | 0.010 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 9.782421e-01 | 0.010 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.782421e-01 | 0.010 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.782421e-01 | 0.010 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 9.787751e-01 | 0.009 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.796537e-01 | 0.009 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.796537e-01 | 0.009 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.796537e-01 | 0.009 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.796537e-01 | 0.009 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.799092e-01 | 0.009 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.800146e-01 | 0.009 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.806438e-01 | 0.008 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.811203e-01 | 0.008 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.813636e-01 | 0.008 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.814477e-01 | 0.008 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.818390e-01 | 0.008 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.819790e-01 | 0.008 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.819790e-01 | 0.008 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.820772e-01 | 0.008 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.831356e-01 | 0.007 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.836180e-01 | 0.007 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.836180e-01 | 0.007 | 0 | 0 |
| Fatty acids | R-HSA-211935 | 9.836180e-01 | 0.007 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 9.836180e-01 | 0.007 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.836180e-01 | 0.007 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.836180e-01 | 0.007 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.836180e-01 | 0.007 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.836180e-01 | 0.007 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.836180e-01 | 0.007 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.839633e-01 | 0.007 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.840453e-01 | 0.007 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.840453e-01 | 0.007 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 9.851845e-01 | 0.006 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.851845e-01 | 0.006 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.857853e-01 | 0.006 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.857853e-01 | 0.006 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.857853e-01 | 0.006 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 9.858805e-01 | 0.006 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.858805e-01 | 0.006 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.870106e-01 | 0.006 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 9.879390e-01 | 0.005 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.879390e-01 | 0.005 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.889547e-01 | 0.005 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.892981e-01 | 0.005 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.892981e-01 | 0.005 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 9.897046e-01 | 0.004 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.902060e-01 | 0.004 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.902362e-01 | 0.004 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 9.903269e-01 | 0.004 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.907142e-01 | 0.004 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 9.907142e-01 | 0.004 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.907142e-01 | 0.004 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.907142e-01 | 0.004 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.907142e-01 | 0.004 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.907142e-01 | 0.004 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.911739e-01 | 0.004 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.913721e-01 | 0.004 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.913721e-01 | 0.004 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.913721e-01 | 0.004 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.913721e-01 | 0.004 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.917799e-01 | 0.004 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.919430e-01 | 0.004 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 9.923784e-01 | 0.003 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.923784e-01 | 0.003 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 9.930093e-01 | 0.003 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.930093e-01 | 0.003 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.932248e-01 | 0.003 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.935680e-01 | 0.003 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.940584e-01 | 0.003 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 9.941541e-01 | 0.003 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.942170e-01 | 0.003 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.946559e-01 | 0.002 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.947373e-01 | 0.002 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.947564e-01 | 0.002 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.950655e-01 | 0.002 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.951288e-01 | 0.002 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 9.953310e-01 | 0.002 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.953738e-01 | 0.002 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.953800e-01 | 0.002 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.954338e-01 | 0.002 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.954338e-01 | 0.002 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.958073e-01 | 0.002 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.958073e-01 | 0.002 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.958573e-01 | 0.002 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 9.959196e-01 | 0.002 | 0 | 0 |
| Defective B3GALTL causes PpS | R-HSA-5083635 | 9.960383e-01 | 0.002 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.960383e-01 | 0.002 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.960383e-01 | 0.002 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.960472e-01 | 0.002 | 1 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.963093e-01 | 0.002 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 9.965627e-01 | 0.001 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.965627e-01 | 0.001 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.965627e-01 | 0.001 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.965627e-01 | 0.001 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.965627e-01 | 0.001 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.967112e-01 | 0.001 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.967112e-01 | 0.001 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.967132e-01 | 0.001 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.968283e-01 | 0.001 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.970178e-01 | 0.001 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 9.970178e-01 | 0.001 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.974126e-01 | 0.001 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.974126e-01 | 0.001 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.976415e-01 | 0.001 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.977552e-01 | 0.001 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.977552e-01 | 0.001 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.978306e-01 | 0.001 | 0 | 0 |
| O-glycosylation of TSR domain-containing proteins | R-HSA-5173214 | 9.980524e-01 | 0.001 | 0 | 0 |
| Ubiquinol biosynthesis | R-HSA-2142789 | 9.980524e-01 | 0.001 | 0 | 0 |
| Phenylalanine and tyrosine metabolism | R-HSA-8963691 | 9.980524e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.980524e-01 | 0.001 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.980524e-01 | 0.001 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.980524e-01 | 0.001 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.980524e-01 | 0.001 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.983103e-01 | 0.001 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.983103e-01 | 0.001 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.983179e-01 | 0.001 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.985341e-01 | 0.001 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.985341e-01 | 0.001 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.986969e-01 | 0.001 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.987282e-01 | 0.001 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.987282e-01 | 0.001 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.987367e-01 | 0.001 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.989112e-01 | 0.000 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.990428e-01 | 0.000 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.990428e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.991206e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.991529e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.991652e-01 | 0.000 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.992199e-01 | 0.000 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.993142e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.993721e-01 | 0.000 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.993750e-01 | 0.000 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.993750e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.993972e-01 | 0.000 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.994578e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.995345e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.995456e-01 | 0.000 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.995919e-01 | 0.000 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.995932e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.996125e-01 | 0.000 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.996460e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.996460e-01 | 0.000 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.996929e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.997139e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.997229e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.997229e-01 | 0.000 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.997336e-01 | 0.000 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.997618e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.998126e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.998229e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.998355e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.998355e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.998557e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.998662e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.998692e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.998734e-01 | 0.000 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.999026e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999108e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.999259e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.999343e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999343e-01 | 0.000 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.999357e-01 | 0.000 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.999357e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999379e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999473e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.999484e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999605e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.999636e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.999763e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999774e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.999794e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999847e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999847e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.999866e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.999866e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.999884e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.999899e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999917e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999950e-01 | 0.000 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.999950e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999952e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999960e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.999968e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999968e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999969e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999979e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999984e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999986e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999993e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999993e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999994e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.999995e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999995e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999996e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999997e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.999998e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999998e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999998e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.999999e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999999e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 1.000000e+00 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 1.000000e+00 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | -0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.110223e-16 | 15.955 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.110223e-16 | 15.955 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 2.220446e-16 | 15.654 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.554312e-15 | 14.808 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 6.206147e-14 | 13.207 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 6.050715e-14 | 13.218 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 2.658984e-13 | 12.575 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.849943e-13 | 12.545 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 2.070566e-12 | 11.684 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 6.014300e-12 | 11.221 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.200462e-11 | 10.921 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.609157e-11 | 10.793 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.609157e-11 | 10.793 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 3.743850e-11 | 10.427 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 4.101841e-11 | 10.387 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 7.645140e-11 | 10.117 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 7.430012e-11 | 10.129 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 8.252887e-11 | 10.083 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 1.068087e-10 | 9.971 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 1.478744e-10 | 9.830 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 1.672684e-10 | 9.777 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 1.727388e-10 | 9.763 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 2.059489e-10 | 9.686 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 4.540125e-10 | 9.343 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 5.097407e-10 | 9.293 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 6.208281e-10 | 9.207 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 6.696043e-10 | 9.174 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 8.338696e-10 | 9.079 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 1.121169e-09 | 8.950 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 2.075882e-09 | 8.683 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 2.601300e-09 | 8.585 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 3.317518e-09 | 8.479 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 3.429729e-09 | 8.465 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 3.963864e-09 | 8.402 | 1 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.732240e-09 | 8.325 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 4.657145e-09 | 8.332 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 6.123479e-09 | 8.213 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 6.143185e-09 | 8.212 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 6.162812e-09 | 8.210 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 6.781153e-09 | 8.169 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 7.178075e-09 | 8.144 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 6.942311e-09 | 8.158 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 8.234489e-09 | 8.084 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 8.234489e-09 | 8.084 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 8.018216e-09 | 8.096 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 8.148233e-09 | 8.089 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 8.274168e-09 | 8.082 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 8.470511e-09 | 8.072 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.431110e-09 | 8.074 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 9.167613e-09 | 8.038 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.087721e-08 | 7.963 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.093331e-08 | 7.961 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.766861e-08 | 7.753 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.835995e-08 | 7.736 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.919946e-08 | 7.717 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.112353e-08 | 7.675 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.550716e-08 | 7.593 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.754954e-08 | 7.560 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.956289e-08 | 7.529 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 3.389247e-08 | 7.470 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 3.451750e-08 | 7.462 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 3.567521e-08 | 7.448 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 3.619655e-08 | 7.441 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 5.076263e-08 | 7.294 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 4.906877e-08 | 7.309 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 5.780388e-08 | 7.238 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 7.966763e-08 | 7.099 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 9.856548e-08 | 7.006 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.045608e-07 | 6.981 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.115194e-07 | 6.953 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.115845e-07 | 6.952 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.342147e-07 | 6.872 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 1.409580e-07 | 6.851 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 2.498302e-07 | 6.602 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 2.805689e-07 | 6.552 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 2.805689e-07 | 6.552 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 2.906052e-07 | 6.537 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 2.991718e-07 | 6.524 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 3.012373e-07 | 6.521 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 3.161374e-07 | 6.500 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 3.185776e-07 | 6.497 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 3.459950e-07 | 6.461 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 3.896297e-07 | 6.409 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 4.044862e-07 | 6.393 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 4.153298e-07 | 6.382 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 4.255128e-07 | 6.371 | 1 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 4.637585e-07 | 6.334 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.538501e-07 | 6.185 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 7.298301e-07 | 6.137 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 7.298301e-07 | 6.137 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 8.658822e-07 | 6.063 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 1.029202e-06 | 5.987 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.205072e-06 | 5.919 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.223259e-06 | 5.912 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 1.227834e-06 | 5.911 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 1.254707e-06 | 5.901 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 1.271366e-06 | 5.896 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.302631e-06 | 5.885 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 1.353985e-06 | 5.868 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 1.353985e-06 | 5.868 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.411150e-06 | 5.850 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 1.538034e-06 | 5.813 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 2.025453e-06 | 5.693 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 2.039100e-06 | 5.691 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 2.094684e-06 | 5.679 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 2.238719e-06 | 5.650 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 2.346723e-06 | 5.630 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.555006e-06 | 5.593 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.672632e-06 | 5.573 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 3.026877e-06 | 5.519 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 3.051011e-06 | 5.516 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 3.092506e-06 | 5.510 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 3.159915e-06 | 5.500 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 3.368125e-06 | 5.473 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 3.202856e-06 | 5.494 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 3.278226e-06 | 5.484 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 3.818241e-06 | 5.418 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 4.481633e-06 | 5.349 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 4.710291e-06 | 5.327 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 5.115978e-06 | 5.291 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 5.115978e-06 | 5.291 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 5.116379e-06 | 5.291 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 5.119134e-06 | 5.291 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.432214e-06 | 5.265 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 5.483766e-06 | 5.261 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 5.952590e-06 | 5.225 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 6.061502e-06 | 5.217 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 6.274639e-06 | 5.202 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 6.375737e-06 | 5.195 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 6.773141e-06 | 5.169 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 7.804540e-06 | 5.108 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 8.503746e-06 | 5.070 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 8.736522e-06 | 5.059 | 0 | 0 |
| Protein folding | R-HSA-391251 | 8.798360e-06 | 5.056 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.296673e-05 | 4.887 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.332670e-05 | 4.875 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.326580e-05 | 4.877 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.337665e-05 | 4.874 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 1.574513e-05 | 4.803 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.679796e-05 | 4.775 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.694935e-05 | 4.771 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.735710e-05 | 4.761 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 2.049537e-05 | 4.688 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 2.299241e-05 | 4.638 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.449162e-05 | 4.611 | 1 | 1 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.449162e-05 | 4.611 | 1 | 1 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.449162e-05 | 4.611 | 1 | 1 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.449162e-05 | 4.611 | 1 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.356161e-05 | 4.628 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 2.668737e-05 | 4.574 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 2.734520e-05 | 4.563 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 3.136054e-05 | 4.504 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 3.427635e-05 | 4.465 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 3.491607e-05 | 4.457 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 3.659511e-05 | 4.437 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 3.820292e-05 | 4.418 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 4.045979e-05 | 4.393 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 4.089580e-05 | 4.388 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 4.101977e-05 | 4.387 | 0 | 0 |
| Kinesins | R-HSA-983189 | 4.154097e-05 | 4.382 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 4.732425e-05 | 4.325 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 4.497294e-05 | 4.347 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 5.854745e-05 | 4.232 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.059344e-05 | 4.218 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 6.182695e-05 | 4.209 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 6.274729e-05 | 4.202 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 7.164647e-05 | 4.145 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 7.263448e-05 | 4.139 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 7.296343e-05 | 4.137 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 7.650631e-05 | 4.116 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 7.817978e-05 | 4.107 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 7.982898e-05 | 4.098 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 8.398538e-05 | 4.076 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 8.411129e-05 | 4.075 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 8.725887e-05 | 4.059 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 8.726837e-05 | 4.059 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 8.999359e-05 | 4.046 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 9.983913e-05 | 4.001 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 9.502957e-05 | 4.022 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 9.661828e-05 | 4.015 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 9.983913e-05 | 4.001 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 9.983913e-05 | 4.001 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 9.541468e-05 | 4.020 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.006390e-04 | 3.997 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 1.050432e-04 | 3.979 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.062454e-04 | 3.974 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.105077e-04 | 3.957 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 1.117806e-04 | 3.952 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.197674e-04 | 3.922 | 1 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 1.225028e-04 | 3.912 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.227965e-04 | 3.911 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.333428e-04 | 3.875 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 1.371356e-04 | 3.863 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.446558e-04 | 3.840 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 1.491815e-04 | 3.826 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 1.503316e-04 | 3.823 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 1.542408e-04 | 3.812 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.551478e-04 | 3.809 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 1.562410e-04 | 3.806 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.592317e-04 | 3.798 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 1.706956e-04 | 3.768 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.746523e-04 | 3.758 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 2.385402e-04 | 3.622 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 2.385402e-04 | 3.622 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 2.198932e-04 | 3.658 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 2.153530e-04 | 3.667 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 2.151907e-04 | 3.667 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 2.249734e-04 | 3.648 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 2.145217e-04 | 3.669 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 2.131546e-04 | 3.671 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.584644e-04 | 3.588 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.584644e-04 | 3.588 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 2.646954e-04 | 3.577 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 2.646954e-04 | 3.577 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 2.652612e-04 | 3.576 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.663198e-04 | 3.575 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.700801e-04 | 3.569 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 2.753570e-04 | 3.560 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 2.864133e-04 | 3.543 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.864133e-04 | 3.543 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 2.918282e-04 | 3.535 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 2.951826e-04 | 3.530 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 3.012661e-04 | 3.521 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 3.061094e-04 | 3.514 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 3.131716e-04 | 3.504 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 3.200114e-04 | 3.495 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.250176e-04 | 3.488 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 3.377916e-04 | 3.471 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.449217e-04 | 3.462 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 3.551551e-04 | 3.450 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 3.959403e-04 | 3.402 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 3.996656e-04 | 3.398 | 0 | 0 |
| Immune System | R-HSA-168256 | 4.076762e-04 | 3.390 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 4.234894e-04 | 3.373 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 4.243956e-04 | 3.372 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 4.405366e-04 | 3.356 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 4.405366e-04 | 3.356 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 4.546738e-04 | 3.342 | 1 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 5.471021e-04 | 3.262 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 5.471021e-04 | 3.262 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 4.722217e-04 | 3.326 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 5.471021e-04 | 3.262 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 5.357377e-04 | 3.271 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 5.471021e-04 | 3.262 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 5.174644e-04 | 3.286 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 5.509989e-04 | 3.259 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 5.518537e-04 | 3.258 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 5.549816e-04 | 3.256 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 5.858806e-04 | 3.232 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 5.897542e-04 | 3.229 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 5.897542e-04 | 3.229 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 6.084606e-04 | 3.216 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 6.282989e-04 | 3.202 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 6.282989e-04 | 3.202 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 6.282989e-04 | 3.202 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 6.282989e-04 | 3.202 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 6.355130e-04 | 3.197 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 6.636202e-04 | 3.178 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 6.859293e-04 | 3.164 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 6.859293e-04 | 3.164 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 7.034036e-04 | 3.153 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.210137e-04 | 3.142 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 7.210137e-04 | 3.142 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 7.529338e-04 | 3.123 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 9.047861e-04 | 3.043 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 9.282165e-04 | 3.032 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 9.815545e-04 | 3.008 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 9.815545e-04 | 3.008 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.098230e-03 | 2.959 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.153606e-03 | 2.938 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.104588e-03 | 2.957 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.160107e-03 | 2.936 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 1.114092e-03 | 2.953 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.198231e-03 | 2.921 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.156133e-03 | 2.937 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 1.165970e-03 | 2.933 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.219307e-03 | 2.914 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.220070e-03 | 2.914 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.242860e-03 | 2.906 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 1.242860e-03 | 2.906 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 1.242860e-03 | 2.906 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.273600e-03 | 2.895 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 1.347228e-03 | 2.871 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.382313e-03 | 2.859 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 1.411141e-03 | 2.850 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 1.444152e-03 | 2.840 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.444152e-03 | 2.840 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.444731e-03 | 2.840 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.468506e-03 | 2.833 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.496139e-03 | 2.825 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.502964e-03 | 2.823 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.538328e-03 | 2.813 | 0 | 0 |
| S Phase | R-HSA-69242 | 1.564679e-03 | 2.806 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.618341e-03 | 2.791 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 1.654880e-03 | 2.781 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 1.677500e-03 | 2.775 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.677500e-03 | 2.775 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 1.677500e-03 | 2.775 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 1.708744e-03 | 2.767 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.744119e-03 | 2.758 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.744119e-03 | 2.758 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.790513e-03 | 2.747 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 1.817828e-03 | 2.740 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 1.826371e-03 | 2.738 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.868303e-03 | 2.729 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.944230e-03 | 2.711 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.944230e-03 | 2.711 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 2.021135e-03 | 2.694 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 2.057287e-03 | 2.687 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 2.169439e-03 | 2.664 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 2.204332e-03 | 2.657 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.234653e-03 | 2.651 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 2.344294e-03 | 2.630 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 2.344294e-03 | 2.630 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 2.356969e-03 | 2.628 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 2.356969e-03 | 2.628 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 2.359277e-03 | 2.627 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.385311e-03 | 2.622 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 2.418702e-03 | 2.616 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 2.418702e-03 | 2.616 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 2.742098e-03 | 2.562 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 2.612626e-03 | 2.583 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 2.688276e-03 | 2.571 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 2.643364e-03 | 2.578 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 2.605641e-03 | 2.584 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 2.989712e-03 | 2.524 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 2.557779e-03 | 2.592 | 0 | 0 |
| Translation | R-HSA-72766 | 2.619433e-03 | 2.582 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.517778e-03 | 2.599 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 2.522286e-03 | 2.598 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.517778e-03 | 2.599 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 3.043498e-03 | 2.517 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 3.150379e-03 | 2.502 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 3.254886e-03 | 2.487 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 3.254886e-03 | 2.487 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 3.328236e-03 | 2.478 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 3.382551e-03 | 2.471 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 3.382551e-03 | 2.471 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 3.382551e-03 | 2.471 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 3.382551e-03 | 2.471 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 3.480819e-03 | 2.458 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 3.480819e-03 | 2.458 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 3.554410e-03 | 2.449 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 3.650982e-03 | 2.438 | 1 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.732672e-03 | 2.428 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 3.815275e-03 | 2.418 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 3.857143e-03 | 2.414 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 4.238889e-03 | 2.373 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 4.287714e-03 | 2.368 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.287714e-03 | 2.368 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 4.562190e-03 | 2.341 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 4.562190e-03 | 2.341 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 4.606502e-03 | 2.337 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 4.606502e-03 | 2.337 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 4.606502e-03 | 2.337 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 4.671152e-03 | 2.331 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 4.671152e-03 | 2.331 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 4.747138e-03 | 2.324 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 4.810753e-03 | 2.318 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 5.065961e-03 | 2.295 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 5.154019e-03 | 2.288 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 5.154019e-03 | 2.288 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 5.154019e-03 | 2.288 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 5.378513e-03 | 2.269 | 1 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 5.439358e-03 | 2.264 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 5.448881e-03 | 2.264 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 5.540750e-03 | 2.256 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 5.575976e-03 | 2.254 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 5.622358e-03 | 2.250 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 5.622358e-03 | 2.250 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 5.664536e-03 | 2.247 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 5.809218e-03 | 2.236 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 5.857358e-03 | 2.232 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 5.888286e-03 | 2.230 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 6.009331e-03 | 2.221 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 6.009331e-03 | 2.221 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 6.128760e-03 | 2.213 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 6.137872e-03 | 2.212 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 6.137872e-03 | 2.212 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 6.137872e-03 | 2.212 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 6.137872e-03 | 2.212 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 6.137872e-03 | 2.212 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 6.245345e-03 | 2.204 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 6.251112e-03 | 2.204 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 6.523849e-03 | 2.185 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 6.531899e-03 | 2.185 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 6.728379e-03 | 2.172 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 6.807975e-03 | 2.167 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 6.970284e-03 | 2.157 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 6.970284e-03 | 2.157 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 6.972372e-03 | 2.157 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 7.095094e-03 | 2.149 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 7.132331e-03 | 2.147 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 7.478871e-03 | 2.126 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 7.987595e-03 | 2.098 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 9.738226e-03 | 2.012 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.738226e-03 | 2.012 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 9.344880e-03 | 2.029 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 8.961839e-03 | 2.048 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 8.487272e-03 | 2.071 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 7.987595e-03 | 2.098 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 9.256900e-03 | 2.034 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 8.754786e-03 | 2.058 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 8.754786e-03 | 2.058 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 8.570321e-03 | 2.067 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 8.487272e-03 | 2.071 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 9.296706e-03 | 2.032 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 8.487272e-03 | 2.071 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 9.256900e-03 | 2.034 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 9.254282e-03 | 2.034 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 7.987595e-03 | 2.098 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 9.254282e-03 | 2.034 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 8.487272e-03 | 2.071 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.449866e-03 | 2.025 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.940794e-03 | 2.049 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 9.738226e-03 | 2.012 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 8.251668e-03 | 2.083 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 7.478871e-03 | 2.126 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 7.478871e-03 | 2.126 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 7.478871e-03 | 2.126 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 8.885350e-03 | 2.051 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.800669e-03 | 2.009 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.014217e-02 | 1.994 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 1.022068e-02 | 1.991 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.022068e-02 | 1.991 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 1.022068e-02 | 1.991 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 1.022068e-02 | 1.991 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 1.022068e-02 | 1.991 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 1.022068e-02 | 1.991 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 1.034376e-02 | 1.985 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 1.034376e-02 | 1.985 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.038493e-02 | 1.984 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.038493e-02 | 1.984 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.038493e-02 | 1.984 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 1.038493e-02 | 1.984 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 1.066148e-02 | 1.972 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 1.066148e-02 | 1.972 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 1.078219e-02 | 1.967 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.078219e-02 | 1.967 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 1.113313e-02 | 1.953 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 1.139523e-02 | 1.943 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.210976e-02 | 1.917 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 1.210976e-02 | 1.917 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.244921e-02 | 1.905 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.258129e-02 | 1.900 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 1.286447e-02 | 1.891 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.296249e-02 | 1.887 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 1.319120e-02 | 1.880 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.329619e-02 | 1.876 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.330586e-02 | 1.876 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.369563e-02 | 1.863 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.371595e-02 | 1.863 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 1.401060e-02 | 1.854 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.436039e-02 | 1.843 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 1.454286e-02 | 1.837 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 1.491641e-02 | 1.826 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.491641e-02 | 1.826 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 1.539932e-02 | 1.812 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 1.551439e-02 | 1.809 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.560002e-02 | 1.807 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 1.560002e-02 | 1.807 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.560002e-02 | 1.807 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 1.564859e-02 | 1.806 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.575914e-02 | 1.802 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 1.577376e-02 | 1.802 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.577376e-02 | 1.802 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 1.577376e-02 | 1.802 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 1.577376e-02 | 1.802 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 1.595362e-02 | 1.797 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 1.595362e-02 | 1.797 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 1.692079e-02 | 1.772 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 1.692079e-02 | 1.772 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 1.709694e-02 | 1.767 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.780112e-02 | 1.750 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.797450e-02 | 1.745 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 1.858952e-02 | 1.731 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 1.859754e-02 | 1.731 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 1.873264e-02 | 1.727 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 1.909975e-02 | 1.719 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.952045e-02 | 1.710 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.952045e-02 | 1.710 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.952045e-02 | 1.710 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 1.971422e-02 | 1.705 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.988793e-02 | 1.701 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.988793e-02 | 1.701 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 1.990397e-02 | 1.701 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 1.990397e-02 | 1.701 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.990397e-02 | 1.701 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 1.996559e-02 | 1.700 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 2.032313e-02 | 1.692 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 2.032313e-02 | 1.692 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 2.098929e-02 | 1.678 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 2.147400e-02 | 1.668 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 2.147400e-02 | 1.668 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 2.147400e-02 | 1.668 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 2.147400e-02 | 1.668 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 2.197409e-02 | 1.658 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 2.197409e-02 | 1.658 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.200489e-02 | 1.657 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.333715e-02 | 1.477 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 2.960590e-02 | 1.529 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.828753e-02 | 1.548 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 2.398768e-02 | 1.620 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.359452e-02 | 1.627 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.820220e-02 | 1.550 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 3.336641e-02 | 1.477 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 2.302411e-02 | 1.638 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.317043e-02 | 1.635 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 3.192937e-02 | 1.496 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 3.021473e-02 | 1.520 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 3.021473e-02 | 1.520 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 2.574168e-02 | 1.589 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 3.339592e-02 | 1.476 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 3.339592e-02 | 1.476 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 3.339592e-02 | 1.476 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 3.181158e-02 | 1.497 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 2.944936e-02 | 1.531 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 3.307077e-02 | 1.481 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 3.339592e-02 | 1.476 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 2.960590e-02 | 1.529 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 2.820220e-02 | 1.550 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 3.192937e-02 | 1.496 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 3.156302e-02 | 1.501 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 2.725594e-02 | 1.565 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 2.647306e-02 | 1.577 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 3.339592e-02 | 1.476 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.556415e-02 | 1.592 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.575989e-02 | 1.589 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.575989e-02 | 1.589 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.333715e-02 | 1.477 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 2.274840e-02 | 1.643 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 2.629413e-02 | 1.580 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 2.317043e-02 | 1.635 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 2.317043e-02 | 1.635 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 2.828753e-02 | 1.548 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 3.336641e-02 | 1.477 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 3.336641e-02 | 1.477 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 2.244106e-02 | 1.649 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 2.932351e-02 | 1.533 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 2.828753e-02 | 1.548 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 2.317043e-02 | 1.635 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.274840e-02 | 1.643 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 2.360506e-02 | 1.627 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.862133e-02 | 1.543 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 2.961555e-02 | 1.528 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 3.336641e-02 | 1.477 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 2.961555e-02 | 1.528 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 2.302411e-02 | 1.638 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 2.557687e-02 | 1.592 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 2.862133e-02 | 1.543 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 2.862133e-02 | 1.543 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 3.181158e-02 | 1.497 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.359452e-02 | 1.627 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 3.176455e-02 | 1.498 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 3.233699e-02 | 1.490 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.359452e-02 | 1.627 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 2.302411e-02 | 1.638 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 3.340202e-02 | 1.476 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 3.427709e-02 | 1.465 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.441488e-02 | 1.463 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 3.441488e-02 | 1.463 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 3.441488e-02 | 1.463 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 3.441488e-02 | 1.463 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 3.441488e-02 | 1.463 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 3.460750e-02 | 1.461 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 3.549719e-02 | 1.450 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 3.601124e-02 | 1.444 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.601124e-02 | 1.444 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 3.601124e-02 | 1.444 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 3.624881e-02 | 1.441 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 3.680460e-02 | 1.434 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 3.741285e-02 | 1.427 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 3.741285e-02 | 1.427 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 3.779263e-02 | 1.423 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 3.789422e-02 | 1.421 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 3.893340e-02 | 1.410 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 3.910632e-02 | 1.408 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 3.910632e-02 | 1.408 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 3.933307e-02 | 1.405 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.970432e-02 | 1.401 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 4.045449e-02 | 1.393 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 4.106491e-02 | 1.387 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 4.106491e-02 | 1.387 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 4.106491e-02 | 1.387 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 4.128282e-02 | 1.384 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 4.128282e-02 | 1.384 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 4.174025e-02 | 1.379 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 4.174025e-02 | 1.379 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 4.174025e-02 | 1.379 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 4.319500e-02 | 1.365 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 4.344466e-02 | 1.362 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 4.383186e-02 | 1.358 | 1 | 1 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 4.383186e-02 | 1.358 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 4.383186e-02 | 1.358 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 4.383186e-02 | 1.358 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 4.383186e-02 | 1.358 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 4.383186e-02 | 1.358 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 4.434523e-02 | 1.353 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 4.434523e-02 | 1.353 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 4.526739e-02 | 1.344 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 4.526739e-02 | 1.344 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 4.543722e-02 | 1.343 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 4.639267e-02 | 1.334 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 4.639267e-02 | 1.334 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 4.639267e-02 | 1.334 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 4.639267e-02 | 1.334 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 4.911956e-02 | 1.309 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 5.064169e-02 | 1.295 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 5.130693e-02 | 1.290 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 5.130693e-02 | 1.290 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 5.206635e-02 | 1.283 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 5.480425e-02 | 1.261 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 5.492932e-02 | 1.260 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 5.574950e-02 | 1.254 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 5.574950e-02 | 1.254 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 5.574950e-02 | 1.254 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 5.670106e-02 | 1.246 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 5.670106e-02 | 1.246 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 5.670106e-02 | 1.246 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 5.749924e-02 | 1.240 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 5.783077e-02 | 1.238 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 5.783077e-02 | 1.238 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 5.881150e-02 | 1.231 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 5.900201e-02 | 1.229 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 6.089206e-02 | 1.215 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 6.089206e-02 | 1.215 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 6.089206e-02 | 1.215 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 6.236854e-02 | 1.205 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 6.236854e-02 | 1.205 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 6.277531e-02 | 1.202 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 6.643971e-02 | 1.178 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 6.709728e-02 | 1.173 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 6.709728e-02 | 1.173 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 6.709728e-02 | 1.173 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 6.709728e-02 | 1.173 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 6.709728e-02 | 1.173 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 6.763171e-02 | 1.170 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 6.806832e-02 | 1.167 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 6.806832e-02 | 1.167 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 6.838393e-02 | 1.165 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 6.838393e-02 | 1.165 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 6.838393e-02 | 1.165 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 6.838393e-02 | 1.165 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 6.872003e-02 | 1.163 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.043979e-02 | 1.152 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 7.043979e-02 | 1.152 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 7.043979e-02 | 1.152 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 7.043979e-02 | 1.152 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.043979e-02 | 1.152 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 7.150526e-02 | 1.146 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 7.235011e-02 | 1.141 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 7.308427e-02 | 1.136 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 7.429328e-02 | 1.129 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 7.458190e-02 | 1.127 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 7.475007e-02 | 1.126 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 7.880842e-02 | 1.103 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 7.880842e-02 | 1.103 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 7.964888e-02 | 1.099 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 7.964888e-02 | 1.099 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 7.964888e-02 | 1.099 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 7.973793e-02 | 1.098 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 7.995210e-02 | 1.097 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 7.995210e-02 | 1.097 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 8.034877e-02 | 1.095 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 8.034877e-02 | 1.095 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 8.034877e-02 | 1.095 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 8.034877e-02 | 1.095 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 8.042882e-02 | 1.095 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 8.042882e-02 | 1.095 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 8.161060e-02 | 1.088 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 8.198232e-02 | 1.086 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 8.198232e-02 | 1.086 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 8.198232e-02 | 1.086 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 8.198232e-02 | 1.086 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 8.465506e-02 | 1.072 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 8.480559e-02 | 1.072 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 8.504954e-02 | 1.070 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 8.620981e-02 | 1.064 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 8.620981e-02 | 1.064 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 8.620981e-02 | 1.064 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 8.692817e-02 | 1.061 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 8.692817e-02 | 1.061 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 8.768067e-02 | 1.057 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 8.768067e-02 | 1.057 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 8.768067e-02 | 1.057 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 8.768067e-02 | 1.057 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 8.768067e-02 | 1.057 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 8.768067e-02 | 1.057 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 8.768067e-02 | 1.057 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 8.768067e-02 | 1.057 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.722506e-01 | 0.764 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.722506e-01 | 0.764 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.722506e-01 | 0.764 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.722506e-01 | 0.764 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 1.722506e-01 | 0.764 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.722506e-01 | 0.764 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 1.722506e-01 | 0.764 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.722506e-01 | 0.764 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.722506e-01 | 0.764 | 0 | 0 |
| RPIA deficiency: failed conversion of R5P to RU5P | R-HSA-5659996 | 1.722506e-01 | 0.764 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.722506e-01 | 0.764 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 1.722506e-01 | 0.764 | 0 | 0 |
| RPIA deficiency: failed conversion of RU5P to R5P | R-HSA-6791461 | 1.722506e-01 | 0.764 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.722506e-01 | 0.764 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.111651e-01 | 0.954 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.111651e-01 | 0.954 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.425531e-01 | 0.846 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 1.425531e-01 | 0.846 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.425531e-01 | 0.846 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.425531e-01 | 0.846 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 1.425531e-01 | 0.846 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 1.425531e-01 | 0.846 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.425531e-01 | 0.846 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.425531e-01 | 0.846 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 1.064991e-01 | 0.973 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.755118e-01 | 0.756 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 1.755118e-01 | 0.756 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 1.267300e-01 | 0.897 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.267300e-01 | 0.897 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 9.327490e-02 | 1.030 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 1.079229e-01 | 0.967 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 9.111985e-02 | 1.040 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 1.235319e-01 | 0.908 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 1.400341e-01 | 0.854 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 1.157020e-01 | 0.937 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 9.618294e-02 | 1.017 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 1.573562e-01 | 0.803 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 9.781350e-02 | 1.010 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 1.577220e-01 | 0.802 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 1.171930e-01 | 0.931 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.729479e-01 | 0.762 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 1.545023e-01 | 0.811 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 1.384061e-01 | 0.859 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 1.613397e-01 | 0.792 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 9.823758e-02 | 1.008 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 1.748168e-01 | 0.757 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 1.613397e-01 | 0.792 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 1.613397e-01 | 0.792 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 8.853979e-02 | 1.053 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 1.171930e-01 | 0.931 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 1.754211e-01 | 0.756 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.754211e-01 | 0.756 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 8.933885e-02 | 1.049 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 1.267300e-01 | 0.897 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 1.340087e-01 | 0.873 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.340087e-01 | 0.873 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 1.755118e-01 | 0.756 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 1.079229e-01 | 0.967 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.545023e-01 | 0.811 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 1.037360e-01 | 0.984 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 1.677105e-01 | 0.775 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 1.178746e-01 | 0.929 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 1.689085e-01 | 0.772 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.064991e-01 | 0.973 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 1.030454e-01 | 0.987 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 1.417767e-01 | 0.848 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.781350e-02 | 1.010 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 1.267300e-01 | 0.897 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 1.178746e-01 | 0.929 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 1.082721e-01 | 0.965 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.072682e-01 | 0.970 | 0 | 0 |
| Activation and oligomerization of BAK protein | R-HSA-111452 | 1.722506e-01 | 0.764 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 1.755118e-01 | 0.756 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.747577e-02 | 1.011 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 1.340087e-01 | 0.873 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 1.430780e-01 | 0.844 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 1.494476e-01 | 0.826 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 1.355973e-01 | 0.868 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 9.327490e-02 | 1.030 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 9.618294e-02 | 1.017 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 1.729479e-01 | 0.762 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 1.118557e-01 | 0.951 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 8.853979e-02 | 1.053 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 1.734088e-01 | 0.761 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.157020e-01 | 0.937 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 1.722506e-01 | 0.764 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.722506e-01 | 0.764 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.722506e-01 | 0.764 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.111651e-01 | 0.954 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 1.425531e-01 | 0.846 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.707414e-01 | 0.768 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 1.157020e-01 | 0.937 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 1.573562e-01 | 0.803 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 1.754211e-01 | 0.756 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.653559e-01 | 0.782 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 1.129914e-01 | 0.947 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 1.240201e-01 | 0.907 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.417767e-01 | 0.848 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 1.510738e-01 | 0.821 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 1.072682e-01 | 0.970 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 1.430780e-01 | 0.844 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 9.618294e-02 | 1.017 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.400341e-01 | 0.854 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 1.574614e-01 | 0.803 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 1.064991e-01 | 0.973 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.574614e-01 | 0.803 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.140078e-01 | 0.943 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 1.545527e-01 | 0.811 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 1.734088e-01 | 0.761 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 1.755118e-01 | 0.756 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 1.390657e-01 | 0.857 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.781350e-02 | 1.010 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.384061e-01 | 0.859 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 1.108142e-01 | 0.955 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 1.440994e-01 | 0.841 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 1.289941e-01 | 0.889 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 1.167913e-01 | 0.933 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 1.425531e-01 | 0.846 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 1.282778e-01 | 0.892 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.675305e-01 | 0.776 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 1.030454e-01 | 0.987 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 1.755118e-01 | 0.756 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 1.290582e-01 | 0.889 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.430780e-01 | 0.844 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 1.030454e-01 | 0.987 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 1.430780e-01 | 0.844 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 1.546063e-01 | 0.811 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 1.072682e-01 | 0.970 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 1.425531e-01 | 0.846 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.157020e-01 | 0.937 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 1.157020e-01 | 0.937 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 1.203176e-01 | 0.920 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.781350e-02 | 1.010 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 8.933885e-02 | 1.049 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 1.340087e-01 | 0.873 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.400341e-01 | 0.854 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 1.690042e-01 | 0.772 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 1.235319e-01 | 0.908 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.262421e-02 | 1.033 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 1.040554e-01 | 0.983 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 1.220629e-01 | 0.913 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.235319e-01 | 0.908 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.573562e-01 | 0.803 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 1.425531e-01 | 0.846 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 1.764954e-01 | 0.753 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 1.776166e-01 | 0.751 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.782556e-01 | 0.749 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 1.858533e-01 | 0.731 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 1.858533e-01 | 0.731 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 1.858533e-01 | 0.731 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 1.858533e-01 | 0.731 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 1.865207e-01 | 0.729 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 1.865207e-01 | 0.729 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 1.882531e-01 | 0.725 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 1.885381e-01 | 0.725 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.887107e-01 | 0.724 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 1.887107e-01 | 0.724 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 1.941493e-01 | 0.712 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 1.941493e-01 | 0.712 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 1.941770e-01 | 0.712 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.941770e-01 | 0.712 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.954609e-01 | 0.709 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 1.954609e-01 | 0.709 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 1.965493e-01 | 0.707 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 1.981760e-01 | 0.703 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 2.028338e-01 | 0.693 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.049636e-01 | 0.688 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.049636e-01 | 0.688 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 2.049636e-01 | 0.688 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 2.087277e-01 | 0.680 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 2.087277e-01 | 0.680 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.095030e-01 | 0.679 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 2.095030e-01 | 0.679 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 2.095030e-01 | 0.679 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 2.095030e-01 | 0.679 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 2.099424e-01 | 0.678 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 2.106252e-01 | 0.676 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 2.117792e-01 | 0.674 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 2.117835e-01 | 0.674 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 2.134597e-01 | 0.671 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 2.134597e-01 | 0.671 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 2.134597e-01 | 0.671 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 2.178392e-01 | 0.662 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 2.178392e-01 | 0.662 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 2.183417e-01 | 0.661 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 2.186887e-01 | 0.660 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 2.193773e-01 | 0.659 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 2.220411e-01 | 0.654 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 2.247855e-01 | 0.648 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 2.252238e-01 | 0.647 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 2.332710e-01 | 0.632 | 0 | 0 |
| Disease | R-HSA-1643685 | 2.342169e-01 | 0.630 | 1 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 2.362264e-01 | 0.627 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 2.367773e-01 | 0.626 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 2.367773e-01 | 0.626 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 2.367773e-01 | 0.626 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 2.373474e-01 | 0.625 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 2.373474e-01 | 0.625 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 2.373474e-01 | 0.625 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 2.373474e-01 | 0.625 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 2.373474e-01 | 0.625 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 2.387458e-01 | 0.622 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 2.389494e-01 | 0.622 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 2.389494e-01 | 0.622 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 2.430753e-01 | 0.614 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 2.430753e-01 | 0.614 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 2.430753e-01 | 0.614 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 2.440728e-01 | 0.612 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.440728e-01 | 0.612 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.440728e-01 | 0.612 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 2.440728e-01 | 0.612 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 2.440728e-01 | 0.612 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 2.440728e-01 | 0.612 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 2.440728e-01 | 0.612 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 2.455473e-01 | 0.610 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 2.469142e-01 | 0.607 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.469142e-01 | 0.607 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.469142e-01 | 0.607 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.469142e-01 | 0.607 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.469142e-01 | 0.607 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.469142e-01 | 0.607 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.469142e-01 | 0.607 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.469142e-01 | 0.607 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 2.469142e-01 | 0.607 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 2.469142e-01 | 0.607 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 2.507031e-01 | 0.601 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 2.525413e-01 | 0.598 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 2.529358e-01 | 0.597 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 2.535024e-01 | 0.596 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.535024e-01 | 0.596 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 2.561764e-01 | 0.591 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 2.561764e-01 | 0.591 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 2.565946e-01 | 0.591 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 2.565946e-01 | 0.591 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 2.565946e-01 | 0.591 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 2.576082e-01 | 0.589 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 2.600440e-01 | 0.585 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 2.625385e-01 | 0.581 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 2.639610e-01 | 0.578 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.664360e-01 | 0.574 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 2.682260e-01 | 0.571 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.682260e-01 | 0.571 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 2.682260e-01 | 0.571 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 2.711502e-01 | 0.567 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 2.711502e-01 | 0.567 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 2.711502e-01 | 0.567 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 2.739006e-01 | 0.562 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.739752e-01 | 0.562 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 2.740746e-01 | 0.562 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 2.740746e-01 | 0.562 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 2.740746e-01 | 0.562 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 2.740746e-01 | 0.562 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 2.740746e-01 | 0.562 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 2.740746e-01 | 0.562 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 2.784966e-01 | 0.555 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 2.788405e-01 | 0.555 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 2.788405e-01 | 0.555 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 2.788405e-01 | 0.555 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 2.788405e-01 | 0.555 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 2.800306e-01 | 0.553 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 2.815904e-01 | 0.550 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 2.871034e-01 | 0.542 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 2.871034e-01 | 0.542 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 2.871034e-01 | 0.542 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 2.911748e-01 | 0.536 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 2.918692e-01 | 0.535 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 2.936515e-01 | 0.532 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 2.936515e-01 | 0.532 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 2.936515e-01 | 0.532 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 2.936515e-01 | 0.532 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 2.936515e-01 | 0.532 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 2.936515e-01 | 0.532 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.936515e-01 | 0.532 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 2.948365e-01 | 0.530 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 2.949104e-01 | 0.530 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 2.949104e-01 | 0.530 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.949104e-01 | 0.530 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 2.949104e-01 | 0.530 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 2.985681e-01 | 0.525 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.991379e-01 | 0.524 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 2.991379e-01 | 0.524 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 3.113723e-01 | 0.507 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 3.134896e-01 | 0.504 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 3.134896e-01 | 0.504 | 0 | 0 |
| Hypusine synthesis from eIF5A-lysine | R-HSA-204626 | 3.134896e-01 | 0.504 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 3.134896e-01 | 0.504 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 3.134896e-01 | 0.504 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 3.134896e-01 | 0.504 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 3.134896e-01 | 0.504 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 3.134896e-01 | 0.504 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 3.134896e-01 | 0.504 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 3.134896e-01 | 0.504 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 3.134896e-01 | 0.504 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.134896e-01 | 0.504 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.148470e-01 | 0.502 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 3.148470e-01 | 0.502 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.148470e-01 | 0.502 | 0 | 0 |
| Defective AHCY causes HMAHCHD | R-HSA-5578997 | 3.148470e-01 | 0.502 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 3.148470e-01 | 0.502 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.148470e-01 | 0.502 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.148470e-01 | 0.502 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 3.148470e-01 | 0.502 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 3.148470e-01 | 0.502 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.148470e-01 | 0.502 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 3.148470e-01 | 0.502 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 3.148470e-01 | 0.502 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.148470e-01 | 0.502 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 3.192196e-01 | 0.496 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.192196e-01 | 0.496 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 3.192196e-01 | 0.496 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 3.192196e-01 | 0.496 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 3.192196e-01 | 0.496 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 3.192196e-01 | 0.496 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 3.192196e-01 | 0.496 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.232225e-01 | 0.490 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 3.283468e-01 | 0.484 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 3.283468e-01 | 0.484 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 3.283468e-01 | 0.484 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 3.290346e-01 | 0.483 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 3.302588e-01 | 0.481 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 3.359803e-01 | 0.474 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 3.359803e-01 | 0.474 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 3.370772e-01 | 0.472 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 3.370772e-01 | 0.472 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.409160e-01 | 0.467 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 3.409160e-01 | 0.467 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 3.448087e-01 | 0.462 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 3.448273e-01 | 0.462 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.477588e-01 | 0.459 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 3.477588e-01 | 0.459 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 3.477588e-01 | 0.459 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 3.477588e-01 | 0.459 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 3.477588e-01 | 0.459 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.477588e-01 | 0.459 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 3.477588e-01 | 0.459 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 3.582690e-01 | 0.446 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 3.582690e-01 | 0.446 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 3.703079e-01 | 0.431 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 3.703079e-01 | 0.431 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 3.703079e-01 | 0.431 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 3.719625e-01 | 0.430 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 3.766556e-01 | 0.424 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.766556e-01 | 0.424 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 3.766556e-01 | 0.424 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.766556e-01 | 0.424 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 3.766556e-01 | 0.424 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 3.766556e-01 | 0.424 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 3.766556e-01 | 0.424 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 3.766556e-01 | 0.424 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 3.766556e-01 | 0.424 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 3.794461e-01 | 0.421 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 3.794461e-01 | 0.421 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 3.794461e-01 | 0.421 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 3.796762e-01 | 0.421 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 3.796762e-01 | 0.421 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 3.814347e-01 | 0.419 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 3.814347e-01 | 0.419 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 3.814347e-01 | 0.419 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 3.814347e-01 | 0.419 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.814347e-01 | 0.419 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.814347e-01 | 0.419 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 3.837224e-01 | 0.416 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 3.837224e-01 | 0.416 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 3.955976e-01 | 0.403 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.956171e-01 | 0.403 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 3.956171e-01 | 0.403 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 3.956171e-01 | 0.403 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 3.956171e-01 | 0.403 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 3.956171e-01 | 0.403 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 4.005484e-01 | 0.397 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 4.074510e-01 | 0.390 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 4.108675e-01 | 0.386 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 4.108675e-01 | 0.386 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 4.121977e-01 | 0.385 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 4.125306e-01 | 0.385 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.143458e-01 | 0.383 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 4.143458e-01 | 0.383 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 4.143458e-01 | 0.383 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 4.143458e-01 | 0.383 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 4.143458e-01 | 0.383 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 4.145370e-01 | 0.382 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 4.182704e-01 | 0.379 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.206467e-01 | 0.376 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 4.206467e-01 | 0.376 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 4.206467e-01 | 0.376 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 4.206467e-01 | 0.376 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 4.206467e-01 | 0.376 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 4.206467e-01 | 0.376 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 4.215199e-01 | 0.375 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 4.215199e-01 | 0.375 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 4.215199e-01 | 0.375 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 4.244477e-01 | 0.372 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 4.328917e-01 | 0.364 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 4.328917e-01 | 0.364 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.328917e-01 | 0.364 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 4.328917e-01 | 0.364 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.328917e-01 | 0.364 | 0 | 0 |
| RUNX2 regulates genes involved in differentiation of myeloid cells | R-HSA-8941333 | 4.328917e-01 | 0.364 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 4.328917e-01 | 0.364 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 4.328917e-01 | 0.364 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 4.328917e-01 | 0.364 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 4.328917e-01 | 0.364 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 4.353846e-01 | 0.361 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 4.388730e-01 | 0.358 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 4.388730e-01 | 0.358 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 4.388730e-01 | 0.358 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 4.423088e-01 | 0.354 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.423088e-01 | 0.354 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 4.453171e-01 | 0.351 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 4.453171e-01 | 0.351 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 4.453171e-01 | 0.351 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 4.453171e-01 | 0.351 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 4.453171e-01 | 0.351 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.453171e-01 | 0.351 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 4.463560e-01 | 0.350 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 4.463560e-01 | 0.350 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 4.463560e-01 | 0.350 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 4.463560e-01 | 0.350 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 4.463560e-01 | 0.350 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 4.463560e-01 | 0.350 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 4.463560e-01 | 0.350 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 4.463560e-01 | 0.350 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 4.463560e-01 | 0.350 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 4.518156e-01 | 0.345 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 4.621121e-01 | 0.335 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 4.621121e-01 | 0.335 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 4.621121e-01 | 0.335 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 4.621121e-01 | 0.335 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 4.621121e-01 | 0.335 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 4.666477e-01 | 0.331 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.690734e-01 | 0.329 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 4.695587e-01 | 0.328 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 4.695587e-01 | 0.328 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 4.731464e-01 | 0.325 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 4.750171e-01 | 0.323 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 4.773601e-01 | 0.321 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 4.773601e-01 | 0.321 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 4.773601e-01 | 0.321 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 4.773601e-01 | 0.321 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 4.773601e-01 | 0.321 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 4.773601e-01 | 0.321 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 4.773601e-01 | 0.321 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.773601e-01 | 0.321 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 4.831527e-01 | 0.316 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 4.840574e-01 | 0.315 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 4.840574e-01 | 0.315 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.840574e-01 | 0.315 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.840574e-01 | 0.315 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 4.840574e-01 | 0.315 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 4.840574e-01 | 0.315 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.840574e-01 | 0.315 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 4.840574e-01 | 0.315 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 4.840574e-01 | 0.315 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 4.840574e-01 | 0.315 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 4.840574e-01 | 0.315 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 4.840574e-01 | 0.315 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 4.840574e-01 | 0.315 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 4.840574e-01 | 0.315 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 4.845292e-01 | 0.315 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 4.892844e-01 | 0.310 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 4.918914e-01 | 0.308 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 4.918914e-01 | 0.308 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 4.928052e-01 | 0.307 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 4.933109e-01 | 0.307 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 4.996448e-01 | 0.301 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 5.031253e-01 | 0.298 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 5.031253e-01 | 0.298 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 5.043180e-01 | 0.297 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 5.063670e-01 | 0.296 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 5.072792e-01 | 0.295 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 5.072792e-01 | 0.295 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 5.072792e-01 | 0.295 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 5.072792e-01 | 0.295 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 5.166873e-01 | 0.287 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 5.167319e-01 | 0.287 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 5.227502e-01 | 0.282 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 5.281152e-01 | 0.277 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.306095e-01 | 0.275 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.306095e-01 | 0.275 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 5.306095e-01 | 0.275 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.306095e-01 | 0.275 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 5.306095e-01 | 0.275 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 5.306095e-01 | 0.275 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 5.306095e-01 | 0.275 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.306095e-01 | 0.275 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 5.306095e-01 | 0.275 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 5.306095e-01 | 0.275 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 5.306095e-01 | 0.275 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 5.306095e-01 | 0.275 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 5.306095e-01 | 0.275 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 5.306095e-01 | 0.275 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 5.306095e-01 | 0.275 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 5.306095e-01 | 0.275 | 0 | 0 |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors | R-HSA-389397 | 5.306095e-01 | 0.275 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 5.316994e-01 | 0.274 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 5.353636e-01 | 0.271 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 5.360566e-01 | 0.271 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 5.360566e-01 | 0.271 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 5.360566e-01 | 0.271 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 5.386477e-01 | 0.269 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 5.388929e-01 | 0.268 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 5.391484e-01 | 0.268 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 5.391484e-01 | 0.268 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 5.391484e-01 | 0.268 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 5.405291e-01 | 0.267 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 5.419963e-01 | 0.266 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 5.447065e-01 | 0.264 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 5.447065e-01 | 0.264 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 5.447065e-01 | 0.264 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 5.587374e-01 | 0.253 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 5.608363e-01 | 0.251 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 5.611539e-01 | 0.251 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 5.611539e-01 | 0.251 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 5.611539e-01 | 0.251 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 5.611539e-01 | 0.251 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 5.611539e-01 | 0.251 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 5.614420e-01 | 0.251 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 5.636549e-01 | 0.249 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 5.636549e-01 | 0.249 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 5.636549e-01 | 0.249 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 5.636549e-01 | 0.249 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 5.666396e-01 | 0.247 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 5.729639e-01 | 0.242 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.729639e-01 | 0.242 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.729639e-01 | 0.242 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 5.729639e-01 | 0.242 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.729639e-01 | 0.242 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.729639e-01 | 0.242 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 5.729639e-01 | 0.242 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 5.729639e-01 | 0.242 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 5.729639e-01 | 0.242 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 5.729639e-01 | 0.242 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 5.729639e-01 | 0.242 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.729639e-01 | 0.242 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.729639e-01 | 0.242 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 5.729639e-01 | 0.242 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 5.729639e-01 | 0.242 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.729639e-01 | 0.242 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 5.729639e-01 | 0.242 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 5.825095e-01 | 0.235 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 5.825095e-01 | 0.235 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 5.825095e-01 | 0.235 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 5.825095e-01 | 0.235 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 5.900525e-01 | 0.229 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 5.900525e-01 | 0.229 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 5.900525e-01 | 0.229 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 5.900525e-01 | 0.229 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 5.900525e-01 | 0.229 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 5.900525e-01 | 0.229 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 5.938455e-01 | 0.226 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 5.939495e-01 | 0.226 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 6.031924e-01 | 0.220 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 6.065829e-01 | 0.217 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 6.065829e-01 | 0.217 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.114988e-01 | 0.214 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 6.114988e-01 | 0.214 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 6.114988e-01 | 0.214 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.114988e-01 | 0.214 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 6.114988e-01 | 0.214 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 6.114988e-01 | 0.214 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.114988e-01 | 0.214 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 6.114988e-01 | 0.214 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 6.114988e-01 | 0.214 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 6.114988e-01 | 0.214 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 6.147001e-01 | 0.211 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 6.152415e-01 | 0.211 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 6.152415e-01 | 0.211 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 6.152415e-01 | 0.211 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 6.152415e-01 | 0.211 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 6.207235e-01 | 0.207 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 6.231859e-01 | 0.205 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 6.231859e-01 | 0.205 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 6.231859e-01 | 0.205 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 6.231859e-01 | 0.205 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 6.231859e-01 | 0.205 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 6.231859e-01 | 0.205 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 6.253619e-01 | 0.204 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 6.259354e-01 | 0.203 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 6.279338e-01 | 0.202 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 6.307028e-01 | 0.200 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 6.317129e-01 | 0.199 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 6.317129e-01 | 0.199 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 6.317129e-01 | 0.199 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 6.392249e-01 | 0.194 | 0 | 0 |
| PKA activation | R-HSA-163615 | 6.392249e-01 | 0.194 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 6.392249e-01 | 0.194 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 6.392249e-01 | 0.194 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 6.392249e-01 | 0.194 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 6.392249e-01 | 0.194 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 6.400828e-01 | 0.194 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 6.424784e-01 | 0.192 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 6.424784e-01 | 0.192 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 6.424784e-01 | 0.192 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 6.433668e-01 | 0.192 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.465585e-01 | 0.189 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.465585e-01 | 0.189 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.465585e-01 | 0.189 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.465585e-01 | 0.189 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of keratinocytes | R-HSA-8939242 | 6.465585e-01 | 0.189 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 6.465585e-01 | 0.189 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 6.465585e-01 | 0.189 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 6.465585e-01 | 0.189 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.465585e-01 | 0.189 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 6.465585e-01 | 0.189 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 6.465585e-01 | 0.189 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.465585e-01 | 0.189 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 6.482343e-01 | 0.188 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 6.557741e-01 | 0.183 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 6.610630e-01 | 0.180 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 6.610630e-01 | 0.180 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 6.610630e-01 | 0.180 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 6.610630e-01 | 0.180 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 6.620151e-01 | 0.179 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 6.620151e-01 | 0.179 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 6.620151e-01 | 0.179 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.620151e-01 | 0.179 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 6.620151e-01 | 0.179 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 6.620151e-01 | 0.179 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 6.620151e-01 | 0.179 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.630731e-01 | 0.178 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 6.642561e-01 | 0.178 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 6.727478e-01 | 0.172 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 6.784562e-01 | 0.168 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 6.784562e-01 | 0.168 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 6.784562e-01 | 0.168 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.784562e-01 | 0.168 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.784562e-01 | 0.168 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 6.784562e-01 | 0.168 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 6.797726e-01 | 0.168 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 6.797726e-01 | 0.168 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 6.836323e-01 | 0.165 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 6.924270e-01 | 0.160 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 6.947806e-01 | 0.158 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 6.947806e-01 | 0.158 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 6.961024e-01 | 0.157 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 6.961024e-01 | 0.157 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 7.009979e-01 | 0.154 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 7.041024e-01 | 0.152 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 7.074768e-01 | 0.150 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 7.074768e-01 | 0.150 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 7.074768e-01 | 0.150 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 7.074768e-01 | 0.150 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 7.074768e-01 | 0.150 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 7.074768e-01 | 0.150 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 7.074768e-01 | 0.150 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 7.074768e-01 | 0.150 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 7.092789e-01 | 0.149 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 7.110884e-01 | 0.148 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 7.110884e-01 | 0.148 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 7.125629e-01 | 0.147 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 7.125629e-01 | 0.147 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 7.234564e-01 | 0.141 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 7.234564e-01 | 0.141 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 7.283265e-01 | 0.138 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 7.283265e-01 | 0.138 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 7.338798e-01 | 0.134 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.338798e-01 | 0.134 | 0 | 0 |
| Conjugation of benzoate with glycine | R-HSA-177135 | 7.338798e-01 | 0.134 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 7.338798e-01 | 0.134 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 7.338798e-01 | 0.134 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 7.338798e-01 | 0.134 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.338798e-01 | 0.134 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.338798e-01 | 0.134 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 7.417290e-01 | 0.130 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 7.417290e-01 | 0.130 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.417290e-01 | 0.130 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 7.417290e-01 | 0.130 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 7.434031e-01 | 0.129 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 7.434031e-01 | 0.129 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 7.497316e-01 | 0.125 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 7.497316e-01 | 0.125 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 7.558284e-01 | 0.122 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 7.578051e-01 | 0.120 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.579011e-01 | 0.120 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 7.579011e-01 | 0.120 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 7.579011e-01 | 0.120 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 7.579011e-01 | 0.120 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.579011e-01 | 0.120 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 7.579011e-01 | 0.120 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 7.579011e-01 | 0.120 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 7.579011e-01 | 0.120 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.579011e-01 | 0.120 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 7.579011e-01 | 0.120 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.589576e-01 | 0.120 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 7.589576e-01 | 0.120 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.589576e-01 | 0.120 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 7.686549e-01 | 0.114 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 7.715465e-01 | 0.113 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 7.715465e-01 | 0.113 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 7.751818e-01 | 0.111 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.751818e-01 | 0.111 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 7.758620e-01 | 0.110 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 7.781773e-01 | 0.109 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 7.793384e-01 | 0.108 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 7.797554e-01 | 0.108 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 7.797554e-01 | 0.108 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 7.797554e-01 | 0.108 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 7.797554e-01 | 0.108 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 7.797554e-01 | 0.108 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 7.797554e-01 | 0.108 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 7.797554e-01 | 0.108 | 0 | 0 |
| Acetylation | R-HSA-156582 | 7.797554e-01 | 0.108 | 0 | 0 |
| Conjugation of salicylate with glycine | R-HSA-177128 | 7.797554e-01 | 0.108 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 7.797554e-01 | 0.108 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 7.797554e-01 | 0.108 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.797554e-01 | 0.108 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 7.797554e-01 | 0.108 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.797554e-01 | 0.108 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 7.797554e-01 | 0.108 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 7.797554e-01 | 0.108 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 7.797554e-01 | 0.108 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 7.797554e-01 | 0.108 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 7.797554e-01 | 0.108 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 7.797554e-01 | 0.108 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 7.797554e-01 | 0.108 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.797554e-01 | 0.108 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 7.896375e-01 | 0.103 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 7.904425e-01 | 0.102 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 7.904425e-01 | 0.102 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 7.904425e-01 | 0.102 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 7.904425e-01 | 0.102 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.904425e-01 | 0.102 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 7.904425e-01 | 0.102 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 7.904425e-01 | 0.102 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 7.921143e-01 | 0.101 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 7.948498e-01 | 0.100 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 7.967595e-01 | 0.099 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.967595e-01 | 0.099 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 7.971119e-01 | 0.098 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 7.971119e-01 | 0.098 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 7.979788e-01 | 0.098 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 7.996381e-01 | 0.097 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 7.996381e-01 | 0.097 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 7.996381e-01 | 0.097 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 7.996381e-01 | 0.097 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 7.996381e-01 | 0.097 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 8.047814e-01 | 0.094 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 8.153974e-01 | 0.089 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 8.177270e-01 | 0.087 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 8.177270e-01 | 0.087 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.177270e-01 | 0.087 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 8.177270e-01 | 0.087 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.177270e-01 | 0.087 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.177270e-01 | 0.087 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 8.177270e-01 | 0.087 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 8.177270e-01 | 0.087 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 8.177270e-01 | 0.087 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 8.182405e-01 | 0.087 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.182405e-01 | 0.087 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 8.182405e-01 | 0.087 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.182405e-01 | 0.087 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.182405e-01 | 0.087 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 8.202389e-01 | 0.086 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 8.202389e-01 | 0.086 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 8.202389e-01 | 0.086 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 8.202389e-01 | 0.086 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 8.271381e-01 | 0.082 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.308034e-01 | 0.081 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 8.308618e-01 | 0.080 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 8.308618e-01 | 0.080 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 8.341837e-01 | 0.079 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.341837e-01 | 0.079 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 8.341837e-01 | 0.079 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 8.341837e-01 | 0.079 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 8.341837e-01 | 0.079 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 8.341837e-01 | 0.079 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 8.341837e-01 | 0.079 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 8.341837e-01 | 0.079 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 8.341837e-01 | 0.079 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.363834e-01 | 0.078 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 8.381611e-01 | 0.077 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 8.426867e-01 | 0.074 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 8.426867e-01 | 0.074 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 8.491555e-01 | 0.071 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.491555e-01 | 0.071 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 8.491555e-01 | 0.071 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 8.491555e-01 | 0.071 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 8.491555e-01 | 0.071 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 8.491555e-01 | 0.071 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 8.491555e-01 | 0.071 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 8.491555e-01 | 0.071 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 8.491555e-01 | 0.071 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 8.491555e-01 | 0.071 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 8.491555e-01 | 0.071 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 8.491555e-01 | 0.071 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.491555e-01 | 0.071 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 8.491555e-01 | 0.071 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 8.491555e-01 | 0.071 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 8.537562e-01 | 0.069 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 8.595865e-01 | 0.066 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 8.616827e-01 | 0.065 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.627763e-01 | 0.064 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 8.627763e-01 | 0.064 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 8.627763e-01 | 0.064 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 8.627763e-01 | 0.064 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.627763e-01 | 0.064 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 8.627763e-01 | 0.064 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.627763e-01 | 0.064 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.641103e-01 | 0.063 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 8.641103e-01 | 0.063 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.641103e-01 | 0.063 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 8.661297e-01 | 0.062 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 8.662512e-01 | 0.062 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 8.662512e-01 | 0.062 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 8.737877e-01 | 0.059 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 8.751679e-01 | 0.058 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 8.751679e-01 | 0.058 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.751679e-01 | 0.058 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.751679e-01 | 0.058 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 8.751679e-01 | 0.058 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 8.751679e-01 | 0.058 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 8.766227e-01 | 0.057 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 8.766227e-01 | 0.057 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 8.828263e-01 | 0.054 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.835545e-01 | 0.054 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 8.835545e-01 | 0.054 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 8.842420e-01 | 0.053 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 8.842420e-01 | 0.053 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 8.851847e-01 | 0.053 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 8.864412e-01 | 0.052 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 8.864412e-01 | 0.052 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 8.864412e-01 | 0.052 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 8.864412e-01 | 0.052 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.864412e-01 | 0.052 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 8.864412e-01 | 0.052 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 8.864412e-01 | 0.052 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 8.865839e-01 | 0.052 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 8.897380e-01 | 0.051 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 8.901446e-01 | 0.051 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.912625e-01 | 0.050 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 8.912625e-01 | 0.050 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 8.966970e-01 | 0.047 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 8.966970e-01 | 0.047 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 8.966970e-01 | 0.047 | 0 | 0 |
| Conjugation of carboxylic acids | R-HSA-159424 | 8.966970e-01 | 0.047 | 0 | 0 |
| Amino Acid conjugation | R-HSA-156587 | 8.966970e-01 | 0.047 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.966970e-01 | 0.047 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 8.966970e-01 | 0.047 | 0 | 0 |
| Methionine salvage pathway | R-HSA-1237112 | 8.966970e-01 | 0.047 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 8.966970e-01 | 0.047 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 8.984254e-01 | 0.047 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 8.991314e-01 | 0.046 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 8.991314e-01 | 0.046 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 8.991314e-01 | 0.046 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.045272e-01 | 0.044 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.050310e-01 | 0.043 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.060272e-01 | 0.043 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 9.060272e-01 | 0.043 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 9.060272e-01 | 0.043 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 9.060272e-01 | 0.043 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.060272e-01 | 0.043 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.060272e-01 | 0.043 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.064665e-01 | 0.043 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.064665e-01 | 0.043 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.064665e-01 | 0.043 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 9.079923e-01 | 0.042 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 9.079923e-01 | 0.042 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.080948e-01 | 0.042 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.086624e-01 | 0.042 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.133001e-01 | 0.039 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.133001e-01 | 0.039 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 9.133424e-01 | 0.039 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.145152e-01 | 0.039 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 9.145152e-01 | 0.039 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 9.145152e-01 | 0.039 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 9.145152e-01 | 0.039 | 0 | 0 |
| Phenylalanine metabolism | R-HSA-8964208 | 9.145152e-01 | 0.039 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.145152e-01 | 0.039 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 9.145152e-01 | 0.039 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.145152e-01 | 0.039 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.145152e-01 | 0.039 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.166231e-01 | 0.038 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.196629e-01 | 0.036 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.196629e-01 | 0.036 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.206383e-01 | 0.036 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 9.222140e-01 | 0.035 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 9.222369e-01 | 0.035 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 9.222369e-01 | 0.035 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.222369e-01 | 0.035 | 0 | 0 |
| Androgen biosynthesis | R-HSA-193048 | 9.222369e-01 | 0.035 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.222369e-01 | 0.035 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.255842e-01 | 0.034 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.268337e-01 | 0.033 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.270844e-01 | 0.033 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.277646e-01 | 0.033 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.292616e-01 | 0.032 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.292616e-01 | 0.032 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.292616e-01 | 0.032 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 9.292616e-01 | 0.032 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.305337e-01 | 0.031 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.356521e-01 | 0.029 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 9.356521e-01 | 0.029 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.356521e-01 | 0.029 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.356521e-01 | 0.029 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.356521e-01 | 0.029 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.361381e-01 | 0.029 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 9.409699e-01 | 0.026 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.409699e-01 | 0.026 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.414656e-01 | 0.026 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 9.414656e-01 | 0.026 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 9.414656e-01 | 0.026 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.414656e-01 | 0.026 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.414656e-01 | 0.026 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.414656e-01 | 0.026 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.444779e-01 | 0.025 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.444779e-01 | 0.025 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.452456e-01 | 0.024 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.453891e-01 | 0.024 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.453891e-01 | 0.024 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.453891e-01 | 0.024 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.467542e-01 | 0.024 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 9.467542e-01 | 0.024 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 9.467542e-01 | 0.024 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.483640e-01 | 0.023 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.494921e-01 | 0.023 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 9.515653e-01 | 0.022 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.515653e-01 | 0.022 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.515653e-01 | 0.022 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.515653e-01 | 0.022 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 9.515653e-01 | 0.022 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.516498e-01 | 0.022 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.541845e-01 | 0.020 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.551718e-01 | 0.020 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.559419e-01 | 0.020 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 9.559419e-01 | 0.020 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.568321e-01 | 0.019 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.599233e-01 | 0.018 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.599233e-01 | 0.018 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.599233e-01 | 0.018 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 9.608022e-01 | 0.017 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.615134e-01 | 0.017 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.635451e-01 | 0.016 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.635451e-01 | 0.016 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.635674e-01 | 0.016 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.668398e-01 | 0.015 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.698369e-01 | 0.013 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.709772e-01 | 0.013 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 9.750434e-01 | 0.011 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.750434e-01 | 0.011 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.772994e-01 | 0.010 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.778828e-01 | 0.010 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 9.793517e-01 | 0.009 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.812185e-01 | 0.008 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.812185e-01 | 0.008 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.821092e-01 | 0.008 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.822307e-01 | 0.008 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.823068e-01 | 0.008 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 9.843194e-01 | 0.007 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.844613e-01 | 0.007 | 0 | 0 |
| Phenylalanine and tyrosine metabolism | R-HSA-8963691 | 9.844613e-01 | 0.007 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.844613e-01 | 0.007 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.858664e-01 | 0.006 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.858664e-01 | 0.006 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.859904e-01 | 0.006 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.867785e-01 | 0.006 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.876588e-01 | 0.005 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.877193e-01 | 0.005 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.881085e-01 | 0.005 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.881085e-01 | 0.005 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.883071e-01 | 0.005 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.883071e-01 | 0.005 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.883071e-01 | 0.005 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 9.886015e-01 | 0.005 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.890470e-01 | 0.005 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.893646e-01 | 0.005 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.896856e-01 | 0.005 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.907089e-01 | 0.004 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.907123e-01 | 0.004 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.914494e-01 | 0.004 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.919974e-01 | 0.003 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.919974e-01 | 0.003 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.919974e-01 | 0.003 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.924276e-01 | 0.003 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.925710e-01 | 0.003 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.927214e-01 | 0.003 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.927561e-01 | 0.003 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.935114e-01 | 0.003 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.938767e-01 | 0.003 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.942405e-01 | 0.003 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.945236e-01 | 0.002 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.945236e-01 | 0.002 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.945788e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.950191e-01 | 0.002 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.952266e-01 | 0.002 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.952266e-01 | 0.002 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.958798e-01 | 0.002 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.962527e-01 | 0.002 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.965890e-01 | 0.001 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.971809e-01 | 0.001 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.975319e-01 | 0.001 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.975319e-01 | 0.001 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.975319e-01 | 0.001 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.976682e-01 | 0.001 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.978301e-01 | 0.001 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.978904e-01 | 0.001 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.980713e-01 | 0.001 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.985492e-01 | 0.001 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.987689e-01 | 0.001 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.988001e-01 | 0.001 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.988633e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.989088e-01 | 0.000 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.991015e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.991263e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.991563e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.991793e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.991793e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.991793e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.992536e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.993054e-01 | 0.000 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.994387e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.994665e-01 | 0.000 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.995779e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.995811e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.995852e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.996131e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.996252e-01 | 0.000 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.996825e-01 | 0.000 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.997098e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.997113e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.997375e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.997375e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.997829e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.998368e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999097e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999608e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999676e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999749e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999781e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999799e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999830e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999856e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999897e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999904e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999919e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999931e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999977e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999979e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999991e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999996e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999996e-01 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 9.999996e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999997e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999998e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999999e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
