MARK4
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
Y Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: Y Sites / Y Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
Download
| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A4FU28 | S140 | Sugiyama | CTAGE9 | AAAEEARSLEATCEKLSRsNsELEDEILCLEKDLKEEKSKH |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| A8MPP1 | S279 | Sugiyama | DDX11L8 | LVSLGSRQNLCVNEDVRSLGsVQLINDRCVDMQRSRHEKKK |
| O00165 | S192 | Sugiyama | HAX1 HS1BP1 | VWPMDPHPRtREDNDLDsQVsQEGLGPVLQPQPKSYFKsIS |
| O00410 | S726 | Sugiyama | IPO5 KPNB3 RANBP5 | LMVPLLKFYFHDGVRVAAAEsMPLLLECARVRGPEYLTQMW |
| O00468 | S738 | Sugiyama | AGRN AGRIN | CGSDGVTYSTECELKKARCEsQRGLYVAAQGACRGPTFAPL |
| O00541 | S280 | Sugiyama | PES1 | AGEGTyALDSESCMEKLAALsAsLARVVVPATEEEAEVDEF |
| O14639 | S452 | Sugiyama | ABLIM1 ABLIM KIAA0059 LIMAB1 | PtPsAEGyQDVRDRMIHRstsQGsINsPVySRHsYtPTTSR |
| O14974 | S445 | Sugiyama | PPP1R12A MBS MYPT1 | EEERKDEsPATWRLGLRKtGsyGALAEItASKEGQKEKDTA |
| O14974 | S910 | Sugiyama | PPP1R12A MBS MYPT1 | yETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDST |
| O14980 | S1031 | Sugiyama | XPO1 CRM1 | FKEHLRDFLVQIKEFAGEDtsDLFLEEREIALRQADEEKHK |
| O14980 | S1055 | Sugiyama | XPO1 CRM1 | LEEREIALRQADEEKHKRQMsVPGIFNPHEIPEEMCD____ |
| O15013 | S1283 | Sugiyama | ARHGEF10 KIAA0294 | DAAIWLGDSLGSMTQKsDLssssGsLsLsHGsssLEHRSED |
| O15013 | S1284 | Sugiyama | ARHGEF10 KIAA0294 | AAIWLGDSLGSMTQKsDLssssGsLsLsHGsssLEHRSEDs |
| O15067 | S215 | Sugiyama | PFAS KIAA0361 | LDSWDLDFYTKRFQELQRNPstVEAFDLAQsNsEHSRHWFF |
| O15067 | T539 | Sugiyama | PFAS KIAA0361 | AGGNGNVLKELsDPAGAIIytsRFQLGDPTLNALEIWGAEY |
| O15460 | S531 | Sugiyama | P4HA2 UNQ290/PRO330 | KWVSNKWFHERGQEFLRPCGstEVD________________ |
| O43290 | S624 | Sugiyama | SART1 | IGWSTVNLDEEKQQQDFSASsTtILDEEPIVNRGLAAALLL |
| O43399 | S96 | Sugiyama | TPD52L2 | ELKRRLGLstLGELKQNLsRsWHDVQVssAyVKTSEKLGEW |
| O43707 | S763 | Sugiyama | ACTN4 | IARTINEVENQILtRDAKGIsQEQMQEFRASFNHFDKDHGG |
| O43765 | S197 | Sugiyama | SGTA SGT SGT1 | EAVAYYKKALELDPDNEtyKsNLKIAELKLREAPSPTGGVG |
| O43815 | S227 | Sugiyama | STRN | NGTEAEVKETAMIAKSELtDsAsVLDNFKFLEsAAADFsDE |
| O43823 | S323 | Sugiyama | AKAP8 AKAP95 | RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE |
| O43852 | S44 | Sugiyama | CALU | KKDRVHHEPQLsDKVHNDAQsFDyDHDAFLGAEEAKtFDQL |
| O43852 | S69 | Sugiyama | CALU | HDAFLGAEEAKtFDQLtPEEsKERLGKIVSKIDGDKDGFVt |
| O60216 | S580 | Sugiyama | RAD21 HR21 KIAA0078 NXP1 SCC1 | TQQMLHGLQRALAKTGAESIsLLELCRNTNRKQAAAKFYSF |
| O60291 | S515 | Sugiyama | MGRN1 KIAA0544 RNF156 | sFItEEVDESssPQQGTRAAsIENVLQDssPEHCGRGPPAD |
| O60333 | S1057 | Sugiyama | KIF1B KIAA0591 KIAA1448 | DNEYFNQSDFSSVAMTRsGLsLEELRIVEGQGQSSEVItPP |
| O60341 | S126 | Sugiyama | KDM1A AOF2 KDM1 KIAA0601 LSD1 | EGRRTsRRKRAKVEyREMDEsLANLsEDEyysEEERNAKAE |
| O60343 | S588 | Sugiyama | TBC1D4 AS160 KIAA0603 | tssLENIFSRGANRMRGRLGsVDsFERsNsLASEKDYsPGD |
| O60361 | Y136 | Sugiyama | NME2P1 | SLRFKPEELVDYKSCAHDWVyE___________________ |
| O60645 | S89 | Sugiyama | EXOC3 SEC6 SEC6L1 | LNDVKDIQQSLADVSKDWRQsINTIESLKDVKDAVVQHSQL |
| O60664 | S179 | Sugiyama | PLIN3 M6PRBP1 TIP47 | QSGVDKTKsVVtGGVQsVMGsRLGQMVLsGVDtVLGKsEEW |
| O60716 | S230 | Sugiyama | CTNND1 KIAA0384 | PDGysRHyEDGyPGGsDNyGsLsRVtRIEERyRPsMEGyRA |
| O60716 | S252 | Sugiyama | CTNND1 KIAA0384 | sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL |
| O60749 | S119 | Sugiyama | SNX2 TRG9 | AVtPVtPttLIAPRIESKsMsAPVIFDRsREEIEEEANGDI |
| O60763 | S805 | Sugiyama | USO1 VDP | EQVAELKQELATLKSQLNSQsVEITKLQTEKQELLQKTEAF |
| O60763 | S881 | Sugiyama | USO1 VDP | KNEIKALSEERTAIKEQLDssNsTIAILQTEKDKLELEITD |
| O60841 | S186 | Sugiyama | EIF5B IF2 KIAA0741 | EDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKKNQKN |
| O75122 | S327 | Sugiyama | CLASP2 KIAA0627 | YLKssGsVAsLPQsDRsssssQEsLNRPFSSKWSTANPSTV |
| O75179 | S243 | Sugiyama | ANKRD17 GTAR KIAA0697 | RAEStANAGQSDNRSLAEACsEGDVNAVRKLLIEGRSVNEH |
| O75436 | T102 | Sugiyama | VPS26A VPS26 | KSNTHEFVNLVKELALPGELtQSRSYDFEFMQVEKPYESYI |
| O75534 | T582 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | VEYSLSKGKGNKVSAEKVNKtHsVNGItEEADPTIysGKVI |
| O75534 | T589 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | GKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRPLRSVD |
| O75822 | S127 | Sugiyama | EIF3J EIF3S1 PRO0391 | VLtPEEQLADKLRLKKLQEEsDLELAKEtFGVNNAVyGIDA |
| O75822 | S202 | Sugiyama | EIF3J EIF3S1 PRO0391 | VLVRDVCISLEIDDLKKITNsLTVLCsEKQKQEKQSKAKKK |
| O76021 | S361 | Sugiyama | RSL1D1 CATX11 CSIG PBK1 L12 | PEHGKKKRGRGKAQVKAtNEsEDEIPQLVPIGKKtPANEKV |
| O94776 | S54 | Sugiyama | MTA2 MTA1L1 PID | ANGNVEAKVVCLFRRRDIsssLNSLADSNAREFEEESKQPG |
| O94874 | S777 | Sugiyama | UFL1 KIAA0776 MAXER NLBP RCAD | LDKEQEDVASTTRKELQELSssIKDLVLKSRKSsVTEE___ |
| O95155 | S105 | Sugiyama | UBE4B HDNB1 KIAA0684 UFD2 | LsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsMsQVDVDsG |
| O95218 | S165 | Sugiyama | ZRANB2 ZIS ZNF265 | LKEVEDKEsEGEEEDEDEDLsKyKLDEDEDEDDADLsKyNL |
| O95218 | S181 | Sugiyama | ZRANB2 ZIS ZNF265 | DEDLsKyKLDEDEDEDDADLsKyNLDAsEEEDsNKKKSNRR |
| O95218 | S75 | Sugiyama | ZRANB2 ZIS ZNF265 | tLAEKSRGLFsANDWQCKTCsNVNWARRsECNMCNtPKYAK |
| O95376 | S113 | Sugiyama | ARIH2 ARI2 TRIAD1 HT005 | LILVNFHWQVSEILDRYKSNsAQLLVEARVQPNPSKHVPTS |
| O95671 | T234 | Sugiyama | ASMTL | PPRPEDLRRsVKHDsIPAADtFEDLsDVEGGGsEPTQRDAG |
| O95757 | S599 | Sugiyama | HSPA4L APG1 HSPH3 OSP94 | sIDLPIQssLCRQLGQDLLNsyIENEGKMIMQDKLEKERND |
| O95816 | S31 | Sugiyama | BAG2 | NEGRFCRsssMADRsSRLLEsLDQLELRVEALREAATAVEQ |
| O95819 | S800 | Sugiyama | MAP4K4 HGK KIAA0687 NIK | DVEQEGADESTSGPEDTRAAsSLNLSNGETESVKTMIVHDD |
| P00338 | S105 | Sugiyama | LDHA PIG19 | VTANsKLVIItAGARQQEGEsRLNLVQRNVNIFKFIIPNVV |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00338 | T322 | Sugiyama | LDHA PIG19 | DLVKVTLtsEEEARLKKsADtLWGIQKELQF__________ |
| P00491 | S176 | Sugiyama | PNP NP | GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA |
| P00558 | S174 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | LSKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKEL |
| P00558 | S175 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | SKLGDVyVNDAFGtAHRAHssMVGVNLPQKAGGFLMKKELN |
| P00558 | S390 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | IIGGGDtAtCCAKWNtEDKVsHVstGGGAsLELLEGKVLPG |
| P00558 | S399 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | CCAKWNtEDKVsHVstGGGAsLELLEGKVLPGVDALsNI__ |
| P00558 | Y161 | Sugiyama | PGK1 PGKA MIG10 OK/SW-cl.110 | KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL |
| P04075 | S176 | Sugiyama | ALDOA ALDA | EHtPsALAIMENANVLARyAsICQQNGIVPIVEPEILPDGD |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04083 | S201 | Sugiyama | ANXA1 ANX1 LPC1 | LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04406 | Y314 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK |
| P04406 | Y320 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____ |
| P04406 | Y94 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | ItIFQERDPsKIKWGDAGAEyVVEstGVFttMEKAGAHLQG |
| P04792 | S187 | Sugiyama | HSPB1 HSP27 HSP28 | APMPKLAtQsNEItIPVtFEsRAQLGGPEAAKsDETAAK__ |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05187 | S192 | Sugiyama | ALPP PLAP | RVQHAsPAGtyAHtVNRNWysDADVPASARQEGCQDIATQL |
| P05198 | S219 | Sugiyama | EIF2S1 EIF2A | CYGYEGIDAVKEALRAGLNCsTENMPIKINLIAPPRYVMTT |
| P05362 | S43 | Sugiyama | ICAM1 | GPGNAQTSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETP |
| P05386 | S101 | Sugiyama | RPLP1 RRP1 | APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______ |
| P05386 | S104 | Sugiyama | RPLP1 RRP1 | tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________ |
| P05387 | S102 | Sugiyama | RPLP2 D11S2243E RPP2 | PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______ |
| P05387 | S105 | Sugiyama | RPLP2 D11S2243E RPP2 | GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________ |
| P05423 | S250 | Sugiyama | POLR3D BN51 BN51T | AKMKAPPKAARKTPGLPKDVsVAELLRELSLTKEEELLFLQ |
| P05783 | S177 | Sugiyama | KRT18 CYK18 PIG46 | ARLAADDFRVKyETELAMRQsVENDIHGLRKVIDDTNItRL |
| P06280 | S176 | Sugiyama | GLA | AQTFADWGVDLLKFDGCYCDsLENLADGYKHMSLALNRTGR |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S349 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV |
| P06733 | Y270 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV |
| P06733 | Y280 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD |
| P06733 | Y44 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK |
| P06744 | S22 | Sugiyama | GPI | AALTRDPQFQKLQQWyREHRsELNLRRLFDANKDRFNHFSL |
| P07195 | S106 | Sugiyama | LDHB | VtANSKIVVVtAGVRQQEGEsRLNLVQRNVNVFKFIIPQIV |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | S44 | Sugiyama | LDHB | ITVVGVGQVGMACAISILGKsLADELALVDVLEDKLKGEMM |
| P07205 | S390 | Sugiyama | PGK2 PGKB | VIGGGDTATCCAKWNtEDKVsHVstGGGAsLELLEGKILPG |
| P07205 | S399 | Sugiyama | PGK2 PGKB | CCAKWNtEDKVsHVstGGGAsLELLEGKILPGVEALSNM__ |
| P07205 | Y161 | Sugiyama | PGK2 PGKB | KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL |
| P07339 | S42 | Sugiyama | CTSD CPSD | VRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQAVPAV |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07384 | S474 | Sugiyama | CAPN1 CANPL1 PIG30 | GQPAVHLKRDFFLANAsRARsEQFINLREVSTRFRLPPGEY |
| P07437 | S115 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | sGAGNNWAKGHytEGAELVDsVLDVVRKEAESCDCLQGFQL |
| P07437 | S40 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | FWEVISDEHGIDPTGtyHGDsDLQLDRIsVyyNEAtGGKyV |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07900 | S165 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTK |
| P07900 | S169 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | TVITKHNDDEQyAWEssAGGsFtVRTDTGEPMGRGTKVILH |
| P07900 | S399 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK |
| P07900 | S52 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | LIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDs |
| P07900 | Y160 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGEPM |
| P07900 | Y309 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF |
| P07900 | Y313 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG |
| P08195 | S286 | Sugiyama | SLC3A2 MDU1 | KNQKDDVAQtDLLQIDPNFGsKEDFDsLLQsAKKKSIRVIL |
| P08195 | S403 | Sugiyama | SLC3A2 MDU1 | SDLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYL |
| P08195 | S518 | Sugiyama | SLC3A2 MDU1 | DIPGAVSANMTVKGQsEDPGsLLsLFRRLsDQRsKERSLLH |
| P08238 | S160 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | AEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTK |
| P08238 | S164 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | VVITKHNDDEQyAWEssAGGsFtVRADHGEPIGRGTKVILH |
| P08238 | S391 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S48 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG |
| P08238 | S532 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | yMtEPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK |
| P08238 | T537 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | IDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK |
| P08238 | Y155 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | SAYLVAEKVVVITKHNDDEQyAWEssAGGsFtVRADHGEPI |
| P08238 | Y301 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF |
| P08238 | Y305 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG |
| P08670 | S438 | Sugiyama | VIM | FssLNLREtNLDsLPLVDtHsKRTLLIKtVEtRDGQVINEt |
| P08708 | Y84 | Sugiyama | RPS17 RPS17L | GPVRGISIKLQEEERERRDNyVPEVsALDQEIIEVDPDtKE |
| P08758 | Y129 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | VLtEIIAsRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYY |
| P08758 | Y133 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | IIAsRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYYQRML |
| P09104 | Y44 | Sugiyama | ENO2 | LyTAKGLFRAAVPsGAstGIyEALELRDGDKQRYLGKGVLK |
| P09661 | S226 | Sugiyama | SNRPA1 | NAIANAstLAEVERLKGLLQsGQIPGRERRsGPtDDGEEEM |
| P09923 | S189 | Sugiyama | ALPI | RVQHAsPAGtyAHtVNRNWysDADMPASARQEGCQDIATQL |
| P09960 | S240 | Sugiyama | LTA4H LTA4 | LVWSEKEQVEKSAyEFsETEsMLKIAEDLGGPYVWGQYDLL |
| P09972 | S176 | Sugiyama | ALDOC ALDC | ERTPSALAILENANVLARyAsICQQNGIVPIVEPEILPDGD |
| P0CAP2 | S187 | Sugiyama | POLR2M GRINL1A | EASEHHPRHRVssQAEDtSssFDNLFIDRLQRITIADQGEQ |
| P0CG41 | S138 | Sugiyama | CTAGE8 | EKAAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKS |
| P0CG41 | S140 | Sugiyama | CTAGE8 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| P0CG47 | S57 | Sugiyama | UBB | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P0CG48 | S57 | Sugiyama | UBC | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGM |
| P10398 | S157 | Sugiyama | ARAF ARAF1 PKS PKS2 | SSKVPTVCVDMSTNRQQFyHsVQDLsGGsRQHEAPsNRPLN |
| P10636 | S396 | SIGNOR | MAPT MAPTL MTBT1 TAU | ARMVSKSKDGtGSDDKKAKTsTRSsAKtLKNRPCLsPKHPT |
| P10636 | S420 | SIGNOR | MAPT MAPTL MTBT1 TAU | sAKtLKNRPCLsPKHPTPGSsDPLIQPssPAVCPEPPssPK |
| P10696 | S189 | Sugiyama | ALPG ALPPL ALPPL2 | RVQHASPAGAYAHTVNRNWysDADVPASARQEGCQDIATQL |
| P10809 | S488 | Sugiyama | HSPD1 HSP60 | IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11142 | T163 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy |
| P11142 | Y431 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | TVLIKRNtTIPTKQtQtFttysDNQPGVLIQVyEGERAMTK |
| P11142 | Y443 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | KQtQtFttysDNQPGVLIQVyEGERAMTKDNNLLGKFELTG |
| P11279 | S141 | Sugiyama | LAMP1 | NLSDTHLFPNASSKEIKtVEsITDIRADIDKKYRCVSGTQV |
| P11586 | S318 | Sugiyama | MTHFD1 MTHFC MTHFD | FKPGKWMIQYNNLNLKTPVPsDIDIsRSCKPKPIGKLAREI |
| P11586 | S765 | Sugiyama | MTHFD1 MTHFC MTHFD | ARMFGIPVVVAVNAFKTDTEsELDLIsRLSREHGAFDAVKC |
| P12004 | S172 | Sugiyama | PCNA | sHIGDAVVIsCAKDGVKFSAsGELGNGNIKLSQTSNVDKEE |
| P12268 | S416 | Sugiyama | IMPDH2 IMPD2 | APGEYFFSDGIRLKKyRGMGsLDAMDKHLssQNRyFsEADK |
| P12814 | S744 | Sugiyama | ACTN1 | IARTINEVENQILtRDAKGIsQEQMNEFRAsFNHFDRDHsG |
| P13010 | S318 | Sugiyama | XRCC5 G22P2 | NDDDETEVLKEDIIQGFRyGsDIVPFSKVDEEQMKYKSEGK |
| P13489 | S178 | Sugiyama | RNH1 PRI RNH | SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP |
| P13489 | S225 | Sugiyama | RNH1 PRI RNH | KLEsCGVTSDNCRDLCGIVAsKASLRELALGSNKLGDVGMA |
| P13639 | S732 | Sugiyama | EEF2 EF2 | DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP |
| P13667 | S130 | Sugiyama | PDIA4 ERP70 ERP72 | DKDPPIPVAKIDAtsAsVLAsRFDVsGyPtIKILKKGQAVD |
| P13667 | S470 | Sugiyama | PDIA4 ERP70 ERP72 | FAIADEEDyAGEVKDLGLsEsGEDVNAAILDEsGKKFAMEP |
| P13667 | Y448 | Sugiyama | PDIA4 ERP70 ERP72 | RAATQFWRSKVLEVAKDFPEytFAIADEEDyAGEVKDLGLs |
| P13667 | Y458 | Sugiyama | PDIA4 ERP70 ERP72 | VLEVAKDFPEytFAIADEEDyAGEVKDLGLsEsGEDVNAAI |
| P13797 | S540 | Sugiyama | PLS3 | NDDIIVNWVNRTLSEAGKSTsIQSFKDKTISSSLAVVDLID |
| P13798 | S27 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | LsEPEEAAALyRGLSRQPALsAACLGPEVtTQyGGQyRTVH |
| P13798 | S304 | Sugiyama | APEH D3F15S2 D3S48E DNF15S2 | YVDLIGGKCELLSDDsLAVssPRLSPDQCRIVYLQYPSLIP |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P13929 | Y44 | Sugiyama | ENO3 | LHtAKGRFRAAVPsGAstGIyEALELRDGDKGRYLGKGVLK |
| P14314 | S126 | Sugiyama | PRKCSH G19P1 | yNsGVICENtCKEKGRKEREsLQQMAEVtREGFRLKKILIE |
| P14618 | S202 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs |
| P14618 | S205 | Sugiyama | PKM OIP3 PK2 PK3 PKM2 | VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD |
| P14625 | S109 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN |
| P14625 | S172 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | VGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSELI |
| P14625 | S447 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | PKyLNFVKGVVDsDDLPLNVsREtLQQHKLLKVIRKKLVRK |
| P14625 | S64 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR |
| P14625 | T171 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | GVGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSEL |
| P15311 | S535 | Sugiyama | EZR VIL2 | EKRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHN |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P16070 | S71 | Sugiyama | CD44 LHR MDU2 MDU3 MIC4 | DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17987 | S374 | Sugiyama | TCP1 CCT1 CCTA | ERICDDELILIKNTKARTsAsIILRGANDFMCDEMERSLHD |
| P17987 | S544 | Sugiyama | TCP1 CCT1 CCTA | ILRIDDLIKLHPESKDDKHGsyEDAVHsGALND________ |
| P18615 | S115 | Sugiyama | NELFE RD RDBP | KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs |
| P18615 | S139 | Sugiyama | NELFE RD RDBP | DLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEGPGAG |
| P18669 | S14 | Sugiyama | PGAM1 PGAMA CDABP0006 | _______MAAYKLVLIRHGEsAWNLENRFsGWyDADLsPAG |
| P18669 | S155 | Sugiyama | PGAM1 PGAMA CDABP0006 | NIsKDRRyADLtEDQLPsCEsLKDtIARALPFWNEEIVPQI |
| P18754 | S85 | Sugiyama | RCC1 CHC1 | IPEDVVQAEAGGMHTVCLSKsGQVysFGCNDEGALGRDtsV |
| P18850 | S98 | Sugiyama | ATF6 | NQICTVKDIKAEPQPLsPAssSYsVssPRSVDSYSSTQHVP |
| P19338 | S328 | Sugiyama | NCL | NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK |
| P19338 | S356 | Sugiyama | NCL | LAVVDVRIGMTRKFGyVDFEsAEDLEKALELtGLKVFGNEI |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P20618 | S151 | Sugiyama | PSMB1 PSC5 | PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA |
| P20618 | S157 | Sugiyama | PSMB1 PSC5 | IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL |
| P20674 | S104 | Sugiyama | COX5A | PEPKIIDAALRACRRLNDFAstVRILEVVKDKAGPHKEIYP |
| P21108 | S11 | Sugiyama | PRPS1L1 PRPS3 PRPSL | __________MPNIKIFsGssHQDLSQKIADRLGLELGKVV |
| P21108 | S8 | Sugiyama | PRPS1L1 PRPS3 PRPSL | _____________MPNIKIFsGssHQDLSQKIADRLGLELG |
| P21333 | S2152 | Sugiyama | FLNA FLN FLN1 | VKVTGEGRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQ |
| P21333 | S2158 | Sugiyama | FLNA FLN FLN1 | GRVKEsITRRRRAPsVANVGsHCDLsLKIPEIsIQDMtAQV |
| P22059 | S386 | Sugiyama | OSBP OSBP1 | ITMPENLGHKRtGsNIsGAssDIsLDEQyKHQLEETKKEKR |
| P22314 | S46 | Sugiyama | UBA1 A1S9T UBE1 | AQsVLsEVPSVPTNGMAKNGsEADIDEGLysRQLyVLGHEA |
| P22392 | Y151 | Sugiyama | NME2 NM23B | SLWFKPEELVDyKSCAHDWVyE___________________ |
| P22626 | S189 | Sugiyama | HNRNPA2B1 HNRPA2B1 | IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF |
| P22626 | S324 | Sugiyama | HNRNPA2B1 HNRPA2B1 | GNYNQQPSNYGPMKsGNFGGsRNMGGPyGGGNyGPGGsGGs |
| P23284 | S150 | Sugiyama | PPIB CYPB | LKHyGPGWVsMANAGKDTNGsQFFITTVKTAWLDGKHVVFG |
| P23528 | T70 | Sugiyama | CFL1 CFL | EEGKEILVGDVGQtVDDPyAtFVKMLPDKDCRyALyDAtyE |
| P23588 | S122 | Sugiyama | EIF4B | NLPyDVTEESIKEFFRGLNIsAVRLPREPsNPERLKGFGyA |
| P24534 | S174 | Sugiyama | EEF1B2 EEF1B EF1B | DMAKLEECVRsIQADGLVWGssKLVPVGyGIKKLQIQCVVE |
| P24539 | S142 | Sugiyama | ATP5PB ATP5F1 | DFADKLNEQKLAQLEEAKQAsIQHIQNAIDTEKsQQALVQK |
| P25054 | S1389 | Sugiyama | APC DP2.5 | PKsPPEHYVQETPLMFsRCTsVSsLDSFESRSIASSVQSEP |
| P25398 | S107 | Sugiyama | RPS12 | EWVGLCKIDREGKPRKVVGCsCVVVKDYGKESQAKDVIEEy |
| P25705 | S198 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK |
| P25705 | S76 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV |
| P25789 | T10 | Sugiyama | PSMA4 HC9 PSC9 | ___________MSRRyDsRttIFsPEGRLYQVEYAMEAIGH |
| P26038 | S144 | Sugiyama | MSN | LLASyAVQSKYGDFNKEVHKsGYLAGDKLLPQRVLEQHKLN |
| P26038 | S468 | Sugiyama | MSN | KAQMVQEDLEKTRAELKtAMstPHVAEPAENEQDEQDENGA |
| P26038 | T465 | Sugiyama | MSN | WQQKAQMVQEDLEKTRAELKtAMstPHVAEPAENEQDEQDE |
| P26232 | S667 | Sugiyama | CTNNA2 CAPR | YDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEEKAKIAEQV |
| P26373 | S106 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | IHKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLIL |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | T107 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | HKKVARTIGIsVDPRRRNKstEsLQANVQRLKEYRSKLILF |
| P27708 | S1859 | Sugiyama | CAD | RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | Y338 | Sugiyama | CALR CRTC | LWQVKSGTIFDNFLITNDEAyAEEFGNETWGVtKAAEKQMK |
| P27816 | S1073 | Sugiyama | MAP4 | DVKIEsQKLNFKEKAQAKVGsLDNVGHLPAGGAVKTEGGGS |
| P28066 | S172 | Sugiyama | PSMA5 | QLFHMDPsGtFVQCDARAIGsAsEGAQssLQEVyHKSMTLK |
| P28066 | S180 | Sugiyama | PSMA5 | GtFVQCDARAIGsAsEGAQssLQEVyHKSMTLKEAIKSSLI |
| P28838 | S180 | Sugiyama | LAP3 LAPEP PEPS | YEYDDLKQKKKMAVSAKLyGsGDQEAWQKGVLFAsGQNLAR |
| P28838 | S194 | Sugiyama | LAP3 LAPEP PEPS | SAKLyGsGDQEAWQKGVLFAsGQNLARQLMETPANEMTPtR |
| P29144 | S176 | Sugiyama | TPP2 | FDVANNGSsQANKLIKEELQsQVELLNsFEKKYSDPGPVYD |
| P29401 | S105 | Sugiyama | TKT | VWAEAGFLAEAELLNLRKIssDLDGHPVPKQAFtDVATGsL |
| P29401 | S443 | Sugiyama | TKT | EDGPSQMALEDLAMFRsVPtstVFyPsDGVAtEKAVELAAN |
| P29692 | S44 | Sugiyama | EEF1D EF1D | RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30086 | S54 | Sugiyama | PEBP1 PBP PEBP | VDELGKVLtPtQVKNRPtsIsWDGLDsGKLytLVLtDPDAP |
| P30101 | Y264 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | CPHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVM |
| P30101 | Y265 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | PHMTEDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVMM |
| P30101 | Y269 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | EDNKDLIQGKDLLIAyyDVDyEKNAKGSNYWRNRVMMVAKK |
| P30533 | S230 | Sugiyama | LRPAP1 A2MRAP | SDIKGSVLHSRHTELKEKLRsINQGLDRLRRVsHQGystEA |
| P30622 | S195 | Sugiyama | CLIP1 CYLN1 RSN | AAKEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIG |
| P30622 | S197 | Sugiyama | CLIP1 CYLN1 RSN | KEPsAtPPISNLTKtAsEsIsNLsEAGsIKKGERELKIGDR |
| P31327 | S537 | Sugiyama | CPS1 | GVELFKRGVLKEYGVKVLGtsVEsIMATEDRQLFSDKLNEI |
| P31327 | S835 | Sugiyama | CPS1 | MCHPsIEGFTPRLPMNKEWPsNLDLRKELSEPSsTRIyAIA |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P33176 | S57 | Sugiyama | KIF5B KNS KNS1 | DTVVIASKPYAFDRVFQSsTsQEQVyNDCAKKIVKDVLEGy |
| P34897 | S90 | Sugiyama | SHMT2 | GLELIAsENFCsRAALEALGsCLNNKYSEGYPGKRyyGGAE |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34932 | S76 | Sugiyama | HSPA4 APG2 HSPH2 | VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT |
| P35221 | S668 | Sugiyama | CTNNA1 | FDVRsRtsVQtEDDQLIAGQsARAIMAQLPQEQKAKIAEQV |
| P35241 | S533 | Sugiyama | RDX | ERVTETQKNERVKKQLQALssELAQARDETKKTQNDVLHAE |
| P35579 | S1892 | Sugiyama | MYH9 | LKQLKRQLEEAEEEAQRANAsRRKLQRELEDAtEtADAMNR |
| P35606 | S350 | Sugiyama | COPB2 | MGDAEIKDGERLPLAVKDMGsCEIyPQtIQHNPNGRFVVVC |
| P35613 | S229 | Sugiyama | BSG UNQ6505/PRO21383 | PMGTANIQLHGPPRVKAVKssEHINEGEtAMLVCKSEsVPP |
| P37802 | S163 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P38646 | T398 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | SDIGEVILVGGMTRMPKVQQtVQDLFGRAPsKAVNPDEAVA |
| P39019 | Y48 | Sugiyama | RPS19 | LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG |
| P39019 | Y54 | Sugiyama | RPS19 | VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs |
| P39023 | S13 | Sugiyama | RPL3 OK/SW-cl.32 | ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP |
| P40818 | S719 | Sugiyama | USP8 KIAA0055 UBPY | KPQIPAERDREPSKLKRsyssPDItQAIQEEEKRKPTVtPT |
| P40855 | S149 | Sugiyama | PEX19 HK33 PXF OK/SW-cl.22 | LKETLSGLAKNATDLQNssMsEEELTKAMEGLGMDEGDGEG |
| P41091 | T109 | Sugiyama | EIF2S3 EIF2G | YKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVRH |
| P42224 | S162 | Sugiyama | STAT1 | LDSKVRNVKDKVMCIEHEIKsLEDLQDEyDFKCKTLQNREH |
| P42677 | S78 | Sugiyama | RPS27 MPS1 | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| P43034 | S152 | Sugiyama | PAFAH1B1 LIS1 MDCR MDS PAFAHA | IKVWDyEtGDFERtLKGHtDsVQDIsFDHsGKLLASCSADM |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P43490 | S472 | Sugiyama | NAMPT PBEF PBEF1 | EYGQDLLHTVFKNGKVTKsysFDEIRKNAQLNIELEAAHH_ |
| P46013 | S1098 | Sugiyama | MKI67 | PAARVTGMKKWPRtPKEEAQsLEDLAGFKELFQtPGPsEEs |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46777 | S176 | Sugiyama | RPL5 MSTP030 | GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46783 | S146 | Sugiyama | RPS10 | TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_ |
| P46940 | S481 | Sugiyama | IQGAP1 KIAA0051 | ALINRALESGDVNTVWKQLsssVtGLTNIEEENCQRYLDEL |
| P46940 | S482 | Sugiyama | IQGAP1 KIAA0051 | LINRALESGDVNTVWKQLsssVtGLTNIEEENCQRYLDELM |
| P47712 | S729 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P49321 | S397 | Sugiyama | NASP | DGAVNGPsVVGDQtPIEPQtsIERLtEtKDGsGLEEKVRAK |
| P49321 | S659 | Sugiyama | NASP | IEELKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsst |
| P49321 | S662 | Sugiyama | NASP | LKELLPEIREKIEDAKEsQRsGNVAELALKATLVEsstsGF |
| P49327 | S265 | Sugiyama | FASN FAS | TILNAGTNTDGFKEQGVtFPsGDIQEQLIRSLyQsAGVAPE |
| P49327 | Y277 | Sugiyama | FASN FAS | KEQGVtFPsGDIQEQLIRSLyQsAGVAPEsFEyIEAHGtGT |
| P49327 | Y289 | Sugiyama | FASN FAS | QEQLIRSLyQsAGVAPEsFEyIEAHGtGTKVGDPQELNGIt |
| P49368 | S458 | Sugiyama | CCT3 CCTG TRIC5 | RAVAQALEVIPRTLIQNCGAstIRLLtSLRAKHtQENCEtW |
| P49588 | S775 | Sugiyama | AARS1 AARS | VTGAEAQKALRKAESLKKCLsVMEAKVKAQTAPNKDVQREI |
| P49589 | S307 | Sugiyama | CARS1 CARS | VPEAVGDQKALQEGEGDLsIsADRLsEKRSPNDFALWKASK |
| P49736 | S170 | Sugiyama | MCM2 BM28 CCNL1 CDCL1 KIAA0030 | KRRQVERAtEDGEEDEEMIEsIENLEDLKGHSVREWVsMAG |
| P49790 | S607 | Sugiyama | NUP153 | KtPPEDCEGPFRPAEILKEGsVLDILKsPGFAsPKIDSVAA |
| P50395 | S396 | Sugiyama | GDI2 RABGDIB | IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD |
| P50402 | S29 | Sugiyama | EMD EDMD STA | DtELttLLRRyNIPHGPVVGstRRLyEKKIFEyEtQRRRLs |
| P50402 | T30 | Sugiyama | EMD EDMD STA | tELttLLRRyNIPHGPVVGstRRLyEKKIFEyEtQRRRLsP |
| P50542 | S167 | Sugiyama | PEX5 PXR1 | EVTDPLSVSPARWAEEyLEQsEEKLWLGEPEGTATDRWYDE |
| P50851 | S1237 | Sugiyama | LRBA BGL CDC4L LBA | NLTRETKLINDCHGsVSEAssEQKIAKLDVsNVAtDtERLE |
| P50990 | S373 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | SEVGDTQVVVFKHEKEDGAIstIVLRGstDNLMDDIERAVD |
| P50990 | S380 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | VVVFKHEKEDGAIstIVLRGstDNLMDDIERAVDDGVNtFK |
| P51946 | S15 | Sugiyama | CCNH | ______MYHNsSQKRHWtFSsEEQLARLRADANRKFRCKAV |
| P51991 | S375 | Sugiyama | HNRNPA3 HNRPA3 | ssGsPyGGGyGsGGGsGGyGsRRF_________________ |
| P52298 | S13 | Sugiyama | NCBP2 CBP20 PIG55 | ________MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQE |
| P52298 | Y14 | Sugiyama | NCBP2 CBP20 PIG55 | _______MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQEK |
| P52597 | S187 | Sugiyama | HNRNPF HNRPF | KALGKHKERIGHRYIEVFKssQEEVRsysDPPLKFMsVQRP |
| P52597 | S63 | Sugiyama | HNRNPF HNRPF | VHFIYTREGRQsGEAFVELGsEDDVKMALKKDRESMGHRyI |
| P52788 | S57 | Sugiyama | SMS | ESVHTWQDHGYLATYTNKNGsFANLRIYPHGLVLLDLQSYD |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P53621 | S389 | Sugiyama | COPA | SYNPAENAVLLCTRAsNLENstyDLytIPKDADsQNPDAPE |
| P54105 | S42 | Sugiyama | CLNS1A CLCI ICLN | DTEAVLNGKGLGtGtLyIAEsRLSWLDGsGLGFSLEYPTIS |
| P54252 | S260 | Sugiyama | ATXN3 ATX3 MJD MJD1 SCA3 | IDMEDEEADLRRAIQLsMQGssRNIsQDMtQtsGTNLTSEE |
| P54577 | S366 | Sugiyama | YARS1 YARS | KQKPMAKGPAKNsEPEEVIPsRLDIRVGKIITVEKHPDADs |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P55036 | S266 | Sugiyama | PSMD4 MCB1 | AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ |
| P55769 | S122 | Sugiyama | SNU13 NHP2L1 | CSVTIKEGSQLKQQIQsIQQsIERLLV______________ |
| P55854 | S27 | Sugiyama | SUMO3 SMT3A SMT3H1 | KEGVKTENDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC |
| P55957 | S78 | Sugiyama | BID | QtDGNRssHsRLGRIEADsEsQEDIIRNIARHLAQVGDsMD |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60174 | T217 | Sugiyama | TPI1 TPI | VsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLVGGAsL |
| P60709 | Y218 | Sugiyama | ACTB | ysFtttAEREIVRDIKEKLCyVALDFEQEMAtAAssssLEK |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60891 | S11 | Sugiyama | PRPS1 | __________MPNIKIFsGssHQDLSQKIADRLGLELGKVV |
| P60891 | S8 | Sugiyama | PRPS1 | _____________MPNIKIFsGssHQDLSQKIADRLGLELG |
| P60900 | S175 | Sugiyama | PSMA6 PROS27 | DPAGyyCGFKATAAGVKQtEstsFLEKKVKKKFDWTFEQTV |
| P61081 | S175 | Sugiyama | UBE2M UBC12 | NNRRLFEQNVQRSMRGGyIGstyFERCLK____________ |
| P61163 | T248 | Sugiyama | ACTR1A CTRN1 | PQKDETLETEKAQyyLPDGstIEIGPSRFRAPELLFRPDLI |
| P61313 | S97 | Sugiyama | RPL15 EC45 TCBAP0781 | KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN |
| P61326 | S106 | Sugiyama | MAGOH MAGOHA | QELEIVIGDEHISFTTSKIGsLIDVNQSKDPEGLRVFYYLV |
| P61916 | S29 | Sugiyama | NPC2 HE1 | LLLALSTAAQAEPVQFKDCGsVDGVIKEVNVsPCPtQPCQL |
| P61956 | S28 | Sugiyama | SUMO2 SMT3B SMT3H2 | EGVKtENNDHINLKVAGQDGsVVQFKIKRHTPLSKLMKAYC |
| P61978 | S401 | Sugiyama | HNRNPK HNRPK | GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P62241 | S115 | Sugiyama | RPS8 OK/SW-cl.83 | TLVKNCIVLIDStPYRQWyEsHyALPLGRKKGAKLtPEEEE |
| P62241 | S160 | Sugiyama | RPS8 OK/SW-cl.83 | KRSKKIQKKYDERKKNAKIssLLEEQFQQGKLLACIASRPG |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S117 | Sugiyama | YWHAE | CCDILDVLDKHLIPAANtGEsKVFyyKMKGDYHRyLAEFAt |
| P62258 | S156 | Sugiyama | YWHAE | AtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLGLALN |
| P62258 | S233 | Sugiyama | YWHAE | syKDstLIMQLLRDNLtLWtsDMQGDGEEQNKEALQDVEDE |
| P62269 | S96 | Sugiyama | RPS18 D6S218E | QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK |
| P62277 | S12 | Sugiyama | RPS13 | _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62906 | S64 | Sugiyama | RPL10A NEDD6 | QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH |
| P62937 | Y79 | Sugiyama | PPIA CYPA | GFMCQGGDFtRHNGTGGKsIyGEKFEDENFILKHtGPGILs |
| P62979 | S57 | Sugiyama | RPS27A UBA80 UBCEP1 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGA |
| P62987 | S57 | Sugiyama | UBA52 UBCEP2 | PPDQQRLIFAGKQLEDGRtLsDyNIQKEstLHLVLRLRGGI |
| P63104 | T30 | Sugiyama | YWHAZ | AKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAyKN |
| P63165 | S61 | Sugiyama | SUMO1 SMT3C SMT3H3 UBL1 OK/SW-cl.43 | TTHLKKLKESYCQRQGVPMNsLRFLFEGQRIADNHtPKELG |
| P63220 | S65 | Sugiyama | RPS21 | RFNGQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF__ |
| P63220 | S68 | Sugiyama | RPS21 | GQFKtyAICGAIRRMGEsDDsILRLAKADGIVSKNF_____ |
| P63220 | Y53 | Sugiyama | RPS21 | QMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRLA |
| P63261 | Y218 | Sugiyama | ACTG1 ACTG | ysFtttAEREIVRDIKEKLCyVALDFEQEMAtAAssssLEK |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P67936 | T241 | Sugiyama | TPM4 | EEKLAQAKEENVGLHQtLDQtLNELNCI_____________ |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68363 | Y432 | Sugiyama | TUBA1B | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| P68363 | Y451 | Sugiyama | TUBA1B | DyEEVGVDsVEGEGEEEGEEy____________________ |
| P78371 | S144 | Sugiyama | CCT2 99D8.1 CCTB | QTIIAGWREATKAAREALLssAVDHGsDEVKFRQDLMNIAG |
| P78371 | S470 | Sugiyama | CCT2 99D8.1 CCTB | IADNAGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAI |
| P83731 | S38 | Sugiyama | RPL24 | GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK |
| P83731 | S86 | Sugiyama | RPL24 | EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE |
| P83731 | T83 | Sugiyama | RPL24 | QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA |
| P84098 | S37 | Sugiyama | RPL19 | CGKKKVWLDPNEtNEIANANsRQQIRKLIKDGLIIRKPVtV |
| Q00587 | S350 | Sugiyama | CDC42EP1 BORG5 CEP1 MSE55 | HyPEMDARQERVEVLPQARAsWEsLDEEWRAPQAGsRtPVP |
| Q00613 | S375 | Sugiyama | HSF1 HSTF1 | TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL |
| Q01082 | S1388 | Sugiyama | SPTBN1 SPTB2 | TTQTKAQRLFDANKAELFtQsCADLDKWLHGLESQIQSDDy |
| Q01105 | S161 | Sugiyama | SET | FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK |
| Q01105 | S166 | Sugiyama | SET | yFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQT |
| Q01105 | S168 | Sugiyama | SET | ENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQN |
| Q01105 | T169 | Sugiyama | SET | NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK |
| Q01581 | S404 | Sugiyama | HMGCS1 HMGCS | YSLKVTQDATPGSALDKITAsLCDLKSRLDSRTGVAPDVFA |
| Q01650 | S31 | Sugiyama | SLC7A5 CD98LC LAT1 MPE16 | LAAPAAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNIT |
| Q02878 | S255 | Sugiyama | RPL6 TXREB1 | tEKEKYEITEQRKIDQKAVDsQILPKIKAIPQLQGYLRSVF |
| Q04637 | S1238 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | RDAVKREAALPPVsPLKAALsEEELEKKsKAIIEEyLHLND |
| Q04721 | S359 | Sugiyama | NOTCH2 | IDDCAFASCTPGSTCIDRVAsFSCMCPEGKAGLLCHLDDAC |
| Q04726 | S622 | Sugiyama | TLE3 KIAA1547 | VWDLHNQTLVRQFQGHTDGAsCIDISHDGTKLWTGGLDNTV |
| Q06210 | S261 | Sugiyama | GFPT1 GFAT GFPT | GsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDA |
| Q06830 | S152 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV |
| Q06830 | T143 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF |
| Q07020 | T136 | Sugiyama | RPL18 | AGGKILtFDQLALDsPKGCGtVLLsGPRKGREVYRHFGKAP |
| Q07666 | S20 | Sugiyama | KHDRBS1 SAM68 | _MQRRDDPAARMsRssGRsGsMDPsGAHPsVRQtPsRQPPL |
| Q07960 | S50 | Sugiyama | ARHGAP1 CDC42GAP RHOGAP1 | EKNWPsDEMPDFPKsDDsKsssPELVtHLKWDDPyyDIARH |
| Q08209 | S492 | Sugiyama | PPP3CA CALNA CNA | EAKGLDRINERMPPRRDAMPsDANLNsINKALTSETNGTDS |
| Q08378 | S476 | Sugiyama | GOLGA3 | SHSSQQRQDsLsSEVDTLKQsCWDLERAMTDLQNMLEAKNA |
| Q08378 | S501 | Sugiyama | GOLGA3 | ERAMTDLQNMLEAKNAsLAssNNDLQVAEEQyQRLMAKVED |
| Q08378 | S739 | Sugiyama | GOLGA3 | HLDLMKQLTLTQEALQSREQsLDALQTHyDELQARLGELQG |
| Q08AD1 | S1313 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | sLNtGDNEsVHsGKRtPRsEsVEGFLsPsRCGsRNGEKDWE |
| Q08AD1 | S464 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | FDKEDSVQRstPNRGITRsIsNEGLtLNNsHVsKHIRKNLS |
| Q09028 | S146 | Sugiyama | RBBP4 RBAP48 | EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE |
| Q09028 | S147 | Sugiyama | RBBP4 RBAP48 | VNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGEC |
| Q09666 | S220 | Sugiyama | AHNAK PM227 | QsGKtVIRLPsGsGAAsPtGsAVDIRAGAIsAsGPELQGAG |
| Q10471 | S536 | Sugiyama | GALNT2 | NDSRQKWEQIEGNSKLRHVGsNLCLDSRTAKSGGLSVEVCG |
| Q12888 | S1618 | Sugiyama | TP53BP1 | EQYGLGPYEAVtPLtKAADIsLDNLVEGKRKRRsNVssPAt |
| Q12931 | S361 | Sugiyama | TRAP1 HSP75 HSPC5 | SIFYVPDMKPSMFDVSRELGsSVALYSRKVLIQTKATDILP |
| Q13136 | S1156 | Sugiyama | PPFIA1 LIP1 | RAPSWRKKFRPKDIRGLAAGsAEtLPANFRVtssMssPsMQ |
| Q13136 | S338 | Sugiyama | PPFIA1 LIP1 | MEERITTLEKRYLAAQREATsVHDLNDKLENEIANKDSMHR |
| Q13164 | T553 | Sugiyama | MAPK7 BMK1 ERK5 PRKM7 | KRRQERERKERGAGASGGPStDPLAGLVLsDNDRsLLERWT |
| Q13200 | S147 | Sugiyama | PSMD2 TRAP2 | SVLAMTMSGERECLKYRLVGsQEELASWGHEYVRHLAGEVA |
| Q13243 | S153 | Sugiyama | SRSF5 HRS SFRS5 SRP40 | EVTFADAHRPKLNEGVVEFAsYGDLKNAIEKLSGKEINGRK |
| Q13263 | S784 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK |
| Q13283 | S250 | Sugiyama | G3BP1 G3BP | sssPAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGI |
| Q13283 | S253 | Sugiyama | G3BP1 G3BP | PAPADIAQtVQEDLRtFsWAsVtsKNLPPSGAVPVTGIPPH |
| Q13470 | S502 | SIGNOR|PSP | TNK1 | PPARGQRRNMPLERMKGIsRsLEsVLsLGPRPtGGGssPPE |
| Q13509 | S115 | Sugiyama | TUBB3 TUBB4 | SGAGNNWAKGHytEGAELVDsVLDVVRKECENCDCLQGFQL |
| Q13615 | S613 | Sugiyama | MTMR3 KIAA0371 ZFYVE10 | YPAPGTSPDDPPLSRLPKtRsyDNLttACDNTVPLASRRCs |
| Q13625 | S480 | Sugiyama | TP53BP2 ASPP2 BBP | FDAVDQSNAPPSFGTLRKNQssEDILRDAQVANKNVAKVPP |
| Q13765 | S186 | Sugiyama | NACA HSD48 | sEEEEVDEtGVEVKDIELVMsQANVsRAKAVRALKNNSNDI |
| Q13885 | S115 | Sugiyama | TUBB2A TUBB2 | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q14008 | S1873 | Sugiyama | CKAP5 KIAA0097 | LyEyKKKYsDADIEPFLKNSsQFFQSYVERGLRVIEMEREG |
| Q14152 | S492 | Sugiyama | EIF3A EIF3S10 KIAA0139 | VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ |
| Q14157 | S360 | Sugiyama | UBAP2L KIAA0144 NICE4 | sMLGKGFGDVGEAKGGsttGsQFLEQFKTAQALAQLAAQHS |
| Q14192 | S238 | Sugiyama | FHL2 DRAL SLIM3 | AKKCAGCTNPISGLGGtKyIsFEERQWHNDCFNCKKCsLsL |
| Q14192 | S257 | Sugiyama | FHL2 DRAL SLIM3 | IsFEERQWHNDCFNCKKCsLsLVGRGFLTERDDILCPDCGK |
| Q14204 | S3257 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | NDKLKKMVKDQQEAEKKKVMsQEIQEQLHKQQEVIADKQMS |
| Q14498 | S336 | Sugiyama | RBM39 HCC1 RNPC2 | LAGRPMKVGHVTERtDAssAssFLDsDELERtGIDLGtTGR |
| Q14568 | S165 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | AEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTK |
| Q14568 | S169 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | TVITKHNDDEQyAWEssAGGsFtVRTDTGERMGRGTKVILH |
| Q14568 | S52 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | LIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDS |
| Q14568 | Y160 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | SAYLVAEKVTVITKHNDDEQyAWEssAGGsFtVRTDTGERM |
| Q14677 | S163 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | DRLREERKKAKKNKDKyVGVssDsVGGFRysERYDPEPKSK |
| Q14677 | S210 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | KNKSAFPFSDKLGELsDKIGstIDDtIsKFRRKDREDsPER |
| Q14738 | S598 | Sugiyama | PPP2R5D | DVyTIKALEAHKRAEEFLTAsQEAL________________ |
| Q14789 | S1568 | Sugiyama | GOLGB1 | RDKLITEMDRSLLENQSLSssCEsLKLALEGLTEDKEKLVK |
| Q14974 | S531 | Sugiyama | KPNB1 NTF97 | LETTDRPDGHQNNLRSSAyEsLMEIVKNSAKDCYPAVQKTT |
| Q14980 | S1181 | Sugiyama | NUMA1 NMP22 NUMA | DsALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQD |
| Q15021 | S1333 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | APsAKKPSTGSRyQPLAstAsDNDFVtPEPRRTTRRHPNTQ |
| Q15084 | S377 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | PAMAAINARKMKFALLKGsFsEQGINEFLRELsFGRGstAP |
| Q15172 | S472 | Sugiyama | PPP2R5A | EELWKKLEELKLKKALEKQNsAyNMHSILSNTSAE______ |
| Q15181 | S127 | Sugiyama | PPA1 IOPPP PP | NDKHTGCCGDNDPIDVCEIGsKVCARGEIIGVKVLGILAMI |
| Q15276 | S407 | Sugiyama | RABEP1 RAB5EP RABPT5 RABPT5A | GDPFSKSDNDMFKDGLRRAQstDsLGtsGsLQSKALGYNYK |
| Q15293 | S80 | Sugiyama | RCN1 RCN | HEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGDGFVt |
| Q15459 | S451 | Sugiyama | SF3A1 SAP114 | IGLLDPRWLEQRDRSIREKQsDDEVyAPGLDIESsLKQLAE |
| Q15459 | S465 | Sugiyama | SF3A1 SAP114 | SIREKQsDDEVyAPGLDIESsLKQLAERRtDIFGVEETAIG |
| Q15642 | S296 | Sugiyama | TRIP10 CIP4 STOT STP | FARPGDVEFEDFsQPMNRAPsDssLGtPsDGRPELRGPGRS |
| Q15751 | S1514 | Sugiyama | HERC1 | AESRLVHtsPNYRLIKsRsEsDLsQPEsDEEGYALsGRRNV |
| Q15785 | S8 | Sugiyama | TOMM34 URCC3 | _____________MAPKFPDsVEELRAAGNESFRNGQyAEA |
| Q15818 | S91 | Sugiyama | NPTX1 | TILSQKETIRELTAKLGRCEsQsTLDPGAGEARAGGGRKQP |
| Q16204 | S325 | Sugiyama | CCDC6 D10S170 TST1 | QRKLQREMERREALCRQLsEsEssLEMDDERYFNEMsAQGL |
| Q16513 | S583 | Sugiyama | PKN2 PRK2 PRKCL2 | VTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQDs |
| Q16513 | S590 | Sugiyama | PKN2 PRK2 PRKCL2 | LEPEPPPAPPRAssLGEIDEssELRVLDIPGQDsEtVFDIQ |
| Q16531 | T1125 | Sugiyama | DDB1 XAP1 | MQEVVANLQYDDGSGMKREAtADDLIKVVEELtRIH_____ |
| Q16576 | S145 | Sugiyama | RBBP7 RBAP46 | EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE |
| Q16576 | S146 | Sugiyama | RBBP7 RBAP46 | VNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGEC |
| Q16658 | S234 | Sugiyama | FSCN1 FAN1 HSN SNL | LEFRsGKVAFRDCEGRyLAPsGPsGtLKAGKATKVGKDELF |
| Q16836 | S196 | Sugiyama | HADH HAD HAD1 HADHSC SCHAD | PVMKLVEVIKTPMTSQKTFEsLVDFSKALGKHPVSCKDTPG |
| Q53EL6 | S46 | Sugiyama | PDCD4 H731 | GDEENAGTEEIKNEINGNWIsAssINEARINAKAKRRLRKN |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF7 | S405 | Sugiyama | HSP90AB3P HSP90BC | YMTEPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKK |
| Q58FF7 | T410 | Sugiyama | HSP90AB3P HSP90BC | IDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEESK |
| Q5BKZ1 | Y93 | Sugiyama | ZNF326 ZIRD | PYESyDsRsSLGGRDLYRsGyGFNEPEQSRFGGSYGGRFES |
| Q5JSH3 | S565 | Sugiyama | WDR44 RPH11 | DYFNNMRMKYNtEGRVsPsPsQEsLsssKsDTDtGVCsGtD |
| Q5T035 | S66 | Sugiyama | FAM120A2P C9orf129 | LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERSLPI |
| Q5T035 | T62 | Sugiyama | FAM120A2P C9orf129 | yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER |
| Q5VT52 | S1070 | Sugiyama | RPRD2 KIAA0460 HSPC099 | TATDQQQQEEHYRIETRVsssCLDLPDSTEEKGAPIETLGy |
| Q5VWQ8 | S747 | Sugiyama | DAB2IP AF9Q34 AIP1 KIAA1743 | ssysEANEPDLQMANGGKsLsMVDLQDARTLDGEAGsPAGP |
| Q6EEV6 | S28 | Sugiyama | SUMO4 SMT3H4 | EEVKTENNNHINLKVAGQDGsVVQFKIKRQTPLSKLMKAYC |
| Q6FI81 | S170 | Sugiyama | CIAPIN1 CUA001 PRO0915 | ESDNLLFVQITGKKPNFEVGsSRQLKLsITKKssPsVKPAV |
| Q6FI81 | S305 | Sugiyama | CIAPIN1 CUA001 PRO0915 | CAsCPyLGMPAFKPGEKVLLsDsNLHDA_____________ |
| Q6NVY1 | S381 | Sugiyama | HIBCH | PADLKEVtEEDLNNHFKSLGsSDLKF_______________ |
| Q6P2E9 | S967 | Sugiyama | EDC4 HEDLS | PEDWPALIWQQQRELAELRHsQEELLQRLCTQLEGLQSTVT |
| Q6PID6 | S19 | Sugiyama | TTC33 | __MASFGWKRKIGEKVSKVTsQQFEAEAADEKDVVDNDEGN |
| Q6S8J3 | Y918 | Sugiyama | POTEE A26C1A POTE2 | YRFTTMAEREIVRDIKEKLCyVALDFEQEMAtAAssssLEK |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q6ZRY4 | S60 | Sugiyama | RBPMS2 | VDIKPRELYLLFRPFKGYEGsLIKLTARQPVGFVIFDSRAG |
| Q71U36 | Y432 | Sugiyama | TUBA1A TUBA3 | GMEEGEFSEAREDMAALEKDyEEVGVDsVEGEGEEEGEEy_ |
| Q71U36 | Y451 | Sugiyama | TUBA1A TUBA3 | DyEEVGVDsVEGEGEEEGEEy____________________ |
| Q71UM5 | S78 | Sugiyama | RPS27L | GCSTVLCQPTGGKARLtEGCsFRRKQH______________ |
| Q7Z2W4 | S492 | Sugiyama | ZC3HAV1 ZC3HDC2 PRO1677 | VQATGRIADDADPRVALVNDsLsDVtsTtssRVDDHDSEEI |
| Q7Z401 | S186 | Sugiyama | DENND4A IRLB MYCPBP | PSKGESPPHTFCKVDKNLNNsMWGsAVyLCyKKSVAKTNTV |
| Q7Z401 | S190 | Sugiyama | DENND4A IRLB MYCPBP | ESPPHTFCKVDKNLNNsMWGsAVyLCyKKSVAKTNTVSYKA |
| Q7Z401 | Y193 | Sugiyama | DENND4A IRLB MYCPBP | PHTFCKVDKNLNNsMWGsAVyLCyKKSVAKTNTVSYKAGLI |
| Q7Z401 | Y196 | Sugiyama | DENND4A IRLB MYCPBP | FCKVDKNLNNsMWGsAVyLCyKKSVAKTNTVSYKAGLICRY |
| Q7Z417 | S608 | Sugiyama | NUFIP2 KIAA1321 PIG1 | sGALsLEPsHIGDLQKADtssQGALVFLSKDYEIEsQNPLA |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q7Z417 | S655 | Sugiyama | NUFIP2 KIAA1321 PIG1 | LGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsIWNL |
| Q7Z417 | S671 | Sugiyama | NUFIP2 KIAA1321 PIG1 | DsWGsFDLRAAIVYHTKEMEsIWNLQKQDPKRIItyNEAMD |
| Q7Z460 | S1196 | Sugiyama | CLASP1 KIAA0622 MAST1 | EEIYSSLRGVTEAIEKFsFRsQEDLNEPIKRDGKKECDIVs |
| Q7Z460 | S545 | Sugiyama | CLASP1 KIAA0622 MAST1 | yHTLESSyQKALQSHLKNSDsIVsLPQsDRsssssQEsLNR |
| Q86TC9 | S197 | Sugiyama | MYPN MYOP | ACKNHKSKLESQNKVMQENSssFsDLSERRERSSVPIPIPA |
| Q86TC9 | S198 | Sugiyama | MYPN MYOP | CKNHKSKLESQNKVMQENSssFsDLSERRERSSVPIPIPAD |
| Q86UF2 | S138 | Sugiyama | CTAGE6 CTAGE6P | EKAAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKS |
| Q86UF2 | S140 | Sugiyama | CTAGE6 CTAGE6P | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q86V81 | S239 | Sugiyama | ALYREF ALY BEF THOC4 | tRGGARGRGRGAGRNSKQQLsAEELDAQLDAyNARMDts__ |
| Q86V81 | S8 | Sugiyama | ALYREF ALY BEF THOC4 | _____________MADKMDMsLDDIIKLNRSQRGGRGGGRG |
| Q86VQ1 | S226 | Sugiyama | GLCCI1 | sCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQRSKQ |
| Q86W92 | S636 | Sugiyama | PPFIBP1 KIAA1230 | RGGTRATAGPRLGWsRDLGQsNsDLDMPFAKWTKEQVCNWL |
| Q86X02 | S318 | Sugiyama | CDR2L HUMPPA | AQDGVssPAAsPGHVVRKsCsDTALNAIVAKDPASRHAGNL |
| Q8IWW6 | S656 | Sugiyama | ARHGAP12 | RRPTLQAVREKGYIKDQVFGsNLANLCQRENGTVPKFVKLC |
| Q8IWZ3 | S122 | Sugiyama | ANKHD1 KIAA1085 MASK VBARP PP2500 | EVEsFILDQEDLDNPVLKTTsEIFLSSTAEGADLRTVDPET |
| Q8IX94 | S138 | Sugiyama | CTAGE4 | EKAAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKS |
| Q8IX94 | S140 | Sugiyama | CTAGE4 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q8IYB3 | S240 | Sugiyama | SRRM1 SRM160 | tPELPEPsVKVKEPsVQEAtstsDILKVPKPEPIPEPKEPs |
| Q8IZP0 | S22 | Sugiyama | ABI1 SSH3BP1 | AELQMLLEEEIPSGKRALIEsyQNLTRVADyCENNyIQATD |
| Q8N806 | S265 | Sugiyama | UBR7 C14orf130 | KDDVREVKVEQNsEPCAGsssEsDLQtVFKNESLNAESKSG |
| Q8NBJ7 | S256 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG |
| Q8TDD1 | S624 | Sugiyama | DDX54 | FQQGQQGRQEQQEGPVGPAPsRPALQEKQPEKEEEEEAGEs |
| Q8TEU7 | S1116 | Sugiyama | RAPGEF6 PDZGEF2 | LNAKKLYEDAQMARKVKQYLssLDVETDEEKFQMMSLQWEP |
| Q8WU90 | S351 | Sugiyama | ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 | DIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLsEAs |
| Q8WU90 | T348 | Sugiyama | ZC3H15 DFRP1 LEREPO4 HSPC303 HT010 MSTP012 PP730 | sVNDIDLSLYIPRDVDEtGItVAsLERFSTYTsDKDENKLs |
| Q8WUF5 | S253 | Sugiyama | PPP1R13L IASPP NKIP1 PPP1R13BL RAI | PLRAQDDLTLRRRPPKAWNEsDLDVAyEKKPSQTAsyERLD |
| Q8WWH5 | S268 | Sugiyama | TRUB1 PUS4 | ECGGGFYIRSLVSDIGKELSsCANVLELTRTKQGPFTLEEH |
| Q8WWI1 | S1510 | Sugiyama | LMO7 FBX20 FBXO20 KIAA0858 | RsAsVNKEPVSLPGIMRRGEsLDNLDsPRSNSWRQPPWLNQ |
| Q8WWI1 | S704 | Sugiyama | LMO7 FBX20 FBXO20 KIAA0858 | KKRLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEM |
| Q8WWI1 | S706 | Sugiyama | LMO7 FBX20 FBXO20 KIAA0858 | RLMVERLFQKIYGENGsKsMsDVsAEDVQNLRQLRYEEMQK |
| Q8WXH0 | S2781 | Sugiyama | SYNE2 KIAA1011 NUA | ILSQIRKCKVTHDGILARQQsVEsLAEEVKDKVPSLTTYEG |
| Q92609 | S541 | Sugiyama | TBC1D5 KIAA0210 | EsMPVQLNKGLSSKNIsssPsVEsLPGGREFtGsPPssAtK |
| Q92626 | S1300 | Sugiyama | PXDN KIAA0230 MG50 PRG2 PXD01 VPO VPO1 | NITRVQSDVFRVAEFPHGyGsCDEIPRVDLRVWQDCCEDCR |
| Q92973 | S339 | Sugiyama | TNPO1 KPNB2 MIP1 TRN | SDIDIILLKGDVEEDEtIPDsEQDIRPRFHRSRTVAQQHDE |
| Q92974 | S711 | Sugiyama | ARHGEF2 KIAA0651 LFP40 | sGGNtsPGVtANGEARTFNGsIELCRADsDssQRDRNGNQL |
| Q93062 | S53 | Sugiyama | RBPMS HERMES | LDIKPRELYLLFRPFKGYEGsLIKLTSKQPVGFVSFDSRSE |
| Q96A72 | S108 | Sugiyama | MAGOHB MAGOH2 | QELEIVIGDEHISFTTSKIGsLIDVNQSKDPEGLRVFYYLV |
| Q96D15 | S98 | Sugiyama | RCN3 UNQ239/PRO272 | ARLGRIVDRMDRAGDGDGWVsLAELRAWIAHTQQRHIRDsV |
| Q96EY7 | S651 | Sugiyama | PTCD3 MRPS39 TRG15 | VELASAFSLPICEGLTQRVMsDFAINQEQKEALsNLtALts |
| Q96FC9 | S277 | Sugiyama | DDX11 CHL1 CHLR1 KRG2 | LVSLGSRQNLCVNEDVKSLGsVQLINDRCVDMQRSRHEKKK |
| Q96JP5 | S177 | Sugiyama | ZFP91 ZNF757 FKSG11 | TSVSRHRDTENTRSSRSKTGsLQLICKSEPNTDQLDYDVGE |
| Q96KP4 | S58 | Sugiyama | CNDP2 CN2 CPGL HEL-S-13 PEPA | RGEIRRMMEVAAADVKQLGGsVELVDIGKQKLPDGSEIPLP |
| Q96L34 | S26 | EPSD | MARK4 KIAA1860 MARKL1 | VLAPGNDRNSDTHGTLGSGRsSDKGPSWSSRSLGARCRNsI |
| Q96L34 | S423 | Sugiyama | MARK4 KIAA1860 MARKL1 | TSHSKGQRSSSSTYHRQRRHsDFCGPsPAPLHPKRsPtSTG |
| Q96L34 | S429 | Sugiyama | MARK4 KIAA1860 MARKL1 | QRSSSSTYHRQRRHsDFCGPsPAPLHPKRsPtSTGEAELKE |
| Q96L34 | S45 | Sugiyama | MARK4 KIAA1860 MARKL1 | RsSDKGPSWSSRSLGARCRNsIAsCPEEQPHVGNYRLLRTI |
| Q96L34 | S48 | Sugiyama | MARK4 KIAA1860 MARKL1 | DKGPSWSSRSLGARCRNsIAsCPEEQPHVGNYRLLRTIGKG |
| Q96L34 | S494 | Sugiyama | MARK4 KIAA1860 MARKL1 | PMVSSAHNPNKAEIPERRKDsTsTPNNLPPSMMTRRNTYVC |
| Q96L34 | S496 | Sugiyama | MARK4 KIAA1860 MARKL1 | VSSAHNPNKAEIPERRKDsTsTPNNLPPSMMTRRNTYVCTE |
| Q96L34 | S543 | Sugiyama | MARK4 KIAA1860 MARKL1 | PSLLPNGKENSSGtPRVPPAsPssHSLAPPsGERsRLARGS |
| Q96L34 | S545 | Sugiyama | MARK4 KIAA1860 MARKL1 | LLPNGKENSSGtPRVPPAsPssHSLAPPsGERsRLARGSTI |
| Q96L34 | S546 | Sugiyama | MARK4 KIAA1860 MARKL1 | LPNGKENSSGtPRVPPAsPssHSLAPPsGERsRLARGSTIR |
| Q96L34 | S553 | Sugiyama | MARK4 KIAA1860 MARKL1 | SSGtPRVPPAsPssHSLAPPsGERsRLARGSTIRSTFHGGQ |
| Q96L34 | S557 | Sugiyama | MARK4 KIAA1860 MARKL1 | PRVPPAsPssHSLAPPsGERsRLARGSTIRSTFHGGQVRDR |
| Q96L34 | S99 | Sugiyama | MARK4 KIAA1860 MARKL1 | ILTGREVAIKIIDKTQLNPSsLQKLFREVRIMKGLNHPNIV |
| Q96L34 | T214 | EPSD | MARK4 KIAA1860 MARKL1 | NIKIADFGFSNEFTLGSKLDtFCGsPPYAAPELFQGKKYDG |
| Q96L34 | T536 | Sugiyama | MARK4 KIAA1860 MARKL1 | ERPGAERPSLLPNGKENSSGtPRVPPAsPssHSLAPPsGER |
| Q96N67 | S1438 | Sugiyama | DOCK7 KIAA1771 | LGTYTIAsPPERsPsGsAFGsQENLRWRKDMTHWRQNTEKL |
| Q96PK6 | S520 | Sugiyama | RBM14 SIP | AAAAYGAQPSATLAAPYRtQssAsLAAsYAAQQHPQAAASY |
| Q96PK6 | S620 | Sugiyama | RBM14 SIP | KRYGSDRRLAELsDYRRLsEsQLsFRRsPtKSSLDYRRLPD |
| Q96S59 | S613 | Sugiyama | RANBP9 RANBPM | DCDtEMEVDSsQLRRQLCGGsQAAIERMIHFGRELQAMSEQ |
| Q99426 | S163 | Sugiyama | TBCB CG22 CKAP1 | AEAAQRLAEEKAQASSIPVGsRCEVRAAGQSPRRGTVMYVG |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q9BQE3 | Y432 | Sugiyama | TUBA1C TUBA6 | GMEEGEFSEAREDMAALEKDyEEVGADsADGEDEGEEy___ |
| Q9BQE3 | Y449 | Sugiyama | TUBA1C TUBA6 | EKDyEEVGADsADGEDEGEEy____________________ |
| Q9BRG2 | S180 | Sugiyama | SH2D3A NSP1 UNQ175/PRO201 | EDPAGMEASTMPISALPRtssDPVLLKAPAPLGTVADsLRA |
| Q9BT78 | S18 | Sugiyama | COPS4 CSN4 | ___MAAAVRQDLAQLMNSsGsHKDLAGKYRQILEKAIQLSG |
| Q9BVA1 | S115 | Sugiyama | TUBB2B | sGAGNNWAKGHytEGAELVDsVLDVVRKESESCDCLQGFQL |
| Q9BVJ6 | S453 | Sugiyama | UTP14A SDCCAG16 | RsELsQDAEPAGsQEtKDsGsQEVLsELRVLSQKLKENHQS |
| Q9BWG6 | S199 | Sugiyama | SCNM1 | PAPMsPtRRRALDHyLTLRSsGWIPDGRGRWVKDENVEFDs |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9BZC7 | S1371 | Sugiyama | ABCA2 ABC2 KIAA1062 | sGEGHAGNLARCSELTQSQAsLQSASSVGSARGDEGAGYTD |
| Q9C0C2 | S1158 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | sPssKMEGGHFVPPGKttAGsVDWTDQLGLRNLEVssCVGs |
| Q9C0C7 | S628 | Sugiyama | AMBRA1 DCAF3 KIAA1736 | SVPSSGSQLPPLERTEGQTPsSsRLELsssAsPQEERTVGV |
| Q9C0C7 | S630 | Sugiyama | AMBRA1 DCAF3 KIAA1736 | PSSGSQLPPLERTEGQTPsSsRLELsssAsPQEERTVGVAF |
| Q9H0H5 | S257 | Sugiyama | RACGAP1 KIAA1478 MGCRACGAP | ETVPYWtRSRRKtGtLQPWNsDstLNSRQLEPRTETDsVGt |
| Q9H2G2 | S518 | Sugiyama | SLK KIAA0204 STK2 | tVDLVSQEtGEKEANIQAVDsEVGLTKEDtQEKLGEDDKTQ |
| Q9H2J4 | S151 | Sugiyama | PDCL3 PhLP2A VIAF1 | NQHLSGLARKFPDVKFIKAIsTTCIPNYPDRNLPTIFVYLE |
| Q9H501 | S77 | Sugiyama | ESF1 ABTAP C20orf6 HDCMC28P | GRPISHSTTEDLKRFyDLsDsDsNLsGEDSKALSQKKIKKK |
| Q9H6H4 | S152 | Sugiyama | REEP4 C8orf20 PP432 | AAVQAATKSQGALAGRLRsFsMQDLRSISDAPAPAyHDPLy |
| Q9H7D7 | S121 | Sugiyama | WDR26 CDW2 MIP2 PRO0852 | ASSSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLN |
| Q9H7D7 | S123 | Sugiyama | WDR26 CDW2 MIP2 PRO0852 | SSLATPELGSSLKKKKRLsQsDEDVIRLIGQHLNGLGLNQT |
| Q9H7E9 | T40 | Sugiyama | C8orf33 | PCAsRGARLPGPVsSARNPstVCLCPEQPTCSNADSRAHPL |
| Q9HA77 | S548 | Sugiyama | CARS2 OK/SW-cl.10 | TLRRGLTAHGINIKDRssttstWELLDQRTKDQKSAG____ |
| Q9HBE1 | S564 | Sugiyama | PATZ1 PATZ RIAZ ZBTB19 ZNF278 ZSG | TYGNKEGQKCSHQDPIESSDsYGDLSDASDLKTPEKQSANG |
| Q9HCN4 | S301 | Sugiyama | GPN1 MBDIN RPAP4 XAB1 HUSSY-23 | ANAESQQQREQLERLRKDMGsVALDAGtAKDsLsPVLHPsD |
| Q9HCN8 | S40 | Sugiyama | SDF2L1 UNQ1941/PRO4424 | ALLVPGGGAAKTGAELVTCGsVLKLLNTHHRVRLHSHDIKY |
| Q9HD42 | S101 | Sugiyama | CHMP1A CHMP1 KIAA0047 PCOLN3 PRSM1 | TMKGVTKNMAQVTKALDKALsTMDLQKVSSVMDRFEQQVQN |
| Q9NP61 | S457 | Sugiyama | ARFGAP3 ARFGAP1 | sQADYETRARLERLsAsssIssADLFEEPRKQPAGNysLSS |
| Q9NQ39 | S157 | Sugiyama | RPS10P5 RPS10L | TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_ |
| Q9NTJ3 | S504 | Sugiyama | SMC4 CAPC SMC4L1 | ELMGFSKSVNEARSKMDVAQsELDIyLSRHNTAVSQLTKAK |
| Q9NW64 | S142 | Sugiyama | RBM22 ZC3H16 199G4 | EREISNsDGTRPVGMLGKATsTsDMLLKLARTTPYYKRNRP |
| Q9NY27 | S315 | Sugiyama | PPP4R2 SBBI57 | HCtEEDEEEDEEEEEEsFMtsREMIPERKNQEKESDDALTV |
| Q9NYB9 | S22 | Sugiyama | ABI2 ARGBPIA | AELQMLLEEEIPGGRRALFDsytNLERVADyCENNyIQSAD |
| Q9NZB2 | S417 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERssPI |
| Q9NZB2 | T413 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | yPysLSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyER |
| Q9P1Y5 | S431 | Sugiyama | CAMSAP3 KIAA1543 | FGLDSDVDVVMGDPVLLRsVssDsLGPPRPAPARTPtQPPP |
| Q9P265 | S203 | Sugiyama | DIP2B KIAA1463 | stsssASSTLSHGEVKGtsGsLADVFANtRIENFSAPPDVT |
| Q9UBF8 | S428 | Sugiyama | PI4KB PIK4CB | NFDTTSVPARIPENRIRstRsVENLPECGItHEQRAGSFST |
| Q9UBU9 | S223 | Sugiyama | NXF1 TAP | ELKPEQVEQLKLIMSKRYDGsQQALDLKGLRSDPDLVAQNI |
| Q9UGU0 | S1187 | Sugiyama | TCF20 KIAA0292 SPBP | sDGLPNKGMELKHGSQKLQEsCWDLsRQTsPAKSSGPPGMS |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UII2 | S63 | Sugiyama | ATP5IF1 ATPI ATPIF1 | AGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEIVHHKK |
| Q9UJF2 | S803 | Sugiyama | RASAL2 NGAP | NPVyHLNNPIPAMPKASIDssLENLSTAssRSQSNSEDFKL |
| Q9UNF1 | S85 | Sugiyama | MAGED2 BCG1 | KAtEVsKtPEAREAPAtQAssttQLtDtQVLAAENKSLAAD |
| Q9UNF1 | T81 | Sugiyama | MAGED2 BCG1 | SGVSKAtEVsKtPEAREAPAtQAssttQLtDtQVLAAENKS |
| Q9UNZ2 | S189 | Sugiyama | NSFL1C UBXN2C | AGEKRQHssQDVHVVLKLWKsGFsLDNGELRSyQDPsNAQF |
| Q9UNZ2 | S74 | Sugiyama | NSFL1C UBXN2C | SQATPssVsRGTAPSDNRVtsFRDLIHDQDEDEEEEEGQRF |
| Q9UPQ0 | S1054 | Sugiyama | LIMCH1 KIAA1102 | YFHIQCFRCGICKGQLGDAVsGTDVRIRNGLLNCNDCyMRS |
| Q9UQ35 | S1541 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | ssVDQKtVARtPLGQRsRsGssQELDVKPsAsPQERsEsDs |
| Q9UQ35 | S2692 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS |
| Q9Y2B0 | S115 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | QIDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKF |
| Q9Y2B0 | S116 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | IDPstHRKNYVRVVGRNGEssELDLQGIRIDsDISGtLKFA |
| Q9Y2B0 | S178 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | NVKDKLCSKRtDLCDHALHIsHDEL________________ |
| Q9Y2B0 | S63 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | AQVDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLE |
| Q9Y2I7 | S307 | Sugiyama | PIKFYVE KIAA0981 PIP5K3 | TRLVSVQEDAGKsPARNRsAsItNLsLDRsGsPMVPSYEts |
| Q9Y2L1 | S633 | Sugiyama | DIS3 KIAA1008 RRP44 | LNKLAKILKKRRIEKGALTLssPEVRFHMDSETHDPIDLQT |
| Q9Y3B8 | S203 | Sugiyama | REXO2 SFN SMFN CGI-114 | EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK |
| Q9Y3F4 | S153 | Sugiyama | STRAP MAWD UNRIP | EAEPKEISGHTSGIKKALWCsEDKQILsADDKtVRLWDHAT |
| Q9Y3F4 | T109 | Sugiyama | STRAP MAWD UNRIP | VSGDELMTLAHKHIVKtVDFtQDSNyLLtGGQDKLLRIYDL |
| Q9Y450 | S65 | Sugiyama | HBS1L HBS1 KIAA1038 | RDKPsVEPVEEyDyEDLKEssNsVsNHQLSGFDQARLYsCL |
| Q9Y490 | S1535 | Sugiyama | TLN1 KIAA1027 TLN | RTTNPTAKRQFVQSAKEVANsTANLVKTIKALDGAFTEENR |
| Q9Y4G6 | S1537 | Sugiyama | TLN2 KIAA0320 | KTANPVAKRHFVQSAKEVANsTANLVKTIKALDGDFSEDNR |
| Q9Y4L1 | S742 | Sugiyama | HYOU1 GRP170 HSPH4 ORP150 | KLQDLTLRDLEKQEREKAANsLEAFIFEtQDKLyQPEyQEV |
| Q9Y4L1 | T750 | Sugiyama | HYOU1 GRP170 HSPH4 ORP150 | DLEKQEREKAANsLEAFIFEtQDKLyQPEyQEVsTEEQREE |
| Q9Y4W2 | S642 | Sugiyama | LAS1L MSTP060 | NARLLAQKRGALQGsAWQVssEDVRWDTFPLGRMPGQTEDP |
| Q9Y4X5 | S514 | Sugiyama | ARIH1 ARI MOP6 UBCH7BP HUSSY-27 | NQADLENATEVLSGYLERDIsQDsLQDIKQKVQDKYRYCES |
| Q9Y5S2 | S474 | Sugiyama | CDC42BPB KIAA1124 | KLELSRKLQESTQTVQsLHGsSRALSNsNRDKEIKKLNEEI |
| Q9Y617 | S226 | Sugiyama | PSAT1 PSA | GVTVVIVRDDLLGFALRECPsVLEyKVQAGNSSLYNTPPCF |
| Q9Y6E0 | S400 | Sugiyama | STK24 MST3 STK3 | ISPLFAELKEKsQACGGNLGsIEELRGAIYLAEEACPGISD |
| Q9Y6Y8 | T893 | Sugiyama | SEC23IP MSTP053 | GFISSLKSAWQTLNEFARAHtsstQLQEELEKVANQIKEEE |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Signal Transduction | R-HSA-162582 | 8.927038e-09 | 8.049 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 4.404146e-07 | 6.356 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 7.350169e-07 | 6.134 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 3.940735e-06 | 5.404 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 5.404929e-06 | 5.267 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 3.607463e-05 | 4.443 | 0 | 0 |
| Kinesins | R-HSA-983189 | 3.502421e-05 | 4.456 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 4.231633e-05 | 4.373 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 3.973365e-05 | 4.401 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 4.527474e-05 | 4.344 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 9.053439e-05 | 4.043 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 8.932540e-05 | 4.049 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 1.148584e-04 | 3.940 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.149359e-04 | 3.940 | 0 | 0 |
| M Phase | R-HSA-68886 | 1.877293e-04 | 3.726 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 2.751722e-04 | 3.560 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 3.069102e-04 | 3.513 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 2.818087e-04 | 3.550 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 3.022277e-04 | 3.520 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 3.090397e-04 | 3.510 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 3.318136e-04 | 3.479 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 3.318136e-04 | 3.479 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 4.261012e-04 | 3.370 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 4.261012e-04 | 3.370 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 4.994441e-04 | 3.302 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 4.709163e-04 | 3.327 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 4.336852e-04 | 3.363 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 4.709163e-04 | 3.327 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 4.859812e-04 | 3.313 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 4.573633e-04 | 3.340 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 5.196922e-04 | 3.284 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 5.318660e-04 | 3.274 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 5.457074e-04 | 3.263 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 5.565895e-04 | 3.254 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 6.415424e-04 | 3.193 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 6.031238e-04 | 3.220 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 6.371783e-04 | 3.196 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 6.371783e-04 | 3.196 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 6.280027e-04 | 3.202 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 7.155585e-04 | 3.145 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 7.304644e-04 | 3.136 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 7.359693e-04 | 3.133 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 7.626160e-04 | 3.118 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.016180e-03 | 2.993 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.062964e-03 | 2.973 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 1.034590e-03 | 2.985 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 1.190814e-03 | 2.924 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 1.292461e-03 | 2.889 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.329548e-03 | 2.876 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.385052e-03 | 2.859 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.527052e-03 | 2.816 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.527052e-03 | 2.816 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.477093e-03 | 2.831 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.446555e-03 | 2.840 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.477093e-03 | 2.831 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 1.811452e-03 | 2.742 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 1.826602e-03 | 2.738 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.904646e-03 | 2.720 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 1.940619e-03 | 2.712 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.987756e-03 | 2.702 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 2.115360e-03 | 2.675 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 2.183347e-03 | 2.661 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 2.392932e-03 | 2.621 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.442623e-03 | 2.612 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 2.473730e-03 | 2.607 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 2.667257e-03 | 2.574 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 2.955408e-03 | 2.529 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.841132e-03 | 2.547 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 2.984510e-03 | 2.525 | 1 | 1 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 3.101720e-03 | 2.508 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 3.065220e-03 | 2.514 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 3.019498e-03 | 2.520 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 3.234481e-03 | 2.490 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.243615e-03 | 2.489 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 3.267407e-03 | 2.486 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 3.450748e-03 | 2.462 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 3.699175e-03 | 2.432 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 3.699175e-03 | 2.432 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 3.699175e-03 | 2.432 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 3.699175e-03 | 2.432 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 3.617366e-03 | 2.442 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 3.992869e-03 | 2.399 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 4.008332e-03 | 2.397 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 4.363924e-03 | 2.360 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 4.332733e-03 | 2.363 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 4.363924e-03 | 2.360 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 4.378203e-03 | 2.359 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 4.649698e-03 | 2.333 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 4.649744e-03 | 2.333 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 4.893056e-03 | 2.310 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 4.893056e-03 | 2.310 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 5.177189e-03 | 2.286 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 4.913760e-03 | 2.309 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 5.624232e-03 | 2.250 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 5.909716e-03 | 2.228 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 6.322462e-03 | 2.199 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 6.572491e-03 | 2.182 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 6.744658e-03 | 2.171 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 6.964581e-03 | 2.157 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 6.986191e-03 | 2.156 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 7.316548e-03 | 2.136 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 7.316548e-03 | 2.136 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 7.659325e-03 | 2.116 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 8.333329e-03 | 2.079 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 8.265447e-03 | 2.083 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 8.031885e-03 | 2.095 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 8.031885e-03 | 2.095 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 8.335885e-03 | 2.079 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 9.660718e-03 | 2.015 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 9.660718e-03 | 2.015 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 9.660718e-03 | 2.015 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 9.660718e-03 | 2.015 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 9.496849e-03 | 2.022 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 9.526451e-03 | 2.021 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 9.577820e-03 | 2.019 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 9.699280e-03 | 2.013 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 8.822706e-03 | 2.054 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 9.526451e-03 | 2.021 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 8.883829e-03 | 2.051 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.026988e-02 | 1.988 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 1.037449e-02 | 1.984 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 1.141459e-02 | 1.943 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 1.153568e-02 | 1.938 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 1.265697e-02 | 1.898 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 1.265697e-02 | 1.898 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.281108e-02 | 1.892 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 1.296412e-02 | 1.887 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 1.202048e-02 | 1.920 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.307835e-02 | 1.883 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 1.307835e-02 | 1.883 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.324717e-02 | 1.878 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 1.324717e-02 | 1.878 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.788637e-02 | 1.747 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.788637e-02 | 1.747 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.788637e-02 | 1.747 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.788637e-02 | 1.747 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.788637e-02 | 1.747 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 1.828433e-02 | 1.738 | 0 | 0 |
| RSK activation | R-HSA-444257 | 1.828433e-02 | 1.738 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 1.828433e-02 | 1.738 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.792670e-02 | 1.746 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.792670e-02 | 1.746 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 1.792670e-02 | 1.746 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 1.792670e-02 | 1.746 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 1.374048e-02 | 1.862 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 1.815387e-02 | 1.741 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.706669e-02 | 1.768 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.477899e-02 | 1.830 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 1.564289e-02 | 1.806 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 1.674003e-02 | 1.776 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 1.374048e-02 | 1.862 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 1.674003e-02 | 1.776 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 1.674003e-02 | 1.776 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 1.815387e-02 | 1.741 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 1.576133e-02 | 1.802 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 1.542861e-02 | 1.812 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.652901e-02 | 1.782 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 1.663803e-02 | 1.779 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 1.663803e-02 | 1.779 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 1.850423e-02 | 1.733 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.902333e-02 | 1.721 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 1.913093e-02 | 1.718 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 1.934837e-02 | 1.713 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 1.946048e-02 | 1.711 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 1.946048e-02 | 1.711 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 1.950634e-02 | 1.710 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.984211e-02 | 1.702 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 1.984211e-02 | 1.702 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 1.991637e-02 | 1.701 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 1.992013e-02 | 1.701 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 1.992013e-02 | 1.701 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.021824e-02 | 1.694 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 2.113401e-02 | 1.675 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 2.286874e-02 | 1.641 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 2.286874e-02 | 1.641 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 2.286874e-02 | 1.641 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 2.286874e-02 | 1.641 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 2.286874e-02 | 1.641 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 2.329301e-02 | 1.633 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 2.113401e-02 | 1.675 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 2.177263e-02 | 1.662 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 2.336742e-02 | 1.631 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 2.362849e-02 | 1.627 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 2.362849e-02 | 1.627 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 2.362849e-02 | 1.627 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 2.362849e-02 | 1.627 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 2.362849e-02 | 1.627 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 2.362849e-02 | 1.627 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 2.362849e-02 | 1.627 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 2.367047e-02 | 1.626 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 2.475850e-02 | 1.606 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 2.535171e-02 | 1.596 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 2.535171e-02 | 1.596 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 2.656137e-02 | 1.576 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 2.823881e-02 | 1.549 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 2.823881e-02 | 1.549 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 2.716230e-02 | 1.566 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 2.716230e-02 | 1.566 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 2.790978e-02 | 1.554 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 2.716230e-02 | 1.566 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 2.656625e-02 | 1.576 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.615410e-02 | 1.582 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 2.823881e-02 | 1.549 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 2.884125e-02 | 1.540 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 2.680769e-02 | 1.572 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.854694e-02 | 1.544 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 2.615410e-02 | 1.582 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 2.887774e-02 | 1.539 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 2.893560e-02 | 1.539 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 3.043282e-02 | 1.517 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 3.118578e-02 | 1.506 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 3.147432e-02 | 1.502 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 3.147432e-02 | 1.502 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 3.150170e-02 | 1.502 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 3.179954e-02 | 1.498 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 3.197178e-02 | 1.495 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 3.214588e-02 | 1.493 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 3.286729e-02 | 1.483 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 3.286729e-02 | 1.483 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 3.291964e-02 | 1.483 | 1 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 3.396309e-02 | 1.469 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 3.367391e-02 | 1.473 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 3.396309e-02 | 1.469 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.396309e-02 | 1.469 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 3.862260e-02 | 1.413 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 3.574298e-02 | 1.447 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 3.795634e-02 | 1.421 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 3.385166e-02 | 1.470 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 3.625189e-02 | 1.441 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 3.438728e-02 | 1.464 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 3.366627e-02 | 1.473 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 3.709031e-02 | 1.431 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 3.913029e-02 | 1.407 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 3.935049e-02 | 1.405 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.935049e-02 | 1.405 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 3.968119e-02 | 1.401 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 4.009947e-02 | 1.397 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 4.009947e-02 | 1.397 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 4.009947e-02 | 1.397 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 4.010369e-02 | 1.397 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 4.124761e-02 | 1.385 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 4.279802e-02 | 1.369 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 4.381371e-02 | 1.358 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 4.381371e-02 | 1.358 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 4.381371e-02 | 1.358 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 4.381371e-02 | 1.358 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 4.419044e-02 | 1.355 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 4.419044e-02 | 1.355 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 4.419044e-02 | 1.355 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 4.419044e-02 | 1.355 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 4.559734e-02 | 1.341 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 4.562444e-02 | 1.341 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 4.562444e-02 | 1.341 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 4.648676e-02 | 1.333 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 4.960812e-02 | 1.304 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 4.912868e-02 | 1.309 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 4.912868e-02 | 1.309 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 4.759454e-02 | 1.322 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 5.310586e-02 | 1.275 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 5.310586e-02 | 1.275 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 5.025589e-02 | 1.299 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 5.453649e-02 | 1.263 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 5.085610e-02 | 1.294 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 5.563287e-02 | 1.255 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 5.563287e-02 | 1.255 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 5.586082e-02 | 1.253 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 5.310586e-02 | 1.275 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 4.728559e-02 | 1.325 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 5.567846e-02 | 1.254 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 5.091422e-02 | 1.293 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 5.310586e-02 | 1.275 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 5.586082e-02 | 1.253 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 5.374749e-02 | 1.270 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 4.724415e-02 | 1.326 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 4.937847e-02 | 1.306 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 4.976868e-02 | 1.303 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 5.262632e-02 | 1.279 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 4.750630e-02 | 1.323 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 5.607315e-02 | 1.251 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 5.607315e-02 | 1.251 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 5.607315e-02 | 1.251 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 5.607315e-02 | 1.251 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 5.624532e-02 | 1.250 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 5.624532e-02 | 1.250 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 5.748582e-02 | 1.240 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 5.789278e-02 | 1.237 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 5.803328e-02 | 1.236 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 5.803328e-02 | 1.236 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 5.925912e-02 | 1.227 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 6.076175e-02 | 1.216 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 6.102922e-02 | 1.214 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 6.266022e-02 | 1.203 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 6.266022e-02 | 1.203 | 0 | 0 |
| TGFBR3 regulates FGF2 signaling | R-HSA-9839397 | 6.359330e-02 | 1.197 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 6.450131e-02 | 1.190 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 6.459332e-02 | 1.190 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 6.459332e-02 | 1.190 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 6.496153e-02 | 1.187 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 6.530412e-02 | 1.185 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 6.567440e-02 | 1.183 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 6.593875e-02 | 1.181 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 7.149509e-02 | 1.146 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 6.961877e-02 | 1.157 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 6.973619e-02 | 1.157 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 8.270109e-02 | 1.082 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 8.270109e-02 | 1.082 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.270109e-02 | 1.082 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 6.768595e-02 | 1.170 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 6.768595e-02 | 1.170 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 7.324961e-02 | 1.135 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 7.660625e-02 | 1.116 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 6.768595e-02 | 1.170 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 7.224065e-02 | 1.141 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 6.961877e-02 | 1.157 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 6.966922e-02 | 1.157 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 7.202234e-02 | 1.143 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 6.966922e-02 | 1.157 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 7.890368e-02 | 1.103 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 8.217136e-02 | 1.085 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 6.735972e-02 | 1.172 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 7.300370e-02 | 1.137 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 6.630590e-02 | 1.178 | 1 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.604823e-02 | 1.119 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 6.732392e-02 | 1.172 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 6.974581e-02 | 1.156 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 8.300135e-02 | 1.081 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 8.300135e-02 | 1.081 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 8.300135e-02 | 1.081 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 8.300135e-02 | 1.081 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 8.300135e-02 | 1.081 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 8.420747e-02 | 1.075 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 8.453726e-02 | 1.073 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 8.480482e-02 | 1.072 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 8.480482e-02 | 1.072 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 8.505446e-02 | 1.070 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 8.505446e-02 | 1.070 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 8.542033e-02 | 1.068 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 8.572286e-02 | 1.067 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 8.912735e-02 | 1.050 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 8.912735e-02 | 1.050 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 8.912735e-02 | 1.050 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 9.004939e-02 | 1.046 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 9.113550e-02 | 1.040 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 9.172961e-02 | 1.037 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 9.326794e-02 | 1.030 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 9.401713e-02 | 1.027 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 9.417857e-02 | 1.026 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 9.502113e-02 | 1.022 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 9.532796e-02 | 1.021 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 9.610412e-02 | 1.017 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 9.655643e-02 | 1.015 | 0 | 0 |
| PKA activation | R-HSA-163615 | 9.690944e-02 | 1.014 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 9.690944e-02 | 1.014 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 9.690944e-02 | 1.014 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 9.690944e-02 | 1.014 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 9.693496e-02 | 1.014 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 9.693496e-02 | 1.014 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 9.693496e-02 | 1.014 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 9.693496e-02 | 1.014 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 9.741575e-02 | 1.011 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 9.838177e-02 | 1.007 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 9.840061e-02 | 1.007 | 0 | 0 |
| Loss of function of TP53 in cancer due to loss of tetramerization ability | R-HSA-9723905 | 1.270522e-01 | 0.896 | 0 | 0 |
| Loss of Function of TP53 in Cancer | R-HSA-9723907 | 1.270522e-01 | 0.896 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.270522e-01 | 0.896 | 0 | 0 |
| Regulation of TP53 Expression | R-HSA-6804754 | 1.036532e-01 | 0.984 | 0 | 0 |
| TWIK related potassium channel (TREK) | R-HSA-1299503 | 1.036532e-01 | 0.984 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 1.254638e-01 | 0.901 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 1.032893e-01 | 0.986 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 1.032893e-01 | 0.986 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 1.198743e-01 | 0.921 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 1.198743e-01 | 0.921 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 1.198743e-01 | 0.921 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 1.123273e-01 | 0.950 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 1.289068e-01 | 0.890 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 1.185763e-01 | 0.926 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 1.185763e-01 | 0.926 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 1.088950e-01 | 0.963 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.220533e-01 | 0.913 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 1.220533e-01 | 0.913 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.010655e-01 | 0.995 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 1.107077e-01 | 0.956 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.014959e-01 | 0.994 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 1.028090e-01 | 0.988 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 9.970975e-02 | 1.001 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 1.314434e-01 | 0.881 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.020901e-01 | 0.991 | 0 | 0 |
| Protein folding | R-HSA-391251 | 1.090123e-01 | 0.963 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 1.286392e-01 | 0.891 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 1.113127e-01 | 0.953 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.076006e-01 | 0.968 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.241928e-01 | 0.906 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 1.220533e-01 | 0.913 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 1.123273e-01 | 0.950 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 1.114850e-01 | 0.953 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 1.010655e-01 | 0.995 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 1.123273e-01 | 0.950 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 1.228421e-01 | 0.911 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.066875e-01 | 0.972 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 1.241928e-01 | 0.906 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 1.028090e-01 | 0.988 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 1.028090e-01 | 0.988 | 0 | 0 |
| Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization | R-HSA-180897 | 1.036532e-01 | 0.984 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 1.032893e-01 | 0.986 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.015814e-01 | 0.993 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 1.015814e-01 | 0.993 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.198743e-01 | 0.921 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 1.178250e-01 | 0.929 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 1.307115e-01 | 0.884 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 1.043676e-01 | 0.981 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 1.028902e-01 | 0.988 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.032893e-01 | 0.986 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.293850e-01 | 0.888 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 1.019427e-01 | 0.992 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 1.032893e-01 | 0.986 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 1.039108e-01 | 0.983 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 1.157504e-01 | 0.936 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 1.323178e-01 | 0.878 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 1.330312e-01 | 0.876 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.334467e-01 | 0.875 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 1.337288e-01 | 0.874 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 1.350992e-01 | 0.869 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 1.362473e-01 | 0.866 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 1.366650e-01 | 0.864 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 1.389341e-01 | 0.857 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 1.395886e-01 | 0.855 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 1.395886e-01 | 0.855 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 1.418854e-01 | 0.848 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 1.418854e-01 | 0.848 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 1.418854e-01 | 0.848 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 1.418854e-01 | 0.848 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 1.418854e-01 | 0.848 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 1.436151e-01 | 0.843 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.446517e-01 | 0.840 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 1.446517e-01 | 0.840 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 1.457510e-01 | 0.836 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 1.465873e-01 | 0.834 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 1.465873e-01 | 0.834 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 1.465873e-01 | 0.834 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 1.479292e-01 | 0.830 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.479295e-01 | 0.830 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 1.481386e-01 | 0.829 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 1.486515e-01 | 0.828 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 1.486515e-01 | 0.828 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 1.486515e-01 | 0.828 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 1.486515e-01 | 0.828 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 1.486515e-01 | 0.828 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 1.497392e-01 | 0.825 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 1.497392e-01 | 0.825 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 1.497392e-01 | 0.825 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 1.502681e-01 | 0.823 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.507295e-01 | 0.822 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 1.507295e-01 | 0.822 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 1.521936e-01 | 0.818 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.527626e-01 | 0.816 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 1.559169e-01 | 0.807 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 1.565775e-01 | 0.805 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 1.565775e-01 | 0.805 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.565775e-01 | 0.805 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 1.565775e-01 | 0.805 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 1.565775e-01 | 0.805 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 1.966880e-01 | 0.706 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.966880e-01 | 0.706 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 1.966880e-01 | 0.706 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.897627e-01 | 0.722 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 1.754804e-01 | 0.756 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 1.754804e-01 | 0.756 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 2.245178e-01 | 0.649 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 2.245178e-01 | 0.649 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 2.245178e-01 | 0.649 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 2.245178e-01 | 0.649 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 1.606121e-01 | 0.794 | 0 | 0 |
| FGFR3 mutant receptor activation | R-HSA-2033514 | 2.025903e-01 | 0.693 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 2.025903e-01 | 0.693 | 0 | 0 |
| Signaling by activated point mutants of FGFR3 | R-HSA-1839130 | 2.025903e-01 | 0.693 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 2.025903e-01 | 0.693 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 1.652973e-01 | 0.782 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 1.652973e-01 | 0.782 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 2.308283e-01 | 0.637 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 2.308283e-01 | 0.637 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 2.060737e-01 | 0.686 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 1.666920e-01 | 0.778 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.666920e-01 | 0.778 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.666920e-01 | 0.778 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 2.302334e-01 | 0.638 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.843982e-01 | 0.734 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.843982e-01 | 0.734 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 1.823279e-01 | 0.739 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 2.219539e-01 | 0.654 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 2.219539e-01 | 0.654 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 1.948074e-01 | 0.710 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 2.165101e-01 | 0.665 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 2.133889e-01 | 0.671 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 2.115205e-01 | 0.675 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 1.833653e-01 | 0.737 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 1.833653e-01 | 0.737 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 2.200371e-01 | 0.658 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.807094e-01 | 0.743 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 2.089248e-01 | 0.680 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 2.266723e-01 | 0.645 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.683537e-01 | 0.774 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 2.359600e-01 | 0.627 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 2.089248e-01 | 0.680 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 2.189845e-01 | 0.660 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 2.346700e-01 | 0.630 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 2.264332e-01 | 0.645 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 2.235973e-01 | 0.651 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 2.308283e-01 | 0.637 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 1.621151e-01 | 0.790 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 1.966880e-01 | 0.706 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 1.652973e-01 | 0.782 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 1.849562e-01 | 0.733 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.622308e-01 | 0.790 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.966880e-01 | 0.706 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 1.948074e-01 | 0.710 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 2.126791e-01 | 0.672 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 1.646168e-01 | 0.784 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 2.314493e-01 | 0.636 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 2.003802e-01 | 0.698 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.723514e-01 | 0.764 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 2.315514e-01 | 0.635 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.592532e-01 | 0.798 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 1.666920e-01 | 0.778 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 2.359179e-01 | 0.627 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 2.245178e-01 | 0.649 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 2.245178e-01 | 0.649 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 1.828190e-01 | 0.738 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 2.219539e-01 | 0.654 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 1.696896e-01 | 0.770 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 2.022091e-01 | 0.694 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 1.661829e-01 | 0.779 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 2.031169e-01 | 0.692 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 1.966880e-01 | 0.706 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 2.235973e-01 | 0.651 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 2.235973e-01 | 0.651 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.264332e-01 | 0.645 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 1.621151e-01 | 0.790 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 2.025903e-01 | 0.693 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.652973e-01 | 0.782 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 2.344468e-01 | 0.630 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 1.948074e-01 | 0.710 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 2.025903e-01 | 0.693 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 1.942181e-01 | 0.712 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 2.344468e-01 | 0.630 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 2.060737e-01 | 0.686 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 1.754804e-01 | 0.756 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 1.865400e-01 | 0.729 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 2.359600e-01 | 0.627 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 2.302334e-01 | 0.638 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 2.025903e-01 | 0.693 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 2.060737e-01 | 0.686 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 2.315514e-01 | 0.635 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 2.302334e-01 | 0.638 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 1.606121e-01 | 0.794 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 2.267619e-01 | 0.644 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.620812e-01 | 0.790 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.991198e-01 | 0.701 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 2.189691e-01 | 0.660 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 2.308283e-01 | 0.637 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.670456e-01 | 0.777 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.379686e-01 | 0.623 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.379686e-01 | 0.623 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.379686e-01 | 0.623 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 2.379686e-01 | 0.623 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.379686e-01 | 0.623 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 2.379686e-01 | 0.623 | 0 | 0 |
| Impaired BRCA2 binding to SEM1 (DSS1) | R-HSA-9763198 | 2.379686e-01 | 0.623 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.379686e-01 | 0.623 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.379686e-01 | 0.623 | 0 | 0 |
| Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ) | R-HSA-5619088 | 2.379686e-01 | 0.623 | 0 | 0 |
| TWIK-related spinal cord K+ channel (TRESK) | R-HSA-1299344 | 2.379686e-01 | 0.623 | 0 | 0 |
| Impaired BRCA2 translocation to the nucleus | R-HSA-9709275 | 2.379686e-01 | 0.623 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.379686e-01 | 0.623 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 2.379686e-01 | 0.623 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.399577e-01 | 0.620 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 2.416673e-01 | 0.617 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 3.347976e-01 | 0.475 | 0 | 0 |
| Signaling by FGFR3 fusions in cancer | R-HSA-8853334 | 3.347976e-01 | 0.475 | 0 | 0 |
| t(4;14) translocations of FGFR3 | R-HSA-2033515 | 3.347976e-01 | 0.475 | 0 | 0 |
| Mitochondrial transcription initiation | R-HSA-163282 | 3.347976e-01 | 0.475 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 3.347976e-01 | 0.475 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 3.347976e-01 | 0.475 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.347976e-01 | 0.475 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 3.347976e-01 | 0.475 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 3.347976e-01 | 0.475 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 3.347976e-01 | 0.475 | 0 | 0 |
| Defective CD320 causes MMATC | R-HSA-3359485 | 3.347976e-01 | 0.475 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.347976e-01 | 0.475 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 3.347976e-01 | 0.475 | 0 | 0 |
| Defective PGM1 causes PGM1-CDG | R-HSA-5609974 | 3.347976e-01 | 0.475 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 3.347976e-01 | 0.475 | 0 | 0 |
| XAV939 stabilizes AXIN | R-HSA-5545619 | 3.347976e-01 | 0.475 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 3.347976e-01 | 0.475 | 0 | 0 |
| Intestinal infectious diseases | R-HSA-8942233 | 3.347976e-01 | 0.475 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.347976e-01 | 0.475 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 2.462652e-01 | 0.609 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 2.462652e-01 | 0.609 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.462652e-01 | 0.609 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 2.462652e-01 | 0.609 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 2.462652e-01 | 0.609 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 2.462652e-01 | 0.609 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 2.462652e-01 | 0.609 | 0 | 0 |
| Defective F9 activation | R-HSA-9673221 | 2.462652e-01 | 0.609 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 2.462652e-01 | 0.609 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 2.962168e-01 | 0.528 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 2.962168e-01 | 0.528 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 2.962168e-01 | 0.528 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 2.962168e-01 | 0.528 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 2.962168e-01 | 0.528 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 2.962168e-01 | 0.528 | 0 | 0 |
| Phase 1 - inactivation of fast Na+ channels | R-HSA-5576894 | 2.962168e-01 | 0.528 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 4.193277e-01 | 0.377 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 4.193277e-01 | 0.377 | 0 | 0 |
| Essential pentosuria | R-HSA-5662853 | 4.193277e-01 | 0.377 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 4.193277e-01 | 0.377 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 4.193277e-01 | 0.377 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 4.193277e-01 | 0.377 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 4.193277e-01 | 0.377 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 2.603684e-01 | 0.584 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 2.603684e-01 | 0.584 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 3.456477e-01 | 0.461 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 2.968768e-01 | 0.527 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 2.968768e-01 | 0.527 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 2.968768e-01 | 0.527 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 2.599538e-01 | 0.585 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 2.599538e-01 | 0.585 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 2.599538e-01 | 0.585 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 2.599538e-01 | 0.585 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.551521e-01 | 0.593 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 2.897322e-01 | 0.538 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 2.897322e-01 | 0.538 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 3.336477e-01 | 0.477 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 3.336477e-01 | 0.477 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 3.336477e-01 | 0.477 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 3.336477e-01 | 0.477 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 3.336477e-01 | 0.477 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 3.938841e-01 | 0.405 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 3.938841e-01 | 0.405 | 0 | 0 |
| PTK6 Expression | R-HSA-8849473 | 3.938841e-01 | 0.405 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 3.938841e-01 | 0.405 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 3.938841e-01 | 0.405 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 3.199382e-01 | 0.495 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 3.199382e-01 | 0.495 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 3.199382e-01 | 0.495 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 2.712396e-01 | 0.567 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 2.712396e-01 | 0.567 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 3.703311e-01 | 0.431 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 3.703311e-01 | 0.431 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 3.703311e-01 | 0.431 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 3.066791e-01 | 0.513 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 2.942288e-01 | 0.531 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 3.503595e-01 | 0.455 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 3.503595e-01 | 0.455 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 4.404318e-01 | 0.356 | 0 | 0 |
| FGFR1b ligand binding and activation | R-HSA-190370 | 4.404318e-01 | 0.356 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 4.404318e-01 | 0.356 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 2.442066e-01 | 0.612 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 2.826029e-01 | 0.549 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 3.329996e-01 | 0.478 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 3.329996e-01 | 0.478 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 3.175830e-01 | 0.498 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 4.066229e-01 | 0.391 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 3.036750e-01 | 0.518 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 2.909807e-01 | 0.536 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 2.909807e-01 | 0.536 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 3.595072e-01 | 0.444 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 3.412022e-01 | 0.467 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 3.105404e-01 | 0.508 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 3.105404e-01 | 0.508 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 3.105404e-01 | 0.508 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 3.105404e-01 | 0.508 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 3.022708e-01 | 0.520 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 3.156686e-01 | 0.501 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 3.466504e-01 | 0.460 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 3.466504e-01 | 0.460 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 3.466504e-01 | 0.460 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 3.649892e-01 | 0.438 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 4.422634e-01 | 0.354 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 4.422634e-01 | 0.354 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR3 | R-HSA-5654227 | 4.422634e-01 | 0.354 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 4.422634e-01 | 0.354 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 4.849411e-01 | 0.314 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 4.849411e-01 | 0.314 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 4.849411e-01 | 0.314 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 4.849411e-01 | 0.314 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 3.195682e-01 | 0.495 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 3.684050e-01 | 0.434 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 3.888501e-01 | 0.410 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 3.888501e-01 | 0.410 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 3.888501e-01 | 0.410 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 3.116741e-01 | 0.506 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.900995e-01 | 0.537 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 4.410287e-01 | 0.356 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 2.712605e-01 | 0.567 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.902412e-01 | 0.409 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 2.828852e-01 | 0.548 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 4.770358e-01 | 0.321 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 4.770358e-01 | 0.321 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 4.770358e-01 | 0.321 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 3.425964e-01 | 0.465 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 4.364395e-01 | 0.360 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 4.705116e-01 | 0.327 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 4.649293e-01 | 0.333 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 3.707801e-01 | 0.431 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 4.833146e-01 | 0.316 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 4.539256e-01 | 0.343 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 4.579208e-01 | 0.339 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 4.644836e-01 | 0.333 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 3.191100e-01 | 0.496 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 3.191100e-01 | 0.496 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 2.670991e-01 | 0.573 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 3.503789e-01 | 0.455 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 2.853588e-01 | 0.545 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 2.599538e-01 | 0.585 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 3.073487e-01 | 0.512 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 4.238224e-01 | 0.373 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 2.603684e-01 | 0.584 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 4.066229e-01 | 0.391 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 4.262732e-01 | 0.370 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 4.797835e-01 | 0.319 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 3.994211e-01 | 0.399 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 3.520921e-01 | 0.453 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 4.797835e-01 | 0.319 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 2.755912e-01 | 0.560 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 2.599538e-01 | 0.585 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.739994e-01 | 0.562 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 4.417602e-01 | 0.355 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.603684e-01 | 0.584 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 2.603684e-01 | 0.584 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 2.968768e-01 | 0.527 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 2.717394e-01 | 0.566 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 3.649892e-01 | 0.438 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 3.503789e-01 | 0.455 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 3.807990e-01 | 0.419 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 2.442066e-01 | 0.612 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 4.200001e-01 | 0.377 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 2.962168e-01 | 0.528 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 2.603684e-01 | 0.584 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 2.603684e-01 | 0.584 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 3.703311e-01 | 0.431 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 2.520245e-01 | 0.599 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 3.707801e-01 | 0.431 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 4.600039e-01 | 0.337 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 4.555616e-01 | 0.341 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 2.583391e-01 | 0.588 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 2.968631e-01 | 0.527 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 4.404318e-01 | 0.356 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 4.410287e-01 | 0.356 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 3.684050e-01 | 0.434 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 3.456477e-01 | 0.461 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 3.703311e-01 | 0.431 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 3.595072e-01 | 0.444 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.693337e-01 | 0.570 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 2.919063e-01 | 0.535 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 2.826029e-01 | 0.549 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 3.968181e-01 | 0.401 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 2.712396e-01 | 0.567 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.487168e-01 | 0.604 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 3.703311e-01 | 0.431 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 3.329996e-01 | 0.478 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 3.250492e-01 | 0.488 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 4.770358e-01 | 0.321 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 4.770358e-01 | 0.321 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 4.388918e-01 | 0.358 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 3.727792e-01 | 0.429 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 2.487168e-01 | 0.604 | 0 | 0 |
| Transcription from mitochondrial promoters | R-HSA-75944 | 4.193277e-01 | 0.377 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 3.199382e-01 | 0.495 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 2.942288e-01 | 0.531 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 4.404318e-01 | 0.356 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 2.826029e-01 | 0.549 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 3.250492e-01 | 0.488 | 0 | 0 |
| FGFR3 ligand binding and activation | R-HSA-190239 | 4.770358e-01 | 0.321 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 4.770358e-01 | 0.321 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 4.120897e-01 | 0.385 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 4.364395e-01 | 0.360 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 4.600039e-01 | 0.337 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 3.907869e-01 | 0.408 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 3.089359e-01 | 0.510 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 3.412022e-01 | 0.467 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 4.833146e-01 | 0.316 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 2.712396e-01 | 0.567 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 4.110763e-01 | 0.386 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 4.066229e-01 | 0.391 | 0 | 0 |
| S Phase | R-HSA-69242 | 4.078533e-01 | 0.389 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 3.045781e-01 | 0.516 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 3.498311e-01 | 0.456 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 2.603684e-01 | 0.584 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 3.456477e-01 | 0.461 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 2.897322e-01 | 0.538 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 3.938841e-01 | 0.405 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 4.422634e-01 | 0.354 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 4.364395e-01 | 0.360 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 4.705116e-01 | 0.327 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 2.528754e-01 | 0.597 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 3.860718e-01 | 0.413 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 2.487168e-01 | 0.604 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 4.338841e-01 | 0.363 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 2.712396e-01 | 0.567 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 3.303595e-01 | 0.481 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 4.422634e-01 | 0.354 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 4.849411e-01 | 0.314 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 4.364395e-01 | 0.360 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 4.600039e-01 | 0.337 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 2.599538e-01 | 0.585 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 3.303595e-01 | 0.481 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 3.195682e-01 | 0.495 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 3.968181e-01 | 0.401 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 4.214390e-01 | 0.375 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 3.271407e-01 | 0.485 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 3.347976e-01 | 0.475 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 3.347976e-01 | 0.475 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.462652e-01 | 0.609 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 4.193277e-01 | 0.377 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 4.193277e-01 | 0.377 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 4.193277e-01 | 0.377 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 4.193277e-01 | 0.377 | 0 | 0 |
| Influenza Virus Induced Apoptosis | R-HSA-168277 | 4.193277e-01 | 0.377 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 3.456477e-01 | 0.461 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 2.897322e-01 | 0.538 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 3.938841e-01 | 0.405 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.404318e-01 | 0.356 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 4.404318e-01 | 0.356 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 4.404318e-01 | 0.356 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 2.442066e-01 | 0.612 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 3.175830e-01 | 0.498 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 4.066229e-01 | 0.391 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 2.635556e-01 | 0.579 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 4.849411e-01 | 0.314 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 4.388918e-01 | 0.358 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 4.120897e-01 | 0.385 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 4.083364e-01 | 0.389 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 3.869346e-01 | 0.412 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 4.627993e-01 | 0.335 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 4.422634e-01 | 0.354 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 4.035337e-01 | 0.394 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.770358e-01 | 0.321 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 4.555616e-01 | 0.341 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 4.213400e-01 | 0.375 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.822619e-01 | 0.549 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 2.968768e-01 | 0.527 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 2.968768e-01 | 0.527 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 4.770358e-01 | 0.321 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 3.907869e-01 | 0.408 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 4.543108e-01 | 0.343 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 4.410287e-01 | 0.356 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 4.441833e-01 | 0.352 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 2.962168e-01 | 0.528 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 2.962168e-01 | 0.528 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 2.599538e-01 | 0.585 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 2.551521e-01 | 0.593 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 4.849411e-01 | 0.314 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 4.600039e-01 | 0.337 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 3.329996e-01 | 0.478 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 2.583391e-01 | 0.588 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 3.066791e-01 | 0.513 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 4.663075e-01 | 0.331 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 3.550846e-01 | 0.450 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 4.121350e-01 | 0.385 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 2.806826e-01 | 0.552 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 3.703311e-01 | 0.431 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 2.973414e-01 | 0.527 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in invasion | R-HSA-9854909 | 2.462652e-01 | 0.609 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 2.962168e-01 | 0.528 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 2.968768e-01 | 0.527 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 4.422634e-01 | 0.354 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 4.849411e-01 | 0.314 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 3.860718e-01 | 0.413 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 4.600039e-01 | 0.337 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 3.456477e-01 | 0.461 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 4.833146e-01 | 0.316 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 2.551521e-01 | 0.593 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 4.770358e-01 | 0.321 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 4.125712e-01 | 0.385 | 0 | 0 |
| Co-inhibition by BTLA | R-HSA-9927353 | 2.462652e-01 | 0.609 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 4.193277e-01 | 0.377 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 3.938841e-01 | 0.405 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 3.938841e-01 | 0.405 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 3.938841e-01 | 0.405 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 3.703311e-01 | 0.431 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 4.404318e-01 | 0.356 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 4.066229e-01 | 0.391 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 4.849411e-01 | 0.314 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 4.364395e-01 | 0.360 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 2.712396e-01 | 0.567 | 0 | 0 |
| P2Y receptors | R-HSA-417957 | 4.422634e-01 | 0.354 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 2.962168e-01 | 0.528 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 3.938841e-01 | 0.405 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 4.404318e-01 | 0.356 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 4.404318e-01 | 0.356 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 4.849411e-01 | 0.314 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 3.807990e-01 | 0.419 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 3.860718e-01 | 0.413 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 2.968768e-01 | 0.527 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 3.329996e-01 | 0.478 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 3.807990e-01 | 0.419 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 4.869732e-01 | 0.312 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 4.870863e-01 | 0.312 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 4.894950e-01 | 0.310 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 4.905893e-01 | 0.309 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 4.905893e-01 | 0.309 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 4.914231e-01 | 0.309 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 4.914231e-01 | 0.309 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 4.915575e-01 | 0.308 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 4.931205e-01 | 0.307 | 0 | 0 |
| Defective GCLC causes HAGGSD | R-HSA-5578999 | 4.931205e-01 | 0.307 | 0 | 0 |
| Defective MAOA causes BRUNS | R-HSA-5579012 | 4.931205e-01 | 0.307 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.931205e-01 | 0.307 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 4.931205e-01 | 0.307 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 4.931205e-01 | 0.307 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.931205e-01 | 0.307 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 4.931205e-01 | 0.307 | 0 | 0 |
| Activation of BMF and translocation to mitochondria | R-HSA-139910 | 4.931205e-01 | 0.307 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 4.931205e-01 | 0.307 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 4.931205e-01 | 0.307 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 4.967645e-01 | 0.304 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 4.983323e-01 | 0.302 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 4.983323e-01 | 0.302 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 4.993984e-01 | 0.302 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 4.993984e-01 | 0.302 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 4.993984e-01 | 0.302 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 5.021936e-01 | 0.299 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 5.063039e-01 | 0.296 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 5.082399e-01 | 0.294 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 5.107628e-01 | 0.292 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 5.107628e-01 | 0.292 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 5.107628e-01 | 0.292 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 5.107628e-01 | 0.292 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 5.110893e-01 | 0.292 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 5.110893e-01 | 0.292 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 5.128123e-01 | 0.290 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 5.148710e-01 | 0.288 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 5.156192e-01 | 0.288 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 5.157869e-01 | 0.288 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 5.205727e-01 | 0.284 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 5.222265e-01 | 0.282 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 5.271785e-01 | 0.278 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 5.271785e-01 | 0.278 | 0 | 0 |
| Arachidonate production from DAG | R-HSA-426048 | 5.271785e-01 | 0.278 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 5.271785e-01 | 0.278 | 0 | 0 |
| Defective factor IX causes hemophilia B | R-HSA-9668250 | 5.271785e-01 | 0.278 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 5.271785e-01 | 0.278 | 0 | 0 |
| Metal sequestration by antimicrobial proteins | R-HSA-6799990 | 5.271785e-01 | 0.278 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 5.275802e-01 | 0.278 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 5.275802e-01 | 0.278 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 5.275802e-01 | 0.278 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 5.275802e-01 | 0.278 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 5.275802e-01 | 0.278 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 5.316681e-01 | 0.274 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 5.369306e-01 | 0.270 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 5.369306e-01 | 0.270 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 5.403562e-01 | 0.267 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 5.404473e-01 | 0.267 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 5.404473e-01 | 0.267 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 5.433037e-01 | 0.265 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 5.433037e-01 | 0.265 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 5.433037e-01 | 0.265 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 5.433037e-01 | 0.265 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 5.433037e-01 | 0.265 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 5.496198e-01 | 0.260 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 5.497577e-01 | 0.260 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 5.545637e-01 | 0.256 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 5.549650e-01 | 0.256 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 5.549650e-01 | 0.256 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 5.575393e-01 | 0.254 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 5.575393e-01 | 0.254 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.575393e-01 | 0.254 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 5.575393e-01 | 0.254 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 5.575393e-01 | 0.254 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 5.575393e-01 | 0.254 | 0 | 0 |
| Alanine metabolism | R-HSA-8964540 | 5.575393e-01 | 0.254 | 0 | 0 |
| Electric Transmission Across Gap Junctions | R-HSA-112303 | 5.575393e-01 | 0.254 | 0 | 0 |
| Transmission across Electrical Synapses | R-HSA-112307 | 5.575393e-01 | 0.254 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 5.575393e-01 | 0.254 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 5.575393e-01 | 0.254 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.575393e-01 | 0.254 | 0 | 0 |
| Interleukin-38 signaling | R-HSA-9007892 | 5.575393e-01 | 0.254 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 5.576208e-01 | 0.254 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 5.582221e-01 | 0.253 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 5.582221e-01 | 0.253 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 5.645051e-01 | 0.248 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 5.670027e-01 | 0.246 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 5.670027e-01 | 0.246 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 5.670027e-01 | 0.246 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 5.670027e-01 | 0.246 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 5.684125e-01 | 0.245 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 5.701973e-01 | 0.244 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 5.745507e-01 | 0.241 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 5.745507e-01 | 0.241 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 5.780358e-01 | 0.238 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 5.801313e-01 | 0.236 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 5.801313e-01 | 0.236 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 5.814769e-01 | 0.235 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 5.814769e-01 | 0.235 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 5.841092e-01 | 0.234 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 5.868476e-01 | 0.231 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 5.879045e-01 | 0.231 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 5.919044e-01 | 0.228 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 5.939109e-01 | 0.226 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 5.947641e-01 | 0.226 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 5.958604e-01 | 0.225 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 5.988441e-01 | 0.223 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 5.988548e-01 | 0.223 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 5.988548e-01 | 0.223 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 5.995583e-01 | 0.222 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 6.005189e-01 | 0.221 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 6.043448e-01 | 0.219 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 6.043448e-01 | 0.219 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 6.043448e-01 | 0.219 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 6.043448e-01 | 0.219 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 6.044252e-01 | 0.219 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 6.044252e-01 | 0.219 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 6.044252e-01 | 0.219 | 0 | 0 |
| Nucleotide-like (purinergic) receptors | R-HSA-418038 | 6.044252e-01 | 0.219 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 6.048973e-01 | 0.218 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 6.070551e-01 | 0.217 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 6.070551e-01 | 0.217 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 6.080359e-01 | 0.216 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 6.099683e-01 | 0.215 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 6.102747e-01 | 0.214 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 6.105792e-01 | 0.214 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 6.105987e-01 | 0.214 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 6.105987e-01 | 0.214 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 6.137745e-01 | 0.212 | 0 | 0 |
| Defective CYP17A1 causes AH5 | R-HSA-5579028 | 6.137745e-01 | 0.212 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 6.137745e-01 | 0.212 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 6.137745e-01 | 0.212 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 6.137745e-01 | 0.212 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 6.137745e-01 | 0.212 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 6.137745e-01 | 0.212 | 0 | 0 |
| Phosphorylation and nuclear translocation of BMAL1 (ARNTL) and CLOCK | R-HSA-9931529 | 6.137745e-01 | 0.212 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 6.137745e-01 | 0.212 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 6.137745e-01 | 0.212 | 0 | 0 |
| Activation of C3 and C5 | R-HSA-174577 | 6.137745e-01 | 0.212 | 0 | 0 |
| PTK6 Activates STAT3 | R-HSA-8849474 | 6.137745e-01 | 0.212 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 6.137745e-01 | 0.212 | 0 | 0 |
| Inositol transporters | R-HSA-429593 | 6.137745e-01 | 0.212 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 6.137745e-01 | 0.212 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 6.137745e-01 | 0.212 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 6.137745e-01 | 0.212 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 6.137745e-01 | 0.212 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 6.144946e-01 | 0.211 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 6.144946e-01 | 0.211 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 6.144946e-01 | 0.211 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 6.181250e-01 | 0.209 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 6.185099e-01 | 0.209 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 6.225367e-01 | 0.206 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 6.243438e-01 | 0.205 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 6.243438e-01 | 0.205 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 6.243438e-01 | 0.205 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 6.265222e-01 | 0.203 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 6.281481e-01 | 0.202 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 6.322709e-01 | 0.199 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 6.328743e-01 | 0.199 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 6.328743e-01 | 0.199 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 6.328743e-01 | 0.199 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 6.328743e-01 | 0.199 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 6.328743e-01 | 0.199 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 6.328743e-01 | 0.199 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 6.328743e-01 | 0.199 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 6.344800e-01 | 0.198 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 6.369603e-01 | 0.196 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 6.391924e-01 | 0.194 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 6.391924e-01 | 0.194 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 6.391924e-01 | 0.194 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 6.391924e-01 | 0.194 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 6.391924e-01 | 0.194 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 6.391924e-01 | 0.194 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 6.391924e-01 | 0.194 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 6.391924e-01 | 0.194 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 6.391924e-01 | 0.194 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 6.391924e-01 | 0.194 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 6.391924e-01 | 0.194 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 6.397442e-01 | 0.194 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 6.397442e-01 | 0.194 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 6.397442e-01 | 0.194 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 6.426960e-01 | 0.192 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 6.438544e-01 | 0.191 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 6.473046e-01 | 0.189 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 6.537263e-01 | 0.185 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 6.537263e-01 | 0.185 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 6.538413e-01 | 0.185 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 6.538413e-01 | 0.185 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 6.549823e-01 | 0.184 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 6.552360e-01 | 0.184 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 6.552360e-01 | 0.184 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 6.552360e-01 | 0.184 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 6.555229e-01 | 0.183 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 6.580367e-01 | 0.182 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 6.598680e-01 | 0.181 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 6.610592e-01 | 0.180 | 0 | 0 |
| Nef Mediated CD8 Down-regulation | R-HSA-182218 | 6.628652e-01 | 0.179 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.628652e-01 | 0.179 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.628652e-01 | 0.179 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.628652e-01 | 0.179 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 6.628652e-01 | 0.179 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 6.628652e-01 | 0.179 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 6.628652e-01 | 0.179 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 6.628652e-01 | 0.179 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 6.628652e-01 | 0.179 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 6.628652e-01 | 0.179 | 0 | 0 |
| Formation of the Editosome | R-HSA-75094 | 6.628652e-01 | 0.179 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 6.628652e-01 | 0.179 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 6.628652e-01 | 0.179 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.628652e-01 | 0.179 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 6.628652e-01 | 0.179 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.628652e-01 | 0.179 | 0 | 0 |
| Acetylcholine inhibits contraction of outer hair cells | R-HSA-9667769 | 6.628652e-01 | 0.179 | 0 | 0 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 6.628652e-01 | 0.179 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 6.628652e-01 | 0.179 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 6.628652e-01 | 0.179 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.628652e-01 | 0.179 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 6.628652e-01 | 0.179 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 6.715764e-01 | 0.173 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 6.715764e-01 | 0.173 | 0 | 0 |
| FGFR1c ligand binding and activation | R-HSA-190373 | 6.715764e-01 | 0.173 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 6.715764e-01 | 0.173 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 6.715764e-01 | 0.173 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 6.724702e-01 | 0.172 | 0 | 0 |
| Immune System | R-HSA-168256 | 6.724780e-01 | 0.172 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 6.727916e-01 | 0.172 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 6.752532e-01 | 0.171 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.769189e-01 | 0.169 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 6.769709e-01 | 0.169 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 6.777821e-01 | 0.169 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 6.777821e-01 | 0.169 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 6.777821e-01 | 0.169 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 6.777821e-01 | 0.169 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 6.782483e-01 | 0.169 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 6.853950e-01 | 0.164 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 6.853950e-01 | 0.164 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 6.886028e-01 | 0.162 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 6.894519e-01 | 0.161 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 6.981811e-01 | 0.156 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 6.992790e-01 | 0.155 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 6.992790e-01 | 0.155 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 7.015600e-01 | 0.154 | 0 | 0 |
| Synthesis of IPs in the nucleus | R-HSA-1855191 | 7.015600e-01 | 0.154 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 7.015600e-01 | 0.154 | 0 | 0 |
| FGFR3c ligand binding and activation | R-HSA-190372 | 7.015600e-01 | 0.154 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 7.015600e-01 | 0.154 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 7.015600e-01 | 0.154 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 7.015600e-01 | 0.154 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 7.015600e-01 | 0.154 | 0 | 0 |
| Malate-aspartate shuttle | R-HSA-9856872 | 7.015600e-01 | 0.154 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 7.015600e-01 | 0.154 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 7.020082e-01 | 0.154 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 7.033010e-01 | 0.153 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 7.039304e-01 | 0.152 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 7.039790e-01 | 0.152 | 0 | 0 |
| Chylomicron clearance | R-HSA-8964026 | 7.057188e-01 | 0.151 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 7.057188e-01 | 0.151 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 7.057188e-01 | 0.151 | 0 | 0 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors | R-HSA-629587 | 7.057188e-01 | 0.151 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 7.057188e-01 | 0.151 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 7.057188e-01 | 0.151 | 0 | 0 |
| Hydrolysis of LPE | R-HSA-1483152 | 7.057188e-01 | 0.151 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 7.057188e-01 | 0.151 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 7.057188e-01 | 0.151 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 7.057188e-01 | 0.151 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 7.057188e-01 | 0.151 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 7.057188e-01 | 0.151 | 0 | 0 |
| Leukotriene receptors | R-HSA-391906 | 7.057188e-01 | 0.151 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 7.079994e-01 | 0.150 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 7.079994e-01 | 0.150 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 7.079994e-01 | 0.150 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 7.079994e-01 | 0.150 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 7.082339e-01 | 0.150 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 7.094606e-01 | 0.149 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 7.094606e-01 | 0.149 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 7.094606e-01 | 0.149 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 7.187484e-01 | 0.143 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 7.197236e-01 | 0.143 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 7.210589e-01 | 0.142 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 7.247066e-01 | 0.140 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 7.247066e-01 | 0.140 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 7.292300e-01 | 0.137 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 7.292300e-01 | 0.137 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 7.292300e-01 | 0.137 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 7.292300e-01 | 0.137 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 7.310084e-01 | 0.136 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 7.320838e-01 | 0.135 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 7.320838e-01 | 0.135 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 7.320838e-01 | 0.135 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.320838e-01 | 0.135 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 7.330697e-01 | 0.135 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 7.361702e-01 | 0.133 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 7.391211e-01 | 0.131 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 7.391211e-01 | 0.131 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 7.407331e-01 | 0.130 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 7.431274e-01 | 0.129 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 7.431274e-01 | 0.129 | 0 | 0 |
| FGFR3b ligand binding and activation | R-HSA-190371 | 7.431274e-01 | 0.129 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis | R-HSA-9632974 | 7.431274e-01 | 0.129 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 7.431274e-01 | 0.129 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 7.431274e-01 | 0.129 | 0 | 0 |
| mRNA Editing: C to U Conversion | R-HSA-72200 | 7.431274e-01 | 0.129 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 7.431274e-01 | 0.129 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 7.431274e-01 | 0.129 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 7.431274e-01 | 0.129 | 0 | 0 |
| Synthesis of PIPs in the nucleus | R-HSA-8847453 | 7.431274e-01 | 0.129 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 7.431274e-01 | 0.129 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 7.431274e-01 | 0.129 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.431274e-01 | 0.129 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 7.431274e-01 | 0.129 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 7.431274e-01 | 0.129 | 0 | 0 |
| Maturation of replicase proteins | R-HSA-9694301 | 7.431274e-01 | 0.129 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 7.441922e-01 | 0.128 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 7.441922e-01 | 0.128 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 7.446053e-01 | 0.128 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 7.474420e-01 | 0.126 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 7.483135e-01 | 0.126 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 7.507010e-01 | 0.125 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 7.518473e-01 | 0.124 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 7.532945e-01 | 0.123 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 7.532945e-01 | 0.123 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 7.532945e-01 | 0.123 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.532945e-01 | 0.123 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 7.532945e-01 | 0.123 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 7.546902e-01 | 0.122 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 7.546902e-01 | 0.122 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 7.546902e-01 | 0.122 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 7.546902e-01 | 0.122 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 7.546902e-01 | 0.122 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 7.546902e-01 | 0.122 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 7.546902e-01 | 0.122 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 7.546902e-01 | 0.122 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 7.546902e-01 | 0.122 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 7.556620e-01 | 0.122 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 7.560796e-01 | 0.121 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 7.560796e-01 | 0.121 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 7.569262e-01 | 0.121 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 7.574835e-01 | 0.121 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 7.574835e-01 | 0.121 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 7.574835e-01 | 0.121 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 7.690892e-01 | 0.114 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 7.708499e-01 | 0.113 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 7.731318e-01 | 0.112 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.731318e-01 | 0.112 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 7.757826e-01 | 0.110 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 7.757826e-01 | 0.110 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.757826e-01 | 0.110 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 7.757826e-01 | 0.110 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 7.757826e-01 | 0.110 | 0 | 0 |
| Highly calcium permeable nicotinic acetylcholine receptors | R-HSA-629597 | 7.757826e-01 | 0.110 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 7.757826e-01 | 0.110 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 7.757826e-01 | 0.110 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 7.757826e-01 | 0.110 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 7.757826e-01 | 0.110 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 7.757826e-01 | 0.110 | 0 | 0 |
| Fructose biosynthesis | R-HSA-5652227 | 7.757826e-01 | 0.110 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 7.757826e-01 | 0.110 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 7.757826e-01 | 0.110 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 7.757826e-01 | 0.110 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 7.757826e-01 | 0.110 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 7.757826e-01 | 0.110 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 7.757826e-01 | 0.110 | 0 | 0 |
| Alpha-defensins | R-HSA-1462054 | 7.757826e-01 | 0.110 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 7.780551e-01 | 0.109 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 7.780551e-01 | 0.109 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 7.780551e-01 | 0.109 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 7.780551e-01 | 0.109 | 0 | 0 |
| Formation of xylulose-5-phosphate | R-HSA-5661270 | 7.780551e-01 | 0.109 | 0 | 0 |
| Galactose catabolism | R-HSA-70370 | 7.780551e-01 | 0.109 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 7.780551e-01 | 0.109 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 7.791968e-01 | 0.108 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 7.791968e-01 | 0.108 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 7.806863e-01 | 0.108 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 7.847516e-01 | 0.105 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 7.887730e-01 | 0.103 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 7.908285e-01 | 0.102 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 7.910816e-01 | 0.102 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 7.915898e-01 | 0.101 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 7.915898e-01 | 0.101 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 7.916419e-01 | 0.101 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 7.924338e-01 | 0.101 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 7.936213e-01 | 0.100 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 7.938774e-01 | 0.100 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 7.970966e-01 | 0.098 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 7.980935e-01 | 0.098 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 7.994458e-01 | 0.097 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 7.994458e-01 | 0.097 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 7.994458e-01 | 0.097 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 8.030667e-01 | 0.095 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 8.033800e-01 | 0.095 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 8.042881e-01 | 0.095 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 8.042881e-01 | 0.095 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 8.042881e-01 | 0.095 | 0 | 0 |
| Enzymatic degradation of Dopamine by monoamine oxidase | R-HSA-379398 | 8.042881e-01 | 0.095 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 8.042881e-01 | 0.095 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 8.042881e-01 | 0.095 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 8.042881e-01 | 0.095 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 8.042881e-01 | 0.095 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 8.042881e-01 | 0.095 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 8.065647e-01 | 0.093 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 8.065647e-01 | 0.093 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.065647e-01 | 0.093 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 8.084043e-01 | 0.092 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 8.088762e-01 | 0.092 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 8.107876e-01 | 0.091 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 8.138888e-01 | 0.089 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 8.146457e-01 | 0.089 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 8.189867e-01 | 0.087 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 8.189867e-01 | 0.087 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 8.189867e-01 | 0.087 | 0 | 0 |
| FGFR1 ligand binding and activation | R-HSA-190242 | 8.189867e-01 | 0.087 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 8.189867e-01 | 0.087 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 8.189867e-01 | 0.087 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 8.189867e-01 | 0.087 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 8.209291e-01 | 0.086 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 8.228475e-01 | 0.085 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 8.228475e-01 | 0.085 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 8.228475e-01 | 0.085 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 8.239663e-01 | 0.084 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 8.248079e-01 | 0.084 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 8.248902e-01 | 0.084 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 8.248902e-01 | 0.084 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 8.248902e-01 | 0.084 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 8.248902e-01 | 0.084 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 8.258874e-01 | 0.083 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.258874e-01 | 0.083 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 8.288202e-01 | 0.082 | 0 | 0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | R-HSA-629594 | 8.291710e-01 | 0.081 | 0 | 0 |
| TET1,2,3 and TDG demethylate DNA | R-HSA-5221030 | 8.291710e-01 | 0.081 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 8.291710e-01 | 0.081 | 0 | 0 |
| Ion influx/efflux at host-pathogen interface | R-HSA-6803544 | 8.291710e-01 | 0.081 | 0 | 0 |
| Metabolism of serotonin | R-HSA-380612 | 8.291710e-01 | 0.081 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 8.291710e-01 | 0.081 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 8.291710e-01 | 0.081 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 8.291710e-01 | 0.081 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 8.291710e-01 | 0.081 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 8.291710e-01 | 0.081 | 0 | 0 |
| Enzymatic degradation of dopamine by COMT | R-HSA-379397 | 8.291710e-01 | 0.081 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 8.291710e-01 | 0.081 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 8.291710e-01 | 0.081 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 8.333411e-01 | 0.079 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 8.334204e-01 | 0.079 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 8.342887e-01 | 0.079 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 8.342887e-01 | 0.079 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 8.345582e-01 | 0.079 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 8.345582e-01 | 0.079 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 8.345582e-01 | 0.079 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 8.364921e-01 | 0.078 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 8.364921e-01 | 0.078 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 8.368022e-01 | 0.077 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 8.368022e-01 | 0.077 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 8.368022e-01 | 0.077 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 8.368022e-01 | 0.077 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.368022e-01 | 0.077 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 8.397421e-01 | 0.076 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 8.472358e-01 | 0.072 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 8.472358e-01 | 0.072 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 8.472358e-01 | 0.072 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 8.488666e-01 | 0.071 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 8.491957e-01 | 0.071 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 8.508916e-01 | 0.070 | 0 | 0 |
| FGFR2b ligand binding and activation | R-HSA-190377 | 8.508916e-01 | 0.070 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 8.508916e-01 | 0.070 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 8.508916e-01 | 0.070 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 8.508916e-01 | 0.070 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 8.508916e-01 | 0.070 | 0 | 0 |
| Cholesterol biosynthesis via desmosterol | R-HSA-6807047 | 8.508916e-01 | 0.070 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 8.508916e-01 | 0.070 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 8.508916e-01 | 0.070 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 8.508916e-01 | 0.070 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 8.508916e-01 | 0.070 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 8.515094e-01 | 0.070 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 8.530152e-01 | 0.069 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 8.530152e-01 | 0.069 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 8.530152e-01 | 0.069 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 8.530152e-01 | 0.069 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 8.530152e-01 | 0.069 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 8.534915e-01 | 0.069 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.534915e-01 | 0.069 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 8.534915e-01 | 0.069 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 8.549830e-01 | 0.068 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 8.560542e-01 | 0.067 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 8.560542e-01 | 0.067 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 8.578393e-01 | 0.067 | 0 | 0 |
| Depurination | R-HSA-73927 | 8.590822e-01 | 0.066 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 8.590822e-01 | 0.066 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.637074e-01 | 0.064 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 8.641050e-01 | 0.063 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 8.641174e-01 | 0.063 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 8.661987e-01 | 0.062 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 8.661987e-01 | 0.062 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 8.664058e-01 | 0.062 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 8.664058e-01 | 0.062 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 8.664724e-01 | 0.062 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 8.664724e-01 | 0.062 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 8.677449e-01 | 0.062 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 8.677449e-01 | 0.062 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 8.677449e-01 | 0.062 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 8.677449e-01 | 0.062 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 8.677449e-01 | 0.062 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 8.677449e-01 | 0.062 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 8.695101e-01 | 0.061 | 0 | 0 |
| Presynaptic nicotinic acetylcholine receptors | R-HSA-622323 | 8.698515e-01 | 0.061 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 8.698515e-01 | 0.061 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 8.698515e-01 | 0.061 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 8.698515e-01 | 0.061 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 8.698515e-01 | 0.061 | 0 | 0 |
| Signaling by activated point mutants of FGFR1 | R-HSA-1839122 | 8.698515e-01 | 0.061 | 0 | 0 |
| Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB | R-HSA-141333 | 8.698515e-01 | 0.061 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 8.698515e-01 | 0.061 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.698515e-01 | 0.061 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 8.698515e-01 | 0.061 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 8.701353e-01 | 0.060 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 8.701353e-01 | 0.060 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 8.713292e-01 | 0.060 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 8.728686e-01 | 0.059 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 8.728686e-01 | 0.059 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 8.804329e-01 | 0.055 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 8.804329e-01 | 0.055 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 8.804329e-01 | 0.055 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 8.811065e-01 | 0.055 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 8.811065e-01 | 0.055 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 8.811065e-01 | 0.055 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 8.845364e-01 | 0.053 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 8.845364e-01 | 0.053 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 8.852313e-01 | 0.053 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 8.864016e-01 | 0.052 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.864016e-01 | 0.052 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 8.864016e-01 | 0.052 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 8.864016e-01 | 0.052 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 8.864016e-01 | 0.052 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 8.864016e-01 | 0.052 | 0 | 0 |
| Proline catabolism | R-HSA-70688 | 8.864016e-01 | 0.052 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.864016e-01 | 0.052 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 8.864016e-01 | 0.052 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 8.864016e-01 | 0.052 | 0 | 0 |
| Estrogen biosynthesis | R-HSA-193144 | 8.864016e-01 | 0.052 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.864016e-01 | 0.052 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 8.887269e-01 | 0.051 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 8.900135e-01 | 0.051 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 8.909555e-01 | 0.050 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.911300e-01 | 0.050 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 8.911300e-01 | 0.050 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 8.922081e-01 | 0.050 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 8.932096e-01 | 0.049 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 8.932096e-01 | 0.049 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 8.932096e-01 | 0.049 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 8.932096e-01 | 0.049 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 8.932096e-01 | 0.049 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.937596e-01 | 0.049 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 8.942898e-01 | 0.049 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 8.981663e-01 | 0.047 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 8.985878e-01 | 0.046 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 8.985878e-01 | 0.046 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 8.989150e-01 | 0.046 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 9.007364e-01 | 0.045 | 0 | 0 |
| Acetylcholine binding and downstream events | R-HSA-181431 | 9.008479e-01 | 0.045 | 0 | 0 |
| Postsynaptic nicotinic acetylcholine receptors | R-HSA-622327 | 9.008479e-01 | 0.045 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 9.008479e-01 | 0.045 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 9.008479e-01 | 0.045 | 0 | 0 |
| FGFR2c ligand binding and activation | R-HSA-190375 | 9.008479e-01 | 0.045 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 9.008479e-01 | 0.045 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 9.008479e-01 | 0.045 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 9.008479e-01 | 0.045 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 9.008479e-01 | 0.045 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 9.008479e-01 | 0.045 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 9.008479e-01 | 0.045 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 9.015066e-01 | 0.045 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.041581e-01 | 0.044 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 9.057574e-01 | 0.043 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 9.071749e-01 | 0.042 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.071749e-01 | 0.042 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.071749e-01 | 0.042 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 9.077974e-01 | 0.042 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.077974e-01 | 0.042 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.077974e-01 | 0.042 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 9.091833e-01 | 0.041 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 9.091833e-01 | 0.041 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 9.093361e-01 | 0.041 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 9.103182e-01 | 0.041 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 9.124852e-01 | 0.040 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 9.134578e-01 | 0.039 | 0 | 0 |
| Transport of fatty acids | R-HSA-804914 | 9.134578e-01 | 0.039 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 9.134578e-01 | 0.039 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 9.134578e-01 | 0.039 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 9.140499e-01 | 0.039 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 9.140499e-01 | 0.039 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.140499e-01 | 0.039 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.140499e-01 | 0.039 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.148300e-01 | 0.039 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.161327e-01 | 0.038 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 9.161763e-01 | 0.038 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 9.161763e-01 | 0.038 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 9.161763e-01 | 0.038 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.161763e-01 | 0.038 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 9.161763e-01 | 0.038 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.161763e-01 | 0.038 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 9.164117e-01 | 0.038 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.198147e-01 | 0.036 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 9.219163e-01 | 0.035 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 9.219163e-01 | 0.035 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 9.226091e-01 | 0.035 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.226091e-01 | 0.035 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 9.229767e-01 | 0.035 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 9.229767e-01 | 0.035 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 9.229767e-01 | 0.035 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 9.229767e-01 | 0.035 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.229767e-01 | 0.035 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 9.229767e-01 | 0.035 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 9.229767e-01 | 0.035 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 9.244647e-01 | 0.034 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 9.244647e-01 | 0.034 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 9.244647e-01 | 0.034 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 9.244647e-01 | 0.034 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 9.244647e-01 | 0.034 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 9.244647e-01 | 0.034 | 0 | 0 |
| Dopamine clearance from the synaptic cleft | R-HSA-379401 | 9.244647e-01 | 0.034 | 0 | 0 |
| Events associated with phagocytolytic activity of PMN cells | R-HSA-8941413 | 9.244647e-01 | 0.034 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 9.244647e-01 | 0.034 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 9.244647e-01 | 0.034 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 9.244647e-01 | 0.034 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 9.244647e-01 | 0.034 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.284684e-01 | 0.032 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 9.284684e-01 | 0.032 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 9.284684e-01 | 0.032 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 9.286382e-01 | 0.032 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 9.302221e-01 | 0.031 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 9.307473e-01 | 0.031 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 9.308844e-01 | 0.031 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 9.308844e-01 | 0.031 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 9.308844e-01 | 0.031 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.308844e-01 | 0.031 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 9.310238e-01 | 0.031 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 9.310238e-01 | 0.031 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.310238e-01 | 0.031 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.310238e-01 | 0.031 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.320746e-01 | 0.031 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.325903e-01 | 0.030 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 9.340722e-01 | 0.030 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 9.340722e-01 | 0.030 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 9.340722e-01 | 0.030 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 9.340722e-01 | 0.030 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 9.340722e-01 | 0.030 | 0 | 0 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 9.340722e-01 | 0.030 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 9.340722e-01 | 0.030 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.340722e-01 | 0.030 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.342451e-01 | 0.030 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 9.345200e-01 | 0.029 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 9.373116e-01 | 0.028 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.373116e-01 | 0.028 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.373116e-01 | 0.028 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 9.382706e-01 | 0.028 | 0 | 0 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane | R-HSA-83936 | 9.382706e-01 | 0.028 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 9.394541e-01 | 0.027 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 9.424582e-01 | 0.026 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 9.424582e-01 | 0.026 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 9.424582e-01 | 0.026 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 9.424582e-01 | 0.026 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 9.424582e-01 | 0.026 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 9.424582e-01 | 0.026 | 0 | 0 |
| Heme assimilation | R-HSA-9927020 | 9.424582e-01 | 0.026 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.424582e-01 | 0.026 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 9.431822e-01 | 0.025 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 9.447903e-01 | 0.025 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 9.452498e-01 | 0.024 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.476950e-01 | 0.023 | 0 | 0 |
| Phospholipase C-mediated cascade: FGFR1 | R-HSA-5654219 | 9.497779e-01 | 0.022 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 9.497779e-01 | 0.022 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 9.497779e-01 | 0.022 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 9.497779e-01 | 0.022 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 9.497779e-01 | 0.022 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 9.497779e-01 | 0.022 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 9.497779e-01 | 0.022 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.497800e-01 | 0.022 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.499885e-01 | 0.022 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 9.506508e-01 | 0.022 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.528016e-01 | 0.021 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.534217e-01 | 0.021 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 9.534217e-01 | 0.021 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 9.534945e-01 | 0.021 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 9.537446e-01 | 0.021 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.559141e-01 | 0.020 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.561669e-01 | 0.019 | 0 | 0 |
| Activated point mutants of FGFR2 | R-HSA-2033519 | 9.561669e-01 | 0.019 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.561669e-01 | 0.019 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 9.564344e-01 | 0.019 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 9.567696e-01 | 0.019 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.567696e-01 | 0.019 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.570565e-01 | 0.019 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.578687e-01 | 0.019 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 9.578687e-01 | 0.019 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.578687e-01 | 0.019 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.578806e-01 | 0.019 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.583541e-01 | 0.018 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 9.583541e-01 | 0.018 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.586987e-01 | 0.018 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 9.606374e-01 | 0.017 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.606374e-01 | 0.017 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.606374e-01 | 0.017 | 0 | 0 |
| Aspartate and asparagine metabolism | R-HSA-8963693 | 9.606374e-01 | 0.017 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 9.606996e-01 | 0.017 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 9.606996e-01 | 0.017 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 9.608577e-01 | 0.017 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 9.617434e-01 | 0.017 | 0 | 0 |
| Amine Oxidase reactions | R-HSA-140179 | 9.617434e-01 | 0.017 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 9.617434e-01 | 0.017 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 9.617434e-01 | 0.017 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 9.617434e-01 | 0.017 | 0 | 0 |
| HDL remodeling | R-HSA-8964058 | 9.617434e-01 | 0.017 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.619150e-01 | 0.017 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.619150e-01 | 0.017 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.620331e-01 | 0.017 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 9.620331e-01 | 0.017 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.645770e-01 | 0.016 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.648727e-01 | 0.016 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 9.650750e-01 | 0.015 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.655936e-01 | 0.015 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.655936e-01 | 0.015 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 9.658620e-01 | 0.015 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.660076e-01 | 0.015 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 9.666108e-01 | 0.015 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR2 | R-HSA-5654221 | 9.666108e-01 | 0.015 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 9.666108e-01 | 0.015 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 9.666108e-01 | 0.015 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.666108e-01 | 0.015 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.666108e-01 | 0.015 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 9.666108e-01 | 0.015 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.666108e-01 | 0.015 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.666108e-01 | 0.015 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 9.686679e-01 | 0.014 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.686679e-01 | 0.014 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 9.689351e-01 | 0.014 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.689351e-01 | 0.014 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 9.693162e-01 | 0.014 | 0 | 0 |
| FGFR2 ligand binding and activation | R-HSA-190241 | 9.708591e-01 | 0.013 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 9.708591e-01 | 0.013 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.708591e-01 | 0.013 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 9.708591e-01 | 0.013 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.712902e-01 | 0.013 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 9.719680e-01 | 0.012 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.719680e-01 | 0.012 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.720662e-01 | 0.012 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 9.720662e-01 | 0.012 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.720662e-01 | 0.012 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.720662e-01 | 0.012 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.725933e-01 | 0.012 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 9.738924e-01 | 0.011 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 9.745671e-01 | 0.011 | 0 | 0 |
| Androgen biosynthesis | R-HSA-193048 | 9.745671e-01 | 0.011 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.745671e-01 | 0.011 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 9.745671e-01 | 0.011 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 9.745671e-01 | 0.011 | 0 | 0 |
| Glucocorticoid biosynthesis | R-HSA-194002 | 9.745671e-01 | 0.011 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.745671e-01 | 0.011 | 0 | 0 |
| Ribavirin ADME | R-HSA-9755088 | 9.745671e-01 | 0.011 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.747187e-01 | 0.011 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 9.747187e-01 | 0.011 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.747187e-01 | 0.011 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 9.747187e-01 | 0.011 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 9.747187e-01 | 0.011 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 9.751073e-01 | 0.011 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.751073e-01 | 0.011 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 9.751073e-01 | 0.011 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 9.755326e-01 | 0.011 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.772117e-01 | 0.010 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.772117e-01 | 0.010 | 0 | 0 |
| Ethanol oxidation | R-HSA-71384 | 9.778035e-01 | 0.010 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.778035e-01 | 0.010 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.778270e-01 | 0.010 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 9.778270e-01 | 0.010 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 9.778270e-01 | 0.010 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.778270e-01 | 0.010 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 9.778270e-01 | 0.010 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 9.787945e-01 | 0.009 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.802578e-01 | 0.009 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 9.804524e-01 | 0.009 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 9.806282e-01 | 0.008 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 9.806282e-01 | 0.008 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.806282e-01 | 0.008 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.806282e-01 | 0.008 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 9.806282e-01 | 0.008 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.806282e-01 | 0.008 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.806282e-01 | 0.008 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 9.808267e-01 | 0.008 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.822597e-01 | 0.008 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.822597e-01 | 0.008 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.824292e-01 | 0.008 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.824292e-01 | 0.008 | 0 | 0 |
| CYP2E1 reactions | R-HSA-211999 | 9.830936e-01 | 0.007 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 9.830936e-01 | 0.007 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 9.830936e-01 | 0.007 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.830936e-01 | 0.007 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 9.830936e-01 | 0.007 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.833609e-01 | 0.007 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.837974e-01 | 0.007 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.840543e-01 | 0.007 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.843678e-01 | 0.007 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 9.852453e-01 | 0.006 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.852453e-01 | 0.006 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 9.852453e-01 | 0.006 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 9.852453e-01 | 0.006 | 0 | 0 |
| Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.852453e-01 | 0.006 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.852453e-01 | 0.006 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.860977e-01 | 0.006 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 9.860977e-01 | 0.006 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.860977e-01 | 0.006 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.860977e-01 | 0.006 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 9.871233e-01 | 0.006 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.871233e-01 | 0.006 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.871233e-01 | 0.006 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 9.875432e-01 | 0.005 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.876407e-01 | 0.005 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.876407e-01 | 0.005 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 9.876407e-01 | 0.005 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 9.887473e-01 | 0.005 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 9.887624e-01 | 0.005 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.887624e-01 | 0.005 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.887624e-01 | 0.005 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.887624e-01 | 0.005 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.887624e-01 | 0.005 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.887624e-01 | 0.005 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.890162e-01 | 0.005 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.900540e-01 | 0.004 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.901929e-01 | 0.004 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 9.902419e-01 | 0.004 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 9.902419e-01 | 0.004 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 9.902419e-01 | 0.004 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.902419e-01 | 0.004 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 9.903973e-01 | 0.004 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.906753e-01 | 0.004 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.906753e-01 | 0.004 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.911247e-01 | 0.004 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 9.912387e-01 | 0.004 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.913336e-01 | 0.004 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.914413e-01 | 0.004 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.914413e-01 | 0.004 | 0 | 0 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 9.914413e-01 | 0.004 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 9.914413e-01 | 0.004 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.915173e-01 | 0.004 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.918536e-01 | 0.004 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.919751e-01 | 0.003 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.921385e-01 | 0.003 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.921580e-01 | 0.003 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 9.921685e-01 | 0.003 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 9.923056e-01 | 0.003 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 9.925309e-01 | 0.003 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.931706e-01 | 0.003 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 9.934351e-01 | 0.003 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 9.934476e-01 | 0.003 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.934476e-01 | 0.003 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 9.934819e-01 | 0.003 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.939401e-01 | 0.003 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 9.941265e-01 | 0.003 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.941720e-01 | 0.003 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.946245e-01 | 0.002 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.946245e-01 | 0.002 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.949230e-01 | 0.002 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.949230e-01 | 0.002 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.950361e-01 | 0.002 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.950367e-01 | 0.002 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.956767e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.957735e-01 | 0.002 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.960796e-01 | 0.002 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.961981e-01 | 0.002 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 9.962198e-01 | 0.002 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.962198e-01 | 0.002 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.962198e-01 | 0.002 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.963857e-01 | 0.002 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.966056e-01 | 0.001 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.967396e-01 | 0.001 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.970591e-01 | 0.001 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.971320e-01 | 0.001 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.971765e-01 | 0.001 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.971765e-01 | 0.001 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.973923e-01 | 0.001 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.974881e-01 | 0.001 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.974881e-01 | 0.001 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.976689e-01 | 0.001 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.976934e-01 | 0.001 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.978080e-01 | 0.001 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.978080e-01 | 0.001 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.978183e-01 | 0.001 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.978183e-01 | 0.001 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.978183e-01 | 0.001 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.979168e-01 | 0.001 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.980872e-01 | 0.001 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.981190e-01 | 0.001 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.981925e-01 | 0.001 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.982087e-01 | 0.001 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 9.983309e-01 | 0.001 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 9.983309e-01 | 0.001 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.985159e-01 | 0.001 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.985159e-01 | 0.001 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.985436e-01 | 0.001 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.985848e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.985848e-01 | 0.001 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.986414e-01 | 0.001 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.986752e-01 | 0.001 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.986838e-01 | 0.001 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.988190e-01 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.988414e-01 | 0.001 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.988910e-01 | 0.000 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.988929e-01 | 0.000 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.988929e-01 | 0.000 | 0 | 0 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 9.989452e-01 | 0.000 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.990210e-01 | 0.000 | 0 | 0 |
| Defensins | R-HSA-1461973 | 9.990323e-01 | 0.000 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.991126e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.991329e-01 | 0.000 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.991557e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.992114e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.994026e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.994059e-01 | 0.000 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.994391e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.994537e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.995286e-01 | 0.000 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.995730e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.995883e-01 | 0.000 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.996274e-01 | 0.000 | 0 | 0 |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | R-HSA-2162123 | 9.996274e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.996285e-01 | 0.000 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.996390e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.997021e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.997499e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.997499e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.998052e-01 | 0.000 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 9.998052e-01 | 0.000 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.998098e-01 | 0.000 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.998282e-01 | 0.000 | 0 | 0 |
| Digestion | R-HSA-8935690 | 9.998356e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.998960e-01 | 0.000 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.998960e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.998999e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.998999e-01 | 0.000 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.999048e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.999116e-01 | 0.000 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.999169e-01 | 0.000 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.999169e-01 | 0.000 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.999287e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.999368e-01 | 0.000 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.999368e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999389e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.999505e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999506e-01 | 0.000 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.999513e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.999634e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999676e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999704e-01 | 0.000 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.999788e-01 | 0.000 | 0 | 0 |
| Metal ion assimilation from the host | R-HSA-9638482 | 9.999788e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.999815e-01 | 0.000 | 0 | 0 |
| Scavenging of heme from plasma | R-HSA-2168880 | 9.999918e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999926e-01 | 0.000 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.999929e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999946e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999962e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999964e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999968e-01 | 0.000 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.999976e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999979e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999986e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.999986e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999986e-01 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 9.999988e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999994e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.999994e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.999995e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999995e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999996e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.999996e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999996e-01 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.999997e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999998e-01 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.999998e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999998e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999999e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.999999e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999999e-01 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 9.999999e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Initial triggering of complement | R-HSA-166663 | 1.000000e+00 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 1.000000e+00 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 1.073808e-12 | 11.969 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 1.765366e-12 | 11.753 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.632916e-12 | 11.787 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 4.707712e-11 | 10.327 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 3.660031e-10 | 9.437 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 9.841905e-10 | 9.007 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 2.282845e-09 | 8.642 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 5.021608e-09 | 8.299 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 1.739831e-08 | 7.759 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.038324e-08 | 7.691 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 2.090345e-08 | 7.680 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 2.471080e-08 | 7.607 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 2.443057e-08 | 7.612 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 3.488114e-08 | 7.457 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 4.409165e-08 | 7.356 | 0 | 0 |
| M Phase | R-HSA-68886 | 6.530216e-07 | 6.185 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 8.717406e-07 | 6.060 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.054606e-06 | 5.977 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 1.646230e-06 | 5.784 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.594419e-06 | 5.797 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.594419e-06 | 5.797 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.594419e-06 | 5.797 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.594419e-06 | 5.797 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 2.486378e-06 | 5.604 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 5.435236e-06 | 5.265 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 7.559515e-06 | 5.122 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 9.257873e-06 | 5.033 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.265694e-05 | 4.898 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 1.402897e-05 | 4.853 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.625064e-05 | 4.789 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 1.852161e-05 | 4.732 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.162223e-05 | 4.665 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 2.326750e-05 | 4.633 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 2.776789e-05 | 4.556 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 2.755146e-05 | 4.560 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 2.744160e-05 | 4.562 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 2.564693e-05 | 4.591 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 3.926169e-05 | 4.406 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 4.153383e-05 | 4.382 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 4.433069e-05 | 4.353 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 5.708587e-05 | 4.243 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 5.708587e-05 | 4.243 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 6.434724e-05 | 4.191 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 6.505179e-05 | 4.187 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 6.772564e-05 | 4.169 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 7.547396e-05 | 4.122 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 8.989203e-05 | 4.046 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 1.025737e-04 | 3.989 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 1.090970e-04 | 3.962 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 1.090970e-04 | 3.962 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 1.090970e-04 | 3.962 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.098604e-04 | 3.959 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.141710e-04 | 3.942 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.253170e-04 | 3.902 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 1.387225e-04 | 3.858 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 1.603180e-04 | 3.795 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 1.603180e-04 | 3.795 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 2.522798e-04 | 3.598 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 2.631300e-04 | 3.580 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 2.868714e-04 | 3.542 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 2.961412e-04 | 3.529 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 3.554582e-04 | 3.449 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 3.569977e-04 | 3.447 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 3.676270e-04 | 3.435 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.717582e-04 | 3.430 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 4.241771e-04 | 3.372 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 4.253241e-04 | 3.371 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 4.450036e-04 | 3.352 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 4.563571e-04 | 3.341 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 4.979746e-04 | 3.303 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 4.835372e-04 | 3.316 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 5.212209e-04 | 3.283 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 5.220457e-04 | 3.282 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 6.233298e-04 | 3.205 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 6.869313e-04 | 3.163 | 0 | 0 |
| Myoclonic epilepsy of Lafora | R-HSA-3785653 | 6.946293e-04 | 3.158 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 7.265236e-04 | 3.139 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 7.758067e-04 | 3.110 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 8.974578e-04 | 3.047 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 9.019727e-04 | 3.045 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 9.171449e-04 | 3.038 | 0 | 0 |
| Kinesins | R-HSA-983189 | 9.339296e-04 | 3.030 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 9.401590e-04 | 3.027 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 9.671041e-04 | 3.015 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 9.885722e-04 | 3.005 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 1.076169e-03 | 2.968 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.082433e-03 | 2.966 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.164185e-03 | 2.934 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 1.169483e-03 | 2.932 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 1.183404e-03 | 2.927 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.277052e-03 | 2.894 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 1.302410e-03 | 2.885 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 1.302410e-03 | 2.885 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.365374e-03 | 2.865 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 1.369837e-03 | 2.863 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 1.409266e-03 | 2.851 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 1.576185e-03 | 2.802 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.488812e-03 | 2.827 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.594000e-03 | 2.798 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 1.596243e-03 | 2.797 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 1.601176e-03 | 2.796 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 1.617922e-03 | 2.791 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 1.679432e-03 | 2.775 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.682894e-03 | 2.774 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 1.785965e-03 | 2.748 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 1.794330e-03 | 2.746 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 2.000377e-03 | 2.699 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 2.033113e-03 | 2.692 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 2.178622e-03 | 2.662 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 2.210317e-03 | 2.656 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 2.216430e-03 | 2.654 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 2.257696e-03 | 2.646 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 2.355444e-03 | 2.628 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 2.337300e-03 | 2.631 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 2.419451e-03 | 2.616 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 2.436487e-03 | 2.613 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 2.436487e-03 | 2.613 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 2.436487e-03 | 2.613 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 2.436487e-03 | 2.613 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 2.436487e-03 | 2.613 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 2.502961e-03 | 2.602 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 2.538522e-03 | 2.595 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 2.554381e-03 | 2.593 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 2.804500e-03 | 2.552 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 2.804499e-03 | 2.552 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 2.610225e-03 | 2.583 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 2.705415e-03 | 2.568 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 2.584534e-03 | 2.588 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 2.584534e-03 | 2.588 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.804499e-03 | 2.552 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 2.842743e-03 | 2.546 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 2.972080e-03 | 2.527 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 3.126959e-03 | 2.505 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 3.266031e-03 | 2.486 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 3.266031e-03 | 2.486 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 3.416545e-03 | 2.466 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 3.583958e-03 | 2.446 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 3.659180e-03 | 2.437 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.659180e-03 | 2.437 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 4.058674e-03 | 2.392 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 4.156364e-03 | 2.381 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 4.156364e-03 | 2.381 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 4.093979e-03 | 2.388 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 4.160077e-03 | 2.381 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.160077e-03 | 2.381 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 4.243187e-03 | 2.372 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 4.243187e-03 | 2.372 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 4.446159e-03 | 2.352 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 4.446159e-03 | 2.352 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 4.450266e-03 | 2.352 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 4.493597e-03 | 2.347 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 4.550464e-03 | 2.342 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 4.600683e-03 | 2.337 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 5.276887e-03 | 2.278 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 4.891565e-03 | 2.311 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 5.228017e-03 | 2.282 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 5.197551e-03 | 2.284 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 5.090052e-03 | 2.293 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 4.856146e-03 | 2.314 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 5.473609e-03 | 2.262 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 5.551979e-03 | 2.256 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 5.706599e-03 | 2.244 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 5.729318e-03 | 2.242 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 5.729318e-03 | 2.242 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 5.786398e-03 | 2.238 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 5.924134e-03 | 2.227 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 5.958353e-03 | 2.225 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 5.958353e-03 | 2.225 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 6.224297e-03 | 2.206 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 6.224381e-03 | 2.206 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 6.350712e-03 | 2.197 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 6.658591e-03 | 2.177 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 8.243428e-03 | 2.084 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 7.725110e-03 | 2.112 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 7.725110e-03 | 2.112 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 8.312925e-03 | 2.080 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 6.646093e-03 | 2.177 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 7.584201e-03 | 2.120 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 8.171479e-03 | 2.088 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 6.713020e-03 | 2.173 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.239646e-03 | 2.084 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 7.725110e-03 | 2.112 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 7.528637e-03 | 2.123 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 8.312925e-03 | 2.080 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 8.312925e-03 | 2.080 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 7.069402e-03 | 2.151 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 7.322926e-03 | 2.135 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 7.904441e-03 | 2.102 | 0 | 0 |
| Maturation of protein E | R-HSA-9683683 | 7.295770e-03 | 2.137 | 0 | 0 |
| Maturation of protein E | R-HSA-9694493 | 7.295770e-03 | 2.137 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 8.511885e-03 | 2.070 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 8.530792e-03 | 2.069 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.565440e-03 | 2.067 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 9.135110e-03 | 2.039 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.352854e-03 | 2.029 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 9.873543e-03 | 2.006 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 9.890166e-03 | 2.005 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 9.890166e-03 | 2.005 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 9.890166e-03 | 2.005 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 9.985887e-03 | 2.001 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 1.007474e-02 | 1.997 | 1 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 1.008559e-02 | 1.996 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 1.027927e-02 | 1.988 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 1.040899e-02 | 1.983 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.040899e-02 | 1.983 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 1.107370e-02 | 1.956 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 1.107370e-02 | 1.956 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 1.245517e-02 | 1.905 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 1.245517e-02 | 1.905 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 1.093299e-02 | 1.961 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.124928e-02 | 1.949 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 1.233109e-02 | 1.909 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 1.096521e-02 | 1.960 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.201904e-02 | 1.920 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.243600e-02 | 1.905 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 1.087293e-02 | 1.964 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 1.090445e-02 | 1.962 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 1.086615e-02 | 1.964 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 1.093299e-02 | 1.961 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 1.107370e-02 | 1.956 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.135244e-02 | 1.945 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 1.245517e-02 | 1.905 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 1.225488e-02 | 1.912 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 1.250463e-02 | 1.903 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 1.250463e-02 | 1.903 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 1.274311e-02 | 1.895 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 1.308772e-02 | 1.883 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.315800e-02 | 1.881 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 1.332095e-02 | 1.875 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.371814e-02 | 1.863 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 1.381090e-02 | 1.860 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 1.381090e-02 | 1.860 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 1.402885e-02 | 1.853 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 1.402885e-02 | 1.853 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 1.409046e-02 | 1.851 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.433368e-02 | 1.844 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 1.449492e-02 | 1.839 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 1.450315e-02 | 1.839 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 1.490319e-02 | 1.827 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 1.491751e-02 | 1.826 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 1.505717e-02 | 1.822 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 1.505717e-02 | 1.822 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.505717e-02 | 1.822 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.540336e-02 | 1.812 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 1.545430e-02 | 1.811 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.577881e-02 | 1.802 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 1.858029e-02 | 1.731 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.891956e-02 | 1.723 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 1.888616e-02 | 1.724 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 1.888616e-02 | 1.724 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 1.951278e-02 | 1.710 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 1.701282e-02 | 1.769 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 1.754873e-02 | 1.756 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.705950e-02 | 1.768 | 0 | 0 |
| Glycogen storage diseases | R-HSA-3229121 | 1.891956e-02 | 1.723 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 1.802815e-02 | 1.744 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 1.891956e-02 | 1.723 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 1.858029e-02 | 1.731 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 1.858029e-02 | 1.731 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 1.796010e-02 | 1.746 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 1.701814e-02 | 1.769 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 1.858029e-02 | 1.731 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 1.977436e-02 | 1.704 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 1.982145e-02 | 1.703 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 2.036195e-02 | 1.691 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 2.098036e-02 | 1.678 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 2.098036e-02 | 1.678 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 2.098036e-02 | 1.678 | 0 | 0 |
| Modulation by Mtb of host immune system | R-HSA-9637628 | 2.098036e-02 | 1.678 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 2.123541e-02 | 1.673 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 2.172938e-02 | 1.663 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 2.178702e-02 | 1.662 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 2.218027e-02 | 1.654 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 2.225563e-02 | 1.653 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 2.235735e-02 | 1.651 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 2.288032e-02 | 1.641 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 2.329018e-02 | 1.633 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 2.334739e-02 | 1.632 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 2.525140e-02 | 1.598 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 2.536778e-02 | 1.596 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 2.551662e-02 | 1.593 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 2.708326e-02 | 1.567 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 2.708326e-02 | 1.567 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 2.708326e-02 | 1.567 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 2.765113e-02 | 1.558 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 2.765113e-02 | 1.558 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 2.765113e-02 | 1.558 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 2.781360e-02 | 1.556 | 1 | 1 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 2.787409e-02 | 1.555 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 2.906867e-02 | 1.537 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 2.906867e-02 | 1.537 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 2.906867e-02 | 1.537 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 3.545092e-02 | 1.450 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 3.545092e-02 | 1.450 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.508601e-02 | 1.455 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.320713e-02 | 1.479 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 2.890296e-02 | 1.539 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 3.196355e-02 | 1.495 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 3.196355e-02 | 1.495 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 3.133455e-02 | 1.504 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 3.349274e-02 | 1.475 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 2.898376e-02 | 1.538 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 2.898376e-02 | 1.538 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 3.545092e-02 | 1.450 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 2.855691e-02 | 1.544 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 3.545092e-02 | 1.450 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 2.890296e-02 | 1.539 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 3.284583e-02 | 1.484 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.290070e-02 | 1.483 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 3.056645e-02 | 1.515 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 3.239037e-02 | 1.490 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 3.407148e-02 | 1.468 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 3.316158e-02 | 1.479 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 2.883989e-02 | 1.540 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 3.213560e-02 | 1.493 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 3.508601e-02 | 1.455 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 3.508601e-02 | 1.455 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 3.341699e-02 | 1.476 | 1 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 3.508601e-02 | 1.455 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 3.369788e-02 | 1.472 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 3.213560e-02 | 1.493 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 3.545092e-02 | 1.450 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 3.601375e-02 | 1.444 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 3.601375e-02 | 1.444 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 3.602913e-02 | 1.443 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 3.798210e-02 | 1.420 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 3.798210e-02 | 1.420 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 3.844563e-02 | 1.415 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 3.932361e-02 | 1.405 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 4.020086e-02 | 1.396 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 4.020086e-02 | 1.396 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 4.055289e-02 | 1.392 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 4.174483e-02 | 1.379 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 4.198229e-02 | 1.377 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 4.233862e-02 | 1.373 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 4.233862e-02 | 1.373 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 4.233862e-02 | 1.373 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 4.250028e-02 | 1.372 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 4.251259e-02 | 1.371 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 4.287683e-02 | 1.368 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 4.385528e-02 | 1.358 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 4.415379e-02 | 1.355 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 4.415379e-02 | 1.355 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 4.415379e-02 | 1.355 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 4.415379e-02 | 1.355 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 4.475607e-02 | 1.349 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 4.496579e-02 | 1.347 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 4.620830e-02 | 1.335 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 4.633972e-02 | 1.334 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 4.747121e-02 | 1.324 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 4.755274e-02 | 1.323 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 4.799353e-02 | 1.319 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 4.812944e-02 | 1.318 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 4.857047e-02 | 1.314 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 5.504328e-02 | 1.259 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 5.504328e-02 | 1.259 | 0 | 0 |
| Loss of Function of TGFBR2 in Cancer | R-HSA-3642278 | 5.504328e-02 | 1.259 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 5.504328e-02 | 1.259 | 0 | 0 |
| TGFBR2 Kinase Domain Mutants in Cancer | R-HSA-3645790 | 5.504328e-02 | 1.259 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 5.504328e-02 | 1.259 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 5.091721e-02 | 1.293 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 4.973230e-02 | 1.303 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 4.973230e-02 | 1.303 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 4.973230e-02 | 1.303 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 5.608492e-02 | 1.251 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 6.291899e-02 | 1.201 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 6.291899e-02 | 1.201 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 5.891024e-02 | 1.230 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 6.501045e-02 | 1.187 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 5.648072e-02 | 1.248 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 5.463573e-02 | 1.263 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 5.999642e-02 | 1.222 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 5.449048e-02 | 1.264 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 6.035526e-02 | 1.219 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 5.828022e-02 | 1.234 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 5.299292e-02 | 1.276 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 5.398332e-02 | 1.268 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 6.571651e-02 | 1.182 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 5.891024e-02 | 1.230 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 5.469696e-02 | 1.262 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 5.851722e-02 | 1.233 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 4.953539e-02 | 1.305 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 5.851722e-02 | 1.233 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 5.851722e-02 | 1.233 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 6.522808e-02 | 1.186 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 6.261131e-02 | 1.203 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 5.999642e-02 | 1.222 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 6.291899e-02 | 1.201 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 5.608492e-02 | 1.251 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 6.571651e-02 | 1.182 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 6.571651e-02 | 1.182 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 6.571651e-02 | 1.182 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 4.953539e-02 | 1.305 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 5.608492e-02 | 1.251 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 6.751368e-02 | 1.171 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 6.791239e-02 | 1.168 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 6.791239e-02 | 1.168 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 6.861647e-02 | 1.164 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 6.861647e-02 | 1.164 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 7.028879e-02 | 1.153 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 7.320172e-02 | 1.135 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 7.374928e-02 | 1.132 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 7.481683e-02 | 1.126 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 7.583386e-02 | 1.120 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 7.679250e-02 | 1.115 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 7.787491e-02 | 1.109 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 7.804266e-02 | 1.108 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 7.804266e-02 | 1.108 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 7.804266e-02 | 1.108 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 7.804714e-02 | 1.108 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 7.804714e-02 | 1.108 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 7.809271e-02 | 1.107 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 7.809271e-02 | 1.107 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 7.809271e-02 | 1.107 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 7.809271e-02 | 1.107 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 7.847776e-02 | 1.105 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 7.875317e-02 | 1.104 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 7.907673e-02 | 1.102 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 7.907673e-02 | 1.102 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 8.080817e-02 | 1.093 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 8.097796e-02 | 1.092 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 8.097796e-02 | 1.092 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 8.248575e-02 | 1.084 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 8.268595e-02 | 1.083 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 8.388058e-02 | 1.076 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 8.388058e-02 | 1.076 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 8.398672e-02 | 1.076 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 8.398672e-02 | 1.076 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 8.473619e-02 | 1.072 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 8.624973e-02 | 1.064 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 8.633184e-02 | 1.064 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 8.633184e-02 | 1.064 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 8.904411e-02 | 1.050 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 8.904411e-02 | 1.050 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 8.904411e-02 | 1.050 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 8.904411e-02 | 1.050 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 8.904411e-02 | 1.050 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 8.904411e-02 | 1.050 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 8.904411e-02 | 1.050 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 8.904411e-02 | 1.050 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 8.904411e-02 | 1.050 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 8.956827e-02 | 1.048 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 9.059256e-02 | 1.043 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 9.112720e-02 | 1.040 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 9.144244e-02 | 1.039 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 1.098487e-01 | 0.959 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 1.098487e-01 | 0.959 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 1.098487e-01 | 0.959 | 0 | 0 |
| Signaling by MAP2K mutants | R-HSA-9652169 | 1.098487e-01 | 0.959 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.048082e-01 | 0.980 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 1.048082e-01 | 0.980 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 1.048082e-01 | 0.980 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.048082e-01 | 0.980 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 1.247732e-01 | 0.904 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 1.247732e-01 | 0.904 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 1.212179e-01 | 0.916 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 1.374740e-01 | 0.862 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 1.374740e-01 | 0.862 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 1.131751e-01 | 0.946 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 1.004325e-01 | 0.998 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 1.007466e-01 | 0.997 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 1.302394e-01 | 0.885 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 1.358257e-01 | 0.867 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 1.262993e-01 | 0.899 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 1.251933e-01 | 0.902 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 9.523550e-02 | 1.021 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.058523e-01 | 0.975 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 1.221767e-01 | 0.913 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.314638e-01 | 0.881 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 1.247732e-01 | 0.904 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 1.058523e-01 | 0.975 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 1.061840e-01 | 0.974 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.164381e-01 | 0.934 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.043461e-01 | 0.982 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.028820e-01 | 0.988 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 1.140569e-01 | 0.943 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 1.140569e-01 | 0.943 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 1.374740e-01 | 0.862 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 1.212179e-01 | 0.916 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 1.303889e-01 | 0.885 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 1.245835e-01 | 0.905 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 9.374902e-02 | 1.028 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 1.043461e-01 | 0.982 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 1.212179e-01 | 0.916 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 1.262993e-01 | 0.899 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 1.040929e-01 | 0.983 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 1.170236e-01 | 0.932 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 1.370616e-01 | 0.863 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 1.148938e-01 | 0.940 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 1.075968e-01 | 0.968 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.048082e-01 | 0.980 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 1.280905e-01 | 0.892 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 9.285971e-02 | 1.032 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 1.058109e-01 | 0.975 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 1.162400e-01 | 0.935 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 1.207361e-01 | 0.918 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 1.098487e-01 | 0.959 | 0 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 1.007466e-01 | 0.997 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 1.341113e-01 | 0.873 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.307958e-01 | 0.883 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 1.247732e-01 | 0.904 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 9.510167e-02 | 1.022 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 9.510167e-02 | 1.022 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 1.178581e-01 | 0.929 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 9.669146e-02 | 1.015 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 1.178581e-01 | 0.929 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 1.374740e-01 | 0.862 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 1.131751e-01 | 0.946 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 1.166036e-01 | 0.933 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 1.058523e-01 | 0.975 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 1.212179e-01 | 0.916 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 9.978355e-02 | 1.001 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 1.174258e-01 | 0.930 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 1.212179e-01 | 0.916 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 1.384572e-01 | 0.859 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 1.384572e-01 | 0.859 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 1.400852e-01 | 0.854 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 1.401149e-01 | 0.854 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 1.401149e-01 | 0.854 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.409223e-01 | 0.851 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 1.409223e-01 | 0.851 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.421946e-01 | 0.847 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 1.458737e-01 | 0.836 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 1.459774e-01 | 0.836 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 1.459774e-01 | 0.836 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 1.487616e-01 | 0.828 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 1.544376e-01 | 0.811 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 1.544948e-01 | 0.811 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 1.573270e-01 | 0.803 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 1.573270e-01 | 0.803 | 0 | 0 |
| S Phase | R-HSA-69242 | 1.582079e-01 | 0.801 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 1.609396e-01 | 0.793 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 1.609396e-01 | 0.793 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 1.631791e-01 | 0.787 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.633658e-01 | 0.787 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.639387e-01 | 0.785 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 1.639387e-01 | 0.785 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 1.639387e-01 | 0.785 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.691762e-01 | 0.772 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 1.694871e-01 | 0.771 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 1.694871e-01 | 0.771 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 1.706926e-01 | 0.768 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.711189e-01 | 0.767 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH6 | R-HSA-5632968 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) | R-HSA-5619043 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective F8 binding to von Willebrand factor | R-HSA-9672393 | 1.711189e-01 | 0.767 | 0 | 0 |
| TGFBR2 MSI Frameshift Mutants in Cancer | R-HSA-3642279 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.711189e-01 | 0.767 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 1.711189e-01 | 0.767 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.711189e-01 | 0.767 | 0 | 0 |
| Activation and oligomerization of BAK protein | R-HSA-111452 | 1.711189e-01 | 0.767 | 0 | 0 |
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 1.711189e-01 | 0.767 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.711189e-01 | 0.767 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 1.718640e-01 | 0.765 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 1.718640e-01 | 0.765 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 1.718640e-01 | 0.765 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 1.720437e-01 | 0.764 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 1.723692e-01 | 0.764 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.735731e-01 | 0.761 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 1.735731e-01 | 0.761 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 1.735731e-01 | 0.761 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.735731e-01 | 0.761 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 1.796730e-01 | 0.746 | 0 | 0 |
| TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P | R-HSA-6791462 | 2.453691e-01 | 0.610 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.453691e-01 | 0.610 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.453691e-01 | 0.610 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.453691e-01 | 0.610 | 0 | 0 |
| PTEN Loss of Function in Cancer | R-HSA-5674404 | 2.453691e-01 | 0.610 | 0 | 0 |
| Defective HK1 causes hexokinase deficiency (HK deficiency) | R-HSA-5619056 | 2.453691e-01 | 0.610 | 0 | 0 |
| TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P | R-HSA-6791055 | 2.453691e-01 | 0.610 | 0 | 0 |
| Defective VWF binding to collagen type I | R-HSA-9845622 | 2.453691e-01 | 0.610 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 2.453691e-01 | 0.610 | 0 | 0 |
| Activation, myristolyation of BID and translocation to mitochondria | R-HSA-75108 | 3.129721e-01 | 0.504 | 0 | 0 |
| Defective VWF cleavage by ADAMTS13 variant | R-HSA-9845621 | 3.129721e-01 | 0.504 | 0 | 0 |
| Enhanced cleavage of VWF variant by ADAMTS13 | R-HSA-9845619 | 3.129721e-01 | 0.504 | 0 | 0 |
| Glycogen storage disease type XV (GYG1) | R-HSA-3814836 | 3.129721e-01 | 0.504 | 0 | 0 |
| Defective F8 cleavage by thrombin | R-HSA-9672391 | 3.129721e-01 | 0.504 | 0 | 0 |
| Glycogen storage disease type 0 (muscle GYS1) | R-HSA-3828062 | 3.129721e-01 | 0.504 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 2.072698e-01 | 0.683 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 2.072698e-01 | 0.683 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 2.072698e-01 | 0.683 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 2.415634e-01 | 0.617 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.415634e-01 | 0.617 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 2.415634e-01 | 0.617 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 2.415634e-01 | 0.617 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 2.415634e-01 | 0.617 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 2.415634e-01 | 0.617 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 1.914261e-01 | 0.718 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 2.760771e-01 | 0.559 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 2.760771e-01 | 0.559 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 2.760771e-01 | 0.559 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 2.760771e-01 | 0.559 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 2.760771e-01 | 0.559 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 2.760771e-01 | 0.559 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 2.760771e-01 | 0.559 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 2.760771e-01 | 0.559 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 3.104964e-01 | 0.508 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 3.104964e-01 | 0.508 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 2.647527e-01 | 0.577 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 2.647527e-01 | 0.577 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 2.647527e-01 | 0.577 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 3.445615e-01 | 0.463 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 2.010441e-01 | 0.697 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 2.899644e-01 | 0.538 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 2.343880e-01 | 0.630 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 2.201344e-01 | 0.657 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 2.516100e-01 | 0.599 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 3.407433e-01 | 0.468 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 3.407433e-01 | 0.468 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 2.691342e-01 | 0.570 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 2.065144e-01 | 0.685 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 2.065144e-01 | 0.685 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 3.113638e-01 | 0.507 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 2.186374e-01 | 0.660 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 2.436396e-01 | 0.613 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 2.564825e-01 | 0.591 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 2.827574e-01 | 0.549 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 3.343902e-01 | 0.476 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 3.493517e-01 | 0.457 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 3.387806e-01 | 0.470 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.048962e-01 | 0.516 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 2.976272e-01 | 0.526 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 2.503617e-01 | 0.601 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 1.912424e-01 | 0.718 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 2.007434e-01 | 0.697 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 3.533669e-01 | 0.452 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 3.387806e-01 | 0.470 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 2.350975e-01 | 0.629 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 2.336579e-01 | 0.631 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.976272e-01 | 0.526 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 3.259029e-01 | 0.487 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 2.647527e-01 | 0.577 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 1.850187e-01 | 0.733 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 3.155151e-01 | 0.501 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 2.570878e-01 | 0.590 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 2.976272e-01 | 0.526 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 2.698873e-01 | 0.569 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 2.760771e-01 | 0.559 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 2.698873e-01 | 0.569 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 2.901641e-01 | 0.537 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 3.137618e-01 | 0.503 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 3.412969e-01 | 0.467 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 1.850187e-01 | 0.733 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 1.914261e-01 | 0.718 | 0 | 0 |
| Microbial factors inhibit CASP4 activity | R-HSA-9956593 | 2.153385e-01 | 0.667 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 3.153348e-01 | 0.501 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 2.201344e-01 | 0.657 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 2.050197e-01 | 0.688 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 3.323336e-01 | 0.478 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 3.643822e-01 | 0.438 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 2.239300e-01 | 0.650 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 1.908560e-01 | 0.719 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 3.048962e-01 | 0.516 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 3.628433e-01 | 0.440 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 3.628433e-01 | 0.440 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 2.749732e-01 | 0.561 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 3.647628e-01 | 0.438 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.850187e-01 | 0.733 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 3.230397e-01 | 0.491 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 3.533669e-01 | 0.452 | 0 | 0 |
| Translation | R-HSA-72766 | 3.532870e-01 | 0.452 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 2.336579e-01 | 0.631 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 2.343880e-01 | 0.630 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 3.048962e-01 | 0.516 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 3.048962e-01 | 0.516 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 2.976272e-01 | 0.526 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 2.976272e-01 | 0.526 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 3.596239e-01 | 0.444 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 3.596239e-01 | 0.444 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 1.943460e-01 | 0.711 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 2.347956e-01 | 0.629 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 3.034971e-01 | 0.518 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 2.827574e-01 | 0.549 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.850187e-01 | 0.733 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 2.551358e-01 | 0.593 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 2.024905e-01 | 0.694 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 2.611527e-01 | 0.583 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 2.415634e-01 | 0.617 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 1.914261e-01 | 0.718 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 1.914261e-01 | 0.718 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 1.914261e-01 | 0.718 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 2.647527e-01 | 0.577 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 3.445615e-01 | 0.463 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 2.901641e-01 | 0.537 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 2.160420e-01 | 0.665 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 2.611527e-01 | 0.583 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 2.755169e-01 | 0.560 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 2.755169e-01 | 0.560 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 2.949140e-01 | 0.530 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 3.228084e-01 | 0.491 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 3.323336e-01 | 0.478 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 2.757240e-01 | 0.560 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 2.201360e-01 | 0.657 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 2.072698e-01 | 0.683 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 2.436396e-01 | 0.613 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 3.464019e-01 | 0.460 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 3.628433e-01 | 0.440 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 2.065757e-01 | 0.685 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 2.276804e-01 | 0.643 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 3.113638e-01 | 0.507 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.881829e-01 | 0.540 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 3.464019e-01 | 0.460 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 2.343880e-01 | 0.630 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 2.028180e-01 | 0.693 | 0 | 0 |
| Inhibition of Host mRNA Processing and RNA Silencing | R-HSA-168315 | 2.453691e-01 | 0.610 | 0 | 0 |
| Defective Mismatch Repair Associated With MSH2 | R-HSA-5632928 | 2.453691e-01 | 0.610 | 0 | 0 |
| Manipulation of host energy metabolism | R-HSA-9636667 | 2.453691e-01 | 0.610 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 2.415634e-01 | 0.617 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 2.415634e-01 | 0.617 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 2.760771e-01 | 0.559 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 2.398306e-01 | 0.620 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 2.398306e-01 | 0.620 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 3.104964e-01 | 0.508 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 3.153348e-01 | 0.501 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 2.336579e-01 | 0.631 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 2.816601e-01 | 0.550 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 3.412969e-01 | 0.467 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 3.371225e-01 | 0.472 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 3.509784e-01 | 0.455 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 3.048962e-01 | 0.516 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 2.474461e-01 | 0.607 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 2.653447e-01 | 0.576 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 2.381641e-01 | 0.623 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 2.153385e-01 | 0.667 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 3.137618e-01 | 0.503 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 3.596239e-01 | 0.444 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 3.371225e-01 | 0.472 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 3.104964e-01 | 0.508 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 3.412969e-01 | 0.467 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 2.099305e-01 | 0.678 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 3.445615e-01 | 0.463 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 2.239300e-01 | 0.650 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 2.905248e-01 | 0.537 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 3.372235e-01 | 0.472 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 2.201360e-01 | 0.657 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 2.050197e-01 | 0.688 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 2.415634e-01 | 0.617 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 2.398306e-01 | 0.620 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 3.104964e-01 | 0.508 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 3.104964e-01 | 0.508 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 3.048962e-01 | 0.516 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 3.230397e-01 | 0.491 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 3.412969e-01 | 0.467 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 3.412969e-01 | 0.467 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 3.596239e-01 | 0.444 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 3.195221e-01 | 0.495 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 2.682487e-01 | 0.571 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 3.509784e-01 | 0.455 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 1.912424e-01 | 0.718 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 2.691342e-01 | 0.570 | 0 | 0 |
| Immune System | R-HSA-168256 | 3.538910e-01 | 0.451 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 3.131220e-01 | 0.504 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 2.010441e-01 | 0.697 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 3.131220e-01 | 0.504 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 2.698873e-01 | 0.569 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 3.510892e-01 | 0.455 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 3.007089e-01 | 0.522 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 2.928955e-01 | 0.533 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 2.647527e-01 | 0.577 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 2.295131e-01 | 0.639 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 3.445615e-01 | 0.463 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 2.658937e-01 | 0.575 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 3.048962e-01 | 0.516 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 1.905675e-01 | 0.720 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 3.230397e-01 | 0.491 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 2.132671e-01 | 0.671 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 2.295131e-01 | 0.639 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 3.445615e-01 | 0.463 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 2.398306e-01 | 0.620 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 2.698873e-01 | 0.569 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 2.695281e-01 | 0.569 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 3.596239e-01 | 0.444 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 2.879132e-01 | 0.541 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 2.465083e-01 | 0.608 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 2.816601e-01 | 0.550 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 2.336579e-01 | 0.631 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 3.104964e-01 | 0.508 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.445615e-01 | 0.463 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 2.201360e-01 | 0.657 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 2.445059e-01 | 0.612 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 3.291057e-01 | 0.483 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 3.464019e-01 | 0.460 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 2.800849e-01 | 0.553 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 3.323336e-01 | 0.478 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 2.295131e-01 | 0.639 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 2.010441e-01 | 0.697 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 2.905248e-01 | 0.537 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.201344e-01 | 0.657 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.129721e-01 | 0.504 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 2.415634e-01 | 0.617 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.415634e-01 | 0.617 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.104964e-01 | 0.508 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 3.412969e-01 | 0.467 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 3.397534e-01 | 0.469 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 2.295131e-01 | 0.639 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 1.905675e-01 | 0.720 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 3.343902e-01 | 0.476 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 3.407433e-01 | 0.468 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 2.295131e-01 | 0.639 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 3.464019e-01 | 0.460 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 3.104964e-01 | 0.508 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 2.564825e-01 | 0.591 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 2.691278e-01 | 0.570 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 2.398306e-01 | 0.620 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 3.533669e-01 | 0.452 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 3.445615e-01 | 0.463 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 3.137618e-01 | 0.503 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 3.096758e-01 | 0.509 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 3.649016e-01 | 0.438 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 3.660800e-01 | 0.436 | 0 | 0 |
| PKA activation | R-HSA-163615 | 3.660800e-01 | 0.436 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 3.660800e-01 | 0.436 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 3.660800e-01 | 0.436 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 3.660800e-01 | 0.436 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 3.733101e-01 | 0.428 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 3.744001e-01 | 0.427 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 3.744001e-01 | 0.427 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 3.744001e-01 | 0.427 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 3.745226e-01 | 0.427 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 3.745226e-01 | 0.427 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 3.745226e-01 | 0.427 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 3.745226e-01 | 0.427 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 3.745226e-01 | 0.427 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 3.745226e-01 | 0.427 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.745226e-01 | 0.427 | 0 | 0 |
| Intracellular oxygen transport | R-HSA-8981607 | 3.745226e-01 | 0.427 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.745226e-01 | 0.427 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 3.745226e-01 | 0.427 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 3.778363e-01 | 0.423 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 3.780599e-01 | 0.422 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 3.780599e-01 | 0.422 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 3.780599e-01 | 0.422 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 3.780599e-01 | 0.422 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 3.780599e-01 | 0.422 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 3.780599e-01 | 0.422 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 3.793242e-01 | 0.421 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 3.793242e-01 | 0.421 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 3.793242e-01 | 0.421 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 3.793242e-01 | 0.421 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 3.909442e-01 | 0.408 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 3.912451e-01 | 0.408 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 3.912451e-01 | 0.408 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 3.912451e-01 | 0.408 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 3.945565e-01 | 0.404 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 3.945565e-01 | 0.404 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 3.945565e-01 | 0.404 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 3.953733e-01 | 0.403 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 3.958146e-01 | 0.403 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 3.958146e-01 | 0.403 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 3.958146e-01 | 0.403 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 3.958146e-01 | 0.403 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 3.963184e-01 | 0.402 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 3.963184e-01 | 0.402 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 3.984539e-01 | 0.400 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 4.030477e-01 | 0.395 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 4.040714e-01 | 0.394 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 4.040714e-01 | 0.394 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.108198e-01 | 0.386 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 4.108198e-01 | 0.386 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 4.108198e-01 | 0.386 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 4.108198e-01 | 0.386 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 4.108198e-01 | 0.386 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 4.108198e-01 | 0.386 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 4.108198e-01 | 0.386 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 4.108198e-01 | 0.386 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 4.122855e-01 | 0.385 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 4.122855e-01 | 0.385 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 4.136500e-01 | 0.383 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 4.146065e-01 | 0.382 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 4.161491e-01 | 0.381 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 4.161491e-01 | 0.381 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 4.161491e-01 | 0.381 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 4.161491e-01 | 0.381 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 4.162308e-01 | 0.381 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 4.162308e-01 | 0.381 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 4.162308e-01 | 0.381 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 4.162308e-01 | 0.381 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 4.208945e-01 | 0.376 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 4.220032e-01 | 0.375 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 4.229255e-01 | 0.374 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 4.287094e-01 | 0.368 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 4.303253e-01 | 0.366 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 4.303253e-01 | 0.366 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 4.305621e-01 | 0.366 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 4.305621e-01 | 0.366 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 4.305621e-01 | 0.366 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 4.305621e-01 | 0.366 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 4.305621e-01 | 0.366 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 4.305621e-01 | 0.366 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 4.305621e-01 | 0.366 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 4.305621e-01 | 0.366 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 4.328053e-01 | 0.364 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 4.328053e-01 | 0.364 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 4.328053e-01 | 0.364 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 4.337775e-01 | 0.363 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 4.348781e-01 | 0.362 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.360336e-01 | 0.360 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.369208e-01 | 0.360 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 4.369208e-01 | 0.360 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 4.406364e-01 | 0.356 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 4.406364e-01 | 0.356 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 4.407127e-01 | 0.356 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 4.407127e-01 | 0.356 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 4.427047e-01 | 0.354 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 4.427047e-01 | 0.354 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 4.427047e-01 | 0.354 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 4.427047e-01 | 0.354 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 4.427047e-01 | 0.354 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 4.427047e-01 | 0.354 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 4.427047e-01 | 0.354 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 4.427047e-01 | 0.354 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 4.427047e-01 | 0.354 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 4.427047e-01 | 0.354 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 4.427047e-01 | 0.354 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 4.434234e-01 | 0.353 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 4.477795e-01 | 0.349 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 4.507952e-01 | 0.346 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 4.508804e-01 | 0.346 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 4.564808e-01 | 0.341 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 4.627086e-01 | 0.335 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 4.627086e-01 | 0.335 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 4.630542e-01 | 0.334 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 4.648657e-01 | 0.333 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 4.648657e-01 | 0.333 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 4.648657e-01 | 0.333 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 4.687992e-01 | 0.329 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 4.689770e-01 | 0.329 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 4.694935e-01 | 0.328 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 4.696186e-01 | 0.328 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 4.696186e-01 | 0.328 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 4.736087e-01 | 0.325 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 4.736087e-01 | 0.325 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 4.736087e-01 | 0.325 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 4.736087e-01 | 0.325 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 4.736087e-01 | 0.325 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 4.736087e-01 | 0.325 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 4.774391e-01 | 0.321 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 4.776122e-01 | 0.321 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 4.783841e-01 | 0.320 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 4.815838e-01 | 0.317 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 4.815838e-01 | 0.317 | 0 | 0 |
| Defective binding of VWF variant to GPIb:IX:V | R-HSA-9846298 | 4.815838e-01 | 0.317 | 0 | 0 |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | R-HSA-9845620 | 4.815838e-01 | 0.317 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 4.815838e-01 | 0.317 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 4.815838e-01 | 0.317 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 4.815838e-01 | 0.317 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 4.815838e-01 | 0.317 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 4.815838e-01 | 0.317 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 4.815838e-01 | 0.317 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 4.815838e-01 | 0.317 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 4.815838e-01 | 0.317 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 4.815838e-01 | 0.317 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 4.815838e-01 | 0.317 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 4.815838e-01 | 0.317 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 4.865315e-01 | 0.313 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 4.865315e-01 | 0.313 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 4.865315e-01 | 0.313 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.885474e-01 | 0.311 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 4.885474e-01 | 0.311 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 4.885474e-01 | 0.311 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 4.885474e-01 | 0.311 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 4.910389e-01 | 0.309 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 4.934221e-01 | 0.307 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 4.975307e-01 | 0.303 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 4.975307e-01 | 0.303 | 0 | 0 |
| Prolactin receptor signaling | R-HSA-1170546 | 5.034514e-01 | 0.298 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 5.034514e-01 | 0.298 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 5.034514e-01 | 0.298 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 5.034514e-01 | 0.298 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 5.034514e-01 | 0.298 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 5.040494e-01 | 0.298 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 5.092387e-01 | 0.293 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 5.092387e-01 | 0.293 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 5.117054e-01 | 0.291 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 5.117054e-01 | 0.291 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 5.164220e-01 | 0.287 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 5.171158e-01 | 0.286 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 5.171158e-01 | 0.286 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 5.173927e-01 | 0.286 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 5.207741e-01 | 0.283 | 0 | 0 |
| Defects of platelet adhesion to exposed collagen | R-HSA-9823587 | 5.280367e-01 | 0.277 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.280367e-01 | 0.277 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 5.280367e-01 | 0.277 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 5.280367e-01 | 0.277 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 5.280367e-01 | 0.277 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 5.280367e-01 | 0.277 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 5.280367e-01 | 0.277 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 5.280367e-01 | 0.277 | 0 | 0 |
| Pentose phosphate pathway disease | R-HSA-6791465 | 5.280367e-01 | 0.277 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 5.280367e-01 | 0.277 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 5.280367e-01 | 0.277 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 5.280367e-01 | 0.277 | 0 | 0 |
| Intestinal hexose absorption | R-HSA-8981373 | 5.280367e-01 | 0.277 | 0 | 0 |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors | R-HSA-389397 | 5.280367e-01 | 0.277 | 0 | 0 |
| CLEC7A/inflammasome pathway | R-HSA-5660668 | 5.280367e-01 | 0.277 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 5.280367e-01 | 0.277 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 5.280367e-01 | 0.277 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 5.321751e-01 | 0.274 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 5.321751e-01 | 0.274 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 5.321751e-01 | 0.274 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 5.321751e-01 | 0.274 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 5.321751e-01 | 0.274 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 5.321751e-01 | 0.274 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 5.321751e-01 | 0.274 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 5.342954e-01 | 0.272 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 5.352927e-01 | 0.271 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 5.363361e-01 | 0.271 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 5.363361e-01 | 0.271 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 5.373695e-01 | 0.270 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 5.383410e-01 | 0.269 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 5.400848e-01 | 0.268 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 5.523801e-01 | 0.258 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 5.550699e-01 | 0.256 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 5.550699e-01 | 0.256 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 5.550699e-01 | 0.256 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 5.550699e-01 | 0.256 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 5.551636e-01 | 0.256 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 5.554991e-01 | 0.255 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 5.562807e-01 | 0.255 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 5.562807e-01 | 0.255 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 5.562807e-01 | 0.255 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 5.562807e-01 | 0.255 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 5.562807e-01 | 0.255 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 5.562807e-01 | 0.255 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 5.597407e-01 | 0.252 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 5.597407e-01 | 0.252 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 5.653955e-01 | 0.248 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 5.703297e-01 | 0.244 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.703297e-01 | 0.244 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.703297e-01 | 0.244 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 5.703297e-01 | 0.244 | 0 | 0 |
| G2/M DNA replication checkpoint | R-HSA-69478 | 5.703297e-01 | 0.244 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 5.703297e-01 | 0.244 | 0 | 0 |
| Lactose synthesis | R-HSA-5653890 | 5.703297e-01 | 0.244 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.703297e-01 | 0.244 | 0 | 0 |
| Defective factor VIII causes hemophilia A | R-HSA-9662001 | 5.703297e-01 | 0.244 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 5.703297e-01 | 0.244 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 5.703297e-01 | 0.244 | 0 | 0 |
| HDL clearance | R-HSA-8964011 | 5.703297e-01 | 0.244 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 5.703297e-01 | 0.244 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.703297e-01 | 0.244 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 5.713075e-01 | 0.243 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 5.719677e-01 | 0.243 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 5.735743e-01 | 0.241 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 5.735743e-01 | 0.241 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 5.735743e-01 | 0.241 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 5.776312e-01 | 0.238 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 5.776312e-01 | 0.238 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 5.776312e-01 | 0.238 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 5.821618e-01 | 0.235 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 5.823963e-01 | 0.235 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 5.841763e-01 | 0.233 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 5.861251e-01 | 0.232 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 5.861251e-01 | 0.232 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 5.861251e-01 | 0.232 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 5.861251e-01 | 0.232 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 5.875978e-01 | 0.231 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 5.875978e-01 | 0.231 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 5.926989e-01 | 0.227 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 5.943022e-01 | 0.226 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 5.983233e-01 | 0.223 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 5.983233e-01 | 0.223 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 5.996357e-01 | 0.222 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 5.996357e-01 | 0.222 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 6.045865e-01 | 0.219 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 6.088351e-01 | 0.216 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.088351e-01 | 0.216 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 6.088351e-01 | 0.216 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake | R-HSA-9031525 | 6.088351e-01 | 0.216 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis | R-HSA-9632974 | 6.088351e-01 | 0.216 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose | R-HSA-9031528 | 6.088351e-01 | 0.216 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 6.088351e-01 | 0.216 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 6.088351e-01 | 0.216 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 6.088351e-01 | 0.216 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 6.088351e-01 | 0.216 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 6.088351e-01 | 0.216 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 6.088351e-01 | 0.216 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 6.088351e-01 | 0.216 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 6.088351e-01 | 0.216 | 0 | 0 |
| Maturation of replicase proteins | R-HSA-9694301 | 6.088351e-01 | 0.216 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 6.113186e-01 | 0.214 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 6.113186e-01 | 0.214 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 6.113186e-01 | 0.214 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 6.113186e-01 | 0.214 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 6.174809e-01 | 0.209 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 6.183395e-01 | 0.209 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 6.183395e-01 | 0.209 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 6.183395e-01 | 0.209 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 6.183395e-01 | 0.209 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 6.217595e-01 | 0.206 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 6.261134e-01 | 0.203 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 6.289354e-01 | 0.201 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 6.312384e-01 | 0.200 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 6.338390e-01 | 0.198 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 6.353227e-01 | 0.197 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 6.353227e-01 | 0.197 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 6.353227e-01 | 0.197 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 6.353227e-01 | 0.197 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 6.353227e-01 | 0.197 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 6.353227e-01 | 0.197 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 6.353227e-01 | 0.197 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 6.353227e-01 | 0.197 | 0 | 0 |
| Diseases of carbohydrate metabolism | R-HSA-5663084 | 6.359878e-01 | 0.197 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 6.426805e-01 | 0.192 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.438918e-01 | 0.191 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.438918e-01 | 0.191 | 0 | 0 |
| ALKBH3 mediated reversal of alkylation damage | R-HSA-112126 | 6.438918e-01 | 0.191 | 0 | 0 |
| RSK activation | R-HSA-444257 | 6.438918e-01 | 0.191 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.438918e-01 | 0.191 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 6.438918e-01 | 0.191 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 6.438918e-01 | 0.191 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 6.438918e-01 | 0.191 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 6.438918e-01 | 0.191 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 6.438918e-01 | 0.191 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 6.438918e-01 | 0.191 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 6.438918e-01 | 0.191 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 6.438918e-01 | 0.191 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.438918e-01 | 0.191 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 6.438918e-01 | 0.191 | 0 | 0 |
| Intestinal absorption | R-HSA-8963676 | 6.438918e-01 | 0.191 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.438918e-01 | 0.191 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 6.484565e-01 | 0.188 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 6.485256e-01 | 0.188 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 6.485256e-01 | 0.188 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 6.513959e-01 | 0.186 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 6.546006e-01 | 0.184 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 6.546006e-01 | 0.184 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 6.552958e-01 | 0.184 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 6.562981e-01 | 0.183 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 6.562981e-01 | 0.183 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 6.581484e-01 | 0.182 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 6.581484e-01 | 0.182 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 6.581484e-01 | 0.182 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 6.581484e-01 | 0.182 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 6.587577e-01 | 0.181 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 6.628344e-01 | 0.179 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 6.717100e-01 | 0.173 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 6.742293e-01 | 0.171 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 6.742293e-01 | 0.171 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 6.743385e-01 | 0.171 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 6.743385e-01 | 0.171 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 6.758086e-01 | 0.170 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 6.758086e-01 | 0.170 | 0 | 0 |
| MAPK1 (ERK2) activation | R-HSA-112411 | 6.758086e-01 | 0.170 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 6.758086e-01 | 0.170 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 6.758086e-01 | 0.170 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 6.758086e-01 | 0.170 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 6.758086e-01 | 0.170 | 0 | 0 |
| Regulation of signaling by NODAL | R-HSA-1433617 | 6.758086e-01 | 0.170 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 6.758086e-01 | 0.170 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 6.758086e-01 | 0.170 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 6.758086e-01 | 0.170 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 6.798139e-01 | 0.168 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 6.798139e-01 | 0.168 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 6.798139e-01 | 0.168 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 6.798139e-01 | 0.168 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 6.798139e-01 | 0.168 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 6.798139e-01 | 0.168 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 6.854636e-01 | 0.164 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 6.878620e-01 | 0.162 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 6.879015e-01 | 0.162 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 6.888830e-01 | 0.162 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 6.908302e-01 | 0.161 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 6.914610e-01 | 0.160 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 6.914610e-01 | 0.160 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 6.914610e-01 | 0.160 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 6.914610e-01 | 0.160 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 6.930554e-01 | 0.159 | 0 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 6.930554e-01 | 0.159 | 0 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 6.930554e-01 | 0.159 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 6.957267e-01 | 0.158 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 6.975253e-01 | 0.156 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.992673e-01 | 0.155 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 7.003438e-01 | 0.155 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 7.003438e-01 | 0.155 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 7.003438e-01 | 0.155 | 0 | 0 |
| Vitamin C (ascorbate) metabolism | R-HSA-196836 | 7.003438e-01 | 0.155 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 7.034401e-01 | 0.153 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 7.039974e-01 | 0.152 | 0 | 0 |
| MAPK3 (ERK1) activation | R-HSA-110056 | 7.048665e-01 | 0.152 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 7.048665e-01 | 0.152 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 7.048665e-01 | 0.152 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 7.048665e-01 | 0.152 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 7.048665e-01 | 0.152 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 7.048665e-01 | 0.152 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 7.048665e-01 | 0.152 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 7.163704e-01 | 0.145 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 7.197676e-01 | 0.143 | 0 | 0 |
| Serine metabolism | R-HSA-977347 | 7.197676e-01 | 0.143 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 7.232861e-01 | 0.141 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 7.233468e-01 | 0.141 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 7.238430e-01 | 0.140 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 7.238430e-01 | 0.140 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 7.283381e-01 | 0.138 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 7.285483e-01 | 0.138 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 7.304905e-01 | 0.136 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 7.313215e-01 | 0.136 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 7.313215e-01 | 0.136 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.313215e-01 | 0.136 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.313215e-01 | 0.136 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 7.313215e-01 | 0.136 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 7.313215e-01 | 0.136 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 7.313215e-01 | 0.136 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 7.313215e-01 | 0.136 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 7.313215e-01 | 0.136 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 7.313215e-01 | 0.136 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 7.313215e-01 | 0.136 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.313215e-01 | 0.136 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 7.316494e-01 | 0.136 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.341398e-01 | 0.134 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 7.381187e-01 | 0.132 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 7.381187e-01 | 0.132 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 7.381187e-01 | 0.132 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 7.381187e-01 | 0.132 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 7.390092e-01 | 0.131 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 7.390092e-01 | 0.131 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.405119e-01 | 0.130 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 7.447285e-01 | 0.128 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 7.478838e-01 | 0.126 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 7.495598e-01 | 0.125 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 7.520837e-01 | 0.124 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 7.520837e-01 | 0.124 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 7.554065e-01 | 0.122 | 0 | 0 |
| PI3K events in ERBB4 signaling | R-HSA-1250342 | 7.554065e-01 | 0.122 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 7.554065e-01 | 0.122 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 7.554065e-01 | 0.122 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.554065e-01 | 0.122 | 0 | 0 |
| FMO oxidises nucleophiles | R-HSA-217271 | 7.554065e-01 | 0.122 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 7.554065e-01 | 0.122 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 7.554332e-01 | 0.122 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 7.554332e-01 | 0.122 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 7.554332e-01 | 0.122 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 7.571003e-01 | 0.121 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 7.584597e-01 | 0.120 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 7.585690e-01 | 0.120 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 7.673486e-01 | 0.115 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 7.701297e-01 | 0.113 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 7.717494e-01 | 0.113 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 7.717494e-01 | 0.113 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 7.717494e-01 | 0.113 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 7.717494e-01 | 0.113 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 7.717494e-01 | 0.113 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 7.717494e-01 | 0.113 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 7.717494e-01 | 0.113 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 7.740634e-01 | 0.111 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 7.753587e-01 | 0.110 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 7.773338e-01 | 0.109 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 7.773338e-01 | 0.109 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 7.773338e-01 | 0.109 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 7.773338e-01 | 0.109 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 7.773338e-01 | 0.109 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 7.773338e-01 | 0.109 | 0 | 0 |
| Synthesis of GDP-mannose | R-HSA-446205 | 7.773338e-01 | 0.109 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 7.773338e-01 | 0.109 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 7.773338e-01 | 0.109 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 7.773338e-01 | 0.109 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 7.805501e-01 | 0.108 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 7.805501e-01 | 0.108 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 7.844792e-01 | 0.105 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 7.844792e-01 | 0.105 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 7.871071e-01 | 0.104 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 7.871071e-01 | 0.104 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 7.871071e-01 | 0.104 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 7.871071e-01 | 0.104 | 0 | 0 |
| Depurination | R-HSA-73927 | 7.931274e-01 | 0.101 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 7.931274e-01 | 0.101 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 7.972966e-01 | 0.098 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 7.972966e-01 | 0.098 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 7.972966e-01 | 0.098 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 7.972966e-01 | 0.098 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 7.972966e-01 | 0.098 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 7.981325e-01 | 0.098 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 7.981325e-01 | 0.098 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 7.981325e-01 | 0.098 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 8.015471e-01 | 0.096 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 8.041880e-01 | 0.095 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 8.041880e-01 | 0.095 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 8.041880e-01 | 0.095 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.047316e-01 | 0.094 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 8.050977e-01 | 0.094 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 8.050977e-01 | 0.094 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 8.050977e-01 | 0.094 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 8.062655e-01 | 0.094 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 8.082970e-01 | 0.092 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 8.112824e-01 | 0.091 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 8.122126e-01 | 0.090 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 8.134931e-01 | 0.090 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.134931e-01 | 0.090 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 8.151103e-01 | 0.089 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 8.151103e-01 | 0.089 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 8.151103e-01 | 0.089 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 8.151103e-01 | 0.089 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 8.151103e-01 | 0.089 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.151103e-01 | 0.089 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 8.154706e-01 | 0.089 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.154706e-01 | 0.089 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.154706e-01 | 0.089 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 8.154706e-01 | 0.089 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 8.154706e-01 | 0.089 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 8.154706e-01 | 0.089 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 8.157964e-01 | 0.088 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 8.164794e-01 | 0.088 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 8.164794e-01 | 0.088 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 8.164794e-01 | 0.088 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 8.164794e-01 | 0.088 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 8.164794e-01 | 0.088 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 8.164794e-01 | 0.088 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 8.164794e-01 | 0.088 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 8.189709e-01 | 0.087 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 8.189709e-01 | 0.087 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 8.231447e-01 | 0.085 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 8.272912e-01 | 0.082 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 8.278380e-01 | 0.082 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 8.278380e-01 | 0.082 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 8.278380e-01 | 0.082 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 8.278380e-01 | 0.082 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 8.278380e-01 | 0.082 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 8.301304e-01 | 0.081 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 8.310388e-01 | 0.080 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 8.320163e-01 | 0.080 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 8.320163e-01 | 0.080 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.320163e-01 | 0.080 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 8.320163e-01 | 0.080 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 8.320163e-01 | 0.080 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 8.320163e-01 | 0.080 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 8.375526e-01 | 0.077 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 8.390229e-01 | 0.076 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 8.396007e-01 | 0.076 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.397707e-01 | 0.076 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 8.397707e-01 | 0.076 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 8.397707e-01 | 0.076 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 8.397707e-01 | 0.076 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 8.412506e-01 | 0.075 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 8.470792e-01 | 0.072 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 8.470792e-01 | 0.072 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 8.470792e-01 | 0.072 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 8.470792e-01 | 0.072 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 8.470792e-01 | 0.072 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 8.470792e-01 | 0.072 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 8.470792e-01 | 0.072 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 8.470792e-01 | 0.072 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 8.470792e-01 | 0.072 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 8.470792e-01 | 0.072 | 0 | 0 |
| Attachment and Entry | R-HSA-9678110 | 8.470792e-01 | 0.072 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 8.470792e-01 | 0.072 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 8.470792e-01 | 0.072 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 8.470792e-01 | 0.072 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 8.472832e-01 | 0.072 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 8.472832e-01 | 0.072 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 8.472832e-01 | 0.072 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 8.481139e-01 | 0.072 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 8.498042e-01 | 0.071 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 8.499780e-01 | 0.071 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 8.509488e-01 | 0.070 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 8.509488e-01 | 0.070 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 8.509488e-01 | 0.070 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 8.509488e-01 | 0.070 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 8.509488e-01 | 0.070 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 8.509488e-01 | 0.070 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 8.547361e-01 | 0.068 | 0 | 0 |
| Glycine degradation | R-HSA-6783984 | 8.607923e-01 | 0.065 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 8.607923e-01 | 0.065 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 8.607923e-01 | 0.065 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 8.607923e-01 | 0.065 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.607923e-01 | 0.065 | 0 | 0 |
| Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) | R-HSA-9651496 | 8.607923e-01 | 0.065 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 8.607923e-01 | 0.065 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 8.652317e-01 | 0.063 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 8.652317e-01 | 0.063 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 8.657360e-01 | 0.063 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 8.690582e-01 | 0.061 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 8.711973e-01 | 0.060 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 8.717168e-01 | 0.060 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 8.731434e-01 | 0.059 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 8.732764e-01 | 0.059 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 8.732764e-01 | 0.059 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 8.732764e-01 | 0.059 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 8.732764e-01 | 0.059 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 8.732764e-01 | 0.059 | 0 | 0 |
| Metabolism of ingested H2SeO4 and H2SeO3 into H2Se | R-HSA-2408550 | 8.732764e-01 | 0.059 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 8.732764e-01 | 0.059 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 8.734893e-01 | 0.059 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 8.737528e-01 | 0.059 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 8.797268e-01 | 0.056 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 8.801951e-01 | 0.055 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 8.801951e-01 | 0.055 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 8.803434e-01 | 0.055 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 8.810763e-01 | 0.055 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 8.812955e-01 | 0.055 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 8.812955e-01 | 0.055 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 8.812955e-01 | 0.055 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 8.837605e-01 | 0.054 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 8.844072e-01 | 0.053 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 8.846417e-01 | 0.053 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 8.846417e-01 | 0.053 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 8.846417e-01 | 0.053 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 8.846417e-01 | 0.053 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 8.846417e-01 | 0.053 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 8.846417e-01 | 0.053 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 8.846417e-01 | 0.053 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 8.846417e-01 | 0.053 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.869039e-01 | 0.052 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.888857e-01 | 0.051 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 8.932823e-01 | 0.049 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 8.932823e-01 | 0.049 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 8.932823e-01 | 0.049 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 8.949882e-01 | 0.048 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 8.949882e-01 | 0.048 | 0 | 0 |
| mRNA decay by 3' to 5' exoribonuclease | R-HSA-429958 | 8.949882e-01 | 0.048 | 0 | 0 |
| Diseases of hemostasis | R-HSA-9671793 | 8.949882e-01 | 0.048 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 8.949882e-01 | 0.048 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 8.949882e-01 | 0.048 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 8.949882e-01 | 0.048 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 8.949882e-01 | 0.048 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 8.956314e-01 | 0.048 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 8.956314e-01 | 0.048 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 8.956314e-01 | 0.048 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 8.968590e-01 | 0.047 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 8.968590e-01 | 0.047 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 8.968590e-01 | 0.047 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 8.968590e-01 | 0.047 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 8.968590e-01 | 0.047 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.014961e-01 | 0.045 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.042965e-01 | 0.044 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.042965e-01 | 0.044 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.042965e-01 | 0.044 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 9.044073e-01 | 0.044 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.044073e-01 | 0.044 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.044073e-01 | 0.044 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 9.044073e-01 | 0.044 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.048892e-01 | 0.043 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 9.061440e-01 | 0.043 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 9.083911e-01 | 0.042 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.112303e-01 | 0.040 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 9.112303e-01 | 0.040 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 9.129821e-01 | 0.040 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 9.129821e-01 | 0.040 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.129821e-01 | 0.040 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.129821e-01 | 0.040 | 0 | 0 |
| Intrinsic Pathway of Fibrin Clot Formation | R-HSA-140837 | 9.129821e-01 | 0.040 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.142254e-01 | 0.039 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 9.155180e-01 | 0.038 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.176908e-01 | 0.037 | 0 | 0 |
| Collagen chain trimerization | R-HSA-8948216 | 9.176908e-01 | 0.037 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.197195e-01 | 0.036 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.206490e-01 | 0.036 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 9.207882e-01 | 0.036 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 9.207882e-01 | 0.036 | 0 | 0 |
| CS-GAG biosynthesis | R-HSA-2022870 | 9.207882e-01 | 0.036 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.207882e-01 | 0.036 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 9.207882e-01 | 0.036 | 0 | 0 |
| Attachment and Entry | R-HSA-9694614 | 9.207882e-01 | 0.036 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.219858e-01 | 0.035 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.219858e-01 | 0.035 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.219858e-01 | 0.035 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.220340e-01 | 0.035 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.238707e-01 | 0.034 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.272137e-01 | 0.033 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.273013e-01 | 0.033 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.278937e-01 | 0.033 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.278944e-01 | 0.033 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 9.293069e-01 | 0.032 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.297540e-01 | 0.032 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.338750e-01 | 0.030 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.338750e-01 | 0.030 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.343265e-01 | 0.030 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.343635e-01 | 0.029 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 9.343635e-01 | 0.029 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 9.343635e-01 | 0.029 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 9.343635e-01 | 0.029 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 9.343635e-01 | 0.029 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 9.343635e-01 | 0.029 | 0 | 0 |
| ABC transporters in lipid homeostasis | R-HSA-1369062 | 9.343635e-01 | 0.029 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 9.345165e-01 | 0.029 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 9.345165e-01 | 0.029 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 9.350401e-01 | 0.029 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.373367e-01 | 0.028 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 9.384263e-01 | 0.028 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.393607e-01 | 0.027 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.393607e-01 | 0.027 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 9.393607e-01 | 0.027 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 9.402526e-01 | 0.027 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 9.402526e-01 | 0.027 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 9.402526e-01 | 0.027 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 9.402526e-01 | 0.027 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.420939e-01 | 0.026 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 9.425070e-01 | 0.026 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 9.425070e-01 | 0.026 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 9.438632e-01 | 0.025 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 9.438632e-01 | 0.025 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 9.438632e-01 | 0.025 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 9.438632e-01 | 0.025 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.438632e-01 | 0.025 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 9.456136e-01 | 0.024 | 0 | 0 |
| Beta-oxidation of pristanoyl-CoA | R-HSA-389887 | 9.456136e-01 | 0.024 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.456136e-01 | 0.024 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.456136e-01 | 0.024 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.456136e-01 | 0.024 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 9.480463e-01 | 0.023 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.480463e-01 | 0.023 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.480463e-01 | 0.023 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.504938e-01 | 0.022 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 9.504938e-01 | 0.022 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 9.504938e-01 | 0.022 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.504938e-01 | 0.022 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.504938e-01 | 0.022 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.504938e-01 | 0.022 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.504938e-01 | 0.022 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 9.519311e-01 | 0.021 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.533326e-01 | 0.021 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.545187e-01 | 0.020 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 9.549364e-01 | 0.020 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.549364e-01 | 0.020 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.549364e-01 | 0.020 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.549364e-01 | 0.020 | 0 | 0 |
| Synthesis of PE | R-HSA-1483213 | 9.549364e-01 | 0.020 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.555373e-01 | 0.020 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.555373e-01 | 0.020 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.564570e-01 | 0.019 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 9.571258e-01 | 0.019 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.573943e-01 | 0.019 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 9.588837e-01 | 0.018 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.589806e-01 | 0.018 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 9.589806e-01 | 0.018 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.597330e-01 | 0.018 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.626620e-01 | 0.017 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 9.626620e-01 | 0.017 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.648663e-01 | 0.016 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 9.660133e-01 | 0.015 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.660133e-01 | 0.015 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.661761e-01 | 0.015 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.662430e-01 | 0.015 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 9.690639e-01 | 0.014 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.690639e-01 | 0.014 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.697111e-01 | 0.013 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 9.710072e-01 | 0.013 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 9.718409e-01 | 0.012 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.722973e-01 | 0.012 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 9.731389e-01 | 0.012 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.734103e-01 | 0.012 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.737926e-01 | 0.012 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.738801e-01 | 0.011 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.738801e-01 | 0.011 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 9.743688e-01 | 0.011 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.743688e-01 | 0.011 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.743688e-01 | 0.011 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.749132e-01 | 0.011 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.766698e-01 | 0.010 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.766698e-01 | 0.010 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.766698e-01 | 0.010 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.781994e-01 | 0.010 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.785631e-01 | 0.009 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.787644e-01 | 0.009 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.787644e-01 | 0.009 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.788891e-01 | 0.009 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.790336e-01 | 0.009 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.800583e-01 | 0.009 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 9.824067e-01 | 0.008 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.824067e-01 | 0.008 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.824067e-01 | 0.008 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 9.839474e-01 | 0.007 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 9.839474e-01 | 0.007 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.839865e-01 | 0.007 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.839865e-01 | 0.007 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.839865e-01 | 0.007 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.839865e-01 | 0.007 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.842050e-01 | 0.007 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.854245e-01 | 0.006 | 0 | 0 |
| alpha-linolenic acid (ALA) metabolism | R-HSA-2046106 | 9.854245e-01 | 0.006 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 9.854245e-01 | 0.006 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 9.854245e-01 | 0.006 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.865703e-01 | 0.006 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 9.867335e-01 | 0.006 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.869616e-01 | 0.006 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.871395e-01 | 0.006 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.876198e-01 | 0.005 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.879250e-01 | 0.005 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.879250e-01 | 0.005 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.890096e-01 | 0.005 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.890752e-01 | 0.005 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.901352e-01 | 0.004 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 9.904091e-01 | 0.004 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 9.904091e-01 | 0.004 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 9.904091e-01 | 0.004 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 9.910142e-01 | 0.004 | 0 | 0 |
| Synthesis of very long-chain fatty acyl-CoAs | R-HSA-75876 | 9.917133e-01 | 0.004 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.918139e-01 | 0.004 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.919926e-01 | 0.003 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.931354e-01 | 0.003 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.931354e-01 | 0.003 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.934328e-01 | 0.003 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.941951e-01 | 0.003 | 0 | 0 |
| alpha-linolenic (omega3) and linoleic (omega6) acid metabolism | R-HSA-2046104 | 9.943136e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.948246e-01 | 0.002 | 0 | 0 |
| Glyoxylate metabolism and glycine degradation | R-HSA-389661 | 9.952897e-01 | 0.002 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.952897e-01 | 0.002 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.964126e-01 | 0.002 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.967682e-01 | 0.001 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.972097e-01 | 0.001 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.972097e-01 | 0.001 | 0 | 0 |
| Chondroitin sulfate/dermatan sulfate metabolism | R-HSA-1793185 | 9.973231e-01 | 0.001 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.973787e-01 | 0.001 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.977108e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.977828e-01 | 0.001 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.979452e-01 | 0.001 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 9.981636e-01 | 0.001 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.982256e-01 | 0.001 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 9.983197e-01 | 0.001 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.983288e-01 | 0.001 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.983288e-01 | 0.001 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 9.984790e-01 | 0.001 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.987403e-01 | 0.001 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.987403e-01 | 0.001 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.988467e-01 | 0.001 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.988536e-01 | 0.000 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.988779e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.989061e-01 | 0.000 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.990182e-01 | 0.000 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.990182e-01 | 0.000 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.990204e-01 | 0.000 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.990506e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.990564e-01 | 0.000 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.990711e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.991360e-01 | 0.000 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.991360e-01 | 0.000 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.991360e-01 | 0.000 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.991552e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.992137e-01 | 0.000 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.993113e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.994075e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.994075e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.995093e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.995382e-01 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.995852e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.996938e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.997214e-01 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 9.997982e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.998262e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.998690e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.998929e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999018e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999385e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999539e-01 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 9.999577e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.999578e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.999651e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999710e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.999738e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999758e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999782e-01 | 0.000 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.999812e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999857e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999857e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999888e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.999907e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999909e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 9.999959e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999975e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999978e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 9.999988e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999991e-01 | 0.000 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.999993e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999995e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999995e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999996e-01 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 9.999998e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999998e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999999e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999999e-01 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
