MEKK1
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A6NMY6 | S26 | Sugiyama | ANXA2P2 ANX2L2 ANX2P2 LPC2B | EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI |
| O00267 | T709 | Sugiyama | SUPT5H SPT5 SPT5H | GGSGGMSRGRGRRDNELIGQtVRISQGPYKGYIGVVKDATE |
| O00273 | S302 | Sugiyama | DFFA DFF1 DFF45 H13 | TETVQEACERELALRLQQtQsLHsLRsIsAsKAsPPGDLQN |
| O00410 | T969 | Sugiyama | IPO5 KPNB3 RANBP5 | PLLVRVIQSADSKTKENVNAtENCIsAVGKIMKFKPDCVNV |
| O00429 | S44 | Sugiyama | DNM1L DLP1 DRP1 | QLPQIVVVGTQSSGKSsVLEsLVGRDLLPRGTGIVTRRPLI |
| O00429 | T586 | Sugiyama | DNM1L DLP1 DRP1 | ETKNVAsGGGGVGDGVQEPTtGNWRGMLKtSKAEELLAEEK |
| O14733 | S271 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | MAP2K7 JNKK2 MEK7 MKK7 PRKMK7 SKK4 | LDERGQIKLCDFGIsGRLVDsKAKtRsAGCAAYMAPERIDP |
| O14733 | T275 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | MAP2K7 JNKK2 MEK7 MKK7 PRKMK7 SKK4 | GQIKLCDFGIsGRLVDsKAKtRsAGCAAYMAPERIDPPDPT |
| O14920 | S181 | PSP | IKBKB IKKB | IHKIIDLGYAKELDQGsLCTsFVGTLQyLAPELLEQQKyTV |
| O15127 | T109 | Sugiyama | SCAMP2 | QEELDRKAAELERKERELQNtVANLHVRQNNWPPLPSWCPV |
| O15212 | T84 | Sugiyama | PFDN6 HKE2 PFD6 | LVKQELGEARAtVGKRLDyItAEIKRYESQLRDLERQsEQQ |
| O15371 | T49 | Sugiyama | EIF3D EIF3S7 | PyQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQY |
| O43175 | S12 | Sugiyama | PHGDH PGDH3 | _________MAFANLRKVLIsDsLDPCCRKILQDGGLQVVE |
| O43175 | S14 | Sugiyama | PHGDH PGDH3 | _______MAFANLRKVLIsDsLDPCCRKILQDGGLQVVEKQ |
| O43175 | T89 | Sugiyama | PHGDH PGDH3 | KLQVVGRAGtGVDNVDLEAAtRKGILVMNTPNGNSLSAAEL |
| O43390 | Y376 | Sugiyama | HNRNPR HNRPR | ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG |
| O43399 | T146 | Sugiyama | TPD52L2 | yKKTQETLsQAGQKtsAALstVGsAIsRKLGDMRNsAtFKs |
| O43707 | S447 | Sugiyama | ACTN4 | AWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAAHQ |
| O43707 | S507 | Sugiyama | ACTN4 | DsHNVNtRCQKICDQWDALGsLtHsRREALEKTEKQLEAID |
| O43707 | T445 | Sugiyama | ACTN4 | HEAWtDGKEAMLKHRDyEtAtLsDIKALIRKHEAFEsDLAA |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60664 | S175 | Sugiyama | PLIN3 M6PRBP1 TIP47 | RGAVQSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGK |
| O60664 | S254 | Sugiyama | PLIN3 M6PRBP1 TIP47 | SyFVRLGsLSERLRQHAyEHsLGKLRATKQRAQEALLQLSQ |
| O60739 | T46 | Sugiyama | EIF1B | GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK |
| O60763 | S805 | Sugiyama | USO1 VDP | EQVAELKQELATLKSQLNSQsVEITKLQTEKQELLQKTEAF |
| O60885 | S1223 | Sugiyama | BRD4 HUNK1 | ASLVQKHPTTPSSTAKSSSDsFEQFRRAAREKEEREKALKA |
| O75122 | S1027 | Sugiyama | CLASP2 KIAA0627 | sMPtHssPRsRDyNPyNysDsIsPFNKsALKEAMFDDDADQ |
| O75369 | T1585 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | RAIVHDNKDGtyAVtyIPDKtGRYMIGVTYGGDDIPLsPyR |
| O75534 | S766 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | AAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDNsMGFG |
| O75688 | S186 | Sugiyama | PPM1B PP2CB | TQDHKPCNPREKERIQNAGGsVMIQRVNGsLAVSRALGDYD |
| O75821 | T206 | Sugiyama | EIF3G EIF3S4 | LGLstGEKEKLPGELEPVQAtQNKtGKYVPPsLRDGAsRRG |
| O75821 | T210 | Sugiyama | EIF3G EIF3S4 | tGEKEKLPGELEPVQAtQNKtGKYVPPsLRDGAsRRGESMQ |
| O75914 | T119 | Sugiyama | PAK3 OPHN3 | QMCPGKLPEGIPEQWARLLQtsNItKLEQKKNPQAVLDVLK |
| O94992 | S278 | Sugiyama | HEXIM1 CLP1 EDG1 HIS1 MAQ1 | DGSEFLQRDFsEtyERyHTEsLQNMsKQELIKEyLELEKCL |
| O95373 | T968 | Sugiyama | IPO7 RANBP7 | IIDDEDNPVDEYQIFKAIFQtIQNRNPVWyQALTHGLNEEQ |
| O95757 | S587 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | RLNQTLKKGKVKsIDLPIQssLCRQLGQDLLNsyIENEGKM |
| O95831 | T188 | Sugiyama | AIFM1 AIF PDCD8 | LPYMRPPLSKELWFSDDPNVtKtLRFKQWNGKERSIYFQPP |
| O95831 | T190 | Sugiyama | AIFM1 AIF PDCD8 | YMRPPLSKELWFSDDPNVtKtLRFKQWNGKERSIYFQPPSF |
| O95881 | S136 | Sugiyama | TXNDC12 TLP19 UNQ713/PRO1376 | LFLDPSGKVHPEIINENGNPsyKyFyVsAEQVVQGMKEAQE |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | S167 | Sugiyama | LDHA PIG19 | AWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHG |
| P00338 | S69 | Sugiyama | LDHA PIG19 | ALVDVIEDKLKGEMMDLQHGsLFLRTPKIVSGKDyNVTANs |
| P00558 | T168 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | EAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGF |
| P02786 | S361 | Sugiyama | TFRC | AAEKLFGNMEGDCPSDWKTDstCRMVTSESKNVKLTVSNVL |
| P02786 | T143 | Sugiyama | TFRC | yWDDLKRKLsEKLDstDFTGtIKLLNENsyVPREAGsQKDE |
| P02786 | T336 | Sugiyama | TFRC | FNHTQFPPSRSSGLPNIPVQtISRAAAEKLFGNMEGDCPSD |
| P04040 | T43 | Sugiyama | CAT | KADVLttGAGNPVGDKLNVItVGPRGPLLVQDVVFTDEMAH |
| P04040 | T441 | Sugiyama | CAT | HSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEEQRKRLCE |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04083 | S173 | Sugiyama | ANXA1 ANX1 LPC1 | NRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDFG |
| P04083 | T172 | Sugiyama | ANXA1 ANX1 LPC1 | INRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsEDF |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T211 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | PsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtGM |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04406 | T246 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKVVKQAS |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05187 | T185 | Sugiyama | ALPP PLAP | VGVVTTTRVQHAsPAGtyAHtVNRNWysDADVPASARQEGC |
| P05455 | S325 | Sugiyama | SSB | VLEGEVEKEALKKIIEDQQEsLNKWKSKGRRFKGKGKGNKA |
| P05783 | T404 | Sugiyama | KRT18 CYK18 PIG46 | LEDGEDFNLGDALDssNsMQtIQKtTTRRIVDGKVVsETND |
| P05787 | S410 | Sugiyama | KRT8 CYK8 | TYRKLLEGEESRLEsGMQNMsIHtKTTSGYAGGLSSAYGGL |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S353 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMVsHRs |
| P06733 | S37 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NPtVEVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRY |
| P06733 | S79 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | GKGVSKAVEHINKtIAPALVsKKLNVtEQEKIDKLMIEMDG |
| P06733 | T100 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | KKLNVtEQEKIDKLMIEMDGtENKsKFGANAILGVsLAVCK |
| P06733 | T19 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | __MSILKIHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGA |
| P06733 | T26 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IHAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEA |
| P06733 | T41 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EVDLFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKG |
| P06733 | T55 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | VPsGAstGIyEALELRDNDKtRYMGKGVSKAVEHINKtIAP |
| P06733 | T72 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | NDKtRYMGKGVSKAVEHINKtIAPALVsKKLNVtEQEKIDK |
| P06733 | Y287 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | PsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKF |
| P06744 | T250 | Sugiyama | GPI | LQAAKDPSAVAKHFVALstNttKVKEFGIDPQNMFEFWDWV |
| P06748 | S260 | Sugiyama | NPM1 NPM | GPssVEDIKAKMQAsIEKGGsLPKVEAKFINyVKNCFRMtD |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S168 | Sugiyama | LDHB | TWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIHPSSCHG |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07205 | T168 | Sugiyama | PGK2 PGKB | EAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNLPHKASGF |
| P07237 | T442 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | IAKMDstANEVEAVKVHsFPtLKFFPAsADRtVIDyNGERt |
| P07237 | T453 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | EAVKVHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESG |
| P07237 | Y116 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | VRGyPtIKFFRNGDTASPKEytAGREADDIVNWLKKRTGPA |
| P07355 | S26 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | EILCKLsLEGDHstPPsAyGsVKAytNFDAERDALNIEtAI |
| P07437 | T55 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | tyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEPGtMDs |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07814 | S1473 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | CEDWIKKtTARDQDLEPGAPsMGAKSLCIPFKPLCELQPGA |
| P07814 | S335 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07864 | S167 | Sugiyama | LDHC LDH3 LDHX | VWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVHPTSCHG |
| P07900 | S505 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S641 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DNstMGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKD |
| P07900 | T109 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | LtIVDtGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS |
| P07900 | T645 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MGyMAAKKHLEINPDHsIIEtLRQKAEADKNDKSVKDLVIL |
| P07900 | Y492 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR |
| P08151 | S521 | GPS6 | GLI1 GLI | LRLDQLHQLRPIGTRGLKLPsLsHTGtTVSRRVGPPVSLER |
| P08151 | S523 | GPS6 | GLI1 GLI | LDQLHQLRPIGTRGLKLPsLsHTGtTVSRRVGPPVSLERRs |
| P08151 | S543 | GPS6 | GLI1 GLI | sHTGtTVSRRVGPPVSLERRssSSSSIsSAYtVSRRssLAS |
| P08151 | S550 | GPS6 | GLI1 GLI | SRRVGPPVSLERRssSSSSIsSAYtVSRRssLASPFPPGsP |
| P08151 | S559 | GPS6 | GLI1 GLI | LERRssSSSSIsSAYtVSRRssLASPFPPGsPPENGASSLP |
| P08151 | S560 | GPS6 | GLI1 GLI | ERRssSSSSIsSAYtVSRRssLASPFPPGsPPENGASSLPG |
| P08151 | S569 | GPS6 | GLI1 GLI | IsSAYtVSRRssLASPFPPGsPPENGASSLPGLMPAQHYLL |
| P08151 | S595 | GPS6 | GLI1 GLI | ASSLPGLMPAQHYLLRARYAsARGGGtsPtAASsLDRIGGL |
| P08151 | S602 | GPS6 | GLI1 GLI | MPAQHYLLRARYAsARGGGtsPtAASsLDRIGGLPMPPWRS |
| P08151 | S608 | GPS6 | GLI1 GLI | LLRARYAsARGGGtsPtAASsLDRIGGLPMPPWRSRAEyPG |
| P08151 | S927 | GPS6 | GLI1 GLI | ELLWEGGGREDAPAQEPSyQsPKFLGGSQVsPSRAKAPVNT |
| P08151 | S937 | GPS6 | GLI1 GLI | DAPAQEPSyQsPKFLGGSQVsPSRAKAPVNTYGPGFGPNLP |
| P08151 | T1074 | GPS6 | GLI1 GLI | DEPQGLSPPPSHDQRGSsGHtPPPsGPPNMAVGNMsVLLRS |
| P08151 | T527 | GPS6 | GLI1 GLI | HQLRPIGTRGLKLPsLsHTGtTVSRRVGPPVSLERRssSSS |
| P08151 | T554 | GPS6 | GLI1 GLI | GPPVSLERRssSSSSIsSAYtVSRRssLASPFPPGsPPENG |
| P08151 | T601 | GPS6 | GLI1 GLI | LMPAQHYLLRARYAsARGGGtsPtAASsLDRIGGLPMPPWR |
| P08151 | T604 | GPS6 | GLI1 GLI | AQHYLLRARYAsARGGGtsPtAASsLDRIGGLPMPPWRSRA |
| P08151 | Y626 | GPS6 | GLI1 GLI | ASsLDRIGGLPMPPWRSRAEyPGYNPNAGVTRRAsDPAQAA |
| P08151 | Y925 | GPS6 | GLI1 GLI | QQELLWEGGGREDAPAQEPSyQsPKFLGGSQVsPSRAKAPV |
| P08195 | S253 | Sugiyama | SLC3A2 MDU1 | FQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKDDVA |
| P08195 | S403 | Sugiyama | SLC3A2 MDU1 | SDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYL |
| P08195 | S408 | Sugiyama | SLC3A2 MDU1 | ILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNATGN |
| P08195 | S598 | Sugiyama | SLC3A2 MDU1 | LQASDLPASASLPAKADLLLstQPGREEGsPLELERLKLEP |
| P08195 | Y250 | Sugiyama | SLC3A2 MDU1 | LQAFQGHGAGNLAGLKGRLDyLssLKVKGLVLGPIHKNQKD |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S482 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | sGDEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVER |
| P08238 | S497 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI |
| P08238 | T104 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LtLVDtGIGMtKADLINNLGtIAKSGtKAFMEALQAGADIS |
| P08238 | T467 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt |
| P08238 | T616 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | yGWTANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVE |
| P08238 | Y619 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR |
| P08758 | T10 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | ___________MAQVLRGtVtDFPGFDERADAEtLRKAMKG |
| P09104 | S37 | Sugiyama | ENO2 | NPtVEVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRY |
| P09104 | T41 | Sugiyama | ENO2 | EVDLyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKG |
| P09382 | T58 | Sugiyama | LGALS1 | DsNNLCLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVF |
| P09496 | S236 | Sugiyama | CLTA | RLCDFNPKSSKQAKDVSRMRsVLIsLKQAPLVH________ |
| P09496 | S240 | Sugiyama | CLTA | FNPKSSKQAKDVSRMRsVLIsLKQAPLVH____________ |
| P09923 | T182 | Sugiyama | ALPI | VGVVTTTRVQHAsPAGtyAHtVNRNWysDADMPASARQEGC |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0DPH7 | S48 | Sugiyama | TUBA3C TUBA2 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P0DPH7 | S54 | Sugiyama | TUBA3C TUBA2 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P0DPH7 | T334 | Sugiyama | TUBA3C TUBA2 | ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| P0DPH7 | T51 | Sugiyama | TUBA3C TUBA2 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P0DPH7 | T56 | Sugiyama | TUBA3C TUBA2 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| P10412 | S55 | Sugiyama | H1-4 H1F4 HIST1H1E | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P10809 | S453 | Sugiyama | HSPD1 HSP60 | EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK |
| P11142 | S340 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN |
| P11142 | S362 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | RIPKIQKLLQDFFNGKELNKsINPDEAVAyGAAVQAAILsG |
| P11142 | S85 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | NtVFDAKRLIGRRFDDAVVQsDMKHWPFMVVNDAGRPKVQV |
| P11142 | T163 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy |
| P11142 | T226 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVNHFIAEFK |
| P11142 | T45 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPtN |
| P11142 | T64 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FtDtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQ |
| P11142 | T66 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | DtERLIGDAAKNQVAMNPtNtVFDAKRLIGRRFDDAVVQsD |
| P11142 | Y41 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P11586 | S129 | Sugiyama | MTHFD1 MTHFC MTHFD | INTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCtP |
| P11586 | T128 | Sugiyama | MTHFD1 MTHFC MTHFD | SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt |
| P11940 | T379 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | AtKPLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINP |
| P11940 | Y194 | Sugiyama | PABPC1 PAB1 PABP PABP1 PABPC2 | KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF |
| P12277 | S129 | Sugiyama | CKB CKBB | DLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPHCsRG |
| P12429 | S21 | Sugiyama | ANXA3 ANX3 | MASIWVGHRGTVRDyPDFsPsVDAEAIQKAIRGIGTDEKML |
| P13489 | T176 | Sugiyama | RNH1 PRI RNH | AASCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKD |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S38 | Sugiyama | EEF2 EF2 | NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD |
| P13639 | S587 | Sugiyama | EEF2 EF2 | CIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKAR |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | Y443 | Sugiyama | EEF2 EF2 | TGLKVRIMGPNytPGKKEDLyLKPIQRTILMMGRYVEPIED |
| P13639 | Y671 | Sugiyama | EEF2 EF2 | CFGPDGTGPNILTDITKGVQyLNEIKDSVVAGFQWATKEGA |
| P13667 | S126 | Sugiyama | PDIA4 ERP70 ERP72 | NILKDKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILKKG |
| P13667 | S379 | Sugiyama | PDIA4 ERP70 ERP72 | QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH |
| P13674 | T147 | Sugiyama | P4HA1 P4HA | QVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSFLTAEDC |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P13929 | S37 | Sugiyama | ENO3 | NPtVEVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRY |
| P13929 | T41 | Sugiyama | ENO3 | EVDLHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKG |
| P13987 | T76 | Sugiyama | CD59 MIC11 MIN1 MIN2 MIN3 MSK21 | AGLQVYNKCWKFEHCNFNDVtTRLRENELtyyCCKKDLCNF |
| P14314 | T469 | Sugiyama | PRKCSH G19P1 | WGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLCGKEt |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | T50 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | MCRLDIDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMN |
| P14618 | T80 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | tLKEMIKsGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAs |
| P14618 | T87 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | sGMNVARLNFsHGtHEyHAEtIKNVRtAtEsFAsDPILyRP |
| P14625 | S680 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | RIMKAQAYQtGKDIstNyyAsQKKTFEINPRHPLIRDMLRR |
| P14625 | Y727 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | DKTVLDLAVVLFETATLRsGyLLPDTKAYGDRIERMLRLsL |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14649 | T101 | Sugiyama | MYL6B MLC1SA | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDELKSRR |
| P15259 | T96 | Sugiyama | PGAM2 PGAMM | QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQVKIWR |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15880 | T232 | Sugiyama | RPS2 RPS4 | KLLMMAGIDDCytsARGCtAtLGNFAKATFDAISKTysyLt |
| P16402 | S56 | Sugiyama | H1-3 H1F3 HIST1H1D | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P16403 | S55 | Sugiyama | H1-2 H1F2 HIST1H1C | AsGPPVsELItKAVAASKERsGVsLAALKKALAAAGyDVEK |
| P17066 | T47 | Sugiyama | HSPA6 HSP70B' | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P17066 | Y43 | Sugiyama | HSPA6 HSP70B' | FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL |
| P17987 | S35 | Sugiyama | TCP1 CCT1 CCTA | EtIRsQNVMAAAsIANIVKssLGPVGLDKMLVDDIGDVTIT |
| P17987 | S551 | Sugiyama | TCP1 CCT1 CCTA | IKLHPESKDDKHGsyEDAVHsGALND_______________ |
| P18669 | T159 | Sugiyama | PGAM1 PGAMA CDABP0006 | DRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQIKEGK |
| P18669 | T96 | Sugiyama | PGAM1 PGAMA CDABP0006 | QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR |
| P19338 | S458 | Sugiyama | NCL | TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN |
| P20290 | S126 | Sugiyama | BTF3 NACB OK/SW-cl.8 | VNMFTNQGTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEM |
| P20290 | T133 | Sugiyama | BTF3 NACB OK/SW-cl.8 | GTVIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQ |
| P20290 | T135 | Sugiyama | BTF3 NACB OK/SW-cl.8 | VIHFNNPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLG |
| P20290 | T140 | Sugiyama | BTF3 NACB OK/SW-cl.8 | NPKVQAsLAANtFtItGHAEtKQLTEMLPsILNQLGADsLt |
| P20618 | S151 | Sugiyama | PSMB1 PSC5 | PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA |
| P20674 | T105 | Sugiyama | COX5A | EPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYPY |
| P20810 | S527 | Sugiyama | CAST | sEDFLLDALSEDFSGPQNAssLKFEDAKLAAAISEVVsQtP |
| P22090 | T141 | Sugiyama | RPS4Y1 RPS4Y PRO2646 | YKLCKVRKITVGVKGIPHLVtHDARTIRYPDPVIKVNDTVQ |
| P23246 | S283 | Sugiyama | SFPQ PSF | GPGGRsEEKIsDsEGFKANLsLLRRPGEKTyTQRCRLFVGN |
| P23434 | S153 | Sugiyama | GCSH | LVNKSCyEDGWLIKMtLsNPsELDELMsEEAyEKYIKSIEE |
| P23526 | S183 | Sugiyama | AHCY SAHH | NLyKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGI |
| P23526 | T157 | Sugiyama | AHCY SAHH | NLIHTKYPQLLPGIRGIsEEtTTGVHNLyKMMANGILKVPA |
| P23526 | T185 | Sugiyama | AHCY SAHH | yKMMANGILKVPAINVNDsVtKsKFDNLyGCRESLIDGIKR |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P23588 | S122 | Sugiyama | EIF4B | NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA |
| P24752 | S218 | Sugiyama | ACAT1 ACAT MAT | ENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPV |
| P24752 | Y214 | Sugiyama | ACAT1 ACAT MAT | GsCAENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNE |
| P26038 | S576 | Sugiyama | MSN | YKtLRQIRQGNTKQRIDEFEsM___________________ |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | S97 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | sLEELRVAGIHKKVARTIGIsVDPRRRNKstEsLQANVQRL |
| P26639 | S522 | Sugiyama | TARS1 TARS | PEKFLGDIEVWDQAEKQLENsLNEFGEKWELNsGDGAFyGP |
| P26639 | T250 | Sugiyama | TARS1 TARS | FKYNKFKCRILNEKVNtPtttVyRCGPLIDLCRGPHVRHTG |
| P26639 | T700 | Sugiyama | TARS1 TARS | EKISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAE |
| P26641 | S304 | Sugiyama | EEF1G EF1G PRO1608 | PKstFVLDEFKRKysNEDtLsVALPyFWEHFDKDGWSLWyS |
| P26641 | T302 | Sugiyama | EEF1G EF1G PRO1608 | HLPKstFVLDEFKRKysNEDtLsVALPyFWEHFDKDGWSLW |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P28715 | S382 | Sugiyama | ERCC5 ERCM2 XPG XPGC | EsENRRQARGRNAPAAVDEGsIsPRtLSAIKRALDDDEDVK |
| P29401 | S295 | Sugiyama | TKT | ysQIQsKKKILAtPPQEDAPsVDIANIRMPsLPsyKVGDKI |
| P29401 | S305 | Sugiyama | TKT | LAtPPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQAL |
| P29401 | S548 | Sugiyama | TKT | NIRVLDPFTIKPLDRKLILDsARAtKGRILTVEDHYYEGGI |
| P29401 | T342 | Sugiyama | TKT | GQALAKLGHAsDRIIALDGDtKNstFsEIFKKEHPDRFIEC |
| P29401 | T442 | Sugiyama | TKT | GEDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAA |
| P29401 | T444 | Sugiyama | TKT | DGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAANT |
| P29692 | S133 | Sugiyama | EEF1D EF1D | NVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPAEDDE |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P29692 | S64 | Sugiyama | EEF1D EF1D | sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI |
| P29692 | T129 | Sugiyama | EEF1D EF1D | EARLNVLEKssPGHRAtAPQtQHVsPMRQVEPPAKKPAtPA |
| P30040 | Y202 | Sugiyama | ERP29 C12orf8 ERP28 | KQGQDNLSSVKETQKKWAEQyLKIMGKILDQGEDFPAsEMT |
| P30041 | T95 | Sugiyama | PRDX6 AOP2 KIAA0106 | SVEDHLAWSKDINAyNCEEPtEKLPFPIIDDRNRELAILLG |
| P30043 | S198 | Sugiyama | BLVRB FLR SCAN | KHDLGHFMLRCLttDEyDGHstyPsHQyQ____________ |
| P30044 | S171 | Sugiyama | PRDX5 ACR1 SBBI10 | ADPTGAFGKEtDLLLDDsLVsIFGNRRLKRFsMVVQDGIVK |
| P30050 | T25 | Sugiyama | RPL12 | FDPNEIKVVYLRCtGGEVGAtsALAPKIGPLGLsPKKVGDD |
| P30622 | Y262 | Sugiyama | CLIP1 CYLN1 RSN | CGVELDEPLGKNDGAVAGtRyFQCQPKyGLFAPVHKVTKIG |
| P30740 | S72 | Sugiyama | SERPINB1 ELANH2 MNEI PI2 | AQLSKTFHFNTVEEVHSRFQsLNADINKRGASYILKLANRL |
| P31150 | S213 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | RTDDyLDQPCLETVNRIKLYsEsLARYGKsPYLyPLyGLGE |
| P31150 | S316 | Sugiyama | GDI1 GDIL OPHN2 RABGDIA XAP4 | QVIRIICILSHPIKNtNDANsCQIIIPQNQVNRKSDIYVCM |
| P31153 | S247 | Sugiyama | MAT2A AMS2 MATA2 | IKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLtGRKII |
| P31153 | T240 | Sugiyama | MAT2A AMS2 MATA2 | DALKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAG |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P31327 | T45 | Sugiyama | CPS1 | AHQKWKFSRPGIRLLSVKAQtAHIVLEDGtKMKGYSFGHPS |
| P31327 | Y1450 | Sugiyama | CPS1 | GsIDLVINLPNNNTKFVHDNyVIRRTAVDSGIPLLTNFQVT |
| P31942 | T17 | Sugiyama | HNRNPH3 HNRPH3 | ____MDWVMKHNGPNDASDGtVRLRGLPFGCSKEEIVQFFQ |
| P31943 | S281 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | GRDLNyCFsGMsDHRyGDGGstFQsttGHCVHMRGLPYRAt |
| P31948 | Y354 | Sugiyama | STIP1 | DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG |
| P32929 | S56 | Sugiyama | CTH | AVVPPISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVA |
| P32929 | S61 | Sugiyama | CTH | ISLSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGA |
| P32929 | S63 | Sugiyama | CTH | LSTTFKQGAPGQHsGFEysRsGNPTRNCLEKAVAALDGAKY |
| P33316 | S164 | Sugiyama | DUT | YTIPPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDV |
| P34931 | T47 | Sugiyama | HSPA1L | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPQN |
| P34931 | Y373 | Sugiyama | HSPA1L | QDYFNGRDLNKsINPDEAVAyGAAVQAAILMGDKSEKVQDL |
| P34931 | Y43 | Sugiyama | HSPA1L | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P35813 | S181 | Sugiyama | PPM1A PPPM1A | TQDHKPSNPLEKERIQNAGGsVMIQRVNGsLAVSRALGDFD |
| P36578 | S87 | Sugiyama | RPL4 RPL1 | WGtGRAVARIPRVRGGGtHRsGQGAFGNMCRGGRMFAPTKT |
| P37802 | S145 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | VQRTLMNLGGLAVARDDGLFsGDPNWFPKKSKENPRNFsDN |
| P37802 | T180 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | RNFsDNQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL_ |
| P37802 | T190 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________ |
| P37802 | T84 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | ELINALYPEGQAPVKKIQAstMAFKQMEQIsQFLQAAERYG |
| P38117 | T172 | Sugiyama | ETFB FP585 | QVTLEGDKLKVEREIDGGLEtLRLKLPAVVTADLRLNEPRy |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S549 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | IVHVSAKDKGTGREQQIVIQssGGLsKDDIENMVKNAEKYA |
| P38646 | T116 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | DGERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKD |
| P38646 | T120 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | LVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIKNV |
| P38646 | T398 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA |
| P38646 | Y118 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK |
| P39019 | S90 | Sugiyama | RPS19 | AGVGsMTKIYGGRQRNGVMPsHFsRGsKsVARRVLQALEGL |
| P39019 | T36 | Sugiyama | RPS19 | RALAAFLKKSGKLKVPEWVDtVKLAKHKELAPyDENWFytR |
| P39023 | S265 | Sugiyama | RPL3 OK/SW-cl.32 | HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY |
| P39687 | S117 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | GNKIKDLstIEPLKKLENLKsLDLFNCEVtNLNDyRENVFK |
| P39687 | T126 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | IEPLKKLENLKsLDLFNCEVtNLNDyRENVFKLLPQLtyLD |
| P40222 | S65 | Sugiyama | TXLNA TXLN | GPGsSQAPRKPEGAQARTAQsGALRDVSEELSRQLEDILST |
| P40261 | Y11 | Sugiyama | NNMT | __________MESGFTSKDTyLSHFNPRDYLEKYYKFGSRH |
| P40763 | S194 | Sugiyama | STAT3 APRF | FNyKTLKsQGDMQDLNGNNQsVTRQKMQQLEQMLTALDQMR |
| P40763 | S727 | SIGNOR | STAT3 APRF | KTKFICVtPttCsNtIDLPMsPRTLDSLMQFGNNGEGAEPS |
| P41567 | T46 | Sugiyama | EIF1 SUI1 | GTEDyIHIRIQQRNGRKtLttVQGIADDyDKKKLVKAFKKK |
| P42677 | S78 | Sugiyama | RPS27 MPS1 | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| P45985 | T261 | SIGNOR | MAP2K4 JNKK1 MEK4 MKK4 PRKMK4 SEK1 SERK1 SKK1 | GNIKLCDFGIsGQLVDsIAKtRDAGCRPyMAPERIDPSASR |
| P46060 | S24 | Sugiyama | RANGAP1 KIAA1835 SD | EDIAKLAETLAKTQVAGGQLsFKGKSLKLNTAEDAKDVIKE |
| P46060 | T60 | Sugiyama | RANGAP1 KIAA1835 SD | DVIKEIEDFDsLEALRLEGNtVGVEAARVIAKALEKKSELK |
| P46531 | T2511 | EPSD|PSP | NOTCH1 TAN1 | SSPVDNTPSHQLQVPEHPFLtPsPEsPDQWssssPHSNVSD |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46776 | T72 | Sugiyama | RPL27A | yFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAK |
| P46777 | S176 | Sugiyama | RPL5 MSTP030 | GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46782 | S75 | Sugiyama | RPS5 | RYAAKRFRKAQCPIVERLtNsMMMHGRNNGKKLMTVRIVKH |
| P46783 | T148 | Sugiyama | RPS10 | RRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ___ |
| P47712 | S727 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | VIKEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKP |
| P47756 | S192 | Sugiyama | CAPZB | TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN |
| P47756 | T186 | Sugiyama | CAPZB | HYKLTSTVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDC |
| P47914 | Y98 | Sugiyama | RPL29 | PKEVKPKIPKGVSRKLDRLAyIAHPKLGKRARARIAKGLRL |
| P48741 | T47 | Sugiyama | HSPA7 HSP70B | RVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAALNPHN |
| P48741 | Y43 | Sugiyama | HSPA7 HSP70B | FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL |
| P49321 | S662 | Sugiyama | NASP | LKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsstsGF |
| P49327 | T1999 | Sugiyama | FASN FAS | LLENQTPEFFQDVCKPKYsGtLNLDRVTREACPELDYFVVF |
| P49327 | T2215 | Sugiyama | FASN FAS | DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN |
| P49327 | T309 | Sugiyama | FASN FAS | yIEAHGtGTKVGDPQELNGItRALCAtRQEPLLIGsTKSNM |
| P49368 | T373 | Sugiyama | CCT3 CCTG TRIC5 | KKIGDEYFTFITDCKDPKACtILLRGAsKEILSEVERNLQD |
| P49368 | T459 | Sugiyama | CCT3 CCTG TRIC5 | AVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtWG |
| P49589 | S34 | Sugiyama | CARS1 CARS | VQPQWsPPAGtQPCRLHLyNsLtRNKEVFIPQDGKKVTWYC |
| P49773 | T17 | Sugiyama | HINT1 HINT PKCI1 PRKCNH1 | ____MADEIAKAQVARPGGDtIFGKIIRKEIPAKIIFEDDR |
| P49792 | T1756 | Sugiyama | RANBP2 NUP358 | RNEASATKCIACQCPSKQNQtTAIstPAssEIsKAPKsGFE |
| P50395 | S213 | Sugiyama | GDI2 RABGDIB | RtDDyLDQPCyEtINRIKLYsEsLARYGKsPYLyPLyGLGE |
| P50395 | S316 | Sugiyama | GDI2 RABGDIB | QVIRVICILSHPIKNtNDANsCQIIIPQNQVNRKSDIyVCM |
| P50395 | T205 | Sugiyama | GDI2 RABGDIB | TGHALALYRtDDyLDQPCyEtINRIKLYsEsLARYGKsPYL |
| P50454 | T314 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | MGKMQKKAVAISLPKGVVEVtHDLQKHLAGLGLtEAIDKNK |
| P50990 | T398 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | RGstDNLMDDIERAVDDGVNtFKVLTRDKRLVPGGGAtEIE |
| P51149 | T168 | Sugiyama | RAB7A RAB7 | NIPyFEtSAKEAINVEQAFQtIARNALKQETEVELyNEFPE |
| P51858 | S40 | Sugiyama | HDGF HMG1L2 | MKGyPHWPARIDEMPEAAVKstANKYQVFFFGTHETAFLGP |
| P51858 | T94 | Sugiyama | HDGF HMG1L2 | GKPNKRKGFsEGLWEIENNPtVKASGYQSsQKKsCVEEPEP |
| P52272 | T68 | Sugiyama | HNRNPM HNRPM NAGR1 | KRKEKNIKRGGNRFEPyANPtKRYRAFITNIPFDVKWQsLK |
| P52564 | T211 | SIGNOR | MAP2K6 MEK6 MKK6 PRKMK6 SKK3 | GQVKMCDFGISGyLVDsVAKtIDAGCKPyMAPERINPELNQ |
| P52907 | S123 | Sugiyama | CAPZA1 | KEAsDPQPEEADGGLKsWREsCDsALRAYVKDHYSNGFCTV |
| P52907 | S215 | Sugiyama | CAPZA1 | QVHYYEDGNVQLVSHKDVQDsLtVsNEAQtAKEFIKIIENA |
| P52948 | T687 | Sugiyama | NUP98 ADAR2 | IPQtPEsAGNKHsNsNsVDDtIVALNMRAALRNGLEGssEE |
| P53396 | S656 | Sugiyama | ACLY | IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR |
| P54652 | T229 | Sugiyama | HSPA2 | DVSILTIEDGIFEVKstAGDtHLGGEDFDNRMVSHLAEEFK |
| P54652 | T46 | Sugiyama | HSPA2 | KVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAMNPTN |
| P54652 | Y42 | Sugiyama | HSPA2 | FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM |
| P55036 | S358 | Sugiyama | PSMD4 MCB1 | VLENLPGVDPNNEAIRNAMGsLAsQATKDGKKDKKEEDKK_ |
| P55036 | T264 | Sugiyama | PSMD4 MCB1 | AEAGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEE |
| P55060 | S931 | Sugiyama | CSE1L CAS XPO2 | KKEHDPVGQMVNNPKIHLAQsLHKLSTACPGRVPSMVSTSL |
| P55060 | T341 | Sugiyama | CSE1L CAS XPO2 | LASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEA |
| P55209 | S69 | Sugiyama | NAP1L1 NRP | LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA |
| P55854 | S27 | Sugiyama | SUMO3 SMT3A SMT3H1 | KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC |
| P56192 | S127 | Sugiyama | MARS1 MARS | GKKGEDVLGSVRRALTHIDHsLSRQNCPFLAGETESLADIV |
| P56192 | S812 | Sugiyama | MARS1 MARS | GHQIGTVSPLFQKLENDQIEsLRQRFGGGQAKtsPKPAVVE |
| P56537 | T91 | Sugiyama | EIF6 EIF3A ITGB4BP OK/SW-cl.27 | LVPNNTTDQELQHIRNSLPDtVQIRRVEERLSALGNVTTCN |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | S97 | Sugiyama | TPI1 TPI | GEIsPGMIKDCGAtWVVLGHsERRHVFGEsDELIGQKVAHA |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60174 | Y209 | Sugiyama | TPI1 TPI | LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60660 | T103 | Sugiyama | MYL6 | QGtyEDyVEGLRVFDKEGNGtVMGAEIRHVLVtLGEKMTEE |
| P60660 | T44 | Sugiyama | MYL6 | DGKILysQCGDVMRALGQNPtNAEVLKVLGNPKsDEMNVKV |
| P60709 | S323 | Sugiyama | ACTB | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | T106 | Sugiyama | ACTB | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P60709 | T201 | Sugiyama | ACTB | AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL |
| P60709 | T324 | Sugiyama | ACTB | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P61201 | S221 | Sugiyama | COPS2 CSN2 TRIP15 | EIQMYTAQKNNKKLKALYEQsLHIKSAIPHPLIMGVIRECG |
| P61247 | S263 | Sugiyama | RPS3A FTE1 MFTL | GDEtGAKVERADGyEPPVQEsV___________________ |
| P61289 | T99 | Sugiyama | PSME3 | LDGPTYKKRRLDECEEAFQGtKVFVMPNGMLKSNQQLVDII |
| P61353 | T94 | Sugiyama | RPL27 | VyNyNHLMPtRysVDIPLDKtVVNKDVFRDPALKRKARREA |
| P61604 | S64 | Sugiyama | HSPE1 | AtVVAVGsGsKGKGGEIQPVsVKVGDKVLLPEyGGtKVVLD |
| P61604 | T45 | Sugiyama | HSPE1 | TVTKGGIMLPEKSQGKVLQAtVVAVGsGsKGKGGEIQPVsV |
| P61769 | S75 | Sugiyama | B2M CDABP0092 HDCMA22P | IEVDLLKNGERIEKVEHsDLsFsKDWSFYLLYYTEFTPTEK |
| P61769 | S77 | Sugiyama | B2M CDABP0092 HDCMA22P | VDLLKNGERIEKVEHsDLsFsKDWSFYLLYYTEFTPTEKDE |
| P61956 | S28 | Sugiyama | SUMO2 SMT3B SMT3H2 | EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61981 | T31 | Sugiyama | YWHAG | ARLAEQAERyDDMAAAMKNVtELNEPLsNEERNLLsVAyKN |
| P62191 | T369 | Sugiyama | PSMC1 | RKIEFPLPDEKTKKRIFQIHtSRMTLADDVTLDDLIMAKDD |
| P62191 | T56 | Sugiyama | PSMC1 | KKKKTKGPDAASKLPLVtPHtQCRLKLLKLERIKDYLLMEE |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S117 | Sugiyama | YWHAE | CCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAEFAt |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | T114 | Sugiyama | YWHAE | KLICCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAE |
| P62263 | S139 | Sugiyama | RPS14 PRO2640 | LARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL________ |
| P62273 | S9 | Sugiyama | RPS29 | ____________MGHQQLyWsHPRKFGQGSRSCRVCSNRHG |
| P62273 | Y7 | Sugiyama | RPS29 | ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR |
| P62277 | S14 | Sugiyama | RPS13 | _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK |
| P62280 | S67 | Sugiyama | RPS11 | PKEAIEGtyIDKKCPFTGNVsIRGRILsGVVTKMKMQRTIV |
| P62280 | T15 | Sugiyama | RPS11 | ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR |
| P62280 | T54 | Sugiyama | RPS11 | PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs |
| P62316 | T40 | Sugiyama | SNRPD2 SNRPD1 | EEEEFNtGPLsVLtQsVKNNtQVLINCRNNKKLLGRVKAFD |
| P62701 | T141 | Sugiyama | RPS4X CCG2 RPS4 SCAR | YKLCKVRKIFVGTKGIPHLVtHDARTIRYPDPLIKVNDtIQ |
| P62701 | T159 | Sugiyama | RPS4X CCG2 RPS4 SCAR | LVtHDARTIRYPDPLIKVNDtIQIDLEtGKITDFIKFDtGN |
| P62736 | S325 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | T326 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P62826 | T66 | Sugiyama | RAN ARA24 OK/SW-cl.81 | EVHPLVFHTNRGPIKFNVWDtAGQEKFGGLRDGYYIQAQCA |
| P62857 | S41 | Sugiyama | RPS28 | tGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLLEs |
| P62899 | T26 | Sugiyama | RPL31 | KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62942 | S68 | Sugiyama | FKBP1A FKBP1 FKBP12 | KFMLGKQEVIRGWEEGVAQMsVGQRAKLTISPDYAYGATGH |
| P62942 | T22 | Sugiyama | FKBP1A FKBP1 FKBP12 | GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD |
| P62942 | T7 | Sugiyama | FKBP1A FKBP1 FKBP12 | ______________MGVQVEtIsPGDGRtFPKRGQtCVVHy |
| P62979 | S134 | Sugiyama | RPS27A UBA80 UBCEP1 | IsRLRRECPsDECGAGVFMAsHFDRHyCGKCCLtyCFNKPE |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63167 | T26 | Sugiyama | DYNLL1 DLC1 DNCL1 DNCLC1 HDLC1 | AVIKNADMsEEMQQDsVECAtQALEKYNIEKDIAAHIKKEF |
| P63173 | T14 | Sugiyama | RPL38 | _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF |
| P63220 | S31 | Sugiyama | RPS21 | LYVPRKCSASNRIIGAKDHAsIQMNVAEVDKVTGRFNGQFK |
| P63220 | S68 | Sugiyama | RPS21 | GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____ |
| P63261 | S323 | Sugiyama | ACTG1 ACTG | ttMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGG |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | T106 | Sugiyama | ACTG1 ACTG | WHHtFyNELRVAPEEHPVLLtEAPLNPKANREKMTQIMFET |
| P63261 | T201 | Sugiyama | ACTG1 ACTG | AGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyVAL |
| P63261 | T324 | Sugiyama | ACTG1 ACTG | tMyPGIADRMQKEItALAPstMKIKIIAPPERKYsVWIGGs |
| P63267 | S324 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | T325 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P67809 | T108 | Sugiyama | YBX1 NSEP1 YB1 | QtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEAANVtGP |
| P67809 | Y72 | Sugiyama | YBX1 NSEP1 YB1 | KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK |
| P68032 | S325 | Sugiyama | ACTC1 ACTC | tTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | T326 | Sugiyama | ACTC1 ACTC | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68104 | T261 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA |
| P68104 | T432 | Sugiyama | EEF1A1 EEF1A EF1A LENG7 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| P68133 | S325 | Sugiyama | ACTA1 ACTA | TTMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGG |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | T326 | Sugiyama | ACTA1 ACTA | TMYPGIADRMQKEItALAPstMKIKIIAPPERKYSVWIGGS |
| P68363 | S48 | Sugiyama | TUBA1B | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| P68363 | S54 | Sugiyama | TUBA1B | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P68363 | T334 | Sugiyama | TUBA1B | ACCLLyRGDVVPKDVNAAIAtIKtKRsIQFVDWCPTGFKVG |
| P68363 | T51 | Sugiyama | TUBA1B | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| P68363 | T56 | Sugiyama | TUBA1B | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| P68363 | T73 | Sugiyama | TUBA1B | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| P68363 | T80 | Sugiyama | TUBA1B | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| P68431 | T46 | Sugiyama | H3C1 H3FA HIST1H3A; H3C2 H3FL HIST1H3B; H3C3 H3FC HIST1H3C; H3C4 H3FB HIST1H3D; H3C6 H3FD HIST1H3E; H3C7 H3FI HIST1H3F; H3C8 H3FH HIST1H3G; H3C10 H3FK HIST1H3H; H3C11 H3FF HIST1H3I; H3C12 H3FJ HIST1H3J | ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| P78406 | T256 | Sugiyama | RAE1 MRNP41 | IEGRVAIHYINPPNPAKDNFtFKCHRSNGTNTSAPQDIyAV |
| P78417 | S23 | Sugiyama | GSTO1 GSTTLP28 | GESARsLGKGsAPPGPVPEGsIRIySMRFCPFAERTRLVLK |
| P78527 | T2649 | Sugiyama | PRKDC HYRC HYRC1 | WPVAGQIRAtQQQHDFtLtQtADGRssFDWLTGsstDPLVD |
| P84098 | S12 | Sugiyama | RPL19 | _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI |
| P84098 | S122 | Sugiyama | RPL19 | LRRLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHI |
| P84098 | T29 | Sugiyama | RPL19 | RLAssVLRCGKKKVWLDPNEtNEIANANsRQQIRKLIKDGL |
| P84098 | Y124 | Sugiyama | RPL19 | RLLRRYRESKKIDRHMyHsLyLKVKGNVFKNKRILMEHIHK |
| P84243 | T46 | Sugiyama | H3-3A H3.3A H3F3 H3F3A PP781; H3-3B H3.3B H3F3B | ARKsAPsTGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| Q00341 | T729 | Sugiyama | HDLBP HBP VGL | VEKAKKQLLHLAEEKQTKSFtVDIRAKPEYHKFLIGKGGGK |
| Q00839 | Y260 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01105 | S161 | Sugiyama | SET | FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK |
| Q01105 | S166 | Sugiyama | SET | yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q01130 | Y44 | Sugiyama | SRSF2 SFRS2 | RtsPDtLRRVFEKYGRVGDVyIPRDRYTKESRGFAFVRFHD |
| Q02750 | S218 | SIGNOR|ELM | MAP2K1 MEK1 PRKMK1 | VNSRGEIKLCDFGVsGQLIDsMANsFVGtRSYMsPERLQGT |
| Q02750 | S222 | SIGNOR|ELM | MAP2K1 MEK1 PRKMK1 | GEIKLCDFGVsGQLIDsMANsFVGtRSYMsPERLQGTHYSV |
| Q02790 | T278 | Sugiyama | FKBP4 FKBP52 | sWEMNsEEKLEQSTIVKERGtVYFKEGKYKQALLQYKKIVS |
| Q02818 | S193 | Sugiyama | NUCB1 NUC | HEEFKRyEMLKEHERRRyLEsLGEEQRKEAERKLEEQQRRH |
| Q02818 | T148 | Sugiyama | NUCB1 NUC | QVDHLNLLKQFEHLDPQNQHtFEARDLELLIQTATRDLAQY |
| Q02878 | S255 | Sugiyama | RPL6 TXREB1 | tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF |
| Q04637 | T1119 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | GGSGAKPSDAAsEAARPAtstLNRFsALQQAVPtEsTDNRR |
| Q05639 | T261 | Sugiyama | EEF1A2 EEF1AL STN | PTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRPGMVVTFA |
| Q05639 | T432 | Sugiyama | EEF1A2 EEF1AL STN | VESFSQYPPLGRFAVRDMRQtVAVGVIKNVEKKSGGAGKVT |
| Q05682 | S131 | Sugiyama | CALD1 CAD CDM | LQEALERQKEFDPtItDAsLsLPsRRMQNDTAENETTEKEE |
| Q06830 | S152 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV |
| Q06830 | S30 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | HPAPNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTF |
| Q06830 | T156 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | KGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEVCPAG |
| Q06830 | T183 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | FQFtDKHGEVCPAGWKPGsDtIKPDVQKSKEyFSKQK____ |
| Q07020 | T136 | Sugiyama | RPL18 | AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP |
| Q07666 | S29 | Sugiyama | KHDRBS1 SAM68 | ARMsRssGRsGsMDPsGAHPsVRQtPsRQPPLPHRSRGGGG |
| Q12846 | S117 | Sugiyama | STX4 STX4A | IRLQLKAIEPQKEEADENyNsVNtRMRKTQHGVLSQQFVEL |
| Q13153 | T109 | Sugiyama | PAK1 | FDAVTGEFTGMPEQWARLLQtsNITKsEQKKNPQAVLDVLE |
| Q13158 | S194 | SIGNOR|EPSD|PSP | FADD MORT1 GIG3 | ADLVQEVQQARDLQNRsGAMsPMsWNsDAsTSEAS______ |
| Q13162 | S73 | Sugiyama | PRDX4 | FyAGGQVyPGEAsRVsVADHsLHLSKAKISKPAPYWEGTAV |
| Q13177 | T108 | Sugiyama | PAK2 | FDAVTGEFTGMPEQWARLLQtsNItKLEQKKNPQAVLDVLK |
| Q13233 | S1281 | Sugiyama | MAP3K1 MAPKKK1 MEKK MEKK1 | QDVGTGTLMAVKQVTYVRNTsSEQEEVVEALREEIRMMSHL |
| Q13233 | S1358 | Sugiyama | MAP3K1 MAPKKK1 MEKK MEKK1 | YGAFKESVVINYTEQLLRGLsyLHENQIIHRDVKGANLLID |
| Q13233 | S1379 | Sugiyama | MAP3K1 MAPKKK1 MEKK MEKK1 | yLHENQIIHRDVKGANLLIDsTGQRLRIADFGAAARLASKG |
| Q13233 | T1400 | Sugiyama | MAP3K1 MAPKKK1 MEKK MEKK1 | TGQRLRIADFGAAARLASKGtGAGEFQGQLLGtIAFMAPEV |
| Q13233 | T1412 | Sugiyama | MAP3K1 MAPKKK1 MEKK MEKK1 | AARLASKGtGAGEFQGQLLGtIAFMAPEVLRGQQYGRSCDV |
| Q13233 | Y1359 | Sugiyama | MAP3K1 MAPKKK1 MEKK MEKK1 | GAFKESVVINYTEQLLRGLsyLHENQIIHRDVKGANLLIDs |
| Q13242 | T177 | Sugiyama | SRSF9 SFRS9 SRP30C | DMEYALRKLDDTKFRsHEGEtsYIRVYPERstsYGYsRsRS |
| Q13283 | T71 | Sugiyama | G3BP1 G3BP | PADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLNDGVV |
| Q13310 | Y194 | Sugiyama | PABPC4 APP1 PABP4 | KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF |
| Q13442 | S178 | Sugiyama | PDAP1 HASPP28 | EEERKAKDDATLsGKRMQsLsLNK_________________ |
| Q13561 | S391 | Sugiyama | DCTN2 DCTN50 | LTQVQTTMRENLATVEGNFAsIDERMKKLGK__________ |
| Q13561 | T315 | Sugiyama | DCTN2 DCTN50 | KHKASVEDADTQSKVHQLyEtIQRWsPIASTLPELVQRLVT |
| Q13765 | S117 | Sugiyama | NACA HSD48 | RKSKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQL |
| Q14152 | S215 | Sugiyama | EIF3A EIF3S10 KIAA0139 | RKLCDNLRMHLsQIQRHHNQstAINLNNPESQsMHLETRLV |
| Q14152 | S584 | Sugiyama | EIF3A EIF3S10 KIAA0139 | EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV |
| Q14192 | T234 | Sugiyama | FHL2 DRAL SLIM3 | CDLyAKKCAGCTNPISGLGGtKyIsFEERQWHNDCFNCKKC |
| Q14247 | S432 | Sugiyama | CTTN EMS1 | EERLPssPVyEDAAsFKAELsyRGPVsGtEPEPVysMEAAD |
| Q14247 | Y433 | Sugiyama | CTTN EMS1 | ERLPssPVyEDAAsFKAELsyRGPVsGtEPEPVysMEAADy |
| Q14444 | T103 | Sugiyama | CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 | NKGERLNQDQLDAVsKyQEVtNNLEFAKELQRsFMALsQDI |
| Q14566 | T195 | Sugiyama | MCM6 | TQPNICRNPVCANRRRFLLDtNKSRFVDFQKVRIQETQAEL |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14568 | T109 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | LTIVDTGIGMTKADLINNLGtIAKSGtKAFMEALQAGADIS |
| Q14677 | T215 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | FPFSDKLGELsDKIGstIDDtIsKFRRKDREDsPERCsDsD |
| Q15056 | S110 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | DEVDsLKEALtyDGALLGDRsLRVDIAEGRKQDKGGFGFRK |
| Q15056 | S69 | Sugiyama | EIF4H KIAA0038 WBSCR1 WSCR1 | LPFNTVQGDIDAIFKDLsIRsVRLVRDKDTDKFKGFCyVEF |
| Q15181 | Y90 | Sugiyama | PPA1 IOPPP PP | KQDVKKGKLRyVANLFPyKGyIWNyGAIPQtWEDPGHNDKH |
| Q15185 | S72 | Sugiyama | PTGES3 P23 TEBP | EIDLFHCIDPNDsKHKRtDRsILCCLRKGEsGQsWPRLTKE |
| Q15185 | S85 | Sugiyama | PTGES3 P23 TEBP | KHKRtDRsILCCLRKGEsGQsWPRLTKERAKLNWLsVDFNN |
| Q15293 | Y115 | Sugiyama | RCN1 RCN | GDGFVttEELKtWIKRVQKRyIFDNVAKVWKDYDRDKDDKI |
| Q15369 | T41 | Sugiyama | ELOC TCEB1 | LISSDGHEFIVKREHALtsGtIKAMLSGPGQFAENETNEVN |
| Q15459 | S508 | Sugiyama | SF3A1 SAP114 | IGEEEIQKPEEKVTWDGHsGsMARTQQAAQANITLQEQIEA |
| Q15813 | T56 | Sugiyama | TBCE | WLGVEWDNPERGKHDGSHEGtVyFKCRHPTGGSFIRPNKVN |
| Q16401 | S98 | Sugiyama | PSMD5 KIAA0072 | VHVARNLRVDLQRGLIHPDDsVKILTLSQIGRIVENSDAVT |
| Q16576 | T10 | Sugiyama | RBBP7 RBAP46 | ___________MAsKEMFEDtVEERVINEEYKIWKKNTPFL |
| Q16658 | T239 | Sugiyama | FSCN1 FAN1 HSN SNL | GKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELFALEQs |
| Q16695 | T46 | Sugiyama | H3-4 H3FT HIST3H3 | ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| Q16881 | T454 | Sugiyama | TXNRD1 GRIM12 KDRF | YNTVMLAIGRDACTRKIGLEtVGVKINEKTGKIPVTDEEQT |
| Q4G0X9 | S553 | Sugiyama | CCDC40 KIAA1640 | EIEAYKKSIMKEEEKNEKLAsILNRTETEATLLQKLTTQCL |
| Q58FF7 | S370 | Sugiyama | HSP90AB3P HSP90BC | KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI |
| Q58FF7 | T489 | Sugiyama | HSP90AB3P HSP90BC | YGWTANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIME |
| Q58FF7 | Y492 | Sugiyama | HSP90AB3P HSP90BC | TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR |
| Q58FF8 | S258 | Sugiyama | HSP90AB2P HSP90BB | LAVRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQ |
| Q58FF8 | T104 | Sugiyama | HSP90AB2P HSP90BB | LTLVDTGIGMTKADLINNLGtIAKFQDQTEYLEEMQVKEVV |
| Q58FG0 | Y177 | Sugiyama | HSP90AA5P HSP90AE | GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ |
| Q5JRX3 | S997 | Sugiyama | PITRM1 KIAA1104 MP1 PREP | FLYGLSDEMKQAHREQLFAVsHDKLLAVSDRYLGTGKSTHG |
| Q5T6C5 | S664 | Sugiyama | ATXN7L2 | QLENRGAAGHPAKALPTNCLsEEEVAKKRKNLATYCRPVKA |
| Q5VTE0 | T261 | Sugiyama | EEF1A1P5 EEF1AL3 | PTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKPGMVVtFA |
| Q5VTE0 | T432 | Sugiyama | EEF1A1P5 EEF1AL3 | VEsFSDyPPLGRFAVRDMRQtVAVGVIKAVDKKAAGAGKVT |
| Q6EEV6 | S28 | Sugiyama | SUMO4 SMT3H4 | EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC |
| Q6NXT2 | T45 | Sugiyama | H3-5 H3F3C | AARKSTPSTCGVKPHRyRPGtVALREIRRYQKstELLIRKL |
| Q6PEY2 | S48 | Sugiyama | TUBA3E | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q6PEY2 | S54 | Sugiyama | TUBA3E | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q6PEY2 | T334 | Sugiyama | TUBA3E | ACCMLYRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q6PEY2 | T51 | Sugiyama | TUBA3E | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q6PEY2 | T56 | Sugiyama | TUBA3E | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVVD |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZMR3 | S167 | Sugiyama | LDHAL6A LDHL2 | AWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIHSESCHG |
| Q71DI3 | T46 | Sugiyama | H3C15 HIST2H3A; H3C14 H3F2 H3FM HIST2H3C; H3C13 HIST2H3D | ARKsAPATGGVKKPHRyRPGtVALREIRRYQKstELLIRKL |
| Q71U36 | S48 | Sugiyama | TUBA1A TUBA3 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q71U36 | S54 | Sugiyama | TUBA1A TUBA3 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q71U36 | T334 | Sugiyama | TUBA1A TUBA3 | ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q71U36 | T51 | Sugiyama | TUBA1A TUBA3 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q71U36 | T56 | Sugiyama | TUBA1A TUBA3 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q71U36 | T73 | Sugiyama | TUBA1A TUBA3 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q71U36 | T80 | Sugiyama | TUBA1A TUBA3 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q71UM5 | S78 | Sugiyama | RPS27L | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| Q86U42 | S235 | Sugiyama | PABPN1 PAB2 PABP2 | FAyIEFSDKEsVRTSLALDEsLFRGRQIKVIPKRTNRPGIS |
| Q8N0Y7 | T96 | Sugiyama | PGAM4 PGAM3 | QMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQVKIWR |
| Q8NBS9 | S255 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | EHSETVKIGKVDCtQHyELCsGNQVRGyPtLLWFRDGKKVD |
| Q8NBS9 | S285 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | LLWFRDGKKVDQYKGKRDLEsLREyVEsQLQRTETGATETV |
| Q8NHW3 | S14 | EPSD|PSP | MAFA | _______MAAELAMGAELPSsPLAIEYVNDFDLMKFEVKKE |
| Q8NHW3 | S65 | EPSD|PSP | MAFA | LPPGsLSStPLStPCSsVPSsPSFCAPSPGTGGGGGAGGGG |
| Q8TAM6 | S280 | Sugiyama | ERMN KIAA1189 | TISYRKIRKGNTKQRIDEFEsMMHL________________ |
| Q8TD47 | T141 | Sugiyama | RPS4Y2 RPS4Y2P | YKLCKVRKITVGTKGIPHLVtHDARTIRYPDPLIKVNDTVQ |
| Q8WWM7 | S273 | Sugiyama | ATXN2L A2D A2LG A2LP A2RP | PNEMFKFNEENyGVKTtyDssLssytVPLEKDNsEEFRQRE |
| Q92598 | T63 | Sugiyama | HSPH1 HSP105 HSP110 KIAA0201 | SKNRTIGVAAKNQQITHANNtVsNFKRFHGRAFNDPFIQKE |
| Q92688 | S117 | Sugiyama | ANP32B APRIL PHAPI2 | GNKLKDIstLEPLKKLECLKsLDLFNCEVtNLNDyREsVFK |
| Q92973 | T40 | Sugiyama | TNPO1 KPNB2 MIP1 TRN | LQQILQLLKEsQsPDTtIQRtVQQKLEQLNQYPDFNNYLIF |
| Q96HC4 | S76 | Sugiyama | PDLIM5 ENH L9 | INAQGMTHLEAQNKIKGCTGsLNMtLQRAsAAPKPEPVPVQ |
| Q96HE7 | S143 | Sugiyama | ERO1A ERO1L UNQ434/PRO865 | EANNLIEECEQAERLGAVDEsLsEEtQKAVLQWTKHDDSSD |
| Q96QK1 | T773 | Sugiyama | VPS35 MEM3 TCCCTA00141 | DLPNLEssEEtEQINKHFHNtLEHLRLRREsPEsEGPIyEG |
| Q96SU4 | T673 | Sugiyama | OSBPL9 ORP9 OSBP4 | KVRKLEDQNEYESRSLWKDVtFNLKIRDIDAATEAKHRLEE |
| Q99426 | T120 | Sugiyama | TBCB CG22 CKAP1 | DVSRVEKytIsQEAyDQRQDtVRSFLKRsKLGRyNEEERAQ |
| Q99497 | S57 | Sugiyama | PARK7 | GLAGKDPVQCsRDVVICPDAsLEDAKKEGPyDVVVLPGGNL |
| Q99613 | S639 | Sugiyama | EIF3C EIF3S8 | CAFRQGLTKDAHNALLDIQssGRAKELLGQGLLLRSLQERN |
| Q99613 | S754 | Sugiyama | EIF3C EIF3S8 | REHVVAASKAMKMGDWKTCHsFIINEKMNGKVWDLFPEADK |
| Q99613 | T880 | Sugiyama | EIF3C EIF3S8 | AEKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMR |
| Q99832 | T351 | Sugiyama | CCT7 CCTH NIP7-1 | QtSVNALSADVLGRCQVFEEtQIGGERyNFFtGCPKAKTCt |
| Q9BQE3 | S48 | Sugiyama | TUBA1C TUBA6 | HGIQPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFV |
| Q9BQE3 | S54 | Sugiyama | TUBA1C TUBA6 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q9BQE3 | T334 | Sugiyama | TUBA1C TUBA6 | ACCLLyRGDVVPKDVNAAIAtIKtKRTIQFVDWCPTGFKVG |
| Q9BQE3 | T51 | Sugiyama | TUBA1C TUBA6 | QPDGQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLE |
| Q9BQE3 | T56 | Sugiyama | TUBA1C TUBA6 | MPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtVID |
| Q9BQE3 | T73 | Sugiyama | TUBA1C TUBA6 | FsEtGAGKHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLI |
| Q9BQE3 | T80 | Sugiyama | TUBA1C TUBA6 | KHVPRAVFVDLEPtVIDEVRtGtyRQLFHPEQLItGKEDAA |
| Q9BS26 | T155 | Sugiyama | ERP44 KIAA0573 TXNDC4 UNQ532/PRO1075 | yIRQQKSDPIQEIRDLAEIttLDRSKRNIIGYFEQKDSDNy |
| Q9BUJ2 | T113 | Sugiyama | HNRNPUL1 E1BAP5 HNRPUL1 | SGPDGHYAMDNITRQNQFyDtQVIKQENESGyERRPLEMEQ |
| Q9BWD1 | S208 | Sugiyama | ACAT2 ACTL | RTENAQKAGHFDKEIVPVLVstRKGLIEVKtDEFPRHGsNI |
| Q9BXP5 | T705 | Sugiyama | SRRT ARS2 ASR2 | AQKMGRKDPEQEVEKFVtsNtQELGKDKWLCPLsGKKFKGP |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9C005 | S50 | Sugiyama | DPY30 | IVENEKINAEKSSKQKVDLQsLPTRAYLDQTVVPILLQGLA |
| Q9GZT8 | T176 | Sugiyama | NIF3L1 ALS2CR1 MDS015 My018 | SKAPNyPTEGNHRVEFNVNytQDLDKVMSAVKGIDGVsVTs |
| Q9H173 | T123 | Sugiyama | SIL1 UNQ545/PRO836 | KLQYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAE |
| Q9H173 | T125 | Sugiyama | SIL1 UNQ545/PRO836 | QYEDKFRNNLKGKRLDINtNtytsQDLKSALAKFKEGAEME |
| Q9H788 | S124 | Sugiyama | SH2D4A PPP1R38 SH2A | LKAEQEAEEPRKTHsEEFTNsLKTKsQyHDLQAPDNQQtKD |
| Q9HB07 | T193 | Sugiyama | MYG1 C12orf10 | DAVDNGISQWAEGEPRyALttTLsARVARLNPTWNHPDQDT |
| Q9NQ39 | T159 | Sugiyama | RPS10P5 RPS10L | RRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ___ |
| Q9NR30 | S706 | Sugiyama | DDX21 | PTASVTEIQEKWHDSRRWQLsVATEQPELEGPREGYGGFRG |
| Q9NSE4 | T1000 | Sugiyama | IARS2 | MPTTKEKCPRCWKYTAESSDtLCPRCAEVVSGK________ |
| Q9NY33 | S190 | Sugiyama | DPP3 | TYFSGNCTMEDAKLAQDFLDsQNLsAyNtRLFKEVDGEGKP |
| Q9P0J1 | T494 | Sugiyama | PDP1 PDP PPM2C | EDQNAATHLIRHAVGNNEFGtVDHERLSKMLSLPEELARMY |
| Q9P2B2 | T497 | Sugiyama | PTGFRN CD9P1 EWIF FPRP KIAA1436 | ERSKQRAQDGDFIFSKEHTDtFNFRIQRTTEEDRGNyyCVV |
| Q9UBR2 | S78 | Sugiyama | CTSZ | SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST |
| Q9UI15 | T190 | Sugiyama | TAGLN3 NP25 | GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________ |
| Q9UII2 | S39 | Sugiyama | ATP5IF1 ATPI ATPIF1 | TMQARGFGsDQSENVDRGAGsIREAGGAFGKREQAEEERyF |
| Q9UPQ0 | S585 | Sugiyama | LIMCH1 KIAA1102 | ETVHREEEKERECPTVAPAHsLtKSQMFEGVARVHGsPLEL |
| Q9UPQ0 | T587 | Sugiyama | LIMCH1 KIAA1102 | VHREEEKERECPTVAPAHsLtKSQMFEGVARVHGsPLELKQ |
| Q9UQ80 | T200 | Sugiyama | PA2G4 EBP1 | TPIEGMLSHQLKQHVIDGEKtIIQNPTDQQKKDHEKAEFEV |
| Q9Y262 | T44 | Sugiyama | EIF3L EIF3EIP EIF3S6IP HSPC021 HSPC025 MSTP005 | DMHTGDPKQDLAyERQyEQQtyQVIPEVIKNFIQYFHKTVS |
| Q9Y265 | S29 | Sugiyama | RUVBL1 INO80H NMP238 TIP49 TIP49A | TTKTQRIAsHSHVKGLGLDEsGLAKQAASGLVGQENAREAC |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2B0 | T132 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | NGEssELDLQGIRIDsDISGtLKFACEsIVEEyEDELIEFF |
| Q9Y2B0 | T79 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | NPDGsQsVVEVPyARsEAHLtELLEEICDRMKEyGEQIDPs |
| Q9Y2T7 | T143 | Sugiyama | YBX2 CSDA3 MSY2 | QtAIKRNNPRKFLRsVGDGEtVEFDVVEGEKGAEATNVTGP |
| Q9Y2T7 | Y107 | Sugiyama | YBX2 CSDA3 MSY2 | KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK |
| Q9Y3F4 | T109 | Sugiyama | STRAP MAWD UNRIP | VSGDELMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDL |
| Q9Y450 | S65 | Sugiyama | HBS1L HBS1 KIAA1038 | RDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCL |
| Q9Y450 | S67 | Sugiyama | HBS1L HBS1 KIAA1038 | KPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCLDH |
| Q9Y5A9 | S394 | Sugiyama | YTHDF2 HGRG8 | SQAGSGStPSEPHPVLEKLRsINNYNPKDFDWNLKHGRVFI |
| Q9Y5L4 | S57 | Sugiyama | TIMM13 TIM13B TIMM13A TIMM13B | ELLQRMTDKCFRKCIGKPGGsLDNSEQKCIAMCMDRyMDAW |
| Q9Y5X1 | S116 | Sugiyama | SNX9 SH3PX1 SH3PXD3A | SNNHQVGSGNDPWSAWSASKsGNWESsEGWGAQPEGAGAQR |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Nuclear Receptor transcription pathway | R-HSA-383280 | 7.040401e-09 | 8.152 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.698587e-08 | 7.770 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 8.656835e-08 | 7.063 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.974780e-07 | 6.704 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 2.641325e-07 | 6.578 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 7.982758e-07 | 6.098 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 7.936637e-07 | 6.100 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 9.312672e-07 | 6.031 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.083945e-06 | 5.965 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.192320e-06 | 5.924 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.396465e-06 | 5.855 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.778227e-06 | 5.750 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 3.388664e-06 | 5.470 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 4.278019e-06 | 5.369 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 7.440653e-06 | 5.128 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 9.629772e-06 | 5.016 | 0 | 0 |
| Kinesins | R-HSA-983189 | 1.474050e-05 | 4.831 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 1.680873e-05 | 4.774 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.985205e-05 | 4.702 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 2.155424e-05 | 4.666 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.133896e-05 | 4.504 | 0 | 0 |
| M Phase | R-HSA-68886 | 3.061095e-05 | 4.514 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 2.943363e-05 | 4.531 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 3.164916e-05 | 4.500 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 3.511240e-05 | 4.455 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 3.635764e-05 | 4.439 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 4.648209e-05 | 4.333 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 4.507203e-05 | 4.346 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 4.906945e-05 | 4.309 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.841061e-05 | 4.315 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 5.574355e-05 | 4.254 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 7.226757e-05 | 4.141 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 7.697143e-05 | 4.114 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 8.868090e-05 | 4.052 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.073962e-04 | 3.969 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.207189e-04 | 3.918 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 1.444355e-04 | 3.840 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.598729e-04 | 3.796 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.603176e-04 | 3.795 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 1.812213e-04 | 3.742 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 1.813067e-04 | 3.742 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.824311e-04 | 3.739 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.783955e-04 | 3.749 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.840342e-04 | 3.735 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 1.887925e-04 | 3.724 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 2.052038e-04 | 3.688 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.116140e-04 | 3.674 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 2.800113e-04 | 3.553 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 2.800113e-04 | 3.553 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 2.800113e-04 | 3.553 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 3.123191e-04 | 3.505 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 3.406160e-04 | 3.468 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 3.616889e-04 | 3.442 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 3.721563e-04 | 3.429 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 4.039790e-04 | 3.394 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 4.675500e-04 | 3.330 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 4.918887e-04 | 3.308 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 4.996793e-04 | 3.301 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 5.144139e-04 | 3.289 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 5.257926e-04 | 3.279 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 5.658575e-04 | 3.247 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 6.657012e-04 | 3.177 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 7.146435e-04 | 3.146 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 7.118143e-04 | 3.148 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 7.183206e-04 | 3.144 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 7.396742e-04 | 3.131 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 8.107064e-04 | 3.091 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 8.107064e-04 | 3.091 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 8.478704e-04 | 3.072 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 8.478704e-04 | 3.072 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.022089e-03 | 2.991 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 9.979721e-04 | 3.001 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.023387e-03 | 2.990 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.189407e-03 | 2.925 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.189407e-03 | 2.925 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.189407e-03 | 2.925 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.189407e-03 | 2.925 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.096258e-03 | 2.960 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 1.164827e-03 | 2.934 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 1.279106e-03 | 2.893 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 1.279106e-03 | 2.893 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 1.364746e-03 | 2.865 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.364746e-03 | 2.865 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 1.536544e-03 | 2.813 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 1.688246e-03 | 2.773 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.694097e-03 | 2.771 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 1.828100e-03 | 2.738 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 1.824048e-03 | 2.739 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 1.828100e-03 | 2.738 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 1.826569e-03 | 2.738 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 2.310652e-03 | 2.636 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.324075e-03 | 2.634 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 2.335844e-03 | 2.632 | 0 | 0 |
| Protein folding | R-HSA-391251 | 2.578235e-03 | 2.589 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 2.611073e-03 | 2.583 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 2.832840e-03 | 2.548 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 2.904227e-03 | 2.537 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 3.358006e-03 | 2.474 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 3.725039e-03 | 2.429 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 3.502242e-03 | 2.456 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 3.571105e-03 | 2.447 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 3.999266e-03 | 2.398 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 4.637167e-03 | 2.334 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 4.654613e-03 | 2.332 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 4.804390e-03 | 2.318 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 4.804390e-03 | 2.318 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 5.164051e-03 | 2.287 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 5.164051e-03 | 2.287 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.487779e-03 | 2.261 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 5.487779e-03 | 2.261 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 5.996277e-03 | 2.222 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 6.727791e-03 | 2.172 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 7.038904e-03 | 2.152 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 7.345592e-03 | 2.134 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 7.807465e-03 | 2.107 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.012734e-03 | 2.096 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 8.196810e-03 | 2.086 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 8.986976e-03 | 2.046 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 8.614363e-03 | 2.065 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.211692e-03 | 2.036 | 1 | 0 |
| Developmental Biology | R-HSA-1266738 | 8.790485e-03 | 2.056 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 9.456430e-03 | 2.024 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 9.456430e-03 | 2.024 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 9.456430e-03 | 2.024 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 9.507806e-03 | 2.022 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.619494e-03 | 2.017 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 9.619494e-03 | 2.017 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 9.649654e-03 | 2.015 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.903576e-03 | 2.004 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 9.939299e-03 | 2.003 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 1.103518e-02 | 1.957 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 1.158860e-02 | 1.936 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.092676e-02 | 1.962 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.090987e-02 | 1.962 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.144544e-02 | 1.941 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.144544e-02 | 1.941 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 1.158409e-02 | 1.936 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.204692e-02 | 1.919 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 1.225768e-02 | 1.912 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.295258e-02 | 1.888 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 1.359202e-02 | 1.867 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 1.400705e-02 | 1.854 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.458572e-02 | 1.836 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.497701e-02 | 1.825 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 1.559520e-02 | 1.807 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 1.650810e-02 | 1.782 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.672345e-02 | 1.777 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 1.672345e-02 | 1.777 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.689434e-02 | 1.772 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 1.693190e-02 | 1.771 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 1.795040e-02 | 1.746 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 1.795040e-02 | 1.746 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 1.795040e-02 | 1.746 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 1.907337e-02 | 1.720 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 1.907337e-02 | 1.720 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.742956e-02 | 1.759 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 1.707660e-02 | 1.768 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.943100e-02 | 1.712 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.943100e-02 | 1.712 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 2.017476e-02 | 1.695 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.035677e-02 | 1.691 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.035677e-02 | 1.691 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 2.051466e-02 | 1.688 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.082266e-02 | 1.681 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 2.094737e-02 | 1.679 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 2.094737e-02 | 1.679 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 2.095353e-02 | 1.679 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 2.198881e-02 | 1.658 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 2.270409e-02 | 1.644 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 2.308871e-02 | 1.637 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 2.361110e-02 | 1.627 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 2.386933e-02 | 1.622 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 2.386933e-02 | 1.622 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 2.713545e-02 | 1.566 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.465683e-02 | 1.608 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 2.574603e-02 | 1.589 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 2.779201e-02 | 1.556 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.471911e-02 | 1.607 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 2.773667e-02 | 1.557 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 2.827651e-02 | 1.549 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 2.885365e-02 | 1.540 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 2.925625e-02 | 1.534 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 2.925625e-02 | 1.534 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 2.925625e-02 | 1.534 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 2.925625e-02 | 1.534 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 2.925625e-02 | 1.534 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 3.037940e-02 | 1.517 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 3.037940e-02 | 1.517 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 3.074555e-02 | 1.512 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 3.074555e-02 | 1.512 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 3.074555e-02 | 1.512 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 3.074555e-02 | 1.512 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 3.342041e-02 | 1.476 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 3.780991e-02 | 1.422 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 3.780991e-02 | 1.422 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 3.780991e-02 | 1.422 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 3.780991e-02 | 1.422 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.800526e-02 | 1.420 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 3.485441e-02 | 1.458 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.725084e-02 | 1.429 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 3.522979e-02 | 1.453 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 3.441804e-02 | 1.463 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 3.741489e-02 | 1.427 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 3.801523e-02 | 1.420 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 3.766861e-02 | 1.424 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 3.741489e-02 | 1.427 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.796658e-02 | 1.421 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 3.782487e-02 | 1.422 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 3.786617e-02 | 1.422 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 3.800526e-02 | 1.420 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 3.971922e-02 | 1.401 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 3.973004e-02 | 1.401 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 3.973004e-02 | 1.401 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 4.022096e-02 | 1.396 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 4.049787e-02 | 1.393 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 4.117926e-02 | 1.385 | 0 | 0 |
| Drug resistance of KIT mutants | R-HSA-9669937 | 4.941278e-02 | 1.306 | 0 | 0 |
| KIT mutants bind TKIs | R-HSA-9669921 | 4.941278e-02 | 1.306 | 0 | 0 |
| Dasatinib-resistant KIT mutants | R-HSA-9669914 | 4.941278e-02 | 1.306 | 0 | 0 |
| Masitinib-resistant KIT mutants | R-HSA-9669924 | 4.941278e-02 | 1.306 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 4.941278e-02 | 1.306 | 0 | 0 |
| Sorafenib-resistant KIT mutants | R-HSA-9669936 | 4.941278e-02 | 1.306 | 0 | 0 |
| Imatinib-resistant KIT mutants | R-HSA-9669917 | 4.941278e-02 | 1.306 | 0 | 0 |
| Regorafenib-resistant KIT mutants | R-HSA-9669929 | 4.941278e-02 | 1.306 | 0 | 0 |
| Sunitinib-resistant KIT mutants | R-HSA-9669934 | 4.941278e-02 | 1.306 | 0 | 0 |
| Nilotinib-resistant KIT mutants | R-HSA-9669926 | 4.941278e-02 | 1.306 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 4.941278e-02 | 1.306 | 0 | 0 |
| IRS activation | R-HSA-74713 | 4.980452e-02 | 1.303 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 4.178139e-02 | 1.379 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 4.889881e-02 | 1.311 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 4.889881e-02 | 1.311 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 4.889881e-02 | 1.311 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 4.889881e-02 | 1.311 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 4.889881e-02 | 1.311 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 4.889881e-02 | 1.311 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 4.889881e-02 | 1.311 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 4.889881e-02 | 1.311 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 4.755214e-02 | 1.323 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 4.889881e-02 | 1.311 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 4.980452e-02 | 1.303 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 4.178139e-02 | 1.379 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 4.889881e-02 | 1.311 | 0 | 0 |
| Inositol transporters | R-HSA-429593 | 4.980452e-02 | 1.303 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 4.404479e-02 | 1.356 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 4.889881e-02 | 1.311 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 4.598568e-02 | 1.337 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 4.924926e-02 | 1.308 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 5.003060e-02 | 1.301 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 4.603887e-02 | 1.337 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 4.264044e-02 | 1.370 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 4.980452e-02 | 1.303 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 4.694394e-02 | 1.328 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 5.019621e-02 | 1.299 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 5.032198e-02 | 1.298 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 5.034782e-02 | 1.298 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 5.136516e-02 | 1.289 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 5.178390e-02 | 1.286 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 5.393752e-02 | 1.268 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 5.489010e-02 | 1.261 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 5.571728e-02 | 1.254 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 5.571728e-02 | 1.254 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 5.571728e-02 | 1.254 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 5.571728e-02 | 1.254 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 5.571728e-02 | 1.254 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 5.656669e-02 | 1.247 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 5.707539e-02 | 1.244 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 5.713686e-02 | 1.243 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.296309e-02 | 1.201 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 6.476703e-02 | 1.189 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 7.347962e-02 | 1.134 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 7.347962e-02 | 1.134 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 6.170992e-02 | 1.210 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 6.802834e-02 | 1.167 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 6.802834e-02 | 1.167 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 5.938590e-02 | 1.226 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 6.385351e-02 | 1.195 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 6.296309e-02 | 1.201 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 6.802834e-02 | 1.167 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 6.330884e-02 | 1.199 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 6.476703e-02 | 1.189 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 6.079103e-02 | 1.216 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 6.079103e-02 | 1.216 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 6.079103e-02 | 1.216 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 6.079103e-02 | 1.216 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 6.998294e-02 | 1.155 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 7.347962e-02 | 1.134 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 7.108047e-02 | 1.148 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 6.079103e-02 | 1.216 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 6.811158e-02 | 1.167 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 6.811158e-02 | 1.167 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 7.273874e-02 | 1.138 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 6.915711e-02 | 1.160 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 7.184520e-02 | 1.144 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 6.296309e-02 | 1.201 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 7.215518e-02 | 1.142 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 7.392891e-02 | 1.131 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 6.998294e-02 | 1.155 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 7.373640e-02 | 1.132 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 7.347962e-02 | 1.134 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 6.998294e-02 | 1.155 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 6.998294e-02 | 1.155 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 6.814114e-02 | 1.167 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 6.294388e-02 | 1.201 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 7.371441e-02 | 1.132 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 7.536525e-02 | 1.123 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 7.547307e-02 | 1.122 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 7.714161e-02 | 1.113 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 8.118959e-02 | 1.090 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 8.162056e-02 | 1.088 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.162056e-02 | 1.088 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 8.251886e-02 | 1.083 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 8.268242e-02 | 1.083 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 8.343916e-02 | 1.079 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 8.378359e-02 | 1.077 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 8.673776e-02 | 1.062 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 8.683802e-02 | 1.061 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 8.712980e-02 | 1.060 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 8.712980e-02 | 1.060 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 8.888099e-02 | 1.051 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 8.888099e-02 | 1.051 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 8.888099e-02 | 1.051 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 8.888099e-02 | 1.051 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 9.220741e-02 | 1.035 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 9.220741e-02 | 1.035 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 9.220741e-02 | 1.035 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 9.220741e-02 | 1.035 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 9.220741e-02 | 1.035 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 9.220741e-02 | 1.035 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 9.638678e-02 | 1.016 | 0 | 0 |
| Hereditary fructose intolerance | R-HSA-5657560 | 9.638678e-02 | 1.016 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 9.638678e-02 | 1.016 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 9.638678e-02 | 1.016 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 9.638678e-02 | 1.016 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 9.638678e-02 | 1.016 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 1.080385e-01 | 0.966 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 1.042908e-01 | 0.982 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.124220e-01 | 0.949 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.062585e-01 | 0.974 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.062585e-01 | 0.974 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 1.130572e-01 | 0.947 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 1.130572e-01 | 0.947 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 9.299260e-02 | 1.032 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.104979e-01 | 0.957 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 1.080385e-01 | 0.966 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.844512e-02 | 1.007 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 1.033805e-01 | 0.986 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 9.616890e-02 | 1.017 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 1.113094e-01 | 0.953 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 9.329053e-02 | 1.030 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 1.200593e-01 | 0.921 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 1.213285e-01 | 0.916 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 9.526398e-02 | 1.021 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 1.239103e-01 | 0.907 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 1.080385e-01 | 0.966 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.099739e-01 | 0.959 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.119490e-01 | 0.951 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 1.062585e-01 | 0.974 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.710733e-02 | 1.013 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 9.638678e-02 | 1.016 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 1.129917e-01 | 0.947 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 1.129917e-01 | 0.947 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 1.062585e-01 | 0.974 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 1.062585e-01 | 0.974 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 1.158468e-01 | 0.936 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.200593e-01 | 0.921 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.033805e-01 | 0.986 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.121161e-01 | 0.950 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 1.130572e-01 | 0.947 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.157960e-01 | 0.936 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 1.080385e-01 | 0.966 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 1.129917e-01 | 0.947 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 1.129917e-01 | 0.947 | 0 | 0 |
| PKA activation | R-HSA-163615 | 1.129917e-01 | 0.947 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 1.129917e-01 | 0.947 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 1.020972e-01 | 0.991 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 1.129917e-01 | 0.947 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 1.041170e-01 | 0.982 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.130572e-01 | 0.947 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.052834e-01 | 0.978 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.130572e-01 | 0.947 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 1.099739e-01 | 0.959 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 1.140567e-01 | 0.943 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 1.245225e-01 | 0.905 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.245225e-01 | 0.905 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 1.245225e-01 | 0.905 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 1.245225e-01 | 0.905 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.245225e-01 | 0.905 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 1.245225e-01 | 0.905 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.245225e-01 | 0.905 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.245225e-01 | 0.905 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 1.245225e-01 | 0.905 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.269410e-01 | 0.896 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 1.269410e-01 | 0.896 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.282047e-01 | 0.892 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 1.294874e-01 | 0.888 | 0 | 0 |
| Signaling by extracellular domain mutants of KIT | R-HSA-9680187 | 1.410422e-01 | 0.851 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 1.410422e-01 | 0.851 | 0 | 0 |
| Signaling by juxtamembrane domain KIT mutants | R-HSA-9669935 | 1.410422e-01 | 0.851 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 1.410422e-01 | 0.851 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 1.410422e-01 | 0.851 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 1.410422e-01 | 0.851 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 1.410422e-01 | 0.851 | 0 | 0 |
| MPS IIID - Sanfilippo syndrome D | R-HSA-2206305 | 1.410422e-01 | 0.851 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 1.410422e-01 | 0.851 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 1.410422e-01 | 0.851 | 0 | 0 |
| Defective SLC12A3 causes Gitelman syndrome (GS) | R-HSA-5619087 | 1.410422e-01 | 0.851 | 0 | 0 |
| Signaling by kinase domain mutants of KIT | R-HSA-9669933 | 1.410422e-01 | 0.851 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 1.410422e-01 | 0.851 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 1.410422e-01 | 0.851 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5619081 | 1.410422e-01 | 0.851 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 1.410422e-01 | 0.851 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 1.410422e-01 | 0.851 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 1.410422e-01 | 0.851 | 0 | 0 |
| Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) | R-HSA-5660724 | 1.410422e-01 | 0.851 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 1.834934e-01 | 0.736 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 1.834934e-01 | 0.736 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 1.834934e-01 | 0.736 | 0 | 0 |
| Defective SLC12A1 causes Bartter syndrome 1 (BS1) | R-HSA-5619104 | 1.834934e-01 | 0.736 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 2.238491e-01 | 0.650 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 2.238491e-01 | 0.650 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 2.238491e-01 | 0.650 | 0 | 0 |
| Signalling to STAT3 | R-HSA-198745 | 2.238491e-01 | 0.650 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 2.622125e-01 | 0.581 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 2.622125e-01 | 0.581 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 2.622125e-01 | 0.581 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 2.622125e-01 | 0.581 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 2.622125e-01 | 0.581 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 2.622125e-01 | 0.581 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 2.622125e-01 | 0.581 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 2.622125e-01 | 0.581 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 2.622125e-01 | 0.581 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 1.415567e-01 | 0.849 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.590464e-01 | 0.798 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 1.590464e-01 | 0.798 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.590464e-01 | 0.798 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.590464e-01 | 0.798 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.590464e-01 | 0.798 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 2.986818e-01 | 0.525 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 2.986818e-01 | 0.525 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 2.986818e-01 | 0.525 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 2.986818e-01 | 0.525 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 1.769053e-01 | 0.752 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 1.769053e-01 | 0.752 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 1.950543e-01 | 0.710 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 1.950543e-01 | 0.710 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 3.333506e-01 | 0.477 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 2.134212e-01 | 0.671 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.587425e-01 | 0.799 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 1.587425e-01 | 0.799 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 3.663076e-01 | 0.436 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 3.663076e-01 | 0.436 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 3.663076e-01 | 0.436 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 3.663076e-01 | 0.436 | 0 | 0 |
| Defective CHST14 causes EDS, musculocontractural type | R-HSA-3595174 | 3.663076e-01 | 0.436 | 0 | 0 |
| Defective CHST3 causes SEDCJD | R-HSA-3595172 | 3.663076e-01 | 0.436 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 1.709564e-01 | 0.767 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 1.709564e-01 | 0.767 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 2.505518e-01 | 0.601 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 2.505518e-01 | 0.601 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.475508e-01 | 0.831 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 1.569282e-01 | 0.804 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.665201e-01 | 0.779 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 2.878401e-01 | 0.541 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.422321e-01 | 0.847 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.422321e-01 | 0.847 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.422321e-01 | 0.847 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 1.862985e-01 | 0.730 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 2.353776e-01 | 0.628 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 2.353776e-01 | 0.628 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.353776e-01 | 0.628 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 2.353776e-01 | 0.628 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.353776e-01 | 0.628 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 3.064232e-01 | 0.514 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 3.064232e-01 | 0.514 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 3.064232e-01 | 0.514 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.579266e-01 | 0.802 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 2.487583e-01 | 0.604 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 2.487583e-01 | 0.604 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 2.067869e-01 | 0.684 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 3.249110e-01 | 0.488 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 1.742909e-01 | 0.759 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 2.622497e-01 | 0.581 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 2.622497e-01 | 0.581 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 2.172660e-01 | 0.663 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 2.172660e-01 | 0.663 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 1.912695e-01 | 0.718 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 1.912695e-01 | 0.718 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 2.758298e-01 | 0.559 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.432675e-01 | 0.464 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.999712e-01 | 0.699 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 2.894774e-01 | 0.538 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 2.894774e-01 | 0.538 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 2.088045e-01 | 0.680 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 3.614604e-01 | 0.442 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 3.614604e-01 | 0.442 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 3.614604e-01 | 0.442 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 3.614604e-01 | 0.442 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 2.268361e-01 | 0.644 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.762684e-01 | 0.754 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 3.168950e-01 | 0.499 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.168950e-01 | 0.499 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 3.794613e-01 | 0.421 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 3.794613e-01 | 0.421 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 3.794613e-01 | 0.421 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 2.149903e-01 | 0.668 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 3.306271e-01 | 0.481 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 2.310580e-01 | 0.636 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 1.783290e-01 | 0.749 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 1.783290e-01 | 0.749 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.369405e-01 | 0.863 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 3.717069e-01 | 0.430 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 3.717069e-01 | 0.430 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 3.816995e-01 | 0.418 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 1.834279e-01 | 0.737 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 1.783290e-01 | 0.749 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 3.614604e-01 | 0.442 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 1.385357e-01 | 0.858 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 1.769053e-01 | 0.752 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 1.344785e-01 | 0.871 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.985401e-01 | 0.525 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 2.121252e-01 | 0.673 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.384000e-01 | 0.859 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.569282e-01 | 0.804 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.964603e-01 | 0.707 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.587425e-01 | 0.799 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.031723e-01 | 0.518 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 2.505518e-01 | 0.601 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 2.134212e-01 | 0.671 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 2.453036e-01 | 0.610 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 3.168950e-01 | 0.499 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 3.031723e-01 | 0.518 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 1.841083e-01 | 0.735 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 1.384000e-01 | 0.859 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.543216e-01 | 0.595 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 1.415567e-01 | 0.849 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 2.056062e-01 | 0.687 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.938552e-01 | 0.532 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 2.546817e-01 | 0.594 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 2.727244e-01 | 0.564 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 3.853085e-01 | 0.414 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.422321e-01 | 0.847 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.660284e-01 | 0.780 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.826457e-01 | 0.549 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 2.622125e-01 | 0.581 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 1.950543e-01 | 0.710 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 1.950543e-01 | 0.710 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 3.333506e-01 | 0.477 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 2.505518e-01 | 0.601 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 2.878401e-01 | 0.541 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 1.632354e-01 | 0.787 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 2.641457e-01 | 0.578 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 3.432675e-01 | 0.464 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 2.558275e-01 | 0.592 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 3.732077e-01 | 0.428 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 3.027103e-01 | 0.519 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 2.497991e-01 | 0.602 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 3.794613e-01 | 0.421 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 2.558275e-01 | 0.592 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 2.715119e-01 | 0.566 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 2.622125e-01 | 0.581 | 0 | 0 |
| PTK6 Activates STAT3 | R-HSA-8849474 | 2.986818e-01 | 0.525 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 2.986818e-01 | 0.525 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.986818e-01 | 0.525 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.950543e-01 | 0.710 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 3.333506e-01 | 0.477 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 3.663076e-01 | 0.436 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 3.168950e-01 | 0.499 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 3.646362e-01 | 0.438 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 1.964603e-01 | 0.707 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 3.094118e-01 | 0.509 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 3.124911e-01 | 0.505 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.618413e-01 | 0.441 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.738184e-01 | 0.760 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 1.916597e-01 | 0.717 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 2.622125e-01 | 0.581 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 3.333506e-01 | 0.477 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.505518e-01 | 0.601 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 3.853085e-01 | 0.414 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.957277e-01 | 0.529 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 2.229762e-01 | 0.652 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 2.319403e-01 | 0.635 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.763143e-01 | 0.754 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 2.172660e-01 | 0.663 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 2.172660e-01 | 0.663 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 3.443507e-01 | 0.463 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 1.516606e-01 | 0.819 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 2.353776e-01 | 0.628 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 3.443507e-01 | 0.463 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.833014e-01 | 0.548 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.360192e-01 | 0.627 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 3.247937e-01 | 0.488 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 3.443507e-01 | 0.463 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 3.892960e-01 | 0.410 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 1.410422e-01 | 0.851 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 1.834934e-01 | 0.736 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 1.834934e-01 | 0.736 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 1.834934e-01 | 0.736 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 2.622125e-01 | 0.581 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 1.590464e-01 | 0.798 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.590464e-01 | 0.798 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 2.986818e-01 | 0.525 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 1.769053e-01 | 0.752 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 1.769053e-01 | 0.752 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.769053e-01 | 0.752 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.769053e-01 | 0.752 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 3.333506e-01 | 0.477 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 3.333506e-01 | 0.477 | 0 | 0 |
| Synthesis of PS | R-HSA-1483101 | 3.333506e-01 | 0.477 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 3.333506e-01 | 0.477 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 3.333506e-01 | 0.477 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 3.333506e-01 | 0.477 | 0 | 0 |
| Intracellular metabolism of fatty acids regulates insulin secretion | R-HSA-434313 | 3.663076e-01 | 0.436 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 2.692015e-01 | 0.570 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 1.665201e-01 | 0.779 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 2.353776e-01 | 0.628 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 3.064232e-01 | 0.514 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 3.249110e-01 | 0.488 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 2.172660e-01 | 0.663 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 3.306271e-01 | 0.481 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 2.546817e-01 | 0.594 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.546817e-01 | 0.594 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.546817e-01 | 0.594 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 3.443507e-01 | 0.463 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 2.736882e-01 | 0.563 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 3.580493e-01 | 0.446 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.853085e-01 | 0.414 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 2.134212e-01 | 0.671 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 1.385499e-01 | 0.858 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 1.999712e-01 | 0.699 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 2.962758e-01 | 0.528 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.961309e-01 | 0.707 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 1.966116e-01 | 0.706 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 3.641095e-01 | 0.439 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 2.845083e-01 | 0.546 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.422321e-01 | 0.847 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 2.986818e-01 | 0.525 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.090400e-01 | 0.680 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.692015e-01 | 0.570 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 3.743398e-01 | 0.427 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 1.709564e-01 | 0.767 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 2.894774e-01 | 0.538 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 3.623903e-01 | 0.441 | 1 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 3.067842e-01 | 0.513 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.865347e-01 | 0.729 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 2.134212e-01 | 0.671 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 3.168950e-01 | 0.499 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 3.306271e-01 | 0.481 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 3.850746e-01 | 0.414 | 1 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 3.623903e-01 | 0.441 | 1 | 1 |
| Circadian clock | R-HSA-9909396 | 2.227654e-01 | 0.652 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 3.850746e-01 | 0.414 | 1 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.709564e-01 | 0.767 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 2.487583e-01 | 0.604 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.827070e-01 | 0.738 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 3.732077e-01 | 0.428 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.320679e-01 | 0.634 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.896322e-01 | 0.722 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.064232e-01 | 0.514 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 2.962758e-01 | 0.528 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.692015e-01 | 0.570 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 3.421671e-01 | 0.466 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 3.321692e-01 | 0.479 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 1.410422e-01 | 0.851 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 2.622125e-01 | 0.581 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 2.622125e-01 | 0.581 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 2.986818e-01 | 0.525 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 3.333506e-01 | 0.477 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 3.663076e-01 | 0.436 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 2.505518e-01 | 0.601 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 2.505518e-01 | 0.601 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 2.067869e-01 | 0.684 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 3.614604e-01 | 0.442 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 2.641457e-01 | 0.578 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.822907e-01 | 0.739 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 2.920851e-01 | 0.534 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 1.587425e-01 | 0.799 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.817185e-01 | 0.418 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 3.333506e-01 | 0.477 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 2.134212e-01 | 0.671 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.506550e-01 | 0.822 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 3.817185e-01 | 0.418 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 3.663076e-01 | 0.436 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 3.168950e-01 | 0.499 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 3.794613e-01 | 0.421 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 3.443507e-01 | 0.463 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 3.580493e-01 | 0.446 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 3.446751e-01 | 0.463 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 3.168950e-01 | 0.499 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 2.878401e-01 | 0.541 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 3.513456e-01 | 0.454 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 1.506550e-01 | 0.822 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 2.758298e-01 | 0.559 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 2.622125e-01 | 0.581 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 2.622125e-01 | 0.581 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 1.415567e-01 | 0.849 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 2.986818e-01 | 0.525 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 2.986818e-01 | 0.525 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 2.986818e-01 | 0.525 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.986818e-01 | 0.525 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.769053e-01 | 0.752 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 1.950543e-01 | 0.710 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 3.333506e-01 | 0.477 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 3.333506e-01 | 0.477 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.587425e-01 | 0.799 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.587425e-01 | 0.799 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 3.663076e-01 | 0.436 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.090400e-01 | 0.680 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 2.067869e-01 | 0.684 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 2.622497e-01 | 0.581 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 2.667441e-01 | 0.574 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 3.336180e-01 | 0.477 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 2.360192e-01 | 0.627 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 3.794613e-01 | 0.421 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 2.196515e-01 | 0.658 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 2.134212e-01 | 0.671 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 1.660284e-01 | 0.780 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 3.853085e-01 | 0.414 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 3.484069e-01 | 0.458 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 2.736882e-01 | 0.563 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 2.898792e-01 | 0.538 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 1.569282e-01 | 0.804 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.346525e-01 | 0.871 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 3.027972e-01 | 0.519 | 1 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 2.090400e-01 | 0.680 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 3.249309e-01 | 0.488 | 1 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 3.415443e-01 | 0.467 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 3.333506e-01 | 0.477 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 3.333506e-01 | 0.477 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 3.663076e-01 | 0.436 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 3.663076e-01 | 0.436 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 3.663076e-01 | 0.436 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.505518e-01 | 0.601 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 2.505518e-01 | 0.601 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 2.878401e-01 | 0.541 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 2.067869e-01 | 0.684 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 3.031723e-01 | 0.518 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 2.244270e-01 | 0.649 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 3.173953e-01 | 0.498 | 1 | 1 |
| Interleukin-17 signaling | R-HSA-448424 | 3.618719e-01 | 0.441 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 3.173953e-01 | 0.498 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 3.173953e-01 | 0.498 | 1 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 2.833014e-01 | 0.548 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.623903e-01 | 0.441 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 2.411463e-01 | 0.618 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 3.614604e-01 | 0.442 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 3.168950e-01 | 0.499 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 3.794613e-01 | 0.421 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 1.468124e-01 | 0.833 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.715119e-01 | 0.566 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.551313e-01 | 0.809 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 3.173953e-01 | 0.498 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 1.587425e-01 | 0.799 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 2.278850e-01 | 0.642 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 2.736882e-01 | 0.563 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 2.473023e-01 | 0.607 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 1.912695e-01 | 0.718 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 3.616790e-01 | 0.442 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 2.134212e-01 | 0.671 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 3.333506e-01 | 0.477 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 1.468124e-01 | 0.833 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 2.505518e-01 | 0.601 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 2.505518e-01 | 0.601 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 3.432675e-01 | 0.464 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 3.717069e-01 | 0.430 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 3.853085e-01 | 0.414 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 2.878401e-01 | 0.541 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 2.894774e-01 | 0.538 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 1.763143e-01 | 0.754 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 3.164046e-01 | 0.500 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 3.443507e-01 | 0.463 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 1.453413e-01 | 0.838 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.432675e-01 | 0.464 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 3.443507e-01 | 0.463 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 3.926530e-01 | 0.406 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 3.941442e-01 | 0.404 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 3.950976e-01 | 0.403 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 3.956038e-01 | 0.403 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 3.958826e-01 | 0.402 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 3.958826e-01 | 0.402 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.958826e-01 | 0.402 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 3.958966e-01 | 0.402 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 3.972446e-01 | 0.401 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 3.972446e-01 | 0.401 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 3.972446e-01 | 0.401 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 3.972446e-01 | 0.401 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 3.972446e-01 | 0.401 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 3.976372e-01 | 0.401 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 3.976372e-01 | 0.401 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 3.976372e-01 | 0.401 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 3.976372e-01 | 0.401 | 0 | 0 |
| Defective CHSY1 causes TPBS | R-HSA-3595177 | 3.976372e-01 | 0.401 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 3.976372e-01 | 0.401 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 3.976372e-01 | 0.401 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 3.976372e-01 | 0.401 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 3.976372e-01 | 0.401 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.976372e-01 | 0.401 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 3.976372e-01 | 0.401 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 3.976372e-01 | 0.401 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 3.976372e-01 | 0.401 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 3.976372e-01 | 0.401 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 3.976372e-01 | 0.401 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 3.976372e-01 | 0.401 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 3.988401e-01 | 0.399 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 3.988401e-01 | 0.399 | 0 | 0 |
| Depurination | R-HSA-73927 | 3.988401e-01 | 0.399 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 3.988401e-01 | 0.399 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 4.048088e-01 | 0.393 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 4.067299e-01 | 0.391 | 1 | 1 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 4.071735e-01 | 0.390 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 4.071735e-01 | 0.390 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 4.071735e-01 | 0.390 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 4.071735e-01 | 0.390 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.122882e-01 | 0.385 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 4.137111e-01 | 0.383 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 4.147879e-01 | 0.382 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.147879e-01 | 0.382 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 4.147879e-01 | 0.382 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 4.148926e-01 | 0.382 | 1 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 4.213733e-01 | 0.375 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 4.225991e-01 | 0.374 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 4.256406e-01 | 0.371 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.256406e-01 | 0.371 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.256406e-01 | 0.371 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 4.256406e-01 | 0.371 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 4.256406e-01 | 0.371 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 4.256406e-01 | 0.371 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 4.256406e-01 | 0.371 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 4.274196e-01 | 0.369 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 4.274196e-01 | 0.369 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 4.274196e-01 | 0.369 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 4.274196e-01 | 0.369 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 4.274196e-01 | 0.369 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.274196e-01 | 0.369 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 4.274196e-01 | 0.369 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 4.274196e-01 | 0.369 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 4.320715e-01 | 0.364 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 4.320715e-01 | 0.364 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 4.320715e-01 | 0.364 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 4.320715e-01 | 0.364 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 4.388855e-01 | 0.358 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 4.388855e-01 | 0.358 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 4.388855e-01 | 0.358 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 4.388855e-01 | 0.358 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 4.393171e-01 | 0.357 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 4.393171e-01 | 0.357 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 4.407611e-01 | 0.356 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 4.409222e-01 | 0.356 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 4.453383e-01 | 0.351 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 4.490783e-01 | 0.348 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 4.490783e-01 | 0.348 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 4.491359e-01 | 0.348 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 4.518366e-01 | 0.345 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 4.518366e-01 | 0.345 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.518366e-01 | 0.345 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 4.520122e-01 | 0.345 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 4.520122e-01 | 0.345 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 4.520122e-01 | 0.345 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 4.557313e-01 | 0.341 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 4.557313e-01 | 0.341 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 4.557313e-01 | 0.341 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 4.557313e-01 | 0.341 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 4.557313e-01 | 0.341 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 4.557313e-01 | 0.341 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 4.557313e-01 | 0.341 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 4.557313e-01 | 0.341 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 4.557313e-01 | 0.341 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 4.557313e-01 | 0.341 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 4.557313e-01 | 0.341 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 4.557313e-01 | 0.341 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 4.557313e-01 | 0.341 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 4.557313e-01 | 0.341 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 4.557313e-01 | 0.341 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 4.557313e-01 | 0.341 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 4.557313e-01 | 0.341 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 4.557313e-01 | 0.341 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 4.557313e-01 | 0.341 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 4.557313e-01 | 0.341 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 4.579258e-01 | 0.339 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 4.628401e-01 | 0.335 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 4.628401e-01 | 0.335 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 4.650105e-01 | 0.333 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 4.650105e-01 | 0.333 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 4.650105e-01 | 0.333 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 4.650381e-01 | 0.333 | 1 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 4.657933e-01 | 0.332 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 4.657933e-01 | 0.332 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 4.657933e-01 | 0.332 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 4.657933e-01 | 0.332 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 4.657933e-01 | 0.332 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 4.657933e-01 | 0.332 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 4.657933e-01 | 0.332 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 4.657933e-01 | 0.332 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 4.657933e-01 | 0.332 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 4.657933e-01 | 0.332 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 4.666814e-01 | 0.331 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 4.737651e-01 | 0.324 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 4.737651e-01 | 0.324 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 4.778713e-01 | 0.321 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 4.778713e-01 | 0.321 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 4.796625e-01 | 0.319 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 4.822038e-01 | 0.317 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 4.822038e-01 | 0.317 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 4.822038e-01 | 0.317 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 4.822038e-01 | 0.317 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 4.822038e-01 | 0.317 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 4.822038e-01 | 0.317 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 4.822038e-01 | 0.317 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 4.826446e-01 | 0.316 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 4.826446e-01 | 0.316 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 4.826446e-01 | 0.316 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 4.826446e-01 | 0.316 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 4.826446e-01 | 0.316 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 4.826446e-01 | 0.316 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 4.826446e-01 | 0.316 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 4.826446e-01 | 0.316 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 4.826446e-01 | 0.316 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 4.826446e-01 | 0.316 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 4.826446e-01 | 0.316 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 4.846523e-01 | 0.315 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 4.905860e-01 | 0.309 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 4.927063e-01 | 0.307 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 4.930339e-01 | 0.307 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 4.972039e-01 | 0.303 | 1 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 4.982992e-01 | 0.303 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 4.982992e-01 | 0.303 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 4.982992e-01 | 0.303 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 4.982992e-01 | 0.303 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 4.982992e-01 | 0.303 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 5.031466e-01 | 0.298 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 5.031466e-01 | 0.298 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 5.031466e-01 | 0.298 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 5.031466e-01 | 0.298 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 5.031466e-01 | 0.298 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 5.034305e-01 | 0.298 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 5.060085e-01 | 0.296 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 5.082287e-01 | 0.294 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 5.082287e-01 | 0.294 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 5.082287e-01 | 0.294 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 5.082287e-01 | 0.294 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 5.082287e-01 | 0.294 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 5.082287e-01 | 0.294 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 5.082287e-01 | 0.294 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 5.082287e-01 | 0.294 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 5.082287e-01 | 0.294 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 5.082287e-01 | 0.294 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 5.082287e-01 | 0.294 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 5.098208e-01 | 0.293 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 5.098208e-01 | 0.293 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 5.125921e-01 | 0.290 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 5.140704e-01 | 0.289 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 5.140704e-01 | 0.289 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 5.140704e-01 | 0.289 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 5.155461e-01 | 0.288 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 5.155461e-01 | 0.288 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 5.155461e-01 | 0.288 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 5.155461e-01 | 0.288 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 5.155461e-01 | 0.288 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 5.155461e-01 | 0.288 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 5.174564e-01 | 0.286 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 5.271296e-01 | 0.278 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 5.277778e-01 | 0.278 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 5.295102e-01 | 0.276 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.295102e-01 | 0.276 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 5.295102e-01 | 0.276 | 0 | 0 |
| DS-GAG biosynthesis | R-HSA-2022923 | 5.325491e-01 | 0.274 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 5.325491e-01 | 0.274 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 5.325491e-01 | 0.274 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 5.325491e-01 | 0.274 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 5.325491e-01 | 0.274 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 5.325491e-01 | 0.274 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 5.325491e-01 | 0.274 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 5.350767e-01 | 0.272 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 5.373419e-01 | 0.270 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 5.398359e-01 | 0.268 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 5.398359e-01 | 0.268 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 5.409990e-01 | 0.267 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 5.433731e-01 | 0.265 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 5.433731e-01 | 0.265 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 5.446128e-01 | 0.264 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 5.446128e-01 | 0.264 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 5.446128e-01 | 0.264 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 5.446128e-01 | 0.264 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 5.446128e-01 | 0.264 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 5.446128e-01 | 0.264 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 5.446128e-01 | 0.264 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 5.470409e-01 | 0.262 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 5.486328e-01 | 0.261 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 5.498805e-01 | 0.260 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 5.517152e-01 | 0.258 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 5.556682e-01 | 0.255 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 5.556682e-01 | 0.255 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 5.556682e-01 | 0.255 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 5.556682e-01 | 0.255 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 5.556682e-01 | 0.255 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 5.556682e-01 | 0.255 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 5.556682e-01 | 0.255 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 5.556682e-01 | 0.255 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 5.556682e-01 | 0.255 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 5.576634e-01 | 0.254 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 5.576634e-01 | 0.254 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 5.576634e-01 | 0.254 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 5.593738e-01 | 0.252 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 5.634109e-01 | 0.249 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 5.634918e-01 | 0.249 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 5.649500e-01 | 0.248 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 5.676422e-01 | 0.246 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 5.678590e-01 | 0.246 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 5.678590e-01 | 0.246 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 5.687623e-01 | 0.245 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 5.727475e-01 | 0.242 | 0 | 0 |
| Disease | R-HSA-1643685 | 5.734192e-01 | 0.242 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 5.749188e-01 | 0.240 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 5.749188e-01 | 0.240 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 5.749188e-01 | 0.240 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 5.758788e-01 | 0.240 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 5.776451e-01 | 0.238 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 5.776451e-01 | 0.238 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 5.776451e-01 | 0.238 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 5.776451e-01 | 0.238 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 5.776451e-01 | 0.238 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 5.776451e-01 | 0.238 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 5.776451e-01 | 0.238 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 5.776451e-01 | 0.238 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 5.776451e-01 | 0.238 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 5.776451e-01 | 0.238 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 5.838239e-01 | 0.234 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 5.838239e-01 | 0.234 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 5.862352e-01 | 0.232 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 5.862352e-01 | 0.232 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 5.872188e-01 | 0.231 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 5.878593e-01 | 0.231 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 5.878593e-01 | 0.231 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 5.878593e-01 | 0.231 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 5.878593e-01 | 0.231 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 5.878593e-01 | 0.231 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 5.878593e-01 | 0.231 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 5.888502e-01 | 0.230 | 1 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 5.903749e-01 | 0.229 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 5.940318e-01 | 0.226 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 5.968110e-01 | 0.224 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 5.968110e-01 | 0.224 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 5.973572e-01 | 0.224 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 5.985364e-01 | 0.223 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 5.985364e-01 | 0.223 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 5.985364e-01 | 0.223 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 5.985364e-01 | 0.223 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 5.985364e-01 | 0.223 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 5.985364e-01 | 0.223 | 0 | 0 |
| N-glycan trimming and elongation in the cis-Golgi | R-HSA-964739 | 5.985364e-01 | 0.223 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 5.985364e-01 | 0.223 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 5.985364e-01 | 0.223 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 5.985364e-01 | 0.223 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 5.985364e-01 | 0.223 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 5.985364e-01 | 0.223 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 5.985364e-01 | 0.223 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 5.994821e-01 | 0.222 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 6.015810e-01 | 0.221 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 6.062688e-01 | 0.217 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 6.062688e-01 | 0.217 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 6.071916e-01 | 0.217 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 6.082819e-01 | 0.216 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 6.148190e-01 | 0.211 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 6.149549e-01 | 0.211 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 6.149549e-01 | 0.211 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 6.149549e-01 | 0.211 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 6.149549e-01 | 0.211 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 6.149549e-01 | 0.211 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 6.149549e-01 | 0.211 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.149549e-01 | 0.211 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 6.183955e-01 | 0.209 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 6.183955e-01 | 0.209 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 6.183955e-01 | 0.209 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 6.183955e-01 | 0.209 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 6.183955e-01 | 0.209 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 6.183955e-01 | 0.209 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 6.183955e-01 | 0.209 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 6.183955e-01 | 0.209 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 6.183955e-01 | 0.209 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 6.183955e-01 | 0.209 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 6.183955e-01 | 0.209 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 6.183955e-01 | 0.209 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 6.183955e-01 | 0.209 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 6.183955e-01 | 0.209 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 6.183955e-01 | 0.209 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 6.183955e-01 | 0.209 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 6.190072e-01 | 0.208 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 6.249479e-01 | 0.204 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 6.279818e-01 | 0.202 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 6.279818e-01 | 0.202 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 6.279818e-01 | 0.202 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 6.279818e-01 | 0.202 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 6.279818e-01 | 0.202 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 6.295313e-01 | 0.201 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 6.295313e-01 | 0.201 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 6.295313e-01 | 0.201 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 6.298218e-01 | 0.201 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 6.372733e-01 | 0.196 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 6.372733e-01 | 0.196 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 6.372733e-01 | 0.196 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 6.372733e-01 | 0.196 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 6.372733e-01 | 0.196 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 6.372733e-01 | 0.196 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 6.372733e-01 | 0.196 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 6.372733e-01 | 0.196 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 6.372733e-01 | 0.196 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 6.372733e-01 | 0.196 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 6.372733e-01 | 0.196 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 6.372733e-01 | 0.196 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 6.372733e-01 | 0.196 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 6.372733e-01 | 0.196 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 6.372733e-01 | 0.196 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 6.372733e-01 | 0.196 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 6.372733e-01 | 0.196 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 6.372733e-01 | 0.196 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 6.372733e-01 | 0.196 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 6.398529e-01 | 0.194 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 6.406634e-01 | 0.193 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 6.406634e-01 | 0.193 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 6.406634e-01 | 0.193 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 6.406634e-01 | 0.193 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 6.406634e-01 | 0.193 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 6.406634e-01 | 0.193 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 6.444794e-01 | 0.191 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 6.444794e-01 | 0.191 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 6.492401e-01 | 0.188 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 6.499708e-01 | 0.187 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 6.512374e-01 | 0.186 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 6.530019e-01 | 0.185 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 6.530019e-01 | 0.185 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 6.530019e-01 | 0.185 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 6.552184e-01 | 0.184 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 6.552184e-01 | 0.184 | 0 | 0 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | R-HSA-4420332 | 6.552184e-01 | 0.184 | 0 | 0 |
| Defective B4GALT7 causes EDS, progeroid type | R-HSA-3560783 | 6.552184e-01 | 0.184 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 6.552184e-01 | 0.184 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 6.552184e-01 | 0.184 | 0 | 0 |
| Scavenging by Class B Receptors | R-HSA-3000471 | 6.552184e-01 | 0.184 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 6.552184e-01 | 0.184 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 6.552184e-01 | 0.184 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 6.552184e-01 | 0.184 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 6.552184e-01 | 0.184 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 6.552184e-01 | 0.184 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 6.552184e-01 | 0.184 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 6.566453e-01 | 0.183 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 6.598846e-01 | 0.181 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 6.598846e-01 | 0.181 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 6.600866e-01 | 0.180 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 6.616390e-01 | 0.179 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 6.700281e-01 | 0.174 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 6.722767e-01 | 0.172 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 6.722767e-01 | 0.172 | 0 | 0 |
| Defective B3GAT3 causes JDSSDHD | R-HSA-3560801 | 6.722767e-01 | 0.172 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 6.722767e-01 | 0.172 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 6.722767e-01 | 0.172 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 6.722767e-01 | 0.172 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 6.722767e-01 | 0.172 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 6.766618e-01 | 0.170 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 6.766618e-01 | 0.170 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 6.766618e-01 | 0.170 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 6.766618e-01 | 0.170 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 6.768768e-01 | 0.169 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 6.790985e-01 | 0.168 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 6.790985e-01 | 0.168 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 6.795551e-01 | 0.168 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 6.879906e-01 | 0.162 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 6.879906e-01 | 0.162 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 6.883990e-01 | 0.162 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 6.883990e-01 | 0.162 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 6.883990e-01 | 0.162 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 6.884920e-01 | 0.162 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 6.884920e-01 | 0.162 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 6.884920e-01 | 0.162 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 6.884920e-01 | 0.162 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 6.884920e-01 | 0.162 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 6.921157e-01 | 0.160 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 6.921157e-01 | 0.160 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 6.989910e-01 | 0.156 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 6.989910e-01 | 0.156 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 6.992495e-01 | 0.155 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 6.992495e-01 | 0.155 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 7.008657e-01 | 0.154 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 7.009640e-01 | 0.154 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 7.039059e-01 | 0.152 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 7.039059e-01 | 0.152 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 7.039059e-01 | 0.152 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 7.039059e-01 | 0.152 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 7.039059e-01 | 0.152 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 7.039059e-01 | 0.152 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 7.039059e-01 | 0.152 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 7.039059e-01 | 0.152 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 7.039059e-01 | 0.152 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 7.039059e-01 | 0.152 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 7.039059e-01 | 0.152 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 7.039059e-01 | 0.152 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 7.063493e-01 | 0.151 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 7.063901e-01 | 0.151 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 7.063901e-01 | 0.151 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 7.063901e-01 | 0.151 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 7.068684e-01 | 0.151 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 7.096677e-01 | 0.149 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 7.096677e-01 | 0.149 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 7.096677e-01 | 0.149 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 7.096677e-01 | 0.149 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 7.162882e-01 | 0.145 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 7.185581e-01 | 0.144 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 7.185581e-01 | 0.144 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 7.185581e-01 | 0.144 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 7.185581e-01 | 0.144 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 7.185581e-01 | 0.144 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 7.185581e-01 | 0.144 | 0 | 0 |
| Keratan sulfate degradation | R-HSA-2022857 | 7.185581e-01 | 0.144 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 7.185581e-01 | 0.144 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 7.185581e-01 | 0.144 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 7.185581e-01 | 0.144 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 7.185581e-01 | 0.144 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 7.200258e-01 | 0.143 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 7.237305e-01 | 0.140 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 7.248059e-01 | 0.140 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 7.300707e-01 | 0.137 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 7.300707e-01 | 0.137 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 7.318681e-01 | 0.136 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 7.318681e-01 | 0.136 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 7.324860e-01 | 0.135 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 7.324860e-01 | 0.135 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 7.324860e-01 | 0.135 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 7.324860e-01 | 0.135 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 7.324860e-01 | 0.135 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 7.324860e-01 | 0.135 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 7.324860e-01 | 0.135 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 7.324860e-01 | 0.135 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 7.324860e-01 | 0.135 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 7.381781e-01 | 0.132 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 7.398081e-01 | 0.131 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 7.398081e-01 | 0.131 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 7.398081e-01 | 0.131 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 7.398081e-01 | 0.131 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 7.398081e-01 | 0.131 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 7.399643e-01 | 0.131 | 0 | 0 |
| CS-GAG biosynthesis | R-HSA-2022870 | 7.457254e-01 | 0.127 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 7.457254e-01 | 0.127 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 7.457254e-01 | 0.127 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 7.457254e-01 | 0.127 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 7.457254e-01 | 0.127 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 7.478652e-01 | 0.126 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 7.492436e-01 | 0.125 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 7.492436e-01 | 0.125 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 7.492436e-01 | 0.125 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 7.492436e-01 | 0.125 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 7.492436e-01 | 0.125 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.541920e-01 | 0.123 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 7.555730e-01 | 0.122 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 7.555730e-01 | 0.122 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 7.583104e-01 | 0.120 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.583104e-01 | 0.120 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 7.583104e-01 | 0.120 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 7.583104e-01 | 0.120 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 7.587670e-01 | 0.120 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 7.589132e-01 | 0.120 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 7.630898e-01 | 0.117 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 7.630898e-01 | 0.117 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 7.630898e-01 | 0.117 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 7.672337e-01 | 0.115 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 7.702732e-01 | 0.113 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 7.702732e-01 | 0.113 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 7.702732e-01 | 0.113 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 7.702732e-01 | 0.113 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 7.702732e-01 | 0.113 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.702732e-01 | 0.113 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 7.702732e-01 | 0.113 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 7.704179e-01 | 0.113 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 7.704179e-01 | 0.113 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 7.717821e-01 | 0.113 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 7.717821e-01 | 0.113 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 7.758005e-01 | 0.110 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 7.775598e-01 | 0.109 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 7.815513e-01 | 0.107 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 7.816446e-01 | 0.107 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 7.816446e-01 | 0.107 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 7.816446e-01 | 0.107 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.816446e-01 | 0.107 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 7.816446e-01 | 0.107 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 7.840904e-01 | 0.106 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 7.840904e-01 | 0.106 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 7.840904e-01 | 0.106 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 7.842394e-01 | 0.106 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 7.864020e-01 | 0.104 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 7.912954e-01 | 0.102 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 7.921097e-01 | 0.101 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 7.924538e-01 | 0.101 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 7.924538e-01 | 0.101 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 7.924538e-01 | 0.101 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 7.924538e-01 | 0.101 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 7.924538e-01 | 0.101 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 7.925218e-01 | 0.101 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 8.027285e-01 | 0.095 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 8.027285e-01 | 0.095 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 8.027285e-01 | 0.095 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 8.027285e-01 | 0.095 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 8.027285e-01 | 0.095 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 8.027285e-01 | 0.095 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 8.043181e-01 | 0.095 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 8.073625e-01 | 0.093 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.073625e-01 | 0.093 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 8.073625e-01 | 0.093 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.073625e-01 | 0.093 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 8.105692e-01 | 0.091 | 0 | 0 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | R-HSA-83936 | 8.124952e-01 | 0.090 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 8.124952e-01 | 0.090 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 8.124952e-01 | 0.090 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 8.124952e-01 | 0.090 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 8.146089e-01 | 0.089 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 8.146089e-01 | 0.089 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 8.166508e-01 | 0.088 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 8.216106e-01 | 0.085 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 8.217789e-01 | 0.085 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 8.217789e-01 | 0.085 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 8.217789e-01 | 0.085 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 8.217789e-01 | 0.085 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 8.217789e-01 | 0.085 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 8.225657e-01 | 0.085 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 8.236127e-01 | 0.084 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.268061e-01 | 0.083 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 8.283742e-01 | 0.082 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 8.306034e-01 | 0.081 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.306034e-01 | 0.081 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 8.306034e-01 | 0.081 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 8.306034e-01 | 0.081 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 8.306034e-01 | 0.081 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 8.306034e-01 | 0.081 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 8.349059e-01 | 0.078 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 8.389916e-01 | 0.076 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 8.389916e-01 | 0.076 | 0 | 0 |
| Mucopolysaccharidoses | R-HSA-2206281 | 8.389916e-01 | 0.076 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 8.410132e-01 | 0.075 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 8.412122e-01 | 0.075 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 8.446212e-01 | 0.073 | 0 | 0 |
| S Phase | R-HSA-69242 | 8.450260e-01 | 0.073 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 8.469648e-01 | 0.072 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 8.469648e-01 | 0.072 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 8.469648e-01 | 0.072 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 8.469648e-01 | 0.072 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 8.469648e-01 | 0.072 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 8.472993e-01 | 0.072 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 8.479444e-01 | 0.072 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 8.524553e-01 | 0.069 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.531736e-01 | 0.069 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 8.545437e-01 | 0.068 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 8.545437e-01 | 0.068 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 8.568523e-01 | 0.067 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.588410e-01 | 0.066 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 8.595654e-01 | 0.066 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 8.617477e-01 | 0.065 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 8.617477e-01 | 0.065 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 8.617477e-01 | 0.065 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 8.617477e-01 | 0.065 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 8.637864e-01 | 0.064 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 8.643077e-01 | 0.063 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 8.653121e-01 | 0.063 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 8.685134e-01 | 0.061 | 0 | 0 |
| CS/DS degradation | R-HSA-2024101 | 8.685953e-01 | 0.061 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.685953e-01 | 0.061 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 8.685953e-01 | 0.061 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 8.685953e-01 | 0.061 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 8.685953e-01 | 0.061 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 8.685953e-01 | 0.061 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 8.685953e-01 | 0.061 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 8.685953e-01 | 0.061 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 8.695797e-01 | 0.061 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 8.739385e-01 | 0.059 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 8.746629e-01 | 0.058 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 8.746629e-01 | 0.058 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 8.746629e-01 | 0.058 | 0 | 0 |
| Glycosaminoglycan-protein linkage region biosynthesis | R-HSA-1971475 | 8.751041e-01 | 0.058 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 8.751041e-01 | 0.058 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 8.751041e-01 | 0.058 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 8.751041e-01 | 0.058 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 8.751041e-01 | 0.058 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 8.774063e-01 | 0.057 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 8.775222e-01 | 0.057 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 8.806272e-01 | 0.055 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 8.812909e-01 | 0.055 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 8.812909e-01 | 0.055 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 8.812909e-01 | 0.055 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 8.816807e-01 | 0.055 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 8.871716e-01 | 0.052 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 8.871716e-01 | 0.052 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 8.871716e-01 | 0.052 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 8.888361e-01 | 0.051 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.896222e-01 | 0.051 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 8.896222e-01 | 0.051 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 8.927613e-01 | 0.049 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 8.927613e-01 | 0.049 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 8.927613e-01 | 0.049 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 8.927613e-01 | 0.049 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.934114e-01 | 0.049 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 8.980744e-01 | 0.047 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 8.980744e-01 | 0.047 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 8.980744e-01 | 0.047 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 9.006413e-01 | 0.045 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 9.006413e-01 | 0.045 | 1 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 9.031246e-01 | 0.044 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.031246e-01 | 0.044 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.031246e-01 | 0.044 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 9.033687e-01 | 0.044 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 9.040879e-01 | 0.044 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 9.079249e-01 | 0.042 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 9.079249e-01 | 0.042 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.079249e-01 | 0.042 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 9.079249e-01 | 0.042 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 9.079249e-01 | 0.042 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.079249e-01 | 0.042 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 9.079249e-01 | 0.042 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.091968e-01 | 0.041 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 9.124875e-01 | 0.040 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.124875e-01 | 0.040 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.124875e-01 | 0.040 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.124875e-01 | 0.040 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.137886e-01 | 0.039 | 0 | 0 |
| Translation | R-HSA-72766 | 9.148753e-01 | 0.039 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.163187e-01 | 0.038 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.163887e-01 | 0.038 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.168244e-01 | 0.038 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 9.168244e-01 | 0.038 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 9.168244e-01 | 0.038 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.168244e-01 | 0.038 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.187077e-01 | 0.037 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 9.196798e-01 | 0.036 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.196798e-01 | 0.036 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 9.209466e-01 | 0.036 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.209466e-01 | 0.036 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.225888e-01 | 0.035 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 9.248647e-01 | 0.034 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 9.272536e-01 | 0.033 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.279908e-01 | 0.032 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.285888e-01 | 0.032 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.285888e-01 | 0.032 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.285888e-01 | 0.032 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.318937e-01 | 0.031 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.321286e-01 | 0.031 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.321286e-01 | 0.031 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 9.321286e-01 | 0.031 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 9.321286e-01 | 0.031 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.321286e-01 | 0.031 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 9.346606e-01 | 0.029 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 9.354931e-01 | 0.029 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.354931e-01 | 0.029 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.354931e-01 | 0.029 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.354931e-01 | 0.029 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 9.386910e-01 | 0.027 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.386910e-01 | 0.027 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.386910e-01 | 0.027 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.386910e-01 | 0.027 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.396467e-01 | 0.027 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.396467e-01 | 0.027 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 9.400155e-01 | 0.027 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.417306e-01 | 0.026 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 9.431755e-01 | 0.025 | 0 | 0 |
| Keratan sulfate/keratin metabolism | R-HSA-1638074 | 9.446196e-01 | 0.025 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.446982e-01 | 0.025 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.473656e-01 | 0.023 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.480175e-01 | 0.023 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.501582e-01 | 0.022 | 1 | 1 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 9.524563e-01 | 0.021 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.548141e-01 | 0.020 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.554519e-01 | 0.020 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.570468e-01 | 0.019 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.570468e-01 | 0.019 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.570468e-01 | 0.019 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.570552e-01 | 0.019 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.588297e-01 | 0.018 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.591852e-01 | 0.018 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.605415e-01 | 0.017 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.612097e-01 | 0.017 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.616949e-01 | 0.017 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 9.624525e-01 | 0.017 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.631339e-01 | 0.016 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.649627e-01 | 0.015 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.659491e-01 | 0.015 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.659491e-01 | 0.015 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.667010e-01 | 0.015 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.667301e-01 | 0.015 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.671086e-01 | 0.015 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.681249e-01 | 0.014 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.683531e-01 | 0.014 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.683531e-01 | 0.014 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.685479e-01 | 0.014 | 1 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.691884e-01 | 0.014 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 9.697040e-01 | 0.013 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.699233e-01 | 0.013 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.699233e-01 | 0.013 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.714157e-01 | 0.013 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.719793e-01 | 0.012 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.727615e-01 | 0.012 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.737147e-01 | 0.012 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.741823e-01 | 0.011 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.741823e-01 | 0.011 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.742949e-01 | 0.011 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.746427e-01 | 0.011 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.754823e-01 | 0.011 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.761289e-01 | 0.010 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.789388e-01 | 0.009 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.793423e-01 | 0.009 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.801310e-01 | 0.009 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.809780e-01 | 0.008 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.810530e-01 | 0.008 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.819224e-01 | 0.008 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.819224e-01 | 0.008 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.819224e-01 | 0.008 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.823271e-01 | 0.008 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.828199e-01 | 0.008 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.836730e-01 | 0.007 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.842056e-01 | 0.007 | 0 | 0 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 9.844837e-01 | 0.007 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.852543e-01 | 0.006 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 9.852543e-01 | 0.006 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.860399e-01 | 0.006 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.866826e-01 | 0.006 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.873440e-01 | 0.006 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.879726e-01 | 0.005 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.879812e-01 | 0.005 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.886085e-01 | 0.005 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.891379e-01 | 0.005 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.891379e-01 | 0.005 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.892886e-01 | 0.005 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.906778e-01 | 0.004 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.919996e-01 | 0.003 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.919996e-01 | 0.003 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.924931e-01 | 0.003 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.927751e-01 | 0.003 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.948033e-01 | 0.002 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.958022e-01 | 0.002 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.962771e-01 | 0.002 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.963779e-01 | 0.002 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 9.975294e-01 | 0.001 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.979822e-01 | 0.001 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.980752e-01 | 0.001 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.981561e-01 | 0.001 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.991534e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.992271e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.993443e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.995540e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.996072e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.996355e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.997252e-01 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 9.997520e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 9.997609e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.997761e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.997978e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.998359e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.999196e-01 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 9.999247e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999566e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999605e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999957e-01 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 9.999961e-01 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 9.999985e-01 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 1.000000e+00 | 0.000 | 1 | 1 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
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| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.110223e-16 | 15.955 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 1.110223e-16 | 15.955 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 1.110223e-16 | 15.955 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 1.110223e-16 | 15.955 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 1.110223e-16 | 15.955 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 1.110223e-16 | 15.955 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.110223e-16 | 15.955 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.110223e-16 | 15.955 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.110223e-16 | 15.955 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.110223e-16 | 15.955 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.110223e-16 | 15.955 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 2.220446e-16 | 15.654 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 3.330669e-16 | 15.477 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 6.661338e-16 | 15.176 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 6.661338e-16 | 15.176 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 1.110223e-15 | 14.955 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.998401e-15 | 14.699 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 3.885781e-15 | 14.411 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 5.440093e-15 | 14.264 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 5.773160e-15 | 14.239 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 1.343370e-14 | 13.872 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 2.275957e-14 | 13.643 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 2.275957e-14 | 13.643 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 2.586820e-14 | 13.587 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 3.108624e-14 | 13.507 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 4.507505e-14 | 13.346 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 6.794565e-14 | 13.168 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 7.971401e-14 | 13.098 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 2.287059e-13 | 12.641 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 2.420286e-13 | 12.616 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 3.167466e-13 | 12.499 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 3.086420e-13 | 12.511 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 3.671508e-13 | 12.435 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 3.671508e-13 | 12.435 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 5.726530e-13 | 12.242 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 7.049916e-13 | 12.152 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 8.242296e-13 | 12.084 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 1.543432e-12 | 11.812 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 1.145206e-11 | 10.941 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.255229e-11 | 10.901 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 1.731459e-11 | 10.762 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 2.059586e-11 | 10.686 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 2.121869e-11 | 10.673 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 2.315292e-11 | 10.635 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.189959e-11 | 10.496 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 3.850187e-11 | 10.415 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 4.896150e-11 | 10.310 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 5.269152e-11 | 10.278 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 5.503109e-11 | 10.259 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 7.523426e-11 | 10.124 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 9.375667e-11 | 10.028 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 1.118478e-10 | 9.951 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 1.153309e-10 | 9.938 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 1.195096e-10 | 9.923 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.295616e-10 | 9.888 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.430053e-10 | 9.845 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 1.831715e-10 | 9.737 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.908051e-10 | 9.719 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 2.136515e-10 | 9.670 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.136515e-10 | 9.670 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 2.213620e-10 | 9.655 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 2.399738e-10 | 9.620 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 3.239693e-10 | 9.489 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 3.821693e-10 | 9.418 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 4.190288e-10 | 9.378 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 5.162538e-10 | 9.287 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 5.339879e-10 | 9.272 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 6.711062e-10 | 9.173 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 7.924423e-10 | 9.101 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 8.994655e-10 | 9.046 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 8.994655e-10 | 9.046 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 8.994655e-10 | 9.046 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 8.994655e-10 | 9.046 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 1.199912e-09 | 8.921 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 1.221256e-09 | 8.913 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.269891e-09 | 8.896 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 2.132449e-09 | 8.671 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 2.142645e-09 | 8.669 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.158121e-09 | 8.666 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.526712e-09 | 8.597 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 3.397451e-09 | 8.469 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.397451e-09 | 8.469 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 3.402774e-09 | 8.468 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 3.595839e-09 | 8.444 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 3.661600e-09 | 8.436 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 4.346374e-09 | 8.362 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 4.390295e-09 | 8.358 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 4.524095e-09 | 8.344 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 4.617340e-09 | 8.336 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 5.080481e-09 | 8.294 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 5.388758e-09 | 8.269 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 6.498485e-09 | 8.187 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 6.615009e-09 | 8.179 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 8.240606e-09 | 8.084 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 8.367375e-09 | 8.077 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 8.865236e-09 | 8.052 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 1.033660e-08 | 7.986 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.043615e-08 | 7.981 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 1.193574e-08 | 7.923 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 1.193574e-08 | 7.923 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 1.263481e-08 | 7.898 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 1.858602e-08 | 7.731 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.996800e-08 | 7.700 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 2.174225e-08 | 7.663 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 2.715829e-08 | 7.566 | 0 | 0 |
| Translation | R-HSA-72766 | 2.752414e-08 | 7.560 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 2.773930e-08 | 7.557 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 3.275283e-08 | 7.485 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 4.000630e-08 | 7.398 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 4.129299e-08 | 7.384 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 4.559575e-08 | 7.341 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 6.467498e-08 | 7.189 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 6.674407e-08 | 7.176 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 6.886836e-08 | 7.162 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 6.923232e-08 | 7.160 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 7.549390e-08 | 7.122 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 9.477263e-08 | 7.023 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 9.826970e-08 | 7.008 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.113051e-07 | 6.953 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.130370e-07 | 6.947 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.130370e-07 | 6.947 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 1.130370e-07 | 6.947 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 1.155066e-07 | 6.937 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 1.314492e-07 | 6.881 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 1.420101e-07 | 6.848 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 1.420101e-07 | 6.848 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.552592e-07 | 6.809 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 1.604109e-07 | 6.795 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.623287e-07 | 6.790 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 1.726131e-07 | 6.763 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.732572e-07 | 6.761 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.804152e-07 | 6.744 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 2.003980e-07 | 6.698 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 2.171805e-07 | 6.663 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 2.355708e-07 | 6.628 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 2.389589e-07 | 6.622 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 2.455420e-07 | 6.610 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 2.602634e-07 | 6.585 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 2.941399e-07 | 6.531 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 2.946595e-07 | 6.531 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 2.993859e-07 | 6.524 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 3.273359e-07 | 6.485 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 3.211512e-07 | 6.493 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 3.333535e-07 | 6.477 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 3.369582e-07 | 6.472 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 3.588746e-07 | 6.445 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 3.665471e-07 | 6.436 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 3.762478e-07 | 6.425 | 0 | 0 |
| Kinesins | R-HSA-983189 | 3.922354e-07 | 6.406 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 4.337373e-07 | 6.363 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 4.453269e-07 | 6.351 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 4.772121e-07 | 6.321 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 5.386759e-07 | 6.269 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 6.429474e-07 | 6.192 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 6.851028e-07 | 6.164 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 7.994841e-07 | 6.097 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 8.515741e-07 | 6.070 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 8.584340e-07 | 6.066 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 8.713332e-07 | 6.060 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 8.754662e-07 | 6.058 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 8.976777e-07 | 6.047 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 8.976777e-07 | 6.047 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 9.224053e-07 | 6.035 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 9.493648e-07 | 6.023 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.702188e-07 | 6.013 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.226600e-06 | 5.911 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.228768e-06 | 5.911 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 1.228768e-06 | 5.911 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 1.305650e-06 | 5.884 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 1.463231e-06 | 5.835 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.560658e-06 | 5.807 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 1.702306e-06 | 5.769 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 1.854993e-06 | 5.732 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 1.863903e-06 | 5.730 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 1.972137e-06 | 5.705 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 2.042383e-06 | 5.690 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 2.090058e-06 | 5.680 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 2.414241e-06 | 5.617 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 2.669334e-06 | 5.574 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 2.870208e-06 | 5.542 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 2.951898e-06 | 5.530 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 3.200720e-06 | 5.495 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 3.397559e-06 | 5.469 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 3.635372e-06 | 5.439 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.390615e-06 | 5.357 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 4.493845e-06 | 5.347 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 4.728214e-06 | 5.325 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 4.929359e-06 | 5.307 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 5.096806e-06 | 5.293 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 5.096806e-06 | 5.293 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 5.342788e-06 | 5.272 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 6.021179e-06 | 5.220 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 6.130544e-06 | 5.213 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.485589e-06 | 5.188 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 6.697438e-06 | 5.174 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 8.017944e-06 | 5.096 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 1.084340e-05 | 4.965 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 1.118241e-05 | 4.951 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 1.306433e-05 | 4.884 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.312832e-05 | 4.882 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.386102e-05 | 4.858 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 1.407904e-05 | 4.851 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 1.427305e-05 | 4.845 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 1.510032e-05 | 4.821 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 1.544607e-05 | 4.811 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.554747e-05 | 4.808 | 0 | 0 |
| Protein folding | R-HSA-391251 | 1.654706e-05 | 4.781 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.693060e-05 | 4.771 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.751739e-05 | 4.757 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 1.912159e-05 | 4.718 | 0 | 0 |
| Depurination | R-HSA-73927 | 1.930967e-05 | 4.714 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.973412e-05 | 4.705 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.243930e-05 | 4.649 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 2.412051e-05 | 4.618 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.652656e-05 | 4.576 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 2.691053e-05 | 4.570 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 2.510237e-05 | 4.600 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 2.510237e-05 | 4.600 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 3.006802e-05 | 4.522 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 3.010164e-05 | 4.521 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 3.389391e-05 | 4.470 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 3.804291e-05 | 4.420 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 4.145897e-05 | 4.382 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 4.769897e-05 | 4.321 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 5.112943e-05 | 4.291 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 5.112943e-05 | 4.291 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 5.140370e-05 | 4.289 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 5.313563e-05 | 4.275 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 5.359123e-05 | 4.271 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 5.694456e-05 | 4.245 | 1 | 1 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 5.694456e-05 | 4.245 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 5.694456e-05 | 4.245 | 1 | 0 |
| Immune System | R-HSA-168256 | 5.718011e-05 | 4.243 | 1 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 5.915911e-05 | 4.228 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 6.804959e-05 | 4.167 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 6.194716e-05 | 4.208 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 6.501369e-05 | 4.187 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 7.417071e-05 | 4.130 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 7.690607e-05 | 4.114 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 8.254465e-05 | 4.083 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 8.814891e-05 | 4.055 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 9.117043e-05 | 4.040 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 9.117043e-05 | 4.040 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 9.225111e-05 | 4.035 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 9.287730e-05 | 4.032 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 9.343937e-05 | 4.029 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 9.407823e-05 | 4.027 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 9.407823e-05 | 4.027 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 9.492197e-05 | 4.023 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 9.909795e-05 | 4.004 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 1.032035e-04 | 3.986 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 1.062494e-04 | 3.974 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.091925e-04 | 3.962 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.091925e-04 | 3.962 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.151065e-04 | 3.939 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.158553e-04 | 3.936 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 1.207077e-04 | 3.918 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 1.259878e-04 | 3.900 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.288950e-04 | 3.890 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 1.370279e-04 | 3.863 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 1.441689e-04 | 3.841 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 1.454227e-04 | 3.837 | 1 | 1 |
| Semaphorin interactions | R-HSA-373755 | 1.519910e-04 | 3.818 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.543362e-04 | 3.812 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 1.543362e-04 | 3.812 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.596108e-04 | 3.797 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 1.684837e-04 | 3.773 | 1 | 0 |
| Glycolysis | R-HSA-70171 | 1.746999e-04 | 3.758 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.927187e-04 | 3.715 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.983847e-04 | 3.702 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.008379e-04 | 3.697 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 2.033237e-04 | 3.692 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.077074e-04 | 3.683 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 2.086518e-04 | 3.681 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 2.107728e-04 | 3.676 | 1 | 1 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 2.107728e-04 | 3.676 | 1 | 0 |
| Muscle contraction | R-HSA-397014 | 2.155350e-04 | 3.666 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 2.173096e-04 | 3.663 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 2.179603e-04 | 3.662 | 1 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 2.331401e-04 | 3.632 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 2.357754e-04 | 3.628 | 1 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 2.360151e-04 | 3.627 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 2.488219e-04 | 3.604 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 2.613907e-04 | 3.583 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.630799e-04 | 3.580 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 2.643250e-04 | 3.578 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 2.753946e-04 | 3.560 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.767504e-04 | 3.558 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 2.849276e-04 | 3.545 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 2.849276e-04 | 3.545 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 2.849276e-04 | 3.545 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 2.946196e-04 | 3.531 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 2.946196e-04 | 3.531 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 2.946196e-04 | 3.531 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 2.946196e-04 | 3.531 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 2.970132e-04 | 3.527 | 1 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.971124e-04 | 3.527 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 3.145761e-04 | 3.502 | 1 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 3.145761e-04 | 3.502 | 1 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 4.005433e-04 | 3.397 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 3.880086e-04 | 3.411 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 3.670989e-04 | 3.435 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 3.550460e-04 | 3.450 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 3.987435e-04 | 3.399 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 4.158987e-04 | 3.381 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 4.164518e-04 | 3.380 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 4.320093e-04 | 3.365 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 4.648642e-04 | 3.333 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 4.713066e-04 | 3.327 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 4.925092e-04 | 3.308 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 5.095624e-04 | 3.293 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 5.446278e-04 | 3.264 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 5.492716e-04 | 3.260 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 5.827083e-04 | 3.235 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 6.123015e-04 | 3.213 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 6.123015e-04 | 3.213 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 6.143107e-04 | 3.212 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 6.370598e-04 | 3.196 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 6.370598e-04 | 3.196 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 6.620770e-04 | 3.179 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 7.100852e-04 | 3.149 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 7.355056e-04 | 3.133 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 7.383032e-04 | 3.132 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 7.484691e-04 | 3.126 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 7.730976e-04 | 3.112 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 7.780774e-04 | 3.109 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 7.903238e-04 | 3.102 | 0 | 0 |
| S Phase | R-HSA-69242 | 8.284892e-04 | 3.082 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 8.433955e-04 | 3.074 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 8.555603e-04 | 3.068 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 8.572495e-04 | 3.067 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 8.654027e-04 | 3.063 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 8.654027e-04 | 3.063 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 8.654895e-04 | 3.063 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 9.027089e-04 | 3.044 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 9.232377e-04 | 3.035 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 9.385983e-04 | 3.028 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 9.385983e-04 | 3.028 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 9.738811e-04 | 3.011 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 1.005529e-03 | 2.998 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 1.059316e-03 | 2.975 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 1.066140e-03 | 2.972 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 1.157040e-03 | 2.937 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 1.321119e-03 | 2.879 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 1.355403e-03 | 2.868 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 1.217026e-03 | 2.915 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 1.084880e-03 | 2.965 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.217026e-03 | 2.915 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 1.179197e-03 | 2.928 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.157040e-03 | 2.937 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.340084e-03 | 2.873 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.353843e-03 | 2.868 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 1.319649e-03 | 2.880 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.314120e-03 | 2.881 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.340084e-03 | 2.873 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 1.319649e-03 | 2.880 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 1.319649e-03 | 2.880 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.211435e-03 | 2.917 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.250472e-03 | 2.903 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.267511e-03 | 2.897 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.355403e-03 | 2.868 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.343827e-03 | 2.872 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 1.147540e-03 | 2.940 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 1.147540e-03 | 2.940 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 1.375977e-03 | 2.861 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.394656e-03 | 2.856 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.425412e-03 | 2.846 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 1.473617e-03 | 2.832 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 1.484000e-03 | 2.829 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 1.489931e-03 | 2.827 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 1.489931e-03 | 2.827 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 1.613396e-03 | 2.792 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 1.671158e-03 | 2.777 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.702586e-03 | 2.769 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 1.714145e-03 | 2.766 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 1.714145e-03 | 2.766 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.714145e-03 | 2.766 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 1.714145e-03 | 2.766 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 1.726424e-03 | 2.763 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 1.726424e-03 | 2.763 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.794713e-03 | 2.746 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 1.858149e-03 | 2.731 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 1.858149e-03 | 2.731 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.858149e-03 | 2.731 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 1.882032e-03 | 2.725 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 1.882032e-03 | 2.725 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 1.882032e-03 | 2.725 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 1.921352e-03 | 2.716 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.960144e-03 | 2.708 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 2.058974e-03 | 2.686 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 2.115686e-03 | 2.675 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 2.115686e-03 | 2.675 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 2.127848e-03 | 2.672 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 2.127848e-03 | 2.672 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 2.127848e-03 | 2.672 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 2.144342e-03 | 2.669 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 2.190945e-03 | 2.659 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 2.263520e-03 | 2.645 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 2.271724e-03 | 2.644 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 2.282350e-03 | 2.642 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 2.282350e-03 | 2.642 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 2.282350e-03 | 2.642 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 2.282350e-03 | 2.642 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 2.335197e-03 | 2.632 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 2.418577e-03 | 2.616 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.500213e-03 | 2.602 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 2.572151e-03 | 2.590 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 2.597128e-03 | 2.586 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 2.636916e-03 | 2.579 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 2.636916e-03 | 2.579 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 2.636916e-03 | 2.579 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 2.646323e-03 | 2.577 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.688511e-03 | 2.570 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 2.723287e-03 | 2.565 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.758017e-03 | 2.559 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.758865e-03 | 2.559 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 2.758865e-03 | 2.559 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 2.766271e-03 | 2.558 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 2.795001e-03 | 2.554 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 2.841873e-03 | 2.546 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 2.878800e-03 | 2.541 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 3.005590e-03 | 2.522 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 3.005590e-03 | 2.522 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 3.703791e-03 | 2.431 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.703791e-03 | 2.431 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 4.012355e-03 | 2.397 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 4.012355e-03 | 2.397 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 3.619806e-03 | 2.441 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 3.974175e-03 | 2.401 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.016345e-03 | 2.521 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 3.204080e-03 | 2.494 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 3.050898e-03 | 2.516 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 3.406916e-03 | 2.468 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 3.889389e-03 | 2.410 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 3.703791e-03 | 2.431 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 3.204080e-03 | 2.494 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 3.204080e-03 | 2.494 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 3.288916e-03 | 2.483 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 3.478123e-03 | 2.459 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 3.974175e-03 | 2.401 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 3.514115e-03 | 2.454 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 3.703791e-03 | 2.431 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 3.951975e-03 | 2.403 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 4.029086e-03 | 2.395 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 4.176925e-03 | 2.379 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 4.176925e-03 | 2.379 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 4.176925e-03 | 2.379 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 4.263650e-03 | 2.370 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 4.263650e-03 | 2.370 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 4.474863e-03 | 2.349 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 4.527877e-03 | 2.344 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 4.527877e-03 | 2.344 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 4.527877e-03 | 2.344 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 4.617453e-03 | 2.336 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 4.619052e-03 | 2.335 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 4.689349e-03 | 2.329 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 4.749829e-03 | 2.323 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 4.749829e-03 | 2.323 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 4.749829e-03 | 2.323 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 4.750220e-03 | 2.323 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 4.825563e-03 | 2.316 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 4.825563e-03 | 2.316 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 4.825563e-03 | 2.316 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 4.825563e-03 | 2.316 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 4.845994e-03 | 2.315 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 4.845994e-03 | 2.315 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 4.920108e-03 | 2.308 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 4.969660e-03 | 2.304 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 5.015487e-03 | 2.300 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 5.194633e-03 | 2.284 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 5.416636e-03 | 2.266 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 5.489393e-03 | 2.260 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 5.510823e-03 | 2.259 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 5.579051e-03 | 2.253 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 5.595094e-03 | 2.252 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 5.595094e-03 | 2.252 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 5.607788e-03 | 2.251 | 1 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 5.617291e-03 | 2.250 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 5.617291e-03 | 2.250 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 5.643795e-03 | 2.248 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 5.643795e-03 | 2.248 | 0 | 0 |
| Disease | R-HSA-1643685 | 5.968681e-03 | 2.224 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 6.027807e-03 | 2.220 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 6.297109e-03 | 2.201 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 6.297109e-03 | 2.201 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 6.482630e-03 | 2.188 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 6.482630e-03 | 2.188 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 6.482757e-03 | 2.188 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 6.482757e-03 | 2.188 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 6.482757e-03 | 2.188 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 6.616955e-03 | 2.179 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 6.654936e-03 | 2.177 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 6.654936e-03 | 2.177 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 6.661512e-03 | 2.176 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 6.661512e-03 | 2.176 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 6.661512e-03 | 2.176 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 6.661512e-03 | 2.176 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 6.687233e-03 | 2.175 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 6.687233e-03 | 2.175 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 6.800400e-03 | 2.167 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 6.886938e-03 | 2.162 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 7.327549e-03 | 2.135 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 7.601782e-03 | 2.119 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 7.621628e-03 | 2.118 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 7.758037e-03 | 2.110 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 7.775887e-03 | 2.109 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 7.775887e-03 | 2.109 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 7.806416e-03 | 2.108 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 7.913813e-03 | 2.102 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 7.915549e-03 | 2.102 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 8.033597e-03 | 2.095 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 8.225124e-03 | 2.085 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 8.315356e-03 | 2.080 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 8.538248e-03 | 2.069 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 8.835180e-03 | 2.054 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 9.107120e-03 | 2.041 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 9.107920e-03 | 2.041 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 9.107920e-03 | 2.041 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 9.107920e-03 | 2.041 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 9.107920e-03 | 2.041 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 9.107920e-03 | 2.041 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 9.107920e-03 | 2.041 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 9.111308e-03 | 2.040 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 9.245499e-03 | 2.034 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 9.308582e-03 | 2.031 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 9.308582e-03 | 2.031 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 9.312205e-03 | 2.031 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 9.366144e-03 | 2.028 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 9.366144e-03 | 2.028 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 9.407028e-03 | 2.027 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.786716e-03 | 2.009 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 9.820266e-03 | 2.008 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 1.000262e-02 | 2.000 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 1.058309e-02 | 1.975 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 1.061484e-02 | 1.974 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 1.061484e-02 | 1.974 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 1.089803e-02 | 1.963 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.103447e-02 | 1.957 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.103447e-02 | 1.957 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.103447e-02 | 1.957 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 1.104619e-02 | 1.957 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 1.104619e-02 | 1.957 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 1.117009e-02 | 1.952 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 1.117009e-02 | 1.952 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 1.133786e-02 | 1.945 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 1.203195e-02 | 1.920 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 1.746325e-02 | 1.758 | 0 | 0 |
| Signaling by RAS GAP mutants | R-HSA-9753510 | 1.746325e-02 | 1.758 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.563536e-02 | 1.806 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 1.563536e-02 | 1.806 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 1.563536e-02 | 1.806 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.220971e-02 | 1.913 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 1.580790e-02 | 1.801 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.228399e-02 | 1.911 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.228399e-02 | 1.911 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 1.763206e-02 | 1.754 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 1.297346e-02 | 1.887 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 1.570534e-02 | 1.804 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.325916e-02 | 1.877 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.325916e-02 | 1.877 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 1.325380e-02 | 1.878 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 1.341842e-02 | 1.872 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 1.272823e-02 | 1.895 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 1.530125e-02 | 1.815 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.522338e-02 | 1.817 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 1.344727e-02 | 1.871 | 1 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 1.763206e-02 | 1.754 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 1.722610e-02 | 1.764 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 1.828407e-02 | 1.738 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 1.635311e-02 | 1.786 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 1.694681e-02 | 1.771 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 1.530125e-02 | 1.815 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.325380e-02 | 1.878 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 1.561629e-02 | 1.806 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 1.469610e-02 | 1.833 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 1.561629e-02 | 1.806 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 1.230462e-02 | 1.910 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 1.725136e-02 | 1.763 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 1.763206e-02 | 1.754 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.694087e-02 | 1.771 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 1.286490e-02 | 1.891 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 1.406001e-02 | 1.852 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.561629e-02 | 1.806 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 1.580790e-02 | 1.801 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.530125e-02 | 1.815 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 1.765502e-02 | 1.753 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 1.592781e-02 | 1.798 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 1.228399e-02 | 1.911 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 1.841841e-02 | 1.735 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 1.864205e-02 | 1.730 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 1.870703e-02 | 1.728 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 1.916109e-02 | 1.718 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.015415e-02 | 1.696 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 2.040757e-02 | 1.690 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.040757e-02 | 1.690 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 2.093533e-02 | 1.679 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 2.117723e-02 | 1.674 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 2.181240e-02 | 1.661 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 2.181240e-02 | 1.661 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 2.185255e-02 | 1.660 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.198270e-02 | 1.658 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 2.219647e-02 | 1.654 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 2.241686e-02 | 1.649 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.241686e-02 | 1.649 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 2.243307e-02 | 1.649 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 2.272694e-02 | 1.643 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 2.344795e-02 | 1.630 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.404793e-02 | 1.619 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 2.404793e-02 | 1.619 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 2.404793e-02 | 1.619 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 2.404793e-02 | 1.619 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.404793e-02 | 1.619 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 2.419291e-02 | 1.616 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 2.419291e-02 | 1.616 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 2.450225e-02 | 1.611 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 2.450225e-02 | 1.611 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 2.450225e-02 | 1.611 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 2.452950e-02 | 1.610 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 2.462291e-02 | 1.609 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.462291e-02 | 1.609 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 2.545225e-02 | 1.594 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 2.566009e-02 | 1.591 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 2.629178e-02 | 1.580 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.629178e-02 | 1.580 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 2.645804e-02 | 1.577 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.681152e-02 | 1.572 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 2.686445e-02 | 1.571 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 2.686445e-02 | 1.571 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 2.696938e-02 | 1.569 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 2.794230e-02 | 1.554 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 2.833628e-02 | 1.548 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.890377e-02 | 1.539 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 2.929961e-02 | 1.533 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 2.929961e-02 | 1.533 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 2.929961e-02 | 1.533 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 2.965514e-02 | 1.528 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 3.009158e-02 | 1.522 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 3.034769e-02 | 1.518 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 3.051581e-02 | 1.515 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 3.051581e-02 | 1.515 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 3.091746e-02 | 1.510 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 3.099469e-02 | 1.509 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 3.107996e-02 | 1.508 | 1 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 3.152526e-02 | 1.501 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 3.187929e-02 | 1.496 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 3.235215e-02 | 1.490 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 3.243912e-02 | 1.489 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 3.278048e-02 | 1.484 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 3.285573e-02 | 1.483 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.285573e-02 | 1.483 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 3.474863e-02 | 1.459 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.605324e-02 | 1.443 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 3.614286e-02 | 1.442 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 3.626239e-02 | 1.441 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 3.642253e-02 | 1.439 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 3.701003e-02 | 1.432 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 3.701003e-02 | 1.432 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 3.701003e-02 | 1.432 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.845071e-02 | 1.415 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 3.845071e-02 | 1.415 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 3.845071e-02 | 1.415 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 3.845071e-02 | 1.415 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 3.849900e-02 | 1.415 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 3.901266e-02 | 1.409 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 4.075010e-02 | 1.390 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 4.165773e-02 | 1.380 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 4.278911e-02 | 1.369 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 4.278911e-02 | 1.369 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 4.278911e-02 | 1.369 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 4.383582e-02 | 1.358 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 4.548831e-02 | 1.342 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 4.548831e-02 | 1.342 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.590867e-02 | 1.338 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 4.590867e-02 | 1.338 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 4.590867e-02 | 1.338 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.590867e-02 | 1.338 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 4.590867e-02 | 1.338 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 4.590867e-02 | 1.338 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 4.590867e-02 | 1.338 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 4.590867e-02 | 1.338 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 4.641268e-02 | 1.333 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 4.705128e-02 | 1.327 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 4.726536e-02 | 1.325 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 4.726536e-02 | 1.325 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 4.751690e-02 | 1.323 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 4.782945e-02 | 1.320 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 4.851832e-02 | 1.314 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 4.851832e-02 | 1.314 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 4.851832e-02 | 1.314 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 5.071845e-02 | 1.295 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 5.071845e-02 | 1.295 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 5.123846e-02 | 1.290 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 5.174184e-02 | 1.286 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 5.207460e-02 | 1.283 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 5.309961e-02 | 1.275 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 5.309961e-02 | 1.275 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 5.332050e-02 | 1.273 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 5.332050e-02 | 1.273 | 1 | 1 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 5.434459e-02 | 1.265 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 5.458667e-02 | 1.263 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 5.529592e-02 | 1.257 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 5.529592e-02 | 1.257 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 5.529592e-02 | 1.257 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 5.579180e-02 | 1.253 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 5.579180e-02 | 1.253 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 5.602965e-02 | 1.252 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 5.602965e-02 | 1.252 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 5.602965e-02 | 1.252 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 5.940214e-02 | 1.226 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 5.940214e-02 | 1.226 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 6.194441e-02 | 1.208 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 6.258568e-02 | 1.204 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 6.258568e-02 | 1.204 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 6.258568e-02 | 1.204 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 6.258568e-02 | 1.204 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 6.258568e-02 | 1.204 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 6.258568e-02 | 1.204 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 6.258568e-02 | 1.204 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 6.321240e-02 | 1.199 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 6.321240e-02 | 1.199 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 6.321240e-02 | 1.199 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 6.321240e-02 | 1.199 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 6.321240e-02 | 1.199 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 6.321240e-02 | 1.199 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 6.321240e-02 | 1.199 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 6.447421e-02 | 1.191 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 6.447421e-02 | 1.191 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 6.516826e-02 | 1.186 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 6.516826e-02 | 1.186 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 6.666422e-02 | 1.176 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 6.666422e-02 | 1.176 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 6.666422e-02 | 1.176 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 6.666422e-02 | 1.176 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 6.739041e-02 | 1.171 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 6.739041e-02 | 1.171 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 6.753355e-02 | 1.170 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 6.753355e-02 | 1.170 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 6.753355e-02 | 1.170 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 6.753355e-02 | 1.170 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 6.753355e-02 | 1.170 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 6.753355e-02 | 1.170 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 6.753355e-02 | 1.170 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 6.991423e-02 | 1.155 | 0 | 0 |
| IRS activation | R-HSA-74713 | 6.998330e-02 | 1.155 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 6.998330e-02 | 1.155 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 6.998330e-02 | 1.155 | 0 | 0 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 6.998330e-02 | 1.155 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 6.998330e-02 | 1.155 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 7.084616e-02 | 1.150 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 7.144121e-02 | 1.146 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 7.345156e-02 | 1.134 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 7.396731e-02 | 1.131 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 7.419583e-02 | 1.130 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 7.569662e-02 | 1.121 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 7.603903e-02 | 1.119 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 7.603903e-02 | 1.119 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 7.831989e-02 | 1.106 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 7.838984e-02 | 1.106 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 7.999193e-02 | 1.097 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 8.090608e-02 | 1.092 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 8.090608e-02 | 1.092 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 8.090608e-02 | 1.092 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 8.090608e-02 | 1.092 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 8.121289e-02 | 1.090 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 8.121289e-02 | 1.090 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 8.174896e-02 | 1.088 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 8.174896e-02 | 1.088 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 8.174896e-02 | 1.088 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 8.233812e-02 | 1.084 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 8.233812e-02 | 1.084 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 8.544344e-02 | 1.068 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 8.544344e-02 | 1.068 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 8.544344e-02 | 1.068 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.259673e-01 | 0.900 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.259673e-01 | 0.900 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects | R-HSA-9646304 | 1.259673e-01 | 0.900 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p14ARF Defects | R-HSA-9646303 | 1.259673e-01 | 0.900 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 1.020884e-01 | 0.991 | 0 | 0 |
| Diseases of cellular response to stress | R-HSA-9675132 | 1.020884e-01 | 0.991 | 0 | 0 |
| Diseases of Cellular Senescence | R-HSA-9630747 | 1.020884e-01 | 0.991 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 1.020884e-01 | 0.991 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 1.465157e-01 | 0.834 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 1.465157e-01 | 0.834 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.465157e-01 | 0.834 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 1.465157e-01 | 0.834 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 9.496360e-02 | 1.022 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 9.496360e-02 | 1.022 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 1.230118e-01 | 0.910 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 1.230118e-01 | 0.910 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 1.230118e-01 | 0.910 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.007681e-01 | 0.997 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 1.007681e-01 | 0.997 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 1.536393e-01 | 0.813 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 1.536393e-01 | 0.813 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 1.536393e-01 | 0.813 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 1.536393e-01 | 0.813 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 1.536393e-01 | 0.813 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 1.226393e-01 | 0.911 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 9.871358e-02 | 1.006 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 1.463289e-01 | 0.835 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.463289e-01 | 0.835 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 1.165913e-01 | 0.933 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 1.165913e-01 | 0.933 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 9.381921e-02 | 1.028 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 8.790727e-02 | 1.056 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 1.358821e-01 | 0.867 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 1.716238e-01 | 0.765 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 1.716238e-01 | 0.765 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 1.716238e-01 | 0.765 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 1.716238e-01 | 0.765 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 1.716238e-01 | 0.765 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 1.716238e-01 | 0.765 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 1.716238e-01 | 0.765 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 1.564796e-01 | 0.806 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.564796e-01 | 0.806 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 1.564796e-01 | 0.806 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 1.422878e-01 | 0.847 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.422878e-01 | 0.847 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 1.293397e-01 | 0.888 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.605868e-01 | 0.794 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 1.605868e-01 | 0.794 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 1.184412e-01 | 0.926 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 1.585753e-01 | 0.800 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 1.156278e-01 | 0.937 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 1.610280e-01 | 0.793 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 1.315286e-01 | 0.881 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 1.527588e-01 | 0.816 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 1.605902e-01 | 0.794 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 1.189439e-01 | 0.925 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 1.250172e-01 | 0.903 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 9.116389e-02 | 1.040 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.716238e-01 | 0.765 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 1.007681e-01 | 0.997 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 1.145827e-01 | 0.941 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.700808e-01 | 0.769 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.165913e-01 | 0.933 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 8.947120e-02 | 1.048 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 1.007681e-01 | 0.997 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 1.165913e-01 | 0.933 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 1.353389e-01 | 0.869 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 1.070747e-01 | 0.970 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 1.666040e-01 | 0.778 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 1.165913e-01 | 0.933 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 1.422878e-01 | 0.847 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 1.311988e-01 | 0.882 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 1.252630e-01 | 0.902 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.463289e-01 | 0.835 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 1.165913e-01 | 0.933 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 1.088422e-01 | 0.963 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.449951e-01 | 0.839 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 1.165913e-01 | 0.933 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 1.358821e-01 | 0.867 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.564796e-01 | 0.806 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 1.558791e-01 | 0.807 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 1.250172e-01 | 0.903 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 1.430390e-01 | 0.845 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 1.226393e-01 | 0.911 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 1.250172e-01 | 0.903 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 9.679271e-02 | 1.014 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.564796e-01 | 0.806 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 1.007620e-01 | 0.997 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 1.048217e-01 | 0.980 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 1.692704e-01 | 0.771 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 1.465157e-01 | 0.834 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 1.536393e-01 | 0.813 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 1.716238e-01 | 0.765 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 9.288956e-02 | 1.032 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 1.048553e-01 | 0.979 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 9.356688e-02 | 1.029 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.893682e-02 | 1.051 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.679271e-02 | 1.014 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 1.137456e-01 | 0.944 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 1.605902e-01 | 0.794 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 9.264726e-02 | 1.033 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 1.311988e-01 | 0.882 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 1.261186e-01 | 0.899 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 1.230118e-01 | 0.910 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 1.536393e-01 | 0.813 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 1.172315e-01 | 0.931 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 9.381921e-02 | 1.028 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 1.209284e-01 | 0.917 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 1.422878e-01 | 0.847 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 1.463289e-01 | 0.835 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 9.381921e-02 | 1.028 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 1.145827e-01 | 0.941 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 1.088422e-01 | 0.963 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 8.588797e-02 | 1.066 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.096825e-01 | 0.960 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 1.165913e-01 | 0.933 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 1.165913e-01 | 0.933 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.755711e-02 | 1.011 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 1.605902e-01 | 0.794 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 9.560269e-02 | 1.020 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 9.381921e-02 | 1.028 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 1.583990e-01 | 0.800 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 9.871358e-02 | 1.006 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 1.226393e-01 | 0.911 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 1.463289e-01 | 0.835 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.358821e-01 | 0.867 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 9.770030e-02 | 1.010 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 1.164683e-01 | 0.934 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 1.716238e-01 | 0.765 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 1.250172e-01 | 0.903 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 1.250172e-01 | 0.903 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 1.358821e-01 | 0.867 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 1.716238e-01 | 0.765 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 1.730487e-01 | 0.762 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 1.763451e-01 | 0.754 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.788117e-01 | 0.748 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.788117e-01 | 0.748 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 1.788117e-01 | 0.748 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 1.798377e-01 | 0.745 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 1.808506e-01 | 0.743 | 1 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 1.831891e-01 | 0.737 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 1.863464e-01 | 0.730 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 1.863464e-01 | 0.730 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 1.863464e-01 | 0.730 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 1.863464e-01 | 0.730 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 1.881045e-01 | 0.726 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 1.881045e-01 | 0.726 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 1.907033e-01 | 0.720 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 1.927517e-01 | 0.715 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 1.940014e-01 | 0.712 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 1.940014e-01 | 0.712 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.940014e-01 | 0.712 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.940014e-01 | 0.712 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 1.940014e-01 | 0.712 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 1.940014e-01 | 0.712 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 1.940014e-01 | 0.712 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 1.940014e-01 | 0.712 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 1.940014e-01 | 0.712 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.940014e-01 | 0.712 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 1.982968e-01 | 0.703 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.982968e-01 | 0.703 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 1.982968e-01 | 0.703 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 1.982968e-01 | 0.703 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 1.982968e-01 | 0.703 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 1.982968e-01 | 0.703 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 1.999564e-01 | 0.699 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.011036e-01 | 0.697 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 2.011036e-01 | 0.697 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 2.011036e-01 | 0.697 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 2.037083e-01 | 0.691 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 2.118980e-01 | 0.674 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 2.118980e-01 | 0.674 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 2.118980e-01 | 0.674 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 2.118980e-01 | 0.674 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 2.118980e-01 | 0.674 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 2.155930e-01 | 0.666 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 2.155930e-01 | 0.666 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 2.155930e-01 | 0.666 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.206434e-01 | 0.656 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 2.206434e-01 | 0.656 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 2.206434e-01 | 0.656 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 2.206434e-01 | 0.656 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 2.206434e-01 | 0.656 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 2.206434e-01 | 0.656 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 2.208527e-01 | 0.656 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 2.219522e-01 | 0.654 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 2.235894e-01 | 0.651 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 2.248622e-01 | 0.648 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 2.248622e-01 | 0.648 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 2.248622e-01 | 0.648 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.255891e-01 | 0.647 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 2.261142e-01 | 0.646 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 2.261142e-01 | 0.646 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 2.261142e-01 | 0.646 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.273330e-01 | 0.643 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 2.273330e-01 | 0.643 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 2.278327e-01 | 0.642 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 2.343151e-01 | 0.630 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 2.346720e-01 | 0.630 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 2.360732e-01 | 0.627 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 2.360732e-01 | 0.627 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.360732e-01 | 0.627 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.360732e-01 | 0.627 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 2.360732e-01 | 0.627 | 0 | 0 |
| RPIA deficiency: failed conversion of R5P to RU5P | R-HSA-5659996 | 2.360732e-01 | 0.627 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9630791 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH3 | R-HSA-5632927 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 2.360732e-01 | 0.627 | 0 | 0 |
| SARS-CoV-1 targets PDZ proteins in cell-cell junction | R-HSA-9692912 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.360732e-01 | 0.627 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 2.360732e-01 | 0.627 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 | R-HSA-9632697 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function | R-HSA-9645722 | 2.360732e-01 | 0.627 | 0 | 0 |
| RPIA deficiency: failed conversion of RU5P to R5P | R-HSA-6791461 | 2.360732e-01 | 0.627 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.360732e-01 | 0.627 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 2.360732e-01 | 0.627 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 2.364075e-01 | 0.626 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 2.386150e-01 | 0.622 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 2.401847e-01 | 0.619 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 2.424323e-01 | 0.615 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 2.424323e-01 | 0.615 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.430709e-01 | 0.614 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 2.430709e-01 | 0.614 | 0 | 0 |
| Toxicity of botulinum toxin type G (botG) | R-HSA-5250989 | 2.430709e-01 | 0.614 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 2.430709e-01 | 0.614 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 2.430709e-01 | 0.614 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.476769e-01 | 0.606 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 2.493977e-01 | 0.603 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 2.507387e-01 | 0.601 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 2.546856e-01 | 0.594 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 2.548211e-01 | 0.594 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 2.548211e-01 | 0.594 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 2.548416e-01 | 0.594 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 2.548416e-01 | 0.594 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 2.560654e-01 | 0.592 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 2.560654e-01 | 0.592 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 2.560654e-01 | 0.592 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 2.560654e-01 | 0.592 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 2.560654e-01 | 0.592 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 2.639293e-01 | 0.579 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 2.645977e-01 | 0.577 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 2.645977e-01 | 0.577 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 2.645977e-01 | 0.577 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.708192e-01 | 0.567 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 2.745667e-01 | 0.561 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.745667e-01 | 0.561 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 2.745667e-01 | 0.561 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 2.745667e-01 | 0.561 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 2.745667e-01 | 0.561 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 2.745667e-01 | 0.561 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 2.751770e-01 | 0.560 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 2.751770e-01 | 0.560 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 2.828465e-01 | 0.548 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 2.828465e-01 | 0.548 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 2.842495e-01 | 0.546 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 2.842495e-01 | 0.546 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 2.842495e-01 | 0.546 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 2.872503e-01 | 0.542 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 2.872503e-01 | 0.542 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 2.872503e-01 | 0.542 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 2.872503e-01 | 0.542 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 2.872503e-01 | 0.542 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 2.910939e-01 | 0.536 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 2.921821e-01 | 0.534 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 2.921821e-01 | 0.534 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 2.921821e-01 | 0.534 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 2.921821e-01 | 0.534 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 2.921821e-01 | 0.534 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 2.925723e-01 | 0.534 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 2.925723e-01 | 0.534 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 2.925723e-01 | 0.534 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 2.925723e-01 | 0.534 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 2.925723e-01 | 0.534 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 2.925723e-01 | 0.534 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 2.925723e-01 | 0.534 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 2.925723e-01 | 0.534 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 2.925723e-01 | 0.534 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 2.925723e-01 | 0.534 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 2.928836e-01 | 0.533 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 2.959303e-01 | 0.529 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 2.959303e-01 | 0.529 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 3.002271e-01 | 0.523 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 3.002271e-01 | 0.523 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 3.002271e-01 | 0.523 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 3.006861e-01 | 0.522 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 3.021007e-01 | 0.520 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.021007e-01 | 0.520 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 3.021007e-01 | 0.520 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 3.032721e-01 | 0.518 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 3.046209e-01 | 0.516 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 3.065892e-01 | 0.513 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 3.098939e-01 | 0.509 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 3.102911e-01 | 0.508 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 3.141167e-01 | 0.503 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 3.141167e-01 | 0.503 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 3.170877e-01 | 0.499 | 1 | 1 |
| Gastrulation | R-HSA-9758941 | 3.243404e-01 | 0.489 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 3.262396e-01 | 0.486 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 3.286038e-01 | 0.483 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 3.286038e-01 | 0.483 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 3.286038e-01 | 0.483 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 3.286038e-01 | 0.483 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 3.286038e-01 | 0.483 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 3.286038e-01 | 0.483 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 3.286038e-01 | 0.483 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 3.296969e-01 | 0.482 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects | R-HSA-9632693 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.323142e-01 | 0.478 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to p16INK4A Defects | R-HSA-9630750 | 3.323142e-01 | 0.478 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 3.323142e-01 | 0.478 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.323142e-01 | 0.478 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.323142e-01 | 0.478 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 3.323142e-01 | 0.478 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 3.323142e-01 | 0.478 | 0 | 0 |
| Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9630794 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective SLC17A5 causes Salla disease (SD) and ISSD | R-HSA-5619035 | 3.323142e-01 | 0.478 | 0 | 0 |
| Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 | R-HSA-9632700 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.323142e-01 | 0.478 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 3.323142e-01 | 0.478 | 0 | 0 |
| Inhibition of Host mRNA Processing and RNA Silencing | R-HSA-168315 | 3.323142e-01 | 0.478 | 0 | 0 |
| Transport of connexins along the secretory pathway | R-HSA-190827 | 3.323142e-01 | 0.478 | 0 | 0 |
| Defective SERPING1 causes hereditary angioedema | R-HSA-9657689 | 3.323142e-01 | 0.478 | 0 | 0 |
| Oligomerization of connexins into connexons | R-HSA-190704 | 3.323142e-01 | 0.478 | 0 | 0 |
| NTRK3 as a dependence receptor | R-HSA-9603505 | 3.323142e-01 | 0.478 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 3.336225e-01 | 0.477 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 3.336225e-01 | 0.477 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 3.336225e-01 | 0.477 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 3.336225e-01 | 0.477 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 3.348249e-01 | 0.475 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 3.371421e-01 | 0.472 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 3.416185e-01 | 0.466 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 3.416185e-01 | 0.466 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 3.416185e-01 | 0.466 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 3.416185e-01 | 0.466 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 3.416185e-01 | 0.466 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 3.416185e-01 | 0.466 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 3.416185e-01 | 0.466 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 3.442342e-01 | 0.463 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 3.442342e-01 | 0.463 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.442342e-01 | 0.463 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 3.442342e-01 | 0.463 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 3.442342e-01 | 0.463 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 3.442342e-01 | 0.463 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 3.451912e-01 | 0.462 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 3.524696e-01 | 0.453 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 3.524696e-01 | 0.453 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 3.571488e-01 | 0.447 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 3.571488e-01 | 0.447 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 3.598402e-01 | 0.444 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 3.613113e-01 | 0.442 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 3.618436e-01 | 0.441 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 3.621078e-01 | 0.441 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 3.649840e-01 | 0.438 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 3.649840e-01 | 0.438 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 3.744073e-01 | 0.427 | 0 | 0 |
| PKA activation | R-HSA-163615 | 3.744073e-01 | 0.427 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 3.744073e-01 | 0.427 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 3.744073e-01 | 0.427 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 3.744073e-01 | 0.427 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 3.744073e-01 | 0.427 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 3.786013e-01 | 0.422 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 3.787887e-01 | 0.422 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 3.895391e-01 | 0.409 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 3.895391e-01 | 0.409 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 3.895391e-01 | 0.409 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 3.895391e-01 | 0.409 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 3.895391e-01 | 0.409 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.895391e-01 | 0.409 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 3.895391e-01 | 0.409 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 3.895391e-01 | 0.409 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 3.895391e-01 | 0.409 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 4.010204e-01 | 0.397 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.010204e-01 | 0.397 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 4.044199e-01 | 0.393 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 4.044569e-01 | 0.393 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 4.044569e-01 | 0.393 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 4.050759e-01 | 0.392 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 4.050759e-01 | 0.392 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 4.050759e-01 | 0.392 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 4.074119e-01 | 0.390 | 0 | 0 |
| RUNX3 regulates RUNX1-mediated transcription | R-HSA-8951911 | 4.164354e-01 | 0.380 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 4.164354e-01 | 0.380 | 0 | 0 |
| Defective AHCY causes HMAHCHD | R-HSA-5578997 | 4.164354e-01 | 0.380 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 4.164354e-01 | 0.380 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 4.164354e-01 | 0.380 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 4.164354e-01 | 0.380 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 4.164354e-01 | 0.380 | 0 | 0 |
| Defective ABCC8 can cause hypo- and hyper-glycemias | R-HSA-5683177 | 4.164354e-01 | 0.380 | 0 | 0 |
| Defective factor XII causes hereditary angioedema | R-HSA-9657688 | 4.164354e-01 | 0.380 | 0 | 0 |
| Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization | R-HSA-180897 | 4.164354e-01 | 0.380 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 4.164354e-01 | 0.380 | 0 | 0 |
| Signalling to ERK5 | R-HSA-198765 | 4.164354e-01 | 0.380 | 0 | 0 |
| tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis | R-HSA-9708296 | 4.164354e-01 | 0.380 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 4.164354e-01 | 0.380 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 4.215101e-01 | 0.375 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 4.247312e-01 | 0.372 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 4.247312e-01 | 0.372 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 4.247312e-01 | 0.372 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 4.279920e-01 | 0.369 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 4.287811e-01 | 0.368 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 4.287811e-01 | 0.368 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 4.297610e-01 | 0.367 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 4.312182e-01 | 0.365 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 4.312182e-01 | 0.365 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 4.342210e-01 | 0.362 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 4.342210e-01 | 0.362 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 4.358394e-01 | 0.361 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 4.358394e-01 | 0.361 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 4.358394e-01 | 0.361 | 0 | 0 |
| Toxicity of botulinum toxin type B (botB) | R-HSA-5250958 | 4.358394e-01 | 0.361 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 4.358394e-01 | 0.361 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 4.358394e-01 | 0.361 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 4.358394e-01 | 0.361 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 4.358394e-01 | 0.361 | 0 | 0 |
| RSK activation | R-HSA-444257 | 4.358394e-01 | 0.361 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 4.358394e-01 | 0.361 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 4.364543e-01 | 0.360 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 4.364543e-01 | 0.360 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 4.364543e-01 | 0.360 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 4.415451e-01 | 0.355 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 4.415451e-01 | 0.355 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 4.462675e-01 | 0.350 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 4.462675e-01 | 0.350 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 4.462675e-01 | 0.350 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 4.467070e-01 | 0.350 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 4.571116e-01 | 0.340 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 4.571116e-01 | 0.340 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 4.571116e-01 | 0.340 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 4.571116e-01 | 0.340 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 4.571116e-01 | 0.340 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 4.635551e-01 | 0.334 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 4.635551e-01 | 0.334 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 4.635551e-01 | 0.334 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 4.714757e-01 | 0.327 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 4.746136e-01 | 0.324 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 4.801672e-01 | 0.319 | 0 | 0 |
| Hypusine synthesis from eIF5A-lysine | R-HSA-204626 | 4.801672e-01 | 0.319 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 4.801672e-01 | 0.319 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 4.801672e-01 | 0.319 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 4.801672e-01 | 0.319 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 4.801672e-01 | 0.319 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 4.801672e-01 | 0.319 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 4.801672e-01 | 0.319 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 4.801672e-01 | 0.319 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 4.801672e-01 | 0.319 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 4.801672e-01 | 0.319 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 4.801672e-01 | 0.319 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 4.801672e-01 | 0.319 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 4.826613e-01 | 0.316 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 4.826613e-01 | 0.316 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 4.826613e-01 | 0.316 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 4.888391e-01 | 0.311 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 4.888391e-01 | 0.311 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 4.899625e-01 | 0.310 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 4.899625e-01 | 0.310 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 4.899625e-01 | 0.310 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 4.899625e-01 | 0.310 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 4.899625e-01 | 0.310 | 0 | 0 |
| Signalling to STAT3 | R-HSA-198745 | 4.899625e-01 | 0.310 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.899625e-01 | 0.310 | 0 | 0 |
| Classical Kir channels | R-HSA-1296053 | 4.899625e-01 | 0.310 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.899625e-01 | 0.310 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 4.899625e-01 | 0.310 | 0 | 0 |
| Activation of BMF and translocation to mitochondria | R-HSA-139910 | 4.899625e-01 | 0.310 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 4.899625e-01 | 0.310 | 0 | 0 |
| CASP5-mediated substrate cleavage | R-HSA-9960525 | 4.899625e-01 | 0.310 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 4.899625e-01 | 0.310 | 0 | 0 |
| CASP4-mediated substrate cleavage | R-HSA-9960519 | 4.899625e-01 | 0.310 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 4.923318e-01 | 0.308 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 4.923318e-01 | 0.308 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 4.923318e-01 | 0.308 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 5.028721e-01 | 0.299 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 5.046829e-01 | 0.297 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 5.046829e-01 | 0.297 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 5.046829e-01 | 0.297 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.077819e-01 | 0.294 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 5.077819e-01 | 0.294 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 5.097670e-01 | 0.293 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 5.097670e-01 | 0.293 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 5.113442e-01 | 0.291 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.127000e-01 | 0.290 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 5.200758e-01 | 0.284 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 5.200758e-01 | 0.284 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 5.200758e-01 | 0.284 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 5.204411e-01 | 0.284 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 5.204411e-01 | 0.284 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 5.204411e-01 | 0.284 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 5.204411e-01 | 0.284 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 5.204411e-01 | 0.284 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 5.222846e-01 | 0.282 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 5.222846e-01 | 0.282 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 5.222846e-01 | 0.282 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 5.222846e-01 | 0.282 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 5.222846e-01 | 0.282 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 5.222846e-01 | 0.282 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 5.287325e-01 | 0.277 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 5.289098e-01 | 0.277 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 5.323974e-01 | 0.274 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 5.360940e-01 | 0.271 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 5.366961e-01 | 0.270 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 5.371559e-01 | 0.270 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 5.371559e-01 | 0.270 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) | R-HSA-400511 | 5.371559e-01 | 0.270 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 5.371559e-01 | 0.270 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 5.371559e-01 | 0.270 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 5.402053e-01 | 0.267 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 5.473159e-01 | 0.262 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 5.477894e-01 | 0.261 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 5.529878e-01 | 0.257 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 5.542292e-01 | 0.256 | 0 | 0 |
| Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine | R-HSA-9735763 | 5.542292e-01 | 0.256 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 5.542292e-01 | 0.256 | 0 | 0 |
| Nucleotide catabolism defects | R-HSA-9735786 | 5.542292e-01 | 0.256 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 5.542292e-01 | 0.256 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 5.542292e-01 | 0.256 | 0 | 0 |
| Defective MAT1A causes MATD | R-HSA-5579024 | 5.542292e-01 | 0.256 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 5.542292e-01 | 0.256 | 0 | 0 |
| Defective LFNG causes SCDO3 | R-HSA-5083630 | 5.542292e-01 | 0.256 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 5.542292e-01 | 0.256 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 5.542292e-01 | 0.256 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 5.542292e-01 | 0.256 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.542292e-01 | 0.256 | 0 | 0 |
| Toxicity of tetanus toxin (tetX) | R-HSA-5250982 | 5.542292e-01 | 0.256 | 0 | 0 |
| Interleukin-38 signaling | R-HSA-9007892 | 5.542292e-01 | 0.256 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 5.611336e-01 | 0.251 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 5.620450e-01 | 0.250 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 5.620450e-01 | 0.250 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 5.620450e-01 | 0.250 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 5.620450e-01 | 0.250 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 5.620450e-01 | 0.250 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 5.620450e-01 | 0.250 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 5.639057e-01 | 0.249 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 5.649113e-01 | 0.248 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 5.683765e-01 | 0.245 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 5.705601e-01 | 0.244 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 5.742990e-01 | 0.241 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 5.742990e-01 | 0.241 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 5.798565e-01 | 0.237 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 5.850869e-01 | 0.233 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 5.850869e-01 | 0.233 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 5.874294e-01 | 0.231 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 5.969854e-01 | 0.224 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 5.982629e-01 | 0.223 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 5.982629e-01 | 0.223 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 5.983966e-01 | 0.223 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 5.991887e-01 | 0.222 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 5.993737e-01 | 0.222 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 5.993737e-01 | 0.222 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 5.993737e-01 | 0.222 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 5.993737e-01 | 0.222 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 5.999069e-01 | 0.222 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 5.999069e-01 | 0.222 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 5.999069e-01 | 0.222 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 6.014760e-01 | 0.221 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 6.015201e-01 | 0.221 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 6.025942e-01 | 0.220 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 6.034611e-01 | 0.219 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 6.056294e-01 | 0.218 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 6.057258e-01 | 0.218 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 6.057258e-01 | 0.218 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 6.057258e-01 | 0.218 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 6.075584e-01 | 0.216 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 6.090463e-01 | 0.215 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 6.104013e-01 | 0.214 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 6.104013e-01 | 0.214 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 6.104013e-01 | 0.214 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 6.104013e-01 | 0.214 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 6.104013e-01 | 0.214 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 6.104013e-01 | 0.214 | 0 | 0 |
| Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) | R-HSA-5619067 | 6.104013e-01 | 0.214 | 0 | 0 |
| PTK6 Activates STAT3 | R-HSA-8849474 | 6.104013e-01 | 0.214 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 6.104013e-01 | 0.214 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 6.104013e-01 | 0.214 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 6.104013e-01 | 0.214 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 6.104013e-01 | 0.214 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 6.104013e-01 | 0.214 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 6.104013e-01 | 0.214 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 6.104013e-01 | 0.214 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 6.104013e-01 | 0.214 | 0 | 0 |
| Reelin signalling pathway | R-HSA-8866376 | 6.104013e-01 | 0.214 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 6.104013e-01 | 0.214 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 6.104013e-01 | 0.214 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 6.104013e-01 | 0.214 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 6.124336e-01 | 0.213 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 6.152969e-01 | 0.211 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 6.152969e-01 | 0.211 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 6.225178e-01 | 0.206 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 6.245637e-01 | 0.204 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 6.245637e-01 | 0.204 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.257579e-01 | 0.204 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 6.267588e-01 | 0.203 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 6.267588e-01 | 0.203 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 6.267588e-01 | 0.203 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 6.267588e-01 | 0.203 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 6.342521e-01 | 0.198 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 6.342521e-01 | 0.198 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 6.342521e-01 | 0.198 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 6.342521e-01 | 0.198 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 6.345894e-01 | 0.198 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 6.452512e-01 | 0.190 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 6.452512e-01 | 0.190 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 6.452512e-01 | 0.190 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 6.452512e-01 | 0.190 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 6.458848e-01 | 0.190 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 6.458848e-01 | 0.190 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 6.466043e-01 | 0.189 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 6.482330e-01 | 0.188 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 6.482330e-01 | 0.188 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 6.594979e-01 | 0.181 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 6.594979e-01 | 0.181 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 6.594979e-01 | 0.181 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.594979e-01 | 0.181 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.594979e-01 | 0.181 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 6.594979e-01 | 0.181 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.594979e-01 | 0.181 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 6.594979e-01 | 0.181 | 0 | 0 |
| Loss-of-function mutations in DBT cause MSUD2 | R-HSA-9865113 | 6.594979e-01 | 0.181 | 0 | 0 |
| Loss-of-function mutations in DLD cause MSUD3/DLDD | R-HSA-9907570 | 6.594979e-01 | 0.181 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 6.594979e-01 | 0.181 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 6.594979e-01 | 0.181 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 6.594979e-01 | 0.181 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.594979e-01 | 0.181 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 6.594979e-01 | 0.181 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 6.594979e-01 | 0.181 | 0 | 0 |
| Acetylcholine inhibits contraction of outer hair cells | R-HSA-9667769 | 6.594979e-01 | 0.181 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 6.594979e-01 | 0.181 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 6.594979e-01 | 0.181 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 6.594979e-01 | 0.181 | 0 | 0 |
| Epithelial-Mesenchymal Transition (EMT) during gastrulation | R-HSA-9758919 | 6.594979e-01 | 0.181 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.594979e-01 | 0.181 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 6.663807e-01 | 0.176 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 6.663807e-01 | 0.176 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 6.667050e-01 | 0.176 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 6.667050e-01 | 0.176 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 6.667050e-01 | 0.176 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 6.667050e-01 | 0.176 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 6.667050e-01 | 0.176 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 6.667050e-01 | 0.176 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 6.708896e-01 | 0.173 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 6.708896e-01 | 0.173 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 6.708896e-01 | 0.173 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 6.785913e-01 | 0.168 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 6.794631e-01 | 0.168 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 6.822833e-01 | 0.166 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 6.847077e-01 | 0.164 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 6.860845e-01 | 0.164 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 6.860845e-01 | 0.164 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 6.925187e-01 | 0.160 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 6.965236e-01 | 0.157 | 0 | 0 |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA | R-HSA-77348 | 6.967898e-01 | 0.157 | 0 | 0 |
| Beta oxidation of hexanoyl-CoA to butanoyl-CoA | R-HSA-77350 | 6.967898e-01 | 0.157 | 0 | 0 |
| Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA | R-HSA-77310 | 6.967898e-01 | 0.157 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 6.967898e-01 | 0.157 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 6.967898e-01 | 0.157 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 6.967898e-01 | 0.157 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 6.967898e-01 | 0.157 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 6.967898e-01 | 0.157 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 6.967898e-01 | 0.157 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 6.967898e-01 | 0.157 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 6.998239e-01 | 0.155 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 7.024100e-01 | 0.153 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 7.024100e-01 | 0.153 | 0 | 0 |
| Loss-of-function mutations in BCKDHA or BCKDHB cause MSUD | R-HSA-9865125 | 7.024100e-01 | 0.153 | 0 | 0 |
| H139Hfs13* PPM1K causes a mild variant of MSUD | R-HSA-9912529 | 7.024100e-01 | 0.153 | 0 | 0 |
| Branched-chain ketoacid dehydrogenase kinase deficiency | R-HSA-9912481 | 7.024100e-01 | 0.153 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 7.024100e-01 | 0.153 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 7.024100e-01 | 0.153 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 7.024100e-01 | 0.153 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 7.024100e-01 | 0.153 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 7.024100e-01 | 0.153 | 0 | 0 |
| Leukotriene receptors | R-HSA-391906 | 7.024100e-01 | 0.153 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 7.024100e-01 | 0.153 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 7.024100e-01 | 0.153 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 7.036584e-01 | 0.153 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 7.036584e-01 | 0.153 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 7.094618e-01 | 0.149 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 7.094618e-01 | 0.149 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 7.096130e-01 | 0.149 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 7.096130e-01 | 0.149 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 7.096130e-01 | 0.149 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 7.123858e-01 | 0.147 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 7.131147e-01 | 0.147 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 7.167015e-01 | 0.145 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 7.239694e-01 | 0.140 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 7.245878e-01 | 0.140 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 7.245878e-01 | 0.140 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 7.245878e-01 | 0.140 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 7.245878e-01 | 0.140 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 7.245878e-01 | 0.140 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 7.250109e-01 | 0.140 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.264318e-01 | 0.139 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 7.264318e-01 | 0.139 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 7.264318e-01 | 0.139 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 7.326802e-01 | 0.135 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 7.329116e-01 | 0.135 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 7.329116e-01 | 0.135 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 7.399161e-01 | 0.131 | 0 | 0 |
| Pre-NOTCH Processing in the Endoplasmic Reticulum | R-HSA-1912399 | 7.399161e-01 | 0.131 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.399161e-01 | 0.131 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 7.399161e-01 | 0.131 | 0 | 0 |
| Opsins | R-HSA-419771 | 7.399161e-01 | 0.131 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 7.399161e-01 | 0.131 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 7.399161e-01 | 0.131 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 7.399161e-01 | 0.131 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 7.399161e-01 | 0.131 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 7.399161e-01 | 0.131 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.399161e-01 | 0.131 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 7.399161e-01 | 0.131 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 7.399161e-01 | 0.131 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 7.399161e-01 | 0.131 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 7.399161e-01 | 0.131 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 7.399161e-01 | 0.131 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 7.403563e-01 | 0.131 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.478098e-01 | 0.126 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 7.479714e-01 | 0.126 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 7.501974e-01 | 0.125 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 7.501974e-01 | 0.125 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 7.501974e-01 | 0.125 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 7.501974e-01 | 0.125 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 7.501974e-01 | 0.125 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 7.501974e-01 | 0.125 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 7.501974e-01 | 0.125 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 7.501974e-01 | 0.125 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 7.506025e-01 | 0.125 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 7.514974e-01 | 0.124 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 7.528356e-01 | 0.123 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 7.568317e-01 | 0.121 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 7.645152e-01 | 0.117 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.678286e-01 | 0.115 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 7.691767e-01 | 0.114 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 7.701540e-01 | 0.113 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 7.726972e-01 | 0.112 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 7.726972e-01 | 0.112 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 7.726972e-01 | 0.112 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.726972e-01 | 0.112 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 7.726972e-01 | 0.112 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 7.726972e-01 | 0.112 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 7.726972e-01 | 0.112 | 0 | 0 |
| Fructose biosynthesis | R-HSA-5652227 | 7.726972e-01 | 0.112 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.726972e-01 | 0.112 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 7.726972e-01 | 0.112 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 7.726972e-01 | 0.112 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 7.726972e-01 | 0.112 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 7.726972e-01 | 0.112 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 7.737288e-01 | 0.111 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 7.737288e-01 | 0.111 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 7.737288e-01 | 0.111 | 0 | 0 |
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA | R-HSA-77346 | 7.737288e-01 | 0.111 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 7.737288e-01 | 0.111 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 7.737288e-01 | 0.111 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.737288e-01 | 0.111 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 7.737288e-01 | 0.111 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 7.737288e-01 | 0.111 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 7.831780e-01 | 0.106 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 7.865312e-01 | 0.104 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 7.865312e-01 | 0.104 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 7.865312e-01 | 0.104 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 7.865312e-01 | 0.104 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 7.865312e-01 | 0.104 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 7.865312e-01 | 0.104 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 7.911061e-01 | 0.102 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 7.911061e-01 | 0.102 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 7.952987e-01 | 0.099 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 7.952987e-01 | 0.099 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 7.952987e-01 | 0.099 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 7.952987e-01 | 0.099 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 7.952987e-01 | 0.099 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 7.956434e-01 | 0.099 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 8.009137e-01 | 0.096 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 8.009137e-01 | 0.096 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 8.009137e-01 | 0.096 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 8.013482e-01 | 0.096 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 8.013482e-01 | 0.096 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 8.013482e-01 | 0.096 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 8.013482e-01 | 0.096 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 8.013482e-01 | 0.096 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 8.013482e-01 | 0.096 | 0 | 0 |
| Expression of NOTCH2NL genes | R-HSA-9911233 | 8.013482e-01 | 0.096 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 8.013482e-01 | 0.096 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 8.013482e-01 | 0.096 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 8.013482e-01 | 0.096 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 8.013482e-01 | 0.096 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 8.015260e-01 | 0.096 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 8.039665e-01 | 0.095 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.039665e-01 | 0.095 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 8.039665e-01 | 0.095 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 8.065766e-01 | 0.093 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 8.075579e-01 | 0.093 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.075579e-01 | 0.093 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 8.150278e-01 | 0.089 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 8.150278e-01 | 0.089 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 8.150278e-01 | 0.089 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 8.150278e-01 | 0.089 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 8.150278e-01 | 0.089 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 8.201874e-01 | 0.086 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 8.201874e-01 | 0.086 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 8.206648e-01 | 0.086 | 0 | 0 |
| TET1,2,3 and TDG demethylate DNA | R-HSA-5221030 | 8.263893e-01 | 0.083 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 8.263893e-01 | 0.083 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 8.263893e-01 | 0.083 | 0 | 0 |
| Metabolism of serotonin | R-HSA-380612 | 8.263893e-01 | 0.083 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 8.263893e-01 | 0.083 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 8.263893e-01 | 0.083 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 8.263893e-01 | 0.083 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 8.297728e-01 | 0.081 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 8.330373e-01 | 0.079 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 8.330373e-01 | 0.079 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 8.330373e-01 | 0.079 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 8.352499e-01 | 0.078 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 8.390297e-01 | 0.076 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 8.422423e-01 | 0.075 | 0 | 0 |
| Conjugation of benzoate with glycine | R-HSA-177135 | 8.482751e-01 | 0.071 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 8.482751e-01 | 0.071 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 8.482751e-01 | 0.071 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 8.482751e-01 | 0.071 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 8.482751e-01 | 0.071 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 8.482751e-01 | 0.071 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 8.482751e-01 | 0.071 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 8.482751e-01 | 0.071 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 8.482751e-01 | 0.071 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 8.494471e-01 | 0.071 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 8.494471e-01 | 0.071 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 8.494471e-01 | 0.071 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 8.494471e-01 | 0.071 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 8.494471e-01 | 0.071 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 8.494471e-01 | 0.071 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 8.494471e-01 | 0.071 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 8.494471e-01 | 0.071 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 8.505416e-01 | 0.070 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 8.507066e-01 | 0.070 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 8.507066e-01 | 0.070 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 8.538052e-01 | 0.069 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 8.543110e-01 | 0.068 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 8.556128e-01 | 0.068 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 8.564432e-01 | 0.067 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 8.564432e-01 | 0.067 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 8.600241e-01 | 0.065 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 8.621312e-01 | 0.064 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 8.643743e-01 | 0.063 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 8.643743e-01 | 0.063 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 8.674030e-01 | 0.062 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 8.674030e-01 | 0.062 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 8.674030e-01 | 0.062 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 8.674030e-01 | 0.062 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.674030e-01 | 0.062 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 8.674030e-01 | 0.062 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.740672e-01 | 0.058 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 8.779319e-01 | 0.057 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 8.779319e-01 | 0.057 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 8.781048e-01 | 0.056 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 8.805636e-01 | 0.055 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 8.814663e-01 | 0.055 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 8.838711e-01 | 0.054 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 8.841204e-01 | 0.053 | 0 | 0 |
| Maple Syrup Urine Disease | R-HSA-9865114 | 8.841204e-01 | 0.053 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.841204e-01 | 0.053 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 8.841204e-01 | 0.053 | 0 | 0 |
| Beta oxidation of myristoyl-CoA to lauroyl-CoA | R-HSA-77285 | 8.841204e-01 | 0.053 | 0 | 0 |
| Beta oxidation of palmitoyl-CoA to myristoyl-CoA | R-HSA-77305 | 8.841204e-01 | 0.053 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 8.841204e-01 | 0.053 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 8.841204e-01 | 0.053 | 0 | 0 |
| Conjugation of salicylate with glycine | R-HSA-177128 | 8.841204e-01 | 0.053 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 8.841204e-01 | 0.053 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.841204e-01 | 0.053 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 8.841204e-01 | 0.053 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 8.841204e-01 | 0.053 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 8.841204e-01 | 0.053 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.849380e-01 | 0.053 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 8.850781e-01 | 0.053 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 8.858991e-01 | 0.053 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 8.860484e-01 | 0.053 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 8.902278e-01 | 0.050 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 8.950129e-01 | 0.048 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 8.975046e-01 | 0.047 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 8.978186e-01 | 0.047 | 0 | 0 |
| PDH complex synthesizes acetyl-CoA from PYR | R-HSA-9861559 | 8.987310e-01 | 0.046 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 8.987310e-01 | 0.046 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 8.987310e-01 | 0.046 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 8.987310e-01 | 0.046 | 0 | 0 |
| Reversible hydration of carbon dioxide | R-HSA-1475029 | 8.987310e-01 | 0.046 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 8.987310e-01 | 0.046 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 8.998441e-01 | 0.046 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 9.013646e-01 | 0.045 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 9.013646e-01 | 0.045 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.013646e-01 | 0.045 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.013646e-01 | 0.045 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.013646e-01 | 0.045 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 9.045513e-01 | 0.044 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.045513e-01 | 0.044 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.113375e-01 | 0.040 | 0 | 0 |
| BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV | R-HSA-9859138 | 9.115002e-01 | 0.040 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 9.115002e-01 | 0.040 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 9.115002e-01 | 0.040 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 9.115002e-01 | 0.040 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 9.115002e-01 | 0.040 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 9.115002e-01 | 0.040 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 9.115002e-01 | 0.040 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 9.115002e-01 | 0.040 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 9.131234e-01 | 0.039 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.131234e-01 | 0.039 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 9.131234e-01 | 0.039 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 9.205419e-01 | 0.036 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 9.205419e-01 | 0.036 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.205419e-01 | 0.036 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.215087e-01 | 0.036 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 9.226599e-01 | 0.035 | 0 | 0 |
| Protein repair | R-HSA-5676934 | 9.226599e-01 | 0.035 | 0 | 0 |
| Beta oxidation of butanoyl-CoA to acetyl-CoA | R-HSA-77352 | 9.226599e-01 | 0.035 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 9.226599e-01 | 0.035 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 9.226599e-01 | 0.035 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 9.253617e-01 | 0.034 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.283357e-01 | 0.032 | 0 | 0 |
| Linoleic acid (LA) metabolism | R-HSA-2046105 | 9.287579e-01 | 0.032 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.287579e-01 | 0.032 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.287864e-01 | 0.032 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 9.324130e-01 | 0.030 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 9.324130e-01 | 0.030 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 9.324130e-01 | 0.030 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 9.324130e-01 | 0.030 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 9.324130e-01 | 0.030 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 9.324130e-01 | 0.030 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 9.324130e-01 | 0.030 | 0 | 0 |
| Mitochondrial Uncoupling | R-HSA-166187 | 9.324130e-01 | 0.030 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.347984e-01 | 0.029 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.369417e-01 | 0.028 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.369417e-01 | 0.028 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 9.408342e-01 | 0.026 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.408342e-01 | 0.026 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 9.409366e-01 | 0.026 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 9.409366e-01 | 0.026 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 9.409366e-01 | 0.026 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 9.409366e-01 | 0.026 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of unsaturated fatty acids | R-HSA-77288 | 9.409366e-01 | 0.026 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 9.409366e-01 | 0.026 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.409366e-01 | 0.026 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 9.426710e-01 | 0.026 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 9.428394e-01 | 0.026 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 9.428394e-01 | 0.026 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.460701e-01 | 0.024 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.460701e-01 | 0.024 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.460701e-01 | 0.024 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 9.483858e-01 | 0.023 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 9.483858e-01 | 0.023 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 9.483858e-01 | 0.023 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 9.483858e-01 | 0.023 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.484977e-01 | 0.023 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.485064e-01 | 0.023 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 9.488453e-01 | 0.023 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 9.488453e-01 | 0.023 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.488453e-01 | 0.023 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.499313e-01 | 0.022 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.499601e-01 | 0.022 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.503845e-01 | 0.022 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 9.520847e-01 | 0.021 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.542459e-01 | 0.020 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 9.542459e-01 | 0.020 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 9.542459e-01 | 0.020 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.543828e-01 | 0.020 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 9.548958e-01 | 0.020 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 9.548958e-01 | 0.020 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.548958e-01 | 0.020 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.559709e-01 | 0.020 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 9.578292e-01 | 0.019 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.590985e-01 | 0.018 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.603201e-01 | 0.018 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.605850e-01 | 0.017 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 9.605850e-01 | 0.017 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 9.605850e-01 | 0.017 | 0 | 0 |
| HDL remodeling | R-HSA-8964058 | 9.605850e-01 | 0.017 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 9.605850e-01 | 0.017 | 0 | 0 |
| Amino Acid conjugation | R-HSA-156587 | 9.605850e-01 | 0.017 | 0 | 0 |
| Conjugation of carboxylic acids | R-HSA-159424 | 9.605850e-01 | 0.017 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 9.605850e-01 | 0.017 | 0 | 0 |
| Methionine salvage pathway | R-HSA-1237112 | 9.605850e-01 | 0.017 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 9.605850e-01 | 0.017 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 9.615106e-01 | 0.017 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.655569e-01 | 0.015 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.655569e-01 | 0.015 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.655569e-01 | 0.015 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.655569e-01 | 0.015 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.656281e-01 | 0.015 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 9.673639e-01 | 0.014 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 9.673639e-01 | 0.014 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 9.673639e-01 | 0.014 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.673639e-01 | 0.014 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.697375e-01 | 0.013 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 9.699019e-01 | 0.013 | 0 | 0 |
| Phenylalanine metabolism | R-HSA-8964208 | 9.699019e-01 | 0.013 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 9.699019e-01 | 0.013 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.699019e-01 | 0.013 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.705648e-01 | 0.013 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 9.708684e-01 | 0.013 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.716028e-01 | 0.013 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 9.736990e-01 | 0.012 | 0 | 0 |
| Androgen biosynthesis | R-HSA-193048 | 9.736990e-01 | 0.012 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.740083e-01 | 0.011 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.766673e-01 | 0.010 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.768198e-01 | 0.010 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 9.768198e-01 | 0.010 | 0 | 0 |
| Metabolism of ingested SeMet, Sec, MeSec into H2Se | R-HSA-2408508 | 9.768198e-01 | 0.010 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.770173e-01 | 0.010 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.770173e-01 | 0.010 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.770173e-01 | 0.010 | 0 | 0 |
| Free fatty acid receptors | R-HSA-444209 | 9.770173e-01 | 0.010 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.770173e-01 | 0.010 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.770173e-01 | 0.010 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 9.770173e-01 | 0.010 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.771893e-01 | 0.010 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.773537e-01 | 0.010 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.776987e-01 | 0.010 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.783639e-01 | 0.009 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.791450e-01 | 0.009 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.799171e-01 | 0.009 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.799171e-01 | 0.009 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 9.804938e-01 | 0.009 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.815862e-01 | 0.008 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.815862e-01 | 0.008 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.815862e-01 | 0.008 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.820689e-01 | 0.008 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.824511e-01 | 0.008 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.824511e-01 | 0.008 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.824511e-01 | 0.008 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 9.824511e-01 | 0.008 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.833083e-01 | 0.007 | 0 | 0 |
| tRNA processing in the mitochondrion | R-HSA-6785470 | 9.835979e-01 | 0.007 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.835979e-01 | 0.007 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.835979e-01 | 0.007 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.840884e-01 | 0.007 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.846656e-01 | 0.007 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.846656e-01 | 0.007 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 9.846656e-01 | 0.007 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.860121e-01 | 0.006 | 0 | 0 |
| Diseases of branched-chain amino acid catabolism | R-HSA-9865118 | 9.866007e-01 | 0.006 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.866007e-01 | 0.006 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.870002e-01 | 0.006 | 0 | 0 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | R-HSA-83936 | 9.882917e-01 | 0.005 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.884628e-01 | 0.005 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.891103e-01 | 0.005 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.897110e-01 | 0.004 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.897110e-01 | 0.004 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.897694e-01 | 0.004 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.900160e-01 | 0.004 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.900160e-01 | 0.004 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.910607e-01 | 0.004 | 0 | 0 |
| Regulation of pyruvate dehydrogenase (PDH) complex | R-HSA-204174 | 9.910607e-01 | 0.004 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.913941e-01 | 0.004 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.924783e-01 | 0.003 | 0 | 0 |
| Methylation | R-HSA-156581 | 9.927726e-01 | 0.003 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.931750e-01 | 0.003 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids | R-HSA-77286 | 9.935791e-01 | 0.003 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.935791e-01 | 0.003 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.936312e-01 | 0.003 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.936312e-01 | 0.003 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.936312e-01 | 0.003 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.940660e-01 | 0.003 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.947894e-01 | 0.002 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.949364e-01 | 0.002 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.951258e-01 | 0.002 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.954473e-01 | 0.002 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.954473e-01 | 0.002 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.954473e-01 | 0.002 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.954473e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.955052e-01 | 0.002 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.957326e-01 | 0.002 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.960111e-01 | 0.002 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.960111e-01 | 0.002 | 0 | 0 |
| Phosphate bond hydrolysis by NUDT proteins | R-HSA-2393930 | 9.960221e-01 | 0.002 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.965244e-01 | 0.002 | 0 | 0 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 9.968608e-01 | 0.001 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.969633e-01 | 0.001 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.971113e-01 | 0.001 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.971876e-01 | 0.001 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.973468e-01 | 0.001 | 0 | 0 |
| Phenylalanine and tyrosine metabolism | R-HSA-8963691 | 9.973468e-01 | 0.001 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.973468e-01 | 0.001 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.974829e-01 | 0.001 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.974829e-01 | 0.001 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.977479e-01 | 0.001 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.978122e-01 | 0.001 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.982304e-01 | 0.001 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.982304e-01 | 0.001 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.982304e-01 | 0.001 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.984539e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.986492e-01 | 0.001 | 0 | 0 |
| Heme biosynthesis | R-HSA-189451 | 9.986492e-01 | 0.001 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.986975e-01 | 0.001 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.987139e-01 | 0.001 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.989434e-01 | 0.000 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.989690e-01 | 0.000 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.990992e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.991917e-01 | 0.000 | 0 | 0 |
| The canonical retinoid cycle in rods (twilight vision) | R-HSA-2453902 | 9.992130e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.992666e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.992676e-01 | 0.000 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.992704e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.992704e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.993520e-01 | 0.000 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.994639e-01 | 0.000 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.995995e-01 | 0.000 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.996501e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.996633e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.997263e-01 | 0.000 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.997263e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.997495e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.997582e-01 | 0.000 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.997695e-01 | 0.000 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.998113e-01 | 0.000 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.998220e-01 | 0.000 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.998333e-01 | 0.000 | 0 | 0 |
| Sialic acid metabolism | R-HSA-4085001 | 9.998813e-01 | 0.000 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.998963e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.998987e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.999194e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.999211e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999374e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999375e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.999396e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999458e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999526e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.999596e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.999598e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999732e-01 | 0.000 | 0 | 0 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 9.999844e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.999848e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999849e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999891e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.999893e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.999921e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999940e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.999944e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999976e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999981e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999986e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999993e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999994e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999995e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999995e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999996e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999997e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999998e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999998e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.999999e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
