MLK1
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0A2R8Y4L2 | S95 | Sugiyama | HNRNPA1L3 HNRNPA1P48 | RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED |
| A5A3E0 | S1065 | Sugiyama | POTEF A26C1B | ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________ |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | T949 | Sugiyama | POTEF A26C1B | TVAsSSSLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| A6NKT7 | S919 | Sugiyama | RGPD3 RGP3 | tKGSSNTEFKSTKEGFSIPVsADGFKFGIsEPGNQEKKSEK |
| A6NMY6 | S134 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD |
| A6NMY6 | S22 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | stVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNI |
| A6NMY6 | T19 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | __MstVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDA |
| A6NMY6 | Y24 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | VHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEt |
| O00151 | S31 | Sugiyama | PDLIM1 CLIM1 CLP36 | PGPWGFRLVGGKDFEQPLAIsRVtPGSKAALANLCIGDVIT |
| O00161 | S23 | Sugiyama | SNAP23 | NLssEEIQQRAHQITDEsLEstRRILGLAIEsQDAGIKtIt |
| O00233 | S46 | Sugiyama | PSMD9 | LMRRKEEIEAQIKANyDVLEsQKGIGMNEPLVDCEGyPRSD |
| O00429 | T586 | Sugiyama | DNM1L DLP1 DRP1 | ETKNVAsGGGGVGDGVQEPTtGNWRGMLKtSKAEELLAEEK |
| O00571 | S71 | Sugiyama | DDX3X DBX DDX3 | GFyDKDSSGWsssKDKDAyssFGsRsDsRGKssFFsDRGsG |
| O14715 | S918 | Sugiyama | RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3 | tKGSSNTEFKSTKEGFSIPVsADGFKFGIsEPGNQEKKREK |
| O14737 | S51 | Sugiyama | PDCD5 TFAR19 | EAKHREAEMRNsILAQVLDQsARARLsNLALVKPEKTKAVE |
| O14950 | T160 | Sugiyama | MYL12B MRLC2 MYLC2B | DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________ |
| O15127 | T109 | Sugiyama | SCAMP2 | QEELDRKAAELERKERELQNtVANLHVRQNNWPPLPSWCPV |
| O15523 | S71 | Sugiyama | DDX3Y DBY | GFHDKDSSGWSCSKDKDAyssFGsRDSRGKPGYFSERGSGS |
| O43175 | T89 | Sugiyama | PHGDH PGDH3 | KLQVVGRAGtGVDNVDLEAAtRKGILVMNTPNGNSLSAAEL |
| O43242 | S63 | Sugiyama | PSMD3 | tGGGstGEADGKtAAAAAEHsQRELDtVtLEDIKEHVKQLE |
| O43242 | T69 | Sugiyama | PSMD3 | GEADGKtAAAAAEHsQRELDtVtLEDIKEHVKQLEKAVSGK |
| O43399 | S145 | Sugiyama | TPD52L2 | LyKKTQETLsQAGQKtsAALstVGsAIsRKLGDMRNsAtFK |
| O43399 | S152 | Sugiyama | TPD52L2 | TLsQAGQKtsAALstVGsAIsRKLGDMRNsAtFKsFEDRVG |
| O43707 | S642 | Sugiyama | ACTN4 | KWEKVQQLVPKRDHALLEEQsKQQSNEHLRRQFAsQANVVG |
| O43852 | S69 | Sugiyama | CALU | HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt |
| O43852 | T196 | Sugiyama | CALU | FtAFLHPEEyDyMKDIVVQEtMEDIDKNADGFIDLEEyIGD |
| O43852 | T89 | Sugiyama | CALU | sKERLGKIVSKIDGDKDGFVtVDELKDWIKFAQKRWIyEDV |
| O60361 | S107 | Sugiyama | NME2P1 | GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDY |
| O60361 | S110 | Sugiyama | NME2P1 | RGDFCIQVGRNIIHGsDsVKsAEKEISLRFKPEELVDYKSC |
| O60610 | S793 | Sugiyama | DIAPH1 DIAP1 | YKPEVQLRRPNWSKLVAEDLsQDCFWtKVKEDRFENNELFA |
| O60610 | T799 | Sugiyama | DIAPH1 DIAP1 | LRRPNWSKLVAEDLsQDCFWtKVKEDRFENNELFAKLTLTF |
| O60664 | S175 | Sugiyama | PLIN3 M6PRBP1 TIP47 | RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK |
| O60664 | S225 | Sugiyama | PLIN3 M6PRBP1 TIP47 | PLTDAELARIAtsLDGFDVAsVQQQRQEQSyFVRLGsLSER |
| O60841 | S196 | Sugiyama | EIF5B IF2 KIAA0741 | ERsRINssGEsGDEsDEFLQsRKGQKKNQKNKPGPNIEsGN |
| O60841 | S222 | Sugiyama | EIF5B IF2 KIAA0741 | KNQKNKPGPNIEsGNEDDDAsFKIKTVAQKKAEKKERERKK |
| O60925 | S78 | Sugiyama | PFDN1 PFD1 | TNMYEGVGRMFILQSKEAIHsQLLEKQKIAEEKIKELEQKK |
| O75794 | S303 | Sugiyama | CDC123 C10orf7 D123 | DSPAFRCTNSEVtVQPsPyLsyRLPKDFVDLsTGEDAHKLI |
| O75794 | T295 | Sugiyama | CDC123 C10orf7 D123 | SEVDAQEQDSPAFRCTNSEVtVQPsPyLsyRLPKDFVDLsT |
| O75828 | S69 | Sugiyama | CBR3 SDR21C2 | QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLNVLVN |
| O94804 | T896 | Sugiyama | STK10 LOK | NMSELQQLQNEKCHLLVEHEtQKLKALDESHNQNLKEWRDK |
| O95373 | T968 | Sugiyama | IPO7 RANBP7 | IIDDEDNPVDEYQIFKAIFQtIQNRNPVWyQALTHGLNEEQ |
| O95433 | T20 | Sugiyama | AHSA1 C14orf3 HSPC322 | _MAKWGEGDPRWIVEERADAtNVNNWHWtERDASNWSTDKL |
| O95678 | S162 | Sugiyama | KRT75 K6HF KB18 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| O95747 | S495 | Sugiyama | OXSR1 KIAA1101 OSR1 | DGRDLVIVAANLQKIVEEPQsNRsVTFKLASGVEGsDIPDD |
| O95747 | S498 | Sugiyama | OXSR1 KIAA1101 OSR1 | DLVIVAANLQKIVEEPQsNRsVTFKLASGVEGsDIPDDGKL |
| O95757 | S599 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND |
| O95816 | S31 | Sugiyama | BAG2 | NEGRFCRsssMADRsSRLLEsLDQLELRVEALREAATAVEQ |
| O95831 | T188 | Sugiyama | AIFM1 AIF PDCD8 | LPYMRPPLSKELWFSDDPNVtKtLRFKQWNGKERSIYFQPP |
| O95831 | T190 | Sugiyama | AIFM1 AIF PDCD8 | YMRPPLSKELWFSDDPNVtKtLRFKQWNGKERSIYFQPPSF |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P00338 | S319 | Sugiyama | LDHA PIG19 | GISDLVKVTLtsEEEARLKKsADtLWGIQKELQF_______ |
| P00558 | S115 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | FLKDCVGPEVEKACANPAAGsVILLENLRFHVEEEGKGKDA |
| P00558 | S174 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | S390 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | IIGGGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPG |
| P00558 | S393 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | GGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDA |
| P00558 | S399 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__ |
| P02538 | S176 | Sugiyama | KRT6A K6A KRT6D | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT |
| P02786 | S159 | Sugiyama | TFRC | DFTGtIKLLNENsyVPREAGsQKDENLALyVENQFREFKLS |
| P04040 | T43 | Sugiyama | CAT | KADVLttGAGNPVGDKLNVItVGPRGPLLVQDVVFTDEMAH |
| P04040 | T441 | Sugiyama | CAT | HSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEEQRKRLCE |
| P04075 | S132 | Sugiyama | ALDOA ALDA | GVVPLAGtNGEtttQGLDGLsERCAQYKKDGADFAKWRCVL |
| P04075 | S17 | Sugiyama | ALDOA ALDA | ____MPyQyPALtPEQKKELsDIAHRIVAPGKGILAADEst |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S356 | Sugiyama | ALDOA ALDA | sLACQGKytPsGQAGAAAsEsLFVsNHAy____________ |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S360 | Sugiyama | ALDOA ALDA | QGKytPsGQAGAAAsEsLFVsNHAy________________ |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T123 | Sugiyama | ALDOA ALDA | GVVGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGA |
| P04075 | T125 | Sugiyama | ALDOA ALDA | VGIKVDKGVVPLAGtNGEtttQGLDGLsERCAQYKKDGADF |
| P04083 | S143 | Sugiyama | ANXA1 ANX1 LPC1 | LRAAMKGLGtDEDtLIEILAsRtNKEIRDINRVYREELKRD |
| P04083 | S173 | Sugiyama | ANXA1 ANX1 LPC1 | NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG |
| P04083 | S201 | Sugiyama | ANXA1 ANX1 LPC1 | LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF |
| P04083 | T169 | Sugiyama | ANXA1 ANX1 LPC1 | IRDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRs |
| P04083 | T172 | Sugiyama | ANXA1 ANX1 LPC1 | INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF |
| P04083 | T223 | Sugiyama | ANXA1 ANX1 LPC1 | ARALyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKY |
| P04083 | T226 | Sugiyama | ANXA1 ANX1 LPC1 | LyEAGERRKGtDVNVFNtILttRSyPQLRRVFQKYTKYSKH |
| P04259 | S176 | Sugiyama | KRT6B K6B KRTL1 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | S98 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | QERDPsKIKWGDAGAEyVVEstGVFttMEKAGAHLQGGAKR |
| P04406 | T103 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sKIKWGDAGAEyVVEstGVFttMEKAGAHLQGGAKRVIIsA |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04792 | S176 | Sugiyama | HSPB1 HSP27 HSP28 | sLsPEGtLTVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEA |
| P04792 | S26 | Sugiyama | HSPB1 HSP27 HSP28 | VPFsLLRGPsWDPFRDWyPHsRLFDQAFGLPRLPEEWSQWL |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P04792 | T184 | Sugiyama | HSPB1 HSP27 HSP28 | TVEAPMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAA |
| P05187 | T185 | Sugiyama | ALPP PLAP | VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC |
| P05198 | S219 | Sugiyama | EIF2S1 EIF2A | CYGYEGIDAVKEALRAGLNCsTENMPIKINLIAPPRYVMTT |
| P05386 | S101 | Sugiyama | RPLP1 RRP1 | APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______ |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S102 | Sugiyama | RPLP2 D11S2243E RPP2 | PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S19 | Sugiyama | RPLP2 D11S2243E RPP2 | __MRyVAsyLLAALGGNssPsAKDIKKILDsVGIEADDDRL |
| P05387 | S29 | Sugiyama | RPLP2 D11S2243E RPP2 | LAALGGNssPsAKDIKKILDsVGIEADDDRLNKVIsELNGK |
| P05388 | S307 | Sugiyama | RPLP0 | AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________ |
| P05455 | S112 | Sugiyama | SSB | sPsKPLPEVTDEyKNDVKNRsVYIKGFPtDAtLDDIKEWLE |
| P05455 | S325 | Sugiyama | SSB | VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA |
| P05783 | T404 | Sugiyama | KRT18 CYK18 PIG46 | LEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVVsETND |
| P05787 | S104 | Sugiyama | KRT8 CYK8 | IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS |
| P05787 | S291 | Sugiyama | KRT8 CYK8 | ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN |
| P05787 | S410 | Sugiyama | KRT8 CYK8 | TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL |
| P06733 | S14 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | _______MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAA |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S291 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA |
| P06733 | S349 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV |
| P06733 | S353 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | S40 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGK |
| P06733 | T19 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA |
| P06733 | T205 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GAEVyHNLKNVIKEKyGKDAtNVGDEGGFAPNILENKEGLE |
| P06733 | T26 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | T55 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP |
| P06744 | S247 | Sugiyama | GPI | EWFLQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFW |
| P06744 | S359 | Sugiyama | GPI | LPYDQYLHRFAAyFQQGDMEsNGKYITKSGtRVDHQTGPIV |
| P06744 | T250 | Sugiyama | GPI | LQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFWDWV |
| P06744 | T251 | Sugiyama | GPI | QAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFWDWVG |
| P06748 | S137 | Sugiyama | NPM1 NPM | VAVEEDAEsEDEEEEDVKLLsIsGKRsAPGGGsKVPQKKVK |
| P06748 | S43 | Sugiyama | NPM1 NPM | LKADKDyHFKVDNDENEHQLsLRTVsLGAGAKDELHIVEAE |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | T18 | Sugiyama | LDHB | ___MATLKEKLIAPVAEEEAtVPNNKITVVGVGQVGMACAI |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07205 | S390 | Sugiyama | PGK2 PGKB | VIGGGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPG |
| P07205 | S393 | Sugiyama | PGK2 PGKB | GGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEA |
| P07205 | S399 | Sugiyama | PGK2 PGKB | CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__ |
| P07237 | S331 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | ECPAVRLITLEEEMTKyKPEsEELtAERItEFCHRFLEGKI |
| P07237 | S449 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | ANEVEAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKF |
| P07237 | T453 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | EAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESG |
| P07237 | Y457 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | VHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESGGQDG |
| P07355 | S134 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | LKAsMKGLGtDEDsLIEIICsRtNQELQEINRVyKEMYKtD |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07355 | S22 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | stVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNI |
| P07355 | T19 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | __MstVHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDA |
| P07355 | Y24 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | VHEILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEt |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | S75 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| P07437 | T107 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC |
| P07437 | T72 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | NEAtGGKyVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| P07437 | Y106 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAES |
| P07814 | S1473 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | CEDWIKKtTARDQDLEPGAPsMGAKSLCIPFKPLCELQPGA |
| P07814 | S335 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt |
| P07814 | T1105 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | SALEKEKTHVADFAPEVAWVtRSGKTELAEPIAIRPTsEtV |
| P07814 | T1222 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | AIPVVKGRKTEKEKFAGGDYtTTIEAFISASGRAIQGGTSH |
| P07858 | T218 | Sugiyama | CTSB CPSB | CTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNSEKD |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S399 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK |
| P07900 | S453 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | NyKKFyEQFSKNIKLGIHEDsQNRKKLsELLRyytsAsGDE |
| P07900 | S468 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | GIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKENQ |
| P07900 | S476 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | RKKLsELLRyytsAsGDEMVsLKDYCTRMKENQKHIyyItG |
| P07900 | S50 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S52 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S543 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | EPIDEyCVQQLKEFEGKtLVsVTKEGLELPEDEEEKKKQEE |
| P07900 | S623 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | tyGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsII |
| P07900 | S641 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD |
| P07900 | S72 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | ssDALDKIRyEsLtDPsKLDsGKELHINLIPNKQDRtLtIV |
| P07900 | T171 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | ITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILHLK |
| P07900 | T195 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DTGEPMGRGTKVILHLKEDQtEyLEERRIKEIVKKHSQFIG |
| P07900 | T645 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL |
| P08133 | T48 | Sugiyama | ANXA6 ANX6 | ALytAMKGFGsDKEAILDIItSRSNRQRQEVCQSYKSLYGK |
| P08195 | S253 | Sugiyama | SLC3A2 MDU1 | FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA |
| P08195 | S286 | Sugiyama | SLC3A2 MDU1 | KNQKDDVAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVIL |
| P08195 | S292 | Sugiyama | SLC3A2 MDU1 | VAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVILDLTPNY |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | T275 | Sugiyama | SLC3A2 MDU1 | KVKGLVLGPIHKNQKDDVAQtDLLQIDPNFGsKEDFDsLLQ |
| P08195 | T401 | Sugiyama | SLC3A2 MDU1 | NSSDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQ |
| P08195 | T411 | Sugiyama | SLC3A2 MDU1 | LLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGNRWC |
| P08195 | T415 | Sugiyama | SLC3A2 MDU1 | NKDLLLtssyLsDsGstGEHtKSLVTQYLNATGNRWCSWSL |
| P08195 | T599 | Sugiyama | SLC3A2 MDU1 | QASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEPH |
| P08238 | S391 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK |
| P08238 | S445 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NyKKFyEAFSKNLKLGIHEDstNRRRLsELLRyHtsQsGDE |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S468 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG |
| P08238 | S470 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | S535 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| P08238 | S615 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | tyGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIV |
| P08238 | S67 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AsDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERtLtLV |
| P08238 | T166 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | ITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILHLK |
| P08238 | T190 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG |
| P08238 | T459 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEt |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | T537 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK |
| P08238 | Y457 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK |
| P08729 | S104 | Sugiyama | KRT7 SCL | LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT |
| P08758 | T196 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | AQALFQAGELKWGTDEEKFItIFGtRSVSHLRKVFDKYMTI |
| P08758 | T200 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | FQAGELKWGTDEEKFItIFGtRSVSHLRKVFDKYMTISGFQ |
| P08865 | S75 | Sugiyama | RPSA LAMBR LAMR1 | WEKLLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtG |
| P08865 | S78 | Sugiyama | RPSA LAMBR LAMR1 | LLLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtP |
| P08865 | S79 | Sugiyama | RPSA LAMBR LAMR1 | LLAARAIVAIENPADVsVIssRNtGQRAVLKFAAAtGAtPI |
| P09104 | S37 | Sugiyama | ENO2 | NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY |
| P09104 | S40 | Sugiyama | ENO2 | VEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGK |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P09382 | T58 | Sugiyama | LGALS1 | DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF |
| P09651 | S365 | Sugiyama | HNRNPA1 HNRPA1 | GQyFAKPRNQGGyGGssssssyGsGRRF_____________ |
| P09651 | S368 | Sugiyama | HNRNPA1 HNRPA1 | FAKPRNQGGyGGssssssyGsGRRF________________ |
| P09651 | S95 | Sugiyama | HNRNPA1 HNRPA1 | RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| P09923 | T182 | Sugiyama | ALPI | VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC |
| P09960 | S486 | Sugiyama | LTA4H LTA4 | TNACIALSQRWITAKEDDLNsFNAtDLKDLsSHQLNEFLAQ |
| P09972 | S132 | Sugiyama | ALDOC ALDC | GVVPLAGtDGEtttQGLDGLsERCAQYKKDGADFAKWRCVL |
| P09972 | T119 | Sugiyama | ALDOC ALDC | QDKGIVVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYK |
| P09972 | T123 | Sugiyama | ALDOC ALDC | IVVGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGA |
| P09972 | T125 | Sugiyama | ALDOC ALDC | VGIKVDKGVVPLAGtDGEtttQGLDGLsERCAQYKKDGADF |
| P0CG38 | S1065 | Sugiyama | POTEI | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1028 | Sugiyama | POTEJ | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | S54 | Sugiyama | TUBA3C TUBA2 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P0DPH7 | T334 | Sugiyama | TUBA3C TUBA2 | ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| P0DPH7 | T337 | Sugiyama | TUBA3C TUBA2 | MLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy |
| P10412 | S55 | Sugiyama | H1-4 H1F4 HIST1H1E | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P10809 | S488 | Sugiyama | HSPD1 HSP60 | IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG |
| P10809 | T117 | Sugiyama | HSPD1 HSP60 | LVQDVANNtNEEAGDGtttAtVLARSIAKEGFEKISKGANP |
| P10809 | T231 | Sugiyama | HSPD1 HSP60 | LEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLsEKKI |
| P10809 | T428 | Sugiyama | HSPD1 HSP60 | GtsDVEVNEKKDRVtDALNAtRAAVEEGIVLGGGCALLRCI |
| P11142 | S329 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | LFRGtLDPVEKALRDAKLDKsQIHDIVLVGGstRIPKIQKL |
| P11142 | S340 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN |
| P11142 | S381 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KsINPDEAVAyGAAVQAAILsGDKSENVQDLLLLDVTPLSL |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | S85 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV |
| P11142 | T163 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11142 | T37 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P11142 | T38 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P11142 | T425 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | TAGGVMTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEG |
| P11142 | T427 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | GGVMTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGER |
| P11142 | T430 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | MTVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMT |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11586 | S323 | Sugiyama | MTHFD1 MTHFC MTHFD | WMIQYNNLNLKTPVPsDIDIsRSCKPKPIGKLAREIGLLSE |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P12035 | S211 | Sugiyama | KRT3 | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN |
| P12268 | S505 | Sugiyama | IMPDH2 IMPD2 | SGELKFEKRtssAQVEGGVHsLHsyEKRLF___________ |
| P12268 | S508 | Sugiyama | IMPDH2 IMPD2 | LKFEKRtssAQVEGGVHsLHsyEKRLF______________ |
| P12268 | Y509 | Sugiyama | IMPDH2 IMPD2 | KFEKRtssAQVEGGVHsLHsyEKRLF_______________ |
| P12277 | S129 | Sugiyama | CKB CKBB | DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG |
| P12277 | S163 | Sugiyama | CKB CKBB | PPHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAE |
| P12429 | S21 | Sugiyama | ANXA3 ANX3 | MASIWVGHRGTVRDyPDFsPsVDAEAIQKAIRGIGTDEKML |
| P13489 | S178 | Sugiyama | RNH1 PRI RNH | SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP |
| P13489 | T176 | Sugiyama | RNH1 PRI RNH | AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S587 | Sugiyama | EEF2 EF2 | CIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKAR |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | T5 | Sugiyama | EEF2 EF2 | ________________MVNFtVDQIRAIMDKKANIRNMsVI |
| P13647 | S181 | Sugiyama | KRT5 | IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P13667 | S126 | Sugiyama | PDIA4 ERP70 ERP72 | NILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILKKG |
| P13667 | S379 | Sugiyama | PDIA4 ERP70 ERP72 | QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH |
| P13929 | S37 | Sugiyama | ENO3 | NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY |
| P13929 | S40 | Sugiyama | ENO3 | VEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGK |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P13987 | T76 | Sugiyama | CD59 MIC11 MIN1 MIN2 MIN3 MSK21 | AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF |
| P14209 | S168 | Sugiyama | CD99 MIC2 MIC2X MIC2Y | YQKKKLCFKENAEQGEVDMEsHRNANAEPAVQRtLLEK___ |
| P14314 | T134 | Sugiyama | PRKCSH G19P1 | NtCKEKGRKEREsLQQMAEVtREGFRLKKILIEDWKKAREE |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S205 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD |
| P14618 | S55 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | IDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMNVARLN |
| P14618 | S77 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sVEtLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEs |
| P14618 | S97 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTKGP |
| P14618 | T195 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | yVDDGLISLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAA |
| P14618 | T41 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | AMADTFLEHMCRLDIDsPPItARNtGIICtIGPAsRsVEtL |
| P14618 | T50 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN |
| P14618 | T80 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | tLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAs |
| P14618 | T87 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP |
| P14618 | T95 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | NFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRPVAVALDTK |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | S501 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | NDTFWKEFGTNIKLGVIEDHsNRtRLAKLLRFQssHHPtDI |
| P14625 | S515 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ |
| P14625 | S64 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR |
| P14625 | S650 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | KIEKAVVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtG |
| P14625 | S655 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | VVSQRLTESPCALVAsQyGWsGNMERIMKAQAYQtGKDIst |
| P14625 | S674 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | WsGNMERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLI |
| P14625 | S680 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | RIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDMLRR |
| P14625 | T519 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | DHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIy |
| P14625 | Y678 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MERIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDML |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P15153 | T161 | Sugiyama | RAC2 | QGLALAKEIDSVKyLECsALtQRGLKtVFDEAIRAVLCPQP |
| P15259 | S189 | Sugiyama | PGAM2 PGAMM | EEIVPQIKAGKRVLIAAHGNsLRGIVKHLEGMSDQAIMELN |
| P15311 | S249 | Sugiyama | EZR VIL2 | EKDDKLtPKIGFPWSEIRNIsFNDKKFVIKPIDKKAPDFVF |
| P15311 | S539 | Sugiyama | EZR VIL2 | TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR |
| P15311 | T533 | Sugiyama | EZR VIL2 | NEEKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDII |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15531 | S125 | Sugiyama | NME1 NDPKA NM23 | RGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDyTsC |
| P15880 | T285 | Sugiyama | RPS2 RPS4 | PyQEFtDHLVKtHtRVsVQRtQAPAVATt____________ |
| P16152 | S69 | Sugiyama | CBR1 CBR CRN SDR21C1 | QLQAEGLsPRFHQLDIDDLQsIRALRDFLRKEYGGLDVLVN |
| P16402 | S56 | Sugiyama | H1-3 H1F3 HIST1H1D | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P16403 | S55 | Sugiyama | H1-2 H1F2 HIST1H1C | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P16949 | S94 | Sugiyama | STMN1 C1orf215 LAP18 OP18 | EKREHEKEVLQKAIEENNNFsKMAEEKLTHKMEANKENREA |
| P17066 | T228 | Sugiyama | HSPA6 HSP70B' | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P17987 | S19 | Sugiyama | TCP1 CCT1 CCTA | __MEGPLsVFGDRSTGEtIRsQNVMAAAsIANIVKssLGPV |
| P17987 | S27 | Sugiyama | TCP1 CCT1 CCTA | VFGDRSTGEtIRsQNVMAAAsIANIVKssLGPVGLDKMLVD |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P17987 | T16 | Sugiyama | TCP1 CCT1 CCTA | _____MEGPLsVFGDRSTGEtIRsQNVMAAAsIANIVKssL |
| P18124 | T17 | Sugiyama | RPL7 | ____MEGVEEKKKEVPAVPEtLKKKRRNFAELKIKRLRKKF |
| P18621 | S14 | Sugiyama | RPL17 | _______MVRysLDPENPtKsCKSRGSNLRVHFKNtRETAQ |
| P18621 | T12 | Sugiyama | RPL17 | _________MVRysLDPENPtKsCKSRGSNLRVHFKNtRET |
| P18621 | T79 | Sugiyama | RPL17 | PFRRYNGGVGRCAQAKQWGWtQGRWPKKSAEFLLHMLKNAE |
| P18669 | S152 | Sugiyama | PGAM1 PGAMA CDABP0006 | FysNIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIV |
| P18669 | S155 | Sugiyama | PGAM1 PGAMA CDABP0006 | NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI |
| P18669 | S189 | Sugiyama | PGAM1 PGAMA CDABP0006 | EEIVPQIKEGKRVLIAAHGNsLRGIVKHLEGLSEEAIMELN |
| P18669 | T146 | Sugiyama | PGAM1 PGAMA CDABP0006 | MEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIARALPF |
| P18669 | T159 | Sugiyama | PGAM1 PGAMA CDABP0006 | DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK |
| P18669 | Y142 | Sugiyama | PGAM1 PGAMA CDABP0006 | PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR |
| P19105 | T159 | Sugiyama | MYL12A MLCB MRLC3 RLC | DELyREAPIDKKGNFNyIEFtRILKHGAKDKDD________ |
| P19338 | S328 | Sugiyama | NCL | NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P20042 | S160 | Sugiyama | EIF2S2 EIF2B | LEKDEALEDEDNKKDDGIsFsNQtGPAWAGSERDytyEELL |
| P20042 | S67 | Sugiyama | EIF2S2 EIF2B | EPtEDKDLEADEEDTRKKDAsDDLDDLNFFNQKKKKKKTKK |
| P20290 | S126 | Sugiyama | BTF3 NACB OK/SW-cl.8 | VNMFTNQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEM |
| P20290 | T133 | Sugiyama | BTF3 NACB OK/SW-cl.8 | GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ |
| P20290 | T135 | Sugiyama | BTF3 NACB OK/SW-cl.8 | VIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLG |
| P20290 | T140 | Sugiyama | BTF3 NACB OK/SW-cl.8 | NPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLGADsLt |
| P20618 | S151 | Sugiyama | PSMB1 PSC5 | PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA |
| P20618 | S162 | Sugiyama | PSMB1 PSC5 | DEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLLDNQVG |
| P21333 | S2558 | Sugiyama | FLNA FLN FLN1 | LtKATCAPQHGAPGPGPADAsKVVAKGLGLSKAYVGQKssF |
| P22314 | S56 | Sugiyama | UBA1 A1S9T UBE1 | VPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSVL |
| P22392 | S122 | Sugiyama | NME2 NM23B | GtIRGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDy |
| P22392 | S125 | Sugiyama | NME2 NM23B | RGDFCIQVGRNIIHGsDsVKsAEKEISLWFKPEELVDyKSC |
| P23246 | S283 | Sugiyama | SFPQ PSF | GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN |
| P23381 | S357 | Sugiyama | WARS1 IFI53 WARS WRS | STFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAF |
| P23381 | T362 | Sugiyama | WARS1 IFI53 WARS WRS | ALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAFsGGRD |
| P23526 | S183 | Sugiyama | AHCY SAHH | NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI |
| P23526 | T157 | Sugiyama | AHCY SAHH | NLIHTKYPQLLPGIRGIsEEtTTGVHNLyKMMANGILKVPA |
| P23528 | S156 | Sugiyama | CFL1 CFL | QANCyEEVKDRCTLAEKLGGsAVIsLEGKPL__________ |
| P23528 | S160 | Sugiyama | CFL1 CFL | yEEVKDRCTLAEKLGGsAVIsLEGKPL______________ |
| P23528 | T63 | Sugiyama | CFL1 CFL | DKKNIILEEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyA |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P24752 | S218 | Sugiyama | ACAT1 ACAT MAT | ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV |
| P24752 | T220 | Sugiyama | ACAT1 ACAT MAT | TAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVtV |
| P24752 | T239 | Sugiyama | ACAT1 ACAT MAT | ytRSKAAWEAGKFGNEVIPVtVtVKGQPDVVVKEDEEyKRV |
| P24752 | T241 | Sugiyama | ACAT1 ACAT MAT | RSKAAWEAGKFGNEVIPVtVtVKGQPDVVVKEDEEyKRVDF |
| P25325 | S218 | Sugiyama | MPST TST2 | DGIEPGHIPGtVNIPFtDFLsQEGLEKsPEEIRHLFQEKKV |
| P25325 | T208 | Sugiyama | MPST TST2 | RFRGTEPEPRDGIEPGHIPGtVNIPFtDFLsQEGLEKsPEE |
| P25325 | T214 | Sugiyama | MPST TST2 | PEPRDGIEPGHIPGtVNIPFtDFLsQEGLEKsPEEIRHLFQ |
| P25705 | S53 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | ARNFHASNTHLQKtGtAEMssILEERILGADtsVDLEETGR |
| P25705 | S65 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | KtGtAEMssILEERILGADtsVDLEETGRVLsIGDGIARVH |
| P25786 | T11 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | __________MFRNQyDNDVtVWsPQGRIHQIEYAMEAVKQ |
| P25786 | T206 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | ELVKHGLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDD |
| P25786 | T207 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | LVKHGLRALRETLPAEQDLttKNVsIGIVGKDLEFTIyDDD |
| P26038 | S144 | Sugiyama | MSN | LLASyAVQSKYGDFNKEVHKsGYLAGDKLLPQRVLEQHKLN |
| P26038 | S249 | Sugiyama | MSN | EQNDRLTPKIGFPWSEIRNIsFNDKKFVIKPIDKKAPDFVF |
| P26038 | S536 | Sugiyama | MSN | ERVQKHLKALtsELANARDEsKKTANDMIHAENMRLGRDKY |
| P26038 | S576 | Sugiyama | MSN | YKtLRQIRQGNTKQRIDEFEsM___________________ |
| P26232 | S667 | Sugiyama | CTNNA2 CAPR | YDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEEKAKIAEQV |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | T148 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PRKPSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARV |
| P26373 | T151 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PSAPKKGDssAEELKLAtQLtGPVMPVRNVYKKEKARVItE |
| P26639 | S522 | Sugiyama | TARS1 TARS | PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP |
| P26641 | T409 | Sugiyama | EEF1G EF1G PRO1608 | DWQVDyESyTWRKLDPGsEEtQtLVREyFSWEGAFQHVGKA |
| P27348 | S156 | Sugiyama | YWHAQ | DDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLGLALNFSV |
| P27348 | S37 | Sugiyama | YWHAQ | ERyDDMAtCMKAVtEQGAELsNEERNLLsVAyKNVVGGRRS |
| P27695 | S129 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | QELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDE |
| P27695 | S135 | Sugiyama | APEX1 APE APE1 APEX APX HAP1 REF1 | SHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGDEEHDQEG |
| P27797 | S35 | Sugiyama | CALR CRTC | AVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGK |
| P27797 | S40 | Sugiyama | CALR CRTC | AVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssGKFyGDE |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P27797 | T350 | Sugiyama | CALR CRTC | FLITNDEAyAEEFGNETWGVtKAAEKQMKDKQDEEQRLKEE |
| P29144 | S176 | Sugiyama | TPP2 | FDVANNGSsQANKLIKEELQsQVELLNsFEKKYSDPGPVYD |
| P29144 | S183 | Sugiyama | TPP2 | SsQANKLIKEELQsQVELLNsFEKKYSDPGPVYDCLVWHDG |
| P29401 | S276 | Sugiyama | TKT | sWHGKPLPKNMAEQIIQEIysQIQsKKKILAtPPQEDAPsV |
| P29401 | S280 | Sugiyama | TKT | KPLPKNMAEQIIQEIysQIQsKKKILAtPPQEDAPsVDIAN |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | S548 | Sugiyama | TKT | NIRVLDPFTIKPLDRKLILDsARAtKGRILTVEDHYYEGGI |
| P29401 | T342 | Sugiyama | TKT | GQALAKLGHAsDRIIALDGDtKNstFsEIFKKEHPDRFIEC |
| P29692 | S37 | Sugiyama | EEF1D EF1D | KYDDAERRFyEQMNGPVAGAsRQENGAsVILRDIARARENI |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S74 | Sugiyama | EEF1D EF1D | RENIQKsLAGssGPGAssGtsGDHGELVVRIAsLEVENQsL |
| P29692 | T129 | Sugiyama | EEF1D EF1D | EARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPA |
| P30041 | S186 | Sugiyama | PRDX6 AOP2 KIAA0106 | SLQLTAEKRVAtPVDWKDGDsVMVLPtIPEEEAKKLFPKGV |
| P30041 | T192 | Sugiyama | PRDX6 AOP2 KIAA0106 | EKRVAtPVDWKDGDsVMVLPtIPEEEAKKLFPKGVFtKELP |
| P30041 | T48 | Sugiyama | PRDX6 AOP2 KIAA0106 | FLGDSWGILFSHPRDFtPVCttELGRAAKLAPEFAKRNVKL |
| P30041 | T95 | Sugiyama | PRDX6 AOP2 KIAA0106 | SVEDHLAWSKDINAyNCEEPtEKLPFPIIDDRNRELAILLG |
| P30043 | S202 | Sugiyama | BLVRB FLR SCAN | GHFMLRCLttDEyDGHstyPsHQyQ________________ |
| P30044 | S171 | Sugiyama | PRDX5 ACR1 SBBI10 | ADPTGAFGKEtDLLLDDsLVsIFGNRRLKRFsMVVQDGIVK |
| P30050 | S26 | Sugiyama | RPL12 | DPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDDI |
| P30050 | T25 | Sugiyama | RPL12 | FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD |
| P30085 | S180 | Sugiyama | CMPK1 CMK CMPK UCK UMK UMPK | KPIIDLyEEMGKVKKIDASKsVDEVFDEVVQIFDKEG____ |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30086 | S52 | Sugiyama | PEBP1 PBP PEBP | AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD |
| P30086 | S60 | Sugiyama | PEBP1 PBP PEBP | VLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPK |
| P30101 | S163 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | EEFKKFISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYR |
| P30101 | S169 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | ISDKDAsIVGFFDDsFsEAHsEFLKAASNLRDNYRFAHTNV |
| P30101 | S343 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | IPVVAIRTAKGEKFVMQEEFsRDGKALERFLQDyFDGNLKR |
| P30101 | S478 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | ANKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKK |
| P30419 | T122 | Sugiyama | NMT1 NMT | GQGPAKTMEEASKRSyQFWDtQPVPKLGEVVNtHGPVEPDK |
| P30533 | S230 | Sugiyama | LRPAP1 A2MRAP | SDIKGSVLHSRHTELKEKLRsINQGLDRLRRVsHQGystEA |
| P31150 | S316 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM |
| P31327 | S205 | Sugiyama | CPS1 | FEGQPVDFVDPNKQNLIAEVstKDVKVYGKGNPTKVVAVDC |
| P31327 | T326 | Sugiyama | CPS1 | AKTYKMSMANRGQNQPVLNItNKQAFITAQNHGYALDNTLP |
| P31939 | S401 | Sugiyama | ATIC PURH OK/SW-cl.86 | LFGLHLsQKRNNGVVDKSLFsNVVTKNKDLPESALRDLIVA |
| P31939 | S450 | Sugiyama | ATIC PURH OK/SW-cl.86 | SNSVCYAKNGQVIGIGAGQQsRIHCTRLAGDKANyWWLRHH |
| P31943 | S285 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | NyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDI |
| P31943 | T286 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | yCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAtENDIy |
| P31946 | S147 | Sugiyama | YWHAB | YFRyLsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHP |
| P31946 | S158 | Sugiyama | YWHAB | DNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLGLALNFSV |
| P31946 | S39 | Sugiyama | YWHAB | ERyDDMAAAMKAVtEQGHELsNEERNLLsVAyKNVVGARRS |
| P32119 | T142 | Sugiyama | PRDX2 NKEFB TDPX1 | EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF |
| P32929 | S61 | Sugiyama | CTH | ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA |
| P32969 | S135 | Sugiyama | RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 | RNFLGEKYIRRVRMRPGVACsVsQAQKDELILEGNDIELVS |
| P33316 | S164 | Sugiyama | DUT | YTIPPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDV |
| P33991 | T854 | Sugiyama | MCM4 CDC21 | AITKDMFEEALRALADDDFLtVtGKtVRLL___________ |
| P33991 | T856 | Sugiyama | MCM4 CDC21 | TKDMFEEALRALADDDFLtVtGKtVRLL_____________ |
| P33991 | T859 | Sugiyama | MCM4 CDC21 | MFEEALRALADDDFLtVtGKtVRLL________________ |
| P34896 | S381 | Sugiyama | SHMT1 | VDLRSKGTDGGRAEKVLEACsIACNKNTCPGDRSALRPSGL |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34931 | T228 | Sugiyama | HSPA1L | DVSILTIDDGIFEVKAtAGDtHLGGEDFDNRLVsHFVEEFK |
| P34931 | T39 | Sugiyama | HSPA1L | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P34931 | T40 | Sugiyama | HSPA1L | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P35221 | S668 | Sugiyama | CTNNA1 | FDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEQKAKIAEQV |
| P35221 | S690 | Sugiyama | CTNNA1 | RAIMAQLPQEQKAKIAEQVAsFQEEKSKLDAEVSKWDDSGN |
| P35241 | S249 | Sugiyama | RDX | EHDDKLTPKIGFPWSEIRNIsFNDKKFVIKPIDKKAPDFVF |
| P35579 | S1290 | Sugiyama | MYH9 | ELADKVTKLQVELDNVtGLLsQsDSKSSKLTKDFsALEsQL |
| P35579 | S1892 | Sugiyama | MYH9 | LKQLKRQLEEAEEEAQRANAsRRKLQRELEDAtEtADAMNR |
| P35579 | S96 | Sugiyama | MYH9 | NPPKFSKVEDMAELtCLNEAsVLHNLKERYYSGLIYTYSGL |
| P35579 | T90 | Sugiyama | MYH9 | DDIQKMNPPKFSKVEDMAELtCLNEAsVLHNLKERYYSGLI |
| P35580 | S100 | Sugiyama | MYH10 | NPPKFSKVEDMAELtCLNEAsVLHNLKDRYYSGLIYTYSGL |
| P35580 | T94 | Sugiyama | MYH10 | DDIQKMNPPKFSKVEDMAELtCLNEAsVLHNLKDRYYSGLI |
| P35606 | T357 | Sugiyama | COPB2 | DGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVCGDGEYII |
| P35613 | S278 | Sugiyama | BSG UNQ6505/PRO21383 | ITDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQ |
| P35637 | S346 | Sugiyama | FUS TLS | TDRETGKLKGEAtVsFDDPPsAKAAIDWFDGKEFsGNPIKV |
| P35637 | S360 | Sugiyama | FUS TLS | sFDDPPsAKAAIDWFDGKEFsGNPIKVsFATRRADFNRGGG |
| P35637 | S367 | Sugiyama | FUS TLS | AKAAIDWFDGKEFsGNPIKVsFATRRADFNRGGGNGRGGRG |
| P35908 | S191 | Sugiyama | KRT2 KRT2A KRT2E | IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P36578 | T84 | Sugiyama | RPL4 RPL1 | AEsWGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAP |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37802 | T180 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_ |
| P37802 | T190 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________ |
| P38117 | T172 | Sugiyama | ETFB FP585 | QVTLEGDKLKVEREIDGGLEtLRLKLPAVVTADLRLNEPRy |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S549 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P38646 | T120 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV |
| P38646 | T185 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | QIGAFVLMKMKEtAENyLGHtAKNAVItVPAyFNDsQRQAt |
| P38646 | T398 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA |
| P38646 | T86 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | CVAVMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAK |
| P38646 | T94 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | QAKVLENAEGARttPsVVAFtADGERLVGMPAKRQAVtNPN |
| P38646 | Y118 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK |
| P39019 | S93 | Sugiyama | RPS19 | GsMTKIYGGRQRNGVMPsHFsRGsKsVARRVLQALEGLKMV |
| P39019 | T55 | Sugiyama | RPS19 | DtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGsM |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P39023 | S265 | Sugiyama | RPL3 OK/SW-cl.32 | HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY |
| P39687 | S27 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | IHLELRNRtPsDVKELVLDNsRsNEGKLEGLTDEFEELEFL |
| P40925 | S153 | Sugiyama | MDH1 MDHA | ANtNCLtAsKSAPSIPKENFsCLtRLDHNRAKAQIALKLGV |
| P40925 | T225 | Sugiyama | MDH1 MDHA | KEVGVyEALKDDsWLKGEFVttVQQRGAAVIKARKLssAMS |
| P40926 | S69 | Sugiyama | MDH2 | LVsRLtLyDIAHtPGVAADLsHIEtKAAVKGyLGPEQLPDC |
| P40926 | T227 | Sugiyama | MDH2 | PLISQCtPKVDFPQDQLtALtGRIQEAGtEVVKAKAGAGsA |
| P40926 | T73 | Sugiyama | MDH2 | LtLyDIAHtPGVAADLsHIEtKAAVKGyLGPEQLPDCLKGC |
| P42677 | S78 | Sugiyama | RPS27 MPS1 | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| P43034 | S152 | Sugiyama | PAFAH1B1 LIS1 MDCR MDS PAFAHA | IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM |
| P43490 | S241 | Sugiyama | NAMPT PBEF PBEF1 | VAGLALIKKYYGTKDPVPGysVPAAEHStItAWGKDHEKDA |
| P43490 | T249 | Sugiyama | NAMPT PBEF PBEF1 | KYYGTKDPVPGysVPAAEHStItAWGKDHEKDAFEHIVTQF |
| P43490 | T251 | Sugiyama | NAMPT PBEF PBEF1 | YGTKDPVPGysVPAAEHStItAWGKDHEKDAFEHIVTQFSS |
| P43490 | Y240 | Sugiyama | NAMPT PBEF PBEF1 | TVAGLALIKKYYGTKDPVPGysVPAAEHStItAWGKDHEKD |
| P45974 | S783 | Sugiyama | USP5 ISOT | IDDLDAEAAMDISEGRsAADsIsEsVPVGPKVRDGPGKYQL |
| P46060 | S24 | Sugiyama | RANGAP1 KIAA1835 SD | EDIAKLAETLAKTQVAGGQLsFKGKSLKLNTAEDAKDVIKE |
| P46087 | S40 | Sugiyama | NOP2 NOL1 NSUN1 | KQKGAEtELVRFLPAVsDENsKRLsSRARKRAAKRRLGsVE |
| P46459 | S31 | Sugiyama | NSF | CPTDELsLtNCAVVNEKDFQsGQHVIVRTSPNHRyTFTLKT |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46776 | T72 | Sugiyama | RPL27A | yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK |
| P46777 | S172 | Sugiyama | RPL5 MSTP030 | RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA |
| P46777 | S176 | Sugiyama | RPL5 MSTP030 | GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46779 | T80 | Sugiyama | RPL28 | VVVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKN |
| P46779 | T81 | Sugiyama | RPL28 | VVVIKRRSGQRKPAtsyVRttINKNARAtLsSIRHMIRKNK |
| P46782 | S75 | Sugiyama | RPS5 | RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH |
| P47756 | S90 | Sugiyama | CAPZB | SyRsPWSNKyDPPLEDGAMPsARLRKLEVEANNAFDQYRDL |
| P48643 | S154 | Sugiyama | CCT5 CCTE KIAA0098 | ADGYEQAARVAIEHLDKISDsVLVDIKDTEPLIQTAKTTLG |
| P48643 | S79 | Sugiyama | CCT5 CCTE KIAA0098 | KMMVDKDGDVtVTNDGATILsMMDVDHQIAKLMVELSKSQD |
| P48643 | T69 | Sugiyama | CCT5 CCTE KIAA0098 | RtsLGPNGLDKMMVDKDGDVtVTNDGATILsMMDVDHQIAK |
| P48668 | S176 | Sugiyama | KRT6C KRT6E | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P48739 | S165 | Sugiyama | PITPNB | DRSQVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsP |
| P48739 | T168 | Sugiyama | PITPNB | QVEPADyKADEDPALFQsVKtKRGPLGPNWKKELANsPDCP |
| P48741 | T228 | Sugiyama | HSPA7 HSP70B | DVSVLSIDAGVFEVKAtAGDtHLGGEDFDNRLVNHFMEEFR |
| P49321 | S659 | Sugiyama | NASP | IEELKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsst |
| P49321 | S662 | Sugiyama | NASP | LKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsstsGF |
| P49327 | T1061 | Sugiyama | FASN FAS | SAKHGLyLPTRVtAIHIDPAtHRQKLyTLQDKAQVADVVVS |
| P49327 | T2215 | Sugiyama | FASN FAS | DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN |
| P49588 | S188 | Sugiyama | AARS1 AARS | PGNMKDNFWEMGDtGPCGPCsEIHyDRIGGRDAAHLVNQDD |
| P49589 | S305 | Sugiyama | CARS1 CARS | KLVPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKA |
| P49589 | S307 | Sugiyama | CARS1 CARS | VPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKASK |
| P49589 | S312 | Sugiyama | CARS1 CARS | GDQKALQEGEGDLsIsADRLsEKRSPNDFALWKASKPGEPS |
| P49590 | S127 | Sugiyama | HARS2 HARSL HARSR HO3 | KYGEDSGLMYDLKDQGGELLsLRYDLTVPFARYLAMNKVKK |
| P49792 | S1894 | Sugiyama | RANBP2 NUP358 | FQGSSNTEFKSTKEGFSIPVsADGFKFGIsEPGNQEKKSEK |
| P50395 | S316 | Sugiyama | GDI2 RABGDIB | QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM |
| P50395 | T205 | Sugiyama | GDI2 RABGDIB | TGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsPYL |
| P50416 | S612 | Sugiyama | CPT1A CPT1 | SMTRLFREGRTETVRSCTTEsCDFVRAMVDPAQTVEQRLKL |
| P50454 | S138 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | LSNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEH |
| P50454 | S139 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | SNSTARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHS |
| P50454 | S149 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | KLGsRLyGPssVsFADDFVRssKQHYNCEHSKINFRDKRSA |
| P50454 | T314 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | MGKMQKKAVAISLPKGVVEVtHDLQKHLAGLGLtEAIDKNK |
| P50502 | S181 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | LQKPNAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| P50990 | S373 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | SEVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVD |
| P50990 | S380 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | VVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDDGVNtFK |
| P50990 | T374 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | EVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDD |
| P50991 | T69 | Sugiyama | CCT4 CCTD SRB | RtsLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAAR |
| P50991 | T71 | Sugiyama | CCT4 CCTD SRB | sLGPKGMDKMIQDGKGDVtItNDGAtILKQMQVLHPAARML |
| P51149 | T168 | Sugiyama | RAB7A RAB7 | NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE |
| P51991 | S375 | Sugiyama | HNRNPA3 HNRPA3 | ssGsPyGGGyGsGGGsGGyGsRRF_________________ |
| P52209 | S405 | Sugiyama | PGD PGDH | ELQNLLLDDFFKSAVENCQDsWRRAVSTGVQAGIPMPCFTT |
| P52597 | S107 | Sugiyama | HNRNPF HNRPF | KSHRTEMDWVLKHsGPNsADsANDGFVRLRGLPFGCTKEEI |
| P52597 | S279 | Sugiyama | HNRNPF HNRPF | LFGRDLsyCLsGMyDHRYGDsEFtVQsTTGHCVHMRGLPYK |
| P52597 | S285 | Sugiyama | HNRNPF HNRPF | syCLsGMyDHRYGDsEFtVQsTTGHCVHMRGLPYKAtENDI |
| P52597 | T282 | Sugiyama | HNRNPF HNRPF | RDLsyCLsGMyDHRYGDsEFtVQsTTGHCVHMRGLPYKAtE |
| P52907 | S215 | Sugiyama | CAPZA1 | QVHYYEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENA |
| P52907 | S219 | Sugiyama | CAPZA1 | YEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAENEy |
| P52907 | T217 | Sugiyama | CAPZA1 | HYYEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAEN |
| P52907 | T224 | Sugiyama | CAPZA1 | VQLVSHKDVQDsLtVsNEAQtAKEFIKIIENAENEyQTAIs |
| P52948 | S683 | Sugiyama | NUP98 ADAR2 | IAKPIPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEG |
| P52948 | T687 | Sugiyama | NUP98 ADAR2 | IPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEGssEE |
| P53365 | T76 | Sugiyama | ARFIP2 POR1 | GGSGDGLIPTGSGRHPSHsTtPSGPGDEVARGIAGEKFDIV |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P53999 | S15 | Sugiyama | SUB1 PC4 RPO2TC1 | ______MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEK |
| P53999 | S17 | Sugiyama | SUB1 PC4 RPO2TC1 | ____MPKSKELVsssssGsDsDsEVDKKLKRKKQVAPEKPV |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P54652 | T38 | Sugiyama | HSPA2 | CVGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKN |
| P54652 | T39 | Sugiyama | HSPA2 | VGVFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQ |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P55036 | S266 | Sugiyama | PSMD4 MCB1 | AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ |
| P55060 | S931 | Sugiyama | CSE1L CAS XPO2 | KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL |
| P55060 | T341 | Sugiyama | CSE1L CAS XPO2 | LASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEA |
| P55072 | S37 | Sugiyama | VCP HEL-220 HEL-S-70 | LKQKNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTV |
| P55072 | S40 | Sugiyama | VCP HEL-220 HEL-S-70 | KNRPNRLIVDEAINEDNsVVsLSQPKMDELQLFRGDTVLLK |
| P55072 | T14 | Sugiyama | VCP HEL-220 HEL-S-70 | _______MAsGADsKGDDLstAILKQKNRPNRLIVDEAINE |
| P55769 | S29 | Sugiyama | SNU13 NHP2L1 | KAyPLADAHLTKKLLDLVQQsCNyKQLRKGANEATKTLNRG |
| P55795 | S282 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | RDLNyCFsGMsDHRyGDGGssFQstTGHCVHMRGLPYRATE |
| P55795 | S285 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | NyCFsGMsDHRyGDGGssFQstTGHCVHMRGLPYRATENDI |
| P55957 | S78 | Sugiyama | BID | QtDGNRssHsRLGRIEADsEsQEDIIRNIARHLAQVGDsMD |
| P56192 | S127 | Sugiyama | MARS1 MARS | GKKGEDVLGSVRRALTHIDHsLSRQNCPFLAGETESLADIV |
| P56192 | S812 | Sugiyama | MARS1 MARS | GHQIGTVSPLFQKLENDQIEsLRQRFGGGQAKtsPKPAVVE |
| P56537 | T91 | Sugiyama | EIF6 EIF3A ITGB4BP OK/SW-cl.27 | LVPNNTTDQELQHIRNSLPDtVQIRRVEERLSALGNVTTCN |
| P57721 | S173 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | KEIREstGAQVQVAGDMLPNstERAVTISGTPDAIIQCVKQ |
| P57721 | S82 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | GKKGETVKKMREESGARINIsEGNCPERIVTITGPTDAIFK |
| P57721 | T174 | Sugiyama | PCBP3 PCBP3-OT1 PCBP3OT | EIREstGAQVQVAGDMLPNstERAVTISGTPDAIIQCVKQI |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | S97 | Sugiyama | TPI1 TPI | GEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELIGQKVAHA |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60660 | T22 | Sugiyama | MYL6 | CDFTEDQTAEFKEAFQLFDRtGDGKILysQCGDVMRALGQN |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S365 | Sugiyama | ACTB | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | S60 | Sugiyama | ACTB | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P60709 | T106 | Sugiyama | ACTB | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P60709 | T202 | Sugiyama | ACTB | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P60709 | T249 | Sugiyama | ACTB | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P60709 | T297 | Sugiyama | ACTB | TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI |
| P60709 | T304 | Sugiyama | ACTB | KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst |
| P60709 | T318 | Sugiyama | ACTB | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60709 | Y53 | Sugiyama | ACTB | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P60763 | T161 | Sugiyama | RAC3 | QGLAMAREIGSVKyLECsALtQRGLKtVFDEAIRAVLCPPP |
| P60842 | S189 | Sugiyama | EIF4A1 DDX2A EIF4A | RYLSPKYIKMFVLDEADEMLsRGFKDQIyDIFQKLNsNtQV |
| P60842 | S78 | Sugiyama | EIF4A1 DDX2A EIF4A | IQQRAILPCIKGyDVIAQAQsGtGKTATFAISILQQIELDL |
| P61247 | S236 | Sugiyama | RPS3A FTE1 MFTL | KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61254 | S23 | Sugiyama | RPL26 | FNPFVtsDRsKNRKRHFNAPsHIRRKIMssPLSKELRQKYN |
| P61254 | T8 | Sugiyama | RPL26 | _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK |
| P61313 | S100 | Sugiyama | RPL15 EC45 TCBAP0781 | tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW |
| P61353 | T94 | Sugiyama | RPL27 | VyNyNHLMPtRysVDIPLDKtVVNKDVFRDPALKRKARREA |
| P61604 | S64 | Sugiyama | HSPE1 | AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD |
| P61769 | S108 | Sugiyama | B2M CDABP0092 HDCMA22P | TEFTPTEKDEYACRVNHVtLsQPKIVKWDRDM_________ |
| P61769 | T106 | Sugiyama | B2M CDABP0092 HDCMA22P | YYTEFTPTEKDEYACRVNHVtLsQPKIVKWDRDM_______ |
| P61978 | S420 | Sugiyama | HNRNPK HNRPK | GsIIGKGGQRIKQIRHEsGAsIKIDEPLEGsEDRIITItGt |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61978 | S81 | Sugiyama | HNRNPK HNRPK | GGKNIKALRtDyNAsVsVPDssGPERILsISADIETIGEIL |
| P61981 | S38 | Sugiyama | YWHAG | ERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKNVVGARRS |
| P61981 | T31 | Sugiyama | YWHAG | ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN |
| P62136 | S11 | Sugiyama | PPP1CA PPP1A | __________MsDsEKLNLDsIIGRLLEVQGsRPGKNVQLT |
| P62191 | T56 | Sugiyama | PSMC1 | KKKKTKGPDAASKLPLVtPHtQCRLKLLKLERIKDYLLMEE |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S117 | Sugiyama | YWHAE | CCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAEFAt |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62263 | S137 | Sugiyama | RPS14 PRO2640 | RALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL______ |
| P62263 | S70 | Sugiyama | RPS14 PRO2640 | KETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGI |
| P62266 | S45 | Sugiyama | RPS23 | KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62277 | S12 | Sugiyama | RPS13 | _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD |
| P62316 | T40 | Sugiyama | SNRPD2 SNRPD1 | EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD |
| P62424 | S209 | Sugiyama | RPL7A SURF-3 SURF3 | RLGRLVHRKTCTtVAFTQVNsEDKGALAKLVEAIRTNyNDR |
| P62495 | T298 | Sugiyama | ETF1 ERF1 RF1 SUP45L1 | VKFIQEKKLIGRyFDEIsQDtGKyCFGVEDTLKALEMGAVE |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | S62 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P62736 | T251 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P62736 | T320 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62736 | Y55 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P62826 | S150 | Sugiyama | RAN ARA24 OK/SW-cl.81 | KVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARKLIG |
| P62826 | T32 | Sugiyama | RAN ARA24 OK/SW-cl.81 | KLVLVGDGGtGKttFVKRHLtGEFEKKyVATLGVEVHPLVF |
| P62917 | S138 | Sugiyama | RPL8 | EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI |
| P63000 | T161 | Sugiyama | RAC1 TC25 MIG5 | QGLAMAKEIGAVKyLECsALtQRGLKtVFDEAIRAVLCPPP |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | T30 | Sugiyama | YWHAZ | AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN |
| P63167 | S21 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | MCDRKAVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAH |
| P63167 | T26 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF |
| P63220 | S68 | Sugiyama | RPS21 | GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____ |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S365 | Sugiyama | ACTG1 ACTG | ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________ |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | S60 | Sugiyama | ACTG1 ACTG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEHGIVTNWD |
| P63261 | T106 | Sugiyama | ACTG1 ACTG | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P63261 | T202 | Sugiyama | ACTG1 ACTG | GRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVALD |
| P63261 | T249 | Sugiyama | ACTG1 ACTG | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPsFLGM |
| P63261 | T297 | Sugiyama | ACTG1 ACTG | TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI |
| P63261 | T304 | Sugiyama | ACTG1 ACTG | KCDVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPst |
| P63261 | T318 | Sugiyama | ACTG1 ACTG | VLsGGttMyPGIADRMQKEItALAPstMKIKIIAPPERKYs |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63261 | Y53 | Sugiyama | ACTG1 ACTG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIEH |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | S61 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P63267 | T250 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P63267 | T319 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P63267 | Y54 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P67809 | S136 | Sugiyama | YBX1 NSEP1 YB1 | GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR |
| P67809 | T108 | Sugiyama | YBX1 NSEP1 YB1 | QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP |
| P67809 | Y99 | Sugiyama | YBX1 NSEP1 YB1 | DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | S62 | Sugiyama | ACTC1 ACTC | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68032 | T251 | Sugiyama | ACTC1 ACTC | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68032 | T320 | Sugiyama | ACTC1 ACTC | VLSGGtTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68032 | Y55 | Sugiyama | ACTC1 ACTC | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68104 | T432 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | S62 | Sugiyama | ACTA1 ACTA | HQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEHGIItNWD |
| P68133 | T251 | Sugiyama | ACTA1 ACTA | tAAssssLEKsyELPDGQVItIGNERFRCPETLFQPSFIGM |
| P68133 | T320 | Sugiyama | ACTA1 ACTA | VMSGGTTMYPGIADRMQKEItALAPstMKIKIIAPPERKYS |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68133 | Y55 | Sugiyama | ACTA1 ACTA | sIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIEH |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | S54 | Sugiyama | TUBA1B | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P68363 | T334 | Sugiyama | TUBA1B | ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG |
| P68363 | T337 | Sugiyama | TUBA1B | LLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVGINy |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T80 | Sugiyama | TUBA1B | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| P68363 | T82 | Sugiyama | TUBA1B | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| P68363 | Y83 | Sugiyama | TUBA1B | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| P78371 | S60 | Sugiyama | CCT2 99D8.1 CCTB | KSTLGPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPA |
| P78371 | T246 | Sugiyama | CCT2 99D8.1 CCTB | VNQPKRIENAKILIANtGMDtDKIKIFGsRVRVDstAKVAE |
| P78371 | T474 | Sugiyama | CCT2 99D8.1 CCTB | AGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAILGIT |
| P78371 | T64 | Sugiyama | CCT2 99D8.1 CCTB | GPKGMDKILLsSGRDAsLMVtNDGAtILKNIGVDNPAAKVL |
| P78417 | S23 | Sugiyama | GSTO1 GSTTLP28 | GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK |
| P80192 | S308 | GPS6|EPSD | MAP3K9 MLK1 PRKE1 | KILKITDFGLAREWHRttKMsAAGtYAWMAPEVIRASMFSK |
| P80192 | T304 | GPS6|EPSD | MAP3K9 MLK1 PRKE1 | DLSNKILKITDFGLAREWHRttKMsAAGtYAWMAPEVIRAS |
| P80192 | T305 | EPSD | MAP3K9 MLK1 PRKE1 | LSNKILKITDFGLAREWHRttKMsAAGtYAWMAPEVIRASM |
| P80192 | T312 | GPS6|SIGNOR|iPTMNet|EPSD | MAP3K9 MLK1 PRKE1 | ITDFGLAREWHRttKMsAAGtYAWMAPEVIRASMFSKGSDV |
| P84098 | S37 | Sugiyama | RPL19 | CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV |
| P84098 | T29 | Sugiyama | RPL19 | RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL |
| P99999 | S48 | Sugiyama | CYCS CYC | KTGPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEY |
| Q00610 | S886 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | IHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsRVVG |
| Q00610 | T875 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | LKLLLPWLEARIHEGCEEPAtHNALAKIyIDsNNNPERFLR |
| Q00613 | S363 | Sugiyama | HSF1 HSTF1 | AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE |
| Q00613 | T367 | Sugiyama | HSF1 HSTF1 | ALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNELSDH |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01082 | S1666 | Sugiyama | SPTBN1 SPTB2 | ETVHQLSKTSRALVADSHPEsERIsMRQSKVDKLYAGLKDL |
| Q01082 | S1670 | Sugiyama | SPTBN1 SPTB2 | QLSKTSRALVADSHPEsERIsMRQSKVDKLYAGLKDLAEER |
| Q01082 | S446 | Sugiyama | SPTBN1 SPTB2 | RFDRKAAMRETWLsENQRLVsQDNFGFDLPAVEAAtKKHEA |
| Q01082 | T1386 | Sugiyama | SPTBN1 SPTB2 | ESTTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSD |
| Q01082 | T461 | Sugiyama | SPTBN1 SPTB2 | NQRLVsQDNFGFDLPAVEAAtKKHEAIETDIAAYEERVQAV |
| Q01105 | S165 | Sugiyama | SET | PyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQ |
| Q01105 | S166 | Sugiyama | SET | yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q01518 | S431 | Sugiyama | CAP1 CAP | NKTDGCHAYLSKNSLDCEIVsAKSSEMNVLIPTEGGDFNEF |
| Q01518 | T165 | Sugiyama | CAP1 CAP | AMAPKPGPYVKEMNDAAMFytNRVLKEYKDVDKKHVDWVKA |
| Q01546 | S196 | Sugiyama | KRT76 KRT2B KRT2P | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE |
| Q02543 | T101 | Sugiyama | RPL18A | WLRYDsRSGtHNMYREyRDLttAGAVtQCyRDMGARHRARA |
| Q02543 | T107 | Sugiyama | RPL18A | RSGtHNMYREyRDLttAGAVtQCyRDMGARHRARAHsIQIM |
| Q02878 | S255 | Sugiyama | RPL6 TXREB1 | tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF |
| Q02952 | S1251 | Sugiyama | AKAP12 AKAP250 | EETKEQSKMEDtLEHTDKEVsVEtVsILsKTEGtQEADQyA |
| Q02952 | S1256 | Sugiyama | AKAP12 AKAP250 | QSKMEDtLEHTDKEVsVEtVsILsKTEGtQEADQyADEKTK |
| Q02952 | T1254 | Sugiyama | AKAP12 AKAP250 | KEQSKMEDtLEHTDKEVsVEtVsILsKTEGtQEADQyADEK |
| Q04637 | S1058 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | PPIsRGLPLVDDGGWNtVPIsKGSRPIDTSRLTKItKPGsI |
| Q04637 | S1440 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | QKVEyTLGEEsEAPGQRALPsEELNRQLEKLLKEGSSNQRV |
| Q04637 | T1054 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | GPPGPPIsRGLPLVDDGGWNtVPIsKGSRPIDTSRLTKItK |
| Q04695 | S277 | Sugiyama | KRT17 | RDQYEKMAEKNRKDAEDWFFsKTEELNREVATNsELVQSGK |
| Q04837 | S79 | Sugiyama | SSBP1 SSBP | LATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPGLRDVAy |
| Q04917 | S38 | Sugiyama | YWHAH YWHA1 | ERyDDMAsAMKAVtELNEPLsNEDRNLLsVAyKNVVGARRS |
| Q05639 | T432 | Sugiyama | EEF1A2 EEF1AL STN | VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT |
| Q05682 | T169 | Sugiyama | CALD1 CAD CDM | KEEKsESRQERyEIEETEtVtKSYQKNDWRDAEENKKEDKE |
| Q06210 | S353 | Sugiyama | GFPT1 GFAT GFPT | QIMKGNFSSFMQKEIFEQPEsVVNtMRGRVNFDDYTVNLGG |
| Q06210 | T357 | Sugiyama | GFPT1 GFAT GFPT | GNFSSFMQKEIFEQPEsVVNtMRGRVNFDDYTVNLGGLKDH |
| Q06265 | S287 | Sugiyama | EXOSC9 PMSCL1 | KALENDQKVRKEGGKFGFAEsIANQRITAFKMEKAPIDtsD |
| Q06323 | S55 | Sugiyama | PSME1 IFI5111 | KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE |
| Q06830 | S32 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | APNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTFVC |
| Q06830 | T143 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF |
| Q06830 | T166 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | DLPVGRsVDEtLRLVQAFQFtDKHGEVCPAGWKPGsDtIKP |
| Q07020 | S140 | Sugiyama | RPL18 | ILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAPGtPH |
| Q07020 | S62 | Sugiyama | RPL18 | tFNQVVLKRLFMSRtNRPPLsLsRMIRKMKLPGRENKtAVV |
| Q07020 | T136 | Sugiyama | RPL18 | AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP |
| Q07021 | S210 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS |
| Q07021 | S87 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | CGCGCGSLHTDGDKAFVDFLsDEIKEERKIQKHKTLPKMsG |
| Q07666 | S117 | Sugiyama | KHDRBS1 SAM68 | MEPENKyLPELMAEKDsLDPsFtHAMQLLtAEIEKIQKGDS |
| Q07666 | T119 | Sugiyama | KHDRBS1 SAM68 | PENKyLPELMAEKDsLDPsFtHAMQLLtAEIEKIQKGDSKK |
| Q07666 | T126 | Sugiyama | KHDRBS1 SAM68 | ELMAEKDsLDPsFtHAMQLLtAEIEKIQKGDSKKDDEENyL |
| Q07866 | S389 | Sugiyama | KLC1 KLC KNS2 | YQTKLGPDDPNVAKTKNNLAsCyLKQGKFKQAETLYKEILT |
| Q12792 | S140 | Sugiyama | TWF1 PTK9 | EVFGTVKEDVSLHGYKKyLLsQssPAPLtAAEEELRQIKIN |
| Q12792 | T148 | Sugiyama | TWF1 PTK9 | DVSLHGYKKyLLsQssPAPLtAAEEELRQIKINEVQtDVGV |
| Q12874 | S76 | Sugiyama | SF3A3 SAP61 | NLRDLyDDKDGLRKEELNAIsGPNEFAEFyNRLKQIKEFHR |
| Q12906 | T315 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | CEKEAtDAIGHLDRQQREDItQsAQHALRLAAFGQLHKVLG |
| Q13085 | S1766 | Sugiyama | ACACA ACAC ACC1 ACCA | KGYRYLYLTPQDYKRVsALNsVHCEHVEDEGESRYKITDII |
| Q13112 | S410 | Sugiyama | CHAF1B CAF1A CAF1P60 MPHOSPH7 MPP7 | LNMRtPDtAKKTKsQtHRGssPGPRPVEGtPASRtQDPssP |
| Q13242 | S172 | Sugiyama | SRSF9 SFRS9 SRP30C | yLRKEDMEYALRKLDDTKFRsHEGEtsYIRVYPERstsYGY |
| Q13242 | T177 | Sugiyama | SRSF9 SFRS9 SRP30C | DMEYALRKLDDTKFRsHEGEtsYIRVYPERstsYGYsRsRS |
| Q13310 | S212 | Sugiyama | PABPC4 APP1 PABP4 | NVyIKNFGEEVDDEsLKELFsQFGKTLSVKVMRDPNGKSKG |
| Q13492 | S565 | Sugiyama | PICALM CALM | ANLVGNLGIGNGTTKNDVNWsQPGEKKLtGGSNWQPKVAPT |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13509 | S75 | Sugiyama | TUBB3 TUBB4 | SSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIFGQS |
| Q13509 | T107 | Sugiyama | TUBB3 TUBB4 | PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC |
| Q13509 | T72 | Sugiyama | TUBB3 TUBB4 | NEASSHKYVPRAILVDLEPGtMDsVRSGAFGHLFRPDNFIF |
| Q13509 | Y106 | Sugiyama | TUBB3 TUBB4 | RPDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECEN |
| Q13526 | S126 | Sugiyama | PIN1 | LAsQFSDCSsAKARGDLGAFsRGQMQKPFEDAsFALRTGEM |
| Q13765 | S132 | Sugiyama | NACA HSD48 | YKSPAsDtyIVFGEAKIEDLsQQAQLAAAEKFKVQGEAVsN |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q13885 | S75 | Sugiyama | TUBB2A TUBB2 | AGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q13885 | T107 | Sugiyama | TUBB2A TUBB2 | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q13885 | T72 | Sugiyama | TUBB2A TUBB2 | NEAAGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| Q13885 | Y106 | Sugiyama | TUBB2A TUBB2 | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14152 | S988 | Sugiyama | EIF3A EIF3S10 KIAA0139 | PRRGPEEDRFsRRGADDDRPsWRNTDDDRPPRRIADEDRGN |
| Q14152 | T1379 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EKDREsLRRTKNEtDEDGWttVRR_________________ |
| Q14204 | S247 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | PKVTDFGDKVEDPTFLNQLQsGVNRWIREIQKVTKLDRDPA |
| Q14240 | S190 | Sugiyama | EIF4A2 DDX2B EIF4F | RYLSPKWIKMFVLDEADEMLsRGFKDQIYEIFQKLNTSIQV |
| Q14240 | S79 | Sugiyama | EIF4A2 DDX2B EIF4F | IQQRAIIPCIKGyDVIAQAQsGtGKTATFAISILQQLEIEF |
| Q14247 | S113 | Sugiyama | CTTN EMS1 | DRMDKsAVGHEyQSKLsKHCsQVDsVRGFGGKFGVQMDRVD |
| Q14247 | S331 | Sugiyama | CTTN EMS1 | GVQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIR |
| Q14247 | S332 | Sugiyama | CTTN EMS1 | VQKDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIRA |
| Q14247 | T344 | Sugiyama | CTTN EMS1 | FEDVtQVssAyQKTVPVEAVtsKtsNIRANFENLAKEKEQE |
| Q14247 | T347 | Sugiyama | CTTN EMS1 | VtQVssAyQKTVPVEAVtsKtsNIRANFENLAKEKEQEDRR |
| Q14444 | S97 | Sugiyama | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 | DYQERMNKGERLNQDQLDAVsKyQEVtNNLEFAKELQRsFM |
| Q14568 | S50 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL |
| Q14568 | S52 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14568 | T171 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | ITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILHLK |
| Q14677 | S164 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | RLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSKW |
| Q14677 | T265 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | sPKGEFKDEEETVTTKHIHItQATEttttRHKRTANPsKtI |
| Q14677 | T272 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | DEEETVTTKHIHItQATEttttRHKRTANPsKtIDLGAAAH |
| Q14697 | S45 | Sugiyama | GANAB G2AN KIAA0088 | VCLGITLAVDRSNFKtCEEssFCKRQRsIRPGLsPyRALLD |
| Q14697 | T40 | Sugiyama | GANAB G2AN KIAA0088 | LAFLGVCLGITLAVDRSNFKtCEEssFCKRQRsIRPGLsPy |
| Q14847 | S194 | Sugiyama | LASP1 MLN50 | PQQQPVAQsYGGyKEPAAPVsIQRsAPGGGGKRYRAVYDYS |
| Q14CN4 | S138 | Sugiyama | KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 | IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN |
| Q15056 | S110 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK |
| Q15056 | S14 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | _______MADFDtyDDRAyssFGGGRGsRGsAGGHGsRSQK |
| Q15056 | T100 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | KFKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRK |
| Q15056 | Y101 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | FKGFCyVEFDEVDsLKEALtyDGALLGDRsLRVDIAEGRKQ |
| Q15084 | S389 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | FALLKGsFsEQGINEFLRELsFGRGstAPVGGGAFPtIVER |
| Q15293 | S80 | Sugiyama | RCN1 RCN | HEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGDGFVt |
| Q15293 | T100 | Sugiyama | RCN1 RCN | sKERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNV |
| Q15293 | T101 | Sugiyama | RCN1 RCN | KERLGKIVDRIDNDGDGFVttEELKtWIKRVQKRyIFDNVA |
| Q15293 | T76 | Sugiyama | RCN1 RCN | FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD |
| Q15365 | S141 | Sugiyama | PCBP1 | KEIREstGAQVQVAGDMLPNstERAITIAGVPQSVTECVKQ |
| Q15365 | S50 | Sugiyama | PCBP1 | GKKGESVKRIREEsGARINIsEGNCPERIItLTGPTNAIFK |
| Q15365 | T142 | Sugiyama | PCBP1 | EIREstGAQVQVAGDMLPNstERAITIAGVPQSVTECVKQI |
| Q15366 | S141 | Sugiyama | PCBP2 | KEIREstGAQVQVAGDMLPNstERAITIAGIPQSIIECVKQ |
| Q15366 | S50 | Sugiyama | PCBP2 | GKKGESVKKMREESGARINIsEGNCPERIITLAGPTNAIFK |
| Q15366 | T142 | Sugiyama | PCBP2 | EIREstGAQVQVAGDMLPNstERAITIAGIPQSIIECVKQI |
| Q15459 | T124 | Sugiyama | SF3A1 SAP114 | GKAQEPSAAIPKVMQQQQQTtQQQLPQKVQAQVIQETIVPK |
| Q16222 | S484 | Sugiyama | UAP1 SPAG2 | TADVNHNLKDANDVPIQCEIsPLISYAGEGLEsyVADKEFH |
| Q16222 | S496 | Sugiyama | UAP1 SPAG2 | DVPIQCEIsPLISYAGEGLEsyVADKEFHAPLIIDENGVHE |
| Q16222 | Y497 | Sugiyama | UAP1 SPAG2 | VPIQCEIsPLISYAGEGLEsyVADKEFHAPLIIDENGVHEL |
| Q16775 | T291 | Sugiyama | HAGH GLO2 HAGH1 | PFMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD___ |
| Q16775 | T292 | Sugiyama | HAGH GLO2 HAGH1 | FMRVREKTVQQHAGETDPVttMRAVRREKDQFKMPRD____ |
| Q32P51 | S95 | Sugiyama | HNRNPA1L2 HNRNPA1L | TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| Q3SY84 | S143 | Sugiyama | KRT71 K6IRS1 KB34 KRT6IRS1 | IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q3ZCM7 | S75 | Sugiyama | TUBB8 | SGGRYVPRAVLVDLEPGtMDsVRSGPFGQVFRPDNFIFGQC |
| Q562R1 | T250 | Sugiyama | ACTBL2 | RAAAssSPERsyELPDGQVItIGNERFRCPEAIFQPSFLGI |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF3 | S158 | Sugiyama | HSP90B2P GRP94B GRP94P1 TRAP1 | NDTFWKEFGTNIKLGVIEDHsNRTCLAKLLRFQSSHHPADI |
| Q58FF6 | T165 | Sugiyama | HSP90AB4P | DHGEPIDRDTKVILHLKEDQtEyLEERWVKEVVKKHPQFIG |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | S408 | Sugiyama | HSP90AB3P HSP90BC | EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| Q58FF7 | S488 | Sugiyama | HSP90AB3P HSP90BC | TYGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIM |
| Q58FF7 | S67 | Sugiyama | HSP90AB3P HSP90BC | ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNPQERTLALV |
| Q58FF7 | T169 | Sugiyama | HSP90AB3P HSP90BC | DHGEPIGRGTKVILHLKEDQtEyLEERRVKEVVKKHsQFIG |
| Q58FF7 | T410 | Sugiyama | HSP90AB3P HSP90BC | IDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK |
| Q58FF8 | S308 | Sugiyama | HSP90AB2P HSP90BB | YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE |
| Q58FF8 | S67 | Sugiyama | HSP90AB2P HSP90BB | ASDALDKIRyEsLtDPsKLDsGKELKIDIIPNTQEHTLTLV |
| Q58FG1 | S251 | Sugiyama | HSP90AA4P HSP90AD HSPCAL2 | EPIDEYCVQQLKEFEGKtLVsVTKEDLELPEDEEEKKKQEE |
| Q5VTE0 | T432 | Sugiyama | EEF1A1P5 EEF1AL3 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| Q5XKE5 | S155 | Sugiyama | KRT79 K6L KB38 KRT6L | IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | S54 | Sugiyama | TUBA3E | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q6PEY2 | T334 | Sugiyama | TUBA3E | ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q6PEY2 | T337 | Sugiyama | TUBA3E | MLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy |
| Q6S8J3 | S1065 | Sugiyama | POTEE A26C1A POTE2 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | T949 | Sugiyama | POTEE A26C1A POTE2 | tAAssssLEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | S54 | Sugiyama | TUBA1A TUBA3 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q71U36 | T334 | Sugiyama | TUBA1A TUBA3 | ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q71U36 | T337 | Sugiyama | TUBA1A TUBA3 | LLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T80 | Sugiyama | TUBA1A TUBA3 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q71U36 | T82 | Sugiyama | TUBA1A TUBA3 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q71U36 | Y83 | Sugiyama | TUBA1A TUBA3 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q71UM5 | S78 | Sugiyama | RPS27L | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| Q7RTS7 | S153 | Sugiyama | KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 | IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE |
| Q7Z3J3 | S919 | Sugiyama | RGPD4 RGP4 | tKGSSNTEFKSTKEGFSIPVsADGFKFGIsEPGNQEKESEK |
| Q7Z794 | S177 | Sugiyama | KRT77 KRT1B | IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| Q86VP6 | S106 | Sugiyama | CAND1 KIAA0829 TIP120 TIP120A | TIVDTLCTNMLSDKEQLRDIsSIGLKTVIGELPPAssGSAL |
| Q86Y46 | S145 | Sugiyama | KRT73 K6IRS3 KB36 KRT6IRS3 | IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q8NBJ7 | S281 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | ADGsANHRARVttRMGNtPDsAsDNLGFRCAADAGRPPGEL |
| Q8NBS9 | S129 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | MEDAKVYVAKVDCtAHsDVCsAQGVRGYPTLKLFKPGQEAV |
| Q8NBS9 | S255 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | EHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDGKKVD |
| Q8NBS9 | T248 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | EQLALGLEHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWF |
| Q8NE71 | S595 | Sugiyama | ABCF1 ABC50 | TKEALTRKQQKCRRKNQDEEsQEAPELLKRPKEYTVRFTFP |
| Q8NFI4 | S181 | Sugiyama | ST13P5 FAM10A5 | LQKPNAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| Q8NHW5 | S307 | Sugiyama | RPLP0P6 | AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________ |
| Q8TAM6 | S280 | Sugiyama | ERMN KIAA1189 | TISYRKIRKGNTKQRIDEFEsMMHL________________ |
| Q8TC07 | S682 | Sugiyama | TBC1D15 | ALPTLSASGARNDsPtQIPVssDVCRLtPA___________ |
| Q8TC07 | S683 | Sugiyama | TBC1D15 | LPTLSASGARNDsPtQIPVssDVCRLtPA____________ |
| Q8WVJ2 | S142 | Sugiyama | NUDCD2 | LTLERFQKENPGFDFsGAEIsGNytKGGPDFsNLEK_____ |
| Q8WVJ2 | T146 | Sugiyama | NUDCD2 | RFQKENPGFDFsGAEIsGNytKGGPDFsNLEK_________ |
| Q8WVJ2 | Y145 | Sugiyama | NUDCD2 | ERFQKENPGFDFsGAEIsGNytKGGPDFsNLEK________ |
| Q92804 | S295 | Sugiyama | TAF15 RBP56 TAF2N | TDKDTGKPKGEAtVsFDDPPsAKAAIDWFDGKEFHGNIIKV |
| Q92878 | S703 | Sugiyama | RAD50 | VCQRVFQtEAELQEVISDLQsKLRLAPDKLKSTESELKKKE |
| Q92878 | T690 | Sugiyama | RAD50 | ITQLTDENQSCCPVCQRVFQtEAELQEVISDLQsKLRLAPD |
| Q92945 | S200 | Sugiyama | KHSRP FUBP2 | IsPDsGGLPERsVsLtGAPEsVQKAKMMLDDIVSRGRGGPP |
| Q92973 | S339 | Sugiyama | TNPO1 KPNB2 MIP1 TRN | SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE |
| Q969M3 | S45 | Sugiyama | YIPF5 FINGER5 YIP1A PP12723 SB140 UNQ3123/PRO10275 | SYDYGGSGGPYSKQYAGyDysQQGRFVPPDMMQPQQPYTGQ |
| Q96AC1 | S255 | Sugiyama | FERMT2 KIND2 MIG2 PLEKHC1 | KMFKPQALLDKAKINQGWLDsSRSLMEQDVKENEALLLRFK |
| Q96AE4 | S52 | Sugiyama | FUBP1 | KDALQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQ |
| Q96AY3 | S523 | Sugiyama | FKBP10 FKBP65 PSEC0056 | ANLFEDMDLNKDGEVPPEEFsTFIKAQVSEGKGRLMPGQDP |
| Q96B36 | S211 | Sugiyama | AKT1S1 PRAS40 | WGFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAE |
| Q96DB5 | S309 | Sugiyama | RMDN1 FAM82B CGI-90 | YPAHTEEDKQIQtEAAQLLTsFSEKN_______________ |
| Q96DB5 | T301 | Sugiyama | RMDN1 FAM82B CGI-90 | FWLMKAKDYPAHTEEDKQIQtEAAQLLTsFSEKN_______ |
| Q96FX7 | T278 | Sugiyama | TRMT61A C14orf172 TRM61 | AGsDtsPFRSGTPMKEAVGHtGyLTFAtKTPG_________ |
| Q96FX7 | T285 | Sugiyama | TRMT61A C14orf172 TRM61 | FRSGTPMKEAVGHtGyLTFAtKTPG________________ |
| Q96FX7 | Y280 | Sugiyama | TRMT61A C14orf172 TRM61 | sDtsPFRSGTPMKEAVGHtGyLTFAtKTPG___________ |
| Q96G46 | T99 | Sugiyama | DUS3L | DGQtADGQtEEAAEPGEQLQtQKRARGQNKGRPHVKPTNYD |
| Q96HE7 | S143 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD |
| Q96HE7 | T148 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | IEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSDNFCEA |
| Q96IR7 | S365 | Sugiyama | HPDL GLOXD1 | GATGFGQGNIRALWQsVQEQsARSQEA______________ |
| Q96IZ0 | S238 | Sugiyama | PAWR PAR4 | PPRTVSGRyKsttsVsEEDVsSRYsRTDRSGFPRYNRDANV |
| Q96PZ0 | T110 | Sugiyama | PUS7 KIAA1897 | sEECEEEESESFADMMKHGLtEADVGItKFVSSHQGFSGIL |
| Q96PZ0 | T117 | Sugiyama | PUS7 KIAA1897 | ESESFADMMKHGLtEADVGItKFVSSHQGFSGILKERysDF |
| Q99426 | S91 | Sugiyama | TBCB CG22 CKAP1 | DALLGsYPVDDGCRIHVIDHsGARLGEyEDVSRVEKytIsQ |
| Q99436 | T273 | Sugiyama | PSMB7 Z | AVLTEKITPLEIEVLEEtVQtMDts________________ |
| Q99497 | S57 | Sugiyama | PARK7 | GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL |
| Q99584 | S32 | Sugiyama | S100A13 | SIETVVTTFFTFARQEGRKDsLsVNEFKELVTQQLPHLLKD |
| Q99584 | S34 | Sugiyama | S100A13 | ETVVTTFFTFARQEGRKDsLsVNEFKELVTQQLPHLLKDVG |
| Q99613 | S754 | Sugiyama | EIF3C EIF3S8 | REHVVAASKAMKMGDWKTCHsFIINEKMNGKVWDLFPEADK |
| Q99666 | S918 | Sugiyama | RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 | tKGSSNTEFKSTKEGFSIPVsADGFKFGIsEPGNQEKKREK |
| Q99733 | S53 | Sugiyama | NAP1L4 NAP2 | QNPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQL |
| Q99733 | T51 | Sugiyama | NAP1L4 NAP2 | VMQNPRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALK |
| Q99733 | Y55 | Sugiyama | NAP1L4 NAP2 | PRVLAALQERLDNVPHtPssyIEtLPKAVKRRINALKQLQV |
| Q99832 | S59 | Sugiyama | CCT7 CCTH NIP7-1 | TLGPRGMDKLIVDGRGKAtIsNDGAtILKLLDVVHPAAKTL |
| Q99832 | T300 | Sugiyama | CCT7 CCTH NIP7-1 | KIHHSGAKVVLSKLPIGDVAtQyFADRDMFCAGRVPEEDLK |
| Q99832 | T351 | Sugiyama | CCT7 CCTH NIP7-1 | QtSVNALSADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCt |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | S54 | Sugiyama | TUBA1C TUBA6 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q9BQE3 | T334 | Sugiyama | TUBA1C TUBA6 | ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q9BQE3 | T337 | Sugiyama | TUBA1C TUBA6 | LLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVGINy |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T80 | Sugiyama | TUBA1C TUBA6 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q9BQE3 | T82 | Sugiyama | TUBA1C TUBA6 | VPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANN |
| Q9BQE3 | Y83 | Sugiyama | TUBA1C TUBA6 | PRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAANNy |
| Q9BSJ8 | S1086 | Sugiyama | ESYT1 FAM62A KIAA0747 MBC2 | MsRERELLGKVQLDLAETDLsQGVARWYDLMDNKDKGss__ |
| Q9BTE6 | S184 | Sugiyama | AARSD1 | DRLPVNVRELsLDDPEVEQVsGRGLPDDHAGPIRVVNIEGV |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BVA1 | S75 | Sugiyama | TUBB2B | tGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVFGQs |
| Q9BVA1 | T107 | Sugiyama | TUBB2B | PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC |
| Q9BVA1 | T72 | Sugiyama | TUBB2B | NEAtGNKYVPRAILVDLEPGtMDsVRsGPFGQIFRPDNFVF |
| Q9BVA1 | Y106 | Sugiyama | TUBB2B | RPDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESES |
| Q9BWD1 | S208 | Sugiyama | ACAT2 ACTL | RTENAQKAGHFDKEIVPVLVstRKGLIEVKtDEFPRHGsNI |
| Q9BX68 | S57 | Sugiyama | HINT2 | GNEVAKAQQAtPGGAAPtIFsRILDKsLPADILyEDQQCLV |
| Q9BXP5 | T702 | Sugiyama | SRRT ARS2 ASR2 | EEEAQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKF |
| Q9BXP5 | T705 | Sugiyama | SRRT ARS2 ASR2 | AQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKFKGP |
| Q9BYX7 | S365 | Sugiyama | POTEKP ACTBL3 FKSG30 | ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________ |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | T249 | Sugiyama | POTEKP ACTBL3 FKSG30 | MAASSSSVEKsyELPDGQVItIGNERFRCPEALFQPCFLGM |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9C0C2 | S1046 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | GLFsPstAHVPDGALGQRDQssWQNsDAsQEVGGHQERQQA |
| Q9C0C2 | S1631 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | TEPRAsRVPssDEEVVEEPQsRRTRMsLGTKGLKVNLFPGL |
| Q9H0B6 | S374 | Sugiyama | KLC2 | YATRLGPDDPNVAKTKNNLAsCyLKQGKYQDAETLYKEILT |
| Q9H2G2 | T1161 | Sugiyama | SLK KIAA0204 STK2 | NVRELHQLQNEKCHLLVEHEtQKLKELDEEHSQELKEWREK |
| Q9H3N1 | S92 | Sugiyama | TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 | WGEDLEVNIAKVDVTEQPGLsGRFIITALPTIYHCKDGEFR |
| Q9H788 | T142 | Sugiyama | SH2D4A PPP1R38 SH2A | TNsLKTKsQyHDLQAPDNQQtKDIWKKVAEKEELEQGsRPA |
| Q9NQ29 | S181 | Sugiyama | LUC7L LUC7L1 | KVRAKKKEAEEEYRNSMPASsFQQQKLRVCEVCSAYLGLHD |
| Q9NR30 | S466 | Sugiyama | DDX21 | ETKKEAQELSQNsAIKQDAQsLHGDIPQKQREITLKGFRNG |
| Q9NR45 | S251 | Sugiyama | NANS SAS | GAKVLERHITLDKTWKGsDHsAsLEPGELAELVRSVRLVER |
| Q9NSB2 | S178 | Sugiyama | KRT84 KRTHB4 | AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS |
| Q9NSK0 | S387 | Sugiyama | KLC4 KNSL8 | YEGQLGPDNPNVARTKNNLAsCyLKQGKYAEAETLYKEILT |
| Q9NZL9 | S16 | Sugiyama | MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 | _____MVGREKELsIHFVPGsCRLVEEEVNIPNRRVLVtGA |
| Q9NZL9 | S9 | Sugiyama | MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995 | ____________MVGREKELsIHFVPGsCRLVEEEVNIPNR |
| Q9NZZ3 | S86 | Sugiyama | CHMP5 C9orf83 SNF7DC2 CGI-34 HSPC177 PNAS-114 PNAS-2 | LRVLKQKRMYEQQRDNLAQQsFNMEQANytIQsLKDTKTTV |
| Q9NZZ3 | T95 | Sugiyama | CHMP5 C9orf83 SNF7DC2 CGI-34 HSPC177 PNAS-114 PNAS-2 | YEQQRDNLAQQsFNMEQANytIQsLKDTKTTVDAMKLGVKE |
| Q9UG63 | T617 | Sugiyama | ABCF2 HUSSY-18 | DILAYKEHLKSKLVDEEPQLtKRTHNV______________ |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UI15 | T190 | Sugiyama | TAGLN3 NP25 | GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________ |
| Q9UII2 | S39 | Sugiyama | ATP5IF1 ATPI ATPIF1 | TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF |
| Q9ULV4 | S389 | Sugiyama | CORO1C CRN2 CRNN4 | EAALEAEEWFEGKNADPILIsLKHGYIPGKNRDLKVVKKNI |
| Q9UMX5 | T130 | Sugiyama | NENF CIR2 SPUF | LTHDTTGLTAKELEALDEVFtKVYKAKYPIVGYTARRILNE |
| Q9UNX3 | T8 | Sugiyama | RPL26L1 RPL26P1 | _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK |
| Q9UNZ2 | S176 | Sugiyama | NSFL1C UBXN2C | RLGAAPEEEsAyVAGEKRQHssQDVHVVLKLWKsGFsLDNG |
| Q9UPQ0 | S201 | Sugiyama | LIMCH1 KIAA1102 | DCWDsERsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVV |
| Q9UPQ0 | S207 | Sugiyama | LIMCH1 KIAA1102 | RsDsLsPPRHGRDDsFDsLDsFGsRsRQtPsPDVVLRGssD |
| Q9UQ35 | S1648 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | APRALPRRSRSGSSSKGRGPsPEGssstEssPEHPPKSRTA |
| Q9UQ35 | S295 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | SRSRSRSAAAKtHttALAGRsPsPAsGRRGEGDAPFsEPGt |
| Q9UQ35 | S297 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | SRSRSAAAKtHttALAGRsPsPAsGRRGEGDAPFsEPGtts |
| Q9Y237 | S72 | Sugiyama | PIN4 | MEAMEKLKSGMRFNEVAAQysEDKARQGGDLGWMTRGSMVG |
| Q9Y262 | S255 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | VDKSNINRQLEVytsGGDPEsVAGEyGRHSLYKMLGYFSLV |
| Q9Y262 | S414 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | YGDKMLRMQKGDPQVyEELFsysCPKFLSPVVPNYDNVHPN |
| Q9Y266 | S60 | Sugiyama | NUDC | tDFFIGGEEGMAEKLItQTFsHHNQLAQKTRREKRARQEAE |
| Q9Y266 | T266 | Sugiyama | NUDC | EKINKMEWWSRLVssDPEINtKKINPENsKLsDLDsEtRsM |
| Q9Y266 | T56 | Sugiyama | NUDC | LRRKtDFFIGGEEGMAEKLItQTFsHHNQLAQKTRREKRAR |
| Q9Y2B0 | S115 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF |
| Q9Y2B0 | S74 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | GsFRINPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGE |
| Q9Y2B0 | T100 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | ELLEEICDRMKEyGEQIDPstHRKNYVRVVGRNGEssELDL |
| Q9Y2B0 | T79 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | NPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGEQIDPs |
| Q9Y383 | S181 | Sugiyama | LUC7L2 CGI-59 CGI-74 | KARAKKREAEEVyRNsMPASsFQQQKLRVCEVCSAYLGLHD |
| Q9Y3F4 | S160 | Sugiyama | STRAP MAWD UNRIP | SGHTSGIKKALWCsEDKQILsADDKtVRLWDHATMtEVKsL |
| Q9Y3F4 | S228 | Sugiyama | STRAP MAWD UNRIP | FHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDFKLy |
| Q9Y3F4 | S260 | Sugiyama | STRAP MAWD UNRIP | AGGEDFKLyKyDyNsGEELEsyKGHFGPIHCVRFSPDGELy |
| Q9Y3F4 | T109 | Sugiyama | STRAP MAWD UNRIP | VSGDELMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDL |
| Q9Y3F4 | T165 | Sugiyama | STRAP MAWD UNRIP | GIKKALWCsEDKQILsADDKtVRLWDHATMtEVKsLNFNMS |
| Q9Y3F4 | T225 | Sugiyama | STRAP MAWD UNRIP | SIAFHSAVSLDPIKsFEAPAtINsAsLHPEKEFLVAGGEDF |
| Q9Y3U8 | S91 | Sugiyama | RPL36 | KFIKKRVGTHIRAKRKREELsNVLAAMRKAAAKKD______ |
| Q9Y5S9 | S56 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle | R-HSA-1640170 | 7.771561e-16 | 15.109 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 2.553513e-15 | 14.593 | 0 | 0 |
| M Phase | R-HSA-68886 | 7.079892e-13 | 12.150 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 6.023404e-12 | 11.220 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 5.389100e-11 | 10.268 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 6.504708e-11 | 10.187 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.104529e-10 | 9.957 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 1.087527e-10 | 9.964 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.045506e-10 | 9.981 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.174796e-10 | 9.930 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 4.823628e-10 | 9.317 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 6.480613e-10 | 9.188 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.118164e-09 | 8.951 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 7.717906e-09 | 8.113 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 9.786047e-09 | 8.009 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.346267e-08 | 7.871 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.403691e-08 | 7.853 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 3.008305e-07 | 6.522 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 3.669455e-07 | 6.435 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 4.016595e-07 | 6.396 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 8.159793e-07 | 6.088 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 8.592816e-07 | 6.066 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 1.019603e-06 | 5.992 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.398802e-06 | 5.854 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.595661e-06 | 5.797 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.595661e-06 | 5.797 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.770668e-06 | 5.752 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.840998e-06 | 5.735 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.142883e-06 | 5.669 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 2.412101e-06 | 5.618 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 2.412101e-06 | 5.618 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 2.326758e-06 | 5.633 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 2.833674e-06 | 5.548 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 3.743343e-06 | 5.427 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 3.882545e-06 | 5.411 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.586297e-06 | 5.339 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 4.916797e-06 | 5.308 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 5.067269e-06 | 5.295 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 5.398258e-06 | 5.268 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 6.641605e-06 | 5.178 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 6.914198e-06 | 5.160 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 8.843315e-06 | 5.053 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 9.443300e-06 | 5.025 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 1.185649e-05 | 4.926 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.235208e-05 | 4.908 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.328625e-05 | 4.877 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 2.265389e-05 | 4.645 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 2.757037e-05 | 4.560 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.927760e-05 | 4.533 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 3.322217e-05 | 4.479 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 3.674688e-05 | 4.435 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 4.126972e-05 | 4.384 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 4.917669e-05 | 4.308 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 4.816609e-05 | 4.317 | 0 | 0 |
| Kinesins | R-HSA-983189 | 4.917669e-05 | 4.308 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 5.132385e-05 | 4.290 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 6.083982e-05 | 4.216 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 6.529212e-05 | 4.185 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 7.608371e-05 | 4.119 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 7.666767e-05 | 4.115 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 8.680173e-05 | 4.061 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 8.803372e-05 | 4.055 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 9.302350e-05 | 4.031 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 9.523337e-05 | 4.021 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 9.737587e-05 | 4.012 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 1.010242e-04 | 3.996 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 1.183375e-04 | 3.927 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.197052e-04 | 3.922 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 1.213552e-04 | 3.916 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.271751e-04 | 3.896 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.277909e-04 | 3.894 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.597484e-04 | 3.797 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.656856e-04 | 3.781 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 1.656856e-04 | 3.781 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.691046e-04 | 3.772 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.835952e-04 | 3.736 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 2.187961e-04 | 3.660 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 2.213357e-04 | 3.655 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.657955e-04 | 3.575 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.860827e-04 | 3.544 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 3.384798e-04 | 3.470 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 3.458874e-04 | 3.461 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 3.478676e-04 | 3.459 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 3.717357e-04 | 3.430 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 3.604016e-04 | 3.443 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 3.944817e-04 | 3.404 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 4.415329e-04 | 3.355 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 4.415329e-04 | 3.355 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 4.556619e-04 | 3.341 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.330784e-04 | 3.273 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 5.561723e-04 | 3.255 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 5.919852e-04 | 3.228 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 6.054230e-04 | 3.218 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 6.185418e-04 | 3.209 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 6.626976e-04 | 3.179 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 6.699158e-04 | 3.174 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 6.876152e-04 | 3.163 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 6.876152e-04 | 3.163 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 7.642918e-04 | 3.117 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 8.900735e-04 | 3.051 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 8.900735e-04 | 3.051 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 8.900735e-04 | 3.051 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 8.456637e-04 | 3.073 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 8.525459e-04 | 3.069 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 9.474811e-04 | 3.023 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 1.015087e-03 | 2.993 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 9.590721e-04 | 3.018 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.015717e-03 | 2.993 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 1.015717e-03 | 2.993 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 9.608444e-04 | 3.017 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 9.590721e-04 | 3.018 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 1.027828e-03 | 2.988 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.051295e-03 | 2.978 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.167687e-03 | 2.933 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 1.190272e-03 | 2.924 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 1.224116e-03 | 2.912 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.280027e-03 | 2.893 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.347405e-03 | 2.871 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.447606e-03 | 2.839 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.453493e-03 | 2.838 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.466133e-03 | 2.834 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.546610e-03 | 2.811 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 1.672281e-03 | 2.777 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.727290e-03 | 2.763 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.727290e-03 | 2.763 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 1.820710e-03 | 2.740 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.826601e-03 | 2.738 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 1.832375e-03 | 2.737 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.995664e-03 | 2.700 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 2.079926e-03 | 2.682 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 2.091462e-03 | 2.680 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 2.116263e-03 | 2.674 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 2.189445e-03 | 2.660 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 2.200417e-03 | 2.657 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 2.294246e-03 | 2.639 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 2.349729e-03 | 2.629 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 2.428538e-03 | 2.615 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 2.489308e-03 | 2.604 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.602741e-03 | 2.585 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 2.655892e-03 | 2.576 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 2.908236e-03 | 2.536 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 2.908236e-03 | 2.536 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.972615e-03 | 2.527 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 3.071202e-03 | 2.513 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 3.189409e-03 | 2.496 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 3.195325e-03 | 2.495 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 3.300511e-03 | 2.481 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 3.394144e-03 | 2.469 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 3.394144e-03 | 2.469 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 3.566538e-03 | 2.448 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.587290e-03 | 2.445 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 3.808239e-03 | 2.419 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 4.082076e-03 | 2.389 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 4.196936e-03 | 2.377 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 4.250119e-03 | 2.372 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 3.950991e-03 | 2.403 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 3.959592e-03 | 2.402 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 3.887236e-03 | 2.410 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 3.930678e-03 | 2.406 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 4.360943e-03 | 2.360 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.360943e-03 | 2.360 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 4.583083e-03 | 2.339 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 4.606284e-03 | 2.337 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 4.633289e-03 | 2.334 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 4.848080e-03 | 2.314 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 4.848080e-03 | 2.314 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 5.036235e-03 | 2.298 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 5.083214e-03 | 2.294 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 5.603171e-03 | 2.252 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 5.783970e-03 | 2.238 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 5.783970e-03 | 2.238 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 5.622261e-03 | 2.250 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 5.622261e-03 | 2.250 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 5.622261e-03 | 2.250 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 5.272895e-03 | 2.278 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 5.272895e-03 | 2.278 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 5.398400e-03 | 2.268 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 5.406570e-03 | 2.267 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 5.820565e-03 | 2.235 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 6.064371e-03 | 2.217 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 6.154694e-03 | 2.211 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 6.154694e-03 | 2.211 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 6.605758e-03 | 2.180 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 6.719647e-03 | 2.173 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 6.719647e-03 | 2.173 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 7.090782e-03 | 2.149 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 7.283940e-03 | 2.138 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 7.283940e-03 | 2.138 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 8.103791e-03 | 2.091 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 8.332783e-03 | 2.079 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 8.456551e-03 | 2.073 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 8.583732e-03 | 2.066 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 8.632464e-03 | 2.064 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 8.632464e-03 | 2.064 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 8.655947e-03 | 2.063 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 8.756950e-03 | 2.058 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 9.109570e-03 | 2.041 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 9.368237e-03 | 2.028 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 9.774616e-03 | 2.010 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 9.852503e-03 | 2.006 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.915863e-03 | 2.050 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 9.852503e-03 | 2.006 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.015523e-02 | 1.993 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.015523e-02 | 1.993 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.015523e-02 | 1.993 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.015523e-02 | 1.993 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 1.016263e-02 | 1.993 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.017894e-02 | 1.992 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.017894e-02 | 1.992 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 1.040765e-02 | 1.983 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 1.040765e-02 | 1.983 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 1.040765e-02 | 1.983 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 1.040765e-02 | 1.983 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 1.049948e-02 | 1.979 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 1.049948e-02 | 1.979 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.051883e-02 | 1.978 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 1.091874e-02 | 1.962 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.094109e-02 | 1.961 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.157609e-02 | 1.936 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.176629e-02 | 1.929 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.310217e-02 | 1.883 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.310217e-02 | 1.883 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.294224e-02 | 1.888 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.294224e-02 | 1.888 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 1.361307e-02 | 1.866 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 1.193448e-02 | 1.923 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.287270e-02 | 1.890 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.357422e-02 | 1.867 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.301255e-02 | 1.886 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 1.267188e-02 | 1.897 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.361307e-02 | 1.866 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.294224e-02 | 1.888 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.366822e-02 | 1.864 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.366822e-02 | 1.864 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.366822e-02 | 1.864 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.379922e-02 | 1.860 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.480337e-02 | 1.830 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.576261e-02 | 1.802 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.576261e-02 | 1.802 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.608875e-02 | 1.793 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.648357e-02 | 1.783 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.661954e-02 | 1.779 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.731845e-02 | 1.761 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 1.816282e-02 | 1.741 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.894698e-02 | 1.722 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.894698e-02 | 1.722 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.894698e-02 | 1.722 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.894698e-02 | 1.722 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.988805e-02 | 1.701 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 1.839334e-02 | 1.735 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 2.077057e-02 | 1.683 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.901531e-02 | 1.721 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.901531e-02 | 1.721 | 0 | 0 |
| Protein folding | R-HSA-391251 | 1.854192e-02 | 1.732 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 2.077057e-02 | 1.683 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 1.839334e-02 | 1.735 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 2.016486e-02 | 1.695 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.847803e-02 | 1.733 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.935334e-02 | 1.713 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 1.863335e-02 | 1.730 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 2.140342e-02 | 1.670 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 2.258006e-02 | 1.646 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.273478e-02 | 1.643 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.273478e-02 | 1.643 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 2.283682e-02 | 1.641 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 2.308011e-02 | 1.637 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.346148e-02 | 1.630 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 2.404361e-02 | 1.619 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 2.447156e-02 | 1.611 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.540306e-02 | 1.595 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 2.560771e-02 | 1.592 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 2.560771e-02 | 1.592 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 2.593763e-02 | 1.586 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.593763e-02 | 1.586 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 2.593763e-02 | 1.586 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 2.593763e-02 | 1.586 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 2.593763e-02 | 1.586 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 2.593763e-02 | 1.586 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.655250e-02 | 1.576 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 2.655250e-02 | 1.576 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.655250e-02 | 1.576 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.751181e-02 | 1.560 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 2.751181e-02 | 1.560 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 2.751181e-02 | 1.560 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.760640e-02 | 1.559 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.914869e-02 | 1.535 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 2.941653e-02 | 1.531 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 2.941653e-02 | 1.531 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 3.213079e-02 | 1.493 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 3.213079e-02 | 1.493 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 3.213079e-02 | 1.493 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 3.213079e-02 | 1.493 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 3.213079e-02 | 1.493 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 3.213079e-02 | 1.493 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 3.213079e-02 | 1.493 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 3.213079e-02 | 1.493 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.346241e-02 | 1.475 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 3.346241e-02 | 1.475 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 3.332905e-02 | 1.477 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.117901e-02 | 1.506 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.117901e-02 | 1.506 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 3.019689e-02 | 1.520 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 3.463078e-02 | 1.461 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 3.463078e-02 | 1.461 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.463078e-02 | 1.461 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 3.563371e-02 | 1.448 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 3.567714e-02 | 1.448 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 3.010950e-02 | 1.521 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 3.546983e-02 | 1.450 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 3.114244e-02 | 1.507 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 3.677294e-02 | 1.434 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 3.677294e-02 | 1.434 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 3.701370e-02 | 1.432 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 3.752719e-02 | 1.426 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 3.824804e-02 | 1.417 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 3.824804e-02 | 1.417 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 3.946990e-02 | 1.404 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.950871e-02 | 1.403 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 3.950871e-02 | 1.403 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 4.131711e-02 | 1.384 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 4.196291e-02 | 1.377 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 4.196291e-02 | 1.377 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 4.411891e-02 | 1.355 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.411891e-02 | 1.355 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 4.436812e-02 | 1.353 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 4.484610e-02 | 1.348 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 4.486352e-02 | 1.348 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 4.667626e-02 | 1.331 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 4.773860e-02 | 1.321 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 4.773860e-02 | 1.321 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 4.773880e-02 | 1.321 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 4.837026e-02 | 1.315 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 5.005712e-02 | 1.301 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 5.023598e-02 | 1.299 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 5.232820e-02 | 1.281 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 5.232820e-02 | 1.281 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 5.232820e-02 | 1.281 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 5.232820e-02 | 1.281 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 5.232820e-02 | 1.281 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 5.232820e-02 | 1.281 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 5.245706e-02 | 1.280 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 5.245706e-02 | 1.280 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 5.245706e-02 | 1.280 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 5.245706e-02 | 1.280 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 5.245706e-02 | 1.280 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 6.044043e-02 | 1.219 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 6.044043e-02 | 1.219 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 6.044043e-02 | 1.219 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 6.044043e-02 | 1.219 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 5.188468e-02 | 1.285 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 5.188468e-02 | 1.285 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 5.188468e-02 | 1.285 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 6.312107e-02 | 1.200 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 6.156412e-02 | 1.211 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 5.961309e-02 | 1.225 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 5.961309e-02 | 1.225 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 5.698074e-02 | 1.244 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 6.062582e-02 | 1.217 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 5.323179e-02 | 1.274 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 6.132551e-02 | 1.212 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 6.044043e-02 | 1.219 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 5.618059e-02 | 1.250 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 5.618059e-02 | 1.250 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 5.684402e-02 | 1.245 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 5.684402e-02 | 1.245 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 5.684402e-02 | 1.245 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 5.972478e-02 | 1.224 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 6.058752e-02 | 1.218 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 5.311368e-02 | 1.275 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 6.044043e-02 | 1.219 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 5.245216e-02 | 1.280 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 5.926061e-02 | 1.227 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 6.062582e-02 | 1.217 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 5.344575e-02 | 1.272 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 5.245706e-02 | 1.280 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 5.188468e-02 | 1.285 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 6.379542e-02 | 1.195 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 6.431686e-02 | 1.192 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 6.431686e-02 | 1.192 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 6.431686e-02 | 1.192 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 6.604811e-02 | 1.180 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 6.608501e-02 | 1.180 | 0 | 0 |
| Transport of glycerol from adipocytes to the liver by Aquaporins | R-HSA-432030 | 6.608501e-02 | 1.180 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 6.608501e-02 | 1.180 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 6.608501e-02 | 1.180 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 6.608501e-02 | 1.180 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 6.611682e-02 | 1.180 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 6.707107e-02 | 1.173 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 6.808908e-02 | 1.167 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 6.819051e-02 | 1.166 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 6.819051e-02 | 1.166 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 6.874465e-02 | 1.163 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 6.874465e-02 | 1.163 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 6.915385e-02 | 1.160 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 6.915385e-02 | 1.160 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 6.915385e-02 | 1.160 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 6.915385e-02 | 1.160 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 6.915385e-02 | 1.160 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 6.915385e-02 | 1.160 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 6.915385e-02 | 1.160 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 7.042483e-02 | 1.152 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 7.113289e-02 | 1.148 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 7.113289e-02 | 1.148 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 7.113289e-02 | 1.148 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 7.131506e-02 | 1.147 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 7.144047e-02 | 1.146 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 7.274537e-02 | 1.138 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 7.322068e-02 | 1.135 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 7.409749e-02 | 1.130 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 7.409749e-02 | 1.130 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.487584e-02 | 1.126 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 7.487584e-02 | 1.126 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 7.487584e-02 | 1.126 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 7.487584e-02 | 1.126 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 7.487584e-02 | 1.126 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 7.487584e-02 | 1.126 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 7.487584e-02 | 1.126 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 7.526033e-02 | 1.123 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 7.526033e-02 | 1.123 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 7.526033e-02 | 1.123 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 7.526033e-02 | 1.123 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 7.526033e-02 | 1.123 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 7.526033e-02 | 1.123 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 7.607855e-02 | 1.119 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 7.623372e-02 | 1.118 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 7.724651e-02 | 1.112 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 7.735559e-02 | 1.112 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 7.738268e-02 | 1.111 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 7.792258e-02 | 1.108 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 7.898997e-02 | 1.102 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 1.018343e-01 | 0.992 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 1.018343e-01 | 0.992 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 1.018343e-01 | 0.992 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 8.824600e-02 | 1.054 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 8.824600e-02 | 1.054 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 8.955085e-02 | 1.048 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 1.047059e-01 | 0.980 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 8.618309e-02 | 1.065 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 8.195344e-02 | 1.086 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 9.932116e-02 | 1.003 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 9.347836e-02 | 1.029 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 8.758287e-02 | 1.058 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 1.058811e-01 | 0.975 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 8.183590e-02 | 1.087 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 9.159167e-02 | 1.038 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 8.895527e-02 | 1.051 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 9.748590e-02 | 1.011 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 8.996709e-02 | 1.046 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 9.072865e-02 | 1.042 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 8.091368e-02 | 1.092 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 1.028405e-01 | 0.988 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 9.071911e-02 | 1.042 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 1.028405e-01 | 0.988 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 8.507163e-02 | 1.070 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 8.195344e-02 | 1.086 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.061366e-01 | 0.974 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 9.347836e-02 | 1.029 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 9.824436e-02 | 1.008 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.018343e-01 | 0.992 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 8.742993e-02 | 1.058 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.047059e-01 | 0.980 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 1.067472e-01 | 0.972 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 8.090597e-02 | 1.092 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 9.222257e-02 | 1.035 | 0 | 0 |
| S Phase | R-HSA-69242 | 9.258569e-02 | 1.033 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 8.955085e-02 | 1.048 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.955085e-02 | 1.048 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.195344e-02 | 1.086 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 8.507163e-02 | 1.070 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 8.183590e-02 | 1.087 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 1.047059e-01 | 0.980 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 8.924883e-02 | 1.049 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 9.854272e-02 | 1.006 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 9.629094e-02 | 1.016 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 8.824600e-02 | 1.054 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 8.742993e-02 | 1.058 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 9.514121e-02 | 1.022 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 9.514121e-02 | 1.022 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 8.824600e-02 | 1.054 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 9.824436e-02 | 1.008 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 9.854272e-02 | 1.006 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.030354e-01 | 0.987 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 1.075145e-01 | 0.969 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 1.075145e-01 | 0.969 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 1.075145e-01 | 0.969 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 1.075145e-01 | 0.969 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 1.075145e-01 | 0.969 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.087804e-01 | 0.963 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 1.087804e-01 | 0.963 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.087804e-01 | 0.963 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.095863e-01 | 0.960 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 1.095863e-01 | 0.960 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 1.095863e-01 | 0.960 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.095863e-01 | 0.960 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 1.095863e-01 | 0.960 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.102553e-01 | 0.958 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 1.106917e-01 | 0.956 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 1.110365e-01 | 0.955 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.130904e-01 | 0.947 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.131725e-01 | 0.946 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 1.134904e-01 | 0.945 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 1.142228e-01 | 0.942 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.142228e-01 | 0.942 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 1.148118e-01 | 0.940 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.159893e-01 | 0.936 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 1.159893e-01 | 0.936 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.159893e-01 | 0.936 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 1.183703e-01 | 0.927 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 1.191455e-01 | 0.924 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.191455e-01 | 0.924 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 1.199545e-01 | 0.921 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.199545e-01 | 0.921 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 1.227082e-01 | 0.911 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 1.227082e-01 | 0.911 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 1.230478e-01 | 0.910 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.230478e-01 | 0.910 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 1.248184e-01 | 0.904 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 1.252168e-01 | 0.902 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.262832e-01 | 0.899 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 1.272421e-01 | 0.895 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 1.280978e-01 | 0.892 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 1.280978e-01 | 0.892 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 1.280978e-01 | 0.892 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 1.280978e-01 | 0.892 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.280978e-01 | 0.892 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 1.286591e-01 | 0.891 | 0 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 1.297046e-01 | 0.887 | 0 | 0 |
| Drug resistance of PDGFR mutants | R-HSA-9674415 | 1.297046e-01 | 0.887 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 1.297046e-01 | 0.887 | 0 | 0 |
| PDGFR mutants bind TKIs | R-HSA-9674428 | 1.297046e-01 | 0.887 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.297046e-01 | 0.887 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 1.297046e-01 | 0.887 | 0 | 0 |
| Sunitinib-resistant PDGFR mutants | R-HSA-9674401 | 1.297046e-01 | 0.887 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 1.297046e-01 | 0.887 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.297046e-01 | 0.887 | 0 | 0 |
| Sorafenib-resistant PDGFR mutants | R-HSA-9674404 | 1.297046e-01 | 0.887 | 0 | 0 |
| Regorafenib-resistant PDGFR mutants | R-HSA-9674403 | 1.297046e-01 | 0.887 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 1.297046e-01 | 0.887 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 1.297046e-01 | 0.887 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 1.297046e-01 | 0.887 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.297046e-01 | 0.887 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.297046e-01 | 0.887 | 0 | 0 |
| Imatinib-resistant PDGFR mutants | R-HSA-9674396 | 1.297046e-01 | 0.887 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 1.297046e-01 | 0.887 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 1.297046e-01 | 0.887 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 1.297046e-01 | 0.887 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 1.297046e-01 | 0.887 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 1.539105e-01 | 0.813 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of other transcription factors | R-HSA-8866906 | 1.539105e-01 | 0.813 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 1.539105e-01 | 0.813 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.539105e-01 | 0.813 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 1.539105e-01 | 0.813 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 1.539105e-01 | 0.813 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 1.638484e-01 | 0.786 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 1.638484e-01 | 0.786 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 1.638484e-01 | 0.786 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 1.638484e-01 | 0.786 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 1.638484e-01 | 0.786 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.638484e-01 | 0.786 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 1.638484e-01 | 0.786 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 1.638484e-01 | 0.786 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.329850e-01 | 0.876 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.329850e-01 | 0.876 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.329850e-01 | 0.876 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.329850e-01 | 0.876 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.329850e-01 | 0.876 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.582207e-01 | 0.801 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.582207e-01 | 0.801 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 1.488530e-01 | 0.827 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 1.850512e-01 | 0.733 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 1.850512e-01 | 0.733 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.850512e-01 | 0.733 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 1.850512e-01 | 0.733 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 1.709191e-01 | 0.767 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 1.709191e-01 | 0.767 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 1.573648e-01 | 0.803 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 1.941566e-01 | 0.712 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.941566e-01 | 0.712 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 1.447861e-01 | 0.839 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.332481e-01 | 0.875 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 1.770798e-01 | 0.752 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.770798e-01 | 0.752 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 1.770798e-01 | 0.752 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 1.770798e-01 | 0.752 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 1.770798e-01 | 0.752 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.618216e-01 | 0.791 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 1.497591e-01 | 0.825 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.375374e-01 | 0.862 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 1.637428e-01 | 0.786 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.363905e-01 | 0.865 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 1.363905e-01 | 0.865 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.368771e-01 | 0.864 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 1.753740e-01 | 0.756 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 1.518408e-01 | 0.819 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 1.417324e-01 | 0.849 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 1.674584e-01 | 0.776 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 1.497591e-01 | 0.825 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 1.899971e-01 | 0.721 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.576709e-01 | 0.802 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 1.386778e-01 | 0.858 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 1.802524e-01 | 0.744 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 1.850512e-01 | 0.733 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 1.709191e-01 | 0.767 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 1.337332e-01 | 0.874 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 1.644017e-01 | 0.784 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.802524e-01 | 0.744 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 1.488530e-01 | 0.827 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 1.638408e-01 | 0.786 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 1.358838e-01 | 0.867 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 1.686497e-01 | 0.773 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 1.447861e-01 | 0.839 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 1.419452e-01 | 0.848 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 1.329850e-01 | 0.876 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.409465e-01 | 0.851 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 1.770798e-01 | 0.752 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.447861e-01 | 0.839 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 1.887052e-01 | 0.724 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.802524e-01 | 0.744 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.852943e-01 | 0.732 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.675207e-01 | 0.776 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.311534e-01 | 0.882 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.375374e-01 | 0.862 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.591182e-01 | 0.798 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.582207e-01 | 0.801 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.582207e-01 | 0.801 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 1.802524e-01 | 0.744 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.790135e-01 | 0.747 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 1.539105e-01 | 0.813 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 1.638484e-01 | 0.786 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 1.757328e-01 | 0.755 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 1.793031e-01 | 0.746 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 1.607235e-01 | 0.794 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.802401e-01 | 0.744 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 1.794949e-01 | 0.746 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.540231e-01 | 0.812 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 1.943006e-01 | 0.712 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.952876e-01 | 0.709 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 1.952876e-01 | 0.709 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.425924e-01 | 0.615 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.425924e-01 | 0.615 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 2.425924e-01 | 0.615 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 2.425924e-01 | 0.615 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 2.425924e-01 | 0.615 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 2.425924e-01 | 0.615 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 2.425924e-01 | 0.615 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 2.425924e-01 | 0.615 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 2.032891e-01 | 0.692 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 2.032891e-01 | 0.692 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 2.032891e-01 | 0.692 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 2.032891e-01 | 0.692 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 2.032891e-01 | 0.692 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 2.032891e-01 | 0.692 | 0 | 0 |
| Abasic sugar-phosphate removal via the single-nucleotide replacement pathway | R-HSA-73930 | 3.408430e-01 | 0.467 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 3.408430e-01 | 0.467 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 3.408430e-01 | 0.467 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 3.408430e-01 | 0.467 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 3.408430e-01 | 0.467 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 3.408430e-01 | 0.467 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 3.408430e-01 | 0.467 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.408430e-01 | 0.467 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 3.408430e-01 | 0.467 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5619081 | 3.408430e-01 | 0.467 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5660724 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 3.408430e-01 | 0.467 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.408430e-01 | 0.467 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 3.408430e-01 | 0.467 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 3.408430e-01 | 0.467 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 3.408430e-01 | 0.467 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 3.408430e-01 | 0.467 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 3.408430e-01 | 0.467 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 3.408430e-01 | 0.467 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 3.408430e-01 | 0.467 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.408430e-01 | 0.467 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.408430e-01 | 0.467 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.540969e-01 | 0.595 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 2.540969e-01 | 0.595 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 2.540969e-01 | 0.595 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 1.981984e-01 | 0.703 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 2.340642e-01 | 0.631 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 3.051329e-01 | 0.516 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 3.051329e-01 | 0.516 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 3.051329e-01 | 0.516 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 3.051329e-01 | 0.516 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 2.132226e-01 | 0.671 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.132226e-01 | 0.671 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 2.709482e-01 | 0.567 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 2.709482e-01 | 0.567 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 2.709482e-01 | 0.567 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 2.424770e-01 | 0.615 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 3.554838e-01 | 0.449 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 3.554838e-01 | 0.449 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 3.554838e-01 | 0.449 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 3.554838e-01 | 0.449 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 3.554838e-01 | 0.449 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 2.184163e-01 | 0.661 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 2.184163e-01 | 0.661 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.184163e-01 | 0.661 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 2.184163e-01 | 0.661 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 1.977316e-01 | 0.704 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 3.083948e-01 | 0.511 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.725592e-01 | 0.565 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 2.725592e-01 | 0.565 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 2.435438e-01 | 0.613 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 1.983817e-01 | 0.702 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 1.973463e-01 | 0.705 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 2.177727e-01 | 0.662 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 2.177727e-01 | 0.662 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 2.177727e-01 | 0.662 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 2.177727e-01 | 0.662 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.414475e-01 | 0.617 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 2.414475e-01 | 0.617 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 2.693817e-01 | 0.570 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 2.693817e-01 | 0.570 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 2.693817e-01 | 0.570 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 2.693817e-01 | 0.570 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 3.032222e-01 | 0.518 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 3.459961e-01 | 0.461 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 3.459961e-01 | 0.461 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 3.459961e-01 | 0.461 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 3.459961e-01 | 0.461 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 2.378073e-01 | 0.624 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 2.378073e-01 | 0.624 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 2.957734e-01 | 0.529 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 2.957734e-01 | 0.529 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 3.342310e-01 | 0.476 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 2.584084e-01 | 0.588 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 3.833939e-01 | 0.416 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 3.833939e-01 | 0.416 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 3.833939e-01 | 0.416 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 3.833939e-01 | 0.416 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 2.132705e-01 | 0.671 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 2.714645e-01 | 0.566 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 3.114603e-01 | 0.507 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 3.114603e-01 | 0.507 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 3.653658e-01 | 0.437 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 2.334572e-01 | 0.632 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 2.334572e-01 | 0.632 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 2.636722e-01 | 0.579 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 2.636722e-01 | 0.579 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 2.158971e-01 | 0.666 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 2.158971e-01 | 0.666 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 3.355496e-01 | 0.474 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 3.355496e-01 | 0.474 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.352954e-01 | 0.628 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.228120e-01 | 0.491 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 3.767609e-01 | 0.424 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 3.767609e-01 | 0.424 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 3.767609e-01 | 0.424 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 3.448779e-01 | 0.462 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 3.448779e-01 | 0.462 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 3.448779e-01 | 0.462 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 3.314095e-01 | 0.480 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.342317e-01 | 0.630 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 2.276968e-01 | 0.643 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 3.191244e-01 | 0.496 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 3.191244e-01 | 0.496 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.462093e-01 | 0.609 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 3.381352e-01 | 0.471 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 3.671103e-01 | 0.435 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 3.671103e-01 | 0.435 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 3.435241e-01 | 0.464 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 3.616395e-01 | 0.442 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 3.026161e-01 | 0.519 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 2.559005e-01 | 0.592 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 3.546088e-01 | 0.450 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 3.824334e-01 | 0.417 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 2.547692e-01 | 0.594 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 2.051458e-01 | 0.688 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 3.573241e-01 | 0.447 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 3.009915e-01 | 0.521 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 2.709482e-01 | 0.567 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 2.693817e-01 | 0.570 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 3.093660e-01 | 0.510 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 3.421739e-01 | 0.466 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 3.312269e-01 | 0.480 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 2.730608e-01 | 0.564 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 3.023102e-01 | 0.520 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.968932e-01 | 0.706 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 2.082187e-01 | 0.681 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.779038e-01 | 0.556 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.810094e-01 | 0.551 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 3.842247e-01 | 0.415 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 1.994915e-01 | 0.700 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 2.227042e-01 | 0.652 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.096740e-01 | 0.678 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 3.003429e-01 | 0.522 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 3.003429e-01 | 0.522 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 2.837122e-01 | 0.547 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 3.026161e-01 | 0.519 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 3.894874e-01 | 0.410 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.709482e-01 | 0.567 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 1.977316e-01 | 0.704 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 3.032222e-01 | 0.518 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 2.116454e-01 | 0.674 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 3.225652e-01 | 0.491 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 2.794967e-01 | 0.554 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 3.496083e-01 | 0.456 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 3.314095e-01 | 0.480 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.096740e-01 | 0.678 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 2.362673e-01 | 0.627 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 3.902041e-01 | 0.409 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 2.215835e-01 | 0.654 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 2.588299e-01 | 0.587 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 3.920117e-01 | 0.407 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 3.314095e-01 | 0.480 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 3.314095e-01 | 0.480 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 2.319725e-01 | 0.635 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 3.114603e-01 | 0.507 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 3.448779e-01 | 0.462 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 2.588299e-01 | 0.587 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 2.051458e-01 | 0.688 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 3.554838e-01 | 0.449 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 3.554838e-01 | 0.449 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.977316e-01 | 0.704 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 2.725592e-01 | 0.565 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 3.355496e-01 | 0.474 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 3.767609e-01 | 0.424 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 3.078079e-01 | 0.512 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 1.977316e-01 | 0.704 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 2.306250e-01 | 0.637 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 2.757948e-01 | 0.559 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 2.636722e-01 | 0.579 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 2.150710e-01 | 0.667 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 2.957734e-01 | 0.529 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 2.032485e-01 | 0.692 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 2.116454e-01 | 0.674 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 3.804256e-01 | 0.420 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 3.381352e-01 | 0.471 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 2.827590e-01 | 0.549 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 2.614925e-01 | 0.583 | 0 | 0 |
| Activation and oligomerization of BAK protein | R-HSA-111452 | 2.425924e-01 | 0.615 | 0 | 0 |
| Inositol transporters | R-HSA-429593 | 2.540969e-01 | 0.595 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 3.051329e-01 | 0.516 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 3.051329e-01 | 0.516 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 2.184163e-01 | 0.661 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 3.032222e-01 | 0.518 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 3.032222e-01 | 0.518 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 3.459961e-01 | 0.461 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 2.557520e-01 | 0.592 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 3.842247e-01 | 0.415 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 3.679775e-01 | 0.434 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.236119e-01 | 0.651 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 3.098526e-01 | 0.509 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 3.342310e-01 | 0.476 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 3.833939e-01 | 0.416 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 2.874932e-01 | 0.541 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 3.894323e-01 | 0.410 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 3.676569e-01 | 0.435 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 3.546088e-01 | 0.450 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 2.647432e-01 | 0.577 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 2.340642e-01 | 0.631 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 3.093660e-01 | 0.510 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 3.191244e-01 | 0.496 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.421739e-01 | 0.466 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 2.540969e-01 | 0.595 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 3.518875e-01 | 0.454 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 3.225652e-01 | 0.491 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.653658e-01 | 0.437 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 2.150349e-01 | 0.667 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 3.671103e-01 | 0.435 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 2.769062e-01 | 0.558 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.425924e-01 | 0.615 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 2.425924e-01 | 0.615 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 2.540969e-01 | 0.595 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 2.340642e-01 | 0.631 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 3.083948e-01 | 0.511 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 3.083948e-01 | 0.511 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 3.833939e-01 | 0.416 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 3.448779e-01 | 0.462 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 3.311619e-01 | 0.480 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 3.515617e-01 | 0.454 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 2.720290e-01 | 0.565 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 3.114603e-01 | 0.507 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 3.123060e-01 | 0.505 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 3.003429e-01 | 0.522 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 2.521893e-01 | 0.598 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 2.808812e-01 | 0.551 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 3.355496e-01 | 0.474 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.693817e-01 | 0.570 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 3.163477e-01 | 0.500 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 3.083948e-01 | 0.511 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 3.009915e-01 | 0.521 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 2.340642e-01 | 0.631 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 3.083948e-01 | 0.511 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.435438e-01 | 0.613 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 3.342310e-01 | 0.476 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.144690e-01 | 0.669 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 2.192220e-01 | 0.659 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 2.082187e-01 | 0.681 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 2.184163e-01 | 0.661 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 3.894323e-01 | 0.410 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 2.540969e-01 | 0.595 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.340642e-01 | 0.631 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 2.340642e-01 | 0.631 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 3.051329e-01 | 0.516 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 3.051329e-01 | 0.516 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 2.709482e-01 | 0.567 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 2.424770e-01 | 0.615 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 3.554838e-01 | 0.449 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 3.083948e-01 | 0.511 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 3.083948e-01 | 0.511 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 3.598382e-01 | 0.444 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 3.894323e-01 | 0.410 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 3.665890e-01 | 0.436 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 2.184163e-01 | 0.661 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.521893e-01 | 0.598 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 2.720290e-01 | 0.565 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 2.353255e-01 | 0.628 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 2.957734e-01 | 0.529 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 3.051329e-01 | 0.516 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 3.833939e-01 | 0.416 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 3.671103e-01 | 0.435 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 3.902041e-01 | 0.409 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 2.435438e-01 | 0.613 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 2.138511e-01 | 0.670 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 2.032485e-01 | 0.692 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 2.340642e-01 | 0.631 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 3.051329e-01 | 0.516 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 3.051329e-01 | 0.516 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 3.342310e-01 | 0.476 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 3.225652e-01 | 0.491 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 3.654300e-01 | 0.437 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.725592e-01 | 0.565 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 3.026161e-01 | 0.519 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.264433e-01 | 0.645 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 3.003585e-01 | 0.522 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 2.634209e-01 | 0.579 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 2.404746e-01 | 0.619 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 3.964245e-01 | 0.402 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 3.964245e-01 | 0.402 | 0 | 0 |
| PKA activation | R-HSA-163615 | 3.964245e-01 | 0.402 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 3.964245e-01 | 0.402 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 3.964245e-01 | 0.402 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 3.981739e-01 | 0.400 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 3.981739e-01 | 0.400 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 3.981739e-01 | 0.400 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 4.002492e-01 | 0.398 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 4.010702e-01 | 0.397 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 4.031583e-01 | 0.395 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 4.033119e-01 | 0.394 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 4.038890e-01 | 0.394 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 4.044687e-01 | 0.393 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 4.044687e-01 | 0.393 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 4.044687e-01 | 0.393 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 4.044687e-01 | 0.393 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 4.044687e-01 | 0.393 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 4.086125e-01 | 0.389 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 4.086125e-01 | 0.389 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 4.111868e-01 | 0.386 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 4.131766e-01 | 0.384 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 4.161110e-01 | 0.381 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 4.177795e-01 | 0.379 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 4.179607e-01 | 0.379 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 4.179607e-01 | 0.379 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 4.202800e-01 | 0.376 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 4.202800e-01 | 0.376 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 4.202800e-01 | 0.376 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 4.202800e-01 | 0.376 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 4.202800e-01 | 0.376 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 4.202800e-01 | 0.376 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 4.202800e-01 | 0.376 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.202800e-01 | 0.376 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 4.202800e-01 | 0.376 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 4.263535e-01 | 0.370 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 4.263535e-01 | 0.370 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 4.263535e-01 | 0.370 | 0 | 0 |
| Interaction between PHLDA1 and AURKA | R-HSA-8854521 | 4.263535e-01 | 0.370 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 4.263535e-01 | 0.370 | 0 | 0 |
| Signaling by RAS GAP mutants | R-HSA-9753510 | 4.263535e-01 | 0.370 | 0 | 0 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 | R-HSA-5083633 | 4.263535e-01 | 0.370 | 0 | 0 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 | R-HSA-5083629 | 4.263535e-01 | 0.370 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 4.263535e-01 | 0.370 | 0 | 0 |
| Neurophilin interactions with VEGF and VEGFR | R-HSA-194306 | 4.263535e-01 | 0.370 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 4.263535e-01 | 0.370 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 4.272238e-01 | 0.369 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 4.272238e-01 | 0.369 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 4.272238e-01 | 0.369 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 4.274638e-01 | 0.369 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 4.274638e-01 | 0.369 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 4.274638e-01 | 0.369 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 4.308681e-01 | 0.366 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 4.308681e-01 | 0.366 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 4.308681e-01 | 0.366 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 4.308681e-01 | 0.366 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 4.316070e-01 | 0.365 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 4.340518e-01 | 0.362 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 4.340518e-01 | 0.362 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 4.346397e-01 | 0.362 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 4.348644e-01 | 0.362 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 4.475739e-01 | 0.349 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 4.475739e-01 | 0.349 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 4.515950e-01 | 0.345 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 4.515950e-01 | 0.345 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 4.515950e-01 | 0.345 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 4.515950e-01 | 0.345 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 4.515950e-01 | 0.345 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 4.515950e-01 | 0.345 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 4.515950e-01 | 0.345 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 4.515950e-01 | 0.345 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.515950e-01 | 0.345 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.542068e-01 | 0.343 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 4.542068e-01 | 0.343 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 4.552480e-01 | 0.342 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 4.563941e-01 | 0.341 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 4.563941e-01 | 0.341 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 4.563941e-01 | 0.341 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 4.570312e-01 | 0.340 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 4.570312e-01 | 0.340 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 4.570312e-01 | 0.340 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 4.575837e-01 | 0.340 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 4.576000e-01 | 0.340 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 4.576000e-01 | 0.340 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 4.576000e-01 | 0.340 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 4.576000e-01 | 0.340 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 4.607684e-01 | 0.337 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 4.614532e-01 | 0.336 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 4.623368e-01 | 0.335 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 4.656721e-01 | 0.332 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 4.734424e-01 | 0.325 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 4.734424e-01 | 0.325 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 4.757168e-01 | 0.323 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 4.757168e-01 | 0.323 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 4.757168e-01 | 0.323 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 4.781842e-01 | 0.320 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 4.781842e-01 | 0.320 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 4.781842e-01 | 0.320 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 4.808968e-01 | 0.318 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 4.808968e-01 | 0.318 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 4.824102e-01 | 0.317 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 4.825584e-01 | 0.316 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 4.839281e-01 | 0.315 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 4.839316e-01 | 0.315 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 4.839316e-01 | 0.315 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 4.839316e-01 | 0.315 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 4.839316e-01 | 0.315 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 4.874090e-01 | 0.312 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 4.874090e-01 | 0.312 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 4.874090e-01 | 0.312 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 4.874090e-01 | 0.312 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 4.894069e-01 | 0.310 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 4.894069e-01 | 0.310 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 4.899054e-01 | 0.310 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 4.915213e-01 | 0.308 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.915213e-01 | 0.308 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 4.915213e-01 | 0.308 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 4.915213e-01 | 0.308 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 4.915213e-01 | 0.308 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.915213e-01 | 0.308 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.915213e-01 | 0.308 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 4.915213e-01 | 0.308 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 4.915213e-01 | 0.308 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 4.959971e-01 | 0.305 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 4.965207e-01 | 0.304 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 4.965207e-01 | 0.304 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 4.965207e-01 | 0.304 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 4.965207e-01 | 0.304 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 4.965207e-01 | 0.304 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 4.965207e-01 | 0.304 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 4.965207e-01 | 0.304 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 4.965207e-01 | 0.304 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 4.999123e-01 | 0.301 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 4.999123e-01 | 0.301 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 5.002946e-01 | 0.301 | 0 | 0 |
| Adrenaline signalling through Alpha-2 adrenergic receptor | R-HSA-392023 | 5.007753e-01 | 0.300 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 5.007753e-01 | 0.300 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 5.007753e-01 | 0.300 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 5.007753e-01 | 0.300 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 5.007753e-01 | 0.300 | 0 | 0 |
| Adenosine P1 receptors | R-HSA-417973 | 5.007753e-01 | 0.300 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 5.007753e-01 | 0.300 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 5.007753e-01 | 0.300 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 5.007753e-01 | 0.300 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 5.007753e-01 | 0.300 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 5.007753e-01 | 0.300 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 5.036520e-01 | 0.298 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 5.044334e-01 | 0.297 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 5.044334e-01 | 0.297 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 5.044334e-01 | 0.297 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 5.098184e-01 | 0.293 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 5.114302e-01 | 0.291 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 5.140809e-01 | 0.289 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 5.165265e-01 | 0.287 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 5.189158e-01 | 0.285 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 5.213407e-01 | 0.283 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 5.213407e-01 | 0.283 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 5.213407e-01 | 0.283 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 5.213407e-01 | 0.283 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 5.213407e-01 | 0.283 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 5.243404e-01 | 0.280 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 5.254890e-01 | 0.279 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 5.254890e-01 | 0.279 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 5.254890e-01 | 0.279 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 5.254890e-01 | 0.279 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 5.254890e-01 | 0.279 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 5.254890e-01 | 0.279 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 5.254890e-01 | 0.279 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 5.275750e-01 | 0.278 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 5.283012e-01 | 0.277 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 5.301068e-01 | 0.276 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 5.326154e-01 | 0.274 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 5.351614e-01 | 0.272 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 5.351614e-01 | 0.272 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 5.351614e-01 | 0.272 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 5.351614e-01 | 0.272 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 5.373551e-01 | 0.270 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 5.390238e-01 | 0.268 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 5.390238e-01 | 0.268 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 5.390238e-01 | 0.268 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 5.390238e-01 | 0.268 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 5.390238e-01 | 0.268 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 5.390238e-01 | 0.268 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 5.390238e-01 | 0.268 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 5.424196e-01 | 0.266 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.426154e-01 | 0.266 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 5.436306e-01 | 0.265 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 5.448469e-01 | 0.264 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 5.448469e-01 | 0.264 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 5.456173e-01 | 0.263 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 5.485254e-01 | 0.261 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 5.502618e-01 | 0.259 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 5.539112e-01 | 0.257 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.539112e-01 | 0.257 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 5.572218e-01 | 0.254 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 5.581625e-01 | 0.253 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 5.581625e-01 | 0.253 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 5.598885e-01 | 0.252 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 5.598885e-01 | 0.252 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 5.599051e-01 | 0.252 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 5.631038e-01 | 0.249 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 5.631038e-01 | 0.249 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 5.638816e-01 | 0.249 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 5.655457e-01 | 0.248 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 5.655457e-01 | 0.248 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 5.655457e-01 | 0.248 | 0 | 0 |
| Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate | R-HSA-2978092 | 5.655457e-01 | 0.248 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 5.655457e-01 | 0.248 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 5.655457e-01 | 0.248 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.655457e-01 | 0.248 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 5.655457e-01 | 0.248 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 5.655457e-01 | 0.248 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.655457e-01 | 0.248 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 5.722826e-01 | 0.242 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 5.724412e-01 | 0.242 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 5.724412e-01 | 0.242 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 5.743694e-01 | 0.241 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 5.789766e-01 | 0.237 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 5.789766e-01 | 0.237 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 5.789766e-01 | 0.237 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 5.839380e-01 | 0.234 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 5.844658e-01 | 0.233 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 5.844658e-01 | 0.233 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 5.844658e-01 | 0.233 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 5.864832e-01 | 0.232 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 5.894413e-01 | 0.230 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 5.894413e-01 | 0.230 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 5.894413e-01 | 0.230 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 5.911915e-01 | 0.228 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 5.930885e-01 | 0.227 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 5.940670e-01 | 0.226 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 5.986873e-01 | 0.223 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 5.987630e-01 | 0.223 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 5.987630e-01 | 0.223 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 5.987630e-01 | 0.223 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 6.019324e-01 | 0.220 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 6.019324e-01 | 0.220 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.030548e-01 | 0.220 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 6.031308e-01 | 0.220 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 6.031308e-01 | 0.220 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 6.031308e-01 | 0.220 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 6.031308e-01 | 0.220 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 6.031308e-01 | 0.220 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 6.031308e-01 | 0.220 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 6.097448e-01 | 0.215 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 6.150997e-01 | 0.211 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 6.150997e-01 | 0.211 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 6.163254e-01 | 0.210 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 6.163254e-01 | 0.210 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 6.163254e-01 | 0.210 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 6.163254e-01 | 0.210 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 6.163254e-01 | 0.210 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 6.163254e-01 | 0.210 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 6.192552e-01 | 0.208 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 6.192552e-01 | 0.208 | 0 | 0 |
| Activation of AMPA receptors | R-HSA-399710 | 6.219160e-01 | 0.206 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 6.219160e-01 | 0.206 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 6.219160e-01 | 0.206 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 6.219160e-01 | 0.206 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 6.219160e-01 | 0.206 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 6.219160e-01 | 0.206 | 0 | 0 |
| Trafficking of myristoylated proteins to the cilium | R-HSA-5624138 | 6.219160e-01 | 0.206 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 6.219160e-01 | 0.206 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 6.219160e-01 | 0.206 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 6.219160e-01 | 0.206 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 6.219160e-01 | 0.206 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 6.219160e-01 | 0.206 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 6.219160e-01 | 0.206 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 6.219160e-01 | 0.206 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 6.242332e-01 | 0.205 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 6.242332e-01 | 0.205 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 6.298065e-01 | 0.201 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 6.355061e-01 | 0.197 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 6.357409e-01 | 0.197 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 6.357409e-01 | 0.197 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 6.379690e-01 | 0.195 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 6.418849e-01 | 0.193 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 6.418849e-01 | 0.193 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 6.428877e-01 | 0.192 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 6.466752e-01 | 0.189 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 6.475604e-01 | 0.189 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 6.475604e-01 | 0.189 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 6.475604e-01 | 0.189 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.475604e-01 | 0.189 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 6.475604e-01 | 0.189 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 6.475604e-01 | 0.189 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 6.475604e-01 | 0.189 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 6.475604e-01 | 0.189 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 6.475604e-01 | 0.189 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 6.475604e-01 | 0.189 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 6.475604e-01 | 0.189 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 6.486524e-01 | 0.188 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 6.486524e-01 | 0.188 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 6.486524e-01 | 0.188 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 6.510734e-01 | 0.186 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 6.510734e-01 | 0.186 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 6.510734e-01 | 0.186 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 6.510734e-01 | 0.186 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 6.510734e-01 | 0.186 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 6.510734e-01 | 0.186 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 6.510734e-01 | 0.186 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 6.510734e-01 | 0.186 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 6.515497e-01 | 0.186 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 6.515497e-01 | 0.186 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 6.520435e-01 | 0.186 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 6.549967e-01 | 0.184 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 6.552589e-01 | 0.184 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 6.552589e-01 | 0.184 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 6.553589e-01 | 0.184 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 6.570241e-01 | 0.182 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 6.572494e-01 | 0.182 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 6.572494e-01 | 0.182 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 6.679231e-01 | 0.175 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 6.709751e-01 | 0.173 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.709751e-01 | 0.173 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.709751e-01 | 0.173 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.709751e-01 | 0.173 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 6.709751e-01 | 0.173 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 6.709751e-01 | 0.173 | 0 | 0 |
| NGF-independant TRKA activation | R-HSA-187024 | 6.709751e-01 | 0.173 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 6.709751e-01 | 0.173 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 6.709751e-01 | 0.173 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 6.709751e-01 | 0.173 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.709751e-01 | 0.173 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.709751e-01 | 0.173 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.709751e-01 | 0.173 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.709751e-01 | 0.173 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.709751e-01 | 0.173 | 0 | 0 |
| VEGF binds to VEGFR leading to receptor dimerization | R-HSA-195399 | 6.709751e-01 | 0.173 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 6.709751e-01 | 0.173 | 0 | 0 |
| VEGF ligand-receptor interactions | R-HSA-194313 | 6.709751e-01 | 0.173 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 6.709751e-01 | 0.173 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 6.709751e-01 | 0.173 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 6.709751e-01 | 0.173 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 6.709751e-01 | 0.173 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 6.719932e-01 | 0.173 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 6.724627e-01 | 0.172 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 6.724627e-01 | 0.172 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 6.736063e-01 | 0.172 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 6.743357e-01 | 0.171 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 6.743357e-01 | 0.171 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 6.743357e-01 | 0.171 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 6.743357e-01 | 0.171 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 6.743365e-01 | 0.171 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 6.743365e-01 | 0.171 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 6.743365e-01 | 0.171 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 6.743365e-01 | 0.171 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 6.765152e-01 | 0.170 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 6.769742e-01 | 0.169 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 6.832666e-01 | 0.165 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 6.832666e-01 | 0.165 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 6.832666e-01 | 0.165 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 6.832666e-01 | 0.165 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 6.832666e-01 | 0.165 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 6.832666e-01 | 0.165 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 6.832666e-01 | 0.165 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 6.832666e-01 | 0.165 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 6.903581e-01 | 0.161 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 6.925278e-01 | 0.160 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 6.925278e-01 | 0.160 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 6.940156e-01 | 0.159 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 6.940156e-01 | 0.159 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 6.942396e-01 | 0.158 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 6.942396e-01 | 0.158 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 6.995793e-01 | 0.155 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 6.995793e-01 | 0.155 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 6.995793e-01 | 0.155 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 6.995793e-01 | 0.155 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 6.995793e-01 | 0.155 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 7.038482e-01 | 0.153 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 7.104063e-01 | 0.148 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 7.104063e-01 | 0.148 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 7.104623e-01 | 0.148 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 7.117348e-01 | 0.148 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 7.117348e-01 | 0.148 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 7.129022e-01 | 0.147 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 7.129829e-01 | 0.147 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 7.129829e-01 | 0.147 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 7.129829e-01 | 0.147 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 7.136709e-01 | 0.147 | 0 | 0 |
| Branched-chain ketoacid dehydrogenase kinase deficiency | R-HSA-9912481 | 7.136709e-01 | 0.147 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 7.136709e-01 | 0.147 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 7.136709e-01 | 0.147 | 0 | 0 |
| Defective CHST3 causes SEDCJD | R-HSA-3595172 | 7.136709e-01 | 0.147 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 7.136709e-01 | 0.147 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 7.136709e-01 | 0.147 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 7.136709e-01 | 0.147 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 7.136709e-01 | 0.147 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 7.136709e-01 | 0.147 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 7.136709e-01 | 0.147 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 7.136709e-01 | 0.147 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 7.136709e-01 | 0.147 | 0 | 0 |
| Leukotriene receptors | R-HSA-391906 | 7.136709e-01 | 0.147 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 7.136709e-01 | 0.147 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 7.136709e-01 | 0.147 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 7.153862e-01 | 0.145 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 7.262871e-01 | 0.139 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 7.262871e-01 | 0.139 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 7.262871e-01 | 0.139 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 7.262871e-01 | 0.139 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 7.262871e-01 | 0.139 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 7.263070e-01 | 0.139 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 7.263070e-01 | 0.139 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 7.263070e-01 | 0.139 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 7.273807e-01 | 0.138 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 7.273807e-01 | 0.138 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 7.281681e-01 | 0.138 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 7.296609e-01 | 0.137 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 7.297098e-01 | 0.137 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.300793e-01 | 0.137 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 7.334883e-01 | 0.135 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 7.334883e-01 | 0.135 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 7.354364e-01 | 0.133 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 7.368265e-01 | 0.133 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 7.403230e-01 | 0.131 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 7.403230e-01 | 0.131 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 7.403230e-01 | 0.131 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 7.403230e-01 | 0.131 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 7.406528e-01 | 0.130 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 7.406528e-01 | 0.130 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 7.430706e-01 | 0.129 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 7.436434e-01 | 0.129 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 7.455413e-01 | 0.128 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 7.455413e-01 | 0.128 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.455413e-01 | 0.128 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 7.455413e-01 | 0.128 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.455413e-01 | 0.128 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 7.455413e-01 | 0.128 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 7.483661e-01 | 0.126 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 7.508284e-01 | 0.124 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.508284e-01 | 0.124 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 7.508284e-01 | 0.124 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 7.508284e-01 | 0.124 | 0 | 0 |
| Defective CHSY1 causes TPBS | R-HSA-3595177 | 7.508284e-01 | 0.124 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 7.508284e-01 | 0.124 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.508284e-01 | 0.124 | 0 | 0 |
| Opsins | R-HSA-419771 | 7.508284e-01 | 0.124 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 7.508284e-01 | 0.124 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 7.508284e-01 | 0.124 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 7.508284e-01 | 0.124 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.508284e-01 | 0.124 | 0 | 0 |
| Activation of TRKA receptors | R-HSA-187015 | 7.508284e-01 | 0.124 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 7.508284e-01 | 0.124 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 7.508284e-01 | 0.124 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 7.508284e-01 | 0.124 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 7.508284e-01 | 0.124 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 7.521046e-01 | 0.124 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 7.544018e-01 | 0.122 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 7.544018e-01 | 0.122 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 7.591959e-01 | 0.120 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 7.591959e-01 | 0.120 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 7.619019e-01 | 0.118 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 7.641925e-01 | 0.117 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 7.654029e-01 | 0.116 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 7.654029e-01 | 0.116 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 7.654029e-01 | 0.116 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 7.654029e-01 | 0.116 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 7.654029e-01 | 0.116 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 7.654029e-01 | 0.116 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 7.657451e-01 | 0.116 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 7.702046e-01 | 0.113 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 7.723005e-01 | 0.112 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 7.723005e-01 | 0.112 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 7.723005e-01 | 0.112 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 7.723005e-01 | 0.112 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 7.723005e-01 | 0.112 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 7.774246e-01 | 0.109 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 7.776221e-01 | 0.109 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 7.799788e-01 | 0.108 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 7.831659e-01 | 0.106 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 7.831659e-01 | 0.106 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 7.831659e-01 | 0.106 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 7.831659e-01 | 0.106 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 7.831659e-01 | 0.106 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 7.831659e-01 | 0.106 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 7.831659e-01 | 0.106 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 7.831659e-01 | 0.106 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.831659e-01 | 0.106 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 7.831659e-01 | 0.106 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 7.831659e-01 | 0.106 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 7.831659e-01 | 0.106 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 7.831659e-01 | 0.106 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 7.831659e-01 | 0.106 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 7.831659e-01 | 0.106 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 7.836305e-01 | 0.106 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 7.857049e-01 | 0.105 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 7.857049e-01 | 0.105 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 7.857049e-01 | 0.105 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 7.857049e-01 | 0.105 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 7.870587e-01 | 0.104 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 7.881933e-01 | 0.103 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 7.883489e-01 | 0.103 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 7.883489e-01 | 0.103 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 7.883489e-01 | 0.103 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 7.883489e-01 | 0.103 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 7.883489e-01 | 0.103 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.883489e-01 | 0.103 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 7.891564e-01 | 0.103 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 7.891564e-01 | 0.103 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 7.901776e-01 | 0.102 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 7.903338e-01 | 0.102 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 7.949369e-01 | 0.100 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 7.949369e-01 | 0.100 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 8.037326e-01 | 0.095 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 8.037326e-01 | 0.095 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 8.049979e-01 | 0.094 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 8.049979e-01 | 0.094 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 8.049979e-01 | 0.094 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 8.049979e-01 | 0.094 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 8.061605e-01 | 0.094 | 0 | 0 |
| Immune System | R-HSA-168256 | 8.061898e-01 | 0.094 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 8.087080e-01 | 0.092 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 8.090850e-01 | 0.092 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 8.092923e-01 | 0.092 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 8.092923e-01 | 0.092 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 8.092923e-01 | 0.092 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 8.092923e-01 | 0.092 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 8.113081e-01 | 0.091 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 8.113081e-01 | 0.091 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 8.113081e-01 | 0.091 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 8.113081e-01 | 0.091 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 8.113081e-01 | 0.091 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 8.113081e-01 | 0.091 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 8.113081e-01 | 0.091 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 8.113081e-01 | 0.091 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 8.113081e-01 | 0.091 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 8.113081e-01 | 0.091 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 8.136710e-01 | 0.090 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 8.198573e-01 | 0.086 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.198573e-01 | 0.086 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 8.204667e-01 | 0.086 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 8.204667e-01 | 0.086 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 8.204667e-01 | 0.086 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.228437e-01 | 0.085 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 8.253858e-01 | 0.083 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 8.253858e-01 | 0.083 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 8.265233e-01 | 0.083 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 8.283662e-01 | 0.082 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 8.283662e-01 | 0.082 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 8.283662e-01 | 0.082 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 8.283662e-01 | 0.082 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 8.337700e-01 | 0.079 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 8.357994e-01 | 0.078 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 8.357994e-01 | 0.078 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 8.357994e-01 | 0.078 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 8.357994e-01 | 0.078 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 8.357994e-01 | 0.078 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 8.357994e-01 | 0.078 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 8.357994e-01 | 0.078 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 8.357994e-01 | 0.078 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 8.357994e-01 | 0.078 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 8.357994e-01 | 0.078 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 8.357994e-01 | 0.078 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 8.357994e-01 | 0.078 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 8.359686e-01 | 0.078 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.359686e-01 | 0.078 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 8.359686e-01 | 0.078 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.359686e-01 | 0.078 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.361285e-01 | 0.078 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.367801e-01 | 0.077 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.420414e-01 | 0.075 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 8.421707e-01 | 0.075 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.447170e-01 | 0.073 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 8.457032e-01 | 0.073 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 8.465100e-01 | 0.072 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 8.467734e-01 | 0.072 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 8.469657e-01 | 0.072 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 8.503018e-01 | 0.070 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 8.520616e-01 | 0.070 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 8.529698e-01 | 0.069 | 0 | 0 |
| DAG1 core M3 glycosylations | R-HSA-8932505 | 8.571130e-01 | 0.067 | 0 | 0 |
| FGFR2b ligand binding and activation | R-HSA-190377 | 8.571130e-01 | 0.067 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 8.571130e-01 | 0.067 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 8.571130e-01 | 0.067 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 8.571130e-01 | 0.067 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 8.571130e-01 | 0.067 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 8.571130e-01 | 0.067 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 8.571130e-01 | 0.067 | 0 | 0 |
| LGI-ADAM interactions | R-HSA-5682910 | 8.571130e-01 | 0.067 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 8.571130e-01 | 0.067 | 0 | 0 |
| Vitamin B1 (thiamin) metabolism | R-HSA-196819 | 8.571130e-01 | 0.067 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 8.571130e-01 | 0.067 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 8.571130e-01 | 0.067 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 8.577514e-01 | 0.067 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 8.580290e-01 | 0.066 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 8.580290e-01 | 0.066 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 8.589068e-01 | 0.066 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 8.589068e-01 | 0.066 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.614326e-01 | 0.065 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.614326e-01 | 0.065 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 8.640934e-01 | 0.063 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 8.684818e-01 | 0.061 | 0 | 0 |
| Depurination | R-HSA-73927 | 8.702101e-01 | 0.060 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 8.702101e-01 | 0.060 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 8.730290e-01 | 0.059 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 8.730290e-01 | 0.059 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 8.730290e-01 | 0.059 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 8.731645e-01 | 0.059 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 8.756611e-01 | 0.058 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 8.756611e-01 | 0.058 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 8.756611e-01 | 0.058 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 8.756611e-01 | 0.058 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 8.756611e-01 | 0.058 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 8.756611e-01 | 0.058 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 8.756611e-01 | 0.058 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 8.756795e-01 | 0.058 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 8.756795e-01 | 0.058 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 8.769249e-01 | 0.057 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 8.782768e-01 | 0.056 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 8.782768e-01 | 0.056 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 8.785407e-01 | 0.056 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 8.807243e-01 | 0.055 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 8.807243e-01 | 0.055 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 8.833730e-01 | 0.054 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.869321e-01 | 0.052 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.869321e-01 | 0.052 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 8.885638e-01 | 0.051 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.918024e-01 | 0.050 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 8.918024e-01 | 0.050 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.918024e-01 | 0.050 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 8.918024e-01 | 0.050 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 8.918024e-01 | 0.050 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.918024e-01 | 0.050 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 8.918024e-01 | 0.050 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 8.918024e-01 | 0.050 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 8.921672e-01 | 0.050 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.944664e-01 | 0.048 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 8.946525e-01 | 0.048 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 8.960096e-01 | 0.048 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 8.995482e-01 | 0.046 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.001991e-01 | 0.046 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 9.001991e-01 | 0.046 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.023695e-01 | 0.045 | 0 | 0 |
| FGFR2c ligand binding and activation | R-HSA-190375 | 9.058492e-01 | 0.043 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 9.058492e-01 | 0.043 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 9.058492e-01 | 0.043 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 9.058492e-01 | 0.043 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 9.058492e-01 | 0.043 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 9.058492e-01 | 0.043 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 9.058492e-01 | 0.043 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 9.058492e-01 | 0.043 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 9.058492e-01 | 0.043 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 9.058492e-01 | 0.043 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 9.058492e-01 | 0.043 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 9.066780e-01 | 0.043 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 9.093184e-01 | 0.041 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 9.095751e-01 | 0.041 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.106924e-01 | 0.041 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 9.106924e-01 | 0.041 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.106924e-01 | 0.041 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.114604e-01 | 0.040 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.114604e-01 | 0.040 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.152876e-01 | 0.038 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.157005e-01 | 0.038 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.157005e-01 | 0.038 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.157005e-01 | 0.038 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 9.180730e-01 | 0.037 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 9.180730e-01 | 0.037 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 9.180730e-01 | 0.037 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 9.180730e-01 | 0.037 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 9.180730e-01 | 0.037 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 9.180730e-01 | 0.037 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 9.180730e-01 | 0.037 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 9.180730e-01 | 0.037 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 9.180730e-01 | 0.037 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 9.180730e-01 | 0.037 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.184019e-01 | 0.037 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.201441e-01 | 0.036 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 9.201441e-01 | 0.036 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.201441e-01 | 0.036 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.201441e-01 | 0.036 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 9.221819e-01 | 0.035 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.228721e-01 | 0.035 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.228721e-01 | 0.035 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.232464e-01 | 0.035 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.232464e-01 | 0.035 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.270961e-01 | 0.033 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.286477e-01 | 0.032 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.286477e-01 | 0.032 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.286477e-01 | 0.032 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.286477e-01 | 0.032 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.286477e-01 | 0.032 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.286477e-01 | 0.032 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 9.287104e-01 | 0.032 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 9.287104e-01 | 0.032 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 9.287104e-01 | 0.032 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 9.287104e-01 | 0.032 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 9.287104e-01 | 0.032 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 9.287104e-01 | 0.032 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 9.287104e-01 | 0.032 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 9.287104e-01 | 0.032 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 9.287104e-01 | 0.032 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 9.287104e-01 | 0.032 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.294906e-01 | 0.032 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.294906e-01 | 0.032 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.306130e-01 | 0.031 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.308568e-01 | 0.031 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.362900e-01 | 0.029 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 9.362900e-01 | 0.029 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.362900e-01 | 0.029 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.364548e-01 | 0.029 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.370785e-01 | 0.028 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 9.379671e-01 | 0.028 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 9.379671e-01 | 0.028 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 9.379671e-01 | 0.028 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 9.379671e-01 | 0.028 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 9.379671e-01 | 0.028 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 9.379671e-01 | 0.028 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 9.379671e-01 | 0.028 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 9.379671e-01 | 0.028 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 9.379671e-01 | 0.028 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.412093e-01 | 0.026 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.415857e-01 | 0.026 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.430949e-01 | 0.025 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.431513e-01 | 0.025 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.431513e-01 | 0.025 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 9.434099e-01 | 0.025 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 9.460224e-01 | 0.024 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 9.460224e-01 | 0.024 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 9.460224e-01 | 0.024 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 9.460224e-01 | 0.024 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 9.460224e-01 | 0.024 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.460224e-01 | 0.024 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 9.460224e-01 | 0.024 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 9.460224e-01 | 0.024 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 9.460224e-01 | 0.024 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 9.460224e-01 | 0.024 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 9.460224e-01 | 0.024 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.463664e-01 | 0.024 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.466454e-01 | 0.024 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.475778e-01 | 0.023 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 9.479866e-01 | 0.023 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.485735e-01 | 0.023 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 9.493054e-01 | 0.023 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.493054e-01 | 0.023 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.493054e-01 | 0.023 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.493054e-01 | 0.023 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.494750e-01 | 0.023 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 9.504552e-01 | 0.022 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.506140e-01 | 0.022 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.506140e-01 | 0.022 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 9.530321e-01 | 0.021 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 9.530321e-01 | 0.021 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.530321e-01 | 0.021 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 9.530321e-01 | 0.021 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 9.530321e-01 | 0.021 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.532237e-01 | 0.021 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.535572e-01 | 0.021 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.535572e-01 | 0.021 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.548204e-01 | 0.020 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.548204e-01 | 0.020 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.548796e-01 | 0.020 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.580864e-01 | 0.019 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.586566e-01 | 0.018 | 0 | 0 |
| Activated point mutants of FGFR2 | R-HSA-2033519 | 9.591318e-01 | 0.018 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.591318e-01 | 0.018 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 9.591318e-01 | 0.018 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.594813e-01 | 0.018 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.596007e-01 | 0.018 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.597584e-01 | 0.018 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.597584e-01 | 0.018 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 9.597584e-01 | 0.018 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.597584e-01 | 0.018 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.603008e-01 | 0.018 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.603492e-01 | 0.018 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.621987e-01 | 0.017 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.641762e-01 | 0.016 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 9.644397e-01 | 0.016 | 0 | 0 |
| Methionine salvage pathway | R-HSA-1237112 | 9.644397e-01 | 0.016 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.645053e-01 | 0.016 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.658439e-01 | 0.015 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 9.659290e-01 | 0.015 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 9.681255e-01 | 0.014 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.685521e-01 | 0.014 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.690584e-01 | 0.014 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 9.690584e-01 | 0.014 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 9.690584e-01 | 0.014 | 0 | 0 |
| Synthesis of Ketone Bodies | R-HSA-77111 | 9.690584e-01 | 0.014 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 9.690584e-01 | 0.014 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.690584e-01 | 0.014 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.693100e-01 | 0.014 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.701644e-01 | 0.013 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 9.705267e-01 | 0.013 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.710405e-01 | 0.013 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 9.716537e-01 | 0.012 | 0 | 0 |
| FGFR2 ligand binding and activation | R-HSA-190241 | 9.730775e-01 | 0.012 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.730775e-01 | 0.012 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 9.730775e-01 | 0.012 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.738978e-01 | 0.011 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.742999e-01 | 0.011 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 9.752850e-01 | 0.011 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.758498e-01 | 0.011 | 0 | 0 |
| CS-GAG biosynthesis | R-HSA-2022870 | 9.765747e-01 | 0.010 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.765747e-01 | 0.010 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.765747e-01 | 0.010 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 9.765747e-01 | 0.010 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.776132e-01 | 0.010 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.783462e-01 | 0.010 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.793718e-01 | 0.009 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.793929e-01 | 0.009 | 0 | 0 |
| Free fatty acid receptors | R-HSA-444209 | 9.796178e-01 | 0.009 | 0 | 0 |
| Reactions specific to the complex N-glycan synthesis pathway | R-HSA-975578 | 9.796178e-01 | 0.009 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.796178e-01 | 0.009 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 9.796178e-01 | 0.009 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.808285e-01 | 0.008 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.822658e-01 | 0.008 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.822658e-01 | 0.008 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 9.822658e-01 | 0.008 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.822658e-01 | 0.008 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 9.822658e-01 | 0.008 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.822658e-01 | 0.008 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.822658e-01 | 0.008 | 0 | 0 |
| Ketone body metabolism | R-HSA-74182 | 9.822658e-01 | 0.008 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 9.823508e-01 | 0.008 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.823508e-01 | 0.008 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.827337e-01 | 0.008 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.831001e-01 | 0.007 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.837987e-01 | 0.007 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.843389e-01 | 0.007 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.843389e-01 | 0.007 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.845699e-01 | 0.007 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.845699e-01 | 0.007 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.847076e-01 | 0.007 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.848107e-01 | 0.007 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.861084e-01 | 0.006 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.861084e-01 | 0.006 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.861084e-01 | 0.006 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.861692e-01 | 0.006 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 9.865747e-01 | 0.006 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.865747e-01 | 0.006 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.865747e-01 | 0.006 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.866506e-01 | 0.006 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.873814e-01 | 0.006 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.883192e-01 | 0.005 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.883192e-01 | 0.005 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.883192e-01 | 0.005 | 0 | 0 |
| Diseases of branched-chain amino acid catabolism | R-HSA-9865118 | 9.883192e-01 | 0.005 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.883192e-01 | 0.005 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.884238e-01 | 0.005 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.885690e-01 | 0.005 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.885706e-01 | 0.005 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.890825e-01 | 0.005 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.890931e-01 | 0.005 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 9.898370e-01 | 0.004 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.898370e-01 | 0.004 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.898370e-01 | 0.004 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.898370e-01 | 0.004 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.898370e-01 | 0.004 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.903265e-01 | 0.004 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.903719e-01 | 0.004 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.906156e-01 | 0.004 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 9.908486e-01 | 0.004 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 9.908486e-01 | 0.004 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.911577e-01 | 0.004 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.914318e-01 | 0.004 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.919947e-01 | 0.003 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.923069e-01 | 0.003 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.923069e-01 | 0.003 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.924799e-01 | 0.003 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.949336e-01 | 0.002 | 0 | 0 |
| HS-GAG degradation | R-HSA-2024096 | 9.949336e-01 | 0.002 | 0 | 0 |
| Defective B3GALTL causes PpS | R-HSA-5083635 | 9.955922e-01 | 0.002 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.955922e-01 | 0.002 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.955922e-01 | 0.002 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.958890e-01 | 0.002 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 9.961652e-01 | 0.002 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.961652e-01 | 0.002 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.961652e-01 | 0.002 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.961652e-01 | 0.002 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.963662e-01 | 0.002 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 9.966638e-01 | 0.001 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.966638e-01 | 0.001 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.966638e-01 | 0.001 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.967889e-01 | 0.001 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.970400e-01 | 0.001 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.970975e-01 | 0.001 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.970975e-01 | 0.001 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.974749e-01 | 0.001 | 0 | 0 |
| O-glycosylation of TSR domain-containing proteins | R-HSA-5173214 | 9.978032e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.978032e-01 | 0.001 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.978032e-01 | 0.001 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.978032e-01 | 0.001 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.978824e-01 | 0.001 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.980465e-01 | 0.001 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.983059e-01 | 0.001 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.983374e-01 | 0.001 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.984451e-01 | 0.001 | 0 | 0 |
| N-glycan antennae elongation in the medial/trans-Golgi | R-HSA-975576 | 9.985536e-01 | 0.001 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.985536e-01 | 0.001 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.985664e-01 | 0.001 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 9.986360e-01 | 0.001 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.987365e-01 | 0.001 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.987365e-01 | 0.001 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.987417e-01 | 0.001 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.987857e-01 | 0.001 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.987857e-01 | 0.001 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.989054e-01 | 0.000 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.989054e-01 | 0.000 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.990478e-01 | 0.000 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.990792e-01 | 0.000 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.990792e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.991574e-01 | 0.000 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.991883e-01 | 0.000 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.991883e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.992018e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.992394e-01 | 0.000 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.992794e-01 | 0.000 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.992794e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.992845e-01 | 0.000 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.992845e-01 | 0.000 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.993732e-01 | 0.000 | 0 | 0 |
| The canonical retinoid cycle in rods (twilight vision) | R-HSA-2453902 | 9.993732e-01 | 0.000 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.993732e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.995106e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.995874e-01 | 0.000 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.996411e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.996658e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.996658e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.996658e-01 | 0.000 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.996693e-01 | 0.000 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.996878e-01 | 0.000 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.997058e-01 | 0.000 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.997284e-01 | 0.000 | 0 | 0 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 9.997284e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.997313e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.997721e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.997994e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.998337e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.998376e-01 | 0.000 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.998445e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.998447e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999086e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.999110e-01 | 0.000 | 0 | 0 |
| Sialic acid metabolism | R-HSA-4085001 | 9.999110e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999142e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.999184e-01 | 0.000 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.999226e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999405e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999446e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999475e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.999491e-01 | 0.000 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.999557e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999594e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999624e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999639e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.999709e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.999745e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999745e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.999747e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999768e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999804e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999808e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.999833e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.999833e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.999855e-01 | 0.000 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.999905e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999912e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999931e-01 | 0.000 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.999937e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.999937e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.999945e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.999959e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999985e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999990e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999990e-01 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.999991e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999992e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.999993e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999996e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999996e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999996e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999997e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999997e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999997e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999997e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999998e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999999e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999999e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999999e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 1.000000e+00 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | -0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.110223e-16 | 15.955 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.110223e-16 | 15.955 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.110223e-16 | 15.955 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.110223e-16 | 15.955 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 4.551914e-15 | 14.342 | 0 | 0 |
| M Phase | R-HSA-68886 | 7.771561e-15 | 14.109 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.021405e-14 | 13.991 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.476597e-14 | 13.831 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.787459e-14 | 13.748 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 4.229950e-14 | 13.374 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 4.229950e-14 | 13.374 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 8.282264e-14 | 13.082 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.552092e-13 | 12.809 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 2.362555e-13 | 12.627 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 3.663736e-13 | 12.436 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 4.624079e-13 | 12.335 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 6.014078e-13 | 12.221 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 8.284484e-13 | 12.082 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 7.918111e-13 | 12.101 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.335931e-12 | 11.874 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 1.835643e-12 | 11.736 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 4.509837e-12 | 11.346 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 5.741185e-12 | 11.241 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 5.604517e-12 | 11.251 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 6.426637e-12 | 11.192 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 8.533507e-12 | 11.069 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.410927e-11 | 10.850 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.399025e-11 | 10.620 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 4.026524e-11 | 10.395 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 4.026524e-11 | 10.395 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 6.451539e-11 | 10.190 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 7.054934e-11 | 10.152 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 6.888812e-11 | 10.162 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 9.439627e-11 | 10.025 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.177817e-10 | 9.929 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.266788e-10 | 9.897 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.714536e-10 | 9.766 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 1.806384e-10 | 9.743 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 1.788554e-10 | 9.747 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 1.851205e-10 | 9.733 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.989049e-10 | 9.701 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 2.772466e-10 | 9.557 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.792119e-10 | 9.554 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.809086e-10 | 9.419 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 4.014681e-10 | 9.396 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.446580e-10 | 9.352 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 6.085954e-10 | 9.216 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 6.174562e-10 | 9.209 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 7.567195e-10 | 9.121 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 8.212747e-10 | 9.086 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 8.212747e-10 | 9.086 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 8.484994e-10 | 9.071 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 9.227341e-10 | 9.035 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 1.334121e-09 | 8.875 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.434280e-09 | 8.843 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.943745e-09 | 8.711 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.050685e-09 | 8.688 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.253871e-09 | 8.647 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.495396e-09 | 8.603 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.940266e-09 | 8.532 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 3.190439e-09 | 8.496 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 3.432325e-09 | 8.464 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 3.788993e-09 | 8.421 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 4.660976e-09 | 8.332 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 5.005418e-09 | 8.301 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 5.269105e-09 | 8.278 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 5.204635e-09 | 8.284 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 5.631067e-09 | 8.249 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 5.965557e-09 | 8.224 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 8.966559e-09 | 8.047 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 8.998760e-09 | 8.046 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 9.422049e-09 | 8.026 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 9.483651e-09 | 8.023 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.077410e-08 | 7.968 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.206730e-08 | 7.918 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 1.328954e-08 | 7.876 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.328954e-08 | 7.876 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 1.401173e-08 | 7.854 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.582046e-08 | 7.801 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.747373e-08 | 7.758 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 2.144623e-08 | 7.669 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.879665e-08 | 7.541 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.879665e-08 | 7.541 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 3.097657e-08 | 7.509 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 3.273937e-08 | 7.485 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 3.273937e-08 | 7.485 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 3.911453e-08 | 7.408 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 5.265516e-08 | 7.279 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 5.468578e-08 | 7.262 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 6.277431e-08 | 7.202 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 7.033656e-08 | 7.153 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 9.332558e-08 | 7.030 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.942420e-08 | 7.003 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.074525e-07 | 6.969 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 1.112114e-07 | 6.954 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.158384e-07 | 6.936 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 1.410210e-07 | 6.851 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 1.686483e-07 | 6.773 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.315007e-07 | 6.635 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 2.330966e-07 | 6.632 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.471772e-07 | 6.607 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 2.342547e-07 | 6.630 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 3.403614e-07 | 6.468 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 3.831313e-07 | 6.417 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 3.889554e-07 | 6.410 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 5.087256e-07 | 6.294 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 5.276630e-07 | 6.278 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 5.614606e-07 | 6.251 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 6.033310e-07 | 6.219 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 6.610353e-07 | 6.180 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 6.700907e-07 | 6.174 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 7.311851e-07 | 6.136 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 7.311851e-07 | 6.136 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 8.692284e-07 | 6.061 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 8.807268e-07 | 6.055 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 9.254157e-07 | 6.034 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 9.686820e-07 | 6.014 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 9.686820e-07 | 6.014 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 9.686820e-07 | 6.014 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 9.686820e-07 | 6.014 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.185167e-06 | 5.926 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.470340e-06 | 5.833 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 1.635413e-06 | 5.786 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.635413e-06 | 5.786 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.666069e-06 | 5.778 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.881834e-06 | 5.725 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 2.032964e-06 | 5.692 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 2.097409e-06 | 5.678 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 2.164015e-06 | 5.665 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 2.169553e-06 | 5.664 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.199558e-06 | 5.658 | 0 | 0 |
| Protein folding | R-HSA-391251 | 2.708265e-06 | 5.567 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 3.197764e-06 | 5.495 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.197764e-06 | 5.495 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 3.468521e-06 | 5.460 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 3.238832e-06 | 5.490 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 3.572561e-06 | 5.447 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 3.629225e-06 | 5.440 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 3.888034e-06 | 5.410 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 3.942003e-06 | 5.404 | 0 | 0 |
| Immune System | R-HSA-168256 | 4.220464e-06 | 5.375 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 4.285230e-06 | 5.368 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 5.169287e-06 | 5.287 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 5.169287e-06 | 5.287 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 5.853259e-06 | 5.233 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 6.006838e-06 | 5.221 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 7.434472e-06 | 5.129 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 8.274144e-06 | 5.082 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 8.373718e-06 | 5.077 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 8.612666e-06 | 5.065 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 9.097718e-06 | 5.041 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 9.200468e-06 | 5.036 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 9.348282e-06 | 5.029 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.038501e-05 | 4.984 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 1.071974e-05 | 4.970 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.368822e-05 | 4.864 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 1.368822e-05 | 4.864 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.374511e-05 | 4.862 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.452601e-05 | 4.838 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.628043e-05 | 4.788 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.635668e-05 | 4.786 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 1.718759e-05 | 4.765 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 1.718759e-05 | 4.765 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.827018e-05 | 4.738 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.909030e-05 | 4.719 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.923909e-05 | 4.716 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.923909e-05 | 4.716 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.965007e-05 | 4.707 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.095133e-05 | 4.679 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 2.415939e-05 | 4.617 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 2.472672e-05 | 4.607 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 2.518443e-05 | 4.599 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 2.518443e-05 | 4.599 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 2.637043e-05 | 4.579 | 0 | 0 |
| Kinesins | R-HSA-983189 | 2.672302e-05 | 4.573 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 2.877930e-05 | 4.541 | 0 | 0 |
| Translation | R-HSA-72766 | 3.024271e-05 | 4.519 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 3.819103e-05 | 4.418 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 3.919306e-05 | 4.407 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 3.943182e-05 | 4.404 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 3.943182e-05 | 4.404 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 4.083675e-05 | 4.389 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 4.107066e-05 | 4.386 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 4.152010e-05 | 4.382 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 4.669155e-05 | 4.331 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 4.294096e-05 | 4.367 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 5.151781e-05 | 4.288 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 5.184719e-05 | 4.285 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 5.305111e-05 | 4.275 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 5.850615e-05 | 4.233 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 6.685804e-05 | 4.175 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 6.825429e-05 | 4.166 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 7.067436e-05 | 4.151 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 7.076294e-05 | 4.150 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 7.258684e-05 | 4.139 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 7.922695e-05 | 4.101 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 8.017723e-05 | 4.096 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 8.116806e-05 | 4.091 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 8.720418e-05 | 4.059 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 9.327599e-05 | 4.030 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 9.419690e-05 | 4.026 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 9.488963e-05 | 4.023 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 9.889738e-05 | 4.005 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.020952e-04 | 3.991 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 1.086165e-04 | 3.964 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.102335e-04 | 3.958 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 1.145587e-04 | 3.941 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.212689e-04 | 3.916 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.339455e-04 | 3.873 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.403206e-04 | 3.853 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 1.604302e-04 | 3.795 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.617916e-04 | 3.791 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 1.626004e-04 | 3.789 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.626004e-04 | 3.789 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 1.653938e-04 | 3.781 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.693914e-04 | 3.771 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 1.708435e-04 | 3.767 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.829253e-04 | 3.738 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.947214e-04 | 3.711 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.948982e-04 | 3.710 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 2.016427e-04 | 3.695 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 2.206246e-04 | 3.656 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 2.460022e-04 | 3.609 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.718709e-04 | 3.566 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 2.763948e-04 | 3.558 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 3.222234e-04 | 3.492 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 3.253265e-04 | 3.488 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 3.206669e-04 | 3.494 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 3.228521e-04 | 3.491 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 3.257203e-04 | 3.487 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.234536e-04 | 3.490 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 3.228521e-04 | 3.491 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 3.331473e-04 | 3.477 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 3.582495e-04 | 3.446 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 3.595658e-04 | 3.444 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 3.895367e-04 | 3.409 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 3.900280e-04 | 3.409 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 3.900280e-04 | 3.409 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 3.968647e-04 | 3.401 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 4.412644e-04 | 3.355 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 4.488695e-04 | 3.348 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 4.514390e-04 | 3.345 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 4.770930e-04 | 3.321 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 5.142349e-04 | 3.289 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 5.392645e-04 | 3.268 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 5.432285e-04 | 3.265 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 5.569005e-04 | 3.254 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 5.569005e-04 | 3.254 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 5.582381e-04 | 3.253 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 5.766758e-04 | 3.239 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 6.045698e-04 | 3.219 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 6.138242e-04 | 3.212 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 6.180351e-04 | 3.209 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 6.286304e-04 | 3.202 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 7.610802e-04 | 3.119 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 7.610802e-04 | 3.119 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 7.610802e-04 | 3.119 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 7.610802e-04 | 3.119 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 6.872735e-04 | 3.163 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 6.845811e-04 | 3.165 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 7.324655e-04 | 3.135 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 7.248859e-04 | 3.140 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 7.413680e-04 | 3.130 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 7.285001e-04 | 3.138 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 6.562624e-04 | 3.183 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 6.856908e-04 | 3.164 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 7.630821e-04 | 3.117 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 7.630821e-04 | 3.117 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 7.630821e-04 | 3.117 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 7.630821e-04 | 3.117 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 7.630821e-04 | 3.117 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 8.010526e-04 | 3.096 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 8.253112e-04 | 3.083 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 8.949874e-04 | 3.048 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 9.211561e-04 | 3.036 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 9.399322e-04 | 3.027 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 9.399322e-04 | 3.027 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 9.406645e-04 | 3.027 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 9.446708e-04 | 3.025 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 9.503303e-04 | 3.022 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 9.649465e-04 | 3.015 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 1.015349e-03 | 2.993 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 1.016732e-03 | 2.993 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.056600e-03 | 2.976 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.056600e-03 | 2.976 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.078414e-03 | 2.967 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 1.092562e-03 | 2.962 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 1.113049e-03 | 2.953 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.120280e-03 | 2.951 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.161484e-03 | 2.935 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.189596e-03 | 2.925 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 1.207917e-03 | 2.918 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.247552e-03 | 2.904 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 1.287046e-03 | 2.890 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 1.291899e-03 | 2.889 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.300208e-03 | 2.886 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 1.300208e-03 | 2.886 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 1.308921e-03 | 2.883 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.339253e-03 | 2.873 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.578071e-03 | 2.802 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 1.578071e-03 | 2.802 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.402010e-03 | 2.853 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 1.420265e-03 | 2.848 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.339950e-03 | 2.873 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 1.337284e-03 | 2.874 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 1.321005e-03 | 2.879 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.472423e-03 | 2.832 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 1.598005e-03 | 2.796 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 1.598005e-03 | 2.796 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 1.602442e-03 | 2.795 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.651936e-03 | 2.782 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 1.651936e-03 | 2.782 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 1.763482e-03 | 2.754 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 1.814705e-03 | 2.741 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.836285e-03 | 2.736 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.836285e-03 | 2.736 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 1.836285e-03 | 2.736 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.862985e-03 | 2.730 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.868578e-03 | 2.728 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 1.903070e-03 | 2.721 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.905871e-03 | 2.720 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.905871e-03 | 2.720 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 1.906141e-03 | 2.720 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 1.906141e-03 | 2.720 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 2.044267e-03 | 2.689 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.082754e-03 | 2.681 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 2.098046e-03 | 2.678 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 2.168937e-03 | 2.664 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 2.168937e-03 | 2.664 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 2.168937e-03 | 2.664 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.168937e-03 | 2.664 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 2.182633e-03 | 2.661 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 2.237016e-03 | 2.650 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 2.248030e-03 | 2.648 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 2.255796e-03 | 2.647 | 0 | 0 |
| Depurination | R-HSA-73927 | 2.280996e-03 | 2.642 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 2.289594e-03 | 2.640 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 2.311668e-03 | 2.636 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 2.405716e-03 | 2.619 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 2.423436e-03 | 2.616 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 2.468493e-03 | 2.608 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 2.591573e-03 | 2.586 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 2.703481e-03 | 2.568 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 2.779884e-03 | 2.556 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 3.039523e-03 | 2.517 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 3.113537e-03 | 2.507 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 3.114549e-03 | 2.507 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 3.114549e-03 | 2.507 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 3.114549e-03 | 2.507 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 3.173928e-03 | 2.498 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.188704e-03 | 2.496 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 3.222001e-03 | 2.492 | 0 | 0 |
| S Phase | R-HSA-69242 | 3.250637e-03 | 2.488 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 3.252909e-03 | 2.488 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 3.272262e-03 | 2.485 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 3.297342e-03 | 2.482 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 3.339522e-03 | 2.476 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 4.173536e-03 | 2.379 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 3.470924e-03 | 2.460 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 3.884154e-03 | 2.411 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 3.796073e-03 | 2.421 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 3.796073e-03 | 2.421 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 3.641847e-03 | 2.439 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 3.385398e-03 | 2.470 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 3.385398e-03 | 2.470 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 3.385398e-03 | 2.470 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 3.967894e-03 | 2.401 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.339522e-03 | 2.476 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 4.101129e-03 | 2.387 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 4.027566e-03 | 2.395 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 3.535880e-03 | 2.452 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 3.504918e-03 | 2.455 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 4.324007e-03 | 2.364 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 4.338047e-03 | 2.363 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.396347e-03 | 2.357 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 4.396347e-03 | 2.357 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 4.442583e-03 | 2.352 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 4.648915e-03 | 2.333 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 4.654314e-03 | 2.332 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 4.658500e-03 | 2.332 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 4.757870e-03 | 2.323 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.773934e-03 | 2.321 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.952463e-03 | 2.305 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 5.154374e-03 | 2.288 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 5.194017e-03 | 2.284 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 5.438309e-03 | 2.265 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 5.564770e-03 | 2.255 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 5.614186e-03 | 2.251 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 5.649782e-03 | 2.248 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 5.667392e-03 | 2.247 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 5.687980e-03 | 2.245 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 5.687980e-03 | 2.245 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 5.883928e-03 | 2.230 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 5.883928e-03 | 2.230 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 5.917901e-03 | 2.228 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 5.917901e-03 | 2.228 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 5.917901e-03 | 2.228 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 5.959495e-03 | 2.225 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 6.032158e-03 | 2.220 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 6.032158e-03 | 2.220 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 6.099334e-03 | 2.215 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 6.402717e-03 | 2.194 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 6.615767e-03 | 2.179 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 6.615767e-03 | 2.179 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 6.831418e-03 | 2.165 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 6.909158e-03 | 2.161 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 6.914584e-03 | 2.160 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 6.936550e-03 | 2.159 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 6.973899e-03 | 2.157 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 7.188351e-03 | 2.143 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 7.578271e-03 | 2.120 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 7.578271e-03 | 2.120 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 7.647805e-03 | 2.116 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 7.729710e-03 | 2.112 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 7.756543e-03 | 2.110 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 7.790046e-03 | 2.108 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 7.796938e-03 | 2.108 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 7.814546e-03 | 2.107 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 7.814546e-03 | 2.107 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 7.867623e-03 | 2.104 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 7.867623e-03 | 2.104 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 7.867623e-03 | 2.104 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 7.867623e-03 | 2.104 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 8.353556e-03 | 2.078 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 8.402447e-03 | 2.076 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 8.402447e-03 | 2.076 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 8.645040e-03 | 2.063 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 8.920718e-03 | 2.050 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 8.920718e-03 | 2.050 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 8.920718e-03 | 2.050 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 9.095127e-03 | 2.041 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 9.174018e-03 | 2.037 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 9.527783e-03 | 2.021 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 9.536835e-03 | 2.021 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.012120e-02 | 1.995 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 1.289943e-02 | 1.889 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 1.289943e-02 | 1.889 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.289943e-02 | 1.889 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 1.289943e-02 | 1.889 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 1.289943e-02 | 1.889 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 1.153409e-02 | 1.938 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 1.127009e-02 | 1.948 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 1.270506e-02 | 1.896 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 9.988450e-03 | 2.001 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 1.117344e-02 | 1.952 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 1.242753e-02 | 1.906 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 1.012120e-02 | 1.995 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.194808e-02 | 1.923 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 1.289943e-02 | 1.889 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.043808e-02 | 1.981 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.194808e-02 | 1.923 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 1.043808e-02 | 1.981 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 1.289943e-02 | 1.889 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 1.132714e-02 | 1.946 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 1.127009e-02 | 1.948 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.012120e-02 | 1.995 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.057997e-02 | 1.976 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 1.012120e-02 | 1.995 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 1.194808e-02 | 1.923 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 1.078751e-02 | 1.967 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 1.295770e-02 | 1.887 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 1.322937e-02 | 1.878 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 1.324040e-02 | 1.878 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 1.324040e-02 | 1.878 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 1.324040e-02 | 1.878 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.324040e-02 | 1.878 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 1.343832e-02 | 1.872 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 1.366797e-02 | 1.864 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 1.366797e-02 | 1.864 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.377900e-02 | 1.861 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.377900e-02 | 1.861 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 1.377900e-02 | 1.861 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 1.379972e-02 | 1.860 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.386073e-02 | 1.858 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.397900e-02 | 1.855 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 1.404229e-02 | 1.853 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 1.434798e-02 | 1.843 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 1.456127e-02 | 1.837 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 1.456127e-02 | 1.837 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 1.579768e-02 | 1.801 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 1.584855e-02 | 1.800 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.617211e-02 | 1.791 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.617211e-02 | 1.791 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.632670e-02 | 1.787 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.648173e-02 | 1.783 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 1.648173e-02 | 1.783 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 1.671098e-02 | 1.777 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 1.701561e-02 | 1.769 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 1.701918e-02 | 1.769 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.736679e-02 | 1.760 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 1.793067e-02 | 1.746 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 1.793067e-02 | 1.746 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 1.808904e-02 | 1.743 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.820336e-02 | 1.740 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.820336e-02 | 1.740 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 1.820336e-02 | 1.740 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 1.867364e-02 | 1.729 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.884172e-02 | 1.725 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 1.919770e-02 | 1.717 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.924483e-02 | 1.716 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 1.927998e-02 | 1.715 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.928667e-02 | 1.715 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 1.957695e-02 | 1.708 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.997689e-02 | 1.699 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 2.003122e-02 | 1.698 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 2.003122e-02 | 1.698 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 2.003122e-02 | 1.698 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 2.067955e-02 | 1.684 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 2.144061e-02 | 1.669 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 2.144061e-02 | 1.669 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 2.154849e-02 | 1.667 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 2.154849e-02 | 1.667 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 2.167881e-02 | 1.664 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 2.176208e-02 | 1.662 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 2.184943e-02 | 1.661 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 2.276880e-02 | 1.643 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 2.282179e-02 | 1.642 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 2.282179e-02 | 1.642 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.305263e-02 | 1.637 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 2.321934e-02 | 1.634 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 2.321934e-02 | 1.634 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 2.321934e-02 | 1.634 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 2.321934e-02 | 1.634 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.325902e-02 | 1.633 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 3.372238e-02 | 1.472 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 3.372238e-02 | 1.472 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 3.372238e-02 | 1.472 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 2.532754e-02 | 1.596 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 3.324111e-02 | 1.478 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 3.324111e-02 | 1.478 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 3.324111e-02 | 1.478 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 2.905076e-02 | 1.537 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.905076e-02 | 1.537 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 2.434797e-02 | 1.614 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.931558e-02 | 1.533 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 3.490565e-02 | 1.457 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.598714e-02 | 1.585 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 2.372628e-02 | 1.625 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 2.707614e-02 | 1.567 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 3.074592e-02 | 1.512 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 2.740372e-02 | 1.562 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 3.079102e-02 | 1.512 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 2.953794e-02 | 1.530 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 2.852972e-02 | 1.545 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 2.852972e-02 | 1.545 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 3.033103e-02 | 1.518 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 2.429067e-02 | 1.615 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 2.649337e-02 | 1.577 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 2.707614e-02 | 1.567 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 3.324111e-02 | 1.478 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 2.994149e-02 | 1.524 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.372628e-02 | 1.625 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.275648e-02 | 1.485 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 2.429067e-02 | 1.615 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 3.033103e-02 | 1.518 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 3.033103e-02 | 1.518 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 3.079102e-02 | 1.512 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 2.707614e-02 | 1.567 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 2.740372e-02 | 1.562 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 2.740372e-02 | 1.562 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 2.372628e-02 | 1.625 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 3.441307e-02 | 1.463 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.931558e-02 | 1.533 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 3.309535e-02 | 1.480 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 3.474839e-02 | 1.459 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 3.429059e-02 | 1.465 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 3.490565e-02 | 1.457 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 2.852972e-02 | 1.545 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 2.738821e-02 | 1.562 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 2.896554e-02 | 1.538 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 2.896554e-02 | 1.538 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 2.905076e-02 | 1.537 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 2.343701e-02 | 1.630 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 2.905076e-02 | 1.537 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 2.666916e-02 | 1.574 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 3.324111e-02 | 1.478 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 2.372628e-02 | 1.625 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 3.468244e-02 | 1.460 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 2.833231e-02 | 1.548 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 2.532754e-02 | 1.596 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 2.343701e-02 | 1.630 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 2.833231e-02 | 1.548 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 2.833231e-02 | 1.548 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 2.833231e-02 | 1.548 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.490565e-02 | 1.457 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 3.135884e-02 | 1.504 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 2.378570e-02 | 1.624 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 2.888217e-02 | 1.539 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 3.079102e-02 | 1.512 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 3.324111e-02 | 1.478 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 3.446322e-02 | 1.463 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.931558e-02 | 1.533 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 2.532754e-02 | 1.596 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 3.533908e-02 | 1.452 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 3.533908e-02 | 1.452 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 3.547110e-02 | 1.450 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 3.548433e-02 | 1.450 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 3.573125e-02 | 1.447 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 3.573125e-02 | 1.447 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 3.573125e-02 | 1.447 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.662006e-02 | 1.436 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.662006e-02 | 1.436 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 3.736461e-02 | 1.428 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.761591e-02 | 1.425 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 3.799804e-02 | 1.420 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 3.843021e-02 | 1.415 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 3.843021e-02 | 1.415 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 3.884932e-02 | 1.411 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 3.884932e-02 | 1.411 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 4.113943e-02 | 1.386 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 4.244140e-02 | 1.372 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 4.244140e-02 | 1.372 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 4.244140e-02 | 1.372 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 4.244140e-02 | 1.372 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 4.244140e-02 | 1.372 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 4.244140e-02 | 1.372 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 4.270113e-02 | 1.370 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 4.270113e-02 | 1.370 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 4.328507e-02 | 1.364 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 4.328507e-02 | 1.364 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 4.328507e-02 | 1.364 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 4.328507e-02 | 1.364 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 4.337564e-02 | 1.363 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 4.357490e-02 | 1.361 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 4.357918e-02 | 1.361 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 4.379714e-02 | 1.359 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 4.379714e-02 | 1.359 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 4.379714e-02 | 1.359 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 4.422863e-02 | 1.354 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 4.422863e-02 | 1.354 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 4.422863e-02 | 1.354 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 4.538365e-02 | 1.343 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 4.570979e-02 | 1.340 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 4.590422e-02 | 1.338 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 4.672702e-02 | 1.330 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 4.685978e-02 | 1.329 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 4.685978e-02 | 1.329 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 4.726959e-02 | 1.325 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 4.728425e-02 | 1.325 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 4.803337e-02 | 1.318 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 4.803337e-02 | 1.318 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 4.803337e-02 | 1.318 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 4.886334e-02 | 1.311 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 4.886334e-02 | 1.311 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 4.936284e-02 | 1.307 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 4.979269e-02 | 1.303 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 4.980005e-02 | 1.303 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 4.980005e-02 | 1.303 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.980005e-02 | 1.303 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 4.984095e-02 | 1.302 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 4.984095e-02 | 1.302 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 5.172709e-02 | 1.286 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 5.172709e-02 | 1.286 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 5.269224e-02 | 1.278 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 5.269224e-02 | 1.278 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 5.430192e-02 | 1.265 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 5.430192e-02 | 1.265 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 5.430192e-02 | 1.265 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 5.451009e-02 | 1.264 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 5.511223e-02 | 1.259 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 5.559891e-02 | 1.255 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 5.589457e-02 | 1.253 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 5.589457e-02 | 1.253 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 5.589457e-02 | 1.253 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 5.656051e-02 | 1.247 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 5.702545e-02 | 1.244 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 5.702545e-02 | 1.244 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 5.765638e-02 | 1.239 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 5.986432e-02 | 1.223 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 6.019799e-02 | 1.220 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 6.084914e-02 | 1.216 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 6.092240e-02 | 1.215 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 6.104640e-02 | 1.214 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 6.104640e-02 | 1.214 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 6.104640e-02 | 1.214 | 0 | 0 |
| Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) | R-HSA-1299308 | 6.104640e-02 | 1.214 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 6.106293e-02 | 1.214 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 6.106293e-02 | 1.214 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 6.106293e-02 | 1.214 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 6.184189e-02 | 1.209 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 6.188220e-02 | 1.208 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 6.188220e-02 | 1.208 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 6.213622e-02 | 1.207 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 6.213622e-02 | 1.207 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 6.239638e-02 | 1.205 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 6.239638e-02 | 1.205 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 6.239638e-02 | 1.205 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 6.348421e-02 | 1.197 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 6.384256e-02 | 1.195 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 6.386312e-02 | 1.195 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 6.386312e-02 | 1.195 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 6.386312e-02 | 1.195 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 6.386312e-02 | 1.195 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 6.470435e-02 | 1.189 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 6.470435e-02 | 1.189 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 6.589632e-02 | 1.181 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 6.639841e-02 | 1.178 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 6.639841e-02 | 1.178 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 6.887097e-02 | 1.162 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 6.935116e-02 | 1.159 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 6.935116e-02 | 1.159 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 6.935116e-02 | 1.159 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 7.041397e-02 | 1.152 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 7.128935e-02 | 1.147 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 7.171164e-02 | 1.144 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 7.171164e-02 | 1.144 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 7.276583e-02 | 1.138 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 7.276583e-02 | 1.138 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 7.291154e-02 | 1.137 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 7.305986e-02 | 1.136 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 7.305986e-02 | 1.136 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 7.305986e-02 | 1.136 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 7.510535e-02 | 1.124 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 7.510535e-02 | 1.124 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 7.510535e-02 | 1.124 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 7.550477e-02 | 1.122 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 7.631151e-02 | 1.117 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 7.631151e-02 | 1.117 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 7.631151e-02 | 1.117 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 7.654156e-02 | 1.116 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 7.673425e-02 | 1.115 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 7.676168e-02 | 1.115 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 7.676168e-02 | 1.115 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 7.676168e-02 | 1.115 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 7.676168e-02 | 1.115 | 0 | 0 |
| Drug resistance of FLT3 mutants | R-HSA-9702506 | 9.475510e-02 | 1.023 | 0 | 0 |
| FLT3 mutants bind TKIs | R-HSA-9702509 | 9.475510e-02 | 1.023 | 0 | 0 |
| ponatinib-resistant FLT3 mutants | R-HSA-9702614 | 9.475510e-02 | 1.023 | 0 | 0 |
| sorafenib-resistant FLT3 mutants | R-HSA-9702624 | 9.475510e-02 | 1.023 | 0 | 0 |
| midostaurin-resistant FLT3 mutants | R-HSA-9702600 | 9.475510e-02 | 1.023 | 0 | 0 |
| linifanib-resistant FLT3 mutants | R-HSA-9702998 | 9.475510e-02 | 1.023 | 0 | 0 |
| pexidartinib-resistant FLT3 mutants | R-HSA-9702605 | 9.475510e-02 | 1.023 | 0 | 0 |
| semaxanib-resistant FLT3 mutants | R-HSA-9702577 | 9.475510e-02 | 1.023 | 0 | 0 |
| sunitinib-resistant FLT3 mutants | R-HSA-9702632 | 9.475510e-02 | 1.023 | 0 | 0 |
| quizartinib-resistant FLT3 mutants | R-HSA-9702620 | 9.475510e-02 | 1.023 | 0 | 0 |
| tamatinib-resistant FLT3 mutants | R-HSA-9703009 | 9.475510e-02 | 1.023 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 9.475510e-02 | 1.023 | 0 | 0 |
| gilteritinib-resistant FLT3 mutants | R-HSA-9702590 | 9.475510e-02 | 1.023 | 0 | 0 |
| lestaurtinib-resistant FLT3 mutants | R-HSA-9702596 | 9.475510e-02 | 1.023 | 0 | 0 |
| tandutinib-resistant FLT3 mutants | R-HSA-9702636 | 9.475510e-02 | 1.023 | 0 | 0 |
| crenolanib-resistant FLT3 mutants | R-HSA-9702581 | 9.475510e-02 | 1.023 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 9.475510e-02 | 1.023 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 9.475510e-02 | 1.023 | 0 | 0 |
| KW2449-resistant FLT3 mutants | R-HSA-9702569 | 9.475510e-02 | 1.023 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 8.949379e-02 | 1.048 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 8.949379e-02 | 1.048 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 8.949379e-02 | 1.048 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 8.949379e-02 | 1.048 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.209819e-01 | 0.917 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 1.209819e-01 | 0.917 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.209819e-01 | 0.917 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.209819e-01 | 0.917 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.209819e-01 | 0.917 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 7.941229e-02 | 1.100 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 7.941229e-02 | 1.100 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 1.546798e-01 | 0.811 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.546798e-01 | 0.811 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 1.546798e-01 | 0.811 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 1.546798e-01 | 0.811 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 1.546798e-01 | 0.811 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 1.546798e-01 | 0.811 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 9.851949e-02 | 1.006 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 9.851949e-02 | 1.006 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 9.851949e-02 | 1.006 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 7.772114e-02 | 1.109 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 7.772114e-02 | 1.109 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 7.772114e-02 | 1.109 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 7.772114e-02 | 1.109 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 1.192704e-01 | 0.923 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.192704e-01 | 0.923 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.414670e-01 | 0.849 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 1.414670e-01 | 0.849 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.072929e-01 | 0.969 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 8.239470e-02 | 1.084 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 1.237174e-01 | 0.908 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.237174e-01 | 0.908 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 1.237174e-01 | 0.908 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 9.435950e-02 | 1.025 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 8.236543e-02 | 1.084 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.071571e-01 | 0.970 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 1.411315e-01 | 0.850 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 1.207546e-01 | 0.918 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.207546e-01 | 0.918 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 8.010679e-02 | 1.096 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 8.010679e-02 | 1.096 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.035573e-01 | 0.985 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 1.151206e-01 | 0.939 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 9.852466e-02 | 1.006 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 1.501890e-01 | 0.823 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.273028e-01 | 0.895 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.273028e-01 | 0.895 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 9.295050e-02 | 1.032 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 1.017239e-01 | 0.993 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 1.017239e-01 | 0.993 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.168070e-02 | 1.088 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 8.168070e-02 | 1.088 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.502599e-02 | 1.022 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 8.859802e-02 | 1.053 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 1.031767e-01 | 0.986 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 1.495792e-01 | 0.825 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 1.117121e-01 | 0.952 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 1.416249e-01 | 0.849 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 1.084446e-01 | 0.965 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 8.916436e-02 | 1.050 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 1.501890e-01 | 0.823 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 7.989201e-02 | 1.097 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.035573e-01 | 0.985 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 1.234807e-01 | 0.908 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 8.239470e-02 | 1.084 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 8.726372e-02 | 1.059 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.509133e-02 | 1.022 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 1.209819e-01 | 0.917 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 1.546798e-01 | 0.811 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 9.851949e-02 | 1.006 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.414670e-01 | 0.849 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 8.904623e-02 | 1.050 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 9.852466e-02 | 1.006 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 1.035573e-01 | 0.985 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 9.582114e-02 | 1.019 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 8.553821e-02 | 1.068 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 1.546798e-01 | 0.811 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 9.193729e-02 | 1.037 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 9.193729e-02 | 1.037 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 1.237174e-01 | 0.908 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 1.237174e-01 | 0.908 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 1.400799e-01 | 0.854 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 9.851949e-02 | 1.006 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 1.072929e-01 | 0.969 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.295050e-02 | 1.032 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 1.206017e-01 | 0.919 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 1.306893e-01 | 0.884 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 9.435950e-02 | 1.025 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 1.072929e-01 | 0.969 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 1.071571e-01 | 0.970 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 1.411315e-01 | 0.850 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 8.589119e-02 | 1.066 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 8.589119e-02 | 1.066 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 8.010679e-02 | 1.096 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 9.852466e-02 | 1.006 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 8.264598e-02 | 1.083 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 1.546009e-01 | 0.811 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 1.245272e-01 | 0.905 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 1.072929e-01 | 0.969 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 1.113949e-01 | 0.953 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 7.989201e-02 | 1.097 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 1.210914e-01 | 0.917 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 8.949379e-02 | 1.048 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.209819e-01 | 0.917 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 7.772114e-02 | 1.109 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 1.192704e-01 | 0.923 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 8.239470e-02 | 1.084 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 9.435950e-02 | 1.025 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 1.071571e-01 | 0.970 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 1.273028e-01 | 0.895 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 1.273028e-01 | 0.895 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.190631e-01 | 0.924 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 1.017239e-01 | 0.993 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 8.726372e-02 | 1.059 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.159989e-01 | 0.936 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 9.947256e-02 | 1.002 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 8.168070e-02 | 1.088 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 8.236543e-02 | 1.084 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 1.416249e-01 | 0.849 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.192704e-01 | 0.923 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.582114e-02 | 1.019 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 1.031767e-01 | 0.986 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.941229e-02 | 1.100 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 1.085339e-01 | 0.964 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 9.502599e-02 | 1.022 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.197701e-02 | 1.036 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 1.546798e-01 | 0.811 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 7.772114e-02 | 1.109 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 7.772114e-02 | 1.109 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 1.414670e-01 | 0.849 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 8.270902e-02 | 1.082 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 8.239470e-02 | 1.084 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 1.207546e-01 | 0.918 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 1.414670e-01 | 0.849 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 1.072929e-01 | 0.969 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 8.236543e-02 | 1.084 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 8.236543e-02 | 1.084 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 1.207546e-01 | 0.918 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 1.488417e-01 | 0.827 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 1.546798e-01 | 0.811 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.351131e-01 | 0.869 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 1.351131e-01 | 0.869 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 1.109434e-01 | 0.955 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 1.071571e-01 | 0.970 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.411315e-01 | 0.850 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 1.559985e-01 | 0.807 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 1.594497e-01 | 0.797 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.594497e-01 | 0.797 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.594497e-01 | 0.797 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 1.599351e-01 | 0.796 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 1.609526e-01 | 0.793 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 1.619083e-01 | 0.791 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 1.634105e-01 | 0.787 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 1.634105e-01 | 0.787 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 1.634105e-01 | 0.787 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 1.634105e-01 | 0.787 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 1.649070e-01 | 0.783 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 1.649070e-01 | 0.783 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 1.649070e-01 | 0.783 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 1.658557e-01 | 0.780 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 1.658557e-01 | 0.780 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.659345e-01 | 0.780 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 1.659345e-01 | 0.780 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 1.659345e-01 | 0.780 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 1.659345e-01 | 0.780 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 1.660738e-01 | 0.780 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 1.665619e-01 | 0.778 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 1.673072e-01 | 0.776 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 1.681870e-01 | 0.774 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 1.682127e-01 | 0.774 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 1.703621e-01 | 0.769 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.750894e-01 | 0.757 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 1.785815e-01 | 0.748 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.785815e-01 | 0.748 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 1.789541e-01 | 0.747 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 1.789541e-01 | 0.747 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.805367e-01 | 0.743 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.805367e-01 | 0.743 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.805367e-01 | 0.743 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.805367e-01 | 0.743 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.805367e-01 | 0.743 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH3 | R-HSA-5632927 | 1.805367e-01 | 0.743 | 0 | 0 |
| RPIA deficiency: failed conversion of R5P to RU5P | R-HSA-5659996 | 1.805367e-01 | 0.743 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.805367e-01 | 0.743 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.805367e-01 | 0.743 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 1.805367e-01 | 0.743 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 1.805367e-01 | 0.743 | 0 | 0 |
| RPIA deficiency: failed conversion of RU5P to R5P | R-HSA-6791461 | 1.805367e-01 | 0.743 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.805367e-01 | 0.743 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 1.805367e-01 | 0.743 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.805367e-01 | 0.743 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.805367e-01 | 0.743 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.805367e-01 | 0.743 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.805367e-01 | 0.743 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 1.813392e-01 | 0.742 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 1.816377e-01 | 0.741 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.816947e-01 | 0.741 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 1.822985e-01 | 0.739 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 1.893890e-01 | 0.723 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 1.898866e-01 | 0.722 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.898866e-01 | 0.722 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 1.898866e-01 | 0.722 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.898866e-01 | 0.722 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 1.898866e-01 | 0.722 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 1.922406e-01 | 0.716 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 1.929582e-01 | 0.715 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 1.965527e-01 | 0.707 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.984335e-01 | 0.702 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 1.992272e-01 | 0.701 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 1.992272e-01 | 0.701 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 2.011618e-01 | 0.696 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 2.045724e-01 | 0.689 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 2.059079e-01 | 0.686 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 2.059079e-01 | 0.686 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 2.118448e-01 | 0.674 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.147165e-01 | 0.668 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 2.147165e-01 | 0.668 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 2.147165e-01 | 0.668 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 2.147165e-01 | 0.668 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 2.166648e-01 | 0.664 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 2.166648e-01 | 0.664 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 2.189111e-01 | 0.660 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 2.189111e-01 | 0.660 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 2.199296e-01 | 0.658 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 2.215292e-01 | 0.655 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 2.221822e-01 | 0.653 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 2.260144e-01 | 0.646 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 2.260144e-01 | 0.646 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 2.260144e-01 | 0.646 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 2.260144e-01 | 0.646 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 2.260144e-01 | 0.646 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 2.260144e-01 | 0.646 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 2.260144e-01 | 0.646 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 2.260144e-01 | 0.646 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 2.266755e-01 | 0.645 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 2.266755e-01 | 0.645 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 2.266755e-01 | 0.645 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 2.275332e-01 | 0.643 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 2.275332e-01 | 0.643 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 2.342780e-01 | 0.630 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 2.342780e-01 | 0.630 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.345541e-01 | 0.630 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.345541e-01 | 0.630 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 2.345541e-01 | 0.630 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 2.399192e-01 | 0.620 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 2.407009e-01 | 0.619 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 2.407009e-01 | 0.619 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 2.407009e-01 | 0.619 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 2.407009e-01 | 0.619 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 2.407009e-01 | 0.619 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 2.424090e-01 | 0.615 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 2.520209e-01 | 0.599 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 2.528375e-01 | 0.597 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 2.528375e-01 | 0.597 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.536494e-01 | 0.596 | 0 | 0 |
| Abasic sugar-phosphate removal via the single-nucleotide replacement pathway | R-HSA-73930 | 2.581942e-01 | 0.588 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 2.581942e-01 | 0.588 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.581942e-01 | 0.588 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 2.581942e-01 | 0.588 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.581942e-01 | 0.588 | 0 | 0 |
| Defective HK1 causes hexokinase deficiency (HK deficiency) | R-HSA-5619056 | 2.581942e-01 | 0.588 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.581942e-01 | 0.588 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.581942e-01 | 0.588 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 2.581942e-01 | 0.588 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.581942e-01 | 0.588 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 2.581942e-01 | 0.588 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 2.581942e-01 | 0.588 | 0 | 0 |
| Nef mediated downregulation of CD28 cell surface expression | R-HSA-164939 | 2.581942e-01 | 0.588 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 2.599428e-01 | 0.585 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.613639e-01 | 0.583 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 2.613639e-01 | 0.583 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 2.613639e-01 | 0.583 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 2.625729e-01 | 0.581 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.625729e-01 | 0.581 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.625729e-01 | 0.581 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 2.625729e-01 | 0.581 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 2.625729e-01 | 0.581 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.625729e-01 | 0.581 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.625729e-01 | 0.581 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 2.625729e-01 | 0.581 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 2.625729e-01 | 0.581 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 2.625729e-01 | 0.581 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 2.625729e-01 | 0.581 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 2.625729e-01 | 0.581 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 2.625729e-01 | 0.581 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.625729e-01 | 0.581 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 2.638410e-01 | 0.579 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 2.664887e-01 | 0.574 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 2.668239e-01 | 0.574 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 2.671636e-01 | 0.573 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 2.714568e-01 | 0.566 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 2.714568e-01 | 0.566 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 2.789971e-01 | 0.554 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 2.789971e-01 | 0.554 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 2.789971e-01 | 0.554 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 2.831534e-01 | 0.548 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 2.903546e-01 | 0.537 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 2.903546e-01 | 0.537 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 2.939375e-01 | 0.532 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 2.939375e-01 | 0.532 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 2.939375e-01 | 0.532 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 2.939375e-01 | 0.532 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 2.939375e-01 | 0.532 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 2.943634e-01 | 0.531 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 2.943634e-01 | 0.531 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 2.991563e-01 | 0.524 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 2.991563e-01 | 0.524 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 2.991563e-01 | 0.524 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 2.991563e-01 | 0.524 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 2.991563e-01 | 0.524 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 2.991563e-01 | 0.524 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 2.991563e-01 | 0.524 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 2.991563e-01 | 0.524 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 2.991563e-01 | 0.524 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 2.991563e-01 | 0.524 | 0 | 0 |
| RSK activation | R-HSA-444257 | 2.991563e-01 | 0.524 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 2.991563e-01 | 0.524 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 3.051986e-01 | 0.515 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 3.051986e-01 | 0.515 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 3.054660e-01 | 0.515 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 3.090652e-01 | 0.510 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 3.105422e-01 | 0.508 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 3.105422e-01 | 0.508 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 3.161732e-01 | 0.500 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 3.202499e-01 | 0.495 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 3.208680e-01 | 0.494 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 3.208680e-01 | 0.494 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 3.208680e-01 | 0.494 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 3.208680e-01 | 0.494 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 3.208680e-01 | 0.494 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 3.274140e-01 | 0.485 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 3.274140e-01 | 0.485 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.277787e-01 | 0.484 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.284966e-01 | 0.483 | 0 | 0 |
| Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 | R-HSA-5083633 | 3.284966e-01 | 0.483 | 0 | 0 |
| Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 | R-HSA-5083629 | 3.284966e-01 | 0.483 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 3.284966e-01 | 0.483 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.284966e-01 | 0.483 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 3.284966e-01 | 0.483 | 0 | 0 |
| Defective AHCY causes HMAHCHD | R-HSA-5578997 | 3.284966e-01 | 0.483 | 0 | 0 |
| Signaling by RAS GAP mutants | R-HSA-9753510 | 3.284966e-01 | 0.483 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 3.284966e-01 | 0.483 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 3.284966e-01 | 0.483 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 3.284966e-01 | 0.483 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 3.284966e-01 | 0.483 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 3.284966e-01 | 0.483 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.284966e-01 | 0.483 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 3.354319e-01 | 0.474 | 0 | 0 |
| Hypusine synthesis from eIF5A-lysine | R-HSA-204626 | 3.354319e-01 | 0.474 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 3.354319e-01 | 0.474 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 3.354319e-01 | 0.474 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 3.354319e-01 | 0.474 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 3.354319e-01 | 0.474 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 3.354319e-01 | 0.474 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 3.354319e-01 | 0.474 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 3.354319e-01 | 0.474 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.354319e-01 | 0.474 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 3.354319e-01 | 0.474 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 3.369000e-01 | 0.472 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 3.369000e-01 | 0.472 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 3.414258e-01 | 0.467 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.478135e-01 | 0.459 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 3.478135e-01 | 0.459 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 3.478135e-01 | 0.459 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 3.481578e-01 | 0.458 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 3.481578e-01 | 0.458 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 3.491603e-01 | 0.457 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 3.491603e-01 | 0.457 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 3.497183e-01 | 0.456 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 3.573364e-01 | 0.447 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 3.614921e-01 | 0.442 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 3.676160e-01 | 0.435 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 3.711296e-01 | 0.430 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.711296e-01 | 0.430 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 3.711296e-01 | 0.430 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 3.711296e-01 | 0.430 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 3.711296e-01 | 0.430 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 3.711296e-01 | 0.430 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.711296e-01 | 0.430 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 3.711296e-01 | 0.430 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 3.720345e-01 | 0.429 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 3.733104e-01 | 0.428 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 3.746456e-01 | 0.426 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 3.746456e-01 | 0.426 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 3.746456e-01 | 0.426 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 3.746456e-01 | 0.426 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 3.746456e-01 | 0.426 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 3.800558e-01 | 0.420 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 3.816910e-01 | 0.418 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 3.834066e-01 | 0.416 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 3.870844e-01 | 0.412 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.893200e-01 | 0.410 | 0 | 0 |
| Activated NTRK3 signals through PLCG1 | R-HSA-9034793 | 3.921400e-01 | 0.407 | 0 | 0 |
| PLC-gamma1 signalling | R-HSA-167021 | 3.921400e-01 | 0.407 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 3.921400e-01 | 0.407 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.921400e-01 | 0.407 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 3.921400e-01 | 0.407 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.921400e-01 | 0.407 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 3.921400e-01 | 0.407 | 0 | 0 |
| Defective HPRT1 disrupts guanine and hypoxanthine salvage | R-HSA-9734281 | 3.921400e-01 | 0.407 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.921400e-01 | 0.407 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 3.921400e-01 | 0.407 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 3.921400e-01 | 0.407 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 3.921400e-01 | 0.407 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 3.921400e-01 | 0.407 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 3.940555e-01 | 0.404 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 3.942905e-01 | 0.404 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 3.942905e-01 | 0.404 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 3.949624e-01 | 0.403 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 4.012493e-01 | 0.397 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 4.012493e-01 | 0.397 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 4.012493e-01 | 0.397 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 4.012493e-01 | 0.397 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 4.012493e-01 | 0.397 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 4.023776e-01 | 0.395 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 4.060334e-01 | 0.391 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 4.060334e-01 | 0.391 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 4.060334e-01 | 0.391 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 4.060334e-01 | 0.391 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 4.060334e-01 | 0.391 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 4.060334e-01 | 0.391 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 4.060334e-01 | 0.391 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 4.164194e-01 | 0.380 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 4.164194e-01 | 0.380 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 4.164194e-01 | 0.380 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 4.164194e-01 | 0.380 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 4.258642e-01 | 0.371 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 4.258642e-01 | 0.371 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 4.262624e-01 | 0.370 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 4.275220e-01 | 0.369 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 4.275220e-01 | 0.369 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 4.302264e-01 | 0.366 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 4.314381e-01 | 0.365 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 4.324234e-01 | 0.364 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 4.383593e-01 | 0.358 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 4.399732e-01 | 0.357 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.399732e-01 | 0.357 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 4.399732e-01 | 0.357 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 4.399732e-01 | 0.357 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 4.399732e-01 | 0.357 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 4.399732e-01 | 0.357 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 4.399732e-01 | 0.357 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 4.399732e-01 | 0.357 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 4.399732e-01 | 0.357 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 4.399732e-01 | 0.357 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 4.497426e-01 | 0.347 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 4.497426e-01 | 0.347 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 4.497426e-01 | 0.347 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 4.497548e-01 | 0.347 | 0 | 0 |
| Activated NTRK2 signals through PLCG1 | R-HSA-9026527 | 4.497548e-01 | 0.347 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 4.497548e-01 | 0.347 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 4.497548e-01 | 0.347 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.497548e-01 | 0.347 | 0 | 0 |
| Extrinsic Pathway of Fibrin Clot Formation | R-HSA-140834 | 4.497548e-01 | 0.347 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 4.497548e-01 | 0.347 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 4.497548e-01 | 0.347 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 4.497548e-01 | 0.347 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 4.497548e-01 | 0.347 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 4.497548e-01 | 0.347 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 4.497548e-01 | 0.347 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 4.497548e-01 | 0.347 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 4.497548e-01 | 0.347 | 0 | 0 |
| Toxicity of tetanus toxin (tetX) | R-HSA-5250982 | 4.497548e-01 | 0.347 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.533740e-01 | 0.344 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 4.533740e-01 | 0.344 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 4.533740e-01 | 0.344 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 4.533740e-01 | 0.344 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 4.579683e-01 | 0.339 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 4.600536e-01 | 0.337 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 4.634404e-01 | 0.334 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 4.641477e-01 | 0.333 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 4.705351e-01 | 0.327 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 4.728182e-01 | 0.325 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 4.728182e-01 | 0.325 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 4.728182e-01 | 0.325 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 4.728182e-01 | 0.325 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 4.728182e-01 | 0.325 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 4.728182e-01 | 0.325 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 4.728182e-01 | 0.325 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 4.728182e-01 | 0.325 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 4.728182e-01 | 0.325 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 4.728182e-01 | 0.325 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 4.728182e-01 | 0.325 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 4.728182e-01 | 0.325 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 4.728182e-01 | 0.325 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 4.787271e-01 | 0.320 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 4.787271e-01 | 0.320 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 4.787271e-01 | 0.320 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 4.787271e-01 | 0.320 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.814509e-01 | 0.317 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 4.814509e-01 | 0.317 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 4.814509e-01 | 0.317 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 4.814509e-01 | 0.317 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.830059e-01 | 0.316 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 4.830059e-01 | 0.316 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 4.851362e-01 | 0.314 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 4.854749e-01 | 0.314 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 4.854749e-01 | 0.314 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 5.002150e-01 | 0.301 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 5.008743e-01 | 0.300 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 5.016289e-01 | 0.300 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 5.016289e-01 | 0.300 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 5.016289e-01 | 0.300 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 5.016289e-01 | 0.300 | 0 | 0 |
| IRS activation | R-HSA-74713 | 5.019118e-01 | 0.299 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 5.019118e-01 | 0.299 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 5.019118e-01 | 0.299 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 5.019118e-01 | 0.299 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 5.019118e-01 | 0.299 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 5.019118e-01 | 0.299 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 5.019118e-01 | 0.299 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 5.019118e-01 | 0.299 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 5.019118e-01 | 0.299 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 5.019118e-01 | 0.299 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 5.019118e-01 | 0.299 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 5.019118e-01 | 0.299 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 5.019118e-01 | 0.299 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 5.019118e-01 | 0.299 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 5.019118e-01 | 0.299 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 5.019118e-01 | 0.299 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 5.019118e-01 | 0.299 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 5.035142e-01 | 0.298 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 5.035142e-01 | 0.298 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 5.035142e-01 | 0.298 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 5.035142e-01 | 0.298 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 5.037470e-01 | 0.298 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 5.044712e-01 | 0.297 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 5.044712e-01 | 0.297 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 5.044712e-01 | 0.297 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 5.044712e-01 | 0.297 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 5.156106e-01 | 0.288 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 5.156106e-01 | 0.288 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 5.156106e-01 | 0.288 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 5.156106e-01 | 0.288 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 5.156106e-01 | 0.288 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 5.156106e-01 | 0.288 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 5.175554e-01 | 0.286 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 5.225079e-01 | 0.282 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 5.231743e-01 | 0.281 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 5.231743e-01 | 0.281 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 5.276790e-01 | 0.278 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 5.276790e-01 | 0.278 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 5.276790e-01 | 0.278 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 5.299773e-01 | 0.276 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 5.308333e-01 | 0.275 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 5.348630e-01 | 0.272 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 5.348630e-01 | 0.272 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 5.348630e-01 | 0.272 | 0 | 0 |
| Beta oxidation of hexanoyl-CoA to butanoyl-CoA | R-HSA-77350 | 5.348630e-01 | 0.272 | 0 | 0 |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA | R-HSA-77348 | 5.348630e-01 | 0.272 | 0 | 0 |
| Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA | R-HSA-77310 | 5.348630e-01 | 0.272 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 5.348630e-01 | 0.272 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 5.348630e-01 | 0.272 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 5.380471e-01 | 0.269 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 5.434229e-01 | 0.265 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 5.434229e-01 | 0.265 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.491277e-01 | 0.260 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 5.491277e-01 | 0.260 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.491277e-01 | 0.260 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.491277e-01 | 0.260 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 5.491277e-01 | 0.260 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 5.491277e-01 | 0.260 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 5.491277e-01 | 0.260 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 5.491277e-01 | 0.260 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 5.491277e-01 | 0.260 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 5.491277e-01 | 0.260 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 5.491277e-01 | 0.260 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 5.491277e-01 | 0.260 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 5.491277e-01 | 0.260 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 5.491277e-01 | 0.260 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.491277e-01 | 0.260 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 5.491277e-01 | 0.260 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 5.491277e-01 | 0.260 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 5.491277e-01 | 0.260 | 0 | 0 |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors | R-HSA-389397 | 5.491277e-01 | 0.260 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 5.491277e-01 | 0.260 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 5.491277e-01 | 0.260 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 5.491277e-01 | 0.260 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 5.491277e-01 | 0.260 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 5.511745e-01 | 0.259 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 5.511745e-01 | 0.259 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 5.524548e-01 | 0.258 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 5.606918e-01 | 0.251 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 5.632189e-01 | 0.249 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 5.632189e-01 | 0.249 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 5.639484e-01 | 0.249 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 5.639484e-01 | 0.249 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 5.639484e-01 | 0.249 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 5.684015e-01 | 0.245 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 5.731864e-01 | 0.242 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 5.739631e-01 | 0.241 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 5.739631e-01 | 0.241 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 5.739631e-01 | 0.241 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 5.739631e-01 | 0.241 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 5.752965e-01 | 0.240 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 5.776811e-01 | 0.238 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 5.825351e-01 | 0.235 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 5.858940e-01 | 0.232 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 5.896663e-01 | 0.229 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 5.902210e-01 | 0.229 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 5.902210e-01 | 0.229 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 5.917019e-01 | 0.228 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 5.917019e-01 | 0.228 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 5.917019e-01 | 0.228 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 5.917019e-01 | 0.228 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 5.917019e-01 | 0.228 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 5.917019e-01 | 0.228 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 5.917019e-01 | 0.228 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 5.918704e-01 | 0.228 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.918704e-01 | 0.228 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.918704e-01 | 0.228 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 5.918704e-01 | 0.228 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 5.918704e-01 | 0.228 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.918704e-01 | 0.228 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.918704e-01 | 0.228 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 5.918704e-01 | 0.228 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 5.960149e-01 | 0.225 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 5.960149e-01 | 0.225 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 5.960149e-01 | 0.225 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 5.960149e-01 | 0.225 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 5.960149e-01 | 0.225 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 5.960149e-01 | 0.225 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 5.960149e-01 | 0.225 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 6.013486e-01 | 0.221 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 6.013486e-01 | 0.221 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 6.099032e-01 | 0.215 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 6.115960e-01 | 0.214 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 6.123377e-01 | 0.213 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 6.173079e-01 | 0.209 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 6.173079e-01 | 0.209 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 6.173079e-01 | 0.209 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 6.173079e-01 | 0.209 | 0 | 0 |
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA | R-HSA-77346 | 6.181147e-01 | 0.209 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 6.181147e-01 | 0.209 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 6.181147e-01 | 0.209 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 6.181147e-01 | 0.209 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 6.181147e-01 | 0.209 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 6.181147e-01 | 0.209 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 6.181147e-01 | 0.209 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 6.196405e-01 | 0.208 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 6.196405e-01 | 0.208 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 6.227916e-01 | 0.206 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 6.270966e-01 | 0.203 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 6.305633e-01 | 0.200 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 6.305633e-01 | 0.200 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 6.305633e-01 | 0.200 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.305633e-01 | 0.200 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 6.305633e-01 | 0.200 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 6.305633e-01 | 0.200 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 6.305633e-01 | 0.200 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 6.305633e-01 | 0.200 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 6.305633e-01 | 0.200 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 6.305633e-01 | 0.200 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 6.354478e-01 | 0.197 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 6.373956e-01 | 0.196 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 6.378266e-01 | 0.195 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 6.378266e-01 | 0.195 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 6.378266e-01 | 0.195 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 6.415250e-01 | 0.193 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 6.431915e-01 | 0.192 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 6.431915e-01 | 0.192 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 6.431915e-01 | 0.192 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 6.431915e-01 | 0.192 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 6.431915e-01 | 0.192 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 6.437572e-01 | 0.191 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 6.544079e-01 | 0.184 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 6.544079e-01 | 0.184 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.556138e-01 | 0.183 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 6.556138e-01 | 0.183 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 6.575615e-01 | 0.182 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 6.575615e-01 | 0.182 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.655900e-01 | 0.177 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.655900e-01 | 0.177 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 6.655900e-01 | 0.177 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 6.655900e-01 | 0.177 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 6.655900e-01 | 0.177 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 6.655900e-01 | 0.177 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 6.655900e-01 | 0.177 | 0 | 0 |
| Fructose biosynthesis | R-HSA-5652227 | 6.655900e-01 | 0.177 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 6.655900e-01 | 0.177 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 6.655900e-01 | 0.177 | 0 | 0 |
| Nucleotide salvage defects | R-HSA-9734207 | 6.655900e-01 | 0.177 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 6.655900e-01 | 0.177 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.655900e-01 | 0.177 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 6.655900e-01 | 0.177 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 6.655900e-01 | 0.177 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 6.655900e-01 | 0.177 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.655900e-01 | 0.177 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 6.669482e-01 | 0.176 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 6.669482e-01 | 0.176 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 6.669482e-01 | 0.176 | 0 | 0 |
| PKA activation | R-HSA-163615 | 6.669482e-01 | 0.176 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 6.669482e-01 | 0.176 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 6.669482e-01 | 0.176 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 6.693554e-01 | 0.174 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 6.712519e-01 | 0.173 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 6.712519e-01 | 0.173 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 6.765088e-01 | 0.170 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 6.773875e-01 | 0.169 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 6.827434e-01 | 0.166 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 6.837469e-01 | 0.165 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 6.839734e-01 | 0.165 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 6.849715e-01 | 0.164 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 6.849715e-01 | 0.164 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 6.870237e-01 | 0.163 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 6.873393e-01 | 0.163 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 6.873393e-01 | 0.163 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 6.873393e-01 | 0.163 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 6.873393e-01 | 0.163 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 6.893096e-01 | 0.162 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 6.894096e-01 | 0.162 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 6.894096e-01 | 0.162 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 6.894096e-01 | 0.162 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 6.894096e-01 | 0.162 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 6.894096e-01 | 0.162 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 6.894096e-01 | 0.162 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 6.894096e-01 | 0.162 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 6.894096e-01 | 0.162 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 6.946691e-01 | 0.158 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 6.946691e-01 | 0.158 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 6.957409e-01 | 0.158 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 6.957731e-01 | 0.158 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 6.957731e-01 | 0.158 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 6.972977e-01 | 0.157 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.972977e-01 | 0.157 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 6.972977e-01 | 0.157 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 6.972977e-01 | 0.157 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 6.972977e-01 | 0.157 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 6.972977e-01 | 0.157 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 6.972977e-01 | 0.157 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.972977e-01 | 0.157 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 6.972977e-01 | 0.157 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 6.972977e-01 | 0.157 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 6.972977e-01 | 0.157 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 6.972977e-01 | 0.157 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 7.106078e-01 | 0.148 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 7.106078e-01 | 0.148 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 7.106078e-01 | 0.148 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 7.106078e-01 | 0.148 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 7.106078e-01 | 0.148 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 7.167329e-01 | 0.145 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 7.173246e-01 | 0.144 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 7.178190e-01 | 0.144 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 7.178190e-01 | 0.144 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 7.178190e-01 | 0.144 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 7.178190e-01 | 0.144 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 7.178190e-01 | 0.144 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 7.180302e-01 | 0.144 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 7.180302e-01 | 0.144 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 7.260006e-01 | 0.139 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 7.260006e-01 | 0.139 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 7.260006e-01 | 0.139 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 7.260006e-01 | 0.139 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 7.260006e-01 | 0.139 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 7.260006e-01 | 0.139 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 7.260006e-01 | 0.139 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 7.260006e-01 | 0.139 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 7.260006e-01 | 0.139 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 7.276074e-01 | 0.138 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 7.286525e-01 | 0.137 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 7.286525e-01 | 0.137 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 7.286525e-01 | 0.137 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 7.305803e-01 | 0.136 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 7.305803e-01 | 0.136 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 7.305803e-01 | 0.136 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 7.305803e-01 | 0.136 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 7.305803e-01 | 0.136 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 7.322133e-01 | 0.135 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 7.322133e-01 | 0.135 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 7.403941e-01 | 0.131 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 7.444958e-01 | 0.128 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 7.460487e-01 | 0.127 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 7.493689e-01 | 0.125 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 7.493689e-01 | 0.125 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 7.493689e-01 | 0.125 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 7.493689e-01 | 0.125 | 0 | 0 |
| DAG1 core M3 glycosylations | R-HSA-8932505 | 7.519834e-01 | 0.124 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 7.519834e-01 | 0.124 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 7.519834e-01 | 0.124 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 7.519834e-01 | 0.124 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 7.519834e-01 | 0.124 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.519834e-01 | 0.124 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 7.519834e-01 | 0.124 | 0 | 0 |
| Vitamin B1 (thiamin) metabolism | R-HSA-196819 | 7.519834e-01 | 0.124 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 7.519834e-01 | 0.124 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.519834e-01 | 0.124 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 7.522756e-01 | 0.124 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 7.554604e-01 | 0.122 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 7.582753e-01 | 0.120 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 7.595920e-01 | 0.119 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 7.595920e-01 | 0.119 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 7.644668e-01 | 0.117 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 7.670186e-01 | 0.115 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 7.670186e-01 | 0.115 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 7.670186e-01 | 0.115 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 7.670186e-01 | 0.115 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 7.670186e-01 | 0.115 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.670186e-01 | 0.115 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 7.672718e-01 | 0.115 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 7.720685e-01 | 0.112 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 7.739577e-01 | 0.111 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 7.739577e-01 | 0.111 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 7.739577e-01 | 0.111 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.755037e-01 | 0.110 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 7.755037e-01 | 0.110 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 7.755037e-01 | 0.110 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 7.755037e-01 | 0.110 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 7.755037e-01 | 0.110 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 7.755037e-01 | 0.110 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.755037e-01 | 0.110 | 0 | 0 |
| Endosomal/Vacuolar pathway | R-HSA-1236977 | 7.755037e-01 | 0.110 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 7.806158e-01 | 0.108 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.835762e-01 | 0.106 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.835762e-01 | 0.106 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 7.835762e-01 | 0.106 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 7.952647e-01 | 0.099 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 7.954012e-01 | 0.099 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 7.959443e-01 | 0.099 | 0 | 0 |
| Beta oxidation of palmitoyl-CoA to myristoyl-CoA | R-HSA-77305 | 7.967947e-01 | 0.099 | 0 | 0 |
| Beta oxidation of myristoyl-CoA to lauroyl-CoA | R-HSA-77285 | 7.967947e-01 | 0.099 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 7.967947e-01 | 0.099 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 7.967947e-01 | 0.099 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.967947e-01 | 0.099 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 7.967947e-01 | 0.099 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 7.967947e-01 | 0.099 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.967947e-01 | 0.099 | 0 | 0 |
| Synthesis of GDP-mannose | R-HSA-446205 | 7.967947e-01 | 0.099 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 7.967947e-01 | 0.099 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 7.967947e-01 | 0.099 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 7.990902e-01 | 0.097 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 7.990902e-01 | 0.097 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.990902e-01 | 0.097 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 8.005736e-01 | 0.097 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 8.054794e-01 | 0.094 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.054794e-01 | 0.094 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 8.057633e-01 | 0.094 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 8.061041e-01 | 0.094 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 8.136096e-01 | 0.090 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 8.136096e-01 | 0.090 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 8.136096e-01 | 0.090 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 8.136096e-01 | 0.090 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 8.136096e-01 | 0.090 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.136096e-01 | 0.090 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 8.151826e-01 | 0.089 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 8.160677e-01 | 0.088 | 0 | 0 |
| Microbial factors inhibit CASP4 activity | R-HSA-9956593 | 8.160677e-01 | 0.088 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 8.160677e-01 | 0.088 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 8.160677e-01 | 0.088 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 8.160677e-01 | 0.088 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 8.160677e-01 | 0.088 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 8.160677e-01 | 0.088 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.160677e-01 | 0.088 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 8.164509e-01 | 0.088 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 8.245088e-01 | 0.084 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.271833e-01 | 0.082 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 8.271833e-01 | 0.082 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 8.335137e-01 | 0.079 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 8.335137e-01 | 0.079 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 8.335137e-01 | 0.079 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.335137e-01 | 0.079 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.335137e-01 | 0.079 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.335137e-01 | 0.079 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.335137e-01 | 0.079 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.335137e-01 | 0.079 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 8.335137e-01 | 0.079 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 8.335137e-01 | 0.079 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 8.335137e-01 | 0.079 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 8.337324e-01 | 0.079 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 8.355272e-01 | 0.078 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 8.398601e-01 | 0.076 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 8.398601e-01 | 0.076 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.400055e-01 | 0.076 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 8.451113e-01 | 0.073 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.493059e-01 | 0.071 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 8.493059e-01 | 0.071 | 0 | 0 |
| Beta oxidation of butanoyl-CoA to acetyl-CoA | R-HSA-77352 | 8.493059e-01 | 0.071 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 8.493059e-01 | 0.071 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 8.516881e-01 | 0.070 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 8.516881e-01 | 0.070 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 8.516881e-01 | 0.070 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 8.516881e-01 | 0.070 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 8.557826e-01 | 0.068 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 8.623285e-01 | 0.064 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 8.627140e-01 | 0.064 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 8.627140e-01 | 0.064 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 8.627140e-01 | 0.064 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 8.636010e-01 | 0.064 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.636010e-01 | 0.064 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 8.636010e-01 | 0.064 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 8.636010e-01 | 0.064 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 8.636010e-01 | 0.064 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 8.636010e-01 | 0.064 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 8.636010e-01 | 0.064 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 8.636010e-01 | 0.064 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.636010e-01 | 0.064 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 8.636010e-01 | 0.064 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 8.660380e-01 | 0.062 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 8.663504e-01 | 0.062 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 8.729836e-01 | 0.059 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 8.765408e-01 | 0.057 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 8.765408e-01 | 0.057 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.765408e-01 | 0.057 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 8.765408e-01 | 0.057 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 8.765408e-01 | 0.057 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of unsaturated fatty acids | R-HSA-77288 | 8.765408e-01 | 0.057 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 8.765408e-01 | 0.057 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 8.765408e-01 | 0.057 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 8.765408e-01 | 0.057 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.765408e-01 | 0.057 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.765408e-01 | 0.057 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 8.800405e-01 | 0.055 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.825412e-01 | 0.054 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.825412e-01 | 0.054 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 8.825412e-01 | 0.054 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 8.865967e-01 | 0.052 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 8.882537e-01 | 0.051 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.882537e-01 | 0.051 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 8.882537e-01 | 0.051 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 8.929046e-01 | 0.049 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 8.937147e-01 | 0.049 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 8.937147e-01 | 0.049 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 8.939761e-01 | 0.049 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 8.988560e-01 | 0.046 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 8.988560e-01 | 0.046 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 8.997815e-01 | 0.046 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 9.039963e-01 | 0.044 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.058523e-01 | 0.043 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 9.073594e-01 | 0.042 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.073594e-01 | 0.042 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 9.084529e-01 | 0.042 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 9.084529e-01 | 0.042 | 0 | 0 |
| Methionine salvage pathway | R-HSA-1237112 | 9.084529e-01 | 0.042 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 9.084529e-01 | 0.042 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 9.084529e-01 | 0.042 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 9.084529e-01 | 0.042 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.084529e-01 | 0.042 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 9.089166e-01 | 0.041 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 9.144779e-01 | 0.039 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 9.144779e-01 | 0.039 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.144779e-01 | 0.039 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 9.144779e-01 | 0.039 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.149867e-01 | 0.039 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.171398e-01 | 0.038 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 9.171398e-01 | 0.038 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 9.171398e-01 | 0.038 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 9.171398e-01 | 0.038 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 9.171398e-01 | 0.038 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.171398e-01 | 0.038 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.171398e-01 | 0.038 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.171398e-01 | 0.038 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 9.183248e-01 | 0.037 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.210802e-01 | 0.036 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 9.210802e-01 | 0.036 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 9.210802e-01 | 0.036 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 9.230140e-01 | 0.035 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.237865e-01 | 0.034 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.250028e-01 | 0.034 | 0 | 0 |
| Phenylalanine metabolism | R-HSA-8964208 | 9.250028e-01 | 0.034 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.250028e-01 | 0.034 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.272002e-01 | 0.033 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 9.317225e-01 | 0.031 | 0 | 0 |
| Eicosanoids | R-HSA-211979 | 9.321201e-01 | 0.031 | 0 | 0 |
| Miscellaneous substrates | R-HSA-211958 | 9.321201e-01 | 0.031 | 0 | 0 |
| Androgen biosynthesis | R-HSA-193048 | 9.321201e-01 | 0.031 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.321201e-01 | 0.031 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.328698e-01 | 0.030 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.355734e-01 | 0.029 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 9.381195e-01 | 0.028 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.381195e-01 | 0.028 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.382639e-01 | 0.028 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.385624e-01 | 0.028 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.385624e-01 | 0.028 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 9.385624e-01 | 0.028 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.398267e-01 | 0.027 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.415103e-01 | 0.026 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.415103e-01 | 0.026 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.437568e-01 | 0.025 | 0 | 0 |
| Fatty acids | R-HSA-211935 | 9.443935e-01 | 0.025 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.443935e-01 | 0.025 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.443935e-01 | 0.025 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.443935e-01 | 0.025 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.456869e-01 | 0.024 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.474529e-01 | 0.023 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.474718e-01 | 0.023 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.496716e-01 | 0.022 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 9.496716e-01 | 0.022 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.496716e-01 | 0.022 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.496716e-01 | 0.022 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.507471e-01 | 0.022 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.519010e-01 | 0.021 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 9.544489e-01 | 0.020 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.544489e-01 | 0.020 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.544489e-01 | 0.020 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.554665e-01 | 0.020 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.554665e-01 | 0.020 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.563109e-01 | 0.019 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 9.587730e-01 | 0.018 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.587730e-01 | 0.018 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 9.587730e-01 | 0.018 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.623200e-01 | 0.017 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 9.626869e-01 | 0.017 | 0 | 0 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | R-HSA-83936 | 9.626869e-01 | 0.017 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.653116e-01 | 0.015 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.662294e-01 | 0.015 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.662294e-01 | 0.015 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids | R-HSA-77286 | 9.681008e-01 | 0.014 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.694358e-01 | 0.013 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.694358e-01 | 0.013 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.694358e-01 | 0.013 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.714337e-01 | 0.013 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.723379e-01 | 0.012 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.751455e-01 | 0.011 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.772449e-01 | 0.010 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.773420e-01 | 0.010 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.777722e-01 | 0.010 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.791000e-01 | 0.009 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.794105e-01 | 0.009 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 9.794938e-01 | 0.009 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 9.794938e-01 | 0.009 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.794938e-01 | 0.009 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.794938e-01 | 0.009 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.812027e-01 | 0.008 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.812027e-01 | 0.008 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 9.814414e-01 | 0.008 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.814414e-01 | 0.008 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.814414e-01 | 0.008 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.817425e-01 | 0.008 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.830159e-01 | 0.007 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.832041e-01 | 0.007 | 0 | 0 |
| Phosphate bond hydrolysis by NUDT proteins | R-HSA-2393930 | 9.832041e-01 | 0.007 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.836431e-01 | 0.007 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.836619e-01 | 0.007 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.846281e-01 | 0.007 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.847994e-01 | 0.007 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.847994e-01 | 0.007 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.848820e-01 | 0.007 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.863826e-01 | 0.006 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.875502e-01 | 0.005 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.875502e-01 | 0.005 | 0 | 0 |
| Phenylalanine and tyrosine metabolism | R-HSA-8963691 | 9.875502e-01 | 0.005 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.875502e-01 | 0.005 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.880399e-01 | 0.005 | 0 | 0 |
| tRNA processing in the mitochondrion | R-HSA-6785470 | 9.887329e-01 | 0.005 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.887329e-01 | 0.005 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.887329e-01 | 0.005 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.889437e-01 | 0.005 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.894940e-01 | 0.005 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.907722e-01 | 0.004 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.907722e-01 | 0.004 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.907722e-01 | 0.004 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.911705e-01 | 0.004 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.915661e-01 | 0.004 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.916490e-01 | 0.004 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.916490e-01 | 0.004 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.919076e-01 | 0.004 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.919076e-01 | 0.004 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.934160e-01 | 0.003 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.938107e-01 | 0.003 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.938107e-01 | 0.003 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.943990e-01 | 0.002 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.943990e-01 | 0.002 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.949313e-01 | 0.002 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.952198e-01 | 0.002 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.952467e-01 | 0.002 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.953462e-01 | 0.002 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.957649e-01 | 0.002 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.959695e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.962437e-01 | 0.002 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.966008e-01 | 0.001 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.966445e-01 | 0.001 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.967443e-01 | 0.001 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.969431e-01 | 0.001 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.971910e-01 | 0.001 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.978494e-01 | 0.001 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.979374e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.982027e-01 | 0.001 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.982027e-01 | 0.001 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.982956e-01 | 0.001 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.983111e-01 | 0.001 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.984647e-01 | 0.001 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.986271e-01 | 0.001 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.988618e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.990066e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.991611e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.992409e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.992409e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.995166e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.995835e-01 | 0.000 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.996231e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.996231e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.996292e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.996590e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.996785e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.996825e-01 | 0.000 | 0 | 0 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 9.997208e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.997826e-01 | 0.000 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.998129e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.998141e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.998307e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.998307e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.998445e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.998614e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.998974e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999388e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999412e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999626e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999735e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999772e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999813e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999834e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999887e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999914e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999924e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999935e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999936e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999944e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 9.999989e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999991e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999995e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999996e-01 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.999998e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999998e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999998e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.999998e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.999999e-01 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 9.999999e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999999e-01 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
