MATK

Normalized values from positional scanning peptide array

Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities

Log-Odds: Probabilities / STY Background

Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities

T Sites Probabilities

Y Sites Probabilities

Log-Odds: S Sites / S Background

Log-Odds: T Sites / T Background

Log-Odds: Y Sites / Y Background

Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown

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substrate_uniprot site source substrate_genes site_seq
A0A2R8Y4L2 S95 Sugiyama HNRNPA1L3 HNRNPA1P48 RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED
A0MZ66 Y24 Sugiyama SHTN1 KIAA1598 sDEEKQLQLITsLKEQAIGEyEDLRAENQKTKEKCDKIRQE
A5A3E0 Y1062 Sugiyama POTEF A26C1B GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NHL2 Y319 Sugiyama TUBAL3 TTACFESSNQLVKCDPRLGKyMACCLLyRGDVVPKEVNAAI
B2RPK0 S15 Sugiyama HMGB1P1 HMG1L1 HMGB1L1 ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHSDAS
O00116 Y645 Sugiyama AGPS AAG5 QWLKESIsDVGFGMLKSVKEyVDPNNIFGNRNLL_______
O00165 S153 Sugiyama HAX1 HS1BP1 PDSHQPRIFGGVLESDARSEsPQPAPDWGsQRPFHRFDDVW
O00193 Y84 Sugiyama SMAP C11orf58 TSHFRTGEEDKKINEELEsQyQQsMDsKLSGRYRRHCGLGF
O00299 Y233 Sugiyama CLIC1 G6 NCC27 AyAREEFAstCPDDEEIELAyEQVAKALK____________
O00488 S93 Sugiyama ZNF593 ZT86 STNLKTHFRSKDHKKRLKQLsVEPysQEEAERAAGMGSYVP
O14602 Y35 Sugiyama EIF1AY GKNENESEKRELVFKEDGQEyAQVIKMLGNGRLEALCFDGV
O14910 Y133 Sugiyama LIN7A MALS1 VELI1 KTDEGLGFNVMGGKEQNsPIyIsRIIPGGVAERHGGLKRGD
O14950 Y156 Sugiyama MYL12B MRLC2 MYLC2B DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
O14979 Y167 Sugiyama HNRNPDL HNRPDL JKTBP DGKMFIGGLSWDTsKKDLtEyLSRFGEVVDCtIKTDPVTGR
O15013 Y1307 Sugiyama ARHGEF10 KIAA0294 sLsLsHGsssLEHRSEDsTIyDLLKDPVSLRSKARRAKKAK
O15047 S470 Sugiyama SETD1A KIAA0339 KMT2F SET1 SET1A sPEREEVRtsPRPAsPARsGsPAPEttNESVPFAQHSSLDS
O15067 Y538 Sugiyama PFAS KIAA0361 GAGGNGNVLKELsDPAGAIIytsRFQLGDPTLNALEIWGAE
O15371 Y50 Sugiyama EIF3D EIF3S7 yQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQYA
O43390 Y136 Sugiyama HNRNPR HNRPR QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O43390 Y376 Sugiyama HNRNPR HNRPR ILEKSFSEFGKLERVKKLKDyAFVHFEDRGAAVKAMDEMNG
O43615 Y201 Sugiyama TIMM44 MIMT44 TIM44 QGVEsVKKEIDDsVLGQtGPyRRPQRLRKRTEFAGDKFKEE
O43707 Y212 Sugiyama ACTN4 WKDGLAFNALIHRHRPELIEyDKLRKDDPVTNLNNAFEVAE
O43707 Y234 Sugiyama ACTN4 KLRKDDPVTNLNNAFEVAEKyLDIPKMLDAEDIVNtARPDE
O43852 Y106 Sugiyama CALU GFVtVDELKDWIKFAQKRWIyEDVERQWKGHDLNEDGLVsW
O43852 Y185 Sugiyama CALU KDGDLIATKEEFtAFLHPEEyDyMKDIVVQEtMEDIDKNAD
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O43852 Y47 Sugiyama CALU RVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQLtPE
O43865 Y28 Sugiyama AHCYL1 DCAL IRBIT XPVKONA PLPGVGEELKQAKEIEDAEKysFMATVTKAPKKQIQFADDM
O60343 T749 Sugiyama TBC1D4 AS160 KIAA0603 ENEIRQDTASESSDGEGRKRtSstCsNEsLsVGGTSVTPRR
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60506 Y133 Sugiyama SYNCRIP HNRPQ NSAP1 ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O60664 Y95 Sugiyama PLIN3 M6PRBP1 TIP47 VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE
O60716 S252 Sugiyama CTNND1 KIAA0384 sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL
O60841 S107 Sugiyama EIF5B IF2 KIAA0741 NEEEFtsKDKKKKGQKGKKQsFDDNDsEELEDKDsKSKKTA
O60841 S182 Sugiyama EIF5B IF2 KIAA0741 DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK
O60927 T75 Sugiyama PPP1R11 HCGV TCTE5 RRssKCCCIyEKPRAFGEsstEsDEEEEEGCGHtHCVRGHR
O75116 Y936 Sugiyama ROCK2 KIAA0619 EITLTKADSEQLARsIAEEQysDLEKEKIMKELEIKEMMAR
O75131 S240 Sugiyama CPNE3 CPN3 KIAA0636 DGSHDLIGTFQTTMTKLKEAsRssPVEFECINEKKRQKKKS
O75131 S242 Sugiyama CPNE3 CPN3 KIAA0636 SHDLIGTFQTTMTKLKEAsRssPVEFECINEKKRQKKKSYK
O75208 Y93 Sugiyama COQ9 C16orf49 HSPC326 PSEC0129 PEssHsPPRYTDQGGEEEEDyEsEEQLQHRILTAALEFVPA
O75347 Y75 Sugiyama TBCA EILQEsRMMIPDCQRRLEAAyLDLQRILENEKDLEEAEEyK
O75534 Y597 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR EKVNKtHsVNGItEEADPTIysGKVIRPLRSVDPTQTEYQG
O94826 S91 Sugiyama TOMM70 KIAA0719 TOM70 TOMM70A RGDASGLKRNSERKtPEGRAsPAPGsGHPEGPGAHLDMNsL
O94906 Y105 Sugiyama PRPF6 C20orf14 AGSLFSSGPYEKDDEEADAIyAALDKRMDERRKERREQREK
O95218 Y167 Sugiyama ZRANB2 ZIS ZNF265 EVEDKEsEGEEEDEDEDLsKyKLDEDEDEDDADLsKyNLDA
O95297 Y263 Sugiyama MPZL1 PZR UNQ849/PRO1787 QLDHsGGHHSDKINKSEsVVyADIRKN______________
O95757 Y629 Sugiyama HSPA4L APG1 HSPH3 OSP94 MQDKLEKERNDAKNAVEEyVyDFRDRLGtVYEKFITPEDLS
O96019 S233 Sugiyama ACTL6A BAF53 BAF53A INO80K MNIELVPPYMIASKEAVREGsPANWKRKEKLPQVTRSWHNY
P00338 Y10 Sugiyama LDHA PIG19 ___________MAtLKDQLIyNLLKEEQtPQNKITVVGVGA
P00338 Y239 Sugiyama LDHA PIG19 GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 T237 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD
P04406 Y314 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P04632 Y87 Sugiyama CAPNS1 CAPN4 CAPNS sAISEAAAQYNPEPPPPRtHysNIEANEsEEVRQFRRLFAQ
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05362 T454 Sugiyama ICAM1 DGtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTRKVTVNV
P05362 Y455 Sugiyama ICAM1 GtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTRKVTVNVL
P05455 Y104 Sugiyama SSB EDKTKIRRsPsKPLPEVTDEyKNDVKNRsVYIKGFPtDAtL
P05787 Y204 Sugiyama KRT8 CYK8 NKRTEMENEFVLIKKDVDEAyMNKVELESRLEGLTDEINFL
P06733 S268 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 ASEFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyP
P06733 Y189 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD
P06733 Y270 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV
P06733 Y280 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06748 S125 Sugiyama NPM1 NPM GsGPVHIsGQHLVAVEEDAEsEDEEEEDVKLLsIsGKRsAP
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 Y94 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK
P07237 Y99 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB LAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPKEytAG
P07355 Y188 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07355 Y199 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RAEDGsVIDyELIDQDARDLyDAGVKRKGTDVPKWIsIMTE
P07437 T107 Sugiyama TUBB TUBB5 OK/SW-cl.56 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKEAESC
P07437 Y50 Sugiyama TUBB TUBB5 OK/SW-cl.56 IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP
P07686 Y547 Sugiyama HEXB HCC7 DRLTRHRCRMVERGIAAQPLyAGyCNHENM___________
P07814 Y827 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 EIGQNIssNssAsILESKsLyDEVAAQGEVVRKLKAEKSPK
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900 Y160 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPM
P07900 Y284 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P07900 Y309 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF
P07900 Y313 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG
P07900 Y492 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR
P07900 Y493 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK
P07948 Y508 GPS6|SIGNOR|iPTMNet|EPSD|PSP LYN JTK8 PTFDYLQsVLDDFytAtEGQyQQQP________________
P08195 S607 Sugiyama SLC3A2 MDU1 ASLPAKADLLLstQPGREEGsPLELERLKLEPHEGLLLRFP
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 Y155 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB SAYLVAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPI
P08238 Y276 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238 Y301 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF
P08238 Y305 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08238 Y472 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB sELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEsKE
P08238 Y484 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR
P08238 Y485 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK
P08581 Y1365 Sugiyama MET IGEHyVHVNAtyVNVKCVAPyPSLLSSEDNADDEVDTRPAS
P09104 Y44 Sugiyama ENO2 LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK
P09429 S15 Sugiyama HMGB1 HMG1 ______MGKGDPKKPRGKMssyAFFVQtCREEHKKKHPDAs
P09651 S95 Sugiyama HNRNPA1 HNRPA1 RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
P09651 Y341 Sugiyama HNRNPA1 HNRPA1 QSSNFGPMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGss
P09651 Y347 Sugiyama HNRNPA1 HNRPA1 PMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGssssssyG
P0C7P4 Y100 Sugiyama UQCRFS1P1 UQCRFSL1 NVPASVCYSHTDIKVPDFSEyRRLEVLDSTKSSRESTEARK
P0CG38 Y1062 Sugiyama POTEI GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG39 Y1025 Sugiyama POTEJ GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11142 Y545 Sugiyama HSPA8 HSC70 HSP73 HSPA10 YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE
P11413 Y112 Sugiyama G6PD PEEKLKLEDFFARNsyVAGQyDDAAsyQRLNsHMNALHLGs
P11940 Y194 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF
P12277 Y125 Sugiyama CKB CKBB EHKTDLNPDNLQGGDDLDPNyVLssRVRTGRSIRGFCLPPH
P12277 Y39 Sugiyama CKB CKBB EFPDLSAHNNHMAKVLtPELyAELRAKSTPSGFTLDDVIQT
P12814 Y215 Sugiyama ACTN1 KLRKDDPLTNLNTAFDVAEKyLDIPKMLDAEDIVGtARPDE
P12814 Y842 Sugiyama ACTN1 DTDTADQVMASFKILAGDKNyITMDELRRELPPDQAEyCIA
P13489 S178 Sugiyama RNH1 PRI RNH SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP
P13639 S584 Sugiyama EEF2 EF2 DHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyM
P13639 Y443 Sugiyama EEF2 EF2 TGLKVRIMGPNytPGKKEDLyLKPIQRTILMMGRYVEPIED
P13639 Y671 Sugiyama EEF2 EF2 CFGPDGTGPNILTDITKGVQyLNEIKDSVVAGFQWATKEGA
P13667 Y448 Sugiyama PDIA4 ERP70 ERP72 RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs
P13667 Y458 Sugiyama PDIA4 ERP70 ERP72 VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI
P13667 Y565 Sugiyama PDIA4 ERP70 ERP72 DVLIEFYAPWCGHCKQLEPVyNsLAKKYKGQKGLVIAKMDA
P13674 Y282 Sugiyama P4HA1 P4HA ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP
P13861 S99 Sugiyama PRKAR2A PKR2 PRKAR2 EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI
P13929 Y44 Sugiyama ENO3 LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK
P14314 Y106 Sugiyama PRKCSH G19P1 yIPSNRVNDGVCDCCDGtDEyNsGVICENtCKEKGRKEREs
P14625 T171 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL
P14625 Y539 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDItsLDQyVERMKEKQDKIyFMAGsSRKEAEssPFVERLL
P15259 Y92 Sugiyama PGAM2 PGAMM DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV
P15311 S539 Sugiyama EZR VIL2 TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR
P15311 Y424 Sugiyama EZR VIL2 ERQAVDQIKsQEQLAAELAEytAKIALLEEARRRKEDEVEE
P17066 Y43 Sugiyama HSPA6 HSP70B' FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P17844 Y59 Sugiyama DDX5 G17P1 HELR HLR1 EKLVKKKWNLDELPKFEKNFyQEHPDLARRtAQEVETYRRS
P17980 Y381 Sugiyama PSMC3 TBP1 ARARIMQIHSRKMNVsPDVNyEELARCTDDFNGAQCKAVCV
P18124 Y155 Sugiyama RPL7 IVEPYIAWGYPNLKsVNELIyKRGYGKINKKRIALtDNALI
P18206 Y822 Sugiyama VCL KAVAGNIsDPGLQKsFLDsGyRILGAVAKVREAFQPQEPDF
P18615 S115 Sugiyama NELFE RD RDBP KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs
P18615 Y133 Sugiyama NELFE RD RDBP sIsADDDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEA
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18669 S134 Sugiyama PGAM1 PGAMA CDABP0006 IWRRsyDVPPPPMEPDHPFysNIsKDRRyADLtEDQLPsCE
P18669 S14 Sugiyama PGAM1 PGAMA CDABP0006 _______MAAYKLVLIRHGEsAWNLENRFsGWyDADLsPAG
P18669 Y142 Sugiyama PGAM1 PGAMA CDABP0006 PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR
P18669 Y92 Sugiyama PGAM1 PGAMA CDABP0006 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
P18754 Y89 Sugiyama RCC1 CHC1 VVQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsVEGSE
P18858 T183 Sugiyama LIG1 sLTEAEVAtEKEGEDGDQPttPPKPLKTSKAEtPtEsVsEP
P19105 Y155 Sugiyama MYL12A MLCB MRLC3 RLC DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
P20618 Y150 Sugiyama PSMB1 PSC5 FPYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSAS
P22234 Y22 Sugiyama PAICS ADE2 AIRC PAIS AtAEVLNIGKKLYEGKtKEVyELLDsPGKVLLQsKDQItAG
P22314 S56 Sugiyama UBA1 A1S9T UBE1 VPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSVL
P22314 Y55 Sugiyama UBA1 A1S9T UBE1 SVPTNGMAKNGsEADIDEGLysRQLyVLGHEAMKRLQTSSV
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P22626 Y336 Sugiyama HNRNPA2B1 HNRPA2B1 MKsGNFGGsRNMGGPyGGGNyGPGGsGGsGGyGGRsRy___
P23246 Y488 Sugiyama SFPQ PSF PMYQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQV
P23246 Y490 Sugiyama SFPQ PSF YQKEREtPPRFAQHGtFEyEysQRWKsLDEMEKQQREQVEK
P23434 Y139 Sugiyama GCSH EVTEINEALAENPGLVNKSCyEDGWLIKMtLsNPsELDELM
P23526 Y193 Sugiyama AHCY SAHH LKVPAINVNDsVtKsKFDNLyGCRESLIDGIKRATDVMIAG
P23528 T70 Sugiyama CFL1 CFL EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P23588 S207 Sugiyama EIF4B DRNRDsDKtDTDWRARPAtDsFDDyPPRRGDDsFGDKYRDR
P24752 Y214 Sugiyama ACAT1 ACAT MAT GsCAENTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNE
P24941 T160 Sugiyama CDK2 CDKN2 AIKLADFGLARAFGVPVRtytHEVVtLWyRAPEILLGCKYY
P25205 Y32 Sugiyama MCM3 LREAQRDyLDFLDDEEDQGIyQsKVRELIsDNQyRLIVNVN
P25205 Y456 Sugiyama MCM3 AGIHARLNARCsVLAAANPVyGRyDQyKTPMENIGLQDSLL
P26373 S77 Sugiyama RPL13 BBC1 OK/SW-cl.46 PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs
P26583 S15 Sugiyama HMGB2 HMG2 ______MGKGDPNKPRGKMssyAFFVQtCREEHKKKHPDss
P27348 Y149 Sugiyama YWHAQ LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG
P27540 Y561 Sugiyama ARNT BHLHE2 PLEKSDGLFAQDRDPRFsEIyHNINADQSKGISSSTVPATQ
P27695 Y128 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 LQELPGLSHQYWSAPsDKEGysGVGLLsRQCPLKVsyGIGD
P27695 Y45 Sugiyama APEX1 APE APE1 APEX APX HAP1 REF1 KSKTAAKKNDKEAAGEGPALyEDPPDQKtsPsGKPAtLKIC
P27816 Y47 Sugiyama MAP4 AtLEAEAFDDVVGETVGKTDyIPLLDVDEKtGNsESKKKPC
P27824 S362 Sugiyama CANX WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK
P29401 Y481 Sugiyama TKT AANTKGICFIRTsRPENAIIyNNNEDFQVGQAKVVLKSKDD
P29692 Y26 Sugiyama EEF1D EF1D LAHEKIWFDKFKYDDAERRFyEQMNGPVAGAsRQENGAsVI
P30043 Y205 Sugiyama BLVRB FLR SCAN MLRCLttDEyDGHstyPsHQyQ___________________
P30085 Y49 Sugiyama CMPK1 CMK CMPK UCK UMK UMPK ytHLSAGELLRDERKNPDsQyGELIEKYIKEGKIVPVEITI
P30086 S52 Sugiyama PEBP1 PBP PEBP AAVDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPD
P30086 T65 Sugiyama PEBP1 PBP PEBP QVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREWH
P30086 Y64 Sugiyama PEBP1 PBP PEBP tQVKNRPtsIsWDGLDsGKLytLVLtDPDAPsRKDPKYREW
P30101 Y115 Sugiyama PDIA3 ERP57 ERP60 GRP58 yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA
P30101 Y445 Sugiyama PDIA3 ERP57 ERP60 GRP58 KDPNIVIAKMDAtANDVPsPyEVRGFPtIyFsPANKKLNPK
P30101 Y479 Sugiyama PDIA3 ERP57 ERP60 GRP58 NKKLNPKKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKK
P30101 Y67 Sugiyama PDIA3 ERP57 ERP60 GRP58 LMLVEFFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTA
P31153 Y242 Sugiyama MAT2A AMS2 MATA2 LKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGPQGDAGLt
P31943 Y266 Sugiyama HNRNPH1 HNRPH HNRPH1 yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst
P31946 Y151 Sugiyama YWHAB LsEVAsGDNKQTtVsNsQQAyQEAFEIsKKEMQPTHPIRLG
P31946 Y21 Sugiyama YWHAB MTMDKsELVQKAKLAEQAERyDDMAAAMKAVtEQGHELsNE
P31948 Y354 Sugiyama STIP1 DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG
P31948 Y41 Sugiyama STIP1 DDALQCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDG
P32969 Y180 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________
P33176 Y516 Sugiyama KIF5B KNS KNS1 EELAVNyDQKSQEVEDKTKEyELLSDELNQKsATLAsIDAE
P33316 Y167 Sugiyama DUT PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P34932 Y30 Sugiyama HSPA4 APG2 HSPH2 FQSCYVAVARAGGIETIANEysDRCtPACIsFGPKNRSIGA
P34932 Y336 Sugiyama HSPA4 APG2 HSPH2 RVEPPLRSVLEQTKLKKEDIyAVEIVGGATRIPAVKEKISK
P34932 Y626 Sugiyama HSPA4 APG2 HSPH2 MQDKLEKERNDAKNAVEEyVyEMRDKLSGEYEKFVSEDDRN
P35221 S641 Sugiyama CTNNA1 GIRDIRKAVLMIRtPEELDDsDFEtEDFDVRsRtsVQtEDD
P35269 T389 Sugiyama GTF2F1 RAP74 PPKRERKPsGGSSRGNsRPGtPsAEGGstsstLRAAASKLE
P37802 T190 Sugiyama TAGLN2 KIAA0120 CDABP0035 GKNVIGLQMGtNRGAsQAGMtGyGMPRQIL___________
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38646 S89 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA
P38646 Y118 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 ERLVGMPAKRQAVtNPNNtFyAtKRLIGRRYDDPEVQKDIK
P39019 Y48 Sugiyama RPS19 LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39023 S265 Sugiyama RPL3 OK/SW-cl.32 HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY
P40429 Y149 Sugiyama RPL13A LKPTRKFAYLGRLAHEVGWKyQAVtAtLEEKRKEKAKIHYR
P40925 Y210 Sugiyama MDH1 MDHA tQYPDVNHAKVKLQGKEVGVyEALKDDsWLKGEFVttVQQR
P42166 S159 Sugiyama TMPO LAP2 RKLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsND
P42166 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDs
P42167 S159 Sugiyama TMPO LAP2 RKLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSND
P42167 T160 Sugiyama TMPO LAP2 KLYEKKLLKLREQGTESRsstPLPTISsSAENTRQNGSNDS
P42224 Y170 Sugiyama STAT1 KDKVMCIEHEIKsLEDLQDEyDFKCKTLQNREHETNGVAKS
P42679 S18 Sugiyama MATK CTK HYL ___MAGRGSLVSWRAFHGCDsAEELPRVsPRFLRAWHPPPV
P42679 S501 Sugiyama MATK CTK HYL ELRsAGAPASVsGQDADGstsPRsQEP______________
P42679 S504 Sugiyama MATK CTK HYL sAGAPASVsGQDADGstsPRsQEP_________________
P43243 S188 Sugiyama MATR3 KIAA0723 EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs
P43243 Y202 Sugiyama MATR3 KIAA0723 RHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyDRMDyEDD
P43487 S60 Sugiyama RANBP1 TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH
P43490 Y34 Sugiyama NAMPT PBEF PBEF1 ATDSYKVTHYKQYPPNTSKVysyFECREKKTENSKLRKVKY
P45974 Y849 Sugiyama USP5 ISOT WVIYNDQKVCASEKPPKDLGyIyFyQRVAS___________
P45974 Y851 Sugiyama USP5 ISOT IYNDQKVCASEKPPKDLGyIyFyQRVAS_____________
P45974 Y853 Sugiyama USP5 ISOT NDQKVCASEKPPKDLGyIyFyQRVAS_______________
P46063 Y61 Sugiyama RECQL RECQ1 RECQL1 VLTKKIKQCLEDsDAGAsNEyDssPAAWNKEDFPWSGKVKD
P46777 Y226 Sugiyama RPL5 MSTP030 DyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAHAA
P46777 Y253 Sugiyama RPL5 MSTP030 PDMMEEMyKKAHAAIRENPVyEKKPKKEVKKKRWNRPKMsL
P46778 T29 Sugiyama RPL21 RGTRYMFSRPFRKHGVVPLAtyMRIYKKGDIVDIKGMGTVQ
P46937 Y407 Sugiyama YAP1 YAP65 NsGtyHsRDEstDsGLsMssysVPRtPDDFLNsVDEMDTGD
P47756 Y59 Sugiyama CAPZB LLSSVDQPLKIARDKVVGKDyLLCDyNRDGDSyRsPWSNKy
P47813 Y35 Sugiyama EIF1AX EIF1A EIF4C GKNENESEKRELVFKEDGQEyAQVIKMLGNGRLEAMCFDGV
P47914 Y98 Sugiyama RPL29 PKEVKPKIPKGVSRKLDRLAyIAHPKLGKRARARIAKGLRL
P47985 Y91 Sugiyama UQCRFS1 NVPASVCYSHTDIKVPDFSEyRRLEVLDstKSSRESSEARK
P48741 Y43 Sugiyama HSPA7 HSP70B FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P49023 Y118 Sugiyama PXN sNPQDsVGsPCsRVGEEEHVysFPNKQKsAEPsPtVMstsL
P49023 Y88 Sugiyama PXN QWQPSSSRFIHQQPQsssPVyGssAKtssVsNPQDsVGsPC
P49207 Y32 Sugiyama RPL34 sYNtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGR
P49321 Y540 Sugiyama NASP DMLDLAKIIFKRQETKEAQLyAAQAHLKLGEVSVESENYVQ
P49327 Y45 Sugiyama FASN FAS NLIGGVDMVTDDDRRWKAGLyGLPRRsGKLKDLSRFDAsFF
P49840 Y279 Sugiyama GSK3A LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P49841 Y216 Sugiyama GSK3B LKLCDFGSAKQLVRGEPNVsyICsRYYRAPELIFGATDYTS
P50613 S164 Sugiyama CDK7 CAK CAK1 CDKN7 MO15 STK1 LLDENGVLKLADFGLAKsFGsPNRAytHQVVtRWYRAPELL
P50990 Y30 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 GFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTTRTAYGPN
P50991 Y269 Sugiyama CCT4 CCTD SRB IQFCLSAPKTDMDNQIVVSDyAQMDRVLREERAYILNLVKQ
P51965 Y77 Sugiyama UBE2E1 UBCH6 ADITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
P52565 Y156 Sugiyama ARHGDIA GDIA1 GVKIDKtDyMVGsYGPRAEEyEFLtPVEEAPKGMLARGsYs
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55060 Y369 Sugiyama CSE1L CAS XPO2 VPNMEFRAADEEAFEDNsEEyIRRDLEGsDIDTRRRAACDL
P55795 Y266 Sugiyama HNRNPH2 FTP3 HNRPH2 YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst
P60174 Y209 Sugiyama TPI1 TPI LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG
P60660 Y89 Sugiyama MYL6 HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI
P60709 T297 Sugiyama ACTB TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P60709 Y198 Sugiyama ACTB LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y306 Sugiyama ACTB DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P60709 Y362 Sugiyama ACTB GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P61247 Y256 Sugiyama RPS3A FTE1 MFTL sssGKAtGDEtGAKVERADGyEPPVQEsV____________
P61254 T8 Sugiyama RPL26 _____________MKFNPFVtsDRsKNRKRHFNAPsHIRRK
P61313 Y62 Sugiyama RPL15 EC45 TCBAP0781 PTRPDKARRLGYKAKQGyVIyRIRVRRGGRKRPVPKGAtyG
P61604 Y88 Sugiyama HSPE1 GDKVLLPEyGGtKVVLDDKDyFLFRDGDILGKyVD______
P61978 S75 Sugiyama HNRNPK HNRPK GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE
P61978 Y323 Sugiyama HNRNPK HNRPK RARNLPLPPPPPPRGGDLMAyDRRGRPGDRYDGMVGFSADE
P61981 Y20 Sugiyama YWHAG _MVDREQLVQKARLAEQAERyDDMAAAMKNVtELNEPLsNE
P62081 Y177 Sugiyama RPS7 HLDKAQQNNVEHKVEtFsGVyKKLTGKDVNFEFPEFQL___
P62191 Y184 Sugiyama PSMC1 MDDTDPLVTVMKVEKAPQETyADIGGLDNQIQEIKESVELP
P62258 Y152 Sugiyama YWHAE LAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLG
P62263 T133 Sugiyama RPS14 PRO2640 QsALRALARSGMKIGRIEDVtPIPsDstRRKGGRRGRRL__
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62280 Y55 Sugiyama RPS11 RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62750 Y144 Sugiyama RPL23A VNtLIRPDGEKKAYVRLAPDyDALDVANKIGII________
P62750 Y74 Sugiyama RPL23A LRRQPKYPRKSAPRRNKLDHyAIIKFPLTTEsAMKKIEDNN
P62753 Y156 Sugiyama RPS6 OK/SW-cl.2 KRASRIRKLFNLsKEDDVRQyVVRKPLNKEGKKPRTKAPKI
P62826 Y146 Sugiyama RAN ARA24 OK/SW-cl.81 IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR
P62906 T9 Sugiyama RPL10A NEDD6 ____________MSSKVsRDtLyEAVREVLHGNQRKRRKFL
P62906 Y11 Sugiyama RPL10A NEDD6 __________MSSKVsRDtLyEAVREVLHGNQRKRRKFLET
P62913 Y170 Sugiyama RPL11 CIGAKHRISKEEAMRWFQQKyDGIILPGK____________
P62917 S130 Sugiyama RPL8 GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62979 Y148 Sugiyama RPS27A UBA80 UBCEP1 AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________
P63173 T14 Sugiyama RPL38 _______MPRKIEEIKDFLLtARRKDAKSVKIKKNKDNVKF
P63220 Y53 Sugiyama RPS21 QMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRLA
P63261 T297 Sugiyama ACTG1 ACTG TTFNSIMKCDVDIRKDLyANtVLsGGttMyPGIADRMQKEI
P63261 Y198 Sugiyama ACTG1 ACTG LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y306 Sugiyama ACTG1 ACTG DVDIRKDLyANtVLsGGttMyPGIADRMQKEItALAPstMK
P63261 Y362 Sugiyama ACTG1 ACTG GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67809 S209 Sugiyama YBX1 NSEP1 YB1 RRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGEQ
P67809 Y208 Sugiyama YBX1 NSEP1 YB1 yRRRRFPPyyMRRPYGRRPQysNPPVQGEVMEGADNQGAGE
P67809 Y72 Sugiyama YBX1 NSEP1 YB1 KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
P67809 Y99 Sugiyama YBX1 NSEP1 YB1 DtKEDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKG
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 Y254 Sugiyama EEF1A1 EEF1A EF1A LENG7 CILPPtRPTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKP
P68104 Y29 Sugiyama EEF1A1 EEF1A EF1A LENG7 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 Y312 Sugiyama TUBA1B tNACFEPANQMVKCDPRHGKyMACCLLyRGDVVPKDVNAAI
P68363 Y432 Sugiyama TUBA1B GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
P68363 Y451 Sugiyama TUBA1B DyEEVGVDsVEGEGEEEGEEy____________________
P68366 Y312 Sugiyama TUBA4A TUBA1 tNACFEPANQMVKCDPRHGKyMACCLLyRGDVVPKDVNAAI
P78324 Y429 EPSD|PSP SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP RLHEPEKNAREITQDTNDItyADLNLPKGKKPAPQAAEPNN
P78324 Y453 EPSD|PSP SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP NLPKGKKPAPQAAEPNNHTEyASIQTSPQPASEDTLTyADL
P78345 S253 Sugiyama RPP38 DtsFEDLsKPKRKLADGRQAsVtLQPLKIKKLIPNPNKIRK
P85037 S445 Sugiyama FOXK1 MNF GLMsPRsGGLQtPECLsREGsPIPHDPEFGsKLASVPEYRY
P98082 Y38 Sugiyama DAB2 DOC2 AAPKAPsKKEKKKGPEKTDEyLLARFKGDGVKYKAKLIGID
Q00526 T160 Sugiyama CDK3 CDKN3 AIKLADFGLARAFGVPLRtYtHEVVTLWYRAPEILLGSKFY
Q00613 S363 Sugiyama HSF1 HSTF1 AsVTALtDARGHTDtEGRPPsPPPtstPEKCLsVACLDKNE
Q00839 Y257 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 QKGGDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVE
Q00839 Y260 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED
Q01105 Y146 Sugiyama SET tEFEDIKsGyRIDFyFDENPyFENKVLSKEFHLNEsGDPss
Q04446 Y657 Sugiyama GBE1 RVGTALPGKFKIVLDSDAAEyGGHQRLDHSTDFFSEAFEHN
Q04837 S67 Sugiyama SSBP1 SSBP QVEGKNPVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRI
Q04837 Y73 Sugiyama SSBP1 SSBP PVTIFSLATNEMWRsGDsEVyQLGDVsQKTTWHRISVFRPG
Q05639 Y254 Sugiyama EEF1A2 EEF1AL STN TILPPTRPTDKPLRLPLQDVyKIGGIGtVPVGRVETGILRP
Q05639 Y29 Sugiyama EEF1A2 EEF1AL STN NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q06210 S261 Sugiyama GFPT1 GFAT GFPT GsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDA
Q06830 Y116 Sugiyama PRDX1 PAGA PAGB TDPX2 GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK
Q07666 S20 Sugiyama KHDRBS1 SAM68 _MQRRDDPAARMsRssGRsGsMDPsGAHPsVRQtPsRQPPL
Q07666 Y145 Sugiyama KHDRBS1 SAM68 LtAEIEKIQKGDSKKDDEENyLDLFsHKNMKLKERVLIPVK
Q07955 Y189 Sugiyama SRSF1 ASF SF2 SF2P33 SFRS1 OK/SW-cl.3 TYAVRKLDNTKFRsHEGEtAyIRVKVDGPRsPsyGRsRsRs
Q08043 Y229 Sugiyama ACTN3 KLRKDDPIGNLNTAFEVAEKyLDIPKMLDAEDIVNtPKPDE
Q08830 Y80 Sugiyama FGL1 HFREP1 VQFLDKGDENTVIDLGSKRQyADCSEIFNDGyKLSGFYKIK
Q12996 Y708 Sugiyama CSTF3 NEDsDEDEEKGAVVPPVHDIyRARQQKRIR___________
Q13228 Y28 Sugiyama SELENBP1 SBP CGPGySTPLEAMKGPREEIVyLPCIyRNtGtEAPDyLATVD
Q13247 S303 Sugiyama SRSF6 SFRS6 SRP55 ENGKGDIKsKSRsRsQsRsNsPLPVPPsKARsVsPPPKRAT
Q13263 Y133 Sugiyama TRIM28 KAP1 RNF96 TIF1B TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC
Q13263 Y242 Sugiyama TRIM28 KAP1 RNF96 TIF1B ESCDTLTCRDCQLNAHKDHQyQFLEDAVRNQRKLLAsLVKR
Q13283 S231 Sugiyama G3BP1 G3BP QEEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsW
Q13283 S232 Sugiyama G3BP1 G3BP EEKPEPVLEETAPEDAQKsssPAPADIAQtVQEDLRtFsWA
Q13310 Y194 Sugiyama PABPC4 APP1 PABP4 KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF
Q13404 Y145 Sugiyama UBE2V1 CROC1 UBE2V UEV1 P/OKcl.19 RRLMMSKENMKLPQPPEGQCysN__________________
Q13405 Y45 Sugiyama MRPL49 C11orf4 NOF1 OK/SW-cl.67 LLSQTQGPPDYPRFVEsVDEyQFVERLLPATRIPDPPKHEH
Q13442 Y17 Sugiyama PDAP1 HASPP28 ____MPKGGRKGGHKGRARQytsPEEIDAQLQAEKQKAREE
Q13509 T107 Sugiyama TUBB3 TUBB4 PDNFIFGQSGAGNNWAKGHytEGAELVDsVLDVVRKECENC
Q13561 Y6 Sugiyama DCTN2 DCTN50 _______________MADPKyADLPGIARNEPDVYETSDLP
Q13561 Y86 Sugiyama DCTN2 DCTN50 GLDFsDRIGKTKRtGyEsGEyEMLGEGLGVKETPQQKYQRL
Q13601 Y287 Sugiyama KRR1 HRB2 tPFPPPQPESQIDKELAsGEyFLKANQKKRQKMEAIKAKQA
Q13765 S117 Sugiyama NACA HSD48 RKSKNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQL
Q13765 Y120 Sugiyama NACA HSD48 KNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAAA
Q13885 T107 Sugiyama TUBB2A TUBB2 PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q14126 Y968 Sugiyama DSG2 CDHF5 PTTVILGPSQPQSLIVTERVyAPAstLVDQPyANEGtVVVT
Q14152 S584 Sugiyama EIF3A EIF3S10 KIAA0139 EHQRILARRQtIEERKERLEsLNIQREKEELEQREAELQKV
Q14155 S518 Sugiyama ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314 ERYLLLFPNVLLMLSASPRMsGFIyQGKLPtTGMTITKLED
Q14247 S447 Sugiyama CTTN EMS1 FKAELsyRGPVsGtEPEPVysMEAADyREASSQQGLAYATE
Q14247 Y334 Sugiyama CTTN EMS1 KDRMDKNAstFEDVtQVssAyQKTVPVEAVtsKtsNIRANF
Q14247 Y421 Sugiyama CTTN EMS1 tPPVsPAPQPtEERLPssPVyEDAAsFKAELsyRGPVsGtE
Q14247 Y446 Sugiyama CTTN EMS1 sFKAELsyRGPVsGtEPEPVysMEAADyREASSQQGLAYAT
Q14444 Y99 Sugiyama CAPRIN1 GPIAP1 GPIP137 M11S1 RNG105 QERMNKGERLNQDQLDAVsKyQEVtNNLEFAKELQRsFMAL
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14568 Y160 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERM
Q14568 Y283 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q14693 S434 Sugiyama LPIN1 KIAA0188 FPKNGDPSGLAKHASDNGARsANQsPQSVGSSGVDSGVEST
Q14693 S438 Sugiyama LPIN1 KIAA0188 GDPSGLAKHASDNGARsANQsPQSVGSSGVDSGVESTSDGL
Q14974 Y529 Sugiyama KPNB1 NTF97 KLLETTDRPDGHQNNLRSSAyEsLMEIVKNSAKDCYPAVQK
Q14CX7 Y19 Sugiyama NAA25 C12orf30 MDM20 NAP1 __MATRGHVQDPNDRRLRPIyDyLDNGNNKMAIQQADKLLK
Q14CX7 Y21 Sugiyama NAA25 C12orf30 MDM20 NAP1 MATRGHVQDPNDRRLRPIyDyLDNGNNKMAIQQADKLLKKH
Q15024 Y13 Sugiyama EXOSC7 KIAA0116 RRP42 ________MASVTLSEAEKVyIVHGVQEDLRVDGRGCEDYR
Q15052 S488 Sugiyama ARHGEF6 COOL2 KIAA0006 PIXA ERYLMLFSNVLIMLSASPRMsGFIYQGKIPIAGTVVTRLDE
Q15293 Y278 Sugiyama RCN1 RCN LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE
Q15369 Y8 Sugiyama ELOC TCEB1 _____________MDGEEKtyGGCEGPDAMyVKLISSDGHE
Q15427 Y16 Sugiyama SF3B4 SAP49 _____MAAGPISERNQDAtVyVGGLDEKVSEPLLWELFLQA
Q15459 S451 Sugiyama SF3A1 SAP114 IGLLDPRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAE
Q15459 Y456 Sugiyama SF3A1 SAP114 PRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAERRtDI
Q15527 Y123 Sugiyama SURF2 GRRYQRALCKYEECQKQGVEyVPACLVHRRRRREDQMDGDG
Q15785 Y25 Sugiyama TOMM34 URCC3 FPDsVEELRAAGNESFRNGQyAEASALyGRALRVLQAQGss
Q15785 Y54 Sugiyama TOMM34 URCC3 RALRVLQAQGssDPEEEsVLysNRAACHLKDGNCRDCIKDC
Q16513 T958 Sugiyama PKN2 PRK2 PRKCL2 RGREDVSNFDDEFtsEAPILtPPREPRILsEEEQEMFRDFD
Q1KMD3 Y215 Sugiyama HNRNPUL2 HNRPUL2 GERRGVKRQRDEKDEHGRAyyEFREEAYHsRsKsPLPPEEE
Q27J81 T1206 Sugiyama INF2 C14orf151 C14orf173 DtsLDKsFsEDAVtDssGsGtLPRARGRASKGTGKRRKKRP
Q32MZ4 Y597 Sugiyama LRRFIP1 GCF2 TRIP KKKKsPVPVETLKDVKKELtyQNTDLsEIKEEEQVKstDRK
Q32P51 S95 Sugiyama HNRNPA1L2 HNRNPA1L TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF8 Y198 Sugiyama HSP90AB2P HSP90BB DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q58FF8 Y260 Sugiyama HSP90AB2P HSP90BB VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW
Q58FF8 Y261 Sugiyama HSP90AB2P HSP90BB RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK
Q58FG0 Y177 Sugiyama HSP90AA5P HSP90AE GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ
Q58FG0 Y178 Sugiyama HSP90AA5P HSP90AE QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK
Q5T035 T62 Sugiyama FAM120A2P C9orf129 yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER
Q5T035 Y67 Sugiyama FAM120A2P C9orf129 SEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERSLPIN
Q5VTE0 Y254 Sugiyama EEF1A1P5 EEF1AL3 CILPPtRPTDKPLRLPLQDVyKIGGIGtVPVGRVEtGVLKP
Q5VTE0 Y29 Sugiyama EEF1A1P5 EEF1AL3 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q5VV41 Y216 Sugiyama ARHGEF16 EPHEXIN4 NBR KKTLGRKRGHKGsFKDDPQLyQEIQERGLNtsQEsDDDILD
Q63ZY3 S356 Sugiyama KANK2 ANKRD25 KIAA1518 MXRA3 SIP PREVEVVASTAAGAPAQRAQsLEPYGtGLRALAMPGRPEsP
Q6PCE3 S175 Sugiyama PGM2L1 BM32A PFVPYAVQKLKAVAGVMItAsHNRKEDNGYKVYWETGAQIT
Q6PKG0 Y777 Sugiyama LARP1 KIAA0731 LARP APEPstIARsLPttVPEsPNyRNtRtPRtPRtPQLKDSSQT
Q6S8J3 Y1062 Sugiyama POTEE A26C1A POTE2 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6UN15 S492 Sugiyama FIP1L1 FIP1 RHE DRDRDRERERTRERERERDHsPtPsVFNsDEERyRYREYAE
Q6UN15 T494 Sugiyama FIP1L1 FIP1 RHE DRDRERERTRERERERDHsPtPsVFNsDEERyRYREYAERG
Q71U36 Y312 Sugiyama TUBA1A TUBA3 tNACFEPANQMVKCDPRHGKyMACCLLyRGDVVPKDVNAAI
Q71U36 Y432 Sugiyama TUBA1A TUBA3 GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_
Q71U36 Y451 Sugiyama TUBA1A TUBA3 DyEEVGVDsVEGEGEEEGEEy____________________
Q7L2J0 S216 Sugiyama MEPCE BCDIN3 NLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDIt
Q7L2J0 S217 Sugiyama MEPCE BCDIN3 LNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPKDItD
Q7L2J0 T213 Sugiyama MEPCE BCDIN3 DPLNLNSLLDEEVSRtLNAEtPKssPLPAKGRDPVEILIPK
Q7Z4S6 S1212 Sugiyama KIF21A KIAA1708 KIF2 GQEIGMNTETSGTSAREKELsPPPGLPSKIGsIsRQssLsE
Q86V81 S239 Sugiyama ALYREF ALY BEF THOC4 tRGGARGRGRGAGRNSKQQLsAEELDAQLDAyNARMDts__
Q86W56 Y832 Sugiyama PARG DDWQRRCTEIVAIDALHFRRyLDQFVPEKMRRELNKAYCGF
Q8IWW6 Y243 Sugiyama ARHGAP12 sTEQIRAttPPNQGRPDsPVyANLQELKISQSALPPLPGSP
Q8IZ21 S118 Sugiyama PHACTR4 PRO2963 PSDAMLKNGHTTPIGNARsssPVQVEEEPVRLAsLRKAIPE
Q8N0Y7 S134 Sugiyama PGAM4 PGAM3 IWRRsyDVPPPPMEPDHPFysNIsKDRRYADLTEDQLPSYE
Q8N0Y7 Y92 Sugiyama PGAM4 PGAM3 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
Q8N5P1 Y97 Sugiyama ZC3H8 ZC3HDC8 sDNDICsQEsEDNFAKELQQyIQAREMANAAQPEESTKKEG
Q8N684 S205 Sugiyama CPSF7 IPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLPYF
Q8N684 T203 Sugiyama CPSF7 GGIPPRAHsRDssDsADGRAtPsENLVPSSARVDKPPSVLP
Q8N7H5 Y136 Sugiyama PAF1 PD2 tssKRSQQHAKVVPWMRKTEyISTEFNRYGIsNEKPEVKIG
Q8N7H5 Y169 Sugiyama PAF1 PD2 EKPEVKIGVSVKQQFTEEEIyKDRDSQITAIEKTFEDAQKS
Q8NDI1 Y585 Sugiyama EHBP1 KIAA0903 NACSIN TYKVGNYETDTNssVDQEKFyAELSDLKREPELQQPISGAV
Q8TC07 S675 Sugiyama TBC1D15 TSAFQSNALPTLSASGARNDsPtQIPVssDVCRLtPA____
Q8TD19 Y52 Sugiyama NEK9 KIAA1995 NEK8 NERCC PSASQGPRAGGGAAEQEELHyIPIRVLGRGAFGEAtLyRRT
Q8WYP5 Y1790 Sugiyama AHCTF1 ELYS TMBS62 MSTP108 QSVRKKTRKAKEISEASENIySDVRGLsQNQQIPQNsVtPR
Q969T4 Y91 Sugiyama UBE2E3 UBCE4 UBCH9 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96D46 Y459 Sugiyama NMD3 CGI-07 YQDFLEDLEEDEAIRKNVNIyRDsAIPVEsDtDDEGAPRIS
Q96EU6 Y138 Sugiyama RRP36 C6orf153 HSPC253 RDPRFDDLSGEYNPEVFDKtyQFLNDIRAKEKELVKKQLKK
Q96G46 T273 Sugiyama DUS3L GAPRQENCGAQQVPAGPGtstPPssPVRtCGPLtDEDVVRL
Q96LR5 Y85 Sugiyama UBE2E2 UBCH8 AEITLDPPPNCSAGPKGDNIyEWRSTILGPPGSVYEGGVFF
Q96MU7 S308 Sugiyama YTHDC1 KIAA1966 YT521 GSGTDGsDEKKKERKRARGIsPIVFDRsGssAsESYAGsEK
Q96P70 Y889 Sugiyama IPO9 IMP9 KIAA1192 RANBP9 HSPC273 HGINADDKRLQDIRVKGEEIysMDEGIRTRSKSAKNPERWT
Q96S44 T8 Sugiyama TP53RK C20orf64 PRPK _____________MAAARAttPADGEEPAPEAEALAAARER
Q99613 Y881 Sugiyama EIF3C EIF3S8 EKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMRR
Q99733 Y95 Sugiyama NAP1L4 NAP2 VRCAHIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVE
Q99733 Y99 Sugiyama NAP1L4 NAP2 HIEAKFyEEVHDLERKyAALyQPLFDKRREFItGDVEPtDA
Q99848 Y265 Sugiyama EBNA1BP2 EBP2 NQKFGFGGKKKGSKWNtREsyDDVssFRAKTAHGRGLKRPG
Q99961 Y57 Sugiyama SH3GL1 CNSA1 SH3D2B EKKVDVTSKAVTEVLARTIEyLQPNPAsRAKLTMLNTVSKI
Q99962 Y57 Sugiyama SH3GL2 CNSA2 SH3D2A ERKVDVTSRAVMEIMTKTIEyLQPNPAsRAKLSMINTMsKI
Q9BPX3 Y929 Sugiyama NCAPG CAPG NYMEL3 QDATLTTTTFQNEDEKNKEVyMtPLRGVKATQASKSTQLKT
Q9BQE3 Y312 Sugiyama TUBA1C TUBA6 TNACFEPANQMVKCDPRHGKyMACCLLyRGDVVPKDVNAAI
Q9BQE3 Y432 Sugiyama TUBA1C TUBA6 GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___
Q9BRK5 Y342 Sugiyama SDF4 CAB45 PSEC0034 MIAVADENQNHHLEPEEVLKysEFFTGSKLVDYARsVHEEF
Q9BVA1 T107 Sugiyama TUBB2B PDNFVFGQsGAGNNWAKGHytEGAELVDsVLDVVRKESESC
Q9BVP2 Y548 Sugiyama GNL3 E2IG3 NS RSFILDKIIEEDDAyDFSTDyV___________________
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BYX7 Y362 Sugiyama POTEKP ACTBL3 FKSG30 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q9C0C2 S1103 Sugiyama TNKS1BP1 KIAA1741 TAB182 KRGWVGEFSLSVGPQREAAFsPGQQDWsRDFCIEASERsyQ
Q9C0C2 S672 Sugiyama TNKS1BP1 KIAA1741 TAB182 TLARAETtQARtEAQDLCRAsPEPPGPEsSSRWLDDLLAsP
Q9C0C9 S87 Sugiyama UBE2O KIAA1734 SGRYRGsVHFGLVRLIHGEDsDsEGEEEGRGssGCSEAGGA
Q9C0C9 S89 Sugiyama UBE2O KIAA1734 RYRGsVHFGLVRLIHGEDsDsEGEEEGRGssGCSEAGGAGH
Q9H1E3 S144 Sugiyama NUCKS1 NUCKS JC7 PFQEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPER
Q9H1E3 Y146 Sugiyama NUCKS1 NUCKS JC7 QEKDsGsDEDFLMEDDDDsDyGSsKKKNKKMVKKSKPERKE
Q9H2U1 Y169 Sugiyama DHX36 DDX36 KIAA1488 MLEL1 RHAU NQEKKMFRIRNRsyIDRDsEyLLQENEPDGtLDQKLLEDLQ
Q9H4A3 S1261 Sugiyama WNK1 HSN2 KDP KIAA0344 PRKWNK1 GIPTSSLTQVVHSAGRRFIVsPVPEsRLRESKVFPSEITDT
Q9H6F5 S91 Sugiyama CCDC86 CYCLON RLQQGAGLEsPQGQPEPGAAsPQRQQDLHLEsPQRQPEysP
Q9H6F5 Y109 Sugiyama CCDC86 CYCLON AAsPQRQQDLHLEsPQRQPEysPEsPRCQPKPSEEAPKCsQ
Q9H6Z4 T363 Sugiyama RANBP3 DANRENAAAEsGsEsssQEAtPEKESLAEsAAAyTKATARK
Q9H7D7 S121 Sugiyama WDR26 CDW2 MIP2 PRO0852 ASSSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLN
Q9H7N4 S498 Sugiyama SCAF1 SFRS19 SRA1 GGLDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKK
Q9H7N4 S500 Sugiyama SCAF1 SFRS19 SRA1 LDLRRKILTQRRERyRQRsPsPAPAPAPAAAAGPPTRKKSR
Q9H814 Y57 Sugiyama PHAX RNUXA GDsAMRAFQNTAtACAPVSHyRAVESVDSSEESFSDSDDDS
Q9HAP6 Y118 Sugiyama LIN7B MALS2 VELI2 UNQ3116/PRO10200 KTDEGLGFNIMGGKEQNsPIyIsRVIPGGVADRHGGLKRGD
Q9HB07 Y189 Sugiyama MYG1 C12orf10 VEEVDAVDNGISQWAEGEPRyALttTLsARVARLNPTWNHP
Q9NPI6 S525 Sugiyama DCP1A SMIF SVFQQTVTRSSDLERKAssPsPLtIGtPEsQRKPSIILSKs
Q9NPQ8 T441 Sugiyama RIC8A AARGLMAGGRPEGQysEDEDtDtDEyKEAKAsINPVTGRVE
Q9NUP9 Y118 Sugiyama LIN7C MALS3 VELI3 KTEEGLGFNIMGGKEQNsPIyIsRIIPGGIADRHGGLKRGD
Q9NWB6 S77 Sugiyama ARGLU1 RsRstNTAVSRRERDRERAssPPDRIDIFGRTVSKRSSLDE
Q9NZB2 T413 Sugiyama FAM120A C9orf10 KIAA0183 OSSA yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER
Q9NZB2 Y418 Sugiyama FAM120A C9orf10 KIAA0183 OSSA SEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERssPIN
Q9UBR2 Y76 Sugiyama CTSZ YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA
Q9UGV2 S333 Sugiyama NDRG3 MGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQsD
Q9UI15 T190 Sugiyama TAGLN3 NP25 GQNVIGLQMGSNKGAsQAGMtGyGMPRQIM___________
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9UII2 Y58 Sugiyama ATP5IF1 ATPI ATPIF1 GsIREAGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEI
Q9UK59 Y533 Sugiyama DBR1 LsDEHEPEQRKKIKRRNQAIyAAVDDDDDDAA_________
Q9UKK9 Y16 Sugiyama NUDT5 NUDIX5 HSPC115 _____MEsQEPtEssQNGKQyIISEELIsEGKWVKLEKTTY
Q9UMX5 Y65 Sugiyama NENF CIR2 SPUF RLFtEEELARYGGEEEDQPIyLAVKGVVFDVtSGKEFYGRG
Q9UNX3 T8 Sugiyama RPL26L1 RPL26P1 _____________MKFNPFVtsDRsKNRKRHFNAPSHVRRK
Q9UQ35 S1103 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 sPsLQSKSQTsPKGGRsRsssPVtELAsRsPIRQDRGEFsA
Q9UQ35 S1648 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 APRALPRRSRSGSSSKGRGPsPEGssstEssPEHPPKSRTA
Q9UQ35 S2132 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 SRMsCFsRPsMsPtPLDRCRsPGMLEPLGssRtPMsVLQQA
Q9UQ35 S2398 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 ANLtsPRVPLsAyERVsGRtsPPLLDRARsRtPPsAPsQsR
Q9UQ35 S876 Sugiyama SRRM2 KIAA0324 SRL300 SRM300 HSPC075 tsPQANEQsVtPQRRsCFEssPDPELKsRtPsRHsCsGssP
Q9Y266 T145 Sugiyama NUDC AENHEAQLKNGsLDsPGKQDtEEDEEEDEKDKGKLKPNLGN
Q9Y2T7 Y107 Sugiyama YBX2 CSDA3 MSY2 KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
Q9Y2U5 S164 Sugiyama MAP3K2 MAPKKK2 MEKK2 FGAERKKRLsIIGPTSRDRssPPPGYIPDELHQVARNGSFT
Q9Y3D8 Y31 Sugiyama AK6 CINAP AD-004 CGI-137 TPGVGKTTLGKELASKSGLKyINVGDLAREEQLYDGYDEEY
Q9Y3U8 Y53 Sugiyama RPL36 LTKHTKFVRDMIREVCGFAPyERRAMELLKVSKDKRALKFI
Q9Y490 Y1893 Sugiyama TLN1 KIAA1027 TLN TKsNtsPEELGPLANQLTsDyGRLAsEAKPAAVAAENEEIG
Q9Y5S9 S56 Sugiyama RBM8A RBM8 HSPC114 MDS014 KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF
Q9Y639 S213 Sugiyama NPTN SDFR1 SDR1 ATRKNASNMEYRINKPRAEDsGEyHCVyHFVsAPKANATIE
Q9Y639 Y216 Sugiyama NPTN SDFR1 SDR1 KNASNMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKA
Q9Y639 Y220 Sugiyama NPTN SDFR1 SDR1 NMEYRINKPRAEDsGEyHCVyHFVsAPKANATIEVKAAPDI
Q9Y696 Y244 Sugiyama CLIC4 AysRDEFtNtCPsDKEVEIAysDVAKRLTK___________
Site Promiscuity

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
Packaging Of Telomere Ends R-HSA-171306 1.225686e-13 12.912 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 1.225686e-13 12.912 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 4.407585e-14 13.356 0 0
DNA methylation R-HSA-5334118 2.299272e-13 12.638 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 2.604583e-13 12.584 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 5.527800e-13 12.257 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 7.290835e-13 12.137 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 1.241118e-12 11.906 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.076583e-12 11.968 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 1.241118e-12 11.906 0 0
PRC2 methylates histones and DNA R-HSA-212300 2.058131e-12 11.687 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 2.793432e-12 11.554 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 2.626455e-12 11.581 0 0
Cleavage of the damaged purine R-HSA-110331 2.626455e-12 11.581 0 0
Depurination R-HSA-73927 3.332667e-12 11.477 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 5.280443e-12 11.277 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 5.280443e-12 11.277 0 0
HDACs deacetylate histones R-HSA-3214815 5.941359e-12 11.226 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 6.596612e-12 11.181 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 1.015033e-11 10.994 0 0
Depyrimidination R-HSA-73928 1.015033e-11 10.994 0 0
Defective pyroptosis R-HSA-9710421 1.250700e-11 10.903 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 1.419831e-11 10.848 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 1.875244e-11 10.727 0 0
Nucleosome assembly R-HSA-774815 1.875244e-11 10.727 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 1.974421e-11 10.705 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 2.282574e-11 10.642 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 2.983902e-11 10.525 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 3.344280e-11 10.476 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 5.016776e-11 10.300 0 0
ESR-mediated signaling R-HSA-8939211 4.995104e-11 10.301 0 0
Meiotic recombination R-HSA-912446 5.778567e-11 10.238 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 6.889433e-11 10.162 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 6.728673e-11 10.172 0 0
Meiotic synapsis R-HSA-1221632 8.188772e-11 10.087 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 8.188772e-11 10.087 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 9.704448e-11 10.013 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 1.861791e-10 9.730 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 2.176918e-10 9.662 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 2.539152e-10 9.595 0 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.430144e-10 9.465 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 4.887102e-10 9.311 0 0
Activation of HOX genes during differentiation R-HSA-5619507 4.887102e-10 9.311 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 6.096351e-10 9.215 0 0
Cell-Cell communication R-HSA-1500931 6.364584e-10 9.196 0 0
DNA Double Strand Break Response R-HSA-5693606 7.002722e-10 9.155 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 1.049179e-09 8.979 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 1.087063e-09 8.964 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 1.196132e-09 8.922 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 1.196132e-09 8.922 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 1.361266e-09 8.866 0 0
Assembly of the pre-replicative complex R-HSA-68867 1.508347e-09 8.821 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.754083e-09 8.756 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 2.245508e-09 8.649 0 0
RNA Polymerase I Transcription R-HSA-73864 2.856738e-09 8.544 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 3.612784e-09 8.442 0 0
Processing of DNA double-strand break ends R-HSA-5693607 4.054108e-09 8.392 0 0
Amyloid fiber formation R-HSA-977225 4.054108e-09 8.392 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 4.543030e-09 8.343 0 0
Meiosis R-HSA-1500620 6.341747e-09 8.198 0 0
DNA Replication Pre-Initiation R-HSA-69002 8.852804e-09 8.053 0 0
Diseases of programmed cell death R-HSA-9645723 9.720255e-09 8.012 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 1.261376e-08 7.899 0 0
Base Excision Repair R-HSA-73884 1.194874e-08 7.923 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.681424e-08 7.774 1 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 2.298840e-08 7.638 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 2.298840e-08 7.638 0 0
Cell junction organization R-HSA-446728 2.428596e-08 7.615 0 0
Signaling by Nuclear Receptors R-HSA-9006931 3.147167e-08 7.502 0 0
Telomere Maintenance R-HSA-157579 2.868523e-08 7.542 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 3.151811e-08 7.501 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 3.399207e-08 7.469 0 0
HATs acetylate histones R-HSA-3214847 3.447183e-08 7.463 0 0
Cell-cell junction organization R-HSA-421270 4.021719e-08 7.396 0 0
Regulation of endogenous retroelements R-HSA-9842860 4.510555e-08 7.346 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 4.510555e-08 7.346 0 0
G2/M Checkpoints R-HSA-69481 4.994914e-08 7.301 0 0
Signal Transduction R-HSA-162582 6.344398e-08 7.198 1 0
Gene Silencing by RNA R-HSA-211000 7.547965e-08 7.122 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 9.096683e-08 7.041 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 1.328658e-07 6.877 0 0
Ub-specific processing proteases R-HSA-5689880 1.717478e-07 6.765 0 0
Homology Directed Repair R-HSA-5693538 2.099433e-07 6.678 0 0
Mitotic Prophase R-HSA-68875 2.432724e-07 6.614 0 0
Chromosome Maintenance R-HSA-73886 2.616298e-07 6.582 0 0
Adherens junctions interactions R-HSA-418990 3.063819e-07 6.514 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 3.182868e-07 6.497 0 0
DNA Replication R-HSA-69306 3.572669e-07 6.447 0 0
Developmental Biology R-HSA-1266738 3.583141e-07 6.446 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 3.730816e-07 6.428 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 3.730816e-07 6.428 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 3.730816e-07 6.428 0 0
Reproduction R-HSA-1474165 5.607058e-07 6.251 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 1.124136e-06 5.949 0 0
Immune System R-HSA-168256 1.479397e-06 5.830 0 0
Deubiquitination R-HSA-5688426 1.656321e-06 5.781 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.726935e-06 5.763 0 0
TCF dependent signaling in response to WNT R-HSA-201681 1.992514e-06 5.701 0 0
DNA Double-Strand Break Repair R-HSA-5693532 2.545380e-06 5.594 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 2.689597e-06 5.570 0 0
HCMV Late Events R-HSA-9610379 3.166138e-06 5.499 0 0
Protein ubiquitination R-HSA-8852135 3.477854e-06 5.459 0 0
Chromatin modifying enzymes R-HSA-3247509 3.722299e-06 5.429 0 0
HCMV Early Events R-HSA-9609690 3.744213e-06 5.427 0 0
Co-inhibition by PD-1 R-HSA-389948 4.505174e-06 5.346 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 4.686037e-06 5.329 0 0
Signaling by NOTCH R-HSA-157118 4.775484e-06 5.321 0 0
Chromatin organization R-HSA-4839726 6.850649e-06 5.164 0 0
Adaptive Immune System R-HSA-1280218 7.837143e-06 5.106 0 0
Cellular Senescence R-HSA-2559583 1.048149e-05 4.980 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 1.174117e-05 4.930 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.753452e-05 4.756 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.799674e-05 4.745 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 2.792272e-05 4.554 0 0
Viral Infection Pathways R-HSA-9824446 2.944145e-05 4.531 0 0
HCMV Infection R-HSA-9609646 3.503077e-05 4.456 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 3.630807e-05 4.440 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 3.971805e-05 4.401 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 4.015582e-05 4.396 0 0
Infectious disease R-HSA-5663205 4.408167e-05 4.356 0 0
Cell Cycle Checkpoints R-HSA-69620 4.626157e-05 4.335 0 0
RUNX1 regulates transcription of genes involved in BCR signaling R-HSA-8939245 6.258361e-05 4.204 0 0
Disease R-HSA-1643685 6.351649e-05 4.197 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 7.870801e-05 4.104 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 9.211850e-05 4.036 0 0
Cellular responses to stimuli R-HSA-8953897 9.957149e-05 4.002 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.243244e-04 3.905 0 0
Erythropoietin activates STAT5 R-HSA-9027283 1.309675e-04 3.883 0 0
Signaling by VEGF R-HSA-194138 1.374058e-04 3.862 0 0
MAPK family signaling cascades R-HSA-5683057 1.600432e-04 3.796 0 0
Signaling by WNT R-HSA-195721 1.617654e-04 3.791 0 0
Activation of TRKA receptors R-HSA-187015 1.782680e-04 3.749 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.104306e-04 3.677 0 0
Growth hormone receptor signaling R-HSA-982772 2.784189e-04 3.555 0 0
Interleukin-12 signaling R-HSA-9020591 2.980128e-04 3.526 0 0
Signaling by Leptin R-HSA-2586552 3.826704e-04 3.417 0 0
M Phase R-HSA-68886 3.900543e-04 3.409 0 0
Interleukin-2 signaling R-HSA-9020558 4.742667e-04 3.324 0 0
RNA Polymerase II Transcription R-HSA-73857 4.983852e-04 3.302 0 0
Signaling by Interleukins R-HSA-449147 5.334565e-04 3.273 0 0
Cell Cycle, Mitotic R-HSA-69278 5.373385e-04 3.270 0 0
Signaling by Erythropoietin R-HSA-9006335 5.624680e-04 3.250 0 0
Regulation of gene expression in beta cells R-HSA-210745 5.624680e-04 3.250 0 0
PIP3 activates AKT signaling R-HSA-1257604 5.764550e-04 3.239 0 0
Interleukin-12 family signaling R-HSA-447115 5.987990e-04 3.223 0 0
Cellular responses to stress R-HSA-2262752 6.386888e-04 3.195 0 0
Downstream signal transduction R-HSA-186763 6.911111e-04 3.160 0 0
DNA Repair R-HSA-73894 7.839188e-04 3.106 0 0
RUNX3 regulates RUNX1-mediated transcription R-HSA-8951911 8.620838e-04 3.064 0 0
Signal regulatory protein family interactions R-HSA-391160 9.773437e-04 3.010 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 1.017760e-03 2.992 0 0
Signaling by PTK6 R-HSA-8848021 1.017760e-03 2.992 0 0
Generic Transcription Pathway R-HSA-212436 1.075620e-03 2.968 0 0
Erythropoietin activates RAS R-HSA-9027284 1.140624e-03 2.943 0 0
DCC mediated attractive signaling R-HSA-418885 1.140624e-03 2.943 0 0
Epigenetic regulation of gene expression R-HSA-212165 1.143882e-03 2.942 0 0
TRKA activation by NGF R-HSA-187042 1.337704e-03 2.874 0 0
Leishmania phagocytosis R-HSA-9664417 1.513979e-03 2.820 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 1.513979e-03 2.820 0 0
Parasite infection R-HSA-9664407 1.513979e-03 2.820 0 0
Interleukin-2 family signaling R-HSA-451927 1.658739e-03 2.780 0 0
Intracellular signaling by second messengers R-HSA-9006925 1.745501e-03 2.758 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 1.782862e-03 2.749 0 0
Signaling by ALK in cancer R-HSA-9700206 1.782862e-03 2.749 0 0
Regulation of gap junction activity R-HSA-191650 1.913003e-03 2.718 0 0
Regulation of signaling by CBL R-HSA-912631 2.212075e-03 2.655 0 0
Signaling by SCF-KIT R-HSA-1433557 2.226168e-03 2.652 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.386527e-03 2.622 0 0
IRS activation R-HSA-74713 2.585860e-03 2.587 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.077855e-03 2.512 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 3.107559e-03 2.508 0 0
NGF-independant TRKA activation R-HSA-187024 3.354185e-03 2.474 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 3.406417e-03 2.468 0 0
Signaling by KIT in disease R-HSA-9669938 3.406417e-03 2.468 0 0
Interleukin-20 family signaling R-HSA-8854691 3.755660e-03 2.425 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 4.697957e-03 2.328 0 0
Cell Cycle R-HSA-1640170 4.745016e-03 2.324 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 5.001158e-03 2.301 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 5.169051e-03 2.287 0 0
IFNG signaling activates MAPKs R-HSA-9732724 5.169051e-03 2.287 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 5.169051e-03 2.287 0 0
Gene expression (Transcription) R-HSA-74160 5.641461e-03 2.249 0 0
Regulation of beta-cell development R-HSA-186712 5.825449e-03 2.235 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 6.211578e-03 2.207 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 6.211578e-03 2.207 0 0
Interleukin-23 signaling R-HSA-9020933 6.211578e-03 2.207 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 6.211578e-03 2.207 0 0
Signaling by PDGF R-HSA-186797 6.775017e-03 2.169 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 8.557015e-03 2.068 0 0
PI3K/AKT activation R-HSA-198203 8.557015e-03 2.068 0 0
Signaling by NTRKs R-HSA-166520 8.794607e-03 2.056 0 0
Signal attenuation R-HSA-74749 8.557015e-03 2.068 0 0
Interleukin-27 signaling R-HSA-9020956 8.557015e-03 2.068 0 0
MAPK1 (ERK2) activation R-HSA-112411 7.341542e-03 2.134 0 0
MAPK3 (ERK1) activation R-HSA-110056 8.557015e-03 2.068 0 0
SARS-CoV-1-host interactions R-HSA-9692914 8.709935e-03 2.060 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.887448e-03 2.103 0 0
MITF-M-dependent gene expression R-HSA-9856651 9.290575e-03 2.032 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 7.821837e-03 2.107 0 0
RAF activation R-HSA-5673000 9.682760e-03 2.014 0 0
PECAM1 interactions R-HSA-210990 9.856097e-03 2.006 0 0
Signalling to ERKs R-HSA-187687 1.032966e-02 1.986 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.050183e-02 1.979 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.050183e-02 1.979 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.050183e-02 1.979 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.050183e-02 1.979 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.050183e-02 1.979 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.050183e-02 1.979 0 0
GPVI-mediated activation cascade R-HSA-114604 1.100110e-02 1.959 0 0
Sema4D mediated inhibition of cell attachment and migration R-HSA-416550 1.123692e-02 1.949 0 0
NFE2L2 regulates pentose phosphate pathway genes R-HSA-9818028 1.123692e-02 1.949 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.147541e-02 1.940 0 0
Interferon gamma signaling R-HSA-877300 1.177195e-02 1.929 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.201009e-02 1.920 0 0
Interferon alpha/beta signaling R-HSA-909733 1.241315e-02 1.906 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.269764e-02 1.896 0 0
Interleukin-35 Signalling R-HSA-8984722 1.269764e-02 1.896 0 0
Signaling by LTK R-HSA-9842663 1.269764e-02 1.896 0 0
Neutrophil degranulation R-HSA-6798695 1.317204e-02 1.880 0 0
Interleukin-6 signaling R-HSA-1059683 1.423646e-02 1.847 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 1.423646e-02 1.847 0 0
Signaling by RAF1 mutants R-HSA-9656223 1.555287e-02 1.808 0 0
Prolactin receptor signaling R-HSA-1170546 1.585158e-02 1.800 0 0
InlB-mediated entry of Listeria monocytogenes into host cell R-HSA-8875360 1.754127e-02 1.756 0 0
Axon guidance R-HSA-422475 1.760554e-02 1.754 0 0
Netrin-1 signaling R-HSA-373752 1.816986e-02 1.741 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.850511e-02 1.733 0 0
Prolonged ERK activation events R-HSA-169893 1.930378e-02 1.714 0 0
SARS-CoV Infections R-HSA-9679506 1.986780e-02 1.702 0 0
Signaling downstream of RAS mutants R-HSA-9649948 2.004216e-02 1.698 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 2.004216e-02 1.698 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 2.004216e-02 1.698 0 0
Signaling by RAS mutants R-HSA-6802949 2.004216e-02 1.698 0 0
Apoptotic execution phase R-HSA-75153 2.004216e-02 1.698 0 0
Drug-mediated inhibition of MET activation R-HSA-9734091 2.089402e-02 1.680 0 0
SARS-CoV-1 targets PDZ proteins in cell-cell junction R-HSA-9692912 2.089402e-02 1.680 0 0
EPH-Ephrin signaling R-HSA-2682334 2.363162e-02 1.627 0 0
Platelet sensitization by LDL R-HSA-432142 2.501148e-02 1.602 0 0
Nephron development R-HSA-9831926 2.501148e-02 1.602 0 0
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition R-HSA-9926550 2.501148e-02 1.602 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 2.534686e-02 1.596 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 2.692752e-02 1.570 0 0
Nervous system development R-HSA-9675108 2.706040e-02 1.568 0 0
NTRK3 as a dependence receptor R-HSA-9603505 3.117770e-02 1.506 0 0
NTF3 activates NTRK2 (TRKB) signaling R-HSA-9025046 4.135400e-02 1.383 0 0
BDNF activates NTRK2 (TRKB) signaling R-HSA-9024909 4.135400e-02 1.383 0 0
NTF4 activates NTRK2 (TRKB) signaling R-HSA-9026357 4.135400e-02 1.383 0 0
NTF3 activates NTRK3 signaling R-HSA-9034013 4.135400e-02 1.383 0 0
Negative regulation of MET activity R-HSA-6807004 2.915038e-02 1.535 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 3.354151e-02 1.474 0 0
Interleukin-6 family signaling R-HSA-6783589 4.057451e-02 1.392 0 0
Dectin-2 family R-HSA-5621480 3.216993e-02 1.493 0 0
Transport of connexins along the secretory pathway R-HSA-190827 3.117770e-02 1.506 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 4.135400e-02 1.383 0 0
Signalling to RAS R-HSA-167044 3.131519e-02 1.504 0 0
Oligomerization of connexins into connexons R-HSA-190704 3.117770e-02 1.506 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 4.057451e-02 1.392 0 0
Leishmania infection R-HSA-9658195 4.169364e-02 1.380 0 0
Parasitic Infection Pathways R-HSA-9824443 4.169364e-02 1.380 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 3.582782e-02 1.446 0 0
Potential therapeutics for SARS R-HSA-9679191 3.371200e-02 1.472 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 2.831670e-02 1.548 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 3.354151e-02 1.474 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 3.820504e-02 1.418 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 4.291364e-02 1.367 0 0
Tight junction interactions R-HSA-420029 4.303197e-02 1.366 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 4.303197e-02 1.366 0 0
Sema4D in semaphorin signaling R-HSA-400685 4.303197e-02 1.366 0 0
Interleukin-7 signaling R-HSA-1266695 4.303197e-02 1.366 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 4.548670e-02 1.342 0 0
MET activates PTK2 signaling R-HSA-8874081 4.554362e-02 1.342 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.554362e-02 1.342 0 0
MECP2 regulates neuronal receptors and channels R-HSA-9022699 4.554362e-02 1.342 0 0
Hemostasis R-HSA-109582 4.685227e-02 1.329 0 0
Innate Immune System R-HSA-168249 4.770941e-02 1.321 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 4.810805e-02 1.318 0 0
SARS-CoV-2-host interactions R-HSA-9705683 4.900252e-02 1.310 0 0
PLC-gamma1 signalling R-HSA-167021 5.142402e-02 1.289 0 0
Activated NTRK3 signals through PLCG1 R-HSA-9034793 5.142402e-02 1.289 0 0
MET interacts with TNS proteins R-HSA-8875513 5.142402e-02 1.289 0 0
Signalling to STAT3 R-HSA-198745 5.142402e-02 1.289 0 0
MET activates PTPN11 R-HSA-8865999 5.142402e-02 1.289 0 0
STAT6-mediated induction of chemokines R-HSA-3249367 5.142402e-02 1.289 0 0
MET activates STAT3 R-HSA-8875791 5.142402e-02 1.289 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 5.210723e-02 1.283 0 0
Cellular response to heat stress R-HSA-3371556 5.583821e-02 1.253 0 0
SARS-CoV-1 Infection R-HSA-9678108 5.597492e-02 1.252 0 0
Activated NTRK2 signals through PLCG1 R-HSA-9026527 6.138889e-02 1.212 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 6.138889e-02 1.212 0 0
RUNX2 regulates genes involved in differentiation of myeloid cells R-HSA-8941333 6.138889e-02 1.212 0 0
FLT3 signaling through SRC family kinases R-HSA-9706374 6.138889e-02 1.212 0 0
Integrin signaling R-HSA-354192 6.452802e-02 1.190 0 0
Signaling by MET R-HSA-6806834 6.721824e-02 1.173 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 7.036407e-02 1.153 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 7.036407e-02 1.153 0 0
RUNX1 regulates transcription of genes involved in interleukin signaling R-HSA-8939247 7.124968e-02 1.147 0 0
NTRK2 activates RAC1 R-HSA-9032759 7.124968e-02 1.147 0 0
Reelin signalling pathway R-HSA-8866376 7.124968e-02 1.147 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 7.334456e-02 1.135 0 0
HSF1 activation R-HSA-3371511 7.636510e-02 1.117 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.645150e-02 1.117 0 0
mRNA Splicing - Major Pathway R-HSA-72163 7.654870e-02 1.116 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 7.942455e-02 1.100 0 0
Signalling to p38 via RIT and RIN R-HSA-187706 8.100748e-02 1.091 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 8.100748e-02 1.091 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 8.100748e-02 1.091 0 0
Negative feedback regulation of MAPK pathway R-HSA-5674499 8.100748e-02 1.091 0 0
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components R-HSA-446388 8.100748e-02 1.091 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 8.100748e-02 1.091 0 0
Epithelial-Mesenchymal Transition (EMT) during gastrulation R-HSA-9758919 8.100748e-02 1.091 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 8.147446e-02 1.089 0 0
RUNX1 regulates transcription of genes involved in WNT signaling R-HSA-8939256 9.066336e-02 1.043 0 0
STAT5 Activation R-HSA-9645135 9.066336e-02 1.043 0 0
Activated NTRK2 signals through CDK5 R-HSA-9032845 1.002184e-01 0.999 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 1.002184e-01 0.999 0 0
SOS-mediated signalling R-HSA-112412 1.002184e-01 0.999 0 0
Activated NTRK2 signals through FYN R-HSA-9032500 1.096736e-01 0.960 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.096736e-01 0.960 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 1.096736e-01 0.960 0 0
Formation of annular gap junctions R-HSA-196025 1.096736e-01 0.960 0 0
MET receptor recycling R-HSA-8875656 1.096736e-01 0.960 0 0
ARMS-mediated activation R-HSA-170984 1.190300e-01 0.924 0 0
Gap junction degradation R-HSA-190873 1.190300e-01 0.924 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.282887e-01 0.892 0 0
Activated NTRK3 signals through RAS R-HSA-9034864 1.374506e-01 0.862 0 0
Activated NTRK2 signals through RAS R-HSA-9026519 1.465168e-01 0.834 0 0
MET activates RAS signaling R-HSA-8851805 1.554882e-01 0.808 0 0
Activated NTRK2 signals through FRS2 and FRS3 R-HSA-9028731 1.554882e-01 0.808 0 0
Scavenging by Class F Receptors R-HSA-3000484 1.554882e-01 0.808 0 0
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) R-HSA-8877330 1.643659e-01 0.784 0 0
MET promotes cell motility R-HSA-8875878 8.252175e-02 1.083 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 9.853571e-02 1.006 0 0
mRNA 3'-end processing R-HSA-72187 1.327940e-01 0.877 0 0
mRNA Splicing R-HSA-72172 9.009716e-02 1.045 0 0
RUNX1 regulates estrogen receptor mediated transcription R-HSA-8931987 1.002184e-01 0.999 0 0
Regulation of gene expression by Hypoxia-inducible Factor R-HSA-1234158 1.465168e-01 0.834 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 1.050166e-01 0.979 0 0
MAP2K and MAPK activation R-HSA-5674135 9.526610e-02 1.021 0 0
Regulation of CDH11 function R-HSA-9762292 1.282887e-01 0.892 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.374506e-01 0.862 0 0
Eukaryotic Translation Elongation R-HSA-156842 9.437882e-02 1.025 0 0
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes R-HSA-8939242 1.096736e-01 0.960 0 0
Gap junction trafficking and regulation R-HSA-157858 1.222448e-01 0.913 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.643659e-01 0.784 0 0
MET Receptor Activation R-HSA-6806942 9.066336e-02 1.043 0 0
SHC-related events triggered by IGF1R R-HSA-2428933 1.554882e-01 0.808 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.257378e-01 0.901 0 0
Conjugation of benzoate with glycine R-HSA-177135 1.374506e-01 0.862 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 1.554882e-01 0.808 0 0
Regulation of IFNG signaling R-HSA-877312 1.554882e-01 0.808 0 0
Conjugation of salicylate with glycine R-HSA-177128 1.554882e-01 0.808 0 0
Regulation of CDH1 Function R-HSA-9764561 1.508049e-01 0.822 0 0
FCGR activation R-HSA-2029481 9.646913e-02 1.016 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.183711e-01 0.927 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 1.567493e-01 0.805 0 0
Interleukin-21 signaling R-HSA-9020958 1.190300e-01 0.924 0 0
Frs2-mediated activation R-HSA-170968 1.643659e-01 0.784 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 8.754632e-02 1.058 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 1.085285e-01 0.964 0 0
FCERI mediated MAPK activation R-HSA-2871796 1.443613e-01 0.841 0 0
VLDL clearance R-HSA-8964046 1.002184e-01 0.999 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.374506e-01 0.862 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.229573e-01 0.910 0 0
Smooth Muscle Contraction R-HSA-445355 1.363555e-01 0.865 0 0
Interleukin-9 signaling R-HSA-8985947 1.096736e-01 0.960 0 0
DAP12 interactions R-HSA-2172127 1.051679e-01 0.978 0 0
Degradation of CDH1 R-HSA-9766229 1.222448e-01 0.913 0 0
Interleukin-15 signaling R-HSA-8983432 1.554882e-01 0.808 0 0
Generation of second messenger molecules R-HSA-202433 8.882500e-02 1.051 0 0
Negative regulation of MAPK pathway R-HSA-5675221 9.526610e-02 1.021 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 9.202885e-02 1.036 0 0
Co-stimulation by CD28 R-HSA-389356 1.187765e-01 0.925 0 0
Interferon Signaling R-HSA-913531 1.374696e-01 0.862 0 0
RUNX3 regulates p14-ARF R-HSA-8951936 1.554882e-01 0.808 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 1.643659e-01 0.784 0 0
Platelet activation, signaling and aggregation R-HSA-76002 9.285224e-02 1.032 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.190300e-01 0.924 0 0
Kinesins R-HSA-983189 1.618330e-01 0.791 0 0
Glycogen metabolism R-HSA-8982491 8.882500e-02 1.051 0 0
TCR signaling R-HSA-202403 1.395015e-01 0.855 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 1.085285e-01 0.964 0 0
Signaling by EGFR R-HSA-177929 1.471637e-01 0.832 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.505813e-01 0.822 0 0
RSV-host interactions R-HSA-9833110 1.252745e-01 0.902 0 0
FLT3 Signaling R-HSA-9607240 9.202885e-02 1.036 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 1.327940e-01 0.877 0 0
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes R-HSA-9615017 9.526610e-02 1.021 0 0
Cyclin D associated events in G1 R-HSA-69231 1.051679e-01 0.978 0 0
G1 Phase R-HSA-69236 1.051679e-01 0.978 0 0
Dissolution of Fibrin Clot R-HSA-75205 1.374506e-01 0.862 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 9.693803e-02 1.014 0 0
Apoptosis R-HSA-109581 1.242819e-01 0.906 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 1.655413e-01 0.781 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 1.655413e-01 0.781 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 1.720306e-01 0.764 0 0
Semaphorin interactions R-HSA-373755 1.730020e-01 0.762 0 0
Retrograde neurotrophin signalling R-HSA-177504 1.731508e-01 0.762 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.731508e-01 0.762 0 0
Regulation of KIT signaling R-HSA-1433559 1.731508e-01 0.762 0 0
IGF1R signaling cascade R-HSA-2428924 1.767530e-01 0.753 0 0
Insulin receptor signalling cascade R-HSA-74751 1.767530e-01 0.753 0 0
MHC class II antigen presentation R-HSA-2132295 1.772169e-01 0.751 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 1.805168e-01 0.743 0 0
Cellular response to hypoxia R-HSA-1234174 1.805168e-01 0.743 0 0
Developmental Cell Lineages R-HSA-9734767 1.811517e-01 0.742 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.818439e-01 0.740 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.818439e-01 0.740 0 0
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) R-HSA-2173791 1.818439e-01 0.740 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.818439e-01 0.740 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 1.818439e-01 0.740 0 0
Protein methylation R-HSA-8876725 1.818439e-01 0.740 0 0
Cell-extracellular matrix interactions R-HSA-446353 1.818439e-01 0.740 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 1.877169e-01 0.726 0 0
Kidney development R-HSA-9830369 1.880800e-01 0.726 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 1.904462e-01 0.720 0 0
Defective GALNT3 causes HFTC R-HSA-5083625 1.904462e-01 0.720 0 0
Defective GALNT12 causes CRCS1 R-HSA-5083636 1.904462e-01 0.720 0 0
Receptor-type tyrosine-protein phosphatases R-HSA-388844 1.904462e-01 0.720 0 0
Differentiation of T cells R-HSA-9945266 1.904462e-01 0.720 0 0
Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) R-HSA-9942503 1.904462e-01 0.720 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 1.956866e-01 0.708 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.968015e-01 0.706 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 1.989585e-01 0.701 0 0
STAT5 activation downstream of FLT3 ITD mutants R-HSA-9702518 1.989585e-01 0.701 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 1.989585e-01 0.701 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 1.989585e-01 0.701 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 2.021271e-01 0.694 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 2.064623e-01 0.685 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 2.071666e-01 0.684 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.073818e-01 0.683 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 2.073818e-01 0.683 0 0
Defective C1GALT1C1 causes TNPS R-HSA-5083632 2.073818e-01 0.683 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 2.073818e-01 0.683 0 0
Signaling by Hippo R-HSA-2028269 2.073818e-01 0.683 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 2.102889e-01 0.677 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 2.110095e-01 0.676 0 0
Programmed Cell Death R-HSA-5357801 2.152175e-01 0.667 0 0
Transport of connexons to the plasma membrane R-HSA-190872 2.157171e-01 0.666 0 0
Chaperone Mediated Autophagy R-HSA-9613829 2.157171e-01 0.666 0 0
GAB1 signalosome R-HSA-180292 2.157171e-01 0.666 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.157171e-01 0.666 0 0
UCH proteinases R-HSA-5689603 2.225789e-01 0.653 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.239652e-01 0.650 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 2.239652e-01 0.650 0 0
Conjugation of carboxylic acids R-HSA-159424 2.239652e-01 0.650 0 0
Amino Acid conjugation R-HSA-156587 2.239652e-01 0.650 0 0
Rap1 signalling R-HSA-392517 2.239652e-01 0.650 0 0
Other interleukin signaling R-HSA-449836 2.239652e-01 0.650 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 2.321271e-01 0.634 0 0
Co-inhibition by CTLA4 R-HSA-389513 2.321271e-01 0.634 0 0
Basigin interactions R-HSA-210991 2.402037e-01 0.619 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 2.458516e-01 0.609 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.481957e-01 0.605 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 2.561043e-01 0.592 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 2.561043e-01 0.592 0 0
LDL clearance R-HSA-8964038 2.561043e-01 0.592 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.639301e-01 0.579 0 0
Termination of O-glycan biosynthesis R-HSA-977068 2.639301e-01 0.579 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 2.639301e-01 0.579 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 2.639301e-01 0.579 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 2.648276e-01 0.577 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 2.676640e-01 0.572 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 2.696171e-01 0.569 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.716740e-01 0.566 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 2.716740e-01 0.566 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.716740e-01 0.566 0 0
Deadenylation of mRNA R-HSA-429947 2.716740e-01 0.566 0 0
Peptide chain elongation R-HSA-156902 2.731071e-01 0.564 0 0
Membrane Trafficking R-HSA-199991 2.764505e-01 0.558 0 0
HDMs demethylate histones R-HSA-3214842 2.793370e-01 0.554 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.793370e-01 0.554 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 2.847858e-01 0.545 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.869198e-01 0.542 0 0
Cell surface interactions at the vascular wall R-HSA-202733 2.882943e-01 0.540 0 0
Signaling by Insulin receptor R-HSA-74752 2.925627e-01 0.534 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 2.944233e-01 0.531 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 2.944233e-01 0.531 0 0
Cristae formation R-HSA-8949613 2.944233e-01 0.531 0 0
Insulin receptor recycling R-HSA-77387 3.018483e-01 0.520 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.091956e-01 0.510 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 3.091956e-01 0.510 0 0
Endosomal Sorting Complex Required For Transport (ESCRT) R-HSA-917729 3.091956e-01 0.510 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 3.119511e-01 0.506 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 3.119511e-01 0.506 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.164660e-01 0.500 0 0
DAP12 signaling R-HSA-2424491 3.164660e-01 0.500 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.164660e-01 0.500 1 1
Signaling by ERBB2 in Cancer R-HSA-1227990 3.164660e-01 0.500 0 0
FOXO-mediated transcription R-HSA-9614085 3.235333e-01 0.490 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.236604e-01 0.490 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 3.236604e-01 0.490 0 0
EGFR downregulation R-HSA-182971 3.236604e-01 0.490 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 3.236604e-01 0.490 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.236604e-01 0.490 0 0
Leishmania parasite growth and survival R-HSA-9664433 3.306588e-01 0.481 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 3.306588e-01 0.481 0 0
Developmental Lineage of Multipotent Pancreatic Progenitor Cells R-HSA-9937080 3.307794e-01 0.480 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 3.307794e-01 0.480 0 0
G0 and Early G1 R-HSA-1538133 3.307794e-01 0.480 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 3.312280e-01 0.480 0 0
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known R-HSA-8939243 3.378240e-01 0.471 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 3.378240e-01 0.471 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.378240e-01 0.471 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.447949e-01 0.462 0 0
Vpu mediated degradation of CD4 R-HSA-180534 3.447949e-01 0.462 0 0
Miscellaneous transport and binding events R-HSA-5223345 3.447949e-01 0.462 0 0
NPAS4 regulates expression of target genes R-HSA-9768919 3.516928e-01 0.454 0 0
Gap junction assembly R-HSA-190861 3.516928e-01 0.454 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 3.516928e-01 0.454 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 3.516928e-01 0.454 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 3.516928e-01 0.454 0 0
Platelet homeostasis R-HSA-418346 3.541577e-01 0.451 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 3.585185e-01 0.445 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 3.585185e-01 0.445 0 0
Regulation of Apoptosis R-HSA-169911 3.585185e-01 0.445 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.617419e-01 0.442 0 0
Cellular response to chemical stress R-HSA-9711123 3.619008e-01 0.441 0 0
FLT3 signaling in disease R-HSA-9682385 3.652727e-01 0.437 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.652727e-01 0.437 0 0
Vif-mediated degradation of APOBEC3G R-HSA-180585 3.652727e-01 0.437 0 0
RET signaling R-HSA-8853659 3.652727e-01 0.437 0 0
Degradation of DVL R-HSA-4641258 3.719563e-01 0.430 0 0
Degradation of AXIN R-HSA-4641257 3.719563e-01 0.430 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 3.719563e-01 0.430 0 0
SLC-mediated transport of organic cations R-HSA-549127 3.719563e-01 0.430 0 0
Vesicle-mediated transport R-HSA-5653656 3.790217e-01 0.421 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 3.851142e-01 0.414 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 3.851142e-01 0.414 0 0
Stabilization of p53 R-HSA-69541 3.851142e-01 0.414 0 0
Plasma lipoprotein clearance R-HSA-8964043 3.851142e-01 0.414 0 0
Pentose phosphate pathway R-HSA-71336 3.851142e-01 0.414 0 0
Signaling by ALK R-HSA-201556 3.851142e-01 0.414 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 3.915900e-01 0.407 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 3.915900e-01 0.407 0 0
Attenuation phase R-HSA-3371568 3.915900e-01 0.407 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 3.915900e-01 0.407 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 3.915900e-01 0.407 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 3.915900e-01 0.407 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 3.979981e-01 0.400 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 3.979981e-01 0.400 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 3.979981e-01 0.400 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 3.979981e-01 0.400 0 0
HIV Transcription Initiation R-HSA-167161 4.043390e-01 0.393 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 4.043390e-01 0.393 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 4.043390e-01 0.393 0 0
Degradation of CRY and PER proteins R-HSA-9932298 4.043390e-01 0.393 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 4.043390e-01 0.393 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 4.043390e-01 0.393 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 4.043390e-01 0.393 0 0
Signaling by FGFR1 in disease R-HSA-5655302 4.043390e-01 0.393 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.101545e-01 0.387 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 4.168223e-01 0.380 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 4.168223e-01 0.380 0 0
Gap junction trafficking R-HSA-190828 4.229661e-01 0.374 0 0
Proteasome assembly R-HSA-9907900 4.229661e-01 0.374 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 4.229661e-01 0.374 0 0
Methylation R-HSA-156581 4.229661e-01 0.374 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 4.229661e-01 0.374 0 0
RMTs methylate histone arginines R-HSA-3214858 4.229661e-01 0.374 0 0
Formation of the cornified envelope R-HSA-6809371 4.283044e-01 0.368 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 4.290456e-01 0.367 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 4.290456e-01 0.367 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 4.290456e-01 0.367 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 4.290456e-01 0.367 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 4.290456e-01 0.367 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 4.290456e-01 0.367 0 0
Somitogenesis R-HSA-9824272 4.290456e-01 0.367 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 4.350613e-01 0.361 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.350613e-01 0.361 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.350613e-01 0.361 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 4.410141e-01 0.356 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.410141e-01 0.356 0 0
Retrograde transport at the Trans-Golgi-Network R-HSA-6811440 4.410141e-01 0.356 0 0
Gluconeogenesis R-HSA-70263 4.469045e-01 0.350 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 4.527332e-01 0.344 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 4.527332e-01 0.344 0 0
PI3K Cascade R-HSA-109704 4.585008e-01 0.339 0 0
Azathioprine ADME R-HSA-9748787 4.585008e-01 0.339 0 0
HSF1-dependent transactivation R-HSA-3371571 4.642080e-01 0.333 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 4.642080e-01 0.333 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 4.642080e-01 0.333 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.642080e-01 0.333 0 0
Transcriptional Regulation by NPAS4 R-HSA-9634815 4.698553e-01 0.328 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.698553e-01 0.328 0 0
Orc1 removal from chromatin R-HSA-68949 4.698553e-01 0.328 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 4.698553e-01 0.328 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 4.754435e-01 0.323 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.754435e-01 0.323 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.754435e-01 0.323 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.754435e-01 0.323 0 0
Translation initiation complex formation R-HSA-72649 4.809732e-01 0.318 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 4.809732e-01 0.318 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.809732e-01 0.318 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.864449e-01 0.313 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.864449e-01 0.313 0 0
Ribosome-associated quality control R-HSA-9948299 4.877082e-01 0.312 0 0
PTEN Regulation R-HSA-6807070 4.910832e-01 0.309 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.918592e-01 0.308 0 0
NRAGE signals death through JNK R-HSA-193648 4.918592e-01 0.308 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 4.918592e-01 0.308 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 4.918592e-01 0.308 0 0
IRS-mediated signalling R-HSA-112399 4.972168e-01 0.303 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 4.972168e-01 0.303 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 5.025182e-01 0.299 0 0
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux R-HSA-9029569 5.025182e-01 0.299 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 5.044433e-01 0.297 0 0
Clathrin-mediated endocytosis R-HSA-8856828 5.077480e-01 0.294 0 0
Peroxisomal protein import R-HSA-9033241 5.077641e-01 0.294 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.077641e-01 0.294 0 0
Amino acid transport across the plasma membrane R-HSA-352230 5.077641e-01 0.294 0 0
Post-translational protein modification R-HSA-597592 5.103137e-01 0.292 0 0
FCERI mediated NF-kB activation R-HSA-2871837 5.110385e-01 0.292 0 0
Signaling by ERBB2 R-HSA-1227986 5.129550e-01 0.290 1 0
RAB geranylgeranylation R-HSA-8873719 5.129550e-01 0.290 0 0
Regulation of PTEN gene transcription R-HSA-8943724 5.129550e-01 0.290 0 0
Metabolism of polyamines R-HSA-351202 5.129550e-01 0.290 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 5.180914e-01 0.286 0 0
Endogenous sterols R-HSA-211976 5.180914e-01 0.286 0 0
Formation of paraxial mesoderm R-HSA-9793380 5.180914e-01 0.286 0 0
NCAM signaling for neurite out-growth R-HSA-375165 5.231740e-01 0.281 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 5.231740e-01 0.281 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.231740e-01 0.281 0 0
Mitochondrial protein import R-HSA-1268020 5.231740e-01 0.281 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 5.231740e-01 0.281 0 0
Gastrulation R-HSA-9758941 5.272745e-01 0.278 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 5.282033e-01 0.277 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 5.282033e-01 0.277 0 0
Complex I biogenesis R-HSA-6799198 5.282033e-01 0.277 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 5.282033e-01 0.277 0 0
CD22 mediated BCR regulation R-HSA-5690714 5.331798e-01 0.273 0 0
Xenobiotics R-HSA-211981 5.331798e-01 0.273 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 5.368411e-01 0.270 0 0
Protein localization R-HSA-9609507 5.400005e-01 0.268 0 0
AURKA Activation by TPX2 R-HSA-8854518 5.429769e-01 0.265 0 0
SLC-mediated transport of amino acids R-HSA-9958863 5.477986e-01 0.261 0 0
O-linked glycosylation of mucins R-HSA-913709 5.525696e-01 0.258 0 0
Transcription of the HIV genome R-HSA-167172 5.525696e-01 0.258 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.525696e-01 0.258 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 5.619621e-01 0.250 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.619621e-01 0.250 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 5.619621e-01 0.250 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 5.619621e-01 0.250 0 0
Diseases associated with O-glycosylation of proteins R-HSA-3906995 5.665846e-01 0.247 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.665846e-01 0.247 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.665846e-01 0.247 0 0
Hedgehog 'on' state R-HSA-5632684 5.665846e-01 0.247 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 5.711585e-01 0.243 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 5.711585e-01 0.243 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 5.711585e-01 0.243 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 5.756845e-01 0.240 0 0
Switching of origins to a post-replicative state R-HSA-69052 5.756845e-01 0.240 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 5.756845e-01 0.240 0 0
Aspirin ADME R-HSA-9749641 5.756845e-01 0.240 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 5.801630e-01 0.236 0 0
Signaling by NOTCH4 R-HSA-9013694 5.801630e-01 0.236 0 0
Signaling by ERBB4 R-HSA-1236394 5.801630e-01 0.236 0 0
Signaling by FGFR in disease R-HSA-1226099 5.801630e-01 0.236 0 0
Centrosome maturation R-HSA-380287 5.845945e-01 0.233 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 5.845945e-01 0.233 0 0
NR1H2 and NR1H3-mediated signaling R-HSA-9024446 5.933185e-01 0.227 0 0
Nuclear Receptor transcription pathway R-HSA-383280 5.976120e-01 0.224 0 0
Interleukin-10 signaling R-HSA-6783783 5.976120e-01 0.224 0 0
G alpha (12/13) signalling events R-HSA-416482 5.976120e-01 0.224 0 0
ABC transporter disorders R-HSA-5619084 5.976120e-01 0.224 0 0
PCP/CE pathway R-HSA-4086400 5.976120e-01 0.224 0 0
Integrin cell surface interactions R-HSA-216083 5.976120e-01 0.224 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 6.060641e-01 0.217 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 6.184126e-01 0.209 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 6.224426e-01 0.206 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.224426e-01 0.206 0 0
Protein-protein interactions at synapses R-HSA-6794362 6.264303e-01 0.203 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 6.264303e-01 0.203 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 6.303761e-01 0.200 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 6.303761e-01 0.200 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.342805e-01 0.198 0 0
Chaperonin-mediated protein folding R-HSA-390466 6.381439e-01 0.195 0 0
G2/M Transition R-HSA-69275 6.384691e-01 0.195 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 6.419668e-01 0.192 0 0
Mitotic G2-G2/M phases R-HSA-453274 6.437175e-01 0.191 0 0
ER-Phagosome pathway R-HSA-1236974 6.457494e-01 0.190 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 6.494924e-01 0.187 0 0
Downstream TCR signaling R-HSA-202424 6.494924e-01 0.187 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 6.531960e-01 0.185 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 6.568607e-01 0.183 0 0
Protein folding R-HSA-391251 6.604869e-01 0.180 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 6.604869e-01 0.180 0 0
Mitochondrial protein degradation R-HSA-9837999 6.676255e-01 0.175 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 6.711386e-01 0.173 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.746148e-01 0.171 0 0
Eukaryotic Translation Termination R-HSA-72764 6.746148e-01 0.171 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 6.746148e-01 0.171 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.780544e-01 0.169 0 0
Signaling by ROBO receptors R-HSA-376176 6.811870e-01 0.167 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.814580e-01 0.167 0 0
Metabolism of RNA R-HSA-8953854 6.868782e-01 0.163 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 6.881581e-01 0.162 0 0
Keratinization R-HSA-6805567 6.906229e-01 0.161 0 0
Hedgehog 'off' state R-HSA-5610787 6.914554e-01 0.160 0 0
Glycolysis R-HSA-70171 6.914554e-01 0.160 0 0
ABC-family proteins mediated transport R-HSA-382556 6.914554e-01 0.160 0 0
Selenocysteine synthesis R-HSA-2408557 6.947180e-01 0.158 0 0
Interleukin-1 signaling R-HSA-9020702 6.947180e-01 0.158 0 0
PI Metabolism R-HSA-1483255 6.979464e-01 0.156 0 0
Viral mRNA Translation R-HSA-192823 7.011408e-01 0.154 0 0
Translation R-HSA-72766 7.020503e-01 0.154 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 7.043016e-01 0.152 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.043016e-01 0.152 0 0
Muscle contraction R-HSA-397014 7.043472e-01 0.152 0 0
Nucleotide Excision Repair R-HSA-5696398 7.105239e-01 0.148 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 7.166160e-01 0.145 0 0
Synthesis of DNA R-HSA-69239 7.166160e-01 0.145 0 0
Drug ADME R-HSA-9748784 7.175645e-01 0.144 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 7.196141e-01 0.143 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 7.196141e-01 0.143 0 0
Antigen processing-Cross presentation R-HSA-1236975 7.196141e-01 0.143 0 0
Stimuli-sensing channels R-HSA-2672351 7.196141e-01 0.143 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.312944e-01 0.136 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.312944e-01 0.136 0 0
HIV Infection R-HSA-162906 7.364620e-01 0.133 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 7.424909e-01 0.129 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 7.427041e-01 0.129 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 7.452168e-01 0.128 0 0
Metabolism of proteins R-HSA-392499 7.459763e-01 0.127 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.479140e-01 0.126 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.479140e-01 0.126 0 0
Glucose metabolism R-HSA-70326 7.505828e-01 0.125 0 0
Rab regulation of trafficking R-HSA-9007101 7.505828e-01 0.125 0 0
Mitochondrial biogenesis R-HSA-1592230 7.505828e-01 0.125 0 0
Phase II - Conjugation of compounds R-HSA-156580 7.599839e-01 0.119 0 0
Host Interactions of HIV factors R-HSA-162909 7.684941e-01 0.114 0 0
G1/S Transition R-HSA-69206 7.733725e-01 0.112 0 0
Platelet degranulation R-HSA-114608 7.781488e-01 0.109 0 0
Adipogenesis R-HSA-9843745 7.896561e-01 0.103 0 0
Circadian clock R-HSA-9909396 7.918854e-01 0.101 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 7.940911e-01 0.100 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 8.026841e-01 0.095 0 0
O-linked glycosylation R-HSA-5173105 8.047761e-01 0.094 0 0
Signaling by Hedgehog R-HSA-5358351 8.068460e-01 0.093 0 0
Bacterial Infection Pathways R-HSA-9824439 8.111802e-01 0.091 0 0
Late Phase of HIV Life Cycle R-HSA-162599 8.168727e-01 0.088 0 0
ER to Golgi Anterograde Transport R-HSA-199977 8.263819e-01 0.083 0 0
S Phase R-HSA-69242 8.282240e-01 0.082 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 8.299699e-01 0.081 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 8.318501e-01 0.080 0 0
Interleukin-1 family signaling R-HSA-446652 8.354000e-01 0.078 0 0
Death Receptor Signaling R-HSA-73887 8.388755e-01 0.076 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 8.405858e-01 0.075 0 0
PPARA activates gene expression R-HSA-1989781 8.405858e-01 0.075 0 0
Autophagy R-HSA-9612973 8.422780e-01 0.075 0 0
HIV Life Cycle R-HSA-162587 8.439524e-01 0.074 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.439524e-01 0.074 0 0
Cellular response to starvation R-HSA-9711097 8.456091e-01 0.073 0 0
Signaling by TGFB family members R-HSA-9006936 8.488702e-01 0.071 0 0
Separation of Sister Chromatids R-HSA-2467813 8.551884e-01 0.068 0 0
Selenoamino acid metabolism R-HSA-2408522 8.551884e-01 0.068 0 0
Cytochrome P450 - arranged by substrate type R-HSA-211897 8.597541e-01 0.066 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 8.656198e-01 0.063 0 0
Organelle biogenesis and maintenance R-HSA-1852241 8.759849e-01 0.058 0 0
Respiratory electron transport R-HSA-611105 8.766295e-01 0.057 0 0
Influenza Infection R-HSA-168255 8.779410e-01 0.057 0 0
Diseases of glycosylation R-HSA-3781865 8.842939e-01 0.053 0 0
Extracellular matrix organization R-HSA-1474244 8.870004e-01 0.052 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 8.891386e-01 0.051 0 0
Ion channel transport R-HSA-983712 8.903179e-01 0.050 0 0
Cilium Assembly R-HSA-5617833 8.914848e-01 0.050 0 0
Mitotic Prometaphase R-HSA-68877 8.949118e-01 0.048 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 8.962253e-01 0.048 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 9.045606e-01 0.044 0 0
Mitotic Anaphase R-HSA-68882 9.187235e-01 0.037 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 9.195897e-01 0.036 0 0
Neddylation R-HSA-8951664 9.229636e-01 0.035 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.284770e-01 0.032 0 0
Biological oxidations R-HSA-211859 9.288826e-01 0.032 0 0
rRNA processing R-HSA-72312 9.315335e-01 0.031 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.367626e-01 0.028 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.417120e-01 0.026 0 0
Transport of small molecules R-HSA-382551 9.567236e-01 0.019 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.582256e-01 0.019 0 0
Phospholipid metabolism R-HSA-1483257 9.652099e-01 0.015 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 9.656350e-01 0.015 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.912815e-01 0.004 0 0
Diseases of metabolism R-HSA-5668914 9.917421e-01 0.004 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.917778e-01 0.004 0 0
Neuronal System R-HSA-112316 9.947124e-01 0.002 0 0
GPCR downstream signalling R-HSA-388396 9.998172e-01 0.000 0 0
Signaling by GPCR R-HSA-372790 9.999275e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.999990e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways

Motif of predicted substrate sequence

Reactome pathways of predicted substrates

Download
name reactome_id p -log10p ref_path ref_path_lowest
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 1.110223e-16 15.955 0 0
L1CAM interactions R-HSA-373760 3.985701e-14 13.399 0 0
Cellular response to heat stress R-HSA-3371556 7.693846e-14 13.114 0 0
Gap junction trafficking and regulation R-HSA-157858 1.079137e-13 12.967 0 0
Axon guidance R-HSA-422475 9.781065e-14 13.010 0 0
Cellular responses to stimuli R-HSA-8953897 8.193446e-14 13.087 0 0
Attenuation phase R-HSA-3371568 1.900702e-13 12.721 0 0
HSF1-dependent transactivation R-HSA-3371571 1.707523e-13 12.768 0 0
Cellular responses to stress R-HSA-2262752 2.954303e-13 12.530 0 0
Nervous system development R-HSA-9675108 5.875300e-13 12.231 0 0
Gap junction trafficking R-HSA-190828 6.664669e-13 12.176 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.922063e-13 12.003 0 0
Recycling pathway of L1 R-HSA-437239 1.333489e-12 11.875 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.529443e-12 11.815 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 2.681744e-12 11.572 0 0
PKR-mediated signaling R-HSA-9833482 2.436273e-12 11.613 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 3.438916e-12 11.464 0 0
Aggrephagy R-HSA-9646399 4.091949e-12 11.388 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 2.565725e-11 10.591 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 4.363987e-11 10.360 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 1.145593e-10 9.941 0 0
Selective autophagy R-HSA-9663891 1.145593e-10 9.941 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 1.138838e-10 9.944 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 1.251005e-10 9.903 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 1.505309e-10 9.822 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.501490e-10 9.823 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 2.488991e-10 9.604 0 0
Gap junction assembly R-HSA-190861 4.008538e-10 9.397 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 5.141154e-10 9.289 0 0
HSF1 activation R-HSA-3371511 6.303809e-10 9.200 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 8.030726e-10 9.095 0 0
Autophagy R-HSA-9612973 3.336531e-09 8.477 0 0
COPI-mediated anterograde transport R-HSA-6807878 4.113135e-09 8.386 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 6.414949e-09 8.193 0 0
MHC class II antigen presentation R-HSA-2132295 8.951657e-09 8.048 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 9.105346e-09 8.041 0 0
Interferon Signaling R-HSA-913531 1.057106e-08 7.976 0 0
Post NMDA receptor activation events R-HSA-438064 1.207300e-08 7.918 0 0
Protein folding R-HSA-391251 2.327564e-08 7.633 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 2.757270e-08 7.560 0 0
Kinesins R-HSA-983189 4.594457e-08 7.338 0 0
Macroautophagy R-HSA-1632852 5.136550e-08 7.289 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 4.946400e-08 7.306 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 6.983539e-08 7.156 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.030320e-07 6.987 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.172059e-07 6.931 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 1.443548e-07 6.841 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.808217e-07 6.743 0 0
G2/M Transition R-HSA-69275 1.957777e-07 6.708 0 0
EPH-Ephrin signaling R-HSA-2682334 2.127238e-07 6.672 0 0
Mitotic G2-G2/M phases R-HSA-453274 2.211495e-07 6.655 0 0
Mitotic Prometaphase R-HSA-68877 2.980971e-07 6.526 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.550536e-07 6.342 0 0
Immune System R-HSA-168256 5.224444e-07 6.282 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.763382e-07 6.239 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.176024e-06 5.930 0 0
Intraflagellar transport R-HSA-5620924 1.287073e-06 5.890 0 0
Gluconeogenesis R-HSA-70263 1.287073e-06 5.890 0 0
Cilium Assembly R-HSA-5617833 1.407678e-06 5.851 0 0
Separation of Sister Chromatids R-HSA-2467813 1.685784e-06 5.773 0 0
Smooth Muscle Contraction R-HSA-445355 2.407645e-06 5.618 0 0
Viral Infection Pathways R-HSA-9824446 2.491368e-06 5.604 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 2.704051e-06 5.568 0 0
Infectious disease R-HSA-5663205 5.376501e-06 5.270 0 0
Mitotic Anaphase R-HSA-68882 5.598334e-06 5.252 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 5.869683e-06 5.231 0 0
Semaphorin interactions R-HSA-373755 7.223914e-06 5.141 0 0
Developmental Biology R-HSA-1266738 8.974787e-06 5.047 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 1.325420e-05 4.878 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.355348e-05 4.868 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 1.385337e-05 4.858 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 1.607527e-05 4.794 0 0
Hemostasis R-HSA-109582 1.630144e-05 4.788 0 0
Cell-Cell communication R-HSA-1500931 1.816890e-05 4.741 0 0
Translation initiation complex formation R-HSA-72649 2.680044e-05 4.572 0 0
Signaling by VEGF R-HSA-194138 2.700760e-05 4.569 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 3.271472e-05 4.485 0 0
Regulation of CDH1 Function R-HSA-9764561 3.605119e-05 4.443 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 3.966224e-05 4.402 0 0
M Phase R-HSA-68886 4.497010e-05 4.347 0 0
HCMV Early Events R-HSA-9609690 4.708264e-05 4.327 0 0
Membrane Trafficking R-HSA-199991 4.970270e-05 4.304 0 0
Syndecan interactions R-HSA-3000170 5.515646e-05 4.258 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 5.603264e-05 4.252 0 0
Platelet activation, signaling and aggregation R-HSA-76002 6.101914e-05 4.215 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 6.246084e-05 4.204 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 6.246084e-05 4.204 0 0
Signaling by RAF1 mutants R-HSA-9656223 6.530228e-05 4.185 0 0
Vesicle-mediated transport R-HSA-5653656 7.152595e-05 4.146 0 0
Cell Cycle R-HSA-1640170 6.622139e-05 4.179 0 0
Organelle biogenesis and maintenance R-HSA-1852241 7.783681e-05 4.109 0 0
AURKA Activation by TPX2 R-HSA-8854518 8.064338e-05 4.093 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.484329e-05 4.071 0 0
EPHB-mediated forward signaling R-HSA-3928662 9.018759e-05 4.045 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 9.603057e-05 4.018 0 0
Muscle contraction R-HSA-397014 9.603057e-05 4.018 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.105973e-04 3.956 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.105973e-04 3.956 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.105973e-04 3.956 0 0
Signaling by RAS mutants R-HSA-6802949 1.105973e-04 3.956 0 0
Apoptotic execution phase R-HSA-75153 1.105973e-04 3.956 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 1.401890e-04 3.853 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.476346e-04 3.831 0 0
Glycolysis R-HSA-70171 1.625138e-04 3.789 0 0
Hedgehog 'off' state R-HSA-5610787 1.625138e-04 3.789 0 0
Centrosome maturation R-HSA-380287 1.625470e-04 3.789 0 0
Platelet degranulation R-HSA-114608 1.660875e-04 3.780 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 2.361347e-04 3.627 0 0
p130Cas linkage to MAPK signaling for integrins R-HSA-372708 2.570773e-04 3.590 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 2.754261e-04 3.560 0 0
Chaperone Mediated Autophagy R-HSA-9613829 3.038700e-04 3.517 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 3.016474e-04 3.521 0 0
Signal Transduction R-HSA-162582 2.771604e-04 3.557 1 0
Adaptive Immune System R-HSA-1280218 3.111476e-04 3.507 0 0
Signaling by Hedgehog R-HSA-5358351 3.142446e-04 3.503 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 3.604676e-04 3.443 0 0
HCMV Infection R-HSA-9609646 3.789795e-04 3.421 0 0
SARS-CoV Infections R-HSA-9679506 3.816092e-04 3.418 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 4.418605e-04 3.355 0 0
Disease R-HSA-1643685 4.625889e-04 3.335 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 4.654879e-04 3.332 0 0
Cell Cycle, Mitotic R-HSA-69278 4.795698e-04 3.319 0 0
Glucose metabolism R-HSA-70326 4.860262e-04 3.313 0 0
Formation of annular gap junctions R-HSA-196025 4.929154e-04 3.307 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 4.929154e-04 3.307 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 5.457033e-04 3.263 0 0
Gap junction degradation R-HSA-190873 6.335788e-04 3.198 0 0
Manipulation of host energy metabolism R-HSA-9636667 8.065171e-04 3.093 0 0
mRNA Splicing - Major Pathway R-HSA-72163 7.654617e-04 3.116 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 8.742411e-04 3.058 0 0
Transmission across Chemical Synapses R-HSA-112315 9.511649e-04 3.022 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 1.018226e-03 2.992 0 0
mRNA Splicing R-HSA-72172 1.114413e-03 2.953 0 0
Interaction between L1 and Ankyrins R-HSA-445095 1.158714e-03 2.936 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 1.184438e-03 2.926 1 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 1.362099e-03 2.866 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 1.410654e-03 2.851 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 1.410654e-03 2.851 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 1.410654e-03 2.851 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 1.435639e-03 2.843 0 0
Scavenging by Class F Receptors R-HSA-3000484 1.443096e-03 2.841 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 1.597479e-03 2.797 0 0
Oncogenic MAPK signaling R-HSA-6802957 1.866931e-03 2.729 0 0
Signal regulatory protein family interactions R-HSA-391160 2.014229e-03 2.696 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 2.538136e-03 2.595 0 0
Cap-dependent Translation Initiation R-HSA-72737 2.206487e-03 2.656 0 0
Integrin signaling R-HSA-354192 2.122076e-03 2.673 0 0
Eukaryotic Translation Initiation R-HSA-72613 2.206487e-03 2.656 0 0
Protein methylation R-HSA-8876725 2.345495e-03 2.630 0 0
Cell-extracellular matrix interactions R-HSA-446353 2.345495e-03 2.630 0 0
Potential therapeutics for SARS R-HSA-9679191 2.328330e-03 2.633 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 2.642042e-03 2.578 0 0
GRB2:SOS provides linkage to MAPK signaling for Integrins R-HSA-354194 2.708625e-03 2.567 0 0
Eukaryotic Translation Elongation R-HSA-156842 2.940553e-03 2.532 0 0
Asparagine N-linked glycosylation R-HSA-446203 3.261886e-03 2.487 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.262278e-03 2.486 0 0
Extracellular matrix organization R-HSA-1474244 3.413834e-03 2.467 0 0
Signaling by Interleukins R-HSA-449147 3.441415e-03 2.463 0 0
MET promotes cell motility R-HSA-8875878 3.531897e-03 2.452 0 0
MAP2K and MAPK activation R-HSA-5674135 4.761611e-03 2.322 0 0
Nephrin family interactions R-HSA-373753 5.034403e-03 2.298 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 5.108668e-03 2.292 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 5.155136e-03 2.288 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 5.155136e-03 2.288 0 0
RUNX1 regulates expression of components of tight junctions R-HSA-8935964 5.484779e-03 2.261 0 0
SARS-CoV-1-host interactions R-HSA-9692914 5.904775e-03 2.229 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 6.143225e-03 2.212 0 0
Signaling by ALK in cancer R-HSA-9700206 6.143225e-03 2.212 0 0
Platelet Aggregation (Plug Formation) R-HSA-76009 6.250548e-03 2.204 0 0
DAG and IP3 signaling R-HSA-1489509 6.250548e-03 2.204 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 6.665860e-03 2.176 0 0
mTORC1-mediated signalling R-HSA-166208 6.866226e-03 2.163 0 0
Metabolism of RNA R-HSA-8953854 6.902801e-03 2.161 0 0
Neuronal System R-HSA-112316 7.570039e-03 2.121 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 8.397178e-03 2.076 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 9.046309e-03 2.044 0 0
CHL1 interactions R-HSA-447041 8.418839e-03 2.075 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 8.418839e-03 2.075 0 0
Cell junction organization R-HSA-446728 8.214699e-03 2.085 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 9.817318e-03 2.008 0 0
Interleukin-23 signaling R-HSA-9020933 1.009672e-02 1.996 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 1.069969e-02 1.971 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 1.185179e-02 1.926 0 0
ALK mutants bind TKIs R-HSA-9700645 1.190981e-02 1.924 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 1.190981e-02 1.924 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.200218e-02 1.921 0 0
Apoptosis R-HSA-109581 1.228046e-02 1.911 0 0
Signaling by Erythropoietin R-HSA-9006335 1.251665e-02 1.903 0 0
Programmed Cell Death R-HSA-5357801 1.261273e-02 1.899 0 0
MET activates RAP1 and RAC1 R-HSA-8875555 1.385417e-02 1.858 0 0
CaMK IV-mediated phosphorylation of CREB R-HSA-111932 1.385417e-02 1.858 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 1.385417e-02 1.858 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 1.449959e-02 1.839 0 0
Neutrophil degranulation R-HSA-6798695 1.459562e-02 1.836 0 0
PLC beta mediated events R-HSA-112043 1.520314e-02 1.818 0 0
PECAM1 interactions R-HSA-210990 1.592597e-02 1.798 0 0
Developmental Cell Lineages R-HSA-9734767 1.626869e-02 1.789 0 0
Adherens junctions interactions R-HSA-418990 1.706962e-02 1.768 0 0
G-protein mediated events R-HSA-112040 1.994445e-02 1.700 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 2.019376e-02 1.695 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 2.043687e-02 1.690 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 2.043687e-02 1.690 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 2.043687e-02 1.690 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 2.043687e-02 1.690 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 2.081353e-02 1.682 0 0
SARS-CoV-2-host interactions R-HSA-9705683 2.119817e-02 1.674 0 0
Response of endothelial cells to shear stress R-HSA-9860931 2.129634e-02 1.672 0 0
CaM pathway R-HSA-111997 2.145989e-02 1.668 0 0
Calmodulin induced events R-HSA-111933 2.145989e-02 1.668 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 2.145989e-02 1.668 0 0
RSV-host interactions R-HSA-9833110 2.200237e-02 1.658 0 0
Erythropoietin activates RAS R-HSA-9027284 2.806734e-02 1.552 0 0
CLEC7A (Dectin-1) induces NFAT activation R-HSA-5607763 2.541333e-02 1.595 0 0
Generation of second messenger molecules R-HSA-202433 2.694991e-02 1.569 0 0
Clathrin-mediated endocytosis R-HSA-8856828 2.375745e-02 1.624 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.842860e-02 1.546 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 2.842860e-02 1.546 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 2.452065e-02 1.610 0 0
Interleukin-12 signaling R-HSA-9020591 2.860263e-02 1.544 0 0
RAF/MAP kinase cascade R-HSA-5673001 2.670214e-02 1.573 0 0
MAPK family signaling cascades R-HSA-5683057 2.986142e-02 1.525 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 2.551363e-02 1.593 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 2.990661e-02 1.524 0 0
SARS-CoV-2 Infection R-HSA-9694516 3.081718e-02 1.511 0 0
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-HSA-399955 3.082734e-02 1.511 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 3.084737e-02 1.511 0 0
Ca-dependent events R-HSA-111996 3.151280e-02 1.502 0 0
MTOR signalling R-HSA-165159 3.151280e-02 1.502 0 0
Sensory processing of sound R-HSA-9659379 3.191372e-02 1.496 0 0
Signaling by MET R-HSA-6806834 3.306534e-02 1.481 0 0
Cell-cell junction organization R-HSA-421270 3.328804e-02 1.478 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 3.368999e-02 1.472 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 3.368999e-02 1.472 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.476518e-02 1.459 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 3.665205e-02 1.436 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 3.665205e-02 1.436 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 3.665205e-02 1.436 0 0
Signaling by Hippo R-HSA-2028269 3.665205e-02 1.436 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 3.818438e-02 1.418 0 0
Ephrin signaling R-HSA-3928664 3.971035e-02 1.401 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 3.971035e-02 1.401 0 0
Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) R-HSA-5619050 3.998239e-02 1.398 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 3.998239e-02 1.398 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 3.998239e-02 1.398 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 3.998239e-02 1.398 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 3.998239e-02 1.398 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 4.176869e-02 1.379 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 4.286175e-02 1.368 0 0
Other interleukin signaling R-HSA-449836 4.286175e-02 1.368 0 0
Interleukin-12 family signaling R-HSA-447115 4.314653e-02 1.365 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 5.295300e-02 1.276 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 5.295300e-02 1.276 0 0
Defective AHCY causes HMAHCHD R-HSA-5578997 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 5.295300e-02 1.276 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 5.295300e-02 1.276 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 5.295300e-02 1.276 0 0
Axonal growth stimulation R-HSA-209563 6.574916e-02 1.182 0 0
MET activates PTPN11 R-HSA-8865999 6.574916e-02 1.182 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 4.943178e-02 1.306 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 4.943178e-02 1.306 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 5.284450e-02 1.277 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 5.284450e-02 1.277 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 5.284450e-02 1.277 0 0
FGFR2 alternative splicing R-HSA-6803529 5.633852e-02 1.249 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 5.633852e-02 1.249 0 0
Deadenylation of mRNA R-HSA-429947 6.355934e-02 1.197 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 5.633852e-02 1.249 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 6.519523e-02 1.186 0 0
Leishmania phagocytosis R-HSA-9664417 6.473774e-02 1.189 0 0
Parasite infection R-HSA-9664407 6.473774e-02 1.189 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 6.473774e-02 1.189 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 5.143833e-02 1.289 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 5.295300e-02 1.276 0 0
MET interacts with TNS proteins R-HSA-8875513 6.574916e-02 1.182 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 5.323535e-02 1.274 0 0
Attachment and Entry R-HSA-9694614 5.284450e-02 1.277 0 0
Diseases of Cellular Senescence R-HSA-9630747 5.295300e-02 1.276 0 0
Diseases of cellular response to stress R-HSA-9675132 5.295300e-02 1.276 0 0
Translation R-HSA-72766 4.533844e-02 1.344 0 0
Ion homeostasis R-HSA-5578775 5.771405e-02 1.239 0 0
Leishmania infection R-HSA-9658195 5.515789e-02 1.258 0 0
Parasitic Infection Pathways R-HSA-9824443 5.515789e-02 1.258 0 0
ESR-mediated signaling R-HSA-8939211 6.337024e-02 1.198 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 4.610323e-02 1.336 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 4.943178e-02 1.306 0 0
Growth hormone receptor signaling R-HSA-982772 5.991105e-02 1.222 0 0
Signal transduction by L1 R-HSA-445144 4.610323e-02 1.336 0 0
Estrogen-dependent gene expression R-HSA-9018519 5.934302e-02 1.227 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 6.116013e-02 1.214 0 0
SARS-CoV-1 Infection R-HSA-9678108 5.082154e-02 1.294 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 4.942455e-02 1.306 0 0
Signaling by ERBB2 R-HSA-1227986 6.661498e-02 1.176 1 0
Long-term potentiation R-HSA-9620244 6.728073e-02 1.172 0 0
Laminin interactions R-HSA-3000157 6.728073e-02 1.172 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 6.728073e-02 1.172 0 0
Sema4D in semaphorin signaling R-HSA-400685 6.728073e-02 1.172 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 6.895881e-02 1.161 0 0
MET activates PTK2 signaling R-HSA-8874081 7.107260e-02 1.148 0 0
Signaling by EGFR in Cancer R-HSA-1643713 7.107260e-02 1.148 0 0
Innate Immune System R-HSA-168249 7.180638e-02 1.144 0 0
Opioid Signalling R-HSA-111885 7.324167e-02 1.135 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 7.367693e-02 1.133 0 0
Synthesis of active ubiquitin: roles of E1 and E2 enzymes R-HSA-8866652 7.493237e-02 1.125 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 7.493237e-02 1.125 0 0
Regulation of gap junction activity R-HSA-191650 7.837320e-02 1.106 0 0
SARS-CoV-2 targets PDZ proteins in cell-cell junction R-HSA-9705677 7.837320e-02 1.106 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 7.837320e-02 1.106 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 7.885755e-02 1.103 0 0
Metabolism of proteins R-HSA-392499 8.254240e-02 1.083 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 8.284568e-02 1.082 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 8.284568e-02 1.082 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 8.689437e-02 1.061 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 8.689437e-02 1.061 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 8.689437e-02 1.061 0 0
Interleukin-37 signaling R-HSA-9008059 8.689437e-02 1.061 0 0
IRS activation R-HSA-74713 9.082742e-02 1.042 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 9.082742e-02 1.042 0 0
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production R-HSA-3134973 9.082742e-02 1.042 0 0
Co-inhibition by BTLA R-HSA-9927353 9.082742e-02 1.042 0 0
Molecules associated with elastic fibres R-HSA-2129379 9.100126e-02 1.041 0 0
Downstream signal transduction R-HSA-186763 9.100126e-02 1.041 0 0
Diseases of mitotic cell cycle R-HSA-9675126 9.516406e-02 1.022 0 0
HS-GAG degradation R-HSA-2024096 9.516406e-02 1.022 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 9.672431e-02 1.014 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 9.938054e-02 1.003 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 9.938054e-02 1.003 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 9.938054e-02 1.003 0 0
Signaling by FGFR in disease R-HSA-1226099 1.022013e-01 0.991 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 1.031141e-01 0.987 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 1.031141e-01 0.987 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.031141e-01 0.987 0 0
Cam-PDE 1 activation R-HSA-111957 1.031141e-01 0.987 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.031141e-01 0.987 0 0
Erythropoietin activates STAT5 R-HSA-9027283 1.152355e-01 0.938 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 1.271938e-01 0.896 0 0
TRIF-mediated programmed cell death R-HSA-2562578 1.271938e-01 0.896 0 0
SOS-mediated signalling R-HSA-112412 1.271938e-01 0.896 0 0
Recycling of eIF2:GDP R-HSA-72731 1.271938e-01 0.896 0 0
Type I hemidesmosome assembly R-HSA-446107 1.389912e-01 0.857 0 0
MET receptor recycling R-HSA-8875656 1.389912e-01 0.857 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 1.389912e-01 0.857 0 0
Lipophagy R-HSA-9613354 1.506299e-01 0.822 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 1.621119e-01 0.790 0 0
Activation of Ca-permeable Kainate Receptor R-HSA-451308 1.621119e-01 0.790 0 0
Folding of actin by CCT/TriC R-HSA-390450 1.621119e-01 0.790 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 1.846145e-01 0.734 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 2.065155e-01 0.685 0 0
Striated Muscle Contraction R-HSA-390522 1.036485e-01 0.984 0 0
Developmental Lineage of Mammary Gland Alveolar Cells R-HSA-9927426 1.079658e-01 0.967 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 1.676879e-01 0.775 0 0
Formation of RNA Pol II elongation complex R-HSA-112382 1.968448e-01 0.706 0 0
RNA Polymerase II Transcription Elongation R-HSA-75955 2.017663e-01 0.695 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.596853e-01 0.797 0 0
Formation of a pool of free 40S subunits R-HSA-72689 1.761863e-01 0.754 0 0
Post-translational protein phosphorylation R-HSA-8957275 1.863064e-01 0.730 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 1.172445e-01 0.931 0 0
HS-GAG biosynthesis R-HSA-2022928 1.167400e-01 0.933 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 1.079658e-01 0.967 0 0
Activation of RAC1 downstream of NMDARs R-HSA-9619229 1.506299e-01 0.822 0 0
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde R-HSA-442729 1.389912e-01 0.857 0 0
Regulation of CDH11 function R-HSA-9762292 1.621119e-01 0.790 0 0
PI3K/AKT activation R-HSA-198203 1.621119e-01 0.790 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 1.734395e-01 0.761 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 1.036485e-01 0.984 0 0
Peptide chain elongation R-HSA-156902 1.468504e-01 0.833 0 0
Microbial factors inhibit CASP4 activity R-HSA-9956593 2.065155e-01 0.685 0 0
Mitotic Spindle Checkpoint R-HSA-69618 1.931363e-01 0.714 0 0
Interleukin-6 signaling R-HSA-1059683 2.065155e-01 0.685 0 0
PTK6 Expression R-HSA-8849473 1.271938e-01 0.896 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 1.389912e-01 0.857 0 0
Calcineurin activates NFAT R-HSA-2025928 1.506299e-01 0.822 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 2.065155e-01 0.685 0 0
p75NTR regulates axonogenesis R-HSA-193697 1.506299e-01 0.822 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 1.621119e-01 0.790 0 0
Ionotropic activity of kainate receptors R-HSA-451306 1.734395e-01 0.761 0 0
vRNP Assembly R-HSA-192905 1.734395e-01 0.761 0 0
NF-kB is activated and signals survival R-HSA-209560 1.846145e-01 0.734 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.956392e-01 0.709 0 0
VLDLR internalisation and degradation R-HSA-8866427 1.956392e-01 0.709 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.065155e-01 0.685 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 2.065155e-01 0.685 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 1.167400e-01 0.933 0 0
eNOS activation R-HSA-203615 1.079658e-01 0.967 0 0
rRNA processing R-HSA-72312 1.313211e-01 0.882 0 0
p75NTR recruits signalling complexes R-HSA-209543 1.956392e-01 0.709 0 0
Signal attenuation R-HSA-74749 1.621119e-01 0.790 0 0
Interleukin-27 signaling R-HSA-9020956 1.621119e-01 0.790 0 0
Chylomicron assembly R-HSA-8963888 1.734395e-01 0.761 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 1.629037e-01 0.788 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 1.256870e-01 0.901 0 0
Signaling by FGFR1 in disease R-HSA-5655302 1.440382e-01 0.842 0 0
LDL remodeling R-HSA-8964041 1.271938e-01 0.896 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 1.389912e-01 0.857 0 0
Regulation of signaling by NODAL R-HSA-1433617 1.506299e-01 0.822 0 0
MAPK1 (ERK2) activation R-HSA-112411 1.506299e-01 0.822 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 1.621119e-01 0.790 0 0
Reduction of cytosolic Ca++ levels R-HSA-418359 1.846145e-01 0.734 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 2.065155e-01 0.685 0 0
Pexophagy R-HSA-9664873 1.621119e-01 0.790 0 0
CASP4 inflammasome assembly R-HSA-9948001 1.621119e-01 0.790 0 0
Cation-coupled Chloride cotransporters R-HSA-426117 1.271938e-01 0.896 0 0
MAPK3 (ERK1) activation R-HSA-110056 1.621119e-01 0.790 0 0
Bicarbonate transporters R-HSA-425381 1.734395e-01 0.761 0 0
Sodium/Calcium exchangers R-HSA-425561 1.846145e-01 0.734 0 0
Regulation of IFNG signaling R-HSA-877312 1.956392e-01 0.709 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 1.211929e-01 0.917 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 1.302205e-01 0.885 0 0
ISG15 antiviral mechanism R-HSA-1169408 1.049854e-01 0.979 0 0
GPVI-mediated activation cascade R-HSA-114604 1.167400e-01 0.933 0 0
Signaling by FGFR2 R-HSA-5654738 1.193412e-01 0.923 0 0
Regulation of CDH11 gene transcription R-HSA-9762293 1.506299e-01 0.822 0 0
RET signaling R-HSA-8853659 1.167400e-01 0.933 0 0
Signaling by FGFR R-HSA-190236 1.863064e-01 0.730 0 0
Nef and signal transduction R-HSA-164944 1.152355e-01 0.938 0 0
VLDL assembly R-HSA-8866423 1.152355e-01 0.938 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 1.956392e-01 0.709 0 0
Disorders of Nervous System Development R-HSA-9697154 1.956392e-01 0.709 0 0
Pervasive developmental disorders R-HSA-9005895 1.956392e-01 0.709 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 1.795423e-01 0.746 0 0
Elastic fibre formation R-HSA-1566948 1.256870e-01 0.901 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.506299e-01 0.822 0 0
Erythrocytes take up oxygen and release carbon dioxide R-HSA-1247673 1.956392e-01 0.709 0 0
NFE2L2 regulating tumorigenic genes R-HSA-9818030 2.065155e-01 0.685 0 0
PI3K Cascade R-HSA-109704 1.870494e-01 0.728 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 2.067019e-01 0.685 0 0
Oncogene Induced Senescence R-HSA-2559585 1.123303e-01 0.950 0 0
Interleukin-35 Signalling R-HSA-8984722 1.956392e-01 0.709 0 0
Frs2-mediated activation R-HSA-170968 2.065155e-01 0.685 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.506299e-01 0.822 0 0
Positive Regulation of CDH1 Gene Transcription R-HSA-9764790 1.621119e-01 0.790 0 0
Signaling by FGFR2 in disease R-HSA-5655253 1.870494e-01 0.728 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.995697e-01 0.700 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 1.965747e-01 0.706 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 2.065155e-01 0.685 0 0
Signaling by Leptin R-HSA-2586552 1.621119e-01 0.790 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.487106e-01 0.828 0 0
Somitogenesis R-HSA-9824272 1.629037e-01 0.788 0 0
SLC-mediated transport of inorganic anions R-HSA-9958790 1.256870e-01 0.901 0 0
Influenza Infection R-HSA-168255 1.348171e-01 0.870 0 0
RAF activation R-HSA-5673000 1.079658e-01 0.967 0 0
Signaling by NTRKs R-HSA-166520 1.913122e-01 0.718 0 0
Response of Mtb to phagocytosis R-HSA-9637690 1.534135e-01 0.814 0 0
Post-translational protein modification R-HSA-597592 2.067123e-01 0.685 0 0
Signaling by SCF-KIT R-HSA-1433557 1.534135e-01 0.814 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 1.534135e-01 0.814 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 2.069779e-01 0.684 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 2.107438e-01 0.676 0 0
Nucleotide Excision Repair R-HSA-5696398 2.139819e-01 0.670 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 2.166105e-01 0.664 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 2.166105e-01 0.664 0 0
Retrograde neurotrophin signalling R-HSA-177504 2.172454e-01 0.663 0 0
NRIF signals cell death from the nucleus R-HSA-205043 2.172454e-01 0.663 0 0
Signaling by FGFR4 in disease R-HSA-5655291 2.172454e-01 0.663 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 2.172454e-01 0.663 0 0
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation R-HSA-975163 2.172454e-01 0.663 0 0
CRMPs in Sema3A signaling R-HSA-399956 2.172454e-01 0.663 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 2.172454e-01 0.663 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 2.172454e-01 0.663 0 0
Regulation of KIT signaling R-HSA-1433559 2.172454e-01 0.663 0 0
Non-canonical inflammasome activation R-HSA-9686114 2.172454e-01 0.663 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 2.192389e-01 0.659 0 0
IRS-mediated signalling R-HSA-112399 2.215810e-01 0.654 0 0
Interferon gamma signaling R-HSA-877300 2.220911e-01 0.653 0 0
Signaling by TGFB family members R-HSA-9006936 2.249532e-01 0.648 0 0
Dual incision in TC-NER R-HSA-6782135 2.265608e-01 0.645 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 2.265608e-01 0.645 0 0
TRAF6-mediated induction of TAK1 complex within TLR4 complex R-HSA-937072 2.278308e-01 0.642 0 0
DCC mediated attractive signaling R-HSA-418885 2.278308e-01 0.642 0 0
p75NTR signals via NF-kB R-HSA-193639 2.278308e-01 0.642 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 2.278308e-01 0.642 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.278308e-01 0.642 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 2.278308e-01 0.642 0 0
Other semaphorin interactions R-HSA-416700 2.278308e-01 0.642 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 2.315486e-01 0.635 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 2.315486e-01 0.635 0 0
TCR signaling R-HSA-202403 2.317041e-01 0.635 0 0
Phosphorylation of the APC/C R-HSA-176412 2.382738e-01 0.623 0 0
Entry of Influenza Virion into Host Cell via Endocytosis R-HSA-168275 2.382738e-01 0.623 0 0
Aberrant regulation of mitotic exit in cancer due to RB1 defects R-HSA-9687136 2.382738e-01 0.623 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 2.382738e-01 0.623 0 0
Caspase activation via Death Receptors in the presence of ligand R-HSA-140534 2.382738e-01 0.623 0 0
Prolonged ERK activation events R-HSA-169893 2.382738e-01 0.623 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 2.388681e-01 0.622 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 2.388681e-01 0.622 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 2.415441e-01 0.617 0 0
Formation of paraxial mesoderm R-HSA-9793380 2.415441e-01 0.617 0 0
NCAM signaling for neurite out-growth R-HSA-375165 2.465495e-01 0.608 0 0
Signaling by PDGF R-HSA-186797 2.465495e-01 0.608 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 2.485761e-01 0.605 0 0
Fibronectin matrix formation R-HSA-1566977 2.485761e-01 0.605 0 0
Inactivation of APC/C via direct inhibition of the APC/C complex R-HSA-141430 2.485761e-01 0.605 0 0
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components R-HSA-141405 2.485761e-01 0.605 0 0
Disorders of Developmental Biology R-HSA-9675151 2.485761e-01 0.605 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 2.496834e-01 0.603 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 2.515587e-01 0.599 0 0
Signaling by PTK6 R-HSA-8848021 2.515587e-01 0.599 0 0
CD22 mediated BCR regulation R-HSA-5690714 2.565707e-01 0.591 0 0
Insulin receptor signalling cascade R-HSA-74751 2.565707e-01 0.591 0 0
IGF1R signaling cascade R-HSA-2428924 2.565707e-01 0.591 0 0
Ion transport by P-type ATPases R-HSA-936837 2.565707e-01 0.591 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 2.569346e-01 0.590 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 2.569346e-01 0.590 0 0
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase R-HSA-176407 2.587397e-01 0.587 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 2.587397e-01 0.587 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.587397e-01 0.587 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 2.615844e-01 0.582 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 2.615844e-01 0.582 0 0
Signaling by Nuclear Receptors R-HSA-9006931 2.674767e-01 0.573 0 0
GAB1 signalosome R-HSA-180292 2.687665e-01 0.571 0 0
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.687665e-01 0.571 0 0
PKA activation R-HSA-163615 2.687665e-01 0.571 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 2.687665e-01 0.571 0 0
Platelet sensitization by LDL R-HSA-432142 2.687665e-01 0.571 0 0
Cell surface interactions at the vascular wall R-HSA-202733 2.728728e-01 0.564 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 2.786583e-01 0.555 0 0
IKK complex recruitment mediated by RIP1 R-HSA-937041 2.786583e-01 0.555 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 2.786583e-01 0.555 0 0
Abortive elongation of HIV-1 transcript in the absence of Tat R-HSA-167242 2.786583e-01 0.555 0 0
Signaling by FGFR2 IIIa TM R-HSA-8851708 2.786583e-01 0.555 0 0
The NLRP3 inflammasome R-HSA-844456 2.786583e-01 0.555 0 0
Strand-asynchronous mitochondrial DNA replication R-HSA-9913635 2.786583e-01 0.555 0 0
O2/CO2 exchange in erythrocytes R-HSA-1480926 2.786583e-01 0.555 0 0
Regulation of signaling by CBL R-HSA-912631 2.786583e-01 0.555 0 0
Erythrocytes take up carbon dioxide and release oxygen R-HSA-1237044 2.786583e-01 0.555 0 0
STING mediated induction of host immune responses R-HSA-1834941 2.786583e-01 0.555 0 0
Chromosome Maintenance R-HSA-73886 2.788477e-01 0.555 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 2.788477e-01 0.555 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 2.816383e-01 0.550 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 2.861942e-01 0.543 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 2.866470e-01 0.543 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 2.884168e-01 0.540 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 2.884168e-01 0.540 0 0
Signaling by NODAL R-HSA-1181150 2.884168e-01 0.540 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 2.916521e-01 0.535 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.916521e-01 0.535 0 0
ECM proteoglycans R-HSA-3000178 2.916521e-01 0.535 0 0
Retinoid metabolism and transport R-HSA-975634 2.916521e-01 0.535 0 0
Metabolism of cofactors R-HSA-8978934 2.916521e-01 0.535 0 0
APC-Cdc20 mediated degradation of Nek2A R-HSA-179409 2.980439e-01 0.526 0 0
MyD88 deficiency (TLR2/4) R-HSA-5602498 2.980439e-01 0.526 0 0
PKA-mediated phosphorylation of CREB R-HSA-111931 2.980439e-01 0.526 0 0
Basigin interactions R-HSA-210991 2.980439e-01 0.526 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 3.009314e-01 0.522 0 0
Ca2+ pathway R-HSA-4086398 3.016483e-01 0.520 0 0
RNA Polymerase II Pre-transcription Events R-HSA-674695 3.066377e-01 0.513 0 0
Signaling by NOTCH4 R-HSA-9013694 3.066377e-01 0.513 0 0
IRAK4 deficiency (TLR2/4) R-HSA-5603041 3.075414e-01 0.512 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 3.075414e-01 0.512 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.075414e-01 0.512 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 3.075414e-01 0.512 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 3.083159e-01 0.511 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 3.116205e-01 0.506 0 0
Protein ubiquitination R-HSA-8852135 3.116205e-01 0.506 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 3.169110e-01 0.499 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 3.169110e-01 0.499 0 0
LDL clearance R-HSA-8964038 3.169110e-01 0.499 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 3.169110e-01 0.499 0 0
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain R-HSA-6804115 3.169110e-01 0.499 0 0
Cardiac conduction R-HSA-5576891 3.231022e-01 0.491 0 0
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection R-HSA-167160 3.261543e-01 0.487 0 0
RNA Pol II CTD phosphorylation and interaction with CE R-HSA-77075 3.261543e-01 0.487 0 0
Interleukin-20 family signaling R-HSA-8854691 3.261543e-01 0.487 0 0
Response of EIF2AK1 (HRI) to heme deficiency R-HSA-9648895 3.261543e-01 0.487 0 0
Interleukin receptor SHC signaling R-HSA-912526 3.261543e-01 0.487 0 0
Formation of the ureteric bud R-HSA-9830674 3.261543e-01 0.487 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 3.261543e-01 0.487 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.261543e-01 0.487 0 0
Integrin cell surface interactions R-HSA-216083 3.265213e-01 0.486 0 0
Bacterial Infection Pathways R-HSA-9824439 3.272376e-01 0.485 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 3.352731e-01 0.475 0 0
Interleukin-6 family signaling R-HSA-6783589 3.352731e-01 0.475 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 3.352731e-01 0.475 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 3.352731e-01 0.475 0 0
Plasma lipoprotein assembly R-HSA-8963898 3.352731e-01 0.475 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 3.364087e-01 0.473 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 3.364087e-01 0.473 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 3.413366e-01 0.467 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 3.442691e-01 0.463 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 3.442691e-01 0.463 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 3.442691e-01 0.463 0 0
TGFBR3 expression R-HSA-9839394 3.442691e-01 0.463 0 0
Glycogen breakdown (glycogenolysis) R-HSA-70221 3.442691e-01 0.463 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 3.442691e-01 0.463 0 0
Interleukin-7 signaling R-HSA-1266695 3.442691e-01 0.463 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 3.452825e-01 0.462 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 3.462531e-01 0.461 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 3.531439e-01 0.452 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 3.531439e-01 0.452 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 3.531439e-01 0.452 0 0
Cellular response to chemical stress R-HSA-9711123 3.547578e-01 0.450 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 3.560495e-01 0.448 0 0
Unfolded Protein Response (UPR) R-HSA-381119 3.563537e-01 0.448 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 3.618991e-01 0.441 0 0
Tat-mediated HIV elongation arrest and recovery R-HSA-167243 3.618991e-01 0.441 0 0
Pausing and recovery of Tat-mediated HIV elongation R-HSA-167238 3.618991e-01 0.441 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 3.618991e-01 0.441 0 0
Signaling by FGFR3 in disease R-HSA-5655332 3.618991e-01 0.441 0 0
Insulin processing R-HSA-264876 3.618991e-01 0.441 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 3.618991e-01 0.441 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 3.657935e-01 0.437 0 0
Amplification of signal from the kinetochores R-HSA-141424 3.657935e-01 0.437 0 0
Intracellular signaling by second messengers R-HSA-9006925 3.704013e-01 0.431 0 0
Formation of the HIV-1 Early Elongation Complex R-HSA-167158 3.705363e-01 0.431 0 0
Formation of the Early Elongation Complex R-HSA-113418 3.705363e-01 0.431 0 0
HIV elongation arrest and recovery R-HSA-167287 3.705363e-01 0.431 0 0
Pausing and recovery of HIV elongation R-HSA-167290 3.705363e-01 0.431 0 0
Telomere Extension By Telomerase R-HSA-171319 3.705363e-01 0.431 0 0
Activation of kainate receptors upon glutamate binding R-HSA-451326 3.705363e-01 0.431 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 3.705363e-01 0.431 0 0
Inflammasomes R-HSA-622312 3.705363e-01 0.431 0 0
Iron assimilation using enterobactin R-HSA-9638334 3.705363e-01 0.431 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 3.706445e-01 0.431 0 0
XBP1(S) activates chaperone genes R-HSA-381038 3.706445e-01 0.431 0 0
Late endosomal microautophagy R-HSA-9615710 3.790572e-01 0.421 0 0
mRNA Capping R-HSA-72086 3.790572e-01 0.421 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 3.790572e-01 0.421 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 3.790572e-01 0.421 0 0
DARPP-32 events R-HSA-180024 3.790572e-01 0.421 0 0
Platelet calcium homeostasis R-HSA-418360 3.790572e-01 0.421 0 0
ER-Phagosome pathway R-HSA-1236974 3.851075e-01 0.414 0 0
DAP12 signaling R-HSA-2424491 3.874632e-01 0.412 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 3.874632e-01 0.412 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 3.874632e-01 0.412 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.874632e-01 0.412 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.874632e-01 0.412 1 1
Visual phototransduction R-HSA-2187338 3.893914e-01 0.410 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 3.946699e-01 0.404 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 3.946699e-01 0.404 0 0
Trafficking of AMPA receptors R-HSA-399719 3.957560e-01 0.403 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 3.957560e-01 0.403 0 0
IRE1alpha activates chaperones R-HSA-381070 3.994258e-01 0.399 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 4.003198e-01 0.398 0 0
Signaling by Insulin receptor R-HSA-74752 4.041644e-01 0.393 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 4.041644e-01 0.393 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 4.075759e-01 0.390 0 0
Interleukin-1 family signaling R-HSA-446652 4.075759e-01 0.390 0 0
FGFR1 mutant receptor activation R-HSA-1839124 4.120077e-01 0.385 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 4.120077e-01 0.385 0 0
Regulation of necroptotic cell death R-HSA-5675482 4.120077e-01 0.385 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 4.120077e-01 0.385 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.135879e-01 0.383 0 0
Collagen formation R-HSA-1474290 4.135879e-01 0.383 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 4.182720e-01 0.379 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 4.182720e-01 0.379 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 4.199696e-01 0.377 0 0
Effects of PIP2 hydrolysis R-HSA-114508 4.199696e-01 0.377 0 0
Eukaryotic Translation Termination R-HSA-72764 4.229373e-01 0.374 0 0
Dual Incision in GG-NER R-HSA-5696400 4.278242e-01 0.369 0 0
Nuclear import of Rev protein R-HSA-180746 4.278242e-01 0.369 0 0
Regulation of TLR by endogenous ligand R-HSA-5686938 4.278242e-01 0.369 0 0
Antigen Presentation: Folding, assembly and peptide loading of class I MHC R-HSA-983170 4.278242e-01 0.369 0 0
Calnexin/calreticulin cycle R-HSA-901042 4.278242e-01 0.369 0 0
Mitophagy R-HSA-5205647 4.278242e-01 0.369 0 0
Hyaluronan metabolism R-HSA-2142845 4.278242e-01 0.369 0 0
Cellular response to starvation R-HSA-9711097 4.291808e-01 0.367 0 0
Telomere Maintenance R-HSA-157579 4.322097e-01 0.364 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 4.355729e-01 0.361 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 4.355729e-01 0.361 0 0
PERK regulates gene expression R-HSA-381042 4.355729e-01 0.361 0 0
Metabolism of ingested SeMet, Sec, MeSec into H2Se R-HSA-2408508 4.355729e-01 0.361 0 0
Signalling to ERKs R-HSA-187687 4.355729e-01 0.361 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 4.414026e-01 0.355 0 0
FLT3 signaling in disease R-HSA-9682385 4.432172e-01 0.353 0 0
FGFR2 mutant receptor activation R-HSA-1839126 4.432172e-01 0.353 0 0
ABC-family proteins mediated transport R-HSA-382556 4.459685e-01 0.351 0 0
Selenoamino acid metabolism R-HSA-2408522 4.505029e-01 0.346 0 0
Selenocysteine synthesis R-HSA-2408557 4.505136e-01 0.346 0 0
Voltage gated Potassium channels R-HSA-1296072 4.507584e-01 0.346 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 4.581979e-01 0.339 0 0
Viral mRNA Translation R-HSA-192823 4.595404e-01 0.338 0 0
Formation of HIV-1 elongation complex containing HIV-1 Tat R-HSA-167200 4.655371e-01 0.332 0 0
RAS processing R-HSA-9648002 4.655371e-01 0.332 0 0
Plasma lipoprotein clearance R-HSA-8964043 4.655371e-01 0.332 0 0
Signaling by ALK R-HSA-201556 4.655371e-01 0.332 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 4.711928e-01 0.327 0 0
Formation of HIV elongation complex in the absence of HIV Tat R-HSA-167152 4.727773e-01 0.325 0 0
HIV Transcription Elongation R-HSA-167169 4.727773e-01 0.325 0 0
Tat-mediated elongation of the HIV-1 transcript R-HSA-167246 4.727773e-01 0.325 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 4.727773e-01 0.325 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 4.727773e-01 0.325 0 0
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-73779 4.727773e-01 0.325 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 4.727773e-01 0.325 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 4.727773e-01 0.325 0 0
Diseases of Immune System R-HSA-5260271 4.727773e-01 0.325 0 0
Diseases associated with the TLR signaling cascade R-HSA-5602358 4.727773e-01 0.325 0 0
Glycogen metabolism R-HSA-8982491 4.727773e-01 0.325 0 0
Interleukin-2 family signaling R-HSA-451927 4.727773e-01 0.325 0 0
Platelet homeostasis R-HSA-418346 4.773334e-01 0.321 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 4.784170e-01 0.320 0 0
Purine ribonucleoside monophosphate biosynthesis R-HSA-73817 4.799199e-01 0.319 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 4.799199e-01 0.319 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 4.817261e-01 0.317 0 0
Gene Silencing by RNA R-HSA-211000 4.817261e-01 0.317 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 4.852938e-01 0.314 0 0
Leishmania parasite growth and survival R-HSA-9664433 4.852938e-01 0.314 0 0
Antigen processing-Cross presentation R-HSA-1236975 4.860961e-01 0.313 0 0
RNA Polymerase II HIV Promoter Escape R-HSA-167162 4.869662e-01 0.313 0 0
HIV Transcription Initiation R-HSA-167161 4.869662e-01 0.313 0 0
RNA Polymerase II Transcription Initiation R-HSA-75953 4.869662e-01 0.313 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 4.939174e-01 0.306 0 0
RNA Polymerase II Promoter Escape R-HSA-73776 5.007749e-01 0.300 0 0
Signaling by FGFR4 R-HSA-5654743 5.007749e-01 0.300 0 0
G1 Phase R-HSA-69236 5.075398e-01 0.295 0 0
Cyclin D associated events in G1 R-HSA-69231 5.075398e-01 0.295 0 0
Netrin-1 signaling R-HSA-373752 5.075398e-01 0.295 0 0
DAP12 interactions R-HSA-2172127 5.075398e-01 0.295 0 0
Surfactant metabolism R-HSA-5683826 5.075398e-01 0.295 0 0
Methylation R-HSA-156581 5.075398e-01 0.295 0 0
Cellular Senescence R-HSA-2559583 5.090138e-01 0.293 0 0
RNA Polymerase II Transcription Initiation And Promoter Clearance R-HSA-76042 5.142136e-01 0.289 0 0
Nucleosome assembly R-HSA-774815 5.142136e-01 0.289 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 5.142136e-01 0.289 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 5.142136e-01 0.289 0 0
Signaling by FGFR3 R-HSA-5654741 5.142136e-01 0.289 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 5.207972e-01 0.283 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 5.207972e-01 0.283 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 5.207972e-01 0.283 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 5.207972e-01 0.283 0 0
Signaling by TGFBR3 R-HSA-9839373 5.207972e-01 0.283 0 0
Cell Cycle Checkpoints R-HSA-69620 5.239734e-01 0.281 0 0
Interferon alpha/beta signaling R-HSA-909733 5.243774e-01 0.280 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 5.272921e-01 0.278 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 5.336993e-01 0.273 0 0
GPER1 signaling R-HSA-9634597 5.336993e-01 0.273 0 0
Metal ion SLC transporters R-HSA-425410 5.336993e-01 0.273 0 0
Plasma lipoprotein remodeling R-HSA-8963899 5.336993e-01 0.273 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 5.367073e-01 0.270 0 0
Degradation of CDH1 R-HSA-9766229 5.400201e-01 0.268 0 0
N-glycan trimming in the ER and Calnexin/Calreticulin cycle R-HSA-532668 5.400201e-01 0.268 0 0
DNA Damage Bypass R-HSA-73893 5.400201e-01 0.268 0 0
Azathioprine ADME R-HSA-9748787 5.462555e-01 0.263 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 5.488169e-01 0.261 0 0
Glycosaminoglycan metabolism R-HSA-1630316 5.514988e-01 0.258 0 0
Hedgehog ligand biogenesis R-HSA-5358346 5.524069e-01 0.258 0 0
The phototransduction cascade R-HSA-2514856 5.524069e-01 0.258 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 5.567664e-01 0.254 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 5.584752e-01 0.253 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 5.584752e-01 0.253 0 0
Formation of the cornified envelope R-HSA-6809371 5.607040e-01 0.251 0 0
Host Interactions of HIV factors R-HSA-162909 5.607040e-01 0.251 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 5.644616e-01 0.248 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 5.644616e-01 0.248 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 5.644616e-01 0.248 0 0
Meiotic synapsis R-HSA-1221632 5.644616e-01 0.248 0 0
Nucleotide biosynthesis R-HSA-8956320 5.644616e-01 0.248 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 5.703672e-01 0.244 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 5.761931e-01 0.239 0 0
HDACs deacetylate histones R-HSA-3214815 5.761931e-01 0.239 0 0
G alpha (z) signalling events R-HSA-418597 5.761931e-01 0.239 0 0
Paracetamol ADME R-HSA-9753281 5.761931e-01 0.239 0 0
Signaling by NOTCH3 R-HSA-9012852 5.761931e-01 0.239 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 5.819403e-01 0.235 0 0
Signaling by EGFR R-HSA-177929 5.819403e-01 0.235 0 0
Signaling by FGFR1 R-HSA-5654736 5.819403e-01 0.235 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 5.819403e-01 0.235 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 5.826706e-01 0.235 0 0
Signaling by ROBO receptors R-HSA-376176 5.826706e-01 0.235 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 5.875669e-01 0.231 0 0
Nuclear Envelope Breakdown R-HSA-2980766 5.876100e-01 0.231 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 5.876100e-01 0.231 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 5.891779e-01 0.230 0 0
Extension of Telomeres R-HSA-180786 5.987207e-01 0.223 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 5.987207e-01 0.223 0 0
Metabolism of non-coding RNA R-HSA-194441 5.987207e-01 0.223 0 0
snRNP Assembly R-HSA-191859 5.987207e-01 0.223 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 5.987207e-01 0.223 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 6.041638e-01 0.219 0 0
Viral Messenger RNA Synthesis R-HSA-168325 6.095334e-01 0.215 0 0
Mitochondrial protein import R-HSA-1268020 6.148305e-01 0.211 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 6.148305e-01 0.211 0 0
Heme signaling R-HSA-9707616 6.148305e-01 0.211 0 0
Activation of gene expression by SREBF (SREBP) R-HSA-2426168 6.200560e-01 0.208 0 0
Ribosome-associated quality control R-HSA-9948299 6.238081e-01 0.205 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 6.252110e-01 0.204 0 0
DNA Double Strand Break Response R-HSA-5693606 6.402619e-01 0.194 0 0
Kidney development R-HSA-9830369 6.402619e-01 0.194 0 0
Transcription of the HIV genome R-HSA-167172 6.451439e-01 0.190 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 6.451439e-01 0.190 0 0
Regulated Necrosis R-HSA-5218859 6.451439e-01 0.190 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 6.516895e-01 0.186 0 0
HIV Infection R-HSA-162906 6.543820e-01 0.184 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 6.547110e-01 0.184 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 6.547110e-01 0.184 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 6.593978e-01 0.181 0 0
Regulation of mitotic cell cycle R-HSA-453276 6.593978e-01 0.181 0 0
Metal ion assimilation from the host R-HSA-9638482 6.593978e-01 0.181 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 6.597225e-01 0.181 0 0
Gastrulation R-HSA-9758941 6.640009e-01 0.178 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 6.640213e-01 0.178 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 6.685823e-01 0.175 0 0
Switching of origins to a post-replicative state R-HSA-69052 6.685823e-01 0.175 0 0
G2/M DNA damage checkpoint R-HSA-69473 6.730817e-01 0.172 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 6.734956e-01 0.172 0 0
DNA Replication R-HSA-69306 6.766120e-01 0.170 0 0
Death Receptor Signaling R-HSA-73887 6.797042e-01 0.168 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 6.818988e-01 0.166 0 0
UCH proteinases R-HSA-5689603 6.818988e-01 0.166 0 0
PPARA activates gene expression R-HSA-1989781 6.827724e-01 0.166 0 0
Signaling by NOTCH R-HSA-157118 6.880337e-01 0.162 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 6.888370e-01 0.162 0 0
Interleukin-10 signaling R-HSA-6783783 6.904792e-01 0.161 0 0
RNA Polymerase I Transcription R-HSA-73864 6.904792e-01 0.161 0 0
TP53 Regulates Transcription of DNA Repair Genes R-HSA-6796648 6.904792e-01 0.161 0 0
PCP/CE pathway R-HSA-4086400 6.904792e-01 0.161 0 0
G alpha (i) signalling events R-HSA-418594 6.937185e-01 0.159 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 6.946826e-01 0.158 0 0
Metabolic disorders of biological oxidation enzymes R-HSA-5579029 6.946826e-01 0.158 0 0
Processing of DNA double-strand break ends R-HSA-5693607 7.029197e-01 0.153 0 0
Transcriptional activation of mitochondrial biogenesis R-HSA-2151201 7.029197e-01 0.153 0 0
Meiosis R-HSA-1500620 7.187361e-01 0.143 0 0
Sulfur amino acid metabolism R-HSA-1614635 7.263270e-01 0.139 0 0
Neurotransmitter release cycle R-HSA-112310 7.409025e-01 0.130 0 0
Downstream TCR signaling R-HSA-202424 7.409025e-01 0.130 0 0
FCGR activation R-HSA-2029481 7.547051e-01 0.122 0 0
Assembly of the pre-replicative complex R-HSA-68867 7.547051e-01 0.122 0 0
Mitochondrial protein degradation R-HSA-9837999 7.580398e-01 0.120 0 0
DNA Repair R-HSA-73894 7.611544e-01 0.119 0 0
Diseases of glycosylation R-HSA-3781865 7.641081e-01 0.117 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 7.677755e-01 0.115 0 0
Potassium Channels R-HSA-1296071 7.677755e-01 0.115 0 0
Metabolism of vitamins and cofactors R-HSA-196854 7.682431e-01 0.115 0 0
Regulation of insulin secretion R-HSA-422356 7.740484e-01 0.111 0 0
Ion channel transport R-HSA-983712 7.757621e-01 0.110 0 0
HATs acetylate histones R-HSA-3214847 7.771213e-01 0.110 0 0
Interleukin-1 signaling R-HSA-9020702 7.831428e-01 0.106 0 0
Regulation of endogenous retroelements R-HSA-9842860 7.860926e-01 0.105 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 7.860926e-01 0.105 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 7.918728e-01 0.101 0 0
Activation of HOX genes during differentiation R-HSA-5619507 7.947043e-01 0.100 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 7.947043e-01 0.100 0 0
Co-inhibition by PD-1 R-HSA-389948 7.996484e-01 0.097 0 0
Synthesis of DNA R-HSA-69239 8.029709e-01 0.095 0 0
Stimuli-sensing channels R-HSA-2672351 8.056521e-01 0.094 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 8.056521e-01 0.094 0 0
Infection with Enterobacteria R-HSA-9640148 8.057613e-01 0.094 0 0
DNA Replication Pre-Initiation R-HSA-69002 8.082970e-01 0.092 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 8.082970e-01 0.092 0 0
Signaling by WNT R-HSA-195721 8.085955e-01 0.092 0 0
MyD88-independent TLR4 cascade R-HSA-166166 8.109060e-01 0.091 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 8.109060e-01 0.091 0 0
Keratinization R-HSA-6805567 8.136547e-01 0.090 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.160186e-01 0.088 0 0
Inositol phosphate metabolism R-HSA-1483249 8.160186e-01 0.088 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 8.185230e-01 0.087 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 8.209935e-01 0.086 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 8.258345e-01 0.083 0 0
Peptide hormone metabolism R-HSA-2980736 8.328527e-01 0.079 0 0
Mitochondrial biogenesis R-HSA-1592230 8.328527e-01 0.079 0 0
Homology Directed Repair R-HSA-5693538 8.351290e-01 0.078 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 8.373744e-01 0.077 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 8.373744e-01 0.077 0 0
Mitotic Prophase R-HSA-68875 8.395893e-01 0.076 0 0
Neddylation R-HSA-8951664 8.407688e-01 0.075 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 8.439296e-01 0.074 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 8.439296e-01 0.074 0 0
Epigenetic regulation of gene expression R-HSA-212165 8.470533e-01 0.072 0 0
G2/M Checkpoints R-HSA-69481 8.562613e-01 0.067 0 0
Chromatin modifying enzymes R-HSA-3247509 8.613330e-01 0.065 0 0
Reproduction R-HSA-1474165 8.639386e-01 0.064 0 0
Adipogenesis R-HSA-9843745 8.657932e-01 0.063 0 0
Integration of energy metabolism R-HSA-163685 8.764044e-01 0.057 0 0
Chromatin organization R-HSA-4839726 8.820347e-01 0.055 0 0
Late Phase of HIV Life Cycle R-HSA-162599 8.877329e-01 0.052 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 8.906882e-01 0.050 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 8.937358e-01 0.049 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 8.966164e-01 0.047 0 0
S Phase R-HSA-69242 8.966164e-01 0.047 0 0
MITF-M-dependent gene expression R-HSA-9856651 8.994192e-01 0.046 0 0
G alpha (q) signalling events R-HSA-416476 8.998576e-01 0.046 0 0
DNA Double-Strand Break Repair R-HSA-5693532 9.034822e-01 0.044 0 0
Protein localization R-HSA-9609507 9.034822e-01 0.044 0 0
HIV Life Cycle R-HSA-162587 9.086464e-01 0.042 0 0
SLC transporter disorders R-HSA-5619102 9.203852e-01 0.036 0 0
SLC-mediated transmembrane transport R-HSA-425407 9.250262e-01 0.034 0 0
G alpha (s) signalling events R-HSA-418555 9.256786e-01 0.034 0 0
PIP3 activates AKT signaling R-HSA-1257604 9.290452e-01 0.032 0 0
Peptide ligand-binding receptors R-HSA-375276 9.395469e-01 0.027 0 0
Toll-like Receptor Cascades R-HSA-168898 9.435712e-01 0.025 0 0
Diseases of metabolism R-HSA-5668914 9.444315e-01 0.025 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 9.589078e-01 0.018 0 0
GPCR downstream signalling R-HSA-388396 9.615858e-01 0.017 0 0
Drug ADME R-HSA-9748784 9.616479e-01 0.017 0 0
Transport of small molecules R-HSA-382551 9.655352e-01 0.015 0 0
Metabolism of nucleotides R-HSA-15869 9.700899e-01 0.013 0 0
Phase II - Conjugation of compounds R-HSA-156580 9.713047e-01 0.013 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.743093e-01 0.011 0 0
Deubiquitination R-HSA-5688426 9.770007e-01 0.010 0 0
Gene expression (Transcription) R-HSA-74160 9.800146e-01 0.009 0 0
Signaling by GPCR R-HSA-372790 9.813413e-01 0.008 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.832734e-01 0.007 0 0
Generic Transcription Pathway R-HSA-212436 9.840052e-01 0.007 0 0
RNA Polymerase II Transcription R-HSA-73857 9.888436e-01 0.005 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 9.904889e-01 0.004 0 0
Metabolism of steroids R-HSA-8957322 9.911654e-01 0.004 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.928413e-01 0.003 0 0
Biological oxidations R-HSA-211859 9.953359e-01 0.002 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.967137e-01 0.001 0 0
Sensory Perception R-HSA-9709957 9.985962e-01 0.001 0 0
GPCR ligand binding R-HSA-500792 9.997876e-01 0.000 0 0
Metabolism R-HSA-1430728 1.000000e+00 0.000 0 0
Metabolism of lipids R-HSA-556833 1.000000e+00 0.000 0 0
Top15 pathways (red highlights are reference pathways)

Compared with reference pathways