LRRK2
Normalized values from positional scanning peptide array
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
T Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: T Sites / T Background
Sites with acceptor types representing >8% and count ≥10 are included
Motif clusters with count ≥ 10 are shown
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| substrate_uniprot | site | source | substrate_genes | site_seq |
|---|---|---|---|---|
| O00429 | T595 | SIGNOR|PSP | DNM1L DLP1 DRP1 | GGVGDGVQEPTtGNWRGMLKtSKAEELLAEEKsKPIPIMPA |
| O15379 | S424 | PSP | HDAC3 | YSRPEAPNEFYDGDHDNDKEsDVEI________________ |
| O43318 | S439 | Sugiyama | MAP3K7 TAK1 | GNILDVPEIVISGNGQPRRRsIQDLtVtGTEPGQVssRsss |
| O60841 | S107 | Sugiyama | EIF5B IF2 KIAA0741 | NEEEFtsKDKKKKGQKGKKQsFDDNDsEELEDKDsKSKKTA |
| O60841 | S182 | Sugiyama | EIF5B IF2 KIAA0741 | DGsEEDEDNsKKIKERsRINssGEsGDEsDEFLQsRKGQKK |
| O75061 | S570 | EPSD|PSP | DNAJC6 KIAA0473 | PSGPASTQSTPRRsATstsAsPtLRVGEGATFDPFGAPSKP |
| O95295 | T117 | SIGNOR|EPSD|PSP | SNAPIN BLOC1S7 SNAP25BP SNAPAP | NILQNAQERLRRLNHSVAKEtARRRAMLDsGIyPPGsPGK_ |
| O95714 | S2928 | Sugiyama | HERC2 | ILLGRIRAEEEDLAAVPFLAsDNEEEEDEKGNSGsLIRKKA |
| P04637 | T304 | EPSD|PSP | TP53 P53 | tEEENLRKKGEPHHELPPGStKRALPNNTsssPQPKKKPLD |
| P04637 | T377 | EPSD|PSP | TP53 P53 | KEPGGSRAHssHLKsKKGQstsRHKKLMFKtEGPDsD____ |
| P04792 | S82 | Sugiyama | HSPB1 HSP27 HSP28 | AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN |
| P05067 | T743 | EPSD|PSP | APP A4 AD1 | LKKKQYtsIHHGVVEVDAAVtPEERHLSKMQQNGyENPtyK |
| P08238 | S462 | Sugiyama | HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB | HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs |
| P10412 | S36 | Sugiyama | H1-4 H1F4 HIST1H1E | EKtPVKKKARKsAGAAKRKAsGPPVsELItKAVAASKERsG |
| P13861 | S99 | Sugiyama | PRKAR2A PKR2 PRKAR2 | EsEEDEDLEVPVPsRFNRRVsVCAEtyNPDEEEEDTDPRVI |
| P15311 | T567 | EPSD|PSP | EZR VIL2 | RTHNDIIHNENMRQGRDKYKtLRQIRQGNTKQRIDEFEAL_ |
| P16402 | S37 | Sugiyama | H1-3 H1F3 HIST1H1D | KtPVKKKAKKAGATAGKRKAsGPPVsELItKAVAASKERsG |
| P16403 | S36 | Sugiyama | H1-2 H1F2 HIST1H1C | EKAPVKKKAAKKAGGtPRKAsGPPVsELItKAVAASKERsG |
| P26038 | T558 | GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP | MSN | KTANDMIHAENMRLGRDKYKtLRQIRQGNTKQRIDEFEsM_ |
| P26373 | S77 | Sugiyama | RPL13 BBC1 OK/SW-cl.46 | PIVRCPTVRYHTKVRAGRGFsLEELRVAGIHKKVARTIGIs |
| P30048 | T146 | SIGNOR | PRDX3 AOP1 | NCEVVAVSVDSHFSHLAWINtPRKNGGLGHMNIALLSDLTK |
| P30533 | S242 | Sugiyama | LRPAP1 A2MRAP | TELKEKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWD |
| P31749 | S473 | SIGNOR|EPSD|PSP | AKT1 PKB RAC | DQDDSMECVDSERRPHFPQFsysAsGtA_____________ |
| P35241 | T564 | EPSD|PSP | RDX | KTQNDVLHAENVKAGRDKYKtLRQIRQGNtKQRIDEFEAM_ |
| P37840 | S129 | SIGNOR | SNCA NACP PARK1 | QEGILEDMPVDPDNEAyEMPsEEGyQDyEPEA_________ |
| P43243 | S188 | Sugiyama | MATR3 KIAA0723 | EPPyRVPRDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRs |
| P43243 | S195 | Sugiyama | MATR3 KIAA0723 | RDDWEEKRHFRRDsFDDRGPsLNPVLDyDHGsRsQEsGyyD |
| P43487 | S60 | Sugiyama | RANBP1 | TLEEDEEELFKMRAKLFRFAsENDLPEWKERGTGDVKLLKH |
| P46459 | T645 | SIGNOR|EPSD|PSP | NSF | ALLVLLKKAPPQGRKLLIIGtTSRKDVLQEMEMLNAFSTTI |
| P60709 | S199 | Sugiyama | ACTB | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P61006 | T72 | GPS6|SIGNOR|PSP | RAB8A MEL RAB8 | LDGKRIKLQIWDtAGQERFRtITTAYYRGAMGIMLVYDITN |
| P61020 | T6 | SIGNOR|EPSD|PSP | RAB5B | _______________MTSRstARPNGQPQASKICQFKLVLL |
| P61026 | T73 | SIGNOR|PSP | RAB10 | LQGKKIKLQIWDtAGQERFHtIttsYYRGAMGIMLVYDITN |
| P62280 | T28 | EPSD|PSP | RPS11 | RAyQKQPtIFQNKKRVLLGEtGKEKLPRYYKNIGLGFKtPK |
| P62280 | T46 | EPSD|PSP | RPS11 | GEtGKEKLPRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNV |
| P62280 | T54 | EPSD|PSP | RPS11 | PRYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILs |
| P62841 | T136 | EPSD|PSP | RPS15 RIG | LGEFSITYKPVKHGRPGIGAtHsSRFIPLK___________ |
| P62906 | S64 | Sugiyama | RPL10A NEDD6 | QKDKRFsGTVRLKSTPRPKFsVCVLGDQQHCDEAKAVDIPH |
| P62937 | T157 | Sugiyama | PPIA CYPA | NIVEAMERFGsRNGKTSKKItIADCGQLE____________ |
| P63261 | S199 | Sugiyama | ACTG1 ACTG | DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV |
| P67809 | S102 | Sugiyama | YBX1 NSEP1 YB1 | EDVFVHQtAIKKNNPRKyLRsVGDGEtVEFDVVEGEKGAEA |
| Q08J23 | S593 | Sugiyama | NSUN2 SAKI TRM4 | NNSEKMKVINTGIKVWCRNNsGEEFDCAFRLAQEGIYTLYP |
| Q09161 | S22 | Sugiyama | NCBP1 CBP80 NCBP | SRRRHsDENDGGQPHKRRKtsDANEtEDHLEsLICKVGEKS |
| Q12982 | S114 | Sugiyama | BNIP2 NIP2 | EFEWEDDLPKPKTTEVIRKGsItEyTAAEEKEDGRRWRMFR |
| Q13428 | S87 | Sugiyama | TCOF1 | EDAALQAKKTRVsDPIstsEssEEEEEAEAETAKAtPRLAs |
| Q13501 | T138 | EPSD|PSP | SQSTM1 ORCA OSIL | PRNMVHPNVICDGCNGPVVGtRYKCSVCPDyDLCsVCEGKG |
| Q14155 | T127 | SIGNOR | ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314 | FDANDLYQGQNFNKVLSSLVtLNKVTADIGLGSDsVCARPs |
| Q14155 | T164 | SIGNOR | ARHGEF7 COOL1 KIAA0142 P85SPR PAK3BP PIXB Nbla10314 | ARPssHRIKsFDsLGsQsLHtRtsKLFQGQYRsLDMTDNSN |
| Q14671 | S709 | Sugiyama | PUM1 KIAA0099 PUMH1 | LGGFGTAVANSNTGSGSRRDsLtGSsDLYKRTSSSLTPIGH |
| Q3KQU3 | S112 | Sugiyama | MAP7D1 KIAA1187 PARCC1 RPRC1 PP2464 | KsRGPtPPAMGPRDARPPRRssQPsPtAVPAsDsPPtKQEV |
| Q5S007 | S1124 | EPSD|PSP | LRRK2 PARK8 | DVVEKLEQLILEGNKISGICsPLRLKELKILNLSKNHISSL |
| Q5S007 | S1253 | EPSD|PSP | LRRK2 PARK8 | SILDLSEKAYLWSRVEKLHLsHNKLKEIPPEIGCLENLTSL |
| Q5S007 | S1283 | EPSD|PSP | LRRK2 PARK8 | EIGCLENLTSLDVSYNLELRsFPNEMGKLsKIWDLPLDELH |
| Q5S007 | S1292 | EPSD|PSP | LRRK2 PARK8 | SLDVSYNLELRsFPNEMGKLsKIWDLPLDELHLNFDFKHIG |
| Q5S007 | S1345 | EPSD|PSP | LRRK2 PARK8 | RLKKAVPyNRMKLMIVGNtGsGKtTLLQQLMKtKKSDLGMQ |
| Q5S007 | S1403 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | KRKRDLVLNVWDFAGREEFystHPHFMtQRALYLAVYDLSK |
| Q5S007 | S1443 | EPSD|PSP | LRRK2 PARK8 | KGQAEVDAMKPWLFNIKARAsssPVILVGtHLDVsDEKQRK |
| Q5S007 | S1444 | EPSD|PSP | LRRK2 PARK8 | GQAEVDAMKPWLFNIKARAsssPVILVGtHLDVsDEKQRKA |
| Q5S007 | S1445 | EPSD|PSP|Sugiyama | LRRK2 PARK8 | QAEVDAMKPWLFNIKARAsssPVILVGtHLDVsDEKQRKAC |
| Q5S007 | S1457 | EPSD|PSP | LRRK2 PARK8 | NIKARAsssPVILVGtHLDVsDEKQRKACMsKItKELLNKR |
| Q5S007 | S1467 | EPSD|PSP | LRRK2 PARK8 | VILVGtHLDVsDEKQRKACMsKItKELLNKRGFPAIRDyHF |
| Q5S007 | S1508 | EPSD|PSP | LRRK2 PARK8 | VNAtEESDALAKLRKtIINEsLNFKIRDQLVVGQLIPDCYV |
| Q5S007 | S1536 | EPSD|PSP | LRRK2 PARK8 | QLVVGQLIPDCYVELEKIILsERKNVPIEFPVIDRKRLLQL |
| Q5S007 | S1647 | EPSD|PSP | LRRK2 PARK8 | sRRDVEKFLSKKRKFPKNYMsQYFKLLEKFQIALPIGEEYL |
| Q5S007 | S1853 | EPSD|PSP | LRRK2 PARK8 | KAEEGDLLVNPDQPRLtIPIsQIAPDLILADLPRNIMLNND |
| Q5S007 | S1913 | EPSD|PSP | LRRK2 PARK8 | VYRAAYEGEEVAVKIFNKHtsLRLLRQELVVLCHLHHPSLI |
| Q5S007 | S2032 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | IAKIADyGIAQYCCRMGIKtsEGtPGFRAPEVARGNVIYNQ |
| Q5S007 | S2166 | Sugiyama | LRRK2 PARK8 | LPKNVIVECMVATHHNSRNAsIWLGCGHTDRGQLSFLDLNT |
| Q5S007 | S2257 | EPSD|PSP | LRRK2 PARK8 | TLEKMTDSVTCLYCNSFSKQsKQKNFLLVGTADGKLAIFED |
| Q5S007 | S2370 | Sugiyama | LRRK2 PARK8 | SDSNIITVVVDTALYIAKQNsPVVEVWDKKTEKLCGLIDCV |
| Q5S007 | S3 | EPSD|PSP | LRRK2 PARK8 | __________________MAsGsCQGCEEDEETLKKLIVRL |
| Q5S007 | S5 | EPSD|PSP | LRRK2 PARK8 | ________________MAsGsCQGCEEDEETLKKLIVRLNN |
| Q5S007 | S910 | PSP | LRRK2 PARK8 | SDDLDSEGSEGSFLVKKKsNsISVGEFYRDAVLQRCsPNLQ |
| Q5S007 | S935 | PSP | LRRK2 PARK8 | EFYRDAVLQRCsPNLQRHsNsLGPIFDHEDLLKRKRKILSs |
| Q5S007 | S955 | PSP | LRRK2 PARK8 | sLGPIFDHEDLLKRKRKILSsDDSLRSSKLQSHMRHsDsIs |
| Q5S007 | S971 | Sugiyama | LRRK2 PARK8 | KILSsDDSLRSSKLQSHMRHsDsIssLASEREYITSLDLSA |
| Q5S007 | S973 | PSP|Sugiyama | LRRK2 PARK8 | LSsDDSLRSSKLQSHMRHsDsIssLASEREYITSLDLSANE |
| Q5S007 | S975 | Sugiyama | LRRK2 PARK8 | sDDSLRSSKLQSHMRHsDsIssLASEREYITSLDLSANELR |
| Q5S007 | S976 | Sugiyama | LRRK2 PARK8 | DDSLRSSKLQSHMRHsDsIssLASEREYITSLDLSANELRD |
| Q5S007 | T1343 | EPSD|PSP | LRRK2 PARK8 | QQRLKKAVPyNRMKLMIVGNtGsGKtTLLQQLMKtKKSDLG |
| Q5S007 | T1348 | EPSD|PSP | LRRK2 PARK8 | KAVPyNRMKLMIVGNtGsGKtTLLQQLMKtKKSDLGMQSAt |
| Q5S007 | T1357 | EPSD|PSP | LRRK2 PARK8 | LMIVGNtGsGKtTLLQQLMKtKKSDLGMQSAtVGIDVKDWP |
| Q5S007 | T1368 | EPSD|PSP | LRRK2 PARK8 | tTLLQQLMKtKKSDLGMQSAtVGIDVKDWPIQIRDKRKRDL |
| Q5S007 | T1404 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | RKRDLVLNVWDFAGREEFystHPHFMtQRALYLAVYDLSKG |
| Q5S007 | T1410 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | LNVWDFAGREEFystHPHFMtQRALYLAVYDLSKGQAEVDA |
| Q5S007 | T1452 | EPSD|PSP | LRRK2 PARK8 | KPWLFNIKARAsssPVILVGtHLDVsDEKQRKACMsKItKE |
| Q5S007 | T1470 | EPSD|PSP | LRRK2 PARK8 | VGtHLDVsDEKQRKACMsKItKELLNKRGFPAIRDyHFVNA |
| Q5S007 | T1491 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | KELLNKRGFPAIRDyHFVNAtEESDALAKLRKtIINEsLNF |
| Q5S007 | T1503 | EPSD|PSP | LRRK2 PARK8 | RDyHFVNAtEESDALAKLRKtIINEsLNFKIRDQLVVGQLI |
| Q5S007 | T1612 | EPSD|PSP | LRRK2 PARK8 | LSDLYFVEPKWLCKIMAQILtVKVEGCPKHPKGIIsRRDVE |
| Q5S007 | T1849 | EPSD|PSP | LRRK2 PARK8 | DLMKKAEEGDLLVNPDQPRLtIPIsQIAPDLILADLPRNIM |
| Q5S007 | T1912 | EPSD|PSP | LRRK2 PARK8 | SVYRAAYEGEEVAVKIFNKHtsLRLLRQELVVLCHLHHPSL |
| Q5S007 | T1967 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | MELASKGSLDRLLQQDKASLtRtLQHRIALHVADGLRYLHS |
| Q5S007 | T1969 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | LASKGSLDRLLQQDKASLtRtLQHRIALHVADGLRYLHSAM |
| Q5S007 | T2031 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | IIAKIADyGIAQYCCRMGIKtsEGtPGFRAPEVARGNVIYN |
| Q5S007 | T2035 | SIGNOR|EPSD|PSP | LRRK2 PARK8 | IADyGIAQYCCRMGIKtsEGtPGFRAPEVARGNVIYNQQAD |
| Q5S007 | T2483 | EPSD|PSP | LRRK2 PARK8 | LGSLKNVMLVLGYNRKNTEGtQKQKEIQSCLTVWDINLPHE |
| Q5S007 | T2524 | EPSD|PSP | LRRK2 PARK8 | VQNLEKHIEVRKELAEKMRRtSVE_________________ |
| Q5S007 | T424 | EPSD|PSP | LRRK2 PARK8 | SMLMHSSSKEVFQASANALStLLEQNVNFRKILLSKGIHLN |
| Q5S007 | T524 | EPSD|PSP | LRRK2 PARK8 | ALRAILHFIVPGMPEESREDtEFHHKLNMVKKQCFKNDIHK |
| Q5S007 | T776 | EPSD|PSP | LRRK2 PARK8 | KLVELLLNSGSREQDVRKALtISIGKGDSQIISLLLRRLAL |
| Q5S007 | T826 | EPSD|PSP | LRRK2 PARK8 | GGFCIGKVEPSWLGPLFPDKtSNLRKQtNIAStLARMVIRY |
| Q5S007 | T833 | EPSD|PSP | LRRK2 PARK8 | VEPSWLGPLFPDKtSNLRKQtNIAStLARMVIRYQMKSAVE |
| Q5S007 | T838 | EPSD|PSP | LRRK2 PARK8 | LGPLFPDKtSNLRKQtNIAStLARMVIRYQMKSAVEEGTAS |
| Q5S007 | Y1332 | EPSD|PSP | LRRK2 PARK8 | GCKAKDIIRFLQQRLKKAVPyNRMKLMIVGNtGsGKtTLLQ |
| Q5S007 | Y1402 | EPSD|PSP | LRRK2 PARK8 | DKRKRDLVLNVWDFAGREEFystHPHFMtQRALYLAVYDLS |
| Q5S007 | Y1485 | EPSD|PSP | LRRK2 PARK8 | CMsKItKELLNKRGFPAIRDyHFVNAtEESDALAKLRKtII |
| Q5T0N5 | S488 | Sugiyama | FNBP1L C1orf39 TOCA1 | NEAWLSEVEGKTGGRGDRRHssDINHLVtQGREsPEGsytD |
| Q5T0N5 | S489 | Sugiyama | FNBP1L C1orf39 TOCA1 | EAWLSEVEGKTGGRGDRRHssDINHLVtQGREsPEGsytDD |
| Q6GYQ0 | S860 | Sugiyama | RALGAPA1 GARNL1 KIAA0884 TULIP1 | DEFIAERLRSGNASTMTRRGssPGsLEIPKDLPDILNKQNQ |
| Q6ZN18 | S206 | Sugiyama | AEBP2 | DEGYGTGGGGSSATSGGRRGsLEMssDGEPLSRMDSEDSIS |
| Q6ZVN8 | T290 | Sugiyama | HJV HFE2 RGMC | PGNHVEIQAAYIGTTIIIRQtAGQLSFSIKVAEDVAMAFSA |
| Q7Z417 | S652 | Sugiyama | NUFIP2 KIAA1321 PIG1 | NtLLGsAKEQRYQRGLERNDsWGsFDLRAAIVYHTKEMEsI |
| Q86VQ1 | S223 | Sugiyama | GLCCI1 | QTPsCWAEEGAEKRSHQRsAsWGsADQLKEQIAKLRQQLQR |
| Q8NFD5 | S1744 | Sugiyama | ARID1B BAF250B DAN15 KIAA1235 OSA2 | ALDTINILLYDDSTVATFNLsQLSGFLELLVEYFRKCLIDI |
| Q8TE77 | S37 | Sugiyama | SSH3 SSH3L | tPVGPWDQAVQRRSRLQRRQsFAVLRGAVLGLQDGGDNDDA |
| Q96CW1 | T156 | PSP | AP2M1 CLAPM1 KIAA0109 | QGIKSQHQTKEEQSQItsQVtGQIGWRREGIKYRRNELFLD |
| Q96G46 | T240 | Sugiyama | DUS3L | KREVRFERAEQALRRFsQGPtPAAAVPEGTAAEGAPRQENC |
| Q96RU3 | S497 | Sugiyama | FNBP1 FBP17 KIAA0554 | AWLAEVEGRLPARSEQARRQsGLyDSQNPPTVNNCAQDREs |
| Q99683 | T825 | SIGNOR|EPSD|PSP | MAP3K5 ASK1 MAPKKK5 MEKK5 | KGDNVLINtYSGVLKISDFGtSKRLAGINPCTEtFTGtLQy |
| Q99683 | T838 | EPSD|PSP | MAP3K5 ASK1 MAPKKK5 MEKK5 | LKISDFGtSKRLAGINPCTEtFTGtLQyMAPEIIDKGPRGY |
| Q99962 | S75 | SIGNOR | SH3GL2 CNSA2 SH3D2A | IEyLQPNPAsRAKLSMINTMsKIRGQEKGPGYPQAEALLAE |
| Q9BTC0 | S1456 | Sugiyama | DIDO1 C20orf158 DATF1 KIAA0333 | EAKVTVDDLPNRMCADVRRNsVERPAEPVAGAAtPsLVEQQ |
| Q9BW61 | S33 | Sugiyama | DDA1 C19orf58 PCIA1 | KSNFSRFHADSVCKASNRRPsVYLPTREYPSEQIIVTEKTN |
| Q9BX95 | T114 | Sugiyama | SGPP1 SPP1 | AAELGPAsPRRAGALRRNsLtGEEGQLARVSNWPLYCLFCF |
| Q9C0C2 | S429 | Sugiyama | TNKS1BP1 KIAA1741 TAB182 | EEEAKGDAHLRPtsLVQRRFsEGVLQsPsQDQEKLGGsLAA |
| Q9NPG1 | T598 | PSP | FZD3 | IHSKVSSYHGSLHRSRDGRYtPCSYRGMEERLPHGSMSRLT |
| Q9NSY1 | S1029 | Sugiyama | BMP2K BIKE HRIHFB2017 | KPTYRtPERARRHKKVGRRDsQssNEFLTIsDSKENISVAL |
| Q9P2J5 | T293 | SIGNOR|PSP | LARS1 KIAA1352 LARS | EPYPSKLSGLKGKNIFLVAAtLRPETMFGQTNCWVRPDMKY |
| Q9ULL1 | S615 | Sugiyama | PLEKHG1 KIAA1209 | STETSSSGHRIVRRAssAGEsNtCPPEIGTSDRTRELQNSP |
| Q9UQ35 | S1539 | Sugiyama | SRRM2 KIAA0324 SRL300 SRM300 HSPC075 | sEssVDQKtVARtPLGQRsRsGssQELDVKPsAsPQERsEs |
| Q9Y2I7 | S307 | Sugiyama | PIKFYVE KIAA0981 PIP5K3 | TRLVSVQEDAGKsPARNRsAsItNLsLDRsGsPMVPSYEts |
Site Promiscuity
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