MAPKAPK3
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| A0A2R8Y4L2 | S95 | Sugiyama | HNRNPA1L3 HNRNPA1P48 | RPHKVDGRVVEPKRAVSREDsQRPDAHLTVKKIFVGGIKED |
| A0AVT1 | S1048 | Sugiyama | UBA6 MOP4 UBE1L2 | FAPDIDGDEDLPGPPVRYyFsHDTD________________ |
| A4FU28 | S140 | Sugiyama | CTAGE9 | AAAEEARSLEATCEKLSRsNsELEDEILCLEKDLKEEKSKH |
| A5A3E0 | S1068 | Sugiyama | POTEF A26C1B | SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________ |
| A5A3E0 | S939 | Sugiyama | POTEF A26C1B | VALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPE |
| A5A3E0 | Y940 | Sugiyama | POTEF A26C1B | ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA |
| A6NKT7 | T1210 | Sugiyama | RGPD3 RGP3 | KLIQRAEEMKSGLKDFKTFLtNDQTKVAEEENKGSGTGAAG |
| O00115 | S70 | Sugiyama | DNASE2 DNASE2A DNL2 | QYKyLDEssGGWRDGRALINsPEGAVGRSLQPLyRSNTSQL |
| O00159 | S343 | Sugiyama | MYO1C | EESNAQVTTENQLKYLTRLLsVEGSTLREALTHRKIIAKGE |
| O00165 | S192 | Sugiyama | HAX1 HS1BP1 | VWPMDPHPRtREDNDLDsQVsQEGLGPVLQPQPKSYFKsIS |
| O00170 | S43 | Sugiyama | AIP XAP2 | GELPDFQDGTKATFHYRtLHsDDEGtVLDDsRARGKPMELI |
| O00231 | S14 | Sugiyama | PSMD11 | _______MAAAAVVEFQRAQsLLstDREAsIDILHsIVKRD |
| O00273 | S28 | Sugiyama | DFFA DFF1 DFF45 H13 | GVPESGEIRTLKPCLLRRNysREQHGVAAsCLEDLRSKACD |
| O00299 | S211 | Sugiyama | CLIC1 G6 NCC27 | CKKYRGFTIPEAFRGVHRYLsNAyAREEFAstCPDDEEIEL |
| O00418 | S377 | GPS6|SIGNOR|iPTMNet|EPSD | EEF2K | CGsPQVRTLsGSRPPLLRPLsENSGDENMSDVTFDsLPSsP |
| O00488 | S93 | Sugiyama | ZNF593 ZT86 | STNLKTHFRSKDHKKRLKQLsVEPysQEEAERAAGMGSYVP |
| O14545 | S327 | Sugiyama | TRAFD1 FLN29 | DHQTSCNPSRALPsLNtGsssPRGVEEPDVIFQNFLQQAAS |
| O14545 | S409 | Sugiyama | TRAFD1 FLN29 | CDQRPATATNHVTEGIPRLDsQPQEtsPELPRRRVRHQGDL |
| O14545 | S470 | Sugiyama | TRAFD1 FLN29 | PPSRPINNMTATYNQLSRstsGPRPGCQPssPCVPKLsNsD |
| O14639 | S452 | Sugiyama | ABLIM1 ABLIM KIAA0059 LIMAB1 | PtPsAEGyQDVRDRMIHRstsQGsINsPVySRHsYtPTTSR |
| O14715 | T1209 | Sugiyama | RGPD8 RANBP2ALPHA RANBP2L1 RANBP2L3 | KLIQRAEEMKSGLKDFKTFLtNDQTKVTEEENKGsGTGVAG |
| O14745 | S290 | Sugiyama | NHERF1 NHERF SLC9A3R1 | REALAEAALEsPRPALVRsAssDtsEELNsQDsPPKQDSTA |
| O14974 | S507 | Sugiyama | PPP1R12A MBS MYPT1 | KDSKGTRLAyVAPtIPRRLAstsDIEEKENRDSSSLRTsSS |
| O14974 | S910 | Sugiyama | PPP1R12A MBS MYPT1 | yETssTsAGDRyDsLLGRsGsysYLEERKPYSSRLEKDDST |
| O14980 | S1055 | Sugiyama | XPO1 CRM1 | LEEREIALRQADEEKHKRQMsVPGIFNPHEIPEEMCD____ |
| O15027 | S1127 | Sugiyama | SEC16A KIAA0310 SEC16 SEC16L | DAGQQLPPRPPQSSSVSLVSsGSGQAAVPSEQPWPQPVPAL |
| O15067 | S215 | Sugiyama | PFAS KIAA0361 | LDSWDLDFYTKRFQELQRNPstVEAFDLAQsNsEHSRHWFF |
| O15116 | S123 | Sugiyama | LSM1 CASM | QQTKLEAEKLKVQALKDRGLsIPRADtLDEY__________ |
| O15143 | S333 | Sugiyama | ARPC1B ARC41 | GGtAAGAGLDsLHKNsVsQIsVLsGGKAKCSQFCTTGMDGG |
| O15212 | T38 | Sugiyama | PFDN6 HKE2 PFD6 | QLQKDLSKSMSGRQKLEAQLtENNIVKEELALLDGsNVVFK |
| O15226 | T620 | Sugiyama | NKRF ITBA4 NRF | KIAKRDIEQIIRNYARsEsHtDLtFsRELTNDERKQIHQIA |
| O15460 | S531 | Sugiyama | P4HA2 UNQ290/PRO330 | KWVSNKWFHERGQEFLRPCGstEVD________________ |
| O43164 | S253 | Sugiyama | PJA2 KIAA0438 RNF131 | LDsVPLVKssAGDTEFVHQNsQEIQRSSQDEMVSTKQQNNT |
| O43488 | S40 | Sugiyama | AKR7A2 AFAR AFAR1 AKR7 | SPPPEARALAMSRPPPPRVAsVLGTMEMGRRMDAPAsAAAV |
| O43615 | S180 | Sugiyama | TIMM44 MIMT44 TIM44 | AESVSKGGEKLGRTAAFRALsQGVEsVKKEIDDsVLGQtGP |
| O43707 | T69 | Sugiyama | ACTN4 | EKQQRKTFTAWCNsHLRKAGtQIENIDEDFRDGLKLMLLLE |
| O43823 | S323 | Sugiyama | AKAP8 AKAP95 | RKRKQFQLyEEPDtKLARVDsEGDFsENDDAAGDFRsGDEE |
| O60220 | S94 | Sugiyama | TIMM8A DDP DDP1 TIM8A | SQFILNRLEQTQKSKPVFSEsLsD_________________ |
| O60271 | S949 | Sugiyama | SPAG9 HSS KIAA0516 MAPK8IP4 SYD1 HLC6 | EDLSPVYQSSNDSDAYKDQIsVLPNEQDLVREEAQKMSSLL |
| O60343 | S485 | Sugiyama | TBC1D4 AS160 KIAA0603 | CERIEGLYPPRAKLVIQRHLssLtDNEQADIFERVQKMKPV |
| O60566 | S509 | Sugiyama | BUB1B BUBR1 MAD3L SSK1 | IPGMTLSSSVCQVNCCARETsLAENIWQEQPHSKGPsVPFS |
| O60664 | S148 | Sugiyama | PLIN3 M6PRBP1 TIP47 | KVsGAQEMVssAKDTVAtQLsEAVDATRGAVQSGVDKTKsV |
| O60701 | S381 | Sugiyama | UGDH | GAHLHIYDPKVPREQIVVDLsHPGVSEDDQVsRLVTISKDP |
| O60716 | S252 | Sugiyama | CTNND1 KIAA0384 | sRVtRIEERyRPsMEGyRAPsRQDVyGPQPQVRVGGssVDL |
| O60749 | S119 | Sugiyama | SNX2 TRG9 | AVtPVtPttLIAPRIESKsMsAPVIFDRsREEIEEEANGDI |
| O60749 | S365 | Sugiyama | SNX2 TRG9 | AKSAAMLGNsEDHTALSRALsQLAEVEEKIDQLHQEQAFAD |
| O75348 | S65 | Sugiyama | ATP6V1G1 ATP6G ATP6G1 ATP6J | EQyRLQREKEFKAKEAAALGsRGsCstEVEKETQEKMTILQ |
| O75348 | S68 | Sugiyama | ATP6V1G1 ATP6G ATP6G1 ATP6J | RLQREKEFKAKEAAALGsRGsCstEVEKETQEKMTILQtyF |
| O75369 | S1442 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | SKVKIAGPGLGsGVRARVLQsFtVDSSKAGLAPLEVRVLGP |
| O75369 | T1444 | Sugiyama | FLNB FLN1L FLN3 TABP TAP | VKIAGPGLGsGVRARVLQsFtVDSSKAGLAPLEVRVLGPRG |
| O75390 | S83 | Sugiyama | CS | ITVDMMYGGMRGMKGLVyEtsVLDPDEGIRFRGFsIPECQK |
| O75390 | S97 | Sugiyama | CS | GLVyEtsVLDPDEGIRFRGFsIPECQKLLPKAKGGEEPLPE |
| O75534 | S584 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | YSLSKGKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRP |
| O75534 | T589 | Sugiyama | CSDE1 D1S155E KIAA0885 NRU UNR | GKGNKVSAEKVNKtHsVNGItEEADPTIysGKVIRPLRSVD |
| O75569 | S18 | Sugiyama | PRKRA PACT RAX HSD-14 HSD14 | ___MSQSRHRAEAPPLEREDsGtFsLGKMITAKPGKTPIQV |
| O75937 | S81 | Sugiyama | DNAJC8 SPF31 HSPC315 HSPC331 | VLQIDPEVTDEEIKKRFRQLsILVHPDKNQDDADRAQKAFE |
| O75976 | S84 | Sugiyama | CPD | LESALREAAAAGLPGLARLFsIGRSVEGRPLWVLRLTAGLG |
| O76003 | S117 | Sugiyama | GLRX3 PICOT TXNL2 HUSSY-22 | IDRLDGAHAPELTKKVQRHAssGsFLPSANEHLKEDLNLRL |
| O94888 | S280 | Sugiyama | UBXN7 KIAA0794 UBXD7 | EHGQLDGLsssPPKKCARsEsLIDAsEDsQLEAAIRASLQE |
| O94992 | S268 | Sugiyama | HEXIM1 CLP1 EDG1 HIS1 MAQ1 | EDGGsDGMGGDGSEFLQRDFsEtyERyHTEsLQNMsKQELI |
| O95155 | S105 | Sugiyama | UBE4B HDNB1 KIAA0684 UFD2 | LsssPsNsLEtQsQsLsRsQsMDIDGVSCEKsMsQVDVDsG |
| O95453 | S557 | Sugiyama | PARN DAN | KRLNPQCIPYTLQNHYYRNNsFtAPstVGKRNLsPsQEEAG |
| O95625 | S511 | Sugiyama | ZBTB11 | TAKTDFGPDDDTYRSRLRQRsVNEGAYIRLHKGMEKKLQKR |
| O95678 | S162 | Sugiyama | KRT75 K6HF KB18 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| O95785 | S1094 | Sugiyama | WIZ ZNF803 | WYVNGsPIDTLREILKRRTQsRPGGPPNPPGPsPKALAKMM |
| O95816 | S208 | Sugiyama | BAG2 | IKLLEHSKGAGSKTLQQNAEsRFN_________________ |
| O95835 | S464 | Sugiyama | LATS1 WARTS | SPSSGHEIPTWQPNIPVRsNsFNNPLGNRASHSANSQPSAT |
| O96013 | S41 | Sugiyama | PAK4 KIAA1142 | VHTGFDQHEQKFTGLPRQWQsLIEESARRPKPLVDPACITS |
| P00338 | S161 | Sugiyama | LDHA PIG19 | DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH |
| P00491 | S176 | Sugiyama | PNP NP | GDRFPAMsDAyDRtMRQRALstWKQMGEQRELQEGTYVMVA |
| P02538 | S176 | Sugiyama | KRT6A K6A KRT6D | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWT |
| P04040 | T434 | Sugiyama | CAT | QQPSALEHSIQYSGEVRRFNtANDDNVtQVRAFyVNVLNEE |
| P04075 | S176 | Sugiyama | ALDOA ALDA | EHtPsALAIMENANVLARyAsICQQNGIVPIVEPEILPDGD |
| P04075 | S336 | Sugiyama | ALDOA ALDA | GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs |
| P04075 | S36 | Sugiyama | ALDOA ALDA | LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR |
| P04075 | S39 | Sugiyama | ALDOA ALDA | IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy |
| P04075 | S46 | Sugiyama | ALDOA ALDA | PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA |
| P04075 | T49 | Sugiyama | ALDOA ALDA | GILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtADDR |
| P04083 | S170 | Sugiyama | ANXA1 ANX1 LPC1 | RDINRVYREELKRDLAKDItsDtsGDFRNALLsLAKGDRsE |
| P04259 | S176 | Sugiyama | KRT6B K6B KRTL1 | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P04406 | S210 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | GPsGKLWRDGRGALQNIIPAstGAAKAVGKVIPELNGKLtG |
| P04406 | S241 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV |
| P04406 | S312 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | sstFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMA |
| P04406 | S321 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | IALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE______ |
| P04406 | T237 | Sugiyama | GAPDH GAPD CDABP0047 OK/SW-cl.12 | VGKVIPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDD |
| P04792 | S15 | GPS6|SIGNOR|iPTMNet|EPSD|Sugiyama | HSPB1 HSP27 HSP28 | ______MTERRVPFsLLRGPsWDPFRDWyPHsRLFDQAFGL |
| P04792 | S78 | GPS6|SIGNOR|iPTMNet|EPSD|Sugiyama | HSPB1 HSP27 HSP28 | LPPAAIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVs |
| P04792 | S82 | GPS6|SIGNOR|iPTMNet|EPSD|PSP|Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P04792 | S86 | Sugiyama | HSPB1 HSP27 HSP28 | PAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVNHFAP |
| P05023 | S519 | Sugiyama | ATP1A1 | sEPQHLLVMKGAPERILDRCssILLHGKEQPLDEELKDAFQ |
| P05023 | S520 | Sugiyama | ATP1A1 | EPQHLLVMKGAPERILDRCssILLHGKEQPLDEELKDAFQN |
| P05362 | S43 | Sugiyama | ICAM1 | GPGNAQTSVSPSKVILPRGGsVLVTCstsCDQPKLLGIETP |
| P05455 | S94 | Sugiyama | SSB | KSKAELMEIsEDKTKIRRsPsKPLPEVTDEyKNDVKNRsVY |
| P05783 | S93 | Sugiyama | KRT18 CYK18 PIG46 | GMGGIQNEKETMQsLNDRLAsyLDRVRSLETENRRLESKIR |
| P05787 | S104 | Sugiyama | KRT8 CYK8 | IQAVRTQEKEQIKTLNNKFAsFIDKVRFLEQQNKMLETKWS |
| P05787 | S291 | Sugiyama | KRT8 CYK8 | ANRsRAEAEsMyQIKyEELQsLAGKHGDDLRRTKTEISEMN |
| P05997 | S1277 | Sugiyama | COL5A2 | APDDKNKTDPGVHATLKSLSsQIETMRSPDGSKKHPARTCD |
| P06733 | S27 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL |
| P06733 | S291 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | IsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKFtAsA |
| P06733 | S349 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV |
| P06733 | Y287 | Sugiyama | ENO1 ENO1L1 MBPB1 MPB1 | PsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDDWGAWQKF |
| P07195 | S162 | Sugiyama | LDHB | DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH |
| P07195 | S303 | Sugiyama | LDHB | GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt |
| P07195 | T302 | Sugiyama | LDHB | YGIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsAD |
| P07195 | T323 | Sugiyama | LDHB | sVINQKLKDDEVAQLKKsADtLWDIQKDLKDL_________ |
| P07237 | S427 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | WDKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFP |
| P07237 | T428 | Sugiyama | P4HB ERBA2L PDI PDIA1 PO4DB | DKLGEtyKDHENIVIAKMDstANEVEAVKVHsFPtLKFFPA |
| P07339 | S37 | Sugiyama | CTSD CPSD | PASALVRIPLHKFTSIRRtMsEVGGsVEDLIAKGPVSKYSQ |
| P07355 | S184 | Sugiyama | ANXA2 ANX2 ANX2L4 CAL1H LPC2D | sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK |
| P07437 | S168 | Sugiyama | TUBB TUBB5 OK/SW-cl.56 | GTLLISKIREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS |
| P07711 | S329 | Sugiyama | CTSL CTSL1 | GGyVKMAKDRRNHCGIAsAAsyPtV________________ |
| P07737 | S30 | Sugiyama | PFN1 | NLMADGTCQDAAIVGYKDsPsVWAAVPGKtFVNITPAEVGV |
| P07737 | S85 | Sugiyama | PFN1 | tLGGQKCsVIRDsLLQDGEFsMDLRtKstGGAPTFNVtVtK |
| P07737 | T65 | Sugiyama | PFN1 | PAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQDGEFs |
| P07814 | S739 | Sugiyama | EPRS1 EPRS GLNS PARS QARS QPRS PIG32 | TKVEATKNETSAPFKERPtPsLNNNCttsEDsLVLyNRVAV |
| P07864 | S161 | Sugiyama | LDHC LDH3 LDHX | DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH |
| P07900 | S399 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNLVKK |
| P07900 | S50 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | MSLIINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKL |
| P07900 | S53 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG |
| P07900 | S623 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | tyGWTANMERIMKAQALRDNstMGyMAAKKHLEINPDHsII |
| P07900 | T467 | Sugiyama | HSP90AA1 HSP90A HSPC1 HSPCA | LGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKEN |
| P08174 | S106 | Sugiyama | CD55 CR DAF | QWSDIEEFCNRSCEVPtRLNsAsLKQPYITQNyFPVGtVVE |
| P08174 | S138 | Sugiyama | CD55 CR DAF | yFPVGtVVEyECRPGyRREPsLSPKLTCLQNLKWSTAVEFC |
| P08195 | S406 | Sugiyama | SLC3A2 MDU1 | QQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLNAT |
| P08195 | Y404 | Sugiyama | SLC3A2 MDU1 | DLQQILSLLESNKDLLLtssyLsDsGstGEHtKSLVTQYLN |
| P08238 | S391 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | PEYLNFIRGVVDsEDLPLNIsREMLQQsKILKVIRKNIVKK |
| P08238 | S45 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | MSLIINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKL |
| P08238 | S460 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P08238 | S535 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | EPIDEyCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| P08238 | Y457 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | LKLGIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMK |
| P08729 | S104 | Sugiyama | KRT7 SCL | LQRVRQEESEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWT |
| P08758 | S136 | Sugiyama | ANXA5 ANX5 ENX2 PP4 | sRtPEELRAIKQVyEEEyGssLEDDVVGDTSGYYQRMLVVL |
| P09234 | S48 | Sugiyama | SNRPC | RKHKENVKDYYQKWMEEQAQsLIDKTTAAFQQGKIPPTPFS |
| P09382 | S63 | Sugiyama | LGALS1 | CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG |
| P09651 | S95 | Sugiyama | HNRNPA1 HNRPA1 | RPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| P09972 | S176 | Sugiyama | ALDOC ALDC | ERTPSALAILENANVLARyAsICQQNGIVPIVEPEILPDGD |
| P0C0L4 | S1294 | Sugiyama | C4A CO4 CPAMD2 | LHEGKAEMADQASAWLTRQGsFQGGFRSTQDTVIALDALSA |
| P0C0L5 | S1294 | Sugiyama | C4B CO4 CPAMD3; C4B_2 | LHEGKAEMADQAAAWLTRQGsFQGGFRSTQDTVIALDALSA |
| P0CG38 | S1068 | Sugiyama | POTEI | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG39 | S1031 | Sugiyama | POTEJ | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P0CG41 | S140 | Sugiyama | CTAGE8 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| P0DJD0 | T1194 | Sugiyama | RGPD1 RANBP2L6 RGP1 | KLIQRAEEMKSGLKDFKTFLtNDQTKVTEEENKGsGtGAAG |
| P0DPH7 | S54 | Sugiyama | TUBA3C TUBA2 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P10619 | S51 | Sugiyama | CTSA PPGB | DQDEIQRLPGLAKQPSFRQYsGYLKGSGSKHLHYWFVESQK |
| P10809 | S453 | Sugiyama | HSPD1 HSP60 | EEGIVLGGGCALLRCIPALDsLtPANEDQKIGIEIIKRTLK |
| P11142 | S40 | Sugiyama | HSPA8 HSC70 HSP73 HSPA10 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P11532 | S3623 | Sugiyama | DMD | EAKVNGttVssPstsLQRsDssQPMLLRVVGSQTSDSMGEE |
| P11586 | S413 | Sugiyama | MTHFD1 MTHFC MTHFD | LVQALGAHLYQNVFACVRQPsQGPTFGIKGGAAGGGYSQVI |
| P12004 | S152 | Sugiyama | PCNA | EySCVVKMPSGEFARICRDLsHIGDAVVIsCAKDGVKFSAs |
| P12035 | S211 | Sugiyama | KRT3 | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWN |
| P12270 | S2155 | Sugiyama | TPR | PstPtLVVPHRtDGFAEAIHsPQVAGVPRFRFGPPEDMPQT |
| P12277 | S164 | Sugiyama | CKB CKBB | PHCsRGERRAIEKLAVEALssLDGDLAGRyyALKsMtEAEQ |
| P12955 | S162 | Sugiyama | PEPD PRD | SVLLTLRGVNTDSGSVCREAsFDGISKFEVNNTILHPEIVE |
| P13473 | S155 | Sugiyama | LAMP2 | LTVDELLAIRIPLNDLFRCNsLSTLEKNDVVQHYWDVLVQA |
| P13489 | S178 | Sugiyama | RNH1 PRI RNH | SCEPLASVLRAKPDFKELtVsNNDINEAGVRVLCQGLKDSP |
| P13639 | S23 | Sugiyama | EEF2 EF2 | NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA |
| P13639 | S578 | Sugiyama | EEF2 EF2 | LKDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNK |
| P13639 | S584 | Sugiyama | EEF2 EF2 | DHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKHNRLyM |
| P13639 | S593 | Sugiyama | EEF2 EF2 | SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL |
| P13639 | Y579 | Sugiyama | EEF2 EF2 | KDLEEDHACIPIKKSDPVVsyREtVsEEsNVLCLsKsPNKH |
| P13647 | S181 | Sugiyama | KRT5 | IQRVRTEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P13667 | S379 | Sugiyama | PDIA4 ERP70 ERP72 | QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH |
| P13693 | S9 | Sugiyama | TPT1 | ____________MIIYRDLIsHDEMFsDIyKIREIADGLCL |
| P13797 | S339 | Sugiyama | PLS3 | PRIDINMsGFNETDDLKRAEsMLQQADKLGCRQFVTPADVV |
| P13861 | S383 | Sugiyama | PRKAR2A PKR2 PRKAR2 | DVQAFERLLGPCMDIMKRNIsHYEEQLVKMFGssVDLGNLG |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P14625 | S106 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | MKLIINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENAL |
| P14625 | S172 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | VGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSELI |
| P14625 | S514 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | LGVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEK |
| P14625 | S515 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | GVIEDHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQ |
| P14625 | T519 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | DHsNRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIy |
| P14625 | T522 | Sugiyama | HSP90B1 GRP94 HSPC4 TRA1 | NRtRLAKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMA |
| P14649 | S87 | Sugiyama | MYL6B MLC1SA | EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK |
| P14866 | S544 | Sugiyama | HNRNPL HNRPL P/OKcl.14 | LGVKRPSSVKVFSGKsERsssGLLEWEsKSDALETLGFLNH |
| P15311 | S536 | Sugiyama | EZR VIL2 | KRITEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNE |
| P15311 | S539 | Sugiyama | EZR VIL2 | TEAEKNERVQRQLLtLssELsQARDENKRTHNDIIHNENMR |
| P15336 | S62 | Sugiyama | ATF2 CREB2 CREBP1 | LAVHKHKHEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEV |
| P15336 | T69 | Sugiyama | ATF2 CREB2 CREBP1 | HEMtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELA |
| P15336 | T71 | Sugiyama | ATF2 CREB2 CREBP1 | MtLKFGPARNDsVIVADQtPtPtRFLKNCEEVGLFNELAsP |
| P15374 | S128 | Sugiyama | UCHL3 | KDKMHFESGSTLKKFLEEsVsMsPEERARyLENyDAIRVtH |
| P15531 | S122 | Sugiyama | NME1 NDPKA NM23 | GtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELVDy |
| P15924 | S1708 | Sugiyama | DSP | AIEDKSRSLNESKIEIERLQsLTENLTKEHLMLEEELRNLR |
| P16070 | S71 | Sugiyama | CD44 LHR MDU2 MDU3 MIC4 | DLCKAFNSTLPTMAQMEKALsIGFEtCRyGFIEGHVVIPRI |
| P16333 | S85 | Sugiyama | NCK1 NCK | ASIVKNLKDTLGIGKVKRKPsVPDsAsPADDsFVDPGERLy |
| P17066 | S42 | Sugiyama | HSPA6 HSP70B' | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P17544 | S44 | Sugiyama | ATF7 ATFA | LAVHKHKHEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEV |
| P17544 | T51 | Sugiyama | ATF7 ATFA | HEMTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELA |
| P17544 | T53 | Sugiyama | ATF7 ATFA | MTLKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASS |
| P17544 | T55 | Sugiyama | ATF7 ATFA | LKFGPARtDsVIIADQtPtPtRFLKNCEEVGLFNELASSFE |
| P17812 | S573 | Sugiyama | CTPS1 CTPS | HYLQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD__ |
| P17812 | S575 | Sugiyama | CTPS1 CTPS | LQKGCRLsPRDtysDRsGsssPDsEItELKFPsINHD____ |
| P18206 | S809 | Sugiyama | VCL | ELsKtIsPMVMDAKAVAGNIsDPGLQKsFLDsGyRILGAVA |
| P18615 | S115 | Sugiyama | NELFE RD RDBP | KLKDPEKGPVPTFQPFQRsIsADDDLQEsSRRPQRKsLyEs |
| P18615 | S138 | Sugiyama | NELFE RD RDBP | DDLQEsSRRPQRKsLyEsFVsssDRLRELGPDGEEAEGPGA |
| P18621 | S5 | Sugiyama | RPL17 | ________________MVRysLDPENPtKsCKSRGSNLRVH |
| P19338 | S328 | Sugiyama | NCL | NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK |
| P19338 | S460 | Sugiyama | NCL | ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST |
| P19338 | S580 | Sugiyama | NCL | PRGsPNARSQPSKTLFVKGLsEDttEEtLKEsFDGsVRARI |
| P19338 | S619 | Sugiyama | NCL | RIVTDRETGssKGFGFVDFNsEEDAKAAKEAMEDGEIDGNK |
| P20618 | S151 | Sugiyama | PSMB1 PSC5 | PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA |
| P20618 | S157 | Sugiyama | PSMB1 PSC5 | IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL |
| P21108 | S11 | Sugiyama | PRPS1L1 PRPS3 PRPSL | __________MPNIKIFsGssHQDLSQKIADRLGLELGKVV |
| P22059 | S240 | Sugiyama | OSBP OSBP1 | DLSTCNDLIAKHGTALQRsLsELEsLKLPAESNEKIKQVNE |
| P22626 | S189 | Sugiyama | HNRNPA2B1 HNRPA2B1 | IVLQKyHtINGHNAEVRKALsRQEMQEVQssRsGRGGNFGF |
| P22626 | S212 | Sugiyama | HNRNPA2B1 HNRPA2B1 | EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD |
| P23396 | T220 | Sugiyama | RPS3 OK/SW-cl.26 | PKKPLPDHVsIVEPKDEILPttPIsEQKGGKPEPPAMPQPV |
| P23396 | T221 | Sugiyama | RPS3 OK/SW-cl.26 | KKPLPDHVsIVEPKDEILPttPIsEQKGGKPEPPAMPQPVP |
| P23528 | S41 | Sugiyama | CFL1 CFL | RKsstPEEVKKRKKAVLFCLsEDKKNIILEEGKEILVGDVG |
| P23588 | S311 | Sugiyama | EIF4B | YRGGGDRYEDRYDRRDDRsWssRDDysRDDYRRDDRGPPQR |
| P24534 | S141 | Sugiyama | EEF1B2 EEF1B EF1B | ERLAQYESKKAKKPALVAKssILLDVKPWDDEtDMAKLEEC |
| P24666 | S119 | Sugiyama | ACP1 | DLNRKSNQVKTCKAKIELLGsYDPQKQLIIEDPyyGNDsDF |
| P25054 | S1389 | Sugiyama | APC DP2.5 | PKsPPEHYVQETPLMFsRCTsVSsLDSFESRSIASSVQSEP |
| P25054 | S2129 | Sugiyama | APC DP2.5 | NSIVSSLHQAAAAACLsRQAssDSDSILSLKsGIsLGsPFH |
| P25205 | S447 | Sugiyama | MCM3 | EQGRVTIAKAGIHARLNARCsVLAAANPVyGRyDQyKTPME |
| P25705 | S198 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | GIIPRIsVREPMQTGIKAVDsLVPIGRGQRELIIGDRQTGK |
| P25705 | S76 | Sugiyama | ATP5F1A ATP5A ATP5A1 ATP5AL2 ATPM | EERILGADtsVDLEETGRVLsIGDGIARVHGLRNVQAEEMV |
| P25786 | S110 | Sugiyama | PSMA1 HC2 NU PROS30 PSC2 | QECLDSRFVFDRPLPVsRLVsLIGsKTQIPTQRYGRRPYGV |
| P26038 | S527 | Sugiyama | MSN | ERTTEAEKNERVQKHLKALtsELANARDEsKKTANDMIHAE |
| P26373 | S181 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | YKKEKARVItEEEKNFKAFAsLRMARANARLFGIRAKRAKE |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P26373 | S97 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | sLEELRVAGIHKKVARTIGIsVDPRRRNKstEsLQANVQRL |
| P26447 | S60 | Sugiyama | S100A4 CAPL MTS1 | RELPSFLGKRTDEAAFQKLMsNLDSNRDNEVDFQEYCVFLS |
| P26639 | S702 | Sugiyama | TARS1 TARS | ISGTVNIRTRDNKVHGERtIsEtIERLQQLKEFRSKQAEEE |
| P27144 | S195 | Sugiyama | AK4 AK3 AK3L1 | KDVAKPVIELYKSRGVLHQFsGtEtNKIWPYVYTLFSNKIT |
| P27348 | S45 | Sugiyama | YWHAQ | CMKAVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSI |
| P27348 | S63 | Sugiyama | YWHAQ | LLsVAyKNVVGGRRSAWRVIsSIEQKTDTSDKKLQLIKDYR |
| P27540 | T227 | Sugiyama | ARNT BHLHE2 | STLYDQVHPDDVDKLREQLStSENALTGRILDLKTGTVKKE |
| P27708 | S1859 | Sugiyama | CAD | RGIPGLPDGRFHLPPRIHRAsDPGLPAEEPKEKSSRKVAEP |
| P27797 | S52 | Sugiyama | CALR CRTC | GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA |
| P27797 | T34 | Sugiyama | CALR CRTC | LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG |
| P27824 | S362 | Sugiyama | CANX | WDEDMDGEWEAPQIANPRCEsAPGCGVWQRPVIDNPNyKGK |
| P29083 | T285 | Sugiyama | GTF2E1 TF2E1 | HRAsLEGKSAKERPIWLREstVQGAYGsEDMKEGGIDMDAF |
| P29401 | S305 | Sugiyama | TKT | LAtPPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQAL |
| P29401 | S473 | Sugiyama | TKT | AtEKAVELAANTKGICFIRTsRPENAIIyNNNEDFQVGQAK |
| P29401 | T249 | Sugiyama | TKT | GQAKHQPTAIIAKTFKGRGItGVEDKEsWHGKPLPKNMAEQ |
| P29692 | S106 | Sugiyama | EEF1D EF1D | sLEVENQsLRGVVQELQQAIsKLEARLNVLEKssPGHRAtA |
| P29692 | S162 | Sugiyama | EEF1D EF1D | AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY |
| P29692 | S64 | Sugiyama | EEF1D EF1D | sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI |
| P29692 | S86 | Sugiyama | EEF1D EF1D | GPGAssGtsGDHGELVVRIAsLEVENQsLRGVVQELQQAIs |
| P30043 | T190 | Sugiyama | BLVRB FLR SCAN | RGPSRVISKHDLGHFMLRCLttDEyDGHstyPsHQyQ____ |
| P30048 | S199 | Sugiyama | PRDX3 AOP1 | SGLALRGLFIIDPNGVIKHLsVNDLPVGRSVEETLRLVKAF |
| P30050 | S138 | Sugiyama | RPL12 | HRSLARELsGtIKEILGtAQsVGCNVDGRHPHDIIDDINsG |
| P30086 | S139 | Sugiyama | PEBP1 PBP PEBP | RyVWLVyEQDRPLKCDEPILsNRsGDHRGKFKVAsFRKKyE |
| P30101 | T485 | Sugiyama | PDIA3 ERP57 ERP60 GRP58 | KKyEGGRELsDFIsyLQREAtNPPVIQEEKPKKKKKAQEDL |
| P30533 | S242 | Sugiyama | LRPAP1 A2MRAP | TELKEKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWD |
| P30533 | S247 | Sugiyama | LRPAP1 A2MRAP | KLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQSA |
| P30533 | Y246 | Sugiyama | LRPAP1 A2MRAP | EKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQS |
| P31327 | S898 | Sugiyama | CPS1 | LYKMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQIS |
| P31327 | T900 | Sugiyama | CPS1 | KMRDILNMEKTLKGLNsEsMtEEtLKRAKEIGFSDKQISKC |
| P31939 | S202 | Sugiyama | ATIC PURH OK/SW-cl.86 | tAQyDEAISDyFRKQYSKGVsQMPLRyGMNPHQtPAQLytL |
| P31943 | S23 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | LGTEGGEGFVVKVRGLPWsCsADEVQRFFSDCKIQNGAQGI |
| P31943 | S269 | Sugiyama | HNRNPH1 HNRPH HNRPH1 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQsttGH |
| P31946 | S132 | Sugiyama | YWHAB | TQPESKVFyLKMKGDYFRyLsEVAsGDNKQTtVsNsQQAyQ |
| P31946 | S47 | Sugiyama | YWHAB | AMKAVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P31946 | S65 | Sugiyama | YWHAB | LLsVAyKNVVGARRSsWRVIsSIEQKTERNEKKQQMGKEYR |
| P31947 | S45 | Sugiyama | SFN HME1 | FMKGAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsI |
| P32119 | S112 | Sugiyama | PRDX2 NKEFB TDPX1 | KEGGLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFII |
| P32119 | S151 | Sugiyama | PRDX2 NKEFB TDPX1 | IIDGKGVLRQItVNDLPVGRsVDEALRLVQAFQYTDEHGEV |
| P32119 | T142 | Sugiyama | PRDX2 NKEFB TDPX1 | EGIAYRGLFIIDGKGVLRQItVNDLPVGRsVDEALRLVQAF |
| P32969 | S137 | Sugiyama | RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 | FLGEKYIRRVRMRPGVACsVsQAQKDELILEGNDIELVSNS |
| P32969 | S182 | Sugiyama | RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 | QQATTVKNKDIRKFLDGIyVsEKGtVQQADE__________ |
| P33527 | S915 | Sugiyama | ABCC1 MRP MRP1 | QMENGMLVTDsAGKQLQRQLsssssysGDISRHHNstAELQ |
| P34897 | S90 | Sugiyama | SHMT2 | GLELIAsENFCsRAALEALGsCLNNKYSEGYPGKRyyGGAE |
| P34931 | S42 | Sugiyama | HSPA1L | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P34932 | S363 | Sugiyama | HSPA4 APG2 HSPH2 | GATRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAIL |
| P34932 | S76 | Sugiyama | HSPA4 APG2 HSPH2 | VISNAKNTVQGFKRFHGRAFsDPFVEAEKSNLAYDIVQLPT |
| P34932 | T364 | Sugiyama | HSPA4 APG2 HSPH2 | ATRIPAVKEKISKFFGKELsttLNADEAVTRGCALQCAILs |
| P35241 | S533 | Sugiyama | RDX | ERVTETQKNERVKKQLQALssELAQARDETKKTQNDVLHAE |
| P35269 | T389 | Sugiyama | GTF2F1 RAP74 | PPKRERKPsGGSSRGNsRPGtPsAEGGstsstLRAAASKLE |
| P35613 | S246 | Sugiyama | BSG UNQ6505/PRO21383 | VKssEHINEGEtAMLVCKSEsVPPVTDWAWyKITDSEDKAL |
| P35613 | S279 | Sugiyama | BSG UNQ6505/PRO21383 | TDSEDKALMNGSESRFFVsssQGRSELHIENLNMEADPGQy |
| P35900 | S13 | GPS6 | KRT20 | ________MDFSRRSFHRSLsSSLQAPVVSTVGMQRLGTTP |
| P35908 | S191 | Sugiyama | KRT2 KRT2A KRT2E | IQNVKAQEREQIKTLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| P36871 | S134 | Sugiyama | PGM1 | LtAsHNPGGPNGDFGIKFNIsNGGPAPEAITDKIFQISKTI |
| P37108 | S25 | Sugiyama | SRP14 | EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt |
| P37802 | S163 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | LFsGDPNWFPKKSKENPRNFsDNQLQEGKNVIGLQMGtNRG |
| P37802 | S185 | Sugiyama | TAGLN2 KIAA0120 CDABP0035 | NQLQEGKNVIGLQMGtNRGAsQAGMtGyGMPRQIL______ |
| P37837 | S13 | Sugiyama | TALDO1 TAL TALDO TALDOR | ________MsssPVKRQRMEsALDQLKQFTTVVADTGDFHA |
| P38646 | S212 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | tVPAyFNDsQRQAtKDAGQIsGLNVLRVINEPTAAALAyGL |
| P38646 | S89 | Sugiyama | HSPA9 GRP75 HSPA9B mt-HSP70 | VMEGKQAKVLENAEGARttPsVVAFtADGERLVGMPAKRQA |
| P39023 | S13 | Sugiyama | RPL3 OK/SW-cl.32 | ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP |
| P39023 | S265 | Sugiyama | RPL3 OK/SW-cl.32 | HRGLRKVACIGAWHPARVAFsVARAGQKGYHHRTEINKKIY |
| P39687 | S117 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | GNKIKDLstIEPLKKLENLKsLDLFNCEVtNLNDyRENVFK |
| P39687 | T143 | Sugiyama | ANP32A C15orf1 LANP MAPM PHAP1 | CEVtNLNDyRENVFKLLPQLtyLDGyDRDDKEAPDsDAEGY |
| P39748 | S255 | Sugiyama | FEN1 RAD2 | CESIRGIGPKRAVDLIQKHKsIEEIVRRLDPNKYPVPENWL |
| P40337 | S68 | Sugiyama | VHL | LGAEEEMEAGRPRPVLRSVNsREPsQVIFCNRsPRVVLPVW |
| P41091 | S107 | Sugiyama | EIF2S3 EIF2G | KIYKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLV |
| P41091 | T109 | Sugiyama | EIF2S3 EIF2G | YKLDDPSCPRPECyRSCGsstPDEFPtDIPGtKGNFKLVRH |
| P42566 | S796 | Sugiyama | EPS15 AF1P | GtPTRPCPLPPGKRsINKLDsPDPFKLNDPFQPFPGNDsPK |
| P42704 | S742 | Sugiyama | LRPPRC LRP130 | CRHDKVEDALNLKEEFDRLDssAVLDTGKYVGLVRVLAKHG |
| P43243 | S188 | Sugiyama | MATR3 KIAA0723 | EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs |
| P43243 | S195 | Sugiyama | MATR3 KIAA0723 | RDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyD |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P43686 | S117 | Sugiyama | PSMC4 MIP224 TBP7 | DQNTAIVGSTTGSNYYVRILsTIDRELLKPNASVALHKHSN |
| P46060 | S454 | Sugiyama | RANGAP1 KIAA1835 SD | VstFLAFPsPEKLLRLGPKssVLIAQQTDTSDPEKVVSAFL |
| P46087 | S58 | Sugiyama | NOP2 NOL1 NSUN1 | ENsKRLsSRARKRAAKRRLGsVEAPKtNKsPEAKPLPGKLP |
| P46776 | S68 | Sugiyama | RPL27A | yHPGyFGKVGMKHYHLKRNQsFCPtVNLDKLWtLVsEQtRV |
| P46776 | S83 | Sugiyama | RPL27A | LKRNQsFCPtVNLDKLWtLVsEQtRVNAAKNKtGAAPIIDV |
| P46776 | T80 | Sugiyama | RPL27A | HYHLKRNQsFCPtVNLDKLWtLVsEQtRVNAAKNKtGAAPI |
| P46777 | S172 | Sugiyama | RPL5 MSTP030 | RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA |
| P46777 | S224 | Sugiyama | RPL5 MSTP030 | VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH |
| P46779 | S115 | Sugiyama | RPL28 | HMIRKNKYRPDLRMAAIRRAsAILRSQKPVMVKRKRTRPTK |
| P46779 | S14 | Sugiyama | RPL28 | _______MsAHLQWMVVRNCssFLIKRNKQTYsTEPNNLKA |
| P46937 | S109 | Sugiyama | YAP1 YAP65 | RKLPDsFFKPPEPKsHsRQAstDAGtAGALtPQHVRAHssP |
| P46937 | T110 | Sugiyama | YAP1 YAP65 | KLPDsFFKPPEPKsHsRQAstDAGtAGALtPQHVRAHssPA |
| P46937 | T119 | Sugiyama | YAP1 YAP65 | PEPKsHsRQAstDAGtAGALtPQHVRAHssPAsLQLGAVsP |
| P47712 | S729 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | KEAMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA |
| P47712 | S731 | Sugiyama | PLA2G4A CPLA2 PLA2G4 | AMVESIEyRRQNPsRCsVsLsNVEARRFFNKEFLSKPKA__ |
| P48637 | S276 | Sugiyama | GSS | VDGQEIAVVYFRDGYMPRQYsLQNWEARLLLERSHAAKCPD |
| P48643 | S154 | Sugiyama | CCT5 CCTE KIAA0098 | ADGYEQAARVAIEHLDKISDsVLVDIKDTEPLIQTAKTTLG |
| P48668 | S176 | Sugiyama | KRT6C KRT6E | IQRVRAEEREQIKTLNNKFAsFIDKVRFLEQQNKVLDTKWT |
| P48741 | S42 | Sugiyama | HSPA7 HSP70B | VFQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAA |
| P49137 | S358 | Sugiyama | MAPKAPK2 | tsRVLKEDKERWEDVKEEMtsALATMRVDYEQIKIKKIEDA |
| P49137 | T195 | Sugiyama | MAPKAPK2 | QYLHSINIAHRDVKPENLLYtSKRPNAILKLtDFGFAKEtt |
| P49207 | S12 | Sugiyama | RPL34 | _________MVQRLTYRRRLsYNtASNKTRLSRTPGNRIVy |
| P49327 | T2215 | Sugiyama | FASN FAS | DEAsELACPtPKEDGLAQQQtQLNLRSLLVNPEGPtLMRLN |
| P49419 | S84 | Sugiyama | ALDH7A1 ATQ1 | EVIttyCPANNEPIARVRQAsVADyEEtVKKAREAWKIWAD |
| P49588 | S249 | Sugiyama | AARS1 AARS | ILKPLPKKsIDtGMGLERLVsVLQNKMSNYDTDLFVPYFEA |
| P49588 | S775 | Sugiyama | AARS1 AARS | VTGAEAQKALRKAESLKKCLsVMEAKVKAQTAPNKDVQREI |
| P49792 | T2185 | Sugiyama | RANBP2 NUP358 | KLIQRAEEMKSGLKDFKTFLtNDQTKVTEEENKGsGtGAAG |
| P50454 | S141 | Sugiyama | SERPINH1 CBP1 CBP2 HSP47 SERPINH2 PIG14 | STARNVTWKLGsRLyGPssVsFADDFVRssKQHYNCEHSKI |
| P50502 | S181 | Sugiyama | ST13 AAG2 FAM10A1 HIP SNC6 | LQKPNAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| P50542 | S279 | Sugiyama | PEX5 PXR1 | DQFTRPVNTSALDMEFERAKsAIESDVDFWDKLQAELEEMA |
| P50990 | S23 | Sugiyama | CCT8 C21orf112 CCTQ KIAA0002 | LHVPKAPGFAQMLKEGAKHFsGLEEAVyRNIQACKELAQTT |
| P50991 | S444 | Sugiyama | CCT4 CCTD SRB | GGGAPEIELALRLTEYSRTLsGMEsyCVRAFADAMEVIPST |
| P51116 | S504 | Sugiyama | FXR2 FMR1L2 | PTGGRGRGPPPAPRPTSRYNsSsISSVLKDPDsNPYSLLDt |
| P51116 | S620 | Sugiyama | FXR2 FMR1L2 | GsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPsEDsLsG |
| P51116 | Y614 | Sugiyama | FXR2 FMR1L2 | RGNRtDGsIsGDRQPVtVADyIsRAEsQsRQRPPLERTKPs |
| P51151 | S134 | Sugiyama | RAB9A RAB9 | PESFPFVILGNKIDISERQVsTEEAQAWCRDNGDyPyFETS |
| P51659 | S75 | Sugiyama | HSD17B4 EDH17B4 SDR8C1 | ADKVVEEIRRRGGKAVANyDsVEEGEKVVKTALDAFGRIDV |
| P52298 | S13 | Sugiyama | NCBP2 CBP20 PIG55 | ________MSGGLLKALRsDsyVELSQYRDQHFRGDNEEQE |
| P52306 | S597 | Sugiyama | RAP1GDS1 SMGGDS | FLDVVSKLRSHENKSVAQQAsLTEQRLTVES__________ |
| P52597 | S265 | Sugiyama | HNRNPF HNRPF | EySGLSDGYGFTTDLFGRDLsyCLsGMyDHRYGDsEFtVQs |
| P52948 | S623 | Sugiyama | NUP98 ADAR2 | KNLNNsNLFsPVNRDsENLAsPsEyPENGERFsFLSKPVDE |
| P53041 | S403 | Sugiyama | PPP5C PPP5 | DLLWSDPQPQNGRSISKRGVsCQFGPDVTKAFLEENNLDyI |
| P53396 | S455 | Sugiyama | ACLY | ANFLLNAsGststPAPsRtAsFsEsRADEVAPAKKAKPAMP |
| P53396 | S478 | Sugiyama | ACLY | EsRADEVAPAKKAKPAMPQDsVPsPRSLQGKSTTLFSRHTK |
| P53396 | S656 | Sugiyama | ACLY | IGNTGGMLDNILASKLyRPGsVAyVSRsGGMsNELNNIISR |
| P53992 | S378 | Sugiyama | SEC24C KIAA0079 | TTNFLVKDQGNASPRYIRCTsyNIPCTSDMAKQAQVPLAAV |
| P53999 | S118 | Sugiyama | SUB1 PC4 RPO2TC1 | PGRKGIsLNPEQWsQLKEQIsDIDDAVRKL___________ |
| P53999 | S12 | Sugiyama | SUB1 PC4 RPO2TC1 | _________MPKSKELVsssssGsDsDsEVDKKLKRKKQVA |
| P54577 | S338 | Sugiyama | YARS1 YARS | NKLLDPIREKFNTPALKKLAsAAYPDPSKQKPMAKGPAKNs |
| P54652 | S41 | Sugiyama | HSPA2 | VFQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVA |
| P55010 | S10 | Sugiyama | EIF5 | ___________MSVNVNRsVsDQFyRyKMPRLIAKVEGKGN |
| P55036 | S266 | Sugiyama | PSMD4 MCB1 | AGIATTGtEDsDDALLKMtIsQQEFGRTGLPDLSSMTEEEQ |
| P55060 | S342 | Sugiyama | CSE1L CAS XPO2 | ASVCERPHYKNLFEDQNtLtsICEKVIVPNMEFRAADEEAF |
| P55196 | S216 | Sugiyama | AFDN AF6 MLLT4 | SRLAAEVYKDMPETSFTRtIsNPEVVMKRRRQQKLEKRMQE |
| P55196 | S424 | Sugiyama | AFDN AF6 MLLT4 | HTYEDGSDSRDKPKLYRLQLsVtEVGTEKLDDNSIQLFGPG |
| P55735 | S184 | Sugiyama | SEC13 D3S1231E SEC13A SEC13L1 SEC13R | PGsLIDHPSGQKPNYIKRFAsGGCDNLIKLWKEEEDGQWKE |
| P55795 | S269 | Sugiyama | HNRNPH2 FTP3 HNRPH2 | YNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQstTGH |
| P55809 | S113 | Sugiyama | OXCT1 OXCT SCOT | GVDNFGLGLLLRSKQIKRMVsSYVGENAEFERQYLSGELEV |
| P57772 | S28 | Sugiyama | EEFSEC SELB | VNVGVLGHIDSGKTALARALsTTASTAAFDKQPQSRERGIT |
| P60174 | S212 | Sugiyama | TPI1 TPI | WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV |
| P60660 | S30 | Sugiyama | MYL6 | AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P60709 | S239 | Sugiyama | ACTB | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P60709 | S368 | Sugiyama | ACTB | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P60709 | S52 | Sugiyama | ACTB | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P60709 | Y240 | Sugiyama | ACTB | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P60891 | S11 | Sugiyama | PRPS1 | __________MPNIKIFsGssHQDLSQKIADRLGLELGKVV |
| P61247 | S236 | Sugiyama | RPS3A FTE1 MFTL | KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy |
| P61247 | S237 | Sugiyama | RPS3A FTE1 MFTL | MLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGyE |
| P61313 | S100 | Sugiyama | RPL15 EC45 TCBAP0781 | tyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLNsyW |
| P61313 | S97 | Sugiyama | RPL15 EC45 TCBAP0781 | KGAtyGKPVHHGVNQLKFARsLQsVAEERAGRHCGALRVLN |
| P61353 | S86 | Sugiyama | RPL27 | SKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPAL |
| P61758 | T45 | Sugiyama | VBP1 PFDN3 | IPEAVFVEDVDSFMKQPGNEtADtVLKKLDEQYQKYKFMEL |
| P61769 | S31 | Sugiyama | B2M CDABP0092 HDCMA22P | ALLSLSGLEAIQRTPKIQVysRHPAENGKSNFLNCYVsGFH |
| P61916 | S29 | Sugiyama | NPC2 HE1 | LLLALSTAAQAEPVQFKDCGsVDGVIKEVNVsPCPtQPCQL |
| P61978 | S75 | Sugiyama | HNRNPK HNRPK | GAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIE |
| P61978 | S77 | Sugiyama | HNRNPK HNRPK | VIGKGGKNIKALRtDyNAsVsVPDssGPERILsISADIETI |
| P61981 | S46 | Sugiyama | YWHAG | AMKNVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSI |
| P61981 | S64 | Sugiyama | YWHAG | LLsVAyKNVVGARRSsWRVIsSIEQKtsADGNEKKIEMVRA |
| P62195 | S120 | Sugiyama | PSMC5 SUG1 | DKNIDINDVtPNCRVALRNDsytLHKILPNKVDPLVSLMMV |
| P62249 | S9 | Sugiyama | RPS16 | ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN |
| P62258 | S148 | Sugiyama | YWHAE | YHRyLAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHP |
| P62258 | S46 | Sugiyama | YWHAE | SMKKVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssI |
| P62258 | S64 | Sugiyama | YWHAE | LLsVAyKNVIGARRASWRIIssIEQKEENKGGEDKLKMIRE |
| P62266 | S45 | Sugiyama | RPS23 | KQYKKAHLGtALKANPFGGAsHAKGIVLEKVGVEAKQPNSA |
| P62280 | T15 | Sugiyama | RPS11 | ______MADIQTERAyQKQPtIFQNKKRVLLGEtGKEKLPR |
| P62424 | T84 | Sugiyama | RPL7A SURF-3 SURF3 | QRQRAILyKRLKVPPAINQFtQALDRQTAtQLLKLAHKYRP |
| P62736 | S241 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P62736 | S54 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P62736 | Y242 | Sugiyama | ACTA2 ACTSA ACTVS GIG46 | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P62899 | T26 | Sugiyama | RPL31 | KGGEKKKGRsAINEVVtREytINIHKRIHGVGFKKRAPRAL |
| P62906 | S64 | Sugiyama | RPL10A NEDD6 | QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH |
| P62917 | S130 | Sugiyama | RPL8 | GTIVCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKL |
| P62917 | S138 | Sugiyama | RPL8 | EKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSKKVI |
| P62917 | T135 | Sugiyama | RPL8 | CLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSGSK |
| P62917 | Y133 | Sugiyama | RPL8 | VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG |
| P62942 | T22 | Sugiyama | FKBP1A FKBP1 FKBP12 | GVQVEtIsPGDGRtFPKRGQtCVVHytGMLEDGKKFDSSRD |
| P63010 | S531 | Sugiyama | AP2B1 ADTB2 CLAPB1 | TQDSDNPDLRDRGyIyWRLLsTDPVTAKEVVLSEKPLISEE |
| P63104 | S28 | Sugiyama | YWHAZ | QKAKLAEQAERyDDMAACMKsVtEQGAELsNEERNLLsVAy |
| P63104 | S45 | Sugiyama | YWHAZ | CMKsVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssI |
| P63146 | S142 | Sugiyama | UBE2B RAD6B UBCH1 | ANSQAAQLYQENKREYEKRVsAIVEQsWNDS__________ |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P63261 | S239 | Sugiyama | ACTG1 ACTG | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63261 | S368 | Sugiyama | ACTG1 ACTG | sLstFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| P63261 | S52 | Sugiyama | ACTG1 ACTG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKYPIE |
| P63261 | Y240 | Sugiyama | ACTG1 ACTG | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| P63267 | S240 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P63267 | S53 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P63267 | Y241 | Sugiyama | ACTG2 ACTA3 ACTL3 ACTSG | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68032 | S241 | Sugiyama | ACTC1 ACTC | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68032 | S54 | Sugiyama | ACTC1 ACTC | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68032 | Y242 | Sugiyama | ACTC1 ACTC | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68133 | S241 | Sugiyama | ACTA1 ACTA | VALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| P68133 | S54 | Sugiyama | ACTA1 ACTA | PsIVGRPRHQGVMVGMGQKDsyVGDEAQsKRGILTLKyPIE |
| P68133 | Y242 | Sugiyama | ACTA1 ACTA | ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET |
| P68363 | S54 | Sugiyama | TUBA1B | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| P78345 | S253 | Sugiyama | RPP38 | DtsFEDLsKPKRKLADGRQAsVtLQPLKIKKLIPNPNKIRK |
| P78371 | S470 | Sugiyama | CCT2 99D8.1 CCTB | IADNAGYDSADLVAQLRAAHsEGNttAGLDMREGTIGDMAI |
| P83731 | S38 | Sugiyama | RPL24 | GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK |
| P83731 | S86 | Sugiyama | RPL24 | EIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKAQRE |
| P83731 | S9 | Sugiyama | RPL24 | ____________MKVELCsFsGyKIYPGHGRRYARTDGKVF |
| P83731 | T83 | Sugiyama | RPL24 | QsEEIQKKRTRRAVKFQRAItGAsLADIMAKRNQKPEVRKA |
| P84098 | S12 | Sugiyama | RPL19 | _________MSMLRLQKRLAssVLRCGKKKVWLDPNEtNEI |
| P98082 | S723 | Sugiyama | DAB2 DOC2 | DANQLLNKINEPPKPAPRQVsLPVTKstDNAFENPFFKDsF |
| P99999 | S48 | Sugiyama | CYCS CYC | KTGPNLHGLFGRKtGQAPGysytAANKNKGIIWGEDTLMEY |
| Q00341 | S904 | Sugiyama | HDLBP HBP VGL | FHRSVMGPKGSRIQQITRDFsVQIKFPDREENAVHSTEPVV |
| Q00610 | S146 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | AVYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLL |
| Q00610 | S147 | Sugiyama | CLTC CLH17 CLTCL2 KIAA0034 | VYHWSMEGESQPVKMFDRHssLAGCQIINYRTDAKQKWLLL |
| Q00613 | S375 | Sugiyama | HSF1 HSTF1 | TDtEGRPPsPPPtstPEKCLsVACLDKNELSDHLDAMDSNL |
| Q00839 | S267 | Sugiyama | HNRNPU C1orf199 HNRPU SAFA U21.1 | KRPREDHGRGyFEyIEENKysRAKsPQPPVEEEDEHFDDtV |
| Q01105 | S161 | Sugiyama | SET | FDENPyFENKVLSKEFHLNEsGDPssKstEIKWKSGKDLTK |
| Q01105 | T169 | Sugiyama | SET | NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK |
| Q01469 | T68 | Sugiyama | FABP5 | DGKNLTIKTESTLKTtQFSCtLGEKFEETTADGRKTQtVCN |
| Q01546 | S196 | Sugiyama | KRT76 KRT2B KRT2P | IGQVKAQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWE |
| Q01650 | S31 | Sugiyama | SLC7A5 CD98LC LAT1 MPE16 | LAAPAAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNIT |
| Q01650 | S35 | Sugiyama | SLC7A5 CD98LC LAT1 MPE16 | AAEEKEEAREKMLAAKsADGsAPAGEGEGVtLQRNITLLNG |
| Q02543 | S123 | Sugiyama | RPL18A | AGAVtQCyRDMGARHRARAHsIQIMKVEEIAASKCRRPAVK |
| Q02790 | T42 | Sugiyama | FKBP4 FKBP52 | GVDIsPKQDEGVLKVIKREGtGTEMPMIGDRVFVHYTGWLL |
| Q04637 | S1238 | Sugiyama | EIF4G1 EIF4F EIF4G EIF4GI | RDAVKREAALPPVsPLKAALsEEELEKKsKAIIEEyLHLND |
| Q04917 | S46 | Sugiyama | YWHAH YWHA1 | AMKAVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSI |
| Q04917 | S64 | Sugiyama | YWHAH YWHA1 | LLsVAyKNVVGARRSsWRVIsSIEQKTMADGNEKKLEKVKA |
| Q05397 | S677 | Sugiyama | PTK2 FAK FAK1 | KCWAYDPSRRPRFTELKAQLsTILEEEKAQQEERMRMEsRR |
| Q06124 | S142 | Sugiyama | PTPN11 PTP2C SHPTP2 | AEKLLTEKGKHGsFLVREsQsHPGDFVLSVRTGDDKGESND |
| Q06210 | S257 | Sugiyama | GFPT1 GFAT GFPT | FTRWGsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyF |
| Q06210 | S261 | Sugiyama | GFPT1 GFAT GFPT | GsQGERGKDKKGSCNLsRVDsttCLFPVEEKAVEyyFASDA |
| Q06323 | S55 | Sugiyama | PSME1 IFI5111 | KKIsELDAFLKEPALNEANLsNLKAPLDIPVPDPVKEKEKE |
| Q06830 | S152 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | IIDDKGILRQItVNDLPVGRsVDEtLRLVQAFQFtDKHGEV |
| Q06830 | T143 | Sugiyama | PRDX1 PAGA PAGB TDPX2 | EGIsFRGLFIIDDKGILRQItVNDLPVGRsVDEtLRLVQAF |
| Q07021 | S210 | Sugiyama | C1QBP GC1QBP HABP1 SF2P32 | EDEVGQEDEAEsDIFsIREVsFQstGESEWKDTNYTLNTDS |
| Q07157 | S1051 | Sugiyama | TJP1 ZO1 | PDKEPNLTyEPQLPYVEKQAsRDLEQPtyRyEsssytDQFs |
| Q07157 | S1071 | Sugiyama | TJP1 ZO1 | sRDLEQPtyRyEsssytDQFsRNYEHRLRYEDRVPMyEEQW |
| Q08945 | S657 | Sugiyama | SSRP1 FACT80 | MEKKSTPSRGsSSKSsSRQLsEsFKSKEFVssDEsssGENK |
| Q08AD1 | S1313 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | sLNtGDNEsVHsGKRtPRsEsVEGFLsPsRCGsRNGEKDWE |
| Q08AD1 | S464 | Sugiyama | CAMSAP2 CAMSAP1L1 KIAA1078 | FDKEDSVQRstPNRGITRsIsNEGLtLNNsHVsKHIRKNLS |
| Q08J23 | S743 | Sugiyama | NSUN2 SAKI TRM4 | AstGQPDNDVtEGQRAGEPNsPDAEEANsPDVtAGCDPAGV |
| Q09028 | S146 | Sugiyama | RBBP4 RBAP48 | EVNRARYMPQNPCIIATKtPssDVLVFDyTKHPsKPDPsGE |
| Q09666 | S210 | Sugiyama | AHNAK PM227 | tEISNVDVEtQsGKtVIRLPsGsGAAsPtGsAVDIRAGAIs |
| Q10567 | S531 | Sugiyama | AP1B1 ADTB1 BAM22 CLAPB2 | TQDSDNPDLRDRGyIyWRLLsTDPVAAKEVVLAEKPLISEE |
| Q12906 | S20 | Sugiyama | ILF3 DRBF MPHOSPH4 NF90 | _MRPMRIFVNDDRHVMAKHssVyPTQEELEAVQNMVsHtER |
| Q12965 | S1002 | Sugiyama | MYO1E MYO1C | RSNQKSLyTsMARPPLPRQQstssDRVsQtPEsLDFLKVPD |
| Q13131 | S415 | Sugiyama | PRKAA1 AMPK1 | QKSKHQGVRKAKWHLGIRSQsRPNDIMAEVCRAIKQLDYEW |
| Q13137 | S238 | Sugiyama | CALCOCO2 NDP52 | KMSSENEKMGIRVDQLQAQLsTQEKEMEKLVQGDQDKTEQL |
| Q13177 | S20 | Sugiyama | PAK2 | _MsDNGELEDKPPAPPVRMsstIFsTGGKDPLsANHsLKPL |
| Q13206 | S829 | Sugiyama | DDX10 | sEDMENKISDTKKKQGMKKRsNsEVEDVGPTsHNRKKARWD |
| Q13206 | S831 | Sugiyama | DDX10 | DMENKISDTKKKQGMKKRsNsEVEDVGPTsHNRKKARWDTL |
| Q13263 | S471 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | FGsGDDPyssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLE |
| Q13263 | S473 | Sugiyama | TRIM28 KAP1 RNF96 TIF1B | sGDDPyssAEPHVsGVKRsRsGEGEVsGLMRKVPRVsLERL |
| Q13283 | S67 | Sugiyama | G3BP1 G3BP | sNGKPADAVyGQKEIHRKVMsQNFtNCHTKIRHVDAHATLN |
| Q13409 | S92 | Sugiyama | DYNC1I2 DNCI2 DNCIC2 | ESPIVFSEYWVPPPMsPSSKsVStPsEAGsQDsGDGAVGsR |
| Q13428 | S1230 | Sugiyama | TCOF1 | GLTPANSQASKAtPKLDssPsVsstLAAKDDPDGKQEAKPQ |
| Q13464 | S482 | Sugiyama | ROCK1 | KIMKELDEEGNQRRNLEsTVsQIEKEKMLLQHRINEYQRKA |
| Q13464 | S576 | Sugiyama | ROCK1 | TESDTAVRLRKSHTEMSKSIsQLESLNRELQERNRILENSK |
| Q13509 | S168 | Sugiyama | TUBB3 TUBB4 | GTLLISKVREEYPDRIMNtFsVVPsPKVSDTVVEPYNATLS |
| Q13573 | S182 | Sugiyama | SNW1 SKIIP SKIP | AMPVRAADKLAPAQyIRytPsQQGVAFNsGAKQRVIRMVEM |
| Q13596 | S368 | Sugiyama | SNX1 | AKSLAMLGSSEDNTALSRALsQLAEVEEKIEQLHQEQANND |
| Q13671 | S611 | Sugiyama | RIN1 | GLGQAHTLPLSPVQELRRsLsLWEQRRLPATHCFQHLLRVA |
| Q14126 | S551 | Sugiyama | DSG2 CDHF5 | FSVIDKPPGMAEKWKIARQEstsVLLQQSEKKLGRSEIQFL |
| Q14126 | S553 | Sugiyama | DSG2 CDHF5 | VIDKPPGMAEKWKIARQEstsVLLQQSEKKLGRSEIQFLIS |
| Q14141 | S411 | Sugiyama | SEPTIN6 KIAA0128 SEP2 SEPT6 | DEVNAFKQRKTAAELLQsQGsQAGGsQtLKRDKEKKNNPWL |
| Q14152 | S492 | Sugiyama | EIF3A EIF3S10 KIAA0139 | VDAARHCDLQVRIDHTSRTLsFGsDLNyAtREDAPIGPHLQ |
| Q14160 | S1226 | Sugiyama | SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL | VIANPFAAGIGHRNsLEsIssIDRELsPEGPGKEKELPGQT |
| Q14203 | S31 | Sugiyama | DCTN1 | RTPSGSRMsAEASARPLRVGsRVEVIGKGHRGTVAYVGATL |
| Q14204 | S2384 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | FSEDVLSTDMIFNNFLARLRsIPLDEGEDEAQRRRKGKEDE |
| Q14204 | S4162 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | GRIFVFEPPPGVKANMLRTFssIPVSRICKSPNERARLYFL |
| Q14204 | S4163 | Sugiyama | DYNC1H1 DHC1 DNCH1 DNCL DNECL DYHC KIAA0325 | RIFVFEPPPGVKANMLRTFssIPVSRICKSPNERARLYFLL |
| Q14247 | S282 | Sugiyama | CTTN EMS1 | QKDyKTGFGGKFGVQsERQDsAAVGFDyKEKLAKHEsQQDy |
| Q14247 | S432 | Sugiyama | CTTN EMS1 | EERLPssPVyEDAAsFKAELsyRGPVsGtEPEPVysMEAAD |
| Q14457 | S90 | EPSD|PSP | BECN1 GT197 | IETPRQDGVSRRFIPPARMMsTEsANsFTLIGEASDGGtME |
| Q14568 | S50 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | MSLIINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKL |
| Q14568 | S53 | Sugiyama | HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 | IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG |
| Q14676 | T447 | Sugiyama | MDC1 KIAA0170 NFBD1 | WNRDAEEDMPQRVVLLQRsQtttERDsDtDVEEEELPVENR |
| Q14677 | S210 | Sugiyama | CLINT1 ENTH EPN4 EPNR KIAA0171 | KNKSAFPFSDKLGELsDKIGstIDDtIsKFRRKDREDsPER |
| Q14683 | S1015 | Sugiyama | SMC1A DXS423E KIAA0178 SB1.8 SMC1 SMC1L1 | AEEEIKQEMNtLQQKLNEQQsVLQRIAAPNMKAMEKLESVR |
| Q14697 | S169 | Sugiyama | GANAB G2AN KIAA0088 | IILTARPFRLDLLEDRSLLLsVNARGLLEFEHQRAPRVsQG |
| Q14697 | S52 | Sugiyama | GANAB G2AN KIAA0088 | AVDRSNFKtCEEssFCKRQRsIRPGLsPyRALLDSLQLGPD |
| Q14847 | S99 | Sugiyama | LASP1 MLN50 | ELQsQVRYKEEFEKNKGKGFsVVADtPELQRIKKTQDQIsN |
| Q14966 | S1228 | Sugiyama | ZNF638 NP220 ZFML | DLEKKGAEIINPKTALLPSDsVFAEERNLKGILEEsPsEAE |
| Q14980 | S1757 | Sugiyama | NUMA1 NMP22 NUMA | ITSKLPRtQPDGtsVPGEPAsPIsQRLPPKVEsLEsLyFtP |
| Q14BN4 | S280 | Sugiyama | SLMAP KIAA1601 SLAP UNQ1847/PRO3577 | RVLQEKIEVVRKLSEVERSLsNTEDECTHLKEMNERTQEEL |
| Q14C86 | S903 | Sugiyama | GAPVD1 GAPEX5 KIAA1521 RAP6 | EMEAFKQRHSYPERLVRsRssDIVSSVRRPMSDPSWNRRPG |
| Q14CN4 | S138 | Sugiyama | KRT72 K6IRS2 KB35 KRT6 KRT6IRS2 | IQRVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWN |
| Q15003 | S78 | Sugiyama | NCAPH BRRN BRRN1 CAPH KIAA0074 | NDDEKERLQRRRsRVFDLQFstDsPRLLAsPsSRsIDIsAT |
| Q15021 | S1330 | Sugiyama | NCAPD2 CAPD2 CNAP1 KIAA0159 | sQRAPsAKKPSTGSRyQPLAstAsDNDFVtPEPRRTTRRHP |
| Q15084 | S377 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | PAMAAINARKMKFALLKGsFsEQGINEFLRELsFGRGstAP |
| Q15084 | S389 | Sugiyama | PDIA6 ERP5 P5 TXNDC7 | FALLKGsFsEQGINEFLRELsFGRGstAPVGGGAFPtIVER |
| Q15121 | S116 | Sugiyama | PEA15 | DtKLtRIPsAKKYKDIIRQPsEEEIIKLAPPPKKA______ |
| Q15154 | S1229 | Sugiyama | PCM1 | TPWLYEQEGEVEKPFIKTGFsVSVEKSTSSNRKNQLDTNGR |
| Q15276 | S407 | Sugiyama | RABEP1 RAB5EP RABPT5 RABPT5A | GDPFSKSDNDMFKDGLRRAQstDsLGtsGsLQSKALGYNYK |
| Q15276 | T408 | Sugiyama | RABEP1 RAB5EP RABPT5 RABPT5A | DPFSKSDNDMFKDGLRRAQstDsLGtsGsLQSKALGYNYKA |
| Q15293 | T76 | Sugiyama | RCN1 RCN | FQYDHEAFLGKEDsKtFDQLtPDEsKERLGKIVDRIDNDGD |
| Q15785 | S93 | Sugiyama | TOMM34 URCC3 | DCTSALALVPFSIKPLLRRAsAyEALEKYPMAYVDYKTVLQ |
| Q16204 | S244 | Sugiyama | CCDC6 D10S170 TST1 | LEAEKRILQEKLDQPVsAPPsPRDIsMEIDsPENMMRHIRF |
| Q16204 | S323 | Sugiyama | CCDC6 D10S170 TST1 | RLQRKLQREMERREALCRQLsEsEssLEMDDERYFNEMsAQ |
| Q16513 | S583 | Sugiyama | PKN2 PRK2 PRKCL2 | VTKLDFDLEPEPPPAPPRAssLGEIDEssELRVLDIPGQDs |
| Q16576 | S145 | Sugiyama | RBBP7 RBAP46 | EVNRARYMPQNPHIIATKtPssDVLVFDyTKHPAKPDPsGE |
| Q16644 | S337 | Sugiyama | MAPKAPK3 | tARVLQEDKDHWDEVKEEMTsALATMRVDYDQVKIKDLKTS |
| Q16644 | S46 | Sugiyama | MAPKAPK3 | GAPGGRREPKKyAVTDDyQLsKQVLGLGVNGKVLECFHRRT |
| Q16644 | T175 | Sugiyama | MAPKAPK3 | QFLHSHNIAHRDVKPENLLYtSKEKDAVLKLTDFGFAKEtt |
| Q16644 | T201 | Sugiyama | MAPKAPK3 | AVLKLTDFGFAKEttQNALQtPCytPYYVAPEVLGPEKYDK |
| Q16644 | T205 | Sugiyama | MAPKAPK3 | LTDFGFAKEttQNALQtPCytPYYVAPEVLGPEKYDKSCDM |
| Q16644 | Y204 | Sugiyama | MAPKAPK3 | KLTDFGFAKEttQNALQtPCytPYYVAPEVLGPEKYDKSCD |
| Q16832 | S65 | Sugiyama | DDR2 NTRKR3 TKT TYRO10 | DITASSQWSESTAAKYGRLDsEEGDGAWCPEIPVEPDDLKE |
| Q32P51 | S95 | Sugiyama | HNRNPA1L2 HNRNPA1L | TPHKVDGRVVEPKRAVsREDsQRPGAHLtVKKIFVGGIKED |
| Q3MII6 | S506 | Sugiyama | TBC1D25 OATL1 | DHLATASQGPGGGGRLLRQAsLDGLQQLRDNMGSRRDPLVQ |
| Q3SY84 | S143 | Sugiyama | KRT71 K6IRS1 KB34 KRT6IRS1 | IQKVRAQEREQIKALNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q53EL6 | S68 | Sugiyama | PDCD4 H731 | ssINEARINAKAKRRLRKNssRDsGRGDsVsDsGsDALRSG |
| Q53EL6 | S76 | Sugiyama | PDCD4 H731 | NAKAKRRLRKNssRDsGRGDsVsDsGsDALRSGLtVPtsPK |
| Q562R1 | S240 | Sugiyama | ACTBL2 | VALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPE |
| Q562R1 | Y241 | Sugiyama | ACTBL2 | ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA |
| Q58FF7 | S408 | Sugiyama | HSP90AB3P HSP90BC | EPIDEYCVQQLKEFDGKsLVsVtKEGLELPEDEEEKKKMEE |
| Q58FF8 | S308 | Sugiyama | HSP90AB2P HSP90BB | YMTEPIDGYQLKEFDGKsLVsVtKEGLELPEDGEEKKRMEE |
| Q5JTD0 | S361 | Sugiyama | TJAP1 PILT TJP4 | IPRNsPLPNCtyAtRQAISLsLVEEGSERARPSPVPSTPAS |
| Q5SW79 | S861 | Sugiyama | CEP170 FAM68A KAB KIAA0470 | IEKPsPNIPIELIPHINKQTsstPssLALtsAsRIRERsEs |
| Q5SW79 | S881 | Sugiyama | CEP170 FAM68A KAB KIAA0470 | sstPssLALtsAsRIRERsEsLDPDssMDTtLILKDTEAVM |
| Q5SYE7 | S1495 | Sugiyama | NHSL1 C6orf63 KIAA1357 | KNRRAQEEWAKNEGLMPRsLsFsGPRYGRSRTPPSAASSRY |
| Q5T035 | S66 | Sugiyama | FAM120A2P C9orf129 | LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERSLPI |
| Q5T6F2 | S439 | Sugiyama | UBAP2 KIAA1491 | VLSHLDFKsQPEPsPVLSQLsQRQQHQSQAVTVPPPGLESF |
| Q5XKE5 | S155 | Sugiyama | KRT79 K6L KB38 KRT6L | IQRVRTQEREQIKTLNNKFAsFIDKVRFLEQQNKVLETKWA |
| Q63ZY3 | S356 | Sugiyama | KANK2 ANKRD25 KIAA1518 MXRA3 SIP | PREVEVVASTAAGAPAQRAQsLEPYGtGLRALAMPGRPEsP |
| Q66K14 | S1238 | Sugiyama | TBC1D9B KIAA0676 | EKRVDIGLKIKDQKKVERQFstAsDHEQPGVsG________ |
| Q6GYQ0 | S797 | Sugiyama | RALGAPA1 GARNL1 KIAA0884 TULIP1 | EtGNEVFGALNEEQPLPRssstsDILEPFTVERAKVNKEDM |
| Q6JBY9 | S179 | GPS6|SIGNOR|EPSD | RCSD1 CAPZIP | VRTRGSIKRRPPSRRFRRsQsDCGELGDFRAVESSQQNGAK |
| Q6JBY9 | S244 | GPS6|SIGNOR | RCSD1 CAPZIP | AGEGVRTLGPAEKPPLRRSPsRTEKQEEDRATEEAKNGEKA |
| Q6PEY2 | S54 | Sugiyama | TUBA3E | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q6S8J3 | S1068 | Sugiyama | POTEE A26C1A POTE2 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q6S8J3 | S939 | Sugiyama | POTEE A26C1A POTE2 | VALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPE |
| Q6S8J3 | Y940 | Sugiyama | POTEE A26C1A POTE2 | ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA |
| Q6UVK1 | S1857 | Sugiyama | CSPG4 MCSP | ASVPLRLTRGSRAPISRAQLsVVDPDSAPGEIEyEVQRAPH |
| Q6VN20 | S361 | Sugiyama | RANBP10 KIAA1464 | VNGTDSEVRSLSSRsPKsQDsyPGsPsLsPRHGPsssHMHN |
| Q6VY07 | S528 | Sugiyama | PACS1 KIAA1175 | KRSTPLKERQLsKPLsERtNssDsERsPDLGHsTQIPRKVV |
| Q6ZMR3 | S161 | Sugiyama | LDHAL6A LDHL2 | DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH |
| Q71U36 | S54 | Sugiyama | TUBA1A TUBA3 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q7KZF4 | S645 | Sugiyama | SND1 TDRD11 | HALSKVHFTAERSSYYKSLLsAEEAAKQKKEKVWAHyEEQP |
| Q7RTS7 | S153 | Sugiyama | KRT74 K6IRS4 KB37 KRT5C KRT6IRS4 | IQKVRAQEREQIKVLNDKFAsFIDKVRFLEQQNQVLETKWE |
| Q7Z3J3 | T1210 | Sugiyama | RGPD4 RGP4 | KLIQRAEEMKSGLKDFKTFLtNDQTKVTEEENKGsGtGAAG |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q7Z5L9 | S457 | Sugiyama | IRF2BP2 | GSHASKDANQVHSTTRRNsNsPPsPssMNQRRLGPREVGGQ |
| Q7Z794 | S177 | Sugiyama | KRT77 KRT1B | IQRIKTQEREQIMVLNNKFAsFIDKVRFLEQQNQVLQTKWE |
| Q86U86 | S948 | Sugiyama | PBRM1 BAF180 PB1 | AEKsEDssGAAGLSGLHRtYsQDCsFKNSMYHVGDYVYVEP |
| Q86UE4 | S298 | Sugiyama | MTDH AEG1 LYRIC | NLTVNGGGWNEKSVKLssQIsAGEEKWNsVsPAsAGKRKtE |
| Q86UF2 | S140 | Sugiyama | CTAGE6 CTAGE6P | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q86UP2 | S722 | Sugiyama | KTN1 CG1 KIAA0004 | ILNDQNKALKSEVQKLQTLVsEQPNKDVVEQMEKCIQEKDE |
| Q86VQ1 | S223 | Sugiyama | GLCCI1 | QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR |
| Q86Y46 | S145 | Sugiyama | KRT73 K6IRS3 KB36 KRT6IRS3 | IQKVRAQEREQIKVLNNKFAsFIDKVRFLEQQNQVLETKWE |
| Q8IUD2 | S250 | Sugiyama | ERC1 ELKS KIAA1081 RAB6IP2 | QALQDELRIQRDLNQLFQQDsssRTGEPCVAELTEENFQRL |
| Q8IWX8 | S904 | Sugiyama | CHERP DAN26 SCAF6 | KGVGVALDDPyENyRRNKsysFIARMKARDECK________ |
| Q8IX94 | S140 | Sugiyama | CTAGE4 | AAAEEARSLEATCEKLNRsNsELEDEILCLEKDLKEEKSKH |
| Q8IXW5 | S352 | Sugiyama | RPAP2 C1orf82 | KSAEHFKRKFAKSNQVSRsVsSSVQVCPEVGKRNLLKVLKE |
| Q8N5C8 | S506 | GPS6|EPSD|PSP | TAB3 MAP3K7IP3 | ISVIPGsGGEKGSHKYQRssssGsDDyAyTQALLLHQRARM |
| Q8N684 | S166 | Sugiyama | CPSF7 | PGKVLNGEKVDVRPAtRQNLsQFEAQARKRECVRVPRGGIP |
| Q8N8S7 | S125 | Sugiyama | ENAH MENA | MHALEVLNSQETGPTLPRQNsQLPAQVQNGPSQEELEIQRR |
| Q8NBJ7 | S256 | Sugiyama | SUMF2 PSEC0171 UNQ1968/PRO4500 | EWTASPYQAAEQDMRVLRGAsWIDtADGsANHRARVttRMG |
| Q8NBS9 | S426 | Sugiyama | TXNDC5 TLP46 UNQ364/PRO700 | KKVSEHSGGRDLDSLHRFVLsQAKDEL______________ |
| Q8NFH8 | S631 | Sugiyama | REPS2 POB1 | AIQTAIRKNKEANAVLARLNsELQQQLKEVHQERIALENQL |
| Q8NFI4 | S181 | Sugiyama | ST13P5 FAM10A5 | LQKPNAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEA |
| Q8NHG7 | S46 | Sugiyama | SVIP | AEAAERRQKEAASRGILDVQsVQEKRKKKEKIEKQIATsGP |
| Q8NI08 | S208 | Sugiyama | NCOA7 ERAP140 ESNA1 Nbla00052 Nbla10993 | DKLPDADLARKALKPIERVLsstsEEDEPGVVKFLKMNCRY |
| Q8NI08 | S441 | Sugiyama | NCOA7 ERAP140 ESNA1 Nbla00052 Nbla10993 | ELSsQTGGGMHKKDTLKECLsLDPEERKKAESQINNSAVEM |
| Q8TBC4 | S420 | Sugiyama | UBA3 UBE1C | PAItATLEGKNRTLYLQsVTsIEERTRPNLSKTLKELGLVD |
| Q8WUA4 | S378 | Sugiyama | GTF3C2 KIAA0011 | FSVQREGLPEDGtLYRINRFssITAHPERWDVSFFTGGPLW |
| Q8WUA4 | S379 | Sugiyama | GTF3C2 KIAA0011 | SVQREGLPEDGtLYRINRFssITAHPERWDVSFFTGGPLWA |
| Q8WUI4 | S486 | Sugiyama | HDAC7 HDAC7A | GDtVLLPLAQGGHRPLsRAQssPAAPAsLSAPEPASQARVL |
| Q8WUM4 | S557 | Sugiyama | PDCD6IP AIP1 ALIX KIAA1375 | ANPAKTMQGSEVVNVLKSLLsNLDEVKKEREGLENDLKSVN |
| Q8WVV9 | S61 | Sugiyama | HNRNPLL HNRPLL SRRF BLOCK24 | NRREAtPRGGGDGGGGGRsFsQPEAGGsHHKVsVsPVVHVR |
| Q8WX93 | S479 | Sugiyama | PALLD KIAA0992 CGI-151 | VLECRVRGAPPLQVQWFRQGsEIQDsPDFRILQKKPRSTAE |
| Q8WXH0 | S2781 | Sugiyama | SYNE2 KIAA1011 NUA | ILSQIRKCKVTHDGILARQQsVEsLAEEVKDKVPSLTTYEG |
| Q92597 | T328 | Sugiyama | NDRG1 CAP43 DRG1 RTP | FVQGMGYMPsAsMtRLMRsRtAsGssVtsLDGtRsRsHtSE |
| Q92688 | S117 | Sugiyama | ANP32B APRIL PHAPI2 | GNKLKDIstLEPLKKLECLKsLDLFNCEVtNLNDyREsVFK |
| Q92945 | S193 | Sugiyama | KHSRP FUBP2 | DSGCKVQIsPDsGGLPERsVsLtGAPEsVQKAKMMLDDIVS |
| Q96B36 | S212 | Sugiyama | AKT1S1 PRAS40 | GFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAED |
| Q96BY7 | S497 | Sugiyama | ATG2B C14orf103 | PSNLVHPTPLQKtsLPsRsVsVDESRPELIFRLAVGTFSIS |
| Q96C19 | S74 | Sugiyama | EFHD2 SWS1 | ELSAKLLRRADLNQGIGEPQsPsRRVFNPytEFKEFSRKQI |
| Q96D71 | S767 | Sugiyama | REPS1 | AIQAsIRRNKETNTVLARLNsELQQQLKDVLEERISLEVQL |
| Q96E11 | S239 | Sugiyama | MRRF | LKKSKDTVsEDtIRLIEKQIsQMADDtVAELDRHLAVKTKE |
| Q96EK9 | T157 | Sugiyama | KTI12 SBBI81 | RAEEDGRAQAAGSSVLRELHtADSVVNGSAQADVPKELERE |
| Q96G46 | S236 | Sugiyama | DUS3L | QQLRKREVRFERAEQALRRFsQGPtPAAAVPEGTAAEGAPR |
| Q96MH2 | S194 | Sugiyama | HEXIM2 L3 | EAGDSDGRGRAHGEFQRKDFsEtYERFHTESLQGRSKQELV |
| Q96PK6 | S521 | Sugiyama | RBM14 SIP | AAAYGAQPSATLAAPYRtQssAsLAAsYAAQQHPQAAASYR |
| Q96S55 | T116 | Sugiyama | WRNIP1 WHIP | GEEGDDGGETESREsyDAPPtPsGARLIPDFPVARsssPGR |
| Q96T51 | S319 | Sugiyama | RUFY1 RABIP4 ZFYVE12 | ERITDVLDQKNYVEELNRHLsCTVGDLQTKIDGLEKTNSKL |
| Q99543 | S275 | Sugiyama | DNAJC2 MPHOSPH11 MPP11 ZRF1 | RAQRKKEEMNRIRtLVDNAysCDPRIKKFKEEEKAKKEAEK |
| Q99575 | S816 | Sugiyama | POP1 KIAA0061 | VAATGSHLCVLRSRKLLKQLsAWCGPSSEDSRGGRRAPGRG |
| Q99613 | S865 | Sugiyama | EIF3C EIF3S8 | HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF |
| Q99615 | S207 | Sugiyama | DNAJC7 TPR2 TTC2 | AMLGRYPEAQSVASDILRMDsTNADALYVRGLCLYYEDCIE |
| Q99618 | S94 | Sugiyama | CDCA3 C8 GRCC8 TOME1 | ARtPMKTSsGDPPsPLVKQLsEVFETEDSKSNLPPEPVLPP |
| Q99666 | T1209 | Sugiyama | RGPD5 RANBP2L1 RGP5 RGP7 RGPD7; RGPD6 RANBP2L2 RGP6 | KLIQRAEEMKSGLKDFKTFLtNDQTKVTEEENKGsGtGAAG |
| Q9BQE3 | S54 | Sugiyama | TUBA1C TUBA6 | GQMPSDKtIGGGDDsFNtFFsEtGAGKHVPRAVFVDLEPtV |
| Q9BQS8 | S425 | Sugiyama | FYCO1 ZFYVE7 | EKLQALERERTKVEEVNRQQsAQLEQLVKELQLKEDARASL |
| Q9BTE6 | S174 | Sugiyama | AARSD1 | IEQSVNEKIRDRLPVNVRELsLDDPEVEQVsGRGLPDDHAG |
| Q9BUP3 | S177 | Sugiyama | HTATIP2 CC3 TIP30 | LKFDRYSVFRPGVLLCDRQEsRPGEWLVRKFFGSLPDSWAS |
| Q9BVC4 | S43 | Sugiyama | MLST8 GBL LST8 | TVRFWQAHSGICTRTVQHQDsQVNALEVTPDRSMIAAAGYQ |
| Q9BW27 | S652 | Sugiyama | NUP85 NUP75 PCNT1 | VEMLRLSLARNLARAIIREGsLEGS________________ |
| Q9BXP5 | S422 | Sugiyama | SRRT ARS2 ASR2 | EKPKDAAGLECKPRPLHKTCsLFMRNIAPNISRAEIIsLCK |
| Q9BYX7 | S239 | Sugiyama | POTEKP ACTBL3 FKSG30 | VALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPE |
| Q9BYX7 | S368 | Sugiyama | POTEKP ACTBL3 FKSG30 | SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________ |
| Q9BYX7 | Y240 | Sugiyama | POTEKP ACTBL3 FKSG30 | ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA |
| Q9BZD4 | S171 | Sugiyama | NUF2 CDCA1 NUF2R | KMQQLNAAHQEALMKLERLDsVPVEEQEEFKQLSDGIQELQ |
| Q9BZG1 | S241 | Sugiyama | RAB34 RAB39 RAH | VLAELEKSGARRIGDVVRINsDDsNLyLTASKKKPTCCP__ |
| Q9C0C2 | S221 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | TyGtTTAPRDEDGstLFRGWsQEGPVKsPAECREEHsKtPE |
| Q9C0C2 | S429 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | EEEAKGDAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAA |
| Q9C0C9 | S399 | Sugiyama | UBE2O KIAA1734 | EGsMAKKVKRLLKKQVVRIMsCsPDtQCsRDHsMEDPDKKG |
| Q9GZZ9 | S45 | Sugiyama | UBA5 UBE1DC1 | LQVPRSGDGGGGRVRIEKMssEVVDSNPysRLMALKRMGIV |
| Q9H078 | S155 | Sugiyama | CLPB SKD3 | DAALLEAARANNMQEVSRLLsEGADVNAKHRLGWTALMVAA |
| Q9H2U2 | S309 | Sugiyama | PPA2 HSPC124 | NCTNVQISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVW |
| Q9H2U2 | S315 | Sugiyama | PPA2 HSPC124 | ISDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK_ |
| Q9H2U2 | S316 | Sugiyama | PPA2 HSPC124 | SDSPFRCtQEEARsLVEsVsssPNKEsNEEEQVWHFLGK__ |
| Q9H3N1 | S270 | Sugiyama | TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268 | EAEsKEGtNKDFPQNAIRQRsLGPsLAtDKs__________ |
| Q9H410 | S125 | Sugiyama | DSN1 C20orf172 MIS13 | NRRKsLHPIHQGITELSRsIsVDLAESKRLGCLLLSSFQFS |
| Q9H4L5 | S437 | Sugiyama | OSBPL3 KIAA0704 ORP3 OSBP3 | GDNLAEENsRDENRALVHQLsNESRLSITDSLSEFFDAQEV |
| Q9H788 | S315 | Sugiyama | SH2D4A PPP1R38 SH2A | LNSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRA |
| Q9H788 | S316 | Sugiyama | SH2D4A PPP1R38 SH2A | NSGAYPQKPLRNQGVVRtLsssAQEDIIRWFKEEQLPLRAG |
| Q9H814 | S298 | Sugiyama | PHAX RNUXA | NGSRRRTPGGVFLNLLKNtPsISEEQIKDIFyIENQKEYEN |
| Q9NQW6 | S225 | Sugiyama | ANLN | LAATICsWEDDVNHsFAKQNsVQEQPGTACLSKFSSASGAs |
| Q9NR30 | S706 | Sugiyama | DDX21 | PTASVTEIQEKWHDSRRWQLsVATEQPELEGPREGYGGFRG |
| Q9NSB2 | S178 | Sugiyama | KRT84 KRTHB4 | AQRVKKDEKEQIKTLNNKFAsFIDKVRFLEQQNKLLETKWS |
| Q9NY33 | S218 | Sugiyama | DPP3 | tRLFKEVDGEGKPYYEVRLAsVLGSEPsLDsEVTSKLKSYE |
| Q9NY33 | S225 | Sugiyama | DPP3 | DGEGKPYYEVRLAsVLGSEPsLDsEVTSKLKSYEFRGsPFQ |
| Q9NZB2 | S417 | Sugiyama | FAM120A C9orf10 KIAA0183 OSSA | LSEPAPLTLDTSGKNLtEQNsysNIPHEGKHtPLyERssPI |
| Q9UBR2 | S78 | Sugiyama | CTSZ | SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST |
| Q9UGV2 | S331 | Sugiyama | NDRG3 | QGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQ |
| Q9UGV2 | T329 | Sugiyama | NDRG3 | FLQGMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVts |
| Q9UGV2 | T332 | Sugiyama | NDRG3 | GMGYIPSASMTRLARsRtHstsssLGsGEsPFsRsVtsNQs |
| Q9UHB6 | S283 | Sugiyama | LIMA1 EPLIN SREBP3 PP624 | sEtsIKDRMAKYQAAVSKQSsSTNyTNELKASGGEIKIHKM |
| Q9UHD2 | S510 | Sugiyama | TBK1 NAK | LEAAELGEISDIHTKLLRLsssQGTIETSLQDIDSRLsPGG |
| Q9UHI6 | S268 | Sugiyama | DDX20 DP103 GEMIN3 | EFLANALTKYMRDPTFVRLNsSDPSLIGLKQYYKVVNSYPL |
| Q9UHX1 | S461 | Sugiyama | PUF60 FIR ROBPI SIAHBP1 | sIsGssARHMVMQKLLRKQEsTVMVLRNMVDPKDIDDDLEG |
| Q9UI15 | S185 | Sugiyama | TAGLN3 NP25 | EQLRQGQNVIGLQMGSNKGAsQAGMtGyGMPRQIM______ |
| Q9UII2 | S63 | Sugiyama | ATP5IF1 ATPI ATPIF1 | AGGAFGKREQAEEERyFRAQsREQLAALKKHHEEEIVHHKK |
| Q9UJ70 | S76 | Sugiyama | NAGK | AKRKAGVDPLVPLRsLGLsLsGGDQEDAGRILIEELRDRFP |
| Q9UK23 | S145 | Sugiyama | NAGPA | ETARAADCRVAQNGGFFRMNsGECLGNVVSDERRVSSSGGL |
| Q9UK23 | S319 | Sugiyama | NAGPA | LASYPSDHCQDNMWRCPRQVsTVVCVHEPRCQPPDCHGHGT |
| Q9UKT5 | S48 | Sugiyama | FBXO4 FBX4 | LSGWKTFWQSVSKERVARttsREEVDEAASTLTRLPIDVQL |
| Q9UKV8 | S387 | Sugiyama | AGO2 EIF2C2 | ATARSAPDRQEEISKLMRsAsFNTDPyVREFGIMVKDEMTD |
| Q9ULD2 | S1203 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | QENEELKARMDKHMAISRQLstEQAVLQESLEKESKVNKRL |
| Q9ULD2 | T1204 | Sugiyama | MTUS1 ATBP ATIP GK1 KIAA1288 MTSG1 | ENEELKARMDKHMAISRQLstEQAVLQESLEKESKVNKRLs |
| Q9UMX5 | T48 | Sugiyama | NENF CIR2 SPUF | TARAGQTPRPAERGPPVRLFtEEELARYGGEEEDQPIyLAV |
| Q9UN36 | S338 | Sugiyama | NDRG2 KIAA1248 SYLD | ASSCMTRLsRsRtAsLtsAAsVDGNRsRsRtLsQssEsGtL |
| Q9UNH7 | S314 | Sugiyama | SNX6 | DLLKYYLRESQAAKDLLYRRsRsLVDYENANKALDKARAKN |
| Q9UNH7 | S316 | Sugiyama | SNX6 | LKYYLRESQAAKDLLYRRsRsLVDYENANKALDKARAKNKD |
| Q9UNZ2 | S176 | Sugiyama | NSFL1C UBXN2C | RLGAAPEEEsAyVAGEKRQHssQDVHVVLKLWKsGFsLDNG |
| Q9UNZ2 | S192 | Sugiyama | NSFL1C UBXN2C | KRQHssQDVHVVLKLWKsGFsLDNGELRSyQDPsNAQFLEs |
| Q9UPN3 | S2769 | Sugiyama | MACF1 ABP620 ACF7 KIAA0465 KIAA0754 KIAA1251 | EAIEKRLISPELANMIQIDSsEFSDHRAQIEKQEGIEVCAL |
| Q9UPQ0 | S299 | Sugiyama | LIMCH1 KIAA1102 | yVPAPLRKKKAEREEYRKsWstAtsPLGGERPFRYGPRtPV |
| Q9UPQ0 | S303 | Sugiyama | LIMCH1 KIAA1102 | PLRKKKAEREEYRKsWstAtsPLGGERPFRYGPRtPVSDDA |
| Q9UPQ0 | S379 | Sugiyama | LIMCH1 KIAA1102 | EEDDKWQDDLARWKSRRRsVsQDLIKKEEERKKMEKLLAGE |
| Q9UQ35 | S2692 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | ERRSRSPRKPIDsLRDsRsLsysPVERRRPsPQPsPRDQQS |
| Q9UQ35 | S435 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | ssssEssPPsPQPTKVsRHAsssPEsPKPAPAPGsHREIss |
| Q9UQ80 | S267 | Sugiyama | PA2G4 EBP1 | YKRDPSKQYGLKMKtSRAFFsEVERRFDAMPFtLRAFEDEK |
| Q9UQ80 | S335 | Sugiyama | PA2G4 EBP1 | FVAQFKFTVLLMPNGPMRITsGPFEPDLyKsEMEVQDAELK |
| Q9Y266 | S259 | Sugiyama | NUDC | KVVTVHLEKINKMEWWSRLVssDPEINtKKINPENsKLsDL |
| Q9Y2B0 | S65 | Sugiyama | CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 | VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI |
| Q9Y2T3 | S263 | Sugiyama | GDA KIAA1258 | ENRDEVEAVKNLYPSYKNYTsVYDKNNLLTNKTVMAHGCYL |
| Q9Y2U5 | S239 | Sugiyama | MAP3K2 MAPKKK2 MEKK2 | SLDSPLDGESYPKSRMPRAQsyPDNHQEFSDyDNPIFEKFG |
| Q9Y2X7 | S592 | Sugiyama | GIT1 | PLLsCsQEGsRHtsKLsRHGsGADsDyENtQSGDPLLGLEG |
| Q9Y3B8 | S203 | Sugiyama | REXO2 SFN SMFN CGI-114 | EYEFAPKKAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKK |
| Q9Y4E8 | S170 | Sugiyama | USP15 KIAA0529 | RRFSKADTIDTIEKEIRKIFsIPDEKETRLWNKYMSNTFEP |
| Q9Y4P3 | T433 | Sugiyama | TBL2 WBSCR13 UNQ563/PRO1125 | QGHLKRASNESTRQRLQQQLtQAQETLKSLGALKK______ |
| Q9Y4X5 | S514 | Sugiyama | ARIH1 ARI MOP6 UBCH7BP HUSSY-27 | NQADLENATEVLSGYLERDIsQDsLQDIKQKVQDKYRYCES |
| Q9Y580 | S136 | Sugiyama | RBM7 | RyERTMDNMTSSAQIIQRsFssPENFQRQAVMNsALRQMSY |
| Q9Y5B9 | S650 | Sugiyama | SUPT16H FACT140 FACTP140 | KRYKTREAEEKEKEGIVKQDsLVINLNRsNPKLKDLYIRPN |
| Q9Y5S9 | S56 | Sugiyama | RBM8A RBM8 HSPC114 MDS014 | KGRGFGsEEGsRARMREDyDsVEQDGDEPGPQRSVEGWILF |
| Q9Y5U2 | S86 | Sugiyama | TSSC4 | PSPPSGLLPATVQPFHLRGMssTFSQRsRDIFDCLEGAARR |
| Q9Y697 | S283 | Sugiyama | NFS1 NIFS HUSSY-08 | KGVGAIYIRRRPRVRVEALQsGGGQERGMRsGTVPTPLVVG |
| Q9Y6D9 | S485 | Sugiyama | MAD1L1 MAD1 TXBP181 | GQKQRADMLEMELKMLKSQSsSAEQsFLFSREEADTLRLKV |
| Q9Y6G9 | S516 | Sugiyama | DYNC1LI1 DNCLI1 | HAELDRITRKPVtVsPttPtsPtEGEAs_____________ |
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| NRAGE signals death through JNK | R-HSA-193648 | 1.121642e-07 | 6.950 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 8.379833e-07 | 6.077 | 0 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.540158e-06 | 5.812 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 3.067152e-06 | 5.513 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 3.578695e-06 | 5.446 | 1 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 1.980536e-05 | 4.703 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 2.409423e-05 | 4.618 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 2.409423e-05 | 4.618 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 4.097880e-05 | 4.387 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 5.689517e-05 | 4.245 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 6.045297e-05 | 4.219 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 8.823962e-05 | 4.054 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 1.578462e-04 | 3.802 | 0 | 0 |
| Neurodegenerative Diseases | R-HSA-8863678 | 1.578462e-04 | 3.802 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 2.036875e-04 | 3.691 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 3.582051e-04 | 3.446 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 3.873638e-04 | 3.412 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 4.262659e-04 | 3.370 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 4.753261e-04 | 3.323 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 4.753261e-04 | 3.323 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 5.066204e-04 | 3.295 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 4.745628e-04 | 3.324 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 5.066204e-04 | 3.295 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 5.835539e-04 | 3.234 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 7.013031e-04 | 3.154 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 7.635992e-04 | 3.117 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 8.067104e-04 | 3.093 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 8.067104e-04 | 3.093 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 7.831355e-04 | 3.106 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 8.067104e-04 | 3.093 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 8.455932e-04 | 3.073 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 9.657893e-04 | 3.015 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 1.076071e-03 | 2.968 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 1.078856e-03 | 2.967 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 1.633542e-03 | 2.787 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.598391e-03 | 2.796 | 0 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 1.924822e-03 | 2.716 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 2.188486e-03 | 2.660 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 2.265582e-03 | 2.645 | 0 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 2.313457e-03 | 2.636 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 2.358317e-03 | 2.627 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 2.500670e-03 | 2.602 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 2.634982e-03 | 2.579 | 1 | 1 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 3.139511e-03 | 2.503 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 3.154335e-03 | 2.501 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 3.217865e-03 | 2.492 | 0 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 3.295458e-03 | 2.482 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 3.690942e-03 | 2.433 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 3.884063e-03 | 2.411 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 3.960040e-03 | 2.402 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 3.990213e-03 | 2.399 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 4.436728e-03 | 2.353 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 4.704624e-03 | 2.327 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 4.717406e-03 | 2.326 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 4.743657e-03 | 2.324 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 4.840268e-03 | 2.315 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 5.137195e-03 | 2.289 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 5.149387e-03 | 2.288 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 5.149387e-03 | 2.288 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 5.475462e-03 | 2.262 | 0 | 0 |
| Cell Cycle | R-HSA-1640170 | 5.525203e-03 | 2.258 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 6.915677e-03 | 2.160 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 6.727995e-03 | 2.172 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 7.010633e-03 | 2.154 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 7.808445e-03 | 2.107 | 1 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 7.661098e-03 | 2.116 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 7.911809e-03 | 2.102 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 7.921244e-03 | 2.101 | 0 | 0 |
| M Phase | R-HSA-68886 | 7.953915e-03 | 2.099 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 8.290584e-03 | 2.081 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 8.524158e-03 | 2.069 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 9.312458e-03 | 2.031 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 9.315842e-03 | 2.031 | 0 | 0 |
| PKA activation | R-HSA-163615 | 9.819270e-03 | 2.008 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 9.819270e-03 | 2.008 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 9.819270e-03 | 2.008 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 9.614855e-03 | 2.017 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 1.102251e-02 | 1.958 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 1.114265e-02 | 1.953 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 1.120516e-02 | 1.951 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 1.258737e-02 | 1.900 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 1.258737e-02 | 1.900 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 1.239920e-02 | 1.907 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 1.213055e-02 | 1.916 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 1.469798e-02 | 1.833 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 1.469798e-02 | 1.833 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 1.469798e-02 | 1.833 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 1.469798e-02 | 1.833 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 1.330538e-02 | 1.876 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 1.436679e-02 | 1.843 | 0 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 1.370035e-02 | 1.863 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 1.504162e-02 | 1.823 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 1.516413e-02 | 1.819 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 1.526030e-02 | 1.816 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 1.713070e-02 | 1.766 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 1.858841e-02 | 1.731 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 1.772652e-02 | 1.751 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 1.864104e-02 | 1.730 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 1.884458e-02 | 1.725 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 1.899736e-02 | 1.721 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.913843e-02 | 1.718 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 1.913843e-02 | 1.718 | 0 | 0 |
| Signaling by MAPK mutants | R-HSA-9652817 | 1.948339e-02 | 1.710 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 2.066872e-02 | 1.685 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.948339e-02 | 1.710 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 2.056024e-02 | 1.687 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 2.083925e-02 | 1.681 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 2.109338e-02 | 1.676 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 2.223167e-02 | 1.653 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 2.223167e-02 | 1.653 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 2.206712e-02 | 1.656 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 2.206712e-02 | 1.656 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 2.206712e-02 | 1.656 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 2.232015e-02 | 1.651 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 2.206712e-02 | 1.656 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 2.223086e-02 | 1.653 | 0 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 2.330274e-02 | 1.633 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 2.419388e-02 | 1.616 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 2.595475e-02 | 1.586 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 2.619358e-02 | 1.582 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 2.833027e-02 | 1.548 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 2.638433e-02 | 1.579 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 2.825305e-02 | 1.549 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 2.833027e-02 | 1.548 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 2.833027e-02 | 1.548 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 2.859156e-02 | 1.544 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 2.859156e-02 | 1.544 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.859156e-02 | 1.544 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 2.859156e-02 | 1.544 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 3.156268e-02 | 1.501 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 3.034128e-02 | 1.518 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 3.330199e-02 | 1.478 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 3.224892e-02 | 1.491 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 3.224892e-02 | 1.491 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 3.469697e-02 | 1.460 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 3.486787e-02 | 1.458 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 3.529262e-02 | 1.452 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 3.529262e-02 | 1.452 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 3.529262e-02 | 1.452 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 3.529262e-02 | 1.452 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 3.549155e-02 | 1.450 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 4.132654e-02 | 1.384 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 4.132654e-02 | 1.384 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 4.132654e-02 | 1.384 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 3.921713e-02 | 1.407 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 4.074477e-02 | 1.390 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 4.040003e-02 | 1.394 | 0 | 0 |
| Transcriptional activation of cell cycle inhibitor p21 | R-HSA-69895 | 4.132654e-02 | 1.384 | 0 | 0 |
| Transcriptional activation of p53 responsive genes | R-HSA-69560 | 4.132654e-02 | 1.384 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of cell cycle factors | R-HSA-8866911 | 4.132654e-02 | 1.384 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 3.899737e-02 | 1.409 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 4.062501e-02 | 1.391 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 3.764254e-02 | 1.424 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 4.155798e-02 | 1.381 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 4.160942e-02 | 1.381 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 4.280469e-02 | 1.369 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 4.327122e-02 | 1.364 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 4.327122e-02 | 1.364 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 4.335192e-02 | 1.363 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest | R-HSA-6804116 | 4.335192e-02 | 1.363 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 4.451374e-02 | 1.352 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 4.473039e-02 | 1.349 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 4.473039e-02 | 1.349 | 0 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 5.217530e-02 | 1.283 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 5.217530e-02 | 1.283 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 5.010464e-02 | 1.300 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 4.967830e-02 | 1.304 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 5.269368e-02 | 1.278 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 4.953361e-02 | 1.305 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 5.010464e-02 | 1.300 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 5.401350e-02 | 1.267 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 5.019665e-02 | 1.299 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 5.217530e-02 | 1.283 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 5.217530e-02 | 1.283 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 5.411083e-02 | 1.267 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 5.411083e-02 | 1.267 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 5.411083e-02 | 1.267 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 5.411083e-02 | 1.267 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 5.411083e-02 | 1.267 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 5.411083e-02 | 1.267 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 5.411083e-02 | 1.267 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 5.505054e-02 | 1.259 | 0 | 0 |
| TWIK-releated acid-sensitive K+ channel (TASK) | R-HSA-1299316 | 5.578668e-02 | 1.253 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 5.578668e-02 | 1.253 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 5.595065e-02 | 1.252 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 5.615094e-02 | 1.251 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 5.615094e-02 | 1.251 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 5.766406e-02 | 1.239 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 5.796310e-02 | 1.237 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 5.913997e-02 | 1.228 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 5.995820e-02 | 1.222 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 6.718390e-02 | 1.173 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 6.743903e-02 | 1.171 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 6.254584e-02 | 1.204 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 6.254584e-02 | 1.204 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 7.049348e-02 | 1.152 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 7.049348e-02 | 1.152 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 6.718390e-02 | 1.173 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 6.638295e-02 | 1.178 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 6.300146e-02 | 1.201 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 7.049348e-02 | 1.152 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 6.254584e-02 | 1.204 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 7.065976e-02 | 1.151 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 7.065976e-02 | 1.151 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 7.094425e-02 | 1.149 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 7.094425e-02 | 1.149 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 7.152468e-02 | 1.146 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 7.179669e-02 | 1.144 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 7.237999e-02 | 1.140 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 7.270776e-02 | 1.138 | 1 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 7.398186e-02 | 1.131 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 7.398186e-02 | 1.131 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 7.855904e-02 | 1.105 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 7.931278e-02 | 1.101 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.007407e-02 | 1.097 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 8.007407e-02 | 1.097 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 8.031025e-02 | 1.095 | 0 | 0 |
| GLI proteins bind promoters of Hh responsive genes to promote transcription | R-HSA-5635851 | 8.182724e-02 | 1.087 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 8.182724e-02 | 1.087 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 8.182724e-02 | 1.087 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 8.182724e-02 | 1.087 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 8.260566e-02 | 1.083 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 8.417668e-02 | 1.075 | 0 | 0 |
| Regulation of cortical dendrite branching | R-HSA-8985801 | 9.147803e-02 | 1.039 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 9.875495e-02 | 1.005 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 8.726783e-02 | 1.059 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 8.726783e-02 | 1.059 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 9.514988e-02 | 1.022 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 8.743964e-02 | 1.058 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 9.633302e-02 | 1.016 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 9.980626e-02 | 1.001 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 9.709141e-02 | 1.013 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 9.103371e-02 | 1.041 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 9.980626e-02 | 1.001 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 8.854543e-02 | 1.053 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 8.954148e-02 | 1.048 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 1.012328e-01 | 0.995 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.024291e-01 | 0.990 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 1.029294e-01 | 0.987 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 1.030493e-01 | 0.987 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 1.030493e-01 | 0.987 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 1.030493e-01 | 0.987 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 1.030493e-01 | 0.987 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 1.043918e-01 | 0.981 | 0 | 0 |
| Defective translocation of RB1 mutants to the nucleus | R-HSA-9661070 | 1.184446e-01 | 0.926 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 1.184446e-01 | 0.926 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 2.228661e-01 | 0.652 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 2.228661e-01 | 0.652 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 2.228661e-01 | 0.652 | 0 | 0 |
| Impaired BRCA2 translocation to the nucleus | R-HSA-9709275 | 2.228661e-01 | 0.652 | 0 | 0 |
| Defective DNA double strand break response due to BRCA1 loss of function | R-HSA-9663199 | 2.228661e-01 | 0.652 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 2.228661e-01 | 0.652 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 2.228661e-01 | 0.652 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 2.228661e-01 | 0.652 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 2.228661e-01 | 0.652 | 0 | 0 |
| Impaired BRCA2 binding to SEM1 (DSS1) | R-HSA-9763198 | 2.228661e-01 | 0.652 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 2.228661e-01 | 0.652 | 0 | 0 |
| Defective DNA double strand break response due to BARD1 loss of function | R-HSA-9699150 | 2.228661e-01 | 0.652 | 0 | 0 |
| Activation of BIM and translocation to mitochondria | R-HSA-111446 | 1.319626e-01 | 0.880 | 0 | 0 |
| HCN channels | R-HSA-1296061 | 1.756053e-01 | 0.755 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 1.756053e-01 | 0.755 | 0 | 0 |
| FBXW7 Mutants and NOTCH1 in Cancer | R-HSA-2644605 | 1.756053e-01 | 0.755 | 0 | 0 |
| Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling | R-HSA-2644607 | 1.756053e-01 | 0.755 | 0 | 0 |
| FGFR4 mutant receptor activation | R-HSA-1839128 | 3.149241e-01 | 0.502 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 3.149241e-01 | 0.502 | 0 | 0 |
| PI and PC transport between ER and Golgi membranes | R-HSA-1483196 | 3.149241e-01 | 0.502 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 3.149241e-01 | 0.502 | 0 | 0 |
| NFG and proNGF binds to p75NTR | R-HSA-205017 | 3.149241e-01 | 0.502 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 3.149241e-01 | 0.502 | 0 | 0 |
| Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4), distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA) | R-HSA-5619050 | 3.149241e-01 | 0.502 | 0 | 0 |
| Intestinal infectious diseases | R-HSA-8942233 | 3.149241e-01 | 0.502 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 3.149241e-01 | 0.502 | 0 | 0 |
| Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome | R-HSA-5678420 | 3.149241e-01 | 0.502 | 0 | 0 |
| MyD88 deficiency (TLR5) | R-HSA-5602680 | 3.149241e-01 | 0.502 | 0 | 0 |
| Defective SLC6A2 causes orthostatic intolerance (OI) | R-HSA-5619109 | 3.149241e-01 | 0.502 | 0 | 0 |
| Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 | R-HSA-5083628 | 3.149241e-01 | 0.502 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 3.149241e-01 | 0.502 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 1.338685e-01 | 0.873 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 1.338685e-01 | 0.873 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 2.210911e-01 | 0.655 | 0 | 0 |
| IRS activation | R-HSA-74713 | 2.210911e-01 | 0.655 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 2.210911e-01 | 0.655 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 2.210911e-01 | 0.655 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 2.210911e-01 | 0.655 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 2.210911e-01 | 0.655 | 0 | 0 |
| G2 Phase | R-HSA-68911 | 2.210911e-01 | 0.655 | 0 | 0 |
| RSK activation | R-HSA-444257 | 1.632465e-01 | 0.787 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.236669e-01 | 0.908 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 1.115573e-01 | 0.953 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 1.115573e-01 | 0.953 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 1.943175e-01 | 0.711 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 1.943175e-01 | 0.711 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.943175e-01 | 0.711 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 1.943175e-01 | 0.711 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 2.673717e-01 | 0.573 | 0 | 0 |
| PKA-mediated phosphorylation of key metabolic factors | R-HSA-163358 | 2.673717e-01 | 0.573 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 2.673717e-01 | 0.573 | 0 | 0 |
| SLIT2:ROBO1 increases RHOA activity | R-HSA-8985586 | 2.673717e-01 | 0.573 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 2.673717e-01 | 0.573 | 0 | 0 |
| HHAT G278V doesn't palmitoylate Hh-Np | R-HSA-5658034 | 3.960818e-01 | 0.402 | 0 | 0 |
| Potassium transport channels | R-HSA-1296067 | 3.960818e-01 | 0.402 | 0 | 0 |
| TWIK related potassium channel (TREK) | R-HSA-1299503 | 3.960818e-01 | 0.402 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 3.960818e-01 | 0.402 | 0 | 0 |
| Mitotic Metaphase/Anaphase Transition | R-HSA-68881 | 3.960818e-01 | 0.402 | 0 | 0 |
| Defective SLC6A5 causes hyperekplexia 3 (HKPX3) | R-HSA-5619089 | 3.960818e-01 | 0.402 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 1.292269e-01 | 0.889 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 1.292269e-01 | 0.889 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 1.694864e-01 | 0.771 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 1.694864e-01 | 0.771 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 2.266838e-01 | 0.645 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 1.943269e-01 | 0.711 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in WNT signaling | R-HSA-8939256 | 3.136211e-01 | 0.504 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 3.136211e-01 | 0.504 | 0 | 0 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors | R-HSA-629587 | 3.136211e-01 | 0.504 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 3.136211e-01 | 0.504 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 3.136211e-01 | 0.504 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 2.599688e-01 | 0.585 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 2.599688e-01 | 0.585 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.278010e-01 | 0.893 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.278010e-01 | 0.893 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 2.202011e-01 | 0.657 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 1.889203e-01 | 0.724 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 1.889203e-01 | 0.724 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.423509e-01 | 0.847 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 1.423509e-01 | 0.847 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.423509e-01 | 0.847 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 1.205875e-01 | 0.919 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 1.375936e-01 | 0.861 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.375936e-01 | 0.861 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 2.938238e-01 | 0.532 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 2.938238e-01 | 0.532 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 2.938238e-01 | 0.532 | 0 | 0 |
| PP2A-mediated dephosphorylation of key metabolic factors | R-HSA-163767 | 3.591976e-01 | 0.445 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 3.591976e-01 | 0.445 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 3.591976e-01 | 0.445 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 3.591976e-01 | 0.445 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 3.591976e-01 | 0.445 | 0 | 0 |
| The IPAF inflammasome | R-HSA-844623 | 4.676293e-01 | 0.330 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 4.676293e-01 | 0.330 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of other transcription factors | R-HSA-8866906 | 4.676293e-01 | 0.330 | 0 | 0 |
| IRAK4 deficiency (TLR5) | R-HSA-5603037 | 4.676293e-01 | 0.330 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 4.676293e-01 | 0.330 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 4.676293e-01 | 0.330 | 0 | 0 |
| Defective GCLC causes HAGGSD | R-HSA-5578999 | 4.676293e-01 | 0.330 | 0 | 0 |
| Defective HPRT1 disrupts guanine and hypoxanthine salvage | R-HSA-9734281 | 4.676293e-01 | 0.330 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 4.676293e-01 | 0.330 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 4.676293e-01 | 0.330 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 1.324072e-01 | 0.878 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 1.513046e-01 | 0.820 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.736732e-01 | 0.760 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 1.736732e-01 | 0.760 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.736732e-01 | 0.760 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 2.332401e-01 | 0.632 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 1.448087e-01 | 0.839 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 1.448087e-01 | 0.839 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 1.448087e-01 | 0.839 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 2.742821e-01 | 0.562 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 2.742821e-01 | 0.562 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.903572e-01 | 0.720 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.903572e-01 | 0.720 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 3.279313e-01 | 0.484 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 3.279313e-01 | 0.484 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 3.279313e-01 | 0.484 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 3.279313e-01 | 0.484 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 3.279313e-01 | 0.484 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 3.279313e-01 | 0.484 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 1.064116e-01 | 0.973 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 1.145915e-01 | 0.941 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 2.402254e-01 | 0.619 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 3.021151e-01 | 0.520 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 3.021151e-01 | 0.520 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 4.036121e-01 | 0.394 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 4.036121e-01 | 0.394 | 0 | 0 |
| Activation of RAS in B cells | R-HSA-1169092 | 4.036121e-01 | 0.394 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 4.036121e-01 | 0.394 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 1.541676e-01 | 0.812 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 2.255192e-01 | 0.647 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 3.620075e-01 | 0.441 | 0 | 0 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 3.620075e-01 | 0.441 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 1.340842e-01 | 0.873 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 3.302396e-01 | 0.481 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 1.508669e-01 | 0.821 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.021268e-01 | 0.694 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.820441e-01 | 0.550 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 2.820441e-01 | 0.550 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 1.710592e-01 | 0.767 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 2.819052e-01 | 0.550 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 3.286014e-01 | 0.483 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 3.286014e-01 | 0.483 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 3.584904e-01 | 0.446 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 3.584904e-01 | 0.446 | 0 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 3.584904e-01 | 0.446 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 3.958023e-01 | 0.403 | 0 | 0 |
| CRMPs in Sema3A signaling | R-HSA-399956 | 3.958023e-01 | 0.403 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 3.958023e-01 | 0.403 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 4.465004e-01 | 0.350 | 0 | 0 |
| Interleukin-21 signaling | R-HSA-9020958 | 4.465004e-01 | 0.350 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 4.465004e-01 | 0.350 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 4.465004e-01 | 0.350 | 0 | 0 |
| 5-Phosphoribose 1-diphosphate biosynthesis | R-HSA-73843 | 4.465004e-01 | 0.350 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 5.307041e-01 | 0.275 | 0 | 0 |
| betaKlotho-mediated ligand binding | R-HSA-1307965 | 5.307041e-01 | 0.275 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 5.307041e-01 | 0.275 | 0 | 0 |
| ATP sensitive Potassium channels | R-HSA-1296025 | 5.307041e-01 | 0.275 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 5.307041e-01 | 0.275 | 0 | 0 |
| Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes | R-HSA-69200 | 5.307041e-01 | 0.275 | 0 | 0 |
| GRB7 events in ERBB2 signaling | R-HSA-1306955 | 5.307041e-01 | 0.275 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 5.307041e-01 | 0.275 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 1.719248e-01 | 0.765 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 3.867139e-01 | 0.413 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 3.867139e-01 | 0.413 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 3.867139e-01 | 0.413 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 3.867139e-01 | 0.413 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 3.212331e-01 | 0.493 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 4.290992e-01 | 0.367 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 4.290992e-01 | 0.367 | 0 | 0 |
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 4.290992e-01 | 0.367 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 4.147692e-01 | 0.382 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 4.147692e-01 | 0.382 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 4.147692e-01 | 0.382 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 4.147692e-01 | 0.382 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 4.876009e-01 | 0.312 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 4.876009e-01 | 0.312 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 4.876009e-01 | 0.312 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 3.236339e-01 | 0.490 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 4.024394e-01 | 0.395 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 3.538478e-01 | 0.451 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.915122e-01 | 0.407 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 4.617138e-01 | 0.336 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 3.816319e-01 | 0.418 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 4.425286e-01 | 0.354 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 4.425286e-01 | 0.354 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 4.269436e-01 | 0.370 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 4.269436e-01 | 0.370 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 4.269436e-01 | 0.370 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 4.221639e-01 | 0.375 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 4.221639e-01 | 0.375 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 4.221639e-01 | 0.375 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 4.221639e-01 | 0.375 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 4.512440e-01 | 0.346 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 4.934920e-01 | 0.307 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 5.267354e-01 | 0.278 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 5.267354e-01 | 0.278 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 5.863091e-01 | 0.232 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 5.863091e-01 | 0.232 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 4.169710e-01 | 0.380 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 4.575445e-01 | 0.340 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 4.752612e-01 | 0.323 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 4.752612e-01 | 0.323 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 4.967162e-01 | 0.304 | 0 | 0 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 4.624110e-01 | 0.335 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 5.243076e-01 | 0.280 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 5.243076e-01 | 0.280 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 4.848411e-01 | 0.314 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 5.229556e-01 | 0.282 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 5.229556e-01 | 0.282 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 5.229556e-01 | 0.282 | 0 | 0 |
| Presynaptic nicotinic acetylcholine receptors | R-HSA-622323 | 5.637927e-01 | 0.249 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 5.637927e-01 | 0.249 | 0 | 0 |
| ERKs are inactivated | R-HSA-202670 | 5.637927e-01 | 0.249 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 5.637927e-01 | 0.249 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 5.019921e-01 | 0.299 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 4.888355e-01 | 0.311 | 0 | 0 |
| Developmental Lineage of Multipotent Pancreatic Progenitor Cells | R-HSA-9937080 | 5.221648e-01 | 0.282 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 5.031679e-01 | 0.298 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 5.540605e-01 | 0.256 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 5.214264e-01 | 0.283 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 5.214264e-01 | 0.283 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 5.485210e-01 | 0.261 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 5.405727e-01 | 0.267 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 5.391736e-01 | 0.268 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 5.733492e-01 | 0.242 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 5.987158e-01 | 0.223 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 5.987158e-01 | 0.223 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 5.826118e-01 | 0.235 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 5.888283e-01 | 0.230 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 5.888283e-01 | 0.230 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 5.973884e-01 | 0.224 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 6.100909e-01 | 0.215 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 6.100909e-01 | 0.215 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 6.100909e-01 | 0.215 | 0 | 0 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 6.100909e-01 | 0.215 | 0 | 0 |
| Acetylcholine binding and downstream events | R-HSA-181431 | 6.314901e-01 | 0.200 | 0 | 0 |
| Postsynaptic nicotinic acetylcholine receptors | R-HSA-622327 | 6.314901e-01 | 0.200 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 6.302997e-01 | 0.200 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 2.645089e-01 | 0.578 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 5.217074e-01 | 0.283 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 4.575445e-01 | 0.340 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 2.819052e-01 | 0.550 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 6.130657e-01 | 0.212 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 5.567930e-01 | 0.254 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 1.889203e-01 | 0.724 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 6.097588e-01 | 0.215 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 3.913600e-01 | 0.407 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 3.253045e-01 | 0.488 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 4.752612e-01 | 0.323 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 3.620075e-01 | 0.441 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 3.693690e-01 | 0.433 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 3.728343e-01 | 0.428 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 4.989231e-01 | 0.302 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 5.684019e-01 | 0.245 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 6.097588e-01 | 0.215 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 4.617138e-01 | 0.336 | 0 | 0 |
| Transcriptional regulation of testis differentiation | R-HSA-9690406 | 2.742821e-01 | 0.562 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 4.345835e-01 | 0.362 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 4.530404e-01 | 0.344 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.092644e-01 | 0.962 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 4.465004e-01 | 0.350 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 3.014356e-01 | 0.521 | 0 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 1.508669e-01 | 0.821 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 4.934920e-01 | 0.307 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 5.637927e-01 | 0.249 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 2.454229e-01 | 0.610 | 0 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 1.532188e-01 | 0.815 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 4.290992e-01 | 0.367 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 4.356654e-01 | 0.361 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 4.934920e-01 | 0.307 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 3.365151e-01 | 0.473 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 3.960195e-01 | 0.402 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 6.241268e-01 | 0.205 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 3.066222e-01 | 0.513 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 5.593971e-01 | 0.252 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 5.671644e-01 | 0.246 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 6.314901e-01 | 0.200 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 3.126784e-01 | 0.505 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 2.266838e-01 | 0.645 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.805811e-01 | 0.743 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 4.036121e-01 | 0.394 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 4.876009e-01 | 0.312 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 4.876009e-01 | 0.312 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 4.221639e-01 | 0.375 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 4.477058e-01 | 0.349 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 5.637927e-01 | 0.249 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 5.031679e-01 | 0.298 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 5.449287e-01 | 0.264 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 6.030063e-01 | 0.220 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 2.070494e-01 | 0.684 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 2.742821e-01 | 0.562 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 4.698779e-01 | 0.328 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 2.004954e-01 | 0.698 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 3.695472e-01 | 0.432 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 6.209241e-01 | 0.207 | 0 | 0 |
| Activation of PUMA and translocation to mitochondria | R-HSA-139915 | 1.338685e-01 | 0.873 | 0 | 0 |
| Toxicity of botulinum toxin type E (botE) | R-HSA-5250992 | 2.673717e-01 | 0.573 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 2.266838e-01 | 0.645 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.245398e-01 | 0.905 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 2.469161e-01 | 0.607 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 1.448087e-01 | 0.839 | 0 | 0 |
| Downregulation of ERBB4 signaling | R-HSA-1253288 | 4.036121e-01 | 0.394 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 3.620075e-01 | 0.441 | 0 | 0 |
| Toxicity of botulinum toxin type A (botA) | R-HSA-5250968 | 4.465004e-01 | 0.350 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 4.465004e-01 | 0.350 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 4.290992e-01 | 0.367 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 4.876009e-01 | 0.312 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 4.876009e-01 | 0.312 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 2.982814e-01 | 0.525 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 2.982814e-01 | 0.525 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 4.698779e-01 | 0.328 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 5.006121e-01 | 0.300 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 6.314901e-01 | 0.200 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 5.356043e-01 | 0.271 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 1.680077e-01 | 0.775 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 1.752453e-01 | 0.756 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 1.889203e-01 | 0.724 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 1.884710e-01 | 0.725 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 1.855641e-01 | 0.732 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 3.812267e-01 | 0.419 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 3.126784e-01 | 0.505 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 4.227015e-01 | 0.374 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 5.547073e-01 | 0.256 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 1.917814e-01 | 0.717 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 1.756053e-01 | 0.755 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 1.756053e-01 | 0.755 | 0 | 0 |
| Sodium/Proton exchangers | R-HSA-425986 | 1.632465e-01 | 0.787 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 1.115573e-01 | 0.953 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 3.279313e-01 | 0.484 | 0 | 0 |
| Adrenoceptors | R-HSA-390696 | 4.036121e-01 | 0.394 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 4.036121e-01 | 0.394 | 0 | 0 |
| AMPK inhibits chREBP transcriptional activation activity | R-HSA-163680 | 4.465004e-01 | 0.350 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 5.307041e-01 | 0.275 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 3.014356e-01 | 0.521 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 4.698779e-01 | 0.328 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 5.485210e-01 | 0.261 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 5.485210e-01 | 0.261 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 5.593971e-01 | 0.252 | 0 | 0 |
| Advanced glycosylation endproduct receptor signaling | R-HSA-879415 | 5.987158e-01 | 0.223 | 0 | 0 |
| S Phase | R-HSA-69242 | 2.776303e-01 | 0.557 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 1.653133e-01 | 0.782 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.212611e-01 | 0.283 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 1.680077e-01 | 0.775 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 2.030196e-01 | 0.692 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 5.891782e-01 | 0.230 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 2.200592e-01 | 0.657 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 1.632465e-01 | 0.787 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 2.266838e-01 | 0.645 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 2.332401e-01 | 0.632 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 2.402254e-01 | 0.619 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 2.286027e-01 | 0.641 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 2.820441e-01 | 0.550 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 5.987158e-01 | 0.223 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 5.987158e-01 | 0.223 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 3.816319e-01 | 0.418 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 2.120999e-01 | 0.673 | 0 | 0 |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | R-HSA-8877330 | 3.620075e-01 | 0.441 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 1.128061e-01 | 0.948 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 4.955707e-01 | 0.305 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 4.955707e-01 | 0.305 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 5.212611e-01 | 0.283 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 3.422243e-01 | 0.466 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 1.162862e-01 | 0.934 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 2.076572e-01 | 0.683 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 6.098836e-01 | 0.215 | 1 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 3.035344e-01 | 0.518 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 2.161148e-01 | 0.665 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 4.393301e-01 | 0.357 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 1.875520e-01 | 0.727 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 2.673717e-01 | 0.573 | 0 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 1.292269e-01 | 0.889 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 1.375936e-01 | 0.861 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 2.469161e-01 | 0.607 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 2.469161e-01 | 0.607 | 0 | 0 |
| Ca2+ activated K+ channels | R-HSA-1296052 | 3.591976e-01 | 0.445 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 2.402254e-01 | 0.619 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 3.021151e-01 | 0.520 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 4.036121e-01 | 0.394 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 1.922907e-01 | 0.716 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 1.664910e-01 | 0.779 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 3.693690e-01 | 0.433 | 0 | 0 |
| Arachidonate production from DAG | R-HSA-426048 | 4.876009e-01 | 0.312 | 0 | 0 |
| Formation of the posterior neural plate | R-HSA-9832991 | 5.267354e-01 | 0.278 | 0 | 0 |
| Resolution of AP sites via the single-nucleotide replacement pathway | R-HSA-110381 | 5.863091e-01 | 0.232 | 0 | 0 |
| Activation of AKT2 | R-HSA-165158 | 5.863091e-01 | 0.232 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 5.637927e-01 | 0.249 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 5.485210e-01 | 0.261 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 2.926840e-01 | 0.534 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 1.454313e-01 | 0.837 | 1 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 4.823069e-01 | 0.317 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 4.823069e-01 | 0.317 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 3.167919e-01 | 0.499 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 3.693690e-01 | 0.433 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 3.915122e-01 | 0.407 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 5.424166e-01 | 0.266 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 5.424166e-01 | 0.266 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 2.669300e-01 | 0.574 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 3.270080e-01 | 0.485 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 2.952169e-01 | 0.530 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 2.952169e-01 | 0.530 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 2.012928e-01 | 0.696 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 3.568494e-01 | 0.448 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.943269e-01 | 0.711 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 4.269436e-01 | 0.370 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 3.563186e-01 | 0.448 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 3.563186e-01 | 0.448 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 3.563186e-01 | 0.448 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 3.563186e-01 | 0.448 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 1.270650e-01 | 0.896 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.062924e-01 | 0.973 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 3.645502e-01 | 0.438 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.767391e-01 | 0.753 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 1.756053e-01 | 0.755 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 2.459153e-01 | 0.609 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 4.876009e-01 | 0.312 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 4.425286e-01 | 0.354 | 0 | 0 |
| TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | R-HSA-975110 | 4.934920e-01 | 0.307 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 5.243076e-01 | 0.280 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 5.449287e-01 | 0.264 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 5.685655e-01 | 0.245 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 5.778687e-01 | 0.238 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 3.489305e-01 | 0.457 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 5.540605e-01 | 0.256 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 1.817891e-01 | 0.740 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 5.733492e-01 | 0.242 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 1.699733e-01 | 0.770 | 0 | 0 |
| Kinesins | R-HSA-983189 | 2.443329e-01 | 0.612 | 0 | 0 |
| Receptor Mediated Mitophagy | R-HSA-8934903 | 4.876009e-01 | 0.312 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 4.752612e-01 | 0.323 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 5.637927e-01 | 0.249 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 1.635762e-01 | 0.786 | 1 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 1.805811e-01 | 0.743 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 2.455445e-01 | 0.610 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 1.113544e-01 | 0.953 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 2.255192e-01 | 0.647 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 2.563673e-01 | 0.591 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 1.889203e-01 | 0.724 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 3.591976e-01 | 0.445 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 2.295952e-01 | 0.639 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 4.617138e-01 | 0.336 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 5.243076e-01 | 0.280 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 5.567930e-01 | 0.254 | 0 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 3.728343e-01 | 0.428 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 5.732231e-01 | 0.242 | 1 | 0 |
| Potassium Channels | R-HSA-1296071 | 5.900120e-01 | 0.229 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 3.168970e-01 | 0.499 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.816115e-01 | 0.741 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 2.410030e-01 | 0.618 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 6.130657e-01 | 0.212 | 1 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 3.010739e-01 | 0.521 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 5.229556e-01 | 0.282 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 2.731489e-01 | 0.564 | 0 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 5.732231e-01 | 0.242 | 1 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 1.430109e-01 | 0.845 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 6.271233e-01 | 0.203 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.719248e-01 | 0.765 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 1.902619e-01 | 0.721 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 5.217074e-01 | 0.283 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 2.004954e-01 | 0.698 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 6.209502e-01 | 0.207 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 1.541070e-01 | 0.812 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 2.651084e-01 | 0.577 | 1 | 1 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 3.349672e-01 | 0.475 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 1.130092e-01 | 0.947 | 1 | 0 |
| MTOR signalling | R-HSA-165159 | 2.985513e-01 | 0.525 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 3.732886e-01 | 0.428 | 0 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 4.019080e-01 | 0.396 | 0 | 0 |
| Regulation of MITF-M dependent genes involved in metabolism | R-HSA-9854907 | 1.319626e-01 | 0.880 | 0 | 0 |
| MTF1 activates gene expression | R-HSA-5660489 | 1.756053e-01 | 0.755 | 0 | 0 |
| Regulation of PTEN localization | R-HSA-8948747 | 1.338685e-01 | 0.873 | 0 | 0 |
| RUNX2 regulates chondrocyte maturation | R-HSA-8941284 | 2.210911e-01 | 0.655 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 1.236669e-01 | 0.908 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 1.236669e-01 | 0.908 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 1.943175e-01 | 0.711 | 0 | 0 |
| Acetylcholine inhibits contraction of outer hair cells | R-HSA-9667769 | 2.673717e-01 | 0.573 | 0 | 0 |
| Defective ABCC8 can cause hypo- and hyper-glycemias | R-HSA-5683177 | 3.960818e-01 | 0.402 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 1.694864e-01 | 0.771 | 0 | 0 |
| NF-kB is activated and signals survival | R-HSA-209560 | 2.938238e-01 | 0.532 | 0 | 0 |
| Activated NTRK2 signals through CDK5 | R-HSA-9032845 | 3.591976e-01 | 0.445 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 4.676293e-01 | 0.330 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 2.004954e-01 | 0.698 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 3.279313e-01 | 0.484 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 4.036121e-01 | 0.394 | 0 | 0 |
| Negative regulation of activity of TFAP2 (AP-2) family transcription factors | R-HSA-8866904 | 4.036121e-01 | 0.394 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 3.302396e-01 | 0.481 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 2.820441e-01 | 0.550 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 2.820441e-01 | 0.550 | 0 | 0 |
| Alanine metabolism | R-HSA-8964540 | 5.307041e-01 | 0.275 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 3.212331e-01 | 0.493 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 4.147692e-01 | 0.382 | 0 | 0 |
| Activation of PPARGC1A (PGC-1alpha) by phosphorylation | R-HSA-2151209 | 4.876009e-01 | 0.312 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 3.613897e-01 | 0.442 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 3.538478e-01 | 0.451 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 4.617138e-01 | 0.336 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 4.101745e-01 | 0.387 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 5.267354e-01 | 0.278 | 0 | 0 |
| NTRK2 activates RAC1 | R-HSA-9032759 | 5.863091e-01 | 0.232 | 0 | 0 |
| Suppression of autophagy | R-HSA-9636569 | 5.863091e-01 | 0.232 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 5.243076e-01 | 0.280 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 4.391520e-01 | 0.357 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 5.637927e-01 | 0.249 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 5.637927e-01 | 0.249 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 5.031679e-01 | 0.298 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 5.212426e-01 | 0.283 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 5.424166e-01 | 0.266 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 6.314901e-01 | 0.200 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 2.920389e-01 | 0.535 | 0 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 6.188626e-01 | 0.208 | 1 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 3.458372e-01 | 0.461 | 1 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 2.960813e-01 | 0.529 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 6.302997e-01 | 0.200 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 5.214288e-01 | 0.283 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 2.120548e-01 | 0.674 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 3.778178e-01 | 0.423 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 1.778156e-01 | 0.750 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 2.301415e-01 | 0.638 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 5.877429e-01 | 0.231 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 4.575445e-01 | 0.340 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 6.100909e-01 | 0.215 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 4.758016e-01 | 0.323 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 2.878852e-01 | 0.541 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 2.878852e-01 | 0.541 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 1.905385e-01 | 0.720 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 4.823069e-01 | 0.317 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 5.212426e-01 | 0.283 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 2.784900e-01 | 0.555 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 5.212426e-01 | 0.283 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 4.118197e-01 | 0.385 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 2.110563e-01 | 0.676 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 1.297577e-01 | 0.887 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 3.136211e-01 | 0.504 | 0 | 0 |
| Activated NTRK2 signals through FYN | R-HSA-9032500 | 4.036121e-01 | 0.394 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 2.609140e-01 | 0.584 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 4.136335e-01 | 0.383 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 4.934920e-01 | 0.307 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 2.900466e-01 | 0.538 | 0 | 0 |
| Formation of the nephric duct | R-HSA-9830364 | 3.531720e-01 | 0.452 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 3.302396e-01 | 0.481 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 3.042113e-01 | 0.517 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 2.820441e-01 | 0.550 | 0 | 0 |
| TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 6.314901e-01 | 0.200 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 5.665916e-01 | 0.247 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 2.210911e-01 | 0.655 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 2.210911e-01 | 0.655 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 1.236669e-01 | 0.908 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 1.694864e-01 | 0.771 | 0 | 0 |
| Elevation of cytosolic Ca2+ levels | R-HSA-139853 | 3.021151e-01 | 0.520 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 4.036121e-01 | 0.394 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 2.438870e-01 | 0.613 | 0 | 0 |
| Interleukin-1 processing | R-HSA-448706 | 4.465004e-01 | 0.350 | 0 | 0 |
| Activation of NOXA and translocation to mitochondria | R-HSA-111448 | 5.307041e-01 | 0.275 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 4.698779e-01 | 0.328 | 0 | 0 |
| SARS-CoV-2 modulates autophagy | R-HSA-9754560 | 5.267354e-01 | 0.278 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 2.402254e-01 | 0.619 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.162049e-01 | 0.935 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 1.448087e-01 | 0.839 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 2.245926e-01 | 0.649 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 5.453057e-01 | 0.263 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 1.905385e-01 | 0.720 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 4.465004e-01 | 0.350 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 5.212611e-01 | 0.283 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 6.314901e-01 | 0.200 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 1.245398e-01 | 0.905 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 3.472750e-01 | 0.459 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 3.816319e-01 | 0.418 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.035554e-01 | 0.394 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 4.934920e-01 | 0.307 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 3.728343e-01 | 0.428 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 3.563186e-01 | 0.448 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 2.034594e-01 | 0.692 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 4.698779e-01 | 0.328 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 3.028811e-01 | 0.519 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 2.641799e-01 | 0.578 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 4.227015e-01 | 0.374 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 4.698779e-01 | 0.328 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 2.261506e-01 | 0.646 | 1 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 3.353203e-01 | 0.475 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 3.960818e-01 | 0.402 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 2.266838e-01 | 0.645 | 0 | 0 |
| Synthesis of PI | R-HSA-1483226 | 2.599688e-01 | 0.585 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 2.202011e-01 | 0.657 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 4.676293e-01 | 0.330 | 0 | 0 |
| RAF-independent MAPK1/3 activation | R-HSA-112409 | 2.801114e-01 | 0.553 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 3.620075e-01 | 0.441 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 4.465004e-01 | 0.350 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 4.465004e-01 | 0.350 | 0 | 0 |
| p75NTR negatively regulates cell cycle via SC1 | R-HSA-193670 | 5.307041e-01 | 0.275 | 0 | 0 |
| TNFR1-mediated ceramide production | R-HSA-5626978 | 5.307041e-01 | 0.275 | 0 | 0 |
| Sensory perception of sour taste | R-HSA-9729555 | 5.307041e-01 | 0.275 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.290992e-01 | 0.367 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 4.617138e-01 | 0.336 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 4.617138e-01 | 0.336 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 4.425286e-01 | 0.354 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 5.267354e-01 | 0.278 | 0 | 0 |
| Biosynthesis of DPAn-3-derived 13-series resolvins | R-HSA-9026403 | 5.863091e-01 | 0.232 | 0 | 0 |
| PTK6 Down-Regulation | R-HSA-8849472 | 5.863091e-01 | 0.232 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 4.869826e-01 | 0.312 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 5.449287e-01 | 0.264 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 5.733492e-01 | 0.242 | 0 | 0 |
| rRNA modification in the mitochondrion | R-HSA-6793080 | 6.314901e-01 | 0.200 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 1.527573e-01 | 0.816 | 1 | 0 |
| Ion channel transport | R-HSA-983712 | 2.535800e-01 | 0.596 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 2.191585e-01 | 0.659 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 4.698779e-01 | 0.328 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 5.826737e-01 | 0.235 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 1.311810e-01 | 0.882 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.943175e-01 | 0.711 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 1.694864e-01 | 0.771 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 1.634817e-01 | 0.787 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 4.290992e-01 | 0.367 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 4.848411e-01 | 0.314 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 6.100909e-01 | 0.215 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 6.314901e-01 | 0.200 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 5.826737e-01 | 0.235 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 4.676293e-01 | 0.330 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 2.627022e-01 | 0.581 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 5.267354e-01 | 0.278 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 2.245926e-01 | 0.649 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 5.243076e-01 | 0.280 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 2.210911e-01 | 0.655 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 2.673717e-01 | 0.573 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 3.591976e-01 | 0.445 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 4.036121e-01 | 0.394 | 0 | 0 |
| FLT3 signaling through SRC family kinases | R-HSA-9706374 | 5.307041e-01 | 0.275 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 5.307041e-01 | 0.275 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 3.816319e-01 | 0.418 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 4.019080e-01 | 0.396 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 5.267354e-01 | 0.278 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 5.593971e-01 | 0.252 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression linked to lipogenesis | R-HSA-9029558 | 6.314901e-01 | 0.200 | 0 | 0 |
| Acyl chain remodeling of DAG and TAG | R-HSA-1482883 | 6.314901e-01 | 0.200 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 2.332401e-01 | 0.632 | 0 | 0 |
| TP53 Regulates Transcription of Caspase Activators and Caspases | R-HSA-6803207 | 4.617138e-01 | 0.336 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 2.200592e-01 | 0.657 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 3.399079e-01 | 0.469 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 5.485210e-01 | 0.261 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 5.515893e-01 | 0.258 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.062740e-01 | 0.974 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 5.826737e-01 | 0.235 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.960818e-01 | 0.402 | 0 | 0 |
| Formation of intermediate mesoderm | R-HSA-9761174 | 4.876009e-01 | 0.312 | 0 | 0 |
| Toxicity of botulinum toxin type C (botC) | R-HSA-5250971 | 5.863091e-01 | 0.232 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 4.967162e-01 | 0.304 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 4.060563e-01 | 0.391 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 3.279313e-01 | 0.484 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 5.540605e-01 | 0.256 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 3.613897e-01 | 0.442 | 0 | 0 |
| Interleukin-2 signaling | R-HSA-9020558 | 5.267354e-01 | 0.278 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 5.863091e-01 | 0.232 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 5.987158e-01 | 0.223 | 0 | 0 |
| Butyrophilin (BTN) family interactions | R-HSA-8851680 | 4.465004e-01 | 0.350 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 4.876009e-01 | 0.312 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 5.888283e-01 | 0.230 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 6.353285e-01 | 0.197 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 6.353285e-01 | 0.197 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 6.353285e-01 | 0.197 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 6.353285e-01 | 0.197 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 6.353285e-01 | 0.197 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 6.353285e-01 | 0.197 | 0 | 0 |
| Phase 1 - inactivation of fast Na+ channels | R-HSA-5576894 | 6.353285e-01 | 0.197 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 6.353285e-01 | 0.197 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 6.353285e-01 | 0.197 | 0 | 0 |
| Signaling by RNF43 mutants | R-HSA-5340588 | 6.353285e-01 | 0.197 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 6.353285e-01 | 0.197 | 0 | 0 |
| Terminal pathway of complement | R-HSA-166665 | 6.353285e-01 | 0.197 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 6.353285e-01 | 0.197 | 0 | 0 |
| Ceramide signalling | R-HSA-193681 | 6.353285e-01 | 0.197 | 0 | 0 |
| Phosphorylation of Emi1 | R-HSA-176417 | 6.353285e-01 | 0.197 | 0 | 0 |
| Formation of the Editosome | R-HSA-75094 | 6.353285e-01 | 0.197 | 0 | 0 |
| Release of Hh-Np from the secreting cell | R-HSA-5362798 | 6.353285e-01 | 0.197 | 0 | 0 |
| Signalling to p38 via RIT and RIN | R-HSA-187706 | 6.353285e-01 | 0.197 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 6.353285e-01 | 0.197 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 6.362744e-01 | 0.196 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 6.393077e-01 | 0.194 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 6.393077e-01 | 0.194 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 6.400721e-01 | 0.194 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 6.400721e-01 | 0.194 | 1 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 6.425891e-01 | 0.192 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 6.429451e-01 | 0.192 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 6.429451e-01 | 0.192 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 6.429451e-01 | 0.192 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 6.429451e-01 | 0.192 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 6.458049e-01 | 0.190 | 1 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 6.496261e-01 | 0.187 | 1 | 0 |
| Degradation of DVL | R-HSA-4641258 | 6.500520e-01 | 0.187 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 6.500520e-01 | 0.187 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 6.500520e-01 | 0.187 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 6.500520e-01 | 0.187 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 6.556290e-01 | 0.183 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 6.565363e-01 | 0.183 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 6.571492e-01 | 0.182 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 6.571492e-01 | 0.182 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 6.571492e-01 | 0.182 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 6.612028e-01 | 0.180 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 6.614002e-01 | 0.180 | 1 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 6.621345e-01 | 0.179 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 6.621345e-01 | 0.179 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 6.621345e-01 | 0.179 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 6.621345e-01 | 0.179 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 6.621345e-01 | 0.179 | 0 | 0 |
| Beta oxidation of hexanoyl-CoA to butanoyl-CoA | R-HSA-77350 | 6.621345e-01 | 0.179 | 0 | 0 |
| Beta oxidation of octanoyl-CoA to hexanoyl-CoA | R-HSA-77348 | 6.621345e-01 | 0.179 | 0 | 0 |
| Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA | R-HSA-77310 | 6.621345e-01 | 0.179 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 6.621345e-01 | 0.179 | 0 | 0 |
| TP53 Regulates Transcription of Death Receptors and Ligands | R-HSA-6803211 | 6.621345e-01 | 0.179 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 6.621345e-01 | 0.179 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 6.621345e-01 | 0.179 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 6.630935e-01 | 0.178 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 6.640468e-01 | 0.178 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 6.640788e-01 | 0.178 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 6.644088e-01 | 0.178 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 6.644088e-01 | 0.178 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 6.644088e-01 | 0.178 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 6.691216e-01 | 0.174 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 6.691216e-01 | 0.174 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 6.701708e-01 | 0.174 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 6.729561e-01 | 0.172 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 6.744330e-01 | 0.171 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 6.744330e-01 | 0.171 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 6.744330e-01 | 0.171 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 6.744330e-01 | 0.171 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 6.744330e-01 | 0.171 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 6.785420e-01 | 0.168 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 6.785420e-01 | 0.168 | 0 | 0 |
| STAT5 Activation | R-HSA-9645135 | 6.785420e-01 | 0.168 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 6.785420e-01 | 0.168 | 0 | 0 |
| Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | R-HSA-3656244 | 6.785420e-01 | 0.168 | 0 | 0 |
| Defective CHST6 causes MCDC1 | R-HSA-3656225 | 6.785420e-01 | 0.168 | 0 | 0 |
| Defective CYP11A1 causes AICSR | R-HSA-5579026 | 6.785420e-01 | 0.168 | 0 | 0 |
| Defective ST3GAL3 causes MCT12 and EIEE15 | R-HSA-3656243 | 6.785420e-01 | 0.168 | 0 | 0 |
| Toxicity of botulinum toxin type D (botD) | R-HSA-5250955 | 6.785420e-01 | 0.168 | 0 | 0 |
| Toxicity of botulinum toxin type F (botF) | R-HSA-5250981 | 6.785420e-01 | 0.168 | 0 | 0 |
| Abacavir transmembrane transport | R-HSA-2161517 | 6.785420e-01 | 0.168 | 0 | 0 |
| Activation of NIMA Kinases NEK9, NEK6, NEK7 | R-HSA-2980767 | 6.785420e-01 | 0.168 | 0 | 0 |
| NADPH regeneration | R-HSA-389542 | 6.785420e-01 | 0.168 | 0 | 0 |
| Lipid particle organization | R-HSA-8964572 | 6.785420e-01 | 0.168 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 6.785420e-01 | 0.168 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 6.829414e-01 | 0.166 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 6.848683e-01 | 0.164 | 0 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 6.848683e-01 | 0.164 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 6.848683e-01 | 0.164 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 6.848683e-01 | 0.164 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 6.849744e-01 | 0.164 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 6.849744e-01 | 0.164 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 6.874948e-01 | 0.163 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 6.874948e-01 | 0.163 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 6.898266e-01 | 0.161 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 6.904351e-01 | 0.161 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 6.906935e-01 | 0.161 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 6.906935e-01 | 0.161 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 6.906935e-01 | 0.161 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 6.906935e-01 | 0.161 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 6.906935e-01 | 0.161 | 0 | 0 |
| Lysosphingolipid and LPA receptors | R-HSA-419408 | 6.906935e-01 | 0.161 | 0 | 0 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 6.906935e-01 | 0.161 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 6.906935e-01 | 0.161 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 6.906935e-01 | 0.161 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 6.906935e-01 | 0.161 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 6.906935e-01 | 0.161 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 6.906935e-01 | 0.161 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.919907e-01 | 0.160 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.939477e-01 | 0.159 | 1 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 6.952761e-01 | 0.158 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.952761e-01 | 0.158 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 6.953622e-01 | 0.158 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 6.953900e-01 | 0.158 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 6.957247e-01 | 0.158 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 6.964682e-01 | 0.157 | 0 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 7.010654e-01 | 0.154 | 1 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 7.010654e-01 | 0.154 | 1 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 7.044687e-01 | 0.152 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 7.044687e-01 | 0.152 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 7.046350e-01 | 0.152 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 7.051627e-01 | 0.152 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 7.062580e-01 | 0.151 | 1 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 7.072754e-01 | 0.150 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 7.076302e-01 | 0.150 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 7.076302e-01 | 0.150 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 7.091174e-01 | 0.149 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 7.102718e-01 | 0.149 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 7.127113e-01 | 0.147 | 0 | 0 |
| RUNX1 regulates estrogen receptor mediated transcription | R-HSA-8931987 | 7.166369e-01 | 0.145 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 7.166369e-01 | 0.145 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 7.166369e-01 | 0.145 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 7.166369e-01 | 0.145 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 7.166369e-01 | 0.145 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 7.166369e-01 | 0.145 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 7.166369e-01 | 0.145 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 7.166369e-01 | 0.145 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 7.166369e-01 | 0.145 | 0 | 0 |
| mRNA Editing: C to U Conversion | R-HSA-72200 | 7.166369e-01 | 0.145 | 0 | 0 |
| Electron transport from NADPH to Ferredoxin | R-HSA-2395516 | 7.166369e-01 | 0.145 | 0 | 0 |
| DAG1 core M1 glycosylations | R-HSA-8932506 | 7.166369e-01 | 0.145 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 7.166369e-01 | 0.145 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 7.166369e-01 | 0.145 | 0 | 0 |
| Phase 3 - rapid repolarisation | R-HSA-5576890 | 7.166369e-01 | 0.145 | 0 | 0 |
| Glycoprotein hormones | R-HSA-209822 | 7.166369e-01 | 0.145 | 0 | 0 |
| Nef Mediated CD4 Down-regulation | R-HSA-167590 | 7.166369e-01 | 0.145 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 7.166369e-01 | 0.145 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 7.166369e-01 | 0.145 | 0 | 0 |
| Defective GALNT3 causes HFTC | R-HSA-5083625 | 7.172310e-01 | 0.144 | 0 | 0 |
| Defective GALNT12 causes CRCS1 | R-HSA-5083636 | 7.172310e-01 | 0.144 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 7.172310e-01 | 0.144 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 7.172310e-01 | 0.144 | 0 | 0 |
| Regulation of BACH1 activity | R-HSA-9708530 | 7.172310e-01 | 0.144 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 7.172310e-01 | 0.144 | 0 | 0 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 7.172310e-01 | 0.144 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 7.175123e-01 | 0.144 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 7.183293e-01 | 0.144 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 7.183293e-01 | 0.144 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 7.183293e-01 | 0.144 | 1 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 7.221209e-01 | 0.141 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 7.221209e-01 | 0.141 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 7.221209e-01 | 0.141 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 7.228422e-01 | 0.141 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 7.228422e-01 | 0.141 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 7.233901e-01 | 0.141 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 7.233901e-01 | 0.141 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 7.233901e-01 | 0.141 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 7.272183e-01 | 0.138 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 7.284386e-01 | 0.138 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 7.284386e-01 | 0.138 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 7.289548e-01 | 0.137 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 7.301734e-01 | 0.137 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 7.307140e-01 | 0.136 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 7.308354e-01 | 0.136 | 0 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 7.316229e-01 | 0.136 | 1 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 7.316229e-01 | 0.136 | 1 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 7.328127e-01 | 0.135 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 7.333919e-01 | 0.135 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 7.334399e-01 | 0.135 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 7.383688e-01 | 0.132 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 7.402498e-01 | 0.131 | 0 | 0 |
| Phase 2 - plateau phase | R-HSA-5576893 | 7.418248e-01 | 0.130 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 7.418248e-01 | 0.130 | 0 | 0 |
| Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA | R-HSA-77346 | 7.418248e-01 | 0.130 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 7.418248e-01 | 0.130 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 7.418248e-01 | 0.130 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 7.418248e-01 | 0.130 | 0 | 0 |
| Synthesis of PG | R-HSA-1483148 | 7.418248e-01 | 0.130 | 0 | 0 |
| Response to metal ions | R-HSA-5660526 | 7.418248e-01 | 0.130 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 7.437724e-01 | 0.129 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 7.437724e-01 | 0.129 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 7.483809e-01 | 0.126 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 7.483809e-01 | 0.126 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 7.483809e-01 | 0.126 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 7.502193e-01 | 0.125 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 7.502193e-01 | 0.125 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 7.502193e-01 | 0.125 | 0 | 0 |
| Highly calcium permeable nicotinic acetylcholine receptors | R-HSA-629597 | 7.502193e-01 | 0.125 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 7.502193e-01 | 0.125 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 7.502193e-01 | 0.125 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 7.502193e-01 | 0.125 | 0 | 0 |
| Co-stimulation by ICOS | R-HSA-9927354 | 7.502193e-01 | 0.125 | 0 | 0 |
| Interleukin-9 signaling | R-HSA-8985947 | 7.502193e-01 | 0.125 | 0 | 0 |
| DAG1 core M2 glycosylations | R-HSA-8932504 | 7.502193e-01 | 0.125 | 0 | 0 |
| Nucleotide salvage defects | R-HSA-9734207 | 7.502193e-01 | 0.125 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 7.502193e-01 | 0.125 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 7.507743e-01 | 0.124 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 7.539096e-01 | 0.123 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 7.562812e-01 | 0.121 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 7.569635e-01 | 0.121 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 7.569635e-01 | 0.121 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 7.582105e-01 | 0.120 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 7.582105e-01 | 0.120 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 7.582105e-01 | 0.120 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 7.582105e-01 | 0.120 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 7.582105e-01 | 0.120 | 0 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 7.585372e-01 | 0.120 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 7.606524e-01 | 0.119 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 7.632952e-01 | 0.117 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 7.645630e-01 | 0.117 | 0 | 0 |
| Defective C1GALT1C1 causes TNPS | R-HSA-5083632 | 7.645630e-01 | 0.117 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 7.645630e-01 | 0.117 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 7.650040e-01 | 0.116 | 1 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 7.659806e-01 | 0.116 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 7.659806e-01 | 0.116 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 7.671321e-01 | 0.115 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 7.671321e-01 | 0.115 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 7.671321e-01 | 0.115 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 7.671321e-01 | 0.115 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 7.671321e-01 | 0.115 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 7.671321e-01 | 0.115 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 7.671321e-01 | 0.115 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 7.687498e-01 | 0.114 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 7.691578e-01 | 0.114 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 7.714002e-01 | 0.113 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 7.714002e-01 | 0.113 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 7.743009e-01 | 0.111 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 7.773502e-01 | 0.109 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 7.773502e-01 | 0.109 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 7.773502e-01 | 0.109 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 7.789311e-01 | 0.109 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 7.790335e-01 | 0.108 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 7.791998e-01 | 0.108 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 7.791998e-01 | 0.108 | 0 | 0 |
| Estrogen-stimulated signaling through PRKCZ | R-HSA-9634635 | 7.798234e-01 | 0.108 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 7.798234e-01 | 0.108 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 7.798234e-01 | 0.108 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 7.798234e-01 | 0.108 | 0 | 0 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 7.798234e-01 | 0.108 | 0 | 0 |
| Degradation of GABA | R-HSA-916853 | 7.798234e-01 | 0.108 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 7.798234e-01 | 0.108 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 7.798234e-01 | 0.108 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 7.798234e-01 | 0.108 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 7.798234e-01 | 0.108 | 0 | 0 |
| Lysosomal oligosaccharide catabolism | R-HSA-8853383 | 7.798234e-01 | 0.108 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 7.805964e-01 | 0.108 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 7.824213e-01 | 0.107 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 7.824213e-01 | 0.107 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 7.828986e-01 | 0.106 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 7.847278e-01 | 0.105 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 7.847278e-01 | 0.105 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 7.847278e-01 | 0.105 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | R-HSA-6803204 | 7.847278e-01 | 0.105 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 7.855399e-01 | 0.105 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 7.855399e-01 | 0.105 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 7.855399e-01 | 0.105 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 7.855399e-01 | 0.105 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 7.855399e-01 | 0.105 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 7.855399e-01 | 0.105 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 7.865256e-01 | 0.104 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 7.865256e-01 | 0.104 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 7.876806e-01 | 0.104 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 7.888066e-01 | 0.103 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 7.895348e-01 | 0.103 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 7.895348e-01 | 0.103 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 7.918475e-01 | 0.101 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 7.957231e-01 | 0.099 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 7.958196e-01 | 0.099 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 7.963678e-01 | 0.099 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 7.963678e-01 | 0.099 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 7.963678e-01 | 0.099 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 7.988829e-01 | 0.098 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 8.001336e-01 | 0.097 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 8.012077e-01 | 0.096 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 8.012077e-01 | 0.096 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 8.039336e-01 | 0.095 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 8.039336e-01 | 0.095 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 8.039336e-01 | 0.095 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 8.048534e-01 | 0.094 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 8.048534e-01 | 0.094 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 8.048534e-01 | 0.094 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 8.059204e-01 | 0.094 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 8.059204e-01 | 0.094 | 0 | 0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | R-HSA-629594 | 8.059204e-01 | 0.094 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 8.059204e-01 | 0.094 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 8.059204e-01 | 0.094 | 0 | 0 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 8.059204e-01 | 0.094 | 0 | 0 |
| Pexophagy | R-HSA-9664873 | 8.059204e-01 | 0.094 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 8.059204e-01 | 0.094 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 8.059204e-01 | 0.094 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 8.059204e-01 | 0.094 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 8.059204e-01 | 0.094 | 0 | 0 |
| Peptide hormone biosynthesis | R-HSA-209952 | 8.059204e-01 | 0.094 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 8.082014e-01 | 0.092 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 8.091712e-01 | 0.092 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 8.093224e-01 | 0.092 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 8.140572e-01 | 0.089 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 8.154646e-01 | 0.089 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 8.154646e-01 | 0.089 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 8.154646e-01 | 0.089 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 8.161836e-01 | 0.088 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 8.166150e-01 | 0.088 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 8.166150e-01 | 0.088 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 8.166169e-01 | 0.088 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 8.175216e-01 | 0.088 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 8.187770e-01 | 0.087 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 8.193442e-01 | 0.087 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 8.213248e-01 | 0.085 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 8.222703e-01 | 0.085 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 8.226030e-01 | 0.085 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 8.226030e-01 | 0.085 | 0 | 0 |
| Pregnenolone biosynthesis | R-HSA-196108 | 8.226030e-01 | 0.085 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 8.226030e-01 | 0.085 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 8.226030e-01 | 0.085 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 8.267744e-01 | 0.083 | 0 | 0 |
| Presynaptic depolarization and calcium channel opening | R-HSA-112308 | 8.289255e-01 | 0.081 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 8.289255e-01 | 0.081 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 8.289255e-01 | 0.081 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 8.289255e-01 | 0.081 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 8.289255e-01 | 0.081 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 8.289255e-01 | 0.081 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 8.289255e-01 | 0.081 | 0 | 0 |
| Biosynthesis of DPAn-3-derived maresins | R-HSA-9026290 | 8.289255e-01 | 0.081 | 0 | 0 |
| Inorganic anion exchange by SLC26 transporters | R-HSA-427601 | 8.289255e-01 | 0.081 | 0 | 0 |
| Suppression of apoptosis | R-HSA-9635465 | 8.289255e-01 | 0.081 | 0 | 0 |
| Prostanoid ligand receptors | R-HSA-391908 | 8.289255e-01 | 0.081 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 8.289255e-01 | 0.081 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 8.289255e-01 | 0.081 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 8.303249e-01 | 0.081 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 8.303249e-01 | 0.081 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 8.309952e-01 | 0.080 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 8.309952e-01 | 0.080 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 8.309952e-01 | 0.080 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 8.329997e-01 | 0.079 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 8.330588e-01 | 0.079 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 8.340122e-01 | 0.079 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 8.369183e-01 | 0.077 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 8.388882e-01 | 0.076 | 1 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 8.388882e-01 | 0.076 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 8.388882e-01 | 0.076 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 8.388882e-01 | 0.076 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 8.397711e-01 | 0.076 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 8.397711e-01 | 0.076 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 8.397711e-01 | 0.076 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.404864e-01 | 0.075 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 8.423711e-01 | 0.074 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 8.437531e-01 | 0.074 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 8.438977e-01 | 0.074 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.443953e-01 | 0.073 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 8.443953e-01 | 0.073 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 8.443953e-01 | 0.073 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 8.468663e-01 | 0.072 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 8.468663e-01 | 0.072 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 8.492049e-01 | 0.071 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 8.492049e-01 | 0.071 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by WNT ligand antagonists | R-HSA-3772470 | 8.492049e-01 | 0.071 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 8.492049e-01 | 0.071 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 8.492049e-01 | 0.071 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 8.492049e-01 | 0.071 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 8.492049e-01 | 0.071 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 8.536893e-01 | 0.069 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 8.536893e-01 | 0.069 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 8.538066e-01 | 0.069 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 8.538066e-01 | 0.069 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 8.538066e-01 | 0.069 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 8.538066e-01 | 0.069 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 8.538066e-01 | 0.069 | 1 | 1 |
| Assembly Of The HIV Virion | R-HSA-175474 | 8.538066e-01 | 0.069 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 8.540661e-01 | 0.069 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 8.563142e-01 | 0.067 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 8.568633e-01 | 0.067 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 8.576810e-01 | 0.067 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 8.624242e-01 | 0.064 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 8.634489e-01 | 0.064 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 8.638055e-01 | 0.064 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 8.638055e-01 | 0.064 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 8.643092e-01 | 0.063 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 8.643092e-01 | 0.063 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 8.649482e-01 | 0.063 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 8.652771e-01 | 0.063 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 8.656696e-01 | 0.063 | 0 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.670814e-01 | 0.062 | 0 | 0 |
| Beta oxidation of palmitoyl-CoA to myristoyl-CoA | R-HSA-77305 | 8.670814e-01 | 0.062 | 0 | 0 |
| Beta oxidation of myristoyl-CoA to lauroyl-CoA | R-HSA-77285 | 8.670814e-01 | 0.062 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 8.670814e-01 | 0.062 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 8.670814e-01 | 0.062 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.670814e-01 | 0.062 | 0 | 0 |
| Regulation of IFNG signaling | R-HSA-877312 | 8.670814e-01 | 0.062 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 8.670814e-01 | 0.062 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 8.670814e-01 | 0.062 | 0 | 0 |
| Biosynthesis of DPAn-3-derived protectins and resolvins | R-HSA-9026286 | 8.670814e-01 | 0.062 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 8.670814e-01 | 0.062 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 8.670814e-01 | 0.062 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.670814e-01 | 0.062 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 8.670814e-01 | 0.062 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 8.670814e-01 | 0.062 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 8.670814e-01 | 0.062 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 8.670814e-01 | 0.062 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 8.670814e-01 | 0.062 | 0 | 0 |
| Erythrocytes take up oxygen and release carbon dioxide | R-HSA-1247673 | 8.670814e-01 | 0.062 | 0 | 0 |
| Estrogen biosynthesis | R-HSA-193144 | 8.670814e-01 | 0.062 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.670814e-01 | 0.062 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 8.674533e-01 | 0.062 | 0 | 0 |
| Neurotoxicity of clostridium toxins | R-HSA-168799 | 8.674533e-01 | 0.062 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 8.674533e-01 | 0.062 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 8.674533e-01 | 0.062 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 8.674533e-01 | 0.062 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 8.674533e-01 | 0.062 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 8.674533e-01 | 0.062 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 8.676100e-01 | 0.062 | 0 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 8.678763e-01 | 0.062 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 8.684474e-01 | 0.061 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.729923e-01 | 0.059 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 8.757517e-01 | 0.058 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 8.763651e-01 | 0.057 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 8.785897e-01 | 0.056 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 8.791154e-01 | 0.056 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 8.791957e-01 | 0.056 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 8.791957e-01 | 0.056 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 8.791957e-01 | 0.056 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 8.799201e-01 | 0.056 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 8.799201e-01 | 0.056 | 0 | 0 |
| Termination of O-glycan biosynthesis | R-HSA-977068 | 8.799201e-01 | 0.056 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 8.799201e-01 | 0.056 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 8.799201e-01 | 0.056 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 8.816599e-01 | 0.055 | 1 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 8.818119e-01 | 0.055 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 8.819790e-01 | 0.055 | 0 | 0 |
| FGFR4 ligand binding and activation | R-HSA-190322 | 8.828396e-01 | 0.054 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 8.828396e-01 | 0.054 | 0 | 0 |
| IL-6-type cytokine receptor ligand interactions | R-HSA-6788467 | 8.828396e-01 | 0.054 | 0 | 0 |
| Chylomicron remodeling | R-HSA-8963901 | 8.828396e-01 | 0.054 | 0 | 0 |
| Diseases of nucleotide metabolism | R-HSA-9735804 | 8.828396e-01 | 0.054 | 0 | 0 |
| Replication of the SARS-CoV-1 genome | R-HSA-9682706 | 8.828396e-01 | 0.054 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 8.835757e-01 | 0.054 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 8.891557e-01 | 0.051 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 8.891557e-01 | 0.051 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 8.891557e-01 | 0.051 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 8.891557e-01 | 0.051 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 8.891557e-01 | 0.051 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 8.912950e-01 | 0.050 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 8.912950e-01 | 0.050 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 8.922832e-01 | 0.049 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 8.942368e-01 | 0.049 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 8.943356e-01 | 0.048 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.943356e-01 | 0.048 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 8.967303e-01 | 0.047 | 0 | 0 |
| Biosynthesis of E-series 18(R)-resolvins | R-HSA-9023661 | 8.967303e-01 | 0.047 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.967303e-01 | 0.047 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.967303e-01 | 0.047 | 0 | 0 |
| Glycerophospholipid catabolism | R-HSA-6814848 | 8.967303e-01 | 0.047 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.967303e-01 | 0.047 | 0 | 0 |
| HDL assembly | R-HSA-8963896 | 8.967303e-01 | 0.047 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 8.967303e-01 | 0.047 | 0 | 0 |
| SARS-CoV-1 Genome Replication and Transcription | R-HSA-9679514 | 8.967303e-01 | 0.047 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 8.970168e-01 | 0.047 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 8.970696e-01 | 0.047 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 8.974532e-01 | 0.047 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 8.974532e-01 | 0.047 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 8.974532e-01 | 0.047 | 0 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 8.983738e-01 | 0.047 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 8.983738e-01 | 0.047 | 0 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 8.983738e-01 | 0.047 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 8.983738e-01 | 0.047 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 8.983738e-01 | 0.047 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.002672e-01 | 0.046 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 9.004141e-01 | 0.046 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 9.004141e-01 | 0.046 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 9.004141e-01 | 0.046 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 9.004141e-01 | 0.046 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 9.004141e-01 | 0.046 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 9.004141e-01 | 0.046 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.016615e-01 | 0.045 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.016615e-01 | 0.045 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 9.016615e-01 | 0.045 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.016615e-01 | 0.045 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 9.016615e-01 | 0.045 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.033818e-01 | 0.044 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 9.061050e-01 | 0.043 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 9.068953e-01 | 0.042 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 9.079982e-01 | 0.042 | 0 | 0 |
| Immune System | R-HSA-168256 | 9.081654e-01 | 0.042 | 1 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 9.089749e-01 | 0.041 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 9.089749e-01 | 0.041 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 9.089749e-01 | 0.041 | 0 | 0 |
| Phospholipase C-mediated cascade; FGFR4 | R-HSA-5654228 | 9.089749e-01 | 0.041 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 9.089749e-01 | 0.041 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 9.089749e-01 | 0.041 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 9.089749e-01 | 0.041 | 1 | 1 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 9.089749e-01 | 0.041 | 0 | 0 |
| Protein lipoylation | R-HSA-9857492 | 9.089749e-01 | 0.041 | 0 | 0 |
| Beta oxidation of butanoyl-CoA to acetyl-CoA | R-HSA-77352 | 9.089749e-01 | 0.041 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 9.089749e-01 | 0.041 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 9.089749e-01 | 0.041 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 9.094898e-01 | 0.041 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 9.097764e-01 | 0.041 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 9.110988e-01 | 0.040 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.110988e-01 | 0.040 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 9.147640e-01 | 0.039 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 9.150648e-01 | 0.039 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.150648e-01 | 0.039 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 9.177208e-01 | 0.037 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 9.190692e-01 | 0.037 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 9.196814e-01 | 0.036 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 9.197683e-01 | 0.036 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 9.197683e-01 | 0.036 | 0 | 0 |
| Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion | R-HSA-434316 | 9.197683e-01 | 0.036 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 9.197683e-01 | 0.036 | 0 | 0 |
| Fructose catabolism | R-HSA-70350 | 9.197683e-01 | 0.036 | 0 | 0 |
| Differentiation of naive CD+ T cells to T helper 1 cells (Th1 cells) | R-HSA-9942503 | 9.197683e-01 | 0.036 | 0 | 0 |
| Differentiation of T cells | R-HSA-9945266 | 9.197683e-01 | 0.036 | 0 | 0 |
| Synthesis of wybutosine at G37 of tRNA(Phe) | R-HSA-6782861 | 9.197683e-01 | 0.036 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 9.197683e-01 | 0.036 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 9.197683e-01 | 0.036 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 9.206241e-01 | 0.036 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 9.210600e-01 | 0.036 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 9.226208e-01 | 0.035 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 9.236446e-01 | 0.034 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 9.236446e-01 | 0.034 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.236446e-01 | 0.034 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 9.238265e-01 | 0.034 | 0 | 0 |
| Telomere Extension By Telomerase | R-HSA-171319 | 9.274793e-01 | 0.033 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.274793e-01 | 0.033 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 9.274793e-01 | 0.033 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.274793e-01 | 0.033 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.274793e-01 | 0.033 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.287107e-01 | 0.032 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 9.287107e-01 | 0.032 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.289884e-01 | 0.032 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.289884e-01 | 0.032 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.289884e-01 | 0.032 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.291870e-01 | 0.032 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.291870e-01 | 0.032 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 9.292824e-01 | 0.032 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 9.292824e-01 | 0.032 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of unsaturated fatty acids | R-HSA-77288 | 9.292824e-01 | 0.032 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 9.292824e-01 | 0.032 | 0 | 0 |
| tRNA modification in the mitochondrion | R-HSA-6787450 | 9.292824e-01 | 0.032 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 9.296935e-01 | 0.032 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.300758e-01 | 0.031 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 9.300758e-01 | 0.031 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 9.318173e-01 | 0.031 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 9.344233e-01 | 0.029 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 9.345579e-01 | 0.029 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 9.345579e-01 | 0.029 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 9.345579e-01 | 0.029 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 9.348678e-01 | 0.029 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 9.348811e-01 | 0.029 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.355744e-01 | 0.029 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 9.376435e-01 | 0.028 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 9.376688e-01 | 0.028 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 9.376688e-01 | 0.028 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 9.376688e-01 | 0.028 | 0 | 0 |
| Biosynthesis of aspirin-triggered D-series resolvins | R-HSA-9020265 | 9.376688e-01 | 0.028 | 0 | 0 |
| Catecholamine biosynthesis | R-HSA-209905 | 9.376688e-01 | 0.028 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 9.376688e-01 | 0.028 | 0 | 0 |
| GDP-fucose biosynthesis | R-HSA-6787639 | 9.376688e-01 | 0.028 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 9.376688e-01 | 0.028 | 0 | 0 |
| Replication of the SARS-CoV-2 genome | R-HSA-9694686 | 9.376688e-01 | 0.028 | 0 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.392065e-01 | 0.027 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.393156e-01 | 0.027 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 9.405307e-01 | 0.027 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 9.405307e-01 | 0.027 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.406944e-01 | 0.027 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 9.420940e-01 | 0.026 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 9.436072e-01 | 0.025 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.436799e-01 | 0.025 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 9.436799e-01 | 0.025 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 9.450610e-01 | 0.025 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 9.450610e-01 | 0.025 | 0 | 0 |
| Biosynthesis of Lipoxins (LX) | R-HSA-2142700 | 9.450610e-01 | 0.025 | 0 | 0 |
| Cytosolic iron-sulfur cluster assembly | R-HSA-2564830 | 9.450610e-01 | 0.025 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 9.450610e-01 | 0.025 | 0 | 0 |
| Vitamin D (calciferol) metabolism | R-HSA-196791 | 9.450610e-01 | 0.025 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 9.450610e-01 | 0.025 | 0 | 0 |
| Organic anion transport by SLC5/17/25 transporters | R-HSA-428643 | 9.450610e-01 | 0.025 | 0 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.457344e-01 | 0.024 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 9.457344e-01 | 0.024 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 9.457344e-01 | 0.024 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.457344e-01 | 0.024 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 9.459361e-01 | 0.024 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 9.467964e-01 | 0.024 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.468547e-01 | 0.024 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 9.481391e-01 | 0.023 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 9.505119e-01 | 0.022 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 9.505119e-01 | 0.022 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.506769e-01 | 0.022 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 9.510635e-01 | 0.022 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.515770e-01 | 0.022 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 9.515770e-01 | 0.022 | 0 | 0 |
| O2/CO2 exchange in erythrocytes | R-HSA-1480926 | 9.515770e-01 | 0.022 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 9.515770e-01 | 0.022 | 0 | 0 |
| Erythrocytes take up carbon dioxide and release oxygen | R-HSA-1237044 | 9.515770e-01 | 0.022 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 9.515770e-01 | 0.022 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 9.515770e-01 | 0.022 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 9.515770e-01 | 0.022 | 0 | 0 |
| SARS-CoV-2 Genome Replication and Transcription | R-HSA-9694682 | 9.515770e-01 | 0.022 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 9.518548e-01 | 0.021 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 9.520652e-01 | 0.021 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 9.520652e-01 | 0.021 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 9.521225e-01 | 0.021 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 9.523348e-01 | 0.021 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 9.527909e-01 | 0.021 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 9.535528e-01 | 0.021 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 9.548946e-01 | 0.020 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 9.558596e-01 | 0.020 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 9.562159e-01 | 0.019 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 9.568331e-01 | 0.019 | 0 | 0 |
| Defective B3GALTL causes PpS | R-HSA-5083635 | 9.568331e-01 | 0.019 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 9.568331e-01 | 0.019 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.568331e-01 | 0.019 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 9.568331e-01 | 0.019 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 9.573205e-01 | 0.019 | 0 | 0 |
| Keratan sulfate degradation | R-HSA-2022857 | 9.573205e-01 | 0.019 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 9.573205e-01 | 0.019 | 0 | 0 |
| Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.573205e-01 | 0.019 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.573205e-01 | 0.019 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.598035e-01 | 0.018 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.611447e-01 | 0.017 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.611447e-01 | 0.017 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 9.623830e-01 | 0.017 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 9.623830e-01 | 0.017 | 0 | 0 |
| Biosynthesis of E-series 18(S)-resolvins | R-HSA-9018896 | 9.623830e-01 | 0.017 | 0 | 0 |
| Phenylalanine metabolism | R-HSA-8964208 | 9.623830e-01 | 0.017 | 0 | 0 |
| PD-L1(CD274) glycosylation and translocation to plasma membrane | R-HSA-9931295 | 9.623830e-01 | 0.017 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.623830e-01 | 0.017 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 9.630859e-01 | 0.016 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 9.648794e-01 | 0.016 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 9.650412e-01 | 0.015 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 9.650412e-01 | 0.015 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.650412e-01 | 0.015 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 9.650412e-01 | 0.015 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 9.654383e-01 | 0.015 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.656773e-01 | 0.015 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 9.659592e-01 | 0.015 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 9.659592e-01 | 0.015 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.666504e-01 | 0.015 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 9.668453e-01 | 0.015 | 0 | 0 |
| Molybdenum cofactor biosynthesis | R-HSA-947581 | 9.668453e-01 | 0.015 | 0 | 0 |
| Glutathione synthesis and recycling | R-HSA-174403 | 9.668453e-01 | 0.015 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.681623e-01 | 0.014 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.685603e-01 | 0.014 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 9.686793e-01 | 0.014 | 0 | 0 |
| Diseases associated with O-glycosylation of proteins | R-HSA-3906995 | 9.702455e-01 | 0.013 | 0 | 0 |
| Biosynthesis of D-series resolvins | R-HSA-9018676 | 9.707785e-01 | 0.013 | 0 | 0 |
| Fructose metabolism | R-HSA-5652084 | 9.707785e-01 | 0.013 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.707785e-01 | 0.013 | 0 | 0 |
| Glycosphingolipid transport | R-HSA-9845576 | 9.717367e-01 | 0.012 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 9.717367e-01 | 0.012 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 9.720814e-01 | 0.012 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 9.722396e-01 | 0.012 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 9.742453e-01 | 0.011 | 0 | 0 |
| Free fatty acids regulate insulin secretion | R-HSA-400451 | 9.742453e-01 | 0.011 | 0 | 0 |
| Interleukin-20 family signaling | R-HSA-8854691 | 9.742453e-01 | 0.011 | 0 | 0 |
| Synthesis of pyrophosphates in the cytosol | R-HSA-1855167 | 9.742453e-01 | 0.011 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.742453e-01 | 0.011 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 9.742453e-01 | 0.011 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 9.744260e-01 | 0.011 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 9.745753e-01 | 0.011 | 0 | 0 |
| O-glycosylation of TSR domain-containing proteins | R-HSA-5173214 | 9.746021e-01 | 0.011 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 9.746021e-01 | 0.011 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 9.746438e-01 | 0.011 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.760671e-01 | 0.011 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 9.765061e-01 | 0.010 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 9.771736e-01 | 0.010 | 0 | 0 |
| Depurination | R-HSA-73927 | 9.771857e-01 | 0.010 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 9.771857e-01 | 0.010 | 0 | 0 |
| Translocation of ZAP-70 to Immunological synapse | R-HSA-202430 | 9.773009e-01 | 0.010 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 9.773009e-01 | 0.010 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.773009e-01 | 0.010 | 0 | 0 |
| Assembly of active LPL and LIPC lipase complexes | R-HSA-8963889 | 9.773009e-01 | 0.010 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 9.773009e-01 | 0.010 | 0 | 0 |
| Synthesis of dolichyl-phosphate | R-HSA-446199 | 9.773009e-01 | 0.010 | 0 | 0 |
| TNFs bind their physiological receptors | R-HSA-5669034 | 9.773009e-01 | 0.010 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.773009e-01 | 0.010 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 9.780220e-01 | 0.010 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 9.786256e-01 | 0.009 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 9.789144e-01 | 0.009 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 9.789144e-01 | 0.009 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 9.789144e-01 | 0.009 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.795140e-01 | 0.009 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.799942e-01 | 0.009 | 0 | 0 |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | R-HSA-9027604 | 9.799942e-01 | 0.009 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.799942e-01 | 0.009 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 9.799942e-01 | 0.009 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 9.808666e-01 | 0.008 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 9.813040e-01 | 0.008 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 9.815675e-01 | 0.008 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 9.816111e-01 | 0.008 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.816111e-01 | 0.008 | 0 | 0 |
| rRNA processing in the mitochondrion | R-HSA-8868766 | 9.816111e-01 | 0.008 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 9.823194e-01 | 0.008 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 9.823681e-01 | 0.008 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.823681e-01 | 0.008 | 0 | 0 |
| Abacavir ADME | R-HSA-2161522 | 9.823681e-01 | 0.008 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 9.823681e-01 | 0.008 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.825683e-01 | 0.008 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 9.826454e-01 | 0.008 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 9.826525e-01 | 0.008 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 9.834014e-01 | 0.007 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 9.834992e-01 | 0.007 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 9.834992e-01 | 0.007 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 9.834992e-01 | 0.007 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.842653e-01 | 0.007 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 9.844604e-01 | 0.007 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 9.844604e-01 | 0.007 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.844604e-01 | 0.007 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.844604e-01 | 0.007 | 0 | 0 |
| Biosynthesis of DPAn-3 SPMs | R-HSA-9025094 | 9.844604e-01 | 0.007 | 0 | 0 |
| Triglyceride biosynthesis | R-HSA-75109 | 9.844604e-01 | 0.007 | 0 | 0 |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | R-HSA-193807 | 9.844604e-01 | 0.007 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.844604e-01 | 0.007 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 9.844604e-01 | 0.007 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 9.844604e-01 | 0.007 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 9.860066e-01 | 0.006 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.863045e-01 | 0.006 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 9.865155e-01 | 0.006 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 9.866076e-01 | 0.006 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 9.867265e-01 | 0.006 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.867265e-01 | 0.006 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 9.867265e-01 | 0.006 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.870811e-01 | 0.006 | 0 | 0 |
| Thyroxine biosynthesis | R-HSA-209968 | 9.879299e-01 | 0.005 | 0 | 0 |
| Biosynthesis of EPA-derived SPMs | R-HSA-9018679 | 9.879299e-01 | 0.005 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 9.879786e-01 | 0.005 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.881006e-01 | 0.005 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 9.893357e-01 | 0.005 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.893357e-01 | 0.005 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 9.893625e-01 | 0.005 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.893625e-01 | 0.005 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.894091e-01 | 0.005 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 9.894819e-01 | 0.005 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.894819e-01 | 0.005 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 9.895149e-01 | 0.005 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.904159e-01 | 0.004 | 0 | 0 |
| mitochondrial fatty acid beta-oxidation of saturated fatty acids | R-HSA-77286 | 9.904453e-01 | 0.004 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 9.906251e-01 | 0.004 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 9.906251e-01 | 0.004 | 0 | 0 |
| Biosynthesis of DPA-derived SPMs | R-HSA-9018683 | 9.906251e-01 | 0.004 | 0 | 0 |
| Synthesis of glycosylphosphatidylinositol (GPI) | R-HSA-162710 | 9.906251e-01 | 0.004 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 9.913301e-01 | 0.004 | 0 | 0 |
| Signaling by Retinoic Acid | R-HSA-5362517 | 9.913301e-01 | 0.004 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.913301e-01 | 0.004 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.916516e-01 | 0.004 | 0 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.917379e-01 | 0.004 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 9.919112e-01 | 0.004 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.921598e-01 | 0.003 | 0 | 0 |
| Synthesis of PC | R-HSA-1483191 | 9.923364e-01 | 0.003 | 0 | 0 |
| Keratan sulfate biosynthesis | R-HSA-2022854 | 9.927186e-01 | 0.003 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.927594e-01 | 0.003 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 9.929774e-01 | 0.003 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 9.931393e-01 | 0.003 | 0 | 0 |
| Glutamate and glutamine metabolism | R-HSA-8964539 | 9.935830e-01 | 0.003 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 9.935830e-01 | 0.003 | 0 | 0 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 9.938596e-01 | 0.003 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.940054e-01 | 0.003 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.940727e-01 | 0.003 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.941464e-01 | 0.003 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 9.942903e-01 | 0.002 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 9.943449e-01 | 0.002 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 9.943449e-01 | 0.002 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 9.943449e-01 | 0.002 | 0 | 0 |
| RA biosynthesis pathway | R-HSA-5365859 | 9.943449e-01 | 0.002 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.943449e-01 | 0.002 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.945057e-01 | 0.002 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.945483e-01 | 0.002 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.945483e-01 | 0.002 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 9.947768e-01 | 0.002 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.950163e-01 | 0.002 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 9.950163e-01 | 0.002 | 0 | 0 |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | R-HSA-193775 | 9.950163e-01 | 0.002 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.950437e-01 | 0.002 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 9.955574e-01 | 0.002 | 0 | 0 |
| Metabolism of steroid hormones | R-HSA-196071 | 9.957413e-01 | 0.002 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.957413e-01 | 0.002 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.958768e-01 | 0.002 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 9.959075e-01 | 0.002 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.959800e-01 | 0.002 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 9.961295e-01 | 0.002 | 0 | 0 |
| SLC-mediated transport of organic cations | R-HSA-549127 | 9.961295e-01 | 0.002 | 0 | 0 |
| Phenylalanine and tyrosine metabolism | R-HSA-8963691 | 9.961295e-01 | 0.002 | 0 | 0 |
| Beta-oxidation of very long chain fatty acids | R-HSA-390247 | 9.961295e-01 | 0.002 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.961295e-01 | 0.002 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.961295e-01 | 0.002 | 0 | 0 |
| O-linked glycosylation of mucins | R-HSA-913709 | 9.961573e-01 | 0.002 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.964188e-01 | 0.002 | 1 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 9.964324e-01 | 0.002 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 9.965146e-01 | 0.002 | 0 | 0 |
| Purine salvage | R-HSA-74217 | 9.965892e-01 | 0.001 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 9.967042e-01 | 0.001 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.968594e-01 | 0.001 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 9.968739e-01 | 0.001 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.968739e-01 | 0.001 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.969942e-01 | 0.001 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 9.969942e-01 | 0.001 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 9.970257e-01 | 0.001 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 9.973309e-01 | 0.001 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 9.973512e-01 | 0.001 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 9.973512e-01 | 0.001 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 9.973512e-01 | 0.001 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.974927e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.974927e-01 | 0.001 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.977128e-01 | 0.001 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 9.977128e-01 | 0.001 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 9.977604e-01 | 0.001 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.978541e-01 | 0.001 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.978541e-01 | 0.001 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 9.979263e-01 | 0.001 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.979378e-01 | 0.001 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.979430e-01 | 0.001 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 9.981811e-01 | 0.001 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 9.981874e-01 | 0.001 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.981874e-01 | 0.001 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.982140e-01 | 0.001 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.983780e-01 | 0.001 | 0 | 0 |
| Pyrimidine catabolism | R-HSA-73621 | 9.984027e-01 | 0.001 | 0 | 0 |
| Endogenous sterols | R-HSA-211976 | 9.984056e-01 | 0.001 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 9.984406e-01 | 0.001 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 9.985925e-01 | 0.001 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.985925e-01 | 0.001 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 9.986025e-01 | 0.001 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 9.986134e-01 | 0.001 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 9.986867e-01 | 0.001 | 0 | 0 |
| Diseases associated with glycosaminoglycan metabolism | R-HSA-3560782 | 9.987597e-01 | 0.001 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.987597e-01 | 0.001 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.988545e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.988545e-01 | 0.000 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 9.990369e-01 | 0.000 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 9.990655e-01 | 0.000 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.991513e-01 | 0.000 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 9.991906e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | R-HSA-193368 | 9.991957e-01 | 0.000 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 9.992056e-01 | 0.000 | 0 | 0 |
| Keratan sulfate/keratin metabolism | R-HSA-1638074 | 9.992522e-01 | 0.000 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.992522e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.992833e-01 | 0.000 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 9.993027e-01 | 0.000 | 0 | 0 |
| Complex IV assembly | R-HSA-9864848 | 9.994194e-01 | 0.000 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 9.994300e-01 | 0.000 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 9.994333e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.994333e-01 | 0.000 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.994410e-01 | 0.000 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 9.994884e-01 | 0.000 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.994919e-01 | 0.000 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 9.995346e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.995472e-01 | 0.000 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.996028e-01 | 0.000 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 9.996798e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.996849e-01 | 0.000 | 0 | 0 |
| Digestion | R-HSA-8935690 | 9.996916e-01 | 0.000 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 9.997148e-01 | 0.000 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.997637e-01 | 0.000 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.997640e-01 | 0.000 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 9.997738e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.997738e-01 | 0.000 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 9.997890e-01 | 0.000 | 0 | 0 |
| Metabolic disorders of biological oxidation enzymes | R-HSA-5579029 | 9.997986e-01 | 0.000 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 9.998141e-01 | 0.000 | 0 | 0 |
| Glutathione conjugation | R-HSA-156590 | 9.998141e-01 | 0.000 | 0 | 0 |
| Mitochondrial Fatty Acid Beta-Oxidation | R-HSA-77289 | 9.998240e-01 | 0.000 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.998362e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.998432e-01 | 0.000 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.998585e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.998585e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.998729e-01 | 0.000 | 0 | 0 |
| Digestion and absorption | R-HSA-8963743 | 9.998729e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.998868e-01 | 0.000 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.998880e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.998934e-01 | 0.000 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 9.999115e-01 | 0.000 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 9.999234e-01 | 0.000 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.999325e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.999345e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999475e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.999476e-01 | 0.000 | 0 | 0 |
| Retinoid metabolism and transport | R-HSA-975634 | 9.999538e-01 | 0.000 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.999538e-01 | 0.000 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.999593e-01 | 0.000 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.999642e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999699e-01 | 0.000 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.999785e-01 | 0.000 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 9.999810e-01 | 0.000 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.999870e-01 | 0.000 | 0 | 0 |
| Metabolism of fat-soluble vitamins | R-HSA-6806667 | 9.999870e-01 | 0.000 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.999902e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999939e-01 | 0.000 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.999946e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999956e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999971e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999973e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999977e-01 | 0.000 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 9.999979e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.999985e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999985e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.999988e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.999992e-01 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 9.999992e-01 | 0.000 | 0 | 0 |
| Disease | R-HSA-1643685 | 9.999993e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999993e-01 | 0.000 | 0 | 0 |
| Translation | R-HSA-72766 | 9.999998e-01 | 0.000 | 0 | 0 |
| Post-translational protein modification | R-HSA-597592 | 9.999998e-01 | 0.000 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 9.999998e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999998e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999998e-01 | 0.000 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999999e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999999e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 1.000000e+00 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 1.000000e+00 | 0.000 | 0 | 0 |
| Regulation of Complement cascade | R-HSA-977606 | 1.000000e+00 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 1.000000e+00 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 1.000000e+00 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 1.000000e+00 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 1.000000e+00 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 1.000000e+00 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 1.000000e+00 | 0.000 | 0 | 0 |
| Complement cascade | R-HSA-166658 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 1.000000e+00 | 0.000 | 0 | 0 |
| Expression and translocation of olfactory receptors | R-HSA-9752946 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
| name | reactome_id | p | -log10p | ref_path | ref_path_lowest |
|---|---|---|---|---|---|
| Cell Cycle | R-HSA-1640170 | 3.552714e-15 | 14.449 | 0 | 0 |
| Cell Cycle, Mitotic | R-HSA-69278 | 4.440892e-15 | 14.353 | 0 | 0 |
| M Phase | R-HSA-68886 | 2.187139e-14 | 13.660 | 0 | 0 |
| Cellular response to heat stress | R-HSA-3371556 | 8.082424e-14 | 13.092 | 0 | 0 |
| HSF1-dependent transactivation | R-HSA-3371571 | 1.951217e-12 | 11.710 | 0 | 0 |
| Attenuation phase | R-HSA-3371568 | 9.355405e-12 | 11.029 | 0 | 0 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 8.514967e-12 | 11.070 | 0 | 0 |
| Membrane Trafficking | R-HSA-199991 | 2.858724e-11 | 10.544 | 0 | 0 |
| Cellular responses to stimuli | R-HSA-8953897 | 1.273692e-10 | 9.895 | 1 | 0 |
| Cellular responses to stress | R-HSA-2262752 | 5.881053e-10 | 9.231 | 1 | 0 |
| Translocation of SLC2A4 (GLUT4) to the plasma membrane | R-HSA-1445148 | 3.193332e-09 | 8.496 | 0 | 0 |
| Cell Cycle Checkpoints | R-HSA-69620 | 3.242943e-09 | 8.489 | 0 | 0 |
| Mitotic Anaphase | R-HSA-68882 | 4.604893e-09 | 8.337 | 0 | 0 |
| Mitotic Metaphase and Anaphase | R-HSA-2555396 | 5.321425e-09 | 8.274 | 0 | 0 |
| Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | R-HSA-8950505 | 5.060536e-09 | 8.296 | 0 | 0 |
| Mitotic Prophase | R-HSA-68875 | 1.151894e-08 | 7.939 | 0 | 0 |
| Recycling pathway of L1 | R-HSA-437239 | 2.501910e-08 | 7.602 | 0 | 0 |
| Interleukin-12 signaling | R-HSA-9020591 | 2.579618e-08 | 7.588 | 0 | 0 |
| Mitotic Prometaphase | R-HSA-68877 | 3.315928e-08 | 7.479 | 0 | 0 |
| Separation of Sister Chromatids | R-HSA-2467813 | 3.832394e-08 | 7.417 | 0 | 0 |
| HSF1 activation | R-HSA-3371511 | 3.725593e-08 | 7.429 | 0 | 0 |
| Estrogen-dependent gene expression | R-HSA-9018519 | 4.525573e-08 | 7.344 | 0 | 0 |
| Antiviral mechanism by IFN-stimulated genes | R-HSA-1169410 | 5.393773e-08 | 7.268 | 0 | 0 |
| Signal Transduction | R-HSA-162582 | 7.554186e-08 | 7.122 | 1 | 0 |
| Positive epigenetic regulation of rRNA expression | R-HSA-5250913 | 9.348633e-08 | 7.029 | 0 | 0 |
| Resolution of Sister Chromatid Cohesion | R-HSA-2500257 | 1.172392e-07 | 6.931 | 0 | 0 |
| Interleukin-12 family signaling | R-HSA-447115 | 1.245027e-07 | 6.905 | 0 | 0 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 1.921749e-07 | 6.716 | 0 | 0 |
| Axon guidance | R-HSA-422475 | 3.845260e-07 | 6.415 | 0 | 0 |
| Transcriptional regulation by small RNAs | R-HSA-5578749 | 4.080346e-07 | 6.389 | 0 | 0 |
| Formation of the beta-catenin:TCF transactivating complex | R-HSA-201722 | 5.841248e-07 | 6.233 | 0 | 0 |
| Nervous system development | R-HSA-9675108 | 6.274060e-07 | 6.202 | 0 | 0 |
| ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression | R-HSA-427389 | 6.503149e-07 | 6.187 | 0 | 0 |
| Kinesins | R-HSA-983189 | 9.604279e-07 | 6.018 | 0 | 0 |
| L1CAM interactions | R-HSA-373760 | 1.041853e-06 | 5.982 | 0 | 0 |
| G2/M Checkpoints | R-HSA-69481 | 1.030362e-06 | 5.987 | 0 | 0 |
| Regulation of PD-L1(CD274) transcription | R-HSA-9909649 | 1.157824e-06 | 5.936 | 0 | 0 |
| Diseases of signal transduction by growth factor receptors and second messengers | R-HSA-5663202 | 1.244476e-06 | 5.905 | 0 | 0 |
| Chromatin organization | R-HSA-4839726 | 1.527610e-06 | 5.816 | 0 | 0 |
| Vesicle-mediated transport | R-HSA-5653656 | 1.570815e-06 | 5.804 | 0 | 0 |
| EML4 and NUDC in mitotic spindle formation | R-HSA-9648025 | 1.699074e-06 | 5.770 | 0 | 0 |
| Nonhomologous End-Joining (NHEJ) | R-HSA-5693571 | 2.154122e-06 | 5.667 | 0 | 0 |
| B-WICH complex positively regulates rRNA expression | R-HSA-5250924 | 2.133893e-06 | 5.671 | 0 | 0 |
| Nuclear Envelope (NE) Reassembly | R-HSA-2995410 | 2.274207e-06 | 5.643 | 0 | 0 |
| Chromatin modifying enzymes | R-HSA-3247509 | 2.811845e-06 | 5.551 | 0 | 0 |
| Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) | R-HSA-9845323 | 3.291841e-06 | 5.483 | 0 | 0 |
| Nucleosome assembly | R-HSA-774815 | 3.628159e-06 | 5.440 | 0 | 0 |
| Deposition of new CENPA-containing nucleosomes at the centromere | R-HSA-606279 | 3.628159e-06 | 5.440 | 0 | 0 |
| ESR-mediated signaling | R-HSA-8939211 | 3.880213e-06 | 5.411 | 0 | 0 |
| COPI-dependent Golgi-to-ER retrograde traffic | R-HSA-6811434 | 8.856233e-06 | 5.053 | 0 | 0 |
| Post NMDA receptor activation events | R-HSA-438064 | 1.022758e-05 | 4.990 | 0 | 0 |
| HDACs deacetylate histones | R-HSA-3214815 | 1.176323e-05 | 4.929 | 0 | 0 |
| Diseases of programmed cell death | R-HSA-9645723 | 1.217950e-05 | 4.914 | 0 | 0 |
| Apoptotic cleavage of cellular proteins | R-HSA-111465 | 1.240249e-05 | 4.906 | 0 | 0 |
| Cell-Cell communication | R-HSA-1500931 | 1.572619e-05 | 4.803 | 0 | 0 |
| Regulation of MECP2 expression and activity | R-HSA-9022692 | 1.669119e-05 | 4.778 | 0 | 0 |
| Assembly and cell surface presentation of NMDA receptors | R-HSA-9609736 | 1.737419e-05 | 4.760 | 0 | 0 |
| Apoptotic execution phase | R-HSA-75153 | 1.680754e-05 | 4.774 | 0 | 0 |
| HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand | R-HSA-3371497 | 1.788717e-05 | 4.747 | 0 | 0 |
| Intra-Golgi and retrograde Golgi-to-ER traffic | R-HSA-6811442 | 2.446669e-05 | 4.611 | 0 | 0 |
| Regulation of CDH1 Gene Transcription | R-HSA-9764560 | 2.623849e-05 | 4.581 | 0 | 0 |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | R-HSA-5693565 | 2.768146e-05 | 4.558 | 0 | 0 |
| Transport of Mature mRNA Derived from an Intronless Transcript | R-HSA-159231 | 2.941669e-05 | 4.531 | 0 | 0 |
| Activation of BAD and translocation to mitochondria | R-HSA-111447 | 3.323965e-05 | 4.478 | 0 | 0 |
| Recruitment of NuMA to mitotic centrosomes | R-HSA-380320 | 3.321384e-05 | 4.479 | 0 | 0 |
| Negative Regulation of CDH1 Gene Transcription | R-HSA-9764725 | 3.389611e-05 | 4.470 | 0 | 0 |
| SARS-CoV-1 targets host intracellular signalling and regulatory pathways | R-HSA-9735871 | 3.323965e-05 | 4.478 | 0 | 0 |
| Transport of Mature mRNAs Derived from Intronless Transcripts | R-HSA-159234 | 3.782032e-05 | 4.422 | 0 | 0 |
| Aggrephagy | R-HSA-9646399 | 3.782032e-05 | 4.422 | 0 | 0 |
| HATs acetylate histones | R-HSA-3214847 | 3.743695e-05 | 4.427 | 0 | 0 |
| Mitotic Spindle Checkpoint | R-HSA-69618 | 4.347972e-05 | 4.362 | 0 | 0 |
| DNA Double Strand Break Response | R-HSA-5693606 | 4.379779e-05 | 4.359 | 0 | 0 |
| PRC2 methylates histones and DNA | R-HSA-212300 | 4.986609e-05 | 4.302 | 0 | 0 |
| RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function | R-HSA-8936459 | 5.266027e-05 | 4.279 | 0 | 0 |
| Processing of Capped Intron-Containing Pre-mRNA | R-HSA-72203 | 5.375509e-05 | 4.270 | 0 | 0 |
| PKR-mediated signaling | R-HSA-9833482 | 5.466811e-05 | 4.262 | 0 | 0 |
| Gene Silencing by RNA | R-HSA-211000 | 5.563378e-05 | 4.255 | 0 | 0 |
| Nuclear Envelope Breakdown | R-HSA-2980766 | 5.697138e-05 | 4.244 | 0 | 0 |
| Activation of NMDA receptors and postsynaptic events | R-HSA-442755 | 5.827049e-05 | 4.235 | 0 | 0 |
| COPI-mediated anterograde transport | R-HSA-6807878 | 6.060169e-05 | 4.218 | 0 | 0 |
| Apoptosis | R-HSA-109581 | 6.639653e-05 | 4.178 | 0 | 0 |
| Viral Infection Pathways | R-HSA-9824446 | 7.501496e-05 | 4.125 | 0 | 0 |
| Meiotic synapsis | R-HSA-1221632 | 7.846557e-05 | 4.105 | 0 | 0 |
| Golgi-to-ER retrograde transport | R-HSA-8856688 | 8.172468e-05 | 4.088 | 0 | 0 |
| Assembly of the pre-replicative complex | R-HSA-68867 | 8.450264e-05 | 4.073 | 0 | 0 |
| RNA Polymerase I Transcription | R-HSA-73864 | 1.059681e-04 | 3.975 | 0 | 0 |
| G2/M Transition | R-HSA-69275 | 1.023844e-04 | 3.990 | 0 | 0 |
| MHC class II antigen presentation | R-HSA-2132295 | 1.080434e-04 | 3.966 | 0 | 0 |
| Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex | R-HSA-9843970 | 1.090992e-04 | 3.962 | 0 | 0 |
| Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | R-HSA-190840 | 1.099305e-04 | 3.959 | 0 | 0 |
| Regulation of CDH1 Expression and Function | R-HSA-9764265 | 1.138491e-04 | 3.944 | 0 | 0 |
| Regulation of Expression and Function of Type I Classical Cadherins | R-HSA-9764274 | 1.138491e-04 | 3.944 | 0 | 0 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 1.247204e-04 | 3.904 | 0 | 0 |
| Interactions of Rev with host cellular proteins | R-HSA-177243 | 1.308731e-04 | 3.883 | 0 | 0 |
| HCMV Early Events | R-HSA-9609690 | 1.358143e-04 | 3.867 | 0 | 0 |
| Regulation of endogenous retroelements | R-HSA-9842860 | 1.420301e-04 | 3.848 | 0 | 0 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | R-HSA-389958 | 1.439211e-04 | 3.842 | 0 | 0 |
| Transport of connexons to the plasma membrane | R-HSA-190872 | 1.567361e-04 | 3.805 | 0 | 0 |
| Condensation of Prophase Chromosomes | R-HSA-2299718 | 1.823275e-04 | 3.739 | 0 | 0 |
| Signaling downstream of RAS mutants | R-HSA-9649948 | 1.823275e-04 | 3.739 | 0 | 0 |
| Paradoxical activation of RAF signaling by kinase inactive BRAF | R-HSA-6802955 | 1.823275e-04 | 3.739 | 0 | 0 |
| Signaling by moderate kinase activity BRAF mutants | R-HSA-6802946 | 1.823275e-04 | 3.739 | 0 | 0 |
| ISG15 antiviral mechanism | R-HSA-1169408 | 1.737984e-04 | 3.760 | 0 | 0 |
| DNA Replication Pre-Initiation | R-HSA-69002 | 1.733703e-04 | 3.761 | 0 | 0 |
| Signaling by RAS mutants | R-HSA-6802949 | 1.823275e-04 | 3.739 | 0 | 0 |
| Programmed Cell Death | R-HSA-5357801 | 1.765252e-04 | 3.753 | 0 | 0 |
| Muscle contraction | R-HSA-397014 | 1.727268e-04 | 3.763 | 0 | 0 |
| SARS-CoV-2 targets host intracellular signalling and regulatory pathways | R-HSA-9755779 | 1.770187e-04 | 3.752 | 0 | 0 |
| RNA Polymerase I Promoter Opening | R-HSA-73728 | 1.876389e-04 | 3.727 | 0 | 0 |
| Transport of Mature Transcript to Cytoplasm | R-HSA-72202 | 1.979391e-04 | 3.703 | 0 | 0 |
| Signaling by RAF1 mutants | R-HSA-9656223 | 2.033574e-04 | 3.692 | 0 | 0 |
| RNA Polymerase I Promoter Clearance | R-HSA-73854 | 2.035235e-04 | 3.691 | 0 | 0 |
| Transport of the SLBP independent Mature mRNA | R-HSA-159227 | 2.376677e-04 | 3.624 | 0 | 0 |
| Assembly of the ORC complex at the origin of replication | R-HSA-68616 | 2.376677e-04 | 3.624 | 0 | 0 |
| Prefoldin mediated transfer of substrate to CCT/TriC | R-HSA-389957 | 2.406848e-04 | 3.619 | 0 | 0 |
| Signaling by BRAF and RAF1 fusions | R-HSA-6802952 | 2.450395e-04 | 3.611 | 0 | 0 |
| Activation of AMPK downstream of NMDARs | R-HSA-9619483 | 2.451533e-04 | 3.611 | 0 | 0 |
| Regulation of Homotypic Cell-Cell Adhesion | R-HSA-9759476 | 2.648850e-04 | 3.577 | 0 | 0 |
| Rev-mediated nuclear export of HIV RNA | R-HSA-165054 | 2.781949e-04 | 3.556 | 0 | 0 |
| Post-chaperonin tubulin folding pathway | R-HSA-389977 | 3.015833e-04 | 3.521 | 0 | 0 |
| DNA methylation | R-HSA-5334118 | 3.170106e-04 | 3.499 | 0 | 0 |
| Transport of the SLBP Dependant Mature mRNA | R-HSA-159230 | 3.014855e-04 | 3.521 | 0 | 0 |
| Defective pyroptosis | R-HSA-9710421 | 3.082480e-04 | 3.511 | 0 | 0 |
| Formation of tubulin folding intermediates by CCT/TriC | R-HSA-389960 | 3.193077e-04 | 3.496 | 0 | 0 |
| Replacement of protamines by nucleosomes in the male pronucleus | R-HSA-9821993 | 3.193077e-04 | 3.496 | 0 | 0 |
| Gap junction trafficking and regulation | R-HSA-157858 | 3.282255e-04 | 3.484 | 0 | 0 |
| Transcriptional Regulation by MECP2 | R-HSA-8986944 | 3.347808e-04 | 3.475 | 0 | 0 |
| NS1 Mediated Effects on Host Pathways | R-HSA-168276 | 3.452861e-04 | 3.462 | 0 | 0 |
| Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | R-HSA-141444 | 3.541735e-04 | 3.451 | 0 | 0 |
| Amplification of signal from the kinetochores | R-HSA-141424 | 3.541735e-04 | 3.451 | 0 | 0 |
| MITF-M-regulated melanocyte development | R-HSA-9730414 | 3.566994e-04 | 3.448 | 0 | 0 |
| Gap junction trafficking | R-HSA-190828 | 3.762250e-04 | 3.425 | 0 | 0 |
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.885528e-04 | 3.411 | 1 | 0 |
| mRNA Splicing - Major Pathway | R-HSA-72163 | 4.239622e-04 | 3.373 | 0 | 0 |
| Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex | R-HSA-75035 | 4.169430e-04 | 3.380 | 0 | 0 |
| Inhibition of DNA recombination at telomere | R-HSA-9670095 | 4.257562e-04 | 3.371 | 0 | 0 |
| DNA Replication | R-HSA-69306 | 4.745361e-04 | 3.324 | 0 | 0 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 4.760088e-04 | 3.322 | 0 | 0 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 4.760088e-04 | 3.322 | 0 | 0 |
| Cell junction organization | R-HSA-446728 | 5.212090e-04 | 3.283 | 0 | 0 |
| ER to Golgi Anterograde Transport | R-HSA-199977 | 5.281780e-04 | 3.277 | 0 | 0 |
| Regulation of endogenous retroelements by KRAB-ZFP proteins | R-HSA-9843940 | 5.417788e-04 | 3.266 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in cell cycle and proliferation | R-HSA-9825892 | 5.444039e-04 | 3.264 | 0 | 0 |
| E3 ubiquitin ligases ubiquitinate target proteins | R-HSA-8866654 | 5.654763e-04 | 3.248 | 0 | 0 |
| Metabolism of RNA | R-HSA-8953854 | 5.793829e-04 | 3.237 | 0 | 0 |
| Late Phase of HIV Life Cycle | R-HSA-162599 | 6.490357e-04 | 3.188 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 6.479657e-04 | 3.188 | 0 | 0 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 6.510092e-04 | 3.186 | 0 | 0 |
| Regulation of localization of FOXO transcription factors | R-HSA-9614399 | 6.646821e-04 | 3.177 | 0 | 0 |
| Interferon Signaling | R-HSA-913531 | 6.922973e-04 | 3.160 | 0 | 0 |
| Packaging Of Telomere Ends | R-HSA-171306 | 6.952787e-04 | 3.158 | 0 | 0 |
| HIV Life Cycle | R-HSA-162587 | 6.965597e-04 | 3.157 | 0 | 0 |
| Clathrin-mediated endocytosis | R-HSA-8856828 | 7.162533e-04 | 3.145 | 0 | 0 |
| SIRT1 negatively regulates rRNA expression | R-HSA-427359 | 7.229125e-04 | 3.141 | 0 | 0 |
| Oncogenic MAPK signaling | R-HSA-6802957 | 7.441609e-04 | 3.128 | 0 | 0 |
| AURKA Activation by TPX2 | R-HSA-8854518 | 7.592201e-04 | 3.120 | 0 | 0 |
| Regulation of TP53 Activity through Acetylation | R-HSA-6804758 | 8.083888e-04 | 3.092 | 0 | 0 |
| Transport of Mature mRNA derived from an Intron-Containing Transcript | R-HSA-159236 | 8.398645e-04 | 3.076 | 0 | 0 |
| Reduction of cytosolic Ca++ levels | R-HSA-418359 | 9.882672e-04 | 3.005 | 0 | 0 |
| Chromosome Maintenance | R-HSA-73886 | 8.900237e-04 | 3.051 | 0 | 0 |
| Adherens junctions interactions | R-HSA-418990 | 9.769277e-04 | 3.010 | 0 | 0 |
| Striated Muscle Contraction | R-HSA-390522 | 1.000679e-03 | 3.000 | 0 | 0 |
| Transcriptional regulation by RUNX1 | R-HSA-8878171 | 1.009820e-03 | 2.996 | 0 | 0 |
| Factors involved in megakaryocyte development and platelet production | R-HSA-983231 | 1.037794e-03 | 2.984 | 0 | 0 |
| Processing of DNA double-strand break ends | R-HSA-5693607 | 1.037831e-03 | 2.984 | 0 | 0 |
| mRNA Splicing | R-HSA-72172 | 1.060467e-03 | 2.975 | 0 | 0 |
| The role of GTSE1 in G2/M progression after G2 checkpoint | R-HSA-8852276 | 1.065102e-03 | 2.973 | 0 | 0 |
| HIV Infection | R-HSA-162906 | 1.088603e-03 | 2.963 | 0 | 0 |
| TCF dependent signaling in response to WNT | R-HSA-201681 | 1.093070e-03 | 2.961 | 0 | 0 |
| HCMV Infection | R-HSA-9609646 | 1.094381e-03 | 2.961 | 0 | 0 |
| Protein ubiquitination | R-HSA-8852135 | 1.108878e-03 | 2.955 | 0 | 0 |
| Senescence-Associated Secretory Phenotype (SASP) | R-HSA-2559582 | 1.182509e-03 | 2.927 | 0 | 0 |
| Host Interactions of HIV factors | R-HSA-162909 | 1.214921e-03 | 2.915 | 0 | 0 |
| Nuclear import of Rev protein | R-HSA-180746 | 1.229546e-03 | 2.910 | 0 | 0 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 1.229546e-03 | 2.910 | 0 | 0 |
| Nephrin family interactions | R-HSA-373753 | 1.229575e-03 | 2.910 | 0 | 0 |
| Semaphorin interactions | R-HSA-373755 | 1.236125e-03 | 2.908 | 0 | 0 |
| Selective autophagy | R-HSA-9663891 | 1.241151e-03 | 2.906 | 0 | 0 |
| Epigenetic regulation of gene expression | R-HSA-212165 | 1.310945e-03 | 2.882 | 0 | 0 |
| SARS-CoV-1-host interactions | R-HSA-9692914 | 1.338269e-03 | 2.873 | 0 | 0 |
| Homology Directed Repair | R-HSA-5693538 | 1.350124e-03 | 2.870 | 0 | 0 |
| Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) | R-HSA-5619107 | 1.382919e-03 | 2.859 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | R-HSA-8939236 | 1.524125e-03 | 2.817 | 0 | 0 |
| HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) | R-HSA-5693567 | 1.498644e-03 | 2.824 | 0 | 0 |
| NoRC negatively regulates rRNA expression | R-HSA-427413 | 1.550982e-03 | 2.809 | 0 | 0 |
| Deubiquitination | R-HSA-5688426 | 1.551275e-03 | 2.809 | 0 | 0 |
| Chromatin modifications during the maternal to zygotic transition (MZT) | R-HSA-9821002 | 1.557878e-03 | 2.807 | 0 | 0 |
| Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | R-HSA-5625886 | 1.557878e-03 | 2.807 | 0 | 0 |
| NFE2L2 regulating MDR associated enzymes | R-HSA-9818032 | 1.589713e-03 | 2.799 | 0 | 0 |
| IP3 and IP4 transport between cytosol and nucleus | R-HSA-1855196 | 1.709041e-03 | 2.767 | 0 | 0 |
| IP6 and IP7 transport between cytosol and nucleus | R-HSA-1855229 | 1.709041e-03 | 2.767 | 0 | 0 |
| Meiosis | R-HSA-1500620 | 1.724271e-03 | 2.763 | 0 | 0 |
| Regulation of mRNA stability by proteins that bind AU-rich elements | R-HSA-450531 | 1.773478e-03 | 2.751 | 0 | 0 |
| DNA Double-Strand Break Repair | R-HSA-5693532 | 1.803176e-03 | 2.744 | 0 | 0 |
| Smooth Muscle Contraction | R-HSA-445355 | 1.806814e-03 | 2.743 | 0 | 0 |
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 2.022296e-03 | 2.694 | 0 | 0 |
| Negative epigenetic regulation of rRNA expression | R-HSA-5250941 | 2.120442e-03 | 2.674 | 0 | 0 |
| Vpr-mediated nuclear import of PICs | R-HSA-180910 | 2.189123e-03 | 2.660 | 0 | 0 |
| Cleavage of the damaged purine | R-HSA-110331 | 2.189123e-03 | 2.660 | 0 | 0 |
| S Phase | R-HSA-69242 | 2.210528e-03 | 2.656 | 0 | 0 |
| IPs transport between nucleus and cytosol | R-HSA-1855170 | 2.549712e-03 | 2.594 | 0 | 0 |
| Centrosome maturation | R-HSA-380287 | 2.608568e-03 | 2.584 | 0 | 0 |
| Sealing of the nuclear envelope (NE) by ESCRT-III | R-HSA-9668328 | 2.549712e-03 | 2.594 | 0 | 0 |
| Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA | R-HSA-428359 | 2.361778e-03 | 2.627 | 0 | 0 |
| Autophagy | R-HSA-9612973 | 2.329672e-03 | 2.633 | 0 | 0 |
| Depurination | R-HSA-73927 | 2.619947e-03 | 2.582 | 0 | 0 |
| Amyloid fiber formation | R-HSA-977225 | 2.396057e-03 | 2.621 | 0 | 0 |
| MITF-M-dependent gene expression | R-HSA-9856651 | 2.622606e-03 | 2.581 | 0 | 0 |
| Influenza Infection | R-HSA-168255 | 2.636110e-03 | 2.579 | 0 | 0 |
| DNA Damage/Telomere Stress Induced Senescence | R-HSA-2559586 | 2.657562e-03 | 2.576 | 0 | 0 |
| Transcriptional regulation of granulopoiesis | R-HSA-9616222 | 2.657562e-03 | 2.576 | 0 | 0 |
| Depolymerization of the Nuclear Lamina | R-HSA-4419969 | 2.771288e-03 | 2.557 | 0 | 0 |
| Signaling by EGFR | R-HSA-177929 | 2.822678e-03 | 2.549 | 0 | 0 |
| Regulation of Glucokinase by Glucokinase Regulatory Protein | R-HSA-170822 | 3.080519e-03 | 2.511 | 0 | 0 |
| Cell-cell junction organization | R-HSA-421270 | 3.343823e-03 | 2.476 | 0 | 0 |
| MECP2 regulates transcription of genes involved in GABA signaling | R-HSA-9022927 | 3.503739e-03 | 2.455 | 0 | 0 |
| Developmental Lineage of Mammary Gland Myoepithelial Cells | R-HSA-9927432 | 3.579041e-03 | 2.446 | 0 | 0 |
| Interactions of Vpr with host cellular proteins | R-HSA-176033 | 3.688375e-03 | 2.433 | 0 | 0 |
| RUNX3 regulates WNT signaling | R-HSA-8951430 | 3.845953e-03 | 2.415 | 0 | 0 |
| RNA Polymerase I Promoter Escape | R-HSA-73772 | 3.974931e-03 | 2.401 | 0 | 0 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.066761e-03 | 2.391 | 1 | 1 |
| Neurodegenerative Diseases | R-HSA-8863678 | 4.085785e-03 | 2.389 | 0 | 0 |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | R-HSA-8862803 | 4.085785e-03 | 2.389 | 0 | 0 |
| Export of Viral Ribonucleoproteins from Nucleus | R-HSA-168274 | 4.185741e-03 | 2.378 | 0 | 0 |
| Activation of BH3-only proteins | R-HSA-114452 | 4.341729e-03 | 2.362 | 0 | 0 |
| Nuclear Pore Complex (NPC) Disassembly | R-HSA-3301854 | 4.407542e-03 | 2.356 | 0 | 0 |
| Negative regulation of MET activity | R-HSA-6807004 | 4.539059e-03 | 2.343 | 0 | 0 |
| NFE2L2 regulates pentose phosphate pathway genes | R-HSA-9818028 | 4.710508e-03 | 2.327 | 0 | 0 |
| EPH-Ephrin signaling | R-HSA-2682334 | 4.752932e-03 | 2.323 | 0 | 0 |
| Regulation of PD-L1(CD274) expression | R-HSA-9909648 | 4.895849e-03 | 2.310 | 0 | 0 |
| Sema4D in semaphorin signaling | R-HSA-400685 | 5.027735e-03 | 2.299 | 0 | 0 |
| Signaling by WNT | R-HSA-195721 | 5.079302e-03 | 2.294 | 0 | 0 |
| Ub-specific processing proteases | R-HSA-5689880 | 5.266500e-03 | 2.278 | 0 | 0 |
| Chaperonin-mediated protein folding | R-HSA-390466 | 5.292364e-03 | 2.276 | 0 | 0 |
| Formation of annular gap junctions | R-HSA-196025 | 5.707060e-03 | 2.244 | 0 | 0 |
| MECP2 regulates neuronal receptors and channels | R-HSA-9022699 | 6.129901e-03 | 2.213 | 0 | 0 |
| TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | R-HSA-6804114 | 6.227188e-03 | 2.206 | 0 | 0 |
| Signaling by high-kinase activity BRAF mutants | R-HSA-6802948 | 6.153074e-03 | 2.211 | 0 | 0 |
| Deactivation of the beta-catenin transactivating complex | R-HSA-3769402 | 6.153074e-03 | 2.211 | 0 | 0 |
| COPI-independent Golgi-to-ER retrograde traffic | R-HSA-6811436 | 5.997247e-03 | 2.222 | 0 | 0 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 5.921886e-03 | 2.228 | 0 | 0 |
| Depyrimidination | R-HSA-73928 | 5.921886e-03 | 2.228 | 0 | 0 |
| Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.414121e-03 | 2.193 | 0 | 0 |
| GTP hydrolysis and joining of the 60S ribosomal subunit | R-HSA-72706 | 6.766192e-03 | 2.170 | 0 | 0 |
| Ion homeostasis | R-HSA-5578775 | 6.830081e-03 | 2.166 | 0 | 0 |
| Negative regulation of NMDA receptor-mediated neuronal transmission | R-HSA-9617324 | 7.066200e-03 | 2.151 | 0 | 0 |
| Macroautophagy | R-HSA-1632852 | 7.200417e-03 | 2.143 | 0 | 0 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 7.205136e-03 | 2.142 | 0 | 0 |
| Defective Intrinsic Pathway for Apoptosis | R-HSA-9734009 | 7.409175e-03 | 2.130 | 0 | 0 |
| Signaling by Hippo | R-HSA-2028269 | 7.919816e-03 | 2.101 | 0 | 0 |
| Cargo trafficking to the periciliary membrane | R-HSA-5620920 | 8.090382e-03 | 2.092 | 0 | 0 |
| HuR (ELAVL1) binds and stabilizes mRNA | R-HSA-450520 | 8.126510e-03 | 2.090 | 0 | 0 |
| Gap junction degradation | R-HSA-190873 | 8.126510e-03 | 2.090 | 0 | 0 |
| Response of endothelial cells to shear stress | R-HSA-9860931 | 8.341758e-03 | 2.079 | 0 | 0 |
| Meiotic recombination | R-HSA-912446 | 8.437582e-03 | 2.074 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex | R-HSA-170834 | 8.571010e-03 | 2.067 | 0 | 0 |
| Cellular Senescence | R-HSA-2559583 | 8.577720e-03 | 2.067 | 1 | 0 |
| FGFR2 alternative splicing | R-HSA-6803529 | 8.670588e-03 | 2.062 | 0 | 0 |
| NEP/NS2 Interacts with the Cellular Export Machinery | R-HSA-168333 | 9.112555e-03 | 2.040 | 0 | 0 |
| Reproduction | R-HSA-1474165 | 9.208744e-03 | 2.036 | 0 | 0 |
| Protein folding | R-HSA-391251 | 9.644120e-03 | 2.016 | 0 | 0 |
| snRNP Assembly | R-HSA-191859 | 9.892798e-03 | 2.005 | 0 | 0 |
| Metabolism of non-coding RNA | R-HSA-194441 | 9.892798e-03 | 2.005 | 0 | 0 |
| Chaperone Mediated Autophagy | R-HSA-9613829 | 9.929420e-03 | 2.003 | 0 | 0 |
| Gap junction assembly | R-HSA-190861 | 1.025536e-02 | 1.989 | 0 | 0 |
| Signaling by VEGF | R-HSA-194138 | 1.041982e-02 | 1.982 | 1 | 0 |
| Constitutive Signaling by AKT1 E17K in Cancer | R-HSA-5674400 | 1.053272e-02 | 1.977 | 0 | 0 |
| Estrogen-dependent nuclear events downstream of ESR-membrane signaling | R-HSA-9634638 | 1.053272e-02 | 1.977 | 0 | 0 |
| Formation of the polybromo-BAF (pBAF) complex | R-HSA-9933939 | 1.094466e-02 | 1.961 | 0 | 0 |
| Establishment of Sister Chromatid Cohesion | R-HSA-2468052 | 1.117812e-02 | 1.952 | 0 | 0 |
| CaMK IV-mediated phosphorylation of CREB | R-HSA-111932 | 1.117812e-02 | 1.952 | 0 | 0 |
| VEGFR2 mediated vascular permeability | R-HSA-5218920 | 1.123586e-02 | 1.949 | 0 | 0 |
| Transport of Ribonucleoproteins into the Host Nucleus | R-HSA-168271 | 1.123586e-02 | 1.949 | 0 | 0 |
| Glycolysis | R-HSA-70171 | 1.124898e-02 | 1.949 | 0 | 0 |
| Cellular responses to mechanical stimuli | R-HSA-9855142 | 1.136190e-02 | 1.945 | 0 | 0 |
| Regulation of T cell activation by CD28 family | R-HSA-388841 | 1.151793e-02 | 1.939 | 0 | 0 |
| CaM pathway | R-HSA-111997 | 1.385269e-02 | 1.858 | 0 | 0 |
| Calmodulin induced events | R-HSA-111933 | 1.385269e-02 | 1.858 | 0 | 0 |
| MAP2K and MAPK activation | R-HSA-5674135 | 1.290275e-02 | 1.889 | 0 | 0 |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | R-HSA-9860927 | 1.195221e-02 | 1.923 | 0 | 0 |
| L13a-mediated translational silencing of Ceruloplasmin expression | R-HSA-156827 | 1.285770e-02 | 1.891 | 0 | 0 |
| Signaling by ALK fusions and activated point mutants | R-HSA-9725370 | 1.182631e-02 | 1.927 | 0 | 0 |
| Signaling by ALK in cancer | R-HSA-9700206 | 1.182631e-02 | 1.927 | 0 | 0 |
| Platelet degranulation | R-HSA-114608 | 1.216622e-02 | 1.915 | 0 | 0 |
| Signaling by ROBO receptors | R-HSA-376176 | 1.343543e-02 | 1.872 | 0 | 0 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 1.228468e-02 | 1.911 | 0 | 0 |
| SARS-CoV Infections | R-HSA-9679506 | 1.351497e-02 | 1.869 | 0 | 0 |
| InlB-mediated entry of Listeria monocytogenes into host cell | R-HSA-8875360 | 1.392984e-02 | 1.856 | 0 | 0 |
| Cell-extracellular matrix interactions | R-HSA-446353 | 1.392984e-02 | 1.856 | 0 | 0 |
| EGFR downregulation | R-HSA-182971 | 1.464476e-02 | 1.834 | 0 | 0 |
| Formation of the dystrophin-glycoprotein complex (DGC) | R-HSA-9913351 | 1.464476e-02 | 1.834 | 0 | 0 |
| Ca-dependent events | R-HSA-111996 | 1.475076e-02 | 1.831 | 0 | 0 |
| SARS-CoV-2-host interactions | R-HSA-9705683 | 1.482275e-02 | 1.829 | 0 | 0 |
| Loss of MECP2 binding ability to 5mC-DNA | R-HSA-9022538 | 1.486176e-02 | 1.828 | 0 | 0 |
| Sema4D induced cell migration and growth-cone collapse | R-HSA-416572 | 1.502377e-02 | 1.823 | 0 | 0 |
| SWI/SNF chromatin remodelers | R-HSA-9932451 | 1.512130e-02 | 1.820 | 0 | 0 |
| ATP-dependent chromatin remodelers | R-HSA-9932444 | 1.512130e-02 | 1.820 | 0 | 0 |
| TGFBR3 expression | R-HSA-9839394 | 1.512130e-02 | 1.820 | 0 | 0 |
| NRAGE signals death through JNK | R-HSA-193648 | 1.551988e-02 | 1.809 | 0 | 0 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 1.551988e-02 | 1.809 | 0 | 0 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 1.562273e-02 | 1.806 | 0 | 0 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 1.562273e-02 | 1.806 | 0 | 0 |
| Pre-NOTCH Transcription and Translation | R-HSA-1912408 | 1.569670e-02 | 1.804 | 0 | 0 |
| Cilium Assembly | R-HSA-5617833 | 1.612615e-02 | 1.792 | 0 | 0 |
| Signaling by Nuclear Receptors | R-HSA-9006931 | 1.618212e-02 | 1.791 | 0 | 0 |
| Transcriptional regulation by RUNX3 | R-HSA-8878159 | 1.648688e-02 | 1.783 | 0 | 0 |
| Telomere Maintenance | R-HSA-157579 | 1.648688e-02 | 1.783 | 0 | 0 |
| Diseases of mitotic cell cycle | R-HSA-9675126 | 1.707040e-02 | 1.768 | 0 | 0 |
| Signaling by TGFB family members | R-HSA-9006936 | 1.708719e-02 | 1.767 | 0 | 0 |
| Activation of HOX genes during differentiation | R-HSA-5619507 | 1.715690e-02 | 1.766 | 0 | 0 |
| Activation of anterior HOX genes in hindbrain development during early embryogenesis | R-HSA-5617472 | 1.715690e-02 | 1.766 | 0 | 0 |
| Ion transport by P-type ATPases | R-HSA-936837 | 1.728073e-02 | 1.762 | 0 | 0 |
| Regulation of CDH1 Function | R-HSA-9764561 | 1.736279e-02 | 1.760 | 0 | 0 |
| Postmitotic nuclear pore complex (NPC) reformation | R-HSA-9615933 | 1.789222e-02 | 1.747 | 0 | 0 |
| Diseases of Telomere Maintenance | R-HSA-9673013 | 1.793805e-02 | 1.746 | 0 | 0 |
| Alternative Lengthening of Telomeres (ALT) | R-HSA-9006821 | 1.793805e-02 | 1.746 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere | R-HSA-9670621 | 1.793805e-02 | 1.746 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations | R-HSA-9670615 | 1.793805e-02 | 1.746 | 0 | 0 |
| Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations | R-HSA-9670613 | 1.793805e-02 | 1.746 | 0 | 0 |
| Loss of MECP2 binding ability to 5hmC-DNA | R-HSA-9022534 | 1.793805e-02 | 1.746 | 0 | 0 |
| Signaling by NOTCH | R-HSA-157118 | 1.817533e-02 | 1.741 | 0 | 0 |
| Adaptive Immune System | R-HSA-1280218 | 1.846496e-02 | 1.734 | 0 | 0 |
| trans-Golgi Network Vesicle Budding | R-HSA-199992 | 1.879837e-02 | 1.726 | 0 | 0 |
| Platelet activation, signaling and aggregation | R-HSA-76002 | 1.897423e-02 | 1.722 | 0 | 0 |
| Pre-NOTCH Expression and Processing | R-HSA-1912422 | 1.913268e-02 | 1.718 | 0 | 0 |
| Epigenetic regulation by WDR5-containing histone modifying complexes | R-HSA-9917777 | 1.934089e-02 | 1.714 | 0 | 0 |
| Mitotic Telophase/Cytokinesis | R-HSA-68884 | 1.944198e-02 | 1.711 | 0 | 0 |
| Cohesin Loading onto Chromatin | R-HSA-2470946 | 1.974767e-02 | 1.704 | 0 | 0 |
| CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling | R-HSA-442742 | 1.977684e-02 | 1.704 | 0 | 0 |
| Influenza Viral RNA Transcription and Replication | R-HSA-168273 | 2.061205e-02 | 1.686 | 0 | 0 |
| Cell death signalling via NRAGE, NRIF and NADE | R-HSA-204998 | 2.069819e-02 | 1.684 | 0 | 0 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 2.100934e-02 | 1.678 | 0 | 0 |
| TLR3-mediated TICAM1-dependent programmed cell death | R-HSA-9013957 | 2.385798e-02 | 1.622 | 0 | 0 |
| AKT phosphorylates targets in the cytosol | R-HSA-198323 | 2.476654e-02 | 1.606 | 0 | 0 |
| Pervasive developmental disorders | R-HSA-9005895 | 2.476654e-02 | 1.606 | 0 | 0 |
| Disorders of Nervous System Development | R-HSA-9697154 | 2.476654e-02 | 1.606 | 0 | 0 |
| Loss of function of MECP2 in Rett syndrome | R-HSA-9005891 | 2.476654e-02 | 1.606 | 0 | 0 |
| Disorders of Developmental Biology | R-HSA-9675151 | 2.151421e-02 | 1.667 | 0 | 0 |
| Unblocking of NMDA receptors, glutamate binding and activation | R-HSA-438066 | 2.174813e-02 | 1.663 | 0 | 0 |
| Formation of a pool of free 40S subunits | R-HSA-72689 | 2.594820e-02 | 1.586 | 0 | 0 |
| Listeria monocytogenes entry into host cells | R-HSA-8876384 | 2.174813e-02 | 1.663 | 0 | 0 |
| RAF activation | R-HSA-5673000 | 2.609632e-02 | 1.583 | 0 | 0 |
| Golgi Associated Vesicle Biogenesis | R-HSA-432722 | 2.418093e-02 | 1.617 | 0 | 0 |
| mTORC1-mediated signalling | R-HSA-166208 | 2.578922e-02 | 1.589 | 0 | 0 |
| Maternal to zygotic transition (MZT) | R-HSA-9816359 | 2.601230e-02 | 1.585 | 0 | 0 |
| Viral Messenger RNA Synthesis | R-HSA-168325 | 2.642258e-02 | 1.578 | 0 | 0 |
| Signaling by Receptor Tyrosine Kinases | R-HSA-9006934 | 2.189753e-02 | 1.660 | 1 | 0 |
| MAPK family signaling cascades | R-HSA-5683057 | 2.423685e-02 | 1.616 | 0 | 0 |
| Initiation of Nuclear Envelope (NE) Reformation | R-HSA-2995383 | 2.174813e-02 | 1.663 | 0 | 0 |
| Signaling by Interleukins | R-HSA-449147 | 2.418968e-02 | 1.616 | 1 | 0 |
| Apoptotic cleavage of cell adhesion proteins | R-HSA-351906 | 2.674999e-02 | 1.573 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence | R-HSA-9825895 | 2.674999e-02 | 1.573 | 0 | 0 |
| PKMTs methylate histone lysines | R-HSA-3214841 | 2.688593e-02 | 1.570 | 0 | 0 |
| Transcriptional Regulation by VENTX | R-HSA-8853884 | 2.688593e-02 | 1.570 | 0 | 0 |
| Base Excision Repair | R-HSA-73884 | 2.723320e-02 | 1.565 | 0 | 0 |
| SARS-CoV-1 Infection | R-HSA-9678108 | 2.761591e-02 | 1.559 | 0 | 0 |
| Co-inhibition by PD-1 | R-HSA-389948 | 2.826345e-02 | 1.549 | 0 | 0 |
| Opioid Signalling | R-HSA-111885 | 2.870490e-02 | 1.542 | 0 | 0 |
| Cargo recognition for clathrin-mediated endocytosis | R-HSA-8856825 | 2.870490e-02 | 1.542 | 0 | 0 |
| tRNA processing in the nucleus | R-HSA-6784531 | 2.914826e-02 | 1.535 | 0 | 0 |
| Formation of WDR5-containing histone-modifying complexes | R-HSA-9772755 | 2.973961e-02 | 1.527 | 0 | 0 |
| Intraflagellar transport | R-HSA-5620924 | 3.026462e-02 | 1.519 | 0 | 0 |
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 3.090413e-02 | 1.510 | 0 | 0 |
| NFE2L2 regulating tumorigenic genes | R-HSA-9818030 | 3.094595e-02 | 1.509 | 0 | 0 |
| Transport to the Golgi and subsequent modification | R-HSA-948021 | 3.137461e-02 | 1.503 | 0 | 0 |
| G alpha (12/13) signalling events | R-HSA-416482 | 3.244117e-02 | 1.489 | 0 | 0 |
| Downregulation of ERBB2 signaling | R-HSA-8863795 | 3.263219e-02 | 1.486 | 0 | 0 |
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | R-HSA-2173793 | 3.300641e-02 | 1.481 | 0 | 0 |
| Sensory processing of sound by outer hair cells of the cochlea | R-HSA-9662361 | 3.300641e-02 | 1.481 | 0 | 0 |
| FLT3 signaling in disease | R-HSA-9682385 | 3.372390e-02 | 1.472 | 0 | 0 |
| ALK mutants bind TKIs | R-HSA-9700645 | 3.506351e-02 | 1.455 | 0 | 0 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 3.516519e-02 | 1.454 | 0 | 0 |
| Loss of Function of TGFBR1 in Cancer | R-HSA-3656534 | 3.521077e-02 | 1.453 | 0 | 0 |
| Loss of phosphorylation of MECP2 at T308 | R-HSA-9022535 | 3.521077e-02 | 1.453 | 0 | 0 |
| LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production | R-HSA-3134973 | 3.521077e-02 | 1.453 | 0 | 0 |
| Developmental Biology | R-HSA-1266738 | 3.543289e-02 | 1.451 | 0 | 0 |
| Developmental Lineages of the Mammary Gland | R-HSA-9924644 | 3.694128e-02 | 1.432 | 0 | 0 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 3.744160e-02 | 1.427 | 0 | 0 |
| HCMV Late Events | R-HSA-9610379 | 3.760647e-02 | 1.425 | 0 | 0 |
| Interactions of Tat with host cellular proteins | R-HSA-176034 | 3.778269e-02 | 1.423 | 0 | 0 |
| Breakdown of the nuclear lamina | R-HSA-352238 | 3.778269e-02 | 1.423 | 0 | 0 |
| Hedgehog 'off' state | R-HSA-5610787 | 3.780461e-02 | 1.422 | 0 | 0 |
| Signaling by MET | R-HSA-6806834 | 3.829131e-02 | 1.417 | 0 | 0 |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | R-HSA-9856530 | 3.829131e-02 | 1.417 | 0 | 0 |
| Potential therapeutics for SARS | R-HSA-9679191 | 4.017755e-02 | 1.396 | 0 | 0 |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | R-HSA-9705671 | 4.052624e-02 | 1.392 | 0 | 0 |
| Long-term potentiation | R-HSA-9620244 | 4.089974e-02 | 1.388 | 0 | 0 |
| HDMs demethylate histones | R-HSA-3214842 | 4.089974e-02 | 1.388 | 0 | 0 |
| EPHB-mediated forward signaling | R-HSA-3928662 | 4.230127e-02 | 1.374 | 0 | 0 |
| DNA strand elongation | R-HSA-69190 | 4.244260e-02 | 1.372 | 0 | 0 |
| Oxidative Stress Induced Senescence | R-HSA-2559580 | 4.351207e-02 | 1.361 | 1 | 1 |
| Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) | R-HSA-9934037 | 4.407021e-02 | 1.356 | 0 | 0 |
| MET activates RAP1 and RAC1 | R-HSA-8875555 | 4.471199e-02 | 1.350 | 0 | 0 |
| mRNA 3'-end processing | R-HSA-72187 | 4.557118e-02 | 1.341 | 0 | 0 |
| Formation of RNA Pol II elongation complex | R-HSA-112382 | 4.557118e-02 | 1.341 | 0 | 0 |
| Processive synthesis on the lagging strand | R-HSA-69183 | 4.598964e-02 | 1.337 | 0 | 0 |
| Sema3A PAK dependent Axon repulsion | R-HSA-399954 | 4.598964e-02 | 1.337 | 0 | 0 |
| Formation of the embryonic stem cell BAF (esBAF) complex | R-HSA-9933946 | 4.598964e-02 | 1.337 | 0 | 0 |
| Protein methylation | R-HSA-8876725 | 4.598964e-02 | 1.337 | 0 | 0 |
| DAG and IP3 signaling | R-HSA-1489509 | 4.693810e-02 | 1.328 | 0 | 0 |
| Non-integrin membrane-ECM interactions | R-HSA-3000171 | 4.737020e-02 | 1.324 | 0 | 0 |
| Transcriptional Regulation by E2F6 | R-HSA-8953750 | 4.784299e-02 | 1.320 | 0 | 0 |
| Signaling by ERBB2 | R-HSA-1227986 | 4.805871e-02 | 1.318 | 0 | 0 |
| Drug resistance in ERBB2 KD mutants | R-HSA-9665230 | 6.291595e-02 | 1.201 | 0 | 0 |
| Drug-mediated inhibition of ERBB2 signaling | R-HSA-9652282 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to AEE788 | R-HSA-9665250 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to lapatinib | R-HSA-9665251 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to neratinib | R-HSA-9665246 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to tesevatinib | R-HSA-9665245 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to osimertinib | R-HSA-9665247 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to trastuzumab | R-HSA-9665233 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to sapitinib | R-HSA-9665244 | 6.291595e-02 | 1.201 | 0 | 0 |
| Drug resistance in ERBB2 TMD/JMD mutants | R-HSA-9665737 | 6.291595e-02 | 1.201 | 0 | 0 |
| Resistance of ERBB2 KD mutants to afatinib | R-HSA-9665249 | 6.291595e-02 | 1.201 | 0 | 0 |
| Loss of MECP2 binding ability to the NCoR/SMRT complex | R-HSA-9022537 | 4.886947e-02 | 1.311 | 0 | 0 |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | R-HSA-354194 | 5.488890e-02 | 1.261 | 0 | 0 |
| Phosphorylation of the APC/C | R-HSA-176412 | 5.488890e-02 | 1.261 | 0 | 0 |
| Aberrant regulation of mitotic exit in cancer due to RB1 defects | R-HSA-9687136 | 5.488890e-02 | 1.261 | 0 | 0 |
| TRAF3-dependent IRF activation pathway | R-HSA-918233 | 6.471330e-02 | 1.189 | 0 | 0 |
| Ras activation upon Ca2+ influx through NMDA receptor | R-HSA-442982 | 5.940480e-02 | 1.226 | 0 | 0 |
| EPHA-mediated growth cone collapse | R-HSA-3928663 | 5.363431e-02 | 1.271 | 0 | 0 |
| Carboxyterminal post-translational modifications of tubulin | R-HSA-8955332 | 5.720938e-02 | 1.243 | 0 | 0 |
| RNA Polymerase II Transcription Elongation | R-HSA-75955 | 5.009881e-02 | 1.300 | 0 | 0 |
| Translation initiation complex formation | R-HSA-72649 | 5.492059e-02 | 1.260 | 0 | 0 |
| Nuclear events mediated by NFE2L2 | R-HSA-9759194 | 6.312812e-02 | 1.200 | 0 | 0 |
| Synthesis of DNA | R-HSA-69239 | 6.430110e-02 | 1.192 | 0 | 0 |
| PLC beta mediated events | R-HSA-112043 | 5.245456e-02 | 1.280 | 0 | 0 |
| Intracellular signaling by second messengers | R-HSA-9006925 | 5.440560e-02 | 1.264 | 0 | 0 |
| Neurotransmitter receptors and postsynaptic signal transmission | R-HSA-112314 | 5.337818e-02 | 1.273 | 0 | 0 |
| Regulation of cytoskeletal remodeling and cell spreading by IPP complex components | R-HSA-446388 | 4.886947e-02 | 1.311 | 0 | 0 |
| Inactivation of APC/C via direct inhibition of the APC/C complex | R-HSA-141430 | 6.471330e-02 | 1.189 | 0 | 0 |
| Retrograde transport at the Trans-Golgi-Network | R-HSA-6811440 | 5.720938e-02 | 1.243 | 0 | 0 |
| Rab regulation of trafficking | R-HSA-9007101 | 4.970453e-02 | 1.304 | 0 | 0 |
| Signaling by TGFBR3 | R-HSA-9839373 | 5.190521e-02 | 1.285 | 0 | 0 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 6.339883e-02 | 1.198 | 0 | 0 |
| RUNX2 regulates genes involved in cell migration | R-HSA-8941332 | 5.569651e-02 | 1.254 | 0 | 0 |
| Sensory processing of sound by inner hair cells of the cochlea | R-HSA-9662360 | 4.991529e-02 | 1.302 | 0 | 0 |
| Transcriptional and post-translational regulation of MITF-M expression and activity | R-HSA-9856649 | 6.339873e-02 | 1.198 | 0 | 0 |
| MAPK6/MAPK4 signaling | R-HSA-5687128 | 5.615353e-02 | 1.251 | 0 | 0 |
| TP53 Regulates Transcription of DNA Repair Genes | R-HSA-6796648 | 5.969383e-02 | 1.224 | 0 | 0 |
| Glucose metabolism | R-HSA-70326 | 4.970453e-02 | 1.304 | 0 | 0 |
| Immune System | R-HSA-168256 | 5.495230e-02 | 1.260 | 1 | 0 |
| Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | R-HSA-141405 | 6.471330e-02 | 1.189 | 0 | 0 |
| Mitochondrial unfolded protein response (UPRmt) | R-HSA-9841251 | 5.363431e-02 | 1.271 | 0 | 0 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 6.468072e-02 | 1.189 | 0 | 0 |
| IRE1alpha activates chaperones | R-HSA-381070 | 5.660360e-02 | 1.247 | 0 | 0 |
| Regulation of NFE2L2 gene expression | R-HSA-9818749 | 6.472455e-02 | 1.189 | 0 | 0 |
| Signaling by TGF-beta Receptor Complex in Cancer | R-HSA-3304351 | 6.472455e-02 | 1.189 | 0 | 0 |
| CREB phosphorylation | R-HSA-199920 | 6.472455e-02 | 1.189 | 0 | 0 |
| Ribosomal scanning and start codon recognition | R-HSA-72702 | 6.546781e-02 | 1.184 | 0 | 0 |
| KEAP1-NFE2L2 pathway | R-HSA-9755511 | 6.609141e-02 | 1.180 | 0 | 0 |
| TICAM1-dependent activation of IRF3/IRF7 | R-HSA-9013973 | 6.799757e-02 | 1.168 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperone genes | R-HSA-381183 | 6.799757e-02 | 1.168 | 0 | 0 |
| Downregulation of TGF-beta receptor signaling | R-HSA-2173788 | 6.812491e-02 | 1.167 | 0 | 0 |
| DARPP-32 events | R-HSA-180024 | 6.860009e-02 | 1.164 | 0 | 0 |
| Endosomal Sorting Complex Required For Transport (ESCRT) | R-HSA-917729 | 6.860009e-02 | 1.164 | 0 | 0 |
| Late endosomal microautophagy | R-HSA-9615710 | 6.860009e-02 | 1.164 | 0 | 0 |
| Platelet calcium homeostasis | R-HSA-418360 | 6.860009e-02 | 1.164 | 0 | 0 |
| TP53 Regulates Transcription of Cell Cycle Genes | R-HSA-6791312 | 7.120176e-02 | 1.148 | 0 | 0 |
| MTOR signalling | R-HSA-165159 | 7.206085e-02 | 1.142 | 0 | 0 |
| RNA Polymerase I Transcription Initiation | R-HSA-73762 | 7.206085e-02 | 1.142 | 0 | 0 |
| Respiratory Syncytial Virus Infection Pathway | R-HSA-9820952 | 7.219753e-02 | 1.141 | 0 | 0 |
| Switching of origins to a post-replicative state | R-HSA-69052 | 7.361827e-02 | 1.133 | 0 | 0 |
| DNA Repair | R-HSA-73894 | 7.438393e-02 | 1.129 | 0 | 0 |
| Lysosome Vesicle Biogenesis | R-HSA-432720 | 7.487915e-02 | 1.126 | 0 | 0 |
| AUF1 (hnRNP D0) binds and destabilizes mRNA | R-HSA-450408 | 7.487915e-02 | 1.126 | 0 | 0 |
| Constitutive Signaling by EGFRvIII | R-HSA-5637810 | 7.545617e-02 | 1.122 | 0 | 0 |
| Signaling by EGFRvIII in Cancer | R-HSA-5637812 | 7.545617e-02 | 1.122 | 0 | 0 |
| Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | R-HSA-176407 | 7.545617e-02 | 1.122 | 0 | 0 |
| Death Receptor Signaling | R-HSA-73887 | 7.667629e-02 | 1.115 | 0 | 0 |
| Aberrant regulation of mitotic cell cycle due to RB1 defects | R-HSA-9687139 | 7.693090e-02 | 1.114 | 0 | 0 |
| Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | R-HSA-72662 | 7.724678e-02 | 1.112 | 0 | 0 |
| Gene expression (Transcription) | R-HSA-74160 | 7.838708e-02 | 1.106 | 0 | 0 |
| RNA Polymerase II Pre-transcription Events | R-HSA-674695 | 7.910603e-02 | 1.102 | 0 | 0 |
| Signaling by NOTCH4 | R-HSA-9013694 | 7.910603e-02 | 1.102 | 0 | 0 |
| TBC/RABGAPs | R-HSA-8854214 | 7.911657e-02 | 1.102 | 0 | 0 |
| TGF-beta receptor signaling activates SMADs | R-HSA-2173789 | 7.911657e-02 | 1.102 | 0 | 0 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 7.998184e-02 | 1.097 | 0 | 0 |
| RUNX3 regulates NOTCH signaling | R-HSA-8941856 | 8.157749e-02 | 1.088 | 0 | 0 |
| Constitutive Signaling by Overexpressed ERBB2 | R-HSA-9634285 | 8.157749e-02 | 1.088 | 0 | 0 |
| Response of EIF2AK4 (GCN2) to amino acid deficiency | R-HSA-9633012 | 8.254354e-02 | 1.083 | 0 | 0 |
| Binding of TCF/LEF:CTNNB1 to target gene promoters | R-HSA-4411364 | 8.262390e-02 | 1.083 | 0 | 0 |
| TRIF-mediated programmed cell death | R-HSA-2562578 | 8.262390e-02 | 1.083 | 0 | 0 |
| SOS-mediated signalling | R-HSA-112412 | 8.262390e-02 | 1.083 | 0 | 0 |
| SHOC2 M1731 mutant abolishes MRAS complex function | R-HSA-9726840 | 8.262390e-02 | 1.083 | 0 | 0 |
| Uptake and function of diphtheria toxin | R-HSA-5336415 | 8.262390e-02 | 1.083 | 0 | 0 |
| SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | R-HSA-2173796 | 8.277221e-02 | 1.082 | 0 | 0 |
| Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes | R-HSA-9851695 | 8.317971e-02 | 1.080 | 0 | 0 |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | R-HSA-9841922 | 8.317971e-02 | 1.080 | 0 | 0 |
| Epigenetic regulation of gene expression by MLL3 and MLL4 complexes | R-HSA-9818564 | 8.317971e-02 | 1.080 | 0 | 0 |
| G-protein mediated events | R-HSA-112040 | 8.452459e-02 | 1.073 | 0 | 0 |
| Budding and maturation of HIV virion | R-HSA-162588 | 8.582641e-02 | 1.066 | 0 | 0 |
| Nonsense-Mediated Decay (NMD) | R-HSA-927802 | 8.614136e-02 | 1.065 | 0 | 0 |
| Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | R-HSA-975957 | 8.614136e-02 | 1.065 | 0 | 0 |
| Signaling by ERBB2 ECD mutants | R-HSA-9665348 | 8.710207e-02 | 1.060 | 0 | 0 |
| ZBP1(DAI) mediated induction of type I IFNs | R-HSA-1606322 | 8.710207e-02 | 1.060 | 0 | 0 |
| Regulation of PTEN gene transcription | R-HSA-8943724 | 9.027714e-02 | 1.044 | 0 | 0 |
| Signaling by cytosolic PDGFRA and PDGFRB fusion proteins | R-HSA-9673766 | 9.213604e-02 | 1.036 | 0 | 0 |
| MET activates PTPN11 | R-HSA-8865999 | 9.213604e-02 | 1.036 | 0 | 0 |
| SARS-CoV-2 Infection | R-HSA-9694516 | 9.235382e-02 | 1.035 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in pigmentation | R-HSA-9824585 | 9.444243e-02 | 1.025 | 0 | 0 |
| Neutrophil degranulation | R-HSA-6798695 | 9.501749e-02 | 1.022 | 0 | 0 |
| Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | R-HSA-975956 | 9.530467e-02 | 1.021 | 0 | 0 |
| Defective SFTPA2 causes IPF | R-HSA-5687868 | 9.632782e-02 | 1.016 | 0 | 0 |
| APC truncation mutants are not K63 polyubiquitinated | R-HSA-5467333 | 9.632782e-02 | 1.016 | 0 | 0 |
| APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | 9.635160e-02 | 1.016 | 0 | 0 |
| Formation of Senescence-Associated Heterochromatin Foci (SAHF) | R-HSA-2559584 | 9.638289e-02 | 1.016 | 0 | 0 |
| ATF6 (ATF6-alpha) activates chaperones | R-HSA-381033 | 9.638289e-02 | 1.016 | 0 | 0 |
| RNA Polymerase II Transcription Termination | R-HSA-73856 | 9.726367e-02 | 1.012 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Cyclin B | R-HSA-174048 | 9.962745e-02 | 1.002 | 0 | 0 |
| Rap1 signalling | R-HSA-392517 | 9.962745e-02 | 1.002 | 0 | 0 |
| Mechanical load activates signaling by PIEZO1 and integrins in osteocytes | R-HSA-9856532 | 9.962745e-02 | 1.002 | 0 | 0 |
| RAF/MAP kinase cascade | R-HSA-5673001 | 9.969515e-02 | 1.001 | 0 | 0 |
| Regulation of TP53 Activity | R-HSA-5633007 | 1.011578e-01 | 0.995 | 0 | 0 |
| CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde | R-HSA-442729 | 1.023861e-01 | 0.990 | 0 | 0 |
| Type I hemidesmosome assembly | R-HSA-446107 | 1.023861e-01 | 0.990 | 0 | 0 |
| RSK activation | R-HSA-444257 | 1.023861e-01 | 0.990 | 0 | 0 |
| Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation | R-HSA-9828211 | 1.023861e-01 | 0.990 | 0 | 0 |
| Signaling by MRAS-complex mutants | R-HSA-9660537 | 1.023861e-01 | 0.990 | 0 | 0 |
| Gain-of-function MRAS complexes activate RAF signaling | R-HSA-9726842 | 1.023861e-01 | 0.990 | 0 | 0 |
| PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 | R-HSA-8849469 | 1.023861e-01 | 0.990 | 0 | 0 |
| BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members | R-HSA-111453 | 1.023861e-01 | 0.990 | 0 | 0 |
| mRNA Splicing - Minor Pathway | R-HSA-72165 | 1.027098e-01 | 0.988 | 0 | 0 |
| Formation of the ternary complex, and subsequently, the 43S complex | R-HSA-72695 | 1.027098e-01 | 0.988 | 0 | 0 |
| Autodegradation of Cdh1 by Cdh1:APC/C | R-HSA-174084 | 1.027098e-01 | 0.988 | 0 | 0 |
| Integrin signaling | R-HSA-354192 | 1.052906e-01 | 0.978 | 0 | 0 |
| RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known | R-HSA-8939243 | 1.052906e-01 | 0.978 | 0 | 0 |
| SARS-CoV-1-mediated effects on programmed cell death | R-HSA-9692913 | 1.244234e-01 | 0.905 | 0 | 0 |
| Drug-mediated inhibition of CDK4/CDK6 activity | R-HSA-9754119 | 1.244234e-01 | 0.905 | 0 | 0 |
| NFE2L2 regulating ER-stress associated genes | R-HSA-9818035 | 1.244234e-01 | 0.905 | 0 | 0 |
| TGFBR1 KD Mutants in Cancer | R-HSA-3656532 | 1.244234e-01 | 0.905 | 0 | 0 |
| IRF3 mediated activation of type 1 IFN | R-HSA-1606341 | 1.589168e-01 | 0.799 | 0 | 0 |
| IRS activation | R-HSA-74713 | 1.589168e-01 | 0.799 | 0 | 0 |
| Post-transcriptional silencing by small RNAs | R-HSA-426496 | 1.589168e-01 | 0.799 | 0 | 0 |
| NFE2L2 regulating inflammation associated genes | R-HSA-9818026 | 1.589168e-01 | 0.799 | 0 | 0 |
| Signaling by membrane-tethered fusions of PDGFRA or PDGFRB | R-HSA-9673768 | 1.589168e-01 | 0.799 | 0 | 0 |
| SMAD2/3 Phosphorylation Motif Mutants in Cancer | R-HSA-3304356 | 1.589168e-01 | 0.799 | 0 | 0 |
| Activation of RAC1 downstream of NMDARs | R-HSA-9619229 | 1.238111e-01 | 0.907 | 0 | 0 |
| Inactivation of CDC42 and RAC1 | R-HSA-428543 | 1.238111e-01 | 0.907 | 0 | 0 |
| Calcineurin activates NFAT | R-HSA-2025928 | 1.238111e-01 | 0.907 | 0 | 0 |
| MECP2 regulates transcription of neuronal ligands | R-HSA-9022702 | 1.466889e-01 | 0.834 | 0 | 0 |
| Erythropoietin activates Phospholipase C gamma (PLCG) | R-HSA-9027277 | 1.466889e-01 | 0.834 | 0 | 0 |
| Formation of the canonical BAF (cBAF) complex | R-HSA-9933937 | 1.123472e-01 | 0.949 | 0 | 0 |
| Removal of the Flap Intermediate | R-HSA-69166 | 1.123472e-01 | 0.949 | 0 | 0 |
| DCC mediated attractive signaling | R-HSA-418885 | 1.293930e-01 | 0.888 | 0 | 0 |
| Erythropoietin activates RAS | R-HSA-9027284 | 1.293930e-01 | 0.888 | 0 | 0 |
| Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants | R-HSA-1236382 | 1.271864e-01 | 0.896 | 0 | 0 |
| Signaling by Ligand-Responsive EGFR Variants in Cancer | R-HSA-5637815 | 1.271864e-01 | 0.896 | 0 | 0 |
| Lagging Strand Synthesis | R-HSA-69186 | 1.271864e-01 | 0.896 | 0 | 0 |
| APC-Cdc20 mediated degradation of Nek2A | R-HSA-179409 | 1.271864e-01 | 0.896 | 0 | 0 |
| Tat-mediated HIV elongation arrest and recovery | R-HSA-167243 | 1.220722e-01 | 0.913 | 0 | 0 |
| Pausing and recovery of Tat-mediated HIV elongation | R-HSA-167238 | 1.220722e-01 | 0.913 | 0 | 0 |
| HIV elongation arrest and recovery | R-HSA-167287 | 1.348246e-01 | 0.870 | 0 | 0 |
| Pausing and recovery of HIV elongation | R-HSA-167290 | 1.348246e-01 | 0.870 | 0 | 0 |
| Signaling by Erythropoietin | R-HSA-9006335 | 1.481765e-01 | 0.829 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of Securin | R-HSA-174154 | 1.113758e-01 | 0.953 | 0 | 0 |
| Cellular response to starvation | R-HSA-9711097 | 1.341393e-01 | 0.872 | 0 | 0 |
| Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide | R-HSA-9954709 | 1.267395e-01 | 0.897 | 0 | 0 |
| EGFR Transactivation by Gastrin | R-HSA-2179392 | 1.466889e-01 | 0.834 | 0 | 0 |
| RET signaling | R-HSA-8853659 | 1.505984e-01 | 0.822 | 0 | 0 |
| NOTCH4 Activation and Transmission of Signal to the Nucleus | R-HSA-9013700 | 1.238111e-01 | 0.907 | 0 | 0 |
| Unwinding of DNA | R-HSA-176974 | 1.238111e-01 | 0.907 | 0 | 0 |
| Developmental Cell Lineages of the Integumentary System | R-HSA-9734779 | 1.090602e-01 | 0.962 | 0 | 0 |
| Signal attenuation | R-HSA-74749 | 1.466889e-01 | 0.834 | 0 | 0 |
| Pyrophosphate hydrolysis | R-HSA-71737 | 1.589168e-01 | 0.799 | 0 | 0 |
| GP1b-IX-V activation signalling | R-HSA-430116 | 1.238111e-01 | 0.907 | 0 | 0 |
| Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA | R-HSA-450385 | 1.293930e-01 | 0.888 | 0 | 0 |
| Regulation of CDH11 Expression and Function | R-HSA-9759475 | 1.481765e-01 | 0.829 | 0 | 0 |
| PTEN Regulation | R-HSA-6807070 | 1.198709e-01 | 0.921 | 0 | 0 |
| Signaling by FLT3 fusion proteins | R-HSA-9703465 | 1.099466e-01 | 0.959 | 0 | 0 |
| Protein-protein interactions at synapses | R-HSA-6794362 | 1.562312e-01 | 0.806 | 0 | 0 |
| Dopamine Neurotransmitter Release Cycle | R-HSA-212676 | 1.578121e-01 | 0.802 | 0 | 0 |
| Dopamine receptors | R-HSA-390651 | 1.244234e-01 | 0.905 | 0 | 0 |
| AKT-mediated inactivation of FOXO1A | R-HSA-211163 | 1.244234e-01 | 0.905 | 0 | 0 |
| Caspase-mediated cleavage of cytoskeletal proteins | R-HSA-264870 | 1.238111e-01 | 0.907 | 0 | 0 |
| Zinc influx into cells by the SLC39 gene family | R-HSA-442380 | 1.238111e-01 | 0.907 | 0 | 0 |
| Regulation of KIT signaling | R-HSA-1433559 | 1.123472e-01 | 0.949 | 0 | 0 |
| MAPK1/MAPK3 signaling | R-HSA-5684996 | 1.247562e-01 | 0.904 | 0 | 0 |
| Co-stimulation by CD28 | R-HSA-389356 | 1.204350e-01 | 0.919 | 0 | 0 |
| FOXO-mediated transcription of cell cycle genes | R-HSA-9617828 | 1.421393e-01 | 0.847 | 0 | 0 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 1.067208e-01 | 0.972 | 0 | 0 |
| G1/S Transition | R-HSA-69206 | 1.266181e-01 | 0.898 | 0 | 0 |
| TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | R-HSA-6804115 | 1.578121e-01 | 0.802 | 0 | 0 |
| Signaling by PDGFR in disease | R-HSA-9671555 | 1.421393e-01 | 0.847 | 0 | 0 |
| Hemostasis | R-HSA-109582 | 1.542270e-01 | 0.812 | 0 | 0 |
| Zinc transporters | R-HSA-435354 | 1.123472e-01 | 0.949 | 0 | 0 |
| Sensory processing of sound | R-HSA-9659379 | 1.103781e-01 | 0.957 | 0 | 0 |
| NOTCH4 Intracellular Domain Regulates Transcription | R-HSA-9013695 | 1.271864e-01 | 0.896 | 0 | 0 |
| Signaling by Hedgehog | R-HSA-5358351 | 1.145744e-01 | 0.941 | 0 | 0 |
| Regulation of TP53 Degradation | R-HSA-6804757 | 1.505984e-01 | 0.822 | 0 | 0 |
| Eukaryotic Translation Elongation | R-HSA-156842 | 1.601770e-01 | 0.795 | 0 | 0 |
| Cdc20:Phospho-APC/C mediated degradation of Cyclin A | R-HSA-174184 | 1.604478e-01 | 0.795 | 0 | 0 |
| Neurexins and neuroligins | R-HSA-6794361 | 1.604478e-01 | 0.795 | 0 | 0 |
| SARS-CoV-1 activates/modulates innate immune responses | R-HSA-9692916 | 1.604478e-01 | 0.795 | 0 | 0 |
| Signaling by ERBB2 in Cancer | R-HSA-1227990 | 1.620973e-01 | 0.790 | 0 | 0 |
| Activation of the pre-replicative complex | R-HSA-68962 | 1.620973e-01 | 0.790 | 0 | 0 |
| Interleukin-37 signaling | R-HSA-9008059 | 1.620973e-01 | 0.790 | 0 | 0 |
| Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) | R-HSA-936964 | 1.663798e-01 | 0.779 | 0 | 0 |
| Processing of Intronless Pre-mRNAs | R-HSA-77595 | 1.663798e-01 | 0.779 | 0 | 0 |
| Antigen processing: Ub, ATP-independent proteasomal degradation | R-HSA-9912633 | 1.663798e-01 | 0.779 | 0 | 0 |
| Mitotic G1 phase and G1/S transition | R-HSA-453279 | 1.674368e-01 | 0.776 | 0 | 0 |
| NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 | R-HSA-933543 | 1.708063e-01 | 0.767 | 0 | 0 |
| RHOBTB3 ATPase cycle | R-HSA-9706019 | 1.708063e-01 | 0.767 | 0 | 0 |
| ChREBP activates metabolic gene expression | R-HSA-163765 | 1.708063e-01 | 0.767 | 0 | 0 |
| APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | R-HSA-179419 | 1.713437e-01 | 0.766 | 0 | 0 |
| Adipogenesis | R-HSA-9843745 | 1.717892e-01 | 0.765 | 0 | 0 |
| Evasion by RSV of host interferon responses | R-HSA-9833109 | 1.765537e-01 | 0.753 | 0 | 0 |
| CDK-mediated phosphorylation and removal of Cdc6 | R-HSA-69017 | 1.825720e-01 | 0.739 | 0 | 0 |
| Drug-mediated inhibition of MET activation | R-HSA-9734091 | 1.833817e-01 | 0.737 | 0 | 0 |
| Regulation of PAK-2p34 activity by PS-GAP/RHG10 | R-HSA-211728 | 1.833817e-01 | 0.737 | 0 | 0 |
| TICAM1 deficiency - HSE | R-HSA-5602566 | 1.833817e-01 | 0.737 | 0 | 0 |
| Defective Mismatch Repair Associated With PMS2 | R-HSA-5632987 | 1.833817e-01 | 0.737 | 0 | 0 |
| Defective Mismatch Repair Associated With MLH1 | R-HSA-5545483 | 1.833817e-01 | 0.737 | 0 | 0 |
| Formation of editosomes by ADAR proteins | R-HSA-77042 | 1.833817e-01 | 0.737 | 0 | 0 |
| Inhibition of PKR | R-HSA-169131 | 1.833817e-01 | 0.737 | 0 | 0 |
| Infectious disease | R-HSA-5663205 | 1.856966e-01 | 0.731 | 0 | 0 |
| p130Cas linkage to MAPK signaling for integrins | R-HSA-372708 | 1.861320e-01 | 0.730 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | R-HSA-5358565 | 1.861320e-01 | 0.730 | 0 | 0 |
| Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | R-HSA-5358606 | 1.861320e-01 | 0.730 | 0 | 0 |
| Modulation of host responses by IFN-stimulated genes | R-HSA-9909505 | 1.861320e-01 | 0.730 | 0 | 0 |
| Specification of primordial germ cells | R-HSA-9827857 | 1.861320e-01 | 0.730 | 0 | 0 |
| Signaling by FGFR2 | R-HSA-5654738 | 1.881004e-01 | 0.726 | 0 | 0 |
| Expression of BMAL (ARNTL), CLOCK, and NPAS2 | R-HSA-9931509 | 1.896034e-01 | 0.722 | 0 | 0 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | R-HSA-167200 | 1.896034e-01 | 0.722 | 0 | 0 |
| Regulation of TP53 Expression and Degradation | R-HSA-6806003 | 1.896034e-01 | 0.722 | 0 | 0 |
| CD209 (DC-SIGN) signaling | R-HSA-5621575 | 1.911052e-01 | 0.719 | 0 | 0 |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | R-HSA-2173795 | 1.915101e-01 | 0.718 | 0 | 0 |
| Peptide chain elongation | R-HSA-156902 | 1.915245e-01 | 0.718 | 0 | 0 |
| RNA Polymerase II Transcription | R-HSA-73857 | 1.923591e-01 | 0.716 | 0 | 0 |
| Cyclin A:Cdk2-associated events at S phase entry | R-HSA-69656 | 1.939702e-01 | 0.712 | 0 | 0 |
| APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | 1.941181e-01 | 0.712 | 0 | 0 |
| Noncanonical activation of NOTCH3 | R-HSA-9017802 | 1.948922e-01 | 0.710 | 0 | 0 |
| Cam-PDE 1 activation | R-HSA-111957 | 1.948922e-01 | 0.710 | 0 | 0 |
| CDC6 association with the ORC:origin complex | R-HSA-68689 | 1.948922e-01 | 0.710 | 0 | 0 |
| Loss of Function of SMAD2/3 in Cancer | R-HSA-3304349 | 1.948922e-01 | 0.710 | 0 | 0 |
| Defective CSF2RA causes SMDP4 | R-HSA-5688890 | 1.948922e-01 | 0.710 | 0 | 0 |
| Defective CSF2RB causes SMDP5 | R-HSA-5688849 | 1.948922e-01 | 0.710 | 0 | 0 |
| RUNX3 regulates CDKN1A transcription | R-HSA-8941855 | 1.948922e-01 | 0.710 | 0 | 0 |
| SLC15A4:TASL-dependent IRF5 activation | R-HSA-9860276 | 1.948922e-01 | 0.710 | 0 | 0 |
| Aryl hydrocarbon receptor signalling | R-HSA-8937144 | 1.948922e-01 | 0.710 | 0 | 0 |
| RUNX1 regulates expression of components of tight junctions | R-HSA-8935964 | 1.948922e-01 | 0.710 | 0 | 0 |
| Sodium-coupled phosphate cotransporters | R-HSA-427652 | 1.948922e-01 | 0.710 | 0 | 0 |
| Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 | R-HSA-9824878 | 1.959521e-01 | 0.708 | 0 | 0 |
| Activation of RAC1 | R-HSA-428540 | 1.959521e-01 | 0.708 | 0 | 0 |
| Inositol phosphate metabolism | R-HSA-1483249 | 1.980361e-01 | 0.703 | 0 | 0 |
| PIP3 activates AKT signaling | R-HSA-1257604 | 2.028769e-01 | 0.693 | 0 | 0 |
| Transcriptional regulation of white adipocyte differentiation | R-HSA-381340 | 2.032453e-01 | 0.692 | 0 | 0 |
| HIV Transcription Elongation | R-HSA-167169 | 2.034385e-01 | 0.692 | 0 | 0 |
| Tat-mediated elongation of the HIV-1 transcript | R-HSA-167246 | 2.034385e-01 | 0.692 | 0 | 0 |
| Formation of HIV elongation complex in the absence of HIV Tat | R-HSA-167152 | 2.034385e-01 | 0.692 | 0 | 0 |
| Transmission across Chemical Synapses | R-HSA-112315 | 2.044765e-01 | 0.689 | 0 | 0 |
| RSV-host interactions | R-HSA-9833110 | 2.050587e-01 | 0.688 | 0 | 0 |
| Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176814 | 2.059667e-01 | 0.686 | 0 | 0 |
| GAB1 signalosome | R-HSA-180292 | 2.065922e-01 | 0.685 | 0 | 0 |
| Signaling by cytosolic FGFR1 fusion mutants | R-HSA-1839117 | 2.065922e-01 | 0.685 | 0 | 0 |
| Mismatch Repair | R-HSA-5358508 | 2.065922e-01 | 0.685 | 0 | 0 |
| Serotonin Neurotransmitter Release Cycle | R-HSA-181429 | 2.065922e-01 | 0.685 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition | R-HSA-9926550 | 2.065922e-01 | 0.685 | 0 | 0 |
| Regulation of Expression and Function of Type II Classical Cadherins | R-HSA-9764260 | 2.069286e-01 | 0.684 | 0 | 0 |
| Activation of ATR in response to replication stress | R-HSA-176187 | 2.069286e-01 | 0.684 | 0 | 0 |
| Regulation of expression of SLITs and ROBOs | R-HSA-9010553 | 2.088578e-01 | 0.680 | 0 | 0 |
| rRNA processing in the nucleus and cytosol | R-HSA-8868773 | 2.143132e-01 | 0.669 | 0 | 0 |
| Major pathway of rRNA processing in the nucleolus and cytosol | R-HSA-6791226 | 2.154694e-01 | 0.667 | 0 | 0 |
| Beta-catenin independent WNT signaling | R-HSA-3858494 | 2.163543e-01 | 0.665 | 0 | 0 |
| M-decay: degradation of maternal mRNAs by maternally stored factors | R-HSA-9820841 | 2.176454e-01 | 0.662 | 0 | 0 |
| PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA | R-HSA-9954714 | 2.202139e-01 | 0.657 | 0 | 0 |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | R-HSA-9027276 | 2.219211e-01 | 0.654 | 0 | 0 |
| Polymerase switching | R-HSA-69091 | 2.219211e-01 | 0.654 | 0 | 0 |
| Leading Strand Synthesis | R-HSA-69109 | 2.219211e-01 | 0.654 | 0 | 0 |
| Repression of WNT target genes | R-HSA-4641265 | 2.219211e-01 | 0.654 | 0 | 0 |
| Downregulation of ERBB2:ERBB3 signaling | R-HSA-1358803 | 2.219211e-01 | 0.654 | 0 | 0 |
| OAS antiviral response | R-HSA-8983711 | 2.219211e-01 | 0.654 | 0 | 0 |
| Signaling by EGFR in Cancer | R-HSA-1643713 | 2.266145e-01 | 0.645 | 0 | 0 |
| Metalloprotease DUBs | R-HSA-5689901 | 2.266145e-01 | 0.645 | 0 | 0 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | R-HSA-167242 | 2.276604e-01 | 0.643 | 0 | 0 |
| Germ layer formation at gastrulation | R-HSA-9754189 | 2.276604e-01 | 0.643 | 0 | 0 |
| ARL13B-mediated ciliary trafficking of INPP5E | R-HSA-5624958 | 2.620541e-01 | 0.582 | 0 | 0 |
| Signaling by TCF7L2 mutants | R-HSA-5339700 | 2.620541e-01 | 0.582 | 0 | 0 |
| TRAF3 deficiency - HSE | R-HSA-5602571 | 2.620541e-01 | 0.582 | 0 | 0 |
| Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA) | R-HSA-5619054 | 2.620541e-01 | 0.582 | 0 | 0 |
| IKBKB deficiency causes SCID | R-HSA-5602636 | 2.620541e-01 | 0.582 | 0 | 0 |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | R-HSA-5603027 | 2.620541e-01 | 0.582 | 0 | 0 |
| Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) | R-HSA-5619111 | 2.620541e-01 | 0.582 | 0 | 0 |
| Defective GFPT1 causes CMSTA1 | R-HSA-4085023 | 2.620541e-01 | 0.582 | 0 | 0 |
| SMAD2/3 MH2 Domain Mutants in Cancer | R-HSA-3315487 | 2.620541e-01 | 0.582 | 0 | 0 |
| Loss of Function of SMAD4 in Cancer | R-HSA-3304347 | 2.620541e-01 | 0.582 | 0 | 0 |
| SMAD4 MH2 Domain Mutants in Cancer | R-HSA-3311021 | 2.620541e-01 | 0.582 | 0 | 0 |
| Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) | R-HSA-5619039 | 2.620541e-01 | 0.582 | 0 | 0 |
| Stimulation of the cell death response by PAK-2p34 | R-HSA-211736 | 3.331514e-01 | 0.477 | 0 | 0 |
| TWIK related potassium channel (TREK) | R-HSA-1299503 | 3.331514e-01 | 0.477 | 0 | 0 |
| TGFBR1 LBD Mutants in Cancer | R-HSA-3656535 | 3.331514e-01 | 0.477 | 0 | 0 |
| Defective ABCB6 causes MCOPCB7 | R-HSA-5683371 | 3.331514e-01 | 0.477 | 0 | 0 |
| Small interfering RNA (siRNA) biogenesis | R-HSA-426486 | 2.317445e-01 | 0.635 | 0 | 0 |
| Erythropoietin activates STAT5 | R-HSA-9027283 | 2.317445e-01 | 0.635 | 0 | 0 |
| RUNX3 regulates YAP1-mediated transcription | R-HSA-8951671 | 2.317445e-01 | 0.635 | 0 | 0 |
| E2F-enabled inhibition of pre-replication complex formation | R-HSA-113507 | 2.317445e-01 | 0.635 | 0 | 0 |
| MECP2 regulates transcription factors | R-HSA-9022707 | 2.689714e-01 | 0.570 | 0 | 0 |
| MET activates PI3K/AKT signaling | R-HSA-8851907 | 2.689714e-01 | 0.570 | 0 | 0 |
| Role of ABL in ROBO-SLIT signaling | R-HSA-428890 | 2.689714e-01 | 0.570 | 0 | 0 |
| NOSTRIN mediated eNOS trafficking | R-HSA-203641 | 2.689714e-01 | 0.570 | 0 | 0 |
| Disinhibition of SNARE formation | R-HSA-114516 | 2.689714e-01 | 0.570 | 0 | 0 |
| MET interacts with TNS proteins | R-HSA-8875513 | 3.974026e-01 | 0.401 | 0 | 0 |
| Negative regulation of TCF-dependent signaling by DVL-interacting proteins | R-HSA-5368598 | 3.974026e-01 | 0.401 | 0 | 0 |
| Axonal growth stimulation | R-HSA-209563 | 3.974026e-01 | 0.401 | 0 | 0 |
| Defective SLC7A7 causes lysinuric protein intolerance (LPI) | R-HSA-5660862 | 3.974026e-01 | 0.401 | 0 | 0 |
| Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome | R-HSA-9944997 | 3.974026e-01 | 0.401 | 0 | 0 |
| Defective ABCC2 causes DJS | R-HSA-5679001 | 3.974026e-01 | 0.401 | 0 | 0 |
| Invadopodia formation | R-HSA-8941237 | 3.974026e-01 | 0.401 | 0 | 0 |
| Loss of Function of KMT2D in Kabuki Syndrome | R-HSA-9944971 | 3.974026e-01 | 0.401 | 0 | 0 |
| MET receptor recycling | R-HSA-8875656 | 3.061591e-01 | 0.514 | 0 | 0 |
| Regulation of NPAS4 mRNA translation | R-HSA-9768778 | 3.061591e-01 | 0.514 | 0 | 0 |
| Formation of the non-canonical BAF (ncBAF) complex | R-HSA-9933947 | 2.485174e-01 | 0.605 | 0 | 0 |
| Lipophagy | R-HSA-9613354 | 3.429697e-01 | 0.465 | 0 | 0 |
| WNT mediated activation of DVL | R-HSA-201688 | 3.429697e-01 | 0.465 | 0 | 0 |
| AKT phosphorylates targets in the nucleus | R-HSA-198693 | 3.429697e-01 | 0.465 | 0 | 0 |
| RUNX3 regulates BCL2L11 (BIM) transcription | R-HSA-8952158 | 4.554667e-01 | 0.342 | 0 | 0 |
| PLCG1 events in ERBB2 signaling | R-HSA-1251932 | 4.554667e-01 | 0.342 | 0 | 0 |
| Inhibition of TSC complex formation by PKB | R-HSA-165181 | 4.554667e-01 | 0.342 | 0 | 0 |
| Transcription of E2F targets under negative control by DREAM complex | R-HSA-1362277 | 2.492368e-01 | 0.603 | 0 | 0 |
| Co-inhibition by CTLA4 | R-HSA-389513 | 2.492368e-01 | 0.603 | 0 | 0 |
| IRF3-mediated induction of type I IFN | R-HSA-3270619 | 3.028652e-01 | 0.519 | 0 | 0 |
| TICAM1, RIP1-mediated IKK complex recruitment | R-HSA-168927 | 3.028652e-01 | 0.519 | 0 | 0 |
| TNFR1-induced proapoptotic signaling | R-HSA-5357786 | 2.712234e-01 | 0.567 | 0 | 0 |
| TICAM1,TRAF6-dependent induction of TAK1 complex | R-HSA-9014325 | 3.791311e-01 | 0.421 | 0 | 0 |
| Folding of actin by CCT/TriC | R-HSA-390450 | 3.791311e-01 | 0.421 | 0 | 0 |
| Dual Incision in GG-NER | R-HSA-5696400 | 2.389935e-01 | 0.622 | 0 | 0 |
| G beta:gamma signalling through CDC42 | R-HSA-8964616 | 3.576750e-01 | 0.447 | 0 | 0 |
| Regulation of CDH11 mRNA translation by microRNAs | R-HSA-9759811 | 4.144267e-01 | 0.383 | 0 | 0 |
| Signaling by APC mutants | R-HSA-4839744 | 4.144267e-01 | 0.383 | 0 | 0 |
| AXIN missense mutants destabilize the destruction complex | R-HSA-5467340 | 4.144267e-01 | 0.383 | 0 | 0 |
| Truncations of AMER1 destabilize the destruction complex | R-HSA-5467348 | 4.144267e-01 | 0.383 | 0 | 0 |
| APC truncation mutants have impaired AXIN binding | R-HSA-5467337 | 4.144267e-01 | 0.383 | 0 | 0 |
| RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression | R-HSA-9933387 | 3.023564e-01 | 0.519 | 0 | 0 |
| SHC1 events in ERBB2 signaling | R-HSA-1250196 | 3.023564e-01 | 0.519 | 0 | 0 |
| Regulation of RAS by GAPs | R-HSA-5658442 | 2.386640e-01 | 0.622 | 0 | 0 |
| Removal of the Flap Intermediate from the C-strand | R-HSA-174437 | 3.849010e-01 | 0.415 | 0 | 0 |
| Regulation of activated PAK-2p34 by proteasome mediated degradation | R-HSA-211733 | 3.219237e-01 | 0.492 | 0 | 0 |
| Orc1 removal from chromatin | R-HSA-68949 | 2.664651e-01 | 0.574 | 0 | 0 |
| MET promotes cell motility | R-HSA-8875878 | 3.068752e-01 | 0.513 | 0 | 0 |
| Signaling by ERBB2 TMD/JMD mutants | R-HSA-9665686 | 3.614154e-01 | 0.442 | 0 | 0 |
| Processing of Capped Intronless Pre-mRNA | R-HSA-75067 | 3.614154e-01 | 0.442 | 0 | 0 |
| Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 3.614154e-01 | 0.442 | 0 | 0 |
| Sema4D mediated inhibition of cell attachment and migration | R-HSA-416550 | 4.486878e-01 | 0.348 | 0 | 0 |
| APOBEC3G mediated resistance to HIV-1 infection | R-HSA-180689 | 4.486878e-01 | 0.348 | 0 | 0 |
| Signaling by GSK3beta mutants | R-HSA-5339716 | 4.486878e-01 | 0.348 | 0 | 0 |
| Transcription of the HIV genome | R-HSA-167172 | 2.462799e-01 | 0.609 | 0 | 0 |
| PCNA-Dependent Long Patch Base Excision Repair | R-HSA-5651801 | 4.118483e-01 | 0.385 | 0 | 0 |
| PKA activation | R-HSA-163615 | 4.118483e-01 | 0.385 | 0 | 0 |
| Association of TriC/CCT with target proteins during biosynthesis | R-HSA-390471 | 3.812199e-01 | 0.419 | 0 | 0 |
| Regulation of signaling by CBL | R-HSA-912631 | 4.384141e-01 | 0.358 | 0 | 0 |
| IKK complex recruitment mediated by RIP1 | R-HSA-937041 | 4.384141e-01 | 0.358 | 0 | 0 |
| Ubiquitin-dependent degradation of Cyclin D | R-HSA-75815 | 4.010059e-01 | 0.397 | 0 | 0 |
| Processive synthesis on the C-strand of the telomere | R-HSA-174414 | 4.290915e-01 | 0.367 | 0 | 0 |
| RNA Polymerase I Transcription Termination | R-HSA-73863 | 4.290915e-01 | 0.367 | 0 | 0 |
| Developmental Lineage of Mammary Gland Luminal Epithelial Cells | R-HSA-9927418 | 3.953331e-01 | 0.403 | 0 | 0 |
| Formation of the HIV-1 Early Elongation Complex | R-HSA-167158 | 4.512745e-01 | 0.346 | 0 | 0 |
| Formation of the Early Elongation Complex | R-HSA-113418 | 4.512745e-01 | 0.346 | 0 | 0 |
| Developmental Lineage of Pancreatic Ductal Cells | R-HSA-9925563 | 3.793497e-01 | 0.421 | 0 | 0 |
| ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA | R-HSA-9954716 | 3.771042e-01 | 0.424 | 0 | 0 |
| Post-translational protein phosphorylation | R-HSA-8957275 | 4.255380e-01 | 0.371 | 0 | 0 |
| SRP-dependent cotranslational protein targeting to membrane | R-HSA-1799339 | 4.301147e-01 | 0.366 | 0 | 0 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 3.614099e-01 | 0.442 | 0 | 0 |
| G-protein beta:gamma signalling | R-HSA-397795 | 3.614099e-01 | 0.442 | 0 | 0 |
| Negative regulators of DDX58/IFIH1 signaling | R-HSA-936440 | 3.219237e-01 | 0.492 | 0 | 0 |
| UCH proteinases | R-HSA-5689603 | 3.478952e-01 | 0.459 | 0 | 0 |
| Ribosome-associated quality control | R-HSA-9948299 | 3.122853e-01 | 0.505 | 0 | 0 |
| Global Genome Nucleotide Excision Repair (GG-NER) | R-HSA-5696399 | 4.545669e-01 | 0.342 | 0 | 0 |
| EPH-ephrin mediated repulsion of cells | R-HSA-3928665 | 3.249900e-01 | 0.488 | 0 | 0 |
| Signaling by ERBB2 KD Mutants | R-HSA-9664565 | 2.829823e-01 | 0.548 | 0 | 0 |
| Metabolism of nitric oxide: NOS3 activation and regulation | R-HSA-202131 | 3.068752e-01 | 0.513 | 0 | 0 |
| Synthesis of active ubiquitin: roles of E1 and E2 enzymes | R-HSA-8866652 | 4.290915e-01 | 0.367 | 0 | 0 |
| eNOS activation | R-HSA-203615 | 4.010059e-01 | 0.397 | 0 | 0 |
| Apoptosis induced DNA fragmentation | R-HSA-140342 | 3.791311e-01 | 0.421 | 0 | 0 |
| Degradation of beta-catenin by the destruction complex | R-HSA-195253 | 3.935001e-01 | 0.405 | 0 | 0 |
| Platelet Aggregation (Plug Formation) | R-HSA-76009 | 2.932189e-01 | 0.533 | 0 | 0 |
| MET Receptor Activation | R-HSA-6806942 | 2.317445e-01 | 0.635 | 0 | 0 |
| Regulation of CDH11 function | R-HSA-9762292 | 3.791311e-01 | 0.421 | 0 | 0 |
| PI3K/AKT activation | R-HSA-198203 | 3.791311e-01 | 0.421 | 0 | 0 |
| POLB-Dependent Long Patch Base Excision Repair | R-HSA-110362 | 4.486878e-01 | 0.348 | 0 | 0 |
| DNA Damage Recognition in GG-NER | R-HSA-5696394 | 3.812199e-01 | 0.419 | 0 | 0 |
| Eukaryotic Translation Termination | R-HSA-72764 | 2.823732e-01 | 0.549 | 0 | 0 |
| Regulation of Apoptosis | R-HSA-169911 | 4.207195e-01 | 0.376 | 0 | 0 |
| Sensing of DNA Double Strand Breaks | R-HSA-5693548 | 4.486878e-01 | 0.348 | 0 | 0 |
| Antigen processing: Ubiquitination & Proteasome degradation | R-HSA-983168 | 2.903204e-01 | 0.537 | 0 | 0 |
| Nef mediated downregulation of MHC class I complex cell surface expression | R-HSA-164940 | 3.061591e-01 | 0.514 | 0 | 0 |
| Formation of axial mesoderm | R-HSA-9796292 | 2.485174e-01 | 0.605 | 0 | 0 |
| Regulation of gap junction activity | R-HSA-191650 | 4.554667e-01 | 0.342 | 0 | 0 |
| RIP-mediated NFkB activation via ZBP1 | R-HSA-1810476 | 3.028652e-01 | 0.519 | 0 | 0 |
| G beta:gamma signalling through PI3Kgamma | R-HSA-392451 | 3.387063e-01 | 0.470 | 0 | 0 |
| Trafficking of AMPA receptors | R-HSA-399719 | 3.219237e-01 | 0.492 | 0 | 0 |
| Regulation of mitotic cell cycle | R-HSA-453276 | 2.832631e-01 | 0.548 | 0 | 0 |
| APC/C-mediated degradation of cell cycle proteins | R-HSA-174143 | 2.832631e-01 | 0.548 | 0 | 0 |
| PINK1-PRKN Mediated Mitophagy | R-HSA-5205685 | 4.512745e-01 | 0.346 | 0 | 0 |
| Vif-mediated degradation of APOBEC3G | R-HSA-180585 | 4.403154e-01 | 0.356 | 0 | 0 |
| Resolution of AP sites via the multiple-nucleotide patch replacement pathway | R-HSA-110373 | 4.066783e-01 | 0.391 | 0 | 0 |
| Netrin-1 signaling | R-HSA-373752 | 4.308290e-01 | 0.366 | 0 | 0 |
| Integration of provirus | R-HSA-162592 | 4.486878e-01 | 0.348 | 0 | 0 |
| Ca2+ pathway | R-HSA-4086398 | 3.087485e-01 | 0.510 | 0 | 0 |
| Regulation of RUNX1 Expression and Activity | R-HSA-8934593 | 4.066783e-01 | 0.391 | 0 | 0 |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | R-HSA-442720 | 2.485174e-01 | 0.605 | 0 | 0 |
| Nuclear RNA decay | R-HSA-9930044 | 3.614099e-01 | 0.442 | 0 | 0 |
| SPOP-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929491 | 3.597521e-01 | 0.444 | 0 | 0 |
| Fanconi Anemia Pathway | R-HSA-6783310 | 4.484588e-01 | 0.348 | 0 | 0 |
| Proteasome assembly | R-HSA-9907900 | 4.308290e-01 | 0.366 | 0 | 0 |
| Ephrin signaling | R-HSA-3928664 | 4.118483e-01 | 0.385 | 0 | 0 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 3.429697e-01 | 0.465 | 0 | 0 |
| Cellular response to chemical stress | R-HSA-9711123 | 2.608991e-01 | 0.584 | 0 | 0 |
| FasL/ CD95L signaling | R-HSA-75157 | 3.974026e-01 | 0.401 | 0 | 0 |
| Processing of SMDT1 | R-HSA-8949664 | 2.485174e-01 | 0.605 | 0 | 0 |
| WNT5A-dependent internalization of FZD4 | R-HSA-5099900 | 3.302863e-01 | 0.481 | 0 | 0 |
| Complex III assembly | R-HSA-9865881 | 3.614154e-01 | 0.442 | 0 | 0 |
| Polo-like kinase mediated events | R-HSA-156711 | 4.118483e-01 | 0.385 | 0 | 0 |
| Signaling by FGFR1 in disease | R-HSA-5655302 | 3.775353e-01 | 0.423 | 0 | 0 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 3.935001e-01 | 0.405 | 0 | 0 |
| RMTs methylate histone arginines | R-HSA-3214858 | 2.776012e-01 | 0.557 | 0 | 0 |
| Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 4.179214e-01 | 0.379 | 1 | 0 |
| ROBO receptors bind AKAP5 | R-HSA-9010642 | 3.061591e-01 | 0.514 | 0 | 0 |
| Myogenesis | R-HSA-525793 | 4.066783e-01 | 0.391 | 0 | 0 |
| Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 4.068678e-01 | 0.391 | 1 | 0 |
| Cytosolic sensors of pathogen-associated DNA | R-HSA-1834949 | 2.707533e-01 | 0.567 | 0 | 0 |
| CD28 dependent PI3K/Akt signaling | R-HSA-389357 | 2.450508e-01 | 0.611 | 0 | 0 |
| Activation of gene expression by SREBF (SREBP) | R-HSA-2426168 | 4.298239e-01 | 0.367 | 0 | 0 |
| Signaling by PTK6 | R-HSA-8848021 | 4.298239e-01 | 0.367 | 0 | 0 |
| Signaling by Non-Receptor Tyrosine Kinases | R-HSA-9006927 | 4.298239e-01 | 0.367 | 0 | 0 |
| PCP/CE pathway | R-HSA-4086400 | 3.744132e-01 | 0.427 | 0 | 0 |
| NOTCH3 Activation and Transmission of Signal to the Nucleus | R-HSA-9013507 | 3.160482e-01 | 0.500 | 0 | 0 |
| Heme signaling | R-HSA-9707616 | 2.824515e-01 | 0.549 | 0 | 0 |
| Surfactant metabolism | R-HSA-5683826 | 4.308290e-01 | 0.366 | 0 | 0 |
| Synthesis of PIPs at the plasma membrane | R-HSA-1660499 | 4.147203e-01 | 0.382 | 0 | 0 |
| Inhibition of Host mRNA Processing and RNA Silencing | R-HSA-168315 | 2.620541e-01 | 0.582 | 0 | 0 |
| mRNA Editing: A to I Conversion | R-HSA-75064 | 3.331514e-01 | 0.477 | 0 | 0 |
| Interleukin-33 signaling | R-HSA-9014843 | 3.331514e-01 | 0.477 | 0 | 0 |
| Localization of the PINCH-ILK-PARVIN complex to focal adhesions | R-HSA-446343 | 3.331514e-01 | 0.477 | 0 | 0 |
| C6 deamination of adenosine | R-HSA-75102 | 3.331514e-01 | 0.477 | 0 | 0 |
| STAT6-mediated induction of chemokines | R-HSA-3249367 | 3.974026e-01 | 0.401 | 0 | 0 |
| MET activates STAT3 | R-HSA-8875791 | 3.974026e-01 | 0.401 | 0 | 0 |
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 3.061591e-01 | 0.514 | 0 | 0 |
| SARS-CoV-2 targets PDZ proteins in cell-cell junction | R-HSA-9705677 | 4.554667e-01 | 0.342 | 0 | 0 |
| GABA synthesis | R-HSA-888568 | 4.554667e-01 | 0.342 | 0 | 0 |
| VxPx cargo-targeting to cilium | R-HSA-5620916 | 2.492368e-01 | 0.603 | 0 | 0 |
| Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA | R-HSA-450513 | 3.028652e-01 | 0.519 | 0 | 0 |
| Defective RIPK1-mediated regulated necrosis | R-HSA-9693928 | 3.791311e-01 | 0.421 | 0 | 0 |
| Receptor-type tyrosine-protein phosphatases | R-HSA-388844 | 3.302863e-01 | 0.481 | 0 | 0 |
| Phase 0 - rapid depolarisation | R-HSA-5576892 | 2.638603e-01 | 0.579 | 0 | 0 |
| Signaling by AXIN mutants | R-HSA-4839735 | 4.486878e-01 | 0.348 | 0 | 0 |
| Signaling by AMER1 mutants | R-HSA-4839748 | 4.486878e-01 | 0.348 | 0 | 0 |
| Negative regulation of NOTCH4 signaling | R-HSA-9604323 | 3.420214e-01 | 0.466 | 0 | 0 |
| E2F mediated regulation of DNA replication | R-HSA-113510 | 4.384141e-01 | 0.358 | 0 | 0 |
| Signaling by FGFR2 IIIa TM | R-HSA-8851708 | 4.384141e-01 | 0.358 | 0 | 0 |
| Neuronal System | R-HSA-112316 | 2.781907e-01 | 0.556 | 0 | 0 |
| Signaling by FGFR | R-HSA-190236 | 3.153422e-01 | 0.501 | 0 | 0 |
| Regulation of CDH11 gene transcription | R-HSA-9762293 | 3.429697e-01 | 0.465 | 0 | 0 |
| RAB GEFs exchange GTP for GDP on RABs | R-HSA-8876198 | 3.570720e-01 | 0.447 | 0 | 0 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 3.921640e-01 | 0.407 | 0 | 0 |
| STING mediated induction of host immune responses | R-HSA-1834941 | 4.384141e-01 | 0.358 | 0 | 0 |
| Generic Transcription Pathway | R-HSA-212436 | 3.003327e-01 | 0.522 | 0 | 0 |
| VEGFR2 mediated cell proliferation | R-HSA-5218921 | 3.840971e-01 | 0.416 | 0 | 0 |
| Extra-nuclear estrogen signaling | R-HSA-9009391 | 2.509390e-01 | 0.600 | 0 | 0 |
| CHL1 interactions | R-HSA-447041 | 2.689714e-01 | 0.570 | 0 | 0 |
| TNFR1-induced NF-kappa-B signaling pathway | R-HSA-5357956 | 4.290915e-01 | 0.367 | 0 | 0 |
| Cardiac conduction | R-HSA-5576891 | 2.409935e-01 | 0.618 | 0 | 0 |
| Signaling by FGFR in disease | R-HSA-1226099 | 4.501105e-01 | 0.347 | 0 | 0 |
| Signaling by NTRK1 (TRKA) | R-HSA-187037 | 3.789593e-01 | 0.421 | 1 | 0 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 3.597521e-01 | 0.444 | 0 | 0 |
| Regulation of NPAS4 gene expression | R-HSA-9768759 | 3.849010e-01 | 0.415 | 0 | 0 |
| Regulation of APC/C activators between G1/S and early anaphase | R-HSA-176408 | 2.824515e-01 | 0.549 | 0 | 0 |
| Signaling by NOTCH3 | R-HSA-9012852 | 3.097484e-01 | 0.509 | 0 | 0 |
| Inhibition of membrane repair | R-HSA-9635644 | 2.620541e-01 | 0.582 | 0 | 0 |
| DSCAM interactions | R-HSA-376172 | 3.331514e-01 | 0.477 | 0 | 0 |
| Diseases of Mismatch Repair (MMR) | R-HSA-5423599 | 3.974026e-01 | 0.401 | 0 | 0 |
| Cellular response to mitochondrial stress | R-HSA-9840373 | 3.429697e-01 | 0.465 | 0 | 0 |
| NADE modulates death signalling | R-HSA-205025 | 4.554667e-01 | 0.342 | 0 | 0 |
| Activation of SMO | R-HSA-5635838 | 3.302863e-01 | 0.481 | 0 | 0 |
| CD163 mediating an anti-inflammatory response | R-HSA-9662834 | 4.144267e-01 | 0.383 | 0 | 0 |
| Synthesis of IP3 and IP4 in the cytosol | R-HSA-1855204 | 3.614099e-01 | 0.442 | 0 | 0 |
| Glutamate binding, activation of AMPA receptors and synaptic plasticity | R-HSA-399721 | 3.614099e-01 | 0.442 | 0 | 0 |
| Effects of PIP2 hydrolysis | R-HSA-114508 | 3.812199e-01 | 0.419 | 0 | 0 |
| Platelet homeostasis | R-HSA-418346 | 4.184885e-01 | 0.378 | 0 | 0 |
| Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | R-HSA-8864260 | 4.308290e-01 | 0.366 | 0 | 0 |
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | R-HSA-1474151 | 3.023564e-01 | 0.519 | 0 | 0 |
| Regulation of PTEN stability and activity | R-HSA-8948751 | 2.807062e-01 | 0.552 | 0 | 0 |
| Cyclin E associated events during G1/S transition | R-HSA-69202 | 2.707533e-01 | 0.567 | 0 | 0 |
| Ion channel transport | R-HSA-983712 | 2.881201e-01 | 0.540 | 0 | 0 |
| EGR2 and SOX10-mediated initiation of Schwann cell myelination | R-HSA-9619665 | 3.812199e-01 | 0.419 | 0 | 0 |
| FOXO-mediated transcription | R-HSA-9614085 | 2.313612e-01 | 0.636 | 0 | 0 |
| Histamine receptors | R-HSA-390650 | 3.974026e-01 | 0.401 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in differentiation of myeloid cells | R-HSA-8939246 | 3.061591e-01 | 0.514 | 0 | 0 |
| Positive Regulation of CDH1 Gene Transcription | R-HSA-9764790 | 3.791311e-01 | 0.421 | 0 | 0 |
| PECAM1 interactions | R-HSA-210990 | 4.144267e-01 | 0.383 | 0 | 0 |
| Syndecan interactions | R-HSA-3000170 | 3.387063e-01 | 0.470 | 0 | 0 |
| Cyclin A/B1/B2 associated events during G2/M transition | R-HSA-69273 | 3.614099e-01 | 0.442 | 0 | 0 |
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 2.689714e-01 | 0.570 | 0 | 0 |
| The NLRP1 inflammasome | R-HSA-844455 | 3.974026e-01 | 0.401 | 0 | 0 |
| Interleukin-18 signaling | R-HSA-9012546 | 3.061591e-01 | 0.514 | 0 | 0 |
| Regulation of HMOX1 expression and activity | R-HSA-9707587 | 4.554667e-01 | 0.342 | 0 | 0 |
| Assembly and release of respiratory syncytial virus (RSV) virions | R-HSA-9820962 | 3.791311e-01 | 0.421 | 0 | 0 |
| Sodium/Calcium exchangers | R-HSA-425561 | 4.486878e-01 | 0.348 | 0 | 0 |
| G1/S-Specific Transcription | R-HSA-69205 | 2.724211e-01 | 0.565 | 0 | 0 |
| ATF6B (ATF6-beta) activates chaperones | R-HSA-8874177 | 3.331514e-01 | 0.477 | 0 | 0 |
| RUNX3 Regulates Immune Response and Cell Migration | R-HSA-8949275 | 2.689714e-01 | 0.570 | 0 | 0 |
| Signal regulatory protein family interactions | R-HSA-391160 | 2.755561e-01 | 0.560 | 0 | 0 |
| Respiratory syncytial virus genome replication | R-HSA-9834752 | 3.429697e-01 | 0.465 | 0 | 0 |
| Basigin interactions | R-HSA-210991 | 2.712234e-01 | 0.567 | 0 | 0 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 4.144949e-01 | 0.382 | 0 | 0 |
| Insulin processing | R-HSA-264876 | 4.290915e-01 | 0.367 | 0 | 0 |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | R-HSA-8866910 | 3.576750e-01 | 0.447 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9694631 | 4.384141e-01 | 0.358 | 0 | 0 |
| Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 4.384141e-01 | 0.358 | 0 | 0 |
| Signaling by Leptin | R-HSA-2586552 | 3.791311e-01 | 0.421 | 0 | 0 |
| GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 | R-HSA-9762114 | 4.597510e-01 | 0.337 | 0 | 0 |
| TRAF6 mediated IRF7 activation | R-HSA-933541 | 4.597510e-01 | 0.337 | 0 | 0 |
| Degradation of DVL | R-HSA-4641258 | 4.597510e-01 | 0.337 | 0 | 0 |
| Selenocysteine synthesis | R-HSA-2408557 | 4.618660e-01 | 0.335 | 0 | 0 |
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | R-HSA-9609523 | 4.645089e-01 | 0.333 | 0 | 0 |
| Creatine metabolism | R-HSA-71288 | 4.645089e-01 | 0.333 | 0 | 0 |
| Signal transduction by L1 | R-HSA-445144 | 4.645089e-01 | 0.333 | 0 | 0 |
| MyD88-independent TLR4 cascade | R-HSA-166166 | 4.649275e-01 | 0.333 | 1 | 0 |
| TRIF (TICAM1)-mediated TLR4 signaling | R-HSA-937061 | 4.649275e-01 | 0.333 | 1 | 0 |
| PI3K/AKT Signaling in Cancer | R-HSA-2219528 | 4.676943e-01 | 0.330 | 0 | 0 |
| mRNA Capping | R-HSA-72086 | 4.731710e-01 | 0.325 | 0 | 0 |
| Termination of translesion DNA synthesis | R-HSA-5656169 | 4.731710e-01 | 0.325 | 0 | 0 |
| MAPK targets/ Nuclear events mediated by MAP kinases | R-HSA-450282 | 4.731710e-01 | 0.325 | 0 | 0 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 4.789868e-01 | 0.320 | 0 | 0 |
| MET activates RAS signaling | R-HSA-8851805 | 4.817862e-01 | 0.317 | 0 | 0 |
| RUNX3 regulates p14-ARF | R-HSA-8951936 | 4.817862e-01 | 0.317 | 0 | 0 |
| Signaling by CTNNB1 phospho-site mutants | R-HSA-4839743 | 4.817862e-01 | 0.317 | 0 | 0 |
| Z-decay: degradation of maternal mRNAs by zygotically expressed factors | R-HSA-9820865 | 4.817862e-01 | 0.317 | 0 | 0 |
| GRB2 events in EGFR signaling | R-HSA-179812 | 4.817862e-01 | 0.317 | 0 | 0 |
| CTNNB1 S37 mutants aren't phosphorylated | R-HSA-5358749 | 4.817862e-01 | 0.317 | 0 | 0 |
| CTNNB1 T41 mutants aren't phosphorylated | R-HSA-5358752 | 4.817862e-01 | 0.317 | 0 | 0 |
| CTNNB1 S45 mutants aren't phosphorylated | R-HSA-5358751 | 4.817862e-01 | 0.317 | 0 | 0 |
| CTNNB1 S33 mutants aren't phosphorylated | R-HSA-5358747 | 4.817862e-01 | 0.317 | 0 | 0 |
| Phosphorylation and nuclear translocation of the CRY:PER:kinase complex | R-HSA-9931530 | 4.817862e-01 | 0.317 | 0 | 0 |
| Diseases associated with surfactant metabolism | R-HSA-5687613 | 4.817862e-01 | 0.317 | 0 | 0 |
| Signaling by LTK | R-HSA-9842663 | 4.817862e-01 | 0.317 | 0 | 0 |
| Viral mRNA Translation | R-HSA-192823 | 4.859202e-01 | 0.313 | 0 | 0 |
| Early Phase of HIV Life Cycle | R-HSA-162594 | 4.900557e-01 | 0.310 | 0 | 0 |
| G-protein activation | R-HSA-202040 | 4.900557e-01 | 0.310 | 0 | 0 |
| PKA-mediated phosphorylation of CREB | R-HSA-111931 | 4.900557e-01 | 0.310 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in apoptosis | R-HSA-9824594 | 4.900557e-01 | 0.310 | 0 | 0 |
| ERK/MAPK targets | R-HSA-198753 | 4.900557e-01 | 0.310 | 0 | 0 |
| NOTCH3 Intracellular Domain Regulates Transcription | R-HSA-9013508 | 4.947302e-01 | 0.306 | 0 | 0 |
| DDX58/IFIH1-mediated induction of interferon-alpha/beta | R-HSA-168928 | 4.961423e-01 | 0.304 | 0 | 0 |
| Cross-presentation of soluble exogenous antigens (endosomes) | R-HSA-1236978 | 4.979864e-01 | 0.303 | 0 | 0 |
| Respiratory syncytial virus (RSV) genome replication, transcription and translation | R-HSA-9820965 | 4.979864e-01 | 0.303 | 0 | 0 |
| Gluconeogenesis | R-HSA-70263 | 5.005044e-01 | 0.301 | 0 | 0 |
| Metal ion SLC transporters | R-HSA-425410 | 5.005044e-01 | 0.301 | 0 | 0 |
| Dual incision in TC-NER | R-HSA-6782135 | 5.025746e-01 | 0.299 | 0 | 0 |
| NFE2L2 regulating TCA cycle genes | R-HSA-9818025 | 5.079389e-01 | 0.294 | 0 | 0 |
| NOSIP mediated eNOS trafficking | R-HSA-203754 | 5.079389e-01 | 0.294 | 0 | 0 |
| FLT3 signaling by CBL mutants | R-HSA-9706377 | 5.079389e-01 | 0.294 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in interleukin signaling | R-HSA-8939247 | 5.079389e-01 | 0.294 | 0 | 0 |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | R-HSA-3134963 | 5.079389e-01 | 0.294 | 0 | 0 |
| RUNX1 regulates transcription of genes involved in BCR signaling | R-HSA-8939245 | 5.079389e-01 | 0.294 | 0 | 0 |
| PTK6 Regulates Proteins Involved in RNA Processing | R-HSA-8849468 | 5.079389e-01 | 0.294 | 0 | 0 |
| Muscarinic acetylcholine receptors | R-HSA-390648 | 5.079389e-01 | 0.294 | 0 | 0 |
| SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes | R-HSA-111464 | 5.079389e-01 | 0.294 | 0 | 0 |
| Interleukin-36 pathway | R-HSA-9014826 | 5.079389e-01 | 0.294 | 0 | 0 |
| Biosynthesis of DPAn-3-derived 13-series resolvins | R-HSA-9026403 | 5.079389e-01 | 0.294 | 0 | 0 |
| SMAC (DIABLO) binds to IAPs | R-HSA-111463 | 5.079389e-01 | 0.294 | 0 | 0 |
| NrCAM interactions | R-HSA-447038 | 5.079389e-01 | 0.294 | 0 | 0 |
| Zinc efflux and compartmentalization by the SLC30 family | R-HSA-435368 | 5.079389e-01 | 0.294 | 0 | 0 |
| Assembly of Viral Components at the Budding Site | R-HSA-168316 | 5.079389e-01 | 0.294 | 0 | 0 |
| HDR through MMEJ (alt-NHEJ) | R-HSA-5685939 | 5.136279e-01 | 0.289 | 0 | 0 |
| Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) | R-HSA-9661069 | 5.136279e-01 | 0.289 | 0 | 0 |
| Golgi Cisternae Pericentriolar Stack Reorganization | R-HSA-162658 | 5.136279e-01 | 0.289 | 0 | 0 |
| Frs2-mediated activation | R-HSA-170968 | 5.136279e-01 | 0.289 | 0 | 0 |
| Membrane binding and targetting of GAG proteins | R-HSA-174490 | 5.136279e-01 | 0.289 | 0 | 0 |
| Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects | R-HSA-9659787 | 5.136279e-01 | 0.289 | 0 | 0 |
| CD28 dependent Vav1 pathway | R-HSA-389359 | 5.136279e-01 | 0.289 | 0 | 0 |
| Maturation of nucleoprotein | R-HSA-9683610 | 5.136279e-01 | 0.289 | 0 | 0 |
| Regulation of TP53 Activity through Association with Co-factors | R-HSA-6804759 | 5.136279e-01 | 0.289 | 0 | 0 |
| Signaling by NTRKs | R-HSA-166520 | 5.146108e-01 | 0.289 | 1 | 0 |
| Gap-filling DNA repair synthesis and ligation in GG-NER | R-HSA-5696397 | 5.149887e-01 | 0.288 | 0 | 0 |
| Mitochondrial calcium ion transport | R-HSA-8949215 | 5.149887e-01 | 0.288 | 0 | 0 |
| Assembly Of The HIV Virion | R-HSA-175474 | 5.149887e-01 | 0.288 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation | R-HSA-9843743 | 5.167162e-01 | 0.287 | 0 | 0 |
| Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 | R-HSA-9844594 | 5.167162e-01 | 0.287 | 0 | 0 |
| Nuclear signaling by ERBB4 | R-HSA-1251985 | 5.167162e-01 | 0.287 | 0 | 0 |
| Regulation of RUNX3 expression and activity | R-HSA-8941858 | 5.167162e-01 | 0.287 | 0 | 0 |
| DNA Damage Bypass | R-HSA-73893 | 5.174791e-01 | 0.286 | 0 | 0 |
| Degradation of CDH1 | R-HSA-9766229 | 5.174791e-01 | 0.286 | 0 | 0 |
| Nucleotide Excision Repair | R-HSA-5696398 | 5.215500e-01 | 0.283 | 0 | 0 |
| FLT3 Signaling | R-HSA-9607240 | 5.351458e-01 | 0.272 | 0 | 0 |
| G0 and Early G1 | R-HSA-1538133 | 5.366599e-01 | 0.270 | 0 | 0 |
| Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 5.366599e-01 | 0.270 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9694676 | 5.392534e-01 | 0.268 | 0 | 0 |
| YAP1- and WWTR1 (TAZ)-stimulated gene expression | R-HSA-2032785 | 5.441478e-01 | 0.264 | 0 | 0 |
| Retrograde neurotrophin signalling | R-HSA-177504 | 5.441478e-01 | 0.264 | 0 | 0 |
| Regulation of CDH1 mRNA translation by microRNAs | R-HSA-9764562 | 5.441478e-01 | 0.264 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation | R-HSA-975163 | 5.441478e-01 | 0.264 | 0 | 0 |
| Synthesis And Processing Of GAG, GAGPOL Polyproteins | R-HSA-174495 | 5.441478e-01 | 0.264 | 0 | 0 |
| Signaling by FGFR4 in disease | R-HSA-5655291 | 5.441478e-01 | 0.264 | 0 | 0 |
| Hedgehog 'on' state | R-HSA-5632684 | 5.475997e-01 | 0.262 | 0 | 0 |
| Formation of paraxial mesoderm | R-HSA-9793380 | 5.489204e-01 | 0.260 | 0 | 0 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 5.507213e-01 | 0.259 | 0 | 0 |
| Telomere C-strand (Lagging Strand) Synthesis | R-HSA-174417 | 5.532479e-01 | 0.257 | 0 | 0 |
| Interleukin-1 family signaling | R-HSA-446652 | 5.537735e-01 | 0.257 | 0 | 0 |
| Plus-strand DNA synthesis | R-HSA-164525 | 5.553577e-01 | 0.255 | 0 | 0 |
| CDH11 homotypic and heterotypic interactions | R-HSA-9833576 | 5.553577e-01 | 0.255 | 0 | 0 |
| PKB-mediated events | R-HSA-109703 | 5.553577e-01 | 0.255 | 0 | 0 |
| PTK6 Regulates Cell Cycle | R-HSA-8849470 | 5.553577e-01 | 0.255 | 0 | 0 |
| PDE3B signalling | R-HSA-165160 | 5.553577e-01 | 0.255 | 0 | 0 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 5.553577e-01 | 0.255 | 0 | 0 |
| Inhibition of Signaling by Overexpressed EGFR | R-HSA-5638303 | 5.553577e-01 | 0.255 | 0 | 0 |
| Signaling by Overexpressed Wild-Type EGFR in Cancer | R-HSA-5638302 | 5.553577e-01 | 0.255 | 0 | 0 |
| Phase 1 - inactivation of fast Na+ channels | R-HSA-5576894 | 5.553577e-01 | 0.255 | 0 | 0 |
| TRAIL signaling | R-HSA-75158 | 5.553577e-01 | 0.255 | 0 | 0 |
| IkBA variant leads to EDA-ID | R-HSA-5603029 | 5.553577e-01 | 0.255 | 0 | 0 |
| Negative feedback regulation of MAPK pathway | R-HSA-5674499 | 5.553577e-01 | 0.255 | 0 | 0 |
| Signaling by MST1 | R-HSA-8852405 | 5.553577e-01 | 0.255 | 0 | 0 |
| SMAC, XIAP-regulated apoptotic response | R-HSA-111469 | 5.553577e-01 | 0.255 | 0 | 0 |
| Regulation of CDH19 Expression and Function | R-HSA-9764302 | 5.553577e-01 | 0.255 | 0 | 0 |
| Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660826 | 5.553577e-01 | 0.255 | 0 | 0 |
| Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant | R-HSA-2660825 | 5.553577e-01 | 0.255 | 0 | 0 |
| TYSND1 cleaves peroxisomal proteins | R-HSA-9033500 | 5.553577e-01 | 0.255 | 0 | 0 |
| Resolution of D-loop Structures through Holliday Junction Intermediates | R-HSA-5693568 | 5.569553e-01 | 0.254 | 0 | 0 |
| FGFR1 mutant receptor activation | R-HSA-1839124 | 5.569553e-01 | 0.254 | 0 | 0 |
| Interleukin-4 and Interleukin-13 signaling | R-HSA-6785807 | 5.616695e-01 | 0.251 | 0 | 0 |
| Nuclear Events (kinase and transcription factor activation) | R-HSA-198725 | 5.616778e-01 | 0.251 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE | R-HSA-77075 | 5.628051e-01 | 0.250 | 0 | 0 |
| RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | R-HSA-167160 | 5.628051e-01 | 0.250 | 0 | 0 |
| Response of EIF2AK1 (HRI) to heme deficiency | R-HSA-9648895 | 5.628051e-01 | 0.250 | 0 | 0 |
| The role of Nef in HIV-1 replication and disease pathogenesis | R-HSA-164952 | 5.628051e-01 | 0.250 | 0 | 0 |
| Growth hormone receptor signaling | R-HSA-982772 | 5.628051e-01 | 0.250 | 0 | 0 |
| rRNA processing | R-HSA-72312 | 5.686948e-01 | 0.245 | 0 | 0 |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | R-HSA-381676 | 5.709979e-01 | 0.243 | 0 | 0 |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | R-HSA-512988 | 5.709979e-01 | 0.243 | 0 | 0 |
| Cytoprotection by HMOX1 | R-HSA-9707564 | 5.730149e-01 | 0.242 | 0 | 0 |
| Spry regulation of FGF signaling | R-HSA-1295596 | 5.733049e-01 | 0.242 | 0 | 0 |
| Competing endogenous RNAs (ceRNAs) regulate PTEN translation | R-HSA-8948700 | 5.733049e-01 | 0.242 | 0 | 0 |
| TRAF6-mediated induction of TAK1 complex within TLR4 complex | R-HSA-937072 | 5.733049e-01 | 0.242 | 0 | 0 |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | R-HSA-2173791 | 5.733049e-01 | 0.242 | 0 | 0 |
| SHC1 events in EGFR signaling | R-HSA-180336 | 5.733049e-01 | 0.242 | 0 | 0 |
| Beta-catenin phosphorylation cascade | R-HSA-196299 | 5.733049e-01 | 0.242 | 0 | 0 |
| G beta:gamma signalling through BTK | R-HSA-8964315 | 5.733049e-01 | 0.242 | 0 | 0 |
| STAT3 nuclear events downstream of ALK signaling | R-HSA-9701898 | 5.733049e-01 | 0.242 | 0 | 0 |
| Biotin transport and metabolism | R-HSA-196780 | 5.733049e-01 | 0.242 | 0 | 0 |
| Other semaphorin interactions | R-HSA-416700 | 5.733049e-01 | 0.242 | 0 | 0 |
| NFE2L2 regulating anti-oxidant/detoxification enzymes | R-HSA-9818027 | 5.767625e-01 | 0.239 | 0 | 0 |
| Resolution of D-Loop Structures | R-HSA-5693537 | 5.767625e-01 | 0.239 | 0 | 0 |
| Glucagon signaling in metabolic regulation | R-HSA-163359 | 5.767625e-01 | 0.239 | 0 | 0 |
| Vpu mediated degradation of CD4 | R-HSA-180534 | 5.767625e-01 | 0.239 | 0 | 0 |
| Heme degradation | R-HSA-189483 | 5.767625e-01 | 0.239 | 0 | 0 |
| Amino acids regulate mTORC1 | R-HSA-9639288 | 5.828835e-01 | 0.234 | 0 | 0 |
| Deadenylation of mRNA | R-HSA-429947 | 5.856083e-01 | 0.232 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 1 | R-HSA-418592 | 5.856083e-01 | 0.232 | 0 | 0 |
| Mitochondrial RNA degradation | R-HSA-9836573 | 5.856083e-01 | 0.232 | 0 | 0 |
| Signaling by FLT3 ITD and TKD mutants | R-HSA-9703648 | 5.856083e-01 | 0.232 | 0 | 0 |
| PI Metabolism | R-HSA-1483255 | 5.926454e-01 | 0.227 | 0 | 0 |
| Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | R-HSA-168643 | 5.933217e-01 | 0.227 | 0 | 0 |
| Developmental Lineage of Mammary Gland Alveolar Cells | R-HSA-9927426 | 5.960560e-01 | 0.225 | 0 | 0 |
| Signaling by CSF1 (M-CSF) in myeloid cells | R-HSA-9680350 | 5.960560e-01 | 0.225 | 0 | 0 |
| NOD1/2 Signaling Pathway | R-HSA-168638 | 5.960560e-01 | 0.225 | 0 | 0 |
| Mitophagy | R-HSA-5205647 | 5.960560e-01 | 0.225 | 0 | 0 |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | R-HSA-983170 | 5.960560e-01 | 0.225 | 0 | 0 |
| Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | 5.960560e-01 | 0.225 | 0 | 0 |
| TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation | R-HSA-8869496 | 5.982094e-01 | 0.223 | 0 | 0 |
| PTK6 promotes HIF1A stabilization | R-HSA-8857538 | 5.982094e-01 | 0.223 | 0 | 0 |
| Signaling by LTK in cancer | R-HSA-9842640 | 5.982094e-01 | 0.223 | 0 | 0 |
| Uncoating of the HIV Virion | R-HSA-162585 | 5.982094e-01 | 0.223 | 0 | 0 |
| Autointegration results in viral DNA circles | R-HSA-177539 | 5.982094e-01 | 0.223 | 0 | 0 |
| RAS signaling downstream of NF1 loss-of-function variants | R-HSA-6802953 | 5.982094e-01 | 0.223 | 0 | 0 |
| Neurofascin interactions | R-HSA-447043 | 5.982094e-01 | 0.223 | 0 | 0 |
| Integration of viral DNA into host genomic DNA | R-HSA-175567 | 5.982094e-01 | 0.223 | 0 | 0 |
| VLDL assembly | R-HSA-8866423 | 5.982094e-01 | 0.223 | 0 | 0 |
| Nef and signal transduction | R-HSA-164944 | 5.982094e-01 | 0.223 | 0 | 0 |
| CREB3 factors activate genes | R-HSA-8874211 | 5.982094e-01 | 0.223 | 0 | 0 |
| Caspase activation via Death Receptors in the presence of ligand | R-HSA-140534 | 6.010785e-01 | 0.221 | 0 | 0 |
| Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 | R-HSA-1362300 | 6.010785e-01 | 0.221 | 0 | 0 |
| Prolonged ERK activation events | R-HSA-169893 | 6.010785e-01 | 0.221 | 0 | 0 |
| Atorvastatin ADME | R-HSA-9754706 | 6.010785e-01 | 0.221 | 0 | 0 |
| KSRP (KHSRP) binds and destabilizes mRNA | R-HSA-450604 | 6.010785e-01 | 0.221 | 0 | 0 |
| Regulation of NF-kappa B signaling | R-HSA-9758274 | 6.010785e-01 | 0.221 | 0 | 0 |
| Negative regulation of FLT3 | R-HSA-9706369 | 6.010785e-01 | 0.221 | 0 | 0 |
| Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells | R-HSA-210744 | 6.010785e-01 | 0.221 | 0 | 0 |
| Transcription-Coupled Nucleotide Excision Repair (TC-NER) | R-HSA-6781827 | 6.027073e-01 | 0.220 | 0 | 0 |
| SCF(Skp2)-mediated degradation of p27/p21 | R-HSA-187577 | 6.053577e-01 | 0.218 | 0 | 0 |
| G protein gated Potassium channels | R-HSA-1296059 | 6.076360e-01 | 0.216 | 0 | 0 |
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | R-HSA-997272 | 6.076360e-01 | 0.216 | 0 | 0 |
| Activation of G protein gated Potassium channels | R-HSA-1296041 | 6.076360e-01 | 0.216 | 0 | 0 |
| Polymerase switching on the C-strand of the telomere | R-HSA-174411 | 6.076360e-01 | 0.216 | 0 | 0 |
| Acyl chain remodelling of PS | R-HSA-1482801 | 6.076360e-01 | 0.216 | 0 | 0 |
| MicroRNA (miRNA) biogenesis | R-HSA-203927 | 6.076360e-01 | 0.216 | 0 | 0 |
| Glycogen breakdown (glycogenolysis) | R-HSA-70221 | 6.076360e-01 | 0.216 | 0 | 0 |
| Interleukin-7 signaling | R-HSA-1266695 | 6.076360e-01 | 0.216 | 0 | 0 |
| G alpha (z) signalling events | R-HSA-418597 | 6.138276e-01 | 0.212 | 0 | 0 |
| Signalling to ERKs | R-HSA-187687 | 6.148147e-01 | 0.211 | 1 | 0 |
| FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | R-HSA-8854050 | 6.148147e-01 | 0.211 | 0 | 0 |
| SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | 6.148147e-01 | 0.211 | 0 | 0 |
| Asymmetric localization of PCP proteins | R-HSA-4608870 | 6.219323e-01 | 0.206 | 0 | 0 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 6.219323e-01 | 0.206 | 0 | 0 |
| Somitogenesis | R-HSA-9824272 | 6.219323e-01 | 0.206 | 0 | 0 |
| Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A | R-HSA-69601 | 6.219323e-01 | 0.206 | 0 | 0 |
| p53-Independent G1/S DNA Damage Checkpoint | R-HSA-69613 | 6.219323e-01 | 0.206 | 0 | 0 |
| RNA polymerase II transcribes snRNA genes | R-HSA-6807505 | 6.236492e-01 | 0.205 | 0 | 0 |
| GRB2 events in ERBB2 signaling | R-HSA-1963640 | 6.274644e-01 | 0.202 | 0 | 0 |
| The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex | R-HSA-9931521 | 6.274644e-01 | 0.202 | 0 | 0 |
| mRNA decay by 5' to 3' exoribonuclease | R-HSA-430039 | 6.274644e-01 | 0.202 | 0 | 0 |
| Regulation of innate immune responses to cytosolic DNA | R-HSA-3134975 | 6.274644e-01 | 0.202 | 0 | 0 |
| STAT5 activation downstream of FLT3 ITD mutants | R-HSA-9702518 | 6.274644e-01 | 0.202 | 0 | 0 |
| Gap-filling DNA repair synthesis and ligation in TC-NER | R-HSA-6782210 | 6.288076e-01 | 0.201 | 0 | 0 |
| TNF signaling | R-HSA-75893 | 6.288076e-01 | 0.201 | 0 | 0 |
| MET activates PTK2 signaling | R-HSA-8874081 | 6.288686e-01 | 0.201 | 0 | 0 |
| Caspase activation via extrinsic apoptotic signalling pathway | R-HSA-5357769 | 6.288686e-01 | 0.201 | 0 | 0 |
| Activated NOTCH1 Transmits Signal to the Nucleus | R-HSA-2122948 | 6.288686e-01 | 0.201 | 0 | 0 |
| TRP channels | R-HSA-3295583 | 6.288686e-01 | 0.201 | 0 | 0 |
| Synthesis of PIPs at the Golgi membrane | R-HSA-1660514 | 6.288686e-01 | 0.201 | 0 | 0 |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | R-HSA-381426 | 6.335783e-01 | 0.198 | 0 | 0 |
| Circadian clock | R-HSA-9909396 | 6.367298e-01 | 0.196 | 0 | 0 |
| POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation | R-HSA-2892245 | 6.369335e-01 | 0.196 | 0 | 0 |
| Netrin mediated repulsion signals | R-HSA-418886 | 6.369335e-01 | 0.196 | 0 | 0 |
| IFNG signaling activates MAPKs | R-HSA-9732724 | 6.369335e-01 | 0.196 | 0 | 0 |
| Recycling of eIF2:GDP | R-HSA-72731 | 6.369335e-01 | 0.196 | 0 | 0 |
| SLBP independent Processing of Histone Pre-mRNAs | R-HSA-111367 | 6.369335e-01 | 0.196 | 0 | 0 |
| Insulin effects increased synthesis of Xylulose-5-Phosphate | R-HSA-163754 | 6.369335e-01 | 0.196 | 0 | 0 |
| Mitochondrial ABC transporters | R-HSA-1369007 | 6.369335e-01 | 0.196 | 0 | 0 |
| Microbial modulation of RIPK1-mediated regulated necrosis | R-HSA-9686347 | 6.369335e-01 | 0.196 | 0 | 0 |
| Activated NTRK3 signals through PI3K | R-HSA-9603381 | 6.369335e-01 | 0.196 | 0 | 0 |
| LDL remodeling | R-HSA-8964041 | 6.369335e-01 | 0.196 | 0 | 0 |
| VLDL clearance | R-HSA-8964046 | 6.369335e-01 | 0.196 | 0 | 0 |
| TGFBR3 regulates TGF-beta signaling | R-HSA-9839389 | 6.369335e-01 | 0.196 | 0 | 0 |
| Cation-coupled Chloride cotransporters | R-HSA-426117 | 6.369335e-01 | 0.196 | 0 | 0 |
| Defective HLCS causes multiple carboxylase deficiency | R-HSA-3371599 | 6.369335e-01 | 0.196 | 0 | 0 |
| Maturation of replicase proteins | R-HSA-9694301 | 6.369335e-01 | 0.196 | 0 | 0 |
| Regulation of TNFR1 signaling | R-HSA-5357905 | 6.380844e-01 | 0.195 | 0 | 0 |
| Toll-like Receptor Cascades | R-HSA-168898 | 6.389339e-01 | 0.195 | 1 | 0 |
| Post-translational protein modification | R-HSA-597592 | 6.436467e-01 | 0.191 | 0 | 0 |
| Cristae formation | R-HSA-8949613 | 6.492935e-01 | 0.188 | 0 | 0 |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | R-HSA-4641262 | 6.492935e-01 | 0.188 | 0 | 0 |
| Degradation of AXIN | R-HSA-4641257 | 6.506632e-01 | 0.187 | 0 | 0 |
| PI3K events in ERBB2 signaling | R-HSA-1963642 | 6.524722e-01 | 0.185 | 0 | 0 |
| Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | R-HSA-164938 | 6.524722e-01 | 0.185 | 0 | 0 |
| Uptake and function of anthrax toxins | R-HSA-5210891 | 6.524722e-01 | 0.185 | 0 | 0 |
| Regulation of cholesterol biosynthesis by SREBP (SREBF) | R-HSA-1655829 | 6.542091e-01 | 0.184 | 0 | 0 |
| ER-Phagosome pathway | R-HSA-1236974 | 6.594559e-01 | 0.181 | 0 | 0 |
| Transcriptional regulation of pluripotent stem cells | R-HSA-452723 | 6.677301e-01 | 0.175 | 0 | 0 |
| Elastic fibre formation | R-HSA-1566948 | 6.677301e-01 | 0.175 | 0 | 0 |
| SLC-mediated transport of inorganic anions | R-HSA-9958790 | 6.677301e-01 | 0.175 | 0 | 0 |
| Activation of kainate receptors upon glutamate binding | R-HSA-451326 | 6.689041e-01 | 0.175 | 0 | 0 |
| Insulin receptor recycling | R-HSA-77387 | 6.689041e-01 | 0.175 | 0 | 0 |
| Inflammasomes | R-HSA-622312 | 6.689041e-01 | 0.175 | 0 | 0 |
| GPER1 signaling | R-HSA-9634597 | 6.690776e-01 | 0.175 | 0 | 0 |
| Nuclear events stimulated by ALK signaling in cancer | R-HSA-9725371 | 6.690776e-01 | 0.175 | 0 | 0 |
| NGF-stimulated transcription | R-HSA-9031628 | 6.690776e-01 | 0.175 | 0 | 0 |
| Amino acid transport across the plasma membrane | R-HSA-352230 | 6.716517e-01 | 0.173 | 0 | 0 |
| Reverse Transcription of HIV RNA | R-HSA-162589 | 6.719276e-01 | 0.173 | 0 | 0 |
| Minus-strand DNA synthesis | R-HSA-164516 | 6.719276e-01 | 0.173 | 0 | 0 |
| Regulation by c-FLIP | R-HSA-3371378 | 6.719276e-01 | 0.173 | 0 | 0 |
| SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | R-HSA-77588 | 6.719276e-01 | 0.173 | 0 | 0 |
| Dimerization of procaspase-8 | R-HSA-69416 | 6.719276e-01 | 0.173 | 0 | 0 |
| phospho-PLA2 pathway | R-HSA-111995 | 6.719276e-01 | 0.173 | 0 | 0 |
| EGFR interacts with phospholipase C-gamma | R-HSA-212718 | 6.719276e-01 | 0.173 | 0 | 0 |
| Activated NTRK2 signals through PI3K | R-HSA-9028335 | 6.719276e-01 | 0.173 | 0 | 0 |
| Formyl peptide receptors bind formyl peptides and many other ligands | R-HSA-444473 | 6.719276e-01 | 0.173 | 0 | 0 |
| TGFBR3 PTM regulation | R-HSA-9839383 | 6.719276e-01 | 0.173 | 0 | 0 |
| Astrocytic Glutamate-Glutamine Uptake And Metabolism | R-HSA-210455 | 6.719276e-01 | 0.173 | 0 | 0 |
| Neurotransmitter uptake and metabolism In glial cells | R-HSA-112313 | 6.719276e-01 | 0.173 | 0 | 0 |
| Interleukin-23 signaling | R-HSA-9020933 | 6.719276e-01 | 0.173 | 0 | 0 |
| Mitochondrial biogenesis | R-HSA-1592230 | 6.743983e-01 | 0.171 | 0 | 0 |
| RNA Polymerase III Transcription Termination | R-HSA-73980 | 6.761222e-01 | 0.170 | 0 | 0 |
| G beta:gamma signalling through PLC beta | R-HSA-418217 | 6.761222e-01 | 0.170 | 0 | 0 |
| Trafficking of GluR2-containing AMPA receptors | R-HSA-416993 | 6.761222e-01 | 0.170 | 0 | 0 |
| Synaptic adhesion-like molecules | R-HSA-8849932 | 6.761222e-01 | 0.170 | 0 | 0 |
| Presynaptic function of Kainate receptors | R-HSA-500657 | 6.761222e-01 | 0.170 | 0 | 0 |
| PKA activation in glucagon signalling | R-HSA-164378 | 6.761222e-01 | 0.170 | 0 | 0 |
| Platelet sensitization by LDL | R-HSA-432142 | 6.761222e-01 | 0.170 | 0 | 0 |
| Nephron development | R-HSA-9831926 | 6.761222e-01 | 0.170 | 0 | 0 |
| Translation of Replicase and Assembly of the Replication Transcription Complex | R-HSA-9679504 | 6.761222e-01 | 0.170 | 0 | 0 |
| Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin | R-HSA-9725554 | 6.842160e-01 | 0.165 | 0 | 0 |
| GSK3B-mediated proteasomal degradation of PD-L1(CD274) | R-HSA-9929356 | 6.842160e-01 | 0.165 | 0 | 0 |
| Stabilization of p53 | R-HSA-69541 | 6.842160e-01 | 0.165 | 0 | 0 |
| Disease | R-HSA-1643685 | 6.863214e-01 | 0.163 | 0 | 0 |
| Glucagon-type ligand receptors | R-HSA-420092 | 6.876991e-01 | 0.163 | 0 | 0 |
| TCR signaling | R-HSA-202403 | 6.899188e-01 | 0.161 | 0 | 0 |
| Transcriptional regulation by RUNX2 | R-HSA-8878166 | 6.937939e-01 | 0.159 | 0 | 0 |
| Signaling by FGFR2 in disease | R-HSA-5655253 | 6.982734e-01 | 0.156 | 0 | 0 |
| MAP kinase activation | R-HSA-450294 | 6.983931e-01 | 0.156 | 1 | 0 |
| Impaired BRCA2 binding to PALB2 | R-HSA-9709603 | 6.984439e-01 | 0.156 | 0 | 0 |
| Prostacyclin signalling through prostacyclin receptor | R-HSA-392851 | 6.984439e-01 | 0.156 | 0 | 0 |
| Strand-asynchronous mitochondrial DNA replication | R-HSA-9913635 | 6.984439e-01 | 0.156 | 0 | 0 |
| Specification of the neural plate border | R-HSA-9834899 | 6.984439e-01 | 0.156 | 0 | 0 |
| The NLRP3 inflammasome | R-HSA-844456 | 6.984439e-01 | 0.156 | 0 | 0 |
| Other interleukin signaling | R-HSA-449836 | 6.984439e-01 | 0.156 | 0 | 0 |
| Crosslinking of collagen fibrils | R-HSA-2243919 | 6.984439e-01 | 0.156 | 0 | 0 |
| RNA Polymerase II Transcription Pre-Initiation And Promoter Opening | R-HSA-73779 | 7.001172e-01 | 0.155 | 0 | 0 |
| Formation of Incision Complex in GG-NER | R-HSA-5696395 | 7.001172e-01 | 0.155 | 0 | 0 |
| Generation of second messenger molecules | R-HSA-202433 | 7.001172e-01 | 0.155 | 0 | 0 |
| Glycogen metabolism | R-HSA-8982491 | 7.001172e-01 | 0.155 | 0 | 0 |
| CASP8 activity is inhibited | R-HSA-5218900 | 7.035506e-01 | 0.153 | 0 | 0 |
| MASTL Facilitates Mitotic Progression | R-HSA-2465910 | 7.035506e-01 | 0.153 | 0 | 0 |
| Activation of the AP-1 family of transcription factors | R-HSA-450341 | 7.035506e-01 | 0.153 | 0 | 0 |
| IRAK2 mediated activation of TAK1 complex | R-HSA-937042 | 7.035506e-01 | 0.153 | 0 | 0 |
| Regulation of commissural axon pathfinding by SLIT and ROBO | R-HSA-428542 | 7.035506e-01 | 0.153 | 0 | 0 |
| mRNA Editing | R-HSA-75072 | 7.035506e-01 | 0.153 | 0 | 0 |
| ARMS-mediated activation | R-HSA-170984 | 7.035506e-01 | 0.153 | 0 | 0 |
| Caspase activation via Dependence Receptors in the absence of ligand | R-HSA-418889 | 7.035506e-01 | 0.153 | 0 | 0 |
| Activation of the TFAP2 (AP-2) family of transcription factors | R-HSA-8866907 | 7.035506e-01 | 0.153 | 0 | 0 |
| Regulation of NPAS4 gene transcription | R-HSA-9768777 | 7.035506e-01 | 0.153 | 0 | 0 |
| Regulated proteolysis of p75NTR | R-HSA-193692 | 7.035506e-01 | 0.153 | 0 | 0 |
| Defects in biotin (Btn) metabolism | R-HSA-3323169 | 7.035506e-01 | 0.153 | 0 | 0 |
| Thrombin signalling through proteinase activated receptors (PARs) | R-HSA-456926 | 7.056822e-01 | 0.151 | 0 | 0 |
| Energy dependent regulation of mTOR by LKB1-AMPK | R-HSA-380972 | 7.056822e-01 | 0.151 | 0 | 0 |
| GABA synthesis, release, reuptake and degradation | R-HSA-888590 | 7.056822e-01 | 0.151 | 0 | 0 |
| Negative regulation of the PI3K/AKT network | R-HSA-199418 | 7.066652e-01 | 0.151 | 0 | 0 |
| Interferon gamma signaling | R-HSA-877300 | 7.089059e-01 | 0.149 | 0 | 0 |
| NCAM signaling for neurite out-growth | R-HSA-375165 | 7.112025e-01 | 0.148 | 0 | 0 |
| Hedgehog ligand biogenesis | R-HSA-5358346 | 7.121863e-01 | 0.147 | 0 | 0 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | R-HSA-110313 | 7.154334e-01 | 0.145 | 0 | 0 |
| Purine ribonucleoside monophosphate biosynthesis | R-HSA-73817 | 7.154334e-01 | 0.145 | 0 | 0 |
| Hh mutants are degraded by ERAD | R-HSA-5362768 | 7.154334e-01 | 0.145 | 0 | 0 |
| NIK-->noncanonical NF-kB signaling | R-HSA-5676590 | 7.154334e-01 | 0.145 | 0 | 0 |
| Regulation of PD-L1(CD274) translation | R-HSA-9909620 | 7.194736e-01 | 0.143 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to PALB2 loss of function | R-HSA-9701193 | 7.194736e-01 | 0.143 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | R-HSA-9704646 | 7.194736e-01 | 0.143 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | R-HSA-9701192 | 7.194736e-01 | 0.143 | 0 | 0 |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | R-HSA-9704331 | 7.194736e-01 | 0.143 | 0 | 0 |
| Formation of definitive endoderm | R-HSA-9823730 | 7.194736e-01 | 0.143 | 0 | 0 |
| BBSome-mediated cargo-targeting to cilium | R-HSA-5620922 | 7.194736e-01 | 0.143 | 0 | 0 |
| Protein hydroxylation | R-HSA-9629569 | 7.194736e-01 | 0.143 | 0 | 0 |
| Cargo concentration in the ER | R-HSA-5694530 | 7.228610e-01 | 0.141 | 0 | 0 |
| Signaling by ERBB4 | R-HSA-1236394 | 7.231522e-01 | 0.141 | 0 | 0 |
| rRNA modification in the nucleus and cytosol | R-HSA-6790901 | 7.236344e-01 | 0.140 | 0 | 0 |
| Uptake and actions of bacterial toxins | R-HSA-5339562 | 7.256402e-01 | 0.139 | 0 | 0 |
| RNA Polymerase II HIV Promoter Escape | R-HSA-167162 | 7.301662e-01 | 0.137 | 0 | 0 |
| HIV Transcription Initiation | R-HSA-167161 | 7.301662e-01 | 0.137 | 0 | 0 |
| RNA Polymerase II Transcription Initiation | R-HSA-75953 | 7.301662e-01 | 0.137 | 0 | 0 |
| Intra-Golgi traffic | R-HSA-6811438 | 7.301662e-01 | 0.137 | 0 | 0 |
| Degradation of CRY and PER proteins | R-HSA-9932298 | 7.301662e-01 | 0.137 | 0 | 0 |
| Degradation of GLI1 by the proteasome | R-HSA-5610780 | 7.301662e-01 | 0.137 | 0 | 0 |
| Negative regulation of MAPK pathway | R-HSA-5675221 | 7.301662e-01 | 0.137 | 0 | 0 |
| GLI3 is processed to GLI3R by the proteasome | R-HSA-5610785 | 7.301662e-01 | 0.137 | 0 | 0 |
| Degradation of GLI2 by the proteasome | R-HSA-5610783 | 7.301662e-01 | 0.137 | 0 | 0 |
| Binding and entry of HIV virion | R-HSA-173107 | 7.321272e-01 | 0.135 | 0 | 0 |
| Activation of Ca-permeable Kainate Receptor | R-HSA-451308 | 7.321272e-01 | 0.135 | 0 | 0 |
| DNA replication initiation | R-HSA-68952 | 7.321272e-01 | 0.135 | 0 | 0 |
| Regulation of the apoptosome activity | R-HSA-9627069 | 7.321272e-01 | 0.135 | 0 | 0 |
| Formation of apoptosome | R-HSA-111458 | 7.321272e-01 | 0.135 | 0 | 0 |
| Josephin domain DUBs | R-HSA-5689877 | 7.321272e-01 | 0.135 | 0 | 0 |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | R-HSA-5140745 | 7.321272e-01 | 0.135 | 0 | 0 |
| 2-LTR circle formation | R-HSA-164843 | 7.321272e-01 | 0.135 | 0 | 0 |
| CASP4 inflammasome assembly | R-HSA-9948001 | 7.321272e-01 | 0.135 | 0 | 0 |
| Sperm Motility And Taxes | R-HSA-1300642 | 7.321272e-01 | 0.135 | 0 | 0 |
| Tandem pore domain potassium channels | R-HSA-1296346 | 7.321272e-01 | 0.135 | 0 | 0 |
| Interleukin-27 signaling | R-HSA-9020956 | 7.321272e-01 | 0.135 | 0 | 0 |
| Maturation of spike protein | R-HSA-9683686 | 7.321272e-01 | 0.135 | 0 | 0 |
| Nucleotide biosynthesis | R-HSA-8956320 | 7.386356e-01 | 0.132 | 0 | 0 |
| Signaling by WNT in cancer | R-HSA-4791275 | 7.392467e-01 | 0.131 | 0 | 0 |
| Inwardly rectifying K+ channels | R-HSA-1296065 | 7.392467e-01 | 0.131 | 0 | 0 |
| ADP signalling through P2Y purinoceptor 12 | R-HSA-392170 | 7.392529e-01 | 0.131 | 0 | 0 |
| NOTCH2 Activation and Transmission of Signal to the Nucleus | R-HSA-2979096 | 7.392529e-01 | 0.131 | 0 | 0 |
| Signalling to RAS | R-HSA-167044 | 7.392529e-01 | 0.131 | 1 | 0 |
| JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 | R-HSA-450321 | 7.392529e-01 | 0.131 | 0 | 0 |
| Zygotic genome activation (ZGA) | R-HSA-9819196 | 7.392529e-01 | 0.131 | 0 | 0 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 7.541472e-01 | 0.123 | 0 | 0 |
| HDR through Single Strand Annealing (SSA) | R-HSA-5685938 | 7.548536e-01 | 0.122 | 0 | 0 |
| Cardiogenesis | R-HSA-9733709 | 7.548536e-01 | 0.122 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 2 Promoter | R-HSA-76066 | 7.578274e-01 | 0.120 | 0 | 0 |
| Inactivation of CSF3 (G-CSF) signaling | R-HSA-9705462 | 7.578274e-01 | 0.120 | 0 | 0 |
| Signaling by NTRK3 (TRKC) | R-HSA-9034015 | 7.578274e-01 | 0.120 | 0 | 0 |
| activated TAK1 mediates p38 MAPK activation | R-HSA-450302 | 7.578274e-01 | 0.120 | 1 | 1 |
| RNA Polymerase II Promoter Escape | R-HSA-73776 | 7.579000e-01 | 0.120 | 0 | 0 |
| Signaling by SCF-KIT | R-HSA-1433557 | 7.579000e-01 | 0.120 | 0 | 0 |
| Signaling by FGFR4 | R-HSA-5654743 | 7.579000e-01 | 0.120 | 0 | 0 |
| Hh mutants abrogate ligand secretion | R-HSA-5387390 | 7.579000e-01 | 0.120 | 0 | 0 |
| InlA-mediated entry of Listeria monocytogenes into host cells | R-HSA-8876493 | 7.579506e-01 | 0.120 | 0 | 0 |
| Ionotropic activity of kainate receptors | R-HSA-451306 | 7.579506e-01 | 0.120 | 0 | 0 |
| Activated NTRK3 signals through RAS | R-HSA-9034864 | 7.579506e-01 | 0.120 | 0 | 0 |
| vRNP Assembly | R-HSA-192905 | 7.579506e-01 | 0.120 | 0 | 0 |
| FGFRL1 modulation of FGFR1 signaling | R-HSA-5658623 | 7.579506e-01 | 0.120 | 0 | 0 |
| vRNA Synthesis | R-HSA-192814 | 7.579506e-01 | 0.120 | 0 | 0 |
| Chylomicron assembly | R-HSA-8963888 | 7.579506e-01 | 0.120 | 0 | 0 |
| Bicarbonate transporters | R-HSA-425381 | 7.579506e-01 | 0.120 | 0 | 0 |
| Alpha-protein kinase 1 signaling pathway | R-HSA-9645460 | 7.579506e-01 | 0.120 | 0 | 0 |
| Synthesis of PIPs at the ER membrane | R-HSA-1483248 | 7.579506e-01 | 0.120 | 0 | 0 |
| Biosynthesis of DPAn-3-derived maresins | R-HSA-9026290 | 7.579506e-01 | 0.120 | 0 | 0 |
| Transport of RCbl within the body | R-HSA-9758890 | 7.579506e-01 | 0.120 | 0 | 0 |
| Dissolution of Fibrin Clot | R-HSA-75205 | 7.579506e-01 | 0.120 | 0 | 0 |
| HDR through Homologous Recombination (HRR) | R-HSA-5685942 | 7.695809e-01 | 0.114 | 0 | 0 |
| SLC-mediated transport of amino acids | R-HSA-9958863 | 7.695809e-01 | 0.114 | 0 | 0 |
| G1 Phase | R-HSA-69236 | 7.709149e-01 | 0.113 | 0 | 0 |
| Cyclin D associated events in G1 | R-HSA-69231 | 7.709149e-01 | 0.113 | 0 | 0 |
| Amine ligand-binding receptors | R-HSA-375280 | 7.709149e-01 | 0.113 | 0 | 0 |
| Signaling by FGFR1 | R-HSA-5654736 | 7.748952e-01 | 0.111 | 0 | 0 |
| Notch-HLH transcription pathway | R-HSA-350054 | 7.752455e-01 | 0.111 | 0 | 0 |
| Developmental Lineage of Mammary Stem Cells | R-HSA-9938206 | 7.752455e-01 | 0.111 | 0 | 0 |
| Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants | R-HSA-9670439 | 7.752455e-01 | 0.111 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 1 Promoter | R-HSA-76061 | 7.752455e-01 | 0.111 | 0 | 0 |
| Signaling by KIT in disease | R-HSA-9669938 | 7.752455e-01 | 0.111 | 0 | 0 |
| LDL clearance | R-HSA-8964038 | 7.752455e-01 | 0.111 | 0 | 0 |
| Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy | R-HSA-9857377 | 7.752455e-01 | 0.111 | 0 | 0 |
| TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain | R-HSA-6803205 | 7.752455e-01 | 0.111 | 0 | 0 |
| Regulated Necrosis | R-HSA-5218859 | 7.801298e-01 | 0.108 | 0 | 0 |
| Condensation of Prometaphase Chromosomes | R-HSA-2514853 | 7.812860e-01 | 0.107 | 0 | 0 |
| Synthesis of diphthamide-EEF2 | R-HSA-5358493 | 7.812860e-01 | 0.107 | 0 | 0 |
| Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters | R-HSA-9931512 | 7.812860e-01 | 0.107 | 0 | 0 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 7.812860e-01 | 0.107 | 0 | 0 |
| Regulation of gene expression by Hypoxia-inducible Factor | R-HSA-1234158 | 7.812860e-01 | 0.107 | 0 | 0 |
| Activated NTRK2 signals through RAS | R-HSA-9026519 | 7.812860e-01 | 0.107 | 0 | 0 |
| Plasmalogen biosynthesis | R-HSA-75896 | 7.812860e-01 | 0.107 | 0 | 0 |
| NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis | R-HSA-9623433 | 7.812860e-01 | 0.107 | 0 | 0 |
| Inhibition of replication initiation of damaged DNA by RB1/E2F1 | R-HSA-113501 | 7.812860e-01 | 0.107 | 0 | 0 |
| Viral RNP Complexes in the Host Cell Nucleus | R-HSA-168330 | 7.812860e-01 | 0.107 | 0 | 0 |
| Proton-coupled monocarboxylate transport | R-HSA-433692 | 7.812860e-01 | 0.107 | 0 | 0 |
| RNA Polymerase II Transcription Initiation And Promoter Clearance | R-HSA-76042 | 7.833737e-01 | 0.106 | 0 | 0 |
| Signaling by FGFR3 | R-HSA-5654741 | 7.833737e-01 | 0.106 | 0 | 0 |
| ADORA2B mediated anti-inflammatory cytokines production | R-HSA-9660821 | 7.833737e-01 | 0.106 | 0 | 0 |
| Defective CFTR causes cystic fibrosis | R-HSA-5678895 | 7.833737e-01 | 0.106 | 0 | 0 |
| Dectin-1 mediated noncanonical NF-kB signaling | R-HSA-5607761 | 7.833737e-01 | 0.106 | 0 | 0 |
| Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | R-HSA-6814122 | 7.838007e-01 | 0.106 | 0 | 0 |
| Signal amplification | R-HSA-392518 | 7.838007e-01 | 0.106 | 0 | 0 |
| SARS-CoV-1 modulates host translation machinery | R-HSA-9735869 | 7.838007e-01 | 0.106 | 0 | 0 |
| Signaling by NOTCH2 | R-HSA-1980145 | 7.838007e-01 | 0.106 | 0 | 0 |
| Regulation of TLR by endogenous ligand | R-HSA-5686938 | 7.838007e-01 | 0.106 | 0 | 0 |
| BMAL1:CLOCK,NPAS2 activates circadian expression | R-HSA-1368108 | 7.838007e-01 | 0.106 | 0 | 0 |
| IRS-mediated signalling | R-HSA-112399 | 7.860875e-01 | 0.105 | 0 | 0 |
| ABC-family proteins mediated transport | R-HSA-382556 | 7.897831e-01 | 0.102 | 0 | 0 |
| Regulation of PTEN mRNA translation | R-HSA-8943723 | 7.915575e-01 | 0.102 | 0 | 0 |
| Synthesis of UDP-N-acetyl-glucosamine | R-HSA-446210 | 7.915575e-01 | 0.102 | 0 | 0 |
| Biosynthesis of maresins | R-HSA-9018682 | 7.915575e-01 | 0.102 | 0 | 0 |
| Formation of the ureteric bud | R-HSA-9830674 | 7.915575e-01 | 0.102 | 0 | 0 |
| Mitochondrial mRNA modification | R-HSA-9937008 | 7.915575e-01 | 0.102 | 0 | 0 |
| Inactivation, recovery and regulation of the phototransduction cascade | R-HSA-2514859 | 7.952871e-01 | 0.099 | 0 | 0 |
| NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux | R-HSA-9029569 | 7.968426e-01 | 0.099 | 0 | 0 |
| PERK regulates gene expression | R-HSA-381042 | 7.971806e-01 | 0.098 | 0 | 0 |
| Interleukin-1 signaling | R-HSA-9020702 | 7.980716e-01 | 0.098 | 0 | 0 |
| COPII-mediated vesicle transport | R-HSA-204005 | 8.001253e-01 | 0.097 | 0 | 0 |
| Interleukin-17 signaling | R-HSA-448424 | 8.001253e-01 | 0.097 | 1 | 0 |
| Scavenging by Class F Receptors | R-HSA-3000484 | 8.023729e-01 | 0.096 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD Domain Mutants | R-HSA-2691232 | 8.023729e-01 | 0.096 | 0 | 0 |
| Signaling by NOTCH1 HD Domain Mutants in Cancer | R-HSA-2691230 | 8.023729e-01 | 0.096 | 0 | 0 |
| Role of second messengers in netrin-1 signaling | R-HSA-418890 | 8.023729e-01 | 0.096 | 0 | 0 |
| VLDLR internalisation and degradation | R-HSA-8866427 | 8.023729e-01 | 0.096 | 0 | 0 |
| Serotonin clearance from the synaptic cleft | R-HSA-380615 | 8.023729e-01 | 0.096 | 0 | 0 |
| Regulation of FOXO transcriptional activity by acetylation | R-HSA-9617629 | 8.023729e-01 | 0.096 | 0 | 0 |
| SHC-related events triggered by IGF1R | R-HSA-2428933 | 8.023729e-01 | 0.096 | 0 | 0 |
| Biosynthesis of DPAn-3-derived protectins and resolvins | R-HSA-9026286 | 8.023729e-01 | 0.096 | 0 | 0 |
| Activated NTRK2 signals through FRS2 and FRS3 | R-HSA-9028731 | 8.023729e-01 | 0.096 | 0 | 0 |
| Trafficking and processing of endosomal TLR | R-HSA-1679131 | 8.023729e-01 | 0.096 | 0 | 0 |
| IRAK1 recruits IKK complex | R-HSA-937039 | 8.023729e-01 | 0.096 | 0 | 0 |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | R-HSA-975144 | 8.023729e-01 | 0.096 | 0 | 0 |
| NOTCH2 intracellular domain regulates transcription | R-HSA-2197563 | 8.023729e-01 | 0.096 | 0 | 0 |
| p75NTR recruits signalling complexes | R-HSA-209543 | 8.023729e-01 | 0.096 | 0 | 0 |
| Interleukin-35 Signalling | R-HSA-8984722 | 8.023729e-01 | 0.096 | 0 | 0 |
| Reversal of alkylation damage by DNA dioxygenases | R-HSA-73943 | 8.023729e-01 | 0.096 | 0 | 0 |
| Interleukin-15 signaling | R-HSA-8983432 | 8.023729e-01 | 0.096 | 0 | 0 |
| Thromboxane signalling through TP receptor | R-HSA-428930 | 8.068147e-01 | 0.093 | 0 | 0 |
| TRAF6 mediated NF-kB activation | R-HSA-933542 | 8.068147e-01 | 0.093 | 0 | 0 |
| Deadenylation-dependent mRNA decay | R-HSA-429914 | 8.071680e-01 | 0.093 | 0 | 0 |
| Extension of Telomeres | R-HSA-180786 | 8.071680e-01 | 0.093 | 0 | 0 |
| Assembly of collagen fibrils and other multimeric structures | R-HSA-2022090 | 8.071680e-01 | 0.093 | 0 | 0 |
| Metabolism of proteins | R-HSA-392499 | 8.082218e-01 | 0.092 | 0 | 0 |
| Signaling by Insulin receptor | R-HSA-74752 | 8.089974e-01 | 0.092 | 0 | 0 |
| RNA Polymerase III Abortive And Retractive Initiation | R-HSA-749476 | 8.098605e-01 | 0.092 | 0 | 0 |
| RNA Polymerase III Transcription | R-HSA-74158 | 8.098605e-01 | 0.092 | 0 | 0 |
| RUNX2 regulates bone development | R-HSA-8941326 | 8.098605e-01 | 0.092 | 0 | 0 |
| FGFR2 mutant receptor activation | R-HSA-1839126 | 8.098605e-01 | 0.092 | 0 | 0 |
| Signaling by NOTCH1 PEST Domain Mutants in Cancer | R-HSA-2644602 | 8.170717e-01 | 0.088 | 0 | 0 |
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | R-HSA-2894862 | 8.170717e-01 | 0.088 | 0 | 0 |
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | R-HSA-2644606 | 8.170717e-01 | 0.088 | 0 | 0 |
| Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | R-HSA-2894858 | 8.170717e-01 | 0.088 | 0 | 0 |
| Signaling by NOTCH1 in Cancer | R-HSA-2644603 | 8.170717e-01 | 0.088 | 0 | 0 |
| tRNA Aminoacylation | R-HSA-379724 | 8.170717e-01 | 0.088 | 0 | 0 |
| Translation | R-HSA-72766 | 8.185373e-01 | 0.087 | 0 | 0 |
| Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | R-HSA-5693554 | 8.210689e-01 | 0.086 | 0 | 0 |
| Laminin interactions | R-HSA-3000157 | 8.210689e-01 | 0.086 | 0 | 0 |
| Tight junction interactions | R-HSA-420029 | 8.210689e-01 | 0.086 | 0 | 0 |
| Synthesis of PIPs at the early endosome membrane | R-HSA-1660516 | 8.210689e-01 | 0.086 | 0 | 0 |
| PIWI-interacting RNA (piRNA) biogenesis | R-HSA-5601884 | 8.210689e-01 | 0.086 | 0 | 0 |
| Microbial factors inhibit CASP4 activity | R-HSA-9956593 | 8.214279e-01 | 0.085 | 0 | 0 |
| Platelet Adhesion to exposed collagen | R-HSA-75892 | 8.214279e-01 | 0.085 | 0 | 0 |
| PI5P Regulates TP53 Acetylation | R-HSA-6811555 | 8.214279e-01 | 0.085 | 0 | 0 |
| Interleukin-6 signaling | R-HSA-1059683 | 8.214279e-01 | 0.085 | 0 | 0 |
| Ovarian tumor domain proteases | R-HSA-5689896 | 8.218637e-01 | 0.085 | 0 | 0 |
| IRS-related events triggered by IGF1R | R-HSA-2428928 | 8.265627e-01 | 0.083 | 0 | 0 |
| Aquaporin-mediated transport | R-HSA-445717 | 8.265627e-01 | 0.083 | 0 | 0 |
| p53-Dependent G1/S DNA damage checkpoint | R-HSA-69580 | 8.278788e-01 | 0.082 | 0 | 0 |
| p53-Dependent G1 DNA Damage Response | R-HSA-69563 | 8.278788e-01 | 0.082 | 0 | 0 |
| Adrenaline,noradrenaline inhibits insulin secretion | R-HSA-400042 | 8.343716e-01 | 0.079 | 0 | 0 |
| Sphingolipid catabolism | R-HSA-9845614 | 8.343716e-01 | 0.079 | 0 | 0 |
| Developmental Cell Lineages | R-HSA-9734767 | 8.346479e-01 | 0.078 | 0 | 0 |
| Mitochondrial protein import | R-HSA-1268020 | 8.356503e-01 | 0.078 | 0 | 0 |
| PI3K Cascade | R-HSA-109704 | 8.377384e-01 | 0.077 | 0 | 0 |
| SLC transporter disorders | R-HSA-5619102 | 8.378203e-01 | 0.077 | 0 | 0 |
| ERBB2 Activates PTK6 Signaling | R-HSA-8847993 | 8.386466e-01 | 0.076 | 0 | 0 |
| CLEC7A (Dectin-1) induces NFAT activation | R-HSA-5607763 | 8.386466e-01 | 0.076 | 0 | 0 |
| Hydrolysis of LPC | R-HSA-1483115 | 8.386466e-01 | 0.076 | 0 | 0 |
| Biosynthesis of E-series 18(R)-resolvins | R-HSA-9023661 | 8.386466e-01 | 0.076 | 0 | 0 |
| MAP3K8 (TPL2)-dependent MAPK1/3 activation | R-HSA-5684264 | 8.386466e-01 | 0.076 | 0 | 0 |
| cGMP effects | R-HSA-418457 | 8.386466e-01 | 0.076 | 0 | 0 |
| Formation of the active cofactor, UDP-glucuronate | R-HSA-173599 | 8.386466e-01 | 0.076 | 0 | 0 |
| Physiological factors | R-HSA-5578768 | 8.386466e-01 | 0.076 | 0 | 0 |
| NRIF signals cell death from the nucleus | R-HSA-205043 | 8.386466e-01 | 0.076 | 0 | 0 |
| Respiratory syncytial virus genome transcription | R-HSA-9828642 | 8.386466e-01 | 0.076 | 0 | 0 |
| Non-canonical inflammasome activation | R-HSA-9686114 | 8.386466e-01 | 0.076 | 0 | 0 |
| Acyl chain remodeling of CL | R-HSA-1482798 | 8.386466e-01 | 0.076 | 0 | 0 |
| Interferon alpha/beta signaling | R-HSA-909733 | 8.395496e-01 | 0.076 | 0 | 0 |
| Iron uptake and transport | R-HSA-917937 | 8.439345e-01 | 0.074 | 0 | 0 |
| RAS processing | R-HSA-9648002 | 8.439365e-01 | 0.074 | 0 | 0 |
| Signaling by ALK | R-HSA-201556 | 8.439365e-01 | 0.074 | 0 | 0 |
| G1/S DNA Damage Checkpoints | R-HSA-69615 | 8.443443e-01 | 0.073 | 0 | 0 |
| Regulation of TP53 Activity through Phosphorylation | R-HSA-6804756 | 8.449568e-01 | 0.073 | 0 | 0 |
| Signaling by FGFR3 in disease | R-HSA-5655332 | 8.467736e-01 | 0.072 | 0 | 0 |
| Signaling by NTRK2 (TRKB) | R-HSA-9006115 | 8.467736e-01 | 0.072 | 0 | 0 |
| Maturation of hRSV A proteins | R-HSA-9828806 | 8.467736e-01 | 0.072 | 0 | 0 |
| The phototransduction cascade | R-HSA-2514856 | 8.471203e-01 | 0.072 | 0 | 0 |
| Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | R-HSA-1234176 | 8.471203e-01 | 0.072 | 0 | 0 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 8.497525e-01 | 0.071 | 0 | 0 |
| Signaling by NOTCH1 | R-HSA-1980143 | 8.516893e-01 | 0.070 | 0 | 0 |
| Insulin receptor signalling cascade | R-HSA-74751 | 8.526552e-01 | 0.069 | 0 | 0 |
| IGF1R signaling cascade | R-HSA-2428924 | 8.526552e-01 | 0.069 | 0 | 0 |
| Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 8.540556e-01 | 0.069 | 0 | 0 |
| Diseases of Immune System | R-HSA-5260271 | 8.540556e-01 | 0.069 | 0 | 0 |
| Mitochondrial tRNA aminoacylation | R-HSA-379726 | 8.540556e-01 | 0.069 | 0 | 0 |
| RNA Polymerase III Chain Elongation | R-HSA-73780 | 8.542059e-01 | 0.068 | 0 | 0 |
| ERBB2 Regulates Cell Motility | R-HSA-6785631 | 8.542059e-01 | 0.068 | 0 | 0 |
| Translesion synthesis by REV1 | R-HSA-110312 | 8.542059e-01 | 0.068 | 0 | 0 |
| Telomere C-strand synthesis initiation | R-HSA-174430 | 8.542059e-01 | 0.068 | 0 | 0 |
| Signaling by Activin | R-HSA-1502540 | 8.542059e-01 | 0.068 | 0 | 0 |
| p38MAPK events | R-HSA-171007 | 8.542059e-01 | 0.068 | 1 | 1 |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | R-HSA-9673767 | 8.542059e-01 | 0.068 | 0 | 0 |
| Signaling by PDGFRA extracellular domain mutants | R-HSA-9673770 | 8.542059e-01 | 0.068 | 0 | 0 |
| p75NTR signals via NF-kB | R-HSA-193639 | 8.542059e-01 | 0.068 | 0 | 0 |
| Formation of the anterior neural plate | R-HSA-9823739 | 8.542059e-01 | 0.068 | 0 | 0 |
| DNA Damage Reversal | R-HSA-73942 | 8.542059e-01 | 0.068 | 0 | 0 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 8.557873e-01 | 0.068 | 0 | 0 |
| Stimuli-sensing channels | R-HSA-2672351 | 8.557873e-01 | 0.068 | 0 | 0 |
| AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) | R-HSA-9931269 | 8.560397e-01 | 0.068 | 0 | 0 |
| Transcriptional Regulation by NPAS4 | R-HSA-9634815 | 8.560397e-01 | 0.068 | 0 | 0 |
| Negative regulation of FGFR3 signaling | R-HSA-5654732 | 8.583250e-01 | 0.066 | 0 | 0 |
| RUNX2 regulates osteoblast differentiation | R-HSA-8940973 | 8.583250e-01 | 0.066 | 0 | 0 |
| tRNA processing | R-HSA-72306 | 8.589523e-01 | 0.066 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9694635 | 8.591258e-01 | 0.066 | 0 | 0 |
| Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) | R-HSA-2404192 | 8.605934e-01 | 0.065 | 0 | 0 |
| Cellular response to hypoxia | R-HSA-1234174 | 8.605934e-01 | 0.065 | 0 | 0 |
| Gastrulation | R-HSA-9758941 | 8.619454e-01 | 0.065 | 0 | 0 |
| Maturation of spike protein | R-HSA-9694548 | 8.635966e-01 | 0.064 | 0 | 0 |
| Integrin cell surface interactions | R-HSA-216083 | 8.662520e-01 | 0.062 | 0 | 0 |
| ABC transporter disorders | R-HSA-5619084 | 8.662520e-01 | 0.062 | 0 | 0 |
| Translesion synthesis by POLI | R-HSA-5656121 | 8.682657e-01 | 0.061 | 0 | 0 |
| Entry of Influenza Virion into Host Cell via Endocytosis | R-HSA-168275 | 8.682657e-01 | 0.061 | 0 | 0 |
| Killing mechanisms | R-HSA-9664420 | 8.682657e-01 | 0.061 | 0 | 0 |
| WNT5:FZD7-mediated leishmania damping | R-HSA-9673324 | 8.682657e-01 | 0.061 | 0 | 0 |
| Class I peroxisomal membrane protein import | R-HSA-9603798 | 8.682657e-01 | 0.061 | 0 | 0 |
| Phase 4 - resting membrane potential | R-HSA-5576886 | 8.682657e-01 | 0.061 | 0 | 0 |
| Activation of the phototransduction cascade | R-HSA-2485179 | 8.682657e-01 | 0.061 | 0 | 0 |
| Regulation of glycolysis by fructose 2,6-bisphosphate metabolism | R-HSA-9634600 | 8.682657e-01 | 0.061 | 0 | 0 |
| Serotonin and melatonin biosynthesis | R-HSA-209931 | 8.682657e-01 | 0.061 | 0 | 0 |
| Induction of Cell-Cell Fusion | R-HSA-9733458 | 8.682657e-01 | 0.061 | 0 | 0 |
| SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | R-HSA-399955 | 8.682657e-01 | 0.061 | 0 | 0 |
| Virus Assembly and Release | R-HSA-168268 | 8.682657e-01 | 0.061 | 0 | 0 |
| Impaired BRCA2 binding to RAD51 | R-HSA-9709570 | 8.690744e-01 | 0.061 | 0 | 0 |
| Negative regulation of FGFR4 signaling | R-HSA-5654733 | 8.690744e-01 | 0.061 | 0 | 0 |
| Signaling by CSF3 (G-CSF) | R-HSA-9674555 | 8.690744e-01 | 0.061 | 0 | 0 |
| Downstream signaling of activated FGFR3 | R-HSA-5654708 | 8.690744e-01 | 0.061 | 0 | 0 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 8.690744e-01 | 0.061 | 0 | 0 |
| Regulation of gene expression in beta cells | R-HSA-210745 | 8.690744e-01 | 0.061 | 0 | 0 |
| Neurotransmitter release cycle | R-HSA-112310 | 8.723417e-01 | 0.059 | 0 | 0 |
| Translation of Structural Proteins | R-HSA-9683701 | 8.725843e-01 | 0.059 | 0 | 0 |
| Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 8.743811e-01 | 0.058 | 0 | 0 |
| Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 8.778868e-01 | 0.057 | 0 | 0 |
| RNA Polymerase III Transcription Initiation | R-HSA-76046 | 8.790691e-01 | 0.056 | 0 | 0 |
| DAP12 signaling | R-HSA-2424491 | 8.790691e-01 | 0.056 | 0 | 0 |
| Downstream signaling of activated FGFR4 | R-HSA-5654716 | 8.790691e-01 | 0.056 | 0 | 0 |
| Selenoamino acid metabolism | R-HSA-2408522 | 8.795837e-01 | 0.056 | 0 | 0 |
| Toll Like Receptor TLR1:TLR2 Cascade | R-HSA-168179 | 8.805397e-01 | 0.055 | 1 | 0 |
| Toll Like Receptor 2 (TLR2) Cascade | R-HSA-181438 | 8.805397e-01 | 0.055 | 1 | 0 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | R-HSA-2892247 | 8.809704e-01 | 0.055 | 0 | 0 |
| Translesion synthesis by POLK | R-HSA-5655862 | 8.809704e-01 | 0.055 | 0 | 0 |
| SHC1 events in ERBB4 signaling | R-HSA-1250347 | 8.809704e-01 | 0.055 | 0 | 0 |
| Fibronectin matrix formation | R-HSA-1566977 | 8.809704e-01 | 0.055 | 0 | 0 |
| Acetylcholine regulates insulin secretion | R-HSA-399997 | 8.809704e-01 | 0.055 | 0 | 0 |
| Passive transport by Aquaporins | R-HSA-432047 | 8.809704e-01 | 0.055 | 0 | 0 |
| Coenzyme A biosynthesis | R-HSA-196783 | 8.809704e-01 | 0.055 | 0 | 0 |
| Biosynthesis of maresin-like SPMs | R-HSA-9027307 | 8.809704e-01 | 0.055 | 0 | 0 |
| Cytosolic tRNA aminoacylation | R-HSA-379716 | 8.810438e-01 | 0.055 | 0 | 0 |
| GABA B receptor activation | R-HSA-977444 | 8.810438e-01 | 0.055 | 0 | 0 |
| Activation of GABAB receptors | R-HSA-991365 | 8.810438e-01 | 0.055 | 0 | 0 |
| Toll Like Receptor 7/8 (TLR7/8) Cascade | R-HSA-168181 | 8.846249e-01 | 0.053 | 1 | 0 |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | R-HSA-6811558 | 8.856326e-01 | 0.053 | 0 | 0 |
| Extracellular matrix organization | R-HSA-1474244 | 8.868184e-01 | 0.052 | 0 | 0 |
| Respiratory syncytial virus (RSV) attachment and entry | R-HSA-9820960 | 8.883545e-01 | 0.051 | 0 | 0 |
| Downstream signal transduction | R-HSA-186763 | 8.883545e-01 | 0.051 | 0 | 0 |
| Neddylation | R-HSA-8951664 | 8.895216e-01 | 0.051 | 0 | 0 |
| Late SARS-CoV-2 Infection Events | R-HSA-9772573 | 8.901498e-01 | 0.051 | 0 | 0 |
| Biosynthesis of aspirin-triggered D-series resolvins | R-HSA-9020265 | 8.924505e-01 | 0.049 | 0 | 0 |
| Sulfide oxidation to sulfate | R-HSA-1614517 | 8.924505e-01 | 0.049 | 0 | 0 |
| Regulation of FZD by ubiquitination | R-HSA-4641263 | 8.924505e-01 | 0.049 | 0 | 0 |
| Synthesis of PIPs at the late endosome membrane | R-HSA-1660517 | 8.924505e-01 | 0.049 | 0 | 0 |
| Choline catabolism | R-HSA-6798163 | 8.924505e-01 | 0.049 | 0 | 0 |
| Regulation of lipid metabolism by PPARalpha | R-HSA-400206 | 8.989967e-01 | 0.046 | 0 | 0 |
| Toll Like Receptor 9 (TLR9) Cascade | R-HSA-168138 | 8.995257e-01 | 0.046 | 1 | 0 |
| Mitochondrial protein degradation | R-HSA-9837999 | 9.008223e-01 | 0.045 | 0 | 0 |
| Metabolism of cofactors | R-HSA-8978934 | 9.010185e-01 | 0.045 | 0 | 0 |
| Disorders of transmembrane transporters | R-HSA-5619115 | 9.018380e-01 | 0.045 | 0 | 0 |
| Apoptotic factor-mediated response | R-HSA-111471 | 9.028240e-01 | 0.044 | 0 | 0 |
| Regulation of TP53 Activity through Methylation | R-HSA-6804760 | 9.028240e-01 | 0.044 | 0 | 0 |
| Biosynthesis of Lipoxins (LX) | R-HSA-2142700 | 9.028240e-01 | 0.044 | 0 | 0 |
| FOXO-mediated transcription of cell death genes | R-HSA-9614657 | 9.028240e-01 | 0.044 | 0 | 0 |
| Tie2 Signaling | R-HSA-210993 | 9.028240e-01 | 0.044 | 0 | 0 |
| Negative regulation of FGFR1 signaling | R-HSA-5654726 | 9.049711e-01 | 0.043 | 0 | 0 |
| Regulation of beta-cell development | R-HSA-186712 | 9.068450e-01 | 0.042 | 0 | 0 |
| Formation of TC-NER Pre-Incision Complex | R-HSA-6781823 | 9.100814e-01 | 0.041 | 0 | 0 |
| Diseases of DNA repair | R-HSA-9675135 | 9.100814e-01 | 0.041 | 0 | 0 |
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 9.117842e-01 | 0.040 | 0 | 0 |
| PI-3K cascade:FGFR3 | R-HSA-5654710 | 9.121974e-01 | 0.040 | 0 | 0 |
| Translesion Synthesis by POLH | R-HSA-110320 | 9.121974e-01 | 0.040 | 0 | 0 |
| Pyrimidine biosynthesis | R-HSA-500753 | 9.121974e-01 | 0.040 | 0 | 0 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 9.121974e-01 | 0.040 | 0 | 0 |
| Acyl chain remodelling of PC | R-HSA-1482788 | 9.123843e-01 | 0.040 | 0 | 0 |
| Miscellaneous transport and binding events | R-HSA-5223345 | 9.123843e-01 | 0.040 | 0 | 0 |
| Sphingolipid de novo biosynthesis | R-HSA-1660661 | 9.126297e-01 | 0.040 | 0 | 0 |
| Metabolism of polyamines | R-HSA-351202 | 9.126297e-01 | 0.040 | 0 | 0 |
| Regulation of PD-L1(CD274) Post-translational modification | R-HSA-9909615 | 9.131034e-01 | 0.039 | 0 | 0 |
| TAK1-dependent IKK and NF-kappa-B activation | R-HSA-445989 | 9.162571e-01 | 0.038 | 0 | 0 |
| TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | R-HSA-975138 | 9.178077e-01 | 0.037 | 1 | 0 |
| Regulation of RUNX2 expression and activity | R-HSA-8939902 | 9.180921e-01 | 0.037 | 0 | 0 |
| Negative regulation of FGFR2 signaling | R-HSA-5654727 | 9.192521e-01 | 0.037 | 0 | 0 |
| Diseases of DNA Double-Strand Break Repair | R-HSA-9675136 | 9.192521e-01 | 0.037 | 0 | 0 |
| Defective homologous recombination repair (HRR) due to BRCA2 loss of function | R-HSA-9701190 | 9.192521e-01 | 0.037 | 0 | 0 |
| Calnexin/calreticulin cycle | R-HSA-901042 | 9.192521e-01 | 0.037 | 0 | 0 |
| PI-3K cascade:FGFR4 | R-HSA-5654720 | 9.206673e-01 | 0.036 | 0 | 0 |
| Formation of ATP by chemiosmotic coupling | R-HSA-163210 | 9.206673e-01 | 0.036 | 0 | 0 |
| Signaling by NODAL | R-HSA-1181150 | 9.206673e-01 | 0.036 | 0 | 0 |
| Mitochondrial iron-sulfur cluster biogenesis | R-HSA-1362409 | 9.206673e-01 | 0.036 | 0 | 0 |
| Wax and plasmalogen biosynthesis | R-HSA-8848584 | 9.206673e-01 | 0.036 | 0 | 0 |
| Acyl chain remodelling of PI | R-HSA-1482922 | 9.206673e-01 | 0.036 | 0 | 0 |
| Common Pathway of Fibrin Clot Formation | R-HSA-140875 | 9.206673e-01 | 0.036 | 0 | 0 |
| Synthesis of Ketone Bodies | R-HSA-77111 | 9.206673e-01 | 0.036 | 0 | 0 |
| Glycogen synthesis | R-HSA-3322077 | 9.206673e-01 | 0.036 | 0 | 0 |
| MyD88 dependent cascade initiated on endosome | R-HSA-975155 | 9.218540e-01 | 0.035 | 1 | 0 |
| Signaling by PDGF | R-HSA-186797 | 9.232467e-01 | 0.035 | 0 | 0 |
| MyD88 cascade initiated on plasma membrane | R-HSA-975871 | 9.237081e-01 | 0.034 | 1 | 0 |
| Toll Like Receptor 10 (TLR10) Cascade | R-HSA-168142 | 9.237081e-01 | 0.034 | 1 | 0 |
| Toll Like Receptor 5 (TLR5) Cascade | R-HSA-168176 | 9.237081e-01 | 0.034 | 1 | 0 |
| Downstream signaling of activated FGFR2 | R-HSA-5654696 | 9.256108e-01 | 0.034 | 0 | 0 |
| Downstream signaling of activated FGFR1 | R-HSA-5654687 | 9.256108e-01 | 0.034 | 0 | 0 |
| Acyl chain remodelling of PE | R-HSA-1482839 | 9.256108e-01 | 0.034 | 0 | 0 |
| Presynaptic phase of homologous DNA pairing and strand exchange | R-HSA-5693616 | 9.256108e-01 | 0.034 | 0 | 0 |
| Oncogene Induced Senescence | R-HSA-2559585 | 9.256108e-01 | 0.034 | 0 | 0 |
| Transferrin endocytosis and recycling | R-HSA-917977 | 9.256108e-01 | 0.034 | 0 | 0 |
| Asparagine N-linked glycosylation | R-HSA-446203 | 9.259431e-01 | 0.033 | 0 | 0 |
| NOTCH1 Intracellular Domain Regulates Transcription | R-HSA-2122947 | 9.274623e-01 | 0.033 | 0 | 0 |
| MyD88 deficiency (TLR2/4) | R-HSA-5602498 | 9.283205e-01 | 0.032 | 0 | 0 |
| SHC-mediated cascade:FGFR3 | R-HSA-5654704 | 9.283205e-01 | 0.032 | 0 | 0 |
| Matriglycan biosynthesis on DAG1 | R-HSA-9939291 | 9.283205e-01 | 0.032 | 0 | 0 |
| Acetylcholine Neurotransmitter Release Cycle | R-HSA-264642 | 9.283205e-01 | 0.032 | 0 | 0 |
| Biosynthesis of E-series 18(S)-resolvins | R-HSA-9018896 | 9.283205e-01 | 0.032 | 0 | 0 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 9.283205e-01 | 0.032 | 0 | 0 |
| Acyl chain remodelling of PG | R-HSA-1482925 | 9.283205e-01 | 0.032 | 0 | 0 |
| Prevention of phagosomal-lysosomal fusion | R-HSA-9636383 | 9.283205e-01 | 0.032 | 0 | 0 |
| NR1H2 and NR1H3-mediated signaling | R-HSA-9024446 | 9.308420e-01 | 0.031 | 0 | 0 |
| GPVI-mediated activation cascade | R-HSA-114604 | 9.314947e-01 | 0.031 | 0 | 0 |
| Triglyceride catabolism | R-HSA-163560 | 9.314947e-01 | 0.031 | 0 | 0 |
| PPARA activates gene expression | R-HSA-1989781 | 9.332918e-01 | 0.030 | 0 | 0 |
| Downstream TCR signaling | R-HSA-202424 | 9.345154e-01 | 0.029 | 0 | 0 |
| IRAK4 deficiency (TLR2/4) | R-HSA-5603041 | 9.352358e-01 | 0.029 | 0 | 0 |
| SHC-mediated cascade:FGFR4 | R-HSA-5654719 | 9.352358e-01 | 0.029 | 0 | 0 |
| FRS-mediated FGFR3 signaling | R-HSA-5654706 | 9.352358e-01 | 0.029 | 0 | 0 |
| Metabolism of Angiotensinogen to Angiotensins | R-HSA-2022377 | 9.352358e-01 | 0.029 | 0 | 0 |
| Voltage gated Potassium channels | R-HSA-1296072 | 9.369361e-01 | 0.028 | 0 | 0 |
| Formation of the cornified envelope | R-HSA-6809371 | 9.380410e-01 | 0.028 | 0 | 0 |
| PI-3K cascade:FGFR1 | R-HSA-5654689 | 9.414844e-01 | 0.026 | 0 | 0 |
| Regulation of IFNA/IFNB signaling | R-HSA-912694 | 9.414844e-01 | 0.026 | 0 | 0 |
| RNA Polymerase III Transcription Initiation From Type 3 Promoter | R-HSA-76071 | 9.414844e-01 | 0.026 | 0 | 0 |
| Biosynthesis of D-series resolvins | R-HSA-9018676 | 9.414844e-01 | 0.026 | 0 | 0 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 9.414844e-01 | 0.026 | 0 | 0 |
| FRS-mediated FGFR4 signaling | R-HSA-5654712 | 9.414844e-01 | 0.026 | 0 | 0 |
| Cholesterol biosynthesis via lathosterol | R-HSA-6807062 | 9.414844e-01 | 0.026 | 0 | 0 |
| Cellular hexose transport | R-HSA-189200 | 9.414844e-01 | 0.026 | 0 | 0 |
| Homologous DNA Pairing and Strand Exchange | R-HSA-5693579 | 9.419657e-01 | 0.026 | 0 | 0 |
| Kidney development | R-HSA-9830369 | 9.448899e-01 | 0.025 | 0 | 0 |
| Integration of energy metabolism | R-HSA-163685 | 9.455379e-01 | 0.024 | 0 | 0 |
| G alpha (s) signalling events | R-HSA-418555 | 9.464941e-01 | 0.024 | 0 | 0 |
| Pentose phosphate pathway | R-HSA-71336 | 9.466122e-01 | 0.024 | 0 | 0 |
| Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) | R-HSA-381771 | 9.466122e-01 | 0.024 | 0 | 0 |
| Plasma lipoprotein clearance | R-HSA-8964043 | 9.466122e-01 | 0.024 | 0 | 0 |
| Interleukin receptor SHC signaling | R-HSA-912526 | 9.471304e-01 | 0.024 | 0 | 0 |
| Organic anion transport by SLCO transporters | R-HSA-879518 | 9.471304e-01 | 0.024 | 0 | 0 |
| Carnitine shuttle | R-HSA-200425 | 9.471304e-01 | 0.024 | 0 | 0 |
| Ketone body metabolism | R-HSA-74182 | 9.471304e-01 | 0.024 | 0 | 0 |
| Antigen activates B Cell Receptor (BCR) leading to generation of second messengers | R-HSA-983695 | 9.481315e-01 | 0.023 | 0 | 0 |
| SARS-CoV-2 modulates host translation machinery | R-HSA-9754678 | 9.497129e-01 | 0.022 | 0 | 0 |
| Maturation of TCA enzymes and regulation of TCA cycle | R-HSA-9854311 | 9.509027e-01 | 0.022 | 0 | 0 |
| Tryptophan catabolism | R-HSA-71240 | 9.509027e-01 | 0.022 | 0 | 0 |
| Constitutive Signaling by Aberrant PI3K in Cancer | R-HSA-2219530 | 9.511116e-01 | 0.022 | 0 | 0 |
| Collagen formation | R-HSA-1474290 | 9.511116e-01 | 0.022 | 0 | 0 |
| SHC-mediated cascade:FGFR1 | R-HSA-5654688 | 9.522319e-01 | 0.021 | 0 | 0 |
| Norepinephrine Neurotransmitter Release Cycle | R-HSA-181430 | 9.522319e-01 | 0.021 | 0 | 0 |
| Plasma lipoprotein assembly | R-HSA-8963898 | 9.522319e-01 | 0.021 | 0 | 0 |
| Interleukin-6 family signaling | R-HSA-6783589 | 9.522319e-01 | 0.021 | 0 | 0 |
| Paracetamol ADME | R-HSA-9753281 | 9.533199e-01 | 0.021 | 0 | 0 |
| Peptide hormone metabolism | R-HSA-2980736 | 9.537051e-01 | 0.021 | 0 | 0 |
| Leishmania phagocytosis | R-HSA-9664417 | 9.553119e-01 | 0.020 | 0 | 0 |
| FCGR3A-mediated phagocytosis | R-HSA-9664422 | 9.553119e-01 | 0.020 | 0 | 0 |
| Parasite infection | R-HSA-9664407 | 9.553119e-01 | 0.020 | 0 | 0 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 9.566838e-01 | 0.019 | 0 | 0 |
| PI-3K cascade:FGFR2 | R-HSA-5654695 | 9.568415e-01 | 0.019 | 0 | 0 |
| FRS-mediated FGFR1 signaling | R-HSA-5654693 | 9.568415e-01 | 0.019 | 0 | 0 |
| Hyaluronan degradation | R-HSA-2160916 | 9.568415e-01 | 0.019 | 0 | 0 |
| Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives | R-HSA-9027604 | 9.568415e-01 | 0.019 | 0 | 0 |
| Alpha-oxidation of phytanate | R-HSA-389599 | 9.568415e-01 | 0.019 | 0 | 0 |
| Fertilization | R-HSA-1187000 | 9.568415e-01 | 0.019 | 0 | 0 |
| Metabolism of porphyrins | R-HSA-189445 | 9.580150e-01 | 0.019 | 0 | 0 |
| MyD88:MAL(TIRAP) cascade initiated on plasma membrane | R-HSA-166058 | 9.584689e-01 | 0.018 | 1 | 0 |
| Toll Like Receptor TLR6:TLR2 Cascade | R-HSA-168188 | 9.584689e-01 | 0.018 | 1 | 0 |
| FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | R-HSA-9615017 | 9.585159e-01 | 0.018 | 0 | 0 |
| Protein localization | R-HSA-9609507 | 9.585453e-01 | 0.018 | 0 | 0 |
| Potassium Channels | R-HSA-1296071 | 9.591477e-01 | 0.018 | 0 | 0 |
| Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes | R-HSA-9931510 | 9.610065e-01 | 0.017 | 0 | 0 |
| Glutamate Neurotransmitter Release Cycle | R-HSA-210500 | 9.610065e-01 | 0.017 | 0 | 0 |
| Attachment of bacteria to epithelial cells | R-HSA-9638630 | 9.610065e-01 | 0.017 | 0 | 0 |
| Urea cycle | R-HSA-70635 | 9.610065e-01 | 0.017 | 0 | 0 |
| Synthesis of IP2, IP, and Ins in the cytosol | R-HSA-1855183 | 9.610065e-01 | 0.017 | 0 | 0 |
| Suppression of phagosomal maturation | R-HSA-9637687 | 9.610065e-01 | 0.017 | 0 | 0 |
| Incretin synthesis, secretion, and inactivation | R-HSA-400508 | 9.618847e-01 | 0.017 | 0 | 0 |
| Early SARS-CoV-2 Infection Events | R-HSA-9772572 | 9.627411e-01 | 0.016 | 0 | 0 |
| Regulation of insulin secretion | R-HSA-422356 | 9.638175e-01 | 0.016 | 0 | 0 |
| Signaling by BMP | R-HSA-201451 | 9.647697e-01 | 0.016 | 0 | 0 |
| SHC-mediated cascade:FGFR2 | R-HSA-5654699 | 9.647697e-01 | 0.016 | 0 | 0 |
| Phosphorylation of CD3 and TCR zeta chains | R-HSA-202427 | 9.647697e-01 | 0.016 | 0 | 0 |
| Biosynthesis of DPAn-3 SPMs | R-HSA-9025094 | 9.647697e-01 | 0.016 | 0 | 0 |
| ER Quality Control Compartment (ERQC) | R-HSA-901032 | 9.647697e-01 | 0.016 | 0 | 0 |
| ROS and RNS production in phagocytes | R-HSA-1222556 | 9.658919e-01 | 0.015 | 0 | 0 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 9.678510e-01 | 0.014 | 0 | 0 |
| DAP12 interactions | R-HSA-2172127 | 9.678510e-01 | 0.014 | 0 | 0 |
| RAB geranylgeranylation | R-HSA-8873719 | 9.679944e-01 | 0.014 | 0 | 0 |
| GABA receptor activation | R-HSA-977443 | 9.679944e-01 | 0.014 | 0 | 0 |
| FRS-mediated FGFR2 signaling | R-HSA-5654700 | 9.681700e-01 | 0.014 | 0 | 0 |
| ATF4 activates genes in response to endoplasmic reticulum stress | R-HSA-380994 | 9.681700e-01 | 0.014 | 0 | 0 |
| Pyrimidine salvage | R-HSA-73614 | 9.681700e-01 | 0.014 | 0 | 0 |
| Prednisone ADME | R-HSA-9757110 | 9.681700e-01 | 0.014 | 0 | 0 |
| Pyroptosis | R-HSA-5620971 | 9.681700e-01 | 0.014 | 0 | 0 |
| Biosynthesis of EPA-derived SPMs | R-HSA-9018679 | 9.712423e-01 | 0.013 | 0 | 0 |
| Cell recruitment (pro-inflammatory response) | R-HSA-9664424 | 9.729124e-01 | 0.012 | 0 | 0 |
| Purinergic signaling in leishmaniasis infection | R-HSA-9660826 | 9.729124e-01 | 0.012 | 0 | 0 |
| Regulation of pyruvate metabolism | R-HSA-9861718 | 9.729124e-01 | 0.012 | 0 | 0 |
| Neurotransmitter clearance | R-HSA-112311 | 9.740182e-01 | 0.011 | 0 | 0 |
| Biosynthesis of DPA-derived SPMs | R-HSA-9018683 | 9.765263e-01 | 0.010 | 0 | 0 |
| Molecules associated with elastic fibres | R-HSA-2129379 | 9.765263e-01 | 0.010 | 0 | 0 |
| Synthesis of glycosylphosphatidylinositol (GPI) | R-HSA-162710 | 9.765263e-01 | 0.010 | 0 | 0 |
| Developmental Cell Lineages of the Exocrine Pancreas | R-HSA-9820448 | 9.772118e-01 | 0.010 | 0 | 0 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 9.784610e-01 | 0.009 | 0 | 0 |
| Innate Immune System | R-HSA-168249 | 9.786410e-01 | 0.009 | 1 | 0 |
| DAG1 glycosylations | R-HSA-8931838 | 9.787924e-01 | 0.009 | 0 | 0 |
| N-glycan trimming in the ER and Calnexin/Calreticulin cycle | R-HSA-532668 | 9.790896e-01 | 0.009 | 0 | 0 |
| Azathioprine ADME | R-HSA-9748787 | 9.808270e-01 | 0.008 | 0 | 0 |
| Diseases associated with glycosylation precursor biosynthesis | R-HSA-5609975 | 9.808399e-01 | 0.008 | 0 | 0 |
| Recycling of bile acids and salts | R-HSA-159418 | 9.808399e-01 | 0.008 | 0 | 0 |
| TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 9.820290e-01 | 0.008 | 0 | 0 |
| Regulation of CDH1 posttranslational processing and trafficking to plasma membrane | R-HSA-9768727 | 9.826898e-01 | 0.008 | 0 | 0 |
| Vitamin B5 (pantothenate) metabolism | R-HSA-199220 | 9.826898e-01 | 0.008 | 0 | 0 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 9.828466e-01 | 0.008 | 0 | 0 |
| Leishmania infection | R-HSA-9658195 | 9.829057e-01 | 0.007 | 0 | 0 |
| Parasitic Infection Pathways | R-HSA-9824443 | 9.829057e-01 | 0.007 | 0 | 0 |
| Hyaluronan metabolism | R-HSA-2142845 | 9.843612e-01 | 0.007 | 0 | 0 |
| NPAS4 regulates expression of target genes | R-HSA-9768919 | 9.843612e-01 | 0.007 | 0 | 0 |
| Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 9.858713e-01 | 0.006 | 0 | 0 |
| HS-GAG biosynthesis | R-HSA-2022928 | 9.872357e-01 | 0.006 | 0 | 0 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 9.872357e-01 | 0.006 | 0 | 0 |
| Interconversion of nucleotide di- and triphosphates | R-HSA-499943 | 9.874587e-01 | 0.005 | 0 | 0 |
| Pyruvate metabolism | R-HSA-70268 | 9.875390e-01 | 0.005 | 0 | 0 |
| Aspirin ADME | R-HSA-9749641 | 9.884206e-01 | 0.005 | 0 | 0 |
| NCAM1 interactions | R-HSA-419037 | 9.884684e-01 | 0.005 | 0 | 0 |
| Lysine catabolism | R-HSA-71064 | 9.884684e-01 | 0.005 | 0 | 0 |
| Metabolism of folate and pterines | R-HSA-196757 | 9.884684e-01 | 0.005 | 0 | 0 |
| Biofilm formation | R-HSA-9931953 | 9.895821e-01 | 0.005 | 0 | 0 |
| Dectin-2 family | R-HSA-5621480 | 9.896149e-01 | 0.005 | 0 | 0 |
| Peroxisomal protein import | R-HSA-9033241 | 9.912989e-01 | 0.004 | 0 | 0 |
| Triglyceride metabolism | R-HSA-8979227 | 9.912989e-01 | 0.004 | 0 | 0 |
| Interleukin-2 family signaling | R-HSA-451927 | 9.914974e-01 | 0.004 | 0 | 0 |
| Nuclear Receptor transcription pathway | R-HSA-383280 | 9.922576e-01 | 0.003 | 0 | 0 |
| Aflatoxin activation and detoxification | R-HSA-5423646 | 9.923187e-01 | 0.003 | 0 | 0 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 9.925207e-01 | 0.003 | 0 | 0 |
| Scavenging by Class A Receptors | R-HSA-3000480 | 9.930607e-01 | 0.003 | 0 | 0 |
| SLC-mediated transport of neurotransmitters | R-HSA-442660 | 9.930607e-01 | 0.003 | 0 | 0 |
| G alpha (q) signalling events | R-HSA-416476 | 9.933041e-01 | 0.003 | 0 | 0 |
| Response of Mtb to phagocytosis | R-HSA-9637690 | 9.943367e-01 | 0.002 | 0 | 0 |
| CD22 mediated BCR regulation | R-HSA-5690714 | 9.944258e-01 | 0.002 | 0 | 0 |
| Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 9.948839e-01 | 0.002 | 0 | 0 |
| tRNA modification in the nucleus and cytosol | R-HSA-6782315 | 9.953405e-01 | 0.002 | 0 | 0 |
| Degradation of cysteine and homocysteine | R-HSA-1614558 | 9.953783e-01 | 0.002 | 0 | 0 |
| Nicotinate metabolism | R-HSA-196807 | 9.957408e-01 | 0.002 | 0 | 0 |
| Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation | R-HSA-163841 | 9.962982e-01 | 0.002 | 0 | 0 |
| Plasma lipoprotein remodeling | R-HSA-8963899 | 9.965928e-01 | 0.001 | 0 | 0 |
| GPCR downstream signalling | R-HSA-388396 | 9.970123e-01 | 0.001 | 0 | 0 |
| ECM proteoglycans | R-HSA-3000178 | 9.970308e-01 | 0.001 | 0 | 0 |
| Leishmania parasite growth and survival | R-HSA-9664433 | 9.971778e-01 | 0.001 | 0 | 0 |
| Anti-inflammatory response favouring Leishmania parasite infection | R-HSA-9662851 | 9.971778e-01 | 0.001 | 0 | 0 |
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 9.973463e-01 | 0.001 | 0 | 0 |
| Citric acid cycle (TCA cycle) | R-HSA-71403 | 9.979345e-01 | 0.001 | 0 | 0 |
| TP53 Regulates Transcription of Cell Death Genes | R-HSA-5633008 | 9.979345e-01 | 0.001 | 0 | 0 |
| Plasma lipoprotein assembly, remodeling, and clearance | R-HSA-174824 | 9.979363e-01 | 0.001 | 0 | 0 |
| Glucuronidation | R-HSA-156588 | 9.981486e-01 | 0.001 | 0 | 0 |
| Bile acid and bile salt metabolism | R-HSA-194068 | 9.983095e-01 | 0.001 | 0 | 0 |
| G alpha (i) signalling events | R-HSA-418594 | 9.983919e-01 | 0.001 | 0 | 0 |
| Cholesterol biosynthesis | R-HSA-191273 | 9.984287e-01 | 0.001 | 0 | 0 |
| SLC-mediated transport of organic anions | R-HSA-9955298 | 9.984287e-01 | 0.001 | 0 | 0 |
| Interleukin-10 signaling | R-HSA-6783783 | 9.984287e-01 | 0.001 | 0 | 0 |
| Metabolism of amine-derived hormones | R-HSA-209776 | 9.984893e-01 | 0.001 | 0 | 0 |
| FCERI mediated MAPK activation | R-HSA-2871796 | 9.985582e-01 | 0.001 | 0 | 0 |
| FCGR3A-mediated IL10 synthesis | R-HSA-9664323 | 9.985823e-01 | 0.001 | 0 | 0 |
| Synthesis of PA | R-HSA-1483166 | 9.986354e-01 | 0.001 | 0 | 0 |
| Role of LAT2/NTAL/LAB on calcium mobilization | R-HSA-2730905 | 9.986472e-01 | 0.001 | 0 | 0 |
| Biosynthesis of DHA-derived SPMs | R-HSA-9018677 | 9.988059e-01 | 0.001 | 0 | 0 |
| Mitochondrial translation initiation | R-HSA-5368286 | 9.988587e-01 | 0.000 | 0 | 0 |
| Heparan sulfate/heparin (HS-GAG) metabolism | R-HSA-1638091 | 9.988865e-01 | 0.000 | 0 | 0 |
| Synthesis of bile acids and bile salts | R-HSA-192105 | 9.989519e-01 | 0.000 | 0 | 0 |
| FCERI mediated Ca+2 mobilization | R-HSA-2871809 | 9.990342e-01 | 0.000 | 0 | 0 |
| Nucleotide salvage | R-HSA-8956321 | 9.990915e-01 | 0.000 | 0 | 0 |
| Collagen degradation | R-HSA-1442490 | 9.990915e-01 | 0.000 | 0 | 0 |
| Complex I biogenesis | R-HSA-6799198 | 9.992587e-01 | 0.000 | 0 | 0 |
| Xenobiotics | R-HSA-211981 | 9.993305e-01 | 0.000 | 0 | 0 |
| Metabolism of carbohydrates and carbohydrate derivatives | R-HSA-71387 | 9.994497e-01 | 0.000 | 0 | 0 |
| Collagen biosynthesis and modifying enzymes | R-HSA-1650814 | 9.995543e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid catabolism | R-HSA-9840310 | 9.996364e-01 | 0.000 | 0 | 0 |
| Fatty acyl-CoA biosynthesis | R-HSA-75105 | 9.996364e-01 | 0.000 | 0 | 0 |
| Keratinization | R-HSA-6805567 | 9.997025e-01 | 0.000 | 0 | 0 |
| Purine catabolism | R-HSA-74259 | 9.997034e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation elongation | R-HSA-5389840 | 9.997743e-01 | 0.000 | 0 | 0 |
| Transport of small molecules | R-HSA-382551 | 9.998183e-01 | 0.000 | 0 | 0 |
| Developmental Lineage of Pancreatic Acinar Cells | R-HSA-9925561 | 9.998546e-01 | 0.000 | 0 | 0 |
| Signaling by GPCR | R-HSA-372790 | 9.998615e-01 | 0.000 | 0 | 0 |
| Mitochondrial ribosome-associated quality control | R-HSA-9937383 | 9.998828e-01 | 0.000 | 0 | 0 |
| Phospholipid metabolism | R-HSA-1483257 | 9.998842e-01 | 0.000 | 0 | 0 |
| Metabolism of nucleotides | R-HSA-15869 | 9.998910e-01 | 0.000 | 0 | 0 |
| Post-translational modification: synthesis of GPI-anchored proteins | R-HSA-163125 | 9.999029e-01 | 0.000 | 0 | 0 |
| Peroxisomal lipid metabolism | R-HSA-390918 | 9.999126e-01 | 0.000 | 0 | 0 |
| Sulfur amino acid metabolism | R-HSA-1614635 | 9.999356e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation termination | R-HSA-5419276 | 9.999394e-01 | 0.000 | 0 | 0 |
| Class C/3 (Metabotropic glutamate/pheromone receptors) | R-HSA-420499 | 9.999475e-01 | 0.000 | 0 | 0 |
| Visual phototransduction | R-HSA-2187338 | 9.999513e-01 | 0.000 | 0 | 0 |
| Sphingolipid metabolism | R-HSA-428157 | 9.999559e-01 | 0.000 | 0 | 0 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 9.999597e-01 | 0.000 | 0 | 0 |
| Cell surface interactions at the vascular wall | R-HSA-202733 | 9.999670e-01 | 0.000 | 0 | 0 |
| FCGR activation | R-HSA-2029481 | 9.999715e-01 | 0.000 | 0 | 0 |
| Role of phospholipids in phagocytosis | R-HSA-2029485 | 9.999715e-01 | 0.000 | 0 | 0 |
| Mitochondrial translation | R-HSA-5368287 | 9.999799e-01 | 0.000 | 0 | 0 |
| Respiratory electron transport | R-HSA-611105 | 9.999838e-01 | 0.000 | 0 | 0 |
| Metabolism of steroids | R-HSA-8957322 | 9.999938e-01 | 0.000 | 0 | 0 |
| Arachidonate metabolism | R-HSA-2142753 | 9.999948e-01 | 0.000 | 0 | 0 |
| Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 9.999949e-01 | 0.000 | 0 | 0 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 9.999954e-01 | 0.000 | 0 | 0 |
| Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 9.999958e-01 | 0.000 | 0 | 0 |
| Antimicrobial peptides | R-HSA-6803157 | 9.999963e-01 | 0.000 | 0 | 0 |
| Drug ADME | R-HSA-9748784 | 9.999974e-01 | 0.000 | 0 | 0 |
| Peptide ligand-binding receptors | R-HSA-375276 | 9.999985e-01 | 0.000 | 0 | 0 |
| Biosynthesis of specialized proresolving mediators (SPMs) | R-HSA-9018678 | 9.999987e-01 | 0.000 | 0 | 0 |
| Infection with Mycobacterium tuberculosis | R-HSA-9635486 | 9.999989e-01 | 0.000 | 0 | 0 |
| Sensory perception of sweet, bitter, and umami (glutamate) taste | R-HSA-9717207 | 9.999991e-01 | 0.000 | 0 | 0 |
| Glycosphingolipid metabolism | R-HSA-1660662 | 9.999991e-01 | 0.000 | 0 | 0 |
| Binding and Uptake of Ligands by Scavenger Receptors | R-HSA-2173782 | 9.999993e-01 | 0.000 | 0 | 0 |
| Nucleotide catabolism | R-HSA-8956319 | 9.999996e-01 | 0.000 | 0 | 0 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 9.999997e-01 | 0.000 | 0 | 0 |
| Sensory perception of taste | R-HSA-9717189 | 9.999997e-01 | 0.000 | 0 | 0 |
| O-linked glycosylation | R-HSA-5173105 | 9.999998e-01 | 0.000 | 0 | 0 |
| Cytochrome P450 - arranged by substrate type | R-HSA-211897 | 9.999999e-01 | 0.000 | 0 | 0 |
| Metabolism of vitamins and cofactors | R-HSA-196854 | 9.999999e-01 | 0.000 | 0 | 0 |
| Bacterial Infection Pathways | R-HSA-9824439 | 1.000000e+00 | 0.000 | 0 | 0 |
| Aerobic respiration and respiratory electron transport | R-HSA-1428517 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycerophospholipid biosynthesis | R-HSA-1483206 | 1.000000e+00 | 0.000 | 0 | 0 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 1.000000e+00 | 0.000 | 0 | 0 |
| Glycosaminoglycan metabolism | R-HSA-1630316 | 1.000000e+00 | 0.000 | 0 | 0 |
| Infection with Enterobacteria | R-HSA-9640148 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of glycosylation | R-HSA-3781865 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase I - Functionalization of compounds | R-HSA-211945 | 1.000000e+00 | 0.000 | 0 | 0 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 1.000000e+00 | 0.000 | 0 | 0 |
| Phase II - Conjugation of compounds | R-HSA-156580 | 1.000000e+00 | 0.000 | 0 | 0 |
| Fatty acid metabolism | R-HSA-8978868 | 1.000000e+00 | 0.000 | 0 | 0 |
| GPCR ligand binding | R-HSA-500792 | 1.000000e+00 | 0.000 | 0 | 0 |
| Diseases of metabolism | R-HSA-5668914 | 1.000000e+00 | 0.000 | 0 | 0 |
| Olfactory Signaling Pathway | R-HSA-381753 | 1.000000e+00 | -0.000 | 0 | 0 |
| Sensory Perception | R-HSA-9709957 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism of lipids | R-HSA-556833 | 1.000000e+00 | -0.000 | 0 | 0 |
| Metabolism | R-HSA-1430728 | 1.000000e+00 | -0.000 | 0 | 0 |
| Biological oxidations | R-HSA-211859 | 1.000000e+00 | -0.000 | 0 | 0 |
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
