LIMK1

TYR version of PSPA with Y as phospho-acceptor
Phospho-serine (pS) is a duplicate of phospho-tyrosine (pT) in PSPA
Position-wise Probabilities
Log-Odds: Probabilities / STY Background
Sites with acceptor types representing >8% and count ≥10 are included
S Sites Probabilities
Y Sites Probabilities
Log-Odds: S Sites / S Background
Log-Odds: Y Sites / Y Background
Sites with acceptor types representing >8% and count ≥10 are included
Download Data Table
Motif clusters with count ≥ 10 are shown
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substrate_uniprot site source substrate_genes site_seq
A5A3E0 S1065 Sugiyama POTEF A26C1B ILASLSTFQQMWISKQEyDEsGPsIVHRKCL__________
A5A3E0 S1068 Sugiyama POTEF A26C1B SLSTFQQMWISKQEyDEsGPsIVHRKCL_____________
A5A3E0 Y1062 Sugiyama POTEF A26C1B GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCL_______
A5A3E0 Y940 Sugiyama POTEF A26C1B ALDFEQEMATVAsSSSLEKsyELPDGQVItIGNERFRCPEA
A6NMY6 S164 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGS
A6NMY6 Y333 Sugiyama ANXA2P2 ANX2L2 ANX2P2 LPC2B KsLyyyIQQDTKGDyQKALLyLCGGDD______________
O00410 S974 Sugiyama IPO5 KPNB3 RANBP5 VIQSADSKTKENVNAtENCIsAVGKIMKFKPDCVNVEEVLP
O14579 Y304 Sugiyama COPE HPFIKEYQAKENDFDRLVLQyAPsA________________
O14744 Y502 Sugiyama PRMT5 HRMT1L5 IBP72 JBP1 SKB1 NEVRACREKDRDPEAQFEMPyVVRLHNFHQLSAPQPCFTFS
O14950 Y156 Sugiyama MYL12B MRLC2 MYLC2B DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
O14974 S695 Sugiyama PPP1R12A MBS MYPT1 DEEsEsQRKARSRQARQsRRstQGVtLtDLQEAEKtIGRSR
O15357 Y190 Sugiyama INPPL1 SHIP2 AAESAPNGLSTVSHDYLKGsyGLDLEAVRGGASHLPHLTRT
O15371 Y50 Sugiyama EIF3D EIF3S7 yQPFsKGDRLGKVADWtGAtyQDKRYTNKYSSQFGGGSQYA
O15460 Y249 Sugiyama P4HA2 UNQ290/PRO330 LTRRLLSLDPSHERAGGNLRyFEQLLEEEREKTLTNQTEAE
O43390 Y136 Sugiyama HNRNPR HNRPR QESTKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O43423 S100 Sugiyama ANP32CP PP32R1 AEKCPNLTHLYLSGNKIKDLstIEPLKQLENLKSLDLFNCE
O43448 Y311 Sugiyama KCNAB3 KCNA3B LITSKYDGRVPDTCRASIKGyQWLKDKVQSEDGKKQQAKVM
O43707 Y397 Sugiyama ACTN4 GKMVSDINNGWQHLEQAEKGyEEWLLNEIRRLERLDHLAEK
O43707 Y878 Sugiyama ACTN4 DKNFITAEELRRELPPDQAEyCIARMAPyQGPDAVPGALDy
O43765 Y141 Sugiyama SGTA SGT SGT1 NPANAVYFCNRAAAYSKLGNyAGAVQDCERAICIDPAySKA
O43852 S261 Sugiyama CALU RDKNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNK
O43852 Y263 Sugiyama CALU KNRDGKMDKEEtKDWILPsDyDHAEAEARHLVyEsDQNKDG
O60361 Y136 Sugiyama NME2P1 SLRFKPEELVDYKSCAHDWVyE___________________
O60506 Y133 Sugiyama SYNCRIP HNRPQ NSAP1 ADSSKGPDEAKIKALLERtGytLDVttGQRKYGGPPPDSVY
O60664 Y95 Sugiyama PLIN3 M6PRBP1 TIP47 VsGAQPILSKLEPQIAsAsEyAHRGLDKLEENLPILQQPTE
O60814 Y41 Sugiyama H2BC12 H2BFT HIRIP1 HIST1H2BK KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
O75369 T907 Sugiyama FLNB FLN1L FLN3 TABP TAP PLPGDAVKDLDIIDNyDysHtVKYtPtQQGNMQVLVTYGGD
O75390 Y345 Sugiyama CS DEKLRDYIWNtLNSGRVVPGyGHAVLRKTDPRYTCQREFAL
O75475 Y18 Sugiyama PSIP1 DFS70 LEDGF PSIP2 ___MTRDFKPGDLIFAKMKGyPHWPARVDEVPDGAVKPPTN
O75534 S766 Sugiyama CSDE1 D1S155E KIAA0885 NRU UNR AAPRPDRLVNRLKNItLDDAsAPRLMVLRQPRGPDNsMGFG
O75683 Y10 Sugiyama SURF6 SURF-6 ___________MASLLAKDAyLQsLAKKICSHsAPEQQART
O95626 S104 Sugiyama ANP32D PP32R2 AEKCPNLIHLNLSGNKIKDLstIEPLKKLENLESLDLFTCE
P00338 S161 Sugiyama LDHA PIG19 DILTYVAWKISGFPKNRVIGsGCNLDsARFRyLMGERLGVH
P00338 Y10 Sugiyama LDHA PIG19 ___________MAtLKDQLIyNLLKEEQtPQNKITVVGVGA
P00338 Y172 Sugiyama LDHA PIG19 GFPKNRVIGsGCNLDsARFRyLMGERLGVHPLSCHGWVLGE
P00338 Y239 Sugiyama LDHA PIG19 GtDKDKEQWKEVHKQVVEsAyEVIKLKGYtSWAIGLSVADL
P00491 Y166 Sugiyama PNP NP PLRGPNDERFGDRFPAMsDAyDRtMRQRALstWKQMGEQRE
P00505 Y179 Sugiyama GOT2 KYAT4 KPTWGNHtPIFRDAGMQLQGyRYYDPKtCGFDFtGAVEDIS
P00558 Y161 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 KAEPAKIEAFRAsLSKLGDVyVNDAFGtAHRAHssMVGVNL
P00558 Y196 Sugiyama PGK1 PGKA MIG10 OK/SW-cl.110 MVGVNLPQKAGGFLMKKELNyFAKALEsPERPFLAILGGAK
P00966 Y163 Sugiyama ASS1 ASS APWRMPEFYNRFKGRNDLMEyAKQHGIPIPVtPKNPWSMDE
P04075 S336 Sugiyama ALDOA ALDA GKKENLKAAQEEYVKRALANsLACQGKytPsGQAGAAAsEs
P04075 S36 Sugiyama ALDOA ALDA LsDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENR
P04075 S39 Sugiyama ALDOA ALDA IAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRRFy
P04075 S46 Sugiyama ALDOA ALDA PGKGILAADEstGsIAKRLQsIGtENtEENRRFyRQLLLtA
P04075 T37 Sugiyama ALDOA ALDA sDIAHRIVAPGKGILAADEstGsIAKRLQsIGtENtEENRR
P04083 S201 Sugiyama ANXA1 ANX1 LPC1 LsLAKGDRsEDFGVNEDLADsDARALyEAGERRKGtDVNVF
P04406 S241 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 IPELNGKLtGMAFRVPtANVsVVDLtCRLEKPAKyDDIKKV
P04406 Y314 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 tFDAGAGIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsK
P04406 Y320 Sugiyama GAPDH GAPD CDABP0047 OK/SW-cl.12 GIALNDHFVKLIsWyDNEFGysNRVVDLMAHMAsKE_____
P04792 S82 Sugiyama HSPB1 HSP27 HSP28 AIEsPAVAAPAYsRALsRQLssGVsEIRHtADRWRVsLDVN
P05362 Y455 Sugiyama ICAM1 GtFPLPIGEsVtVtRDLEGtyLCRARSTQGEVTRKVTVNVL
P05386 S101 Sugiyama RPLP1 RRP1 APstAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD_______
P05386 S104 Sugiyama RPLP1 RRP1 tAAAPAEEKKVEAKKEEsEEsDDDMGFGLFD__________
P05387 S102 Sugiyama RPLP2 D11S2243E RPP2 PAAGsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD_______
P05387 S105 Sugiyama RPLP2 D11S2243E RPP2 GsAPAAAEEKKDEKKEEsEEsDDDMGFGLFD__________
P05388 S307 Sugiyama RPLP0 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
P05787 Y282 Sugiyama KRT8 CYK8 EVKAQyEDIANRsRAEAEsMyQIKyEELQsLAGKHGDDLRR
P06730 Y197 Sugiyama EIF4E EIF4EL1 EIF4F THIGRVYKERLGLPPKIVIGyQsHADTAtKsGsttKNRFVV
P06733 S27 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 HAREIFDsRGNPtVEVDLFtsKGLFRAAVPsGAstGIyEAL
P06733 S349 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 AKAVNEKsCNCLLLKVNQIGsVTEsLQACKLAQANGWGVMV
P06733 S419 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 CRSERLAKyNQLLRIEEELGsKAKFAGRNFRNPLAK_____
P06733 Y189 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 MILPVGAANFREAMRIGAEVyHNLKNVIKEKyGKDAtNVGD
P06733 Y257 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 TDKVVIGMDVAASEFFRsGKyDLDFKsPDDPsRyIsPDQLA
P06733 Y270 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 EFFRsGKyDLDFKsPDDPsRyIsPDQLADLyKsFIKDyPVV
P06733 Y280 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 DFKsPDDPsRyIsPDQLADLyKsFIKDyPVVsIEDPFDQDD
P06733 Y407 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 GLCtGQIKTGAPCRSERLAKyNQLLRIEEELGsKAKFAGRN
P06733 Y44 Sugiyama ENO1 ENO1L1 MBPB1 MPB1 LFtsKGLFRAAVPsGAstGIyEALELRDNDKtRYMGKGVSK
P06744 Y351 Sugiyama GPI FGCETHAMLPYDQYLHRFAAyFQQGDMEsNGKYITKSGtRV
P07195 S162 Sugiyama LDHB DILTYVTWKLSGLPKHRVIGsGCNLDsARFRyLMAEKLGIH
P07195 S303 Sugiyama LDHB GIENEVFLSLPCILNARGLtsVINQKLKDDEVAQLKKsADt
P07205 Y161 Sugiyama PGK2 PGKB KAEPDKIEAFRAsLSKLGDVyVNDAFGtAHRAHSSMVGVNL
P07237 Y327 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB LKKEECPAVRLITLEEEMTKyKPEsEELtAERItEFCHRFL
P07237 Y457 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB VHsFPtLKFFPAsADRtVIDyNGERtLDGFKKFLESGGQDG
P07237 Y94 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB GSEIRLAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPK
P07237 Y99 Sugiyama P4HB ERBA2L PDI PDIA1 PO4DB LAKVDAtEEsDLAQQyGVRGyPtIKFFRNGDTASPKEytAG
P07355 S164 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D NRVyKEMYKtDLEKDIIsDtsGDFRKLMVALAKGRRAEDGs
P07355 S184 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D sGDFRKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVK
P07355 Y188 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D RKLMVALAKGRRAEDGsVIDyELIDQDARDLyDAGVKRKGT
P07355 Y333 Sugiyama ANXA2 ANX2 ANX2L4 CAL1H LPC2D KsLyyyIQQDTKGDyQKALLyLCGGDD______________
P07437 Y50 Sugiyama TUBB TUBB5 OK/SW-cl.56 IDPTGtyHGDsDLQLDRIsVyyNEAtGGKyVPRAILVDLEP
P07602 S29 Sugiyama PSAP GLBA SAP1 SLLGAALAGPVLGLKECtRGsAVWCQNVKTASDCGAVKHCL
P07737 S58 Sugiyama PFN1 KtFVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsL
P07737 Y60 Sugiyama PFN1 FVNITPAEVGVLVGKDRssFyVNGLtLGGQKCsVIRDsLLQ
P07814 S335 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PIEKNLQMWEEMKKGsQFGQsCCLRAKIDMSSNNGCMRDPt
P07814 Y1504 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 KPLCELQPGAKCVCGKNPAKyytLFGRsy____________
P07814 Y1505 Sugiyama EPRS1 EPRS GLNS PARS QARS QPRS PIG32 PLCELQPGAKCVCGKNPAKyytLFGRsy_____________
P07858 Y215 Sugiyama CTSB CPSB RPPCTGEGDTPKCSKICEPGysPtyKQDKHYGYNSYSVSNS
P07864 S161 Sugiyama LDHC LDH3 LDHX DILTYIVWKISGLPVTRVIGsGCNLDsARFRYLIGEKLGVH
P07900 S391 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA MDNCEELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P07900 S505 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KENQKHIyyItGETKDQVANsAFVERLRKHGLEVIyMIEPI
P07900 S53 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IINtFySNKEIFLRELIsNssDALDKIRyEsLtDPsKLDsG
P07900 S63 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA IFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLIPN
P07900 Y284 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEEEEKKDGDKKKKKKIKEKyIDQEELNKtKPIWtRNPDDI
P07900 Y309 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA ELNKtKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHF
P07900 Y313 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA tKPIWtRNPDDItNEEyGEFyKsLtNDWEDHLAVKHFSVEG
P07900 Y466 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KLGIHEDsQNRKKLsELLRyytsAsGDEMVsLKDYCTRMKE
P07900 Y492 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA DEMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLR
P07900 Y493 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA EMVsLKDYCTRMKENQKHIyyItGETKDQVANsAFVERLRK
P07900 Y61 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA KEIFLRELIsNssDALDKIRyEsLtDPsKLDsGKELHINLI
P07900 Y627 Sugiyama HSP90AA1 HSP90A HSPC1 HSPCA TANMERIMKAQALRDNstMGyMAAKKHLEINPDHsIIEtLR
P08238 S383 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB MDSCDELIPEYLNFIRGVVDsEDLPLNIsREMLQQsKILKV
P08238 S460 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB GIHEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQ
P08238 S462 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB HEDstNRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKs
P08238 S468 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItG
P08238 S470 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB RLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyItGEs
P08238 S48 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IINTFYSNKEIFLRELIsNAsDALDKIRyEsLtDPsKLDsG
P08238 S497 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEtQKsIyyItGEsKEQVANsAFVERVRKRGFEVVyMtEPI
P08238 S58 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB IFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDIIPN
P08238 T467 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB NRRRLsELLRyHtsQsGDEMtsLsEyVsRMKEtQKsIyyIt
P08238 Y276 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEEDDsGKDKKKKTKKIKEKyIDQEELNKtKPIWtRNPDDI
P08238 Y301 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB ELNKtKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHF
P08238 Y305 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB tKPIWtRNPDDItQEEyGEFyKsLtNDWEDHLAVKHFSVEG
P08238 Y484 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB DEMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVR
P08238 Y485 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB EMtsLsEyVsRMKEtQKsIyyItGEsKEQVANsAFVERVRK
P08238 Y56 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB KEIFLRELIsNAsDALDKIRyEsLtDPsKLDsGKELKIDII
P08238 Y619 Sugiyama HSP90AB1 HSP90B HSPC2 HSPC3 HSPCB TANMERIMKAQALRDNstMGyMMAKKHLEINPDHPIVEtLR
P08758 Y94 Sugiyama ANXA5 ANX5 ENX2 PP4 TGKFEKLIVALMKPSRLyDAyELKHALKGAGTNEKVLtEII
P09382 S63 Sugiyama LGALS1 CLHFNPRFNAHGDANtIVCNsKDGGAWGTEQREAVFPFQPG
P09651 Y341 Sugiyama HNRNPA1 HNRPA1 QSSNFGPMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGss
P09651 Y347 Sugiyama HNRNPA1 HNRPA1 PMKGGNFGGRssGPyGGGGQyFAKPRNQGGyGGssssssyG
P0CG38 S1065 Sugiyama POTEI ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG38 S1068 Sugiyama POTEI SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG38 Y1062 Sugiyama POTEI GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0CG39 S1028 Sugiyama POTEJ ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
P0CG39 S1031 Sugiyama POTEJ SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
P0CG39 Y1025 Sugiyama POTEJ GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
P0DPH7 T223 Sugiyama TUBA3C TUBA2 MVDNEAIYDICRRNLDIERPtytNLNRLIGQIVSSITASLR
P10412 Y71 Sugiyama H1-4 H1F4 HIST1H1E SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P10809 S488 Sugiyama HSPD1 HSP60 IKRTLKIPAMtIAKNAGVEGsLIVEKIMQSSsEVGYDAMAG
P10809 Y223 Sugiyama HSPD1 HSP60 DGKtLNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAy
P10809 Y227 Sugiyama HSPD1 HSP60 LNDELEIIEGMKFDRGyIsPyFINtsKGQKCEFQDAyVLLs
P10809 Y243 Sugiyama HSPD1 HSP60 yIsPyFINtsKGQKCEFQDAyVLLsEKKIssIQsIVPALEI
P11142 S329 Sugiyama HSPA8 HSC70 HSP73 HSPA10 LFRGtLDPVEKALRDAKLDKsQIHDIVLVGGstRIPKIQKL
P11142 S340 Sugiyama HSPA8 HSC70 HSP73 HSPA10 ALRDAKLDKsQIHDIVLVGGstRIPKIQKLLQDFFNGKELN
P11142 T163 Sugiyama HSPA8 HSC70 HSP73 HSPA10 VVtVPAyFNDsQRQAtKDAGtIAGLNVLRIINEPtAAAIAy
P11142 Y134 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FYPEEVSSMVLTKMKEIAEAyLGKtVTNAVVtVPAyFNDsQ
P11142 Y41 Sugiyama HSPA8 HSC70 HSP73 HSPA10 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P11142 Y545 Sugiyama HSPA8 HSC70 HSP73 HSPA10 YKAEDEKQRDKVssKNsLEsyAFNMKATVEDEKLQGKINDE
P11586 T128 Sugiyama MTHFD1 MTHFC MTHFD SINTEEVINAIAPEKDVDGLtsINAGKLARGDLNDCFIPCt
P11940 Y194 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 KSRKEREAELGARAKEFtNVyIKNFGEDMDDERLKDLFGKF
P11940 Y291 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 ERQTELKRKFEQMKQDRITRyQGVNLyVKNLDDGIDDERLR
P11940 Y382 Sugiyama PABPC1 PAB1 PABP PABP1 PABPC2 PLyVALAQRKEERQAHLtNQyMQRMASVRAVPNPVINPYQP
P12814 Y193 Sugiyama ACTN1 WKDGLGFCALIHRHRPELIDyGKLRKDDPLTNLNTAFDVAE
P12814 Y378 Sugiyama ACTN1 GRMVSDINNAWGCLEQVEKGyEEWLLNEIRRLERLDHLAEK
P12814 Y859 Sugiyama ACTN1 DKNyITMDELRRELPPDQAEyCIARMAPYTGPDSVPGALDY
P12956 Y534 Sugiyama XRCC6 G22P1 MNKRLGsLVDEFKELVyPPDyNPEGKVtKRKHDNEGSGSKR
P13010 Y316 Sugiyama XRCC5 G22P2 CLNDDDETEVLKEDIIQGFRyGsDIVPFSKVDEEQMKYKSE
P13639 S23 Sugiyama EEF2 EF2 NFtVDQIRAIMDKKANIRNMsVIAHVDHGKStLtDsLVCKA
P13639 S38 Sugiyama EEF2 EF2 NIRNMsVIAHVDHGKStLtDsLVCKAGIIAsARAGEtRFtD
P13639 S593 Sugiyama EEF2 EF2 SDPVVsyREtVsEEsNVLCLsKsPNKHNRLyMKARPFPDGL
P13639 S732 Sugiyama EEF2 EF2 DAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQCP
P13639 Y634 Sugiyama EEF2 EF2 AEDIDKGEVsARQELKQRARyLAEKyEWDVAEARKIWCFGP
P13639 Y639 Sugiyama EEF2 EF2 KGEVsARQELKQRARyLAEKyEWDVAEARKIWCFGPDGTGP
P13639 Y671 Sugiyama EEF2 EF2 CFGPDGTGPNILTDITKGVQyLNEIKDSVVAGFQWATKEGA
P13639 Y730 Sugiyama EEF2 EF2 HADAIHRGGGQIIPtARRCLyAsVLtAQPRLMEPIyLVEIQ
P13667 S379 Sugiyama PDIA4 ERP70 ERP72 QPEKFQSKYEPRSHMMDVQGstQDsAIKDFVLKyALPLVGH
P13667 Y137 Sugiyama PDIA4 ERP70 ERP72 VAKIDAtsAsVLAsRFDVsGyPtIKILKKGQAVDyEGsRtQ
P13667 Y252 Sugiyama PDIA4 ERP70 ERP72 LAKVDAtAETDLAKRFDVsGyPTLKIFRKGRPYDYNGPREK
P13674 Y141 Sugiyama P4HA1 P4HA FPNDEDQVGAAKALLRLQDtyNLDTDtIsKGNLPGVKHKSF
P13674 Y282 Sugiyama P4HA1 P4HA ASDDQSDQKTTPKKKGVAVDyLPERQKyEMLCRGEGIKMTP
P13796 Y462 Sugiyama LCP1 PLS2 VNKPPYPKLGGNMKKLENCNyAVELGKNQAKFsLVGIGGQD
P13797 Y465 Sugiyama PLS3 VNKPPYPKLGANMKKLENCNyAVELGKHPAKFSLVGIGGQD
P14314 Y465 Sugiyama PRKCSH G19P1 sLGtWGsWIGPDHDKFSAMKyEQGtGCWQGPNRstTVRLLC
P14618 S202 Sugiyama PKM OIP3 PK2 PK3 PKM2 SLQVKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVs
P14618 S205 Sugiyama PKM OIP3 PK2 PK3 PKM2 VKQKGADFLVtEVENGGsLGsKKGVNLPGAAVDLPAVsEKD
P14618 S55 Sugiyama PKM OIP3 PK2 PK3 PKM2 IDsPPItARNtGIICtIGPAsRsVEtLKEMIKsGMNVARLN
P14618 Y370 Sugiyama PKM OIP3 PK2 PK3 PKM2 NAVLDGADCIMLSGEtAKGDyPLEAVRMQHLIAREAEAAIy
P14625 S109 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IINSLYKNKEIFLRELIsNAsDALDKIRLISLTDENALSGN
P14625 S172 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 VGMtREELVKNLGTIAKsGtsEFLNKMTEAQEDGQSTSELI
P14625 S64 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 tDDEVVQREEEAIQLDGLNAsQIRELREKSEKFAFQAEVNR
P14625 Y429 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 IKLYVRRVFITDDFHDMMPKyLNFVKGVVDsDDLPLNVsRE
P14625 Y527 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 AKLLRFQssHHPtDItsLDQyVERMKEKQDKIyFMAGsSRK
P14625 Y727 Sugiyama HSP90B1 GRP94 HSPC4 TRA1 DKTVLDLAVVLFETATLRsGyLLPDTKAYGDRIERMLRLsL
P14649 S87 Sugiyama MYL6B MLC1SA EEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVLK
P14649 Y86 Sugiyama MYL6B MLC1SA LEEFKEAFELFDRVGDGKILysQCGDVMRALGQNPtNAEVL
P14735 Y224 Sugiyama IDE LEKATGNPKHPFSKFGTGNKyTLETRPNQEGIDVRQELLKF
P15259 Y92 Sugiyama PGAM2 PGAMM DGTDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEEQV
P15531 S120 Sugiyama NME1 NDPKA NM23 KPGtIRGDFCIQVGRNIIHGsDsVEsAEKEIGLWFHPEELV
P16402 Y72 Sugiyama H1-3 H1F3 HIST1H1D SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P16403 Y71 Sugiyama H1-2 H1F2 HIST1H1C SKERsGVsLAALKKALAAAGyDVEKNNSRIKLGLKsLVsKG
P17066 Y43 Sugiyama HSPA6 HSP70B' FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P17812 Y468 Sugiyama CTPS1 CTPS MRLGKRRtLFQTKNsVMRKLyGDADyLEERHRHRFEVNPVW
P17987 S551 Sugiyama TCP1 CCT1 CCTA IKLHPESKDDKHGsyEDAVHsGALND_______________
P18206 S820 Sugiyama VCL DAKAVAGNIsDPGLQKsFLDsGyRILGAVAKVREAFQPQEP
P18621 S5 Sugiyama RPL17 ________________MVRysLDPENPtKsCKSRGSNLRVH
P18621 Y4 Sugiyama RPL17 _________________MVRysLDPENPtKsCKSRGSNLRV
P18669 Y142 Sugiyama PGAM1 PGAMA CDABP0006 PPPPMEPDHPFysNIsKDRRyADLtEDQLPsCEsLKDtIAR
P18669 Y92 Sugiyama PGAM1 PGAMA CDABP0006 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
P19105 Y155 Sugiyama MYL12A MLCB MRLC3 RLC DEEVDELyREAPIDKKGNFNyIEFtRILKHGAKDKDD____
P19338 S328 Sugiyama NCL NLFVGNLNFNKSAPELKtGIsDVFAKNDLAVVDVRIGMTRK
P19338 S458 Sugiyama NCL TEADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKN
P19338 S460 Sugiyama NCL ADAEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNST
P19338 Y462 Sugiyama NCL AEKTFEEKQGtEIDGRsIsLyytGEKGQNQDYRGGKNSTWs
P20042 Y176 Sugiyama EIF2S2 EIF2B GIsFsNQtGPAWAGSERDytyEELLNRVFNIMREKNPDMVA
P20618 S151 Sugiyama PSMB1 PSC5 PYYVYNIIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASA
P20618 S157 Sugiyama PSMB1 PSC5 IIGGLDEEGKGAVysFDPVGsyQRDsFKAGGSASAMLQPLL
P21333 Y2379 Sugiyama FLNA FLN FLN1 GAKGAIDAKVHsPsGALEECyVtEIDQDKYAVRFIPRENGV
P22061 S132 Sugiyama PCMT1 IKELVDDsVNNVRKDDPTLLssGRVQLVVGDGRMGYAEEAP
P22314 Y451 Sugiyama UBA1 A1S9T UBE1 CLPEDKEVLTEDKCLQRQNRyDGQVAVFGsDLQEKLGKQKY
P22314 Y845 Sugiyama UBA1 A1S9T UBE1 RLEELKATLPsPDKLPGFKMyPIDFEKDDDSNFHMDFIVAA
P22392 Y151 Sugiyama NME2 NM23B SLWFKPEELVDyKSCAHDWVyE___________________
P22492 Y75 Sugiyama H1-6 H1FT H1T HIST1H1T SQERVGMSLVALKKALAAAGyDVEKNNSRIKLSLKSLVNKG
P22626 S212 Sugiyama HNRNPA2B1 HNRPA2B1 EMQEVQssRsGRGGNFGFGDsRGGGGNFGPGPGsNFRGGsD
P22626 S225 Sugiyama HNRNPA2B1 HNRPA2B1 GNFGFGDsRGGGGNFGPGPGsNFRGGsDGyGsGRGFGDGyN
P22626 Y347 Sugiyama HNRNPA2B1 HNRPA2B1 MGGPyGGGNyGPGGsGGsGGyGGRsRy______________
P23284 Y119 Sugiyama PPIB CYPB DFMIQGGDFtRGDGtGGKsIyGERFPDENFKLKHyGPGWVs
P23284 Y133 Sugiyama PPIB CYPB tGGKsIyGERFPDENFKLKHyGPGWVsMANAGKDTNGsQFF
P23381 S357 Sugiyama WARS1 IFI53 WARS WRS STFFPALQGAQTKMsAsDPNssIFLtDtAKQIKTKVNKHAF
P23434 Y139 Sugiyama GCSH EVTEINEALAENPGLVNKSCyEDGWLIKMtLsNPsELDELM
P23526 Y165 Sugiyama AHCY SAHH QLLPGIRGIsEEtTTGVHNLyKMMANGILKVPAINVNDsVt
P23526 Y193 Sugiyama AHCY SAHH LKVPAINVNDsVtKsKFDNLyGCRESLIDGIKRATDVMIAG
P23528 S3 GPS6|SIGNOR|ELM|iPTMNet|EPSD|PSP CFL1 CFL __________________MAsGVAVsDGVIKVFNDMKVRKs
P23528 Y140 Sugiyama CFL1 CFL SKDAIKKKLtGIKHELQANCyEEVKDRCTLAEKLGGsAVIs
P24752 Y219 Sugiyama ACAT1 ACAT MAT NTAKKLNIARNEQDAyAINsytRSKAAWEAGKFGNEVIPVt
P25398 Y127 Sugiyama RPS12 sCVVVKDYGKESQAKDVIEEyFKCKK_______________
P25786 Y6 Sugiyama PSMA1 HC2 NU PROS30 PSC2 _______________MFRNQyDNDVtVWsPQGRIHQIEYAM
P25788 Y105 Sugiyama PSMA3 HC8 PSC8 ARSLADIAREEAsNFRSNFGyNIPLKHLADRVAMYVHAYTL
P26358 Y991 Sugiyama DNMT1 AIM CXXC9 DNMT EHyRKYSDYIKGSNLDAPEPyRIGRIKEIFCPKKSNGRPNE
P26639 Y575 Sugiyama TARS1 TARS YHQCATIQLDFQLPIRFNLtyVsHDGDDKKRPVIVHRAILG
P26885 Y112 Sugiyama FKBP2 FKBP13 GLLGMCEGEKRKLVIPsELGyGERGAPPKIPGGATLVFEVE
P27348 S145 Sugiyama YWHAQ YFRyLAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHP
P27348 Y149 Sugiyama YWHAQ LAEVACGDDRKQtIDNsQGAyQEAFDIsKKEMQPTHPIRLG
P27348 Y48 Sugiyama YWHAQ AVtEQGAELsNEERNLLsVAyKNVVGGRRSAWRVIsSIEQK
P27797 S52 Sugiyama CALR CRTC GWtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDA
P27797 S53 Sugiyama CALR CRTC WtsRWIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDAR
P27797 T34 Sugiyama CALR CRTC LAVAEPAVYFKEQFLDGDGWtsRWIEsKHKSDFGKFVLssG
P27797 Y109 Sugiyama CALR CRTC QTLVVQFTVKHEQNIDCGGGyVKLFPNSLDQTDMHGDSEYN
P27797 Y57 Sugiyama CALR CRTC WIEsKHKSDFGKFVLssGKFyGDEEKDKGLQTSQDARFyAL
P28074 Y171 Sugiyama PSMB5 LMPX MB1 X GMGLSMGTMICGWDKRGPGLyyVDsEGNRISGATFSVGSGS
P28074 Y172 Sugiyama PSMB5 LMPX MB1 X MGLSMGTMICGWDKRGPGLyyVDsEGNRISGATFSVGSGSV
P29144 Y118 Sugiyama TPP2 KIPASWTNPSGKYHIGIKNGyDFYPKALKERIQKERKEKIW
P29401 S190 Sugiyama TKT ASIYKLDNLVAILDINRLGQsDPAPLQHQMDIyQKRCEAFG
P29401 S308 Sugiyama TKT PPQEDAPsVDIANIRMPsLPsyKVGDKIATRKAYGQALAKL
P29692 S162 Sugiyama EEF1D EF1D AKKPAtPAEDDEDDDIDLFGsDNEEEDKEAAQLREERLRQY
P29692 S44 Sugiyama EEF1D EF1D RFyEQMNGPVAGAsRQENGAsVILRDIARARENIQKsLAGs
P29692 S64 Sugiyama EEF1D EF1D sVILRDIARARENIQKsLAGssGPGAssGtsGDHGELVVRI
P30041 Y89 Sugiyama PRDX6 AOP2 KIAA0106 IALSIDSVEDHLAWSKDINAyNCEEPtEKLPFPIIDDRNRE
P30043 S202 Sugiyama BLVRB FLR SCAN GHFMLRCLttDEyDGHstyPsHQyQ________________
P30086 T167 Sugiyama PEBP1 PBP PEBP GKFKVAsFRKKyELRAPVAGtCyQAEWDDyVPKLyEQLsGK
P30101 S98 Sugiyama PDIA3 ERP57 ERP60 GRP58 VPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGP
P30101 Y100 Sugiyama PDIA3 ERP57 ERP60 GRP58 LAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAyDGPRt
P30101 Y115 Sugiyama PDIA3 ERP57 ERP60 GRP58 yGVsGyPtLKIFRDGEEAGAyDGPRtADGIVsHLKKQAGPA
P30101 Y67 Sugiyama PDIA3 ERP57 ERP60 GRP58 LMLVEFFAPWCGHCKRLAPEyEAAAtRLKGIVPLAKVDCTA
P30101 Y95 Sugiyama PDIA3 ERP57 ERP60 GRP58 KGIVPLAKVDCTANTNTCNKyGVsGyPtLKIFRDGEEAGAy
P30533 Y246 Sugiyama LRPAP1 A2MRAP EKLRsINQGLDRLRRVsHQGystEAEFEEPRVIDLWDLAQS
P31153 Y235 Sugiyama MAT2A AMS2 MATA2 LDEMRDALKEKVIKAVVPAKyLDEDtIyHLQPsGRFVIGGP
P31327 Y582 Sugiyama CPS1 APsFAVEsIEDALKAADTIGyPVMIRSAyALGGLGsGICPN
P31943 Y266 Sugiyama HNRNPH1 HNRPH HNRPH1 yNGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGstFQst
P31946 Y50 Sugiyama YWHAB AVtEQGHELsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P31947 Y151 Sugiyama SFN HME1 LAEVATGDDKKRIIDSARsAyQEAMDISKKEMPPTNPIRLG
P31947 Y19 Sugiyama SFN HME1 __MERASLIQKAKLAEQAERyEDMAAFMKGAVEKGEELsCE
P31947 Y48 Sugiyama SFN HME1 GAVEKGEELsCEERNLLsVAyKNVVGGQRAAWRVLSsIEQK
P31948 Y354 Sugiyama STIP1 DVLKKCQQAEKILKEQERLAyINPDLALEEKNKGNECFQKG
P31948 Y376 Sugiyama STIP1 NPDLALEEKNKGNECFQKGDyPQAMKHYTEAIKRNPKDAKL
P31948 Y41 Sugiyama STIP1 DDALQCysEAIKLDPHNHVLysNRsAAyAKKGDYQKAyEDG
P32119 Y115 Sugiyama PRDX2 NKEFB TDPX1 GLGPLNIPLLADVTRRLsEDyGVLKTDEGIAYRGLFIIDGK
P32969 Y180 Sugiyama RPL9 OK/SW-cl.103; RPL9P7; RPL9P8; RPL9P9 LIQQATTVKNKDIRKFLDGIyVsEKGtVQQADE________
P33316 S164 Sugiyama DUT YTIPPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDV
P33316 Y167 Sugiyama DUT PPMEKAVVKTDIQIALPsGCyGRVAPRSGLAAKHFIDVGAG
P33993 Y393 Sugiyama MCM7 CDC47 MCM2 GNINICLMGDPGVAKSQLLsyIDRLAPRSQYTTGRGssGVG
P34931 Y43 Sugiyama HSPA1L FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P35609 Y385 Sugiyama ACTN2 GKMVSDIAGAWQRLEQAEKGyEEWLLNEIRRLERLEHLAEK
P37108 S25 Sugiyama SRP14 EsEQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGt
P37108 Y27 Sugiyama SRP14 EQFLtELTRLFQKCRTSGsVyItLKKYDGRTKPIPKKGtVE
P37802 Y192 Sugiyama TAGLN2 KIAA0120 CDABP0035 NVIGLQMGtNRGAsQAGMtGyGMPRQIL_____________
P38646 Y196 Sugiyama HSPA9 GRP75 HSPA9B mt-HSP70 EtAENyLGHtAKNAVItVPAyFNDsQRQAtKDAGQIsGLNV
P39019 Y48 Sugiyama RPS19 LKVPEWVDtVKLAKHKELAPyDENWFytRAAstARHLYLRG
P39019 Y54 Sugiyama RPS19 VDtVKLAKHKELAPyDENWFytRAAstARHLYLRGGAGVGs
P39023 S13 Sugiyama RPL3 OK/SW-cl.32 ________MSHRKFSAPRHGsLGFLPRKRSSRHRGKVKSFP
P39687 S104 Sugiyama ANP32A C15orf1 LANP MAPM PHAP1 AEKCPNLTHLNLsGNKIKDLstIEPLKKLENLKsLDLFNCE
P40227 S246 Sugiyama CCT6A CCT6 CCTZ EDAyILTCNVSLEYEKTEVNsGFFyKSAEEREKLVKAERKF
P40925 S153 Sugiyama MDH1 MDHA ANtNCLtAsKSAPSIPKENFsCLtRLDHNRAKAQIALKLGV
P40926 Y80 Sugiyama MDH2 HtPGVAADLsHIEtKAAVKGyLGPEQLPDCLKGCDVVVIPA
P42677 S78 Sugiyama RPS27 MPS1 GCSTVLCQPTGGKARLtEGCsFRRKQH______________
P45974 Y851 Sugiyama USP5 ISOT IYNDQKVCASEKPPKDLGyIyFyQRVAS_____________
P46060 S24 Sugiyama RANGAP1 KIAA1835 SD EDIAKLAETLAKTQVAGGQLsFKGKSLKLNTAEDAKDVIKE
P46776 S106 Sugiyama RPL27A tRVNAAKNKtGAAPIIDVVRsGyyKVLGKGKLPKQPVIVKA
P46776 Y108 Sugiyama RPL27A VNAAKNKtGAAPIIDVVRsGyyKVLGKGKLPKQPVIVKAKF
P46777 S172 Sugiyama RPL5 MSTP030 RTTTGNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNA
P46777 S176 Sugiyama RPL5 MSTP030 GNKVFGALKGAVDGGLsIPHstKRFPGyDsEsKEFNAEVHR
P46777 S224 Sugiyama RPL5 MSTP030 VADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEMyKKAH
P46777 Y210 Sugiyama RPL5 MSTP030 FNAEVHRKHIMGQNVADyMRyLMEEDEDAyKKQFsQyIKNs
P46777 Y219 Sugiyama RPL5 MSTP030 IMGQNVADyMRyLMEEDEDAyKKQFsQyIKNsVtPDMMEEM
P46783 S146 Sugiyama RPS10 TYRRSAVPPGADKKAEAGAGsAtEFQFRGGFGRGRGQPPQ_
P46940 Y1478 Sugiyama IQGAP1 KIAA0051 KIQTGLKKLTELGtVDPKNKyQELINDIARDIRNQRRYRQR
P47756 S192 Sugiyama CAPZB TVMLWLQTNKSGsGtMNLGGsLtRQMEKDEtVsDCsPHIAN
P47756 Y64 Sugiyama CAPZB DQPLKIARDKVVGKDyLLCDyNRDGDSyRsPWSNKyDPPLE
P48556 Y225 Sugiyama PSMD8 VAEFHTELERLPAKDIQTNVyIKHPVSLEQYLMEGSYNKVF
P48643 Y274 Sugiyama CCT5 CCTE KIAA0098 PFEPPKPKTKHKLDVtsVEDyKALQKYEKEKFEEMIQQIKE
P48741 Y43 Sugiyama HSPA7 HSP70B FQQGRVEILANDQGNRTtPsyVAFtDtERLVGDAAKsQAAL
P49207 Y32 Sugiyama RPL34 sYNtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGR
P49207 Y34 Sugiyama RPL34 NtASNKTRLSRTPGNRIVyLytKKVGKAPKSACGVCPGRLR
P49327 S2032 Sugiyama FASN FAS ELDYFVVFSSVSCGRGNAGQsNyGFANsAMERICEKRRHEG
P49327 Y2034 Sugiyama FASN FAS DYFVVFSSVSCGRGNAGQsNyGFANsAMERICEKRRHEGLP
P49327 Y2462 Sugiyama FASN FAS NVMLLRAKtGGAyGEDLGADyNLsQVCDGKVsVHVIEGDHR
P49327 Y45 Sugiyama FASN FAS NLIGGVDMVTDDDRRWKAGLyGLPRRsGKLKDLSRFDAsFF
P49588 S188 Sugiyama AARS1 AARS PGNMKDNFWEMGDtGPCGPCsEIHyDRIGGRDAAHLVNQDD
P49588 Y192 Sugiyama AARS1 AARS KDNFWEMGDtGPCGPCsEIHyDRIGGRDAAHLVNQDDPNVL
P50395 S396 Sugiyama GDI2 RABGDIB IEQKFVsISDLLVPKDLGtEsQIFIsRTyDAttHFEttCDD
P50502 Y185 Sugiyama ST13 AAG2 FAM10A1 HIP SNC6 NAAIRDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEAAHDL
P50990 Y173 Sugiyama CCT8 C21orf112 CCTQ KIAA0002 NLRDIDEVssLLRTSIMSKQyGNEVFLAKLIAQACVSIFPD
P51858 Y23 Sugiyama HDGF HMG1L2 RSNRQKEYKCGDLVFAKMKGyPHWPARIDEMPEAAVKstAN
P52597 Y82 Sugiyama HNRNPF HNRPF GsEDDVKMALKKDRESMGHRyIEVFKSHRTEMDWVLKHsGP
P53621 Y579 Sugiyama COPA GIIRTLDLPIyVTRVKGNNVyCLDRECRPRVLtIDPTEFKF
P53634 Y438 Sugiyama CTSC CPPI SGMDYWIVKNsWGtGWGENGyFRIRRGtDECAIEsIAVAAt
P53667 S298 EPSD|Sugiyama LIMK1 LIMK YTPSGEAGSSARQKPVLRsCsIDRsPGAGsLGsPAsQRKDL
P53667 S302 Sugiyama LIMK1 LIMK GEAGSSARQKPVLRsCsIDRsPGAGsLGsPAsQRKDLGRSE
P53667 S307 Sugiyama LIMK1 LIMK SARQKPVLRsCsIDRsPGAGsLGsPAsQRKDLGRSEsLRVV
P53667 S310 EPSD|Sugiyama LIMK1 LIMK QKPVLRsCsIDRsPGAGsLGsPAsQRKDLGRSEsLRVVCRP
P53667 S313 Sugiyama LIMK1 LIMK VLRsCsIDRsPGAGsLGsPAsQRKDLGRSEsLRVVCRPHRI
P53667 Y514 Sugiyama LIMK1 LIMK GLRSLKKPDRKKRYtVVGNPyWMAPEMINGRSYDEKVDVFS
P53667 Y552 Sugiyama LIMK1 LIMK VFSFGIVLCEIIGRVNADPDyLPRTMDFGLNVRGFLDRYCP
P53667 Y632 Sugiyama LIMK1 LIMK AGHLPLGPQLEQLDRGFWETyRRGESGLPAHPEVPD_____
P54652 Y42 Sugiyama HSPA2 FQHGKVEIIANDQGNRttPsyVAFtDtERLIGDAAKNQVAM
P55209 S69 Sugiyama NAP1L1 NRP LAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQVKCA
P55209 Y66 Sugiyama NAP1L1 NRP PQILAALQERLDGLVEtPtGyIEsLPRVVKRRVNALKNLQV
P55795 Y266 Sugiyama HNRNPH2 FTP3 HNRPH2 YGGYNDGYGFGSDRFGRDLNyCFsGMsDHRyGDGGssFQst
P57053 Y41 Sugiyama H2BC12L H2BFS H2BS1 KAQKKDGRKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P57721 S59 Sugiyama PCBP3 PCBP3-OT1 PCBP3OT EGGLNVTLTIRLLMHGKEVGsIIGKKGETVKKMREESGARI
P57723 S31 Sugiyama PCBP4 EPELSITLTLRMLMHGKEVGsIIGKKGETVKRIREQSSARI
P58876 Y41 Sugiyama H2BC5 H2BFB HIRIP2 HIST1H2BD KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
P60174 S212 Sugiyama TPI1 TPI WLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDGFLV
P60174 Y209 Sugiyama TPI1 TPI LRGWLKsNVsDAVAQstRIIyGGsVtGAtCKELASQPDVDG
P60228 Y445 Sugiyama EIF3E EIF3S6 INT6 KLNQNSRSEAPNWAtQDsGFy____________________
P60660 S30 Sugiyama MYL6 AEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVLK
P60660 Y29 Sugiyama MYL6 TAEFKEAFQLFDRtGDGKILysQCGDVMRALGQNPtNAEVL
P60660 Y89 Sugiyama MYL6 HFLPMLQTVAKNKDQGtyEDyVEGLRVFDKEGNGtVMGAEI
P60709 S199 Sugiyama ACTB DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P60709 S365 Sugiyama ACTB ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P60709 S368 Sugiyama ACTB sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P60709 Y198 Sugiyama ACTB LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P60709 Y240 Sugiyama ACTB ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P60709 Y362 Sugiyama ACTB GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P60842 Y70 Sugiyama EIF4A1 DDX2A EIF4A yGFEKPsAIQQRAILPCIKGyDVIAQAQsGtGKTATFAISI
P60981 S3 EPSD|PSP DSTN ACTDP DSN __________________MAsGVQVADEVCRIFYDMKVRKC
P61081 S175 Sugiyama UBE2M UBC12 NNRRLFEQNVQRSMRGGyIGstyFERCLK____________
P61081 Y172 Sugiyama UBE2M UBC12 VLQNNRRLFEQNVQRSMRGGyIGstyFERCLK_________
P61247 S203 Sugiyama RPS3A FTE1 MFTL EVVNKLIPDsIGKDIEKACQsIyPLHDVFVRKVKMLKKPKF
P61247 S236 Sugiyama RPS3A FTE1 MFTL KMLKKPKFELGKLMELHGEGsssGKAtGDEtGAKVERADGy
P61247 Y205 Sugiyama RPS3A FTE1 MFTL VNKLIPDsIGKDIEKACQsIyPLHDVFVRKVKMLKKPKFEL
P61247 Y256 Sugiyama RPS3A FTE1 MFTL sssGKAtGDEtGAKVERADGyEPPVQEsV____________
P61313 Y59 Sugiyama RPL15 EC45 TCBAP0781 APRPTRPDKARRLGYKAKQGyVIyRIRVRRGGRKRPVPKGA
P61313 Y6 Sugiyama RPL15 EC45 TCBAP0781 _______________MGAYKyIQELWRKKQSDVMRFLLRVR
P61353 Y77 Sugiyama RPL27 MGKKKIAKRSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVN
P61353 Y85 Sugiyama RPL27 RSKIKSFVKVyNyNHLMPtRysVDIPLDKtVVNKDVFRDPA
P61978 S401 Sugiyama HNRNPK HNRPK GDLGGPIIttQVtIPKDLAGsIIGKGGQRIKQIRHEsGAsI
P61978 Y72 Sugiyama HNRNPK HNRPK KNAGAVIGKGGKNIKALRtDyNAsVsVPDssGPERILsISA
P61981 Y49 Sugiyama YWHAG NVtELNEPLsNEERNLLsVAyKNVVGARRSsWRVIsSIEQK
P62249 S9 Sugiyama RPS16 ____________MPsKGPLQsVQVFGRKKTATAVAHCKRGN
P62258 Y152 Sugiyama YWHAE LAEFAtGNDRKEAAENsLVAyKAAsDIAMtELPPTHPIRLG
P62258 Y49 Sugiyama YWHAE KVAGMDVELTVEERNLLsVAyKNVIGARRASWRIIssIEQK
P62263 S70 Sugiyama RPS14 PRO2640 KETICRVTGGMKVKADRDEssPyAAMLAAQDVAQRCKELGI
P62269 S96 Sugiyama RPS18 D6S218E QYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLKK
P62269 Y95 Sugiyama RPS18 D6S218E RQYKIPDWFLNRQKDVKDGKysQVLANGLDNKLREDLERLK
P62273 Y7 Sugiyama RPS29 ______________MGHQQLyWsHPRKFGQGSRSCRVCSNR
P62277 S12 Sugiyama RPS13 _________MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDD
P62277 S14 Sugiyama RPS13 _______MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVK
P62277 Y18 Sugiyama RPS13 ___MGRMHAPGKGLsQsALPyRRsVPtWLKLTsDDVKEQIy
P62280 Y55 Sugiyama RPS11 RYYKNIGLGFKtPKEAIEGtyIDKKCPFTGNVsIRGRILsG
P62633 Y120 Sugiyama CNBP RNF163 ZNF9 NCGKPGHLARDCDHADEQKCysCGEFGHIQKDCTKVKCYRC
P62736 Y242 Sugiyama ACTA2 ACTSA ACTVS GIG46 ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P62807 Y41 Sugiyama H2BC4 H2BFL HIST1H2BC; H2BC6 H2BFH HIST1H2BE; H2BC7 H2BFG HIST1H2BF; H2BC8 H2BFA HIST1H2BG; H2BC10 H2BFK HIST1H2BI KAQKKDGKKRKRsRKEsysVyVyKVLKQVHPDTGIssKAMG
P62826 Y146 Sugiyama RAN ARA24 OK/SW-cl.81 IKDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLAR
P62826 Y147 Sugiyama RAN ARA24 OK/SW-cl.81 KDRKVKAKsIVFHRKKNLQyyDIsAKSNyNFEKPFLWLARK
P62857 S41 Sugiyama RPS28 tGsQGQCtQVRVEFMDDtsRsIIRNVKGPVREGDVLtLLEs
P62917 Y133 Sugiyama RPL8 VCCLEEKPGDRGKLARAsGNyAtVIsHNPEtKKtRVKLPSG
P62937 Y79 Sugiyama PPIA CYPA GFMCQGGDFtRHNGTGGKsIyGEKFEDENFILKHtGPGILs
P62979 Y148 Sugiyama RPS27A UBA80 UBCEP1 AGVFMAsHFDRHyCGKCCLtyCFNKPEDK____________
P63104 Y19 Sugiyama YWHAZ __MDKNELVQKAKLAEQAERyDDMAACMKsVtEQGAELsNE
P63104 Y48 Sugiyama YWHAZ sVtEQGAELsNEERNLLsVAyKNVVGARRssWRVVssIEQK
P63172 Y34 Sugiyama DYNLT1 TCTEL1 TCTEX-1 TCTEX1 VDEVSNIVKEAIESAIGGNAyQHSKVNQWTTNVVEQTLSQL
P63220 T52 Sugiyama RPS21 IQMNVAEVDKVTGRFNGQFKtyAICGAIRRMGEsDDsILRL
P63261 S199 Sugiyama ACTG1 ACTG DLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCyV
P63261 S365 Sugiyama ACTG1 ACTG ILAsLstFQQMWISKQEyDEsGPsIVHRKCF__________
P63261 S368 Sugiyama ACTG1 ACTG sLstFQQMWISKQEyDEsGPsIVHRKCF_____________
P63261 Y198 Sugiyama ACTG1 ACTG LDLAGRDLTDyLMKILtERGysFtttAEREIVRDIKEKLCy
P63261 Y240 Sugiyama ACTG1 ACTG ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
P63261 Y362 Sugiyama ACTG1 ACTG GGsILAsLstFQQMWISKQEyDEsGPsIVHRKCF_______
P63267 Y241 Sugiyama ACTG2 ACTA3 ACTL3 ACTSG ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P67809 S136 Sugiyama YBX1 NSEP1 YB1 GEKGAEAANVtGPGGVPVQGsKYAADRNHYRRYPRRRGPPR
P67809 Y196 Sugiyama YBX1 NSEP1 YB1 sAPEGQAQQRRPyRRRRFPPyyMRRPYGRRPQysNPPVQGE
P67809 Y72 Sugiyama YBX1 NSEP1 YB1 KKVIATKVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
P67936 T237 Sugiyama TPM4 IDDLEEKLAQAKEENVGLHQtLDQtLNELNCI_________
P67936 T241 Sugiyama TPM4 EEKLAQAKEENVGLHQtLDQtLNELNCI_____________
P68032 Y242 Sugiyama ACTC1 ACTC ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68104 Y29 Sugiyama EEF1A1 EEF1A EF1A LENG7 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
P68133 Y242 Sugiyama ACTA1 ACTA ALDFENEMAtAAssssLEKsyELPDGQVItIGNERFRCPET
P68363 T223 Sugiyama TUBA1B MVDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLR
P68363 Y451 Sugiyama TUBA1B DyEEVGVDsVEGEGEEEGEEy____________________
P68366 T223 Sugiyama TUBA4A TUBA1 MVDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLR
P83731 S38 Sugiyama RPL24 GRRYARTDGKVFQFLNAKCEsAFLSKRNPRQINWtVLyRRK
P83731 Y11 Sugiyama RPL24 __________MKVELCsFsGyKIYPGHGRRYARTDGKVFQF
P98082 Y38 Sugiyama DAB2 DOC2 AAPKAPsKKEKKKGPEKTDEyLLARFKGDGVKYKAKLIGID
Q00610 Y883 Sugiyama CLTC CLH17 CLTCL2 KIAA0034 EARIHEGCEEPAtHNALAKIyIDsNNNPERFLRENPyyDsR
Q00839 Y257 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 QKGGDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVE
Q00839 Y260 Sugiyama HNRNPU C1orf199 HNRPU SAFA U21.1 GDKKRGVKRPREDHGRGyFEyIEENKysRAKsPQPPVEEED
Q01105 T169 Sugiyama SET NKVLSKEFHLNEsGDPssKstEIKWKSGKDLTKRssQTQNK
Q01105 Y146 Sugiyama SET tEFEDIKsGyRIDFyFDENPyFENKVLSKEFHLNEsGDPss
Q02539 Y74 Sugiyama H1-1 H1F1 HIST1H1A SKERGGVSLAALKKALAAAGyDVEKNNSRIKLGIKsLVsKG
Q02878 Y115 Sugiyama RPL6 TXREB1 PVGGDKNGGTRVVKLRKMPRyyPtEDVPRKLLSHGKKPFSQ
Q02878 Y216 Sugiyama RPL6 TXREB1 AtsTKIDISNVKIPKHLtDAyFKKKKLRKPRHQEGEIFDtE
Q04760 Y115 Sugiyama GLO1 RKATLELTHNWGtEDDEtQsyHNGNsDPRGFGHIGIAVPDV
Q04917 Y49 Sugiyama YWHAH YWHA1 AVtELNEPLsNEDRNLLsVAyKNVVGARRSsWRVIsSIEQK
Q05639 Y29 Sugiyama EEF1A2 EEF1AL STN NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q06830 S32 Sugiyama PRDX1 PAGA PAGB TDPX2 APNFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTFVC
Q06830 Y116 Sugiyama PRDX1 PAGA PAGB TDPX2 GLGPMNIPLVSDPKRtIAQDyGVLKADEGIsFRGLFIIDDK
Q06830 Y34 Sugiyama PRDX1 PAGA PAGB TDPX2 NFKAtAVMPDGQFKDIsLsDyKGKYVVFFFYPLDFTFVCPT
Q07866 Y474 Sugiyama KLC1 KLC KNS2 KACKVDsPtVTTtLKNLGALyRRQGKFEAAETLEEAAMRSR
Q08211 Y68 Sugiyama DHX9 DDX9 LKP NDH2 MGNSTNKKDAQSNAARDFVNyLVRINEIKsEEVPAFGVAsP
Q08752 Y323 Sugiyama PPID CYP40 CYPD DPSNTKALYRRAQGWQGLKEyDQALADLKKAQGIAPEDKAI
Q13263 S784 Sugiyama TRIM28 KAP1 RNF96 TIF1B DVGRMFKQFNKLTEDKADVQsIIGLQRFFETRMNEAFGDTK
Q13263 Y133 Sugiyama TRIM28 KAP1 RNF96 TIF1B TVVDCPVCKQQCFSKDIVENyFMRDsGsKAATDAQDANQCC
Q13283 Y125 Sugiyama G3BP1 G3BP LRRFMQtFVLAPEGsVANKFyVHNDIFRyQDEVFGGFVtEP
Q13303 Y270 Sugiyama KCNAB2 KCNA2B KCNK2 IVSGKYDSGIPPYSRAsLKGyQWLKDKILSEEGRRQQAKLK
Q13310 Y194 Sugiyama PABPC4 APP1 PABP4 KSRKEREAELGAKAKEFtNVyIKNFGEEVDDEsLKELFsQF
Q13547 S88 Sugiyama HDAC1 RPD3L1 HSDDyIKFLRSIRPDNMsEysKQMQRFNVGEDCPVFDGLFE
Q13573 Y260 Sugiyama SNW1 SKIIP SKIP KEQQEWKIPPCISNWKNAKGytIPLDKRLAADGRGLQTVHI
Q13765 Y120 Sugiyama NACA HSD48 KNILFVITKPDVYKSPAsDtyIVFGEAKIEDLsQQAQLAAA
Q14157 Y858 Sugiyama UBAP2L KIAA0144 NICE4 PFPtPttPLtGRDGsLAsNPysGDLtKFGRGDASSPAPATT
Q14240 Y71 Sugiyama EIF4A2 DDX2B EIF4F yGFEKPsAIQQRAIIPCIKGyDVIAQAQsGtGKTATFAISI
Q14568 S53 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 IINTFYSNKEIFLRELIsNssDALDKIWYESLTDPSKLDSG
Q14568 Y283 Sugiyama HSP90AA2P HSP90AA2 HSPC2 HSPCAL3 sDEEEEKKDGDKKKKKTKEKyIDQEELNKTKPIWTRNPDDI
Q14980 S1183 Sugiyama NUMA1 NMP22 NUMA ALEtLQGQLEEKAQELGHsQsALAsAQRELAAFRTKVQDHS
Q15181 S127 Sugiyama PPA1 IOPPP PP NDKHTGCCGDNDPIDVCEIGsKVCARGEIIGVKVLGILAMI
Q15293 Y115 Sugiyama RCN1 RCN GDGFVttEELKtWIKRVQKRyIFDNVAKVWKDYDRDKDDKI
Q15293 Y278 Sugiyama RCN1 RCN LNKDGKLDKDEIRHWILPQDyDHAQAEARHLVyESDKNKDE
Q15365 S27 Sugiyama PCBP1 ESGLNVTLTIRLLMHGKEVGsIIGKKGESVKRIREEsGARI
Q15366 S27 Sugiyama PCBP2 EGGLNVTLTIRLLMHGKEVGsIIGKKGESVKKMREESGARI
Q16543 Y248 Sugiyama CDC37 CDC37A VDPRACFRQFFTKIKtADRQyMEGFNDELEAFKERVRGRAK
Q16719 Y47 Sugiyama KYNU ERVALHLDEEDKLRHFRECFyIPKIQDLPPVDLSLVNKDEN
Q16719 Y86 Sugiyama KYNU ENAIYFLGNSLGLQPKMVKtyLEEELDKWAKIAAYGHEVGK
Q4VXU2 Y291 Sugiyama PABPC1L C20orf119 ERQNELKRRFEQMKQDRLRRyQGVNLyVKNLDDSIDDDKLR
Q562R1 Y241 Sugiyama ACTBL2 ALDFEQEMVRAAAssSPERsyELPDGQVItIGNERFRCPEA
Q58FF6 S34 Sugiyama HSP90AB4P IFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDIIPN
Q58FF6 Y32 Sugiyama HSP90AB4P KEIFLQELISNASDALDKIRyEsLtDPsKLDGGKELKIDII
Q58FF7 S370 Sugiyama HSP90AB3P HSP90BC KETQKSTYYITGESKEQVANsAFVERVRKQGFEVVYMTEPI
Q58FF7 S58 Sugiyama HSP90AB3P HSP90BC IFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF7 Y492 Sugiyama HSP90AB3P HSP90BC TANMEQIMKAQALRDNstMGyMMAKKHLEINPDHPIMETLR
Q58FF7 Y56 Sugiyama HSP90AB3P HSP90BC EEIFLQELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FF8 S58 Sugiyama HSP90AB2P HSP90BB IFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDIIPN
Q58FF8 Y198 Sugiyama HSP90AB2P HSP90BB DEEDDsGKDKKKKTKKIKEKyIDQEELNKTKPIWTRNTEDI
Q58FF8 Y260 Sugiyama HSP90AB2P HSP90BB VRYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVW
Q58FF8 Y261 Sugiyama HSP90AB2P HSP90BB RYFSVEEYVSRMKEIQKsIyyItGEsKEQVANSAFVEQVWK
Q58FF8 Y56 Sugiyama HSP90AB2P HSP90BB KEIFLWELISNASDALDKIRyEsLtDPsKLDsGKELKIDII
Q58FG0 Y177 Sugiyama HSP90AA5P HSP90AE GQLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQ
Q58FG0 Y178 Sugiyama HSP90AA5P HSP90AE QLEELKDSRRVMKANQKHIyyItGETKDQVANSAFVECLQK
Q5QNW6 Y41 Sugiyama H2BC18 HIST2H2BF KVQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q5VTE0 Y29 Sugiyama EEF1A1P5 EEF1AL3 NIVVIGHVDsGKstttGHLIyKCGGIDKRTIEKFEKEAAEM
Q6PEY2 T223 Sugiyama TUBA3E MVDNEAIYDICRRNLDIERPtytNLNRLIGQIVSSITASLR
Q6S8J3 S1065 Sugiyama POTEE A26C1A POTE2 ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q6S8J3 S1068 Sugiyama POTEE A26C1A POTE2 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q6S8J3 Y1062 Sugiyama POTEE A26C1A POTE2 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q6S8J3 Y940 Sugiyama POTEE A26C1A POTE2 ALDFEQEMAtAAssssLEKsyELPDGQVItIGNERFRCPEA
Q6ZMR3 S161 Sugiyama LDHAL6A LDHL2 DILTYVAWKLSGFPKNRVIGsGCNLDsARFRYFIGQRLGIH
Q71U36 T223 Sugiyama TUBA1A TUBA3 MVDNEAIYDICRRNLDIERPtytNLNRLIGQIVSSITASLR
Q71U36 Y451 Sugiyama TUBA1A TUBA3 DyEEVGVDsVEGEGEEEGEEy____________________
Q71UM5 S78 Sugiyama RPS27L GCSTVLCQPTGGKARLtEGCsFRRKQH______________
Q7KZF4 S474 Sugiyama SND1 TDRD11 LVSKGLATVIRYRQDDDQRssHyDELLAAEARAIKNGKGLH
Q7KZF4 S727 Sugiyama SND1 TDRD11 LEKLMENMRNDIAsHPPVEGsyAPRRGEFCIAKFVDGEWYR
Q7Z4V5 Y18 Sugiyama HDGFL2 HDGF2 HDGFRP2 HRP2 UNQ785/PRO1604 ___MPHAFKPGDLVFAKMKGyPHWPARIDDIADGAVKPPPN
Q86U86 S267 Sugiyama PBRM1 BAF180 PB1 AMAKDIDLLAKNAKTYNEPGsQVFKDANSIKKIFYMKKAEI
Q8N0Y7 Y92 Sugiyama PGAM4 PGAM3 DAIDQMWLPVVRTWRLNERHyGGLtGLNKAETAAKHGEAQV
Q8NBJ7 S264 Sugiyama SUMF2 PSEC0171 UNQ1968/PRO4500 AAEQDMRVLRGAsWIDtADGsANHRARVttRMGNtPDsAsD
Q8NFI4 Y185 Sugiyama ST13P5 FAM10A5 NAAIQDCDRAIEINPDsAQPyKWRGKAHRLLGHWEEAAHDL
Q8NHW5 S307 Sugiyama RPLP0P6 AAPAAAAAPAKVEAKEEsEEsDEDMGFGLFD__________
Q8WUM4 Y223 Sugiyama PDCD6IP AIP1 ALIX KIAA1375 ATRDKMKDAIIAKLANQAADyFGDAFKQCQYKDTLPKEVFP
Q92526 S246 Sugiyama CCT6B EDAFILICNVSLEYEKTEVNsGFFyKTAEEKEKLVKAERKF
Q92769 S89 Sugiyama HDAC2 HSDEYIKFLRSIRPDNMsEysKQMQRFNVGEDCPVFDGLFE
Q92878 Y1081 Sugiyama RAD50 EENIDNIKRNHNLALGRQKGyEEEIIHFKKELREPQFRDAE
Q93079 Y41 Sugiyama H2BC9 H2BFJ HIST1H2BH KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q96AE4 S52 Sugiyama FUBP1 KDALQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQ
Q96AE4 S55 Sugiyama FUBP1 LQRARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQPDA
Q96AE4 Y58 Sugiyama FUBP1 ARQIAAKIGGDAGtsLNsNDyGyGGQKRPLEDGDQPDAKKV
Q96C19 T84 Sugiyama EFHD2 SWS1 DLNQGIGEPQsPsRRVFNPytEFKEFSRKQIKDMEKMFKQy
Q96C19 Y83 Sugiyama EFHD2 SWS1 ADLNQGIGEPQsPsRRVFNPytEFKEFSRKQIKDMEKMFKQ
Q96MG8 Y350 Sugiyama PCMTD1 PQNLLREKIMKLPLPESLKAyLTYFRDK_____________
Q96QK1 Y507 Sugiyama VPS35 MEM3 TCCCTA00141 EQSLVGRFIHLLRsEDPDQQyLILNTARKHFGAGGNQRIRF
Q99426 Y133 Sugiyama TBCB CG22 CKAP1 AyDQRQDtVRSFLKRsKLGRyNEEERAQQEAEAAQRLAEEK
Q99459 Y788 Sugiyama CDC5L KIAA0432 PCDC5RP ECLKEDVQRQQEREKELQHRyADLLLEKETLKSKF______
Q99613 S865 Sugiyama EIF3C EIF3S8 HRTEPTAQQNLALQLAEKLGsLVENNERVFDHKQGtyGGyF
Q99613 Y148 Sugiyama EIF3C EIF3S8 KKMNKNNAKALSTLRQKIRKyNRDFEsHItSyKQNPEQsAD
Q99613 Y881 Sugiyama EIF3C EIF3S8 EKLGsLVENNERVFDHKQGtyGGyFRDQKDGYRKNEGYMRR
Q99877 Y41 Sugiyama H2BC15 H2BFD HIST1H2BN KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99879 Y41 Sugiyama H2BC14 H2BFE HIST1H2BM KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q99880 Y41 Sugiyama H2BC13 H2BFC HIST1H2BL KAQKKDGKKRKRSRKEsysVyVyKVLKQVHPDTGIssKAMG
Q9BQE3 T223 Sugiyama TUBA1C TUBA6 MVDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLR
Q9BQE3 Y449 Sugiyama TUBA1C TUBA6 EKDyEEVGADsADGEDEGEEy____________________
Q9BRA2 S41 Sugiyama TXNDC17 TXNL5 QHNGKTIFAyFTGSKDAGGKsWCPDCVQAEPVVREGLKHIS
Q9BT78 S297 Sugiyama COPS4 CSN4 QLQEFAAMLMPHQKATTADGssILDRAVIEHNLLSASKLYN
Q9BT78 S298 Sugiyama COPS4 CSN4 LQEFAAMLMPHQKATTADGssILDRAVIEHNLLSASKLYNN
Q9BYX7 S365 Sugiyama POTEKP ACTBL3 FKSG30 ILASLSTFQQMWISKQEyDEsGPsIVHRKCF__________
Q9BYX7 S368 Sugiyama POTEKP ACTBL3 FKSG30 SLSTFQQMWISKQEyDEsGPsIVHRKCF_____________
Q9BYX7 Y240 Sugiyama POTEKP ACTBL3 FKSG30 ALDSEQEMAMAASSSSVEKsyELPDGQVItIGNERFRCPEA
Q9BYX7 Y362 Sugiyama POTEKP ACTBL3 FKSG30 GGSILASLSTFQQMWISKQEyDEsGPsIVHRKCF_______
Q9HB71 T167 Sugiyama CACYBP S100A6BP SIP PNAS-107 TDTVLILCRKKVENTRWDyLtQVEKECKEKEKPsYDtEtDP
Q9HB71 Y165 Sugiyama CACYBP S100A6BP SIP PNAS-107 VKTDTVLILCRKKVENTRWDyLtQVEKECKEKEKPsYDtEt
Q9NQ39 S157 Sugiyama RPS10P5 RPS10L TYRRCSVPPGADKKAEAGAGsAtEFQFRGRCGRGRGQPPQ_
Q9NSK0 Y474 Sugiyama KLC4 KNSL8 KACKVssPTVNTTLRNLGALyRRQGKLEAAETLEECALRSR
Q9NW13 Y737 Sugiyama RBM28 SRKKAKGNKTETRFNQLVEQyKQKLLGPSKGAPLAKRSKWF
Q9NY65 T223 Sugiyama TUBA8 TUBAL2 MVDNEAIYDICRRNLDIERPtytNLNRLIsQIVSsITASLR
Q9NYU2 Y1516 Sugiyama UGGT1 GT UGCGL1 UGGT UGT1 UGTR PMTKEPKLEAAVRIVPEWQDyDQEIKQLQIRFQKEKETGAL
Q9UBQ5 Y21 Sugiyama EIF3K EIF3S12 ARG134 HSPC029 MSTP001 PTD001 MAMFEQMRANVGKLLKGIDRyNPENLAtLERYVETQAKENA
Q9UBR2 S78 Sugiyama CTSZ SPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHAST
Q9UBR2 Y76 Sugiyama CTSZ YLSPADLPKSWDWRNVDGVNyAsItRNQHIPQYCGSCWAHA
Q9UHX1 Y269 Sugiyama PUF60 FIR ROBPI SIAHBP1 FGKIKSCTLARDPTTGKHKGyGFIEyEKAQSSQDAVSSMNL
Q9UI15 Y192 Sugiyama TAGLN3 NP25 NVIGLQMGSNKGAsQAGMtGyGMPRQIM_____________
Q9UKS6 Y206 Sugiyama PACSIN3 RKLQERVERCAKEAEKTKAQyEQtLAELHRYTPRYMEDMEQ
Q9UKS6 Y53 Sugiyama PACSIN3 HRLCGDLVSCFQERARIEKAyAQQLADWARKWRGTVEKGPQ
Q9Y281 S3 GPS6|SIGNOR|ELM|iPTMNet|EPSD CFL2 __________________MAsGVtVNDEVIKVFNDMKVRKs
Q9Y2B0 S65 Sugiyama CNPY2 MSAP TMEM4 ZSIG9 UNQ1943/PRO4426 VDPKKTIQMGsFRINPDGsQsVVEVPyARsEAHLtELLEEI
Q9Y2G5 Y228 Sugiyama POFUT2 C21orf80 FUT13 KIAA0958 RNTSARSVMLDRAENLLHDHyGGKEYWDTRRSMVFARHLRE
Q9Y2T7 Y107 Sugiyama YBX2 CSDA3 MSY2 KPVLAIQVLGTVKWFNVRNGyGFINRNDtKEDVFVHQtAIK
Q9Y3B8 Y210 Sugiyama REXO2 SFN SMFN CGI-114 KAAsHRALDDIsEsIKELQFyRNNIFKKKIDEKKRKIIENG
Q9Y3E1 Y22 Sugiyama HDGFL3 HDGF2 HDGFRP3 CGI-142 ARPRPREYKAGDLVFAKMKGyPHWPARIDELPEGAVKPPAN
Q9Y3U8 Y53 Sugiyama RPL36 LTKHTKFVRDMIREVCGFAPyERRAMELLKVSKDKRALKFI
Q9Y5M8 S257 Sugiyama SRPRB PSEC0230 LPLKVEFLECSAKGGRGDVGsADIQDLEKWLAKIA______
Q9Y696 S226 Sugiyama CLIC4 RNFDIPKEMTGIWRYLtNAysRDEFtNtCPsDKEVEIAysD
Q9Y6E0 Y295 Sugiyama STK24 MST3 STK3 PTAKELLKHKFILRNAKKTsyLtELIDRYKRWKAEQSHDDS
Site Promiscuity
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
Signaling by ALK in cancer R-HSA-9700206 5.321465e-10 9.274 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 5.321465e-10 9.274 0 0
Signaling by Interleukins R-HSA-449147 7.117839e-08 7.148 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 2.140773e-07 6.669 0 0
Cytokine Signaling in Immune system R-HSA-1280215 1.009649e-06 5.996 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.394933e-06 5.621 0 0
Immune System R-HSA-168256 9.249425e-05 4.034 1 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 1.937816e-04 3.713 0 0
Interleukin-2 family signaling R-HSA-451927 1.458041e-04 3.836 0 0
Interleukin receptor SHC signaling R-HSA-912526 2.602250e-04 3.585 0 0
Interleukin-20 family signaling R-HSA-8854691 2.602250e-04 3.585 0 0
Signaling by SCF-KIT R-HSA-1433557 2.121821e-04 3.673 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 3.515637e-04 3.454 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.983994e-04 3.400 0 0
Downstream signal transduction R-HSA-186763 6.467029e-04 3.189 0 0
GPVI-mediated activation cascade R-HSA-114604 1.124406e-03 2.949 0 0
Signaling by ALK R-HSA-201556 1.437710e-03 2.842 0 0
MTF1 activates gene expression R-HSA-5660489 1.847254e-03 2.733 0 0
Pyrophosphate hydrolysis R-HSA-71737 2.497291e-03 2.603 0 0
Signaling by PDGFR in disease R-HSA-9671555 2.927709e-03 2.533 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 4.832076e-03 2.316 0 0
Signaling by Erythropoietin R-HSA-9006335 6.004727e-03 2.222 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 6.001761e-03 2.222 0 0
Signaling by PDGF R-HSA-186797 6.369788e-03 2.196 0 0
Drug resistance of ALK mutants R-HSA-9700649 1.031747e-02 1.986 0 0
Drug resistance of PDGFR mutants R-HSA-9674415 1.031747e-02 1.986 0 0
PDGFR mutants bind TKIs R-HSA-9674428 1.031747e-02 1.986 0 0
Regorafenib-resistant PDGFR mutants R-HSA-9674403 1.031747e-02 1.986 0 0
brigatinib-resistant ALK mutants R-HSA-9717319 1.031747e-02 1.986 0 0
ASP-3026-resistant ALK mutants R-HSA-9717264 1.031747e-02 1.986 0 0
crizotinib-resistant ALK mutants R-HSA-9717326 1.031747e-02 1.986 0 0
NVP-TAE684-resistant ALK mutants R-HSA-9717301 1.031747e-02 1.986 0 0
ceritinib-resistant ALK mutants R-HSA-9717323 1.031747e-02 1.986 0 0
alectinib-resistant ALK mutants R-HSA-9717316 1.031747e-02 1.986 0 0
lorlatinib-resistant ALK mutants R-HSA-9717329 1.031747e-02 1.986 0 0
Sunitinib-resistant PDGFR mutants R-HSA-9674401 1.031747e-02 1.986 0 0
Imatinib-resistant PDGFR mutants R-HSA-9674396 1.031747e-02 1.986 0 0
Sorafenib-resistant PDGFR mutants R-HSA-9674404 1.031747e-02 1.986 0 0
ALK mutants bind TKIs R-HSA-9700645 7.094421e-03 2.149 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 7.513833e-03 2.124 0 0
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) R-HSA-9027276 1.227618e-02 1.911 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.156575e-02 1.937 0 0
Regulation of IFNG signaling R-HSA-877312 1.227618e-02 1.911 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.266147e-02 1.898 0 0
Prolactin receptor signaling R-HSA-1170546 1.532914e-02 1.814 0 0
CD28 dependent Vav1 pathway R-HSA-389359 1.376558e-02 1.861 0 0
Signaling by VEGF R-HSA-194138 1.592207e-02 1.798 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 1.597063e-02 1.797 1 0
RAF/MAP kinase cascade R-HSA-5673001 1.594316e-02 1.797 0 0
MAPK family signaling cascades R-HSA-5683057 1.497708e-02 1.825 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.464033e-02 1.834 0 0
Erythropoietin activates RAS R-HSA-9027284 1.696517e-02 1.770 0 0
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants R-HSA-9673767 1.696517e-02 1.770 0 0
Signaling by PDGFRA extracellular domain mutants R-HSA-9673770 1.696517e-02 1.770 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 1.796618e-02 1.746 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 1.822092e-02 1.739 0 0
Signal Transduction R-HSA-162582 1.848197e-02 1.733 1 0
Apoptotic execution phase R-HSA-75153 1.913347e-02 1.718 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 2.006648e-02 1.698 0 0
Response to metal ions R-HSA-5660526 2.044813e-02 1.689 0 0
Co-stimulation by CD28 R-HSA-389356 2.102421e-02 1.677 0 0
Ephrin signaling R-HSA-3928664 2.420163e-02 1.616 0 0
mRNA Splicing - Major Pathway R-HSA-72163 2.444926e-02 1.612 0 0
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1234176 2.404579e-02 1.619 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 2.420163e-02 1.616 0 0
Interferon Signaling R-HSA-913531 2.585910e-02 1.587 0 0
Tie2 Signaling R-HSA-210993 2.420163e-02 1.616 0 0
FOXO-mediated transcription of cell death genes R-HSA-9614657 2.420163e-02 1.616 0 0
Cell-Cell communication R-HSA-1500931 2.475557e-02 1.606 0 0
Regulation of signaling by CBL R-HSA-912631 2.617593e-02 1.582 0 0
Nef mediated downregulation of CD28 cell surface expression R-HSA-164939 3.063602e-02 1.514 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 4.063925e-02 1.391 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 4.063925e-02 1.391 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages) R-HSA-5619049 4.063925e-02 1.391 0 0
Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum) R-HSA-5655799 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 4.063925e-02 1.391 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 4.063925e-02 1.391 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 4.063925e-02 1.391 0 0
Glycogen storage disease type IV (GBE1) R-HSA-3878781 4.063925e-02 1.391 0 0
mRNA Splicing R-HSA-72172 3.020042e-02 1.520 0 0
Nephrin family interactions R-HSA-373753 2.821323e-02 1.550 0 0
Regulation of IFNA/IFNB signaling R-HSA-912694 3.468833e-02 1.460 0 0
Interferon gamma signaling R-HSA-877300 3.813696e-02 1.419 0 0
Growth hormone receptor signaling R-HSA-982772 3.696294e-02 1.432 0 0
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants R-HSA-9670439 3.468833e-02 1.460 0 0
Neurophilin interactions with VEGF and VEGFR R-HSA-194306 4.063925e-02 1.391 0 0
Signaling by KIT in disease R-HSA-9669938 3.468833e-02 1.460 0 0
Signaling by ERBB2 R-HSA-1227986 3.444176e-02 1.463 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 2.909449e-02 1.536 0 0
Regulation of CDH1 Function R-HSA-9764561 3.075562e-02 1.512 0 0
TCR signaling R-HSA-202403 3.907630e-02 1.408 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 3.696294e-02 1.432 0 0
Axon guidance R-HSA-422475 3.471966e-02 1.459 1 0
Cellular response to chemical stress R-HSA-9711123 3.150147e-02 1.502 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 2.835627e-02 1.547 0 0
Death Receptor Signaling R-HSA-73887 3.440282e-02 1.463 0 0
Zygotic genome activation (ZGA) R-HSA-9819196 3.031204e-02 1.518 0 0
Interleukin-1 family signaling R-HSA-446652 3.297558e-02 1.482 0 0
Apoptosis R-HSA-109581 4.049219e-02 1.393 0 0
Cellular response to hypoxia R-HSA-1234174 4.106947e-02 1.386 0 0
Interferon alpha/beta signaling R-HSA-909733 4.626303e-02 1.335 0 0
Interaction between L1 and Ankyrins R-HSA-445095 4.660540e-02 1.332 0 0
CD28 dependent PI3K/Akt signaling R-HSA-389357 4.660540e-02 1.332 0 0
Maturation of hRSV A proteins R-HSA-9828806 4.660540e-02 1.332 0 0
PIP3 activates AKT signaling R-HSA-1257604 4.706517e-02 1.327 0 0
Axonal growth stimulation R-HSA-209563 5.053987e-02 1.296 0 0
Invadopodia formation R-HSA-8941237 5.053987e-02 1.296 0 0
MET interacts with TNS proteins R-HSA-8875513 5.053987e-02 1.296 0 0
Phase 0 - rapid depolarisation R-HSA-5576892 4.914529e-02 1.309 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 5.437111e-02 1.265 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 5.173429e-02 1.286 0 0
DAP12 signaling R-HSA-2424491 5.437111e-02 1.265 0 0
Respiratory electron transport R-HSA-611105 5.548558e-02 1.256 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 5.705451e-02 1.244 0 0
Nervous system development R-HSA-9675108 5.055601e-02 1.296 1 0
Host Interactions of HIV factors R-HSA-162909 5.651272e-02 1.248 0 0
Interleukin-37 signaling R-HSA-9008059 5.437111e-02 1.265 0 0
Interleukin-12 signaling R-HSA-9020591 5.772004e-02 1.239 0 0
FBXW7 Mutants and NOTCH1 in Cancer R-HSA-2644605 6.033892e-02 1.219 0 0
Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling R-HSA-2644607 6.033892e-02 1.219 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 6.033892e-02 1.219 0 0
Defective CP causes aceruloplasminemia (ACERULOP) R-HSA-5619060 6.033892e-02 1.219 0 0
MDK and PTN in ALK signaling R-HSA-9851151 6.033892e-02 1.219 0 0
TNFR1-mediated ceramide production R-HSA-5626978 6.033892e-02 1.219 0 0
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB R-HSA-9673768 7.003744e-02 1.155 0 0
Noncanonical activation of NOTCH3 R-HSA-9017802 7.963645e-02 1.099 0 0
Defective CSF2RA causes SMDP4 R-HSA-5688890 7.963645e-02 1.099 0 0
Defective CSF2RB causes SMDP5 R-HSA-5688849 7.963645e-02 1.099 0 0
Erythropoietin activates STAT5 R-HSA-9027283 8.913696e-02 1.050 0 0
IFNG signaling activates MAPKs R-HSA-9732724 9.853999e-02 1.006 0 0
Formation of annular gap junctions R-HSA-196025 1.078465e-01 0.967 0 0
Activated NTRK2 signals through PI3K R-HSA-9028335 1.078465e-01 0.967 0 0
Interleukin-21 signaling R-HSA-9020958 1.170575e-01 0.932 0 0
Gap junction degradation R-HSA-190873 1.170575e-01 0.932 0 0
Erythropoietin activates Phospholipase C gamma (PLCG) R-HSA-9027277 1.261740e-01 0.899 0 0
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 R-HSA-5140745 1.261740e-01 0.899 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 1.441273e-01 0.841 0 0
Signaling by CSF1 (M-CSF) in myeloid cells R-HSA-9680350 6.822964e-02 1.166 0 0
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8854050 7.112790e-02 1.148 0 0
PI-3K cascade:FGFR3 R-HSA-5654710 2.204850e-01 0.657 0 0
Degradation of CRY and PER proteins R-HSA-9932298 9.246083e-02 1.034 0 0
PI-3K cascade:FGFR4 R-HSA-5654720 2.285396e-01 0.641 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 2.285396e-01 0.641 0 0
PI-3K cascade:FGFR1 R-HSA-5654689 2.522103e-01 0.598 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 2.675882e-01 0.573 0 0
PI-3K cascade:FGFR2 R-HSA-5654695 2.751588e-01 0.560 0 0
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.756670e-01 0.755 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 2.549615e-01 0.594 0 0
Amplification of signal from the kinetochores R-HSA-141424 2.549615e-01 0.594 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 2.041243e-01 0.690 0 0
Role of LAT2/NTAL/LAB on calcium mobilization R-HSA-2730905 3.046422e-01 0.516 0 0
Neutrophil degranulation R-HSA-6798695 1.257642e-01 0.900 0 0
Signaling by Leptin R-HSA-2586552 1.261740e-01 0.899 0 0
Interleukin-35 Signalling R-HSA-8984722 1.529659e-01 0.815 0 0
EPHB-mediated forward signaling R-HSA-3928662 1.021057e-01 0.991 1 1
Vif-mediated degradation of APOBEC3G R-HSA-180585 7.406567e-02 1.130 0 0
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 R-HSA-9762114 7.704183e-02 1.113 0 0
RNA Polymerase I Transcription Termination R-HSA-73863 2.900676e-01 0.538 0 0
EPH-Ephrin signaling R-HSA-2682334 9.065417e-02 1.043 1 0
Signaling by RAF1 mutants R-HSA-9656223 9.246083e-02 1.034 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.086831e-01 0.964 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.086831e-01 0.964 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.086831e-01 0.964 0 0
Neddylation R-HSA-8951664 1.072181e-01 0.970 0 0
Interleukin-6 signaling R-HSA-1059683 1.617138e-01 0.791 0 0
Interleukin-6 family signaling R-HSA-6783589 2.675882e-01 0.573 0 0
Interleukin-23 signaling R-HSA-9020933 1.078465e-01 0.967 0 0
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 R-HSA-450321 2.365114e-01 0.626 0 0
IL-6-type cytokine receptor ligand interactions R-HSA-6788467 1.617138e-01 0.791 0 0
Oncogenic MAPK signaling R-HSA-6802957 2.511374e-01 0.600 0 0
NGF-stimulated transcription R-HSA-9031628 1.153699e-01 0.938 0 0
Processing of SMDT1 R-HSA-8949664 1.617138e-01 0.791 0 0
Nuclear RNA decay R-HSA-9930044 6.255616e-02 1.204 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 9.250613e-02 1.034 0 0
Degradation of DVL R-HSA-4641258 7.704183e-02 1.113 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 8.310496e-02 1.080 0 0
Disassembly of the destruction complex and recruitment of AXIN to the membrane R-HSA-4641262 2.900676e-01 0.538 0 0
Signaling by RAS mutants R-HSA-6802949 1.086831e-01 0.964 0 0
Inactivation of CSF3 (G-CSF) signaling R-HSA-9705462 2.444014e-01 0.612 0 0
Complex IV assembly R-HSA-9864848 1.255893e-01 0.901 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.585914e-02 1.018 0 0
Ribosome-associated quality control R-HSA-9948299 2.180771e-01 0.661 0 0
Interleukin-10 signaling R-HSA-6783783 6.104254e-02 1.214 0 0
Signaling by CSF3 (G-CSF) R-HSA-9674555 3.046715e-01 0.516 0 0
Leishmania phagocytosis R-HSA-9664417 8.179752e-02 1.087 0 0
Parasite infection R-HSA-9664407 8.179752e-02 1.087 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 8.179752e-02 1.087 0 0
Co-stimulation by ICOS R-HSA-9927354 1.078465e-01 0.967 0 0
p75NTR regulates axonogenesis R-HSA-193697 1.170575e-01 0.932 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 1.529659e-01 0.815 0 0
Acetylation R-HSA-156582 1.529659e-01 0.815 0 0
Antigen processing: Ub, ATP-independent proteasomal degradation R-HSA-9912633 1.958164e-01 0.708 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 8.930876e-02 1.049 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 9.246083e-02 1.034 0 0
Orc1 removal from chromatin R-HSA-68949 1.290427e-01 0.889 0 0
Cristae formation R-HSA-8949613 2.900676e-01 0.538 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 9.267343e-02 1.033 0 0
Complex I biogenesis R-HSA-6799198 1.683178e-01 0.774 0 0
Nuclear Events (kinase and transcription factor activation) R-HSA-198725 2.017518e-01 0.695 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 8.326113e-02 1.080 1 1
Signaling by cytosolic FGFR1 fusion mutants R-HSA-1839117 2.123469e-01 0.673 0 0
Asymmetric localization of PCP proteins R-HSA-4608870 1.053803e-01 0.977 0 0
Interleukin-12 family signaling R-HSA-447115 7.894090e-02 1.103 0 0
Activated NTRK3 signals through PI3K R-HSA-9603381 9.853999e-02 1.006 0 0
MET activates PI3K/AKT signaling R-HSA-8851907 9.853999e-02 1.006 0 0
Interleukin-27 signaling R-HSA-9020956 1.261740e-01 0.899 0 0
PI3K/AKT activation R-HSA-198203 1.261740e-01 0.899 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 9.246083e-02 1.034 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 9.246083e-02 1.034 0 0
Regulation of RAS by GAPs R-HSA-5658442 1.221587e-01 0.913 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 2.974073e-01 0.527 0 0
Separation of Sister Chromatids R-HSA-2467813 2.927231e-01 0.534 0 0
Proteasome assembly R-HSA-9907900 1.021057e-01 0.991 0 0
FCERI mediated MAPK activation R-HSA-2871796 1.390358e-01 0.857 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 1.018097e-01 0.992 0 0
VEGF binds to VEGFR leading to receptor dimerization R-HSA-195399 7.963645e-02 1.099 0 0
Axonal growth inhibition (RHOA activation) R-HSA-193634 1.078465e-01 0.967 0 0
Astrocytic Glutamate-Glutamine Uptake And Metabolism R-HSA-210455 1.078465e-01 0.967 0 0
Neurotransmitter uptake and metabolism In glial cells R-HSA-112313 1.078465e-01 0.967 0 0
MAPK1 (ERK2) activation R-HSA-112411 1.170575e-01 0.932 0 0
RHOBTB3 ATPase cycle R-HSA-9706019 1.351970e-01 0.869 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 8.618980e-02 1.065 0 0
Recognition of DNA damage by PCNA-containing replication complex R-HSA-110314 2.675882e-01 0.573 0 0
Tight junction interactions R-HSA-420029 2.751588e-01 0.560 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 1.117408e-01 0.952 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 2.549615e-01 0.594 0 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 2.675882e-01 0.573 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 3.008328e-01 0.522 0 0
Downstream signaling of activated FGFR3 R-HSA-5654708 3.046715e-01 0.516 0 0
Mitochondrial calcium ion transport R-HSA-8949215 2.444014e-01 0.612 0 0
Switching of origins to a post-replicative state R-HSA-69052 2.055161e-01 0.687 0 0
Diseases associated with surfactant metabolism R-HSA-5687613 1.529659e-01 0.815 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 6.898706e-02 1.161 0 0
Co-inhibition by BTLA R-HSA-9927353 7.003744e-02 1.155 0 0
VEGF ligand-receptor interactions R-HSA-194313 7.963645e-02 1.099 0 0
Signaling by LTK in cancer R-HSA-9842640 8.913696e-02 1.050 0 0
MAPK3 (ERK1) activation R-HSA-110056 1.261740e-01 0.899 0 0
Cholesterol biosynthesis via desmosterol R-HSA-6807047 1.351970e-01 0.869 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 1.529659e-01 0.815 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 1.529659e-01 0.815 0 0
Regulation of BACH1 activity R-HSA-9708530 1.874223e-01 0.727 0 0
Synthesis of 15-eicosatetraenoic acid derivatives R-HSA-2142770 2.041243e-01 0.690 0 0
Deadenylation of mRNA R-HSA-429947 2.675882e-01 0.573 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 2.751588e-01 0.560 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 1.863231e-01 0.730 0 0
DAP12 interactions R-HSA-2172127 1.021057e-01 0.991 0 0
Generation of second messenger molecules R-HSA-202433 8.618980e-02 1.065 0 0
PCP/CE pathway R-HSA-4086400 2.244421e-01 0.649 0 0
Nef and signal transduction R-HSA-164944 8.913696e-02 1.050 0 0
Signaling by FGFR4 in disease R-HSA-5655291 1.703719e-01 0.769 0 0
Formation of the active cofactor, UDP-glucuronate R-HSA-173599 1.703719e-01 0.769 0 0
Synthesis of PG R-HSA-1483148 1.958164e-01 0.708 0 0
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters R-HSA-164938 2.041243e-01 0.690 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 8.930876e-02 1.049 0 0
Degradation of CDH1 R-HSA-9766229 1.187520e-01 0.925 0 0
Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives R-HSA-9027604 2.751588e-01 0.560 0 0
TNFR1-induced NF-kappa-B signaling pathway R-HSA-5357956 2.900676e-01 0.538 0 0
GAB1 signalosome R-HSA-180292 2.123469e-01 0.673 0 0
Signal transduction by L1 R-HSA-445144 2.285396e-01 0.641 0 0
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A R-HSA-69601 1.053803e-01 0.977 0 0
p53-Independent G1/S DNA Damage Checkpoint R-HSA-69613 1.053803e-01 0.977 0 0
Signaling by NTRKs R-HSA-166520 2.480881e-01 0.605 0 0
Other interleukin signaling R-HSA-449836 2.204850e-01 0.657 0 0
Regulation of RUNX2 expression and activity R-HSA-8939902 1.610241e-01 0.793 0 0
Metabolism of RNA R-HSA-8953854 2.759109e-01 0.559 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 1.001961e-01 0.999 0 0
Cellular response to mitochondrial stress R-HSA-9840373 1.170575e-01 0.932 0 0
Physiological factors R-HSA-5578768 1.703719e-01 0.769 0 0
Modulation of host responses by IFN-stimulated genes R-HSA-9909505 2.041243e-01 0.690 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 2.522103e-01 0.598 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 2.320515e-01 0.634 0 0
Transcriptional Regulation by VENTX R-HSA-8853884 8.930876e-02 1.049 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 1.741405e-01 0.759 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 2.434914e-01 0.614 0 0
PECAM1 interactions R-HSA-210990 1.351970e-01 0.869 0 0
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) R-HSA-400511 1.958164e-01 0.708 0 0
NRAGE signals death through JNK R-HSA-193648 1.430697e-01 0.844 0 0
Synthesis of IP2, IP, and Ins in the cytosol R-HSA-1855183 2.826517e-01 0.549 0 0
Signaling by FGFR3 in disease R-HSA-5655332 2.900676e-01 0.538 0 0
Potential therapeutics for SARS R-HSA-9679191 9.859461e-02 1.006 0 0
Glycogen synthesis R-HSA-3322077 2.285396e-01 0.641 0 0
Cytoprotection by HMOX1 R-HSA-9707564 6.972912e-02 1.157 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 2.522103e-01 0.598 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 1.942487e-01 0.712 0 0
Circadian clock R-HSA-9909396 1.994070e-01 0.700 0 0
Platelet activation, signaling and aggregation R-HSA-76002 8.706265e-02 1.060 0 0
Caspase activation via Dependence Receptors in the absence of ligand R-HSA-418889 1.170575e-01 0.932 0 0
MAP3K8 (TPL2)-dependent MAPK1/3 activation R-HSA-5684264 1.703719e-01 0.769 0 0
Regulation of KIT signaling R-HSA-1433559 1.703719e-01 0.769 0 0
Synthesis, secretion, and deacylation of Ghrelin R-HSA-422085 2.365114e-01 0.626 0 0
Downstream TCR signaling R-HSA-202424 2.740927e-01 0.562 0 0
Amyloid fiber formation R-HSA-977225 2.358625e-01 0.627 0 0
Signaling by ROBO receptors R-HSA-376176 2.001289e-01 0.699 0 0
Muscle contraction R-HSA-397014 2.216246e-01 0.654 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.170575e-01 0.932 0 0
p75NTR recruits signalling complexes R-HSA-209543 1.529659e-01 0.815 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 2.041243e-01 0.690 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 2.041243e-01 0.690 0 0
Platelet sensitization by LDL R-HSA-432142 2.123469e-01 0.673 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 2.826517e-01 0.549 0 0
Hedgehog 'on' state R-HSA-5632684 1.979958e-01 0.703 0 0
Signaling by NTRK3 (TRKC) R-HSA-9034015 2.444014e-01 0.612 0 0
Disease R-HSA-1643685 2.735287e-01 0.563 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.170575e-01 0.932 0 0
Signaling by LTK R-HSA-9842663 1.529659e-01 0.815 0 0
Signal regulatory protein family interactions R-HSA-391160 1.703719e-01 0.769 0 0
Signaling by Hippo R-HSA-2028269 2.041243e-01 0.690 0 0
Glycogen storage diseases R-HSA-3229121 2.041243e-01 0.690 0 0
Basigin interactions R-HSA-210991 2.365114e-01 0.626 0 0
Carnitine shuttle R-HSA-200425 2.599389e-01 0.585 0 0
Complex III assembly R-HSA-9865881 2.675882e-01 0.573 0 0
Signaling by NOTCH4 R-HSA-9013694 2.092880e-01 0.679 0 0
Cytosolic tRNA aminoacylation R-HSA-379716 9.564500e-02 1.019 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.826517e-01 0.549 0 0
Cholesterol biosynthesis via lathosterol R-HSA-6807062 2.522103e-01 0.598 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 1.646637e-01 0.783 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 1.683178e-01 0.774 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 2.365114e-01 0.626 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 2.365114e-01 0.626 0 0
RET signaling R-HSA-8853659 7.406567e-02 1.130 0 0
Signaling by FLT3 ITD and TKD mutants R-HSA-9703648 2.675882e-01 0.573 0 0
DARPP-32 events R-HSA-180024 3.046715e-01 0.516 0 0
Cellular responses to stimuli R-HSA-8953897 1.541513e-01 0.812 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 7.748464e-02 1.111 0 0
p75NTR signals via NF-kB R-HSA-193639 1.789410e-01 0.747 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 8.310496e-02 1.080 0 0
Interleukin-7 signaling R-HSA-1266695 2.751588e-01 0.560 0 0
Synthesis of PIPs at the early endosome membrane R-HSA-1660516 2.751588e-01 0.560 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 2.511374e-01 0.600 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 2.522103e-01 0.598 0 0
Innate Immune System R-HSA-168249 2.363581e-01 0.626 1 0
Interleukin-1 signaling R-HSA-9020702 1.116577e-01 0.952 0 0
G alpha (12/13) signalling events R-HSA-416482 2.244421e-01 0.649 0 0
Cell surface interactions at the vascular wall R-HSA-202733 2.776696e-01 0.556 0 0
Cardiac conduction R-HSA-5576891 1.967723e-01 0.706 0 0
Signaling by EGFR R-HSA-177929 1.430697e-01 0.844 0 0
Caspase activation via extrinsic apoptotic signalling pathway R-HSA-5357769 2.826517e-01 0.549 0 0
Biosynthesis of EPA-derived SPMs R-HSA-9018679 3.046715e-01 0.516 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 2.055161e-01 0.687 0 0
Signaling by MET R-HSA-6806834 2.320515e-01 0.634 0 0
Amino acid transport across the plasma membrane R-HSA-352230 1.537915e-01 0.813 0 0
Azathioprine ADME R-HSA-9748787 1.221587e-01 0.913 0 0
Biosynthesis of DPAn-3 SPMs R-HSA-9025094 2.900676e-01 0.538 0 0
SLC-mediated transport of amino acids R-HSA-9958863 1.830665e-01 0.737 0 0
L1CAM interactions R-HSA-373760 1.535002e-01 0.814 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 1.401965e-01 0.853 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 1.401965e-01 0.853 0 0
Signaling by NTRK2 (TRKB) R-HSA-9006115 2.900676e-01 0.538 0 0
Uptake and function of anthrax toxins R-HSA-5210891 2.041243e-01 0.690 0 0
HIV Infection R-HSA-162906 2.549227e-01 0.594 0 0
Dissolution of Fibrin Clot R-HSA-75205 1.351970e-01 0.869 0 0
Replication of the SARS-CoV-1 genome R-HSA-9682706 1.617138e-01 0.791 0 0
tRNA Aminoacylation R-HSA-379724 1.573998e-01 0.803 0 0
Replication of the SARS-CoV-2 genome R-HSA-9694686 2.041243e-01 0.690 0 0
Intracellular signaling by second messengers R-HSA-9006925 8.433619e-02 1.074 0 0
Signaling by NOTCH R-HSA-157118 2.845603e-01 0.546 0 0
Cell-cell junction organization R-HSA-421270 1.523694e-01 0.817 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.854849e-01 0.732 0 0
SARS-CoV-1 Genome Replication and Transcription R-HSA-9679514 1.703719e-01 0.769 0 0
Cell junction organization R-HSA-446728 1.986819e-01 0.702 0 0
SARS-CoV-2 Genome Replication and Transcription R-HSA-9694682 2.204850e-01 0.657 0 0
Adherens junctions interactions R-HSA-418990 2.348074e-01 0.629 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.756670e-01 0.755 0 0
Programmed Cell Death R-HSA-5357801 8.629723e-02 1.064 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 3.084480e-01 0.511 0 0
Downstream signaling of activated FGFR4 R-HSA-5654716 3.118611e-01 0.506 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.118611e-01 0.506 0 0
Adaptive Immune System R-HSA-1280218 3.148704e-01 0.502 0 0
FOXO-mediated transcription R-HSA-9614085 3.160470e-01 0.500 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 3.189767e-01 0.496 0 0
Biosynthesis of DPA-derived SPMs R-HSA-9018683 3.189767e-01 0.496 0 0
EGFR downregulation R-HSA-182971 3.189767e-01 0.496 0 0
Mitotic Spindle Checkpoint R-HSA-69618 3.198398e-01 0.495 0 0
Hedgehog 'off' state R-HSA-5610787 3.198398e-01 0.495 0 0
Glycolysis R-HSA-70171 3.198398e-01 0.495 0 0
Translation R-HSA-72766 3.249651e-01 0.488 0 0
Hemostasis R-HSA-109582 3.252361e-01 0.488 0 0
Regulation of ornithine decarboxylase (ODC) R-HSA-350562 3.260193e-01 0.487 0 0
HS-GAG degradation R-HSA-2024096 3.260193e-01 0.487 0 0
Cell Cycle Checkpoints R-HSA-69620 3.263557e-01 0.486 0 0
PI Metabolism R-HSA-1483255 3.274100e-01 0.485 0 0
FGFR1 mutant receptor activation R-HSA-1839124 3.329894e-01 0.478 0 0
Response of endothelial cells to shear stress R-HSA-9860931 3.349580e-01 0.475 0 0
RSV-host interactions R-HSA-9833110 3.387230e-01 0.470 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 3.398879e-01 0.469 0 0
Vpu mediated degradation of CD4 R-HSA-180534 3.398879e-01 0.469 0 0
Regulation of CDH1 posttranslational processing and trafficking to plasma membrane R-HSA-9768727 3.398879e-01 0.469 0 0
Heme degradation R-HSA-189483 3.398879e-01 0.469 0 0
G alpha (q) signalling events R-HSA-416476 3.403973e-01 0.468 0 0
Dual Incision in GG-NER R-HSA-5696400 3.467155e-01 0.460 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 3.467155e-01 0.460 0 0
Mitophagy R-HSA-5205647 3.467155e-01 0.460 0 0
Ubiquitin-dependent degradation of Cyclin D R-HSA-75815 3.467155e-01 0.460 0 0
Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-349425 3.467155e-01 0.460 0 0
RAF activation R-HSA-5673000 3.467155e-01 0.460 0 0
TCF dependent signaling in response to WNT R-HSA-201681 3.491473e-01 0.457 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 3.499785e-01 0.456 0 0
Synthesis of DNA R-HSA-69239 3.499785e-01 0.456 0 0
SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174113 3.534728e-01 0.452 0 0
Downstream signaling of activated FGFR2 R-HSA-5654696 3.534728e-01 0.452 0 0
Downstream signaling of activated FGFR1 R-HSA-5654687 3.534728e-01 0.452 0 0
PERK regulates gene expression R-HSA-381042 3.534728e-01 0.452 0 0
Regulation of Apoptosis R-HSA-169911 3.534728e-01 0.452 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 3.534728e-01 0.452 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 3.574467e-01 0.447 0 0
G2/M Transition R-HSA-69275 3.575996e-01 0.447 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 3.601607e-01 0.444 0 0
FLT3 signaling in disease R-HSA-9682385 3.601607e-01 0.444 0 0
Triglyceride catabolism R-HSA-163560 3.601607e-01 0.444 0 0
Mitotic G2-G2/M phases R-HSA-453274 3.632268e-01 0.440 0 0
Voltage gated Potassium channels R-HSA-1296072 3.667798e-01 0.436 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 3.667798e-01 0.436 0 0
Degradation of AXIN R-HSA-4641257 3.667798e-01 0.436 0 0
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription R-HSA-2173796 3.667798e-01 0.436 0 0
Metabolism of folate and pterines R-HSA-196757 3.667798e-01 0.436 0 0
MET promotes cell motility R-HSA-8875878 3.733308e-01 0.428 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 3.759789e-01 0.425 0 0
Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-1236978 3.798145e-01 0.420 0 0
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) R-HSA-381771 3.798145e-01 0.420 0 0
Stabilization of p53 R-HSA-69541 3.798145e-01 0.420 0 0
Parasitic Infection Pathways R-HSA-9824443 3.802392e-01 0.420 0 0
Leishmania infection R-HSA-9658195 3.802392e-01 0.420 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 3.833316e-01 0.416 0 0
Formation of Incision Complex in GG-NER R-HSA-5696395 3.862315e-01 0.413 0 0
Regulation of RUNX3 expression and activity R-HSA-8941858 3.862315e-01 0.413 0 0
Glycogen metabolism R-HSA-8982491 3.862315e-01 0.413 0 0
FCERI mediated Ca+2 mobilization R-HSA-2871809 3.869942e-01 0.412 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 3.869942e-01 0.412 0 0
SARS-CoV Infections R-HSA-9679506 3.893521e-01 0.410 0 0
Hh mutants are degraded by ERAD R-HSA-5362768 3.925825e-01 0.406 0 0
NIK-->noncanonical NF-kB signaling R-HSA-5676590 3.925825e-01 0.406 0 0
FLT3 Signaling R-HSA-9607240 3.925825e-01 0.406 0 0
PKMTs methylate histone lysines R-HSA-3214841 3.925825e-01 0.406 0 0
Cellular responses to stress R-HSA-2262752 3.929644e-01 0.406 0 0
Glucose metabolism R-HSA-70326 3.942910e-01 0.404 0 0
Co-inhibition by PD-1 R-HSA-389948 3.967998e-01 0.401 0 0
MAP2K and MAPK activation R-HSA-5674135 3.988681e-01 0.399 0 0
Signaling by FGFR1 in disease R-HSA-5655302 3.988681e-01 0.399 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 4.015485e-01 0.396 0 0
RNA Polymerase I Transcription Initiation R-HSA-73762 4.050891e-01 0.392 0 0
Incretin synthesis, secretion, and inactivation R-HSA-400508 4.050891e-01 0.392 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.087653e-01 0.389 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 4.087653e-01 0.389 0 0
Signaling by FGFR4 R-HSA-5654743 4.112461e-01 0.386 0 0
Hh mutants abrogate ligand secretion R-HSA-5387390 4.112461e-01 0.386 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 4.112461e-01 0.386 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 4.159400e-01 0.381 0 0
Gap junction trafficking R-HSA-190828 4.173397e-01 0.380 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 4.173397e-01 0.380 0 0
Surfactant metabolism R-HSA-5683826 4.173397e-01 0.380 0 0
Cyclin D associated events in G1 R-HSA-69231 4.173397e-01 0.380 0 0
G1 Phase R-HSA-69236 4.173397e-01 0.380 0 0
RMTs methylate histone arginines R-HSA-3214858 4.173397e-01 0.380 0 0
Formation of the cornified envelope R-HSA-6809371 4.195112e-01 0.377 0 0
Signaling by FGFR3 R-HSA-5654741 4.233707e-01 0.373 0 0
Defective CFTR causes cystic fibrosis R-HSA-5678895 4.233707e-01 0.373 0 0
Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607761 4.233707e-01 0.373 0 0
Somitogenesis R-HSA-9824272 4.233707e-01 0.373 0 0
mRNA Splicing - Minor Pathway R-HSA-72165 4.293396e-01 0.367 0 0
Formation of TC-NER Pre-Incision Complex R-HSA-6781823 4.293396e-01 0.367 0 0
Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174084 4.293396e-01 0.367 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 4.293396e-01 0.367 0 0
Regulation of TNFR1 signaling R-HSA-5357905 4.293396e-01 0.367 0 0
Platelet degranulation R-HSA-114608 4.336841e-01 0.363 0 0
APC/C:Cdc20 mediated degradation of Securin R-HSA-174154 4.352471e-01 0.361 0 0
Metal ion SLC transporters R-HSA-425410 4.410937e-01 0.355 0 0
Gluconeogenesis R-HSA-70263 4.410937e-01 0.355 0 0
Mitotic Anaphase R-HSA-68882 4.435042e-01 0.353 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 4.462107e-01 0.350 0 0
Gap junction trafficking and regulation R-HSA-157858 4.468803e-01 0.350 0 0
NOTCH1 Intracellular Domain Regulates Transcription R-HSA-2122947 4.468803e-01 0.350 0 0
DNA Damage Bypass R-HSA-73893 4.468803e-01 0.350 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 4.468803e-01 0.350 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 4.468803e-01 0.350 0 0
Drug ADME R-HSA-9748784 4.489121e-01 0.348 0 0
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) R-HSA-2162123 4.526072e-01 0.344 0 0
PI3K Cascade R-HSA-109704 4.526072e-01 0.344 0 0
Signaling by FGFR2 in disease R-HSA-5655253 4.526072e-01 0.344 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 4.580353e-01 0.339 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 4.582752e-01 0.339 0 0
Hedgehog ligand biogenesis R-HSA-5358346 4.582752e-01 0.339 0 0
mRNA 3'-end processing R-HSA-72187 4.638849e-01 0.334 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 4.638849e-01 0.334 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 4.638849e-01 0.334 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 4.638849e-01 0.334 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 4.638849e-01 0.334 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 4.694368e-01 0.328 0 0
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174178 4.694368e-01 0.328 0 0
Smooth Muscle Contraction R-HSA-445355 4.694368e-01 0.328 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 4.694368e-01 0.328 0 0
Regulation of PTEN stability and activity R-HSA-8948751 4.694368e-01 0.328 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 4.716785e-01 0.326 0 0
Translation initiation complex formation R-HSA-72649 4.749316e-01 0.323 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 4.749316e-01 0.323 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 4.749316e-01 0.323 0 0
Glucuronidation R-HSA-156588 4.749316e-01 0.323 0 0
SARS-CoV-2-host interactions R-HSA-9705683 4.756252e-01 0.323 0 0
Signaling by Hedgehog R-HSA-5358351 4.784232e-01 0.320 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 4.803698e-01 0.318 0 0
G alpha (z) signalling events R-HSA-418597 4.803698e-01 0.318 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 4.803698e-01 0.318 0 0
Paracetamol ADME R-HSA-9753281 4.803698e-01 0.318 0 0
Signaling by NOTCH3 R-HSA-9012852 4.803698e-01 0.318 0 0
PTEN Regulation R-HSA-6807070 4.817759e-01 0.317 0 0
Gap-filling DNA repair synthesis and ligation in TC-NER R-HSA-6782210 4.857520e-01 0.314 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 4.857520e-01 0.314 0 0
Signaling by FGFR1 R-HSA-5654736 4.857520e-01 0.314 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 4.857520e-01 0.314 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 4.857520e-01 0.314 0 0
TNF signaling R-HSA-75893 4.857520e-01 0.314 0 0
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer R-HSA-2173793 4.857520e-01 0.314 0 0
IRS-mediated signalling R-HSA-112399 4.910788e-01 0.309 0 0
Synthesis of PA R-HSA-1483166 4.910788e-01 0.309 0 0
Chromatin modifying enzymes R-HSA-3247509 4.913691e-01 0.309 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 4.950544e-01 0.305 0 0
Dual incision in TC-NER R-HSA-6782135 4.963508e-01 0.304 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 4.963508e-01 0.304 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 4.963508e-01 0.304 0 0
Clathrin-mediated endocytosis R-HSA-8856828 4.983404e-01 0.302 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 5.015684e-01 0.300 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 5.015684e-01 0.300 0 0
Triglyceride metabolism R-HSA-8979227 5.015684e-01 0.300 0 0
Regulation of PTEN gene transcription R-HSA-8943724 5.067324e-01 0.295 0 0
Metabolism of polyamines R-HSA-351202 5.067324e-01 0.295 0 0
Signaling by NOTCH1 in Cancer R-HSA-2644603 5.067324e-01 0.295 0 0
Signaling by NOTCH1 PEST Domain Mutants in Cancer R-HSA-2644602 5.067324e-01 0.295 0 0
Constitutive Signaling by NOTCH1 PEST Domain Mutants R-HSA-2644606 5.067324e-01 0.295 0 0
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants R-HSA-2894862 5.067324e-01 0.295 0 0
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer R-HSA-2894858 5.067324e-01 0.295 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 5.081169e-01 0.294 0 0
ER to Golgi Anterograde Transport R-HSA-199977 5.113482e-01 0.291 0 0
RNA Polymerase II Transcription Termination R-HSA-73856 5.118431e-01 0.291 0 0
IRS-related events triggered by IGF1R R-HSA-2428928 5.118431e-01 0.291 0 0
MAP kinase activation R-HSA-450294 5.118431e-01 0.291 0 0
Formation of paraxial mesoderm R-HSA-9793380 5.118431e-01 0.291 0 0
S Phase R-HSA-69242 5.145657e-01 0.289 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 5.169012e-01 0.287 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 5.169012e-01 0.287 0 0
Mitochondrial protein import R-HSA-1268020 5.169012e-01 0.287 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 5.219072e-01 0.282 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 5.219072e-01 0.282 0 0
Signaling by PTK6 R-HSA-8848021 5.219072e-01 0.282 0 0
CD22 mediated BCR regulation R-HSA-5690714 5.268617e-01 0.278 0 0
IGF1R signaling cascade R-HSA-2428924 5.268617e-01 0.278 0 0
Insulin receptor signalling cascade R-HSA-74751 5.268617e-01 0.278 0 0
Chromatin organization R-HSA-4839726 5.296851e-01 0.276 0 0
DNA Replication R-HSA-69306 5.304437e-01 0.275 0 0
Viral Infection Pathways R-HSA-9824446 5.314418e-01 0.275 0 0
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) R-HSA-2404192 5.317651e-01 0.274 0 0
SARS-CoV-2 Infection R-HSA-9694516 5.339339e-01 0.273 0 0
AURKA Activation by TPX2 R-HSA-8854518 5.366179e-01 0.270 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 5.461742e-01 0.263 0 0
Signaling by TGFB family members R-HSA-9006936 5.520773e-01 0.258 0 0
COPII-mediated vesicle transport R-HSA-204005 5.555346e-01 0.255 0 0
Interleukin-17 signaling R-HSA-448424 5.555346e-01 0.255 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 5.555346e-01 0.255 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 5.555346e-01 0.255 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 5.601426e-01 0.252 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 5.601426e-01 0.252 0 0
Regulation of mitotic cell cycle R-HSA-453276 5.601426e-01 0.252 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 5.601426e-01 0.252 0 0
Metabolism of porphyrins R-HSA-189445 5.601426e-01 0.252 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 5.647030e-01 0.248 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 5.647030e-01 0.248 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 5.692165e-01 0.245 0 0
Ca2+ pathway R-HSA-4086398 5.692165e-01 0.245 0 0
Diseases of carbohydrate metabolism R-HSA-5663084 5.692165e-01 0.245 0 0
Cell Cycle, Mitotic R-HSA-69278 5.714922e-01 0.243 0 0
Signaling by FGFR in disease R-HSA-1226099 5.736835e-01 0.241 0 0
Signaling by ERBB4 R-HSA-1236394 5.736835e-01 0.241 0 0
Transcription-Coupled Nucleotide Excision Repair (TC-NER) R-HSA-6781827 5.781044e-01 0.238 0 0
Iron uptake and transport R-HSA-917937 5.781044e-01 0.238 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 5.824797e-01 0.235 0 0
UCH proteinases R-HSA-5689603 5.824797e-01 0.235 0 0
Signaling by NOTCH1 R-HSA-1980143 5.824797e-01 0.235 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 5.846430e-01 0.233 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 5.903744e-01 0.229 0 0
RNA Polymerase I Transcription R-HSA-73864 5.910955e-01 0.228 0 0
Cholesterol biosynthesis R-HSA-191273 5.910955e-01 0.228 0 0
ABC transporter disorders R-HSA-5619084 5.910955e-01 0.228 0 0
Integrin cell surface interactions R-HSA-216083 5.910955e-01 0.228 0 0
Sensory processing of sound R-HSA-9659379 5.953369e-01 0.225 0 0
SARS-CoV-1 Infection R-HSA-9678108 5.988618e-01 0.223 0 0
Signaling by FGFR2 R-HSA-5654738 5.995345e-01 0.222 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 5.995345e-01 0.222 0 0
Biosynthesis of DHA-derived SPMs R-HSA-9018677 6.036889e-01 0.219 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 6.078005e-01 0.216 0 0
TNFR2 non-canonical NF-kB pathway R-HSA-5668541 6.118696e-01 0.213 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 6.158967e-01 0.210 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 6.158967e-01 0.210 0 0
RNA polymerase II transcribes snRNA genes R-HSA-6807505 6.277307e-01 0.202 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 6.277307e-01 0.202 0 0
Peptide ligand-binding receptors R-HSA-375276 6.288555e-01 0.201 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 6.341192e-01 0.198 0 0
Peptide chain elongation R-HSA-156902 6.354180e-01 0.197 0 0
Selective autophagy R-HSA-9663891 6.354180e-01 0.197 0 0
Phospholipid metabolism R-HSA-1483257 6.364054e-01 0.196 0 0
ER-Phagosome pathway R-HSA-1236974 6.392022e-01 0.194 0 0
Signaling by WNT R-HSA-195721 6.427528e-01 0.192 0 0
Class B/2 (Secretin family receptors) R-HSA-373080 6.429474e-01 0.192 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 6.466539e-01 0.189 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 6.466539e-01 0.189 0 0
Mitotic Prometaphase R-HSA-68877 6.470246e-01 0.189 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 6.503222e-01 0.187 0 0
G alpha (i) signalling events R-HSA-418594 6.505906e-01 0.187 0 0
Eukaryotic Translation Elongation R-HSA-156842 6.539527e-01 0.184 0 0
Signaling by Insulin receptor R-HSA-74752 6.539527e-01 0.184 0 0
Assembly of the pre-replicative complex R-HSA-68867 6.575457e-01 0.182 0 0
Mitochondrial protein degradation R-HSA-9837999 6.611015e-01 0.180 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 6.646207e-01 0.177 0 0
Formation of a pool of free 40S subunits R-HSA-72689 6.681036e-01 0.175 0 0
Eukaryotic Translation Termination R-HSA-72764 6.681036e-01 0.175 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 6.693482e-01 0.174 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 6.715505e-01 0.173 0 0
COPI-mediated anterograde transport R-HSA-6807878 6.715505e-01 0.173 0 0
Potassium Channels R-HSA-1296071 6.715505e-01 0.173 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 6.715505e-01 0.173 0 0
Transcriptional regulation by RUNX3 R-HSA-8878159 6.749618e-01 0.171 0 0
Signaling by FGFR R-HSA-190236 6.783379e-01 0.169 0 0
MyD88 cascade initiated on plasma membrane R-HSA-975871 6.783379e-01 0.169 0 0
Toll Like Receptor 5 (TLR5) Cascade R-HSA-168176 6.783379e-01 0.169 0 0
Toll Like Receptor 10 (TLR10) Cascade R-HSA-168142 6.783379e-01 0.169 0 0
Keratinization R-HSA-6805567 6.812530e-01 0.167 0 0
ABC-family proteins mediated transport R-HSA-382556 6.849859e-01 0.164 0 0
Selenocysteine synthesis R-HSA-2408557 6.882585e-01 0.162 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 6.882585e-01 0.162 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 6.914973e-01 0.160 0 0
Viral mRNA Translation R-HSA-192823 6.947026e-01 0.158 0 0
Signaling by GPCR R-HSA-372790 6.950813e-01 0.158 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 6.978748e-01 0.156 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 6.978748e-01 0.156 0 0
Opioid Signalling R-HSA-111885 6.978748e-01 0.156 0 0
Nucleotide Excision Repair R-HSA-5696398 7.041214e-01 0.152 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 7.041214e-01 0.152 0 0
Platelet homeostasis R-HSA-418346 7.071963e-01 0.150 0 0
SARS-CoV-1-host interactions R-HSA-9692914 7.071963e-01 0.150 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 7.132512e-01 0.147 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 7.132512e-01 0.147 0 0
Antigen processing-Cross presentation R-HSA-1236975 7.132512e-01 0.147 0 0
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation R-HSA-975138 7.132512e-01 0.147 0 0
MyD88 dependent cascade initiated on endosome R-HSA-975155 7.162318e-01 0.145 0 0
DNA Replication Pre-Initiation R-HSA-69002 7.162318e-01 0.145 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 7.191817e-01 0.143 0 0
MyD88-independent TLR4 cascade R-HSA-166166 7.191817e-01 0.143 0 0
GPCR downstream signalling R-HSA-388396 7.221121e-01 0.141 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 7.249902e-01 0.140 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 7.249902e-01 0.140 0 0
Inositol phosphate metabolism R-HSA-1483249 7.249902e-01 0.140 0 0
Toll Like Receptor 7/8 (TLR7/8) Cascade R-HSA-168181 7.278495e-01 0.138 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 7.278495e-01 0.138 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 7.301217e-01 0.137 0 0
Toll Like Receptor 9 (TLR9) Cascade R-HSA-168138 7.362513e-01 0.133 0 0
rRNA processing R-HSA-72312 7.376306e-01 0.132 0 0
Cap-dependent Translation Initiation R-HSA-72737 7.417088e-01 0.130 0 0
Eukaryotic Translation Initiation R-HSA-72613 7.417088e-01 0.130 0 0
Peptide hormone metabolism R-HSA-2980736 7.443952e-01 0.128 0 0
Mitochondrial biogenesis R-HSA-1592230 7.443952e-01 0.128 0 0
MyD88:MAL(TIRAP) cascade initiated on plasma membrane R-HSA-166058 7.496852e-01 0.125 0 0
Toll Like Receptor TLR6:TLR2 Cascade R-HSA-168188 7.496852e-01 0.125 0 0
Phase II - Conjugation of compounds R-HSA-156580 7.512899e-01 0.124 0 0
Toll Like Receptor TLR1:TLR2 Cascade R-HSA-168179 7.574167e-01 0.121 0 0
Toll Like Receptor 2 (TLR2) Cascade R-HSA-181438 7.574167e-01 0.121 0 0
Sensory perception of sweet, bitter, and umami (glutamate) taste R-HSA-9717207 7.599408e-01 0.119 0 0
MHC class II antigen presentation R-HSA-2132295 7.599408e-01 0.119 0 0
Disorders of transmembrane transporters R-HSA-5619115 7.661518e-01 0.116 0 0
G1/S Transition R-HSA-69206 7.673573e-01 0.115 0 0
Cell Cycle R-HSA-1640170 7.714340e-01 0.113 0 0
G2/M Checkpoints R-HSA-69481 7.721747e-01 0.112 0 0
Adipogenesis R-HSA-9843745 7.837888e-01 0.106 0 0
Sensory perception of taste R-HSA-9717189 7.837888e-01 0.106 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 7.860400e-01 0.105 0 0
Degradation of the extracellular matrix R-HSA-1474228 7.860400e-01 0.105 0 0
Infectious disease R-HSA-5663205 7.899836e-01 0.102 0 0
M Phase R-HSA-68886 7.907053e-01 0.102 0 0
Unfolded Protein Response (UPR) R-HSA-381119 8.032306e-01 0.095 0 0
Macroautophagy R-HSA-1632852 8.073092e-01 0.093 0 0
SLC-mediated transmembrane transport R-HSA-425407 8.107568e-01 0.091 0 0
Biosynthesis of specialized proresolving mediators (SPMs) R-HSA-9018678 8.132700e-01 0.090 0 0
FCERI mediated NF-kB activation R-HSA-2871837 8.152160e-01 0.089 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 8.228002e-01 0.085 0 0
Gastrulation R-HSA-9758941 8.246474e-01 0.084 0 0
Arachidonate metabolism R-HSA-2142753 8.300749e-01 0.081 0 0
Protein localization R-HSA-9609507 8.318467e-01 0.080 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 8.353354e-01 0.078 0 0
PPARA activates gene expression R-HSA-1989781 8.353354e-01 0.078 0 0
Autophagy R-HSA-9612973 8.370527e-01 0.077 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 8.387522e-01 0.076 0 0
Cellular response to starvation R-HSA-9711097 8.404340e-01 0.075 0 0
Regulation of TP53 Activity R-HSA-5633007 8.437456e-01 0.074 0 0
Selenoamino acid metabolism R-HSA-2408522 8.501652e-01 0.070 0 0
SLC transporter disorders R-HSA-5619102 8.548072e-01 0.068 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 8.622283e-01 0.064 0 0
Ub-specific processing proteases R-HSA-5689880 8.650900e-01 0.063 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 8.678927e-01 0.062 0 0
Influenza Infection R-HSA-168255 8.733255e-01 0.059 0 0
Cellular Senescence R-HSA-2559583 8.746487e-01 0.058 0 0
Developmental Biology R-HSA-1266738 8.796128e-01 0.056 1 0
Extracellular matrix organization R-HSA-1474244 8.809624e-01 0.055 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 8.824882e-01 0.054 0 0
Toll-like Receptor Cascades R-HSA-168898 8.883270e-01 0.051 0 0
Glycosaminoglycan metabolism R-HSA-1630316 8.906495e-01 0.050 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 8.984067e-01 0.047 0 0
Glycerophospholipid biosynthesis R-HSA-1483206 9.015613e-01 0.045 0 0
RNA Polymerase II Transcription R-HSA-73857 9.126269e-01 0.040 0 0
Membrane Trafficking R-HSA-199991 9.193861e-01 0.037 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 9.235325e-01 0.035 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.266873e-01 0.033 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.307903e-01 0.031 0 0
ESR-mediated signaling R-HSA-8939211 9.319000e-01 0.031 0 0
Fatty acid metabolism R-HSA-8978868 9.381569e-01 0.028 0 0
Generic Transcription Pathway R-HSA-212436 9.420753e-01 0.026 0 0
Deubiquitination R-HSA-5688426 9.436733e-01 0.025 0 0
Asparagine N-linked glycosylation R-HSA-446203 9.457370e-01 0.024 0 0
Diseases of metabolism R-HSA-5668914 9.480620e-01 0.023 0 0
GPCR ligand binding R-HSA-500792 9.540239e-01 0.020 0 0
Gene expression (Transcription) R-HSA-74160 9.594777e-01 0.018 0 0
Neuronal System R-HSA-112316 9.638649e-01 0.016 0 0
Organelle biogenesis and maintenance R-HSA-1852241 9.716693e-01 0.012 0 0
Epigenetic regulation of gene expression R-HSA-212165 9.725556e-01 0.012 0 0
Transmission across Chemical Synapses R-HSA-112315 9.725556e-01 0.012 0 0
Metabolism of steroids R-HSA-8957322 9.728449e-01 0.012 0 0
Vesicle-mediated transport R-HSA-5653656 9.746379e-01 0.011 0 0
Biological oxidations R-HSA-211859 9.779963e-01 0.010 0 0
Transport of small molecules R-HSA-382551 9.802493e-01 0.009 0 0
DNA Repair R-HSA-73894 9.814655e-01 0.008 0 0
Signaling by Nuclear Receptors R-HSA-9006931 9.820469e-01 0.008 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.822366e-01 0.008 0 0
Metabolism of proteins R-HSA-392499 9.862428e-01 0.006 0 0
Bacterial Infection Pathways R-HSA-9824439 9.866696e-01 0.006 0 0
Metabolism of lipids R-HSA-556833 9.904874e-01 0.004 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.908593e-01 0.004 0 0
Metabolism R-HSA-1430728 9.950240e-01 0.002 0 0
Post-translational protein modification R-HSA-597592 9.971238e-01 0.001 0 0
Sensory Perception R-HSA-9709957 9.999809e-01 0.000 0 0
Semaphorin interactions R-HSA-373755 1.000000e+00 0.000 1 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 1.000000e+00 0.000 1 1
Sema4D in semaphorin signaling R-HSA-400685 1.000000e+00 0.000 1 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.000000e+00 0.000 1 1
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways
Motif of predicted substrate sequence
Reactome pathways of predicted substrates
Download
name reactome_id p -log10p ref_path ref_path_lowest
HSF1 activation R-HSA-3371511 1.110223e-16 15.955 0 0
Attenuation phase R-HSA-3371568 1.110223e-16 15.955 0 0
Cellular response to heat stress R-HSA-3371556 1.110223e-16 15.955 0 0
HSF1-dependent transactivation R-HSA-3371571 1.110223e-16 15.955 0 0
Regulation of HSF1-mediated heat shock response R-HSA-3371453 1.110223e-16 15.955 0 0
Cellular responses to stimuli R-HSA-8953897 1.110223e-16 15.955 0 0
Cellular responses to stress R-HSA-2262752 1.110223e-16 15.955 0 0
G2/M DNA damage checkpoint R-HSA-69473 1.776357e-15 14.750 0 0
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand R-HSA-3371497 6.772360e-15 14.169 0 0
Translocation of SLC2A4 (GLUT4) to the plasma membrane R-HSA-1445148 1.976197e-14 13.704 0 0
M Phase R-HSA-68886 1.278977e-13 12.893 0 0
Axon guidance R-HSA-422475 2.088330e-13 12.680 1 0
DNA Damage/Telomere Stress Induced Senescence R-HSA-2559586 3.742562e-13 12.427 0 0
Cell Cycle R-HSA-1640170 5.825340e-13 12.235 0 0
Nervous system development R-HSA-9675108 1.483369e-12 11.829 1 0
Cell Cycle, Mitotic R-HSA-69278 2.775224e-12 11.557 0 0
G2/M Checkpoints R-HSA-69481 2.736700e-12 11.563 0 0
Viral Infection Pathways R-HSA-9824446 7.332801e-12 11.135 0 0
PKR-mediated signaling R-HSA-9833482 1.093947e-11 10.961 0 0
Replacement of protamines by nucleosomes in the male pronucleus R-HSA-9821993 1.365474e-11 10.865 0 0
Developmental Biology R-HSA-1266738 2.052036e-11 10.688 1 0
Packaging Of Telomere Ends R-HSA-171306 3.716183e-11 10.430 0 0
RNA Polymerase I Promoter Opening R-HSA-73728 3.716183e-11 10.430 0 0
Recruitment of NuMA to mitotic centrosomes R-HSA-380320 4.502876e-11 10.347 0 0
Interleukin-12 signaling R-HSA-9020591 6.226930e-11 10.206 0 0
DNA methylation R-HSA-5334118 6.878953e-11 10.162 0 0
Mitotic Prophase R-HSA-68875 7.338874e-11 10.134 0 0
Antiviral mechanism by IFN-stimulated genes R-HSA-1169410 7.850920e-11 10.105 0 0
HCMV Early Events R-HSA-9609690 9.565071e-11 10.019 0 0
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation R-HSA-8950505 1.092202e-10 9.962 0 0
Meiotic synapsis R-HSA-1221632 1.439472e-10 9.842 0 0
Recognition and association of DNA glycosylase with site containing an affected purine R-HSA-110330 1.621410e-10 9.790 0 0
Assembly of the ORC complex at the origin of replication R-HSA-68616 2.123983e-10 9.673 0 0
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex R-HSA-9843970 3.567785e-10 9.448 0 0
Recognition and association of DNA glycosylase with site containing an affected pyrimidine R-HSA-110328 3.567785e-10 9.448 0 0
Post NMDA receptor activation events R-HSA-438064 3.814112e-10 9.419 0 0
Interleukin-12 family signaling R-HSA-447115 3.814112e-10 9.419 0 0
Condensation of Prophase Chromosomes R-HSA-2299718 4.642002e-10 9.333 0 0
PRC2 methylates histones and DNA R-HSA-212300 5.838036e-10 9.234 0 0
SIRT1 negatively regulates rRNA expression R-HSA-427359 7.400526e-10 9.131 0 0
Cleavage of the damaged purine R-HSA-110331 7.400526e-10 9.131 0 0
EPH-Ephrin signaling R-HSA-2682334 8.609020e-10 9.065 1 0
Depurination R-HSA-73927 9.328045e-10 9.030 0 0
HCMV Infection R-HSA-9609646 1.168849e-09 8.932 0 0
Post-chaperonin tubulin folding pathway R-HSA-389977 1.175324e-09 8.930 0 0
Meiotic recombination R-HSA-912446 1.241457e-09 8.906 0 0
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex R-HSA-75035 1.262949e-09 8.899 0 0
Regulation of PD-L1(CD274) transcription R-HSA-9909649 1.444027e-09 8.840 0 0
Inhibition of DNA recombination at telomere R-HSA-9670095 1.458379e-09 8.836 0 0
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression R-HSA-427389 1.458379e-09 8.836 0 0
B-WICH complex positively regulates rRNA expression R-HSA-5250924 1.794564e-09 8.746 0 0
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 R-HSA-5625886 1.809751e-09 8.742 0 0
Chromatin modifications during the maternal to zygotic transition (MZT) R-HSA-9821002 1.809751e-09 8.742 0 0
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding R-HSA-389958 2.121609e-09 8.673 0 0
Meiosis R-HSA-1500620 2.359496e-09 8.627 0 0
Cleavage of the damaged pyrimidine R-HSA-110329 2.747761e-09 8.561 0 0
Depyrimidination R-HSA-73928 2.747761e-09 8.561 0 0
Activation of NMDA receptors and postsynaptic events R-HSA-442755 3.359597e-09 8.474 0 0
Defective pyroptosis R-HSA-9710421 3.363206e-09 8.473 0 0
Regulation of CDH1 Expression and Function R-HSA-9764265 3.206960e-09 8.494 0 0
Regulation of Expression and Function of Type I Classical Cadherins R-HSA-9764274 3.206960e-09 8.494 0 0
Transcriptional regulation by small RNAs R-HSA-5578749 3.618326e-09 8.441 0 0
Diseases of programmed cell death R-HSA-9645723 3.993247e-09 8.399 0 0
Deposition of new CENPA-containing nucleosomes at the centromere R-HSA-606279 4.975796e-09 8.303 0 0
Nucleosome assembly R-HSA-774815 4.975796e-09 8.303 0 0
Formation of tubulin folding intermediates by CCT/TriC R-HSA-389960 5.610840e-09 8.251 0 0
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) R-HSA-9845323 5.917599e-09 8.228 0 0
Negative Regulation of CDH1 Gene Transcription R-HSA-9764725 5.917599e-09 8.228 0 0
Cell junction organization R-HSA-446728 7.247087e-09 8.140 0 0
The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8852276 8.119228e-09 8.090 0 0
Transcriptional regulation of granulopoiesis R-HSA-9616222 8.119228e-09 8.090 0 0
Nonhomologous End-Joining (NHEJ) R-HSA-5693571 8.698003e-09 8.061 0 0
G2/M Transition R-HSA-69275 9.054766e-09 8.043 0 0
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane R-HSA-190840 9.198287e-09 8.036 0 0
Infectious disease R-HSA-5663205 9.965486e-09 8.002 0 0
Cell Cycle Checkpoints R-HSA-69620 1.002751e-08 7.999 0 0
Mitotic G2-G2/M phases R-HSA-453274 1.054805e-08 7.977 0 0
Nuclear Envelope (NE) Reassembly R-HSA-2995410 1.100679e-08 7.958 0 0
Transport of connexons to the plasma membrane R-HSA-190872 1.292580e-08 7.889 0 0
Senescence-Associated Secretory Phenotype (SASP) R-HSA-2559582 1.428247e-08 7.845 0 0
Cell-Cell communication R-HSA-1500931 1.454463e-08 7.837 0 0
Activation of AMPK downstream of NMDARs R-HSA-9619483 1.626491e-08 7.789 0 0
RNA Polymerase I Promoter Escape R-HSA-73772 1.744694e-08 7.758 0 0
Adherens junctions interactions R-HSA-418990 1.819674e-08 7.740 0 0
Regulation of Homotypic Cell-Cell Adhesion R-HSA-9759476 1.908940e-08 7.719 0 0
Base-Excision Repair, AP Site Formation R-HSA-73929 2.425040e-08 7.615 0 0
Cytokine Signaling in Immune system R-HSA-1280215 2.540963e-08 7.595 0 0
Regulation of CDH1 Gene Transcription R-HSA-9764560 2.622326e-08 7.581 0 0
HDACs deacetylate histones R-HSA-3214815 2.846654e-08 7.546 0 0
Positive epigenetic regulation of rRNA expression R-HSA-5250913 3.007667e-08 7.522 0 0
Programmed Cell Death R-HSA-5357801 3.862206e-08 7.413 0 0
SARS-CoV-1-host interactions R-HSA-9692914 4.449976e-08 7.352 0 0
Formation of the beta-catenin:TCF transactivating complex R-HSA-201722 4.530116e-08 7.344 0 0
Gap junction trafficking R-HSA-190828 5.044426e-08 7.297 0 0
Gene Silencing by RNA R-HSA-211000 4.929329e-08 7.307 0 0
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks R-HSA-5693565 5.261736e-08 7.279 0 0
Activation of BAD and translocation to mitochondria R-HSA-111447 7.220595e-08 7.141 0 0
SARS-CoV-2 targets host intracellular signalling and regulatory pathways R-HSA-9755779 7.220595e-08 7.141 0 0
SARS-CoV-1 targets host intracellular signalling and regulatory pathways R-HSA-9735871 7.220595e-08 7.141 0 0
Recycling pathway of L1 R-HSA-437239 8.434276e-08 7.074 0 0
Signal Transduction R-HSA-162582 9.638426e-08 7.016 1 0
Signaling by ERBB2 TMD/JMD mutants R-HSA-9665686 9.722933e-08 7.012 0 0
Processing of DNA double-strand break ends R-HSA-5693607 1.073838e-07 6.969 0 0
Gap junction trafficking and regulation R-HSA-157858 1.168426e-07 6.932 0 0
L1CAM interactions R-HSA-373760 1.427844e-07 6.845 0 0
Cell-cell junction organization R-HSA-421270 1.444793e-07 6.840 0 0
DNA Double Strand Break Response R-HSA-5693606 1.604867e-07 6.795 0 0
Estrogen-dependent gene expression R-HSA-9018519 1.678199e-07 6.775 0 0
Cellular Senescence R-HSA-2559583 1.731656e-07 6.762 0 0
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-8936459 1.827676e-07 6.738 0 0
EPHA-mediated growth cone collapse R-HSA-3928663 1.990187e-07 6.701 0 0
Regulation of endogenous retroelements by KRAB-ZFP proteins R-HSA-9843940 2.357009e-07 6.628 0 0
Apoptosis R-HSA-109581 2.381241e-07 6.623 0 0
Aggrephagy R-HSA-9646399 2.450055e-07 6.611 0 0
NoRC negatively regulates rRNA expression R-HSA-427413 2.669345e-07 6.574 0 0
Signaling by ERBB2 KD Mutants R-HSA-9664565 3.090073e-07 6.510 0 0
Developmental Lineage of Mammary Gland Myoepithelial Cells R-HSA-9927432 3.090073e-07 6.510 0 0
Assembly and cell surface presentation of NMDA receptors R-HSA-9609736 3.456114e-07 6.461 0 0
Cilium Assembly R-HSA-5617833 3.399575e-07 6.469 0 0
Signaling by ERBB2 in Cancer R-HSA-1227990 3.812123e-07 6.419 0 0
SHC1 events in ERBB2 signaling R-HSA-1250196 3.812123e-07 6.419 0 0
Downregulation of ERBB2 signaling R-HSA-8863795 3.812123e-07 6.419 0 0
Mitotic Prometaphase R-HSA-68877 4.129929e-07 6.384 0 0
Eukaryotic Translation Elongation R-HSA-156842 4.493038e-07 6.347 0 0
RNA Polymerase I Promoter Clearance R-HSA-73854 4.847497e-07 6.314 0 0
Reproduction R-HSA-1474165 5.628850e-07 6.250 0 0
Signaling by ERBB2 R-HSA-1227986 5.745946e-07 6.241 0 0
RNA Polymerase I Transcription R-HSA-73864 6.085657e-07 6.216 0 0
Sealing of the nuclear envelope (NE) by ESCRT-III R-HSA-9668328 6.906178e-07 6.161 0 0
Negative epigenetic regulation of rRNA expression R-HSA-5250941 7.594779e-07 6.119 0 0
TP53 Regulates Metabolic Genes R-HSA-5628897 7.631963e-07 6.117 0 0
Apoptotic execution phase R-HSA-75153 7.668352e-07 6.115 0 0
Telomere Maintenance R-HSA-157579 8.117201e-07 6.091 0 0
EPH-ephrin mediated repulsion of cells R-HSA-3928665 8.906189e-07 6.050 0 0
Loss of proteins required for interphase microtubule organization from the centrosome R-HSA-380284 8.443640e-07 6.073 0 0
Loss of Nlp from mitotic centrosomes R-HSA-380259 8.443640e-07 6.073 0 0
HATs acetylate histones R-HSA-3214847 9.803126e-07 6.009 0 0
Amyloid fiber formation R-HSA-977225 8.466176e-07 6.072 0 0
Gap junction assembly R-HSA-190861 9.991862e-07 6.000 0 0
ERBB2 Activates PTK6 Signaling R-HSA-8847993 1.120441e-06 5.951 0 0
Regulation of PLK1 Activity at G2/M Transition R-HSA-2565942 1.163164e-06 5.934 0 0
RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939236 1.163164e-06 5.934 0 0
Prefoldin mediated transfer of substrate to CCT/TriC R-HSA-389957 1.196971e-06 5.922 0 0
AURKA Activation by TPX2 R-HSA-8854518 1.218831e-06 5.914 0 0
Regulation of endogenous retroelements R-HSA-9842860 1.291498e-06 5.889 0 0
Oxidative Stress Induced Senescence R-HSA-2559580 1.291498e-06 5.889 0 0
Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112314 1.391616e-06 5.856 0 0
ERBB2 Regulates Cell Motility R-HSA-6785631 1.526824e-06 5.816 0 0
Maternal to zygotic transition (MZT) R-HSA-9816359 1.601722e-06 5.795 0 0
Selective autophagy R-HSA-9663891 1.925029e-06 5.716 0 0
Immune System R-HSA-168256 2.055849e-06 5.687 1 0
Base Excision Repair R-HSA-73884 2.335225e-06 5.632 0 0
Disease R-HSA-1643685 2.533486e-06 5.596 0 0
Regulation of PD-L1(CD274) expression R-HSA-9909648 2.560811e-06 5.592 0 0
Pre-NOTCH Transcription and Translation R-HSA-1912408 2.567669e-06 5.590 0 0
DNA Replication Pre-Initiation R-HSA-69002 2.587792e-06 5.587 0 0
COPI-independent Golgi-to-ER retrograde traffic R-HSA-6811436 2.671034e-06 5.573 0 0
Recruitment of mitotic centrosome proteins and complexes R-HSA-380270 2.698278e-06 5.569 0 0
Centrosome maturation R-HSA-380287 3.337981e-06 5.477 0 0
Co-inhibition by PD-1 R-HSA-389948 2.956128e-06 5.529 0 0
Protein folding R-HSA-391251 3.094123e-06 5.509 0 0
Non-integrin membrane-ECM interactions R-HSA-3000171 3.337981e-06 5.477 0 0
Assembly of the pre-replicative complex R-HSA-68867 3.391129e-06 5.470 0 0
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) R-HSA-5693567 3.888764e-06 5.410 0 0
Depolymerization of the Nuclear Lamina R-HSA-4419969 4.525906e-06 5.344 0 0
Activation of BH3-only proteins R-HSA-114452 4.889865e-06 5.311 0 0
Interferon Signaling R-HSA-913531 5.033617e-06 5.298 0 0
Homology Directed Repair R-HSA-5693538 6.184430e-06 5.209 0 0
Regulation of localization of FOXO transcription factors R-HSA-9614399 6.455277e-06 5.190 0 0
Chromosome Maintenance R-HSA-73886 7.725878e-06 5.112 0 0
Carboxyterminal post-translational modifications of tubulin R-HSA-8955332 8.452442e-06 5.073 0 0
Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5617472 1.022857e-05 4.990 0 0
Activation of HOX genes during differentiation R-HSA-5619507 1.022857e-05 4.990 0 0
Chaperonin-mediated protein folding R-HSA-390466 1.168199e-05 4.932 0 0
Regulation of T cell activation by CD28 family R-HSA-388841 1.325035e-05 4.878 0 0
Factors involved in megakaryocyte development and platelet production R-HSA-983231 1.409749e-05 4.851 0 0
SARS-CoV-1 Infection R-HSA-9678108 1.409749e-05 4.851 0 0
Anchoring of the basal body to the plasma membrane R-HSA-5620912 1.516666e-05 4.819 0 0
E3 ubiquitin ligases ubiquitinate target proteins R-HSA-8866654 1.570451e-05 4.804 0 0
Cargo trafficking to the periciliary membrane R-HSA-5620920 1.598828e-05 4.796 0 0
Smooth Muscle Contraction R-HSA-445355 1.765238e-05 4.753 0 0
Autophagy R-HSA-9612973 2.000193e-05 4.699 0 0
Pre-NOTCH Expression and Processing R-HSA-1912422 2.021509e-05 4.694 0 0
ESR-mediated signaling R-HSA-8939211 2.093474e-05 4.679 0 0
COPI-mediated anterograde transport R-HSA-6807878 2.913162e-05 4.536 0 0
Mitotic Anaphase R-HSA-68882 3.000535e-05 4.523 0 0
Mitotic Metaphase and Anaphase R-HSA-2555396 3.146845e-05 4.502 0 0
Kinesins R-HSA-983189 3.781984e-05 4.422 0 0
Resolution of Sister Chromatid Cohesion R-HSA-2500257 4.031758e-05 4.395 0 0
GRB2 events in ERBB2 signaling R-HSA-1963640 4.427336e-05 4.354 0 0
Semaphorin interactions R-HSA-373755 5.102670e-05 4.292 1 0
MAPK family signaling cascades R-HSA-5683057 4.396913e-05 4.357 0 0
SARS-CoV-2-host interactions R-HSA-9705683 5.222651e-05 4.282 0 0
Organelle biogenesis and maintenance R-HSA-1852241 5.272278e-05 4.278 0 0
Ub-specific processing proteases R-HSA-5689880 5.417858e-05 4.266 0 0
PI3K events in ERBB2 signaling R-HSA-1963642 5.506188e-05 4.259 0 0
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis R-HSA-9841922 5.563323e-05 4.255 0 0
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes R-HSA-9851695 5.563323e-05 4.255 0 0
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes R-HSA-9818564 5.563323e-05 4.255 0 0
Drug resistance in ERBB2 KD mutants R-HSA-9665230 5.727015e-05 4.242 0 0
Drug-mediated inhibition of ERBB2 signaling R-HSA-9652282 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to lapatinib R-HSA-9665251 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to neratinib R-HSA-9665246 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to afatinib R-HSA-9665249 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to sapitinib R-HSA-9665244 5.727015e-05 4.242 0 0
Drug resistance in ERBB2 TMD/JMD mutants R-HSA-9665737 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to AEE788 R-HSA-9665250 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to trastuzumab R-HSA-9665233 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to tesevatinib R-HSA-9665245 5.727015e-05 4.242 0 0
Resistance of ERBB2 KD mutants to osimertinib R-HSA-9665247 5.727015e-05 4.242 0 0
Transmission across Chemical Synapses R-HSA-112315 5.888236e-05 4.230 0 0
Formation of the dystrophin-glycoprotein complex (DGC) R-HSA-9913351 6.368420e-05 4.196 0 0
DNA Double-Strand Break Repair R-HSA-5693532 7.492240e-05 4.125 0 0
DNA Replication R-HSA-69306 7.492240e-05 4.125 0 0
EML4 and NUDC in mitotic spindle formation R-HSA-9648025 8.016443e-05 4.096 0 0
Membrane Trafficking R-HSA-199991 8.483073e-05 4.071 0 0
Signaling by NOTCH R-HSA-157118 8.777219e-05 4.057 0 0
Signaling by Receptor Tyrosine Kinases R-HSA-9006934 8.937144e-05 4.049 0 0
TCF dependent signaling in response to WNT R-HSA-201681 8.957721e-05 4.048 0 0
HCMV Late Events R-HSA-9610379 9.287610e-05 4.032 0 0
Adaptive Immune System R-HSA-1280218 9.731803e-05 4.012 0 0
Apoptosis induced DNA fragmentation R-HSA-140342 9.932173e-05 4.003 0 0
Developmental Lineages of the Mammary Gland R-HSA-9924644 1.155481e-04 3.937 0 0
Signaling by Interleukins R-HSA-449147 1.201983e-04 3.920 0 0
VEGFA-VEGFR2 Pathway R-HSA-4420097 1.343242e-04 3.872 0 0
Cap-dependent Translation Initiation R-HSA-72737 1.428765e-04 3.845 0 0
Eukaryotic Translation Initiation R-HSA-72613 1.428765e-04 3.845 0 0
Protein ubiquitination R-HSA-8852135 1.481815e-04 3.829 0 0
Macroautophagy R-HSA-1632852 1.589511e-04 3.799 0 0
Deubiquitination R-HSA-5688426 1.606438e-04 3.794 0 0
Transcriptional regulation by RUNX1 R-HSA-8878171 1.725239e-04 3.763 0 0
Intrinsic Pathway for Apoptosis R-HSA-109606 1.797543e-04 3.745 0 0
Nuclear Envelope Breakdown R-HSA-2980766 1.973659e-04 3.705 0 0
Regulation of CDH1 Function R-HSA-9764561 1.973659e-04 3.705 0 0
Developmental Cell Lineages R-HSA-9734767 2.176860e-04 3.662 0 0
ER to Golgi Anterograde Transport R-HSA-199977 2.296246e-04 3.639 0 0
Signaling by WNT R-HSA-195721 2.406582e-04 3.619 0 0
Formation of Senescence-Associated Heterochromatin Foci (SAHF) R-HSA-2559584 2.746369e-04 3.561 0 0
Epigenetic regulation by WDR5-containing histone modifying complexes R-HSA-9917777 3.252394e-04 3.488 0 0
Signaling by VEGF R-HSA-194138 2.567756e-04 3.590 0 0
SARS-CoV Infections R-HSA-9679506 3.321647e-04 3.479 0 0
Signaling by PTK6 R-HSA-8848021 3.345610e-04 3.476 0 0
Signaling by Non-Receptor Tyrosine Kinases R-HSA-9006927 3.345610e-04 3.476 0 0
GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72706 3.660598e-04 3.436 0 0
L13a-mediated translational silencing of Ceruloplasmin expression R-HSA-156827 3.660598e-04 3.436 0 0
Developmental Cell Lineages of the Integumentary System R-HSA-9734779 3.660598e-04 3.436 0 0
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors R-HSA-8864260 3.928968e-04 3.406 0 0
Peptide chain elongation R-HSA-156902 4.166297e-04 3.380 0 0
Sema3A PAK dependent Axon repulsion R-HSA-399954 4.167203e-04 3.380 1 1
Protein methylation R-HSA-8876725 4.167203e-04 3.380 0 0
Cell-extracellular matrix interactions R-HSA-446353 4.167203e-04 3.380 0 0
Vesicle-mediated transport R-HSA-5653656 5.002480e-04 3.301 0 0
Intraflagellar transport R-HSA-5620924 5.777138e-04 3.238 0 0
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-8866910 6.047677e-04 3.218 0 0
Regulation of mRNA stability by proteins that bind AU-rich elements R-HSA-450531 6.738886e-04 3.171 0 0
MAPK1/MAPK3 signaling R-HSA-5684996 6.766750e-04 3.170 0 0
Diseases of signal transduction by growth factor receptors and second messengers R-HSA-5663202 7.627795e-04 3.118 0 0
COPI-dependent Golgi-to-ER retrograde traffic R-HSA-6811434 7.846328e-04 3.105 0 0
Uptake and function of diphtheria toxin R-HSA-5336415 8.267312e-04 3.083 0 0
Chaperone Mediated Autophagy R-HSA-9613829 8.462878e-04 3.072 0 0
Signaling by ERBB2 ECD mutants R-HSA-9665348 8.462878e-04 3.072 0 0
MHC class II antigen presentation R-HSA-2132295 9.294273e-04 3.032 0 0
Rap1 signalling R-HSA-392517 9.894747e-04 3.005 0 0
Glycolysis R-HSA-70171 9.904352e-04 3.004 0 0
Hedgehog 'off' state R-HSA-5610787 9.904352e-04 3.004 0 0
Influenza Infection R-HSA-168255 1.021720e-03 2.991 0 0
Downregulation of ERBB4 signaling R-HSA-1253288 1.085998e-03 2.964 0 0
ROBO receptors bind AKAP5 R-HSA-9010642 1.085998e-03 2.964 0 0
Muscle contraction R-HSA-397014 1.123589e-03 2.949 0 0
SARS-CoV-2 Infection R-HSA-9694516 1.162046e-03 2.935 0 0
Manipulation of host energy metabolism R-HSA-9636667 1.384458e-03 2.859 0 0
HuR (ELAVL1) binds and stabilizes mRNA R-HSA-450520 1.391510e-03 2.857 0 0
Hemostasis R-HSA-109582 1.436414e-03 2.843 0 0
Neuronal System R-HSA-112316 1.480300e-03 2.830 0 0
Initiation of Nuclear Envelope (NE) Reformation R-HSA-2995383 1.520181e-03 2.818 0 0
RAF/MAP kinase cascade R-HSA-5673001 1.560346e-03 2.807 0 0
Golgi-to-ER retrograde transport R-HSA-8856688 1.574057e-03 2.803 0 0
Response to elevated platelet cytosolic Ca2+ R-HSA-76005 1.647047e-03 2.783 0 0
Metabolism of RNA R-HSA-8953854 1.690588e-03 2.772 0 0
Signaling by Nuclear Receptors R-HSA-9006931 1.690963e-03 2.772 0 0
Developmental Lineage of Mammary Stem Cells R-HSA-9938206 1.733962e-03 2.761 0 0
Separation of Sister Chromatids R-HSA-2467813 1.851479e-03 2.732 0 0
Syndecan interactions R-HSA-3000170 1.967753e-03 2.706 0 0
Respiratory Syncytial Virus Infection Pathway R-HSA-9820952 2.053800e-03 2.687 0 0
Signaling by Hedgehog R-HSA-5358351 2.144020e-03 2.669 0 0
Chromatin modifying enzymes R-HSA-3247509 2.366439e-03 2.626 0 0
Transport to the Golgi and subsequent modification R-HSA-948021 2.396912e-03 2.620 0 0
Signaling by ROBO receptors R-HSA-376176 2.480306e-03 2.605 0 0
Long-term potentiation R-HSA-9620244 2.499069e-03 2.602 0 0
EPHB-mediated forward signaling R-HSA-3928662 2.634587e-03 2.579 1 1
Glucose metabolism R-HSA-70326 2.754113e-03 2.560 0 0
Mitochondrial unfolded protein response (UPRmt) R-HSA-9841251 3.121438e-03 2.506 0 0
Constitutive Signaling by Overexpressed ERBB2 R-HSA-9634285 3.129821e-03 2.504 0 0
Formation of a pool of free 40S subunits R-HSA-72689 3.275423e-03 2.485 0 0
Translation R-HSA-72766 3.431053e-03 2.465 0 0
Gluconeogenesis R-HSA-70263 3.603696e-03 2.443 0 0
Chromatin organization R-HSA-4839726 3.732242e-03 2.428 0 0
Signaling by ERBB4 R-HSA-1236394 3.885199e-03 2.411 0 0
Negative regulation of the PI3K/AKT network R-HSA-199418 5.024644e-03 2.299 0 0
Apoptotic cleavage of cellular proteins R-HSA-111465 5.121734e-03 2.291 0 0
PLCG1 events in ERBB2 signaling R-HSA-1251932 5.345807e-03 2.272 0 0
GRB7 events in ERBB2 signaling R-HSA-1306955 5.345807e-03 2.272 0 0
MTF1 activates gene expression R-HSA-5660489 5.345807e-03 2.272 0 0
Metabolism of proteins R-HSA-392499 5.493677e-03 2.260 0 0
Translation initiation complex formation R-HSA-72649 5.501995e-03 2.259 0 0
Intracellular signaling by second messengers R-HSA-9006925 6.246934e-03 2.204 0 0
Ribosomal scanning and start codon recognition R-HSA-72702 6.267138e-03 2.203 0 0
SHC1 events in ERBB4 signaling R-HSA-1250347 6.629076e-03 2.179 0 0
Constitutive Signaling by EGFRvIII R-HSA-5637810 7.523253e-03 2.124 0 0
Signaling by EGFRvIII in Cancer R-HSA-5637812 7.523253e-03 2.124 0 0
Ephrin signaling R-HSA-3928664 8.485331e-03 2.071 0 0
SARS-CoV-1 modulates host translation machinery R-HSA-9735869 6.659677e-03 2.177 0 0
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA R-HSA-9954714 9.827785e-03 2.008 0 0
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72662 7.104087e-03 2.148 0 0
Oncogenic MAPK signaling R-HSA-6802957 7.040861e-03 2.152 0 0
Signaling by high-kinase activity BRAF mutants R-HSA-6802948 8.476130e-03 2.072 0 0
PKA-mediated phosphorylation of key metabolic factors R-HSA-163358 9.283472e-03 2.032 0 0
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest R-HSA-6804114 6.629076e-03 2.179 0 0
Calmodulin induced events R-HSA-111933 7.838516e-03 2.106 0 0
CaM pathway R-HSA-111997 7.838516e-03 2.106 0 0
Respiratory syncytial virus (RSV) genome replication, transcription and translation R-HSA-9820965 9.851072e-03 2.007 0 0
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-975956 1.028179e-02 1.988 0 0
PI3K/AKT Signaling in Cancer R-HSA-2219528 1.034050e-02 1.985 0 0
Nuclear signaling by ERBB4 R-HSA-1251985 1.058966e-02 1.975 0 0
Sema4D induced cell migration and growth-cone collapse R-HSA-416572 1.061735e-02 1.974 1 1
Signaling by BRAF and RAF1 fusions R-HSA-6802952 1.064543e-02 1.973 0 0
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation R-HSA-8869496 1.161279e-02 1.935 0 0
Nef and signal transduction R-HSA-164944 1.161279e-02 1.935 0 0
Constitutive Signaling by Aberrant PI3K in Cancer R-HSA-2219530 1.173302e-02 1.931 0 0
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants R-HSA-1236382 1.178907e-02 1.929 0 0
Signaling by Ligand-Responsive EGFR Variants in Cancer R-HSA-5637815 1.178907e-02 1.929 0 0
MAP2K and MAPK activation R-HSA-5674135 1.217204e-02 1.915 0 0
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA R-HSA-9954716 1.224729e-02 1.912 0 0
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling R-HSA-6811558 1.245912e-02 1.905 0 0
Sensory processing of sound by inner hair cells of the cochlea R-HSA-9662360 1.247758e-02 1.904 0 0
Eukaryotic Translation Termination R-HSA-72764 1.277723e-02 1.894 0 0
Developmental Lineage of Mammary Gland Luminal Epithelial Cells R-HSA-9927418 1.301694e-02 1.885 0 0
Ca-dependent events R-HSA-111996 1.301694e-02 1.885 0 0
rRNA processing in the nucleus and cytosol R-HSA-8868773 1.315560e-02 1.881 0 0
Neutrophil degranulation R-HSA-6798695 1.317597e-02 1.880 0 0
Influenza Viral RNA Transcription and Replication R-HSA-168273 1.355697e-02 1.868 0 0
Disinhibition of SNARE formation R-HSA-114516 1.417034e-02 1.849 0 0
SHOC2 M1731 mutant abolishes MRAS complex function R-HSA-9726840 1.417034e-02 1.849 0 0
CHL1 interactions R-HSA-447041 1.417034e-02 1.849 0 0
Transcriptional and post-translational regulation of MITF-M expression and activity R-HSA-9856649 1.451239e-02 1.838 0 0
Platelet degranulation R-HSA-114608 1.487412e-02 1.828 0 0
Transcriptional Regulation by TP53 R-HSA-3700989 1.516239e-02 1.819 0 0
DAG and IP3 signaling R-HSA-1489509 1.577270e-02 1.802 0 0
Selenocysteine synthesis R-HSA-2408557 1.629834e-02 1.788 0 0
Signaling downstream of RAS mutants R-HSA-9649948 1.676654e-02 1.776 0 0
Paradoxical activation of RAF signaling by kinase inactive BRAF R-HSA-6802955 1.676654e-02 1.776 0 0
Signaling by moderate kinase activity BRAF mutants R-HSA-6802946 1.676654e-02 1.776 0 0
Signaling by RAS mutants R-HSA-6802949 1.676654e-02 1.776 0 0
Formation of annular gap junctions R-HSA-196025 1.694735e-02 1.771 0 0
Signaling by MRAS-complex mutants R-HSA-9660537 1.694735e-02 1.771 0 0
Gain-of-function MRAS complexes activate RAF signaling R-HSA-9726842 1.694735e-02 1.771 0 0
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells R-HSA-8939246 1.694735e-02 1.771 0 0
Plasma lipoprotein assembly R-HSA-8963898 1.719607e-02 1.765 0 0
CD209 (DC-SIGN) signaling R-HSA-5621575 1.719607e-02 1.765 0 0
Neurodegenerative Diseases R-HSA-8863678 1.719607e-02 1.765 0 0
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models R-HSA-8862803 1.719607e-02 1.765 0 0
Viral mRNA Translation R-HSA-192823 1.760742e-02 1.754 0 0
Platelet activation, signaling and aggregation R-HSA-76002 1.801181e-02 1.744 0 0
Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-6811442 1.823007e-02 1.739 0 0
Response of EIF2AK4 (GCN2) to amino acid deficiency R-HSA-9633012 1.828829e-02 1.738 0 0
VEGFR2 mediated cell proliferation R-HSA-5218921 1.873010e-02 1.727 0 0
Sema4D in semaphorin signaling R-HSA-400685 1.873010e-02 1.727 1 0
Gap junction degradation R-HSA-190873 1.993530e-02 1.700 0 0
GP1b-IX-V activation signalling R-HSA-430116 1.993530e-02 1.700 0 0
Respiratory syncytial virus genome replication R-HSA-9834752 1.993530e-02 1.700 0 0
Signaling by EGFR in Cancer R-HSA-1643713 2.033761e-02 1.692 0 0
DNA Repair R-HSA-73894 2.062466e-02 1.686 0 0
Sensory processing of sound R-HSA-9659379 2.099477e-02 1.678 0 0
SRP-dependent cotranslational protein targeting to membrane R-HSA-1799339 2.119193e-02 1.674 0 0
Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-6791226 2.167078e-02 1.664 0 0
Epigenetic regulation of gene expression R-HSA-212165 2.199606e-02 1.658 0 0
Interaction between L1 and Ankyrins R-HSA-445095 2.201873e-02 1.657 0 0
Defective Intrinsic Pathway for Apoptosis R-HSA-9734009 2.201873e-02 1.657 0 0
Folding of actin by CCT/TriC R-HSA-390450 2.312589e-02 1.636 0 0
EGFR Transactivation by Gastrin R-HSA-2179392 2.312589e-02 1.636 0 0
Assembly and release of respiratory syncytial virus (RSV) virions R-HSA-9820962 2.312589e-02 1.636 0 0
Nonsense-Mediated Decay (NMD) R-HSA-927802 2.524092e-02 1.598 0 0
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975957 2.524092e-02 1.598 0 0
Extracellular matrix organization R-HSA-1474244 2.565579e-02 1.591 0 0
MAPK6/MAPK4 signaling R-HSA-5687128 2.693054e-02 1.570 0 0
Clathrin-mediated endocytosis R-HSA-8856828 2.709909e-02 1.567 0 0
Sensory processing of sound by outer hair cells of the cochlea R-HSA-9662361 2.887124e-02 1.540 0 0
Detoxification of Reactive Oxygen Species R-HSA-3299685 2.887124e-02 1.540 0 0
PI3K events in ERBB4 signaling R-HSA-1250342 3.008291e-02 1.522 0 0
TP53 Regulates Transcription of Cell Cycle Genes R-HSA-6791312 3.030462e-02 1.518 0 0
G0 and Early G1 R-HSA-1538133 3.152706e-02 1.501 0 0
Regulation of necroptotic cell death R-HSA-5675482 3.364800e-02 1.473 0 0
Z-decay: degradation of maternal mRNAs by zygotically expressed factors R-HSA-9820865 3.383387e-02 1.471 0 0
Scavenging by Class F Receptors R-HSA-3000484 3.383387e-02 1.471 0 0
Phosphorylation and nuclear translocation of the CRY:PER:kinase complex R-HSA-9931530 3.383387e-02 1.471 0 0
Downregulation of ERBB2:ERBB3 signaling R-HSA-1358803 3.383387e-02 1.471 0 0
Regulation of PAK-2p34 activity by PS-GAP/RHG10 R-HSA-211728 3.513970e-02 1.454 0 0
Inhibition of PKR R-HSA-169131 3.513970e-02 1.454 0 0
Striated Muscle Contraction R-HSA-390522 3.584129e-02 1.446 0 0
PLC beta mediated events R-HSA-112043 3.645296e-02 1.438 0 0
Interleukin-4 and Interleukin-13 signaling R-HSA-6785807 3.773396e-02 1.423 0 0
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) R-HSA-9661069 3.775649e-02 1.423 0 0
CREB1 phosphorylation through the activation of Adenylate Cyclase R-HSA-442720 3.775649e-02 1.423 0 0
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects R-HSA-9659787 3.775649e-02 1.423 0 0
rRNA processing R-HSA-72312 3.930436e-02 1.406 0 0
Mitochondrial protein degradation R-HSA-9837999 4.036860e-02 1.394 0 0
HDL assembly R-HSA-8963896 4.184354e-02 1.378 0 0
Triglyceride catabolism R-HSA-163560 4.285055e-02 1.368 0 0
RET signaling R-HSA-8853659 4.285055e-02 1.368 0 0
STAT3 nuclear events downstream of ALK signaling R-HSA-9701898 4.608802e-02 1.336 0 0
G-protein mediated events R-HSA-112040 4.692755e-02 1.329 0 0
Selenoamino acid metabolism R-HSA-2408522 4.705358e-02 1.327 0 0
RIPK1-mediated regulated necrosis R-HSA-5213460 4.787562e-02 1.320 0 0
FOXO-mediated transcription R-HSA-9614085 4.914611e-02 1.309 0 0
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 R-HSA-1362300 5.048310e-02 1.297 0 0
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism R-HSA-9634600 5.048310e-02 1.297 0 0
WNT5A-dependent internalization of FZD4 R-HSA-5099900 5.048310e-02 1.297 0 0
Developmental Lineage of Pancreatic Ductal Cells R-HSA-9925563 5.075298e-02 1.295 0 0
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9630794 5.224533e-02 1.282 0 0
Signaling by TCF7L2 mutants R-HSA-5339700 5.224533e-02 1.282 0 0
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 R-HSA-9632700 5.224533e-02 1.282 0 0
PTEN Loss of Function in Cancer R-HSA-5674404 5.224533e-02 1.282 0 0
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects R-HSA-9632693 5.224533e-02 1.282 0 0
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects R-HSA-9630750 5.224533e-02 1.282 0 0
Breakdown of the nuclear lamina R-HSA-352238 5.224533e-02 1.282 0 0
Generic Transcription Pathway R-HSA-212436 5.254824e-02 1.279 0 0
Generation of second messenger molecules R-HSA-202433 5.317634e-02 1.274 0 0
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation R-HSA-2892247 5.502214e-02 1.259 0 0
Response to metal ions R-HSA-5660526 5.502214e-02 1.259 0 0
Post-translational protein modification R-HSA-597592 5.554657e-02 1.255 0 0
VEGFR2 mediated vascular permeability R-HSA-5218920 5.592822e-02 1.252 0 0
Stimulation of the cell death response by PAK-2p34 R-HSA-211736 6.904874e-02 1.161 0 0
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes R-HSA-69200 1.017701e-01 0.992 0 0
Regulation of PD-L1(CD274) translation R-HSA-9909620 7.449178e-02 1.128 0 0
FGFR2 alternative splicing R-HSA-6803529 9.030747e-02 1.044 0 0
Deadenylation of mRNA R-HSA-429947 1.013466e-01 0.994 0 0
Translocation of ZAP-70 to Immunological synapse R-HSA-202430 1.013466e-01 0.994 0 0
mRNA Splicing - Major Pathway R-HSA-72163 9.040768e-02 1.044 0 0
Signaling by RAF1 mutants R-HSA-9656223 5.874671e-02 1.231 0 0
Ribosome-associated quality control R-HSA-9948299 6.178926e-02 1.209 0 0
mRNA Splicing R-HSA-72172 1.098591e-01 0.959 0 0
Trafficking of GluR2-containing AMPA receptors R-HSA-416993 6.450653e-02 1.190 0 0
Regulation of actin dynamics for phagocytic cup formation R-HSA-2029482 6.642994e-02 1.178 1 1
PKA-mediated phosphorylation of CREB R-HSA-111931 7.965755e-02 1.099 0 0
Fcgamma receptor (FCGR) dependent phagocytosis R-HSA-2029480 6.049130e-02 1.218 1 0
Gastrin-CREB signalling pathway via PKC and MAPK R-HSA-881907 6.943952e-02 1.158 0 0
Regulation of PTEN mRNA translation R-HSA-8943723 9.578095e-02 1.019 0 0
PIP3 activates AKT signaling R-HSA-1257604 5.914273e-02 1.228 0 0
Localization of the PINCH-ILK-PARVIN complex to focal adhesions R-HSA-446343 6.904874e-02 1.161 0 0
STAT6-mediated induction of chemokines R-HSA-3249367 8.555524e-02 1.068 0 0
MET interacts with TNS proteins R-HSA-8875513 8.555524e-02 1.068 0 0
Drug-mediated inhibition of CDK4/CDK6 activity R-HSA-9754119 1.017701e-01 0.992 0 0
Synaptic adhesion-like molecules R-HSA-8849932 6.450653e-02 1.190 0 0
PKA activation R-HSA-163615 6.450653e-02 1.190 0 0
PKA activation in glucagon signalling R-HSA-164378 6.450653e-02 1.190 0 0
Export of Viral Ribonucleoproteins from Nucleus R-HSA-168274 7.380759e-02 1.132 0 0
GPER1 signaling R-HSA-9634597 8.026633e-02 1.095 0 0
mTORC1-mediated signalling R-HSA-166208 9.030747e-02 1.044 0 0
Diseases of Cellular Senescence R-HSA-9630747 6.904874e-02 1.161 0 0
Diseases of cellular response to stress R-HSA-9675132 6.904874e-02 1.161 0 0
NADE modulates death signalling R-HSA-205025 1.017701e-01 0.992 0 0
Laminin interactions R-HSA-3000157 1.069994e-01 0.971 0 0
Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72695 7.380759e-02 1.132 0 0
Host Interactions of HIV factors R-HSA-162909 1.037370e-01 0.984 0 0
ISG15 antiviral mechanism R-HSA-1169408 6.322096e-02 1.199 0 0
G alpha (z) signalling events R-HSA-418597 1.046757e-01 0.980 0 0
SARS-CoV-2 activates/modulates innate and adaptive immune responses R-HSA-9705671 6.963401e-02 1.157 0 0
Plasma lipoprotein assembly, remodeling, and clearance R-HSA-174824 1.120258e-01 0.951 0 0
Basigin interactions R-HSA-210991 7.965755e-02 1.099 0 0
Developmental Cell Lineages of the Exocrine Pancreas R-HSA-9820448 8.697059e-02 1.061 0 0
Signal transduction by L1 R-HSA-445144 7.449178e-02 1.128 0 0
Cellular response to starvation R-HSA-9711097 9.841136e-02 1.007 0 0
Potential therapeutics for SARS R-HSA-9679191 8.332884e-02 1.079 0 0
NOTCH4 Intracellular Domain Regulates Transcription R-HSA-9013695 7.965755e-02 1.099 0 0
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation R-HSA-9825892 8.493125e-02 1.071 0 0
Regulation of expression of SLITs and ROBOs R-HSA-9010553 8.697059e-02 1.061 0 0
Pyruvate metabolism R-HSA-70268 9.515863e-02 1.022 0 0
Signaling by Hippo R-HSA-2028269 5.969871e-02 1.224 0 0
SARS-CoV-1 activates/modulates innate immune responses R-HSA-9692916 9.388388e-02 1.027 0 0
The role of Nef in HIV-1 replication and disease pathogenesis R-HSA-164952 9.578095e-02 1.019 0 0
MITF-M-regulated melanocyte development R-HSA-9730414 6.033282e-02 1.219 0 0
Uptake and actions of bacterial toxins R-HSA-5339562 9.388388e-02 1.027 0 0
IRS activation R-HSA-74713 1.176984e-01 0.929 0 0
G2 Phase R-HSA-68911 1.176984e-01 0.929 0 0
Loss of phosphorylation of MECP2 at T308 R-HSA-9022535 1.176984e-01 0.929 0 0
IRF3 mediated activation of type 1 IFN R-HSA-1606341 1.176984e-01 0.929 0 0
Nectin/Necl trans heterodimerization R-HSA-420597 1.176984e-01 0.929 0 0
Triglyceride metabolism R-HSA-8979227 1.197786e-01 0.922 0 0
Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide R-HSA-9954709 1.239563e-01 0.907 0 0
DARPP-32 events R-HSA-180024 1.303884e-01 0.885 0 0
Plus-strand DNA synthesis R-HSA-164525 1.333452e-01 0.875 0 0
CDH11 homotypic and heterotypic interactions R-HSA-9833576 1.333452e-01 0.875 0 0
PTK6 Regulates Cell Cycle R-HSA-8849470 1.333452e-01 0.875 0 0
Inhibition of Signaling by Overexpressed EGFR R-HSA-5638303 1.333452e-01 0.875 0 0
Signaling by Overexpressed Wild-Type EGFR in Cancer R-HSA-5638302 1.333452e-01 0.875 0 0
Aryl hydrocarbon receptor signalling R-HSA-8937144 1.333452e-01 0.875 0 0
Phosphorylation of Emi1 R-HSA-176417 1.333452e-01 0.875 0 0
Regulation of CDH19 Expression and Function R-HSA-9764302 1.333452e-01 0.875 0 0
RNA Polymerase II Transcription R-HSA-73857 1.337958e-01 0.874 0 0
Aberrant regulation of mitotic cell cycle due to RB1 defects R-HSA-9687139 1.364077e-01 0.865 0 0
Trafficking of AMPA receptors R-HSA-399719 1.424875e-01 0.846 0 0
Respiratory syncytial virus (RSV) attachment and entry R-HSA-9820960 1.424875e-01 0.846 0 0
Diseases of mitotic cell cycle R-HSA-9675126 1.486236e-01 0.828 0 0
PTK6 promotes HIF1A stabilization R-HSA-8857538 1.487154e-01 0.828 0 0
Chylomicron clearance R-HSA-8964026 1.487154e-01 0.828 0 0
G2/M DNA replication checkpoint R-HSA-69478 1.487154e-01 0.828 0 0
Uncoating of the HIV Virion R-HSA-162585 1.487154e-01 0.828 0 0
E2F-enabled inhibition of pre-replication complex formation R-HSA-113507 1.487154e-01 0.828 0 0
Activation of NIMA Kinases NEK9, NEK6, NEK7 R-HSA-2980767 1.487154e-01 0.828 0 0
VLDL assembly R-HSA-8866423 1.487154e-01 0.828 0 0
Response of endothelial cells to shear stress R-HSA-9860931 1.526325e-01 0.816 0 0
Opioid Signalling R-HSA-111885 1.526325e-01 0.816 0 0
Cyclin A/B1/B2 associated events during G2/M transition R-HSA-69273 1.548122e-01 0.810 0 0
Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-399721 1.548122e-01 0.810 0 0
RSV-host interactions R-HSA-9833110 1.559637e-01 0.807 0 0
Regulated Necrosis R-HSA-5218859 1.563820e-01 0.806 0 0
Glucagon signaling in metabolic regulation R-HSA-163359 1.610494e-01 0.793 0 0
NFE2L2 regulating anti-oxidant/detoxification enzymes R-HSA-9818027 1.610494e-01 0.793 0 0
Regulation of PTEN localization R-HSA-8948747 1.638140e-01 0.786 0 0
Recycling of eIF2:GDP R-HSA-72731 1.638140e-01 0.786 0 0
LDL remodeling R-HSA-8964041 1.638140e-01 0.786 0 0
RAF activation R-HSA-5673000 1.673318e-01 0.776 0 0
Nuclear import of Rev protein R-HSA-180746 1.673318e-01 0.776 0 0
Processing of Capped Intron-Containing Pre-mRNA R-HSA-72203 1.702619e-01 0.769 0 0
Interconversion of nucleotide di- and triphosphates R-HSA-499943 1.736430e-01 0.760 0 0
Nuclear Pore Complex (NPC) Disassembly R-HSA-3301854 1.736556e-01 0.760 0 0
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells R-HSA-9860927 1.736556e-01 0.760 0 0
Asparagine N-linked glycosylation R-HSA-446203 1.737069e-01 0.760 0 0
TCR signaling R-HSA-202403 1.765009e-01 0.753 0 0
Reverse Transcription of HIV RNA R-HSA-162589 1.786457e-01 0.748 0 0
Minus-strand DNA synthesis R-HSA-164516 1.786457e-01 0.748 0 0
Type I hemidesmosome assembly R-HSA-446107 1.786457e-01 0.748 0 0
EGFR interacts with phospholipase C-gamma R-HSA-212718 1.786457e-01 0.748 0 0
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation R-HSA-9828211 1.786457e-01 0.748 0 0
Formyl peptide receptors bind formyl peptides and many other ligands R-HSA-444473 1.786457e-01 0.748 0 0
Adrenoceptors R-HSA-390696 1.786457e-01 0.748 0 0
Apoptotic cleavage of cell adhesion proteins R-HSA-351906 1.786457e-01 0.748 0 0
Interleukin-23 signaling R-HSA-9020933 1.786457e-01 0.748 0 0
AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-450408 1.800176e-01 0.745 0 0
G1/S-Specific Transcription R-HSA-69205 1.800176e-01 0.745 0 0
Regulation of TP53 Degradation R-HSA-6804757 1.800176e-01 0.745 0 0
Signaling by NOTCH4 R-HSA-9013694 1.824678e-01 0.739 0 0
Deactivation of the beta-catenin transactivating complex R-HSA-3769402 1.864142e-01 0.730 0 0
Ovarian tumor domain proteases R-HSA-5689896 1.864142e-01 0.730 0 0
Gene expression (Transcription) R-HSA-74160 1.882203e-01 0.725 0 0
Cellular responses to mechanical stimuli R-HSA-9855142 1.906765e-01 0.720 0 0
Rev-mediated nuclear export of HIV RNA R-HSA-165054 1.928425e-01 0.715 0 0
Transcriptional regulation of pluripotent stem cells R-HSA-452723 1.928425e-01 0.715 0 0
Lipophagy R-HSA-9613354 1.932153e-01 0.714 0 0
ARMS-mediated activation R-HSA-170984 1.932153e-01 0.714 0 0
Calcineurin activates NFAT R-HSA-2025928 1.932153e-01 0.714 0 0
MASTL Facilitates Mitotic Progression R-HSA-2465910 1.932153e-01 0.714 0 0
NOTCH4 Activation and Transmission of Signal to the Nucleus R-HSA-9013700 1.932153e-01 0.714 0 0
Caspase-mediated cleavage of cytoskeletal proteins R-HSA-264870 1.932153e-01 0.714 0 0
NS1 Mediated Effects on Host Pathways R-HSA-168276 1.992992e-01 0.700 0 0
Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin R-HSA-9725554 1.992992e-01 0.700 0 0
Signaling by ALK R-HSA-201556 1.992992e-01 0.700 0 0
Regulation of TP53 Expression and Degradation R-HSA-6806003 1.992992e-01 0.700 0 0
PCP/CE pathway R-HSA-4086400 2.004602e-01 0.698 0 0
Aerobic respiration and respiratory electron transport R-HSA-1428517 2.012047e-01 0.696 0 0
Interactions of Rev with host cellular proteins R-HSA-177243 2.057813e-01 0.687 0 0
Binding and entry of HIV virion R-HSA-173107 2.075273e-01 0.683 0 0
Regulation of CDH11 function R-HSA-9762292 2.075273e-01 0.683 0 0
Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA R-HSA-428359 2.075273e-01 0.683 0 0
MAPK3 (ERK1) activation R-HSA-110056 2.075273e-01 0.683 0 0
Signal attenuation R-HSA-74749 2.075273e-01 0.683 0 0
SPOP-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929491 2.122859e-01 0.673 0 0
M-decay: degradation of maternal mRNAs by maternally stored factors R-HSA-9820841 2.122859e-01 0.673 0 0
Degradation of GLI2 by the proteasome R-HSA-5610783 2.188101e-01 0.660 0 0
GLI3 is processed to GLI3R by the proteasome R-HSA-5610785 2.188101e-01 0.660 0 0
Negative regulation of MAPK pathway R-HSA-5675221 2.188101e-01 0.660 0 0
Degradation of GLI1 by the proteasome R-HSA-5610780 2.188101e-01 0.660 0 0
InlA-mediated entry of Listeria monocytogenes into host cells R-HSA-8876493 2.215862e-01 0.654 0 0
vRNP Assembly R-HSA-192905 2.215862e-01 0.654 0 0
Chylomicron assembly R-HSA-8963888 2.215862e-01 0.654 0 0
Dissolution of Fibrin Clot R-HSA-75205 2.215862e-01 0.654 0 0
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion R-HSA-381676 2.253514e-01 0.647 0 0
MTOR signalling R-HSA-165159 2.253514e-01 0.647 0 0
Interleukin-3, Interleukin-5 and GM-CSF signaling R-HSA-512988 2.253514e-01 0.647 0 0
TGF-beta receptor signaling activates SMADs R-HSA-2173789 2.319069e-01 0.635 0 0
Response of Mtb to phagocytosis R-HSA-9637690 2.319069e-01 0.635 0 0
Synthesis of diphthamide-EEF2 R-HSA-5358493 2.353966e-01 0.628 0 0
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 R-HSA-9824878 2.353966e-01 0.628 0 0
APOBEC3G mediated resistance to HIV-1 infection R-HSA-180689 2.353966e-01 0.628 0 0
TICAM1-dependent activation of IRF3/IRF7 R-HSA-9013973 2.353966e-01 0.628 0 0
Viral RNP Complexes in the Host Cell Nucleus R-HSA-168330 2.353966e-01 0.628 0 0
Condensation of Prometaphase Chromosomes R-HSA-2514853 2.353966e-01 0.628 0 0
Activation of RAC1 R-HSA-428540 2.353966e-01 0.628 0 0
Integration of provirus R-HSA-162592 2.353966e-01 0.628 0 0
G1 Phase R-HSA-69236 2.384742e-01 0.623 0 0
Cyclin D associated events in G1 R-HSA-69231 2.384742e-01 0.623 0 0
NEP/NS2 Interacts with the Cellular Export Machinery R-HSA-168333 2.450508e-01 0.611 0 0
ADORA2B mediated anti-inflammatory cytokines production R-HSA-9660821 2.450508e-01 0.611 0 0
Vasopressin regulates renal water homeostasis via Aquaporins R-HSA-432040 2.450508e-01 0.611 0 0
Somitogenesis R-HSA-9824272 2.450508e-01 0.611 0 0
Defective EXT1 causes exostoses 1, TRPS2 and CHDS R-HSA-3656253 2.489628e-01 0.604 0 0
Defective EXT2 causes exostoses 2 R-HSA-3656237 2.489628e-01 0.604 0 0
GRB2 events in EGFR signaling R-HSA-179812 2.489628e-01 0.604 0 0
Repression of WNT target genes R-HSA-4641265 2.489628e-01 0.604 0 0
Advanced glycosylation endproduct receptor signaling R-HSA-879415 2.489628e-01 0.604 0 0
Pervasive developmental disorders R-HSA-9005895 2.489628e-01 0.604 0 0
Loss of function of MECP2 in Rett syndrome R-HSA-9005891 2.489628e-01 0.604 0 0
Disorders of Nervous System Development R-HSA-9697154 2.489628e-01 0.604 0 0
OAS antiviral response R-HSA-8983711 2.489628e-01 0.604 0 0
Cellular response to chemical stress R-HSA-9711123 2.590277e-01 0.587 0 0
Formation of the non-canonical BAF (ncBAF) complex R-HSA-9933947 2.622891e-01 0.581 0 0
Frs2-mediated activation R-HSA-170968 2.622891e-01 0.581 0 0
CD28 dependent Vav1 pathway R-HSA-389359 2.622891e-01 0.581 0 0
Golgi Cisternae Pericentriolar Stack Reorganization R-HSA-162658 2.622891e-01 0.581 0 0
Platelet Adhesion to exposed collagen R-HSA-75892 2.622891e-01 0.581 0 0
Nuclear events stimulated by ALK signaling in cancer R-HSA-9725371 2.648129e-01 0.577 0 0
Transcriptional Regulation by MECP2 R-HSA-8986944 2.661204e-01 0.575 0 0
Formation of the canonical BAF (cBAF) complex R-HSA-9933937 2.753798e-01 0.560 0 0
Formation of the polybromo-BAF (pBAF) complex R-HSA-9933939 2.753798e-01 0.560 0 0
Respiratory syncytial virus genome transcription R-HSA-9828642 2.753798e-01 0.560 0 0
Malate-aspartate shuttle R-HSA-9856872 2.753798e-01 0.560 0 0
Regulation of KIT signaling R-HSA-1433559 2.753798e-01 0.560 0 0
Collagen formation R-HSA-1474290 2.853775e-01 0.545 0 0
SHC1 events in EGFR signaling R-HSA-180336 2.882390e-01 0.540 0 0
IRF3-mediated induction of type I IFN R-HSA-3270619 2.882390e-01 0.540 0 0
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA R-HSA-450385 2.882390e-01 0.540 0 0
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA R-HSA-450513 2.882390e-01 0.540 0 0
Protein lipoylation R-HSA-9857492 2.882390e-01 0.540 0 0
Formation of the embryonic stem cell BAF (esBAF) complex R-HSA-9933946 2.882390e-01 0.540 0 0
Other semaphorin interactions R-HSA-416700 2.882390e-01 0.540 0 0
DDX58/IFIH1-mediated induction of interferon-alpha/beta R-HSA-168928 2.902111e-01 0.537 0 0
Golgi Associated Vesicle Biogenesis R-HSA-432722 2.977284e-01 0.526 0 0
Phosphorylation of the APC/C R-HSA-176412 3.008707e-01 0.522 0 0
Prolonged ERK activation events R-HSA-169893 3.008707e-01 0.522 0 0
KSRP (KHSRP) binds and destabilizes mRNA R-HSA-450604 3.008707e-01 0.522 0 0
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest R-HSA-6804116 3.008707e-01 0.522 0 0
SARS-CoV-2 modulates host translation machinery R-HSA-9754678 3.042906e-01 0.517 0 0
Regulation of insulin secretion R-HSA-422356 3.095967e-01 0.509 0 0
Defective B3GALT6 causes EDSP2 and SEMDJL1 R-HSA-4420332 3.132791e-01 0.504 0 0
Defective B4GALT7 causes EDS, progeroid type R-HSA-3560783 3.132791e-01 0.504 0 0
The CRY:PER:kinase complex represses transactivation by the BMAL:CLOCK (ARNTL:CLOCK) complex R-HSA-9931521 3.132791e-01 0.504 0 0
Fibronectin matrix formation R-HSA-1566977 3.132791e-01 0.504 0 0
TRAF3-dependent IRF activation pathway R-HSA-918233 3.132791e-01 0.504 0 0
Regulation of innate immune responses to cytosolic DNA R-HSA-3134975 3.132791e-01 0.504 0 0
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) R-HSA-936964 3.132791e-01 0.504 0 0
Acetylcholine regulates insulin secretion R-HSA-399997 3.132791e-01 0.504 0 0
Disorders of Developmental Biology R-HSA-9675151 3.132791e-01 0.504 0 0
Defective B3GAT3 causes JDSSDHD R-HSA-3560801 3.254679e-01 0.487 0 0
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se R-HSA-2408550 3.254679e-01 0.487 0 0
Deadenylation-dependent mRNA decay R-HSA-429914 3.369023e-01 0.472 0 0
GAB1 signalosome R-HSA-180292 3.374412e-01 0.472 0 0
ZBP1(DAI) mediated induction of type I IFNs R-HSA-1606322 3.374412e-01 0.472 0 0
Mitotic G1 phase and G1/S transition R-HSA-453279 3.377087e-01 0.471 0 0
Cargo recognition for clathrin-mediated endocytosis R-HSA-8856825 3.387367e-01 0.470 0 0
Regulation of PTEN gene transcription R-HSA-8943724 3.433740e-01 0.464 0 0
Metabolism of carbohydrates and carbohydrate derivatives R-HSA-71387 3.477742e-01 0.459 0 0
APC/C:Cdc20 mediated degradation of Cyclin B R-HSA-174048 3.492026e-01 0.457 0 0
Mechanical load activates signaling by PIEZO1 and integrins in osteocytes R-HSA-9856532 3.492026e-01 0.457 0 0
STING mediated induction of host immune responses R-HSA-1834941 3.492026e-01 0.457 0 0
E2F mediated regulation of DNA replication R-HSA-113510 3.492026e-01 0.457 0 0
The NLRP3 inflammasome R-HSA-844456 3.492026e-01 0.457 0 0
Aquaporin-mediated transport R-HSA-445717 3.498254e-01 0.456 0 0
Formation of paraxial mesoderm R-HSA-9793380 3.498254e-01 0.456 0 0
Mitochondrial protein import R-HSA-1268020 3.562553e-01 0.448 0 0
Regulation of APC/C activators between G1/S and early anaphase R-HSA-176408 3.562553e-01 0.448 0 0
tRNA processing in the nucleus R-HSA-6784531 3.562553e-01 0.448 0 0
Signaling by ALK fusions and activated point mutants R-HSA-9725370 3.581316e-01 0.446 0 0
Signaling by ALK in cancer R-HSA-9700206 3.581316e-01 0.446 0 0
Formation of ATP by chemiosmotic coupling R-HSA-163210 3.607560e-01 0.443 0 0
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) R-HSA-9934037 3.607560e-01 0.443 0 0
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane R-HSA-9609523 3.607560e-01 0.443 0 0
BBSome-mediated cargo-targeting to cilium R-HSA-5620922 3.607560e-01 0.443 0 0
Protein hydroxylation R-HSA-9629569 3.607560e-01 0.443 0 0
Nephrin family interactions R-HSA-373753 3.607560e-01 0.443 0 0
rRNA modification in the nucleus and cytosol R-HSA-6790901 3.626624e-01 0.440 0 0
PD-L1(CD274) glycosylation and translocation to plasma membrane R-HSA-9931295 3.721050e-01 0.429 0 0
Early Phase of HIV Life Cycle R-HSA-162594 3.721050e-01 0.429 0 0
TNFR1-induced proapoptotic signaling R-HSA-5357786 3.721050e-01 0.429 0 0
Unblocking of NMDA receptors, glutamate binding and activation R-HSA-438066 3.832532e-01 0.417 0 0
Ras activation upon Ca2+ influx through NMDA receptor R-HSA-442982 3.832532e-01 0.417 0 0
Attachment and Entry R-HSA-9694614 3.832532e-01 0.417 0 0
Listeria monocytogenes entry into host cells R-HSA-8876384 3.832532e-01 0.417 0 0
Negative regulation of NMDA receptor-mediated neuronal transmission R-HSA-9617324 3.832532e-01 0.417 0 0
Assembly Of The HIV Virion R-HSA-175474 3.832532e-01 0.417 0 0
LDL clearance R-HSA-8964038 3.942041e-01 0.404 0 0
NOTCH3 Activation and Transmission of Signal to the Nucleus R-HSA-9013507 3.942041e-01 0.404 0 0
RAF-independent MAPK1/3 activation R-HSA-112409 3.942041e-01 0.404 0 0
Downregulation of TGF-beta receptor signaling R-HSA-2173788 3.942041e-01 0.404 0 0
Collagen biosynthesis and modifying enzymes R-HSA-1650814 3.943152e-01 0.404 0 0
Formation of the ureteric bud R-HSA-9830674 4.049612e-01 0.393 0 0
Estrogen-dependent nuclear events downstream of ESR-membrane signaling R-HSA-9634638 4.049612e-01 0.393 0 0
Downstream signaling events of B Cell Receptor (BCR) R-HSA-1168372 4.067780e-01 0.391 0 0
Regulation of mitotic cell cycle R-HSA-453276 4.129632e-01 0.384 0 0
APC/C-mediated degradation of cell cycle proteins R-HSA-174143 4.129632e-01 0.384 0 0
Retinoid metabolism and transport R-HSA-975634 4.129632e-01 0.384 0 0
Mitochondrial RNA degradation R-HSA-9836573 4.155280e-01 0.381 0 0
trans-Golgi Network Vesicle Budding R-HSA-199992 4.191163e-01 0.378 0 0
ATP-dependent chromatin remodelers R-HSA-9932444 4.259078e-01 0.371 0 0
SWI/SNF chromatin remodelers R-HSA-9932451 4.259078e-01 0.371 0 0
MicroRNA (miRNA) biogenesis R-HSA-203927 4.259078e-01 0.371 0 0
PIWI-interacting RNA (piRNA) biogenesis R-HSA-5601884 4.259078e-01 0.371 0 0
Signaling by FLT3 fusion proteins R-HSA-9703465 4.361038e-01 0.360 0 0
Postmitotic nuclear pore complex (NPC) reformation R-HSA-9615933 4.361038e-01 0.360 0 0
MET activates PTK2 signaling R-HSA-8874081 4.361038e-01 0.360 0 0
Synthesis of PIPs at the Golgi membrane R-HSA-1660514 4.361038e-01 0.360 0 0
Regulation of RUNX1 Expression and Activity R-HSA-8934593 4.361038e-01 0.360 0 0
G alpha (s) signalling events R-HSA-418555 4.417487e-01 0.355 0 0
C-type lectin receptors (CLRs) R-HSA-5621481 4.417487e-01 0.355 0 0
Phosphorylation of CD3 and TCR zeta chains R-HSA-202427 4.461194e-01 0.351 0 0
Cristae formation R-HSA-8949613 4.461194e-01 0.351 0 0
Insulin processing R-HSA-264876 4.461194e-01 0.351 0 0
Maturation of hRSV A proteins R-HSA-9828806 4.461194e-01 0.351 0 0
Leishmania infection R-HSA-9658195 4.516116e-01 0.345 0 0
Parasitic Infection Pathways R-HSA-9824443 4.516116e-01 0.345 0 0
HIV Infection R-HSA-162906 4.527973e-01 0.344 0 0
Insulin receptor recycling R-HSA-77387 4.559577e-01 0.341 0 0
PINK1-PRKN Mediated Mitophagy R-HSA-5205685 4.559577e-01 0.341 0 0
Telomere Extension By Telomerase R-HSA-171319 4.559577e-01 0.341 0 0
Inflammasomes R-HSA-622312 4.559577e-01 0.341 0 0
G1/S Transition R-HSA-69206 4.577457e-01 0.339 0 0
Innate Immune System R-HSA-168249 4.582024e-01 0.339 1 0
Developmental Lineage of Pancreatic Acinar Cells R-HSA-9925561 4.612283e-01 0.336 0 0
FCGR3A-mediated IL10 synthesis R-HSA-9664323 4.623437e-01 0.335 0 0
Late endosomal microautophagy R-HSA-9615710 4.656219e-01 0.332 0 0
Regulation of CDH11 Expression and Function R-HSA-9759475 4.656219e-01 0.332 0 0
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells R-HSA-9856530 4.670993e-01 0.331 0 0
Signaling by FGFR2 R-HSA-5654738 4.670993e-01 0.331 0 0
Respiratory electron transport R-HSA-611105 4.690829e-01 0.329 0 0
Metabolism of fat-soluble vitamins R-HSA-6806667 4.729322e-01 0.325 0 0
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) R-HSA-5619107 4.751149e-01 0.323 0 0
Activation of the pre-replicative complex R-HSA-68962 4.751149e-01 0.323 0 0
GABA synthesis, release, reuptake and degradation R-HSA-888590 4.751149e-01 0.323 0 0
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation R-HSA-1474151 4.751149e-01 0.323 0 0
Interleukin-37 signaling R-HSA-9008059 4.751149e-01 0.323 0 0
Downstream signal transduction R-HSA-186763 4.844399e-01 0.315 0 0
IP3 and IP4 transport between cytosol and nucleus R-HSA-1855196 4.844399e-01 0.315 0 0
Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-211733 4.844399e-01 0.315 0 0
IP6 and IP7 transport between cytosol and nucleus R-HSA-1855229 4.844399e-01 0.315 0 0
EGFR downregulation R-HSA-182971 4.844399e-01 0.315 0 0
Budding and maturation of HIV virion R-HSA-162588 4.844399e-01 0.315 0 0
Molecules associated with elastic fibres R-HSA-2129379 4.844399e-01 0.315 0 0
Evasion by RSV of host interferon responses R-HSA-9833109 4.844399e-01 0.315 0 0
Negative regulators of DDX58/IFIH1 signaling R-HSA-936440 4.844399e-01 0.315 0 0
HS-GAG degradation R-HSA-2024096 4.935998e-01 0.307 0 0
Signaling by WNT in cancer R-HSA-4791275 4.935998e-01 0.307 0 0
Protein-protein interactions at synapses R-HSA-6794362 4.958744e-01 0.305 0 0
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal R-HSA-141444 5.015104e-01 0.300 0 0
Amplification of signal from the kinetochores R-HSA-141424 5.015104e-01 0.300 0 0
Regulation of PD-L1(CD274) Post-translational modification R-HSA-9909615 5.015104e-01 0.300 0 0
RAB GEFs exchange GTP for GDP on RABs R-HSA-8876198 5.015104e-01 0.300 0 0
IPs transport between nucleus and cytosol R-HSA-1855170 5.025975e-01 0.299 0 0
Transport of the SLBP independent Mature mRNA R-HSA-159227 5.025975e-01 0.299 0 0
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling R-HSA-442742 5.025975e-01 0.299 0 0
Regulation of Expression and Function of Type II Classical Cadherins R-HSA-9764260 5.025975e-01 0.299 0 0
Activation of ATR in response to replication stress R-HSA-176187 5.025975e-01 0.299 0 0
Regulation of MECP2 expression and activity R-HSA-9022692 5.025975e-01 0.299 0 0
Synthesis of IP3 and IP4 in the cytosol R-HSA-1855204 5.025975e-01 0.299 0 0
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation R-HSA-163841 5.071058e-01 0.295 0 0
XBP1(S) activates chaperone genes R-HSA-381038 5.071058e-01 0.295 0 0
Transport of the SLBP Dependant Mature mRNA R-HSA-159230 5.114359e-01 0.291 0 0
Association of TriC/CCT with target proteins during biosynthesis R-HSA-390471 5.114359e-01 0.291 0 0
Regulation of Glucokinase by Glucokinase Regulatory Protein R-HSA-170822 5.114359e-01 0.291 0 0
DNA Damage Recognition in GG-NER R-HSA-5696394 5.114359e-01 0.291 0 0
Effects of PIP2 hydrolysis R-HSA-114508 5.114359e-01 0.291 0 0
Integration of energy metabolism R-HSA-163685 5.160989e-01 0.287 0 0
Beta-catenin independent WNT signaling R-HSA-3858494 5.160989e-01 0.287 0 0
Glycosaminoglycan-protein linkage region biosynthesis R-HSA-1971475 5.201178e-01 0.284 0 0
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding R-HSA-6814122 5.201178e-01 0.284 0 0
eNOS activation R-HSA-203615 5.201178e-01 0.284 0 0
Mitophagy R-HSA-5205647 5.201178e-01 0.284 0 0
Hyaluronan metabolism R-HSA-2142845 5.201178e-01 0.284 0 0
Regulation of Apoptosis R-HSA-169911 5.286459e-01 0.277 0 0
Signalling to ERKs R-HSA-187687 5.286459e-01 0.277 0 0
Oncogene Induced Senescence R-HSA-2559585 5.286459e-01 0.277 0 0
Downstream TCR signaling R-HSA-202424 5.290752e-01 0.276 0 0
PTEN Regulation R-HSA-6807070 5.290880e-01 0.276 0 0
FCGR3A-mediated phagocytosis R-HSA-9664422 5.333746e-01 0.273 0 0
Leishmania phagocytosis R-HSA-9664417 5.333746e-01 0.273 0 0
Parasite infection R-HSA-9664407 5.333746e-01 0.273 0 0
HS-GAG biosynthesis R-HSA-2022928 5.370230e-01 0.270 0 0
FLT3 signaling in disease R-HSA-9682385 5.370230e-01 0.270 0 0
Lysosome Vesicle Biogenesis R-HSA-432720 5.370230e-01 0.270 0 0
IRE1alpha activates chaperones R-HSA-381070 5.398089e-01 0.268 0 0
Vpr-mediated nuclear import of PICs R-HSA-180910 5.452517e-01 0.263 0 0
TRAF6 mediated IRF7 activation R-HSA-933541 5.452517e-01 0.263 0 0
Metabolism of folate and pterines R-HSA-196757 5.452517e-01 0.263 0 0
Late Phase of HIV Life Cycle R-HSA-162599 5.461018e-01 0.263 0 0
Metabolism of nitric oxide: NOS3 activation and regulation R-HSA-202131 5.533346e-01 0.257 0 0
Elastic fibre formation R-HSA-1566948 5.533346e-01 0.257 0 0
MET promotes cell motility R-HSA-8875878 5.533346e-01 0.257 0 0
GSK3B-mediated proteasomal degradation of PD-L1(CD274) R-HSA-9929356 5.612744e-01 0.251 0 0
Transport of Mature mRNA Derived from an Intronless Transcript R-HSA-159231 5.612744e-01 0.251 0 0
Plasma lipoprotein clearance R-HSA-8964043 5.612744e-01 0.251 0 0
Visual phototransduction R-HSA-2187338 5.668587e-01 0.247 0 0
Transport of Mature mRNAs Derived from Intronless Transcripts R-HSA-159234 5.690735e-01 0.245 0 0
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 R-HSA-9844594 5.690735e-01 0.245 0 0
Transcriptional regulation of brown and beige adipocyte differentiation R-HSA-9843743 5.690735e-01 0.245 0 0
Interactions of Vpr with host cellular proteins R-HSA-176033 5.690735e-01 0.245 0 0
Negative regulation of NOTCH4 signaling R-HSA-9604323 5.690735e-01 0.245 0 0
Signaling by TGF-beta Receptor Complex R-HSA-170834 5.760316e-01 0.240 0 0
Transport of Ribonucleoproteins into the Host Nucleus R-HSA-168271 5.767345e-01 0.239 0 0
MITF-M-dependent gene expression R-HSA-9856651 5.790314e-01 0.237 0 0
Post-translational protein phosphorylation R-HSA-8957275 5.810338e-01 0.236 0 0
Signaling by FGFR R-HSA-190236 5.810338e-01 0.236 0 0
KEAP1-NFE2L2 pathway R-HSA-9755511 5.830411e-01 0.234 0 0
Mitotic Spindle Checkpoint R-HSA-69618 5.909080e-01 0.228 0 0
Protein localization R-HSA-9609507 5.909877e-01 0.228 0 0
Extra-nuclear estrogen signaling R-HSA-9009391 5.957800e-01 0.225 0 0
Signaling by SCF-KIT R-HSA-1433557 5.989125e-01 0.223 0 0
PI Metabolism R-HSA-1483255 6.006085e-01 0.221 0 0
SCF(Skp2)-mediated degradation of p27/p21 R-HSA-187577 6.060447e-01 0.217 0 0
Amine ligand-binding receptors R-HSA-375280 6.060447e-01 0.217 0 0
HIV Life Cycle R-HSA-162587 6.065866e-01 0.217 0 0
Signaling by the B Cell Receptor (BCR) R-HSA-983705 6.104244e-01 0.214 0 0
Diseases associated with glycosaminoglycan metabolism R-HSA-3560782 6.130506e-01 0.213 0 0
Regulation of MITF-M-dependent genes involved in pigmentation R-HSA-9824585 6.130506e-01 0.213 0 0
Cell recruitment (pro-inflammatory response) R-HSA-9664424 6.199322e-01 0.208 0 0
Purinergic signaling in leishmaniasis infection R-HSA-9660826 6.199322e-01 0.208 0 0
Regulation of pyruvate metabolism R-HSA-9861718 6.199322e-01 0.208 0 0
Inactivation, recovery and regulation of the phototransduction cascade R-HSA-2514859 6.199322e-01 0.208 0 0
Regulation of TNFR1 signaling R-HSA-5357905 6.199322e-01 0.208 0 0
Co-stimulation by CD28 R-HSA-389356 6.333318e-01 0.198 0 0
Plasma lipoprotein remodeling R-HSA-8963899 6.333318e-01 0.198 0 0
Degradation of CDH1 R-HSA-9766229 6.398540e-01 0.194 0 0
p53-Dependent G1 DNA Damage Response R-HSA-69563 6.398540e-01 0.194 0 0
p53-Dependent G1/S DNA damage checkpoint R-HSA-69580 6.398540e-01 0.194 0 0
Azathioprine ADME R-HSA-9748787 6.462606e-01 0.190 0 0
Inositol phosphate metabolism R-HSA-1483249 6.508654e-01 0.187 0 0
Complex IV assembly R-HSA-9864848 6.525536e-01 0.185 0 0
Activation of NF-kappaB in B cells R-HSA-1169091 6.525536e-01 0.185 0 0
Hedgehog ligand biogenesis R-HSA-5358346 6.525536e-01 0.185 0 0
The phototransduction cascade R-HSA-2514856 6.525536e-01 0.185 0 0
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) R-HSA-9931269 6.587351e-01 0.181 0 0
Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-174184 6.587351e-01 0.181 0 0
Orc1 removal from chromatin R-HSA-68949 6.587351e-01 0.181 0 0
Neurexins and neuroligins R-HSA-6794361 6.587351e-01 0.181 0 0
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) R-HSA-381426 6.636714e-01 0.178 0 0
Regulation of PTEN stability and activity R-HSA-8948751 6.648069e-01 0.177 0 0
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint R-HSA-179419 6.648069e-01 0.177 0 0
Leishmania parasite growth and survival R-HSA-9664433 6.683883e-01 0.175 0 0
Anti-inflammatory response favouring Leishmania parasite infection R-HSA-9662851 6.683883e-01 0.175 0 0
CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69017 6.707711e-01 0.173 0 0
Role of phospholipids in phagocytosis R-HSA-2029485 6.719977e-01 0.173 0 0
Interferon alpha/beta signaling R-HSA-909733 6.719977e-01 0.173 0 0
APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176409 6.766295e-01 0.170 0 0
Paracetamol ADME R-HSA-9753281 6.766295e-01 0.170 0 0
Signaling by NOTCH3 R-HSA-9012852 6.766295e-01 0.170 0 0
Rab regulation of trafficking R-HSA-9007101 6.801566e-01 0.167 0 0
Signaling by EGFR R-HSA-177929 6.823840e-01 0.166 0 0
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins R-HSA-176814 6.823840e-01 0.166 0 0
Ion homeostasis R-HSA-5578775 6.823840e-01 0.166 0 0
TNF signaling R-HSA-75893 6.823840e-01 0.166 0 0
Early SARS-CoV-2 Infection Events R-HSA-9772572 6.935887e-01 0.159 0 0
Infection with Mycobacterium tuberculosis R-HSA-9635486 6.959781e-01 0.157 0 0
Nuclear events mediated by NFE2L2 R-HSA-9759194 6.959781e-01 0.157 0 0
Heparan sulfate/heparin (HS-GAG) metabolism R-HSA-1638091 6.990424e-01 0.155 0 0
Metabolism of non-coding RNA R-HSA-194441 6.990424e-01 0.155 0 0
snRNP Assembly R-HSA-191859 6.990424e-01 0.155 0 0
Extension of Telomeres R-HSA-180786 6.990424e-01 0.155 0 0
Assembly of collagen fibrils and other multimeric structures R-HSA-2022090 6.990424e-01 0.155 0 0
RAB geranylgeranylation R-HSA-8873719 7.043994e-01 0.152 0 0
Viral Messenger RNA Synthesis R-HSA-168325 7.096613e-01 0.149 0 0
Signaling by PDGF R-HSA-186797 7.148300e-01 0.146 0 0
NCAM signaling for neurite out-growth R-HSA-375165 7.148300e-01 0.146 0 0
Synthesis of PIPs at the plasma membrane R-HSA-1660499 7.148300e-01 0.146 0 0
Complex I biogenesis R-HSA-6799198 7.199069e-01 0.143 0 0
G1/S DNA Damage Checkpoints R-HSA-69615 7.199069e-01 0.143 0 0
CD22 mediated BCR regulation R-HSA-5690714 7.248937e-01 0.140 0 0
Insulin receptor signalling cascade R-HSA-74751 7.248937e-01 0.140 0 0
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways R-HSA-168643 7.248937e-01 0.140 0 0
Kidney development R-HSA-9830369 7.393296e-01 0.131 0 0
Adipogenesis R-HSA-9843745 7.395955e-01 0.131 0 0
Circadian clock R-HSA-9909396 7.429784e-01 0.129 0 0
Bacterial Infection Pathways R-HSA-9824439 7.453126e-01 0.128 0 0
G alpha (q) signalling events R-HSA-416476 7.484428e-01 0.126 0 0
Cyclin E associated events during G1/S transition R-HSA-69202 7.530104e-01 0.123 0 0
Cytosolic sensors of pathogen-associated DNA R-HSA-1834949 7.530104e-01 0.123 0 0
Degradation of beta-catenin by the destruction complex R-HSA-195253 7.530104e-01 0.123 0 0
COPII-mediated vesicle transport R-HSA-204005 7.530104e-01 0.123 0 0
ECM proteoglycans R-HSA-3000178 7.574098e-01 0.121 0 0
Metabolism of cofactors R-HSA-8978934 7.574098e-01 0.121 0 0
Cyclin A:Cdk2-associated events at S phase entry R-HSA-69656 7.617311e-01 0.118 0 0
Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-159236 7.659756e-01 0.116 0 0
Switching of origins to a post-replicative state R-HSA-69052 7.659756e-01 0.116 0 0
Cell death signalling via NRAGE, NRIF and NADE R-HSA-204998 7.659756e-01 0.116 0 0
Ca2+ pathway R-HSA-4086398 7.659756e-01 0.116 0 0
Unfolded Protein Response (UPR) R-HSA-381119 7.687115e-01 0.114 0 0
Citric acid cycle (TCA cycle) R-HSA-71403 7.742400e-01 0.111 0 0
UCH proteinases R-HSA-5689603 7.782625e-01 0.109 0 0
Integrin cell surface interactions R-HSA-216083 7.860944e-01 0.105 0 0
Regulation of cholesterol biosynthesis by SREBP (SREBF) R-HSA-1655829 7.899063e-01 0.102 0 0
Signaling by MET R-HSA-6806834 7.936506e-01 0.100 0 0
Gastrulation R-HSA-9758941 8.004251e-01 0.097 0 0
Transport of Mature Transcript to Cytoplasm R-HSA-72202 8.009408e-01 0.096 0 0
Binding and Uptake of Ligands by Scavenger Receptors R-HSA-2173782 8.031088e-01 0.095 0 0
Cytoprotection by HMOX1 R-HSA-9707564 8.044890e-01 0.094 0 0
Global Genome Nucleotide Excision Repair (GG-NER) R-HSA-5696399 8.079743e-01 0.093 0 0
Death Receptor Signaling R-HSA-73887 8.135262e-01 0.090 0 0
Regulation of TP53 Activity through Phosphorylation R-HSA-6804756 8.180628e-01 0.087 0 0
Signaling by TGFB family members R-HSA-9006936 8.282323e-01 0.082 0 0
Regulation of TP53 Activity R-HSA-5633007 8.282323e-01 0.082 0 0
Neurotransmitter release cycle R-HSA-112310 8.306973e-01 0.081 0 0
Metabolism of nucleotides R-HSA-15869 8.372809e-01 0.077 0 0
Cell surface interactions at the vascular wall R-HSA-202733 8.391980e-01 0.076 0 0
Signaling by Insulin receptor R-HSA-74752 8.395958e-01 0.076 0 0
FCGR activation R-HSA-2029481 8.424572e-01 0.074 0 0
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers R-HSA-983695 8.424572e-01 0.074 0 0
Mitochondrial Fatty Acid Beta-Oxidation R-HSA-77289 8.480282e-01 0.072 0 0
tRNA processing R-HSA-72306 8.525117e-01 0.069 0 0
Transcriptional regulation of white adipocyte differentiation R-HSA-381340 8.534028e-01 0.069 0 0
CLEC7A (Dectin-1) signaling R-HSA-5607764 8.534028e-01 0.069 0 0
p75 NTR receptor-mediated signalling R-HSA-193704 8.611117e-01 0.065 0 0
ABC-family proteins mediated transport R-HSA-382556 8.635905e-01 0.064 0 0
Mitochondrial ribosome-associated quality control R-HSA-9937383 8.707654e-01 0.060 0 0
Toll Like Receptor 3 (TLR3) Cascade R-HSA-168164 8.775642e-01 0.057 0 0
Nucleotide Excision Repair R-HSA-5696398 8.775642e-01 0.057 0 0
Synthesis of DNA R-HSA-69239 8.818975e-01 0.055 0 0
G alpha (i) signalling events R-HSA-418594 8.821333e-01 0.054 0 0
TRIF (TICAM1)-mediated TLR4 signaling R-HSA-937061 8.881125e-01 0.052 0 0
MyD88-independent TLR4 cascade R-HSA-166166 8.881125e-01 0.052 0 0
FCERI mediated MAPK activation R-HSA-2871796 8.920736e-01 0.050 0 0
Glycosaminoglycan metabolism R-HSA-1630316 8.934784e-01 0.049 0 0
Peptide hormone metabolism R-HSA-2980736 9.048689e-01 0.043 0 0
Mitochondrial biogenesis R-HSA-1592230 9.048689e-01 0.043 0 0
Transcriptional regulation by RUNX2 R-HSA-8878166 9.082387e-01 0.042 0 0
Metabolism of vitamins and cofactors R-HSA-196854 9.136766e-01 0.039 0 0
Formation of the cornified envelope R-HSA-6809371 9.161519e-01 0.038 0 0
Signaling by NTRK1 (TRKA) R-HSA-187037 9.233848e-01 0.035 0 0
Cardiac conduction R-HSA-5576891 9.287207e-01 0.032 0 0
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-198933 9.379088e-01 0.028 0 0
Mitochondrial translation R-HSA-5368287 9.383068e-01 0.028 0 0
Metabolism of amino acids and derivatives R-HSA-71291 9.409940e-01 0.026 0 0
GPCR downstream signalling R-HSA-388396 9.485427e-01 0.023 0 0
S Phase R-HSA-69242 9.494249e-01 0.023 0 0
Toll Like Receptor 4 (TLR4) Cascade R-HSA-166016 9.494249e-01 0.023 0 0
Signaling by NTRKs R-HSA-166520 9.494249e-01 0.023 0 0
Interleukin-1 family signaling R-HSA-446652 9.529521e-01 0.021 0 0
PPARA activates gene expression R-HSA-1989781 9.554357e-01 0.020 0 0
Regulation of lipid metabolism by PPARalpha R-HSA-400206 9.570184e-01 0.019 0 0
Interferon gamma signaling R-HSA-877300 9.585450e-01 0.018 0 0
SLC transporter disorders R-HSA-5619102 9.641300e-01 0.016 0 0
Diseases of glycosylation R-HSA-3781865 9.741050e-01 0.011 0 0
Peptide ligand-binding receptors R-HSA-375276 9.750264e-01 0.011 0 0
Signaling by GPCR R-HSA-372790 9.770500e-01 0.010 0 0
Toll-like Receptor Cascades R-HSA-168898 9.771893e-01 0.010 0 0
Phospholipid metabolism R-HSA-1483257 9.771909e-01 0.010 0 0
Fc epsilon receptor (FCERI) signaling R-HSA-2454202 9.816489e-01 0.008 0 0
Keratinization R-HSA-6805567 9.829331e-01 0.007 0 0
Drug ADME R-HSA-9748784 9.862727e-01 0.006 0 0
Metabolism of water-soluble vitamins and cofactors R-HSA-196849 9.889606e-01 0.005 0 0
Disorders of transmembrane transporters R-HSA-5619115 9.918951e-01 0.004 0 0
Class A/1 (Rhodopsin-like receptors) R-HSA-373076 9.953254e-01 0.002 0 0
Phase I - Functionalization of compounds R-HSA-211945 9.953904e-01 0.002 0 0
Antigen processing: Ubiquitination & Proteasome degradation R-HSA-983168 9.957145e-01 0.002 0 0
Metabolism of steroids R-HSA-8957322 9.980089e-01 0.001 0 0
Class I MHC mediated antigen processing & presentation R-HSA-983169 9.993363e-01 0.000 0 0
Fatty acid metabolism R-HSA-8978868 9.995728e-01 0.000 0 0
Diseases of metabolism R-HSA-5668914 9.997042e-01 0.000 0 0
GPCR ligand binding R-HSA-500792 9.998175e-01 0.000 0 0
Sensory Perception R-HSA-9709957 9.999118e-01 0.000 0 0
Transport of small molecules R-HSA-382551 9.999374e-01 0.000 0 0
Biological oxidations R-HSA-211859 9.999497e-01 0.000 0 0
Metabolism R-HSA-1430728 9.999949e-01 0.000 0 0
Metabolism of lipids R-HSA-556833 9.999975e-01 0.000 0 0
Top15 pathways (red highlights are reference pathways)
Compared with reference pathways